Dragon09/odtu_chatbot huggingface dataset:
innovating new space frontiers harmonised federated and fractionated systems unlocking fresh perspectives for satellite services

major developments in small satellite technologies coupled with the rapid commercialisation of new space are disrupting the space landscape a driving role rests with the telecommunication vertical where market demands for global connectivity led to the emergence of leo and meo megaconstellation and are accelerating efforts for the integration of nonterrestrial with terrestrial networks core to this vision is an architectural paradigm shift from large monolithic satellites to an orchestrated network of multiorbit spaceborne nodes of various sizes and capabilities on the other hand space missions traditionally dominated by governmental initiatives such as navigation gnss and earth observation eo are slower in adopting the new space spirit towards coordination and synergetic exploitation of emerging and established satellite systems yet these systems have had transformative impact on our daily lives along a plethora of applications and verticals anticipating the next new space frontiers in commercially driven missions within these domains a central view of harmony is that step change potential will be released by adopting distributed satellite architectures across a range of existing and new applications where the space environment provides unique benefits placing innovative space services at its core harmony will adopt a crossdisciplinary vertically integrated approach in the study of federated and fractionated satellite system architectures and the development of core underpinning technologies in a doctoral network that will nurture future european new space leaders
seminal sufism in motion the oldest extant arabic encyclopedia of islamic mysticism and its dissemination

semensuf is an interdisciplinary and collaborative project at the crossroads of philology intellectual history and material culture that adopts basic tools of digital humanities for arabic literary and religious studies it aims at providing an openaccess scholarly edition and lucid knowledgesharing english annotated translation of the oldest extant encyclopaedia of islamic mysticism the book of flashes in sufism by ab nasr alsarrj d 988 through its innovative method semensuf aims at laying the foundations for a new historical and textual approach to the editing of early sufi sources the philological atomization of the work in textual units the study of the manuscript transmission and material culture and the digitization of later related sources are critical for shedding light on channels of knowledge transmission centers of learning and scholarly networks in early sufism and more broadly in islamic culturesemensuf strongly believes that editing and translating a 1000yearold work of mysticism can have a major impact on european multicultural and multifaith societies in fact the book of flashes tackles several intra and extra islamic issues that are still very much relevant to todays europe it highlights how mysticism is and should be considered a genuinely component of islam invalidating most contemporary neosalafi claims to the contrary more importantly the book of flashes reflects a strong concern for and appraisal of heterogeneity and pluralism within islam it is a hymn to diversity and to coexistence of different practices and sensibilities which collaborate rather than compete resulting in a shared spirituality semensuf thus aims at having an impact on european pluralistic society by making available to a wide audience a universal text which will stimulate a reflection on mysticism as a safe space for intercultural and interfaith pluralism dialogue and inclusivity
recycling plastic waste into highvalue materials closing the loop

globally 359 million metric tons of plastic were produced in 2018 and europe produced 17 of this amount in the same year 291mio tons of plastic waste was generated in the eu and only a third was recycled while sorted and pure plastic waste can be recycled relatively well a major problem is recycling of unsorted waste which still holds a large share of valuable carbon feedstock but is currently either landfilled or energetically valorised ie incinerated both producing greenhouse gases ghg emissions instead of recovering the precious carbon feedstock contained hence there is an urgent need to develop new technologies that can not only valorise unsorted plastic but also other waste in large amounts to yield material streams that can replace fossil material streams one promising technology to recycle unsorted heterogeneous plastic waste is pyrolysis while the low to medium temperature pyrolysis 400c produces mainly liquid oil that needs to be fed into the furnace of the steam cracker unit at higher temperature than 900c to produce olefins with our proposal at hightemperature pyrolysis 850c syngas stream light olefins rich is fostered and could be integrated downstream the furnace of the steam cracker however the use of hightemperature pyrolysis for plastic waste recycling has not yet become an industrial practice since gas treatment and integration present a great challenge plastics2olefins project will address this challenge it will design build and run a demonstration plant for recycling of unsorted plastic waste at repsols plant puertollano spain which will be digitalised and run on 100 renewable electric energythe project estimates to reduce the lifecycle ghg emissions by 7080 compared to incineration and existing plastics recycling processes providing an important contribution to the eu reaching climate neutral by 2050 and set a pathway for commercialisation of renewable plastic feedstock replacing fossil fuels
human blastoids a drug discovery platform for womens reproductive health

the first weeks of human pregnancy are crucial as early abnormalities or insults result in infertility therapeutics acting at the onset of embryonic development would offer huge opportunities to improve public health through effective family planning and to reduce an ongoing global fertility decrease with profound economic social environmental and geopolitical consequences unfortunately a drug development program on human embryos is unfeasible due to the inaccessibility and scarcity of embryos and to ethical issues associated with them as a result the attrition rate of drugs for reproductive health is high for all major in vitro fertilization ivf and pharmaceutical companiesrecently an alternative approach arose from stem cells selforganizing into structures closely resembling preimplantation embryos blastocysts which we termed blastoids because stem cells can be largely multiplied this embryo model provides a scalable and ethical alternative amenable to drug screens thus opening numerous possibilities for therapeutic breakthroughs here i propose to use human blastoids to discover molecules for womens reproductive healthblastoids offer a unique opportunity to establish a drug discovery program for early pregnancy and an alternative to the use of animal and human embryos as such this path has the potential to decrease the cost of drug development and to increase the rate of approved drugs for reproductive health the aim of blastoiddiscovery is to investigate the commercial feasibility of using blastoids as a new and highly costeffective tool in the discovery of therapeutics for reproductive health
fimuskraft biogas plant fkbp a revolutionary and costeffective biotechnological method to treat and valorise biowaste

anaerobic digestion ad for the treatment of organic wastes has been hailed as a green and sustainable technology however ad adoption is still hindered by various limitations eg ad plants are applied for centralised waste management with production of pathogenic and low quality digestates usually landfilled leading to no waste valorisation ad plants produce biogas of low yield and energetic potential in addition they are significant capital investments with a long payback to solve these pains fimuskraft have developed the fkbp a system which elegantly combines a biogas fermentation with an b innovative biowaste enzymatic prehandling process and c microturbine with gas analysis and control system the fkbp is compact and modular and able to simultaneously treat various types of biowaste to produce electricity heat and high quality ecological organic fertilizer the fkbp is the first biogas plant able to produce higher energetic biogas up to 97 ch4h2 mix
ai guidance for robotassisted eye surgery

retina indications are the leading cause of visual impairment in industrialized countries and posing a big unmet socioeconomic challenge performing surgical actions directly at the retina one of the most delicate and sensitive areas of the human body with ultrathin microsurgical instruments and with a limited view makes retina surgery a very challenging discipline with surgeons working at the limit of what is possible requiring years of training and experience to reach proficiencythe geyedance project is directly addressing this need by translating methods from artificial intelligence to the area of surgical robotics together to be used for an advanced user support for reducing the mental and physical load of the surgeon work in the project is building on two existing main blocks the ce certified robot platform pss from project partner preceyes and a prototype for a commonpath oct system with extended measurement depth from partner acmit for the aicomponents to be developed two european leading groups in this domain altairuniversity of verona and artorguniversity of bern are part of the consortium seamless involvement of key stakeholders during the complete development phase is indispensable for a meaningful outcome and thus a prominent board of worldwide leading eye surgeons led by partner university of ferrara will provide user insight and evaluate the resulting advanced robotic solution development and validation of the geyedance system is strongly supported by industrial partners carl zeiss ag and carl zeiss meditec aginline with the concept of the innovation actions instrument the project aims to generate tangible and closetocertification technology reaching a trl of 7 or even higher being evaluated in the framework of a first clinical trial all together the planned aibased guidance system geyedance will help the consortium to further consolidate their leading position worldwide will help retinal surgeons to optimize their task and finally will help the patient by contributing to a better surgical outcome
green deal inspired correlative imagingbased characterization for safety profiling of 2d materials

accords will develop an imagingbased characterization framework accords framework for the holistic correlative assessment of graphene family materials gfms as a representative of 2d nanomaterials nms to assess and predict 2d nms health and environmental risks the accords framework will operationalise safe and sustainable by design ssbd strategies proposed in past or ongoing h2020 projects or within oecd by correlating low medium and highresolution physicochemicalbiological imagingbased methods with nonimaging methods in a tiered approach accords will deliver the accords framework and user guidance new imagingbased characterisation methods 36 methods reference in vitro tests up to three new tests new reference 2d nms up to three for different matrices a new minimum information reporting guideline for fair data sharing and reuse of images as well as an atlas with reference images for diagnostics of compromised safety of gfms gfm products the new guidelines and standard proposals will be submitted to standardisation bodies to allow creation of regulatory ready products the novelty of accords is in translating the principles of medical imagingbased diagnostics to 2d material hazard diagnostics accords will accelerate industrial sectors in the area of aviation marine construction drone production flexible electronics photovoltaics photocatalytics and print inksbased sensors the value accords proposes to the graphene industry are practical easy imagingbased tools for gfm quality monitoring next to the production line with a possibility to be correlated with advanced highresolution imaging characterization methods in case hazard ie deviation from controls benchmark values are diagnosed the accords framework and tools will contribute to the european green deal by addressing the topic graphene europe in the lead and to a new european strategy on standardization released on 2nd february 2022
traitorvirusguided discovery of antiviral factors

viruses may seem smart since they rapidly develop new skills to spread in humans however they are actually just masters of trial and error their short generation time enormous reproduction and high variability allows viruses to try countless variations a few of these will enhance viral spread and in the worst case enable viral pandemics it is conceivable that viruses evolve to counteract those defence mechanisms that would otherwise be most effective against them usually it is hard to assess why specific changes are advantageous this is especially true for adaptations enabling viral pathogens to counteract innate antiviral factors because these cellular proteins and their viral antagonists are numerous and highly versatile here i propose to combine the advantages of the revolutionary crisprcas9 technology with the enormous adaptive power of viruses to develop a novel approach allowing robust specific and genomewide unmasking of antiviral mechanisms in principle we will equip hiv1 with genetic scissors to convert them into traitor viruses revealing their cellular opponents to achieve this we will generate libraries of replicationcompetent hiv1 constructs expressing guide rnas as genetic tools with the potential to inactivate every human gene in cas9 expressing cells virus variants expressing guide rnas eliminating antiviral genes will be selected by in vitro passaging and identified by next generation sequencing utilization of different viral backbones will allow the discovery of key defence factors against viral zoonoses and spread in humans finally we will determine the antiviral spectrum and inducibility of innate antiviral factors to identify vulnerabilities of viral pathogens that can be exploited in preventive and therapeutic approaches the project will establish and apply an innovative highly versatile approach to uncover our antiviral defence mechanisms with the ultimate goal is to achieve better control of viral pathogens
high efficiency bifacial thin film chalcogenide solar cells

cigs solar cells currently reach 23 efficiency with a metallic back contact and a 2m thick absorber layer as well as excellent stability hibits partners will introduce a disruptive device structure that allows a high degree of bifaciality and photon recycling the efficiency will be improved beyond 25 by the innovative high quality cigs absorbers and passivation at the back contact which allows to remove compositional gradients and reduce absorber thickness hibits will explore four different applications that all use these features including bifaciality flexible and reflective semitransparency and suitability for tandems while the bifaciality will harvest stray light reflected from the ground and thereby increase the yearly yield the reflective and flexible will enable photon recycling for lightweight modules the necessary back reflector is easily integrated into the bifacial hibits cells to close the gap in efficiency between large area modules and record cells hibits will improve monolithic integration to increase the productive area of the module and the semiconductor quality by fastfeedback methods fit for industrial processes the applications foreseen as results from hibits respond to market demands and are particularly well suited for building or vehicle integration or agriphotovoltaics modules for these new applications will be outdoor tested in three different european climates demonstrating higher energy yield and stability life cycle analysis and costing taking aspects of circularity into account will underline the superior sustainability of these new modules hibits includes 5 european pv manufacturers will improve a technology that does not depend on imports of ingots or wafers reinforcing the european pv value chain the results will boost thinfilm manufacturing by higher efficiency lower raw material consumption shorter and wellcontrolled processes better module technologies and novel applications
enhancing soil health through valuesbased business models

land managers combine manmade resources with natural resources to produce marketable products like food feed fiber and wood but at the same time produce ecosystem services that are generally not marketed or compensated however land managers generally have little incentive to invest in healthy soils as they cannot sufficiently capture the value generated by these ecosystem services soilvalues aims to contribute to the conditions for developing successful soil health business models these are models in which land managers make production decisions that result in higher levels of soilbased ecosystem services ses and in which they are paid for the nonmarketed services they generate in order for such business models to function three important conditions need to be fulfilled 1 the outcomes of ses need to be measured thus requiring knowledge indicators and models 2 the data and information generated by these indicators and models need to be exchanged to facilitate monitoring reporting and verification mrv and 3 all these activities should be governed by an appropriate institutional framework consisting of the necessary legislation standards and incentive schemes to enhance the conditions for developing successful soil health business models soilvalues will 1 provide a comprehensive assessment framework addressing all factors influencing the development of business models for investing in soil health 2 establish 6 testing grounds across europe to test and improve emerging and designing new soil health business models 3 establish 12 communities of practice of land managers value chain actors investors and public authorities for soil health business models 4 design a comprehensive toolbox of incentives and policy recommendations to facilitate soil health business models and 5 raise awareness and exchange knowledge for soil health business models
support to set plan implementation working group and european technology and innovation platform for ocean energy

seetip oceans mission is to enhance cooperation and collaboration amongst stakeholders both inside and outside of the european ocean energy sector this mission is broken down into 6 objectives1maximise european scientific excellence in ocean energy2make sustainability and the just transition an integral part of ocean energys development3build a deeper understanding of how ocean energy can optimally fit into the wider energy industrial infrastructure systems and planning systems and help realise this integration4empower the set plan ocean energy implementation working group and other public authorities by monitoring analysing and reporting annual commentary on the sectors progress5reinforce and expand the ocean energy network through strong outreach actions6continue the work of etip ocean and set plan ocean energy iwg after the project endsocean energy can power european society and economic life with electricity that is renewable dependable and in harmony with local communities and environments to reach this potential sectoral stakeholders must collaborate share knowledge and avoid duplication of efforts seetip ocean will do this by supporting the activities of both the european technology innovation platform for ocean energy etip ocean and the set plan ocean energy implementation working groupthe projects objectives will be achieved through coordination actions bringing individuals and organisations together to exchange knowledge create new knowledge and build more and deeper connections widespread knowledgesharing will be facilitated via webinars and workshops based on these exchanges seetip ocean will publish accessible studies and reports that will be widely disseminated across and beyond the ocean energy sectorthe set plan ocean energy iwgs work will be supported with annual updated information on sectors progress and policy and funding support uptodate and accurate data will inform the iwgs decisionmaking
one health approach to understand predict and prevent viral emergencies from bats

in recent years several novel rna viruses found in bats have been associated to the emergence of human diseases surveillance in this extremely diverse group of mammals has revealed that bats are significant reservoir hosts for many viruses whose zoonotic potential deserves further insights onebat aims at investigating the trigger for viral spillover from european bats to humans or domestic animals using a multidisciplinary consortium of ecologists virologists and modellers in response to the outcomes foreseen by the call onebat will unravel the complex interplay between natural and spillover host pathogen and environment that determines the emergence of infectious diseases information on viral replication pathways antigenic markers and in vitro and in vivo screening of antivirals will advance the availability of current and future therapeutic and prophylactic tools for disease xdue to technical and logistical reasons onebat will not investigate all the bat species and pathogens circulating in europe it will rather provide wellbased evidence on relevant model species that could be used to study other bat species or viruses that already are or may become of interest over the lifetime of the project or in the future we will focus on the miniopterus schreibersii bats a species in significant decline across europe and on filoviruses coronaviruses and lyssaviruses as highconsequence pathogens known to circulate in the target bat in addition to the specific information stemming from the project onebat will establish a methodological platform that will make available the developed ecological and virological tools among them innovative protocols for serological and virological investigations of these smallseize animals harmonised longitudinal surveys across europe including tracking systems ultimately onebat will equip southern and eastern eu countries with 20 vhf receivers that could be used for further studies on all flying animals