Dragon09/odtu_chatbot huggingface dataset:
a coordination and support action to prepare uncaneu platform

the 15month coordination and support action 4uncaneu will generate a strategic agenda to launch uncaneu a european initiative to understand cancer proposed by the mission board and the european beating cancer plan this research agenda will be built with the final aim of achieving a new breakthrough in cancer prevention and treatment that will contribute to saving european citizens lives and help ensuring an optimal quality of life to disease survivors to reach a new level of understanding uncaneu will take advantage of recent advances in research data generation and data sciences reliable highquality cancer research data generated by experimental model analysis and collected from longitudinal followup of cancer patients will be shared and integrated at an unprecedented scale within a federated cancer research data hub in the context of the general data protection regulation this information will be used by relevant players in europe and beyond to address urgent and essential scientific and medical challenges in cancer prevention early diagnosis treatment and survivorship in males and females of various ages these challenges identified in close interaction with european patients and citizens will be tackled through competitive ambitious and innovative crossborder and transdisciplinary research programmes built in a problemsolving manner the definition of challenges will integrate inequalities in cancer research across regions and member states in order to boost the research potential of lessdeveloped regions in europe players will be committed to open science principles including fair findable accessible interoperable and reusable guiding principles for scientific data collection management and stewardship the new understanding gained from the collection and analysis of this wealth of data will apply secondarily to other diseases
tracing ramifications the contemporary artists periodical in the expanded field of arts publishing

ramifications investigates the central role of the contemporary artists periodical in mediating and driving shifts in the art communication and publishing systems since the early 2000s artists periodicals have become sprawling and live structures engendering new business models and expansive modalities collaborations and networks these periodicals produced by artists as part of their own language and work offer a rich opportunity to analyse the expanded field of art publishing and to think critically about contemporary arts fluid accelerated and networked expressions deep art historical questions concerning arts autonomy the meaning of public collectivity communication and knowledge in current artistic and publishing practices will be explored through a crossdisciplinary case study and practiceenhanced approach that will offer the theoretical vocabulary and practical tools to comprehend the fluidity and expansiveness that this project aims to investigate curating an artists periodical exhibition conceiving and hosting a 4episode podcast on art publishing and organising an international workshop on expanded publishing will not only complement the researchs findings but outline new directions in this growing field of study by focusing on 3 global artists periodicalseflux chimurenga and white fungusthe research contributes to the wider goal of giving voice to marginal stories situated outside of the northwestern axis studying and communicating these histories and contributions to the developments of 21st century art is an important step towards changing public perceptions encouraging inclusivity and correcting inequalities in the way art is interpreted the gf will be carried out at the san francisco state university universit iuav di venezia and at the triennale di milano to develop my skills and competencies and allow me to become a leading scholar in contemporary art history and publishing
developing environmental sustainability circularity assessment methodologies for industrial biobased systems

the main objective of the escib project is to support the sustainability of the biobased economy in europe to achieve this escib will develop assessment methodologies and thus contribute to the standardisation of such methodologies the aim is to develop a comprehensive robust and fully operational methodology to assess the sustainability of biobased systems at various technologyreadiness levels trls this methodology is based on a holistic lifecycle approach to evaluate the environmental impacts and circularity along biobased value chains potential socioeconomic tradeoffs will be addressed and included in the methodology escibs integrated way of analysing environmental and circularity impacts along biobased value chains is also fully in line with the ambition of the european green deal egd and the circular economy action plan ceap with the involvement of five innovative industry partners in the consortium which produce biobased products in different sectors escib will ensure high applicability of the method which can be used by certification organisations to label and certify products for the benefit of consumers and society finally the results will give orientations for research and innovation programmes in the biobased sectors
sharing researchers passion for enhanced roadmaps the european researchers night in italy 20222023

sharper brings together young generations citizens and researchers to develop roadmaps to a better and desirable future researchers are passionate about future and they constantly design adapt and implement roadmaps to contribute to build it this process increasingly involves young generations and citizens at large and make researchers and citizens travel mates curiosity driven choices and social needs together mould researchers agendas and generate roadmaps that need to be constantly enhanced to effectively tackle new challenges researchers are increasingly at the heart of this process and the acronym sharper sharing researchers passion for enhanced roadmaps describes their attitude to constantly evolve action plans to be key players within the society sharper 2022 and 2023 will let citizens and researchers share this endeavour through engaging activities focused on the 5 missions of the horizon europe work programme sharper involves 14 cities in 8 regions across italy ancona camerino cagliari catania genoa macerata laquila nuoro palermo pavia perugia sassari terni and trieste through a diverse network of 9 consortium partners including universities research institutions museums social enterprises and more than 200 stakeholders from the civil society the cultural creative world industry research and education a special collaboration is developed with the education national system through association of teachers and regional educational offices the project will consolidate and innovate the experience developed over the last 9 years triggering researchers and citizens engagement across italy sharper has a solid european dimension through a collaboration with 7 erns in 7 countries to develop creative online contents and formats common strategies on impact assessment and researchers trainings sharper also collaborates with other nights in italy to share ideas communication and awareness actions
european technology and innovation platform bioenergy support of renewable fuels and advanced bioenergy stakeholders 20222025

the european technology and innovation platform bioenergy support of renewable fuels and advanced bioenergy stakeholders 20222025 etipb20222025 project aims at triggering collaborative efforts of stakeholders from research to innovation to implementation in the field of renewable fuels and bioenergy the project will support and empower stakeholders contributions to the green deal and the strategic energy technology setplan the european technology and innovation platfrom bioenergy etip bioenergy aims to actively engage with stakeholders and civil society link their needs to policy making of the european union and member states and to provide advice to industry the etipb20222025 projects objective is to support etip bioenergy in this task to achieve these objectives the project will facilitate steering committee and working group meetings for etip bioenergy provide information on research and innovation activities related technologies and policies on the etip bioenergy website engage with stakeholders from all involved sectors for information exchange and to provide a basis for etip bioenergy documents form citizens panels to develop citizens visions on the role of renewable fuels and bioenergy and develop policy recommendations specific features will include facilitating an update of the strategic research and innovation agenda sria a biofuels and bioenergy innovation challenge bbic a policy workshop two stakeholder plenary meetings spm and the development of a financial independence plan for etip bioenergy all activities will be widely communicated through newsletters social media postings and dissemination events
revealing the fundamental principles of picobodies with broadspectrum and redoxresponsive antibacterial activity

antimicrobial resistance is a burning global issue the available antimicrobials are losing efficacy as resistant bacteria arise but the industry does not invest enough into antibiotic discovery due to low expected revenues natural antimicrobial peptides amps hold great promise as blueprints for new antibiotics however there are few known natural amps with sufficiently high potency and low toxicity that enable applications in veterinary and human medicine as a result the research on natural peptide antibiotics has been obstructed new natural amps are needed urgently i propose for the first time that picobodies recently discovered peptides part of natural cow antibodies have potent antibacterial activity in contrast to known mammalian amps picobodies are exceptionally diverse due to the unique bovine immune system moreover all picobodies contain disulfide bonds that enable a redox regulation of their activity unlike common antibiotics i suggest that redoxactivated picobodies target bacteria in infection sites characterized by a reducing environment such as persistent bacterial biofilms in picobody i have 4 major objectives i interrogate natural picobody repertoires for antibacterial activity ii investigate if cows can develop antibacterial picobodies against essential bacterial targets iii understand how the redox environment regulates the antibacterial picobody activity and iv evaluate the activity of antibacterial picobodies using in vitro and in vivo models to achieve my goals i will employ a multidisciplinary approach based on protein science molecular biology microbiology machine learning and lab automation the project will establish key methods for the identification of antibacterial proteins reveal basic insights about the fascinating bovine immune system validate picobodies as previously unknown natural amps and open new research directions into the discovery of very much needed new peptide antibiotics
wiser wellbeing in a sustainable economy revisited

the focus on economic growth as an instrument to lead societies towards sustainable high wellbeing is increasingly problematic while gross domestic product gdp growth is slowing its environmental and social costs are increasing such that continued reliance on gdp growth entails a tradeoff between the wellbeing of current versus future generations in addition research shows that higher gdp generally hardly improves peoples subjective wellbeing to better support policy options our project aims to develop a new economic development framework that provides evidencebased and theoreticallysound policy insights on how to raise wellbeing of present generations leaving no one behind without sacrificing future wellbeing we will identify how gdp growth and productivity growth can be promoted and invested in wellbeing focusing on relationships that reconcile economic growth and sustainable high wellbeing while leaving no person and place behind we will analyze how these relationships work at different subgroup levels by explicitly considering gender perspectives and disadvantaged groups the projects multidisciplinary approach integrates knowledge from different disciplines combining quantitative and qualitative techniques to generate solid evidence our case studies will permit deriving important lessons from different regions of the world africa in particular moreover the relevance of our policy recommendations will be supported by insights from and interaction with stakeholders within the triadic goals of wellbeing sustainability and productivity the project looks for possible winwinwin pathways producing a new economic development framework that provides insight into how societies can use greater productivity to aim at greater human wellbeing policymakers will be helped by means of a dashboard and green book which provide guidance how to achieve sustainable growth and maximize wellbeing
dissection of the interactome and the regulatory network of the dualfunction transcription factor ying yang 1 a master regulator of plant stress responses and development

climate change and increasing exposure to environmental stress make adaptation and defence responses to one of the most significant factors for crop yield and quality at molecular level stressinducible master regulators and key transcription factors translate the stresssignalling into defence and developmental responses at the level of chromatin and gene expression the dual function transcription factor yin yang 1 yy1 is evolutionary conserved between animal and plant kingdom in arabidopsis the abainducible yy1 is a negative regulator and key component of aba responses contributes to the plant resistance to fungal infection and uvb radiation and controls flowering time some stress related functions of yy1 are conserved between arabidopsis and populus tree published and the preliminary data indicate that the stressinducible yy1 in arabidopsis is a hub that converts stresssignals into defence and developmental responses through interaction with transcription and epigenetic factors controlling common target genes however neither the proteinprotein interactome nor the direct target genes of yy1 were intensively investigated on the level of proteinprotein interactome of yy1 the comparison of published yy1flag ipms data with the preliminary y2h screen data did not find any overlap although both groups of yy1 interaction candidates contained transcription and epigenetic regulators these findings and theoretical considerations suggest that large parts of the dark interactome of yy1 wait still to be discovered regarding the direct target genes the proposed chipseq approaches are the first attempt to study yy1dna binding at a global scale the anticipated results will have a deep impact on understanding of the complex proteinprotein interactome of yy1 will identify the direct target genes of yy1 and will contribute to the development of applied approaches in crop plants that could benefit from optimised stress responses orchestrated by yy1
securing holistic and impactful food systems transformation with novel foods based on alternative proteins

the current food system is unsustainable and underperforming having high environmental and socioeconomic costs while still failing to ensure food and nutrition equity for all dietary shifts towards novel foods based on alternative protein sources nfap proteins derived from insect fungi bacteria micro and macro algae and agriculture and aquaculture byproducts provide a unique opportunity to reduce consumption of animalbased proteins potentially minimizing the impact of the food systems however knowledge regarding the environmental economic and social impact of the widespread production provision and consumption of nfap is very limited and not integrated into a holistic vision of the food system able to identify tradeoffs interaction between food system actors and second and third order impacts the goal of epicshift is to provide an unprecedented independent solid knowledge base on the sustainability env eco and soc aspects of nfap as options for protein diversification for human consumption considering that the contribution of each nfap types to reorganize the food systems may differ epicshift applies a quadruple helix innovation model in its multiactor approach to roadmap the sustainable development of nfap for planetary health diets designed as a thinktank and adopting food systems thinking approach epicshift will provide a multidimensional impact assessment of 7 nfap from protein type to product level at scale complemented with the necessary recommendations for food environments marketing regulatory approval infrastructure and investment needed to support longterm market growth epicshift integrated scenario analysis will further result in decision support tools that will inform policy and decisionmaking about the trajectories to achieve the sustainable integration of nfap in the eu diets ensuring resource efficiency food security and nutrition within a framework of just transition for all food system actors
vigilant maritime surveillance of critical submarine infrastructure

the european submarine networks are vital critical infrastructure for the eu member states this submarine cable and pipeline network is crucial for the european society and any failure or damage to it could potentially have an enormous effect on the societies due to the rapidly evolving threat and geopolitical landscape especially with incidents like the sabotage of the nord stream 1 and 2 gas infrastructure organizations overseeing critical infrastructure face significant challenges they must handle intentional threats while also grappling with growing problems caused by accidental and natural factors as well as climate change these issues can worsen the effects of deliberate actions to address these challenges effectively it is crucial for these entities to implement resilienceenhancing measures the aim of vigimare is to strengthen the resilience of critical infrastructure operators against threats to the european submarine critical infrastructure by developing testing and evaluating an innovative solution to enhance security and reduce risks of physical and cyberattacks on submarine cables and pipelinesthis will be accomplished by 1 mapping submarine systems surveying cables and landing stations and assessing vulnerabilities in the european submarine critical infrastructure network 2 develop an automated threat detection approach creating a realtime shared awareness of the surface above the submarine infrastructure to promptly indicate incidents to both critical infrastructure owners and member states authorities by integrating a comprehensive resilience ecosystem with real incidents at sea the project seeks to 3 identify early warning signals support analysis and pinpoint potential response activities to address physical cyber and hybrid threats the result will be enhanced resilience for submarine critical infrastructure owners supporting authorities to enforce the cer and nis2 directives implementation in the eu member states
eu visa diplomacy in world politics

the eu visa policy also known as the schengen visa policy relies on a positive list of thirdcountry nationals tcn exempted from visas to travel to the eu and on a negative list of tcn subject to visa obligations visa requirements play an essential role in international relations but are overlooked in the case of the eu whose visa policy has mostly been studied as a tool to limit irregular immigration this project visadiplo eu visa diplomacy in world politics consists in an innovative and comprehensive study of the making of the visa requirement lists it addresses a series of three research objectives the first objective is to map the priorities linked to eu visa diplomacy not only border enforcement but also trade tourism attractiveness energy supplies or sanctioning foes as the recent suspension of eurussia visa facilitation agreement demonstrates the second objective is to understand how these priorities are negotiated by the member states representatives in spite of concurring national interests the last objective is to question the distributional effects of eu visa diplomacy and bring evidence of the global travel inequalities resulting from eu visa requirements this project adopts an interdisciplinary approach drawing inspiration from migration diplomacy and sociology of the eu it relies on an original multimethod approach combining a quantitative study of the evolutions of visa requirement lists qualitative semidirected interviews with eu decisionmakers and geovisualization analysis since the findings on the unequal distribution of global mobility resulting from eu visa diplomacy will be represented in the form of an interactive map published and available online visadiplo aims to have a societal impact by bringing awareness and transparency to a policy whose opacity and negative impact on human mobility are often criticized
nature based solutions for atlantic regional climate resilience

the impacts of climate change on people planet and prosperity are intensifying many regions and communities are struggling to avoid losses and need to step up the effort to increase their climate resilience ongoing natural capital degradation leads to growing cost increased vulnerability and decreased stability of key systems therefore the european mission on climate adaptation acknowledges the need to adopt a systemic approach by working across sectors and disciplines experimenting and involving local communities nbracer steps up to this challenge with an innovative and practical approach to accelerate the transformation towards climate resilient regions that are safe green clean healthy and just adaptation will be based on the smart packaging of naturebased solutions nbs rooted in the resources supplied by biogeographic landscapes and embedded in a transformative action approach that mobilizes and enables regions and communities to accelerate forward nbracer works with demonstrating and replicating regions in the european atlantic biogeographical area to vision and codesign place based sustainable nbs that are at one with the regional landscapes upscaling these into coherent regional packages and building time and place specific adaptation pathways integrating local solutions and regional scales this process is supported by a regional scale effort to build adaptation journeys with community support with input from teams testing and validating place based nbs solution portfolios situated in landscapes innovative technical and adaptation transformation support packages provide quantitative mapping methods and a transformative action approach and capacity building and networking enable scaling out and building connections led by deltares advanced in climate adaptation science the consortium builds synergy from the strength of practitioners ecosystem engineers innovators of transformative adaptation finance and capacity building experts