Dragon09/odtu_chatbot huggingface dataset:
problembased learning trajectories in discrete mathematics education

our research project is inscribed into the domain of mathematics education didactic of mathematics a research domain at the interface of mathematics and social sciences the project is based on the collaboration of three researchers katalin gosztonyi as experienced researcher assistant professor at the eötvös lornd university of budapest viviane durandguerrier as principal supervisor emeritus professor at the university of montpellier and simon modeste as cosupervisor assistant professor at the university of montpellier our project is focused on the development and analysis of complex problemnetworks which will then serve for the conception and implementation of problembased teaching trajectories we aim to develop an efficient modelling framework in order to construct analyse and represent problemnetworks and problembased trajectories for mathematics education both for research purposes and for supporting teachers work in planning their teaching processes we focus more particularly on problemnetworks and teaching trajectories in the domain of discrete mathematics on their potential place and role in mathematics curricula their values for conceptual learning as well as for the development of generic mathematical skills related to problem solving abstraction proof etc and their potential connections with other mathematical domains including links between mathematics and computer science a theoretical and epistemological work and a priori didactical analysis of examples of problemnetworks will be combined with experimental research on teachers and students work with problemnetworks the theoretical background of the project combines theories of the didactics of mathematics from the french research tradition with current research on the hungarian guided discovery mathematics educational tradition experiments will be realized in both countries
energy transitions in the history of economic thought 19th20th c

economic ideas play a vital role in public decisionmaking the energy sector is an emblematic case competition policies eg antitrust laws deregulation taxation emission permits and sustainablegrowth programmes all have origins rooted in economic reasoning today more than 80 of the worlds primary energy comes from fossil fuel combustion contributing strongly 75 of co2 emissions to climate change to understand the historical developments that led to this situation an indepth examination of past economic discourses concepts theories models and policy recommendations is essential this has not been done to date etranhets ambition is thus to write the first ever history of energy transitions in economic thought on a global scale etranhet will analyse how economics has dealt with energy issues and transitions since the early 19th century in diverse marketeconomy contexts 5 areas continental western europe the british isles north america latin america japan deliberately going beyond the englishspeaking literature it will perform an unusual decentring of the history of economic thought etranhet aims to characterise the contextdependency of past economic views of energy it seeks to uncover forgotten yet relevant ideas that could enrich current research into the energy transition and it intends to precisely determine how the economic discipline has been able to influence decisionmaking in energy matters etranhet is a multidisciplinary project mobilising historiographical and science studies methods to study past economists and economic thinking digital humanities and archival research will be key including the creation of electronic repositories making new valuable material available to historians by taking a fresh look at todays challenges in relation to the lowcarbon transition etranhet will contribute to show that the history of ideas has a role to play in contemporary debates on sustainability
emerging twophase expansion power generation technology unlocking the potential of geothermal and industrial waste heat utilization

geothermal energy utilization and industrial waste heat recovery are gaining recognition as valuable contributors to sustainable energy production while geothermal and waste heat sources above 150 c are commonly exploited lowtemperature sources below 150 c which are more abundant and have even greater potential for power generation remain largely untapped due to economic and technological constraints the empower consortium aims to revolutionize lowtemperature energy conversion by developing a new generation of organic rankine cycle technologies adopting a holistic approach specifically we will 1 design and analyse nextgeneration twophase turbines exploring a novel reaction configuration 2 raise the technology readiness level trl of reaction twophase turbines from trl 2 to trl 4 by validating the concept in a novel dedicated experimental facility 3 incorporate realistic twophase turbine performance data into the technoeconomic analysis and optimization of the partialevaporation organic rankine cycle systems 4 conduct a life cycle assessment lca to quantify and minimize the environmental impact of the technology in the context of geothermal energy utilization and waste heat recovery from the european cement and steel industries and 5 evaluate the social and economic benefits and barriers of deploying this technology and design strategies to exploit the benefits and mitigate the barriers the consortium consists of 7 partners 5 beneficiaries and 2 associated partners 3 academic partners and 4 industrial partners from 5 countries the consortiums composition complemented by an external advisory board with representatives from other eufunded projects and key stakeholders from targeted industries ensures a pushpull drive that will maximize progress towards our common objectives overall empower aims to deliver an emerging sustainable technology contributing to a cleaner more energyefficient future for europe
geotechnical research for space environments using an innovative tower experiment

as the number of space missions involving surface interactions increases so does the need to understand the behaviour of planetary surfaces the surface properties also are crucial for human exploration and play a key role in the evolution of planetary bodies in terrestrial geophysics and planetary exploration two techniques are widely used for insitu determination of soil mechanical properties seismic sounding and penetration testing however the gravite pi hypothesizes that these techniques are not directly applicable for space exploration due to implicit assumptions that become invalid in lowgravity environments and that this has resulted in erroneous interpretations of data from multiple space missionswhereas others use limited experimental data points numerical simulations or untested extrapolations gravite will build a unique highperformance low and variable gravity laboratory to extensively explore for the first time the complex interactions between particle size friction and cohesion in the response of granular materials to both small and large deformations under vacuum and in reducedgravity conditions the gravite facility capable of reaching gravity levels three orders of magnitude less than earths gravity in order to simulate small body surfaces and of finely adjusting the gravity level of each individual experiment will bridge an existing gap in facilities and provide exceptional experimental data covering a wide range of gravity conditions the gravite data from two custom experiments will be used to test the limits of existing theories and validate new models accounting for previously unexplored regimes as such gravite will provide the planetary science and exploration communities with much needed models that can be used to predict and interpret the behaviour of extraterrestrial surface materials the results will have direct applications to current and future space missions that interact with planetary surfaces
twinning research and innovation institutions to design and implement inclusive geps

nexus codesigns implements monitors and evaluates innovative and targeted actions aimed at bridging inclusivity gaps in nine research organisations and their respective ri ecosystems with the aim to bolster institutional change through the development of inclusive gender equality plans geps in intersectional and intersectoral directions geographical inclusiveness is also promoted through a highly contextsensitive approach to action piloting in seven member states and two associated countries covering western central southern and southeastern regions the project sets up support structures to less experienced institutions to go beyond the minimum gep requirements as defined in the horizon europe eligibility criterion through a participatory multistakeholder process of solution cocreation sustained by a twinning scheme and the delivery of a tailored capacitybuilding and training programme nexus analyses how implementing partners with newly set up geps perform data collection internal assessment and the planning of gep measures with a view to identifying areas of improvement as well as potential challenges in enhancing an inclusive approach this analysis informs the codesign and implementation of new innovative inclusive actions underpinned by the principles of intersectionality and intersectoriality nexus actions will enhance the research excellence of participating organisations as well as effecting institutional and cultural change that is contextsensitive realistic and sustainable
early detection and intervention in smoldering multiple myeloma populationbased screening and treatment

multiple myeloma mm is a bone marrow malignancy that is always preceded by asymptomatic precursor conditions monoclonal gammopathy of undetermined significance mgus or smoldering mm smm smm is a more advanced precursor and is associated with a high risk of progression to mm more than 94 of mm cases are diagnosed when already at the stage of fullblown malignancy and therefore do not benefit from the impact of early treatment recent studies indicate a benefit of early treatment but all prior smm studies are based on patients diagnosed due to other medical issues and are therefore biased there are important and urgent questions on the role of screening and early treatment in smm there is also an unmet need to develop a risk score for progression that considers the biology and genetics of the disease in editsmm we plan to build on the success from the iceland screens treats or prevents mm istopmm study where remarkably over 54 of the population n80759 consented to a nationwide screening for mm precursors it includes clinical evaluation and followup biobanking cross linking to central health data registries repeated questionnaires on patient reported outcomes groundbreaking methods of detection of smm and indepth genetics editsmm will identify all patients with smm diagnosed in istopmm these will be followed and treated with the global objective of inducing a paradigm shift by improving diagnostics disease classification and population implementation of early intervention in mm by detecting and treating mm at a precursor state hopefully leading to improved quality of life and potentially a cure the main objectives are to gather knowledge on the epidemiological clinical and patient reported outcomes of smm perform a unique nationwide early treatment trial and leverage this unparalleled collection of samples to make major new discoveries on the biology and evolution of smm
deconstruct stars revealing the enigmatic mixing process in the radiativeconvective boundary of stars using cuttingedge 3d numerical simulations

stars like our sun are complex systems in which hydrogen fusion occurs in the radiative core and heat is transported by convection in the outer part the two most important regions in sunlike stars are the optical surface and the transition region between the radiative core and the convective envelop called the tachocline the tachocline which is believed to be responsible for generating stellar global magnetic fields also related to the 11year solar cycle is a complicated region where the effect of rotation magnetic field diffusion of elements and convective overshoot interplays in this project we will carry out global convection simulations that range from radiative interior to the lower atmosphere for the sun and a few ftype stars using the stateoftheart dispatch code our ab initio simulations will include complex physical processes such as rotation and magnetic fields and are free from approximations typically adopted in previous works based on these simulations the applicant will quantitively study the problem of overshooting and gravity wave excitation near the tachocline which are crucial for a better understanding of the solar modeling problem the anomalous abundance of lithium in the sun and the cosmological lithium problem
kinesthetic displays creating embodied experiences of movement using vibrotactile feedback

kinesthesia awareness of position and movement of body parts is essential in all aspectsof life kinesthesia enables mundane activities such as typing or lifting a glass to our lips aswell as feats like playing a piano concert or competing in an elite sport it not only providesinformation about our body but also helps form an embodied understanding of the world aroundus although kinesthesia is central to human experience it is barely used in humancomputerinteraction hci however existing methods like visual retargeting or auditory body illusionssuggest that such displays are possible vibration exemplified by the pinocchio illusion mightbe an ideal actuation method to convey kinesthetic information however the literature showsno systematic way to achieve thisi aim to design kinesthetic displays kds general purpose devices that provide an embodiedexperience of movement i will apply a sensorimotor perspective to the design of vibrotactilefeedback building on my knowhow of using sensorimotor contingencies for designing vibrotactilematerial experiences in this project my team and i will design a series of prototype kds whichwill be used to study how design decisions stimulation parameters and algorithms influencethe introspective experience of movement the resulting data will be used to formulate designguidelines for kds and to establish an empirical theory of sensorimotor interactionkds will transform remote and colocated training and skill sharing kds will help us betterunderstand our own bodies and provide amputees with sensory access to prosthetic limbs orother body augmentations finally kds will provide digital systems with an embodied channelof communication revolutionizing how we interact with computers
industrial urban symbiosis and its social economic and environmental impact on different european regions

symsitess main objective is to implement regional industrial urban symbiosis in four european regions different in social economic and environment aspects from the north denmark through the mid austria to the south spain and greece the four ecosites will use the same technologies for wastewater and waste treatment and energy production and cycling enabling a clean comparison of the ecosite impacts the four ecosites will generate virtuous circles of energy treated waste and wastewater streams between urban and industrial entities the enabling technologies to be developed for waste and wastewater ww cotreatment are a newly developed it regional management platform itrmp including novel iiots and social decision support system sdss to manage efficiently the iu symbiosis an anaerobic bioreactoranmbr with advanced membrane coupled with a tertiary treatment to be installed at the four ecosites for a clean comparison of all impacts not directly influenced by different technologies the aim is a to achieve nearzero ghg emissions or co2 negative footprint b use of biowaste and nonrecyclable wastes nrw to produce energy and reusable water as well as highvalue new resources hvnr thus reducing the waste generation by 50 lca and lcc studies and the quantity prevented from transportation tonkilometer units and from landfilling tonm3 units will evaluate the costs and environmental impactdedicated tools will be developed to spread he ius concept within europe these include virtual demonstration of replication potential in other regions by setting up a network amongst waste associations facilitation services for implementing symbiotic processes actions to facilitate relations and to involve the local community actors and establishment of a social innovation non profit spinoff involving tools and business models for streams exchange in a dynamic production
injectable biomimetic octacalcium phosphate based composites with antibacterial action for implant reossteointegration

with increase of global dental implant industry perimplantitis became an emerging problem worldwide affecting up to 43 of the placed implants periimplantitis is caused by pathogenic microorganismsthat adhere to the implant surface triggering imflammation and bone destruction eventally leading to implant loss in half of the cases the overall aim of periimplantitis treatment is reosteointegration of implant with surrounding bone that can be achieved only in case of complete control over infection the existing treatment approaches are not able to provide efficient decontamination of the implant surfaces while effectiveness of the existing local antibiotic delivery systems is questionable the aim of this project is to develop biomimetic injectable capbased pastes with antibacterial and osteogenic properties for periimplantitis treatment we will utilize biocompatible materials such as octacalcium phosphate ocp and natural hydrogels hyaluronic acid and functionalized gelatin that closely resemble to the composition of inorganic and organic components of the bone extracellular matrix they will serve as versatile platforms for local delivery of antibiotics such as metronidazole and doxyciline or antimicrobial nanoparticles into the periimplant pockets after mechanical removal of the bacterial biofilm we hypothesize that these materials will offer control over infection in peri implant area and subsequent cellular functions and may have a great potential for implant reosteointegration to date antibacterial formulations of bone graft materials targeting periimplant oral microflora are not available in the market the obtained innovational products designed according to the principles of good manufacturing will have optimized composition and handling properties to be used straightforward at the chairside in dental office without additional invasive surgical manipulations
general relativistic numerical models of accretion disks and magnetic reconnection with the pluto code

magnetic fields shape the dynamics of relativistic plasmas that orbit around astrophysical black holes bhs as observed in current general relativistic magnetohydrodynamic grmhd models a primary example is magnetic reconnection ie the rearrangement of the structure of magnetic field lines which converts magnetic energy into kinetic and thermal energy and accelerates particles to relativistic velocities thus producing the highenergy nonthermal radiation observed from accreting compact objects despite the importance of smallscale instabilities in determining the properties of magnetic dissipation and particle acceleration global simulations of relativistic accretion disks usually consider either infinitely conducting fluid or one with a constant finite magnetic dissipation which doesnt capture the collisionless nature of astrophysical plasmas the goal of the grpluto project is to perform the first grmhd numerical study on reconnection in relativistic disks using an effective nonconstant resistivity which will go beyond standard fluid models by introducing new noncollisional effects in global grmhd simulations this approach will test our current knowledge of relativistic magnetic reconnection and provide more consistent estimates for the rate at which particles can be accelerated along with the general structure of magnetized accretion flows around bhs where this process occurs as the simulations required to quantify the improvements wrt stateoftheart relativistic mhd reconnection and grmhd accretion flow models have a high computational cost the action will include the development of a numerical tool for the modeling of grmhd flows based on the public pluto code in collaboration with the hosting group at unito the action will produce a new code that will combine the benefits of highly accurate numerical schemes with energyefficient hpc methods which will continue to be freely accessible by the public
timeresolved imaging of membrane transporter dynamics under physiological ionic gradients

without biological membranes there would be no life as we know it lipid bilayers shield cellular content from the environment creating defined micro environments with specific functionality transport of molecules and information across these membranes is carried out by integral membrane protein channels receptors pumps and transporters living cells maintain chemical gradients and electrical potential differences across their membranes the potential energy of which can be accessed by the membrane proteins to perform useful work indeed central processes such as metabolic energy generation and nerve impulse propagation directly depend on these membrane gradients due to their core role in the life of cells and in the health of living organisms such proteins represent the majority of all current drug targets therefore membrane proteins have been the focus of intense efforts to obtain highresolution macromolecular structure information however the current lack of experimental methods to carry out timeresolved structural studies of membrane proteins at physiological temperatures and under physiological gradients leaves a gigantic blind spot is our mechanistic understandingwe will address this challenge by bringing together our complementary expertise in membrane protein biology timeresolved structural studies photochemistry and nano fabrication methods we will link a set of stateoftheart technologies to build a technology platform based on a partitioned microfluidic liquid sample environment optimised for highresolution timeresolved structural studies of membrane proteins by serial electron diffraction from 2d crystals at room temperature and in the presence of physiologically meaningful membrane gradients for the first time this will allow us to structurally validate models based on biochemical and computational data and uncover new possibilities for modulation of function by small molecule therapeutics based on allosteric regulation