Dragon09/odtu_chatbot huggingface dataset:
a molecular proxy for gender contrasts at the neolithic to bronze age transition

the project anthropyxx proposes an archaeogenomic exploration of the status and life of women and men during the key transitional period between the neolithic and the bronze age in occidental europe with the ambition to better understand the deep roots of gender contrasts in presentday societies inequalities today can be measured through economical markers health or education levels as these metrics are not directly accessible in prehistoric periods alternative proxies have to be exploited to trace back the emergence of inequalities including data from ethnoarchaeology and anthropobiology traditional isotopic analyses or the interpretation of funerary practices and artistic representation the project anthropyxx proposes to add palaeogenomics to the current gender archaeology toolkit more specifically anthropyxx aims at leveraging the latest advances in ancient genomics applied to a rich collection of protohistoric human remains and combined with isotopic data to better picture the contrasted life of women and men through the reconstruction of family structures inbreeding levels and residential rules the health status of the women and men and their associated microbes will be assessed the development of innovative approaches both on the bench and in silico will enable the characterization of past dna methylation levels and their comparison with modern data especially at positions impacted by adverse life conditions finally we will document the populations genetic heterogeneity and investigate the hypotheses of sex biases in population migrationsthe anthropyxx project will provide a new proxy to test if i health conditions reproductive behaviour as well as epigenetic environmental impact were contrasted between women and men during protohistory ii men and women contributed differently to the genetic makeup of european populations and iii these contrasts were exacerbated during the transition from the neolithic to the bronze age
reducing empiricism in luminescence models to measure rates of earth surface processes

feldspar luminescence is a diverse tool used to constrain the timing and rates of past changes of the earths surface but it is also key for understanding future landscape response under a changing climate novel luminescence techniques such as luminescence thermochronometry thermometry and surface exposure dating used to reconstruct rock cooling histories erosion rates and palaeotemperatures require the application of models describing charge trapping due to ionising radiation and luminescence decay due to heat or light stimulation however it has become clear that to improve the precision and accuracy of these approaches a much deeper understanding of the physics underlying these techniques is required the interdisciplinary project reducing empiricism in luminescence models to measure rates of earth surface processes recreate combines solid state physics and geosciences recreate aims at accurately constraining physical parameters in the feldspar lattice governing luminescence production and to develop a unified physically correct feldspar luminescence model to be used in luminescence thermochronometry and thermometry studies with the overall goal of making feldspar luminescence techniques and applications more accurate transparent and widely applicable
prehellenic loanwords in greek lexicon of the substrate analysed

philoglossa aims to provide a critical reassessment and analysis of the loanwords borrowed into the ancient greek language of from the prehistoric languages early greek speakers encountered in the bronze age aegean these prehellenic or pregreek loanwords have long been recognised to constitute a significant layer in the greek lexicon the earliest of which are already present in mycenaean greek attested by linear b documents despite the phenomenon being well known the historical origins and linguistic interpretation of these loanwords have remained controversial and attempts to explain them as from a single source as per the interpretational framework of the latest controversial etymological dictionary of greek 2010 leiden by robert beekes has been fraught with methodological problems philoglossa will build an openaccess linguistic database to facilitate a fresh analysis of the material that will be conducted as the main research activities of the project as new archaeogenetic studies have provided new evidence strongly suggesting intensive and sustained social and cultural interaction between the incoming early greek speakers and the earlier inhabitants of the aegean it is of crucial importance to reevaluate the linguistic evidence for these exchanges preserved in the ancient greek language as such the results of philoglossa will be of interest not only to those interested in the history of the greek language but also to indoeuropean comparative linguists aegean prehistorians archaeologists and geneticists more broadly
mathematics of boseeinstein condensation

we propose a project in mathematics with a focus on manybody theory in mathematical physics we are especially interested in themathematical tools involved in the description and analysis of the recent experimental realizations of boseeinstein condensation itremains one of the most important challenges of mathematical physics to rigorously understand the formation of condensatesin interacting systems this project aims to address that challengeprogress on the problem of condensation has been made on certain length scales and we aim to push the boundaries of theselengths with a view towards the endgoal of actually having a mathematical proof of condensation in a continuum system ofinteracting quantum particles in the thermodynamic limit to approach this objective we will study various related systems andproblems with the expectation of getting improved understanding by seeing the methods in a new light to fully solve these simpler problems will require the development of new mathematical tools and the gain of critical insight some of these simplified problems are concerned with the energy of the bose gas in the dilute limit also in dimensions different from 3 as well as lhyphysicsspecially prepared systems where the normally lower order correction terms become dominant
unravelling the socioeconomic and environmental impacts of circularity in latin america

in unravelling the socioeconomic and environmental impacts of circularity in latin america unica i will explore the socioeconomic and environmental implications of a latin america latam circularity transition and its impact on the eu economy using my expertise in assessing global circularity i will contribute to understanding the potential tradeoffs of a circularity transition from a multiregional perspective which provides essential information to enhance the implementation of circular strategies in the upcoming decade unica will allow me to foster my career in two main ways 1 i will become an expert in the circularity transition in the global south and its connections with highincome countries and 2 i will be able to develop a hybrid career where i will be able to contribute to academic and nonacademic institutions simultaneously
reading provenance from ubiquitous quartz understanding the changes occurring in its lattice defects in its journey in time and space by physical methods

quantitative provenance analysis studies are instrumental in understanding the tectonic and climatic processes that are shaping earths landscape although the most abundant mineral in the sedimentary system is quartz almost all studies in provenance analysis investigate accessory minerals quartz crystals contain a vast number of point defects intrinsic or due to impurities although our understanding on the formation and dynamics of these defects is far from complete a few of these defects in quartz are used for dating quaternary sediments by luminescence thermoluminescence tl or optically stimulated luminescence osl or by electron spin resonance esr progress aims at proving that point defects in quartz have also the capacity to carry genetic information and their modifications can provide evidence for antiquity metamorphism or lack thereof as well as knowledge on weathering transport or recycling this information can be unravelled by esr and luminescence methods in combination with microscopic techniques such as scanning electron microscopy coupled with cathodoluminescence cl wavelength resolved spectroscopy to understand changes that are occurring at atomic level in quartz in nature in geological time progress will investigate quartz grains extracted from independently dated old to young quartzbearing continental crustal sources metamorphosed rocks versus their unmetamorphosed equivalents fresh versus highly weathered samples as well as intrusive versus volcanic rocks besides conducting experiments in laboratory environments to tackle natures complexity during sediment movement in space and time the effect of physical and chemical changes that occur during transport of quartz grains will be investigated by the study of river sediments that drain different lithologies these investigations will allow a simple quartz based fingerprinting method to be developed that will have a significant impact on quantitative provenance studies
safe and sustainable lowcarbon fuels for heavyduty aviation and maritime sectors

heavyduty vehicles including nonroad mobile machinery eg excavators aircrafts and ships are contributing significantly to emissions of greenhouse gases and healthrelevant air pollutants such as fine airborne particulate matter pm25 as well as emerging pollutants for decarbonization of the sector several new fuels ranging from hydrogen via ammonia to synthetic efuels are considered an import question is how these potential new fuels will influence the emission of air toxicants and other environment and climateactive compounds lowc will address if these new fuels for highpower engines have an impact on the emissions of air pollutants and climatedrivers considering also upstream emissions and secondary pollutants formed under different atmospheric conditions daytime photochemical aging or nighttime atmospheric radical chemistry lowc will apply a series of stateoftheart technologies and models this includes a unique engine emission facility equipped for testing of all currently considered low or zerocarbon fuels with real ship aircraft and landbased heavyduty engines oxidation flow reactors for atmospheric simulation novel realtime insitu exhaust characterization approaches cuttingedge technologies for offline analysis of collected samples and advanced online airliquidinterface ali exposure systems for in vitro testing of biological effects in lung tissue models the toxicological testing will be applied in a tiered manner screening and indepth verification in line with visions of toxicity testing in the 21st century emission data including regulated and emerging pollutants will feed into pollution emission and atmospheric transport models currently used to underpin eu policy and the zero pollution action plan finally lowc will evaluate health and environmental impacts and provide guidance and recommendations to ensure that solutions to reduce co2emissions and prevent climate change are safe and sustainable
the german democratic republics jewish diplomacy and coming to terms with the past

the project offers an examination of the german democratic republics gdr contacts with jewish organizations communities and individuals in nonsocialist countries that took place as of the 1950s until the fall of the berlin wall in 1989 as an essential component in the development of an east german notion of coming to terms with the past vergangenheitsbewltigung the project is the first to set the primary focus on jewish communities of different types as a target group of the gdr international relations by initiating these contacts the gdr developed distinctive political and ideological approaches to dealing with the national socialist past different from those developed in the federal republic throughout the 40year existence of the gdr exchange with jews and israelis was influenced by the east german stance towards zionism as well as by geopolitical dynamics of the cold war and the soviet unions interests in the middle east conflict this research project aims to fill a significant gap in the existing body of knowledge on contemporary german and european post1945 history the project also unveils a multitude of reactions from jewish and zionist players in response to the east german political approach towards its own history jews zionism and israel importantly this project introduces fresh perspectives on the concept of coming to terms with the past particularly in light of the contemporary surge of rightwing populist trends in germany and europe
neuroactive compounds in tomatoes and their role in the development of neurodegenerative diseases via the gutbrain axis using a multiomics approach

neurodegenerative nd diseases are debilitating and largely untreatable conditions that affect millions worldwide including 7 million europeans although there remains no cure there is growing evidence of a correlation between diet gut and nd diseases but a deeper understanding of what happens to neuroactive compounds once digested and their role in the communication between gut and brain is still missing in response neurotom will answer complex questions about human exposure to neuroactive compounds using tomato as a model food such as what happens to these chemicals during digestion and their role in the gutbrain axis and nd disease development it will use advanced mass spectrometrybased techniques to characterise neuroprotective and neurodisrupting compounds in tomatoes produced organically conventionally and processed an in vitro batch colon model will then be applied to investigate the fate of these compounds in the gut microbiome and identify gutmicrobial metabolites a step towards more realistic conditions will be made by investigating how the presence of neurodisrupting compounds influences the bioavailability and beneficial effects of neuroprotective compounds in the gut selected compounds will also be tested using an innovative in vitro 3d colon organoid model to determine the role of neuroprotectivedisruptive compounds and their gut microbial metabolites on intestinal epithelium cells the proposed research is highly interdisciplinary and encompasses analytical and food chemistry holistic and multiomics approaches nutritional biochemistry biotechnology and aspects of neuroscience the goal of neurotom is to extend the knowledge of dietgut microbiomehost brain interactions and will contribute towards preventing or alleviating the burden of nd disease
natural microbial interactions in winemakingassociated ecosystems as a tool to foster wine innovation

the eco2wine project aims at providing a new generation of phd graduated employees for the wine sector who will be able to manage winemakingassociated ecosystems protect and control the biodiversity and use this knowhow to reduce unsustainable interventions in natural environments while improving wine sustainability and natural wine production winemakingassociated ecosystems are complex environments in which more or less stable and evolutionary relevant interactions among species and between each species and abiotic components are established in recent years the direct manipulation of these ecosystems has gained considerable interest in wine science because of the need of boosting sustainable socially relevant and ecofriendly choices for the wine production while meeting the growing consumer demand for more diverse wine styles to better map and exploit the natural biodiversity of winemakingassociated ecosystems the understanding of the relevant microbiota the various ecological interactions within those biota and of the molecular mechanisms involved in interactions is essential such studies will allow to describe how these ecosystems work and how their intelligent exploitation can benefit the wine world the training program is divided in 4 areas of interest wine ecology wine innovation wine business and wine science communication the consortium includes 9 beneficiaries and 12 partner organizations that possess complementary competencies and are working with success in wine research the level of quality of these institutions the longterm collaborations established in the past joint european project yesvite ga612441 and the appropriate exchange scheme of training with private companies will sustain an efficient transfer of knowledge between phd students the broader scientific community and the relevant social and economic actors the project will have a relevant impact on the wine research field winemakers and all potential stakeholders
multidisciplinary and multiscale approach for coupled processes induced by geoenergies

geoenergies such as geothermal energy co2 storage and underground energy storage have a great potential to contribute to meet the paris agreement targets on climate change yet their deployment has been hindered by a lack of a full understanding of the processes that are induced in the subsurface by largescale fluid injectionextraction the various processes involved eg fluid flow geomechanical geochemical and thermal effects imply complex interactions that cannot be predicted without considering the dominant coupled processes which is rarely done as a result some early geoenergy projects have occasionally developed unpredicted consequences such as felt and damaging induced earthquakes gas leakage and aquifer contamination dampening public perception on geoenergies smile aims at overcoming these challenges in developing geoenergy solutions by training a new generation of young researchers that will become experts in understanding and predicting coupled processes thus they will be capable of proposing innovative solutions for the successful deployment of subsurface lowcarbon energy sources while protecting groundwater and related ecosystems to achieve this ambitious goal the earlystage researchers will be exposed to an interdisciplinary training on experimental mathematical and numerical modelling of coupled processes upscaling techniques and ground deformation monitoring using field data from highly instrumented pilot tests and industrial sites the training in smile has been designed by both academic and industrial partners to train competitive researchers with both technicalscientific and transferable skills to enhance their employability in academia industry and public sector the outputs of the project will be largely disseminated outreach to society will be achieved through a conspicuous series of initiatives smile will make a significant contribution to the societal challenges of securing clean and lowcarbon energy sources
observing and mapping marine ecosystems next generation tools

obamanext aims to develop a toolbox for generating accurate precise and relevant information characterising marine ecosystems and their biodiversity this will be achieved by integrating newemerging technologies including remote sensing edna optical instruments and citizen science with existing marine monitoring techniques for improving our capacity to describe ecosystem function and biodiversity with higher spatial and temporal resolution the project will contribute to shaping next generation monitoring programs and defining essential oceanbiodiversity variables eovsebvs stakeholders will be involved from the onset of the project to identify products needed in an iterative cocreating and specification process these specifications will guide the application of algorithms including advanced statistical analyses and artificial intelligence which combine and translate different data sources into information products ie maps and indicators to fulfil stakeholders needs routines for visualisation and methods for uncertainty assessment are also important components of the toolbox development the toolbox will be evaluated and improved based on 12 selected learning sites ls representing diverse ecosystems and data sources within the four european regional seas the applicability of the information products compiled with the toolbox on ls data will be evaluated as input to models for predicting biodiversity and as support for environmental and biodiversity policies the project will also assess the usefulness of the products with respect to the eu objective of designating an ecologically coherent mpa network and the applicability of cburial rates in angiosperm habitats for carbon offsetting and nationally determined contributions obamanext will strengthen europes capability in acquiring and utilising biological ocean observations for better management of marine resources through strong public outreach and active stakeholder communication
antiviral therapeutics for rapid response against pandemic infectious diseases

the european consortium antiviral therapeutics for rapid response against pandemic infectious diseases avithrapid aims to support the search for novel broadspectrum antiviral compounds by advancing multiple approachesbuilding on a preexisting set of bioactive small molecules which are at least at the validated hit level avithrapid strives for the development of preclinical candidates targeting several viruses this will be achieved by combining the relevant expertisefor preclinical drug discovery including molecular modeling biochemical and cellbased assays xray crystallography medicinal chemistry biophysical binding studies admetox profiling in vitro and in vivo pk as well as animal disease models in addition the consortium aims to conduct a phase 2a clinical trial for a small molecule developed against zika virus moreover the consortium aims to identify and validate further viral targets and thereby contribute to the search for novel antiviral targets as a consequence of the activities in avithrapid an earlystage drug discovery pipeline will be established that can be used to rapidly identify and develop novel antiviral compounds against emerging diseases
multiscale investigation of the chemistry of the atmosphere of venus

venus is the closest planet to earth despite a similar size and mass there are differences between the two planets at the surface the temperature can reach 730 k with a pressure of 90 bar and a composition of 96 of carbon dioxide venus hosts a global cloud layer between 45 and 70 km of altitude with composition and temperaturepressure conditions close to the earths stratosphere and complex chemistry with both sulphur and water cycle this global cloud layer plays a key role in the radiative equilibrium of the atmosphere therefore it is fundamental to study its composition and dynamics at all spatiotemporal scales to understand the atmosphere of venus despite decades of measurements and modelling there are still many unknowns about the chemistry of the venusian atmospherethe project musicav multiscale investigation of the chemistry of the atmosphere of venus conducted at latmos will develop new and ambitious numerical models using a hierarchy of models a planetary climate model pcm mesoscale and largeeddy simulation les models all coupled to a photochemistry scheme these three models are performed with different resolutions and would help capture the spatiotemporal variability of the chemistry over different scales as never before and will increase the understanding of the coupling of the dynamics and chemistry from the largescale to the smallscalesthe proposed effort is perfectly timed and relevant to ongoing and planned international venus exploration activities esa mission envision and nasa missions davinci and veritas were all three selected to launch in the next decade the main objectives of these missions are to study the surface and the dynamics both inside and below the clouds the project will simulate predictions for chemistry variabilities to produce observables for past and future missions to improve the interpretation of the measurements