Dragon09/odtu_chatbot huggingface dataset:
advanced technology for stationary energy storage systems in naion

atenas main objective is to contribute to improve the competitiveness of the european battery industry by demonstrating a new generation of safe sustainablebydesign highperformance costeffective and fully madeineurope sodiumion battery sib technology at preindustrial scale trl 7 by leveraging a multidisciplinary consortium of leading european research institutions and toptier industrial players atena will demonstrate the manufacturing of up to 80 ah and 25kwh modules representative of bess applications by i optimizing cuttingedge active materials ie stable cofree layered oxides with minimal ni content and improved energy density and processability eusourced biobased hard carbon made from sustainably managed forests with enhanced capacity efficiency and material density customized advanced electrolytes with interphasestabilizing characteristics highionic conductivity and high electrochemical stability ii developing environmentallyfriendly processing techniques for high performance electrode production iii improving cell and module architecture designs featuring high reparabilitylevel low maintenance requirement and enhanced safety performance and iv integrating an advanced bms with battery passport capabilities and finetuned soc management to achieve optimal cell performance all this supported by iterative feedback loops with thorough electrochemical and safety testing environmental ecodesign and recyclability criteriafinally the technology will be virtually upscaled to full bess level to evaluate the systems performance across 5 different real enduser operating conditions to accelerate postproject technology commercialization and ultimately contributing to the establishment of a competitive resilient and sustainable battery manufacturing industry in europe
development of metastatic organonachip for modelling the role of sex steroids in bladder cancer metastasis to bone

bladder cancer bca is the 5th most common cancer in europe with an annual economic burden of 5 billion despite efforts aimed at early detection and targeted therapies the development of metastatic bca 5 remains a major cause of mortality patient survival rate of only 21 recent evidence has strongly implicated a role of bone morphogenic proteins bmps in bca progression however their regulation remains poorly understood and their role in metastatic bca remains to be elucidated moreover there is paucity of understanding regarding the gender disparity in bca whereby men are 4 times more likely to be diagnosed compared to women who have worse prognosisdemobilise seeks to address this critical gap in the knowledge by investigating the synergistic role of sex steroids ss and bmps in bca bone metastasis this will be achieved by using single cell multiomics and crispr gene editing coupled with stateoftheart organonachip ooc technology and spatially resolved imaging of the bone perivascular niche within the ooc this study will thereby investigate at an unprecedented level of detail the functional role of bmp signalling and its synergy with ss in bca metastatic processesi will spend 2 years at columbia university usa expanding my skills in cancer models and single cell sequencing and also acquiring a new skillset in ooc fabrication i will return to the university of limerick ireland and receive training in steroidogenesis highdimensional imaging and mass spectrometry additionally i will have a 6month nonacademic placement in the startup company hooke bio who specialize in the development and utilisation of high throughput microfluidic systems for 3d microtissue drug screening i will be immersed within a multidisciplinary team with expertise in ooc fabrication bone metastasis and 3d cancer modelling that will support me in meeting my researchtraining objectives and prepare me for a career as an independent researcher
resolving the mechanism of plant cell expansion at high spatiotemporal resolution

plants critically shape ecosystems and our societies by converting sunlight and co2 into o2 and biomass while they grow understanding this growth process constitutes a major frontier in plant research growth is a multiscale process at a subcellular scale it depends on the expansion of the cell walls which involves changes in the chemistry and architecture of constituent polymer networks very little is known on the nature and the control of the cell wall changes that are critical for growth in striking contrast to the often detailed knowledge of growthregulating signaling networks this is in part due to the lack of appropriate tools to study changes in the complex cell wall polymer assemblies that often occur at fast s and small micrometer scales in this project i propose firstly to breach the spatial limits of the tools by using multitarget optical nanoscopy to visualize cell wall architecture and remodeling and secondly to overcome their temporal limits by using lightgated actuators and multiplexed intracellular biosensors to simultaneously perturb and monitor the system dynamics in vivo in particular i will address pectin remodeling the role of which in plant growth was shown to be critical but without clearly understanding the mechanism my objectives are to 1 reveal the key changes in cell wall architecture and chemistry during growth 2 understand the fast signaling by which cells perceive and coordinate wall remodeling and 3 build a dynamic hybrid model to explain how plants coordinate wall expansion this interdisciplinary project will provide new insights into the nanoscale organization of cell walls and propose a novel pectinbased mechanism for its active reorganization during growth this will provide an essential framework not only for understanding plant growth and morphogenesis but also for the study of life beyond the plasma membrane for instance in relation to immunity multicellularity or symbiosis
countering jihadi insurgencies in africa repress resist reorder

many african countries including libya nigeria mali dr congo somalia and mozambique have been affected by violence of jihadist armed groups these groups pose a distinct threat to social political and economic orders across africa as they violently reject the nationstate and can rely on support from the transnational violent networks of the islamic state and alqaeda research has primarily focused on international responses to violent extremism in africa but international actors do not operate in a vacuum and interact with responses on the ground if we want to understand and effectively tackle this violent threat we need to know more about how domestic actorsgovernments security forces and affected communitiescounter jihadist armed groups in africa why do some governments repress these groups through domestic security operations while others invite foreign countries to militarily intervene why do some governments respond immediately while others delay a response to a new jihadist threat why do some communities decide to cooperate with jihadist groups while others opt to resist them why do some communities attempt to resist these groups nonviolently while others form selfdefence militias to protect themselves and finally how do domestic responses to jihadist armed groups reorder security in the region and shape conflict stabilization or escalation counterrr will deliver crucial analyses of when how and why domestic actors repress and resist jihadist armed groups and reorder security it will adopt an innovative multilevel and multimethod comparative approach focused on variation within and across three countries mali nigeria and mozambique understanding how african countries and affected communities respond to jihadist insurgencies will help international actors to coordinate and adjust their responses to benefit from local knowledge and prevent further escalation of conflict
breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks

fruit tree crops ftc represented by more than 50 species grown on over 100 m ha are strongly affected by climate change cc thanks to grafting rootstocks can confer enhanced tolerance to abiotic and biotic stresses providing a valuable solution to expand food production bolero aims to i develop phenotyping tools ii employ them to score root system architecture rsa traits of coffeecocoa including grafted plants under controlled and onfield conditions iii decode the microbiome of coffeecocoa plants and the interface with the root exudates with largescale metabolic modelling and iv use these resources to build predictive models of rsa traits in terms of genotypic data and microbiome composition and abundance to accelerate coffeecocoa breeding this data compendium will be used in combination with a data hub to survey the genetic diversity in ftcs and use it to dissect the genetic basis of rsa traits and their plasticity bolero will propose fast and lowcost breeding strategies to create rootstocks which will be tested in lowinput coffeecocoa farming systems the agronomic performances and profitability of grafted plants will be assessed in vietnam bolero will rely on the knowledge of the large scientific community in europe the support of national institutes in tropical countries and the expertise of industries to lead a multidisciplinary study for rootstocks selection with coffee as a model cocoa as proof of concept and propose tools and techniques transferable easily to all ftcs bolero will develop and demonstrate for the first time at a large scale the opensource seeds initiative bolero will therefore contribute to the biodiversity and farm to fork strategies through significant impacts on the way ftcs are bred and on the use of beneficial soil biota and biodiversity leading on adaptation to cc inputs used and soil carbon sequestration
new mobility solutions for climate neutrality in eu cities

mobilities for eu aims at demonstrating that innovative passenger mobility and freight transport concepts designed and implemented following participative and usercenter principles are costeffective and feasible solutions to contribute significantly to the cities transformation towards climateneutrality allowing to speed up the process even to reach scope 2 emissions reduction in 2030madrid spain and dresden germany will implement 11 pilots comprising 27 very innovative solutions for mobility of people and freight exploiting the combined potential of electrification automation and connectivity from the design to the implementation and evaluation stages acting as lead cities lc both cities also ambition to act as pioneers of this process taking advantage of multiple already existing initiates of social engagement and empowerment that will be integrated in the idea of urban transport labs utlabs conceived as innovation hubs with the aim of fostering faster upscaling and replicability at eu level making 5 replication cities ioaninnagreece trencinslovakia espoofinland gdanskpoland and sarajevobosniaherzegovina through their own utlabs direct participants of the processes and later on main protagonists of their own designs
proportional algorithms for democratic decisions

the project is set in the field of computational social choice we will focus on formal models describing scenarios where a group of individuals called voters disagrees on certain matters yet needs to make a collective decision the decision must truly represents a compromise we focus on group fairness understood as proportionality there are numerous reallife scenarios that involve collective public decisions and where our solutions could be applied examples include elections of representative bodies such as parliaments faculty boards etc participatory budgeting elections where citizens decide how to allocate a part of a municipal budget or scenarios where certain local communities say housing cooperatives make series of decisions in addition proportional algorithms for making collective decisions can be used for selecting nominees for an award for constructing rankings of movies or books for selecting validators in consensus protocols such as the blockchain for constructing rankings of webpages in response to user queries for locating public facilities or for improving genetic algorithmsthe goal of this project is to develop generic methods of reasoning about equity of treatment of voters and to design new algorithms that satisfy the most demanding criteria of proportionality the new methods should be applicable to a number of specific models that concern public decisions we will 1 prove theorems specifying whether and under which conditions our notions of proportionality are satisfiable and 2 we will analyse various rules and algorithms with respect to our criteria of proportionality and other important desiderata that are commonly considered in social choice theory we plan to 3 determine the computational complexity of the problem of finding proportional public decisions and to 4 develop exact approximation fixedparametertractable and heuristic algorithms for this and related computational problems
illuminating neutron stars with radiative plasma physics

this research program will use firstprinciples radiative plasma simulations to understand how neutron stars radiate neutron stars are the culprits of the most infamous astrophysical emission enigmas 1 pulsar radio emission 2 multimessenger signals of compactobject binary mergers and 3 simultaneous generation of giant flares and fast radio bursts from magnetars these emission mechanisms have remained elusive because we do not have a selfconsistent theory that combines plasma physics describing microscopic motions and energy dissipation of the magnetized gas and radiative processes describing the reprocessing of the energy into radiationthis project combines the forefront plasma physics theory with exascale highperformance computing technologies to achieve two breakthroughs 1 generation of firstprinciples 3d models of the radiative plasmas around pulsars mergers and magnetars and 2 development of a novel opensource simulation toolkit for selfconsistent and highfidelity modeling of astroplasmas these enable a quantitative understanding of the unsolved emission mechanisms including efficiency variability and output spectra and direct comparison to observationsanalyzing astronomical observations with these superior physicsconstrained models enable direct tests of their validity and a leap in improving the accuracy of the modern nuclearparticle physics theories of the stillunknown neutron star equation of state the pi has a worldleading role in computational astroplasma physics an established record of impactful and innovative research in the astrophysics of neutron stars and 10 years of experience in stateoftheart highperformance computing solutions
chip urinary engineered system for modelling bladder biomechanics and disease

urinary tract infections uti are severe bacterial infections of the urinary system low understanding of specific bacteriahost interactions and associated disease aetiologies has led to global misuse of antibiotics driving bacterial resistance however relevant human modelling platforms that replicate all parameters of a physiological bladder and reciprocate infection conditions are nonexistent during infection bladder stretchmechanisms are commandeered by opportunistic bacteria to penetrate the impermeable bladder defence that are then not appropriately cleared by antibiotics regimens with curies we will develop microfluidic bladderonchip systems able to replicate the dynamic biomechanical scenarios and chemicallyrich environments of the bladder epithelium the urothelium without appropriate models that recapitulate organ biomechanics the emergence of superpathogens is likely to never be counteracted by targeted therapeutic design accelerating antibiotic resistance to greater crisis levels in this msca application i aim to combine my bioengineering experience with the worldleading expertise of my host laboratory in epithelial mechanobiology to create dynamic simulations of human bladderonachip homeostasis and uti infections i will perform thorough analyses on the transcriptomic level of changes across the expanse of the urothelium with periodic filling and voiding during pathogenic and nonpathogenic infections curies will have unparalleled relevance for the drug discovery industry bringing together such advanced methodologies will yield discoveries in molecular mechanisms impacted by bladderpathogen interactions and enable computational modelling simulations to serve as predictive tools by undertaking this work i will develop valuable transferable skills increase my scientific visibility and move closer to scientific independence curies will both shape my academic career and positively impact the fight against antibiotic resistance
surfing radio waves to detect liquid water in the solar system

in the near future a number of space missions will aim to study the icy galilean satellites of jupiter to detect subglacial liquid water using radar sounders to properly interpret the radar data it is necessary to understand the dielectric properties of the icy shells of these bodies as they control radar signal penetration and anomaly ie water detection the current knowledge of these properties for the types of water ices believed to be present is limited which would potentially produce incorrect interpretations of the radar data thus risking the scientific goals of these missions based on extensive experience in characterizing the dielectric properties of planetary analogues which led me and my group to discover the first extraterrestrial subglacial stable body of liquid water on mars we intend to develop new methodologies and protocols to create a groundbreaking knowledgebase that fills this critical gap we will apply the first of its kind methodology for conducting dielectric measurements across a wide range of frequencies including the challenging interval used by these radar systems and temperatures representative of the different iceforming environments produce groundbreaking studies on the structural and chemical behavior of different ice types using ct microtomography and molecular dynamic modelling and will create a wideranging dataset of the dielectric properties of nonterrestrial ices such pioneering and high gain research will allow to obtain the maximum benefit from missions such as juice and europa clipper by the end of the project significant and fundamental progress will be made to properly perform dielectric measurements on icy planetary analogues in the comprehension of the physics behind the dielectric behavior of water ice and icy materials and in radar data modelling and interpretation moreover the projects results will serve as a critical knowledge base for present and future radar sounder planetary missions
west african middle stone age timeline using esr dating of quartz

the evolution of h sapiens in africa is intrinsically linked to the expansion of the middle stone age msa west africa is one of the last frontiers for human evolutionary research and has long been considered to have played virtually no role in our species biological cognitive and behavioural evolution recentlyexcavated msa sites across west african changed this perception but there is still a critical need for reliable chronometric dates to establish a secure timeline for the msa while the optically stimulated luminescence osl dating applied to quartz has already provided some key chronological constraints the method has also shown some clear limitations as it cannot chronologically cover the entire msa time rangewatime project aims to explore the potential of the electron spin resonance esr dating the key alternative method to date quartz the project is built on promising results from a pilot study at bete ianyama site ivory coast which not only demonstrated the potential and feasibility of using titanium ti signals to date quartz samples from west africa but also led to the identification of some specific methodological issues worth investigating further to ensure the reliability of the esr dating method watime will address them by developing and quantifying and measurable accurate criteria to assess the suitability of ti esr signal improving spectral resolution measurement precision and signal characterizationimplementing a new rapid and accurate laboratory esr dating procedure will help resolve the chronology of msa west african sites that cannot be dated by other means watime opens an innovative way to date the key changes in culturalbehavioural patterns from the archaeological record in west africa the results will be broadly communicated through open access and open peer reviewed article resources and targeted public outreach activities
are anthropogenic pollutants in marine sediments a potential methane ch4 source me4sure

current climate change and global warming with a continuous increase of methane ch4 emissions will reshape life on earth oceanic methane emissions are predominantly controlled by the coastal environments which are confronted with intensifying inputs of various anthropogenic chemicals from human activities alarming new correlations have been found between this increased coastal pollution especially discharges from wastewater treatment plants wwtp and ch4 emissions however without knowing the mechanism of influence of the anthropogenic chemicals on ch4 cycle in marine sediments we might be underestimating ch4 into the atmosphere from polluted coastal environments and cannot mitigate these emissions to move from correlationbased observations to a mechanistic and experimentalbased knowledge of ch4 production pathways in polluted coastal sediments it is necessary to apply multidisciplinary approaches in this project it is achieved by a novel strategy through both field and experimental approach where different disciplines compoundspecific isotope analysis biogeochemistry and microbial analysis are applied to provide separate line of to define the level of anthropogenic organic chemicals influence of ch4 emissions in coastal environment i will investigate a representative polluted coastal area located in the swedish west coast which hosts the largest scandinavian oil harbor the primary petrochemical industry in sweden several streams debouch from agricultural areas and the direct discharge of hundreds of chemicals from a wwtp this project is the first step to improve our understanding on how much ch4 is produced in coastal areas affected by chemical pollution with global impact on the ch4 oceanic budget