Dragon09/odtu_chatbot huggingface dataset:
ultrafast optical antiferromagnetic topological spintronics

antiferromagnetic spintronics exploits the antiferromagnetic afm staggered magnetizationnel vector to manipulate spin dependent transport properties in structures containing antiferromagnetic components in atops i plan to use sub 15 fs light pulses to facilitate neel vector reorientation via optically induced neel spin orbit torque in the room temperature dirac nodal line afm material mnpd2 the neel vector reorientation in this material is also associated with changes in fermi surface topology where the orientation of the neel vector controls switching between the degenerate and gapped dirac states mnpd2 with its favourable symmetry to support nel spin orbit torque and the presence of dirac nodal lines in a broad range of energies across the fermi level makes it an ideal candidate for topological afm spintronics applications i will employ optical methods that are interesting in the sense that they can control the magnetization dynamics in ultrashort time scales with high spatial resolution i will use magneto optical mo effects that are quadratic in magnetization and magnetooptical voigt effect move has been proposed to be an effective method to identify the neel vector reorientation in the system pump probe technique will be used to measure the move signal in the fully compensated afm mnpd2 atops will also utilise magnetotransport techniques to characterise the material and verify the magnetic ordering atops plans to establish experimentally that the afm dirac material mnpd2 is an ideal system to realise strong response of magnetotransport and optical properties to the magnetization dynamics near room temperature
multisensor eversion robot towards intelligent endoscopic diagnosis and therapy

colorectal cancer crc represents a significant proportion of malignant diseases interventions are often carried out during the latter stages of development leading to low patient survival rates and poor quality of life in 2022 a european commission report stated that colonoscopybased screening has higher sensitivity than testing for blood in stool but it is less acceptable to participants at the same time effective methods to treat polyps in the colon are limited current approaches are often associated with unsafe oncological margins and high complication rates requiring lifechanging surgeryendotheranostics will usher in a new era for screening colonoscopy advancing the frontiers of medical imaging and robotics a tipgrowing or eversion robot with a sleevelike structure will be created to extend deep into hollow spaces while perceiving the environment through multimodal imaging and sensing it will also act as a conduit to transfer miniaturised instruments to the remote site within the colon for diagnosis and therapy theranostics with these capabilities the system will be able to offer1 painless colon cleansing in preparation for endoscopy2 realtime polyp detection and tissue characterisation through aiassisted multimodal imaging3 effective removal of polyps by conveying a miniature mobile operating chamber equipped with microsurgical tools to the target through the lumen of the eversion robotthe unique technical and clinical challenges will be tackled by the pis each bringing complementary skills backed by their institutions with wide expertise and exceptional facilities the synergy and added value evident in this team will lead to breakthroughs not possible through independent research the outcomes of endotheranostics will revolutionise the theranostics of crc impacting the quality of life of millions of individuals ultimately it will launch a new era for endoluminal intervention with applications beyond medicine
development of a cell immunotherapy targeting nonconventional tumor antigens in ovarian cancer

ovarian cancer represents the most lethal gynecological cancer and one of the deadliest cancers in women globally it affected more than 80 0000 women worldwide in 2022 and killed 207000 the same year 25000 only in europe a womans risk of getting ovarian cancer during her lifetime is about 1 in 78 due to the nonspecific nature of the symptoms it is hard to early detect ovarian cancer and there is currently a lack of effective screening tools for an early diagnosis consequently 75 of patients are diagnosed at an advanced stage leading to poor outcomes and strongly reducing their chances for survival only 3040 five years after diagnosis even though several treatments are currently approved for ovarian cancer they present several limitations and fail to meet the high medical need indeed 23 of patients do not respond to available treatments or relapse after 1st and 2ndline treatmentervaccine aims to provide an innovative solution by developing a new generation of tcrt cell therapy targeting nonconventional antigens with its advanced proprietary bioinformatic platform ervaccine successfully identified antigens derived from human endogenous retroviruses hervs that exhibit abnormal expression exclusively in cancer cells and shared by a high proportion of patients from this work the company developed tcrov1 a tcrtcell therapy with a demonstrated efficacy profile in in vitro and ovarian cancer animal models we expect no major safety concern as we did not observe any toxicity in our preclinical models and based on the specific herv expression in the tumors now ervaccine wants to accelerate the development of its solution by scalingup its smallscale manufacturing process and demonstrating in humans the efficacy and safety of tcrov1 tcrov1 has the potential to be a transformative therapy for ovarian cancer being the first safe and efficient tcrt cell therapy in this indication
disordered metasurfaces with ultimate information capacity for nearinfrared spectroscopy

speckle patterns are distinct features of disordered materials while often regarded as mere noise the intricate and responsive speckle patterns to minor fluctuations in external factors render them an ideal candidate for applications in hyperspectral imaging and sensing the metaspectrometer harnesses the high information capacity of the speckle pattern of resonant disordered metasurfaces for compact machine learningassisted noninvasive and efficient nearinfrared spectroscopy an ultracompact footprint portability costefficiency minimal losses machinelearning assisted recognition angleinsensitivity suppressed specular scatterance significant memory effect and ability to accommodate low coherence fields are the main features that cannot be currently obtained with any technology proposed so far and would represent a huge step forward in the state of the art metaspectrometer brings together the complementary expertise of the postdoctoral researcher pr in metasurface engineering the incoming host cnrsc2n france in silicon photonics optoelectronics and nanofabrication the associated the outgoing host mit usa in spectroscopy and machine learning the secondment host rice usa in lensless imaging and the industrial partner zeiss germany in spectroscopy and market analysis the project allows pr to acquire expertise in silicon photonics technologys design fabrication characterization and commercialization while giving back his expertise in metasurface design the developed nir spectrometers will find direct potential applications in wearable health monitoring systems food screening agriculture and environmental screening that a remarkable global market size the distribution of the work packages with distinct and clearly defined milestones and deliverables makes sure that the progress of the project will be monitored and matched with the work plan
bifoldome homo and heterotypic interactions in assembled foldomes

selfassembly is a fundamental foundation of life but what about coassembly the main goal of bifoldome is to decipher coassembly to understand selfassembly amyloids were assumed to be assembled by one type of protein but our recent elucidation of the first 11 heteroamyloid structure the ripk1ripk3 necrosome core suggests that amyloids composed of two distinct proteins playing key roles in health and disease may be common in fact a viral protein m45 can displace one partner ripk1 to form a distinct 11 heteroamyloid m45ripk3 taking a leaf from the viral playbook this means that for a given selfassembling sequence there may be a mating sequence driving the preferential 11 coassembly of the two thus understanding what drives the preferential formation of coassembled forms over conventional selfassembled species will afford an entirely new vision on assembly processes transversal to all fields of knowledge bifoldome is organized around three different levels of complexity 1 characterizing the formation structure and energetics of representative paradigms of 11 coassembled amyloids using solution and solidstate nmr spectroscopies and energy calculations featuring novel technical innovations that we will develop this will provide the basis for selfassembly by delivering a firm understanding of coassembly 2 applying the fundamental knowledge from 1 to the manipulation of selfassembled diseaseassociated proteins using the powerful concept of 11 coassembly 3 going beyond the state of the art by developing a new methodology to study the assembly of biomolecular condensates the approach which i call optonmr will enable controlled lighttriggered self and coassembly of proteins within the nmr tube opening new avenues to discern between alternative hypotheses for condensate formation and hardening in realtime and at high resolution or for sensitive detection using hyperpolarization schemes
blood and tears the emotional experience of classical greek warfare

blood and tears the emotional experience of classical greek warfare aims to provide the first comprehensive and scientific analysis of the emotional aspects of classical greek military campaigns in the period 490323 bc previous scholarly analyses fail to fully address the issue offering either simplistic and inadequate reconstructions hanson 1989 or seminal contributions on single phenomena regulating the emotional experience in war eg cohesion crowley 2012 social pressure cairns 2019 van wees 2004 this study will fill a considerable gap in the scholarship with a fresh multifaceted approach to the emotional and psychological aspects of greek military campaigns the cultural idiosyncrasies of the greek cultures the interplay of different cultural dynamics and the difference from polis to polis will be acknowledged to reconstruct a culturally appropriate and solid picture the modern notion of morale will be used as a heuristic tool to unravel significant patterns and psychological phenomena hidden in the ancient sources whilst three case studies athens sparta and the ten thousand will frame interpoleis similarities and differences the findings are expected to dramatically advance the promising field of the study of the emotions and psychology of the ancient greeks but also to develop a better appreciation of how ancient intelligentsia conceptualised complex sociopsychological dynamics
technological research action necessary for safe parrtitioning and nuclear transmutation

the impact of low carbon energy sources in combating rapid climate change underlines the role of nuclear energy as part of a sustainable energy mix yet safety and waste concerns must not be downplayed for the latter the main goal should be to recycle used fuel aiming to close the fuel cycle this eases ultimate radioactive waste management enhances proliferation resistance and drastically improves economy and sustainability by better use of fuel resourcesthe snetp deployment plan outlines technical needs for fuel recycling including separation of used fuel fabrication and characterisation of minor actinide bearing fuel and the development of transmutation systems to recover energy and reduce wastethis proposal aligns with the snetp deployment plan and responds to the call in horizoneuratom2023nrt01 topic 05 partitioning and transmutation of minor actinides towards industrial application it focuses on the efficiency of am americium separation from used fuel on experimental and fuel performance code development work studying the behaviour of am bearing fuel under irradiation and on the safety related research supporting the licensing process of myrrha in its role as dedicated accelerator driven transmuter demonstrator this project builds upon the collaborative efforts initiated in the patricia project bringing together communities working on partitioning transmutation and myrrha developmentfinally dedicated work packages deal with education focusing on preand postgraduates and with dissemination targeting the specific stakeholders and the public at large a further task on knowledge management encompasses both foreground data as well as metadata as to ensure that proper quality assessment and validation is possible the project will employ a combination of experiments theoretical studies and numerical simulations harnessing the expertise of 21 research centres and universities from eight eu countries the uk and switzerland an
crmgeothermal raw materials from geothermal fluids occurrence enrichment extraction

geothermal fluids often carry high amounts of elements that the eu considers as critical raw materials crm preliminary calculations show that even a single well has the potential to produce singledigit percentages of the eu needs combined extraction of heat and minerals maximises returns on investment minimises environmental impact requires no additional land use leaves no mining legacies has nearzero carbon footprint and enables domestic supplies of crmto assess overall supply potential crmgeothermal will enlarge an existing geothermal fluid atlas by collecting new data and sampling wells for their crm content in europe and east africa the potential of different geological settings for combined extraction will be evaluatedextractionseparation techniques exist but need to be adapted to the harsh conditions of such systems high temperature pressure and salinities combinations of materials and flowschemes will be assessed at labscale to optimise systems for different geothermal settings and crma modular mobile plant will be developed and deployed at existing geothermal sites to conduct pilot studies investigating upscaling and system integrationthe technological developments will be accompanied by assessments of environmental and social impacts to ensure good governance an unfcunrms compliant reporting template will be developed to create trust among investors regulators and the public the project will advance key reference points for stakeholder engagement in order to obtain and maintain a social license to operatecombined extraction creates new business opportunities for both smes and larger companies and its economics under likely future market developments will be investigated with a view to proposing suitable business modelscrmgeothermal will open up a potentially huge untapped resource and deploy solutions to help europe fulfil the strategic objectives of the eu green deal and the agenda for sustainable development
functionalized graphenes for ink technologies

graderink addresses the pressing need for development of novel inks that can be utilized for inkjet printing of stable selective sensitive and ecofriendly electrodes project aims to deliver the upscaling of an industrially relevant novel manufacturing process for graphenederivative based ink enabling a significant progress in the printing technologies for versatile electrochemical biosensing platform such platform can be utilized for a wide range of medicinally environmentally and foodwatersafety related analytes such as microbes antibiotics pesticides disease markers just to name a fewthe maintenance of a healthy society necessitates not only monitoring human body status but also screening food drinking water air and environment such monitoring requires immediate onsite and easytoread sensing technologies electrochemical biosensors represent an ideal sensing platform because they transduce a specific biochemical event to an electrical signal which can be readily recorded and processed the key component of electrochemical biosensors is the electrode which is used as a solid support for the immobilization of biomolecules and electron movement graphenebased materials are ideally suitable for the construction of electrochemical biosensor electrodes because they offer high surface area unique electrochemical properties and high biocompatibility however graphene itself enables only limited applications and the patterning of graphenebased electrodes remains unsolved challenge digital printing technologies represent a novel strategy for patterning of electrodes their use however requires stable robust and sustainable inks which are not yet commercially availablegraderinks goal will be achieved through the implementation of costeffective materials and processes along with taking trl of the developed technology from 2 to 4 thus shaping a significant business opportunity
jewish women in premodern italy magic medicine and the inquisition

the comprehensive objective of jewit is to provide the first historical reconstruction of jewish womens everyday life and material culture in medieval and early modern italy based on medicomagical traditions related to procreation childbirth and other matters associated with the female body despite recent advances in the study of jewish magic gender and jewishchristian relations integrated indepth research on jewish women through the lens of medicomagical texts and from a perspective which considers local oralaural and crosscultural dynamics of knowledge transmission has been mostly neglected using a sophisticated methodology which integrates for the first time indepth analysis of different types of sources ie jewish and nonjewish manuscripts archival documents material and artistic evidence jewit seeks to a make accessible for the first time in a commented edition a selection of the most relevant manuscript excerpts on jewish childbirth techniques circulated in premodern italy b detect patterns of continuity rupture and change in the dissemination of jewish medicomagical lore related to childbirth during the shift from late antiquity to the medieval era and in the transfer from the east to the west c assess the boundaries between jewish magic and science in medieval and early modern italy d unravel traces of the sense of childbirth as experienced by premodern italian jewish woman that occasionally survive encapsulated in the texts thus contributing to a more inclusive intellectual and cultural history of italian jewry and fostering largescale debates on womens wellbeing diversity and inclusion religious and cultural identity after prestigious postdoctoral positions in israel the us and europe a mscapf at ephe in paris under the guide of nicolas weillparot will allow me to establish my scholarly independence remarkably expanding my career prospects toward a consolidated academic position
euroargo eric scaling up for oneargo network extension

oneargo is the new global fulldepth and multidisciplinary design of the international argo programme the most prominent global in situ ocean observing network oneargo will advance climate change and ocean health research capabilities furthermore by allowing more complete and accurate ocean and climate projections oneargo will strengthen the potential of operational users to deliver services for the monitoring adaptation and mitigation of climate change including at policy level the euroargo one project will allow euroargo eric the legal and organisational framework supporting and coordinating the european contribution to the argo programme to align with the oneargo ambition its overarching objective is scaleup euroargo erics capabilities sustainability and resilience to ensure europes ability to take its share of the global oneargo array implementationto this end the 23 partners of euroargo one willtailor a comprehensive design of oneargo for its european implementationescalate euroargo erics efficacy in delivering oneargo data and servicesaddress the environmental challenges of oneargo operations and engage with the supplier industryimprove oneargo products and services and maximise their impact for operational users and broader scientific communitiesconsolidate euroargo eric leadership and collaborations within the international and european ocean observation landscape anddemonstrate and promote the value of oneargo for societal challengeseuroargo one will considerably accelerate the consolidation of euroargo eric thereby allowing the research infrastructure to deliver on its mission to develop a longterm sustainable european contribution to the oneargo global ocean monitoring system to better understand and predict the ocean its role in the climate system and its health
climate just housing towards more sustainable urban environments for all

climate change is profoundly impacting cities and their inhabitants leading to increased infrastructure failure food and resource shortages and death research has shown that vulnerable households are not only the most exposed to these effects but also experience displacement when cities implement green climateadaptive interventions that change housing markets and their affordability in europe the carbon neutrality goals set by the european green deal will trigger unprecedented transformations that might exacerbate these vulnerabilities in a context where new climateadapted housing is reaching largely middle and highincome groups more research is needed to understand how housing access can be ensured for all residents in green climate adapted cities climatejusthome fills this gap through an innovative mixed methods approach that builds from an indepth understanding of vulnerable households lived experiences and the unique insights they offer to advance just urban climate adaptation housing planning and policymaking using a case study strategy focusing on spains greenest city vitoriagasteiz i will deploy policy analysis spatial analysis ethnography and ethnospatial mapping workshops to generate data housing and climate injustices towards building new theory and knowledge on climate just housingwith the support of my supervisor prof lancione and his cuttingedge european research council erc beyond inhabitation lab at the politecnico di torino as well as the awardwinning basque centre for climate change bc3 the fellowship will train me in ethnography intersectional analysis and ethnospatial mapping and act as a pilot for my own erc starting grant on climate just housing ultimately the project seeks to expand theoretical and practical knowledge about how cities embracing climate change adaptation strategies can develop just housing and urban interventions towards carbon neutrality