Dragon09/odtu_chatbot huggingface dataset:
hebrew philosophical manuscripts as sites of engagement

in the middle ages philosophical activity undertaken in hebrew was not conducted within an institutionalized environment there were no universities regulated curricula or professors but only small circles of scholars most of whom we know nothing about these scholars had to obtain their own copies of the works they wished to explore sometimes even copying them themselves or with the help of others heavily involved in the production of the materials they were using they often interfered with the texts they were studying offering corrections working notes glosses comparisons and observations as a result the corpus of philosophical writings in hebrew is incredibly diverse and rarely is one copy similar to another in this challenging landscape the individual copy is our main entry point for understanding how hebrew philosophy took place in the real world the hebrew philosophical manuscript is not a mere container of text more than anything else it is a site of engagement aside from a few notable exceptions scholarship of philosophy in hebrew is still focused on a relatively small number of major thinkers and works manuscripts are often stripped of their particularity and employed only for the sake of producing critical editions the story of the silent nameless majority who enabled philosophical activity by tirelessly editing studying translating revising and producing the material hebrew philosophical corpus we have today has yet to be told hepmasite is the first project to tackle the corpus of medieval hebrew philosophical manuscripts in order to unravel the hidden history of jewish philosophy enveloped within them by employing narrative philology and a historiography of engagement novel research methodologies that embrace textual particularity and fluidity hepmasite will revolutionize the understanding of jewish philosophy as it took place in the real world and as it was studied by actual people
scaledup production of nextgeneration carbohydratederived building blocks to enhance the competitiveness of a sustainable european chemicals industry

the platform chemicals sector is currently highly dependent on fossilfuels the small volumes of current biobased platform chemicals are reliant on sugarstarchoil crops which diverts them from food uses and there are also high environmental impacts linked with their landuse and supply cycles lignocellulosic feedstocks particularly residues are more sustainable but to date the range of chemicals that have been demonstrated atscale from these has been limited in particular there are a range of functionalities associated with fossilderived platform chemicals that current biobased chemicals cannot replicate bioneer addresses this issue by demonstrating production of a new range of carbohydratederived building blocks and platform chemicals at trl67 a selection of additional functionalities obtained through carefully controlled optimised modifications and involving both chemical and enzymatic approaches are conferred to the new building blocks that for the first time atscale allow for the massmarket substitution of fossilderived chemicals in a range of application markets bioneer builds on the trl45 advances made in the development of resource and energyefficient processes for the production of these building blocks in prior projects the bioneer consortium and advisory board covers all stages of the value cycle ranging from the sourcing of sustainable feedstocks to the extraction and modification of biomass fractions leading to the production of building blocks that are then application tested in the uvcuredcoatings and personal care sectors by industrial partners safety and sustainability aspects are integral to bioneer which follows and seeks to improve the eus safeandsustainablebydesign ssbd framework it is expected due to the involvement of key technology developers and industrial partners that the bioneer technologies will be rapidly commercialised postproject
a european proactive adaptive clinical trials network within euresponse

recent pandemics showed europe how serious health threats can be to society proactive approaches are needed to ensure that medical countermeasures are available during pandemics proact euresponses overarching objective is to prepare europe for future pandemics by strengthening upon existing networks of experts and civil society focused on clinical therapeutic platform trials within hospital inpatient settings across europe in case of an outbreak this network will provide capacity to pivot rapidly to implement large multicountry platform trials studying therapeutics and diagnostictool performance underpinned by strong community involvement and further strengthened by the inclusion of social and implementation scientists proact euresponse centres on six objectives expand a solid network of clinical centres across europe that will implement a clinical trial assessing a syndromic approach for respiratory viral infections strengthen a laboratory network to identify pathogens and biomarkers of disease monitoring for routine surveillance support a network of methodologists and trialists who will ensure the trials logistical and methodological aspects initiate a network of professionals to work on preparedness tools to ensure a smooth pivot from interpandemic to the pandemic period in case of an outbreak build a network of social science researchers who will provide nuanced understanding of the social contexts and establish a community group to work on activities that will empower patients and citizens in europe regarding their own health and educate them about science and health issues by bringing together scientists social science researchers and civil society members proact euresponse will benefit the entire european population and beyond through decreased mortality and morbidity associated with emerging diseases lower societal economic costs of morbidity strengthened research and innovation expertise human capacities and knowhow for combatting communicable diseases
open science to increase reproducibility in science

embedding reproducibility in the strategy and design of research should be regarded as a key precondition to research quality unfortunately only a fraction of published studies can be reproduced due to eg sciences need to be continuously innovative pressure to publish a lack of transparent reporting and career assessments based on quantity rather than quality while over the past decade many interventions to improve reproducibility have been introduced targeted at funders publishers or individual researchers only few of them have been empirically tested this has resulted in a waste of time effort and resources invested in ineffective or even harmful interventions we need a paradigm and culture shift to reform the ri system both from the top down and the bottom up to regain overall trust in science open science to increase reproducibility in science osiris aims to facilitate this shift by systematically gathering knowledge on the underlying drivers testing effective evidencebased solutions identifying incentives for reproducibility by stakeholders and embedding reproducibility in research design we set out to develop and test new solutions while also testing existing solutions in order to provide guidance on what does and does not workthese aims will be realised by a unique interdisciplinary team of scientists with handson expertise in open science os reproducibility implementation and data sharing along with a range of committed stakeholders including early career researchers publishers and funders that are closely involved in the project through dedicated cocreation activities and as part of our advisory board by the end of the project osiris will deliver and disseminate guidance about evidence based interventions that will improve the reproducibility of science
tackling the cyclacene challenge

cyclacenes ie cyclic versions of acenes consisting of linearly fused benzene rings were first discussed in 1954 by heilbronner but despite considerable synthetic efforts over decades have remained an elusive class of compounds theoretical investigations suggest that cyclacenes are highly reactive due to pronounced polyradical character and significant ring strain all prior attempts to synthesise cyclacenes failed mainly because the final synthetic step of establishing a fully conjugated system was energetically prohibitive despite these challenges cyclacenes remain intriguing synthetic targets because of their unique chemical electronic and structural properties as well as their potential applications in organic optoelectronics or spintronics in this collaborative project we will develop novel synthetic approaches which synergistically combine efficient and highyielding synthetic strategies of belttype precursors that we will transform to cyclacenes by extrusion of suitable leaving groups under cryogenic matrix isolation conditions on surfaces in the solid state and ultimately even in solution our synthetic approach is highly modular and allows to structurally vary the belttype precursors and thus the cyclacenes by placing different substituents at the rims including periannulation or isosteric substitution of ch units by heteroatoms this research combined with stateoftheart computational investigations and characterization even on the singlemolecule level will provide unprecedented insight into the structureproperty relationship of the fully conjugated zigzag topology present in cyclacenes and address fundamental questions of chemical reactivity and the interplay of aromaticity strain and polyradical character this knowledge will finally allow us to synthesise interlocked structures based on cyclacenes and to apply cyclacenes in controlled reactions on surfaces for creating further elusive materials such as polyacenes
the future of earth is possible through collaboration between scientists from different fields

the night4future project aims at showing that the earths future is possible thanks to the constant collaboration of scientists from different fields by implementing researchers night programme we will show that although the climate situation of the earth is very difficult science gives hope for saving it the slogan in science there is hope will be the main motto of the whole event its aim is to make young people see science as a source of strength opportunity and hope for the future during the event we will show how every field of science technical humanities natural health science can be a source of hope to save the planet topics will highlight the importance of the european green deal for europe and its citizens see how the super engineer of the future will be listen to the green alarm for the earth trace trash in space take part in workshops about climate change explore the secrets of biodiversityyou will find out that scientists are ordinary people and their work is really fascinating the night4future project is a continuation of projects from the last fifteen years but it also presents many novelties module researchers at schools preevents and postevents have been prepared enabling researchers and pupils to interact on societal challenges revealing the key role of research in addressing these challenges based on the experience of previous years we are able to modify the program and the way of organizing events in response to the changing situation in the world topics of individual partners have been selected to be consistent with the overall message of the project this years project aims to strengthen the previous ones and shed light on new aspects of science we want to teach young people that the work of scientists brings hope for the planet and it is a lesson worth learning from them we want researchers night 2022 and 2023 to be a great celebration of science promotion of research careers and family fun
6thsense asset valorisation action

6sava or 6thsense asset valorisation action is a strategic coordination support action aimed at propelling the mature outcomes of the h2020 project sixthsense to a wider market sixthsense developed an innovative system for monitoring vital parameters of first responders in extreme environments reaching trl56sava focuses on a streamlined version of sixthsense to drive the commercialization of mature assets in republic of serbia rs croatia hr and bosnia and herzegovi leveraging national and regional funding this initiative empowers core sixthsense partners to capitalize on their results in the regional contextthe project harnesses two distinct assets 1 an industry 40 health monitoring device ensures employee safety in physically demanding manufacturing jobs starting from cement petrochemical and paper industries 2 comprehensive it solution for firefighter operational management with potential for generalisation and application across the civil protection sectorthe primary objective of 6sava is to align technology specifications with the national smart specialization strategies s3 and needs of local industrial actors it will result in crafting highquality applications for nationalregional funding to support advancing these technologies toward market readiness and enhancing technology uptake within the targeted regionsthis will be achieved through workshops to engage stakeholders from the industry national institutions responsible for cohesion policy and funding and technology innovation drivers universities and rto additionally 6sava will drive knowledge transfer and technological adoption in hr rs and ba through targeted activities developed by tecnalia a leading european innovation center 6savas ultimate goal is to amplify the impact of sixthsense innovations creating a positive ripple effect throughout the regions technological landscape
tracing the origin of volatile elements in earth and mars using nucleosynthetic compositions of potassium and zinc in meteorites

the solar system has long been thought to represent the only habitable planetary system the discovery that planets orbiting sunlike stars are common in our galaxy has fostered the concept of planetary habitability which defines the conditions at the surface of a planet required for life to develop including the presence of volatiles energy and organic chemistry elucidating the relationship between the formation pathways of rocky planets and their potential habitability is crucial in that regardone way to approach this is to determine the origin and composition of the building blocks of planets meteorites are witnesses of the earliest stages of planetary accretion and are ideal for this task nucleosynthetic anomalies which are massindependent variations of the isotope composition measured in meteorites provide insights into the building blocks of planets they are robust tracers because they are not affected by geodynamic and chemical differentiation of the planets however the determination of the building blocks of planets necessitates to consider a holistic approach considering constraints from elements with different volatility and cosmochemical behaviour in all extraterrestrial materials for instance nucleosynthetic anomalies of refractory lithophile and siderophile elements do not provide precise constraints on the origin of volatile elements in planetsthe very recent identification of nucleosynthetic anomalies in moderately volatile elements k and zn opens new avenues of research as robust proxies of more volatile elements this project aims at determining the source of the nucleosynthetic anomalies of moderately volatile elements and defining the building blocks of earth and mars building blocks and the source of volatile elements i will use next generation instrumentation combined with emerging technologies to carry out this project
a direct 2 consumer solution for perimenopausal symptom detection

menopause can have extremely negative consequences on the quality of life health work productivity of women due to the symptoms they experience every woman goes through menopause 440m globally but the transition to this point known as perimenopause can last 510 yrs there are up to 35 symptoms of perimenopause that affect women and 75 report moderate tosevere symptoms that interfere with their life 330m women there are no blood tests to diagnose perimenopause and treatment depends on the symptom profile but there are no objective ways to detect the symptoms quantify their frequency severity or track changes in profiles over time clinicians spend most of their time validating the selfreported information from women and of the 60 of women that seek help for their perimenopausal symptoms 70 remain untreated the gap in the market is the availability of objective symptom data that can i provide women with information they need about their perimenopausal symptoms ii be shared with their clinicians to get an earlier and more accurate diagnosis our innovation is a novel firstofitskind product to objectively detect and track menopausal symptoms we have developed a technology enabled ai platform using a biosensor patch that sits under the breast on the lefthand that can detect the frequency severity of perimenopausal symptoms our objectives in line with the expected impact of the women techeu programme are i to build a digital platform allowing us to demonstrate a d2c product for perimenopausal symptom detection ii to use the mentoring training sessions to prepare a market entry strategy for a d2c product iii to derisk private equity investment in a female led femtech company by having a demonstrable product we have an experienced genderbalanced team made up of leading product development clinical software development commercialisation experts with a track record of delivering projects on time and in budget
quantum probes for highpressure superconductivity

materials under high pressure exhibit exciting topics such as the superconductivity sc of hydrogenrich molecular compounds superhydrides in the long standing search of roomtemperature sc while pressures above 100 gpa can be routinely created in a diamond anvil cell dac the tiny sample volume almost precludes the use of nonoptical detection schemes to probe the sample properties the project idea is to integrate nitrogenvacancy nv centers in the dac and use the optically detected magnetic resonance odmr of the nv electronic spin to image the meissner effect the project relies on our first results where we engineered nv centers on the tip of a diamond anvil and adapted quantum sensing methods to detect pressureinduced magnetic and sc transitions under tens of gpa by controlling the stress distribution to achieve hydrostatic conditions that preserve the nv symmetry we have extended this method above 100 gpa reaching the pressure range of existence of sc in superhydrides these materials need to be synthetized at high pressure by laser heating which induces strong inhomogeneities with micron scale we will use of widefield nv magnetometry to locally image the meissner effect and the flux trapping in the sc grains whereas the conventional measurements average over the entire dac geometry and therefore discard all local information by operating nv sensing on a synchrotron beamline we will determine the crystal structure of the superhydrides after the synthesis in the dac we will finally couple the spatial detection with noise spectroscopy to measure the temporal current fluctuations in the sc these methods will be implemented in parallel on hgdoped cuprates as testbed systemsin a complementary task we will investigate the implementation of nvbased microscale nuclear magnetic resonance in the dac our goal will be to exploit the sensitivity of a dense ensemble of nv centers to detect the chemical shift of the nuclear spins in the sample
does intertissue mechanical coupling coordinate neural tube closure

failure of neural tube closure causes neural tube defects ntds which continue to affect 11000 births in europe successful closure requires poorly understood coordination of cellular forcegenerating mechanisms in different embryonic tissues by adopting a novel bioengineering approach i aim to generate the first spatiotemporal map of mechanical forces in neural tube closure this unified biomechanical understanding of morphogenesis will provide a stepchange in our interpretation of geneticteratogenic insults underlying ntdsin this project i will identify the physical forces mediating neural tube closure and describe their intertissue coordination during development this will be based on intravital 3d i3d bioprinting a novel method established by the elvassore group at unipd host this method allows 3d printing of biocompatible force sensors directly inside the neural tube of living chick embryos a wellestablished vertebrate model combined with cutting edge chemical engineering and computational modelling i will investigate the spatiotemporal coordination of mechanical forces and assess whether connected epithelial tissues are mechanically coupled the high positional accuracy of i3d enables previously unfeasible perturbations of morphogenesis to test mechanical coupling between connected epithelia these physical interventions will be paralleled by microfluidic regional delivery of pharmacological inhibitors to biochemically perturb the same morphogenetic processes together these studies will pave the way for the identification of novel preventative and therapeutic strategies to enhance cellular forcegenerating mechanisms during neural tube closure
excellence in humancentered logistics 40

xhulog40 addresses the scope of the widera 2023access 0201 twinning under the priority spreading excellence and widening participation the project establishes cooperation with internationally leading research institutions ntnu tuda and usaar and allows defining strategies for building capabilities and establishing networks that help vilnius gediminas technical university to advance their ri capabilities in humancentered logistics systems of the future xhulog40 the objective of the project entitled xhulog40 excellence in humancentered logistics 40 is to fully realize and further develop the existing scientific potential of the widening partners vilnius tech aiming at scientific excellence in humancentered logistics systems of the future while the focus is on the widening partners the project also enables the other partners to deepen their knowledge in this field and to contribute to the advancement and adoption of xhulog40 results across europe to this purpose xhulog40 intends to increase the research and educational capabilities in humancentered logistics at vilnius tech at the supporting partners establish a longterm knowledge transfer between the contributing parties with a special focus on youngstage researchers encourage the connection among researchers of the partner universities and other leading research institutes and promote networking enable vilnius tech to act as knowledge centres providing modern methodologies logistic tools and solutions in the area of humancentered logistics to transfer knowledge to the widening and associated countries increase the industry and society awareness on humancentered logistics and the value of a close collaboration with academia foster scientific developments through increases in the number of publications patents participation in research programs and new products or services development