Dragon09/odtu_chatbot huggingface dataset:
ibisba delivering the infrastructure as a legal structure

ibisba is a european research infrastructure ri project included on the esfri roadmap its mission is to deliver a range of rd services contributing to the development of industrial biotechnology as a key enabling technology of smart circular economy so far ibisba has benefitted from two horizon 2020 projects one providing preparatory phase funding following on from the preparatory phase which entered its final year in 2023 the ibisbadials project aims to complete preparatory work create and launch ibisba as a european research infrastructure consortiumduring ibisbadials work required to submit compliant statutes will lead to the creation by the european commission of the ibisbaeric legal entity results will ensure that the entity is well structured and sustainable possessing a central hq and solid national nodes located in several eu members states ibisbadials will also confer the future ri with vital tools and procedures securing operational status immediately after its creation moreover the project will provide ibisbaeric with a committed stakeholder base the potential to expand into new european or associate countries and international visibility finally ibisbadials will reinforce ibisbas scientific and technology excellence while embedding its activities in a framework of responsible research and innovation and developing its role as an essential component of education in industrial biotechnologywork in ibisbadials will be performed by a core group of project partners representing the most committed eu member countries however all work will be performed in close cooperation with a wider group of ibisba stakeholders bound by a memorandum of understandingin the mediumterm standpoint ibisbadials will provide the european ri landscape with a new landmark ri that uniquely produces translational research services in the fields of industrial biotechnology thus supporting the development of smart biomanufacturing
a mycorrhizal fungi tunning tool for adaptation to harsh environment

arbuscular mycorrhizal fungi amf are symbiotic fungi that improve plant productivity and plant survival in stress environments amf inocula are produced commercially and used to enhance plant growth and soil quality in agriculture and environmental restoration a system is needed allowing amf inocula to be tailormade providing amf that are adapted or tolerant to given stressful environments at present this does not exist it is also unknown how amf can adapt to a given environment the most advanced amf mass production technique is an in vitro cultivation system however this system has not been developed into a tool allowing the production of amf with a tolerance to a given environment this project provides a novel way to build an invitro amf adaptation tool that will adapt fungi to stress environments and that can then be mass produced for soil remediation increasing anthropogenic activities are the leading causes of soil damage soil is a precious resource and its renewal after contamination is extremely laborious and slow in particular many soils are heavy metal hm polluted we will therefore adapt amf to the most common heavy metal contaminants namely cadmium cd lead pb copper cu and zinc zn this project focuses on adapting the amf species rhizophagus irregularis to hm contamination and understand the adaptation mechanisms at molecular levels the results will not only allow us to fill the scientific gaps regarding amf adaptation to hm environments and whether it is associated with genetic and epigenetic change but also provide a possibility to obtain hm tolerant amf that will be of great environmental and commercial value furthermore this project will immediately allow the possibility of scalingup to mass production moreover the amf adaptation tool will allow further expansion and implementation of this novel technology to other environments for future applications in agriculture and soil remediation
exploring the impact of stellar multiplicity on planet formation across disc evolution

in regions of active star formation the protoplanetary discs around young stars act as planetary factories recent observing campaigns have shown that the majority of protostars belong to multiple stellar systems the younger the stars the higher the degree of multiplicity young discs are then strongly affected by stellar multiplicity unavoidably modifying the way in which planets form the detailed evolution of multiple systems with discs and planets however remains to be explored since most current models have been designed for single stars there is an urgent need to extend these models to multiple stars this will pave the way for a better understanding of the process of planet formation at a more general level the stellarmade project aims to provide a comprehensive view of disc dynamics and planet formation within multiple stellar systems my team and i will thoroughly study multiples to 1 establish the formation channels of protoplanetary discs around young stellar objects 2 follow disc dynamics and grain growth in order to identify the regions of planetesimal formation 3 characterise planetary architectures and the resulting exoplanet population to achieve our goals we will perform hydrodynamical and nbody simulations developing and adapting stateoftheart codes phantom mcfost rebound our calculations will include a broad range of physical processes disc thermodynamics radiative transfer gravitational perturbations aerodynamic friction dust growth and meanmotion resonances this will allow us to identify and quantify stellar multiplicity effects across evolution my previous work on binary stars constitutes proofofconcept that it is possible to coherently connect protoplanetary disc evolution to planetary architectures unveiling the effects of stellar multiplicity on planet formation will be a major breakthrough which will enable us to interpret the whole exoplanetary population under a new and more realistic prism
nanoscale development of plasmonic amplifiers based on 2d materials

the library of 2d materials is growing at a rapid rate driven by the potential extraordinary electronic applications that they can offerin parallel terahertz thz technologies has continued to draw a great interest due to the many applications that it can have aprofound impact in but has continuously been hindered due to the low power and wide scale applicability of current thz sourcetechnologies thz surface plasmonics is coming in to the forefront as an area which can bridge these two emerging technologies andallow the necessary breakthrough that is needed in the so called thz source gap region of 05 3 thz in this project the goal is todevelop architectures which can efficiently amplify thz waves based on surface plasmons in 2d materials the fundamental attributesthat underline this approach resides in the interaction between thz radiation and electrically driven surface plasmons which providesamplification through an exchange of energy and momentum limited only by the properties of the gain medium thus the limits ofthe amplification are governed by limits to the electrical excitation of surface plasmons and how well these surface plasmons coupleto the thz radiation by utilizing novel 2d materials with extraordinary electrical properties based on transition metaldichalcogenides tmds and transition metal monochalcogenides tmms as well as traditional carbon based materials such asgraphene we plan to stretch these limits and achieve ground breaking results in terms of amplification and gain by incorporating thedeveloped amplifiers into existing stateoftheart silicon germanium hetero junction bipolarhbt based thz arrays in the consortium led by thales leading experts from advanced research institutes smes and universitieswhich specialize in growth and modelling of 2d materials as well as thz source development and characterization have cometogether to achieve such a groundbreaking vision
transforming our world collections at the heart of lifelong learning and education

towched will demonstrate transformative potential of inclusive artsbased and heritage collectionsmediated educational interventions for children and youth using sdgs as the results framework these interventions piloted in collaboration between creative and cultural industries ccis collectionsbased organizations cbos and educational institutions across europe will be critically assessedproviding a fieldtested and wellsupported roadmap to enriching our learning ecology with creative use of heritage thus making europe and our world a better place for all our innovative approach relies on the application of the human rightsbased approach hrba as a project planning tool which is foundational in agenda2030 and the sdgs towched will actively engage with children young people educators creatives heritage professionals policymakers and professional development providers to ensure our goals and impacts are not only achieved but that stakeholders can shape these goals in line with the principles of leave noone behind and the right to development furthermore we will focus on lifelong perspectives from early childhood education and care to young adult education in formal and nonformal learning environments we will seek to empower cbos to be more effective in supporting sustainable development through educational activities that foster peoples active free and meaningful participation our transdisciplinary approach will lead to creation of community of practice for competencebased sustainable development education and lifelong learning rooted in our rich european heritage the project will provide practical tools and develop capacities to use these tools in pursuit of these objectives we will work closely with the transdisciplinary new european bauhaus neb and other similar initiatives by integrating our project into this broader european movement we aspire to contribute to the transformation of societies for a sustainable future
syngas modular units providing renewable energy from multiple wastes and for different uses

many eu countries are net importers of oil and gas in 2022 the eus natural gas import dependency rate was 97 and thus particularly exposed to energy reliability and market volatility risk eu natural gas production is continuing its decreasing trend as such the eu agenda ambitious objectives together with the external dependence on natural gas implies that green gases as syngas is essential in the energy transition supremas in this framework is determined to advance the european technology leadership in bioenergy development fostering decentralized gas systems development and contributing to the energy transition for different use cases supremas outcomes will enable circular value chains where multiple residues discarded from different processes will be valorized providing electricity heat and cooling and new materials supremas will develop costeffective modular and movable syngas production units particularly suitable to treat sewage sludge digestate and msw as well as a decision support tool supporting decision making and impact assessment environmental sustainability and technicaleconomic viability of the proposed solutions will be validated through a demonstration campaign in two different eu countries spain and portugal deep replicability assessment will be done and prefeasibility analysis developed in 10 further demosites across all over europe 6 cocreation workshops will be organized to promote stakeholders engagement and communities involvement thus unlocking barriers and make it real supremas replication
pomeranian researchers night european challenges and missions closer to the citizens

pomerania region in northern poland is home to 22 million citizens with its center of socioeconomic gravity concentrated among the seaside metropolitan area tricity it is in this area where one of the largest and most important academic and research hubs in poland is located consisting of many higher education and research institutions including those from top 20 of polish universities it is also a workplace for more than 7000 researchers conducting scientific explorations in almost every field of science pomorska noc naukowcw en pomeranian researchers night prn first organized on 29th september 2023 is success of the grassroots initiative of the pomeranian scientific community this annual event organized on last friday of september is first of such scale within the region and only third one in whole country main goal of prn is to establish a greater impact on the social development of the region by popularizing science bringing scientists closer to the public showing how their work affects our everyday life finally encouraging children and youth to choose a scientific career in the futurewithin the project nightmission we shall develop prn in years 2024 and 2025 by bounding it with researchers at schools initiative the common denominator of activities addressed to the public will be european challenges presented through the prism of the everyday work of scientists in the region the main goal of nightmission is to achieve enhanced engagement of pomerania region citizens with european scale excellent research and research teams within highly inclusive space of researchers night and during researchers at schools initiative project will be implemented via meetings classes workshops and information campaigns and shall consolidate two main messages science is shaping our everyday lives all the time and research is the answer to the challenges of the modern world
3d bioprinting construct for the diminishing of bone tumor and progression of bone tissue regeneration diagnosis of phenotyping in the cellular model and screening as a therapeutic platform

bone tissue engineering has been considered a viable solution bone tissue engineering has been considered a viable solution for clinical restoration and recovery of defected bone tissue caused by injuries skeletal dysfunction and cancer but current approaches are limited in developing cellular disease models to screen the target genes in tumour relapsing which enables finding suitable preclinical strategies animal model the project will use 3d bioprinting to create an external field driving biosensorimpregnated 3d construct as a potential therapeutic platform for screening bone tumour behaviours and multidisciplinary approaches to bone defect recovery hence the main objective is to determine if the formulation of chiromagnetic nanoassembly incorporated electroconductive hydrogel will be able to mimic the in vivo disease model to identify the target of expression in the osteosarcoma model which will enable the finding of an effective therapeutic strategy for osteosarcoma treatment with gender diversity the project will focus on the multidisciplinary approach material science biochemistry and cell biology in the formulation of the multifunctional 3d bioprinting hydrogel visible light based photocrosslinkable the 3d construct will have tunable physical properties such as mechanical stability chiromagnetic etc in determining all stages of cellular behaviour magnetothermal activity in killing tumour cells and electrostimulation mediated osteointegration in tissue regeneration the project will include the transfer of the candidates knowledge to the host and acquiring extensive training from uaveiro on advanced tools and techniques as a part of the career development plan the results will have a potential impact on humankind and patients from all socioeconomical levels and they are in line with the eu mission to have a significant economic impact on the sustainability of public healthcare care for lowto mediumearning patients families
deep spatial proteomics connecting cellular neighbourhoods to functional states

health and disease states result from dynamic cellular interactions within spatially defined regions in tissues and organs in diseases such as cancer these interactions are often disturbed but their systematic analysis with respect to their impact on the proteome a close proxy for cellular function has so far remained elusive to overcome this major bottleneck in molecular biosciences i propose to develop and apply deep spatial proteomics dsp a multimodal strategy which for the first time will link distinct cellular neighbourhoods within biological samples to functional proteome states dsp will combine multiplex immunofluorescence imaging and machinelearning driven cellular neighbourhood profiling with singlecell sensitivity mass spectrometry ms based proteomics our preliminary data support the feasibility and strong potential of dsp to uncover novel disease mechanisms drug targets and predictive biomarkers after development and rigorous benchmarking we will apply dsp to an already available retrospective cohort of advanced head and neck squamous cell carcinoma where response rates for anticancer immunotherapy are only below twenty percent the correlation of cell states and spatial neighbourhoods with clinical outcomes will allow us to identify cell communities of highest likelihood to be critical for treatment response and hence patient survival through their functional characterisation by deep ms based proteomics we will not only gain unique biological insights into immunotherapy resistance and potential therapeutic targets but also identify predictive candidate markers to improve patient stratification this new concept will have strong implications for basic and translational research far beyond the study of cancer immunotherapy dsp could pave the way for a plethora of spatial proteomics applications with countless opportunities for discoverydriven biomedical research
effective field theories to understand and predict the nature of the xyz exotic hadrons

two decades ago the eld of strongly interacting particles entered a golden age with the discovery of exotic hadrons labeled as xyzs the breakthrough fueled a surge in experimental research uncovering dozens of states that appear to lie outside the conventional quark model although some still require experimental conrmation the plethora of new states has sparked intense theoretical investigations into new forms of matter such as quarkgluon hybrids mesonic molecules and tetraquarks making it one of the most signicant open problems in particle physics despite the progress unresolved patterns of masses decays and transitions above openavor thresholds persist and have deepened the mystery surrounding these exotics the intriguing details of production and suppression observed in heavy ion collisions elevated the importance of these studies to probe their naturewith eftxyz i intend to develop for the rst time a comprehensive and unied description of these exotics rooted in quantum eld theory going beyond existing models on the basis of scales separation i construct a general nonrelativistic effective eld theory treatment scale factorization introduces systematicity and simplicity allowing model independent predictions the dynamics contained in the nonperturbative low energy correlators is addressed with new and tailored lattice qcd computational tools by using an open quantum system framework and lattice qcd input the effective eld theory can describe the xyz production in heavy ion collisions eftxyz is poised to make breakthroughs in calculating the properties dynamics and interactions of the xyz in various environments it holds the promise to unravel the nature of these new states having impact on both experiments and our understanding of strongly correlated systems with interdisciplinary implications to other elds eftxyz success is related to the recent advancement in the aforementioned elds in which i played a pivotal role
linksight explainable privacy enhancing technologies

linksight is on a mission to make secure data analytics easy and scalable we enable our customers to create data driven insights out of distributed datasets without sharing any sensitive data how through the magic of advanced cryptography such as mpc and blockchainwe focus on healthcare the eu healthcare system cannot maintain its affordability and accessibility unless new technologies and new ways of working are adopted such as telemedicine and ehealth we need a structured approach to validate which intervention works and which does not to get that answer this requires data sharing between hospitals and insurers how to bring all that data together while complying with the gdprour platform solves this issue we enable hospitals and health insurers to do analytics by themselves and keep control over their own data at all times no need for third parties no need for expensive academic data researchour female ceo and cofounder martine started the first exploration of our solution 4 years ago we cocreated a first product together with healthcare organisations and were the first in nl to perform mpc on real patient data martines contribution lies in setting and expressing the long term vision and goals and to providing structure she makes sure things get done in addition she uses her empathic skills she has a keen eye for everyones needs and makes sure everybody is on board this is especially important as we enable groups of organizations to collaborate on data with this grant we hope to take the next leap and achieve 3 things1 make content so we can explain the possibilities of secure data analytics to a variety of stakeholders from doctors to lawyers to itpeople2 improve the onboarding on our platform so our clients can easily connect to each other and set up a secure data collaborations in just 3 clicks3 improve martines own leadership capabilities by learning from other female founders and be coaching and training
piloting underground storage of heat in geothermal reservoirs

pushit will showcase fullscale application of high temperature heat storage up to 90c in geothermal reservoirs using 3 different technologies at 6 different sites the 3 technologies addressed in pushit are relevant for different reservoir types which are available everywhere in europe in pushit we will develop deploy and test our technologies for a variety of configurations of heat sources heat storage technologies geological conditions distribution systems stakeholder populations and market and legal conditions hence pushit provides a unique scope on demonstration integration and advances for seasonal heat storage that are relevant across europe these results will enhance the utilisation of sustainable energy and create a balanced system for sharing benefits and burdens tied to sustainable heat generation storage and distribution activities we will reduce environmental impact levelised cost of energy and risks and improve performance and robustness via development and demonstration of several enabling technologies ie newly developed monitoring and water quality control and novel drilling and completion and novel control systems societal engagement is a key element and achieved via citizen engagement analysing motivations and perceptions of heat storage and investigating governance policies and business models that engage citizens in decision making regarding urban heating systems including storage the pushit consortium combines heat suppliers well drillers public planning offices and academic partners these cover all required technical and societal knowhow and background for heat systems we will realise operational projects and use these to generate generic solutions and practices relevant across europe all activities will be monitored and reported yielding a valuable comprehensive dataset on the technical and social realworld performance