Dragon09/odtu_chatbot huggingface dataset:
innovative education for the bioeconomy

biobeo is a 2 year 2m project with 15 partners bridging theory and practice its overall aim is to develop and deploy an education programme to enhance understanding and engagement across society regarding lifestyle circularity and bioeconomy using 5 bioeconomy themes interconnectedness outdoor learning forestry life below water and the food loop a network committed to promoting the bioeconomy concept will cocreate and codeliver the programme biobeo will provide for better coordination between bioscience and education in schools by developing the circular economy sciencesociety message with a particular focus on circular lifestylebehaviours and a governance framework on societywide engagement in bioeconomy policy biobeo will address social issues such as gender bias disadvantaged youth groups migrants and members of society with additional needs we shall 1 increase awareness of environmental social and economic benefits of sustainable and circular bioeconomy among young people at preschool primary and secondary school level 2 identify institutional and cultural barriers 3 develop innovative approaches and digital toolkits for educational and information materials 4 pilot biobeo education programme reaching 35 schools 1000 university students 1800 parentsguardians and 100 teachers across ireland belgium netherlands and germany 5 demonstrate a measured increase in engagement of young people and their intention to pursue education and careers in life science technology and bioeconomy 6 enhance governance of bioeconomy related processes within society by engaging european citizens from young to old in active policy making 7 coordinate communication and dissemination to optimise the reach and visibility to students teachers policy makers and parents biobeo will contribute to the transition to a sustainable eu circular bioeconomy by enhancing societywide awareness and inspiring europes youth to pursue stem related careers
costeffective sustainable and responsible extraction routes for recovering distinct critical metals and industrial minerals as byproducts from key european hardrock lithium projects

europe is 100 reliant on imports of li for the liion batteries that are central to decarbonising the energy and mobility sectors some fraction of our needs can come from recycling the batteries already in use but realistically primary supply will still have to cover 90 of the li requirement paradoxically europe hosts 27 li hardrock pegmatite raremetal granite deposits representing vast lithium resources 88217 mt li2o however the identified potential remains largely untouched which is partly due to a reluctant attitude towards primary li mining in europe europeans are very enthusiastic about evs but rather less so about the necessary mining refining of libearing ores to realise them by upscaling and integrating results from earlier projects exceeds 15 partners develop a new mining paradigm ie zerowaste multimetalmineral mining this will be combined with sustainable mineral processing to provide us with additional critical raw materials crms rare earths nb ta w be and industrial minerals quartz feldspar and micas coming from 4 lithium mines as case studies in finland keliber portugal savannah france imerys and the uk imerys the project adopts a mineralcentric integrated methodology based on an innovative predictive and forensic geometallurgy supported by enhanced inline characterisation tools and the development of digital twins exceed develops upscales and demonstrates costeffective sustainable and responsible extraction routes for recovering crms and industrial minerals the latter for use as lowcarbon ceramics and cements as byproducts from the 4 libearing hardrock ores exceeds longterm impact includes the replication of the exceed solutions to the other 23 european pegmatite and raremetal granite deposits thus boosting domestic crm production up to 217 mt li2o 15 mt of other crms in a way that gains public support by respecting the environment and creating local jobs
vision optics with integrated vcsels and autofocal lenses

intelligent devices like smartphones pcs smart watches cars and machines require active visual attention and manual interaction of the user for operation and control such as by touch screens this is not convenient for many applications and also causes user distraction which may be not acceptable for safety critical situations that require full visual attention eg driving health applications or control of machines eyetracking et systems integrated into smart glasses can use parameters like gaze direction or motion of the eye and the eyelid to control the device et can therefore pave the way for completely new handsfree human machine interfaces hmis suitable not only for critical applications but also in general for a more comfortable user interaction eg for consumer devices industrials applications or education however conventional camerabased et systems suffer from high costs complexity high weights and dimensions as well as sensitiveness regarding ambient conditions therefore et is currently applied for some specific use cases but has yet not reached broad market acceptancethe viva project will develop the technologies to enable a new class of eyetracking systems which will be lightweight small power efficient fast reliable and highly accurate under nearly all ambient conditions the project will integrate and further develop novel sensors based on laser feedback interferometry small and light metaoptics as well as ai methods and hardware for signal processing and feature detection the overall eyetracking system will be verified and demonstrated by typical use cases along with these developments the new et technology will be analyzed regarding privacy data security safety and ce conformity all in all the outcome of viva will leverage the market breakthrough for smart glasses with eyetracking and will enable the eu economy to gain the technological lead for the next big thing regarding hmis for smart devices
fostering and enabling ai data and robotics technologies for supporting human workers in harvesting wild food

wild berries and mushrooms are considered to be a national treasure of nordic countries these food products require zero resources to cultivate as they grow naturally in the forests it is estimated that less than 10 of the total annual wild berry crop is harvested from the forests the main challenge in collecting wild berries lies in the manual forest harvesting namely pickers working conditions due to the short season the majority of the work is conducted by foreigners with limited knowledge of the language culture and forests the ferox project aims to utilize advances in ai data and robotics to improve the working conditions of the wild berry pickers the project will employ autonomous drones equipped with various sensors to acquire data build 3d models of the forests and therefore accurately estimate berries locations amount and types the collected data will be used to build ai models to help workers locate the berries and optimize their operations in addition ferox will provide wild berry pickers with navigation and locating services and physical support to improve their working conditions and boost their trust and confidence the holistic solution of ferox will contribute to the overall safety of the workers by automatically monitoring the pickers and providing aid where it is needed as a consequence ferox is expected to attract locals and hiking enthusiasts to work during summer in collecting wild products hence increasing the overall yield of the wild berries these outcomes will open business opportunities for eu companies to adapt the solutions developed for industrialized cultivation as well as support global sustainability as technology providers for safe and sustainable berry harvesting to demonstrate the solution ferox will conduct its tests in the forests in finland with the support of the wild berries and mushroom arktiset aromit arctic flavours association
transdisciplinary methods for societal impact assessment and impact creation for security research technologies

current european research and innovation ri and security policies aim to address challenges that threaten european societies by deploying security technologies security technologies are typically intended to promote public safety security and increase societal resilience at the same time security technologies spur controversies and can have enormous societal legal ethical economic and political impact such technologies often infringe human rights reproduce and reinforce power imbalances and social injustice civil society is rarely or restrictively involved during research and development of security technologies and thus societal concerns might not be well addressed in this process security technologies and ri should not create societal mistrust or missed opportunities to jointly build societal resilience transcend aims to improve practices of citizen and societal engagement in security ri to enable individuals and organisations that speak on their behalf to participate actively and creatively in iterative processes of design and deployment transcend will develop a toolbox of methods to enhance the involvement of civil society in security ri the toolbox will be tested and evaluated in four pilots in close collaboration with diverse on the ground organisations by bringing together transdisciplinary actors from academia government industry and society quadruple helix the transcend framework will present guidelines on how to design and structure meaningful civil society and public engagement for societal impact assessment for security research technologies and present domainspecific instructions for the use of the transcend toolbox transcend will contribute to the uptake of effective methods for citizen and societal engagement throughout the eu so that civil society are given a louder voice a place at the right tables and security practitioners are motivated and equipped to enhance such participation
adaptive optical metasurfaces for realtime labelfree and nondestructive 7d digital pathology

treatment decisions for many pathological conditions including inflammatory degenerative autoimmune infectious diseases and cancer are largely based on microscopy study of the surgically excised tissue specimens histology optipath provides a new paradigm for gathering objective optical tissuedependent data which is essential to overcoming the diagnostic challenges of interobserver variability and limited sensitivity and specificity optipath will offer nondestructive labelfree realtime 3dpresentation of tissue samples this is enabled by i revolutionary nanophotonic optical metasurfaces oms for simultaneous singleshot acquisition of spectral and polarimetric information and adaptive oms actuated by thinfilm piezoelectric microelectromechanicalsystems mems for ii rapid vector vortex beam vvb shaping of light and iii rapid confocal 3d imaging the wealth of objective diagnostic data provided will be interpreted using machine learning ml deep learning dl and is essential to overcome interobserver variability in diagnosis and provide actionable insights to the clinician by utilizing optical markers present in unprepared tissue histological procedures can be dramatically sped up offering realtime diagnosis in operation theatres and pathology departments by offering timely and accurate diagnosis optipath will enable early diagnosis and improved prognosis of recovery
resilient cultures music art and cinema in mainland china and hong kong

how to be critical in a context where critique is disavowed how to speak against power while being silenced how to stay amidst suppression rescue studies how cultural practices in the domains of popular music contemporary art and queer cinema in mainland china and hong kong develop resilient tactics to express their social and political discontent it theorises resilience and cultural critique in times of intensified authoritarianism and rapid platformization whereas such practices can resort to a history of experiences in china to negotiate a recently intensified authoritarianism cultural practitioners in hong kong are facing a compressed authoritarianism still searching for resilient tacticsrescue studies indie music in hong kong folk music in china the role of official and unofficial art institutes in china and hong kong socially engaged art projects in rural and urban areas in china and hong kong and queer cinema and queer film festivals in china and hong kong it develops a relational comparative analysis between different cultural fields and at different localities hong kong beijing shanghai guangzhou tianshui to unpack the impossibilities of critique rescue develops an innovative methodological toolkit combining ethnography with textual analysis digital methods and collaborative research rescue will establish and consolidate a network of academics cultural practitioners and activists in mainland china hong kong east asia and europe through multiple workshops a podcast series performances screenings and an exhibition thereby increasing the social impact of the project findings will not only attest to the multivocality diversity and vitality of cultural production in mainland china and hong kong thus pushing back against the idea of the omnipotent chinese state but also inspire and forge connections to other localities facing a comparable predicament eg brazil hungary india russia and turkey
twinning microplasticfree environment

greenland is an innovative strategy for transforming to a digital cloudbased system with the education of staff for research of microplastics in soil water and microorganisms as well as networking with the excellent institutions and stakeholders who are interested in the results of scientific research the essence of greenland is to change the system in which a great contribution will be made to the planet without plastic by working on preventive measures innovations and a plan for remediation trained professional staff will be able to be more efficient with the help of new digital tools which will result in the establishment of strong cooperation with institutions and industry
development of a multilayered and bioprinted ipscderived retinal model with use in preclinical and toxicological testing

agerelated macular degeneration amd encompass the most prevalent cause of visionloss in elderly people in developed countries one of the main hurdles restraining the development of efficient treatments against amd is the inability of current animal 2dcellular and organoidbased models to completely recapitulate the pathophysiology of this disease the goal of the iretina project is to bioprint an invitro human retinal model using isolated endothelial and retinal cells derived from ipscs the result will be a functional and vascularized ipscderived tissue resembling the native stratified retina that could serve as a preclinical and toxicological model for drug development and for the study of complex phenomena such as allogenic immune response in order to achieve this goal the iretina project will focus at three different levels 1 implementing stateoftheart genome editing tools for the development of retinal cell differentiation and enrichment strategies from healthy and amdpatient ipsc 2 developing new methodologies for bioprinting endothelial and retinal cells aiming to preserve cell viability synaptic connectivity and structural integrity 3 proof of concept testing to evaluate the usefulness of the artificial retina as a bona fide in vitro retinal model the nature of this project is strongly multidisciplinary and involves the collaboration of basic researchers with experts in the fields of ophthalmology immunology and biomaterial sciences the results of this proposal have the potential to represent a true technological and scientific breakthrough that will result in better organ and disease modeling and reduced laboratory animal use eventually minimizing the burden and complexity of preclinical trials required for the development of novel pharmacological and cell replacement therapies against amd
an automated platform for the largescale production of miniaturized neuromuscular organoids

organoids have been developed as advanced 3d cell culture systems that resemble aspects of the in vivo tissues and provide an alternative to study the mechanisms of human disease and identify novel treatments the last years have witnessed tremendous developments in the field of stem cell and organoid research but the full potential of these systems remains to be exploited two major challenges facing the organoid field are reproducibility and scalability the manual production of organoids is a laborintensive and expensive process the development of costeffective fast and reliable methods is a prerequisite for transferring organoid technologies to the industry for highthroughput approaches we have recently established a novel complex human neuromuscular organoid nmo model from human pluripotent stem cellderived neuromesodermal progenitors nmos selforganize into spinal cord neurons and skeletal muscle compartments that contract by forming functional neuromuscular junctions the erc consolidator grant gpsorganoids focuses on the generation of positionspecific gps nmos representing distinct spinal cord segments and the use of such nmos models to study the selective vulnerability of specific spinal cord neurons to neuromuscular diseases like amyotrophic lateral sclerosis and spinal muscular atrophy the poc grant goes beyond the scope of our erc consolidator grant and focuses on the commercialization of the nmo model through the establishment of an automated reliable and high throughput production line that could apply to industry settings our ultimate goal is to establish nmos as a leading model in the market for high throughput drug screening approaches and accelerate the development of novel therapies for neuromuscular disorders
distorting unconventional superconductivity a grasp of electronic phases with multiple broken symmetries

when electrons in a solid interact strongly they can form novel states of matter with fascinating technological possibilities and intriguing intellectual challenges they might realize the macroscopic quantum state with dissipationless transport superconductivity or spontaneously lose spherical symmetry an electronic nematic state surprisingly more and more nematic superconductors combining both have recently been discovered such observations suggest a fundamental link between nematicity and superconductivity that is not yet understood progress is hindered by an acute lack of systematic data on the nematicitysuperconductivity interaction due to the absence of routine highresolution probes of nematicity that are applicable in the superconducting state accurately determining lattice distortions and elastic moduli would be suitable but the corresponding classic techniques are not possible or practical for many novel materialsto relieve this scarcity of knowledge i propose to establish a novel distortiometry approach based on measuring a materials elastic response to anisotropic stress taking full advantage of established capacitance dilatometry and recent advances in straintuning techniques the approach will be at the center of a specialized program based on distortions to get a grasp of nematic superconductivity having confirmed the new methods versatility resolution and reliability i will study several platform materials where nematicity and superconductivity interact in the context of quantum criticality investigate novel topological materials whose superconductivity appears to be nematic itself and explore new nematic superconductors thus i will gain new insights into mechanisms of unconventional superconductivity and its multiple degrees of freedom my new widely applicable techniques will be a powerful addition to the arsenal of experimental solid state physics and material science
hidden cascade modelling for the identification of hidden tip chains in stock markets

consider a scenario in a financial market where investors privately share important insider information within their social circles although financial authorities could monitor investors transactions it remains challenging to identify which investors have received and are exploiting insider information i term this scenario a hidden cascade problem in which the true states of agents cannot be directly observed this particular form of cascade modelling involving the inference of agent states from indirect observations has received limited attention in the existing literaturethis proposal hiddentipchains introduces approaches based on topological data analysis machine learning and probabilistic modeling to reveal hidden information transfer through investors social connections and to detect suspicious trading based on insider information this supports european commission goals for financial stability and investor protection in a broader context the methods will enable us to analyse hidden cascade models when direct observations of agents true states are not directly observable i expect that in future research these approaches can find application in addressing hidden cascade challenges across various fields such as epidemiology climate science and information securitythe empirical part of the project is based on worldwide unique and exceptionally extensive datasets providing us with full access to investors full marketwide trading history on all the securities they traded additionally we have observable social connections among insider investors allowing us to track how news tips about future events propagate within this network the approached developed in this project will be verified with synthetic data with extensive montecarlo experiments the project contributes to the computer science literature by developing techniques for hidden cascade problems and within the quantitative finance domain for identifying market abuse
sequencestructurefunction uncovering how genetic variation at human centromere drives cellular phenotypes

the last decades have seen an extraordinary leap in our knowledge of the human genome and its role in health and disease yet approximately 5 of our dna still lacks sequence annotation and has been largely excluded from functional and diseaseassociation studies these genomic gaps include dna repeats such as centromeres which are large tandem arrays of alphasatellite dna centromeres chromatin is functionally essential for chromosome segregation serving as the basal template for the mitotic kinetochore a recent breakthrough has been the complete genome assembly including centromeres of a haploid cell line derived from fetoplacental growth of a molar pregnancy however centromeres sequence and size vary across tissues between individuals and in disease states the main challenges are to understand how is centromere variation generated and especially the consequences at a functional level the specific objectives of my project are 1 identify the mutagenic processes and dna repair responses operating at centromeres 2 determine the impact of centromeres sequence variation on chromatin structure kinetochore function and chromosome behavior and 3 understand how these changes contribute to genome instability cellular phenotypes and disease predisposition the originality of this project is to follow a multidisciplinary approach that combines experimental studies spanning structural biochemistry to cell biology and bioinformatic analyses that will benefit from the information on centromere reference already available and soon to be generated the proposed research therefore represents a very appropriate and timely contribution to provide an integrated view of human centromere variation and its role in determining phenotypic traits furthermore it will provide important insight on the functional role of the missing genome in human diseases and promises to yield key information and tools for expanding this novel field