Dragon09/odtu_chatbot huggingface dataset:
sustaining public administration in modern democracies

the sustaining public administration in modern democracies supa consortium originates from the observation that public administrations in advanced democracies are increasingly overburdened administrative overburdening arises from a continuous increase in the number of rules that require implementation and the relative stagnation in administrative capacities this discrepancy between the rules up for implementation and the administrative resources available results in suboptimal policy outcomes lowquality public services and inconsistent implementation practices in view of this assessment it is the central objective of supa to examine strategies for enhancing the capabilities of the public sector to cope with the escalating challenges of administrative overburdening to this end supa pursues two interrelated objectives the first one is to examine how decisionmaking procedures and practices can be improved to limit the overall burdens placed on the administration the second goal is to explore how administrative structures can be reformed to manage ongoing rule growth effectively supa examines patterns of rule growth and the resulting administrative changes and challenges in six european states denmark france germany norway spain and the netherlands and the european union based on a combination of qualitative and quantitative methods supa 1 evaluates the effectiveness of socalled ruleoffsetting schemes
research ethics and integrity for the green transition

there is growing awareness of the importance of having all sectors of society adapt to face a range of globalenvironmental and climate challenges taking into account intergenerational justice these challenges require developingan encompassing framework for research and innovation ri to address environmental and climate ethics and integrityissues which relate not only to ri involving potentially significant environmental and climate repercussions eg riin the area of electromagnetic fields but also ri specifically aiming to develop knowledge and technologies to addressenvironmental and climate challenges eg geoengineering or biotechnology in food systems re4greens maingoal is to contribute to a european research area era ethics and integrity framework for research andinnovation activities designed to support the transition to a sustainable economy and society as envisioned by theeuropean green deal while ri has too often been part of the problem of environmental degradation and biodiversityloss a central pillar of the european green deal and associated legislation is to promote new technologies and sustainablesolutions to reach net zero emissions in the eu by 2050 and advance a range of other climate and environmentalobjectives based on a bottomup approach that uses the social lab methodology to reflect diverse stakeholder expertisere4green will develop operational research ethics and integrity guidelines recommendations and training materialsand programmes for researchers ethics and integrity experts and advisors and ethics review boards to make sure riactivities more holistically contribute solutions toward the green transition
evaluating linkages between phytoplankton community structure and carbon export using bgcargo floats

marine phytoplankton are a primary vector in the transport of carbon dioxide from the atmosphere to the ocean interior via the biological carbon pump the magnitude and efficiency of this flux hinges on phytoplankton community structurethe relative abundance of different phytoplankton groups present within a given water mass therefore accurate estimates of phytoplankton community structure are crucial for understanding global carbon cycles and for anticipating the impact of global climate change phytoplankton distributions within the global ocean are typically inferred from biooptical proxies reflecting phytoplankton physiology eg chlorophyll fluorescence or concentrations of particulate carbon eg attenuation coefficients or optical backscatter coefficients the deployment of biogeochemical argo bgcargo autonomous profiling floats is transforming the global coverage of these measurements providing new insight into connections between phytoplankton distributions and export processes however few studies have evaluated relationships between biooptical proxies as measured by bgcargo floats and direct measurements of phytoplankton community structure and none have performed an intercomparison of these relationships across different ocean basins therefore i propose to 1 utilize a combination of novel and existing flow cytometry methods to estimate groupspecific phytoplankton biomass across four disparate ocean provinces 2 evaluate the biooptical proxies that best predict groupspecific phytoplankton biomass within each province 3 leverage relationships identified in objective 2 to develop a novel transfer function for estimating phytoplankton biomass based on biooptical proxies alone and 4 apply this function to existing bgcargo data to quantify the importance of variability in phytoplankton community structure to carbon export to the mesopelagic zone as compared to other mechanisms
human adaptation to different altitudes through time and climatic changes

the evolution of homo sapiens has always benefited from its ability to adapt to the most diverse environments the subject of the adaptation of human groups to the environment has been of interest to scholars whose attention is often turned to cases of adaptation to environments with extreme conditions and to the socalled ecological niches however little attention has been given to the choice of human groups to occupy extremely different environments high mountains higher than 2000 meter asl vs lowlands and how high altitude settlements relate to the lowland sites in the framework of the land management this is particularly the case of the finale pleistocene to midholocene period in the horn of africa huma will be the first project to fully explore the contribution of a multidisciplinary and integrated approach to the understanding of human adaptation to the different environments in the later stone age of the horn of africa this will be achieved by integrating the most uptodate approaches in lithic technofunctional analysis with organic and inorganic residues analysis on lithic artefacts and dental calculus analysis focusing on archaeological sites from ethiopian highlands beefa cave a site discovered in 2019 and somali highlands and plains huma will investigate the role played by the climate played in the development of the cultural traits and how environmental factors may have fostered specific adaptations to different ecological niches and encouraged seasonal use of themlithic technofunctional analysis residues analysis archaeobotany experimental archaeology dental calculus analysis and adna analysis will be applied in order to answer the research questions both the university of florence and the university of connecticut are the ideal environments for undertaking the proposed crossdisciplinary research as they will contribute with their theoretical methodological and professional resources to reaching the projects goals
revolutionising the diagnosis of multiple sclerosis with the first bioinformatic diagnostic kit that allows early detection with a simple blood test

multiple sclerosis affects around 700000 people in europe and 28 million worldwide it is the most common chronic neurological disease in young adults in developed countries and the main cause of disability after traffic accidentscurrent diagnosis process takes one year on average which makes pharmacological treatment start late producing irreversible damage in patients and a worse prognosis combined with the high rate of misdiagnoses 20 it leads to a healthcare cost of around 20 billion every yearala diagnostics is revolutionising ms diagnosis with the first ms diagnostic kit based on our patented recombinant protein which is the only specific and clinically validated biomarker that exists for the diagnosis of ms in blood our diagnostic test is fast easy cheap noninvasive suitable for early diagnosis of ms and easy to integrate into daily clinical routine
scattering approach to thermodynamics of quantum systems

understanding thermodynamics in the quantum regime involves the understanding of how energy and information are exchanged between a quantum system and its surroundings although the laws of thermodynamics are well understood for macroscopic classical environments advancements in quantum technology press the need for a microscopic approach which treats the surroundings as a quantum system in its own right this project which i call scattering approach to thermodynamics of quantum systems satq aims at providing such an approach it relies on a quantum treatment of the surroundings as particles which travel in space and scatter with a quantum system the starting point of satq are stateoftheart results showing how the scattering approach with massive particles goes beyond existing collisionbased approaches to thermodynamics of quantum systems by explaining the notions of heat and work in a fullyquantum fashion the plan of the satq is then to extend the scattering approach to situations of greater theoretical and experimental relevance where particle statistics are important and when incoming particles are photons this is essential in quantum transport and optics setups where the scattering approach can be applied in parallel the plan of satq is to establish a connection between the scattering approach and more abstract approaches to thermodynamics based on resource theories bringing the latter closer to reality since scattering is ubiquitous in nature and physics experiments i expect satq to produce new foundational results in the field of quantum thermodynamics which can be directly tested in modern experiments
myopia from genes and environment to cellular responses and treatment

in modern industrial societies myopia has become an important ocular health problem of young people due to its increased incidence and associated complications which pose a significant risk of blindness already in the middle life span current treatment options have limited effects with a maximum reduction of axial elongation by about 04 mm over several years equivalent to a reduction in myopia by only about 1 d eye growth is controlled by an interplay of different biochemical pathways one inhibitory stimulated by image plane in front of the retina and one stimulatory image plane behind the retina a novel future strategy would be to activate the inhibitory pathways rather than inhibit the growth stimulating pathways standard target in most studies at present interventions to activate growth inhibition are poorly studied the influence of environmental factors spectral composition of ambient light and geneenvironment interactions specific gene variants and their interaction with key lifestyle exposures on eye growth and refractive development will be investigated new pharmacological targets will be identified and tested and biomarkers established to detect the onset of myopia at an earlier stage it will be studied how choroidal hypoxia relates to choroidal thinning and axial eye growth and how it interacts with the metabolic processes in the retina and sclera new measurement techniques will be developed that implement artificial intelligence algorithms to improve diagnostics in myopia studies especially in the periphery of the visual field the proposed intersectorial and interdisciplinary myotreat project including anatomy physiology pharmacology optics and genetics will train phd students in myopia research and generate and disseminate novel research results the ultimate scientific goal is to identify new strategies for myopia therapy through hypothesisdriven translational research in various animal models as well as in humans
ecoevolutionary dynamics and the maintenance of organismal diversity

there is growing evidence of rapid evolution leading to entangled ecoevolutionary dynamics however we are only beginning to address what this implies for maintenance of biodiversity in nature community ecology studies how species diversity is maintained in communities despite negative interactions separately population biology studies how phenotypic and genetic variation is maintained in populations despite selection and drift these two questions are interlinked but usually addressed independently not considering the other level intriguingly genetic variation could help maintain species diversity and reciprocally diversity could help maintain variation forming a positive feedback loop however this hypothesis has not been empirically tested in complex ecological networks because maintaining such networks in the laboratory is a major challengei propose to experimentally test this hypothesis using a uniquely tractable network of tropical rainforest drosophila and their parasitoids 6 fly and 5 wasp species that i developed to allow multigenerational microcosm experiments we will manipulate species diversity and genetic variation of all species in a factorial design to test the hypothesis we will then explore the mechanisms of interactions between diversity and variation focusing on rapid evolution to link the findings to natural ecoevolutionary dynamics we will investigate mechanisms maintaining diversity and variation in the wild based on the empirical work we will advance ecoevolutionary concepts of organismal diversity and stabilitythis project will provide a causal test of the interaction between maintenance of diversity and variation thus linking two key questions in ecology and evolutionary biology uncovering the specific coexistence mechanisms will allow us to predict the importance of diversity variation feedbacks in other systems with important implications for conservation of biodiversity
decentring the study of migrant returns and readmission policies in europe and beyond

gaps is a comprehensive study on the drivers of return policies and barriersenablers in international cooperation on returns the project examines the disconnects between expectations of return policies and their actual outcomes by decentering the dominant onesided understanding of return policymaking gaps will a scrutinize the shortcomings of the eus governance of returns with both its internal and external dimensions b analyse enablers and barriers of international cooperation c shed light on the perspectives of migrants themselves to understand their knowledge of return policies aspirations and experiences by taking a close look at governance cooperation and actors agency the project is able to suggest new avenues for international cooperation develop recommendations for stakeholders and explore alternative pathways to returning migrants the project combines its decentering approach with three innovative concepts a focus on return migration infrastructures that enable gaps to analyze governance fissures an analysis of return migration diplomacy to understand how relations among eu mss and with third countries hinder cooperation on returns and a trajectory approach that uses a sociospatial and temporal lens to understand migrant agency the project achieves its aims via multidisciplinary qualitative and quantitative comparative research in 11 countries in europe africa and the broader middle east including afghanistan the project involves wideranging and innovative impacts including the creation of interactive data repository on returns a return cooperation index return governance indicators policy briefs and workshops the formation of stakeholder expert panels a digital storytelling and video series the launching of massive open online course mooc as well as open access policy and scholarly publications
an innovative filtration system to improve the coagulation properties of plasma units to treat patients with massive bleeding

around 40 of deaths worldwide are due to bleeding which establishes haemorrhage as the most common cause of preventable death early intervention is generally sought by transfusing red blood cells plasma and platelets at a ratio of 111 however this can lead to increased bleeding and death plasfree is tackling this unmet demand of novel therapeutic approaches for haemorrhage by developing clearplasma an innovative filtration system that extracts plasminogen from plasma leading to an efficient treatment for massive bleeding clearplasma also allows to reduce up to 45 of the number of plasma units required during transfusion plasfree will be part of a booming global blood transfusion market valued at 634 billion with the eic support plasfree aims to deliver substantial global impact for patients and healthcare systems by accelerating the development of clearplasma as well as scalingup and conducting clinical validation to prove the devices safety and efficacy
ai for health evaluation of applications datasets

the proliferation of artificial intelligence ai is on the rise and yet there remains a lack of consensus on standardised approaches for responsible implementation in europe there is a strong push to regulate ai particularly in highimpact societal applications such as biomedicine and healthcare the objective of ahead is to create a transdisciplinary diverse and global community drawing on the expertise of professionals in biomedicine ethics ai development software engineering sociology psychology law gender studies and relevant stakeholders dedicated to the ongoing effort of tackling challenges and setting important standards in an everchanging landscape together the community will gather consolidate and put into practice established principles and guidelines building a methodology and a platform to evaluate aibased systems for biomedical and healthcare applications to ensure the compliance with legal ethical technical scientific and regulatory standards the project will extend the fucntionalities of openebench elixirs benchmarking platform for bioinformatics tools to provide a platform for these assessments the community will also establish an observatory to collect and curate existing guidelines best practices and principles for ai assessment in biomedicine and healthcare across multiple disciplines technical societal legal etc ahead will encourage responsible ai innovation through constant collaboration and knowledge exchanges to continuously meet the demands of the fastchanging ai landscape and ensure that quality healthcare for all people is never compromised and only enhanced the proposed project is the beginning of a sustained endeavour that would greatly benefit from mobility grants to enhance community bonds and foster collaborative efforts toward this goal
eit manufacturing business plan 20232025

the main goal for the years to come is the transformation of eit manufacturing into a wellregarded service organisation offering qualified services to the european manufacturing domain this transformation will include all parts of the organisation the pillars the clcs and the manufacturing sasu an extensive catalogue of possible service offerings has been established and prioritised the first results have been achieved already according to our gotomarket strategy services will be piloted by the clcs or the manufacturing sasu and if successful rolled out over the whole organisation the first portfolio of startups with financial sustainability agreements has been established with an estimated valuation of more than 2 millioneit manufacturing will focus its investment in the next three years on the european manufacturing system taking an integrated european approach of all pillars innovation education ris business creation and communicationthe european manufacturing system will play a key role in the circular economy it will link the steps of value creation processes in a multidimensional way in order to identify the environmentally economically and socially sustainable favourable alternatives for each step going from an idea to a finished product process or service with europes sensitivity for sustainability and its ingenious talents in developing innovative technologies processes and means of collaboration europeans are destined to lead the way to further evolved and improved manufacturing systems eit manufacturing in cooperation with its partners and ecosystem helps drive this leadership by postulating the european manufacturing system as a strategic objective for the european manufacturing industry with global implications the business plan implementation will fully comply with the eit financial sustainability principles kic fund principles innovation principles eit ris hub minimum standards and good governance principles
high performance half heusler thermoelectrics for waste heat recovery

this project aims to develop highperformance lowcost and environmentallyfriendly half heusler hh thermoelectric te materials for waste heat recovery in midtemperature applications it is an interdisciplinary research program combining research actions from five different scientific fields computational materials physics chemistry nanotechnology materials science and manufacturing engineering theoretical approaches and calculations will support the experimental investigations for the discovery and development of new n and ptype hh materials with the potential for high te performances a range of different strategies will be implemented in order to optimize their electrical transport properties and achieve in parallel high reductions in thermal conductivity through effective phonon scattering targeting to efficiencies with te figureofmerit close to 2 the final objective of the project is the construction of a prototype te device using the developed optimized materials and the evaluation of the final efficiency and produced power output of the device the interdisciplinary nature of the project will give the researcher the chance to gain training and experience from diverse disciplines learning new methodologies expanding his scientific horizon strengthening his professional maturity and becoming more independent for an academic positionhipert will have a high impact on scientific community while in logterm it is anticipated to be beneficial for the economy and society the hipert research outputs will introduce new scientific concepts and will inspire further research for the development of highperformance thermoelectrics in parallel it is expected to open the road for the development of hh te generators in industrial level creating attractive opportunities for european smes and companies to be involved in largescale rd projects aiming to bring hh thermoelectrics in the market as an efficient sustainable energy technology
yuman improving future care with autonomous mobile robots

yuman is a deeptech danish startup developing healthcarecentred mobile robots unique in the global market specifically designed to assist nurses by automating the transport of small items in hospital wards like food laundry or medical equipment unlike other robots we are creating a practical solution around the nurses needs combined with stateoftheart ai algorithms that allow our robots to be intelligent and assist nurses in a very diversified variety of transport tasks our research shows that on average nurses spend 37 of their time transporting food medicine and laundry this causes them a lot of stress and work pressure our goal is to free up nurses from these simple but timeconsuming routine tasks so they can spend more time with their patients yuman was founded by sara lopez ceo honours computer scientist experienced in software engineering ai humanrobot interaction and computer vision sara is a young woman entrepreneur driven by integrating robotic technology into the healthcare systems sara thrives on solving the global shortage of nurses using stateofthestart robot technology together with her team of dedicated and experienced engineers at yuman the women techeu grant of eur 75000 will help us build our mvp and create a robust technical foundation it will allow us to conduct hospital tests and mature our technology from trl 4 to trl 7 with the successful test in hospitals the women techeu grant would have helped us prove its commercial feasibility and product market fit