Dragon09/odtu_chatbot huggingface dataset:
remoteworking multiple impacts in the age of disruptions socioeconomic transformations territorial rethinking and policy actions

today rw is mostly conceived as an arrangement enabling flexible work organization however remaking contends that rw can be more than that if the multiple effects induced by rw on individuals business models and the socioeconomic sphere are properly understood and addressed by policymakers it might become a lever contributing to shaping ongoing social economic and spatial structural changes at the basis of remaking there is a profound consideration of the ongoing megatrends ie digital transformation flexibilization of production models that have initiated rw and of the recent shocks ie the pandemic and russias war in ukraine that have consolidated the diffusion of different forms of rw through this angle the multiple effects induced by rw call for rigorous analyses to support decisionmakers in balancing opportunities and problems linked to rw for a potential rethinking of territories namely in rural areas remaking aims at delivering a policyoriented framework reflecting the new and multifaceted realities of rw facilitating policymakers to adopt placebased policies balancing the opportunities and risks of rw and sharing practices to foster mutual learning on rw in the novel scenario of megatrends and shocks these objectives will be achieved through participatory research activities across 4 case studies each addressing a different form of rw digital nomadism postpandemic highskilled in hitech sectors and enforced remote workers the 4 case studies encompass overall 7 countriesitaly greece portugal germany czech republic ukraine ireland for each country 1 secondtier city and 1 rural area will be studied remaking generates an impact on sociospatial transformation processes across secondtier cities and rural areas in terms of improved planning design and implementation of multilevel policy promotion of territorial socioeconomic resilience and development and advanced understanding of rw multiple impacts
safe and sustainable by design integrated approaches for impact assessment of advanced materials

sunrise will develop an overarching integrated impact assessment framework iiaf designed to support ssbd decision makingalong lifecycle stages and value chains of advanced materials adma and their products the iiaf will be a 3tiered approach witheach tier corresponding to an integrated methodology for health environmental social and economic impact assessment supportedby a toolbox targeting a different group of users at different stages of the innovation process and requiring a different level of dataand expertise to enable these methodologies to account for stakeholder tradeoffs in decision making we will develop them in a cocreative process that balances the perspectives and interests of key actors from industry including smes regulation policy consultancy academia and the civil society to facilitate costefficient generation of input data for the iiaf we will develop and apply integrated approaches to testing and assessment iata new approach methodologies nams as well as screening level and more advanced sustainability assessment tools based on environmental and social lifecycle assessment lifecycle costing and circularity analysis the iiaf its integrated impact assessment methodologies and the toolbox of newly proposed methods and tools will be provided as an open fair web platform including a database designed to support impactsbased decision making for future adma these outcomes will be tested and demonstrated in industrially relevant case studies the goal is to foster acceptance and support for the iiaf platform and the newly developed approaches to ensure their adoption and implementation by the stakeholders the new knowledge generated in the project will be transferred to public authorities at the eu and national levels to support them in the implementation of ssbdrelated policies for chemicals and materials based on improved understanding of potential safety and sustainability tradeoffs
design for igatype discretization workflows

after more than a decade of research isogeometric approaches are starting to make inroads into commercial solvers and thus starting to be relevant in the industrial practice outstanding challenges still exist in the use of the underlying cad technologies and in particular in the use of trimmingthe main objective of the gecko project is to help solving the outstanding difficulties by improving the current state of the art and by integrating academic research within the industrial workflow this will be achieved by ensuring that opensource solvers developed in the academia for both solid and fluid dynamics are able to use as an input domain any cad geometry even in cases in which the geometrical definition is not optimal ie poorly defined or dirty geometries in this regard an efficient and robust solver design must be implemented to be capable of performing seamless designthroughanalysis workflows the goal will inherently imply collaborating with the prepost processing industry represented in the proposal by the company betacae with solver vendors dynamore and end users idiada to ensure that a smooth path is defined to allow such convergence the overall project outcome will be to form a new cohort of experts on the topic and to enhance the open source tools and operational workflow so that they can effectively complement commercial based approaches this in turn will allow addressing relevant bottlenecks as identified by the industrial partners so that the solution can be eventually backported into commercial solutions another important objective in the gecko project is to empower and generalize the currently available solutions when dealing with complex nonlinear models solvers in computational fluid dynamics cfd computational solid mechanics csm acoustics vibroacoustics reduced order models rom and surface mapping
recovering plasmafacing components temperatures in fusion devices from ir camera measurements

infrared ir cameras are key diagnostics to monitor and control plasmafacing components pfcs in fusion devices nevertheless the use of allmetallic pfcs with low and variable emissivity 0105 makes it difficult to obtain a correct surface temperature measurement the radiance collected by the ir camera includes both the thermal radiation emitted by the target and parasitic radiation coming from the targets surroundings furthermore target emissivity changes with the surface temperature and roughness this causes significant errors in the surface temperature measurement that we need to address for achieving high power and safe plasma operation inaccurate interpretation of ir temperature measurement could endanger machine safety temperature underestimation or on the contrary lead to unnecessary pulse interruptions that reduce the overall performance of the machine temperature overestimation the current approach is to convert the radiance collected by each pixel in an apparent using a physical relationship between emitted radiance and temperature plancks law because a portion of the collected radiance is due to reflection on the target a systematic error is made this method is unable to recover the portion of reflected radiance and to deduce the correct temperature of the target using only the emitted radiance the proposed technique in this project is to use a digital twin of the machine and to make in it assumptions on the temperatures of the different elements of the machine in order to simulate the images that would be measured under these supposed conditions by comparing to the real image measured by the camera and using optimization techniques the assumptions on the parameters can be updated until the simulated and measured images are close enough it is then deduced that the assumptions made on the parameters of the digital twin are correct and that they correspond to the real temperatures in the machine
sic composite claddings lwr performance optimization for nominal and accident conditions

the fukushima daiichi event in 2011 demonstrated the need for enhanced nuclear energy safety becoming a major driving force for global investments in accidenttolerant fuels atfs over the past decade candidate atf cladding material concepts that are being developed in replacement of the standard zirconiumbased alloy zircaloy fuel cladding materials used in light water reactors lwrs must outperform commercial zircaloys under nominal operation hightemperature transient 1200c and accident 1200c conditions sicsic composites are a rather revolutionary atf cladding material concept exhibiting inherent refractoriness pseudoductility and a lack of accelerated oxidation during a lossofcoolant scenario due to their unique potential in meeting the stringent property requirements of the atf cladding application sicsic composites have already claimed large global investments despite these investments all stateoftheart variants of the sicsic composite cladding material concept must still overcome inherent shortcomings prior to their perspective deployment two important weaknesses are their inadequate compatibility with the coolant water and steam and the early 2 dpa saturation of radiationinduced swelling during nominal operation scorpion strives for a radical improvement in the performance of sicsic composite fuel claddings by highly innovative material tailoring on the nanoscale so as to limit hydrothermal corrosion and radiation swelling while also modifying the fibrematrix interface for better stability under irradiation and in hightemperature oxidizing environments scorpion is an atf applicationdriven international collaboration between europe the usa and japan which combines multidisciplinary scientific excellence stakeholder knowhow and cuttingedge manufacturing approaches to produce proofofconcept sicsic composite cladding materials with a radically optimized performance for geniiiii lwr service environments
v2x cell free massive mimo networks with active ris from analytical optimization to federated machine learning

the reconfigurable intelligent surfaces ris cellfree cf massive multipleinput multipleoutput mmimo and vehicletoeverything v2x are key technologies for nextgeneration wireless communication ie beyond 5g and 6g the cf mmimo involves deploying many aps in a large geographical area to jointly serve all users v2x allows vehicle user equipment vues to communicate with base stations pedestrians and other vehicles the high mobility of vues leads to frequent handovers and channel ageing this makes the cf mmimo ideal for v2x since handovers are eliminated to reduce the impact of channel ageing more aps must be deployed which increases the power consumption the ris comprises many passive reflecting elements res which can independently induce phase and amplitude change with marginal power needs thus the ris can improve the spectralenergy efficiency seee however the passive ris suffers from doublefading attenuation which may be detrimental for vues this proposal seeks to analyze the seee of the active ris arisaided cf mmimo enabled for v2x each ap serves vues with the aid of multiple ariss we will derive closedform solutions for the uplinkdownlink se by assuming imperfect channel state information spatially correlated rician channels and channel ageing for the aris while increasing the reflected signal amplitude improves the desired signal it also enhances the noise also the aris requires extra power to amplify the signal which grows the network power consumption the tradeoff between the se and ee will be analyzed to identify the best operating regions increasing the aps or vues transmit power may increase the se but saturates at a point due to interference therefore we seek to jointly optimize the power aris amplitude and phase with the objectives of 1 maximizing the sum se 2 maximizing the ee finally we propose a federated learning algorithm for csi forecasting to mitigate channel ageing effects
preclinical development of a 3rdgeneration interleukin2 targeted to inflammatory sites

as major players in the regulation of immune responses regulatory t cells tregs are important therapeutic targets for autoimmune and inflammatory diseases interleukin2 il2 used at low doses il2ld stimulate and expand tregs in vivo while 1stgeneration native il2ld are currently under extensive clinical evaluation pharmaceutical companies are developing 2ndgeneration il2 muteins with improved halflife and activitywe aim to develop 3rdgeneration il2 specifically targeting inflammatory sites il2it by using antibodies abs against oxidation specific epitopes ose that are both universal markers and mediators of inflammation il2oseab fusion proteins should allow dampening of local inflammation by a doublehit mechanism involving ab neutralization of proinflammatory ose and il2 stimulation of tregsas a proof of concept we designed a first il2it in which an il2n88r mutein is fused to an scfv from a prototypic antiose ab this il2it i binds to il2 receptors and ose ii has an extended halflife and iii superior therapeutic efficacy compared to native il2 in miceour general objectives are to design an optimized il2it by testing combinations of different antiose ab with il2 and il2 muteins and to complete its preclinical development in mice and macaques we will validate the use of il2it in cardiovascular diseases cvd ie atherosclerosis vasculitis myocardial infarction and sleassociated cvd as these conditions have been shown to be improved by treg infusions native il2 and oseabs in mice carried by leading experts in the use il2 oseabs models of cvd and clinical trials with native il2 the successful validation of an il2it will open a new era for highly selective and effective immunotherapies based on treg stimulation for diseases that represent a leading cause of death and morbidity furthermore it will validate the broader concept of targeting any therapeutic molecule to inflammatory sites
enhancing bioavailability of beneficial polyphenolic compounds in food via advanced materials engineering

a diet rich in plantbased foods abundant in beneficial polyphenolic compounds pcs is pivotal in preventing civilizationrelated diseases pcs are valued for their robust antioxidant properties and prebiotic potential however their inherent instability and sensitivity to environmental factors and processing methods pose challenges rapid oxidation and limited bioavailability in the human body underscore the need for effective stability enhancers and delivery systems in principle the encapsulation technique provides prolonged and controlled release of food ingredients and increases the stability and bioavailability of bioactive compounds the complexity of the capsule design however has consumed considerable resources in the food science field but has yet to result in satisfactory results in terms of pcs deliverythis project offers a fresh perspective by treating capsule design as a materials engineering task we aim to leverage cuttingedge material design preparation and characterization techniques to enhance the bioavailability of encapsulated pcs our approach will involve layerbylayer methods to create model systems with precise control over the morphology of polysaccharide and protein encapsulation layers cofocal microscopy sem imaging and nanomechanics will provide insights into structure stability and pc release in vitro to optimize layer composition efficiently we will integrate robotaided experimentation and machine learningthese efforts will culminate in developing a material acceleration platform a versatile methodology for designing polyphenolic compound delivery systems for food applicationsto achieve these objectives the researcher will be provided trainingthroughresearch in a broad spectrum of preparation and characterization techniques aimed at layerbylayer systems and datadriven experimentation approaches such as the design of experiments and bayesian optimization
the structure of normativity

some of the core fields of philosophy including moral philosophy value theory and epistemology are at their heart concerned with normative questions questions about what is good or bad right or wrong justified or unjustified these questions concern the content of judgements that human beings are constantly making and that structure our way of thinking feeling and acting but while there is wide agreement in contemporary philosophy that normative judgements form a unified and important category of human thought philosophers still struggle to understand what normativity actually isone highly attractive hypothesis is that normativity can be analysed in terms of reasons ie in terms of the factors that count in favour of or against actions or attitudes but the systematic exploration of this reasonsfirst approach is still lacking reasons f1rst aims to undertake this muchneeded investigation fostering multidisciplinary conversations the project will explore the reasonsfirst approach on a large scale it seeks to address recent challenges to the reasonsfirst approach and to show that it prevails over alternative approaches to understanding normativity reasons f1rst thus pursues a twofold objective i to assess the merits and demerits of the reasonsfirst approach compared to alternative proposals and ii to work out in detail how different normative phenomena including values obligations and rights the justification of beliefs as well as appropriateness norms for emotions can be explained in terms of reasons building on the work of a multidisciplinary research team reasons f1rst aims at nothing less than a fundamental understanding of one of the most important concepts of contemporary philosophy
one health sustainability partnership between euafrica for food security

nestler is a joint project between the eu and african member states designed to promote onehealth sustainable partnership the project aims to bring together interdisciplinary technological advances to effectively monitor the wellbeing of animals plants and humans in a holistic approach the complementarity between the stakeholders will extend upon the ongoing initiatives from farm2fork strategies that have resulted in integrated software systems and solutions the novelty of the nestler project lies in the development and integration of advanced remote sensing technologies the project platform will develop software interfaces for ingesting satellite data sources along with video streams captured from unmanned aerial vehicles and other iot devices installed for monitoring the environmental and animal wellbeing the largevolume of data ingested into the platform will be subjected to additional processing for the extraction of intuitive insights with the assistance of machine learning algorithms and deeplearning network architectures the extracted insights will be translated into predictive models affecting onehealth sustainability programme using the machine automation additionally the nestler project will also undertake research activities to investigate the impact of insect protein on the circular economy for the wellbeing of animals the project will develop methodologies for edible insect farming which will be in animal farming the project will also conduct research studies on the impact of animal waste in cropbased farming in complementary to the analysis of health benefits the project will also undertake efforts to evaluate the economic sustainability of such farming practices which will lead to the setup to joint euafrica joint task force on onehealth sustainability the outcome of the project will result in a transition from a linear economy to a circular economy delivering sustained growth and development
wind turbine blades end of life through open hubs for circular materials in sustainable business models

a sustainable circular economy in the wind sector requires to solve the end of life problematic of the wind turbine blades prioritizing environmental factors and fairly sharing the efforts to overcome the technologic economic and social barriers among all the key actors to this end eolohubs will develop 3 open hubs to codesign cocreate and demonstrate new technologies organizational structures business models and legal recommendations to implement ce according to the needs of the different european regions the knowledge hub will connect stakeholders to effectively collaborate on similar initiatives sharing data and spilling over good practices to replicate success stories during and after the project the other 2 hubs will build a largescale demonstration covering the full value chain for wtb reusing and recycling from the dismantling to the valorisation in heavy composite sectors through efficient waste recycling solutions while specific needs of eol composites in wind technology are representing the onshore hub will include the necessity of implementing a zeropollution and mobile system for dismantling onshore technologies without jeopardise the environment and maximising the recovering of paints and coatings as well as enabling the recyclability of chemical building blocks solvolysis the multisectorial and offshore hub will include the necessity of adapting current high volume composite recycling technologies pyrolysis to obtain a high yield of rgf and cgf in a zerowaste approach collaborating with other sectors as well as to demonstrate how to prepare the gateways for offshore technologies to connect to the new value chain for recycling wtb in this way eolohubs will create a longterm collaboration of key actors with access to relevant demonstration scenarios to ensure the recycling of almost 90 of the wtb materials creating a circular economy that generates jobs and reduce greenhouse gas emission by 2030
malaysian reclaimed landscapes urbanization heritage and sustainability along the littoral

mareland is an interdisciplinary project and ethnographic study of land reclamation along the malaysian littoral reclamation is the act of creating new land and artificial islands from the sea the approach that the state and developers are taking is reminiscent of neocolonial and neoliberal conceptions of the mare nullius nobodys sea an empty space to be transformed by largescale construction projects many are concerned about the socioecological effects for the environment and coastal communities on the one hand reclaimed landscapes are being planned for the development of hightech fantasies of a luxurious lifestyle in a greener and smarter environment on the other hand such projects are intended to transform spaces that nevertheless represent enduring heritage such as fisheries seascapes and biodiversity reclaimed landscapes thus emerge as contested spaces where what is not considered heritage becomes attractive for development mareland explores the competing discourses of sustainability and cultural heritage held by a variety of actors situated at the intersection of urban anthropology and critical heritage studies the project will examine two underresearched themes a environmental activism and the critique of heritage hierarchies and b the study of urbanization at sea through ethnographic research in two field sites interviews and the organization of codesign activities with local stakeholders the project seeks 1 to advance empirical knowledge on practices related to the right to the cityright to the sea and the ways environmental activism and discourses on sustainability and heritage conservation unfold on the ground 2 to advance theoretical knowledge on the masterplans and compensation policies at work around yettobebuiltislands and 3 to develop a toolkit that disseminates solutions to conflicts over land reclamation by using ethnographic evidence to reshape policyoriented practices in land reclamation