Dragon09/odtu_chatbot huggingface dataset:
resilient agricultural irrigation systems for water scarcity in europe

in the last years extreme weather patterns of water scarcity droughts and water abundance floods rapid showers are becoming more frequent and prolonged in the eu if we do not remedy this situation by 2050 water scarcity will lead to 122 billion losses per year and affect 17 of eu population rains will contribute to improve the resilience of eu agriculture to water scarcity by demonstrating 10 solutions irrigation practices technologies and tools that will increase the efficiency of water and nutrient management in agriculture and reduce the impact of extreme weather events rains solutions include alternative forms of water supply combined use of water and biofertilisers improved soil waterretention waternp modelling and some smart solutions optifangsia wateriq to contribute to decisionmaking and to integrated irrigation management across farm systems solutions will be demonstrated at 10 demofarm systems representing agroecology organic production conventional intensive and urban agriculture replicated in greece and spain we will also develop a hydrological and np model to optimised agriculture production at catchment level a well we will conduct cocreation workshops knowledge transfer activities and create materials such as guidelines 2 white papers 2 and practice abstracts 40 policy focused sessions will deliver 3 sets of policy and incentives recommendations engaging quadruple helix agricultural stakeholders to pave the way for the uptake of sustainable irrigation and fertilization management solutions in practice in the euin the long term rains will contribute to improve water efficiency by 50 in 12700 ha in more than 20 eu regions and support 500 farmers in the transition to a more sustainable irrigation and by 2050 the implementation of the rains project will save up to 61 billion 244348 million litres of water and 354 t co2 eq avoided emissions
biochips biofabricated microfluidcs chips based on self assembling of cncs to recreate the hierarchical fibrillar structure of human tissues ecm

biochips proposes an innovative bottomup strategy to directly fabricate cellladen devices that recreate the unique biophysical cues from the native fibrillar ecms and allow the design of bioengineered microtissues with arbitrary geometries the proposed platform combines the concepts of matrixassisted 3d freeform bioprinting with the controlled selfassembly of colloidal cellulose nanocrystals cncs to fabricate cellladen constructs embedded within its own fibrillar cnc hydrogel device the proposed platform can array multiple independent single organ models in a highthroughput manner number will depend on the desired model complexity and well plate used or link multiple tissueorgan models together with microfluidic circuits that can be userdefined on their cad designs the biochips system enables highresolution printing of complex and perfusable multicellular constructs without separating membranes or plastic barriers where cells can interact through signaling gradients created by compartmentalization in a bioinspired fibrillar matrix and supporting their longterm culture in addition to optical transparency for real time monitoring cncs hydrogels can be bioorthogonally digested to release the embedded constructs for postbioprinting analysis and processing which is a crucial advantage in organtissueonchip applications beyond the fabrication of perfusable microfluidic channels and cellladen chambers for the development of 3d microphysiological systems as in vitro models the intrinsic characteristics of this bioinspired platform further enables its scale up to produce tissue engineered constructs within its own bioreactor for in vitro maturation and biological tests at higher scales
laserbased infrared vibrational electricfield fingerprinting

a biological systems phenotype and the evolution thereof are mirrored in molecular composition the complexity of biological samples however renders quantitative multivariate molecular probing challenging in particular for nondestructive labelfree approaches vibrational spectroscopies capture signals from all molecular bonds exchanging energy with an optical excitation delivering highlyspecific optical fingerprints of samples in their native state to which virtually all molecules contribute yet while infrared ir spectroscopies profit from large vibrational crosssections technical limitations of ir radiation sources and detection have so far limited their applicability to realworld biomedical settings in particular in the context of highly absorbing water ubiquitous in biological samples the project live aims at harnessing the unparalleled control over light on the level of individual opticalfield oscillations afforded by femtosecond lasers and nonlinear optics to overcome current technological limitations and advance ir spectroscopy toward the fundamental limits set by the nature of light and thus toward the ultimate sensitivity specificity and throughput achievable in optical vibrational fingerprinting to this end we envisage the development of powerful sources of fewcycle pulses covering the entire ir molecular fingerprint region 5004000 cm1 with utmost electricfield waveform stability and of innovative electricfield sampling techniques capturing nearly all photons emitted by linearly and nonlinearly excited molecular vibrations the host institution permits immediate validation of these developments for realworld biomedical samples including highthroughput vibrational fingerprinting of individual cells in flow cytometry spectral tissue histopathology and highresolution highsensitivity breath gas monitoring thus live promises direct impact on patients health deeply rooted in basic photonics research
place and empire in irish literature and culture

place and empire investigates the relationship between medieval irish topographical literature and the development of medieval irish imperialism and anticolonialism this project shows that irish topographical literatureknown as dindshenchashas always been a political tool and that was initially cultivated to translate ideas of classical imperialism onto an irish landscape using the latin epic tradition irish literati conceptualised irish imperialism by composing origin narratives which validated authority over places between the 9th and 12th centuries these ideas were encoded into narratives about politically significant places under the patronage of dominant irish dynasties in the wake of the anglonorman invasion in the 12th century the imperial impulse turned anticolonial as irish topography was coopted as an intellectual bulwark against colonial rule the political use of irish topography also finds parallels in contemporary medieval welsh sources dealing with ireland these sources foreshadow british imperialist designs and illustrate how irelands colonial othering by its neighbour was articulated through topography irish topography was similarly connected to british colonial practices in the 19th century since the modern reception of the topographical literature began as part of an irish ordnance survey project in the 1830s under the auspices of the military branch of the british empire engagement with places in reaction to major political shifts is not an exclusively medieval phenomenon watershed events like brexit or the war in ukraine challenge our notion of the immutability of modern european borders and conjure the spectre of imperialism anew the recent trend which sees welsh heritage sites adopting their original welsh names and the tabling of the question of irish unity are different reflexes of the same concern with places among the irish and british public
climate science for evaluation of changing socioeconomic impacts

climate change cc poses numerous risks to society amongst these recent work has quantified the impacts which adverse climate conditions can exert on economic growth and inflation by applying empirical models ems to historical data evaluation of the extent to which historical and future cc is changing such impacts is crucial for translating these empirical insights into actionable knowledge two key examples are quantifying the historical anthropogenic contribution to intensified impacts and accurately projecting their nearterm changes these tasks face challenges because climate model ensembles often underestimate forced changes in impactrelevant conditions such as extremes and nearterm changes are affected by both greenhouse forcing and internal variability with the latter amplifying or masking impacts over decadal timescales klesis proposes to extend recent methodological developments in climate science to overcome these obstacles to an accurate evaluation of how climate impacts are changing first we will develop and apply statistical methods to attribute historical changes in impactrelevant climate conditions directly from observations these methods will be tested in climate models applied to observations and combined with ems to evaluate the anthropogenic contribution to historical changes in climate impacts on the economy crucial for informing loss and damage debates second we will extend stateoftheart decadal climate prediction systems to include impactrelevant conditions combining these with ems will provide nearterm estimates of climate impacts which accurately reflect the important and otherwise neglected role of internal climate variability finally nearterm projections of impacts on economic growth and inflation will be disseminated to stakeholders at the european central bank via a 6month nonacademic placement to develop a framework for the assessment of physical climate risk in their quarterly macroeconomic forecasts
personalised mechanobiological models to predict tumour growth and anticancer drug penetration

personalised cancer medicine presents an exciting frontier in healthcare that tailors disease mitigation and intervention to an individual patient however existing technologies fail to leverage the physical forces that underpin stressdependent tumour growth and the subsequent evolution of biomechanical resistance to anticancer drugs furthermore the fundamental mechanisms governing such forcesensitivity have yet to be uncovered this deficiency in scientific understanding of the active biomechanical behaviour of tumours and control of drug penetration has hindered the progression of anticancer therapy in this project an advanced computational modelling framework will first be developed to uncover the mechanisms underlying stressdependent cell and tissue growth coupling the thermodynamics of cellular volume control with active force generation and intracellular transport novel experimental analysis of 3d tumour spheroid growth and single cell biomechanics will reinforce the framework to gain a new understanding of how mechanical loading can prevent tumour cell division and the role of intracellular exchange in multicellular growth control the models will then be extended to determine the role of growthinduced stress and cell compaction in restricting drug penetration and whether this can be mitigated by promoting intracellular drug perfusion finally integrated patientderived computational and tumour organoid models will be developed for prediction of growth and emergent biomechanical resistance to anticancer drugs motivating modelled mechanobiological therapy in an animal model of breast cancer the overarching objective of this groundbreaking project is to pioneer a personalised healthcare framework for prediction of mechanicallyregulated cancer and treatment outcomes with remarkable potential to drive a paradigm shift in patientspecific diagnosis and treatment of cancer
melting and dissolution across scales in multicomponent systems

melting and dissolution induce temperature and concentration gradients in liquid systems these gradients induce flows namely buoyancy driven flows on large scales and phoretic flows on small scales such flows locally enhance or delay the melting or dissolution process and thus determine the objects shape on large scales a relevant example for the climate are glaciers and icebergs melting into the ocean where cold and fresh meltwater experiences buoyant forces against the surrounding ocean water leading to flow instabilities thus shaping the ice and determining its melting rate another example is the dissolution of liquid co2 in brine for co2 sequestration next to buoyant forces also phoretic forces along the interfaces come into play for dissolving drops at the microscale the phoretic forces become dominant the resulting marangoni flow not only affects their dissolution rate but can also lead to their autochemotactic motion deformation or even splitting in spite of the relevance for these and many other applications such multicomponent multiphase systems with melting or dissolution phase transitions are poorly understood due to their complexity multiway coupling feedback mechanisms memory effects collective phenomena the objective of this project is a true scientific breakthrough we want to come to a quantitative understanding of melting dissolution processes in multicomponent multiphase systems across all scales and on a fundamental level to achieve this we perform a number of key controlled experiments numerical simulations for idealized setups on various length scales inspired by above sketched problems but allowing for a onetoone comparison between experiments and numericstheory for the first time we will perform local measurements of velocity salt concentration and temperature and connect them to global transport processes to arrive at a fundamental understanding of such stefan problems in multicomponent systems
transforming data processing efficiency pioneering memory functionality in silicon photonics for sustainable and highperformance computing

this project aims to address the pressing issue of energy consumption in data transmission and processing by developing materials technology for efficient memory computing currently data centers consume a significant amount of electricity and traditional computing architectures are inefficient neuromorphic computing inspired by the brains functioning offers a promising solution with ultrafast communication and low energy consumption photonic processors which use light for probing are particularly attractive for achieving these goals the project focuses on integrating advanced materials into existing silicon photonic siph platforms to create efficient reconfigurable circuits refractive index tuning methods in si are limited and the project seeks to overcome them by integrating materials like phase change materials pcms and suitable 2d transition metal dichalcogenides tmds to demonstrate optical memristors these materials can emulate neural systems offering control over switching energy consumption heat dissipation and other crucial parametersthe projects objectives include optimizing materials technology designing optical memristors based on pcms and 2d materials exploring new configurations with pcmmems investigating memory functionality in vo2 and demonstrating neural response the goal is to improve data processing speeds while reducing power consumption ultimately leading to energyefficient computing additionally the project aims to assess the environmental impact of these advancements through empirical cost comparisons the researcher envisions that this experience will empower them to become a highquality academic researcher with a focus on materials photonics overall the project addresses a critical need in the field of computing by developing materials technology for energyefficient memory computing aligning with the goals of the european green deal towards the pursuit of ultrafast lowenergy data processing
paludiculture demonstrations providing multiactor approaches and recommendations towards largescale deployment in the eu

the eu aims to cut greenhouse gas emissions ghg by at least 55 by 2030 this ambition requires fast mitigation measures within all sectors paludiculture is the productive land use of wet and rewetted peatlands and can reduce ghg emissions by up to 7080 it thus has a large potential to support the eus climate targets and biodiversity strategy and still provide farmers and landowners with income but only if the practice is scaled up currently there are too few largescale sites involving local actors that demonstrate industrial scale paludiculture farming modelspaluwises 4 largescale paludiculture sites in finland the netherlands poland and the united kingdom will showcase best practices and solutions for converting degraded organic soils to paludiculture they develop fieldscale operations and their associated five value chains crops downy birch reed sedges typha reed canary grass by having two established nl uk and two new sites fi pl paluwise can demonstrate different stages of paludiculture and associated value chains emphasising replicability and scalability network sites eg paludizentrale germany will provide lessons learnt guidance and engage actors in innovating improvements eg maintaining high water levels adapting machinery choosing suitable crop species a multiactor approach is applied to coinnovate and improve costeffective climate smart value chains activities cover the full sequence from deciding where to set up a site wp1 decision support tool for rewettability what works well in a site wp2 demos what are the benefitsimpacts in emission reduction carbon sequestration potential biodiversity and other ecosystem services at landscape scale wp3 wp4 and how to upscale and get support wp5 we will identify barriers and provide recommendations to boost improved policy and legislation for largescale deployment of paludiculture in europe
powering artistic and cultural entrepreneurship to drive the climate transition

pacesetters responds to the abstract challenge of the climate transitions by shifting from a model of entrepreneurship based on individual shortterm incentives to one that is driven by coagency and new capacities to act together in sustainable ways it does so by examining the concrete circumstances investigating possible support mechanisms and stresstesting instruments that enable art and culture creativity and heritage to drive the climate transitiontherefore pacesetters will set out tocreate knowledge from collaborative research to keep pace with the transitionpropose and test creative business models to set the pace of the transitionassess strategies of valorisation to push the pace of the transition this approach will identify and analyse advanced practices that run transversally across the cultural and creative sectors contextualise the outcomes of coresearch in realworld laboratories for social imagination further develop and promote the preliminary results of experiments in iterative support and evaluation frames the pacesetters approach centres on inclusion participation and iteration in order ensure that gender equity and diversity inform it at every step and on every levelthe result will be a critical evaluation and allencompassing demonstration of the actual potentials of the ccis to drive the climate transition while systematically analysing their impact on micro meso and macrolevelunderstanding the climate transition as a triple transition green digital and inclusiveinnovating apacesetters responds to the abstract challenge of the climate transitions by shifting from a model of entrepreneurship based on individual shortterm incentives to one that is driven by coagency and new capacities to act together it does so by examining the concrete circumstances investigating possible support mechanisms and stresstesting instruments that enable art and culture creativity and heritage to drive the climate transition
cryogenic onchip levitated optomechanics for a spin entanglement witness to quantum gravity

this proposal addresses one of the key challenges of modern physics understanding the interface between quantum mechanics and general relativity recently an experimental test was proposed that can directly witness the need to unify the two theories observing quantum entanglement between objects that only interact through the gravitational field a successful test would prove the existence of superpositions of spacetime and have farreaching implications on how we understand our worldso far no experimental platform exists that can meet the challenging central requirement for this test a picogramscale mass in a micrometrescale spatial superposition with a secondscale coherence time here i propose to build such a platformthe objectives of the research are to trap and levitate a picogram mass cool its centreofmass motion to the quantum ground state couple its motion to a controllable qubit system and finally produce and measure a spatial superposition of the massconsidering all requirements i identify the unique combination of techniques necessary to achieve this diamagnetic levitation at cryogenic temperatures using onchip superconducting coils onchip superconducting quantum interference device squidresonator based sideband cooling coupling to solidstate spin qubitscombining recent microfabrication techniques for chipbased confinement of microparticles highq resonant circuits and microscopic diamond membranes with spins it is now possible to realize this system in the lab my extensive experience with spins and nanomechanical systems as well as microfabrication and lownoise cryogenic measurements and leiden universitys infrastructure for vibrationisolated cryogenics supports closetoqgs objectivesthe research would represent a major step towards a spinbased entanglement witness of quantum gravity moreover each subobjective can benefit applications in force sensing and magnetic resonance force microscopy
ebrains 20 a research infrastructure to advance neuroscience and brain health

ebrains is a collaborative european research infrastructure designed to advance and accelerate progress in neuroscience and brain health this innovative infrastructure a legacy of the human brain project hbp is an ecosystem where researchers clinicians and experts from various disciplines converge to explore and analyze brain complexity from molecular and cellular levels to the functioning of the entire organ therefore the project aims to create a new standard for brain atlases from the micro to the macroscale link foundational multilevel data and connectomes in the healthy and pathological brain with atlases and models create digital twins through modelling and simulation as well as unique excellent and preferred services for fair neuroscience data the overarching goal of ebrains 20 is to foster a deeper understanding of brain structure and function with dedicated and mature software tools to facilitate the development of more effective treatments new drugs diagnostics and preventive measures for neuropsychiatric disorders we expect that ebrains 20 catalyzes progress in the field of largescale models running on hpc towards exascale and leads to innovative solutions for neuroinspired computing and cognitive technologies such as neurorobotics and ai sophisticated digital modeling and data analytics capabilities will benefit communities beyond neuroscience such as biomedicine we will advance ebrains technology platform services and the base infrastructure roadmap educate and train a new community of users and developers from academia industry and smes and ensure knowledge transfer ebrains 20 will become the neuroscience hub in the european infrastructure landscape through building strong links with the european data spaces eosc and eurohpc ju centers of excellences and other initiatives globally ebrains 20 will make a strong contribution to the new era of digital neuroscience and foster european leadership in this field