Dragon09/odtu_chatbot huggingface dataset:
renewable and flexible fuel power generation technology enabling the multisectorial decarbonization with zero emissions

eu transport and power generation accounts approximately each for onethird of all co2 emissions from fossil fuel combustion while current decarbonisation measures are focused principally on two alternatives electrification and fuel switching these are not suitable for the hardertoabate sectors such as heavyduty road transport or decentralised energy production due to payload autonomy andor fuel supply requisites among other issues in fact these sectors still rely on fossil fuels for 94 of its energy needs constituting one of the main challenges to comply with the objectives of the paris agreement these sectors require a system that allows to exploit the advantages of the use of liquid fuels as are high energy density fast refilling and easy transport but bypassing the efficiency limitations and eliminating co2 emissions in addition to tackle the alarming increase of ghg emissions and the rise of global temperature it is necessary to deploy an effective solution in the shortmedium term therefore it is key not to depend on the construction of new infrastructures and be able to use the existing ones for the transport storage and supply of liquid fuels the main objective of allin zero is to develop a multifuel system to generate electrical and mechanical power with zero emissions this system will feed low zero or carbon carbonnegative fuels like ammonia natural gas biogas or alcohols into a compact membrane reactor producing a common intermediate temporary energy vector to be consumed in situ by power generation systems such as internal combustion engines and fuel cells allin zero will accelerate decarbonisation earlier than other technologies using available productive and supply chains soa technologies and upstream and downstream treatments for mobile and stationary solutions
dynamic throughspace interactions driven by molecular motors

different from the wellestablished theories based on throughbond conjugation throughspace interaction tsi has been proved to be another essential electronic interaction however it is still challenging to manipulate tsi and utilize it to develop organic functional materials due to the difficulties in conformational manipulation and the lack of structureproperty relationships of tsi hence this proposal aims to study the photophysical and electronic properties dynamic behaviors and working mechanisms of noncovalent tsi with the help of lightdriven molecular motors herein three objectives will be mainly investigated i a new type of molecular motor driven by the noncovalent conformational lock ii dynamic throughspace charge transfer and multistate luminescent switches iii singlemolecular junctions with dynamic tsi these objectives will be realized using experimental and theoretical combined strategies which broadly interconnect multidisciplinary techniques and knowledge the exploitation and dissemination are also involved in enhancing the expected outcomes and impacts of this proposal besides the experienced researcher er bears a strong background in photophysical chemistry tsi luminescent materials and theoretical calculation which is recognized by many awards and good publications the host lab and supervisor have been renowned for molecular motor photochemistry and dynamic chemistry for 30 years which has built a great experimental platform and scientific prestige including nobel prize for chemistry hence the twoway transfer of knowledge will be smoothly launched based on the complementary experience between the two sides in addition a series of training plans and public activities are proposed to promote the ers academic development career perspectives and employability a detailed work plan and risk management are also reasonably discussed to guarantee the feasibility and high coherence of the proposed work packages
the cultures of the cryosphere infrastructures politics and futures of artificial cooling

artificial cooling fundamentally shapes the world in which we live since the onset of the cold war cooling and freezing technologies have become increasingly vital for a wide array of everyday practices from nutrition health and reproduction to dwelling telecommunication scientific research and economic productivity a global system of cold storages cold chains and airconditioned spaces has become an energyintensive yet barely considered planetary infrastructure an artificial cryosphere artificial cold has drastically restructured life both on a biological and social level yet the farreaching impact of this technology is still largely unexplored and unresearched recent studies estimate that global cooling demand will increase fivefold by 2050 dramatically exceeding our future energy budget and urgently calling for change cultcryo argues that avoiding the impending global cooling crisis will be impossible if we do not understand how the planetary infrastructure of artificial cold is deeply interwoven in cultural practices thus in order to analyze the constitution of cryogenic cultures we will undertake four interdisciplinary multisited case studies in the domains of food supply air conditioning biomedicine and computing we develop innovative approaches using mixedmethods rooted in the history of technology geography digital history of concepts ethnography and the philosophy and ethics of technologybreaking ground for an innovative interdisciplinary field of research cultcryo will provide the first geographical mapping of the cryosphere a historical reconstruction of its emergence an ethnographic account on its cultural constitution and a philosophical analysis and ethical assessment of its underlying norms and values thereby we develop a corpus of urgently needed knowledge to critically analyze a pressing global phenomenon while also identifying alternatives towards a more sustainable future of artificial cold
advanced photonic processes for novel solar energy harvesting technologies

approach is a multistakeholder project aiming at democratizing the opportunity for postacademic training and professional development of young researchers and innovators approach is a partnership that will enable the enhancement of talents inventive thinking and creative knowledge in the development of nanofabricated materials and methods for solar energy harvesting applications it will contribute to the growth of diversity of backgrounds talents and motives of job expectations while will allow scientific knowledge advances through interaction and exchange of views approachs basis of sustainable development has four dimensions merit attention a placing knowledge including highlevel scientific knowledge at the service of development b converting knowledge in all its forms into value via applications and impact assessment and c sharing good practice to ensure widespread benefits and d importantly apply a holistic talent development approach moreover approach aims to push forward the application and potential exploitationvalorization of the forth upol pdot novinano and tsnuk knowhow through strong collaboration and welldesigned research activities among the partners topclass experts in the field of applied research and talent development like imec solaronix and vamk will provide training courses as well as handson experience and ondemand training to young researchers originating from these widening countries exchange of both young researchers and topclass experts is crucial for the successful realization of the proposals objectives as an end product this collaboration will set the widening partners as players of excellence in the development of advanced photonic processes for novel solar energy harvesting technologies
nuclear powered hydrogen cogenenaration nphyco

the objective of this proposal is to investigate the feasibility and viability for existing nuclear power plants npps to generate large amounts of hydrogen for supporting the decarbonisation goals of the eu as the eu aims to be climateneutral by 2050 moreover this feasibility study aims to prepare the realization of nuclear hydrogen generation projects in the short term 2025 thereby three major fields will be investigated1investigation of the technical economic and operational feasibility2development of configuration for a pilot project3selection of pilot plant sites for implementation phase 2025the superior goal of the nphyco project is to prepare a definite nuclear powered hydrogen cogeneration project with a short implementation horizon this will be achieved by a comprehensive assessment of the technical feasibility and the commercial reasonability the investigations will be focused on existing h2 generation technologies and existing and willing npp to be able to implement a nphyco project within a 3year time period after completion of this projectthe nphyco project aims to gain knowledge concerning the coupling of npp plants and newly built h2 plants the project will propose an optimal degree of integration to maximise mutual benefits based on mutual integrity of both plantsthe results will be summarized in practical decision matrixes guidelines and checklists these results can be used by npp operators h2 generation epcs and all other stakeholders such as investors safety authorities notified bodies and h2 consumers for their decisionmaking processes
an integrated platform of novel cost and energyefficient conversion technologies producing liquid and gaseous biofuels from sustainable biogenic residues validated for direct use in fuel cells

advanced biofuels represent an important piece of the puzzle in the eus quest for climate neutrality as they contribute to decarbonising transport sectors and decrease the eus dependence on fossil fuels fuelsc aims to contribute to this quest by increasing the availability of two liquid and two gaseous advanced biofuels for maritime and road transports produced from biogenic organic wastes and co2 fuelsc will develop an integrated platform of innovative energyefficient conversion technologies validated at trl5 including bioelectrochemically assisted ch4 production bioelectrochemical nh3 production gasification microbial electrosynthesis and electroreduction various biogenic residues biodegradable and nonbiodegradable will be converted under mild conditions into ch4 nh3 formic acid and ethanol by two main production routes using renewable energy thereby enabling efficient energy surplus storage as chemicals the 4 biofuels can be used as dropin but fuelsc will also test them in fcs for electricity production gaseous nh3 and ch4 in sofcs liquid ethanol and formic acid in dlfcs power density energy efficiency and stability of each process will be validated the technologies will be modelled at process level for the description of interfacial phenomena and at system level leading to an integrated processes digital twin this second model together with a feedstocks mapping tool will provide relevant data for circularity assessment cost calculation benchmarking and replication in other relevant use cases this is expected to create new businesses opportunities and strengthen the eus leadership in science and technology and in the biofuels market fuelsc gathers an interdisciplinary consortium composed of eus prominent rtos and universities a large industry providing feedstocks and four smes contributing to market uptake and global outreach it will be supported by an international advisory board providing strategic advice
novel hybrid electroanaerobic digestion system for simultaneous antibiotics removal and bioenergy recovery

the overuse or misuse of antibiotics has caused new pollution challenges and the development of antibiotic bacteria anaerobic digestion ad is sustainable biotechnology that can couple waste pollution control and bioenergy methane ch4 recovery however ad fails to achieve satisfactory antibiotic removal due to the low concentration and low biodegradability of antibiotics and the high toxicity of antibiotics on microbial activity to address these scientific challenges in this project we aim to develop a novel hybrid electroad system by coupling the application of external voltage and the addition of activated carbon for the enhancement of antibiotic removal and renewable bioenergy recovery the novel hybrid electroad system will synergistically incorporate high adsorption capacity by activated carbon high biodegradability of antibiotics by bioelectrochemical reduction and high methanogenic activity mediated by extracellular electron transfer eet an excellent array of multidisciplinary methods incorporating electrochemistry bioinformatics and molecular biology will be applied to achieve this objective and unravel underlying mechanisms of enhanced eet and antibiotics removal the results will further create new knowledge of microbial ecological function in ad and advance the application of anaerobic technology to crucial environmental protection scenarios combining my background with the training of advanced instruments offered by the host dr guangxue wu at nui galway and expertise in quantifying trace compounds from the secondment dr konrad koch at tum this project will lead to the realization of new anaerobic biotechnology that can achieve simultaneous energy recovery and efficient antibiotic removal contributing to scientific societal and economic impacts being an independent investigator of this project this fellowship will provide an excellent chance for me to become an independent research group leader in my future career
fast easy diagnostics for personalised phage therapy

personalised phage therapy using magistral preparations of phages is among the most promising solutions to fight antimicrobial resistant infections but this approach requires a rapid diagnostic that identifies the pathogens involved in the infection and the phages active on them vsale bioscience has developed the phagogram the first automated invitro diagnostic tool that enables a fast determination of bacteriophages suitable for treating a particular bacterial infection it consists of a basic test kit a disposable well plate with reagents a highperformance luminometer and a dedicated software that proposes the best matching phage cocktail to treat the patient compared to the current diagnostic methodologies which take up to 47 days the phagogram compares the activity of up to 96 phages on a bacterial culture within 23 hours making phage susceptibility testing accessible for hospital microbiology labs and enabling personalized therapy on a routine basis
developmental crosstalks between microglia bloodbrain barrier and maternal microbiota

brain functioning can be influenced by body ecosystem signals conveyed through the vasculature and regulated by the bloodbrain barrier bbb a selective and modulable barrier that controls which substances and cells enter the brain structural or functional bbb deficits are found in many brain diseases from neurodevelopment to neurodegeneration thus understanding how the bbb develops holds critical significance for both biologists and clinicians yet we still lack fundamental knowledge on how interactions between different cellular populations in coordination with environmental signals contribute to bbb construction during early developmentto tackle this issue we will focus on the core components of the bbb pericytes and endothelial cells and microglia the brain resident macrophages microglia play key roles in circuit assembly and we have shown that prenatal microglia which are in close apposition to the vasculature respond in a sexspecific manner to signals derived from the maternal microbiotahere we will study the developmental crosstalk between microglia and bbb in both male and female embryos by investigating i how pericytes influence prenatal microglia ii the spatiotemporal heterogeneity of bbb closure and implication of microglia and iii the impact of maternal microbiota on bbb formation and crosstalk with microglia our approach leverages multidisciplinary and stateoftheart techniques in newly developed murine models of microglia depletion and in utero antibiotic treatment including twophoton live imaging singlecell and spatial transcriptomics in vitro bbb model and comparison to human embryos ultimately we will establish an integrated framework of bbb formation and bbbmicroglia interplay shedding light on how signals from maternal microbiota shape brain development our findings will provide key insights into normal and pathological brain wiring paving the way for the identification of potential therapeutic targets
stimulating innovation experiments in food processing live demonstrators

sixfold unites partners from the smart sensors 4 agrifood partnership and its network of living labs with a clear aim stimulating innovation experiments in food processing live demonstrators the twin transition stands at the heart of the green deal and farm to fork strategy the agrifood sector plays a critical role in the realisation of these ambitions the nature of deep tech innovation also shows the need for a transition via responsible regulatory frameworks living labs are looking for more experimentation by engaging societal stakeholders and addressing innovation barriers experienced by agrifood companies sixfold aims to facilitate implementation of deep tech within the agrifood sector by building a robust network of living labs across the eu this network will support a dynamic and regionally embedded ecosystem thriving with deep tech innovations relevant for the agrifood industry such as ai and machine learning robots and cobots biotech etc throughout the food system the timing is critical for agrifood companies to experiment with innovative technologies and collaboration with deep tech innovators sixfold builds on an existing framework nevertheless a careful assessment of the current state of play through interviews and study visits is made after which assessed barriers to innovation is tackled by a tailormade cocreation process this ensures maximum participation of external experts regulators and broader societal actors on regional and european levels and in turn generates a more complete and validated action plan adapted to realworld needs the network of living labs will in this way facilitate collaborative knowledge exchange by actively engaging stakeholders from various regions and ensuring inclusivity and diversity in participation amongst other objectives the updated operational handbook of the network of living labs will form the basis of a successful transition towards sustainable food systems across europe
the sequencing microscope a path to look at the molecules of biology

the goal of biological research is to understand how life works although progress is fast there seems to be an infinity of things we do not understand when it comes to understanding tissue from the bottom up our knowledge leaves much to desire feynman claimed that it is very easy to answer many of these fundamental biological questions you just look at the thing well the problem is that looking at the thing is the problem microscopy might never give us the possibility to directly see dna or rnasequence for this the community has evolved extraordinarily powerful sequencers today one man can routinely read millions of sequences on a weekly basis and likely soon we will read billions of sequences daily in small labs but this in itself will not allow us to just look at the thing we argue in this proposal that by using the sequencer itself as a microscope we will get that much closer to actually see what is going on in biological systemsresearchers have started in this direction by coupling microscopy and sequencingdata from the same sample but that is a temporary solution here we propose a technology for inferring images using sequencing data alone bypassing the need for advanced microscopy and leveraging the potential of the exponential growth of sequencing technologywe use dna seeds and perform a reaction insitu that allow these seeds to copy themselves locally this is analogous to phylogenetic reconstruction but instead of inferring ancestry we infer relations of amplicons to spatial locations in tissue by using a unique approach we derive spatial information connected to rna transcript information directly insitu allowing for a nontargeted spatial transcriptomics technique that is as simple as running a pcr when successful this approach will then enable us and others to learn the inner secrets of biological system at a significantly faster rate
advancing sustainable agriculture through offgrid energy and cooling solutions in africa

large parts of subsaharan africa have no or only limited access to the electricity grid therefore many farmers cannot adequately cool their product this results in an enormous loss and waste of food which is responsible for more than 10 of total anthropogenic greenhouse gas emissions worldwide cooling the food by inefficiently using generators on fossil fuels the most common alternative is not climate friendly eitheragricool will address both problems with a containerized solution in which food can be stored and cooled it combines the use of photovoltaic technology thermal energy storage by phase change materials chillers and smart control strategies to offer an affordable scalable and climate friendly solutionthe agricool system will be demonstrated in rural communities in south africa cape verde somalia and zimbabwe to showcase its adaptability to different climatic conditions a life cycle assessment following the cradletograve approach will be conducted to show the systems impact on environment and paris targets compared with competing approaches a comprehensive market and business strategy will be developed for adoption of the system after the project training programs for farmers technicians and engineers that are tailored to local conditions will ensure that the system can be installed operated and maintained locally lastly an advanced course for third party engineers from various african countries will be organized on the design customization and broader economic and social aspects of the systemagricool is going to empower rural african communities and industries by enhancing food security reducing waste and fostering economic growth while contributing to achieve the african countries targets of the paris agreement a balanced consortium with about the same share of person months and budget for african and european partners ensures that african problems are tackled by solutions tailored to african conditions