Dragon09/odtu_chatbot huggingface dataset:
the impacts of ocean finescale whirls on climate and ecosystems

whirls is about small processes having largescale impacts heat and carbon are the currencies of regional and global climate constantly exchanged between the ocean and the atmosphere this exchange is strongly influenced by finescales ocean eddieswhirlsthat flux heat and carbon towards or away from the airsea interface when the ocean gives up heat and carbon to the atmosphere climate is warmer and wetter and vice versa carbon that is fluxed towards the airsea interface where sunlight is available can be taken up by phytoplankton that form the base of the oceanic food web eddies and fronts alter vertical nutrient fluxes and ocean stratification which help shape biodiversity and ecosystems the proliferation of finescale processes and their interdisciplinary and largescale impacts are poorly understood in whirls we will use a synergistic and interdisciplinary approach to study finescale processes across a continuum of scales 1100 km and assess their impacts on airsea exchange and marine biogeochemistry and biodiversity we focus on the agulhas current system around south africa because it is a global hotspot of eddy activity oceanatmosphere heat exchange and marine productivity and diversity it is also a region that plays a key role for the global ocean circulation and global climate and climate change we will use multiple coordinated observing strategies including research vessels and a large ensemble of autonomous platforms to collect physical chemical and biological datasets across scales these data will be supplemented by highresolution models of the ocean and the atmosphere developed with a focus on the agulhas current system as well as the latest data science methodologies whirls will improve the understanding of finescale processes and its representation in future earth system models for better predictions and projections of the future climate
largescale multicore smart photonics using advanced design and configuration protocols to develop the largestscale programmable photonic processor

emerging communications and computing fields are pushing the limits of integrated electronics demanding growing performance and requiring to symbiotically team up with integrated photonics the development of multipurpose programmable photonic integrated circuits promises costeffective mass production and the system versatility required in novel dynamic processing scenarios however their scalability is a major challenge constrained both by hardware and softwareto unleash the potential of programmable photonics it is essential to create novel circuits and components as well as to redefine its fundamentals multicore architectures are a potential unexplored solution offering scalability multitasking and parallelization but key technology enablers are required to jump to practical largescale applicationsthe aim of this project is to develop the theoretical and technological fundamentals of programmable integrated photonics to unlock their limitedscale by developing the first largescale multicore programmable photonic processor and its application as a complexvalued neuromorphic computerto achieve this aim we will i identify the main scalability limits advanced photonic circuit architectures and component development solutions for largescale programmable photonic circuits ii develop a functional singlecore programmable photonic processor with more than 2500 phase actuators iii demonstrate largescale complexvalued coherent neuromorphic circuits and iv develop a functional 4core programmable photonic processor with more than 10000 actuators and demonstrate its experimental application to photonic neuromorphic systemslsphotonicss will have a major impact on highdensity integrated photonics circuits by facilitating a new paradigm of generalpurposeapplication advanced photonic computing and readytouse and flexible devices that will extend the penetration of advanced photonics technology into seamless areas of application
secured and intelligent massive machinetomachine communications for 6g

to satisfy the expected plethora of demanding services 6g is envisioned as a revolutionary paradigm to carry forward the capacities of enhanced broadband massive access and ultrareliable and low latency services in 5g wireless networks to a more robust and intelligent level this move will introduce significant new multidisciplinary research challenges emerging throughout the wireless communication protocol stacks including the way the mobile network is modelled and deployed the structure of 6g networks will be highly heterogeneous densely deployed and dynamic combined with the tight quality of services such complex architecture will result in the untenability of legacy network operation routines in response artificial intelligence ai especially machine learning ml semantic communication and digital twin dt are emerging as solutions to realize the fully intelligent network orchestration and management by learning from uncertain and dynamic environments aienabled channel estimation and spectrum management will open up opportunities for bringing the excellent performance of ultrabroadband techniques into full play additionally challenges brought by ultramassive access concerning energy and security can be mitigated by applying aibased approaches the overall research objective of the scion project is to develop and design the network systems for seamless wireless access for secure and intelligent massive machinetomachine communications for 6g in addition to technology development to meet the urgent needs for the future working force of the coming 6g era this collaborative project will create a training network for doctoral candidates who will contribute to the design and implementation of future 6g networks
unravelling specificity of epimetabolic regulation in mouse development

when environment of the embryo changes or when development progresses metabolic reactions are rapidly affected these alterations to chemical reactions are coupled to epigenetic memory however without mechanistic data on how this coupling occurs it is difficult to understand how normal embryogenesis can proceed this project will elucidate how metabolic changes result in specific epigenetic outcomes and address the function of such regulation as a model we will use mouse implantation a process tightly linked to dramatic alterations to chromatin and transcription we found that this is also associated with extensive metabolic rewiring and that disrupting metabolic flows results in both lineagespecific and markspecific changes to chromatin while multiple studies uncovered that metabolism fuels chromatin modifiers with cofactors the fundamental biological question of how specificity is achieved remains unanswered here we will address this challenge by directly testing the three most likely hypotheses 1 that metabolic reactions shuttle into the nucleus where they specifically fuel chromatin changes 2 that chromatinbound metabolic enzymes regulate gene expression and 3 that only specific chromatin modifiers are sensitive to metabolic changes to address these questions we will go beyond description as we supplement multiomic approaches with mechanistic experiments both in vitro and in vivo firstly will use perturbations of nuclear metabolic enzymes and their chromatin binding secondly we will implement protein engineering to render chromatin modifiers resistant to the availability of their cofactors by uncoupling epimetabolic regulation we seek not only to uncover its importance for controlling chromatin states but also the implantation developmental program this project will form a framework of how future studies can mechanistically unravel intertwined regulatory processes and assess the role of environment and nutrition in early pregnancy
bioinspired legged underwater robots for ecological monitoring and exploration

a deeper understanding of marine ecosystems is crucial to enforce protective actions and promote a sustainable exploitation of the oceans resources adequate spatial and temporal coverage of data can be obtained by resorting to a network of fixed and mobile platforms to combine the advantages of different types of units existing mobile platforms such as autonomous underwater vehicles auvs and seabed crawlers present intrinsic limitations when operating in the benthic environment which can be overcome by underwater legged robots ulrs ulrs with arthropodlike versatile locomotion are not much affected by currents drain little power while keeping a fixed position exhibit a gentler interaction with the seabed and produce a lower acoustic signature in comparison with propeller driven vehicles the blue project aims at bringing the advantages of bioinspired ulrs in ecological monitoring applications by combining their capabilities with those of fixed and mobile platforms this aim will be pursued by 1 demonstrating tethered integration of a bioinspired ulr with a fixed monitoring platform ie underwater cabled observatory to perform visual census of the ictic community and by 2 implementing a collaboration between a bioinspired ulr and an auv to demonstrate obstacle free navigation to undertake this research i will join the marine science institute of the spanish national research council worlds expert in the ecology of the mediterranean sea additionally i will carry out two secondments at the university of girona and at the polytechnic university of catalonia to receive training on mobile and fixed monitoring platforms and gain access to unique facilities such as the auv girona500 and the obsea cabled observatory this project will contribute to the development of new tools for underwater operations with potential impact in scientific and commercial sectors and will establish the proponent as a prominent researcher in underwater robotics
mobilizing advanced partnerships for digital innovation and transformation

in europes digitally transforming business landscape innovative smes and startups in widening countries are pioneering change in their region yet face challenges like limited resources and complex ri ecosystems for internationalization concurrently eu ri networks seek to expand and include these widening entities for a more inclusive costeffective development mapit aims to bridge this gap by linking innovative smes research entities and european ri networks this project comes in the wake of structural funds granted to establish four digital innovation centers in turkish research entities and one in estonian where innovative smes will be hosted and can access the ri capacities via the research entity mapit aims to increase the participation of these entities in horizon europe strengthening universityindustry partnerships the project has two core objectives the roadmapping strand employs action research methodologies and a conversational ai tool finetuned with information from sources like cordis for discovering and planning complementary ri partnerships this will let the research entities build clusters and collaborate with ncps towards sustainable international ri portfolios the future studies strand delivers a comprehensive international ri managers and administrators upskilling program enriched by transformative visits and shortterm secondments these interconnected strands work synergistically to facilitate sustainable internationalization and human resource development within ri clusters by focusing on best practices joint initiatives and collaboration mapit aims to empower the five participating research entities with the organizational structure and ri capacities needed for joining the era fulfilling the widera objectives mapit not only offers a participatory methodology that can be replicated by other widening entities but also promotes synergy with european institutions and foster innovation across borders
personalized prognosis in smoldering myeloma through automated analysis of mutational signatures

multiple myeloma mm is the second most common haematological cancer which is symptomless until the later stages with few treatment options and poor longterm prognoses nextgeneration dna sequencing ngs has been used to identify and characterise the process of clonal evolution and disease progression in asymptomatic mm however there remains no viable prognostic ngs method which can be used by clinicians to leverage different mutations to predict progression the scientific literature indicates the methods under research utilise large genomic regions and significant coverage in sequencing that would result in prohibitively high costs of testing if applied to the clinical domain the aim of this poc project is to develop a complete lowcost prognostic bioinformatics tool able to characterise the driver mutation signatures of mm in order to allow early diagnosis monitor progression and potentially identify at risk patients that may benefit from early treatment to improve outcomes
dryprocessing of metal halide perovskites into thin films

perovskite semiconductors are promising for photovoltaics with a potentially very large market industrial compatible deposition processes that do not employ solvents are unavailable currently we have developed a new deposition process that is completely solvent free compatible with a wide range of perovskite precursors operates at moderate vacuum levels and leads to high quality films with crystal grains in the order of 500 nm in the aperitif project we aim to attract industrial sponsors both equipment manufacturers and photovoltaic module producers to license this novel process and use it to build a larger scale prototype and implement it for larger area solar cells to do this we will protect this process and the novel perovskite compositions and subsequent solar cells by filing patents in view of the superior perovskite film quality we expect to obtain more efficient and stable photovoltaic devices as the processing method is compatible with continuous operation it allows for high speed production something that is urgently needed to address the enormous growth scenarios of photovoltaic panels
waste to worth a green solution for waste concrete powder and incinerator bottom ash reinforced by co2 capturing in concrete

the worlds population is growing continuouslyand the waste generation is too in 2019 1052 m tonnes of the total eu waste generated was landfilled 30 of which was from the construction sector in particular waste concrete and municipal incinerator bottom ash iba proper management of these wastes is one of the most important responsibilities to provide a healthy environment for future generations moreover reducing co2 emission to at least 55 below 1990 levels by 2030 is a must to reach a carbonfree society aligned with the european green deal hence the proposed project aims to utilize waste concrete powder wcp and iba as alternative materials to cement and thereby convert these solid wastes into worth this also helps to satisfy the cement demand in the construction industry as a massive co2 emitter the main objectives of w2wgco2 are to treat the wcp and iba by co2 capturing from emitted flue gas of cement plant to manufacture the cementitious composite cc from carbonated wcp and carbonated iba and to study the performance of the cc in the green concrete application this proposal involves extensive training of the researcher on the carbonation treatment method and green concrete technology in the host ntnu and advanced characterization of the carbonated wastes in the academic secondment ietcccsic life cycle assessment of carbonated solid wastes and green concrete products will also be studied to highlight the environmental impacts of the proposed project in addition to the environmental benefits the success of the project will boost both research and complementary skills of the researcher including learning new experimental and analysis methods communication teaching and supervision skills writing eu patent and erc funding also the expected results will be published in highimpact journals which improve the profile of the researcher and makes her a competitive person in the field of sustainable and green building materials
porous polyionic liquids for co2 capture and simultaneous conversion under ambient conditions

co2 capture storage and utilization is judged critical to mitigate the rapid rise in the atmospheric co2 concentration a key problem is the gigantic mass of co2 emitted which asks for robust efficient and economically viable approaches that are currently missing and limited by the lack of suitable materials to break through this barrier i aim to develop metalfree dualfunction porous polyionic liquids dpps to capture and convert co2 under ambient conditions into cyclic carbonates with high efficiency and to apply them in model reactors for costeffective processing of co2polyionic liquids pils are innovative ionic materials in which ionic liquids ils are covalently joined by a macromolecular backbone ils are known co2philes and ilderived pils are naturally in favour of co2 sorption while their ions can be tailormade for catalytic co2 transformation such dualfunction as sorbent and catalyst is the intrinsic merit of pils to address the co2 challenge but unfortunately has been long impeded by the mismatched chemical structures in each function our preliminary work proved that the newly emerging 124triazolium pils were catalytic active and drastically more co2philic than common polyimidazoliums and are believed as the gamechanger materials we envision that by structuring chemically tailormade 124triazolium pils into highly porous materials they will be able to capture and convert co2 under ambient conditions this groundbreaking materials concept will circumvent the complicated harsh conditions for co2 fixation and cut the cost to an affordably low levelthis project will radically advance scientific knowledge and technology to fixate and convert co2 at scale into valueadded chemicals that further reduces the consumption of fossil resources its outcome will expedite the research in pil and dualfunction materials to revolutionize the ccu routes and equip us with powerful materials tools to mitigate the global co2 rise
secure interactive environments for sensitive data analytics

the fair principles provide a framework for enabling proper access and reusability of scientific data and implementing them is a key goal of the european open science cloud eosc however providing access to sensitive or confidential data while preserving privacyconfidentiality and usability for researchers is still an open question existing solutions like safe rooms safe pods or data safe havens are often challenging for the development of reproducible research and seem counterintuitive when dealing with open science and fair principles the siesta project aims to provide a set of tools services and methodologies for the effective sharing of sensitive data in the eosc following a cloudbased model and approach siesta will provide userfriendly tools with the aim of fostering the uptake of sensitive data sharing and processing in the eosc the project will deliver trusted cloudbased environments for the management and sharing of sensitive data that are built in a reproducible way together with a set of services and tools to ease the secure sharing of sensitive data in the eosc through stateoftheart anonymization techniques the overall objective is to enhance the eosc exchange services by delivering a set of cloudbased trusted environments for the analysis of sensitive data in the eosc demonstrating the feasibility of the fair principles over them
respond rescuing democracy from political corruption in digital societies

corruption and undue influences are not only linked to democratic discontent but compromise the quality of democracy but how exactly does political corruption operate today how deep can its negative impact on democracy go and how can anticorruption efforts recover peoples support for democracy as a regime and promote their engagement with integrity and their refusal of undemocratic proposals and actions to address these crucial challenges for democracy respond proposes a novel interdisciplinary assessment of political corruption seen here as conducts and acts often proliferating in grey zones regarding legality that results in decisionmaking bias and exclusion in the policy cycle it does so by 1 analyzing four contemporary and relevant forms of political influence political finance lobbying revolving doorspersonal ties and media capture to understand when they become troubling forms of influences connected to specific political corruption patterns hence undermining fair competition and broad participation in political decisionmaking processes 2 evaluating how political corruption is understood by political elites and citizens and is socially constructed through media and education as well as its impacts on both democracys legitimacy and credibility and on responses to counter them 3 exploring how established and emerging digital technologies entangle with political corruption and how they improve anticorruption and prointegrity strategies at both national and crossborder levels 4 engaging in cocreation with relevant stakeholders to design test and revise practices and tools including new risk indicators developed by respond to increase civic monitoring and integrity in current democracies through a mixedmethod research design respond investigates 27 eu countries and 11 neighbouring countries to signal ways to make governments public officials and political parties perform better ethically and recover democracys popularity
epigeneticgeneticmental health cascade based personalised prevention of noncommunicable disease in adolescents diagnosed with autism ethereal

five noncommunicable diseases ncd diabetes cardiovascular disease cancer chronic respiratory disease and mental health disorders mhd account for 86 deaths and 77 disease burden in the who europe region of these five ncds mhd is unique as it has a complex bidirectional relationship with the other four major ncds meaning that on one hand it could be the initiator of the other ncds or other ncds could lead to mhd which in turn can further aggravate the primary ncd leading to a vicious circle recent research identified mhd as the highest ranked ncd in adolescent population a specific group in this population that is 3 6 times more vulnerable for developing mhd and subsequent ncd is the adolescents diagnosed with autism spectrum disorders asd there is no evidence based intervention ebi for preventing mhd in an asd adolescent since 1 the major risk factors are ingrained in their biological process and 2 they present with multiple mhd comorbidity personalisation is the key to prevent their already vulnerable mental states making transition to an mhd which ebi is appropriate for which asd adolescent and how to choose it an unsolved question because of their neurobiological characteristics personalisation must be done at biological levelrecent research showed how the environmental factors can alter gene expressions that leads to an mhd through epigeneticgeneticmetabolomicmental health egm process using quantitative modelling of this process ethreal will develop a personalised flexible single service delivery model that will empower an asd adolescent to selfcontrol their environmental factors while seamlessly accessing the community care services to prevent their mental health making transition to an mhd a unique solution for sustainable prevention of mhd and subsequent ncds in this population without loss of generality the proposed solution could be adapted to prevent mhd in wider adolescent population