Dragon09/odtu_chatbot huggingface dataset:
hybrid nanoporous materials for the separation of fluid mixtures

nanoporous solids in interaction with fluids are ubiquitous in our environment benefiting from a large specific surface area nanoporous materials interact strongly with fluids which makes them an excellent choice for fluid separation applications but for new applications to emerge a deeper understanding of the behavior of confined fluid mixtures within multiscale porous materials is required which is made difficult by the rich behavior of nanoconfined fluids and the geometric and chemical heterogeneities displayed by most porous materials the objective of this proposal is to understand how the behaviors of fluid mixtures confined within heterogeneous porous materials impact largescale fluid demixing properties and how can this knowledge be used for designing efficient nanoporous filters to do so i will setup a multiscale numerical procedure that extrapolates molecular simulation results to the macroscale through a twostep bottomup approach the two fluid mixtures co2n2 and ch4n2 have been chosen for their high environmental and industrial relevance this bottomup investigation will allow for the exploration of the equilibrium and transport properties of the confined fluid mixtures for a large range of surface and geometrical properties of the nanoporous material and address the issue of transport and demixing of fluids in heterogeneous porous materials this investigation will also help foresee the potential of hybrid porous organosilica for the separation of co2n2 and ch4n2 mixtures
ascent to the kingdom the eucharistic ethics of maximos confessor

the main thesis of my postdoctoral project entitled ascent to the kingdom the eucharistic ethics of maximos confessor is that maximos subscribes to a kind of eucharistic ethics in which the human is called to offer back the gift of being in the form of gratitude eucharistia culminating in the perfection of being the unificatory state of deification i argue that maximos ethics is fundamentally an ethics of oneness of the progressive realization on a personal and cosmic level of the fundamental unity at the heart of reality this unitary ethics is summed up in the inseparability of virtue contemplation together these practices work to overcome the inner fragmentation of the self and the outer divisions of the world introduced by ignorance and sin all the virtues be it humility forbearance detachment charity love fasting contemplative prayer vigils worship represent means of overcoming the instability of a life centred upon the finite self the ego leading to a more grounded godcentred life the ethical life in essence represents the overcoming of divisions and the progressive reunification of self and world culminating in union with christ and the trihypostatic god who alone is one the inherently unificatory practice of the virtues as manifold expressions of love is corroborated by contemplative insight into the oneness of god nature and the human person virtue and contemplation culminate in the unity of divinehuman love agap
nest ingrained ecosystem for zero emission buildings

reduction of embodied emissions is crucial for achieving sustainable and lowcarbon building practices greenest creates an ecosystem that integrates co2 neutral building materials reused recycled and locally sourced biogenic materials and renewable energy sources abiotic components into the building design together with human response and naturalgreen systems biotic components to demonstrate resource efficient construction that needs less materials and implements energyefficient circular construction practices the project targets 100 carbon free construction through the application of biogenic materials that store carbon the reduction of embodied emissions by 50 with respect to nzeb standard zeb or even positive energy standards via renewable energy sources with remaining primary energy consumption less than 3040 kwhm2 reduction of ghg emissions by 60 and increased productivity of construction by 30greenest delivers a palette of innovative solutions for new buildings addressing all stages of the buildings life from the design stage up to the end of the buildings lifetime and disposal stages including reuse and recycling of components it proposes sustainable envelope components based on low carbon and carbonneutral market mature materials using onsite renewable energy reducing waste enhancing productivity of construction through digitization and demonstrating circular economy principles the innovative solutions will be fully demonstrated in four real and two virtual new construction projects in five countries using local and regional value chains increasing the potential for replication across europe the greenest consortium benefits from a strong industrial and commercial involvement with 11 smes 1 large company 3 universities 3 associations and 2 public bodies from 8 european countries
incell redox catalysis by coiii metallodrugs as new tools for cancer treatments

the search of new therapies for cancer is a primary eu mission incell redox catalysis promoted by organometallic complexes of precious metals as ruii osii rhiii and iriii is a novel promising concept to access more efficient safer and less invasive medicines cocared aims to design new incell catalytic systems based on halfsandwich coiii complexes cobalt combines effective catalytic performances for biomedical applications and high catalytic versatility moreover it is a cheap sustainable and biocompatible metal whose peculiar chemical properties can access unique reactivity pathways the project will focus on the development of new synthetic catalysts on their applications in redox reactions of therapeutic interest involving known examples and unprecedent cases of study and on the unveiling of their biological mechanism of action in cancer cells cocared will be implemented in a vibrant and stimulating research environment at imdea nanociencia in dr ana pizarro research group the project will benefit of the complementary expertise of the er in organometallic chemistry and redox catalysis and of the supervisor in studying the intracellular reactivity at the molecular level of metalbased drugs an intense training plan is designed to equip the researcher with the necessary skills to study the biological activity of the coiii catalysts including singlecell studies and to design proofofconcept experiments that confirm the occurrence of a metalbased catalytic reactivity inside the human cellsthe main goal of cocared is to generate novel redox catalytic systems based on more biocompatible less toxic and cheaper cobalt drug candidates as complementary tools to noble metal complexes
augmented social play asp smartphoneenabled group psychotherapeutic interventions that boost adolescent mental health by supporting realworld connection and sense of belonging

in our fastchanging society poor mental health and social isolation are increasing among young people exacerbated by the pandemic belonging feeling connected to and accepted by others through supportive interpersonal relationships is key to boosting mental health and overcoming loneliness there is a lack of evidencebased interventions addressing belonging particularly in schools which remains a central space for adolescent socialisation digital technologies while disrupting the social landscape offer enormous potential for adolescent health management this project develops augmented social play asp a pioneering digital mental health intervention format whose feasibility has been established through proofofconcept prototype asp uses smartphones to deliver realworld group experiences that combine immersive storytelling augmented reality collaborative facetoface gameplay and evidencebased psychotherapeutic methodologies to boost individuals mental health while fostering a greater sense of belonging within the group collaborating across academia industry education health and the arts and working with young people we will codevelop asp 1 a fullscale multisession intervention we will implement this intervention in schools in portugal czechia and the uk using strategies informed by policy review and evaluate its efficacy costeffectiveness and implementation in order to present an evidence base to stakeholders including policymakers practitioners and media stimulating wide uptake we will further evolve asp by collaborating with vulnerable adolescents to ensure we meet the widest spectrum of needs
securing domestic production of costeffective biomethane

semprebio aims to demonstrate novel and costeffective biomethane production solutions and pathways deemed essential to achieve the european green deal and climate and energy targets for 2030 and the net zero greenhouse gas emissions by 2050 and to increase the market uptake of biomethane related technologies to that extent semprebio will set up three european biomethane innovation ecosystems ebies based in baix llobregat es bourges fr and adinkerke be which are representative of the different baseline situations for biomethane production across europethose initial ebies will facilitate longterm replication by creating an active flow of information and resources for ideas to transform into reality through the ebies semprebio will build a process by which more innovators and entrepreneurs will be able develop and launch solutions to solve problems related to the largerscale and cheaper production of biomethane faster this process will create new technical expertise helping to diversify the technology portfolio and will allows businesses to better know their potential customers additionally ebies will provide the means to create economic stability and resource sharingthe value of ebies lies in the access to resources for the startups and the flow of information for the ecosystems stakeholders this information flow will create more future investment opportunities for the right institutions to connect with the right ideas for their businesses and portfolios at the right time for the right reasonsoverall the challenge is to decrease investment and operational costs to optimize feedstock supply use identify alternative feedstock as well as reduce their costs to improve plant efficiency and operations to factor in the carbon savings and to increase and monetize cobenefits such as from the commercialization of the digestate or the valorization of residual gas streams
building innovation procurement capabilities in big science

innovation procurement is a largely underused mechanism in the publicly funded big science organisations bsos such as cern ch euxfel de european spallation source esssweden fusion4energyf4eiter bsos represent huge european public investments estimated at 387 bn for the coming years bsos are recognized as drivers for innovation with a huge impact on society in fields such as energy health materials environment and it inprocap will establish codesigned innovative procurement practices in bsos through inprocap a fragmented network of industrial liaison offices ilos will be able to provide advisory services and involve their huge network of national and international smes and deep connections to the innovation ecosystem more than 200 companies will be engaged in innovative procurement for bsos through inprocap the inprocap consortium is uniquely positioned to potentiate innovation procurement opportunities for bsos by involving four ilo networks dtidk nwonl cdties ncbjpl covering the entire european region the ilos will cocreate and receive training on innovation procurement developed with and provided by an sme with vast experience in innovation procurement pedalsk inprocap partners will engage their wider network of startups and innovative companies while ensuring that bsos are capable and prepared to embark on innovation procurement processes bsos are directly involved in inprocap through euxfelde and eiscatse who will identify their innovation procurement needs that will be presented to smes for codesign through inprocap innovation procurement will become a standard tool in the bso toolbox the potential of smes to increase their supply of innovations to the public sector bsos will be widely disseminated and the innovation procurement cases developed in inprocap will serve as examples for bsos across the world contributing to overcome the current dispersion observed in innovation procurement
xrayinduced fluidization a nonequilibrium pathway to reach glasses at the extremes of their stability range

i will address the fundamental question of what exactly are and how to prepare glasses at the extremes of their stability range ultrastable ideal glasses on the one side and ultraunstable defectsaturated glasses on the opposite side the ideal glass predicted by some theories of the glasstransition but not yet observed is a novel equilibrium state of matter characterized by a fairly unique dense atomic structure with almost no defects the defectsaturated glass is instead ductile at odds with conventional glasses any additional defect selfheals i will reach these extraordinary states employing a nonthermal fluidization route activated by xray irradiation its nonequilibrium nature is key here conventional thermal treatments that induce structural changes stabilized by quenching modify the properties of glasses only over a limited range my project aims then at1 producing ideal and defectsaturated glasses2 developing a general scheme to control the stability of glasses3 establishing experimentally the connection between their thermodynamic properties and their density of defects4 clarifying the microscopic mechanism of xray induced fluidization5 describing the glassspecificity of this effect in terms of amorphous plasticitythe importance of these extreme glasses is however not only fundamental the reduced zero density of defects makes the ideal glass mechanically and optically lossfree a defectsaturated glass instead deforms under load and crystallizes very rapidly their properties are therefore enabling for new technological applications ranging from noisefree mechanical resonators superconducting qubits with sufficient coherence for quantum computers and phasechange materials for applications as memoriesthe longterm vision is that the knowledge of how to measure and control the density of defects in glasses will lead to materials with extraordinary properties of relevance for many important applications
advancing orbitronics by pushing electron orbital angular momentum to terahertz speed

the spin angular momentum s of the electron has significantly extended conventional electronics which relies on the electron charge c by new socalled spintronic functionalities examples include magnetization switching the transport of s and its detection even down to femtosecond time scales to boost the efficiency of spintronics the so far neglected yet equally fascinating and important orbital angular momentum l of electrons is considered to be a powerful pathway orbitronic phenomena such as lbased transport torques and magnetooptic effects have much larger magnitude than their s counterparts and may thus efficiently complement or even replace spintronic functionalities microscopically l is completely different from s its dynamics involves new physics that needs to be understood in particular on ultrafast time scalesin the orbitera project my team and i will obtain unprecedented insights into l dynamics by using femtosecond optical pulses and terahertz thz electric fields which couple directly to the motion of conduction electrons at their natural frequencies and relaxation rates we will tackle important challenges of general orbitronics and in particular separate l and sbased effects despite their identical macroscopic symmetry properties build ultrafast generators and detectors of exclusively l currents reveal the nature of l transport eg ballistic diffusive tunneling measure the magnetic moments forming an l current probe the interaction of l with the crystal lattice temporally resolve ls and lc interconversion and apply thz l torque to ultimately switch magnetic order ultrafastby establishing thz orbitronics new methodology such as ultrafast drivers of l currents and lconductance spectroscopy at 0150 thz and applications such as the detection of thz electric fields without relying on the weak spinorbit coupling will be developed that can be used by a community beyond specialized thz labs
highquality datadriven services for a digital built environment towards a climateneutral building stock

traditional silo approaches where stakeholders manage their own data could be replaced by digital and smart buildings merging heterogeneous data sources and placing the stakeholders as the core of these buildings digibuild will catalyse this muchneeded transformation by making use of highquality data and next generation digital building services supporting the deployment of euwide framework for a digital building logbookan inclusive environment for multistakeholder knowledge exchange based on european bauhaus initiative will be applied to codesign enduseroriented services digibuild will provide an open interoperable and cloudbased toolbox to transform current silo buildings into digital interoperable and smarter ones based on consistent and reliable data supporting betterinformed decisionmaking for performance monitoring assessment planning of building infrastructure policy making and derisking investments it will be built on top of existing platforms and common eu initiatives towards an energy efficient building data space based on standard clouddata platform frameworks fiware and data space initiatives gaiax and idsa on top of this advanced data governance framework we will create aibased data analytics and digital building twins based on highquality data aiming to facilitate transparency trust informed decisionmaking and information sharing within the built environment and construction sector which will be deployed across 10 realworld conditions trl 8 digibuild will contribute to the uptake of digital technologies in the building sector to better align the eu member states longterm renovation strategies with the epbd requirements on decarbonisation and on a path towards a climateneutral building stock by 2050
a novel role for skeletal muscle in tumour growth and proliferation

cachexia is a lifethreatening condition characterized by a drastic loss in both muscle and adipose tissue which is associated with several pathologies including cancer in cancer patients its prevalence is of 5080 and is the direct cause of at least 20 of cancerassociated deaths cachectic patients show lower response rates to chemotherapy and a reduced tolerance to anticancer treatment being of major clinical relevance so while cachexia is clearly of great significance for disease prognosis and survival in general it is mainly considered a consequence of the presence of the tumour tumourinduced muscle wasting is due to the development of anabolic resistance which is the impaired ability of nutrition and exercise to stimulate muscle protein synthesis there have been results however which suggest that prevention or reverting muscle mass can lead to significant improvements of survival and overall wellbeing of tumourbearing animals while these results are suggestive of an important role for skeletal muscle whether or not this is due to a direct effect on tumour biology is not wellestablished the proposed project is based on preliminary results showing that tumour growth and proliferation are affected by activating the anabolic kinase akt specifically in skeletal muscle in vivo suggestive of muscletumour crosstalk follow up experiments performed using a microfluidics system showed that this effect is likely mediated by factors directly released by skeletal muscles and not through indirect effects like altering food intake or modulation of the immune system in the current project we propose to confirm and further decipher the muscletumour crosstalk in vivo subsequently we propose to identify musclesecreted factors with a microfluidics approach analyzing their effect on multiple tumour cell lines
utilization of marginal lands for growing sustainable industrial crops and developing innovative biobased products

midas aims to develop evaluate and optimize sustainable lowiluc feedstock by developing selected industrial crops and cropping systems on european marginal agricultural land in a climateresilient and biodiversityfriendly way to support feasible biobased value chains mapping of the actual and future marginal lands that may be certified as lowiluc including current and future expectations on soil erosion and water stress as well as biodiversity challenges and potentials ecosystem services and guidelines for enhancing cobenefits will improve understanding of the available marginal land for lowiluc biomass production selected industrial crops already adapted to marginal lands will be optimized through modern biotechnology tools particularly for wateruse efficiency and through tailored agronomic practices towards improved resource efficiency case studies of innovative farming systems intercropping agroforestry established on marginal land at farm level will improve harvesting solutions biodiversity data and guidelines while relevant actors farming community biobased industry academia will be engaged through regional advisory groups from the produced biomass innovative biobased products biochemicals composites and elastomers will be developed following the biorefinery and the circular use concept potential biomasstoproducts pathways will be identified leading to value chain web concepts that will be assessed for sustainability and will produce a multicriteria tool for the design of sustainable biobased value webs while enhancing regional biodiversity finally business plans to foster circularity at farm level by engaging the farming community industrial actors and academia through the projects case studies will be developed moreover through international cooperation brazil canada on crops cropping systems and bio based products midas allows best practices exchange and contributes to winwin scenarios development
into the blue resolving past arctic greenhouse climate

the arctic ocean is turning blue abrupt arctic warming and amplification is driving rapid sea ice decline and irreversible deglaciation of greenland the already emerging substantial consequences for the planet and society are intensifying and yet modelbased projections lack validatory consensus to date we cannot anticipate how a blue arctic responds to and will amplify an increasingly warmer future climate nor how it will impact the wider planet and society climate projections are inconclusive as we critically lack key arctic geological archives that preserve the answers this arctic challenge of global significance can only be addressed by investigating processes consequences and impact of past greenhouse warmer than present states the timeliness of i2b is tied into retrieval of revolutionary new arctic geological archives of past warmth and key breakthroughs in climate model performance that will be integrated in a concerted framework beyond stateoftheart i2b will deliver a groundbreaking synergistic framework to answer the central question why and what were the global ramifications of a blue icefree arctic during past warmerthanpresentclimates this will be addressed through three connected crossdisciplinary objectives integrating the expertise knowledge and skillsets of three pis and their different arctic paleoclimate and modelling teams i2b will quantify cryosphere sea ice land ice change in a warmer world o1 that will form the scientific basis for understanding the dynamics of arctic cryosphere and ocean changes o2 to enable quantitative assessment of the impact of arctic change on ocean biosphere climate extremes and society o3 that will underpin future cryosphereinclusive ipcc assessments i2b will solve the arctic challenge with the synergistic multiplier of the 3 pis expert capabilities providing pioneering knowledge on how a blue arctic impacts earths climate during greenhouse climate states