Dragon09/odtu_chatbot huggingface dataset:
creating suspects security politics and colonial rule in the spanish empire

suspicio proposes an entirely new hypothesis in the field of modern history as well as in hispanic studies that security became a key concept of governance in the late spanish empire ca17701820 this phenomenon began in the last quarter of 18th century when spain felt the threat of losing its american colonies through external events that questioned the colonial rule including us independence and the influence of the french revolution the perception of threat and the spanish governments distrust of their own population in america gave rise to extensive security regulations and measures in order to protect the colonial order with my extensive expertise in both archive research and hispanic studies suspicio will for the first time study thus far neglected sources of political crime the novel approach to these sources will analyse how the colonial administration identified and judged those individuals who were perceived to be a threat to the order ie who were categorised as suspects there was no longer the requirement for a rebellious act to already have occurred in order to make an individual an enemy of the state but rather the mere suspicion that a person would perhaps in the future act against the state suspicio will study to what extent the creation and persecution of suspects polarised the people so that rather than preserving the colonial rule it had a debilitating effect by regarding the ambivalence and counterproductive effects of security politics the project promises a new interpretation of the dissolution of the spanish empire its case may serve as an example even for today of how supranational political entities can collapse under the pressure of security concerns even though these security measures were meant to preserve them
cognitive robotic tools for humancentered smallscale multirobot operations

robots are still often regarded as large machines with links gears and electric motors autonomously interacting with the surrounding environment despite the great research efforts in robotics and humanrobot interaction hri the way we design use and control robots has not fundamentally changed in the past 20 years we see in smallscale wireless multirobot systems and cognitive hri a revolutionary answer to nowadays robots limitations instead of large tethered machines that are difficult for the human user to control rego proposes an innovative set of aipowered modular microsized swarms of robots they are wirelessly steered by electromagnetic fields as well as able to react to other external stimuli and then naturally controlled by humans through intuitive dexterous interfaces and interaction techniques taking advantage of ai multirobot control strategies these robots can team up and collaborate to fulfill complex tasks in a robust and unprecedented flexible way by exploiting multisensory interaction techniques and cognitive shared control the operator will achieve an unparalleled level of seamless interaction and continuous collaboration with the robotic team according to the application at hand the robotic team will feature different taskspecific characteristics eg biocompatibility for medical procedures biodenitrification for cleaning water ability to carry drugs to fight infections and be dispatched through various delivery systems including a stimuliresponsive milliscale wireless robotic carrier developed within the project to achieve this revolution rego will develop magnetic multirobot motion control systems autonomous swarm control techniques for microsized robots humanrobot hapticcentered interfaces and cognitive sharedcontrol techniques rego enables the next generation of aipowered interactive smallsize multirobots systems with increased capabilities to work with each other and their human operators
restoration of wetlands to minimise emissions and maximise carbon uptake a strategy for long term climate mitigation

the rewet project will facilitate the sustainable restoration and conservation of terrestrial wetlands freshwater wetlands peatlands and floodplains to do so rewet draws upon the network of carefully selected seven demonstrators open labs 2400 ha in total that cover a range of local conditions geographic characteristics governance structures and socialcultural settings to fully understand the wetlandscarbonclimate nexus and provide an replication plan to boost successful wetlands restoration throughout europe and internationally in the open labs the most fitforpurpose technologies will be applied for the monitoring of ghg eddy covariance towers satellite imagery field measurements biodiversity and meteorological events furthermore the social aspect will be analysed by evaluating gender differences locals and key stakeholders acceptance rewet has two additional strong scientific pillars the assessment of eu wetlands status in europe and modelling together with the open labs they will fill out the gaps on wetlands science and provide guidance for costeffective restoration and monitoring practices that are environmentally friendly compatible with the future climate and provide a wide range of ecosystem services as main outcomes rewet will deliver a wetlands inventory with carbon sink potential models for wetlands ghg emissionssequestration under different scenarios including climate change policy recommendations for wetlands restoration sound business models and a roadmap for replication the rewet consortium is a transdisciplinary partnership between researchers industry partners sme nonprofit entities responsible agencies at the local and watershedregional level and one international organisation dedicated to achieving the desired outcomes of the project
longterm joint euau research and innovation partnership on sustainable energy

built on leapre programme implemented between 2020 and 2025 the leapse action will organize 2 cofunded calls steered by european and african funding organisations the calls steering committee csc gathering all funding organisations involved in the action will select the projects to be funded considering the specific national eligibility and funding rules of each funding agency nationality of beneficiaries trl nature of beneficiaries thematic scope etcit should be noted that even if the overall scope of leapse enlarges to all sustainable energy fields matching the ccse scope on energy including the multiannual roadmaps of leapre and the enlarged to green hydrogen issues it will still be possible for funding agencies to focus their specific action on their own priority lines in term of thematic focus or on trl levelleapse draws on the experience and partnership developed in leapre this partnership is further strengthened by a much larger number of african organisationscountries participating to the cofunded calls and by previous collaboration between partners in other projects supporting the euafrica hlpd on sti such as leapagri erafrica leap4fnssa rinea caastnet plus and fosc it will work with other european partnerships such as cetp and dutleapse will also ensure the followup and monitoring of the funded projects the valorisation of the results and clustering activities will ensure a broad dissemination of projects outputs reaching a global coherence among funded projects and avoiding fragmentation the highlevel dialogue foreseen with policymakers and institutional stakeholders will ensure that leapse has access to the relevant instances to raise any policy or regulatory issue hindering the deployment of some innovative solutions
shaping the future from spermatids to spermatozoa

sperm are highly specialised cells whose structure is optimised for a defined function although the distinctive sperm ultrastructure has been known for many years thanks to electron microscopy an understanding of the molecular details of sperm specialisation is severely lagging the gap in our molecular understanding relates to the difficulties in genetically manipulating sperm over the past five years my lab has pioneered the use of cryoelectron tomography to study mature mammalian sperm at the molecular level we developed workflows based on cryofocused ion beam milling and subtomogram averaging that allowed us to provide the first incell structures of mammalian sperm flagella revealing unique microtubule inner proteins we further showed that the sperm centrioles and their surrounding matrix form a dynamic basal complex that facilitates a cascade of internal sliding coupling tail beating with asymmetric head kinking although these findings contribute profoundly to the field the resolution achieved in these studies 20 precluded protein identification in most cases now i plan to develop a workflow based on single particle analysis achieving nearatomic resolution but without purification i will apply this workflow together with biochemical assays and cellular cryoelectron tomography to humans and other species to resolve how germ cells get into shape and acquire motility specifically the mechanisms underlining 1 nuclear shaping 2 centriole remodelling 3 mitochondrial sheath assembly 4 motor apparatus activationunderstanding how male germ cells get into shape is of clinical relevance as sperm morphological defects are often observed in infertility moreover the success rate of assisted reproduction technologies can be improved with better diagnosis and we expect that the new proteins we identify will help this process conversely understanding the acquisition of motility could potentially be used to develop a male contraceptive
a territorial construction system for a circular lowcarbon built environment

globally the construction industry is responsible for over 30 of the extraction of natural resources 25 of solid waste generated and 40 of greenhouse gases ghg emissions around a third of these emissions come from embodied carbon in construction cement and steel are responsible for most of the embodied ghgs representing 80 of the total with recycling of cement and steel having a limited potential for further improving material efficiency the focus is on replacing them with lowcarbon alternatives andor embedding them in reusable construction components reconstruct will i develop lowcarbon alternatives to ordinary portland cement opc to be used in both renovations and new buildings and incorporate construction demolition waste cdw and other waste as much as possible ii manufacture construction components that use such materials and are designed for modularity and dismantling so they can either be reused or easily disassembled and recycled iii embed deconstruction in building design and construct circular lowcarbon buildings that produce nearzero cdw across their lifecycle these objectives will become possible through i the digitization of construction materials products and buildings ii the extensive use of digital tools to support the design construction and deconstruction phases of the circular building and iii the regionalization of the construction value chain through the creation of regional ecosystems of stakeholders covering all the aspects of circular construction the reconstruct concept will be demonstrated by setting up to territorial circular clusters in brussels and barcelona and using reconstructs materials components and innovative tools to design and construct two realscale demonstrator buildings by doing so reconstruct aims to demonstrate its high impact potential including a ghg reduction potential of 13712 mt co2 per year avoidance of 85 million tonnes of cdw per year and substitution of 197 mt of opc concrete per year and its economic feasibility
gant horizon europe gn5ic1

under the new 72month gn5 framework partnership agreement in horizon europe gn5fpa this proposal responds to horizon europe call horizoninfra2021net01sga2 work programme 2122 other actions 2 sga for investments on international connectivity and collaboration received 1 february 2022 gn5ic1 sets out a new plan and implementation for the first phase of a new intercontinental connectivity investment programme meeting the huge growth in network capacity demands and leading the network through a paradigm shift in the digital science and computational infrastructures in the next 10 to 15 years it builds on the successful and relevant experience in planning and procuring and introducing into operation direct intercontinental links such as bella s1 as well as a number of other existing bilateral and reciprocal arrangements for operational links negotiated with other intercontinental partners this project will help ensure sufficient capacity is put in place through procurements and implementations of links during the project term or through setting a roadmap for future investments beyond this timeframethe gant consortium has a long established and successful track record in securing longterm intercontinental network connectivity interconnecting with an increasing number of gateways in the network in coordination with global peers applying proven skills and expertise gant is well placed to maximise the value of the links to be procured with innovative contracts and to secure reciprocal global peering contributions to increase the impact of the resources available in gn5ic1
production of sustainable aviation fuels from waste biomass by coupling of fast pyrolysis with solar energy

the circular fuels project integrates concentrated solar heat solar electrical energy and thermochemical conversion of biobased waste materials to produce sustainable aviation fuels coupling concentrated solar heat with fast pyrolysis to produce sustainable aviation fuels has not yet been achieved and requires technological innovation waste wood ab and agricultural residues straw listed in the renewable energy directive redii annex ix will be used as cheap and abundant biobased waste material feedstocks the feedstock will be first converted into renewable biooil in the new solar assisted fast pyrolysis the use of solar energy removes the need to burn any fraction of the pyrolysis products to heat the pyrolysis process the solar pyrolysis will produce valuable byproducts such as biochar that can improve the economics of the process the pyrolysis oil will be stabilized and upgraded to reduce the oxygen content to close to zero by slurry hydrotreatment and hydrodeoxygenation these processes will employ green hydrogen produced using optimized solar photovoltaicassisted water proton exchange membrane electrolysis finally the oil will be fractionated into sustainable transportation fuels by distillation our main objective is to maximize the fraction of jet fuel in addition we will analyze all component fractions suitable as transportation biofuel products such as gasoline and diesel to maximize the profitability of the concept the proposed new thermal pyrolysis process pathway is not yet standardized for astm d7566 standard specification for aviation turbine fuel containing synthesized hydrocarbons therefore we will perform compatibility and turbine combustion tests for the required standardization and inclusion into astm d7566 we aim for a sustainable aviation fuel production price of 15 kg we will analyze the sustainability aspects of the technology and give policy recommendations for successful commercialization
developing experiencecentric accessible immersive virtual reality technology

accessvr will fill the gap in the scientific knowledge on how people with physical disability particularly people with limited upper and lower body mobility access and experience virtual reality vr technology many of the several million physically disabled people in the eu cannot tap into the huge potential of the technology for leisure education and work vr systems are commonly designed for nondisabled human bodies but as a result of the complexity of vr technology fundamental accessibility barriers for physically disabled users remain unaddressedaccessvr addresses this issue through development of an experiencecentric framework for accessible vr technology the framework will build on technology case studies and a modular vr application that address physical and digital access barriers to vr and will be constructed against disability studies as theoretical backdrop the first phase of the research will examine preferences and needs of disabled people regarding user interfaces and representation of disability in vr through cocreation of individually tailored vr prototypes in a second phase the project will synthesize outcomes into a middleware layer and develop an adaptive vr platform featuring entertainment and workplace scenarios in the third phase the vr platform will be leveraged to evaluate the experience of physically disabled people in vr to refine the framework based on empirical datathe goal of accessvr is to further our understanding of how to create engaging vr experiences for people with physical disability that combine the removal of physical digital and experiential access barriers results are expected to have significant impact on the design of bodycentric technology and the inclusion of physically disabled people ultimately accessvr will enable future research on disability and vr contribute to the accessible design of the technology and lay the foundation for more inclusive technological futures
go to market for the first european itar free modular micro control moment gyroscope actuator enabling 10x more inorbit agility to small satellites ranging from 50kg to 300kg

every day satellites help europe to respond better to new global and societal challenges climate change disaster management security threats migration farming transport or energyto accomplish their mission satellites need actuators to manoeuvre ie change their orientation and point towards the necessary targets on earth eg to collect imagery or simply to communicate our company veoware space has developed an innovative nextgen space actuator technology enabling satellites to manoeuvre 10 times faster to boost their effectiveness our solution is a control moment gyroscope the microcmgveowares technology has been fully tested and qualified on ground but to ensure product viability customer require an inorbit demonstration this project aims at bringing veoware to market with a first flight in orbit and the scaling up of the sales team to prepare serving customer by 2023
a novel firstinitskind aptamerbased lytacs to address the unmet clinical need of diabetic wounds

diabetic foot ulcers dfus a major complication of diabetes occur in 25 of patients with a fiveyear recurrence rate of 65 dfus often end in hospitalization with limb amputations in up to 60 of cases dfu related mortality is 5 within twelve months rising to 42 after five years despite high prevalence and its major impact on the quality of life no effective treatment has been approved so dfu remain a highly unmet clinical conditionaptadegrad aims at obtaining in vivo proofofconcept for a novel firstinclass therapy using aptamerbased lysosome targeted chimeras lytacs to heal diabetic foot ulcers dfus these lytacs will target il1 its receptor il1r1 and mmp9 for degradation proteins known to play a key role in impaired healing in diabetic wounds out hypothesis is that a aptamerbased lytacs moa may offer the potential to deliver a controlled dosedependent reduction of mmp9 il1b and its receptor il1r1 moderating the excessive dfu inflammatory response while maintaining biologically beneficial levels of these proteins to promote healing and prevent infection b the simultaneous targeting of these relevant proteins will produce a synergetic effect in the inflammation cascade providing superior efficacy outcomesshould the main objective of the project is achieved ie show efficacy in animal models of dfu we would be showing for the first time a potential therapy based on lytacs in this case in the context of diabetic ulcers with potential applications in other types of chronic wound or immune pathologies in addition to efficacy data we will be gathering essential knowledge about lytacs toxicity efficacy mechanism of action differences with other approaches such as blocking or inhibition which are essential for successful future translation of the novel concept of lytac in pharmaceutical development to clinical trials
reimagining informality theorizing informal entrepreneurship and economic change in transition era china 1970s1980s

although informality has long been considered a barrier to economic development as more emerging market economies achieve growth even while remaining stubbornly informal this assumption has become a subject of debate recent management scholarship has highlighted the supporting roles that informality plays in economies and the opportunities it provides for marginalized populations yet because of the phenomenological and ahistorical nature of this work the processes by which informality is produced how it evolves over time and how it influences macroeconomic change remain undertheorized in this project i attempt to address these lacunae through a novel historical approach and the analysis of unconventional sources collected from chinese flea markets specifically i apply the tools and frameworks of microhistory to analyze thousands of decommissioned case files of entrepreneurial actors who were prosecuted by chinese state agencies in the 1970s and 1980s through this analysis i aim to 1 map the structure of informal networks of state and nonstate actors and theorize the mechanisms by which they enabled the creative recombination of capital labor and knowledge 2 discover and categorize the collusive practices by which these actors pursued entrepreneurial opportunities circumvented institutional constraints and mitigated risk 3 reveal the entrepreneurial role of local administrators and theorize how their actions reshaped the context in which informal entrepreneurship operated through the fulfillment of these objectives the project seeks to revise existing theories of informality by calling attention to how formalinformal boundaries were contextually and historically contingent and by revealing the bottomup processes through which informal entrepreneurship drives change the project also aims to generate societal and economic impact by developing applied business insights that will inform new entrepreneurial educational initiatives