Dragon09/odtu_chatbot huggingface dataset:
development of ultra speed resilient costeffective lifibased free space optical communication to connect hospitals departments clinics and home care patients for next generation hospitals

the development of highspeed communication requirements due to explosive growth of subscribers each year has directed researchers to plan the next generation communication systems that can manage the current growing demand the millimeter microwaves waves which function within 30 ghz to 300 ghz can become prospective carriers for delivering large amounts of data but in hospital setups these radio waves are exposed to strict guidelines due to their direct impact on patients health as well as high interference with other medical equipment which again imposes severe challenges for patients the free space optical system might become an attractive solution to transmit medical data over light waves as a carrier lifi light fidelity is a bidirectional wireless system that transmits data via leds or infrared light leds are much cheaper than laser making the fso link costeffective lifi does not interfere with the hospital equipment that relies on radio waves lifi is one of the future wireless communication technologies which will help to develop nextgeneration hospitals with ultrahighspeed transmission the overall objective of this research proposal is the development of ultra speed resilient costeffective lifi based free space optical communication to connect hospitals departments clinics and home care patients for next generation hospitals however fading due to atmospheric turbulence is the main problem affecting the fso communication system performance therefore a case study on how the atmosphere around malta affects light transmission in free space will be carried out to take measures to improve connectivity after that the researcher will analyses developed fso link performance on the ground considering different weather conditionsfog haze rain of malta and internal system parameters transmitter divergence angle receiver aperture diameter and link range on data rate power received and snr
temporally complex odour information encoding

a fundamental challenge for the brain is to extract relevant information from an ever changing external world natural odours are in a constant state of flux turbulent airflow shapes odours into spatiotemporally complex plumes that carry information about the olfactory scenery and provide vital clues about the location of for example food sources or predators how the mammalian olfactory system extracts information about space from temporal odour dynamics however is still not well understoodrecent methodological advances in presenting dynamic odour stimuli neural activity recordings and machinevision algorithms now offer the exciting opportunity to address this fundamental question using a multidisciplinary approach this project will uncover how temporally complex odour information is processed across the olfactory system and how odour dynamics give rise to behaviourwe will first investigate how temporally complex odour information is represented across key structures of the mammalian olfactory system using in vivo physiology this will provide important groundwork for the next step elucidating the cellular and circuit mechanisms underlying the encoding of dynamic odours in the early olfactory system finally we will study which features of temporally complex odours are used for navigation behaviour by simultaneously recording and correlating the animals respiration sampling strategy the dynamic odour profile encountered by the animal and neural activity from early and higher order olfactory areas in freely moving miceby combining cellular and systems neuroscience with behavioural investigations we aim to directly assess how mammals use olfaction to extract information about space from time i strongly believe that this innovative research programme will generate novel and highly generalizable insights into how naturalistic sensory information is processed and that it will uncover neural mechanisms that give rise to our perception of the world
next generation inblood glucose monitoring using noninvasive optoacoustic sensing

glumon aims to leverage a new class of a biomedical optoacoustic sensor developed under the fetopen project rsense ga 862811 and offer the next generation of noninvasive biochemical invivo sensing the preliminary sensor for noninvasive inblood glucose sensing has already produced outstanding findings and places the technology well ahead of its competition addressing the limitations of existing sensors mainly accurate noninvasive continuous monitoring of bloodglucose as well as comfort the glumon sensor will better address diabetes healthcare needs as a secondary goal and contingency plan glumon will exploit this technology as a lipid sensor and build further potential by addressing the emerging precision nutrition marketthe objectives of the glumon project are to1 mature the technology from a lab benchtop setup to a functional portable sensor prototype
creation of innovative humidity to electricity renewable energy conversion technology towards sustainable energy challenge

catcher project is aimed at development of innovative technology to exploit the atmospheric humidity for direct conversion to the electricity thus gain a new sustainable source of renewable energy and to contribute to implementing the specific priorities for strengthening the eu leadership on renewablesthe successful realization of the project is assured by implementation of knowledge sharing in material science physics nanoelectronics green chemistry nanoengineering sustainability and research marketing via international and intersectorial collaboration of highly qualified research and business from portugal belgium austria spain poland and ukraineup to date we developed the theoretical basis for the humidity to electricity conversion mechanism delivered proof of the concept and elaborated the firstgeneration converter prototype advanced humidity to electricity converter within accomplished 20162019 h2020mscarise2015 hunter project attested and further patented pctua2019000147 in 2020 project is targeted on advancement optimization and scalability of a previously developed technology that converts atmospheric humidity into electrical current up to date value of 36 mwg or 182 mwcm2 with an expected output power density of 36 mwg or 15 20 mwcm2 which will be ready for scaling up thus could be prepared for further integration with existed eu electrical system for general energy usethe proposed solution is expected to contribute to implementing the specific priorities for strengthening the eu leadership on renewables laid out in the communication for accelerating clean energy innovation sharing the culture of research and innovation the catcher project will allow applying recent advancements in nanotechnology science and engineering to address directive eu 20182001 on the promotion of the use of energy from renewable sources eu strategic energy technology plan set plan and eu rethinking 2050 strategy
reproductive anthropometric and disease traits integrated coevolutionary analysis of life history tradeoffs

life history theory lht provides fundamental means to understanding adaptive evolution across the animal kingdom including in our own lineage although observational studies have found plenty of support for the predictions of lht in human populations connecting traits such as birthweight and adult body size to age of menarche and menopause as well as disease risk the fundamental biological mechanisms linking many of these traits are poorly understood here i propose for the first time to bring together matching genotype and phenotype data from two large national biobanks and state of the art statistical tools and genetic databases to formally investigate the extent to which the observational links between reproductive and anthropometric traits can be explained by pleiotropy andor shared genetic pathways as well as the extent to which these pathways have been subject to natural selection over the past 10000 years the proposed interdisciplinary project carried out at the institute of genomics at university of tartu igut will enable me to learn advanced techniques in association mapping as well as management of a project involving biobank and other clinical data under the supervision of experienced researchers at statistical and medical genomics as such the project provides an outstanding launchpad for the next stage in my research career at the intersection of evolutionary and medical genomics as an independent group leader
pushing the limits of largescale energy storage optimized combined cycle caes

pushccc proposes to solve the key existing limits of compressed air energy storage caes scalability replicability efficiency and energy density while boosting its costeffective commercial development in europe by bringing a breakthrough caes concept to trl4 which is based on a novel optimized integration of advanced technology and scientific advances beyond the state of the art pushing the efficiency and profitability of the volatilefluidbased isobaric adiabatic combined cycle caes ccc patented by riegosur a scientifically proven highpotential concept due to the enhancement of turbomachinery efficiency and cavern volume minimization the construction of an experimental cavern lab in the canary islands will lead to the first isobaric adiabatic caes system at trl4 in europe while meeting the expected outcomes of the challenge filling in the existing gaps to accelerate the penetration of renewable energies in the gridpushccc brings together expert partners to solve the key scaling efficiency and profitability issues by leveraging an aibased optimized heat pump cycle to minimize the energy requirements of the volatile fluid processes in realtime considering climatological conditions i a costeffective largescale membrane for suitable operation in the hardrock cavern ii optimized turbomachinery for aacaes applications singlestage compressor iii a costeffective efficient heat storage technology based on innovative heat exchangers and heat storage medium iv a disruptive aibased hierarchical control system v bringing a highefficient 80 costeffective technology with high replication potential high energy density 118 kwhm3 allows hard rock areas which are a major part of the continental landuse autonomous plants will operate with atmospheric air and closed loop water co2 which will be captured 10 ktn of co2 per year for a standard 500 mw plant from the overloaded atmosphere with an innovative system
einstein gravity and nonlinear waves physical models numerical simulations and data analysis

the study of nonlinear waves on curved geometries have been increasingly important in physics and engineering for example to model and built more efficient and environmentally friendly materials the difficulty in dealing with those wave equations including the einstein equations led to impressive recent developments of geometry and analysis as well as powerful numerical methods requiring the highest computer power in turn the recent observations of the most challenging wave signals such as gravitational waves ignited unprecedented investment on experiments and data analysis the einsteinwaves network will allow interdisciplinary mobility and training of researchers in the new methods and techniques that will make possible previously intractable analysis relevant to current and nearfuture developments of computational methods and experiments gathering an unprecedented team of top researchers in mathematics theoretical physics and computation we intend to employ our expertise to provide a unique opportunity for new career development perspectives the activities will include network courses workshops and engagement with active cuttingedge research einsteinwaves is set up to integrate several existing and highly recognized annual conferences with a series of new schools and workshops including nonacademic participants through developing invaluable analytic computational and soft skills researchers will develop the potential to become the next generation of european leaders in academia industry and the public sector finally the training we offer and the research carried out will be made open and available boosting europes leadership in fields of analysis mathematical physics and computational methods
unravelling signalling heterogeneity using deep learning and mechanistic modelling

signalling enables cells to respond to external cues but the inherent heterogeneity of individual cell responsesessential for multicellular organization complicates disease treatment heterogeneity arises from drivers atsystem and molecular scales intertwined through feedback loops making quantitative understanding andprediction challenging i will address this by pioneering transformative computational methods that predictphosphosignalling responses by integrating deep learning with mechanistic modelling to integratesystems and molecular scalesby using unbiased pattern recognition of deep learning models i will learn cell states and simplephosphorylation rate laws these will be combined with mechanistic models integrating biologicalknowledge to build simple and interpretable models that predict signalling responses from baseline omicsprofiles across distinct timeresolved and perturbational conditions i will apply these methods to investigatedrivers of heterogeneity in receptor tyrosine kinase rtk and rat sarcoma ras signalling in response togrowth factors and targeted inhibitors in cancer cell lines i will validate the approach by reprogrammingpatientderived organoids using modelproposed inhibitor combinationsthe proposed research will advance our fundamental understanding of signalling regulation and coregulationwith cellular states given the vital role of rtk and ras signalling in human health it also holds the potentialfor translational impact more broadly the proposed computational methods are versatile and could be appliedto a broad range of biological and nonbiological systems
liwefor living labs for wetland forest research

the main aim of the liwefor is to establish and develop a global network of living labs of wetland forest research education and management the project team consists of the university of helsinki and karlsruhe institute of technology as topclass research counterparts and the university of tartu as the recipient as a driving vehicle of the project four joint field campaigns to global greenhouse gas emission hotspots in tropical wetland forest regions peru and malaysia will enforce educational knowledge transfer in addition to training this exploratory research component binds together other activities from all partners it will also serve as a proofofconcept for testing the virtual framework of lls that will enable hybrid formats of skills transfer teaching and training on remote liwefor a research and education project addresses the need to systematically raise the level of expertise among researchers and decisionmakers in the widening country of estonia the twinning partnership project will bring expertise from countries with toplevel forest ecosystem research germany and finland particularly focusing on enhancing career awareness enabling a capable workforce and on promoting sciencerelated careers the major outcome will be a network of living labs of wetland forest research and education a major focus is put on 1 closing the knowledge and experience gap between the donor and recipient partners 2 building carbon and nutrient management strategies for temperate and tropical wetland forests involving stakeholders and policymakers 3 creating an open data repository of ghg measurements and environmental factors in wetland forests 4 constructing a basis for global spread of the living labs network of wetland forest research and education
transitions to adulthood in a context of migration from unaccompanied minors in scandinavia to refuge seeking young adults in france

discussions about migration integration and unaccompanied minors figure prominently across europe in public discourse and at policy level thousands of unaccompanied minors arrive in europe each year many are granted temporary or permanent permission to stay yet little research has focused on their transitions to adulthood comages scientific significance lies in its aim to contribute to address this gap through investigating unaccompanied minors social and legal transitions to adulthood as affected by structural implications imaginaries and relational aspects this is of relevance to support further research on the topic and for european policymakers and practitioners to respond to the needs and situations unaccompanied minors experience upon their arrival and stay young afghans are a timely and relevant case study to investigate transitions to adulthood as they are the largest group of unaccompanied minors claiming asylum in europe each year since 2008 to investigate transitions as affected by the return turn ie increased use of temporary protection and focus on return participants will be recruited among young afghans who arrived in scandinavia as minors and left for france to avoid forced removal as they approach legal adulthood comage is an ethnographic study drawing on indepth interviews participantobservation and creative coarticulations as a bottomup approach that tunes into different forms layers and modes of expression comage builds on the experienced researchers previous research on young afghans journeys to europe and the implications of age and social relations on their trajectories
crosssectoral alliance as the key for innovationdriven business success of estonian and greek reproductive healthcare

constantly decreasing infertility rates and low success rates of in vitro fertilization ivf associated with the advanced age of couples create challenges in reproductive medicine it is crucial to fill the existing gaps to unlock the socioeconomic benefits and boost the commercial viability of reproductive medicine in europe the gap in access to excellence is especially witnessed in widening countries such as greece and estonia where the academic sector is lagging behind producing a low volume of commercialised innovations and lowquality clinical services it poses obstacles in creating competitive positions for highly talented specialists with career perspectives and a strong interest in boosting local reproductive medicine stimulating the brain drain and minimizing lifelong learning opportunities the contribution of the nestor project to solving these challenges is aimed at improving the research and innovation performance of institutions involved in reproductive medicine by boosting the collaboration between industry and academia in widening and nonwidening countries through crosssectoral and international mobilities the nestor consortium consists of 8 partners from academic and industry partners from the netherlands greece and estonia ensuring the knowledge transfer and advancement in four key reproductive medicine modalities for the reproductively aged population personalised medicine solutions ivf embryo and uterine health studies and novel noninvasive prenatal testing technologiesin total nestor will engage 23 era talents from the widening countries boosting their research skills nurturing their innovative and entrepreneurial mindset and providing them with other transferable skills the welltailored secondment methodology is aimed at raising their research profiles improving their career perspectives and opportunities for lifelong learning which will help reverse the brain drain in the long term
plasma medicine against actinic keratosis

the quality of human and veterinary health care systems substantially depends on key innovations often these were driven by the field of physics followed by interdisciplinary and intersectorial actions in engineering chemistry biology and medicine such as xrays in medical diagnostics ionizing radiation in cancer treatment and femtosecond lasers for precision surgery medical gas plasma technology was introduced to human health care a decade ago today accredited medical plasma devices are in daily operation in dozen dermatology centers in middle europe to improve wound healing in addition physical plasmas were shown to inactivate cancerous cells actinic keratosis is a skin disease affecting millions of europeans and making them prone to invasive and deadly skin cancer many of the available treatment options are associated with low efficacy pain risks andor high costs medical gas plasma technology is operated at body temperature and applied painlessly costeffectively and without notable side effects gas plasma has been suggested to be active on highgrade cancer cells but its activity against premalignant cells as in actinic keratosis is unknown by using beyond stateoftheart plasma multijet technology the primary technical objective of plasmact plasma against actinic keratosis is to support skin cancer prevention by medical gas plasma therapy of actinic keratosis plasmact does so by educating a new generation of applicationoriented scientists that are exposed to questions and findings from different scientific fields interdisciplinary from physics over chemistry and biology to medicine and capable of addressing questions in view of both academic as well as business needs intersectoral while incorporated in a vivid and productive environment across borders and cultures international
impact of the embryonic obesogenic environment on programming of cardiovascular diseases across the life course

50 of all pregnancies occur in couples with overweight or obesity leading to tremendous risks for pregnancy and longterm offspring cardiovascular complications my hypothesis is that an embryonic obesogenic environment induced by the mother and fathertobe predisposes to placental and embryonic programming of cardiovascular diseases across the life course this leads to the intergenerational cycle of the cardiovascular disease epidemic lifestyle interventions in pregnancy are emerging but unsuccessful in improving pregnancy or offspring cardiovascular outcomes due to inadequate timing unclear intervention targets and unpredictable outcomes obeseembryo aims to radically improve care for overweight and obese parentstobe by targeting the embryonic obesogenic environment to prevent development of cardiovascular diseases in offspring to fulfil this mission obeseembryo will provide crucial insights for evidencebased personalized prevention and intervention strategies from preconception onwards beyond stateoftheart aspects 1 first populationbased study on preconception and earlypregnancy as critical periods for adverse effects of an embryonic obesogenic environment induced by the mother and fathertobe 2 intergenerational metabolism studies using metabolomics and oralglucosetolerancetests to identify unknown metabolic pathways 3 cuttingedge imaging studies of cardiovascular development from embryonic life into adulthood to identify unknown developmental adaptations 4 longitudinal repeated placentalmirnastudies throughout the first trimester with an integrated approach to address replication tissue specificity functionality 5 translation of results into prediction models for offspring cardiovascular complications using artificialintelligence and an evidencebased clinical support system for overweight and obese parentstobe expected results will have great population impact on cardiovascular health in future generations