Dragon09/odtu_chatbot huggingface dataset:
utilization of private land for mainstreaming naturebased solution in the systemic transformation towards a climateresilient europe

land4climate aims to increase the resilience of landscapes and urban settlements in the continental biogeographical area and beyond by nudging the implementation of naturebased solutions nbs which are at largescale still in its infancy however there are three reasons for the tardy uptake of nbs in practice 1 nbs need more land than grey infrastructure 2 approaches to nbs hitherto often focus on public land 3 private land however bears huge potential for climate resilience both as a supplier in terms of ecosystem service provision and a recipient of benefits of nbs in terms of climate risk reduction land4climate addresses these implementation gapsclimate resilience needs land land4climate aims to get access to private land for the implementation of nbs not by buying land but through the development of innovative governance schemes and business models such as land readjustments schemes strategic land leases and easements the main objective of land4climate is to codesign and validate nbs on private land through implementation and upscaling with innovative strategies of land policy for a transformative climateresilient future in areas with multiple risks especially coupled extreme hydrometeorological events such as floods droughts and urban heatland4climate will operationalize this objective in six frontrunner cases in austria czechia germany italy romania and slovakia by identifying cause and effect relations of climate risks and nbs to allocate nbs effectively and efficientlydeveloping governance and business models to implement legitimate and just strategies of land policy for nbs on private land enabling successful replication and upscaling by involving seven replicant regions in the aforementioned countries land4climate becomes able to replicate foster and inspire new synergies between nbs beneficiaries and landowners on a wider scale and contribute to the eus mission for adaptation to climate change
ondas de peniche

the untapped potential of wave energy emerges as a promising horizon projected to reach up to 1800 twh per year in europe however full operational conditions of a wave energy farm are required to improve market confidence and increase the bankability and insurability of wave energy commercial projectsin this context ondep aims at setting up a 2mw farm composed of 4 waveroller units connected to the grid in peniche portugal this will leverage 10 years of experience at this site including two years of fullscale demonstration of the patented and certified waveroller unit 20192021 over five years and a half ondep aims at emulating the needs and technical challenges of future extra largescale wave farms while establishing a complete endtoend european supply chain for gwscale deployment in europe it also includes the first comprehensive environmental analysis spanning several decades for wave energy production ondep is a pathway to scale up wave energy farms in the short term and by 2030 the project expects to unlock 11 farms in 8 countries across 4 continents with a cumulative 83 mw capacity mous and support letters already signed and a gwp 25 gco2eqkwh beyond 2035 the expected lcoe 100mwh will pave the way towards a sustainable blue economy creating up to 500000 jobs in europeto achieve its ambitious goals ondep involves 9 countries and 14 leading organisations covering the whole endtoend value chain of the wave energy sector
on the use of internet of senses for the cultural heritage

creative industries encompass a diverse array of sectors including arts craftsmanship media design advertising software and more current research trends often focus on addressing various challenges and opportunities within these industries one prevalent area of study involves examining the impact of emerging technologies on creative processes particularly in terms of technological advancements and innovation artificial intelligence ai generative ai internet of senses and digital twins dts are key technologies frequently explored in this context by leveraging these technologies within a virtual immersive world there is potential to create an innovative platform that opens up opportunities for novel services in the cultural and creative industries ccis domain ellie aims to support ccis in enhancing their portfolios by providing a universal platform that integrates multiple highimpact technologies like the above and immersive worlds this platform seeks to facilitate the creation of new user experiences simplify the development of creative products and better understand user needs ellies overarching objective is to offer a comprehensive solution that aids in the delivery of advanced services and expedites the production of new products this initiative empowers stakeholders to streamline the workflow of service and product creation through the combination of the above technologies ellie supports innovative and automated processes ultimately providing end users with highquality experiences
regeneration of neighbourhoods through placebased approaches

ginnger will ease the regeneration of neighbourhoods and built environments through the implementation of cocreation processes in heterogeneous stakeholders structures this will facilitate the planification and implementation of actions in local environments leading to a reduction of social environmental technological and economic risks thus to deliver healthy affordable and sustainable built environments in eu the project will create positive social impact in neighbourhoods by stablishing and validating the ginnger cocreation methodology aimed at supporting decisionmaking procedures for regeneration actions the cocreation methodology will rely on ssh innovations for social progress and the enhancement of public policies the project will put special emphasis on the validation of the cocreation methodology in 6 pilots p1 langreo es p2 plovdiv bg p3 massagno in ch p4 murcia es p5 orte it and p6 paris fr within these pilots the cocreation methodology will support the implementation of 21 regeneration actions moreover ginnger will setup a local figure called the green neighbourhood facilitator which will ensure that voices across pilots are heard and will lead the capacity buildings actions at local level to complement the implementation of the regeneration actions from a technical perspective ginnger will develop and validate a digital toolkit to support the planification implementation and operation of the regeneration actions the digital toolkit will be composed by a total of 13 digital solutions grouped into four blocks dealing with energy renovation resources and mobilityas a result ginnger will set longterm strategies for the planification and implementation of cooperative models for neighbourhood regeneration facilitated by the generation of 14 key exploitable results during the project the implementation of such an ambitious project requires of a consortium of 24 partners from 8 ec member states
barents sea arctic cenozoic evolution and paleogeographical reconstructions

this project barents sea arctic cenozoic evolution and paleogeographical reconstructions bravo aims to reconstruct the barents sea gateway since the cenozoic the last 66 myr to do so bravos objectives are to 1 reveal the effect of sediment loadingunloading lithospheric strength and surfacemantle processes on shaping the cenozoic paleobathymetrytopography of barents sea to 2 constrain the timing of the formation of the bsg to 3 identify the interplay between climate dynamics and tectonics in erosion and deposition of sediments in the paleobarents sea and 4 compare the development of the bsg and fram strait as well as the regional to global consequences of the arcticatlantic shallow water connection bravo will achieve these objectives by numerical modelling inc finite element and volumetric methods using opensource platforms of pygplates pybadlands and highresolution 2d3d seismic well gravity and magnetic data analyses bravos results will be selfconsistent 4d earth models space and time of paleobathymetrytopography of barents sea gateway and corresponding sedimentary pathways and accumulation bravos ambition is to provide the most reliable paleobathymetrictopographic reconstruction of the barents sea gateway for the cenozoic bravo will quantify the role of barents sea gateway in exchanging atlanticarctic water highlight the significance of erosiondeposition of sediments in shaping the gateway and form the basis for updated global oceanographic and climatic simulations bravos pioneering model of the complete cenozoic sourcetosink analysis for the regional barents sea will be a breakthrough for arctic seabed characterization for offshore wind turbines and mapping slope failure geohazards
photonic quantum technologies with strainfree artificial atoms

photons are an excellent platform to explore fundamental quantum properties without disturbance from the environment they are also advantageous for applied topics such as quantum communication and simulation the prerequisite for exploiting photons in quantum science is producing and manipulating highquality streams of entangled photons in a scalable setting yet the progress on this front has been slow primarily due to shortcomings in material properties so far only small states involving three photons have been demonstrated and the quest of generating twodimensional entanglement is untouched in this project i will address the scalability problem employing an emerging class of artificial atoms named gallium arsenide quantum dots gaas qds contrary to standard qds gaas qds are free from mechanical strain as a result gaas qds have lower noise and different gaas qds have similar optical properties these are critical requirements for a scalable platform we will use photonic nanostructures to flexibly interface gaas qds on a photonic chip such a scalable platform will be an invaluable contribution to photonic quantum technologies as an immediate outcome we will use this platform to deliver three novel goals1 highly entangled states of photons with twodimensional connectivity2 first experimental studies on the interaction between photons in a strongly nonlinear medium3 pave the way towards quantum memories based on the collective states of nuclei in a qdthese achievements will be enabling contributions to quantum technologies twodimensional clusters of entangled photons are indispensable resources with immediate applications in quantum communication and will open new prospects for photonic quantum simulation additionally studying the interaction between photons in a strongly nonlinear medium will enable us to build numberresolving photon detectors and in the longer term may enable emulating manybody quantum systems on our platform
skill partnerships for sustainable and just migration patterns

this project aims to develop systemic analysis of skills shortages in the 5 eu countries france germany italy poland lithuania and 6 non eu countries turkiye uk norway noth macedonia ukraine ethiopia in the context of the global workforce migration by providing researchbased evidence on the nature and development of skill shortages as well as on the potential of different skills partnerships to tackle these shortages in the countries of origin and destination of migrants there are four main objectives of research serving as a basis for the corresponding workpackages which contain different sets of research questions and activities1 designing of the shortage model for recruitment of skilled workers in the countries of destination 1st group transition countries 2nd group by referring to the agency of existing skill partnerships in these countries 2 evaluation of the labour market in analysing matching needs and shortages of skilled workforce in the countries of origin compared to the countries of destination and transition countries 3 surveying skilled migrant workers in the countries of destination and origin returned migrants this survey seeks to provide the perspective of migrants to the above discussed questions of research 4 analysis of conditions which influence positively or negatively local development processes visvis foreign upskilling and recruitment in the destination countries as well as the conditions which lead to domestic institutions of the origin countries to capitalize on the positive effects of migration for skill development of their population 5 preparing a toolkit for implementation and development fo skill partnerships between the countries of origin and destination in order to enable and facilitate sustainable and fair investments in skills and dealing with the challenges of skill shortages and migration by preventing skill losses and brain drain
glycans as master triggers of health to intestinal inflammation transition

chronic inflammation underlies several diseases in crohns disease cd there is mounting evidence of a preclinical phase characterized by immunological changes that precede symptoms here we propose a thorough and innovative approach to better understand the healthtochronic inflammation transition occurring in patients with cd that will be translated in improved disease prediction and prevention we will address how changes in glycosylation of the gut mucosa act as a primary event that dysregulates not only local mechanisms imposing maladapted hostmicrobiome interactions but also systemic mechanisms promoting antimicrobial antibodies production involving the novel concept of glycan mimicry as an early trigger of the health to inflammation transition glycantrigger capitalizing on our recent findings showing that changes in the expression of complex branched nglycans at gut mucosa regulate inflammatory bowel disease immunopathogenesis we here hypothesize that changes in gut glycocalyx impose early perturbations in hostmicrobiome interactions leading to the exposure of altered glyconeoantigens both by pathogens and host epithelial cells which trigger the activation of innate immune response moreover following our recent discovery that changes in glycosylation can be detected in serum years before cd diagnosis and are correlated with increased levels of pathogenic antimicrobial antibodies asca we will here pursue the hypothesis that changes in mucosa glycans constitute a major source for the development of antiglycan antibodies asca associated with healthtoinflammation transition the longterm goal of this proposal is to unlock through an integrative approach a new checkpoint that regulates the transition to chronic inflammation our proposal will lead to breakthrough concepts in the health to chronic inflammation transition and to novel predictive tools translated in novel glycointervention strategies for disease prevention
trapping and killing glioblastoma

glioblastoma multiformegb is an aggressive brain cancer associated with a 2 5year survival rate and 250000 new diagnoses globallygold standard treatment includes surgical resection and radiotherapy coupled with temozolomidetmz chemotherapy that promote cancer cell deathresistance to tmz and radiotherapy develops rapidly due to dna repair mechanisms indicating that targeted disruption of them can potentiate these therapies trapkill combines cancer mechanobiology microfabrication and biomaterials engineering to develop a pioneering therapeutic trifunctionalised hydrogelphysically modified to present 3d microchannelsand chemically functionalised with gb chemoattractant cxcl12 and tmzthese promote durotaxischemotaxismediated gb cell infiltrationconstraining cells into elongated morphologiesstressing the nucleusdisrupting dna repair mechanismsand rendering cells susceptible to therapies i have shown that 3d patterned hydrogels promote gb gl261 cell infiltrationforcing cells to adopt a filamentous conformation and subjecting the cell nuclei to significant sheartensioncompressive forcesfollowing microchannel sequesteringpreliminary data indicate that cells upregulate stressrelated signalling processes and lose the protective effects of cell agglomerationit is envisaged that trapkill glioblastoma therapy will significantly enhance the efficacy of gold standard chemoradiotherapy approaches trapkill objectives includea chemoattractanttmz functionalised and micropatterned hydrogel to create trapkill therapy analysis of microchannel dimensions on gb cell morphologynuclear stress and cell sensitivity to tmzgamma radiation in vitroassess transcriptome changes in mechanically stressed gb cells and in dna repair gene transcriptionpreclinical resectionradiation murine gb model assessmenttrapkill will create a transformative gb treatmentwith a combined approach to significantly revolutionise existingnextgeneration gb therapies
research infrastructure access in nanoscience nanotechnology

research in the fields of nanoscience and nanotechnology is vital for sustainability globally advancement in nanoscience and nanotechnology cannot be achieved without using research infrastructures ri riana encompasses 7 european networks of toplevel ris to cover the most advanced techniques relevant for synthesis nanofabrication processing characterization analytics as well as simulation capacity highly customised and efficient access to 69 infrastructures is coordinated via a singleentry point and enabled through comprehensive science and innovation service by senior scientists experts for the transfer of technology from academia to industry and highly trained junior scientists the junior scientist boost ri experience to an entirely new level they provide customised science service supporting users from initial ideas to handson experiments data analysis and dissemination of results to generate the greatest impact from access to worldclass ri this core of riana is aligned to attract experienced and new users from academia or industry making their promising ideas a success and push them to higher trl riana is flexible to upcoming emergent scientific topics and needs together with stakeholders from the nanocommunity riana implements the opportunity to offer flexible access to additional infrastructures in and even outside of europe beyond the current consortium and to direct the science service towards evolving user needs via additional specialised junior scientists based on the four years of experience the riana consortium will develop a roadmap for the future of the nanoscience and nanotechnology at european ris
high dimensional probability and combinatorics

this project concerns three related topics concerning high dimensional probability and combinatorics the first part concerns fundamental questions concerning random matrices these include the problem of finding sharp bounds on the singularity probabilities for discrete random matrices and determining the limiting spectral distributions of sparse matrix models the second major goal of this project is to make progress on the hypergraph ramsey numbers and the multicolour ramsey numbers these are two absolutely central objects in combinatorics which remain mysterious in many respects despite many years of intense activity finally i propose to study the chowla cosine problem this is an old problem in the area of harmonic and fourier analysis which the pi has recently been studying through a probabilistic lens
superconducting and ferroelectric twodimensional electron gases 2degs at oxide interfaces

in the project surfer we will demonstrate the coexistence of antagonistic properties namely superconductivity sc and ferroelectricity fe and the enhancement of superconducting transition temperature tc through coupling with fe in oxide twodimensional electron gases 2degs so far this coupling has almost only been observed in bulk oxides and in thin films of doped srtio3 sto where no ferroelectric switching is possible due to the threedimensional distribution of carriers the origin of sc and enhanced tc due to coupling between fe and sc is still not clarified which might be because only one material sto system has been studied in surfer we aim to realize ferroelectric and superconducting oxide 2degs with enhanced superconducting properties that are also switchable with fe present in these systems with this aim we will explore three new oxide 2deg systems that have not been studied so far which will be fabricated based on different ferroelectric materials 1 sto thin films 2 batio3 and 3 niobium nbsubstituted ktao3 by growing on top a thin metal or oxide overlayer in addition to the experimental realization of oxide 2degs hosting such interesting properties this project will also help us to gain a clear understanding about the origin of sc and enhanced tc due to fe and sc coupling in oxides which is a longstanding question by investigating the properties of these material systems in detail
defining clinical and molecular phenotypes of multidrug resistance in difficult to treat rheumatoid arthritis

rheumatoid arthritis ra is the most common chronic inflammatory joint disease with a prevalence of about 1 of the adult population 22m patients worldwide and 7m in eu and estimated to be responsible for 10000 disability adjusted life years dalys costing eu society 55b annually despite aggressive therapy about a third of patients have to give up work within 5 years of disease onset mainly due to lack of response to multiple disease modifying antirheumatic drugs dmards multidrug resistance mdr thus the main objective of this proposal is to define the clinical and molecular phenotypes leading to mdr in ra patients to prevent when possible or when not possible optimise the management of these patients mdrra is highly relevant to the program as these patients are often disabled unable to work and paying a high personal and societal burden moreover mdrra is underresearched and the underlying pathobiological mechanisms for resistance remain unknown while as we have no predictors of therapeutic response to any of currently available drugs inevitably treatment is based on trialanderror mdrra has the ambition of transforming care for these patients and deliver significant advances beyond the stateoftheart methodologies as for the first time molecular pathology will be integrated into clinical psychosocial pain perception and imaging profiling in existing clinical cohorts to develop truly holistic predictive models for future clinical use icarera the transformative potential of icarera will be tested in a prospective randomised trial in comparison with routine standard of care while its future implementation potential will be assessed through an early economic modelling finally a strong management and dissemination strategy will facilitate further advancing science in the field beyond the duration of the project and future adoption by patients specialist professional bodies policy makers and regulatory authorities