Dragon09/odtu_chatbot huggingface dataset:
supporting stakeholders for adaptive resilient and sustainable water management

worldwide freshwater resources are under increasing pressures of rapidly intensifying climate change effects putting the availability and quality of water resources and socioeconomic developments at risk river basin organisations need to be prepared stars4water aims at improving the understanding of climate change impacts on water resources availability and the vulnerabilities for ecosystems society and economic sectors at river basin scale stars4water will develop and deliver new data services and datadriven models for better supporting the decision making on planning on actions for adaptative resilient and sustainable management of fresh water resources the project team will work with seven river basin organisations through a cocreation living lab approach the new services and models will be codesigned with stakeholders to meet their needs on data and information ensuring relevance and uptake for use beyond the lifetime of the project the stars4water project includes two distinctive elements first the need for an international stakeholder community to address the stakeholders needs and requirements and second the development and application of innovative data and model concepts new datasets and models offer possibilities for improved projections on water resources availability and the new insights on links between water nature society ask for a broader set of indicators to be considered in decisionmaking on water management these novel datasets models and indicators are not yet fully matured and integrated in current river basin management information tools and decisionmaking processes we acknowledge that these elements are of a different nature being a stakeholderdriven approach and rather sciencedatadriven in the application of novel data and models respectively it is the consortiums firm conviction that for substantial progress in climate change adaptation the two elements need to be combined
nad international scientisttraining

nicotinamide adenine dinucleotide nad is a central redox cofactor and the limiting substrate of key metabolic enzymes the constellation of cellular functions in which nad is involved makes its availability critical for cell survival and its depletion is a leading factor in a number of diseases in humans ranging from rare inherited defects to more common multifactorial often agerelated complications including type 2 diabetes neurodegenerative diseases and female infertility in contrast nadrepletion strategies such as administration of nad precursors may be effective in preventing or ameliorating the outcomes of these complications nadis partners have made pivotal discoveries in the field of nad biology first by discovering novel mechanisms linking nad metabolism to prevalent diseases such as type 2 diabetes cancer cachexia alzheimers parkinsons or rare inherited mitochondrial disease and to lifespan regulation second by identifying lifestyle nutritional and drug interventions that target nad metabolic pathways to combat such diseases and promote healthy aging despite these recent advances there are still major gaps in our current knowledge in regard to 1 how nad homeostasis is regulated at different stages in life 2 how its imbalance leads to disease at a systemic level and 3 which nad repletion strategy is the most suitable to prevent or treat specific diseases it is the ambition of the nadis consortium to fill these gaps by training the new generation of early stage researchers esrs on how to apply stateoftheart tools to study the interconnection between metabolic cofactors such as nad and metabolic health at different levels and to provide them with an interdisciplinary and intersectoral training programme that significantly increases their career perspectives and allow them to become future leaders in the field of translational metabolism
a novel test trio to detect peptide biomarkers in saliva and blood for enhanced diagnosis and management of alzheimers disease

fluidxad aims to transform alzheimers disease ad diagnosis and prepare the eu healthcare systems for the emergence of new ad therapies with a 1stinclass trio of in vitro diagnostics testsfluidxad tests detect a unique and proprietary suite of biomarkers in simple bodily fluids saliva plasmablood towards widespread patientempowering and allinclusive ad diagnosis at least as accurate as the costly and invasive procedures currently in placefluidxad tests have the potential to shorten ad diagnosis by 715 years by detecting biomarkers that mark the onset of ad years before the appearance of clinical symptoms earlier diagnosis means earlier access to preventive interventions which are now more effective thanks to nextgeneration immunotherapies the clinical use of these new drugs is not consensual though because of the severe sideeffects they inflict in some patients fluidxad tests offer a pioneering tool to stratify and monitor patients eligible for these drugs towards reducing their associated risk and accelerating their regulatory clearance in the eufluidxad tests are thus devised to work complementarily and sequentially covering the full ad diagnostic journey from populationwide screenings to confirmatory diagnosis and downstream patient stratification and monitoring tackling key challenges of early ad diagnosis and ad prevention with new drugs while also paving the way for the development of new therapies by streamlining patient selection and appraisal in clinical trialsfluidxad brings together a team of highly motivated committed and reputed entrepreneurs clinicians and scientists from biotechs hospitals academic centres and patient organizations across the eu leveraging our unique blend of transdisciplinarysectoral expertise and access to advanced technologies and infrastructures we join forces to realize the vision of a new era of ad clinical management for the benefit of millions of patients globally
a cryptosporidiosis pointofcare testandtreat strategy in children with diarrhoea

cryptosporidium is an intestinal parasite causing cryptosporidiosis a prevalent diarrheal disease among young children in low and middleincome countries this infection causes approximately 48000 deaths and the loss of 79 million disabilityadjusted lifeyears annually despite the existence of a lowcost drug access to treatment is hindered by the limited availability of affordable straightforward pointofcare poc diagnostic tests led microscopy of auraminephenol ap stained fecal smears has demonstrated promising diagnostic accuracy in detecting cryptosporidiosisin this project we will implement a testandtreat strategy in a steppedwedge cluster randomized trial the aim is to assess the clinical effectiveness of ledap testing in conjunction with access to targeted drug treatment in reducing the duration of cryptosporidiosisinduced diarrhea we will evaluate diagnostic accuracy operational issues costeffectiveness and test turnaround times in realistic setting in two subsaharan african ssa countries additionally we will investigate whether rectal swab samples can expedite test turnaround times compared to bulk stool samplesthis project aligns with the un sustainable development goal 3 and who initiatives to reduce the burden of diarrheal diseases effective poc diagnostics and treatment are expected to alleviate diarrhea and reduce longterm complications the findings will be instrumental in updating current diarrheal treatment guidelines which primarily advocate for syndromic treatmentthe outcomes will be of significant interest to health facility staff ministries of health in ssa who and the scientific community this study will provide crucial data on optimizing ledap testing to guide clinical decisionmaking and targeted treatment thereby preventing the overuse of antibiotics the introduction of cryptosporidiosis testing can enhance surveillance of this critical pathogen
mwgaiadn revealing the milky way with gaia

the milky waygaia doctoral network mwgaiadn revealing the milky way mw with gaia excellent science extending techniques enhancing people skills effecting the next revolution in european led astronomy through leadership in astrometricbased science what gaia esas major space mission launched in dec 2013 is now in its extended mission to map some two billion stars in the mw its upcoming data releases that will provide chemical and physical annotation of the earlier positional releases present major challenges in terms of complexity and size hence research training to deliver a full science exploitation is essential ensuring that gaia is the game changer for astronomy how our dn will link major partners responsible for the development of gaia to form an effective and unique training network combining the best research training with a range of academic and industrial placements specialist research and knowledge transfer workshops it will develop and train a cohort of young researchers through a set of key science projects pushing the gaia data to its limits our dn will train 10 esrs located across 10 european beneficiaries benefiting from the participation of 13 associate partners these include major industry eg airbusds tas at the forefront of space and information technologies sme industry eg dapcom suil innovating new technologies for space and partners leading the development of next generation astrometry missions outside of europe naoj relevance it will shape the delivery of training in astrometry and the study of the mw across europe delivering key insights into the structure and formation of our galaxy delivering the roadmap for the next generation of astrometric space telescopes equipping the esrs with skills to drive the next innovative steps in this crucial area of space discovery as well as enabling them to contribute to the future growth and challenges of the big data industry and commerce mwgaiadn
a new xray pulsar navigation system for deep space exploration

the deepspacepulse project aims at studying the viability of an autonomous pulsar xray navigation unit that will improve by an order of magnitude almost all aspects of previous similar systems making these satellite positioning devices competitive in both the public and private space market pulsars are astrophysical objects namely the final result of the supernova explosions of very massive stars we have detected thus far about three thousand pulsars in our galaxy but we know this is only the tip of the iceberg of their entire population pulsars are perfect clocks with unprecedented stabilities making them a perfect gps system in space the deepspacepulse pulsar navigation system is expected to be an efficient small and light navigation unit to be mounted in future space missions this novel navigation technique has been recently tested on the international space station and can be used within our own solar system reducing costs with respect to more standard positioning systems but also for future deepspace navigation travelling in deepspace is currently limited by the required power to exchange information with earth in particular concerning the satellite positioning system and orbit determination the first step for a future deepspace exploration is to develop the technology that will allow any space mission to be able to guide the spacecraft autonomously deepspacepulse using this erc poc lump sum wants to perform a feasibility study for a new concept of an autonomous xray pulsar navigation system expected to weight about 10kg be as big as a microwave oven and using a new pulsar observation plan that will possibly permit to keep the satellite autonomous positioning stable for a few centuries
cams aerosol advancement

the european unions flagship space programme copernicus provides a key service to the european society turning investments in spaceinfrastructure into highquality information products the copernicus atmosphere monitoring service cams httpsatmospherecopernicuseu exploits the information content of earthobservation data to monitor the composition of the atmosphere by combining satellite observations with numerical modelling by means of data assimilation and inversion techniques cams provides in nearreal time a wealth of information to answer questions related to air quality climate change and air pollution and its mitigation energy agriculture etc cams provides both global atmospheric composition products using the integrated forecasting system ifs of ecmwf hereafter denoted the global production system and regional european products provided by an ensemble of eleven regional models the regional production system the cams aerosol advancement camaera project will provide strong improvements of the aerosol modelling capabilities of the regional and global systems on the assimilation of new sources of data and on a better representation of secondary aerosols and their precursor gases in this way camaera will enhance the quality of key products of the cams service and therefore help cams to better respond to user needs such as air pollutant monitoring along with the fulfilment of sustainable development goals to achieve this purpose camaera will develop new prototype service elements of cams beyond the current stateofart it will do so in very close collaboration with the cams service providers as well as other tier3 projects in particular camaera will complement research topics addressed in cameo which focuses on the preparation for novel satellite data improvements of the data assimilation and inversion capabilities of the cams production system and the provision of uncertainty information of cams products
shielding food safety and security by enabling the foresight of fungal spoilage and mycotoxins threats in the mediterranean region under climate change conditions

the overall aim of the funshield4med project is to strengthen the scientific excellence and innovation capacity of the institute of technology of agricultural products itap of hellenic agricultural organisation dimitra elgodimitra from greece in the field of food safety against mycotoxigenic spoilage fungi and mycotoxins under climate change challenges the strategic collaboration of advanced partners from italy university of parmadept of food and drug spain university of lleidafood technology dept and uk cranfield universitysoil and agrifood institute and an internationallyleading university from greece national kapodistrian university of athensdept of chemistry will ensure the knowledge and expertise transfer help build new research alliances and enrich apart from institutes personnel as well as young researchers capacities from all members of the consortium in order to achieve the twinning calls specific objectives the consortium of funshield4med will implement a comprehensive set of measures and activities such as short term staff exchanges and expert visits training workshops seminars summer schools and dissemination and outreach activities in addition to the specific objectives of twinning a comprehensive research project is foreseen focusing on mycotoxigenic spoilage fungi and mycotoxins in relation to one main eu entry point greece for imports from the south and east african and asian countries to facilitate appropriate surveillance of commodities where mycotoxin contamination may increase because of climate change cc factors this will minimize exposure of consumer to these toxins and will provide benefits in traceability of both emerging and modified forms of mycotoxins in staple food and drink chains in the context of cc scenarios
chalcogenidesilicon tandem pec for co2 reduction

solar driven photoelectrohemical reduction of co2 co2r to valuable chemicals and fuels in artificial photosynthesis is of high importance for sustainable future and societal growth among current pec systems electrolysis from pv cells using iiiv semiconductors is promising but high material cost is a major limitation integrated pvpec systems are desirable however they suffer from low performance due to insufficient solar spectrum utilization carrier generation and transport losses and poor catalysis an efficient and lowcost integrated system of a photocathode pc and photoanode pa is yet to be realized for simultaneous co2r and oxidation of alcohol or water respectively in this project we propose a tandem architecture including monolithic and wired connected design comprising of 18 20 ev bandgap cuingas2 based top cell pc and silicon 11 ev pa as bottom cell the photovoltage of 18 ev is targeted from cigssi tandem system this will be accomplished by synthesizing highquality cigs optimized for interface recombination coupled with nanostructured and dual side doped si the key aspect of the project is to couple the co2r with the glycerol oxidation reaction which lowers the voltage requirement and makes it feasible for biasfree operation of co2r and glycerol oxidation thus producing valuable products like co and formic acid at pc and pa respectively pc and pa will be individually optimized for high voltage carrier selectivity light management high surface area catalysis and protected surfaces to avoid degradation the design of the project allows to investigate device with electrical bias similar to 3terminal tandem pv device separate pc and pa reaction chamber will make product separation easier with accurate estimation of the fuel production efficiency applied bias light intensity light wavelength and catalyst coating layer will be varied and its relation to device performance and degradation will be established
the chemical exposome in pregnant women and metabolic dysregulations analysis towards the prioritization of hazardous chemicals

expoisomics is an interdisciplinary and highly innovative project in the field of human exposomics and bioinformatics the main objective of expoisomics is to obtain a holistic picture of both the external and internal chemical exposome in a large cohort of pregnant women to study which are the contaminants that can cause metabolic alterations once we know which contaminants are having more effects we will develop new cheminformatics tools capable to predict the chemicals with potential to dysregulate human metabolism based on insilico predicted molecular predictors expoisomics will analyse samples of blood and urine of 200 pregnant women residents in greece from the rhea cohort this project will use stateoftheart instrumentation to provide nontarget data at trace levels from a vast chemical domain obtaining with the same data information of both contaminants presence external chemical exposome and specific alterations in the endogenous chemical profile internal chemical exposome by means of target suspect nontarget and metabolomics strategies expoisomics will also be pioneer in developing cheminformatics tools to predict when a certain chemical may represent a problem to human health for the development of the tool experimental data from this project will be joined with others cohorts results in which the applicant is currently involver and the principal investigators have agreed to share eg bisc httpswwwprojectebiscorg and insulin httpswwwtecnatoxcatlistofprojects for validation purposes the expert knowledge of fellow and host group gives the security to reach the ambitious objectives
aid from islamic donors in conflict zones

islamicaid has the overall objective to provide a broader understanding of humanitarian aid in conflict zones as implemented by islamic actors and improve the dialogue between western and gulf donors the action has two specific objectives one is related to islamic social welfare instruments and their contribution to social protection and economic empowerment the second concerns the foreign aid of saudi arabia qatar and the uae and the implementation through different channels including charity organisations these two objectives will consider interventions in three conflict zones such as yemen sudan and syria from 2015 to 2022 the necessity to enhance the coordination of aid interventions and expand the resource base for humanitarian financing makes this research relevant in terms of timing and scope the action aims to contribute to the dg echo humanitarian logistics policy which promotes effective coordination with other humanitarian organisations in complex crises not only does the research fill the gap in the literature but it also analyses aid practices from a topdown and bottomup approach with an anthropological perspective through fieldwork and ethnographic research which will produce new evidence of islamic financing instruments gulf donors decisionmaking process and everyday humanitarian negotiation practices of organisations in the field through the collaboration between unive and princeton university and the supervision of prof legrenzi and prof haykel the msca will allow me to expand my previous study on islamic aid practices receive training in anthropology ethnographic research and social network analysis and become an expert in gulf donors and humanitarian financing in conflict zones i will productively engage with the us academic circle acquire new knowledge and expertise bring it back to europe and ultimately build my future academic career in europe with strong networks in the gulf states and the us
prototypes for addressing the housingenergynexus

european societies are confronted with an interlinked housing and energy crisis that is challenging social cohesion as access to affordable housing becomes limited inflation and accelerating energy prices pinpoint that energy poverty and housing inequalities mutually reinforce within this context the deep renovation of the existing housing stock is promoted as key policy action however despite policy efforts from the eu to the local state there are growing concerns that the transformation of housing markets may further aggravate the existing housing inequalities and energy poverty to offer more equitable pathways to the green transition prefigure puts the spotlight on existing and emerging individual and collective efforts of policy market and social innovation the project aims at identifying tracing analysing and networking emerging and active prototypes of change with regard to the housingenergy efficiencyenergy poverty nexus research objectives are to i offer understanding of how practices of innovation contribute to affordable housing renovation schemes that disrupt existing housing inequalities and energy poverty ii identify how housing policies trigger sustainable housing and energy transitions how financial incentives for energyefficient buildings are accessed by different types of owners and tenants and how different user groups perceive sustainable housing and energy transitions with a particular focus on income and wealth polarisation consequences on vulnerable groups and iii mobilise knowledge about innovative practices for sustainable housing and energy transitions and cocreate evidencebased policy solutions method innovation relies on fusing transformative qualitative and quantitative with technological and reallaboratory research to cocreate and upscale knowledge and practices that signal the green transition