Dragon09/odtu_chatbot huggingface dataset:
bringing financial support to innovation and portfolio activities increasing impact of eicsupported research

boost project aims to ease the access of eic awardees mainly eic pathfinder and eic transition projects as well as related third parties to the eic booster grants boost project will distribute eic booster grants lumpsum grants to finance innovation and portfolio activities to at least 100 invited eic awardees the booster grant projects will receive up to 50000 following a firstcome firstserved schema boost project will also provide the eic and eismea with data relevant to assessing the impact of such support boost project will do this by guaranteeing efficient and ecrules compliant governance adequate integration of eic booster grants within the eic community support and eiceismea portfolio management activities and gathering operative and impact data that will support evidencebased decisionmaking by the eic and eismeato ensure effective task execution and maximize available resources boost project utilizes a compact and agile consortium this allows up to 83 of the total budget to be allocated to eic awardees the consortium includes spl entity specialised in cascade funding as call for proposals manager mwcb especialised in tech transfer as booster grant projects manager eura pt as monitoring and impact manager all of them coordinated by fba as project coordinator and fstp manager this streamlined consortium will rely on a highquality curated database of over 820 experts who regularly collaborate with the partners to support the evaluation and assessment of booster grant projects all this ensuring a seamless connection with eic procedures and practices as all partners are actively involved in eic projects
novel concept of a low cost high power density and highly efficient recyclable motor for next generation mass produced electric vehicles

heft considers that an energy efficient rareearth synchronous motor is the best option for next generation highpower primary axle traction evs and proposes a set of innovation challenges on electric synchronous motor configuration based on sic inverters direct cooling of rotor and stator advance insulation for high voltage multibarrier rotor topology wave windings and advanced materials advanced gbd magnets epoxy for magnet fixation composite for motor housing insulation resinthese innovations will result in a highefficient and lowcost solution that will be validated on 2 motor topologies which compared to two main reference automotive ipm commercial motors in europe vw id3 and fiat500 will lead to next impacts 800v 20 reduction losses 7 kwkg and 42kwl power density 28 cheaper 5066 material savings including 60 reduction of ree content and 80 ree recyclability rateas this solution is still dependent on ree from china heft will be aligned with the erma action plan towards a circular economy market of rare earth permanent magnets and suggests one alternative magnet route ce based and two ree recycled routes together with policies promotion towards the foundation of a european rare earths industry capable of delivering 20 of eu demand by 2030heft plans 8 wps to implement these concepts where 5 research partners will be essential for developing innovative ideas around the designtox approach while strong companies gkn magneti vyncolit will ensure that heft results have a clear market orientation and fulfil the industry needsheft plans to organise oem workshops to ensure wide adoption of heft solutions but also with policymakers to promote regulations towards the eu circular market that would help maintaining the leadership of eu companies while increasing their competitiveness and job opportunities linked to the new circular business models
tunnel ionization in threedimensional tailored light fields

tunneling is a nonresonant quantum mechanical process without any classical analog the electric field of a strong laser pulse can bend atomic and molecular potentials such that an electron can be liberated via tunneling this allows for probing properties of atomic and molecular orbitals with subnanometer and attosecond resolution like a tunneling microscopes tip probes properties of the investigated surface so far the electric field vector is restricted to a onedimensional line 1d eg linearly polarized light or a twodimensional plane 2d eg circularly polarized light since tunneling acts like a filter to the same 1d or 2d subspace in position space this limits the sensitivity to the 3d structure of the probed orbital i propose to build an experimental setup that can synthesize 3dimensional 3d light fields with peak intensities of up to 1015 wcm2 3d light fields will significantly increase the sensitivity of strong field tunneling to the 3d properties of the bound electronic wave function further nonadiabatic dynamics during tunneling and subsequent acceleration recollision or recapture of the electronic wave packet will be driven by the timedependent 3d field as well this will eg allow for the creation of chiral electron distributions in atoms ie chiral atoms selectively tunnel ionize one enantiomer of a racemic mixture of chiral molecules and enable a new type of pumpprobe experiments the capability to generate 3d light fields will be matched with a 3d detection system which measures 3d electron momenta in coincidence with ionic fragments my team and i will use this novel 3dlight3ddetectionplatform to investigate tunnel ionization from atoms diatomic molecules and chiral molecules i anticipate that the proposed experiments will give rise to a new class of experiments on lightmatter interaction and provide groundbreaking insight regarding the quantum mechanical process of tunneling itself
reading dna in real time for medical applications

the aim of this project is to use an ultrafast high throughput method for analysing dna single molecules for liquid biopsy and other biomedical applications the proposed methodology laserassisted dna optical mapping ladom allows retrieving the barcode of single molecules of dna in real time as they flow through a nanochannel in a fluidic device it combines a cheap device fabrication flexible dna labelling customizable for different applications microscope and camerafree set up a readout sensitive to single molecules very high throughput tens of molecules per minute ability to detect very small fragments and no limitation for the maximum molecules length what is especially interesting for applications dealing with ultralong intact genomic dna in this project we request funding to offer a service to analyze samples from possible stakeholders from the biomedical sector and to standardize the technology and improve the troughput bthe aim of this project is to use an ultrafast high throughput method for analysing dna single molecules for liquid biopsy and other biomedical applications the proposed methodology laserassisted dna optical mapping ladom allows retrieving the barcode of single molecules of dna in real time as they flow through a nanochannel in a fluidic device it combines a cheap device fabrication flexible dna labelling customizable for different applications microscope and camerafree set up a readout sensitive to single molecules very high throughput tens of molecules per minute ability to detect very small fragments and no limitation for the maximum molecules length what is especially interesting for applications dealing with ultralong intact genomic dna in this project we request funding to offer a service to analyze samples from possible stakeholders from the biomedical sector and to standardize the technology and improve the troughput by developing a software to automate the data analysis
dissecting the molecular mechanisms of transgenerational epigenetic inheritance

small rnas have a remarkable regulatory role in most eukaryotes these molecules bind to argonaute proteins ago and form a complex that recognizes its mrna targets by sequence complementarity the regulatory role is driven by the catalytic activity of ago but not exclusively in several organisms ago recruits other factors to perform the silencing remarkably during transcriptional gene silencing the small rnaago complex engages factors that interfere with transcription but also proteins that modify the dna and the chromatin at the targeted loci this phenomenon has been observed in plants yeast flies and worms particularly in the nematode caenorhabditis elegans this silencing regulation can be triggered and inherited by the next generations this reveals the importance of small rnas and chromatin modifications for transmitting nongenetic information and maintaining germline stability across generationsseveral factors required for epigenetic inheritance have been identified by genetic screens in the worms the nuclear argonaute hrde1 is expressed in the gonad and is a key component of this pathway still what are the hrde1associated factors required for transgenerational transcriptional silencing are not fully understood this proposal aims to address what are the factors participating in the different stages of silencing mediated by hrde1 establishment inheritance and maintenance to answer these questions i will employ strains that allow the inducible depletion of the factors involved in the silencing response i will combine these tools with encompassing genomics and proteomic approaches to investigate the changes across generations this proposal will unveil the molecular mechanisms of transgenerational epigenetic inheritance moreover this study will be instrumental for the study of these responses in other organisms especially other nematodes with potential applications to health and ecology
detecting the worlds most accurate field boundaries

digifarm detects the worlds most accurate field boundaries and seeded acres to power precision agriculture leveraging the latest advancements in artificial intelligence technology and superresolution of satellite data our object detection algorithm achieves higher accuracy than the human eye resulting in 1215 higher accuracy than existing solutions
understanding the language of life identifying and characterizing the language units in protein sequences

proteins play a key role in biological processes that govern and maintain life although they are threedimensional entities they can be represented in textual form as sequences of amino acids that largely determine their structures and functions by analogy with natural human languages we can consider proteins as written with a language which we refer to in this proposal as the language of life natural languages can be read and understood by humans however we cannot yet understand the language of life we do not even know what the vocabulary is ie what the basic language units are analogous to words in human languages textual representation of proteins has enabled the application of natural language processing nlp techniques to the study of proteins and breakthrough results have been achieved in various downstream tasks such as protein structure prediction however these efforts remain only at the processing level of the language of life the main goal of this project is to go beyond the level of language processing and open new research horizons for understanding the language of life using my expertise in nlp and bioinformatics i will pursue the following objectives i develop innovative methods to determine the language units ie the vocabulary of the language of life
addressing priorities of evaluated nuclear data in europe

the conception development optimization and safety evaluation of a broad range of nuclear energy fission and fusion and nonenergy applications radiation protection radionuclide production health geosciences space research security and industry require reliable and accurate simulation tools such tools critically rely on accurate nuclear decay and reaction data aprende has the ambition to improve nuclear data for modelling and simulation ms tools used by european stakeholders in the application areas of the european union and its member states that currently have the highest priority the priority application areas identified by stakeholders of nuclear data and by national european and international projects and consultations area all aspects of spent nuclear fuel snfb reactor operational characteristics such as reactivity versus burnup transients and marginsc advanced reactor and fuel cycle development including small modular reactors smr and geniv systems based on lead and sodium coolants molten salts or an accelerator like myrrhad criticality safety and shielding for safety assessments and safety assessment methodologiese nonenergy applications radiation protectionthis ambition requires a comprehensive approach involving the eight objectives stated above and a methodology and impact pathway as detailed below the combination of this ambition objectives methodology and our pathway to create impact is what the proposers believe to be not only the best but also an excellent response to the horizoneuratom2023nrt0106 call improved nuclear data for the safety of energy and nonenergy applications of ionising radiation in the following we break down and explain our ambition by each of the priority application areas
a quantitative risk assessment for fragmental rockfall

climate trends indicate that rockfall events due to global warming effects are expected to increase underlining the urgency for accurate rockfall risk assessment public administrations and private owners often face difficulties in defining risk management plans priority of interventions and allocating resources for mitigation worksridetherisk project aims at improving the knowledge and predictability of rockfall hazard and its consequences in mountain environment and open pit mines it will develop a new physicallybased method to simulate rockfall propagation accounting for rock block fragmentation and to quantify the damages in different contexts civil and mining to fill a knowledge gap in understanding and modelling fragmentation and its effects increasing awareness of its destructive potential the 3 projects objectives are1enhancing rockfall hazard prediction defining analytical solutions to predict fragmentation and implementing a physicalbased trajectory model for fragmental rockfall 2developing a fully timeintegrated quantitative risk assessment method qra for fragmental rockfall able to quantify social and economic damages on both viable infrastructures and open pit mine activities 3promoting the use of the developed qra method turning theory into practice applying it in two real contexts and realizing technical guidelines for experts proposing their adoption to policymakers and activity owners to properly manage the riskthe proposed method at present missing that quantifies the risk in terms of annual probability of death and delayinterruption time for traffic and working activities ie accounting for social and economic aspects respectively will undoubtedly help to face effectively and efficiently rockfall risk dissemination exploitation and communication are thus fundamental these objectives address the challenges of both the european climate pact and the european action plan on critical raw materials
information frictions in hiring decisions

over the last decades internet has sped up and increased interactions between employers and workers but aggregate unemployment does not seem to have been much impacted by this revolution this could be because information frictions are not a firstorder contributor of unemployment or because current tools and institutions do not enable truthful and effective communication between firms and workers employers who are often on the short side of the market find it difficult and costly to screen potential employees inashi aims to provide theoretical frameworks and new empirical evidence about what the remaining information imperfections on the labour market are how important they are to aggregate unemployment and unemployment of the most vulnerable segments of the labour market and what solutions can be put in place to improve the recruiting process inashi will combine novel data on how firms search for workers on large online job boards with administrative data on vacancies and matched employeremployee data it will also leverage a series of randomised controlled trials to test how the provision of new information to employers whether about candidates or about features of the market help them make better hiring decisions leading ultimately to higher aggregate hiring and higherquality matches three countries will be studied austria france and sweden so that inashi will provide evidence valid in a variety of contexts
pervasive gas sensing using optical fibers as part of the communication network of the future

using fibre sensor networks distributed information can be gathered even from places that are difficult or even impossible to be reached by other means however so far such distributed fibre sensing networks are not capable of providing access to distributed chemical information along the fibre in particular highly selective and sensitive information on the concentration of various gases along the fibre cannot be obtained on a routine basis despite being desirable and needed in many different application scenarios it is therefore tempting to explore the potential of integrating innovative optical gas sensing nodes along optical fibres towards their massive deployment in existing telecom infrastructures new developments in optical gas spectroscopy have opened up new prospects for remote gas sensing applications addressing the limitations of current analytical methods in terms of sensitivity easeofuse and miniaturization nevertheless there are important challenges to overcome before such a joint use of the fibers network for both communication and gas sensing becomes possiblegaspof addresses these challenges contributing to the development of the optical infrastructure of the future where the communications network also acts as a largescale distributed multiparameter sensor focus will be put on two different optical techniques for gas sensing using the fiberoptics network laserbased pts and lhr both techniques will be advanced and integrated with the existing optical fibers network infrastructure in parallel we will investigate the possibility of using coherent otdr for distributed gas sensing while a reducedcost approach for acoustic sensing will also be designed for measuring physical parameters of interest eg vibrations in addition to gas sensing the gaspof system configurations will demonstrate their performance and capabilities in important 4 application use cases
a doubleedged sword extragalactic fast xray transients

we will use extragalactic fast xray transients fxts to study binary neutron star bns mergers merging neutron stars are important for the formation of rprocess elements and provide standardizable signals allowing the hubble constant h0 to be measured maximizing the science output of these multimessenger events comparing bns mergers with and without an fxt signal provides a way to constrain the elusive equation of state of matter at supranuclear densities unlike the highly beamed short gammaray burst signal associated with bns mergers the fxt signal is isotropic providing us with the means to quickly localise the merger even for events out to the bns merger detection horizon of the 3rd generation of gw detectors such as einstein telescope or cosmic explorer a highrisk aspect is that the link between fxts and bnss is not yet 100 certain fxts manifest as singular short flashes of xray photons with durations ranging from minutes to hours the imminent launch of the allsky xray survey satellite einstein probe together with the recent deployment of premiere groundbased instrumentation will revolutionize this field by enabling the discovery and immediate followup of a statistically significant sample of more than a hundred bright fxts over the 3yr einstein probe mission duration complemented with a comprehensive study of the fxt host galaxies this will lead to a breakthrough in our understanding of fxts and enabling us to measure the yield of rprocess elements h0 and the maximum mass of a neutron star using bns mergers in addition to our main goals we expect serendipitous discoveries in this new research field
philology as science in 19thcentury europe

philology once defined what it meant to be scientific and it may yet once again increasingly a broad array of scholars using digital methods cite the historical accomplishments of philology as a model for systematic study around unwieldy and heterogenous textual corpuses despite this renewed interest there is still no systemic account for the huge range of activity and aegis data and networks that propelled philology to its status as a model or even the queen of science in c19 europe in drawing on history of science media studies information studies and diverse textual methods this project offers that holistic account of how and why philology as a science in the making achieved such extraordinary success it articulates the widely sought yet unachieved bridge that would permit rigorous interdisciplinary exchange between philology its historical and contemporary iterations and presentday endeavors in the fields of digital humanities critical data studies infrastructure studies and depostcolonial studies phisci takes philology seriously as a science and gives it the kind of treatment that has dominated history of science for the last generation pioneering a novel account of philology from the french revolution to first world war it pursues a central question how did local ensembles of protocols representation instrumentation and cooperation consolidate into robust programs for the genesis of stable knowledge and knowledge communities it gives special attention to heterogeneity and universality in key concepts and practices and to physical aspects like media and infrastructure elements undervalued or rarely grasped in terms of their epistemic work for producing data evidence and facts phisci will thus explain how philology operated as a relational system that in the diversity of its data and perpetual flux in its projects and personnel projected unity that enabled it to wield a scientific authority greater than the sum of its parts
a calorimeter at atomic resolution

molecular interactions are at the basis of all biological processes and often include specific interactions between macromolecules protein rna dna and smallmolecule ligands such as cofactors hormones drugs or metabolites detailed and quantitative knowledge of these interactions is critical for a molecular understanding of these biological processes and developing new therapeutic solutions a complete comprehension of molecular recognition requires a full characterization of the geometry and dynamics of the molecular complex this includes not only the internal dynamics of each partner but also the dynamics at the interface which to date remain mostly unexplored experimentallythe physical chemistry frame for studying intra and intermolecular interactions is thermodynamics the extent to which two molecules interact is dictated by the gibbs energy change g of the interactions which is composed of enthalpic h and entropic s termsxray crystallographic and nmr structures provide a detailed description of the static interactions associated with enthalpic contributions however up to now the entropic components remain difficult to address experimentallythe overarching goal of this proposal is to develop a calorimeter at atomic resolutionto achieve that goal a new nmr spectroscopy approach relying mainly on the nuclear overhauser effect will be developed it is anticipated that quantitative thermodynamic measurements within molecules and molecular complexes will open a new avenue in the fundamental understanding of how atomistic mechanisms create a functionbeyond the fundamental findings we foresee applications in translational medicine drug design and computerassisted molecular design