Dragon09/odtu_chatbot huggingface dataset:
superresolution fieldresolved stimulated raman microscopy

the next generation of biological imaging will be a movement towards superresolution labelfree approaches to visualize subcellular structures in a nonperturbative noninvasive manner in this proposal a superresolution labelfree raman microscope based on a novel ambientair fielddetector is envisioned to fulfil the requirements of these exciting prospects essential for biomedical advancements by employing bright ultrabroadband femtosecond electromagnetic forces at petahertz frequencies raman molecular vibrations are driven coherently and efficiently temporal confinement of the excitation pulses to a few femtoseconds allows for temporal filtering of the molecular response and therefore a high signaltonoise ratio and high detection sensitivity is achieved the same laser provides optical pulses with ultrashort duration to directly access and detects the field oscillations of the emitted raman molecular response this novel detection metrology allows for simultaneous and broadband detection of the entire molecular fingerprint and beyond with high dynamic range and sensitivity down to quantum shot noise most importantly due to the nearfield imaging in this scheme superresolution chemically sensitive images can be constructed without the need for labeling molecules or using structured light the advanced nearinfrared femtosecond source in combination with the novel field detection technology will enable acquiring the complete fingerprint of complex biological molecules noninvasively with a spatial resolution and sensitivity exceeding that of any previously demonstrated method for the first time the next generation of laserdriven biological microscopy requires a dramatic leap in sensitivity dynamic range spatial resolution and noninvasiveness this proposal represents a coherent achievable approach to fulfilling this need opening up new horizons for fundamental studies in science to see beyond the visible
pilot line for european production of perovskitesilicon tandem modules on industrial scale

to prevent the worst outcomes of climate change and increase europes energy independence urgent and massive efforts are required to transform europes energy production to renewable and secure sources photovoltaics pv has emerged as a key technology in these efforts with projected annual growth rates of 3035 over the next years a strong base of pv industry across the entire value chain is therefore of strategic importance for europe to support this strong market growthsince the currently dominating silicon si pv technology is approaching its efficiency limit pepperoni aims to spice up costefficient industrial si cells with a thin perovskite top cell in a monolithic tandem device this technology promises the best ratio of performance over manufacturing costs and therefore enables to push solar module efficiencies beyond the limit of si at lowest co2 footprintthe key objective of pepperoni is to enable largescale production of such tandem pv modules in europe by i demonstrating 26efficient modules on industrial scale ii developing fabrication processes for highvolume manufacturing iii extending the operational stability of tandems to meet market expectations 30 yr and iv removing any human health or environmental riskto reach these objectives pepperoni capitalises on the worldleading tandem pv expertise of a strong and complementary consortium 4 equipment suppliers 2 material suppliers 1 service provider 9 rd institutes and universities that hold tandem efficiency world records and one of the worlds largest pv module manufacturers pepperoni coordinator q cells when joining forces their excellence puts pepperoni in the unique position to set up a tandem pilot line in europe by 2026 this will establish a robust and competitive european innovation base and pv supply chain putting all involved partners well on track towards gwscale production of solar modules in europe by 2030
pregnancy and childbirthrelated media use to support maternal mental health

this interdisciplinary research project is situated on the crossroads of womens health and media psychology the supervisor and the fellow will combine their expertise to study how exposure to pregnancy and childbirthrelated content on the popular social media platform youtube can affect pregnancyrelated anxiety pra we know from the womens health literature that pregnancyrelated anxiety is a serious issue and many pregnant women seek health information online and we know from the media psychology literature that seeking online health information can affect cognitions and behaviors but these two fields of research remain disconnected by bridging the two research fields the scattered research will be systematized and extended we set forth 2 objectives each comprising three research questions to improve our understanding of how pregnancy and childbirthrelated content on youtube can fulfill different needs for women with pra objective 1 and to elucidate the underlying processes of the association between exposure to pregnancy and childbirthrelated content and pra objective 2 to reach our objectives we will use a multimethodological approach in which we combine semistructured interviews work package 1 objective 1 and a longitudinal panel study following a cohort of women throughout their pregnancy wp2 objective 2 the longitudinal panel study will be incorporated in the large scale mobile applicationbased mom2b project currently running at the uppsala university which combines automatically collected digital phenotyping data selfreport questionnaires and objective information from national health registers this project will significantly improve our understanding of how social media can be strategically used by researchers and health workers to improve public health but also of how peers and influencers on social media can informally and often unintentionally play a role in their followers health behaviors and experiences
model transfer and its challenges in science the case of economics

how can a single model be used to study predatorprey interactions in biology the growth of cancer in medicine and the business cycle in economics and how is this practice supposed to contribute to progress in science to answer those questions we need to understand how models are transferred across domains while model transfer is one of the most pertinent phenomena in modern science philosophers have not yet given it due attention our project will fill this lacuna in a groundbreaking way we will provide a comprehensive philosophical investigation of model transfer its challenges and its implications for scientific progress by innovatively combining approaches from philosophy and history of science with computational methods that are themselves new to philosophy because the literature so far neglects model transfer in the social sciences we will focus on economics as an exemplary case that provides insights for the social and natural sciences alike the main objectives of this project are to 1 develop methodological and conceptual tools to study model transfer across scientific domains 2 apply those tools to philosophically investigate model transfer and its challenges in science 3 explore the implications of our results for the relationship between model transfer and scientific progress this project will place model transfer upfront on the philosophical agenda thereby our research will impact an extensive literature on scientific models and modelling in philosophy of science and the social sciences by applying computational methods to study model transfer it will push their use in empirical philosophy of science and integrated history and philosophy of science it will challenge established philosophical concepts of progress in light of such model transfers finally it will inform scientific and science policy debates about how to overcome challenges to model transfer so that progress in modelbased science can be ensured
anodefree liion batteries aflibs investigating electrochemical performance and scalability for nextgeneration energy storage

anodefree lithium batteries aflibs have emerged as a promising alternative to conventional lithiummetal batteries due to their potential for higher energy densities improved safety and simplified manufacturing processes however their rapid development is hindered by poor chargedischarge cycles this is due to the side reactions of the conventional battery electrolytes to form deadinactive lithium thereby leading to dendritic li plating i propose to investigate the use of high concentrated electrolytes hces and multisalt electrolytes mses as novel approaches to achieve a robust and efficient plating and stripping of li in aflibs the high concentration andor presence of additives in these proposed electrolytes can regulate the thermodynamics and kinetics of the li depositionstriping process thereby overcoming dendritic li growth to achieve this objective i will prepare novel hces and mses and use various insitu and operando structural and spectroscopic techniques to gain insights into the effects of the electrolyte types different types of anion and cation and composition on the lithium deposition and formation of sei in aflibs these fundamental insights will facilitate the development of aflibs which are among the nextgeneration advanced energy storage technologies that are pivotal to the realization of energy and environmental sustainability
research initiative for enhancing and adapting workforce skills for implementing transport automation with employment growth

reskilling envisions to implement a strategic approach which will empower the workforce and businesses of europes mobility of people and goods sector to effectively cope with the anticipated changes in the sector from ccam deployment but also to actively participate in advancing and refining the sector for this to be achieved reskilling will propose implement apply and validate a comprehensive approach guided by inclusivity cocreation and social innovation principles which will efficiently and sustainably coordinate a range of novel services and tools fostering optimal adaptation of the mobility sector covering both people and goods to the deployment of ccam solutions and services this will range from analysing the socioeconomic and employment impacts of ccam across the entire value chain to facilitate businesses and workers in mitigating drawbacks and leveraging opportunities brought about by ccam deployment it involves innovating business models and employing mechanisms and training tools for skill enhancement and adaptation with an emphasis on their replication and transferability potential and customized scalability for adoption throughout the eu reskilling aspires to create a ccam innovation system capable of not only generating innovation but also delivering solutions to societal challenges
tailoring organicinorganic layered structures to build functional graded 2d nanomaterials for advanced nanointerfaces

advanced functional devices require integration of distinct materials polymers ceramics metals with different properties to achieve high performance in aerospace biomedicine electronic and automotive a major structural challenge is associated with localized mechanical thermal electrical stresses due to property mismatch at different scales thus causing premature malfunction and failure research has focussed on compositional or structural material gradients in at least one spatial direction to enable fabrication of inone body parts mostly inorganics with exceptional properties examples at rather macroscale include algaas with graded bandgap for solar cells or al2o3ti with graded mechanical stiffness for bioimplants however in light of miniaturization technology there is a need to translate this concept to nanomaterials the eva project aims to establish scientific principles to design and fabricate pioneering organicinorganic 2d layered nanomaterials with functional gradients and continuous interfaces my approach to designing such innovative nanomaterials is based on their compositional engineering by using correlations to perform an extended mapping of combinations and properties i will explore selfassembly techniques in solution and translate them into automated processes to hierarchically build robust components with nmlayered thicknesses and mechanical and optoelectronic gradients eva will also demonstrate their use as advanced interfaces for soft biotissue coupling and flexible lighting nanosystems providing answers from the nanoscale to key drivers in these fields reliability robustness and durability through this interdisciplinary approach physics chemistry mechanics biology and materials science the envisioned atomically designed hybrids will be a hallmark for frontiers in fields such as energy health robotics and digital technologies
regulation of acinetobacter baumannii biofilm formation by cdigmp signaling

in recent years acinetobacter baumannii has been recognized as a serious threat to human health due to its high rates of infection and resistance to various antibiotics both the world health organization who and the centers for disease control and prevention cdc have announced a baumannii as an urgent threat with a priority to find novel antimicrobials against it various diseases have been attributed to biofilms of a baumannii and since biofilms are inherently tolerant to antibiotics the treatment procedures are challenged the nucleotide signaling molecule cdigmp has been shown to regulate biofilm formation in a variety of bacterial species previous studies have shown a role of cdigmp signaling in biofilm formation by a baumannii but the underlying mechanisms still remain unclear understanding the mechanisms of cdigmp signaling systems potentially contribute to identification of new drug targets therefore this research proposal intends to obtain knowledge on how cdigmp signaling regulates key components involved in biofilm formation by a baumannii through a multidisciplinary approach by employing biochemical molecular and microbiological techniques the project is in line with the organization for economic cooperation and development oecd request and eu action on antibacterial resistance the proposed project will establish a research platform based on a baumannii in the host institute the candidate will gain knowledge about cdigmp signaling system and the methods needed to elucidate the function of proteins which are associated with specific microbial traits the acquired techniques along with the transferable skills obtained during the implementation of this project will greatly increase the candidates competency to find a job in positions related to molecular and pharmaceutical microbiology
powder is the only app offering a complete turnkey solution to automatically detect the best gaming moments earn rewards from quests and challenges and compete with other gamers

powder is the only app offering a complete turnkey solution to automatically detect the best gaming moments earn rewards from quests and compete with other gamersas a deep tech company we invest in selfsupervised machine learning techniques for highlight detection surpassing stateoftheartin a market set to surpass three billion gamers by 2023 with steady yearly growth in the last seven years 56 powder brings disruptive innovation to the market by empowering every gamer to become a content creator and socialize with their peers through clips and challenges as their virtual lives get richer and lifestyle gaming becomes a daily activity gamers are increasingly looking for ways to make the most of their meaningful moments in the virtual worldspowder empowers every gamer with a platform that puts the users interests at his core challenging the existing social media models by proudly committing to delivering a stronger fairer more digital and more resilient europe
hipflapp high precision flavoured particle production at the large hadron collider

the project will develop and exploit theoretical calculations to study particle collisions that feature heavy flavours namely the charm quark and beauty quark at the large hadron collider identifying heavy quarks is critical to pinpoint specific scattering processes and reject backgrounds resulting in an unique opportunity to probe the structure of the proton to improve our understanding of the higgs mechanism and to possibly unveil the presence of new physics signals in the lhc data on the theoretical side the accuracy and the precision of phenomenological predictions must be increased to keep up with the progressively smaller uncertainty on experimental measurements so that reliable comparisons with experimental data can be performed more specifically the project will focus on very accurate computations in quantum chromodynamics to better describe the production of flavoured particles across a wide kinematic range so that no region of phasespace is left unexplored these theory predictions will require a combination of both fixedorder and allorder perturbative calculations in the strong coupling constant a public code with the implementation of the predictions for heavy hadron production at ultimate precision will be assembled hence providing other researchers in theoretical physics and the experimental collaborations with a valuable tool in the lhc precision era
evolve where did life originate from and how does it evolve

how did life get started on earth does life exist on other planets how lifethreatening are humaninduced phenomena such as climate change and virus pandemics these existential questions fascinate the general public and concern politicians recent advances in several fields of science have led to partial answers but only an interdisciplinary approach can fully address these questions our previous cofund programme olife has made important advances in understanding the origin and evolution of life and in the course of this exciting 3 year programme we realized that many more steps should be taken we therefore propose a new programme evolve which will appoint 17 doctoral students in biochemistry astrophysics and evolutionary ecology at the worldleading universities of groningen and leiden the students will carry out toplevel research on topics ranging from simulating celllike behaviour in the laboratory to the future evolution of life on earth and the suitability of extrasolar planets to host life besides their research the students will follow a training programme to learn how to interact with scientists from other fields and how to connect science to business and policy they will also learn to follow modern open science practices for maximum impact and to apply diversity inclusion standards to ensure a socially safe research environment secondments at commercial companies nonprofit governmental organisations and academic institutes will prepare them for careers inside and outside academia the evolve programme is committed to the eu green charter for a sustainable future of our planetwe will communicate the results of the program to the scientific community industry policy makers schools and the general public through a variety of targeted media channels
reliable durable high power hydrogen fueled pem fuel cell stack

realhyfc gathers key actors of the whole pemfc value chain to overcome crucial hurdles towards industrial empowerment on heavyduty hd applications mainly for land transport while expecting benefits for ships trains or aircrafts the technical issues precluding a rapid and wide adoption of pemfc on hd applications are linked with reliability and versatility of the stacks realhyfc will bring knowledge and experimental feedback on two key levels stack design and stack operation regarding stack design carbon and metallic technologies will be investigated on efficiency and lifetime issues local degradation and mechanical properties unpreceded direct comparison will be possible thanks to the adaption of an opendesign made for metal to carboncomposite case with developments on bipolar plates and balance of stack realhyfc will eventually deliver a public opendesign platform with demonstrated high efficiency and durability under hd application conditions for longlasting operation the diagnostics and monitoring of stacks are crucial to preclude damages on performance or components realhyfc will bring new solutions based on improved physical degradation models allowing to develop virtual sensors algorithms to optimize fuel cell operating conditions and hybridization strategy final validation by demonstration of lifetime improvements thanks to an adjusted control chain will be done following systemrepresentative simulation and experimental approaches towards durabilityoriented operation in hd environmentthe outcomes of the project are strongly linked with the industrial world and settings carrying relevant pemfc use realhyfc will enable the development of costcompetitive reliable and durable fuel cell technology to this extend an exploitation strategy will foster industrial empowerment alongside dissemination and communication towards technical audience and large public
preferableii personalised exerciseoncology for improvement of supportive care a super umbrella trial to demonstrate the costeffectiveness of liveremote exercise in cancer survivors

with over 12 million cancer survivors relying on supportive care across the eu it is essential to provide them with costeffective interventions tailored to their specific needs many survivors suffer from longterm side effects that can lower their quality of life qol functioning and productivity exercise interventions have proven to be uniquely beneficial in managing both physical and psychological complaints however their effects are strongest when tailored to a patients specific burden eg fatigue low physical fitness anxiety and depressive symptoms or chemotherapyinduced peripheral neuropathy moreover the use of exercise interventions in supportive cancer care is still limited due to a lack of availability a lack of accessibility caused by time and travel constraints and low awareness to tackle these hurdles the preferableii consortium sets out to design and demonstrate the costeffectiveness of a novel exercise intervention that 1 will be tailored to the side effect that bothers the survivor the most by use of a modular design 2 can be implemented at home with liveremote supervision from a national broadcast centre 3 is available to all cancer survivors and 4 incorporates improved patientcentred communication and shared decision making results of our rct enrolling 350 cancer survivors will be translated into guideline recommendations for exerciseoncology extensive ethical legal and social impact components of the project will reveal barriers and facilitators of liveremote supervised exercise and provide policy recommendations to further support implementation finally we will create communication standards and an education module for healthcare professionals to train the future workforce as such preferableii contributes to improving the qol of cancer survivors by lowering the burden of side effects while also improving availability access and awareness off exercisebased supportive care interventions