Dragon09/odtu_chatbot huggingface dataset:
everglass the new role of glass in a sustainable society technology for the integral recycling of glass

glass recycling uses mature technology limited by high energy consumption to melt tons of glass and the inflexibility of a heavyduty system current technology only allows the recycling of certain glasses and a very small amount of waste generated a new technology is required to allow the integral recycling of all types of glass drastically reducing the carbon footprint everglass proposes to develop a radically new technology called glass laser transformation for onsite glass recycling and the generation of customized or technical products users will feed waste into a new machine and select which new product to get the vision is ambitious as it aims to bring to the consumer market a novel technology to enable virtually infinite reuse of glass it is also radical since through a multipurpose system capable of being located on any site it proposes an alternative approach to the traditional centralized recycling process particularly where this model is not possible generating thousands of tons of glass waste annually taken to landfills the new technology goes beyond the current limitations of the systems high energy use expensive and rigid process strong logistical requirement adopting a highly environmentally friendly model that will allow flexibility in the use of the material and in the process therefore everglass has the potential to revolutionize recycling as a concept it also addresses one of the main problems with recycling user participation in an innovative way by allowing the personalization of recycled items of different use finally it aims to encourage the use and reuse of glass as a quality material displacing more environmentally problematic materials such as plastics this project brings together experts from advanced laser technologies uvigo glass and ceramics science icvcsic glass processing and engineering tnuad risk and impact assessment actalia social sciences esci and numerical simulation itwm
danubius implementation phase project danubiusip

danubiusip is a 36month coordination and support action to support the ongoing development of danubiusri an environmental research infrastructure linking rivers and seas as it proceeds towards its operational phase the project proposes 7 work packages in two parallel workstreams that together will deliver a new governance structure for the ri as it transitions to danubiuseric enhance the ict potential of the ri to enable virtual delivery of key services implement the science and innovation agenda supported by agile and quality assured scientific services demonstrate the value of the ri through examples of the unique services that the ri can offer to endusers across europe and internationally expand the danubiusri community and enhance its standing in the wider european and international environmental ri landscape and ensure that the potential of danubiusri to have significant social and economic impact is widely communicated danubiusip is coordinated by geoecomar romania and brings together 25 experienced partners from 14 countries from across europe in a consortium with complimentary areas of multidisciplinary expertise across the freshwater and marine research fields the project specifically seeks to address recommendations from the recent esfri and highlevel expert group reports on danubiusri and make a significant contribution to the expected outcomes and wider impacts of the horizon europe programme as such the project considers the importance of sustainability of financial commitments the need to test the funding model and to enhance the visibility of the ri danubiusip will further demonstrate the efficacy of an integrated and interdisciplinary approach embracing a riversea continuum perspective to fill current gaps in the research and innovation landscape to address key societal challenges in these environments impacted by anthropogenic pressures and climate change
politics institutions and production networks

what are the political sources and consequences of economic globalization and how do political institutions shape globalization current frameworks for understanding the politics over economic globalization emphasize a fragmentation of politics political conflict breaks down to individual firms and citizens because the gains from trade are concentrated on large globally engaged and politically active firms departing from this view pinpoint develops an innovative framework built on the linkages between firms created by domestic production networks production ties imply a much broader impact of economic globalization because many domestic firms interact with international markets indirectly as suppliers and as customers of globally engaged firms moreover these linkages vary in quantity and quality to date we know surprisingly little about the role of production networks in politics which creates a mismatch between the structure of modern economies and current theoretical frameworks ignoring such ties risks misattributing the impact of economic globalization overlooking economic roots of political coalitions and misunderstanding the sources and consequences of economic globalization pinpoint places economic exchange between firms front and center in an account of the behavior of governments firms and citizens in the context of international markets and of the role of institutions in such an account pinpoint will provide theoretical and empirical innovations that lead to a revised understanding of the political underpinnings of economic globalization and of the mechanisms through which institutions shape economic globalization
delivering the next generation of open integrated assessment models for netzero sustainable development

recent literature has underlined the interplay among climate mitigation adaptation and finance as well as between climate action and other development agendas including sustainable resource use human development and equity and environmental pressures such an interconnected policy environment requires an integrated ecosystem of disciplines methods and tools despite the significant evolution of integrated assessment models iams in the last decade there remain several criticisms on their design use and adequacy to respond to unaddressed and emerging questions in the light of the paris agreement and netzero ambition these include openness legitimacy and ownership as well as technical feasibility to represent demandside and broader societal transformations crosssectoral interactions physical impacts and adaptation climate finance and labour dynamics and other sustainability goals diamond will update upgrade and fully open six iams that are emblematic in scientific and policy processes improving their sectoral and technological detail spatiotemporal resolution and geographic granularity it will further enhance modelling capacity to assess the feasibility and desirability of pariscompliant mitigation pathways their interplay with adaptation circular economy and other sdgs their distributional and equity effects and their resilience to extremes as well as robust risk management and investment strategies this will be done via integration of tools and insights from psychology finance research behavioural and labour economics operational research and physical science we will develop a transdisciplinary scientific approach to legitimise the implementation process and cocreate research questions that stretch the frontiers of climate science as well as establish vibrant communities of practice to transparently open model enhancements and to develop capacities thereby lowering the entrance barriers to the established iam community
corticostriatal circuit assembly in fragile x syndrome

fragile x syndrome fxs is the most common inherited form of intellectual disability and the main monogenetic cause of autism spectrum disorder fxs is caused by the epigenetic inactivation of the fmr1 gene during the first trimester of gestation fmr1 encodes for the fragile x mental retardation protein fmrp which regulates the transport and translation of mrnas involved in brain development already at 6 months of age fxs infants display structural alterations in several brain areas including the frontostriatal circuit suggesting an altered neural network assembly during fetal brain development structural anomalies in the frontostriatal circuit may underlie symptoms that strongly impair the life of fxs patients such as attention deficit hyperactivity stereotypic language and motor behavior and problems with impulse controlthis project aims at understanding the causal factors of the altered assembly of the frontostriatal circuit in fxs fetuses to achieve this goal we will generate human cortical and striatal brain organoids from fxs naive induced pluripotent stem cells and assemble these organoids into corticostriatal assembloids the resulting in vitro model will be used to conduct research in two directions first it will allow us to recapitulate corticostriatal circuit assembly in fxs identifying potential defects in axon growth and guidance neuron morphology and neural connections second we will investigate the molecular causes of these defects in particular how the absence of fmrp affects the expression of proteins involved in the assembly of the fxs corticostriatal circuit these studies will make it possible for the first time to spatiotemporally follow the pathological events that cause fxs both at the cellular and at the molecular level and they will pave the way for the identification of new therapeutic strategies to prevent the development of the disease
antiprotonic atom xray spectroscopy

numerous experimental observations have shown that the standard model is not complete precision measurements in quantum systems are one of the privileged frontiers for searching for new physics as new particles may couple to atoms provoking tiny changes in atomic structure that can be measured with stateoftheart methods such searches are founded on an accurate understanding of quantum electrodynamics qed the field theory that describes the interaction between light and charged particles while qed is well understood for light systems like the hydrogen atom where agreement between theory and experiment have been achieved up to thirdorder interactions with the quantum vacuum for highz atoms in the strong coulomb field regime the theory remains untested beyond firstorder interactions this is due to both experimental complications and theoretical uncertainties linked to unknown nuclear properties i propose a new approach for testing strongfield qed via the xray spectroscopy of antiprotonic atoms in these systems orders of magnitude higher coulomb fields can be obtained acting like a magnifying glass for qed effects that become easier to measure using transitions between rydberg states uncertainties from nuclear properties can be avoided and two orders of magnitude sensitivity can be gained with respect to the best current experiments making testing strongfield qed finally possible for a broad range of atomic speciesthe realization of this project relies on the novel combination of two new technologies slow antiproton beams at cern and quantum sensing xray detectors the compatibility of these two requires new developments that will lead to a dedicated precision xray spectroscopy platform for antiprotonic atoms with transverse applications beyond qed in nuclear and new physics searches
enhancing digital preservation strategies at european and national level

eosc eden will develop and establish a framework to identify what data are candidates to longterm preservation based on use benefit and quality and a model for reappraisal points along data lifecycle and test usability it will identify practices to support the creation of curation longterm preservation and access strategies in europe these outputs will be complemented by a set of usercentric tools services and standards that the project will develop to support the establishment of a european distributed infrastructure for longterm preservation curation and access in europe namely eosc eden will build a registry to mainstream tools and services from trustworthy repositories and longterm archives into eosc will enhance and develop new services to automate preservation and curation actions and will identify standards and protocols to submit and exchange candidate packages for longterm preservation the development of the services will be enabled via use cases and disciplineoriented pilots the disciplineoriented pilots developed by the early adopters of the project meaning the representatives of the seven different disciplines directly part of the project will test the eosc eden outputs from a disciplineperspective ad will be key to inform the creation of a supportkit to guide and support new users in adopting the results of eosc eden to ensure adoption and longterm sustainability of the results eosc eden will engage and collaborate with different types of stakeholders one key player for the success of the project will be the horizoninfra2024eosc0103 awarded project last but not least eosc eden will work to boost data curation and quality practices in europe by creating awareness of the benefits and by enhancing skills in the area in particular the project will establish an expert curation network with a representation on organisation repository generalistspecialist collectioncatalogue and at digital object type level
origin evolution and function of bacterial extracellular vesicles in the human hostgut microbiome system

bacterial extracellular vesicles bevs are small membrane vesicles secreted by a diverse range of bacteria that act as bioactive nanocarriers of a high diversity of proteins lipids and nucleic acids bevs have mostly been studied in pathogenic bacterial models owing to their causal role in pathogenicity compared to other microbial features such as taxa genes or metabolites bevs secreted by the large diversity of commensal bacterial species of the human gut microbiota have received little attention so far leaving their influence upon gut microbial ecology and human health almost entirely unknown we hypothesize that gut bevs and their molecular cargos ie the gut bacterial vesiculome play critical roles in bacteriabacteria and hostmicrobiome interactions and in shaping phenotypes of hostmicrobiome systems our project will enable a comprehensive profiling of bev molecular diversity across a large number of gut bacterial taxa and a functional analysis of their impact on interspecies and interkingdom interactions we intend to tackle these objectives through three aims 1 characterize the origin diversity and evolution of the human gut bacterial vesiculome 2 investigate the role of bevs in promoting horizontal gene transfers among bacterial species in the gut microbiome and 3 investigate the role of bevs on bacteriabacteria and hostbacteria interactions we will tackle each of these aims from three diversity perspectives investigating multiple bacterial species including geographicallydistinct healthy human populations and comparing healthy vs disease the project will expand our basic understanding of the evolution and function of bacterial vesiculation it will also generate the first atlas of bev profiles across gut bacterial taxa and host cohorts providing key resources to mine for vesicular characteristics and functions that have translational potential for biomedicine
crescine increasing the international competitiveness of the film industry in small european markets

crescines mission is to increase the competitiveness of the film industry across small countries in europe and improve the circulation of films and av content coming from small markets internationally crescines aims to enhance the competitiveness and the cultural diversity of the european film industry this will be achieved by understanding engaging with empowering and ultimately transform european small markets setting out from research and piloting in 7 markets in their smallness these markets underline the challenges and drivers one must consider to increase the competitiveness of the eu film industry as all crescine will address systematically the whole film production distribution and consumption ecosystem the aim is to innovate at all levels of the value chain from policies to ways of data management and analytics production business models and modes of distribution crescine will develop novel tools methods and strategic approaches that all build on the concept of smallness and the positive affordances it entails for the overall competitiveness of the european film industry crescine will address all expected outcomes of the call through the lens of exemplary european small film markets which stand for the majority of film markets in the european union crescine will establish an innovative model of analysis and evidence collection across the value chain that is framed by cutting edge data analytical models comparative benchmarks promulgated in light of best available evidence including unprecedented data sources the findings will lead to work on innovative solutions and testing of new tools policies business models or financing schemes and green strategies these activities feed the overall impact of the project and its ability to produce new tools recommendations guidelines and exploit results that nurture the transformation of the film industry in small european markets and beyond
xray fluorescence imaging of metal complexes in hypoxic tumor spheroids

according to estimates from the world health organization who in 2019 cancer is the second leading cause of death after heart failure before the age of 70 the field of metalbased anticancer drugs has been on the rise ever since the discovery of the anticancer properties of cisplatin in 1965 which is in daily clinical use against various types of cancer many compounds failed to enter clinical studies since their anti cancer activity is mainly studied in two dimensional 2d monolayer cells which does not mimic the complex tumor micro environment in humans in the human body the cancer tumors grow in 3dimensional structure hence it is vital to study the anticancer activity of a drug molecules in the 3d tumors rather in 2d mono layer cells next tumor hypoxia 1 oxygen a situation where tumor cells are deprived of oxygen is a major challenge for oncology in this project we propose the synthesis of nheterocyclic carbene18naphthalicanhydride conjugated series of metal complexes gold rhodium iridium to study the anticancer activity and penetration depths in 3d tumor spheroids under hypoxia we also investigate the activation by reduction mechanism in presence of cellular thiols and cytotoxicity in vitro 3d cell spheroids and compare the results among the three metal centers the metal protein interactions play key role in many biological processes hence we also investigate the metalprotein interaction studies using capillary electrophoresis inductivelycoupled mass spectrometry at secondment we will investigate the structure activity relationship between metals and of related coordinating ligands in 3d spheroid under hypoxic conditions we mainly utilize xray fluorescence xrf imaging and synchrotron radiation to test the cellular localizations and penetration depth for the proposed metal complexes this project is expected to yield unique insights towards optimization of nextgeneration antitumor drugs
the ideosphere of the late ottoman arabic press mapping the discursive field of authors and texts through computational approaches

sihafa explores the late ottoman 1890s1918 arabic ideosphere of the eastern mediterranean through its periodical press sihafa transcends the individual periodical for a systematic and computational study of the periodical press as a discursive field and at scale in order to better understand both the intellectual history of the eastern mediterranean at a crucial historical juncture and periodical production itself as msca fellow dr grallert will receive crucial training at universitt hamburg and will scrutinise a digital corpus of seven arabic journals from baghdad beirut cairo and damascus with more than 7 million words the result of his current research through a combination of stylometric authorship attribution social network analysis and close reading of biobibliographical dictionaries he will evaluate theoretical and methodological approaches workflows and tools developed in the global north for their applicability to cultural heritage of the global south a secondment at uniwersytet jagielloski will provide methodological training in stylometry the research objectives are to 1 fill a gap in research by developing and evaluating methods for the study of arabic periodicals
fitness for active distribution networks in smart grids

fitness is a doctoral network at the intersection of electric power distribution networks optimization electricity markets communications and control systems the project will develop new methodologies for active distribution networks services in the era of smart grids fitness is the first training network dedicated to this challenge and involves 4 beneficiaries and 6 associated partners from 7 eu countries guaranteeing a paneuropean approach in a multisectoral context universities research centres and smes fitness will train a new generation of scientific professionals who can transition between disciplines and between the public and private sectors based on i recruited researcher rr projects ii courses and workshops with the emphasis on handson collaborative learning and attention to transferable skills iii mobility knowledge transfer all within a training network that includes some of europes finest researchers
modelling plating morphology in lithiumion batteries for enhanced safety

eu will aim to have at least 30 million zeroemission vehicles by 2030 primarily powered by the current energy storage technology of choice lithiumion batteries despite remarkable achievements in developing control strategies over recent decades many fundamental scientic issues underpinning the safety of these batteries remain elusive due to a lack of controloriented models for predicting the internal phenomena that can trigger internal short circuits and the consequent thermal runaway in this proposal we document a wholistic new physicsbased modelling approach which adequately incorporates a highly accurate description of battery electrochemistry as well as the accompanying subtle lithium plating phenomenon it will allow reliable prediction of the occurrence of safety accidents subject to battery operational conditions and the seamless integration into a safetyguaranteed battery management system as an mscapf fellow dr yicun huang will receive crucial training at the chalmers university of technology and engage in detailed battery modelling works which span the areas of computational materials and electrical engineering the interplay between the two areas will spark an innovative and productive throughput including 1 a multiphase electrochemical model under normal battery operations 2 a highfidelity materials model for the growth morphology of lithium plating and 3 controloriented models for battery safety assessment the result of this project will include a groundbreaking multiplemodel framework enabling fast and accurate battery safety state prediction and analysis a new interdisciplinary research product amalgamating materials modelling and control algorithms outreach and dissemination to crucial target audiences and a solid foundation for a safetyguaranteed battery management system intended to revolutionise electric vehicles