Dragon09/odtu_chatbot huggingface dataset:
impact of mpxv infection on pregnancy outcome and newborn health

pregnant women have an increased risk of severe mpox disease however the underlying mechanisms remain elusive to better understand altered transmission pattern of mpxv and its impact on this vulnerable population pregmpox aims to assess the extent of mpxv spreading among pregnant women in south kivu and neighboring regions through both passive and active surveillance passive surveillance will utilize existing health data from local facilities capturing reported cases while active surveillance will involve direct community engagement to identify and document unreported cases in sentinel study sites in hot spot areas the prevalence of mpxv infection among pregnant women will be investigated and potential transmission routes determined moreover our project aims to document and analyze adverse pregnancy outcomes associated with mpxv infection such as spontaneous losses stillbirths preterm deliveries and neonatal infection mpxv pregnant women will be asked to participate in a cohort study where they will be followed until delivery to document pregnancy outcomes maternal immune response and virus abundance and pathological changes in the placenta this will help to determine specific risk factors and modes and frequencies of vertical transmission to the unborn and generate a list of clinical and immunological predictors for adverse outcomes for pregnant women and neonates as a prerequisite to evaluate the safety of the mvabn vaccine and tecovirimat treatment in pregnant women we will create a comprehensive register of adverse pregnancy outcomes using a pharmacovigilance model to monitor and analyze adverse events following immunization and treatment the results of our multidisciplinary studies will be crucial for developing guidelines and recommendations to manage mpox more effectively during pregnancy and for potentially influencing global health policies
performing lyric east and west a comparative study of the ancient greek and japanese traditions

this project proposes the first comparative analysis of ancient greek and classical japanese performed lyric poetry n ever to be undertaken it will explicate the fragmentary greek lyric poetry as textual traces of a now extinct performance tradition against the still living japanese lyric performance tradition that is n harnessing the insights of cognitive performance studies in so doing it will produce a proof of concept for the comparison between greek lyric and n a demonstration of the application of novel approaches drawn from cognitive performance studies to both the greek and the japanese material a novel set of comparative readings for the benefit of both classicists and japanologists and an impetus for renewed dialogue between scholarship and performance practice the successful completion of this project will establish me as a comparatist in addition to a classicist extending my scholarly reach beyond my native discipline and even beyond the academic world by allowing me scope for engagement with the performing arts and the public at large the research will be carried out in universities in japan and italy straddling the respective departments of classicshumanities and japanese and comparative literatureasiatic studies at the university of tokyo and ca foscari university venice
incoming marseille22

the aim of this project is to organise the marseille conference for international cooperation inco under the upcoming french presidency of the council of the european union during the first semester of 2022 this twoday marseille ministerial conference being held on the 8th and 9th of march 2022 is an ambitious initiative to promote a global approach for research and innovation the event aims at fostering exchanges and good practices setting off a new cooperation framework with partners based on the european unions values and objectives this one of a kind initiative will encourage europes global approach towards research and innovation this csa will be managed by ird french national research institute for sustainable development and will contribute to the success of the marseille conference which shall involve delegates both european and international along with selected external experts as monobeneficiary of the grant ird will liaise with the mesri the french ministry of higher education research and education and the meae the french ministry of europe and foreign affairs for the overall organisation of the conference these two days shall be hosted across two different venues the famous palais du pharo conference centre and the mucem museum premises muse des civilisations de leurope et de la mditerrane in marseille south of france
the drought impact on the climate benefit of carbon sequestration

increases in atmospheric co2 have resulted in significant changes in global climate and ecosystem processes it is well known that the terrestrial biosphere fixes large quantities of carbon from the atmosphere still less certain is whether soil and terrestrial vegetation can mediate the increase in co2 and for how long carbon storage largely depends on water constraints and climate models predict drier future conditions particularly in the mediterranean although droughts are associated with reductions in photosynthetic rates their effect on the role of forests in climate change mitigation is still unclear the drought impact on the climate benefit of carbon sequestration project aims to advance understanding of the impact of soil moisture on forestsavoided warming and for how long it occurs by achieving three objectives i simulate the effect of drought on the global terrestrial biosphere c cycle under global warming scenarios ii develop a mechanistic model based on experimental observations to represent the carbon cycle dynamics under drought conditions in a mediterranean forest and iii compare the warming produced by co2 emissions and that avoided by mediterranean forests under drought scenarios these objectives will permit answering whether the climate benefit of c sequestration is sensitive to drought conditions on a global and local mediterranean scale and whether mediterranean forests mantain their offset co2 emissions under these conditions the above will be carried out by linking photosynthesis storage and respiration processes through the combination of transit time carbon sequestration and the climate benefit of sequestration concepts with measurements from a unique longterm drought experiment the compartmental system approach and global carbon cycle models this project will result in relevant scientific contributions and a valuable and comprehensible tool to enhance policyoriented discussion on naturebased climate mitigation
exploring neuroglymphatic coupling during sleep using wearable technology

in recent years it has been demonstrated that sleep not only plays a crucial role in cognitive emotional and immunological functions but also helps to clear the brain from metabolic waste products via the recently discovered glymphatic system a physiological marker closely associated with glymphatic clearance is electroencephalographic eeg slowwave activity swa 14 hz an increase in swa driven by high sleep pressure accumulated during the day is related to a boost of glymphatic clearance in humans such temporal neuroglymphatic coupling has been confirmed by using a combination of sleep eeg and functional magnetic resonance imaging fmri which however is challenging to use in sleeping subjects recently a first wearable solution has been developed that allows simultaneous assessment of brain electrophysiology and glymphatic system activity by using a combination of the sleep eeg and noninvasive functional nearinfrared spectroscopy fnirs this unique technological solution provides an opportunity for the investigation of neuroglymphatic coupling in sleep without disturbing natural sleepswa can be boosted by the welltimed presentation of brief auditory stimuli during sleep without otherwise altering natural sleep architecture this approach is referred to as closedloop auditory stimulation clas and has gained a lot of attention from both sleep researchers and the industry given that deep sleep is a primary driver of glymphatic clearance it is of great importance to establish if clas can boost glymphatic activity along with swa enhancement evidence for the modulatory effect of clas on glymphatic clearance will open new avenues for future implementations of clas for prevention andor therapy of neurodegenerative disorders for instance the regulation of glymphatic clearance might be of high clinical relevance in alzheimers disease characterised by reduced glymphatic convection causing harmful protein aggregation
the early exploitation of cetacean in western europe during the late upper palaeolithic

the whalebone project builds upon new advances in the study of past human adaptations to coastal environments focusing on a key case study early interactions between late upper palaeolithic foragers and cetaceans at the end of the last glaciation in western europe over the last decade a growing body of evidence suggests that the exploitation of whales could have been one of the significant factors underlying the development of early coastal economies during the magdalenian culture between 18000 to 15000 years ago the recent identification of 54 whale bone artefacts in the cantabrian region northern spain during the previous postdoctoral research of the pr to which can be added the 109 previously known pyrenean examples revealed the existence of regular and structured communication networks for the longdistance circulation of these marine resources however these studies focused only on the bay of biscay and it is still unclear whether this phenomenon was a strictly local adaptation or was part of a wider shared coastal economy connecting different parts of europe to test this hypothesis whalebone proposes to identify cetacean bone objects outside the pyreneocantabrian region focusing on the spanish coasts as many magdalenian sites are close to the paleoshorelines that yielded rich osseous industries the mediterranean coast is a particularly crucial area of investigation direct dolphin bones and indirect whale barnacles evidence for the exploitation of cetaceans in its southern part confirms the early interest and management of marine mammals a multiproxy approach beyond traditional zooarchaeology including the first use of an innovative ancient proteomic technology zooms together with a minimally invasive dating program of cetacean bone objects will be undertaken by whalebone in order to address longstanding questions about longterm forager mobility patterns regional interactions and coastal adaptations on a european scale
innovation in supercritical co2 power generation systems

the primary objective of this fouryear work programme is to undertake cutting edge multidisciplinary research and development to make a step change in understanding of supercritical co2 based power generation systems technology and its potential to enable a step change in thermal energy power cycles to be a major contributor to achieving the 2050 zero emissions targets while providing specialised training for 15 doctoral researchers to help establish the backbone of an important industry the technical objectives of this research are 1develop advanced models and design tools that enable the optimal integration of sco2 power systems components for various thermal energy sources and end use applications 2develop accurate prediction tools for the simulation of transient operation of sco2 power cycles and investigate innovative concepts of control and optimisation of operation3develop innovative methods to enhance aerodynamic and mechanical performance reliability and operability of key system components4develop advanced modelling and experimental methods that enable selection and development of materials coatings and manufacturing techniques to achieve the objectives of this training programme effectively isop proposes four research wps and requests funding from the eu for 15 doctoral candidates for a total of 540 person months who will work on an ambitious plan to advance the sco2 power cycles technology beyond the stateoftheartthe project aims to contribute to the eu agenda on european research area by training a new generation of creative entrepreneurial and innovative earlystage researchers who can face future challenges and to convert knowledge and ideas into products and services for economic and social benefit in addition support to and compliance with the united nations sustainable development goals will be at the heart of the training of the doctoral candidates and the scientific and economic outcomes of this research
search for new physics and technological advancements from neutrino experiments at the high intensity frontier a cooperative europe united states brazil effort

sense promotes the collaboration among european american and brazilian researchers involved in the most important research projects in the field of neutrino physics at the high intensity frontier the observation of neutrino oscillations established a picture consistent with the mixing of three neutrino flavours in three mass eigenstates and small mass differences experimental anomalies suggest the existence of sterile neutrino states participating in the mixing and not coupling to the sm gauge bosons lepton mixings and massive neutrinos offer a gateway to deviations from the standard model in the lepton sector including charged lepton flavour violation the fnal shortbaseline neutrino sbn program based on three almost identical liquid argon time projection chambers located along the booster neutrino beam offers a compelling opportunity to resolve the anomalies and perform the most sensitive search for sterile neutrinos at the ev mass scale through appearance and disappearance oscillation searches microboone icarus and sbnd will search for the oscillation signal by comparing the neutrino event spectra measured at different distances from the source the fnal sbn program is a major step towards the global effort of the neutrino physics community in realising the deep underground neutrino experiment dune which will provide fundamental contribution to the determination of neutrino mass ordering measurement of cp violation precision tests of the threeflavor oscillation paradigm using longbaseline flavor transition search for nucleon decay and study of the burst of neutrinos from corecollapse supernova in the framework of multimessenger astronomy sense researchers have provided major contributions to the sbn and dune projects and will take leading roles in the commissioning of the detectors data taking and analysis these endeavors foster the development of cuttingedge technologies with spinoffs outside particle physics
lightdriven catalytic processes for the stereoselective functionalisation of csp3h bonds

one pressing challenge is to develop new sustainable processes to convert abundant chemicals into addedvalue chiral products thus using natural resources responsibly the lighthat project seeks to provide solutions by developing innovative stereoselective transformations that use abundant substrates including feedstock and naturally occurring molecules we will achieve this goal by combining advanced concepts of asymmetric catalysis such as metalbased cross coupling and organocatalysis with photochemistry specifically we will directly functionalise carbonhydrogen ch bonds the most abundant moiety in organic molecules to enable onestep access to complex chiral molecules from readily available ch substrates including alkanes and natural products to achieve this we will use lightactivated catalysts that via hydrogen atom transfer hat mechanisms can selectively activate strong unactivated csp3h bonds at sites that are unreactive for traditional methods the project will benefit from a collaboration with bayer ag which will aid in identifying suitable biologicallyrelevant ch substrates to be employed in the developed processesthe planned research combines perfectly the fellows experience in metal catalysis and radical chemistry with the hosts experience in lighttriggered asymmetric processes lighthat brings a new industrial collaboration to the host institution and transfers knowledge of advanced techniques in asymmetric organocatalysis and photochemistry to the candidate contributing to sustainability and european excellence an ambitious training program will transfer several new scientific and soft skills to the applicant the projects intersectorial nature will broaden the fellows competencies and place him in a competitive position for his next career move
upscaling deep conversion routes for hardtorecycle biogenic waste

as prevention strategies are struggling with respect to some waste categories biogenic hardtorecycle streams represent a critical issue hindering circular bioeconomy and resulting in severe environmental pollution phenomena the waste framework directive and the eu green deal indicate the need for developing pioneering value chains to address the challenge in compliance with sustainability targets a set of promising thermochemical processes emerged both in dry pyrolysis gasification and wet aqueous hydrothermal carbonisation hydrothermal liquefaction phases with their application still limited by technical and nontechnical barriersthe upcycle dn will train the next generation of professionals in the upscaling of these deep conversion technologies for hardtorecycle biogenic waste and will provide innovative tools for the design of feasible waste upcycle solutions to highvalue secondary materials such ambition will be achieved by developing an integrated methodology combining cuttingedge experimental and modelling techniques at various scales molecular reactor and process and by covering the entire value chain in continuity with relevant stakeholders several priority waste streams will be targeted namely highly contaminated and poorly reactive sewage sludge and derived products from municipal and industrial wastewater treatment as well as highly contaminated lignocellulosic materials the upcycle partners will work synergistically to generate a cohort of 15 welltrained young researchers with a unique multidisciplinary set of skills not limited to technical ones with the goal of making them the future research leaders or entrepreneurs capable of bringing forward a paradigm shift at once the project will pave the way for largescale deployment of sustainable technologies on which a new generation of biorefineries could rely
nonlinear interaction of terahertz light with twodimensional nanomaterials

twodimensional 2d nanomaterials such as graphene and transition metal dichalcogenides tmds hold great promise for the engineering of modern nanophotonic devices that will operate at terahertz thz speed rates with reduced energy requirements particularly their nonlinear properties at thz frequencies are expected to be the key element for the development of thz nanodevices that can generate new frequencies control light propagation or act as nonlinear optical modulators the terananolight project aims to study with nanometer spatial and femtosecond temporal resolution the ultrafast interaction of 2d nanomaterials with atomically strong multimvcm thz fields promoting the lightmatter interactions into the nonperturbative regime intense thz transients will be combined with a scatteringtype scanning nearfield optical microscope snom to achieve atomically strong fields initially thz surface plasmons sps will be resonantly coupled in graphene and their nonlinear behavior will be studied by monitoring their formation propagation and temporal evolution as the thz field strength increases into the nonlinear regime furthermore nonresonant nonlinearities will be explored exploiting the oscillating thz field as an ultrafast ac bias the possibility to observe high harmonic generation hhg with characteristics similar to those of atomic gases will be studied in monolayer tmds and heterostructures of different layers number and twist angles excited by an outofplane polarized thz field finally the opportunity of exploiting the extremely nonlinear interaction of light with matter to improve the spatial resolution of snom will be investigated terananolight project envisions to facilitate our understanding about the ultrafast interaction of intense thz light with 2d materials and their highorder nonlinearities this understanding is expected to trigger innovative research on the development of the future thz lightwave electronic devices
implacable archives reviving mrio pinto de andrades personal archive

luarc intends to contribute to the enhancement and revitalization of the personal archive of angolan intellectual mrio pinto de andrade mpa in addition to working with unique documents luarc develops an interdisciplinary approach to the archive as a site of production of historical knowledgewidely known for his participation in the angolan liberation struggle mpa is a key figure in the cultural history of angola and one of the most important contemporary african intellectuals luarc focuses on the vast and heterogeneous material that the writer collected between 19401990 following the life of mpa and that of angola through the late colonial period the anticolonial struggle and postindependenceluarc puts together academic institutions and nonacademic organizations located in portugal angola and the us creating international connections to animate meaningful debates on angolas recent past the project uses methods and techniques of archival science and digital humanities to ensure the proper appreciation of mpas personal records treating data according to the best ethical practices luarc grants broad open access to the digital archive as well as to other project results and outputsstrongly rooted in history and postcolonial theory luarc situates the archive in the context of angolas transition from colony to independent nation creating a framework in which personal records come to make meaning as parts of a complex collective history in particular records are analysed in order to trace the evolution of practices and discourses on culture and nationalism in angola bringing to the surface narratives that have often been neglectedat the same time drawing from literary studies and archival art luarc reflects on the practice of producing and keeping records understanding it as a performative act that intervenes in the creation of the narratives through which we come to make sense of the past