Dragon09/odtu_chatbot huggingface dataset:
overcoming hurdles to the diffusion of environmentally sustainable behaviour

the need for action on tackling climate change has reached a makeorbreak moment we can only deliver on the commitments made in the paris agreement if we act now given the importance of consumer behaviour in addressing climate change and the urgency for action accelerating the growth in the adoption of green practices is critical if europe is to become a climate neutral continent by 2050 however while the availability and consumption of sustainable product and service options has been growing the diffusion of these sustainable practices in society has been slow showing that early adoption of sustainable consumption practices does not sufficiently generalize to similar practices or other consumers the overarching objective of this project is to study why instances of environmentally sustainable behaviour does not always invite more instances of such behaviour i will study the hurdles first at the intrapersonal level by looking at downstream consequences of perceptual biases and testing intrapersonal consistency across different consumer domains then i will move to the interpersonal level studying barriers that might prevent consumers from following or mimicking the green behaviour of others at both levels i will test a number of theoretically justifiable remedies and nudges to correct for these biases the project findings will provide valuable input in defining policy and strategies to encourage environmentally sustainable consumption and will help consumers in interpreting ecoinformation and understanding the effects of biases on their own consumer behaviour
cognition and neurocomputations of motivation and planning

being able to make adaptive decisions and follow through is crucial for animals and humans alike while some simplifications of real life environments are necessary for laboratory settings past studies have often removed essential complexity specifically a common reductionist approach toward decision making focuses exclusively on a neuroeconomic framing however this neglects that in the real world behaviour is often a sequence of choices requiring planning and sustained motivation to reach our goals only by examining cognition and behaviour embedded in these sequences can we gain a full understanding of prefrontal cortex function in general and its cognitive computational and neural role in sequential behaviours in particular to answer this challenge over the last couple of years i have been at the forefront of developing a new neuroethological approach enabled by advances in computational modeling experimental designs brain recording annd stimulation techniques in the proposal i have identified key cognitive processes linked to challenges the prefrontal cortex has evolved to solve for prefrontal cortex this means sequential and selfdetermined behaviours to make the complexity tractable i take inspiration from multiple disciplines including ecology biology psychology and neuroscience this way i can identify the essential elements for achieving adaptive complex behaviour as a response to reallife challenges and build unifying computational models around those processes
fast tracking the conversion of dual fuel engines in existing offshore vessels to ammonia operation

the apollo project will mature and demonstrate in operational environment the disruptive installation of a dual fuel ammonia engine in an offshore supply vessel to ammonia operation reducing emissions by 70 the project is developed to closely answer the horizoncl52022d50104 topic of transformation of the existing fleet towards greener operations through retrofitting zewt partnership the specific objectives include 1 successful largescale demonstration of the use of dualfuel ice ammoniabased in an existing vessel 2 complete first classification under dnv gas fuelled ammonia 3 70 reduction of co2 emissions and nox emissions below 24 gkwh from vessel operations 4 complete retrofitting solution to operate on ammonia through development of safe ammonia storage and operation including both deck load or below deck tanks 5 demonstrate the retrofit in replicators in other two vessels with different use dredging and offshore construction and validate feasibility for scaling 6 support to the expansion of the ammonia bunkering network in the north sea and beyond obtain 100 green ammonia for the projects needs 7 validated business case for ammonia as a ship fuel with operational expenditures 130 from baseline by project end the apollo solution will be flexible so ship owners ship designers shipyards classification agencies and insurance companies can quickly adopt it into their decisionmaking processes the consortium will prepare the business case for ammonia in the waterborne transport sector from the production of green ammonia to its use in different ships on the european scale
european city squared computational social science simulation for democracy

in response to the urgent challenges facing modern democracies the european city squared project will use real and synthetic data along with the latest advances in quantum and classical computational social science to develop an agentbased computer simulation environment that integrates recent advances in science and technology with social choice theory this interdisciplinary approach involving leading scientists city governments universities entrepreneurs and civil society representatives will explore the effectiveness of various voting mechanisms with a primary focus on quadratic voting this novel method of voting has potential to enhance public good allocation and foster an emergent and natural altruism addressing concerns such as polarization and trust in governmentour methodology will be underpinned by a rigorous adherence to data protection standards ensuring gdpr compliance and the ethical integrity of our research by employing mathematical models inspired by natural phenomena we will identify algorithms conducive to robust democratic decisionmaking these algorithms will be tested in realworld scenarios in collaboration with our government partners particularly the city of aarhus denmarkthe project aims to not only provide groundbreaking insights into democratic governance but also to contribute practical tools for enhancing efficiency and participation in democratic processes if successful our research promises to offer significant contributions to the fields of political science computational modeling and social choice theory with the potential to bring unprecedented efficiency gains for european democracies
sub sea quieter a disruptive low cost and highly efficient noise mitigation system for reducing mre installation noise and turbidity impacts on underwater ecosystems

for offshore windfarms or coastal foundations pile driving technique is often used but it generates a high level of noise which severly damages up to death marine mammals fishes and other species noise mitigation systems nms exist but with limits high price weak acoustic efficiency bad behavior with current waves and depthto fill these gaps we develop an innovative and ecodesigned nms the ssq pile drivingit is based on the disruptive membrane sub sea quieter inflatable panels of 3dwoven fabric coated and sealed to insure acoustic efficiency resulting from 5 years of rddesigned like a sock deployed closest and around the pile thanks to a clever manutention system it aims at becoming the nms technical reference by its very high acoustic mitigation efficiency turbidity containment its cost up to 5 to 10 times cheaper than existing nms with no any extra vessel or crane and its adaptability to the most severe site conditions waves curent depth
towards a sustainable wellbeing economy integrated policies and transformative indicators

tobe aims to build an understanding of a sustainable wellbeing economy by developing integrated policies and transformative indicators we contribute to theoretical and empirical knowledge in the field of sustainability transformation and advance understanding of sustainable wellbeing and inclusive economy beyond gdp together with researchers policymakers and citizens in europe africa and south america we study how mindsets indicators innovations and policies could better work together towards the sustainability paradigmwe bring together green growth and postgrowth initiatives to create a novel understanding of economic growth we also consider environmental and social justice when conceptualising sustainable wellbeing and identifying transformative indicators of a sustainable wellbeing economy we provide new empirical knowledge on economic development social outcomes and sustainability to address entangled societal challenges and to envision integrated policy solutions all this contributes to an ecological macroeconomic model assessing integrated policy packages and to a synthesis typology of an accelerating sustainability paradigmtobes societal impact is linked directly to europes policy goal of becoming a carbonneutral continent by 2050 we will improve policy making capacity and coherence by exploring social and economic resilience and sustainability as well as integrating different policies towards this end the results will help create a sustainable and inclusive economy as well as a shared vision for euafrica relations that build on sustainable growth our cocreation platform will strengthen epistemic communities to drive carbonneutrality and tackle inequality and vulnerability in the context of entangled crises by a better understanding of tradeoffs and synergies between economic growth and a sustainable wellbeing economy including logics of change across different dimensions of sustainable development
whole brain visualisation of the neuroinflammatory response during acute neurotropic flavivirus infection and its implications for virusinduced neurodegeneration

neurotropic flaviviruses such as tickborne encephalitis virus tbev japanese encephalitis virus jev west nile virus wnv and zika virus zikv can enter and infect the central nervous system potentially leading to lethal encephalitis furthermore survivors often suffer from chronic neurological complications most likely due to virusinduced neuronal death and immunerelated pathology the past decade the notion that neurotropic virus infections cause changes to specific neuronal populations driving accelerated brain ageing and neurodegeneration has become an emerging concept however the interplay between virus infection inflammation neuronal death and neurodegeneration remains unravelled in this project i propose to investigate virusinduced neuroinflammation and its effect on pathways underlying neurodegeneration with frontline imaging techniques to do so i will optimise ex vivo optical projection tomography opt and positron emission tomography pet for neuroinflammation and tau tangles and develop accurate imagebased quantification pipelines for the proposed markers these will thereafter be applied to study the neuroinflammatory course in acute flavivirus infection and to unravel the specific role of the microglia in infection and neuroinflammation finally i will investigate the effect of infection and virusinduced neuroinflammation on induction of neurodegeneration reflected the induction of tauopathy taken together this project will lead to the development of advanced ex vivo imaging techniques to visualise neuroinflammation and virusinduced neurodegeneration and will improve our understanding on how neurotropic flaviviruses drive the brain into accelerated ageing thereby priming neurodegeneration
battery 2030 csa3 largescale research initiative at the heart of a connected green society

collaborative longterm research on future battery technologies has since 2019 been supported by the european commission with the battery 2030 initiative this project battery 2030 csa3 builds on earlier csa efforts to coordinate and monitor research projects earmarked battery 2030 to work together towards the goals in the battery 2030 roadmap other he ri projects are invited as associated the overall aim of the battery 2030 initiative is to invent the batteries of the future by providing breakthrough technologies to the european battery industry across the full value chain to strengthen longterm european leadership in both existing markets road transport stationary energy storage and future emerging applications aerospace medical devices internet of things in this third phase accelerated materials discovery battery interfaces smart functionalities manufacturing and recycling are covered battery 2030 csa3 builds on and extends beyond the earlier achievements of the battery 2030 initiative with five objectives obj 1 implementation and monitoring of the research activities contributing to the battery 2030 initiative obj 2 update and develop the battery 2030 roadmap by mapping ongoing ri activities and identifying emerging obstacles and research needs obj 3 accelerate the research by identifying and making available best practices and guidelines for ontology development data sharing and standardizations obj 4 contribute to european curricula in future battery technologies obj 5 promote and communicate the objectives and the achievements of the battery 2030 initiative and strengthen collaboration with other eu ri battery initiatives the csa3 consortium consists of 19 leading european universities and research institutes uu ait cea cic energigune cidetec cnrslrcs dtu empa enea fraunhofer fzj kit wwu nic polito sintef tu delft vub and wtu and 4 associations recharge ease emiri and vdivdet
intrinsic autophagy receptors identity and cellular mechanisms

macromolecular complexes mc are cellular machines that perform a wide array of vital tasks they operate in a controlled coordinated fashion within the crowded environment of the cell accumulation of dysfunctional mcs leads to agerelated diseases despite recent technological advancements it still remains elusive for many of them how excess or dysfunctional mcs are sensed and removed i have recently established a role of intrinsic receptors in degradation of the nuclear pore complex and the clathrinmediated endocytosis machinery by selective autophagy intrinsic receptors represent functional subunits of the macromolecular machine but can if needed recruit the autophagy machinery to engulf and degrade the complex as such intrinsic receptors provide an inbuilt quality control function that monitors the assembly state andor functionality of macromolecular machines i hypothesize that this is a conserved and widely used principle existing within various mcs and that there is a common yet unexplored regulatory pathway underlying the intrinsic receptors mode of action in the proposed project i will employ a combination of genetic screening mass spectrometry and cryoelectron tomography to systematically define intrinsic receptors and their working principles in cells i will use systematic discovery approaches to determine how many mcs contain intrinsic receptors how the degradation of intrinsic receptors and their cargo is regulated and how this is orchestrated with autophagosome biogenesis my results will not only provide insights into a novel cellular qualitycontrol mechanism but also unravel novel aspects of selective autophagosome biogenesis importantly both accumulation of dysfunctional complexes and impairment of autophagy are linked to aging and agerelated diseases therefore my results will contribute to understand the role of autophagy in these processes and have the potential to provide new pharmacological therapeutic avenues
revolutionary silkbased bioink for 3d printing of ex vivo bone marrow models to advance drug development and personalized medicine

aim the silkink project aims to develop a breakthrough biocompatible hydrogel ie a bioink to 3d print bone marrow tissue models that can be used for robust culture of human stem cells the use of silk as the basis for novel bioinks silkink helps to recreate tailored bone marrowlike microenvironments that will enable new applications in drug development and personalized medicine for bone marrow diseases here we aim to optimize and validate silkink further define the business opportunity and found an investmentready spinoff company to commercialize silkinkunmet need bone marrow stem cells are fragile and require highly specific surroundings to survive and differentiate therefore the presence of a soft tissue environment mimicking the human bone marrow is critical for reproducible culturing of these cells there is a large unmet need for reproducible solutions that mimic the soft tissue of the bone marrow to allow advancements in drug development and personalized medicine approaches for bone marrow diseasessolution we will develop silkink a revolutionary bioink that is uniquely based on silk to closely mimic the 3d soft tissue environment of the bone marrow silkink will provide a matrix that supports all bone marrow cells including hematopoietic stem and progenitor cells and allows to 3d print ex vivo bone marrow stem cell models in the shape or volume desiredconsortium university of pavia unipv and partner cellink have developed the silkink prototype during fet open project silkfusion and coown the background ip partner catalyzegroup venture building team cat will bring commercial expertise to develop an optimal market access strategy for silkink unipv will be responsible for silkink optimization manufacturing and validation cellink will be involved in product optimization and responsible for product development cat will assist unipv with founding a spinoff company to commercialize silkink and making it investmentready
business case assessment for biocoal market uptake

the proposed booster grant aims to expand the application of biocoal produced in the h2steel project beyond steelmaking to include cement manufacturing potentially offering higher added value and significant carbon footprint savings a comprehensive market analysis technical and economic feasibility studies and the development of a business case for biocoal in various industrial sectors are essential components of the proposalkey activities include assessing the technical viability and market demand for biocoal identifying strategic industrial contacts and analyzing the impact of the european trading scheme on target industries record leveraging its expertise and established infrastructure will lead the assessment and experimental tasks ensuring the projects alignment with eu sustainability mandatesthe work package structure covers market assessment strategy definition and business case development these will involve evaluating market dynamics competitive landscape financial viability and operational strategies for biocoal introduction the ultimate goal is to convince funding evaluators of the necessity to support the project for achieving a sustainable profitable market rollout of biocoal thereby extending the environmental and economic impacts of the h2steel innovations
the strongaya initiative improving the future of young adults with cancer

strongaya is a new interdisciplinary multistakeholder european network to improve healthcare services research and outcomes for adolescents and young adults aya with cancer defined as individuals aged 1539 years at cancer diagnosis ayas with cancer form a unique group they face agespecific issues eg infertility unemployment financial problems and decreased quality of life due to cancer and its treatment unlike dedicated healthcare and trials for pediatric cancer patients ayaspecific healthcare services are scarce and vary across europe ayas who are at the core of society and economy need access to ageadjusted and highquality healthcare ayacare and research will benefit from collection and pooling of patientcentered data and collaboration among all stakeholders patients healthcare professionals scientists and policymakers our consortium of clinical and scientific leaders in ayacare data science and registries european cancer organisation youth cancer europe and eortc will build on previous initiatives and eu grants within strongaya we will set up a valuebased healthcare research ecosystem to develop datadriven interactive policy and visualization tools that bring in cocreation with all stakeholders including patients novel insights into aya healthcare the project objectives include 1 development of a core outcome set cos for ayas with cancer 2 implementation of the cos in 5 national healthcare systems fr it nl uk pl and establish national infrastructures for outcome data management and clinical decisionmaking and a paneuropean ecosystem that also welcomes future european countries 3 disseminate outcomes and facilitate interactions between national and paneuropean stakeholders to develop datadriven analysis tools to process and present relevant outcomes establish feedback loops for aya cancer patients and the healthcare systems and improve the reporting and assessment of outputs towards policymakers
microbial extracellular polymeric substances basedtechnology for selenium removal from drinking and wastewater using cstr and uasb reactors

selenium se is a naturally occurring trace element in the earths crust microorganisms and their metabolites such as extracellular polymeric substances eps play a major role in the redox transformation of metalloids in the environment however how eps affects se oxyanions redox cycling in drinking water and wastewater what the underlying mechanisms especially electron transfer mechanisms between eps and se and which components of eps are involved in se redox transformation are unclear especially concerning electron transfer mechanisms between epsse oxyanions to form biosenps and which redoxactive components of eps are involved in the redox cycling of se oxyanions how epsmediated reduction of se affects the isotopic fractions of se during the reduction process to what extent do these pure cultures strainderived epsse oxyanions reduction mechanisms apply to the continuous stirred tank reactor cstr and an upflow anaerobic sludge blanket uasb reactor system for water and wastewater treatment respectively in this research we plan to set up in situ and in vitro microcosms combined with electrochemical and spectroscopic techniques to examine 1 the key agents and structural components of eps involved in the reduction of seivvi 2 the electron transfer mechanisms between eps and se oxyanions for the reduction of seivvi 3 the significance of the se reduction to the environmental fate and recovery of biosenps in cstr and uasb reactor the roles of epsmediated reduction processes on the isotopic fractions of se the results from this project will be vital to clarifying the role of microbial eps and their components in the biosenps cycle and developing biotechnologies to remediate and recover environmental se