Dragon09/odtu_chatbot huggingface dataset:
microbiome biobanking ri enabler

microbiomes comprise communities of microorganisms ie microbiota that includes bacteria archaea protists fungi and microalgae and their theatre of activity ie structural elements metabolites signal molecules mobile genetic elements as well as surrounding environmental conditions microbiomes play a key role in maintaining life on earth by providing a range of essential ecosystem services and are indispensable for the health of plants animals and humans thus there is a wide consensus that by harnessing microbiome functions society would be better placed to tackle global challenges such as food security health and wellbeing food waste management and climate change mitigation to facilitate the science necessary to achieve key advances in microbiome research methodologies and technologies to capture or create ensure stable longterm maintenance and experimentally perturb microbiomes are required research infrastructures currently lack optimized methodologies and technologies to preserve and provide access to microbiome samples and massive amounts of associated data microbe is designed to address these issues by building upon and connecting 1 technical solutions for microbiome preservation propagation and functionality assessment 2 novel ecological concepts ie core microbiome and microbial keystone taxa and 3 data infrastructures in addition microbe will address essential framework issues such as standardization ethical and legal requirements and new business opportunities participation of relevant european research infrastructures ie bbmrieric mirri elixir and embrceric to ensure that community needs are properly addressed and that developed solutions are efficiently taken up by the infrastructures themselves and by their user communities long term ambition is to ensure widespread uptake in microbiome research communities and thus support the development of novel microbiomebased applications
massivebinary evolution across the metallicity ladder

do massive stars undergo supernova explosions when collapsing into black holes what mechanisms drove the cosmos into an epoch of reionization how was dust produced in the early universe scarcely any field of astronomy remains unaffected by massive stars stars born with more than eight solar masses yet studies in the local universe reveal substantial gaps in our understanding of massive stars related to mass loss internal mixing corecollapse and stellar interactions uncertainties worsen at the lowmetallicity conditions of the early universe the primary reason for this a severe lack of empirical constraints on massive binaries across the metallicity axis driven by the rarity of massive stars and the shortage of adequate monitoring campaigns to study themmetal leverages hundreds of hours worth of novel spectroscopic and interferometric data collected as pi using observatories such as the very large telescope vlt and the hubble space telescope including a vlt large programme 116hr 2023 2025 these campaigns monitor thousands of massive stars in our galaxy and the magellanic clouds targeting unevolved obtype stars evolved wolfrayet and oebe stars and elusive black holes metal will elucidate the initial conditions evolution and ultimate fates of massive stars at three metallicity anchors groundbreaking outcomes include 1 unprecedented statistics on the multiplicity initial mass function and structure of massive stars at low metallicity 2 a tenfold increase in the sample of dormant blackhole binaries and the first such sample at low metallicity and 3 a revised massloss prescription and a comprehensive binary characterisation of evolved massive stars at two metallicity anchors the deliverables will be the defining calibrators for nextgeneration evolution models of massive stars ushering in advancements in models of not only stellar evolution but galaxy evolution unresolved stellar populations and corecollapse supernova
atomistic modeling of advanced porous materials for energy environment and biomedical applications

metal organic frameworks mofs are advanced porous materials with multifunctional tunable properties offering great potential for energy environment and biomedical technologies the number of mofs is increasing at an exponential rate studying millions of mofs for different applications by random material selection using iterative experimental testing or bruteforce computational simulations is impossible the full potential of mofs for target applications can only be unlocked if the storage and transport properties for important chemical and biological guest molecules trapped in the pores of each mof are known in this project i will create a materials intelligence ecosystem for precisely assessing guest storage and transport properties of all mofs by combining stateoftheart atomistic calculations molecular simulations machine learning and data science integrated with past and future experiments i will focus on ten critical guest molecules to address the key societal challenges of our world hydrogen and methane to use mofs for clean energy storage ammonia carbon monoxide carbon dioxide nitrous oxide to use mofs for capturing toxic gas and combatting global warming fluorouracil methotrexate nitrogen oxygen to use mofs as nanocarriers for anticancer drug therapy and biomedicine the groundbreaking gains of my project will include the creation of the worlds first database for guest storage and transport properties of millions of mofs accurate assessments of new technologies by precise mofapplication matching and generating design guidelines for highperforming mofs to accelerate discovery of new materials my novel methodology synergizing theory and datadriven science will greatly extend the reach of current experimental and computational studies by discovering new thermodynamic theories that will be extendible to other material classes and providing atomiclevel insights into mofguest interactions that determine materials performances
doctoral network for a shared excellence of fluorescent lifetime imaging microscopy in biomedical applications

in flimagin3d which centres on fluorescent lifetime imaging microscopy applied to biomedical platforms in 3d ten talented doctoral candidates dcs will be recruited trained and supervised to cohesively establish the most robust user accessible and powerful flimbased platformnever achieved before and apply it to a wide range of applications in the biological sciences flimagin3d will generate ten dcs at the cutting edge of flimbased biological imaging who will spearhead and go onto catalyse clusters of flim excellence across europe each intertwined within a collaborative network that will extend beyond the timeframe of the program this doctoral network will train talented doctoral candidates in the essential theories underpinning flim and through the individual projects and extensive secondments in this network elevate their projects and skills and that of their secondment hosts to research excellence in flim flimagin3d addresses a significant knowledge gap in the field of photonics in biology by involving biomedical scientists in each and every aspect of development and design and cognisant of the wide variety of current platforms that require adaptability to such modalities in flimagin3d bringing together representatives with different applications and backgrounds we will identify and overcome barriers to flim imaging by developing the next generation of scientists who will develop a flim platform capable of extracting the greatest amount of information possible in a streamlined accurate and userfriendly manner in order to understand biology in disease differentiation development and interventions at a high resolution to achieve this goal the trained scientists will develop cheaper advanced hardware components with user friendly software that can build precise libraries for accurate machine learning classifications and plugandplay platforms and sensors to facilitate a wide range of applications
cultural heritage and immersive technologies for innovation forge

the main goal of heriforge is to develop a network of three interconnected placebased ecosystems in poland cyprus and turkey providing an excellent ri environment for innovation in the cultural heritage and creative industries with the responsible use of extended reality xr technologies and digital cultural heritage assets for the benefit of social resiliencethe heriforge project harnesses the expertise of three excellence hubs on xr technologies advanced it and digital humanities infrastructures as well as cultural heritage resources to provide an interregional ecosystem of innovation these hubs epitomise the quadruple helix model integrating academic institutions businesses public authorities and societal actors within their ecosystems in a bid to foster a real placebased innovation culture based on a strategic agenda and in line with regional or national smart specialisation strategies within the project these individual ecosystems will be transformed into the heriforge hubs networkthe project results in five key results including critical for the establishment of the innovation ecosystem including strategic impact package the fully operational heriforge hubs network xrdriven prototypes and services guidelines for building humancentric and trustworthy innovation ecosystemsas well as data orchestration platform
openaccess forecasting system of the health effects of air pollution

air pollution represents a major global environmental health problem 99 of the world population lives in locations where international air quality guidelines are not met overall ambient air pollution causes 42 million premature deaths every year worldwide half a million of which in europe alone available early warning systems of air quality are generally based on locationspecific thresholds of air pollutant concentrations they are entirely based only on forecasts representing the physical processes of atmospheric chemistry and they do not account for the inequalities in vulnerability of the exposed populations the ercfunded project forecastair will go beyond these limitations in health early warning systems by integrating air quality forecasting environmental epidemiology and the inequalities in vulnerability to implement a new method to issue public health alerts towards this aim i will estimate epidemiological models between air pollution observations and health records disaggregated by causes of disease and sociodemographic vulnerable groups i will use these models to transform biascorrected air quality forecasts into heath predictions i will analyse and compare the window of predictability of forecasts and predictions and i will use this comparative study to assess the predictability of the resulting health early warning systems so that they generate trust among public health authorities and endusers if successful forecastair will drive innovation by creating operational fitforpurpose early warning systems representing the health impacts of several air pollutants with a special focus on vulnerable populations
the international ecosystem for accelerating the transition to safeandsustainablebydesign materials products and processes

the iriss project aims to connect synergize and transform the ssbd community in europe and globally towards a life cycle thinking where there is a holistic integration of safety climate neutrality circularity and functionality of materials products and processes throughout their lifecycle to meet the eu green deal eu chemicals strategy for sustainability and un sdgs the uniqueness of iriss is that the consortium is built of core and network partners that represent the top components needed to build an euled permanent network ie policy industry applied science innovation and research education and that is selfsustaining and international in scopeiriss responds to the work programme with the following objectives1to develop a stateoftheart ssbd ecosystem that is supportive for the uptake and utilization of safebydesign sbd and sustainablebydesign susbd strategies by industry especially smes2to contribute to criteria and guiding principles for susbd development driven by the application of life cycle thinking in materials and product design and in line with ongoing work in european and international initiatives3to establish a structure for a permanent gender balanced inclusive international and sustainable experts network accessible for all relevant stakeholders4to develop ssbd roadmaps encompassing 3 agendas identifying 1 scientific research needs 2 skills competences and education needs and 3 knowledge and information sharing needs the roadmaps will be developed in a cocreation and inclusive process for the implementation of ssbd in industry and society including prioritised steps within research innovation skill demands management and governance5to develop a monitoring and evaluation programme that systematically scans for stateoftheart knowledge information gaps and translates these into specific rd questions and governance needs that feed into systematic roadmap updates
genomics of social structure and its implications for conservation

the habitats of most vertebrates are disappearing at an increasing rate with major consequences for their survival and that of humans increase in disease emergence and levels of poverty are two of its many impacts which pose a threat to a sustainable economy worldwide monitoring and managing species is essential to restore a sustainable use of resources genomics approaches provide a framework to quantify the health status of species using genetic diversity inbreeding and demographic history however such approaches have been widely ignoring a defining aspect of many threatened species social groups the fundamental units in which many species are organised live and reproduce through this mscaif i will develop a new framework using identitybydescent genomic information to infer socioecological parameters eg group sizes and migration rates essential for the survival of species taking advantage of new readily available samples of mouse lemurs this action will provide direct input to madagascar serving as a model to evaluate recent past anthropogenic actions and more vitally preview the impact of ongioing changes on the socioecology of species under alternative landuse scenarios this will be a general framework to study the social structure of many other species faced with similar environmental challenges across the globe the rising public awareness of ecological changes makes it an ideal time to share knowledge on biodiversity and i will strongly invest in outreach activities this action provides a unique opportunity for me to learn an essential set of skills on high level statistical genomic methods and nonmodel organisms genomics analysis coupled with cultivating an extensive new network of expert collaborations through this action i believe i will contribute to conservation genomics and specifically to lemur conservation while gaining invaluable assets for my career development as an independent researcher
comprehensive hazard identification and monitoring system for urban areas

the chimera project will provide a groundbreaking solution to the selected shortcomings and gaps in the cbrn security market the project aims to do so by developing a multiplatform command control cbrne system for responders dispatch and crisis centres providing an area of interest overview asset management and realtime data visualization as well as by developing a multipurpose heterogeneous sensor node for cbrne detection allowing for the integration of commercially available detection instruments furthermore the project aims to implement a realtime dispersion modelling software for cr agents to provide dispersion models and source estimations considering the 3d urban environment and to integrate data fusion algorithms combining data from different sensors from chemical radiological or biological layers to enable agent identification and false alarm reduction ultimately the chimera project will create a commercialready database combining c b and rn substanceagent characteristics with these solutions the projects outcomes will considerably enhance both the operational capabilities of the first response and crisis management teams and the safety of the onsite personnel all projectdeveloped components will function as individual units as well as part of the whole system in addition the chimera system will feature an open design to enhance its interoperability and facilitate other existing systems integration to illustrate the systems potential for realworld application it will be demonstrated before a live audience of stakeholders industry representatives and potential endusers in a realistic scenario
improving renewables penetration through plug and play microgrids

for africa to meet its 2030 sdg7 targets and ambition of attaining energyforall by 2040 and climate neutrality by 2063 the proportion of renewables in the current energy mix needs to be dramatically improved through robust and effective technologies sustainable business models a skilled technical workforce and an enabling regulatory environment repower will contribute to these efforts by demonstrating and validating a modular and scalable plug and play pnp microgrid system based on photovoltaics pv and biomass combined heat and power bchp augmented with a battery energy storage system bess and an intelligent energy management system ems and by providing tools processes and a roadmap to replicate the installation of this modular plugandplay microgrid system at any other location the modular and scalable repower microgrid system will build upon the solartainer an existing and containerised pvbess solution that has already been successfully piloted by project partner agt in 21 locations empowering 25420 customers in remote offgrid locations and providing 934 smes with power in mali niger and chad the new solartainer repower combined with a unique bchp solution will have the capacity and flexibility to provide distributed affordable reliable and stable electricity as well as heat and cooling to offgrid communities in senegal niger and madagascar compared to the average pvbased microgrids currently on the market for africa the repower setup including bchp will improve the renewable energy generation capacity of the existing plants by over 50 while also reducing the unit cost of electricity by about 60 70 allowing consumers to extend electricity usage to the productive use of energy pue such as farming water pumping food processing construction and other smallscale industries the modularity of the system allows sizing to meet the demands any specific application or locality thus matching energy supply with demand
complex regional economic systems in sustainable energy transition theory models empirics and policies for southern europe

against the backdrop of a looming global environmental crisis a sustainable energy transition driven by public and private finance and innovation paves the way for the emergence of novel technologies industries value chains consumption patterns etc under a technoeconomic paradigm that promises to lead to a great surge of development decoupled from environmental harm the diffusion and adoption of this new paradigm however seems to be too sluggish to avert ecological collapse uncertain in view of geopolitical conflict and the impending energy crisis and highly uneven in time and space due to coreperiphery disparities in europe this paradigm shift presents opportunities but also major challenges for peripheral regions which necessitate more radical industrial strategiesthis highly topical project will investigate from a theoretical empirical and normative perspective the energy transition dynamics of southern european regions their institutional technological and economic determinants their economic and environmental impacts and the policies needed for enabling these regions to forge their technoindustrial niches in the emerging value chains and to achieve green growth the project will combine schumpeterian postkeynesian and ecological economic theories under a systemic research programme and produce a cuttingedge formal model of a complex economic system embedded in the environment and undergoing energy transition at the empirical level it will employ advanced statistical and computational methods to test for the impacts of green technologies and to simulate alternative transition scenarios at the normative level it will frame the eu and national policy discourses on the european industrial strategy recovery plan and green deal with evidencebased insights on industrial policy the project is designed to boost the researchers career evolution and to consolidate his expertise and research skills through highquality training
design characterization and evaluation of biofilm eradicating hybrid liquid crystalline nanocoatings for new 3d porous orthopedic implants

orthopedic implantassociated biofilm infections represent a major public health and socioeconomic burden due the intrinsic tolerance of biofilms that behave as protective and immobile scaffolds to conventional antibiotics and immune system further their longterm and repeated antibiotic treatments lead to an increased potential of antibiotic resistance development here this interdisciplinary proposed project integrates innovative aspects of surface chemistry 3d morphological characterization of coated implants and precision engineering with attributes for production of much needed biofilmtargeting nanostructural implant coatings it also considers the urgent societal needs for introducing an effective flexible and universal approach in orthopedic implant patterning and functionalization for combatting and preventing implantassociated biofilms this core approach is based on controlled patterning with inverse nonlamellar lyotropic liquid crystalline phases having unique nanostructural versatility through prior precision priming of new 3d porous implant surfaces with tailormade coating method and their thorough characterization by using different modalities including gisaxs neutron reflection highresolution xray photoelectron spectroscopy and xray microcomputed tomography this is in combination with in vitro profiling on model implantassociated biofilm infections the project provides an environment with independent research activities for building my professional skills in a research topic at the interface of nanoscience surface chemistry and experimental medicine in addition to training at different synchrotron facilities my research career will be certainly advanced owing to the gained experience with stateofart biophysical tools and supervision of master students