Dragon09/odtu_chatbot huggingface dataset:
microwave fingerprinting artificial molecular motors in virtual isolation

microartis is the blueprint for a fiveyear program of frontier research to develop a sophisticated spectroscopic approach to study artificial molecular motors the ultimate goal will be to demonstrate the harnessing of conformational dynamics of molecular motors in the gas phase using microwave spectroscopy my recent research has shown we can measure broadband microwave spectra of molecular motors in idle mode such achievement was remarkable not only because rotationally resolved studies of molecules of this size were out of reach until now but also because it opens a gateway to a new research line that is risky and ambitious but its potential is clear emerging from a static frame to studies of molecular motors in action in the gas phase will unlock their structural dynamics with unprecedented control over the environment molecular nanotechnology will gain a new experimental tool that is highly compatible with theoretical modelling approaches the significance of this project emerges from the current lack of highresolution probes that are able to capture a complete structural picture of the mechanical steps of these architectures an evolved structuresolving tool will be developed exploiting the unrivalled abilities of microwave spectroscopy to recover threedimensional structures from rotationally resolved spectra the virtual isolation created in gas phase molecular ensembles will be exploited to disclose intrinsic and interfacial structural manoeuvres of molecular motors for the first time rotationally resolved studies of molecular motors will be carried out in gearedmode and in the gas phase a new technology for thermal and optical control of samples will be developed to augment the molecular library at reach carving a path for this methodology to extend beyond the fiveyear lifetime of the project a new vision for spectroscopy of artificial molecular machinery will emerge and significantly advance this frontier of research
a precise and versatile nanotechnology with seed biostimulant microbial molecules to potentiate crop growth and immunization

seed germination is the first step of a sequence of events that promote the transit of seeds from dormancy to vegetative growth therefore it is a tightly regulated program that ensures further plant growth and survival in a supportive environment the emergency provoked by continuous deterioration of the environment due to nonrespectful crop management strategies and potentiated with climate change has increased the focus on this primordial stage of the plant growth as a primary target of strategies that help mitigating unsustainable issues beneficial microbes live in association with all plants and we know how to take advantage of this benefit for the wealth of adult plants however little is known on their contribution to seed resilience and adaptation to a changing environment this lack of knowledge may lead to unfeasible and weak biostimulant results undermining their credibility and entry into the market supported by findings of our deep investigation on the mutualistic interaction microbeseed we propose a proof of concept for a precise and customizable strategy based on the use of fengycin a molecule produced by bacillus cells in the interaction with seeds and a finetuned nanotechnology platform to improve and increase the mobilization of nutrients of oil bodies containing seeds we do expect a better adaptation of plantlets to the environment major adult plant growth and immunization against microbial pathogens and an average 50 reduction in the use of fertilizers and pesticides altogether our methodology should serve to improve the credibility of biological solutions as potent biostimulant of seed growth and thus potentiate their inclusion in sustainable programs of crop production and protection
drivers of spatiotemporal variation in temperaturerelated morbidity and mortality in europe analysing early adaptation to climate change

europe emerges as a major climate warming hotspot the temperature rise in the region has occurred at a rate faster than any other continent in recent decades with 2020 being the warmest year on record at more than 16c above the period between 1981 and 2010 such a change in temperature has serious implications for health wellbeing and quality of life of the european populations as warmer conditions are expected to contribute to an increase decrease in heatrelated coldrelated burden of disease morbidity and mortality however there is still insufficient understanding of the impacts of climate change on human health throughout the european union particularly at local level and this gap in knowledge continues to hinder adaptation efforts of the local and regional authorities lra the purpose of tempmomo is to assess the recent evolution in morbidity and mortality risk and burden associated with ambient temperatures and its main demographic and socioeconomic drivers in france and spain using a multiscale spatial analysis approach towards this aim tempmomo will generate a massive database with daily counts of death and hospital admissions together with the best available climate demographic and socioeconomic datasets the project will greatly contribute to the eu mission on adaptation to climate change by addressing knowledge gaps and providing customised data and tools that help decision makers to take informed decisions at all levels of governance from local to country level to protect human health specifically by the end of the project all the local administrative units lau and regions nuts in france and spain will have easy access to data and climate risk profiles through an interactive mapping tool the temperature and health vulnerability atlas to better prepare for climate change related shocks and disruptions
textilebased wearable soft robotics with integrated sensing actuating and self powering properties

wearable soft robotic devices for rehabilitation and motion assistance have emerged in the past decade as promising robotic systems owing to their adaptable morphologies soft robotics allow safer humanrobot interactions as opposed to rigid exoskeletons made of metals elastomers and textiles have become attractive lowcost and flexible material solutions to build wearable soft robots despite their high potential the demonstrated solutions of previous studies are bulky unreliable nonscalable and have limited portability and mobility all those drawbacks do not allow practical applications of soft robotic devices for at home assistance and rehabilitation during activities of daily living where they are intended and most needed the core objective of texwearots is to develop untethered knitted soft robotic assistive devices to overcome current drawbacks related to the wearable softrobotic system reliability mobility sustainability and integration texwearots focuses on the development of a knitted robotic glove free from bulky components with seamlessly integrated actuation sensing and selfpowering functionalities with my solid experience in textile manufacturing soft sensors and soft robotics i will leverage the latest advances in digital machine knitting to manufacture 3d actuator shells with the integrated functionalities in a monolithic manner this will lead to garmentlike customizable textilebased robotic devices which are highly scalable and reliable furthermore i will enable thermally powered fluidic actuation mechanism through integration of soft peltier cooling functionality which enhances the actuator response time needed for motion assistance applications texwearots combines textile and material science physiotherapy robotics electronics and biomedical engineering the proposed novel technologies and manufacturing techniques of the glove will lead to a breakthrough in wearable soft robotics and wearable electronics at wide
respiratory hostpathogen interaction

lower respiratory tract infections resulting from seasonal epidemics and pandemics are among the leading causes of death globally there is a paucity of treatment options for viral respiratory pathogens and patient care remains largely supportive this underscores a desperate need for identifying novel targets for prophylactictreatment interventions and early prediction models of disease outcome to personalise treatment the react consortium uniting highlevel experts in virology immunology clinical medicine epidemiology and bioinformatics will assess genotypic highdimensional immunophenotypic demographic and clinical data in the context of disease course to define hostpathogen interactions of viral respiratory tract infections focusing on the predominating viruses ie influenza respiratory syncytial virus rsv and severe acute respiratory syndrome coronavirus 2 sarscov2 in characterised ethnically diverse clinical cohorts comprising patients with varying disease severities we will genotype both virus and host map deep immunological phenotypes spanning cellular humoral and innate immunity and characterise host responses in human nasal epithelial organoid models following viral infection novel bioinformatics approaches that include knowledge discovery and machine learning will be used to integrate and analyse multidisciplinary datasets to assess the individual and combined impact of factors on disease phenotype information on the deep characterisation of the dynamics of the immune responses to the chosen viruses and identified factors critical for viral control and immune protection will be made available on a dedicated project website to clinicians researchers health authorities and public this will provide direct and immediate access to our findings for further development of personalised treatment therapeutic targets and vaccines in future trials and clinical practice to improve the wellbeing of the eu population and beyond
useroriented solutions for improved monitoring and management of biodiversity and ecosystem services in vulnerable european seas

the biodiversity health and services of european marine ecosystems is severely threatened as cumulative human pressures and impacts continue to spread and increase throughout our seas and along our coasts in order to put biodiversity on the path to recovery and thus achieve the ambitious policy goals set out by the eu green deal and the biodiversity strategy 2030 we need well informed science advice and operational decisionsupport tools allowing endusers to decide on conservation actions for biodiversity protection eg mpas while at the same time seek to minimize tradeoffs with other human use of ocean space eg fishing off shore energy and shipping buseful will develop and deliver useroriented solutions fit for uptake and implementation in decision making by effectively building upon existing european data infrastructures and governance frameworks for ecosystembased management advice and marine spatial planning this will be achieved by delivering upon the following objectives here presented in short form addressing the expected outcomes and impacts of the call and destination namely to i identify enduser needs ii codevelop biodiversity indicators targets and scenarios iii create a standardized biodiversity and pressure data base iv assess the status and cumulative impacts on biodiversity v quantify risk and vulnerability to biodiversity loss vi perform model forecasts of changes in biodiversity and ecosystem services vii codevelop an interactive online decisionsupport tool fit for management strategy evaluation of actions ensuring biodiversity protectionthe project will embrace a process of cocreation where all outputs are iteratively codeveloped validated and approved by endusers this serves not only to build mutual trust and credibility but also facilitate direct uptake and implementation of the useroriented tools and knowledge within operational decisionmaking for marine management and conservation
from housing inequality to sustainable inclusive and affordable housing solutions

highly ambitious in its objectives and scope and innovative in its focus conceptualisation and methodology equalhouse is the first research project to integrate all dimensions of housing inequality into one transdisciplinary and transnational research design by analysing the many aspects of housing inequality hitherto largely studied separately it will make key contributions to understanding of housing inequality and how it can be tackled and respond comprehensively to the work programme prioritiesequalhouse is designed to identify the most significant dimensions of housing inequality across europe clarify their scale form causes and consequences and provide local regional national and european policymakers with robust guidance on how to address these inequalities in a sustainable inclusive and affordable way it will analyse the scale form and dynamics of housing inequality comprehensively across the eu27 and uk identify its new acute and intersectional forms and explore its interaction with income and wealth inequality the policy regulatory service and finance drivers of and solutions to housing inequality will be examined in both national and international perspective equalhouse will propose solutions to address acute intractable and new forms of housing inequality such as unaffordability homelessness among refugees and migrants labour market related housing inequalities and energy povertyequalhouse starts by considering policymakers and implementers concerns and involves them as partners in cocreating both the research and solutions to housing inequality rather than relegating the production of these solutions to the project endstage and generating and communicating them in a top down manner to achieve these ambitious objectives equalhouse brings together a diverse and expert team of academics from across europe and disciplines and housing policymakers providers and enduser representatives
the arabic roots of european biology

this threeyear research and training project will throw new light on avicennas creation of an influential yet neglected model for biological investigation which centres on the organic body ie the material constituent of living beings in his biology avicenna d 1037 combines a medical and a philosophical approach to the body on the one hand in a medical fashion he favours a bottomup approach to the organic body which is no longer considered the elusive substrate of the soul in the hylomorphic compound nor taken in an abstract or general sense but capable of acquiring its primary determination as a result of chemical interactions on the other hand the principles on which avicenna grounds his investigation of the organic body are still philosophical this combination brings to light the other crucial novelty of avicennas biology its cuttingedge methodology which combines direct observation with theoretical assumptions to implement his new biology avicenna revives botany and zoology by introducing the medical approach to the various forms of organic life into these sciences thereby using empirical observational methods within a philosophical model governed by theoretical truths that are in principle nonnegotiable this new paradigm for life sciences remains operative far beyond the middle ages the centrality of avicennas new biology and its relevance for the subsequent tradition has never been emphasized in scholarship the proposed project will fill this gap an accurate examination of primary sources is essential to disentangle the relevant theoretical issues at the core of this project thus the methodology of the proposed research will consist of a jointly philological and philosophical approach concretely this means that the study of the relevant philosophical and scientific issues will be based on firsthand acquaintance with untranslated unedited or poorly edited and understudied greek arabic and latin texts
the evolution of human gut microbiomes in the plastics era

the gut microbiome gm is essential to human health and its dynamics allow for compositional and functional changes giving it the potential to help hosts to adapt to rapidly changing environments although there is growing concern and public pressure to understand the impacts of increased plastic pollution on human health a detailed assessment of this xenobiotics impacts on gms is a major gap in research that this proposal seeks to bridge i hypothesize that given a human exposure to plastics began very late in human evolution at the turn of the 20th century b this exposure is ever increasing and c preliminary results from my previous research show associations between plastic ingestion and changes in gm diversity and compositions then plastics likely play a role in shaping gms and their functions in modern humans i aim to test this hypothesis by 1 determining the prevalence of plasticdegrading pd microbes and functions across modern gms in order to 2 validate and characterize in vitro a subset of candidate gut microbes capacity for previously unidentified pd to finally 3 investigate plastics as a modulator of modern gms this will unveil unexplored factors behind the evolution of human gut microbiomes that could lead to the discovery of new plastic degrading microbes relevant for plastic pollution remediation strategies this project takes an unconventional and multidisciplinary approach by exploiting advances in microbiome research encompassing bioinformatic tools and databases applying these to the plastics field and targeting humans by building on my existing skills in wildlife and microbial ecology and plastics research and expanding them into human and computational metagenomics strengths of the host i am confident that plasticome will enhance my academic profile at the unique crossroad between metagenomics and plastics research allowing me to grow into an independent group leader
persianate jews mobility community memory

who are persian jews and what can we learn from their history looking back on a history of almost 3000 years the majority of jews left the persianate world from the mid20th century onwards as jews who lived in muslim cultures their trajectories do not fit into mutually exclusive concepts of jews and muslims however we hardly know how interactions between muslims and jews worked on a daily basis because the contemporary narratives about jewishmuslim relations tend to be highly polarized and access to sources in persianate societies is hampered based on different forms of interconnectedness this research provides the first comprehensive study about persianate jews from the 19th century until today it analyses jewish contacts within and outside of their communities in everyday life to shed light on the various forms of connecting with and separation from the surrounding muslim societies it highlights religious identity as applied in context rather than as fixed notion this can only be achieved by an innovative method of combining a variety of sources that have not been brought into dialogue until now including the different languages persianate jews used focusing on nonelites and everyday life also includes a completely new pool of data that until now was considered too mundane for analysis yet exactly these documents from ordinary people and daily encounters provide significant new insights into jewish life in the region the role of transregional networks and their connection to global markets in this way the project aims to overcome the geographic disciplinary and linguistic separation that has shaped modern persianate jewish history to date expanding this method systematically to a number of different archives will generate significant new insights on jewish life in the region present jews as active members of persianate societies and contribute to preserving an endangered cultural heritage
sharing the pronoun extreme violence social resistance and the shaping of cultural memory in spanish american contemporary documentary poetry

shape proposes a new cultural approach to the study of 21st century spanish american documentary poetry as a form of social and community resistance in the shaping of a shared memory about extreme violence in latin america this is a peculiar type of poetry using in the very body of the poem a variety of ethnographic historical archive texts chronicles visual audiovisual and virtual documents that have not been created by the poet the use of those texts in an intimate and nonmimetic code such as poetry determines a stylistic shortcircuit which has developed in different forms across all latin america in this context documentary poetry has been commonly used to verbalise the tragic consequences of the systemic institutional and noninstitutional forms of violence against women migrants indigenous or lgbtq people in spite of the key social function this poetry has assumed in latin america in recent years no comprehensive study has been produced on it yet shape aims to fill this gap by building a model of interpretation of documentary poetry not only as an aesthetic expression but also as a powerful tool to preserve and construct social memory about suffering to that aim shape intends to adopt an interdisciplinary methodological approach involving literature cultural studies cultural history and ethnography in order to investigate how this poetry contributes to the processes of resistance to extreme violence due to the intertextual nature of documentary poetry my expertise in intertextuality and genre contamination is a key factor for the successful completion of the project the aim is to generate a new crosscultural conceptual reflection on how to use literature to resist new forms of racial and social discrimination thanks to this msca grant i will strengthen my academic profile by acquiring the relevant competences to offer a new wider perspective on how to view the problem of social and institutional violence in latin america
a transfer of knowledge and technology for investigating genderbased inappropriate social interactions in the metaverse

the metatoo proposal underscores the knowledge and skills transfer from two distinguished european institutions inria and idibaps each renowned for its research contributions in the digital forefront to the national and kapodistrian university of athens nkua greece serving as the coordinating institution representing a widening country greece specifically both inria the french national institute for research in computer science and automation and idibaps fundaci de recerca clnic barcelona in spain have earned global recognition for their outstanding contributions to extended reality xr research it is precisely within this domain that we have elected to focus the support of inria and idibaps henceforth called mentors for the national and kapodistrian university of athens coordinator with a concerted effort aimed at reinforcing research management and administrative competencies alongside enhancing research and innovation capabilities