Dragon09/odtu_chatbot huggingface dataset:
understanding trajectories of wealth accumulation and their variability

wealthtraject is the first project to comprehensively and systematically examine diversity in longterm trajectories of wealth accumulation within and between social groupswealth inequality is on the rise in many affluent societies it is time to move beyond prevailing static snapshots of average wealth inequality between people to understand this trend instead a dynamic perspective on wealth changes experienced by people over their lifetimes is needed this dynamic perspective reveals how diverse the trajectories of wealth accumulation are ie the degree of trajectory variabilitywealthtraject integrates disconnected strands of literature to study how variability in trajectories emerges over time through the interplay of saving and spending of income receipt of transfers from parents and other family members and deinvestment in unprofitable assetswealthtraject addresses four main innovative objectives i to document variability in wealth trajectories over peoples lives ii to identify intragenerational drivers of variability in wealth trajectories iii to establish the intergenerational relationships between family background and wealth trajectories iv to collect novel life history data on wealth accumulation trajectoriesto address these objectives wealthtraject innovates by adopting a novel approach emphasising the diverse patterns of wealth gains and losses in peoples lives the project challenges the prevalent idea of a uniform humpshaped life cycle accumulation pattern in wealthwealthtraject breaks new ground by combining longitudinal data from surveys and registers and original life history data on wealth that for the first time allow the mapping of wealth trajectories over extended periods of peoples lives advanced quantitative methods are applied to leverage the untapped potential of these datawealthtraject lays the foundations for a new understanding of wealth inequality to inform relevant social policies
linking genome variation with haplotyperesolved sequencing

dna sequencing has transformed biological research and is fast becoming the standardofcare in medicine chances are good that every european person born today may have their genome sequenced at some point in their lifetime it is already happening in iceland the currently prevailing sequencing platform illumina shortread sequencing prioritizes content dna basepairs over preserving longrange haplotype context this decision has paid off so far but comes at the cost of complicated analyses and often lead to undetected diseasecausing chromosome rearrangements alternative longread technologies however have yet to deliver the scale and throughput to truly take over from illumina sequencing to meet the grand challenge of sequencing humanity and biodiversity we need both content and context as part of our erc stg action we have invented haplotagging a technique that restores haplotype context while integrating seamlessly into illumina sequencing we have previously published a smallscale pilot study that haplotagging can deliver superior results at a fraction of existing costs in doing so our team have solved a series of molecular engineering and computational challenges that have stumped far larger parties however our prototype dataset are still not large enough to fully allay concerns from potential licensees regarding robust scalability thus we propose to generate a midscale 2000sample pilot with direct support from illumina to provide additional benchmark data guide scaleup efforts and inform decisionmaking by industry and academic stakeholders we expect this proposal will help transition haplotagging from a research concept towards the market
curvilinear multiferroics

disruptive development of braininspired computing machine learning and deep neural networks for electronic assistants in smartphones autonomous driving systems or chatgpt require new logic and storage concepts which are beyond conventional von neumann computer architectures materials known as multiferroics are identified as key enablers of these technologies in contrast to ferromagnets where the magnetic state is controlled by magnetic fields energy inefficient due to flowing currents magnetoelectric multiferroics allow manipulation of magnetic states by electric fields the great promise of multiferroic materials towards energy efficient computing is compromised by the limited material portfolio literally after decades of research we have only one multiferroic ie bifeo3 potentially promising for room temperature spintronic devices even this most advanced material meets challenges outperforming stateoftheart cmos elementsthe mainstream approach to design magnetoelectrics is to induce ferroelectric ordering in magnets to control nonvolatile magnetic states electrically although intuitively understandable this concept failed providing a technologicallyrelevant multiferroics here we propose a paradigm shift in the design of multiferroic materials instead of trying to induce ferroelectricity we will realize curvilinear multiferroics by imposing ferrotoroidal order in geometrically curved magnetic thin filmsfundamentally we predict that effects of geometric curvature and inhomogeneous mechanical strain will induce sizeable ferrotoroidal order parameter in any magnetically ordered material rendering this material multiferroic hence curvilinear systems will turn rare ferrotoroidic materials in a broadly populated material class available for material science and technologies similar to the conventional ferromagnetsthis project will enable curvilinear multiferroics and validate their application potential for memory and logic devices
letting up senescence and inflammaging through t cells

with the increase in human life expectancy there is an urgent need to understand the common molecular pathways by which aging results in a progressively higher susceptibility to chronic morbidity disability and frailty in the last years immunometabolism has emerged as a new field to boost immune responses for cancer immunotherapies as well as to dampen autoimmune diseases a recent discovery from my lab has revealed the critical role of t cell metabolism in accelerating the onset of ageassociated diseases and multimorbidity this finding has opened a new path to investigate the diverse t cell intrinsic and external stimuli that instruct t cell differentiation towards a dysfunctional state during aging with the final goal of designing effective strategies to promote healthy aging lettbe will address the hypothesis that the timedependent deterioration of t lymphocytes contributes not only to immunosenescence but also to the general aging process the lettbe project proposes to use multidisciplinary approaches to target ageassociated t cells for preventing inflammaging senescence and ageassociated multimorbidity our central goals are 1 to define ageassociated t cells heterogeneity with special focus in their cellular origin clonality metabolic vulnerabilities and transcriptomic signatures 2 to decode the environmental signals that are imprinted on ageassociated t cells and contribute to their development 3 to identify new strategies to targeting ageassociated t cells for slowing down immunosenescence and for boosting resilience to inflammaging systemic senescence and agerelated multimorbidity in sum lettbe puts forward an ambitious but feasible program with the wide purpose of understanding the specific molecular mechanisms and metabolic requirements of ageassociated t cells with the final goal to guide new strategies to improve healthy aging
religion and comics new forms of mediation of religion

religiomics aims at capturing new forms of religion and spirituality represented and experienced in comics by both artists and audiences considering the growth of comics production and consumption this project is crucial to understand the transformations of religious phenomena in western societies and their connections with popular culture religiomics investigates the relationship between comics and religion by studying 1 the artists subjectivities and biographical paths 2 the intertwined influences between the artistic production and religion 3 audiences receptions and 4 the transformation of the comics field religiomics proposes a crossnational comparative perspective focusing on artists and audiences with different religious and cultural backgrounds in europe and the usa it is innovative in considering comics as a medium for religious expression and not only as an instrument of commodification and banalisation of religion it is multidisciplinary as it combines and connects sociology of religion comics studies media studies and sociology of art the fellow will be hosted at the university of lausanne outgoing associated partner the university of harvard secondment and the university of bologna host institution the fellow an expert in sociology of religion will gain the expertise to carry out the research in lausanne on the relationship between contemporary art and religion at harvard on comics studies and spirituality and pop culture and in bologna on sociology of art and discourse analysis religiomics will address the following questions rq1 how do comics artists live and represent religion and spirituality rq2 how does the comics medium shape and how is it shaped by religion and spirituality rq3 how are religious narratives and symbols experienced by the audiences of comics rq4 how did religion favour the emergence of the semiautonomous artistic field of highbrow comics in tension with commercial comics
establishing museomics as a tool to inform the conservation of endangered species

global biodiversity is being decimated by human activities including agriculture deforestation and land use change this is causing unprecedented population declines and pushing species to extinction especially in tropical ecosystems genetic health is an important measure of population viability and to help identify populations at risk this is now being included in conservation programs however incorporating this level of information on genetic diversity can be challenging additionally because standing levels of variation differ between species this makes assessing whether a population has low or high genetic diversity can be very difficult in response museomic will harness new ancient genetic and museomics techniques sequencing of museum specimens to measure changes in genetic diversity in three extremely vulnerable mammals anoa babirusa and sulawesi warty pig in the biodiversity hotspot of wallacea as an isolated tropical archipelago in indonesia wallacea is the perfect natural laboratory for understanding how ancient and anthropogenic disturbances have impacted the genetic erosion of the three flagship mammals and is contributing to their decline by tracking changes in genetic health through time and space museomic will gain insights into the extinction risk these unique taxa face and will directly benefit population management and longterm survival by identifying unique genetic diversity designating conservation units and making captive breeding recommendations hosted by prof l frantz at ludwig maximilian university munich lmu through museomic dr rosie drinkwater will gain new skills in bioinformatics and population genetics grow her research network and succeed as a future leader in conservation biology
foralien towards the development of a foraminiferal nonindigenous species index

foralien foraminifera alien is a project aiming to fill the lack of knowledge of nonindigenous ie alien benthic foraminifera marine protists observed recently in europe to make them a reliable indicator of human impacts for a better integration into biomonitoring surveys in the context of the european regulation of the marine framework strategy directive to do so i plan to sample surface sediment and sediment cores of several sites on the west swedish coast which are composed of understudied harbours in terms of foraminifera but known places of pollution and introduction and fjords where some have been recently observed such astrochammina hadai and nonionella sp t1 among those nis ammonia confertitesta could also occur there this species has been recently identified as a pseudocryptic species included in the ammonia tepida morphotype with two other very morphologically similar species a aberdoveyensis and a veneta that are native species in europe in a first place i will morphologically identify these nis by defining easy criteria of identification and apply a recently developped method allowing an easy identification of the three species of the a tepida morphotype to complement the morphological method i will apply novel methods genetic digital polymerase chain reaction and deep learning models to identify nis foraminifera quickly and reliably assess their efficiency in biomonitoring surveys secondly i will use methods precedingly described and sediment samples to analyse the spatiotemporal distribution and time of arrival of nis in the region this would result in the development of a nis index to asses their impact on native species finally environmental parameters will be measured to define the unknown ecological requirements of nis to better integrate them in traditional foraminiferal biotic indices used to assess the health of ecosystems and to explain and forecast their possible succesful invasions in sweden
migration trajectories natural experiments and effects of smallarea contexts on health a privacypreserving linkage study of routine and primary data among resettlement refugees

the health effects of the migration trajectory from pre to postmigration in new environments have yet been poorly studied methodological challenges and selection effects limit the possibilities for causal inferences on how differences in social economic or political factors at smallarea level affect variation in health among migrants eg differential mortality or selfreported health knowledge about such relations would not only inform better and health and integration policies for migrants considering migrants as humans in new environments not as singularity may allow to conclude on the relationship between context and health more general and inform public health beyond immigration however randomisation of individuals into new contexts is not possible and establishment of prospective cohorts from pre to postmigration settings is challenging resourceintensive and prone to selection bias the aim of intersect is to study human mobility and health consequences of different social economic and policy environments at smallarea level to this end intersect builds on three innovations i it reconstructs the migration trajectory by using existing data among germanbound resettlement refugees through datalinkage or distributed computation techniques ii it capitalises on mandatory dispersal as natural experiment to minimise selective migration into contexts iii it prospectively collects primary data on health of resettlement refugees and combines these with administrative and contextual data using these methodological innovations intersect creates a unique research infrastructure that allows answering important research questions on social economic and political factors at smallarea level which causally explain a mortality differences among refugees while considering baseline health status b changes in selfreported health status depending on changes in contexts and c individual andor contextual factors moderating such effects
small modular reactor for a european safe and decarbonized energy mix

small modular reactors smrs can be hybridized with other energy sources storage systems and energy conversion applications to provide electricity heat and hydrogen smr technology thus has the potential to strongly contribute to the energy decarbonisation in order to achieve climateneutrality in europe by 2050 however the integration of nuclear reactors particularly smrs in hybrid energy systems is a new rd topic to be investigated in this context the tandem project aims to provide assessments and tools to facilitate the safe secure and efficient integration of smrs into smart lowcarbon hybrid energy systems it proposes to specifically address the safety issues of smrs related to their integration into hybrid energy systems involving specific interactions between smrs and the rest of the hybrid systems
high performance power electronics integrations

hipe brings together 13 participants covering the whole value chain to develop a new highly energyefficient costeffective modular compact and integrated wide bandgap wbg power electronics solutions for the next generation of battery electric vehicles bev and to facilitate a significant market penetration of wbg in the automotive sectorthe project outputs will include i a scalable and modular family of wbgbased traction inverters and dcdc converters with significantly improved specific cooling performance suitable for 400v 800v and 1200v applications with power ratings from 50 to 250 kw integrated into electric drives enabling drastic size and weight reductions ii a family of integrated wbgbased onboard chargers and dcdc converters with optimised innovative topologies including use of gan and iii integrated faulttolerant and costeffective ganbased power electronics for highvoltage ancillaries and chassis actuators the result will be an unprecedented level of functional integration eg the hipe power electronics solutions will be smart cyberphysical systems incl intelligent and predictive controllers to optimise performance innovative and computationally efficient datadriven approaches to monitor the stateofhealth of the relevant hardware as well as novel digitaltwinbased methodologies to tailor the component and vehiclelevel algorithms to the specific condition of the hardware installed on each individual bev and actively control the reliability and availability of the relevant parts this will be achieved while preserving the expected automotive quality level without having to recur to overengineering thanks to the innovative implementation of datadriven dependability techniques for cyberphysical systems the extensive simulation analyses running in parallel with the design and experimental activities will further demonstrate the scalability modularity and wider potential impact of power electronics solutions
nanotribology studies of friction and osteointegration at the nanoscale and its relationship with interfaces

nanotriosteo is a scientific cooperation project based on experimental and theoretical research of the surface iteractions on solid materials at nanoscale for improving materials for engineering applications nanotriosteo will provide theoretical support for better understanding of process at the nanotribo interface developing models based on experimental information that provide feedback to materials design nanotriosteo will develop capacities for the study at the level of the density functional theory and molecular dynamics of molecular aspects of nanotribology and oesteointegration phenomena in materials used for surgical replacement of hip and knee with an endoprosthesis modern materials science and in particular surface science is all about the molecular level knowledge of physical chemical and biological processes occurring in the nanometer scale vicinity of surfaces or interfaces nanotriosteo will apply computer simulations methods that allow complementing experimental studies and interpreting at atomic scale the lubrication properties of different carbon nanostructures sicxsteel and ti oxides interfaces nanotribology is a key in understanding the first events of friction wear and adhesion behaviours at solidsolid and solidliquid interfaces of materials in relative motion an exceptional expertise in theoretical physics and chemistry and simulations is an added value for understanding process at molecular level nanotriosteo activities are linked to research as well as to education both of them will empower the cooperation among the partners involved this project will allow the start of networking among the four participants this cooperation will be strengthened due to the secondments that will be carried out during nanotriosteo furthermore this project will be the foundation for future cooperation among the partners due to their interdisciplinary expertise and the synergetic approach to be used within this project
bringing closer research to all creating drive for studying stem areas and chosing a science carrier

research2all aims to bring closer researchers career to the general public focusing on young people by allowing a deep understanding of research and innovation by organising interactive programmes and communication activities research2all aims at creating environmental consciousness in society showing the key role of research and innovation in addressing local and global societal challenges and so their essential part of our everyday lifethrough raising awareness of circular economy processes the project will contribute to the objectives of european green deal and the call of msca and citizens 2023 bay zoltn nonprofit ltd for applied research and hungarian association of environmental enterprises will use their wide range of experiences in scientific communication to attract the most possible participants pupils students teachers adults families researchers experts and professionalsduring the research2all programmes researchers innovators scientists eg msca grant holders will be involved with a special attention to female participants and researchers the project will cover 3 big cities in hungary with 35004000 visitors in the nights where next to green topics eg eucorner green deal aims and their achievement raw materials circular economy smart solutions emobility research careers all separate venues will develop a lot of programmes introducing their professional specialization themes in research researchers at school will include a scientific roadshow throughout the country visiting schools of smaller settlements supplemented with a nationwide scientific award competitionthrough its awareness raising campaign research2all delivers the main message of ern to as many members of society as possible with offering interactive social events eg science cafs round table discussions with professionals and with use of modern communication tools streaming social media podcasts etc and a strong media campaign