Dragon09/odtu_chatbot huggingface dataset:
constraining dense nuclear matter with the dynamical tides of neutron stars

the discovery of a merging binary neutron star in 2017 gw170817 marked an historic moment in the field of astronomy this groundbreaking observation witnessed by both electromagnetic and gravitationalwave instruments unveiled a wealth of scientific insights while capturing worldwide public attentionneutron stars with their extraordinarily dense interiors are natures laboratory for dense nuclear matter about which very little is currently known while in the past electromagnetic observatories have been the primary sources of neutronstar observations the emergence of gravitationalwave astronomy epitomised by gw170817 has introduced a novel dimension to the observational effort the forthcoming generation of gravitationalwave interferometers will possess even greater sensitivities but their scientific impact will rely on meticulous design choices along with the development of advanced dataanalysis methods and robust physical models this proposal dyntideeos will address these critical needs and contribute to the science capability of these instruments at a critical time for design decisionsdyntideeos considers the dynamical tide which drives the oscillation modes of the neutron star when the binary is closely separated this project will identify the dominant modes in the gravitational wave extract valuable constraints on the nuclearmatter equation of state and pioneer a stateoftheart gravitationalwaveform model for the dynamical tidedr fabian gittins with his outstanding background in theoretical astrophysics joins forces with prof chris van den broeck a worldleading expert in gravitationalwave observations at utrecht university dyntideeos not only promises original contributions to neutronstar astrophysics and gravitationalwave astronomy while setting the stage for rich insights into nuclear physics but will also underscore dr gittinss research excellence with a strengthened connection to observational physics
innovative applications of assessment and assurance of data and synthetic data for regulatory decision support

insafedare aims to provide a toolkit to enable costeffective and high assurance decisionmaking in the context of the processes that all stakeholders may follow as part of regulation of medical devices the toolkit consists of scientific guidance on assurance tools to retrieve datasets and assist application validation and a publicly available guidance workgroup for sustainable support of the discipline insafedare will investigate use challenges and opportunities real world and synthetic datadriven validation of devices the project will provide guidance on quality and safety assurance of datasets as a tool for validation and devices that have validated using data driven approaches insafedare will investigate use of synthetic datasets and will identify how they can be used to establish assurance before the formal established certification process reducing the risk for developers and waste for regulatory bodies furthermore the project will publish the findings as a public guidance laying the ground for a standard development working group and develop training and syllabus that can enhance the skills of stakeholders finally the project will develop a tool for the discovery integration and query of multiple datasets and a tool for supporting the sustainable dynamic and throughlife surveillance of devices capturing the impact of new evidence offered by newly published datasets
circular sustainable textiles clothing

cisutac will tackle current bottlenecks in the transition to circular textiles and clothing for scale and significance we focus on polyester cotton cellulosic fibres together ca 90 of textile materials and products from 3 subsectors garments active goods and workwear in this way we will have a representative view on the challenges the textile sector is facing for circular transition cisutac follows a holistic approach covering the technical sectoral and socioeconomic levels we will provide systemic innovations at these levels and perform 3 pilots to demonstrate their feasibility and value i repair and disassembly ii sorting for reuse and recycling iii circular garments through fibre to fibre recycling and design for circularity to realise these pilots we will develop semiautomated workstations analyse infrastructure and material flow digitally enhance sorting operations and setup interventions with consumers after the piloting phase attention will be on the uptake of the results by the sector by the wider stakeholder group as well by the consumerswith worldwide leading brands and companies csos rtos and eu associations cisutac is truly euwide and covers the full novel circular value chain through the consortium and further supported by the transition support group with zz members cisutac is strongly linked to ongoing initiatives allowing synergies and joint activities this is essential for our implementation but also for leveraging the impact and enabling the shift towards a sustainable eu textiles clothing underpinned by circular material flows and supported by the wider stakeholders cisutac will bring significant impact of scale via its innovations on repair dismantling sorting and fibretofibre recycling realising this impact will lead to a reduction of ca 975ktonco2eq yearly and to new business activities and markets that together have a value of ca 250mio and lead to ca 1300 fte also social economy
closing the gap between fork and farm for circular nutrient flows

p2green will foster a paradigm shift from a linearly organised resource and nutrient system within the agrifood supply chain towards a circular material flow system between urban and rural areas thereby restoring the coupling of the wateragrifood system using a holistic symbiotic resource management approach following the 3r principle reduce reuse recover p2green will therefore develop new circular governance solutions for the transition from fork to farm to halt and eliminate n p pollution by connecting blue urban with green rural infrastructure focussing on circular nutrient flows of nitrogen n and phosphorus p this will be done trough implementation and demonstration of innovative n p recovery solutions for the utilisation of human sanitary waste from urban settlements and its conversion into safe biobased fertilisers for agricultural production in three pilot regions p2green pilot regions on a northsouth trajectory from the baltic sea region via the metropolitan area of hamburghannover to the region of axarquia in southern spain this approach will be extended to follower region in italy france greece and hungaryp2green will close nutrient cycles of n p to foster the transition towards a circular and clean economy green transition as well as supporting sustainable food systems from farm to fork offering viable alternatives to reduce the current usage of mineral fertilisers with innovative green biobased fertilisers and thus minimise the pressure on the natural resources specifically water and soil p2green will further enable policy makers to replicate p2greens sustainable regional circular economy models in all regional settings across europe to facilitate systemic change cocreation strategies including the participation of all relevant stakeholders as well as harmonised governance frameworks that foster innovations will be key to p2green
omi ai ecg model application for more accurate heart attack diagnosis

globally 50m patients with chest pain present to emergency departments each year in these patients a 12lead electrocardiogram ecg serves as a swift and readily available diagnostic test for identifying acute obstructive heart attacks omi a lifethreatening condition that requires prompt transfer to a cardiac catheterization laboratory the omi ai ecg model is an aipowered mobile application that can process any ecg and diagnose omi faster and more precisely than current stateoftheart criteria according to which 50 of omi cases are missed or delayed in treatment this technology combines a patented ecg digitization system converting any paperform or screenbased images of ecgs into standardized digital waveforms and an ai algorithm trained by physician experts with 50 years of experience in omi diagnosis from ecg who established the omi paradigmit is immediately applicable doesnt require additional hardware and works with any healthcare infrastructure in a large international validation of over 2000 patients it has proven to be twice as sensitive as the current standard of care in diagnosing omi and can detect it 29 hours faster due to more accurate and faster diagnosis this solution will cause a paradigm shift in heart attack patient management saving millions of lives and decreasing the economic burden of cardiovascular disease
biomarkers affecting the transition from cardiovascular disease to lung cancer towards stratified interception

cardiovascular disease cvd and lung cancer lc are leading causes of deaths and intertwined chronic inflammatory processes associated with metabolism reprogramming clonal hematopoiesis of indeterminate potential chip intestinal dysbiosis and maladaptive immunity cvd pronetobacco users exhibit a 12 yearly incidence of lc low dose computed tomography screening programs reduce lc mortality by 20 beyond epidemiological scores risk identification early cancer detection and interception are mostly based on cell autonomous approaches understanding pathophysiological failures linking cvd to lc would allow to take steps for prevention based on metabolometagenoproteoimmunogenomics our prevalung prospective study conducted in cvd tobacco consumers allowed to unveil four drivers of early carcinogenesis leading to actionable biomarkers that can be harnessed to pioneer personalized interceptive measures four main objectives will be harnessed by 7 academic partners transdisciplinarity and trialists in interception 3 diagnostic biotech cies and one nutrition foundation first refine and validate in retro and prospective cohorts 60000 the 4 classifiers relying on the 4 inflammatory drivers autophagyinnate immunityintestinal barrier defects and chip to implement patient stratification second develop and validate robust friendlyuser tools monitoring such biomarkers for routine risk assessment third demonstrate the actionability of these biomarkers through a biologicallyinformed multiarm randomised trial testing measures targeting each of the 4 main drivers of inflammation using food supplements or pharmacological agents metformin antinkg2apdl1 abs il1 inhibitor probiotics respectively in addition to diet and lifestyle changes to return to homeostasis fourth to adapt a secured interface between patients and clinical researchers using these new tools to the longitudinal monitoring of the interceptive measures
integrated oxycombustion solutions for flexible biobased combined heat and power a negative emissions technology for a netzero europe

combined heat and power chp is a highly efficient method for cogenerating electricity and heat with biomass feedstocks chp can be considered a renewable source the capture of co2 from biomass chp presents an opportunity for carbon removal aiding europes journey toward negative emissionschallenges including supply logistics feedstock sustainability and competition with other renewables like wind and solar must be overcome to achieve costeffective lowemission and decarbonized chp from solid biomass residues additionally issues like feedstock handling combustion efficiency emissions nox sox particles and economic feasibility hinder market development the bionetzero projects objective is to significantly advance three oxycombustion technologies oxymild clc and oxycfb the project addresses these technical challenges through realworld testing modelling and the development of precise digital tools comprehensive regional showcase studies conducted by bionetzero encompass technological social environmental and economic dimensions these advancements seek synergies with oxygen supply solutions such as cryogenic methods alignment with the hydrogen economy and utilization of solid oxygen carriers integration with flue gas cleaning and co2 conditioning processes facilitates carbon removal enabling the realization of nearly zeroemission biomass heating and biomass chp systems including carbon capture one of bionetzeros advantages lies in its regional focus recognizing that deployment obstacles often arise at local levels the project will assess its suite of solutions in regions in transition across europe and propose novel solutions for next generation chp plants
mitigating antimalarial resistance consortium in southeast africa

background gains achieved in reducing the burden of malaria and advancing its elimination are now threatened by the independent emergence and local spread of artemisininresistant parasites in east africa protecting the efficacy of the current firstline malaria treatments all of which are artemisininbased is now a top public health priority objective the mitigating antimalarial resistance consortium for southeast africa marc seafrica is designed to promote the translation of evidence of artemisinin and partner drug resistance of public health significance into policy and practice methods marc seafrica brings together clinical researchers with experience in implementation research experts in malaria chemotherapy and health policy national malaria programmes and end users together we will improve estimates of antimalarial drug resistance and codesign a costed regional detailed action plan to respond promptly to emerging antimalarial drug resistance dynamicallyupdated evidencebased malaria treatment guidelines and graphic evidence summaries using magicapp will be developed disseminated and evaluated expected results predictive maps will better define antimalarial drug resistance for all eighteen southeast african malariaendemic countries we will expedite evidence sharing on antimalarial drug resistance with policy makers in at least eight countries we will help at least four countries respond promptly and effectively to these results we will facilitate the use of evidence on antimalarial resistance to inform better malaria treatment policies and will evaluate their uptake into clinical practice by primary healthcare workers in at least two countries this will provide an evidencebased reproducible model to mitigate the threat of antimalarial drug resistance and ensure sustained effective malaria treatment including for the vulnerable communities that bear a disproportionately high burden of malaria and its suboptimal treatment
transforming molecular diagnostics through nanotechnology

biotechnology startup altratech ltd was founded with the vision to transform molecular diagnostics through nanotechnology wehave developed and patented a novel technology for molecular testing of viruses and pathogens in nonclinical environments thisallsynthetic novel assay can detect and quantify dna rna antibody and antigen molecular targets from blood or saliva samples in20 mins without any need of centrifuges or pipettes this will enable marketdisrupting products that have the simplicity of apregnancy test and the performance of a laboratory pcr testall molecular diagnostic systems today require biological amplification ie polymerase chain reaction pcr loopmediatedpolymerase amplification lamp or similar this takes time and requires trained personnel refrigeration for enzymes and specialisedequipment for heatingcooling and optical detection it is because of these requirements that there is no solution on the markettoday for the nonclinical detection monitoring and management of viral infections such as hiv hepatitis influenza malariameningitis shingles dengue fever hpv ebvrelated cancers and many moreour solution is a molecular detection process that eliminates the requirement for biological amplification and optical detection wehave invented and patented the key breakthrough of detecting and quantifying genetic material viruses and pathogens usingalmost instant electronic signal amplification with semiconductor sensing and digital readoutthe value proposition to our target customers who will be the worlds leading diagnostic companies is the ability to licence a novelpatent protected product with a wider range of market applications compared to their current diagnostic products this willfacilitate their entry into new markets and increase gross margins in existing marketsthis innovation will impact the 48b diagnostics industry
european lighthouse of ai for sustainability

we live in a crucial historical moment with tremendous challenges ahead from climate change to the energy crisis elias emerges from the belief that ai will be a key discipline to help us tackle these challenges at the same time the development of ai entails deep ethical and societal concerns that need to be addressed as for fundamental research elias will address key scientific questions about how ai can reduce computational costs serves to model effects of policy decisions on society and impacts individuals elias will strive for a deep integration of the fundamental research that takes place in academia and the more applicationsfocused research from industry elias builds on and expands the highly successful and internationally recognized europeanlaboratory for learning and intelligent systems ellis elias will further develop the excellence criteria and the pillars in ellis and implement actions that will support ai researchers and young talents at different stages of their careers furthermore elias will develop a sciencentrepreneurship track with the purpose of attracting and empowering talents at the interface of scientific innovation and business and establish original ai solutions that move towards a sustainable longterm future for our planet contribute to a cohesive society and respect individual rights the outcome of elias will be to establish europe as a leader in ai research in which impact on the environment society and the individual are integral considerations during development we will measure the success of this endeavor in terms of key indicators including the number of new crossinstitutional collaborations the number of crossdisciplinary collaborations the number of industryacademic partnerships publications in top conferences and journals patents and the number of projects that have resulted in deployed technologies
ye wha class gender race and age fixing diversity in texttospeech accessibility readers

title ye wha class gender race and age fixing diversity in texttospeech accessibility readers abstract ye wha is a creativecritical multidisciplinary project researching normative digital voice and developing alternatives research into voices used by chatbots accessibility programs and texttospeech readers in englishspeaking digital technology shows narrow representation in terms of gender race age class and regional accent with most voices presenting as young white rp received pronunciation and middleupper class prompted by research into the negative impacts of underrepresentation ye wha will use practicebased research to achieve three outcomesi will develop an opensource webbased texttospeech reader app using an alternative range of voices in terms of gender age class race and regional accent for freely available practical and creative use in collaboration with my industry secondment partner promising troublecareful industriesi will produce a creativecritical monograph furthering the autotheoretical techniques i have successfully employed in previous awardwinning projects delineating my research considering issues of representation and reflecting on voice technology and selfdrawing on my previous practical and theoretical investigations into the postmedium and hybrid practice a key aspect of my project will be to develop extend and evaluate methodologies that draw together creative research social interventions and critical writing bringing the fields of art academia and social practice into conversation via the creation of a presentation that will allow the exhibition of the app and monograph as an art piece in a range of settings online galleries conferences festivals and bookshops will create a positive interdisciplinary feedback loop as well as ensuring that my project has high cultural social and academic impact ye wha is an irishdublin colloquialism you saiddid what
integrated sensing localization and communications in 6g thz systems

in parallel to the evolution of 5g communication systems 6g concepts are being developed in the academic community in 6g several key technical enablers are envisioned i mmwave and thz frequencies electromagnetic with extremely large bandwidths and extremely large antenna arrays ii reconfigurable intelligent surfaces that control the propagation environment and iii machine learning to solve problems for which mathematical models are not sufficient as locationaware communication ie to optimize network efficiency and communication capacity by exploiting location map and trajectory information is already a part of 5g we expect that the 6g key enablers will also lead to highaccuracy sensing and localization and in turn improve communication quality the goal of this project is to develop integrated sensing localization and communication systems for 6g and the project comprises the following 3 work packages wps in wp1 joint parameter estimation methods for the 6g channel are studied and lowcomplexity methods will be developed based on the inherent high resolution of the 6g channel by exploiting the estimated channel parameters of 6g signals novel methods for estimating user state as well as sensing the timevarying propagation environment will be developed in wp2 we will design methods to use sensing and localization information from wp2 for initial beam search beamspace processing beam alignment and power allocation in wp3 in doing so we address several of the fundamental challenges in 6g communications and highaccuracy sensing and localization
escape from upheavals evolutionary potential of migratory plasticity facing climate changes

critical ambitions in evolutionary ecology are to understand how wild species will respond to climatic and environmental upheavals caused by anthropogenic impacts populations are postulated to respond to changing environments through phenotypic plasticity or microevolution in situ or by moving elsewhere yet the ways in which these responses could interact potentially generating rapid microevolution of plasticity in movements have scarcely been considered hence full responses of mobile populations to rapid environmental changes cannot yet be predicted impeding population managementin plastmig i will break new ground in the nascent field of evolutionary movement ecology by providing first estimates of1 environmentallyinduced plasticity in seasonal migration thereby bringing new insight on environmental sensitivity of movement underlying population dynamics and distributions2 quantitative genetic variation underlying such plasticity hence providing new understanding of the potential for rapid microevolution of environmentallyinduced movementsi will achieve these ambitious objectives by extending and applying advanced quantitative genetic statistical analyses to an exceptional multiyear dataset on freeliving european shags available data comprise yearround field observations and pedigrees for numerous migrant and resident individuals experiencing varying environments allowing quantification of all key effects i will work in a leading international centre of excellence ensuring outstanding scientific and career developmentsplastmig will thereby achieve the threefold challenge to have important scientific impact by providing new conceptual and methodological advances linking evolutionary and movement ecology crucial societal impacts by laying key foundations for innovative conservation strategies for migrant species and personal impacts through exceptional career training making me a leading international researcher