Dragon09/odtu_chatbot huggingface dataset:
compatibility assessment of nonsteel metallic distribution gas grid materials with hydrogen

green hydrogen is gaining moment across europe as feedstock fuel or energy carrier and storage as solid actions are needed to reach carbon neutrality by 2050 hydrogen has many possible applications across industry transport energy and building sectors and therefore local gas grids across europe are working hard to get ready for its transport the realization of the prospects of delivering h2ng admixtures or even 100 h2 by existing gas distribution grids exacerbates the problem of pipe integrity due to the wellknown negative impact of hydrogen on the mechanical properties of metalsmost projects assessing safe hydrogen compatibility with natural gas distribution grids ie h21 hydeployetc have performed experiments to study the leakage ratio emission potential and explosion severity of vintage components however longterm material integrity assessment replicating distribution grid operating conditions in testing platforms is still necessary candhy will allow the possibility of testing relevant metallic materials different from the wellstudied steels with a methodology involving simultaneous test in independent rd platforms with a common methodology this will allow to obtain trustful and reproducible results about hydrogen tolerance of materials that have not been considered in previous research but that are an essential part in in lowpressure gas gridscandhy project will enable hydrogen distribution in low pressure gas grids by consolidated and exhaustive scientific data coupled with harmonized guidelines for nonsteel metallic grid materials at least five material grades of different families such as cast iron copper brass lead aluminium both new and vintage will be fully documented and the results will be publicly available for all stakeholders in a continuously updated database mechanical tests will base on static and dynamic conditions to assess hydrogen sensitivity following the most relevant current and updated standards
smart aware integrated wind farm control interacting with digital twins iconic

iconic aims to develop innovative physical and digital tools to achieve fundamental breakthroughs for the integrated control of wind farms considering the whole physical system at farm turbine and component levels in particular the complex aerodynamic interactions among turbines iconic aims to increase farmwide power production by 1520 under optimal wind speeds and directions for typical wind farms suffering from wake effects with a 35 increase in annual energy production aep considering all working conditions over the long term it targets an lcoe reduction of at least 6 compared with the stateoftheart control tools deployed in the current wind industry by improving farmwide aep and reducing operation maintenance costs via leveraging the latest ai and digital technologies extensive validations for the integrated wind farm control solutions will be conducted via highfidelity simulation models experiments at a nationallevel wind tunnel historical operational data at bps and cpowers wind farms a unique collection of test rigs for critical turbine components at respective companies and realworld wind farm field tests at cpower iconics integrated wind farm control system will contain 1 novel aibased wind farm control system to unlock wind farms full potential 2 novel dataenhanced wind turbine controllers to fulfil farmlevel commands while balancing power generation and load mitigation 3 an integration with digital twins dts as extra support to improve control and reduce costs which contains a firstever farmlevel dt for wind farm flow systems replicating detailed physical flow fields and an innovative turbinelevel dt with critical component models for loading and lifetime estimations 4 extensions of the solutions to future 20mw turbines iconic will establish new knowledge and industrial leadership in key digital enabling and emerging technologies and deliver nextgeneration tools for wind farm operation
lightcure light for double specificity and efficacy without burden

congenital hyperinsulinism chi is a group of rare diseases of newborns and infants with functionally defective nonneoplastic betacells that cause hypoglycemia and severe morbidity through oversecretion of insulin chi is a major cause of hypoglycemic brain injury with intellectual disability epilepsy and cerebral palsy as no registered causal therapy exists management of chi aims at increasing blood glucose levels causing severe side effects in all patients while lifethreatening frequent hypoglycaemias remain removal of hyperfunctioning beta cells by pancreatectomy leads to insulin dependent diabetes mellitus iddm and maldigestion of food changing one disease for another with severe secondary morbidity management of chi is choosing between evils and symptomatic management is partially effective in only some subtypes chi also represents a major burden for families because of disability but also as a result of continuous monitoring and correction of glucose levels for many years requiring permanent alertness health problems and economic decline occur in most parents a normal life is not feasible for families with babies with chi lightcure consortium partners have demonstrated the feasibility of selectively targeting beta cells using exendin 4 ex labelled with a photosensitizer 700dx specifically binding to beta cells this photosensitizer can be activated by light of a certain wavelength and will produce radical oxygen species leading to cell damage a principle called targeted photodynamic therapy tpdt in this project we will build on existing cuttingedge technology exclusively available to the consortium partners and perform human proof of concept studies demonstrating safety and efficacy of tpdt with ex700dx we will deliver the proofofconcept that after injection of ex700dx minimally invasive tpdt leads to normalization of blood glucose levels avoiding morbidity enabling a normal life for babies with chi and their families
systematic analyses and rational engineering of fast co2 fixation pathways in living cells

biological co2 fixation is the primary process responsible for biomass and food production and a key player in the atmospheric co2 balance almost all biological co2 fixation is caried out by a single pathway the calvin cycle despite the dominance of this pathway in nature it seems relatively inefficient due to high energy costs and poor enzyme kinetics an exciting option to improve this efficiency is the exploration of potentially more efficient synthetic co2 pathways however a key challenge to identify promising synthetic co2 fixation pathways is the limited availability of kinetic data on relevant enzymes in addition kinetic data are usually measured in vitro and hence not always representative for the performance in living cells in fastfix i will develop and use a novel method to quantify kinetics of enzymes within living cells i will do this by making the growth rate of engineered escherichia coli cells directly dependent on the kinetics and levels of the enzymes of interest by measuring the growth rates and enzyme levels by absolute quantitative proteomics the in vivo kinetics of the enzymes can be determinedthis approach will be used to generate a complete overview of the kinetics of enzymes involved in promising synthetic co2 fixation pathways this will enable an unprecedented systematic analysis of the kinetics of synthetic co2 fixation pathways based on this analysis i will select the most promising pathway design enabled by the in vivo kinetics data i will then employ a novel forwardengineering method to effectively engineer and demonstrate the performance of the full pathway in e coli the realization of a fast energyefficient synthetic co2 fixation pathway in living cells will be a major milestone the anticipated results will be promising for efficient co2based biotechnological production and in the longerterm may increase agricultural yields and help to more efficiently mitigate humanitys co2 footprint
fate of reduced organic sulfur

arctic suffers of the global warming and as a consequence ground and surface waters are more and more mixed increasing microbial activities because ros are present in all living organisms as amino acids ie cysteine and methionine increasing microbial activities induce increasing production of reduced organic sulfur ros and organic matter om some metals and metalloids me have a large affinity for ros ie pt2 pd2 hg2 cd2 asoh3 sboh3 leading to the formation of rosme complexes the presence of ros modifies thus the fate speciation ie all chemical and physical forms bioaccumulation and toxicity of me rate of ros and rate of me are interconnected aquatic living organisms produce ros in response to me stress in order to modify the speciation of me which in turn modifies the bioaccumulation and toxicity of me despite the interconnections of me and s biogeochemical cycles such rosme forms are neither quantified i in the environment ie water ii nor in laboratory ecotoxicological studies iii or in ecotoxicological modelling and iv only partly in laboratory geochemical experiments ie only the model i developed in 2015 consider as association to reduced s of om in fate ros we will elucidate rosme associations through analytical developments dedicated to natural waters which will be able to quantify ros speciation in boreal waters including high arctic thanks to a coupling of original experimental and spectroscopic results a toxicogeochemical model will then be developed to predict the toxicity of me and meros a successful scientific and training project is expected due to a cleverly thought 3waytransfer of complementary skills in between me my supervisors of the host institution hi and the partner institution pi such as me geochemistry knowledge me s biogeochemical cycle and fate in arctic context pi and finally me toxicity hi
heterogeneous integrated shortwave infrared colloidal quantum dot lasers

irqual addresses the critical need for compact integrated lasers operating in the shortwave infrared swir spectrum 13 25 m for diverse applications such as consumer electronics automotive iot and arvr specifically lasers in the eyesafe window around 14 m and 2 m are crucial for lidar systems 3d face recognition and environmental monitoring current technologies including solidstate lasers and iiiv semiconductor laser diodes face limitations in size cost performance and scalability irqual aims to develop a versatile heterogeneousintegrated laser platform this platform will exploit swir cqd laser technology pumped by established gaasbased highpower laser diodes to develop a device that covers the range 15 to 25 m irqual will further focus on the commercialization and exploitation of the technology described above to achieve this aim efforts will be made to develop a strong intellectual property portfolio and also engage with leading industrial figures that could assist in the development and validation of the technology achieving irquals objectives will revolutionize swir light applications enabling widespread use in automotive mobile phones machine vision and sensing eyesafe illumination systems aligned with safety standards will further enhance commercial prospects the technologys lowcost and compatibility with consumer electronics laser technology will transform lidar 3d imaging and remote sensing contributing to a significant socioeconomic impact in essence this project pioneers a new era in swir laser technology introducing unprecedented compactness costeffectiveness and scalability for a multitude of highimpact applications
model theory locally compact groups and solution of hilberts 5th problem

the main goal of the project is to apply advanced techniques from the model theory a branch of mathematical logic to the class of locally compact groups arising from the solution of hilberts 5th problem so at the end to the class of lie groups to answer the following question how much geometry can model theory recognize there does not exist a general firstorder modeltheoretic description of the locally compact groups thus our first goal will be to develop such a description then we will study how notions from these two corners of mathematics ie model theory and locally compact groups correspond to each other for example we will try to enrich the classification of locally compact and lie groups by translating the dividing lines from the modeltheoretic stability hierarchy in the next stage machinery from the so called geometric neostability theory will be deployed in a tame class of locally compact groups for example in the class of locally compact groups being projective limits of lie groups and not having small subgroups so in the groups from the solution of hilberts 5th problem in this spirit one could consider the definable homogeneous space coming from the group configuration theorem which is a part of the aforementioned machinery and try to relate it to the unsolved hilbertsmith conjecture this will be one of our milestonesin short we aim to find connections between modeltheoretic theorems of geometric nature and classical theorems on the lie groups so theorems which depend on the geometry of lie groups after understanding these connections we want to transport techniques from the model theory into the locally compact and lie groups and vice versa
strengthening the integrated approach of holistic impact assessments for safe and sustainable by design plastic value chain

analyst aims to accelerate the transition towards a safer and more sustainable industrial value chain while encouraging and expanding the existing knowledge on the safe and sustainable by design ssbd framework in this vein the project develops and implements 3 different innovations figure 1 innovation 1 i1 analystbox creates robust and consistent methodologies and guidelines for integrative health environment social and economic impact assessments of pvc materials at the eu and global scale innovation 2 i2 analystdigi is an open platform intended to embed both the digital multicriteria decisionmaking support tool dmdms and a large number of resources results of the validation program training actions and materials and other dissemination and communication resources the dmdms uses an owngenerated cohesive and interoperable database that combines different data sources lastly innovation 3 i3 analysttpack comprises a validation program trl5 with 3 different use cases covering the whole pvc value chain namely suspensionpvc flexible emulsionpvc flexible and suspensionpvc foamed rigid of the automotive and construction sectors the goal is to support impactbased informed investment decisions the ssbd framework and the implementation of policies for future chemicals and materials through an improved understanding of potential sustainability tradeoffs all in all analyst will catalyse and empower the industrial sector to achieve the paradigm shift towards chemicals materials and products that are inherently safe and sustainable it will drive forward the new industrial strategy for europe the circular economy action plan and the chemicals strategy for sustainability css while fully aligning with the european commissions green deal for cleaner and more climateneutral industrial value chains
the best way to know your health we have integrated a medical device into a toilet allowing people to take an autonomous exam related to several health parameters with simplicity and regularity

abluteis the best way to know your health by integrating a urinalysis device into a waterefficient toilet people can take exams with the simplicity of using a bathroom regular screening is the most reliable method to early detect diseases ablute delivers simplicity to health examination fostering regularity the equipment analysis several biomarkers simultaneously and delivers immediate results via software if a sign of a condition is detected an alert is emitted catching the physician and patients attention to that condition at its early stagesthe data transmitted is used for accessing patients health but also for rd purposes on one hand the biomarkers related to the analysis of diabetes chronic kidney disease inflammation and hypertension are already standardized thus the medical community already accepts them as the common used mean to monitor and detect those conditions on the other hand the biomarkers endorsed by ablute for the analysis of 5 types of cancer breast prostate colorectal bladder and ovarian even though already validated by the scientific community with high levels of sensitivity and specificity are still in progress for being perceived as valid by the medical community ablute combine the analyses of these innovative oncological biomarkers with the standard ones delivering relevant information while working on further validation the toilet can be used for common purposes however in order to perform urinalyses the user needs to enable a connection by pairing it with an nfc device or through facial recognition once connected the toilet will open itself automatically and the person can use it like a regular toilet ablute completely automatizes the process of taking a health screen it collects a urine sample analyzes it and delivers the results ablutes goal is to democratise health examination step by step we are providing people with the necessary means to be the healthiest version of themselves
the global south in the age of early industrial capitalism commodity frontiers and social transformations 18161870

our lives would be unthinkable without the production of millions of tons of cotton sugar palm oil or soy all these commodities are obtained at the lowest possible price with often detrimental consequences for people and nature the scale of the resulting environmental crises may be something of recent making its mechanisms can be traced many centuries ago and are crucially part of the history of global capitalism this project will go back to the pivotal decades when europe recovered from the devastating napoleonic wars the industrial revolution picked up steam and global trade went through fifty years of rapid growth a spurt even more spectacular than after the opening of the suez canal in 1869 against this backdrop the projects research team will examine the immense transformative effects of commodity frontiers in the global south that fed the rise of early industrial capitalism we will assess these transformations by taking the seven most exported commodities from the global south as the unit of analysis sugar cotton coffee tea precious metals goldsilver opium and cereals we will map the wideranging and diverse social consequences of the massive mobilization of labour and land necessary to produce these commodities using an extensive historical database on global labour relations developed by an international group of scholars we will further examine how these commodity frontiers were organized and financed by using underutilized archives of prominent locally and globally operating merchant houses finally we will assess the actual contribution of the production of the seven commodities in the global south to the upsurge of global trade data mining from digitized sources such as newspapers will allow us to identify trade patterns that so far escaped historical statistics thus we will break new grounds in understanding how early on in the nineteenth century global trade and production patterns emerged that shaped the world of today
cell line engineering for imporved fertility treatment

kyronbio is a female led biotech company on a mission is to unclog bottlenecks in therapeutic protein production allowing better drugs to reach patients we are using synthetic biology to engineer mammalian cell lines for improved bioproduction harnessing highly efficient enzymes from diverse life forms our preliminary data demonstrates a 3x yield gain for the amount of therapeutic produced in our system with further gains in yield activity and stability predicted post optimisation
a lightweight software stack and synergetic metaorchestration framework for the next generation compute continuum

the vision of nephele is to enable the efficient reliable and secure endtoend orchestration of hyperdistributed applications over programmable infrastructure that is spanning across the compute continuum from cloudtoedgetoiot removing existing openness and interoperability barriers in the convergence of iot technologies against cloud and edge computing orchestration platforms and introducing automation and decentralized intelligence mechanisms powered by 5g and distributed ai technologiesthe nephele project aims to introduce two core innovations namely i an iot and edge computing software stack for leveraging virtualization of iot devices at the edge part of the infrastructure and supporting openness and interoperability aspects in a deviceindependent way through this software stack management of a wide range of iot devices and platforms can be realised in a unified way avoiding the usage of middleware platforms while edge computing functionalities can be offered on demand to efficiently support iot applications operationsii a synergetic metaorchestration framework for managing the coordination between cloud and edge computing orchestration platforms through highlevel scheduling supervision and definition based on the adoption of a system of systems approachthe nephele outcomes are going to be demonstrated validated and evaluated in a set of use cases across various vertical industries including areas such as disaster management logistic operations in ports energy management in smart buildings and remote healthcare services two successive open calls will also take place while a wide opensource community is envisaged to be created for supporting the nephele outcomes
worlwide hydrological largescale database

vortexio offers an innovative and intelligent service for monitoring hydrological surfaces using insitu remote sensing instruments based on compact lightweight altimeter inspired from satellite technology the microstations it provides in real time with a high frequency and accuracy hydrometeorological parameters water surface height water surface velocity images videos of the observed watercourses the combination of these insitu data with satellite measurements is thus optimal for downstream services related to water resources management and assessment of flooddrought risksthanks to the development of the innovative microstation and the onboard processing using artificial intelligence algorithms the whyld project will provide an anytimeanywhere real time hydrometeorological database to prevent communities from flood risks and secure goods anywhere at any time the project thus aims to cover the whole europe through a nonbinding turnkey service