Dragon09/odtu_chatbot huggingface dataset:
gender equality in museums exploring the transformation of female religious spaces and objects into modern museum contexts

this project examines the historical transformation of female religious spaces and objects into modern museum contexts in the 18th and 19th centuries numerous female monasteries in europe were abolished during secularization leading to the reinvention of their spaces as museums and the incorporation of sacred objects into exhibitions as a result the cultural memory of these spaces as womens convents faded away the projects aim is to uncover how the historical dispossession of female ownership of monasteries and sacred objects is evident in contemporary museum displays drawing inspiration from decolonize museums methodologies it seeks to propose innovative solutions for addressing gender challenges in modern museum collectionsto achieve this goal the project employs a case study approach with a primary focus on the essen cathedral treasury in germany this marks the first transdisciplinary examination of the treasury from a gendered perspective the research delves deeply into how gender binaries have historically influenced the representation of this collection their persistence in current exhibitions and subsequently the development of strategies to transform these representations which can be applied to similar collections
aida allergy immunotherapy based on designed allergens

allergy is a severe immune reaction to foreign substances known as allergens with respiratory and food allergies affecting 30 and 10 of the global population respectively a high structural similarity exists between pollen and food allergens therefore many people suffer from both types of allergies untreated allergies have detrimental effects on healthrelated quality of life family economics and work attendance allergy is treated as a chronic disease with a focus on reducing symptoms eg antihistamines which is cumbersome and expensive the only existing curative treatment allergen immunotherapy ait consists of up to 5 years of monthly exposure to low amounts of the triggering allergen until the immune system is desensitized unfortunately this approach is costly for healthcare providers and its efficacy varies being especially low for patients allergic to multiple pollen and foodstuff sources only 40 of patients choose to undergo ait and 20 of these terminate the treatment early due to strong side effects or lack of efficacy we propose the development of an urgently needed ait by treating several allergies at once achieving tolerance faster and reducing side effects
textile recycling excellence

the global consumption of textiles is increasing with global production of the two most relevant fibres cotton and polyester expected to grow by 40 before 2023 there is also no euwide plan on how to deal with the existing and anticipated textile waste currently less than 1 of the material used to produce clothing is recycled into new clothing in a closedloop process while 87 is landfilled or incinerated by january 2025 new eu directive 2018851 will require all member states to establish a separate household textile waste collection and respect increasing minimum recycling goals but the pure legislative approach cannot alone solve the growing textile waste problem based on estimates from experts we see that 1 of textile waste entering closed loops leads to 100b euros market loss each year if a 30 recycling rate is reached similar to average plastic packaging recycling rates we will be able to valorize a 30 billion eurosyear marketthe ambition of trex is to contribute to a paradigm shift from household textile waste into desired feedstock moreover we aim to demonstrate that this new commodity and the business models based on it can be completely implemented within the eu by involving major players across the whole value chain we aim to demonstrate that a new ecosystem approach with harmonized methods and quality criteria can lead to a better understanding of our current textile waste and therefore better upcycling rates into new garments we also intend to demonstrate that such products can appeal to consumers while at the same time be designed for further recycling our goal is to reduce co2 emissions by 30 across the complete value chain by 2030 by helping to end plastic wastethis project will arm the eu with a commercially viable option to tackle the textile waste and the environmental problems it causes whilst offering new fields to explore for eu businesses new knowhow for our citizens and new workforces for the future
jam with the flow microgelbased bioinks that assemble during printing

many of natures materials have exceptional properties because their structural organization resulted from the ondemand processing of compartmentalized materials i want to translate this principle to extrusionbased 3d printing ebp ebp is a booming fabrication approach in tissue engineering as it provides control over material deposition in the submillimetre range in a costeffective manner however due to the many requirements for printable biomaterials called inks only a limited number of chemistries can be effectively used and typically homogeneous network compositions are obtained even though biomedical and other applications require highly controlled inhomogeneities approaches providing high control over local material structure and composition are lackingto provide a solution i will develop a new class of microgelbased materials that jam due to the ondemand induced microgel swelling and undergo secondary crosslinking both in the flow resulting in a onestep printing of stable heterogeneous scaffolds with locally varying properties and compositions relevant for mimicking real tissues importantly the approach eliminates jamming steps before printing yields unprecedented control over local material composition and structure in the flow down to the submicrometre range and does not require postprinting crosslinking steps to stabilize the printed structuresinspired by natures compartmentalized materials and supported by preliminary measurements my microgels will serve not just as predefined building blocks but also as material reservoirs during printing the approach will be generalizable to different material systems and chemistries and as such holds great promise for a new generation of hydrogels and advanced inks with structural and functional properties precisely controlled during and via the printing process this will impact fields from tissue engineering to soft robotics agriculture food and cosmetics
magnetic soft matter for robotics

this doctoral network dn responds to the existing demand for training of a new generation of experts in the emerging subfield of soft robotics relying on the control of material properties by a magnetic field magnetic soft robotics materials involved are elastomers and complementary liquids filled with micro and nanometersized magnetic particles because the technical problems and tasks involved are complex and require knowledge from different fields of science and technology the consortium is composed of 7 academic and 2 industrial beneficiaries originating from biology materials science physics and robotic engineering further 3 associated partners are involved in research and transferableskills training the research program will be directed towards demonstration of a number of mobile robots and robot gripping devices with the necessary electronic and control systems where the essential functional parameters eg the friction coefficient of the robot shoe or the stiffness of the finger joint etc are controlled by permanent or electromagnets on the way to the functional prototypes the synthesisstructureproperties relationships of magnetic soft matter are to be investigated both experimentally and theoretically because hitherto the required dependencies are not available and the underlying physical phenomena are not completely understood the mechanical part of the soft mobile robots with integrated magnetic soft matter the necessary electrical and magnetic control circuits and the adaptive control algorithms for realtime magnetic field tuning and robot behavior generation are to be developed the carefully designed training program will provide the necessary minimum of interdisciplinary specialist knowledge to all doctoral candidates and prepare them for meeting the challenges in their subsequent careers be that in academia industry or as entrepreneurs eg by obligatory exposure to industrial environment during secondments
multimodal multitask learning for multiscale bathymetric mapping in shallow waters

accurate detailed and highfrequent bathymetry coupled with the important visual and semantic information is crucial for the undermapped shallow coastal areas being affected by intense climatological and anthropogenic pressures regular uav and satellite imagery have the potential to frequently and consistently map those areas to different extents and detail providing ground breaking key information however optical properties of water severely affect images and refraction is the main factor affecting their geometry current structure from motion sfm based solutions for refraction correction are slow and costly satellite derived bathymetry sdb methods deliver faster results over huge shallow areas albeit in lower spatial resolution failing to handle nonhomogeneous seabeds recent methods based on convolutional neural networks cnns deliver either only the bathymetry or the semantics of the scene tackling those problems separately and in one scalemodality at a time they are mostly dedicated to satellite images failing to address the challenges of shallow waters being also inefficient for uav images preventing higher resolution results magicbathy will establish an advanced deep learning framework for lowcost shallow water mapping by developing a novel boundaryaware multitask multiscale and multimodal learning approach for bathymetry and semantics together exploiting single either uav or satellite imagery to overcome the domain gap generalize and improve performance selfsupervised indomain representation learning will be performed to enhance the spatial resolution of low resolution satellite images and hence of the resulting bathymetricsemantic maps a conditional generative adversarial network cganbased super resolution framework will be developed dealing with the special challenges of shallow water imagery frameworks models and results will be published in open access enabling the rapid progress in shallow water mapping worldwide
see you online a phenomenological investigation of the limits of empathy in the online sphere

according to phenomenologists empathy is the fundamental way we grasp others as experiencing expressive subjects it is typically supposed that empathy requires a facetoface encounter when we are on zoom together instant messaging one another on whatsapp looking at instagram posts or tiktok videos how do we experience one another online do i only have indirect access to others or can i empathetically perceive them when i wave goodbye to you in person does my parting see you online make any sense while there is much debate about whether the internet is good or bad for sociality such discussions fail to address the question of how we encounter others online in the first place see you online a phenomenological investigation of the limits of empathy in the online sphere will provide a phenomenological analysis of the structures of our online social experiences and explore the role empathy plays in online sociality the investigation is underpinned by a novel methodological approach that integrates insights from the phenomenology of sociality and the philosophy of perception the project will undertake a platformsensitive analysis that aims to do justice to the complexity and plurality of our technologically mediated intersubjective encounters and produce i a novel theoretical framework for analysing our online social encounters ii a platformsensitive taxonomy of online interpersonal experiences and iii an analysis of the limits of the phenomenological concept of empathy by considering its application across various online platforms to achieve the research objectives the project is divided into three interrelated strands of inquiry i perceiving the lived body online ii sharing space online and iii taking time online in the shadow of covid19 where many of our social practices moved online the need for a finegrained platformsensitive analysis of online sociality is more pertinent and important than ever
cloudbased platformagnostic adversarial ai defence framework cpaid

cpaid envisions researching designing and developing a cloudbased platformagnostic defense framework for the holistic protection of ai applications and the overall ai operations of organizations against malicious actions and adversarial attacks cpaid aims at tackling both poisoning and evasion adversarial attacks by combining aibased defense methods eg lifelong semisupervised reinforcement learning transfer learning feature reduction adversarial training security and privacybydesign privacypreserving explainable ai xai generative ai contextawareness as well as risk and vulnerability assessment and threat intelligence of ai systems cpaid will identify guidelines to a guarantee security and privacybydesign in the design and development of ai applications b thoroughly assess the robustness and resiliency of ml and dl algorithms against adversarial attacks c ensure that eu principles for ai ethics have been considered and d validate the performance of ai systems in reallife use case scenarios the identified guidelines aspire to promote research toward developing certification schemes that will certify the robustness security privacy and ethical excellence of ai applications and systems
advanced packaging and heterogeneous integration for electronic components and systems pilot line

as a contribution to the eu chips act the research fab microelectronics germany fmd proposes an advanced packaging and heterogeneous integration for electronic components and systems pilot line apecspl which combines the generation of globally competitive high technology that addresses the specific needs of german and european industry and enables a lowthreshold easily scalable industrial transfer the apecspl will include novel characterization quality assurance testing reliability methodologies test methods to assess the security of microelectronic systems against physical attacks and a system technology co optimization stco framework together with the 2 nm gaa imec 5 nm fdsoi leti and wide bandgap semiconductor pilot lines also planned within the eu chips act the apecspl is also in a position to become an essential component on the way to the vision of a paneuropean pilot line facility and thus an indispensable pillar for achieving the eu chips act target of bringing 20 of the global supply of chip production back to europe in addition apecspl offers a onestop shop for a very broad international customer base in basically all classic vertical industrial sectors including large companies smes and technology startups demonstrators are planned to evaluate how the elements of the pilot line work together the fmdofc office managed by fraunhofer as legal entity is responsible for operational management as a first step for additional european rd partners the project partners imec leti vtt imbcnm csic inl forth and tu graz will be included the shortage of skilled workers and scientists is of particular interest in the project better integration of a gender dimension into research and innovation content will be an essential part of the project systematic ecodesign that generally minimizes energy and resource consumption is in line with the eu green deal
sharing and reusing clinical trial data to maximise impact

data from clinical trials are a rich source of clinical information highly structured and clearly explained by the accompanying protocols responsible sharing of such data holds incredible promises to increase value and decrease waste in medical research it is built on principles ethical scientific governance structures skills and operation infrastructure clinical trial data sharing ctds is an emerging activity in academia as well as in the pharmaceutical industry both communities develop models for organising and performing ctds thereby several issues gain relevance enhancing data sharing with researchers improving public access to clinical study information sharing results with patients participating in clinical trials certifying procedures for sharing clinical trial information and reaffirming commitments to publish clinical trial results we see a developing field of professional activities that need well educated experts to define and implement best practices training such a new generation of experts in ctds requires specific teachings with a focus on clinical trial transparency and reproducible research practices it should include topics such as clinical trials regulations ethical legal and social issues informatics data science biostatistics and metaresearch as well as domain expertise across different medical fields in order to gain a deep understanding of this developing field research activities should be based on metaresearch approaches those activities focus on research on best practices for ctds developing methods to make efficient use of shared data eg methods to augment randomised clinical trials perform independent participant data metaanalysis or estimate personalised treatment effects and measuring ctds impact
exevirs xvr011 a best in class nanobodybased biology that broadly neutralizes sarscov1 and sarscov2

xvr011 exevirs clinical lead candidate has emerged from scientific research from labs of highly regarded virologist xavier saelens and biochemist nico callewaert nonclinical data has recently been published in cell and a preprint on biorxiv xvr011 is a nanobodyfc fusion has bestinclass potential neutralizes sarscov2 and minimizes the development of lung damage in hamsters the lamaderived singledomain antibodies are smaller than human antibodies and can attach to parts of a virus that are difficult to access for the human immune system xvr011 inactivates spike proteins and sterically blocks spike binding to ace2 preventing virus from entering a human cell stopping viral replication this supplements the patients own immune response in a critical time window during which many covid19 patients immune system reacts too slowly giving it more time to do its job and eliminate the virus it binds to a unique highly conserved epitope in the viral receptorbinding domain its epitope is much less susceptible to human antibody immunity pressure that can lead to viral escape resulting in retained potency against such escape variants it thus neutralises the rapidly spreading sarscov2 variants and exhibits a unique wide scope binding across the sarbecovirus clades furthermore xvr011 has been optimized for stability safety and manufacturability xvr011 received approval from the belgium regulators to move into its phase 1b seven ip patents were filed early on during the pandemic exevir has surrounded itself with both a team of experienced entrepreneurs and is backed by a mix of private and public experienced partners and has a strong board of directors bringing with expertise across the whole value chain the objectives of this proposal is to demonstrate xvr011 safety and efficacy in a global phase 2 to strengthen its nonclinical package including neutralising variants data setup its manufacturing process and progress its regulatory pathway
hierarchical gradient metals by additive manufacturing

over the last decade the steadily increasing research on gradientstructured metals and alloys has demonstrated great successes of this biological and natureinspired concept to evade the strengthductility tradeoff dictating in regular engineering materials however given the intrinsic limitations of conventional manufacturing methods the currently engineered structural gradient materials are all featuring a linear pattern usually from exterior to interior with only simple structures of grain sizes twin spaces lamellae spaces or combinations a recent preliminary study of my research team accidentally discovered that additive manufacturing could produce periodic and 3d gradient microstructures with not only simple microstructure features but also hierarchical ones from grain size to subgrain boundaries and even lattice distortions the hierarchical gradient microstructure keeps the same level of high strength but doubles the failure strain compared to the conventional microstructures this inspires us to systematically investigate the possibilities and boundaries of these new hierarchical gradient microstructures by additive manufacturing due to its extreme complexity across multiple scales and physics laws in correlating process microstructure and property of such new materials we aim to develop a systematic approach for designing hierarchical gradient microstructures by using design of experiments indepth and multiscale characterization methods multiphysics and multiscale numerical models and data informatics the intelligent integration of the physicsbased and datadriven models will eventually boost the dimensionality efficiency and accuracy of the modeling approach for the design of the complicated hierarchical gradient microstructure in 3d it will provide a powerful digital and sustainable way for the design of new materials andor processes and evaluation of material performance
how vertically transmitted gut microbes and immune genes synergistically direct antimalarial defence in birds

mounting an appropriate and effective immune response is critical to protect an organism from infection in vertebrates the adaptive immune system ais plays a central role in immunity and evidence is accumulating that its development is governed by intricate crosstalk between host immune genes and gut bacteria gb this implies that specific synergisms exist between bacterial taxa and ais mainly encoded by the highly polymorphic major histocompatibility complex genes mhcs to promote optimal immunity however the specific associations between gb and mhcs in defence against parasites and their potential effects across generations are poorly resolved in one of the largest vertebrate classes the birds bornthisway will close major gaps in our current understanding of immune consequences of gbmhc crosstalk in wild birds using two ideal study populations the action will capitalise on my and my hosts prof helena westerdahl extensive backgrounds in avian gut microbiomes and avian adaptive immunity respectively bornthisway will i establish how gb and mhc act in concert to defend against avian malaria parasites ii determine if synergistically optimal protection is transferred across generations and iii test immune consequences of gbmhc crosstalk disruptions bornthisway will add a new dimension to hostpathogen interactions in wild birds generate novel fundamental insights into the adaptive significance of gbmhc crosstalk and provide transformative insights of conceptual and empirical value to transgenerational immunity in vertebrates