Dragon09/odtu_chatbot huggingface dataset:
ai and robotics for prostate biopsy

the robiopsy project aims at evolving the robotic device for prostate cancer pc biopsy demonstrated during the ercpoc prost into a product prototype that will be ready for clinical trials the focus of the project will be twofold the engineerization of the prost prototype and the accurate analysis of the business case of prostate cancer diagnosis and its potential extension to focal therapy we will correct the shortcomings of the preclinical tests meet the strict medical certification regulations and address the health economics implications of our solution robiopsy will achieve better performance than current competitors because it solves the two main causes of pc diagnostic error uncertain target identification and inaccurate needle positioning as demonstrated in the preclinical tests a novel image fusion method will permit to significantly reduce the target uncertainty while the robotic device will zero the positioning errorthe robiopsy prototype will consist of a single cart holding the robotic needle positioner and housing all the electronic components the electronics will be divided into two subsystems interface and data processing and safety critical controls this will reduce the operational risks and will simplify the medical certification a multicentric study is ongoing to collect biopsy images to train the machine learning algorithms for prostate segmentation and lesion identification in parallel to the technical development we will analyze in depth the business case of prostate biopsy in selected european countries we will analyze the timecost reduction due to the new device and will establish the economic foundation of focal therapy to be ready for the expected evolution of pc treatments
citizenoriented valorisation for advancement learning and uptake in europe

the overall objective of covalue is to boost uptake and deployment of research results by adopting a covalorisation approach that strengthens the role of societal actors in knowledge valorisation citizen engagement will be embedded in knowledge valorisation by deploying capacity building peer learning actions and experimentation covalue will capitalise on and contribute to eu initiatives such as the knowledge valorisation platform through the production testing and improvement of best practices and lessons learned in two european territories alicante in spain and emilia romagna in italy in each territory quadruplehelix stakeholders from the research innovation ecosystem will be involved in the codesign and implementation of covalorisation exploiting ongoing knowledge valorisation processes such as developing innovative solutions to address the lack of raw materials and its impact on citizens welfare alicante or specific funding schemes and projects to introduce multistakeholder engagement in publicfunded research emilia romagnathe transfer of best practices and skills will be guaranteed by a comprehensive scheme of capacity building peer learning and shadowing opportunities both at local and international level the involvement of umbrella organisations such as ebn errin and universities alliances will foster a wider uptake of covalues trainings and tools thus supporting the implementation of new practices by knowledge valorisation agents beyond the project consortium incentives for researchers to engage with society and for society to engage with researchers will be codesigned with stakeholders in each territory and implemented throughthe involvement of local ri public administrations tangible changes in local covalorisation agents will be exploited to showcase improvements together with a coassessment of enabling conditions processes and impact performed together by all stakeholders involved
realization and imaging of superconducting spinwave optics

spin waves are collective excitations of the spins in magnetic materials they play a central role in the thermodynamics of magnets and are promising signal carriers in classical and quantum information devices spin waves offer nonreciprocal transport low damping microscale wavelengths at microwave frequencies and strong interactions that enable signal conversion as such spin waves have raised the hopes of enabling information technology with functionalities and efficiencies beyond those provided by noninteracting particles a key requirement is realizing efficient lowdamping spinwave control a potentially groundbreaking but virtually unexplored method is provided by superconductors superconductors have no electrical resistance precluding damping by eddy currents and a strong diamagnetism that enables strayfield control of the refractive index governing spinwave transport moreover superconductors are sensitive to electric currents magnetic fields temperature and light providing tunability as such superconductors provide unique opportunities for realizing lowdamping tunable spinwave optical devicesi propose to realize and locally study superconducting spinwave optics i will create spinwaveoptical devices mirrors waveguides beamsplitters and resonators by harnessing the dissipationless superconducting diamagnetism i will then demonstrate the power of superconductorcontrol by tuning the devices using electric currents magnetic fields temperature and light in addition i propose to use superconductors to engineer spinwave damping and enter new regimes of flatband and topological transport to locally study spin waves underneath superconductors i will use magnetic imaging based on spins in diamond a technique pioneered by my lab the project thus aims to engineer and understand magnetsuperconductor interaction realize tunable lowdamping spinwave devices and launch the field of superconducting spinwave optics
empowering widening universities in eutopiahealth consortium to foster academic excellence in health

challenges in health require integration of knowledge and communication between specialists from different healthrelated fields to develop effective solutions the eutopiahealth project a eutopiahealth consortium initiative aims to create a novel and innovative framework for the integrative academic management of healthrelated scientific areas facilitating changes in the academic landscape within the european research area through a comprehensive institutional transformation the project targets three widening countries romania slovenia portugal of the consortium that have traditionally lagged behind in healthrelated domains striving to overcome funding and publication disparities and spearheading academic excellence and innovation in these critical domains therefore the project aims to empower institutional transformation by strengthening healthrelated ri management capacity upgrading and adapting ri management strategies and policies within widening heis of the project consortium in line with the principles of the european research assessment reform a healthfocused ri network within eutopiahealth consortium will be established through connected health research communities that will receive intertransdisciplinary trainings research mobilities for earlycareer researchers and seedfunding for research collaborations all centered around healthrelated challenges by employing integrative transdisciplinary approaches and implementing flexible academic career pathways in health the project focuses on creating a health innovation ecosystem bridging the health research communities to society business partners and policymakers by mainstreaming opencitizeninclusivecollaborative science practices and translating research into tailored social innovation supported solutions eutopiahealth project through its comprehensive activities will positively impact the ri achievements research excellence international visibility funding absorption rate of the widening consortium heis and of entire eutopiahealth consortium
twinning with isma to develop innovative calorimeters for high energy physics based upon advanced scintillation materials

twismas overall aim is to boost the scientific excellence and innovation capacity of the institute for scintillation materials isma and its highquality twinning partners cern and institute of light and matter to develop innovative calorimeters for high energy physics hep based upon advanced scintillation materials to achieve this aim twisma will implement a research and innovation strategy over three years based upon five objectives implemented via five corresponding wpsobjective 1 conduct exploratory research on innovative calorimeters for hep based upon advanced scintillation materialsthe objective is to develop a prototype homogeneous calorimeter based upon bismuth germinatesilicate oxides plus a prototype sampling calorimeter based upon cedoped garnet fibres both calorimeters for application in hepobjective 2 transfer knowledge between experienced researchers ers of isma and twinning partnersthe objective is to organise short term staff exchanges trainings and seminars for ismas ers and the twinning partners ers to complement the preparatory research undertaken in objective 1objective 3 enhance career prospects of earlystage researchers esrs of isma and twinning partnersthe objective is to enhance the career prospects of ismas esrs and the twinning partners esrs by organising short and mediumterm exchanges training workshopsseminars summer schools and a joint phd programmeobjective 4 improve ismas management administrative capacity for european rd programmesthe objective is to improve the skills of ismas planning department in proposal preparation project management and innovation management for european rd funding programmesobjective 5 raise the research profile of isma the twinning partnersthe objective is to raise the research profile and scientific reputation of isma and the twinning partners through a comprehensive range of dissemination exploitation communication and outreach activities
epos optimization and evolution

the european plate observing system epos is the sole distributed paneuropean research infrastructure ri for solid earth science enabling open access to highquality multidisciplinary data products and services based on the achievements of the previous eu projects on the design implementation and preoperation of the epos ri the epos on project will support the consolidation of the infrastructure and pave the way for its further evolution the project will enable the epos ri to meet longterm sustainability conditions for operation relying on its ability to create value for the scientific and it communities and to produce new insights for contributing to societal challenges related to risk management and environmental impact reduction epos on aims to enhance the epos services portfolio and develop new institutional and scientific collaborations by fulfilling the needs of different communities and by encouraging the establishment of new epos thematic core services this will provide the necessary impulse to expand access to data and services to a wider pool of users in particular early career researchers at both the european and global scale user engagement will also increase thanks to the new generation of processing and workflow services developed during the project epos on is also devoted to shortening the gap between science and the private sector by enabling knowledge transfer and technological innovation as a result epos on will reinforce the epos capability to unite scientific communities and countries reducing fragmentation in the european research area epos on offers a timely opportunity for the optimization and evolution of the epos ri and reflects the strong commitment of its community to boosting epos impact
the oceans role in mitigating climate change mechanistic understanding of the legacy of anthropogenic heat and carbon in the ocean under netnegative carbon dioxide emissions

the ocean has absorbed vast amounts of anthropogenic carbon and heat canth and hanth respectively due to humans carbon dioxide co2 emissions to the atmosphere and resultant atmospheric warming we expect absorbed canth and hanth to leak back to the atmosphere under netnegative emissions and atmospheric cooling yet such leakage and its impact on earths climate evolution are poorly understood earth system models used for such research do not resolve the most energetic features of the ocean that is ocean mesoscale features that mix and transport waters across ocean regions where most of canth and hanth is stored i hypothesize that mesoscale features accelerate the transfer of canth and hanth towards leakage sites with potential implications for climate under netnegative emissionswith the project ostia i will set out to test this hypothesis to do so the project team will set up an innovative tool an earth system model rich in ocean mesoscale features and equipped with a novel joint modeling approach for canth and hanth the earth system model will be exposed to a co2 emissions scenario that is consistent with a warming target of around 15oc by the end of the century includes netnegative emissions after 2050 and extends until 2300pioneering outcomes of ostia will be i a game changer in mechanistic understanding of the legacy of canth and hanth in the ocean for the next 10 human generations and ii to inform if current earth system models are fit to represent canth and hanth legacy effects caused by the ocean mesoscale under netnegative emissions the objectives of ostia are pressing given that delay in ambitious action to cut co2 emissions leads to further accumulation of canth and hanth in the ocean and a reliance on future netnegative emissions in order to meet promised climate targets a successful implementation of ostia will be a step change in the emerging research field of the oceans response to netnegative emissions
multimodal imaging of lung tissue based on libs maldi and histology fusion to unravel sarcoidosis causes

sarcoidosis is an inflammatory granulomatous disorder with unknown cause highly associated with occupational exposures it has geographically variable prevalence with an elevated cost for the patients it can be detected among metalexposed workers firefighters rock glass wool or agriculture workers the most prominent example being rescuers in the world trade center in 2001 the need for accurate information about the exposures and causes of sarcoidosis is a limiting factor for clinicians therefore supplying them with relevant information will improve the patients healthcare trajectorythe aim of imatlas project imaging analysis of tissues via laser spectrometry is to develop a novel multianalytical procedure based on libs and maldimsi in combination with standard histology to identify localize and relate exogenous and endogenous agents allowing to elucidate possible external causes and biomarkers of sarcoidosis a data analysis pipeline will be created containing all the biostatistical steps graphical representation exposure and biomarker search approaches as well as the image fusion results to provide a global view with elemental and molecular information of the tissue in addition to the pathologic information provided by histology the scripts will be publicly accessible available to other researchers as well as widely adaptable to different imaging techniques and instruments furthermore the results obtained will be released as an easytoread file quicklook to present all the useful multimodal analytical information to clinicians and optimize the diagnosis and treatment of patients
experimental investigation of co2 solubility trapping in heterogeneous 3d porous media

atmospheric co2 contributes to 23 of the earths global warming by greenhouse effect storing co2 in deep geological formations is the main mitigation measure currently available expeco2soltrap addresses solubility trapping st a trapping mechanism of co2 in dissolved form within the resident brine of the subsurface porous medium which allows storing co2 perennially by gravity st has been studied extensively in the last 10 years but numerical studies cannot account for the pore scale heterogeneity of the flow while most experiments cannot provide a full measurement of the system evolution in particular its dissolution flux recent groundbreaking experiments by the host group and secondmend group of expeco2soltrap have shown that the growth of the instability is orders of magnitude faster than that predicted by a darcy scale numerical simulation of the experimental process due to coupling beween the gravitatitional instability and the heterogeneity of pore scale flow this effect has been hitherto ignored in the literature furthermore the impact of darcy scale heterogeneity has hardly been studied in particular not experimentally expeco2soltrap proposes to i extend the experiments developed in the host group and secondment group to allow for pore scale measurement of fluid velocities threedimensional 3d granular porous media in order to fully understand the aforementioned coupling and ii to study the impact of darcy scale eg permeabilityporosity heterogeneity of the medium experimentally in granular porous media as well as in 3dprinted porous media of controlled heterogeneity two experiments both relying on refractive index matching of the flowing liquid to the solid phase but using respectively analogue fluids and dissolved co2 will be used in parallel pore scale concentration fields will be measured by laserinduced fluorescence and scanning by laser sheets while fluid velocities will be measured by stereopiv
management at a distance

multinationals mncs are key drivers of economic growth accounting for 33 of global output oecd 2018 however within mncs the economic performance of foreign affiliates declines markedly with distance from headquarters hq this pattern implies the existence of frictions that restrict how much economic growth foreign direct investment fdi can generate in host countries understanding the underlying mechanisms has important implications for the economic benefits of fdi and fdi policy yet they remain little understood in this project i propose a novel explanation management problems at a distance management problems can be severe even in purely local settings eg gibbons and roberts 2013 it is plausible that principalagent pa problems between hq and the foreign subsidiary manager rise disproportionately when different countries cultures languages and institutions are involved as previous research has been severely restricted by the scarcity of global organizational data on mncs so far there exists no systematic evidence on pa problems within mncs and how they can be resolvedi will focus on two solutions the employment of foreign subsidiary managers that have a certain connection to hq and the use of information and communication technology ict to improve monitoring problems i have been able to identify several novel data sources that can be combined to create the first comprehensive datasets on managers and ict use within multilocation firms in three historical and contemporaneous settings combined with innovative empirical approaches this allows me to provide the first tests for the existence of pa problems within mncs and study several channels through which pa problems can affect economic growth managerial compensation changes in risktaking and career incentives of middle managers i will estimate how these channels affect the economic performance of subsidiaries firms and host economies
methods and tools for comprehensive impact assessment of the ccam solutions for passengers and goods

mobility is crossing a new digital frontier in terms of connectivity allowing vehicles to communicate to each other to the infrastructure and to other transport systems users however the potential implications and impacts of integration of ccam solutions into the mobility system are not well understood neither for specific actors nor for the systems level move2ccam will i explore the impact of ccam passenger and freight solutions define use cases business models and kpis through cocreation activities with the satellites and ii develop a practical system dynamicsbased impact assessment tool that will enable the evaluation of ccam interventions impact on mobility socioeconomic public health and environmentalrelated aspects considering diverse european region specifics and different actors needs objectives and perceptions the satellites is a multisystems network of actors across the whole ccam ecosystem consisting of industries authorities researchers citizens and orbits around the project by participating in a series of cocreation activities case studies for different types of organisations dialogues social simulation experiments virtual reality games and av demonstrations take place in 8 european countries and at a paneuropean level to collect data and specify the multisystems impacts of ccams the impact assessment tool will allow stakeholders to test and evaluate the systemwide impacts of ccam interventions along with a range of complementary policies providing also a series of kpis within the project it is applied for helmondnl gzmpl and aegean islandsgr given these activities move2ccam significantly contributes to a wellfounded understanding of the impacts of ccams it will deliver impact evaluation frameworks and tools with kpis covering sectors such as society economy and the environment policy recommendations for ccam partnerships and largescale demonstrations and recommendations for sump
learning intentions following evolution

understanding why a certain utterance was said by a participant in a conversation is fundamental for successful communication to take place notwithstanding the central role of understanding intentions in communication this and other forms of pragmatic reasoning remain beyond the current stateoftheart in natural language processing nlp for this reason critical applications of these technologies such as personal assistants remain limited to few handcoded usecases such as adding events to a calendar and fail to serve as generalpurpose communicative assistants this proposal aims at making significant progress towards genuine natural language understanding nlu it introduces a system that can reason about the pragmatic meaning of a sentence by searching for useful explanations in a space that represents all possible concepts often called a language of thought because such a search process is generally intractable this project proposes to let the system discover the more efficient way to search to achieve this goal it will model an openended evolutionary process that is here hypothesized to lead to emergent exploration strategiesthis project bridges linguistics and complex systems with connections to cognitive science and evolutionary theory to maximize its success probability i will conduct it at the colt lab in universitat pompeu fabra upf a leading group in computational linguistics with a secondment at santa fe institute sfi a global leader in complexity science