Dragon09/odtu_chatbot huggingface dataset:
empowering bioeconomy projects by deploying technical business regulatory and social assistance services

bioeconomy projects are crucial for meeting the european green deal and eus 2030 and 2050 climate goals offering sustainable solutions for rural and coastal areas yet the challenge of fragmented funding demands a mechanism to understand existing progress and guide stakeholders towards realising the full bioeconomy potential tobereal is set as a strategic 5year european partnership designed to assist bioeconomy projects across diverse biobased value chains tobereal is committed to adopting a comprehensive strategy to empower the bioeconomy sector it offers specialized expertise and strategic support across four key pillars technical business financial regulatory legal and social innovation this initiative targets all eu regions with a special emphasis on areas where the bioeconomy is less developed ensuring a broad and inclusive approach tobereal leverages an extensive experience and expertise of its consortium including 6 leading bioeconomy clusters 3 recognised technological centres and 4 smes specialised in areas critical for bioeconomy growth such as funding exploitation management and policy development this collective expertise underpins tobereals ambitious goal to foster a multiactor approach facilitating engagement among a wide range of stakeholders by forging connections with related projects and initiatives tobereal aims to deepen the understanding of the bioeconomys challenges and opportunities raising awareness among policymakers businesses sector agencies and investors alike through this effort tobereal seeks to amplify its impact by fostering collaborations across research innovation funding sources and private investments aiming to elevate competitiveness in the biobased and bioeconomy sectors by strategically aligning these elements tobereal compromises to catalyse bioeconomy projects at different levels thereby significantly expanding the scope and influence of eu sustainable bioeconomy ventures
towards a brighter future for the mediterranean with a renewed prima partnership

future4prima will reinforce and enlarge collaborations between ri national funding institutions in the fields of sustainable agrifood systems and water management in the mediterranean as has been done within the horizon 2020 h2020 partnership for research and innovation in the mediterranean area prima establishing a new prima prima2 the project extends prima activities across widening countries and beyond especially towards third countries bordering the mediterranean it will ensure the leveraging of resources pooled towards shared priorities addressing emerging challenges in the region and seeking complementarity with activities and policies with those of the framework programme and relevant european partnerships and eu missions the proposal paves the way for extending the thematic focus of prima to complementary fields only partially targeted in h2020 and horizon europes he current and planned eu partnerships and missions and will add an integrated management approach of resources including ecosystems energy and health to primas original goal of sustainable water management and agrifood systems accelerating the european green deals egd objectives and globally to the un agenda 2030 sustainable development goals sdgs it will also build capacities to stimulate the uptake of ri results aligning this process with real market and social needs the consortium will promote relations among governments enterprises researchers and citizens for ensuring a sound sustainability and longevity well beyond the span of the project
linking the scales towards nonconventional polymer composite structures

the reduction of the environmental footprint of aviation relies on the development and fast deployment of lighter and more efficient polymer composite structures however the current configurations of composite aerospace structures result in a highly constrained design space additionally the limitations of the stateoftheart analysis methods result in overly conservative designs and in timeconsuming certification methodologies as a result composite laminates have only contributed to modest weight savings in aircraft structures based on these observations the main objective of the project is to unleash the full potential of composite systems to yield more efficient aerospace composite structures the premise is that polymer composite laminates are far from being used to their full potential and that significant performance improvements of composite aerospace structures can be obtained by developing a new systemsthinking methodology that will link the different scales of a composite system the methodology relies on the combination of new experimental studies conducted at the microscale of the composite material that will guide the development of analysis methods at different spatial scales the theoretical developments guided by experiments and computations will create the building blocks of a neural network that will unravel the currently hidden relations between manufacturing conditions micro and mesostructures of a composite material and the performance of a composite structure overcoming this knowledge gap will enable the development of new nonconventional microstructures using different types of reinforcing fibres and of new laminate configurations that will not be restrained by a limited set of fibre orientation angles it is expected that for the first time the discontinuity between material design and structural design will be removed opening new avenues for concurrent optimization of composite materials and structures
detoxifying alcohol in the wild investigating convergent evolution among butterflies feeding on fermenting fruits

key innovations allow organisms to exploit novel resources fuelling rapid diversification fermenting fruits have higher nutritional value for example than nectar and their consumption provides higher fitness benefits however the high alcohol concentration in fermenting fruits reaching up to 8 can be detrimental making them a challenging resource nevertheless diverse animals feed and breed on fermenting fruits using the alcohol detoxification system yet little is known about how this convergent phenotype evolved such systems allow addressing key questions at the heart of evolutionary biology what ecological drivers triggered shifts to feeding on fermenting fruits are such shifts key innovations at what level of genetic mechanism do the diverse animals feeding on fermenting fruits show convergence in the alcohol detoxification system these questions can only be answered using a largescale integrative and comparative evolutionary framework yet studies remain focused on within populations of few taxa my proposal seeks to answer these outstanding questions using the rich model system of butterflies to quantify the ecological and genetic mechanisms underlying diet evolution fermenting fruits vs nectar my three main objectives are to 1 unravel the macroevolutionary patterns of convergence in dietary shifts and quantify impacts on diversification 2 conduct a comparative sequence analysis of the alcohol dehydrogenase gene and its enzyme across fruit and nectar feeders and 3 test hypotheses on the effects of dietary alcohol on fitness and gene expression in a fruit and nectar feeder i will integrate information on butterfly natural history with methods from comparative phylogenetics genomics and experimental approaches to achieve my objectives this fellowship will train me in precisely the technical and analytical techniques required for carrying out interdisciplinary research and advancing my career development as a leading scientist
wafer scale dielectrics on twodimensional semiconductors for highperformance field effect transistors

the current semiconductor market dominated by field effect transistors fets is valued at 60740 billion per year projected to reach 98080 billion by 2029 a significant portion of this market involves applications such as in highperformance sensingdetection fets based on atomically thin body atb semiconductors such as molybdenum disulphide mos2 have tremendous potential for ultrasensitive sensors and detectors in the near term fets for these applications can be integrated in back end of the line beol processes where the materials and integration requirements are less stringent compared to fets for processor chips however commercialization of mos2 fets has been slowed by the lack of stable and reproducible device operation that gives rise to poor signal to noise ratios this has led to poor scalability difficulty in achieving consistent electrical characteristics and integration challenges with existing technology which has hindered the widespread adoption of mos2 fets for sensing and detection therefore there is an urgent need to overcome these challenges to realize the full market potential of mos2 fets research supported by the pis erc advanced grant has led to a transformative breakthrough in developing a high quality zirconium dioxide zro2 dielectric that forms an utraclean interface with mos2 so that highly stable and consistent fets can be realised this discovery has demonstrated the feasibility of highperformance reliable mos2 fets with the potential for industrialscale production which has the potential for revolutionise the sensordetection fets market this proof of concept aims to take the necessary commercial and technical steps to bring this innovation to market demonstrate waferscale fabrication of mos2 zro2 fets validate their high performance conduct a critical market assessment to develop a business plan and engage with industry and endusers to establish a clear route to commercialization
my moral and civil commitment giorgio bassanis correspondence with worldwide intellectuals

worldwidebassani project proposes to study and analyze for the first time the extraordinary material represented by the letters exchanged by giorgio bassani with foreign intellectuals between 1948 e 1979 preserved in the giorgio bassani heirs archive in paris thanks to my previous studies on bassanis works the heirs have authorized me to study and publish the correspondence the works of giorgio bassani 19162000 are now considered one of the highest literary reflections on the theme of jewish persecution and the shoah and are read and studied increasingly all over the world writing after the end of second world war in one of the most difficult periods in the history of humanity the author initiates with exceptional anticipation of the times a profound reflection focused not only on the need to bear witness to the atrocities of persecution but also on the duty to refound a society based on peaceful coexistence among bassanis correspondents we find names of important intellectuals of the twentieth century such as cecil roth english historian of jewish origin hans nilssonehle swedish linguist juan rodolfo wilcock argentine scholar francis ponge french poet warren penn robert american writer rolf rheiner german politician and former ss in this dialogue crucial issues are addressed the elaboration of the traumatic past of the shoah but also the crisis and disaster of the old world and the rebirth of a europe of the peoples these documents unpublished and unknown to scholars will offer a new perspective on the evolution of the authors thought and on the international collettive debate on the reelaboration of the tragedy of persecution as well as on the construction of a european cultural identity thanks to the dissemination and exploitation tools provided by the project see 22 this work will offer a new interpretative model to the entire international community of scholars decisionmakers and the broader public
digital technologies for plant health early detection territory surveillance and phytosanitary measures

stella will develop a real time pest surveillance system the system will consist of 3 subsystems 1 an early warning system using novel forecasting models and iot sensors 2 a pest detection system using drones satellites and a smartphone application and 3 a pest response system providing datadriven recommendations for containment and counteractive measures the system will be tested in 6 use case pilots across 5 countries covering 8 various diseases of importance to the eu capacity building activities will be developed with a focus on providing training education and resources to farmers agronomists and other stakeholders involved in crop protection these activities will aim to equip stakeholders with the skills and knowledge necessary to effectively use the stella system and implement environmentally friendly crop protection alternatives policy recommendations generated by the project will aim to support the european commissions goals of reducing pesticide use and managing priority plant pest outbreaks the recommendations will be based on the data and insights gathered through the early warning detection and response system a networking strategy will be developed to leverage existing knowledge and enable links with relevant organisations networks projects and initiatives collaborating with stakeholders as well as other projects will provide opportunities to exchange ideas and learn from others experiences
electrically heated catalytic reforming reactors

process electrification and use of renewable resources for the production of chemicals can have a huge impact on climate change biogas is a particularly attractive renewable carbon source for decentralized production of chemicals due to its huge current production capacity and opportunities for growth in parallel methanol is an important base chemical with a huge and growing market size produced mainly from fossil resources todayin this context eqator aims to demonstrate in an industrially relevant environment trl6 scalable electricallyheated catalytic reactor technologies that will allow conversion of biogas into syngas with improved efficiency compared to the stateofart bridging biogas production with downstream conversion technology into higheradded value products such as methanol fuels and hydrogen the central innovation in eqator is the integrated development of catalysts and reactors and two different yet complementary electric heating technologies resistive and microwave heating leading to disruptive electricallyheated reactor technologies for syngas production eqator will help transform syngas production from largevolume reactors with fired burners to renewable heated and compact reactors up to 90 size reduction of total reactor unit and 5075 reduction in catalyst volume providing significant benefits from process intensification implementation of eqator technology will decrease lifecycle co2 emissions for syngas production by 6080 and save from 7 mt co2year in 2030 up to around 45 mt co2year in 2045the experimental development is supported by a broad integrated sustainability assessment including technoeconomic feasibility environmental footprint and impact on society and rural developmentthe eqator consortium provides complementary world class expertise along the entire value chain and strong industrial commitment to maximise wide exploitation of the results through industrial implementation
visual impairment screening using images from ophthalmology and novel pathways for structural analysis and fast evaluation

clinical eye images could be explored in an entirely new way to provide early detection of serious eye diseases that currently affect thousands worldwide yet could be preventable the objective of visionsafe is to extract macro and microstructure biomarkers from realworld clinical images depicting the retina lens and cornea thereby facilitating early disease detection and personalised management while macrostructural biomarkers related to ocular shape are wellestablished microstructural biomarkers related to tissue remain largely unexplored the projects foundation rests on the preliminary work of the pi which demonstrated the feasibility of deriving diseaserelated microstructure biomarkers from lowresolution clinical eye images the approach combines data science advanced image processing and rigorous experimental validation to better understand the interplay between macro and microstructural biomarkers in prevalent sightthreatening eye diseases including agerelated macular degeneration amd glaucoma cataracts and corneal ectasia using efficient costeffective and accessible tools visionsafe covers several groundbreaking aspects clinical eye data is already available but underused can we use data science for vision preservation the acquisition and combination of macro and microstructural biomarkers from clinical images have not yet been considered is this combination a key for the early diagnosis of eye diseases are we missing out essential information from already available data the projects potential gains are significant it enhances knowledge on eye disease biomarkers accessible through routine eye exams shifts the paradigm toward macro and microstructural biomarker synergy and represents an important step towards a future where eye diseases are identified and managed earlier offering hope and improved quality of life to countless individuals
functional analysis of tspan14 as a genetic risk factor for alzheimers disease

alzheimers disease ad is the most prevalent deadly neurodegenerative disorder for which no effective treatment exists as of today therefore there is an urgent need to better understand the molecular mechanisms behind ad in order to develop more effective treatments against this complex disease recent genetic findings have highlighted several adassociated genes many of which are preferentially expressed in microglia in the brain one of these is tetraspanin 14 tspan14 whose physiological function in the brain is not yet understood recent studies suggest that tspan14 may act as a functional regulator of adam10 a transmembrane protease that cleaves multiple substrates in the brain including the adassociated protein trem2 fulllength trem2 is essential for the phagocytic activity of microglia and its cleavage by adam10 results in loss of function the central aim of the tspan14ad project is to understand how tspan14 controls molecular pathways involved in ad by focusing on proteolysis and function of trem2 specifically we hypothesize that tspan14 increases ad risk by modulation of trem2 cleavage and microglial phagocytosis the 3 objectives of tspan14ad are to 1 determine whether adprotective tspan14 alternative splicing variants result in reduced tspan14 protein expression 2 elucidate whether reduced tspan14 expression results in decreased adam10 cell surface expression 3 assess whether loss of tspan14 reduces trem2 cleavage and enhances phagocytic activity of microglia to accomplish this a combination of biochemical molecular and proteomic techniques will be used within both in vitro and in vivo models including human induced pluripotent stem cell ipscderived microglia and postmortem human brain tissue outcomes of the project have the potential to fill in a large gap in our current understanding of molecular mechanisms leading to ad pathogenesis and may provide insight into novel therapeutic targets for ad and related disorders
advanced simulations in electrocatalysis for efficient production of c3 by carbon dioxide reduction

the climate change has raised concerns about closing the carbon cycle by converting co2 and renewable electricity to chemically stored energy in the form of fuels and commodity chemicals among these longchain hydrocarbons and alcohols are more attractive because of their high energy density and value recently reconstructed oxidederived cu odcu catalysts have shown the potential to produce multicarbon species at lower overpotentials however few simulations have addressed the formation mechanism of these compounds due to the complex dynamics of this system under high currents and the exact site for the excellent odcu catalytic performance remains to be discovered the descriptor project aims to obtain the first generation of co2 electroreduction catalyst with useful faradaic efficiencies towards c3 products by employing computational simulations based on density functional theory dft and augmented by machine learning techniques firstly suitable structures for the odcu materials will be obtained through large scale molecular dynamics simulations based on machine learning potentials by screening the most common ensembles identified via graph theory secondly the mechanism towards c3 will be identified via jdftx scheme and descriptors of activity and selectivity will be found through dimensionality reduction techniques finally to assess and compare to experimental work from our collaborators the contribution of the solventelectrolyte and effect of experimental parameters will be investigated via ab initio molecular dynamics and microkinetic modelling the structures will be characterized via simulations of xray photoelectron spectroscopy and raman spectra etc in summary the outcome of descriptor will have a direct scientific and social impact by increasing the basic knowledge on catalysis of achieving renewable fuel sources and improving eus industrial competitiveness within new technologies for co2 reduction
flavour odour and texture improvements of plantbased dairy products using microbial fermentation products

delicious proposes a novel production technology to create affordable tasty and safe plantbased dairy analogues cheese and kefir with high nutritional value by combining microbial products with plantbased raw materials the project has the ambition to accelerate the dietary shift acting like a paradigm for the whole plantbased food sector delicious contributes to a better nutrition for everybody by developing products with high protein content rich in vitamins fibres and probiotics the project aims also to decrease the environmental footprint of food industry not only by replacing conventional dairy products in peoples diets but also by introducing microbial products which acquire less fresh water less land use and inexpensive residual raw materials having as starting point the perceptions of culinary experts chefs the project will improve the sensory characteristics of the current commercial plantbased products in order to improve their placement in the market to that end we will use tailormade microbial fat produced via precision fermentation yeast biomass and fibreproducing microbial strains to achieve the desired organoleptic properties without additives artificial flavours and avoiding ultraprocessing methodologies to accelerate the commercialisation of the developed products delicious will perform various analyses and evaluations safety assessments nutrition simulations consumers testing and technoeconomic evaluation of the processes combined with behavioural economics to define the profit and price margins for such products capitalising on the great capacity and experience of the consortium on high throughput methodologies the project has also the great ambition to empower fermentation industry with a bioinformatic tool to predict flavour odour and texture of a product based on the initial raw materials and the microorganisms used in fermentation significantly decreasing the costs of product development