Dragon09/odtu_chatbot huggingface dataset:
homescapes make the world we live in a multisited study to unpack morethanhuman homes in the urban south

global south cities have managed public services through sociotechnical configurations that provide differentiated alternatives depending on social position populations living in lowincome neighbourhoods which in the south accounts for 6070 of urban housing seldom have regular access to piped water they rely on smallscale providers rain harvesting and other arrangements nevertheless we do not know much about what happens once the water is transportedstored inside patios kitchens and other domestic spaces this is a broader trend we know little about the socioecological life within lowincome homes in the urban south this despite the fact that it is in these homes that many of the processes sustaining life in the city take place the question of how socioecological processes unfold within these homes is open and pressing especially considering the fact that global south cities are home to the majority of residents worldwide and if we do not understand how the majority live their intimate daily routines we cannot aspire to build inclusive sustainable futures homescapes follows water as it is essential for sustaining everyday life and goes beyond it into other material and atmospheric components of the home stored stagnant waters are never only water but are also home to communities of organisms such as bacteria and mosquitoes that eventually continue their lives outside of water the concept of homescape is proposed to denote a produced place in which interdependent social and ecological processes unfold in and around the domestic but are not independent of broader socioeconomic power relations and ecological dynamicsmethodologically this project will not treat southern cities as sources of data but as sites of theorization in their own right it combines multimodal ethnography and waterquality work approaches that are groundbreaking in building theoretical insights from a diversity of specific urban processes and contexts
economic and ecological recovery of indium gallium and germanium from industrial waste

the european green deal aims to achieve climateneutral europe by reducing greenhouse gas emissions to at least 55 below 1990 levels by 2030 the success of this target requires reliance on lowcarbon technologies that are depended on the availability of critical raw materials crm like indium in gallium ga and germanium ge besides the improvement of conventional mining technologies recycling of in ga and ge from solid industrial waste is one of the beneficial alternatives to ensure the availability of crm and meeting eu targets in future however the low concentration of crm and larger presence of contaminants like feal makes the recovery of crm from secondary resource uneconomic and technically unfeasible ecometalophosphore would overcome these challenges by applying phosphonium ionic liquid pil based solvent extraction sx and patented galiophore technology to recover in ga and ge from industrial wastes pilbased is a simple and costeffective process for removal of feal while galiophore technology will be able to selectively recover ingage from the leachate devoid of feal and upconcentrate prior to pilbased sx and galiophore technology soild waste will be leached through acidic leaching upon successful demonstration at the laboratory scale scaleup of the ecometalophosphore technology will be carried out at 500 ld scale to quantify the benefits of the developed technology life cycle assessment ecotoxicity analysis of leach residue and generated waste and costbenefit analysis will be carried out to ensure the costeffectiveness of the technology recycling of pil organic acids and siderophores will be attempted ecometalophosphore contributes to circular economy and innovative green technologies initiatives that enable a sustainable environmentfriendly and economic recovery of in ga and ge from waste products
molecular mechanism of lnpmediated intracellular delivery of rna

lipid nanoparticles lnps are promising for rna delivery yet their effectiveness is hindered by endosomal entrapment post cellular uptake limiting their therapeutic potential the challenge lies in the inadequate understanding of the endosomal escape mechanism this project aims to comprehensively replicate endosomal escape in vitro employing three objectives to explore lnp interactions with membranes and rna translocation objective 1 focuses on understanding the impact of ph and lnp formulation on lnpmembrane interactions employing supported lipid bilayers slbs mimicking endosomal membranes the binding and fusion rates of distinct lnp formulations will be examined using total internal reflection fluorescence microscopy this will highlight key factors influencing these interactions which constitute the initial step of endosomal escape objective 2 aims to reconstitute rna translocation across endosomal membranes using giant unilamellar vesicles guvs these vesicles simulate endosomal conditions enabling the visualisation of lnploaded rna translocation across vesicle membranes via spinning disk microscopy and fluorescence correlation spectroscopy this will offer direct evidence of the success of the second step of endosomal escape and insights into how various lnp formulations react to diverse ph conditions objective 3 introduces novel bifunctional phospholipids bps into lnp formulations to facilitate visualising lnp fusion with endosomes in live cells through confocal microscopy this technique also permits the visualisation of rna release and subsequent protein expression by addressing the endosomal escape challenge through innovative in vitro and cellular models this project aims to unravel the complexities of lnp interactions with cellular barriers the findings have the potential to enhance lnp design optimising endosomal escape mechanisms and ultimately improving their efficacy in gene delivery applications
oxygenmediated selfrechargeable organic batteries

climate change and energy crisis are the main societal challenges of modern times and are expected to plague the humanity for next decades the exploitation of secure clean and efficient renewable energy technologies can enable the humanity to cope with these two major issues liion batteries are one such key technology that can realize this in this proposal we are dedicated to explore and advance a new type of concept the oxygenmediated selfrechargeable organic battery solobat by combining the reaction chemistry of lithiumorganic batteries lithiumoxygen batteries and spontaneous oxidation of organic battery materials by the molecular oxygen we first set out to have a comprehensive study of the oxygenmediated lithiumorganic battery system and afterwards combine the oxygen catalysts and organic cathode materials to construct and test the solobat prototype systems specifically clarifying the exact reaction chemistry of oxygenmediated lithiumorganic battery establishing screening principles for organic cathode materials and oxygen catalysts and constructing a solobat system that can achieve a good cycling stability of more than 300 cycles are the main objectives in this project by combining my strong expertise in the field of lithiumoxygen batteries with the excellent background of host supervisor on organic battery materials effective implementation of the project is foreseen besides we anticipate that the successful completion of this project will lead to a new sustainable battery technology for rescue equipment and battling the climate change and energy crisis and set off a wave of research on this concept as well as provide great opportunities for me to reach a position of professional excellence and independence
the first inclass nonopioid drug for treating moderate severe and persistent pain with no addiction nor tolerance

tafalgie therapeutics is a biopharmaceutical research company developing a new scientific approach for nextgeneration treatments based on a true breakthrough innovation derived from the mechanism of action of an endogenous protein modulating the pain signal our ambition to become the reference player in the field of pain medication by designing and proposing new active pharmaceutical ingredients for nonopioid analgesics in a context marked by the opioid crisis through the development of firstinclass polypeptides derived from tafa4 and its peptide derivatives we aim to develop and bring to patients more effective welltolerated nonaddictive longterm treatments for the relief of acute pain mild moderate and severe as well as for the prevention of chronic pain
pathways of resilience and evasion of tipping in ecosystems

there is an urgent need to understand the catastrophic effects that global environmental and climate change can have on the earth its system components and ecosystems one area of critical concern is the imminent highimpact abrupt and irreversible tipping of ecosystems recent discoveries indicate that tipping could be evaded and even reversed in ecosystems through spatial pattern formation of vegetation thereby creating pathways of resilience many undiscovered pathways of resilience through spatial pattern formation could exist for tippingprone ecosystems this resilience could be even enhanced by the unexplored connection between spatial pattern formation and community assembly the aim of resilience is to fundamentally advance our understanding and predictions of tipping and critical transitions in ecosystems and reveal how these can be evaded and even reversed through spatial pattern formation the resilience team consists of fieldleading and complementary pis and is capable of addressing all aspects of this overarching project linking theory and observation spanning the fields of ecology physics and mathematics resilience will develop a new theory for emerging resilience through spatial pattern formation and link this with real tippingprone biomes undergoing accelerating global change savanna and tundra central to our theoretical approach is the novel mathematical connection between the origin of the formation of patterns and their resilience once they emerged our empirical approach will include the analysis of existing and new data from in situ observations and drone and satellitebased remote sensing our research will reveal which conditions and spatial patterns lead to the evasion and even reversal of tipping identifying these conditions and patterns will also expose how human interventions can prevent or reverse tipping and uncover that tippingprone ecosystems could be much more resilient than currently thought
role of mitochondria in mediating evolutionary rescue by anthropogenic pollutants in an invasive crab

invasive alien species ias are the cause of enormous socioeconomic and biodiversity loss across the world in the context of climate change and increased pollution ias are often more adaptive than native species capable of adjusting their phenology in accordance with climatic changes facilitating their invasion it has been recently suggested that rapid evolution allowing quickly adaption and avoiding extinction due to maladaptation is the cause of the increased invasive capacity of ias in mitorescue i take this concept one step further and i hypothesize that mitochondria being exquisitely sensitive to environmental stress and with a highly mutagenic dna are key organelles involved in rapid evolution resulting in evolutionary rescue i will study the combined impact of pollutants and increased temperature on an ancestral and an invasive recently established population of the european green crab an extremely prolific invader the study involves both field and laboratory approaches from the organelle to the wholeorganism it merges the fields of toxicology physiology evolutionary and molecular biology to provide a highly multidisciplinary and integrative perspective the final objective of this research subject is to predict future invasion scenarios identify novel targets to control ias proliferation and improve management and risk assessments of ias in europe and worldwide with mitorescue i will use a stateoftheart training in assessing mitochondrial plasticity to consolidate my career in europe and compile the necessary data to establish a research subject new to the era with great translational impact in the longterm this research will promote restoring europes biodiversity which is one of the four current key strategic orientations for eus ri it will contribute as well to the european green deal initiatives and the eu biodiversity strategy for 2030 by addressing ias socioeconomical management in a thermally changing world
machine learning for quantum

the marie skodowskacurie doctoral network ml4q machine learning for quantum provides highlevel interdisciplinary intersectoral and international training to 10 doctoral researchers who will explore how machine learning and quantum science technology can be combined to i extend quantum and classical machine learning based prediction of materials and matter properties and to stronglycorrelated regimes and ii accelerate the development of quantum technologies through machine learning thus enabling new approaches to solving outstanding problems currently out of reach of classical computers this has the potential to address some of the worlds most pressing challenges such as developing tools for discovering more environmentally friendly chemical processes and efficient materials or accelerating the development of quantum technologies which will give europe an edge in the global tech race ml4q fellows will realize this vision will through their individual projects and interdisciplinary collaborations reinforced by a comprehensive training program which combines cuttingedge research with a focus on networking career development for academic and nonacademic career paths open science and responsible research and innovation for society that will enable them to shape emerging technologies and the next digital transformation in europe the consortium consists of 5 academic and 5 nonacademic research partners including 2 leading eu qt startups and 11 principal investigators who bring together all the necessary expertise computer science ai and machine learning quantum technology and chemistry and materials science as well as their interfaces together we will prepare the next generation of strong resilient flexible and creative quantum and computer scientists with the combination of skills needed to meet the future needs of the rapidly evolving innovative materials quantum technologies industries as well as other knowledge based sectors
joint optimization of data and energy networks for digitizing sustainable communities

coalesce aims to develop a crossoptimization platform that enables integrated operation and interplay between the energy grids and the data and telecommunication networks telecommunication and data networks need energy while energy grids need data to operate efficiently this project will develop a framework that will optimize the interplay between energy grids and telecommunications and data networks in a way that both the infrastructure pillars energy and telecommunications are jointly sustainable and efficient through the staff exchange program we will be able to exchange expertise and knowhow between energy data and telecommunications sectors across both academia and industrywe will assess how the proposed architecture performs by validating the framework against 4 use case scenariosa to investigate optimization algorithms for energy efficiency under simultaneous wireless information and power transfer swipt will be investigated in a local energy system context for a wireless sensor networkb to develop a novel framework for predicting and validating trading optimization strategies for inhouse energy asset management considering battery storage flexible domestic demand windfarm solar cells etc using neural network and transfer learningbased models while maintaining sustainable and secure exchange of data and user or individual residence portfolioc to design novel set of measurement methodologies for the characterization of 5g6g rans energy consumption and open data sets for analysis parametric models of the energy consumption transfer function for the uplink and downlink and generative neural network models of the energy transfer function for the uplink and downlink d to formulate joint dataenergytransportation robuststochastic optimization algorithms considering computational load flexibility intermittent energy generation and storage and multiagent learning algorithms for collaborative etransportation and sles
researchers impact in everyday life

the brightnight 20222023 proposal within the framework of the european researchers night aims at bringing research and researchers closer to the general public of the tuscan region in fact the brightnight consortium includes the main tuscan universities whose decennial collaboration has already produced very successful ern events this objective will be achieved by showcasing research projects with a specific focus on sustainability and societal challenges through a rich and inclusive program of activities in open and public events throughout tuscany we will increase the awareness of how scientific research impacts on the daily lives of citizens on the active role it can play in shaping the future and fostering young peoples interest in scientific studies with a gender balance approach mostly in steamafter a set of preparatory events the core activities will take place the last fridaysaturday of september 20222023 hundreds of interactive funny and inspiring activities in the cities which will be populated by science hubs shows handson experiments games competitions and exhibitions to better stress the centrality of a joint european effort on the societal and sustainability challenges of our times the event will revolve around the horizon europe missions with particular emphasis on their interdisciplinary characterthe twoyear duration of the proposal will allow the involvement of students from primary and secondary schools encouraging to deliver a scientific presentation during the nights they will be supported by academic researchers who will help them to select and prepare a topic this activity aims at creating a longterm connection between researchers which will be trained on scientific communication skills for the purpose young students and the general public such connection will make science research more familiar more understandable and ultimately strengthen peoples trust in scientific methods
facing the past public history for stronger europe

public history helps to engage citizens in the coproduction and communication of the past while maintaining ethical and methodological standards strengthening social cohesion resilience and democracy in a digital age the aim of europast is to enhance the scientific excellence and research capacity of vilnius university vu and strengthen the profile of its staff in the field of public history to accomplish this aim the project will establish structured collaboration between scholars from vu and leading researchers on public history from the leibniz centre for contemporary history in potsdam germany zzf the centre for european studies at lund university in sweden lu and the centre for contemporary and digital history in luxembourg unilu the work plan envisages exploratory research on best practices of public history and models for the future a coordinated training programme delivered through a series of three summer schools research colloquia with special attention paid to early career researchers a series of research and institutional exchanges among project partners outreach workshops with public history practitioners and decision makers and the establishment of a network of research managersthrough joint research training and networking supported by an integrated set of dissemination exploitation and communication activities the project will establish a longlasting interdisciplinary research network distinguished by strengthened research and research management capacities stronger strategic networking and new more creative approaches to public history as a citizen science of the past the network will contribute to the enhanced reputation and profile for vu generating proposals for major new research projects the europast network will endure beyond the lifetime of the grant and will make an ongoing contribution to the diffusion of knowledge and best practices beyond academia
supporting european industry success maximization through empowerment centred development

seismec will demonstrate an empowered humancentred and ethical development of digital and industrial technologies in 17 pilots in 19 companies from 14 countries across 14 industrial ecosystems it will do so through a twoway engagement in the development of technologies empowering endusers and workers and supporting social innovation in a process labelled the seismec shift it will contribute to increased inclusiveness by supporting a humancentred approach to technology development that is aligned with european social and ethical values including gender and intersectional aspects the benefits of human centrism will be measured in creativity collaboration autonomy automation productivity privacy safety and job satisfaction the caps empowerment factors for humancentrismseimsecs twoway engagement introduces technical innovations such as explainability codevelopment feedback methods and interfaces to enhance human centrism but also incorporates plans needs and innovations from companies and their workers steering them towards an empowered humancentric industry 50 path the consortium brings together institutions at the forefront of engineering computer science networking and exploitation coordinated by a worldleading social sciences and humanities university and building up on groundbreaking european projects on industrial innovation seismec pilots are representative of all sectors and company sizes and most european countries and worker roles every industrial enterprise in europe will be able to see some aspect of their activity reflected in seismecs pilots and will be able to learn from the projects outputs through an active campaign of crosssector empowerment practices exchange with a strong engagement of european national and local stakeholders seismec is landmark effort in european industrys shift to empowerment and humancentrism one that puts the worker and european values at the core of its global competitiveness