Dragon09/odtu_chatbot huggingface dataset:
enzymelinked dna displacement elidis assay as an innovative immunoassay platform

since its introduction more than 50 years ago elisa enzymelinked immunosorbent assay remains one of the most widely used technologies for research drug discovery and diagnosis the reasons for this extraordinary longevity are manifold elisa combines the high specificity of antibodyantigen interactions with the high sensitivity of enzyme amplification however elisa also has disadvantages multiple washing steps and reagents are required and a specialized instrument is needed which is not always available in all laboratories an innovative immunoassay technology that can overcome the limitations of elisa while retaining all of its best features would therefore represent a turning point in the global immunoassay market 35 billion in 2023under the erc consolidator grant protoolkits we have developed a novel immunoassay which we have named enzymelinked dna displacement elidis which has all the characteristics to meet this need and become an alternative to elisa in short elidis involves 2 steps and is based on the use of enzymeconjugated dna strands and disposable electrodes elidis retains the advantageous properties of elisa high sensitivity and specificity but unlike elisa is easier to perform does not require enzymelabeled antibodies and more importantly can be performed using portable electronic devices such as a laptop or smartphone without the need for additional instrumentswith these considerations in mind in this poc project we will validate the elidis assay as a candidate to replace elisa in any biotech and biopharma laboratory to achieve the above goal we will 1 validate the elidis assay for the detection of two model targets trastuzumab and egfr 2 develop two prototype kits using disposable sensor arrays and a portable device or an appsoftware 3 create a manufacturing plan for assay production 4 develop an ip strategy for patent filingmaintenance 5 create a plan for businesscommercialization
support to retirement savings vehicle for european research institutions and research performing individuals resaver

the overall aim of the resaver pension fund as a significant development relevant for the social security of mobile researchers is to ensure free circulation of researchers by removing pension as an obstacle to mobility which corresponds to the strategic objectives of the union policy as stipulated in article 179 tfeu on the establishment of a european research areathis particular proposal aims to i internalize several management functions resulting in a more costefficient selfsufficient and leaner organisation ii directly contract the technical expert service provider currently contracted through the european commission and iii accelerate resavers growth through promotional outreach and dissemination activities since resaver became operational it showed that it can operate in an efficient and successful way in a large number of countries providing pensions at a low cost building on this success the most significant goal of resaver is now to strengthen own capacities and grow in size we will highlight a number growth objectives promotion implementation partnerships marketing sales support and awareness ranging among interested parties we will also build upon and connected to a previous grant httpscordiseuropaeuprojectid101056649 support to resaver pension fund horizon europe horizon europe widera work programme 20212022the more research institutions that join the resaver the more effective it will be in removing pensions as a barrier to the mobility of researchers in europe and the more it will fulfil its purpose of supporting the creation of a european research area allowing for a free circulation of researchers scientific knowledge and technology in execution of article 179 of the treaty on the functioning of the european union tfeu
100 households 100 circular stories inspiring sustainable living in europe

circleup is a highly innovative endeavor that aims to increase the diffusion rate of circular practices at the micro level as a vital step towards achieving a circular economy optimizing material streams into and out of households and closing the loops wherever possible it seeks to achieve goal by developing testing implementing evaluating disseminating an innovative behavioral intervention package consisting of consultation and information gamification and feedback approaches supplemented by a technical solution to provide this intervention package with this innovative behavioral approach the project will shape social norms by promoting communication and encouraging participants to question the status quo it will establish and foster the social identification of individuals as circular citizens inviting them to engage in and organize group activities that reinforce sustainable social norms and discourage unsustainable habits project will leverage an innovative technology tool to stimulate and channel interactions allowing participants to engage with people beyond their direct circle of neighbours or friends by sharing circular stories and participating in group activities participants will not only strengthen social bonds and satisfy the need for social connection and selfesteem interactive learning environments and simulation tools will support the transfer of insights and develop competencies for integrated analysis and modelbased assessments of key sustainable consumption policy and practice topics system dynamics modebased tools will support scoping and appraisal of strategies and policies related to sustainable consumption the success of this intervention package in 100 model households in four structurally and culturally different countries will demonstrate circleups potential to transform the way people consume how they can benefit from the circular economy and reduce social disparity environmental footprints ghg emissions
voices from the anthropocene maps and frameworks for ecological conflicts

the aim of the project is to develop an innovative framework for a better understanding of ecological crisis the current approach is based on the idea that we are going through a global crisis of nature however the anthropocene hypothesis a geological epoch marked by industrial activities shows that what we are facing is not a crisis of natural entities but a crisis of the concept of nature accounting for this semantic instability in ecological controversies allows us to see conflicts of representations where different social groups give voice to nonhuman entities our aim is to provide a transferable protocol to deal with that consisting in i deconstructing nontransformative rhetoric on environment
integrating breeding for ipm into the deployment landscape for wheat potatoes and grain legumes

ipmorama will improve the state of the art in varietycentric integrated pest management ipm for important diseases in the wheat rust pathogens potatoes blight and the grain legumes soybean pea broomrape and white lupin anthracnose ipmorama seeks to develop the infrastructure for a whole practice ecosystem whereby the more efficient development of ipmcentric varieties is enabled while at the same time developing tools and resources to efficiently exploit these in varietycentric ipm the core innovation of ipmorama is to integrate knowledge of host resistance with the pathogen virulence landscape over space and time to produce ipm tools eg crowd source apps vulnerability maps and strategies which will be validated at various scales and in conjunction with different agroecological practices ipmorama will achieve these goals by enacting the following five components 1 understanding the genetic composition of varietal resistance in target croppest systems and development of tools and resources to allow breeders to target the assembly of resistance components 2 understanding and mapping the landscape level distribution of the target pathogenspests especially in terms of their virulence against the available set of resistance and tolerance genes in varieties and breeding lines 3 developing specific integrated pest management practices for the optimal exploitation of pest and pathogen resistance in varieties on the basis of the first two components 4 developing the knowledge infrastructure for competent use of varietycentric ipm by actors across the varietyrelated value chain 5 understanding opportunities and barriers for scaleup of varietycentric ipm solutions
mediterranean and paneuropean forecast and early warning system against natural hazards

natural hazards such as extreme weather events are exacerbated by climate change as a result emergency responses are becoming more protracted expensive frequent and stretching limited available resources this is especially apparent in rapidly warming regions medewsa addresses these challenges by providing novel solutions to ensure timely precise and actionable impact and finance forecasting and early warning systems ews that support the rapid deployment of first responders to vulnerable areas specifically medewsa will deliver a sophisticated comprehensive and innovative paneuropeanmediterraneanafrican solution comprising a range of complementary services building on existing tools medewsa will develop a fully integrated impactbased multihazard ews this call contained five expected outcomes all of which will be specifically addressed by medewsa led by wmo medewsa will be an exemplar of the un secretary generals march 2022 call to ensure that everyone on earth is protected from extreme weather and climaterelated hazards by ews within the next five yearsthrough eight carefully selected pilot sites areas in europe the southern mediterranean and africa with a history of being impacted by natural hazards and extreme events with cascading effects four twins will be created twin 1 greece attica ethiopia national parks wildfires and extreme weather events droughts wind twin 2 italy venice egypt alexandria nile delta coastal floods and storm surges twin 3 slovakia kosice georgia tbilisi floods and landslides twin 4 spain catalonia sweden countrywide heatwaves droughts and wildfiresthe twins will bridge areas with different climaticphysiographic conditions yet subject to similar hazards and are well positioned to deliver longterm bidirectional knowledge transfer they will demonstrate the transferability and versatility of the tools developed in medewsa
accelerating transformative climate adaptation for higher resilience in european mountain regions

mountains cover 30 of the land area and are home to 17 of the eus population meaning that every 6th eu citizen lives in mountainous areas while we often associate mountains with breathtaking landscapes that offer perfect sites for relaxation in truth mountains are much more than that in fact mountains play a crucial role in our daily lives by providing vital resources and key community systems to the global population mountains like other areas face unprecedented challenges in terms of climate change cc however mountain ecosystems are more sensitive to cc the harmful conditions provoked by cc are exacerbated by the significant deficits in adaptation responses mountainous areas have stemming from several existing gaps including shortcomings in cca options deficits in the uptake and the lack of coherence mountresilience has been formulated to increase the adaptation capacity of mountainous regions and communities so as to strengthen climate resilience within the european mountainous biogeographical region alpine biogeographical region the project aims to accelerate the climate resilient transformation of 10 of the most relevant communities and regions located in the mountains in 9 european countries 6 of the regions will develop and test transformative cca solutions technological and social innovations with naturebased solutions at their core these solutions will address policy governance societal needs and behaviours technological requirements public and financing targets and cc risks typical of mountainous areas regional quadruplehelix partnerships will use open innovation participatory decisionmaking stakeholder engagement approaches and effective communication to mobilise engage and reach out to key communities the remaining 4 regions will serve as replicator regions repurposing cca solutions and lessons learned from the demo regions in their regions through special initiatives to improve their adaptive capacity
jwst alma dust enshrouded starformation in the spiderweb protocluster at the cosmic noon

the distribution of matter within the universe is defined by a complex multiscale interconnected network of filaments known as the cosmic web with galaxy clusters ie exceedingly dense regions residing at its nodes in the early universe z2 young forming clusters are observed as strong overdensities of gasrich dusty starburst galaxies becoming for a short time the dominant contribution to the star formation rate density before rapidly transitioning towards the massive quiescent population that dominates mature clusters only a few gyrs later however the accompanying large amounts of dust a byproduct of star formation heavily obscure such transformative processes challenging optical observations even with the hst and preventing us from obtaining an unambiguous view of stellar mass growth in early dense environments the jades project will overcome such obstacles for the first time by disentangling the starforming and dust components using deep and highresolution observations in the restframe nir and submillimeter regime traced by approved jwst and already available alma programs in the legacy spiderweb protocluster field at z216 in particular jades will be the first to establish a full census of starformation activities obscured and unobscured by using the dustfree pa star formation indicator jwst across the largescale structure of this protocluster jades will also trace the distribution of dustobscured starforming regions within previously identified subaru h emitters by making use of their pah ratio balmer decrement and it will map and weight the dust and molecular gas content within individual objects alma establishing a direct comparison between the starforming and dusty regions altogether jades will transform this field into the benchmark of environmental studies becoming the cornerstone of present and future numerical simulations investigating the formation of structure and mass buildup at this cosmic epoch
modular electrical generator pto system for wave mega pto wave

the world faces the challenges of transitioning to net zero emissions to combat climate change requiring a shift from fossil fuels to renewable energy sources like wave energy yet the integration of wave energy into the global energy mix is not without hurdles harnessing the power of ocean waves requires innovative and reliable technologies that can withstand the harsh marine environment while ensuring consistent energy generation moreover the pursuit of sustainable energy production extends beyond emissions reduction to embrace circular economies circular economies advocate for a holistic approach where resources are continually reused repurposed and recycled thus minimising waste and maximising resource efficiency for the wave energy sector this means not only developing efficient power takeoff systems but also considering the lifecycle impacts of materials manufacturing installation operation and decommissioning the mega pto wave project aims to provide an enabling technology to transform ocean waves into clean reliable energy through this project a smart scalable system will be created that adapts to changing conditions and keeps working even if a part of the system experiences a fault by designing all aspects of the mega pto to be highly modular incorporating novel axial flux magnetic gear electrical generator technology and adaptable power electronics the project will make energy production more efficient and ecofriendly this modularity creates a system that is easier to manufacture transport install maintain remove and recycle than alternatives the mega pto wave project brings together expertise from all over the eu to create a pto linked to sustainable supply chains to accelerate wave energy commercialisation to capture vast amounts of predictable energy in a sustainable and cost effective manner in order to meet eu netzero targets by 2050
feelthrough haptic feedback for augmented and virtual reality

virtual and augmented reality vr and ar often summarized as extended reality xr is moving from a niche product to a mainstream market due to recent advances in wearable sensing and display technologies powerful vr and ar headsets are commercially available even for the general public and promise to become even more miniaturized and cheaper in the coming years a myriad of important application cases ranging from gaming or shopping to immersive design and engineering or to telesurgery and virtual training demonstrate the large innovation potential of xr however todays technologies and applications for xr predominantly focus on the visual channel alone in contrast rendering the haptic feel of objects in xr is still mostly unaddressed although it is common knowledge that haptic perception is an essential part of how humans experience the world hence important for realism and immersion this project sets out to mature the crucial components needed for feelthrough tactile feedback in xr that can dynamically augment and alter the haptic feel of realworld objects surfaces and the human body our technology originates from the applicants erc starting grant interactiveskin where we developed the foundations for a new generation of bodyworn user interfaces which we call interactive skin our approach is unique in proposing computational design and rapid manufacturing of stretchable electronics as a means to customize onbody interfaces feelxr will enable tactile augmentation of the human body through a less than 35 m thin tactile interface for wearable computing which retains the natural tactile acuity similar to bare skin while delivering highdensity tactile output suitable for applications in tactile xr and onskin interaction as there are no moving parts we can expect our technology to be built much cheaper than current solutions that rely on motors or pneumatics at the same time being better suited for batterypowered usages
emoface

access to health quality education and decent work are among the sustainable development goals established by the un member states in 2015 a key indicator for these dimensions is the development of social skills for populations with deficits in social interaction developing social skills is an ongoing and necessary task to ensure the wellbeing and social inclusion emoface offers a solution with high social impact linking artificial intelligence technology and social skills developmentemoface is developing applications and training services to support autistic people throughout their lives our first application emoface playlearn emotions proposes playful activities in interaction with 3d avatars in order to train socioemotional skills such as recognizing the emotions of others out of and in context expressing and managing emotions and understanding the intentions of othersthe curriculum and visual content used to illustrate emotions and social situations are adaptable to the users needs so that our tools can accompany autistic people independently of their development and age our adapted design has been tested on nonverbal kids to adult autists with or without intellectual deficits our tools address both families and health practitioners allowing them to easily share information about the improvement in socioemotional skills using our methodology that proposes objective measures in order to facilitate skill evaluation and even prediagnosiswomen techeu program can help respond to the biggest challenges faced by emoface in short and midterm the activities i plan to support with the eu grant involve operational and strategic activities in relation to international development and validation of pathway to reimbursement plans the program would also benefit coaching from international mentors with various expertise and the access to networks of expertise for growth and expansion to international markets and busi
situationaware orchestration of adaptive architecture

the majority of workers express dissatisfaction with their shared workplace design which harms their health wellbeing productivity and social relations socalled adaptive workplace technologies try to manage these health risks by automating a wide range of architectural building services however there is severe lack of concrete evidence on how the short and longerterm impact of such adaptive architectural technologies on health and wellbeing can be objectively measured and then become benchmarked and optimized for a variety of hybrid workplace contextssonata therefore aims to generate evidencebased recommendations on the use of architectural adaptation as technological intervention that can benefit human health and wellbeing in the workplace firstly sonata aims to measure quantify and increase the range of health and wellbeing benefits of the separate and combined effects of stateoftheart architectural adaptations on four different building shearing layers secondly sonata will generate empirical knowledge on how these multiple colocated adaptations can be intertwined together so that their health and wellbeing impact is greater than the sum of the separate layers lastly sonata investigates how these positive effects can become equitably negotiated between the varying and often conflicting work situations that must coexist in a shared workplace to ensure the resulting recommendations are feasible easily adoptable and costeffective to implement sonata will involve the proactive participation and critical analysis from a wellconsidered selection of key target group representatives such as workers oshresponsibilities oem and ohp experts architects workplace organisation innovators adaptive technology manufacturers and building certification consultants
en fake news and conspiracy theories lets empower ourselves for science silane novice in teorije zarote opolnomoimo se za znanost

our society faces increasing challenges which the scientific community addresses by participating and contributing to various eu measures like horizon europe and its missions open science and many more but their efforts are often undermined by fake news circulating and growing in social bubbles and echo chambers fake news and conspiracy theories lets empower ourselves for science slovene acronym oooznanost english acronym oooscience is the red line of the 11th edition of the european researchers nights night ern project which now includes researchers at school activities under the coordination of the university of maribor which continues to engage the scientific community with various national and local media and primary and secondary schools the projects main objective continues to raise awareness of the researchers profession and reinforce their positive image the benefits that scientists create for society to stimulate curiosity and skills to detect fake news misrepresentation and fabrication of scientific resultsfacts and find reliable information through open science and last but not least to inspire the young to embark the research profession those as mentioned earlier will be pursued by the researchers involvement in the intensive awareness campaign numerous edutainment activities in festive spirit during the european researches nights 2024 and 2025 maribor koper izola active involvement of our researchers in schools in many slovenian cities and strengthening researchers competencies and communication skills to interact with the nonresearch audience effectively and followed by improved indepth impact assessment studies