Dragon09/odtu_chatbot huggingface dataset:
supporting research ethics committees for efficient functionality and national accreditation to review clinical trials in uganda and ethiopia

backgroundthere are few research ethics committees recs with capacity to review and provide oversight for clinical trials in subsaharan africa ssa and hardly any national accreditation systems used to evaluate the quality of review by these recs although digital protocol submission systems improve recs efficiency up to 48 recs in ssa still use paperbased systems additionally many single country clinical trials in ssa are not registered with any internationally recognized clinical trials registry the secret project seeks to address these challenges in uganda and ethiopia by establishing national recs accreditation systems building capacity of recs to review clinical trials including during outbreaks and emergencies establishing national clinical trials registries linked to the pan african clinical trial registry pactr and developing digital protocol submission systemsmethodologythe secret project includes partners that have worked together in other edctpfunded projects to address the identified gaps through four objectives and six work packages we will leverage the experience of the uganda national accreditation system to establish a national accreditation system for ethiopia and accredit at least two recs in ethiopia and two in uganda we will also leverage the expertise of the pactr to set up the uganda national clinical trial registry nuvoteq that have experience in digital solutions for health care services will support ethiopia to setup the digital protocol submission systems we shall also leverage the expertise of makerere university bioethics training unit and the national drug authority of uganda to build capacity for clinical trial review and oversight for the recs to be accredited the uganda national health research organisation and institute of tropical medicine in antwerp which are the coordination institutes have worked together on alerrt an epidemics preparedness consortium funded by edctp
european researchers night and researchers at schools 20242025 in malopolska

the project has been organising in our region for 17 years the european researchers night ern will be implemented in 2024 27th september and 2025 26th september for the 18th and 19th time researchers at schools activities will be implemented for the 3th and 4th time all the project activities will be organised under the slogan superherosresearchers save the world with this tagline and reference to the ideas and characters of superheroes known to everyone especially children and young people we want to draw the publics attention more strongly to the role played by scientists in the development of the world in the fight against environmental and climate threats and how inventions affect our everyday lives these are the key areas defined as eu research and innovation missions and the objectives of the european green dealthe main goals of the project are to bring science and the profession of researchers closer to the general public and make the public more aware of the impact of the work of researchers on our daily lives to develop interest in research and scientific careers in the youthscale of the project is huge to show the wide scientific heritage and achieve projects goals ern 20242025 each year ca 2000 activities organised incl interactive workshops demos and experiments face to face meetings with researchers science shows etc ca 2200 researchers emploees and students as well as 110 scientifis circles from 60 institutions involved ca 50000 people will participate in each ern researchers at schools activities in 20242025 700 workshops demos and meetings with researchers 240 scientistsworkers and students involved 25000 pupils and 800 teachers from 270 polish schools will benefitthe project has european dimension due to its broad awareness campaign we estimate that 7 million people will be made aware of the project every year
digital maintenance for sustainable and flexible operation of hydropower plant

dihydro contributes towards harnessing the full potential of hydropower hp plants and clusters in line with the objectives of the european green deal and the paris agreement by development of tailored optimized digital and smart decisionmaking tools for use in such plants at scale indeed dihydro will develop smart devices and proactive intelligent algorithms that utilize data acquired from static dynamic and alternative sources eg satellites so as to predict the operational and maintenancerelated behavior of standalone hp plants and clusters and we will then incorporate such algorithms in digital twins that can fully interrelate with such hp plantsclusters yielding eventually an intelligent fullyreplicable decisionmaking tool for optimal coordination of environmentally mindful power generation from such plantsclusters based on the foreseen market needs and the intended commercial strategy of their owners notably a wide variety of previous plant digitization levels weather and water flow conditions biodiversity environmental and societal issues pertinent to such hp clusters are incorporated in the integrated practical solution developed here mainly by leveraging innovative sensor technologies cuttingedge digital adaption for energy production and optimized operation and maintenance practices based on nextgen information technology the consortium is comprised of 13 partners 3 of which are rtos 7 smes and 3 large power enterprises represented here by their hydropower branches
the role of shared micromobility modes in the resilience of urban transportation systems new challenges and opportunities

increasing urban traffic and environmental challenges have driven the investigation development and diversification of sustainable transportation alternatives globally the resilience of these alternatives has also been considered equally important in recent research in order to ensure a more safe accessible and equitable transportation system during severe disruptions however there is a lack of comprehensive evaluation system through which urban and transportation planners can assess and plan for transport resilience in their own geographical contexts in this regard this research proposes a model to evaluate an overall resilience of shared micromobillity systems through their commonly available usage patterns in light of current challenges and future opportunities specifically it takes major shared micromobillity programs eg stationbased bikesharing sbbs freefloating bikesharing ffbs freefloating ebike sharing ffebs and freefloating escooter sharing ffess operating in europe as examples to empirically analyze the mobility patterns of their users across three timescales before during and after the pandemic as a methodology this study will utilize a combination of quantitative and qualitative techniques the expected outcomes will help in improving governance and an appropriate appraisal of sustainable urban transport alternatives which are still in its infancy the resilience assessment tool will further help develop longterm systems for measuring and executing mobility plans on both sides of the mobility equation supply and demand
understanding vaccination hesitancy and evaluating single dose and genderneutral vaccination for improving uptake of hpv vaccines in west and east africa

cervical cancer caused by human papillomavirus hpv is almost entirely preventable through prophylactic hpv vaccination many countries have yet to implement hpv vaccination programmes or are struggling to achieve high vaccine coverage this presents a major challenge for meeting the world health organisation who cervical cancer elimination target with 90 of 15 yearold girls being vaccinated against hpv by 2030 originally licenced as multidose vaccines who has recently recommended that countries can offer a single hpv vaccine dose to 920 year olds the improvehpv consortium a partnership of research institutions in tanzania nigeria uk and spain will investigate barriers to hpv vaccine uptake and the impact and acceptability of new hpv vaccine delivery strategies to improve vaccine coverage and effectiveness and reduce hesitancy the consortium builds on previous successful collaborations in hpv epidemiology and vaccine research and qualitative research on barriers and facilitators to vaccine uptake tanzania has a multidose hpv vaccination programme in girls but will change to a single dose regimen in 2024 a genderneutral hpv vaccination strategy is currently being implemented in tanzania as part of a large clusterrandomised trial nigeria is one of the first countries to introduce national hpv vaccination with a single dose using these opportunities improvehpv will evaluate vaccine effectiveness uptake and the factors affecting acceptability of 1 hpv twodose vaccination delivery in females 2 introducing or changing to a single dose vaccine regimen 3 genderneutral hpv vaccination and will also 4 investigate factors influencing vaccine hesitancy community engagement and perceptions of hpv vaccines the workplan directly addresses effectiveness and uptake of different hpv vaccine deployment strategies through phase ivimplementation research and will inform policy decision making in subsaharan africa for hpv vaccination programmes
highthroughput discovery of catalysts for the hydrogen economy through machine learning

hydrogen energy storage offers a unique combination of scalability longterm storage and portability leading to the socalled hydrogen economy the major challenge in the hydrogen economy is related to the production of hydrogen from water and the generation of energy by the oxidation of hydrogen into water in this regard the main objective of the project highthroughput discovery of catalysts for the hydrogen economy through machine learning highhydrogenml is to develop a highthroughput strategy based on first principles calculations and artificial intelligence tools to discover intermetallic compounds whose catalytic activity can be tuned to reach an optimum catalytic performance for the hydrogen evolution reaction her and oxygen reduction reaction orr by means of elastic strain engineering the successful completion of these objectives will provide unique information for experimental synthesis of intermetallic compounds with high catalytic activity for the her and orr and could therefore open a new avenue for a feasible and efficient hydrogen economy moreover the strategies and tools developed in this project can be applied later to many other catalytic processes of large industrial andor environmental interest to achieve these goals the project highhydrogenml involves multidisciplinary expertise in solid state physics materials science machine learning and chemistry that will be coupled in a seamless framework to exploit the high predictive power of ab initio calculations in conjunction with the efficiency of ml models therefore this project brings together a researcher with expertise in atomistic and materials modelling within a broad range of different computational chemistry methods and artificial intelligence techniques a worldrecognized supervisor in the area of multiscale modelling of materials and a research institute with a record of excellence technology transfer and toplevel training in materials science and engineering
elixirsteers

elixir unites europes leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research it coordinates integrates and sustains bioinformatics resources across its 23 nodes elixir enables users in academia and industry to access services databases software training standards compute provided through national nodes elixir is the esfri landmark for life science data and plays a unique role in the landscape with millions of users globally supporting the digitalneeds of other esfris and horizon europe research projects increasingly lifescience data is held at national and institutional centres thus largescale data analytics requires that researchers can find and analyse data distributed across europe the purpose of elixirsteers is to build capacity for largescale crossborder data analysis and for this capacity to be embedded across member states elixirsteers directly benefit europes life scientists by allowing software and workflows to meet requirements of those using them in national centres a robust reproducible and green approach to software and workflow provision will ensure that scientists have access to high quality energyefficient analysis tools the project will also develop the crediting and recognition systems for software supporting improvements to research assessment frameworks further elixirsteers supports elixirs longterm operations by addressing the recommendations of the european commission and esfri on the longterm sustainability of research infrastructures it will strengthen the operational excellence of elixirs nodes support the training and development of professional and scientific staff in elixir nodes expand the membership of elixir to new countries especially widening countries enable international collaborations in particular with latin america and africa and stimulate innovation and industry engagement
5g exposure causal effects and risk perception through citizen engagement

despite the rapid growth in novel applications of wireless technology comparatively little is known about their potential impacts on health in particular special attention should be paid to the most vulnerable ie young people up to 25 years old and most exposed ie workers populations the aims of goliat are to monitor radiofrequency electromagnetic fields rfemf exposure particularly from 5g provide novel insights into its potential causal health effects and understand how exposures and risks are perceived and best communicated using citizen engagement applying an integrative and transdisciplinary paneuropean approach we will i develop nextgeneration exposure assessment methods to estimate aggregated rfemf dose to the wholebody and organs in young people ii identify new occupational rfemf sources resulting from 5g deployment and estimate rfemf exposure levels and patterns in workers iii assess neuropsychological effects of rfemf in young people and workers using causal inference and iv quantify potential health impacts of exposures at the population level v assess effects of 5g on brain function thermoregulation and radical stress using in vitro in vivo human and in silico experiments vi identify effective means of exposure reduction vii better understand risk perceptions to rfemf and 5g viii apply an inclusive engagement model and codesign communication methodstools to address rfemf concerns and misconceptions ix disseminate goliats results to stakeholders and integrate them into policy actions x implement a broader analysis of the societal and ethical implications of rfemf and 5g xi develop a fair data infrastructure and xii perform activities related to the emf and health cluster the expected results will serve to deliver robust evidence on the potential effects of 5g rfemf exposure in young people andworkers and contribute to developing guidelines for exposure preventionreduction from new generation radiocommunication networks including internet of things goliat is part of the european cluster on emfs and health
unraveling the ultrafast plasma dynamics giving rise to the measured evolution filamentary structures using highresolution xray imaging

recent progress in ultrahigh intensity optical laser systems together with the advent of free electron lasers has enabled the possibility to experimentally study hot dense plasmas with unprecedented spatial and temporal resolution this early state of the plasma is prone to several ultrafast phenomena relevant for astrophysical scenarios such as gammaray bursts and plasmabased technologies such as inertial fusion energy recently thanks to the a novel highresolution xray imaging system an experimental campaign hosted at the linac coherent light source has resolved for the first time the submicron scale plasma filaments originated in the interaction of a high intensity laser with a thin solid target these results open a unique opportunity to unravel the underlying physical mechanisms behind the formation and evolution of these filaments of relevance to the aforementioned scenarios the proposed plasma advanced xray imaging project will leverage these recent developments with improved diagnostics and the help of advanced numerical simulations that will transform the exploration and quantitave identification of the main physical processes that dictate the onset and nonlinear evolution of the relativistic plasma filamentation instability this project will bring together the fields of advanced xray imaging and high energy density physics and is expected to enable the visualization of ultrafast processes in soliddensity plasmas in a similar way as optical imaging is nowadays routinely used in underdense plasmas the outcomes of the plaxi project will shed light on the extreme processes that control energy transport in gammaray bursts and fast igniting plasmas which so far could only be assessed theoretically paving the way to new plasmabased applications
nontraditional stable isotopes to track the impact of methane in earth history

over geological times the evolution of carbon isotope compositions of carbonates 13ccarb in sedimentary record highlights many positive isotopic excursions cies reflecting significant perturbations of the carbon cycle in earth surface environments although generally interpreted as a consequence of an increase of organic carbon burial in sediments the lack of high organic carbon content as well as the strong spatial and temporal variability observed in many sedimentary successions recording cies challenge this postulate among other alternative hypothesis involving regional or local control the potential influence of methanogenesis ie the biological process of anaerobic organic matter degradation producing methane ch4 has been raised its ability to generate similar isotopic signatures has been demonstrated in modern analogue although the processes behind cies are questioned providing more information about methanogenesis impact is challenging based on traditional isotopic tool like 13ccarb as its isotopic effect on is similar to that of organic carbon burial increase recently stable isotope compositions of metals used as enzymatic cofactors of ch4related processes were investigated to explore their potential as biomarkers of methanogenesis during the last decade significant advances have been made on using ni isotopes as tracers of methanogenesis but important challenges remain to better constrains both their potential and limit in order to improve our understanding of ch4 cycle and its impact on earths surface environments through geological times we will investigate further the potential of ni isotopes and its potential couplings with traditional stable isotope in various modern settings and past environments to enhance our ability to track and discriminate the influence of ch4related processes through earths history
paleolithic underwater microarchaeology

our current knowledge about human evolution is biased toward terrestrial data whereas some crucial information is stored in sitesthat are now submerged since the terminal pleistocene in dryland archaeology the combination of microevidences throughpaleobotanical geoarchaeological and experimental data has revealed new information my project aims to explore the applicabilityof these approaches for the investigation of submerged paleolithic sites by tackling two main questions1 what kind of microarchaeological materials are preserved in submerged paleolithic sites 2 why do anthropogenic microremains eg phytoliths ashpseudomorphs preserve in submerged sites with the new set of techniques phytolith morphotype and taphonomy mineralogicaland elemental analysis on thin sections and knowledge experimental archaeology paleolithic period to be learned as a globalfellow at rutgers university usa and in the interdisciplinary center for archaeology and evolution of human behaviour at theuniversity of algarve portugal i will provide a new methodological background needed to investigate submerged paleolithic sitesthe combination of microgeoarchaeology to detect submerged paleolithic sites and experimentation to explain their preservationwill yield highly relevant results the exploitation of new evidence off the continental shelf will open unique ways for the scientificcommunity while providing the base to protect our cultural heritage from sealevel rising and the exploitation of the seabed thisproject will turn me into a unique transdisciplinary and versatile underwater archaeologist at the forefront of archaeological scienceadvances with a breadth of expertise i will share practices with marine scientists paleobotanists geoarchaeologists and underwaterarchaeologists in multiple periods and regions hence preparing for my employment in tenure positions in the fields of archaeologyand marine science
delaydoppler domain communications and radar sensing

nextgeneration wireless networks are envisioned to provide high data rate and reliability with accurate sensing capability to achieve this new breakthrough in wireless technology is a must conventional wireless technologies are designed in the timefrequency tf domain where the channel response could experience significant fluctuations and the key radar parameters eg delay and doppler are not explicitly represented consequently tf domain communications generally require frequent channel estimation and large signalling overhead and the communication waveforms need sophisticated adaptions to cater to radar sensing recent advances in delaydoppler dd domain signal processing have opened the door for wireless communications and radar sensing in the dd domain leveraging the distinct channel features dd domain communications do not require frequent channel estimation moreover linear delay and doppler estimation could be possible in the dd domain thanks to the explicit representations of delay and doppler the goal of ddcomrad is to fully unleash the potential of communications and radar sensing in the dd domain by developing novel techniques for 1 dd domain multiuser multipleinput multipleoutput mumimo transmissions 2 dd domain integrated sensing and communications isac designs 3 dd domain pulse shaping and realization the main research approaches that will be employed include the advanced dd domain signal processing tool eg zak transform informationtheoretical analysis and machine learning the research outputs will have a significant impact on the applicants career prospects enabling him to obtain a leadership position in academia or industry more importantly the proposed research will not only secure the leadership of the european union eu in the 6g competition but also contribute to the economic future of the eu especially for the development of novel applications such as intelligent transportation and telemedicine