Dragon09/odtu_chatbot huggingface dataset:
accelerating circular biobased solutions integration in european rural areas

the main objective of biorural is to create a paneuropean rural bioeconomy network under which related stakeholders will cooperate to promote the currently available smallscale biobased solutions in rural areas to increase the share of bioeconomy giving increased value in such remote areas such framework will contribute in bridging the gap between the available novel highend biobased solutions and the everyday european rural life by assessing the existing situation of european rural bioeconomy capturing grassrootslevel needs and ideas promoting effective exchange of knowledge and information and investigating the possible opportunities for regional development through the expansion of biobased solutions integration in rural europe this way biorural will develop a transition framework towards a sustainable regenerative inclusive and just circular bioeconomy across all europe at local and regional scale and support innovators to scaleup inclusive and smallscale biobased solutions in rural areas to do so the project will i assess and evaluate the current performance of the european rural bioeconomy in the eu and identify factors affecting innovation adoption and diffusion of biobased solutions in rural areas ii create four regional rural bioeconomy platforms rbps that will form a european rural bioeconomy network erbn iii assess and promote success stories of biobased solutions in rural areas iv develop and continuously optimise an online open stakeholders tool named biorural toolkit v facilitate knowledge exchange and capacity building for the european rural bioeconomy through a series of workshops in local regional and european level vi create rural development blueprints for regional and business scaleup of resilient and circular biobased solutions in rural areas and vii disseminate and communicate all activities for maximum visibility and rural bioeconomy expansion
demonstrating large pit thermal energy storages and improving their components processes and procedures for an accelerated realisation of 100 sustainable district heating networks in europe

a fully decarbonised european energy system must be equipped with very large flexibility capacities enabling the uptake of intermittent renewable sources coupling energy sectors and increasing the energy system efficiency the treasure project paves the way for the accelerated realization of large pit thermal energy storages that serve as the enabler for fully renewable district heating networks and industrial heating systems with the project 7 demonstrators are being realized in 5 different countries the projects aim is to use synergies in order to improve cost effectiveness through the targeted development of improved components and the collective improvement of design and building processes monitoring data from an already operating storage and from the demonstrators are used for better numerical simulation of actual and future system performance through the participation of marketoriented partners possible solutions to the financing permitting and social challenges in the realisation of large pit thermal energy storage projects are mapped and discussed with the broad group of stakeholders with a core group of 15 satellite initiatives the experience with the operation maintenance and refurbishment of especially danish pit thermal storages is used to improve the design and operation of the demos the satellite initiatives and future storages in broad the project consortium is composed of partners from the complete value chain component suppliers building companies engineering companies research and developments institutes contractors energy service providers district heating companies and professional organizations the developed roadmap and generated knowledge in the fields of planning design components building system integration financing permitting and business plans is actively disseminated to experts and to decision makers in order to accelerate the realisation of more than 2000 large ptes needed for the full decarbonisation
one step open dbl solution

opendbl intends to integrate multidisciplinary knowhow to cover the requirements of the call and solve the issues of the current situation the challenge of the project is to allow through the development of openapi the disposal of opendbl in a unique standardized platform and create useful content to simplify the workload of the aeco industry the project pursues 3 objectives 1 create a dbl with useful content and functionalities 2 ensure opendbl is usable and simple to use reducing the time spent to upload search and process the information and data to facilitate usage and gain wide adoption 3 ensure attractive economics through value propositions and convenient pricing well provide any user with an integrated platform for their digitization needs ensure that information and data conform to the latest trends and needs of our target clients and support the eus circular economy and green policies develop automatic classification systems and data standards facilitate the operation and maintenance activities of the buildings this will be achieved creating an information delivery manual and a data model and further developing our existing platform used to create a dbl for an important italian public contracting authority opendbl will support data matching with external databases and will integrate state ofthe art technologies ai blockchain iot and vr our ambition is to make opendbl the platform of reference for the monitoring of building consumption transparencies of transactions and official documents and the positive impact on maintenance and environment
democratic literacy and humor

democratic literacy and humour deliah examines the multifaceted role of humour in artistic forms cultural spaces and online and offline fora identifying how humour can either support or undermine democratic participation and processes in europedeliah has two main goals1 to transform existing research on the adverse effects of antidemocratic speech which is particularly prevalent in humorous forms in online platforms into actionable policies toolkits and educational resources to mitigate the negative consequences of such antidemocratic speech such practical approaches will in turn enhance what we call democratic literacy ie the capacity among eu citizens and regulators to discern the antidemocratic implications of certain forms of hateful speech or disparaging humour 2 to conduct fundamental research into humorous counterspeech which will allow deliah to develop and promote humour strategies that confront antidemocratic rhetoric hate speech and discriminatory content thus establishing best practices for using humour as a tool to counteract antidemocratic speech and thereby foster broader and more meaningful participation in democratic processesdeliah therefore recognizes humours dual potential first deliah investigates how humour can be misused to support antidemocratic agendas and in response offers strategies to boost awareness regulate content and mitigate harm second and simultaneously deliah harnesses humours positive role in countering such rhetoric advocating for practices that encourage active and healthy democratic engagement in sum deliah is dedicated to exploring and establishing the delicate balance between humours potential to harm and its capacity to heal in a democratic context aiming to cultivate a more informed resilient and participatory democratic society in europe
encode unveiling emotional dimensions of politics to foster european democracy

despite emotions being a driver of political choices building democratically meaningful emotional narratives in politics remains an uncharted territory hence the main venture of encode is to decode the meanings of emotions and encode them to policymaking strategies aiming for a positive emotional turn breaking the cycle of depolarisation to meet this ambitious goal encode builds its conceptual frameworks arising from a novel concept of affective pluralisation as opposed to affective polarisation this term serves to frame empirical research carried out in 6 geographically diverse european countries representing both eu member states and candidates this study will span desk research sentiment analysis biometric research indepth interviews experiments and panel survey such triangulation of research techniques ensures the accuracy and validity of the findings these are further encoded into main outputs catalogue of best practice to tackle disinformation in social media emotional gap maps validated survey questions and democratic resilience heatmaps these outputs are not expected only to enhance current scientific framework but also are planned to underpin the future emotional narratives codesigned by diverse groups of citizens in innovations labs and further validated by delphi expert panels and vignette experiments this bottomup approach anchored in citizen science ensures that policymaking strategy are in first place created by citizens and only in the next step discussed by expert teams who will elaborate policymaking strategies the roadmap for their implementation alongside future foresight scenarios which will be disseminated widely across eu and eu wide community of 1000 members this strategy creates emotional bonds between ordinary citizens increases trust in governance and supports better informed political decisionmaking and communication
innovative in situ 4d bioprinting for regeneration of colorectal mucosa and submucosa

colorectal diseases are a cohort of pathologies that affect the mucosa and submucosa layers of the anus rectum and colon of more than 2 million individual in the eu among them familiar adenomatous polyposis fap and ulcerative colitis uc seriously compromise the patients quality of life these pathologies could benefit from the removal of the intestinal mucosa and submucosa however no strategies exist nowadays for their replacement then when their removal is necessary the patients undergo a proctocolectomy ie surgical removal of the rectum and all or part of the colon with a subsequent ileal pouch although preserving the patients continence the procedure is burdened by significant complicationsin this scenario tentacle pioneers a radically new strategy for the surgical treatment of uc and fap providing an innovative in situ 4d bioprinting strategy for the regeneration of colorectal mucosa and submucosa the tentacle in situ 4d bioprinting suite include i a colonoscopic bioprinter featuring an extrusionbased bioprinting unit an valvejet printhead a mesh delivery system and a photocrosslinking device ii in silico tools for personalizing the bioprinting procedure iii two novel bespoken bioink formulations containing patients cells including suitable functionalization strategies the mucosal formulation will feature a 4d shape morphing behavior to recreate the colorectal mucosal crypts within tentacle the entire procedure will be validated ex vivo and in vivo thus paving the way for translating the bioprinting suite toward the clinics by i identifying a gmpcompliant cell expansion protocol ii scaling up of the manufacturing routes iii promoting involvement and acceptance of surgeons and patients iv aligning with the eu regulation collectively our project will introduce a minimally invasive alternative to proctocolectomy and is expected to have a high impact on the quality of life of patients affected by fap and uc
breaking the penetration limit of microscopy photoswitching optoacoustics

swopt is a novel imaging technology that will break through the penetration limits of optical microscopy to visualize individual cells and their function in vivo through several millimeters to centimeters of depth swopt will exploit 1 optoacoustic imaging oai a modality which combines signal generation similar to optical imaging with the wholeanimal imaging capability of ultrasound readout and uniquely augment it with 2 photoswitching to resolve signals from single labeled cells from deep within live tissue this will achieve volume sampling abilities surpassing any optical microscopy by at least three orders of magnitude 5 x 5 x 5 mm imaging volume swopt will develop the necessary breakthrough instrumentation and concepts unique multiplexed diode illumination novel ultrawideband transducer technology dedicated inversion algorithms that incorporate photoswitching in the threedimensional reconstructions and uniquely tailored classes of photoswitching transgene and synthetic molecular tools the exceptional capabilities of swopt will be demonstrated by proofofconcept work resolving cellular dynamics and functions in a whole tumor in a model of renal cancer in vivo swopt builds on the worldleading expertise in the disciplines of oa imaging technology ntziachristos ger applied mathematics unser ch and cancer metabolism frezza uk and is driven by excellent young researchers in proteinengineering stiel ger and chemical synthesis szymanski nl and supported by the sciencetotechnology focus of ambitious hightech smes sonaxis fra ithera ger swopts uniquely comprehensive yet detailed imaging will enable examination of whole tissues in vivo with the same ease flexibility and eventually abundance of tools paralleling fluorescence microscopy thus bringing research and understanding of living organisms to the next level as an affordable imaging technology swopt aspires to become routine in life science and biomedical research
entangled christianities in jerusalem and the middle east a crosscultural bottomup approach 12th16th centuries

chriscross will produce the first comprehensive study of christianities in jerusalem and the middle east from the 12th to the 16th c in the face of shifting rulership structures first frankish then islamic and religious affiliations it will envisage them from a bottomup practice oriented and connected perspective on the assumption that interchristian and christianmuslim relations were more conductive to fluidity than to boundarysetting a multidisciplinary and multilingual team will study a forgotten and so far inaccessible archivethe archives of the christian patriarchates in jerusalemand develop an overarching database including interactive maps and editing texts openaccess metadata will be in english and arabic in so doing it will resituate the history of christianities within the islamicate world by reassessing the concept of minority historicise communities construction by comparing conquestinduced reconfigurations with and without a change in religious dominance and spatialise these processes by examining their interplay with jerusalem as a specific urban space in tension with the wider regional areathe project has three main objectives it aims to address the currently compartmentalised academic study of the diverse frankish and islamicruled societies by shifting the focus of inquiry from the internal history of separate groups to their areas of contact to empower local christian communities by documenting their deeprootedness in these complex societies and to contribute new knowledge of the diversity of the islamicruled world as a historical reality by expanding digital inclusiveness by achieving its various objectives chriscross will realize what arguably is an unprecedented exploration it will thus have a major scholarly and social impact both for the many christian communities now facing extinction and for people in the socalled west which faces an inflation in essentialist discourses on religion
novel wefe nexusbased approaches towards agroforestry management in the greater north african region

transsahara will establish a groundbreaking approach for leveraging agroforestry systems to support african communities in their fight against climate change this innovative approach is based on the wellestablished waterenergyfoodecosystems wefe nexus approach which emphasizes the primacy of ensuring water security when designing installing and managing agroforestry systems the translation of this conceptual agroforestry management approach into realworld applications is supported by an array of technical and nontechnical innovations these include cuttingedge measurement methods and tools to accurately assess environmental and socioeconomic impacts scalable naturebased intervention strategies to facilitate sustainable exploitation of natural resources and novel business models designed to secure longterm livelihoods of local communities engaged in agroforestry practices the efficacy of the novel approach and supporting innovations will be rigorously tested and validated through a series of largescale pilot demonstrations set to take place in key locations across africa including tunisia ghana and ethiopia novel communityled engagement methods are used to support the codesign of the demonstrators and ensure deep acceptance of the innovation within local communities expected outcomes will contribute to bridging the agroforestry data gaps in africa increased crop yield doubling of farmers annual incomes and creation of new carbon sinks across previously degraded territories an ambitious postproject exploitation plan executed in partnership with eu and african policymakers and civil society groups foresees the immediate and widespread uptake of resulting innovations across african union au member countries and beyond by 2030 innovation adopters will significantly enhance their communities resilience to threats posed by the climate emergency and stimulate highly sustainable socioeconomic development across their region
endothelial immunosuppressive mystery genes for alternative immunotherapy artificial intelligencedriven target discovery and lipid nanoparticlernabased target validation

compared to my previous advanced erc grants this proposal is fundamentally different not only concerning its topic but also regarding its ambition to offer greater societal impact by coupling knowledge gain tighter to translation it promises to obtain new insights in an understudied endothelial cell ec subtype with immunomodulatory gene signatures coined imecs highly relevant for alternative immunotherapy development indeed silencing immunosuppressive genes in imecs offers unprecedented opportunities to improve the efficacy of and to overcome the resistance to current anticancer immunotherapy to which the immunosuppressive tumor endothelium contributes to identify previously unknownunmined virgin drug targets we also focus on mystery genes lacking functional annotation pubmed reports comprising 30 of the human coding genome we developed i an innovative artificial intelligence aibased tool scmysterydentifier to predict new immunosuppressive functions for endothelial mystery genes and ii a revolutionizing revolt technology based on injecting ecselective lipid nanoparticles containing sgrna in mice expressing cas9 selectively in ecs to generate ecspecific knockout mice rapidly daysinexpensively 300mouse at an unprecedented scale in order to validate these targets demystifying the mystery genome offers formidable opportunities for knowledge gain and therapy development we will validate 50 new ec targets and aspire to identify and patent 5 previously unknown targets for alternative imecbased immunotherapy the scmysterydentifier tool can be made generic to discover any type of function for mystery genes in any cell type while the revolt technology promises to revolutionize the pace of genetic research in the vascular biology field offering formidable impact for the research community in academia and pharma
multimodal engagement and sustainable lifestyle interventions optimizing breast cancer risk reduction supported by artificial intelligence

meliora consortium will jointly work with local actors at different levels for the realization of eight 8 in total tailormade lifestyle intervention and behavioural modification studies including artificial intelligence and digital tools to promote sustainable behavioural changes among three target populations i healthy women at risk of developing breast cancer ii breast cancer patients and iii breast cancer survivors the studies will take place across 4 different european countries greece sweden spain and lithuania and 6 piloting centres targeting 2000 women in urban and rural areas including participants throughout the socioeconomic spectrum primary health care centres hospitals or patientssurvivors organisations will be used as entry points to the community the goal of the meliora virtual coach interventions is to evaluate its effectiveness through assessing the effect of multiple individual and contextual factors to the uptake and sustainability of behavioural changes at the same time identification of specific bottlenecks and barriers that prevent the uptake of sustainable behavioural change will support the development of approaches on how to best reach and involve disadvantaged socioeconomic population groups vulnerable groups and people living in rural areas and will provide best practices for behavioural intervention uptake and scaleup regular monitoring will be ongoing during the implementation to allow corrective actions and ensure effective adaptation and uptake based on the study outcomes the health economic evaluation and budget impact analysis and data deriving from the scalability assessment national and european stakeholders will be invited to evaluate through workshops the potential for adoption of the meliora virtual coach interventions in other regions or countries in europethis action is part of the cancer mission cluster of projects on prevention early detection behavioural change
coherent comb for copackaged optics

the volume of data produced managed and consumed continues to grow exponentially driven by emerging technologies like machine learning artificial intelligence and blockchain demand for compute power to support these services is growing at 10x every 18 months and datacenter operators are struggling to keep up significant challenges have emerged in datacentre networks around bandwidth signal integrity power and faceplate densitythe migration of the optical interconnect to the board copackaged optics cpo and to the chip optical io oio has been proposed as a potential solution however only a few years into this new paradigm two of the available dimensions for system scaling fiber and wavelength count are already heavily utilised posing scaling challenges in the near term todays cpooio systems use intensity modulationdirect detection but given these pressures a transition to coherent is inevitable cocopop will deliver the first coherentcapable external laser source els which benefits todays systems and also futureproofs them by enabling full exploitation of the third scaling dimensionbit ratewavelengththrough coherent communication in doing so pilot photonics will capture for europe a key position in this strategically important market segment forecasted to grow to 22bn by 2032building upon developments in eic picomb the chipscale frequency comb that will be matured and commercialised through cocopop brings many benefits over commercial state of the art dfb arrays such as unmatched linewidth relative intensity noise output power and wavelength stability derived from the synchronisation and locking of independent lasers with a low linewidth frequencylocked optical frequency comb ofcpilot has a proven track record in commercially exploiting the outcomes of advanced rd programmes in the area of chipscale ofc technology and we intend for the cocopop els to be on the market within two years of cocopop project end