Dragon09/odtu_chatbot huggingface dataset:
erachair in tree bioengineering

advancing biotechnological innovation in the forest biorefining sector is crucial for europe to meet climate objectives and driving the shift towards a carbonneutral economy however challenges such as preserving natural forest ecosystems and promoting sustainable development practices offer opportunities for growth recent geopolitical events like the russian invasion of ukraine highlight the need to explore alternative supply chains and build industry resilience the decline of the fossilbased industrial region in northeast estonia acts as a catalyst for transitioning towards forest biorefinery solutions prompting proactive measures to address environmental concerns and historical pollution from past mining activitiestreebiotec will innovate alternatives led by prof jaakko kangasjrvi an era chair holder by establishing a research group for tree bioengineering at the institute of bioengineering ut this initiative aims to enhance photosynthesis growth rates and resilience of birch trees fostering reforestation carbon capture and soil bioremediation of contaminated mining areas for the wood industryfurthermore treebiotec strives to capitalize on public interest in bioengineering through a public awareness campaign engaging stakeholders and fostering dialogue on biotechnological advancements leveraging geographic proximity and industry connections between estonia and finland the project cultivates a collaborative ecosystem accelerating bioengineering effortsadditionally the initiative fosters creativity by drawing inspiration from programs like gingko bioworks creative residency collaboration among scientists architects landscaping artists and experts will create an innovative living laboratory exploring bioeconomy solutionsthrough treebiotec the institute of bioengineering positions estonia as a leader in forest biotechnology catalyzing advancements and fostering collaboration to address global challenges
poparch the role of population scale genetic variation in chromosome 3d architecture

the linear onedimensional 1d dna fiber inside each eukaryotic cell nucleus folds into a precise threedimensional 3d structure whose structural preservation is vital for correct cell homeostasis and generegulatory mechanisms previous studies showed that if 3d structure is altered aberrant phenotypes and diseases can arise however little is known on how 1d variation can affect 3d genome variation although recently developed technologies allow researchers to generate data to characterize the 3d structural patterns as of yet no studies have systematically examined how this affects interindividual 3d variation i hypothesize a substantial fraction of 3d genome structural variation is controlled through 1d variation affecting gene expression and lastly phenotypes i will test this by quantifying 1d and 3d genomic variation from 100 individuals selected from a chicken cohort my host raised under extremely wellcontrolled environmental conditions making it the largest study of its kind up to today and the first to use an in vivo animal model then computationally i will develop an analytical framework and produce a catalog of dna sequence variants that condition 3d genome structure upon executing my research i expect to provide a new explanation on how noncoding dna variants can exert their effect thus offer new testable hypotheses to researchers interested in genotypephenotype transitions this is a proofofconcept project and should i be correct will open a door to expansion in other species including humans with a large potential use in medical genomics thus facilitating pharmacological interventions by disentangling causal intermediate processes by combining my 3d genomics expertise with the hosts populationstatistical genomics knowledge on his unparalleled cohort of chickens i will develop unique expertise to place me as the pioneer of a completely new multidisciplinary field
signit signacula in roman and postroman italy marking religious and cultural identity 2nd11th c ce

the signit signacula in roman and postroman italy marking religious and cultural identity 2nd11th c ce project aims at studying the cultural history of the italian peninsula from the roman imperial period to the central middle ages by means of the objects known as signacula ie matrices bearing text signs andor iconographic motives designed to stamp various materials linguistic choice is one of the main markers of identity thus the project focuses on materials found or originally coming from a sample of italian regions featuring both latin and greek speaking communities veneto emiliaromagna campania apulia calabria sicily and sardinia the historical value of this body of evidence has been hitherto largely neglected due to its difficult dating to overcome this issue i will study for the first time the corpus as a whole from antiquity to the middle ages the projects objectives are threefold firstly to establish a clear dating protocol for the signacula to unlock their full potential as historical sources secondly building on the newlydated material to study the evolving linguistic patterns and their contribution to the making of specific local identities between antiquity and the middle ages thirdly to track over the longue dure changes in marking practices and to analyse them as proxies for cultural transformations to achieve these goals i will build up an openaccess database gathering published and unpublished signacula pertaining to the chronological and geographical framework under scrutiny the databases structure will allow both qualitative and quantitative analysis of the material and will facilitate comparisons with other types of stamped writing and of inscribed objects eg seals by adopting and building upon the technical features and norms of the text encoding initiative standard tei httpsteicorg developed for the digital edition of ancient inscriptions epidoc and seals sigidoc
norwegian romantic nationalisms

norn seeks to uncover both the affective and ideological dynamics of romantic nationalism examining how collective emotions related to the idea of the nation were harnessed activated and constructed through literature and theater using norway as a case study norn forges a highly innovative approach combining cultural studies affect theory critical race studies and reception studies with qualitative methods taken from literary studies and history as well as quantitative methods from the digital humanities in order to achieve three interconnected objectives 1 a comprehensive modeling of nineteenthcentury norwegian literature using machine learning 2 a metacritical reassessment of literary historiography as an explicitly romantic nationalist project and 3 a radical reevaluation of the impact of transnational romantic performance culture on nationbuilding norn approaches romantic nationalism from two distinctive perspectives on the one hand the project seeks to understand the affective register of romantic nationalism qualitatively which entails meticulous investigation of a wide range of sources through an innovative combination of theoretical lenses in order to recontextualize it as what raymond williams famously called a structure of feeling on the other hand norn profoundly decontextualizes the literary works themselves through socalled distant reading methods carrying out an ambitious computational modeling of the entire nineteenthcentury literary field this will enable an interrogation of prevailing master narratives about periodization and processes of inclusionexclusion delineating romantic nationalism based on far more transparent criteria than those that underpin traditional literary historiographical methods
enhancing safety of liquid and vaporised hydrogen transfer technologies in public areas for mobile applications

international standards related to cryogenic hydrogen transferring technologies for mobile applications filling of truck ship stationary tanks are missing and the experience is limited or nonexistent elvhys aims to provide indications on inherently safer and efficient cryogenic hydrogen technologies and protocols in mobile applications by proposing innovative safety strategies including selection of effective safety barriers and hazard zoning strategies which are the results of a detailed risk analysis this is carried out by applying an interdisciplinary approach and conducting experimental theoretical and numerical studies both on the cryogenic hydrogen transferring procedures and on the phenomena that may arise from the loss of containment of a piece of equipment containing hydrogen unique investigations on i cryogenic hydrogen transferring operations for selected mobile applications ii equipment and materials response to liquid hydrogen lh2 transfer and incident roots as well as iii releases combustion and explosion phenomena will be pursued for the first time a study on the frequency of failure of lh2 transferring equipment will be carried out by exploiting the internal databases of some of the consortium partners which contain valuable information collected in the last decades in addition critical and exclusive data on innovative safety barriers eg emergency release device under development will be shared by air liquide partner beyond knowledge on cryogenic hydrogen transfer gained in several years in this fashion critical inputs can be provided for the development of international standards by creating safe and optimised procedures and guidelines for cryogenic hydrogen transferring technologies the results of elvhys will contribute to many objectives of the clean hydrogen ju sria such as increase the level of safety and support the development of regulations codes and standards for hydrogen technologies and applications
targeting telomeric dna damage response as a new strategy to fight immunosenescence and improve vaccine response

the immune system is remodeled with age going through a series of changes known as immunosenescence including the involution of primary lymphoid organs the contraction of the immune repertoire a progressive lineage skewing towards the myeloid lineage and a lowgrade proinflammatory status a consequence of immunosenescence impacting the morbidity and mortality of infectious diseases is a dramatically reduced vaccine response in the elderly thus reducing the burden of immunosenescence has the potential to impact the effectiveness of vaccine response an established hallmark and driver of ageassociated functional decline is telomere dysfunction dysfunctional telomeres are actively transcribed to generate telomeric noncoding rnas tncrna which are essential to recruit dna damage response ddr factors at damaged telomeres thus fueling ddr and causing cellular senescence initiation and maintenance sequencespecific telomeric antisense oligonucleotides tasos target these tncrnas and effectively inhibit ddr activation ameliorating agerelated phenotypes in mouse models the telomerasedeficient terc mouse model causes telomere shortening and dysfunction recapitulating features of immunosenescence immune system reactivity reduction decreased long term renewal of hematopoietic stem cells and lymphocytes numbers increased neutrophil count tasos treatment has beneficial longterm effect in this model by decreasing immunosenescence and counteracting inflammation we now plan to test the efficacy of tasos treatment on rejuvenating the immune system of aged wild type mice a physiological setting for aging the final goal will be to assess if tasos impact on vaccine response in both models young terc mice and aged wt mice in summary we plan to determine the efficacy of tasos to improve immune responses including vaccines in the elderly
nimble artificial intelligence driven robotic solutions for efficient and selfdetermined handling and assembly operations

over the last years production has been shifted from mass production to customization the conventional production lines traditionally focused on one product variant or one family of products do show their limitations to cope with the new needs moreover unprecedented worldwide events such as the recent pandemic crisis indicated even more the need for flexible production systems that can rapidly switch production to a totally different one eg automotive manufactures had to produce respirators facemasks etcas a response masterly aims to develop flexible robotic solutions constituting of modular grippers combined with stateoftheart robotic technologies such as mobile high and low payload industrial and collaborative robots and smart cranes enhanced with ai driven advanced control and perception capabilities that will allow them to act autonomously handling a large variety of parts varying in size shape and material while being acceptable by both genders of workforce the developments will focus around the following 5 pillars1 innovative efficient and low consumption systems for storage retrieval conveying and pickandplace using a multidisciplinary approach combining technologies 2 robust handling devices and systems with integrated ai driven advanced control3 userfriendly interfaces for robotmachine control and programming4 interoperable sw and hw interfaces 5 industrial pilot cases for work piece handling in full production linethe technologies will be tested for flexibility efficiency user acceptance in three use cases from different productions sectors aiming to demonstrate production line and cross sector applicability and adaptability elevators manufacturing focusing on the assembly of electrical cabinets of lifts kleemann sportswear focusing on warehouse logistics and packaging decathlon and aeronautics production focusing on production of large composite panels of aircraft wings aernnova
transdisciplinary and deliberative equity appraisal of transition policies in energy and mobility

numerous attempts of implementing transition pathways across europe illustrate the difficulty of designing policies that combine efficient climate action and justice considerations one reason is that the socially diverse and thus also geographically dispersed demands and vulnerabilities of potentially affected groups do not appear as a wellstructured input at any stage of the policymaking process therefore tandem will test an innovative transdisciplinary approach in five different case studies in spain belgium finland poland and austria that address controversial transition policies in energy and mobility affecting urban and rural populations the tandem project aims to design a methodology allowing policy makers to create and implement inclusive and just transition pathways by involving potentially affected citizens public authorities the private sector and other relevant stakeholders it relies on combination of accessible and complementary methods deliberative visioning build on artbased approaches system mapping assessment and appraisal methods these methods constitute the backbone of a series of three deliberation panels with citizens in these panels tandem invites participants to create their visions perspectives and narratives on just transition policies and to define their own criteria and interventions this deliberation process will guide a systemic impact assessment that will inform individual appraisals of the interventions public authorities will be involved at the beginning and end of each panel to provide insights on political social and economic factors that should be taken into consideration furthermore private companies will be invited to participate through interviews and surveys tandem will thus develop a transdisciplinary approach to identify and analyse emerging inequalities of lowcarbon transition policies as well as to codesign socially fair and effective alternative transition pathways with stakeholders
modelling text as a living object in crossdocument context

interpreting text in the context of other texts is very hard it requires understanding the finegrained semantic relationships between documents called intertextual relationships this is critical in many areas of human activity including research business journalism and others however finding and interpreting intertextual relationships and tracing information throughout heterogeneous sources remains a tedious manual task natural language processing nlp fails to adequately support it mainstream nlp considers texts as static isolated entities and existing approaches to crossdocument understanding focus on narrow use cases and lack a common theoretical foundation data is scarce and difficult to create and the field lacks a principled framework for modelling intertextualityintertext breaks new ground by proposing the first general framework for studying intertextuality in nlp we instantiate our framework in three intertextuality types inline commentary implicit linking and semantic versioning we produce new datasets and generalizable models for each of them rather than treating text as a sequence of words we introduce a new data model that naturally reflects document structure and crossdocument relationships we use this data model to create novel intertextualityaware neural representations of text while prior work ignores similarities between different types of intertextuality we target their synergies thus we offer solutions that scale to a wide range of tasks and across domains to enable modular and efficient transfer learning we propose new documentlevel adapterbased architectures we investigate integrative properties of our framework in two case studies academic peer review and conspiracy theory debunking intertext creates a solid research platform for intertextualityaware nlp crucial for managing the dynamic interconnected digital discourse of today
characterization of multispecies bacterial interactions underlying the beneficial symbiosis of a mediterranean squid

animals often use associations with microbes to preserve their health these mutualisms are maintained by hostmicrobe communication and though interactions between bacterial symbionts the squidvibrio symbiosis has been used for over 30 years to study beneficial hostmicrobe associations however nearly all studies of the symbiosis have used euprymna scolopes and its only symbiont vibrio fischeri which precludes examination of how multiple microbial species affect symbiosis using the squid sepiola affinis and its two symbionts v fischeri and vibrio logei the squidvibrio project proposes to examine the effects of multiple microbial species within a mutualism the project is organized into three objectives 1 implement a husbandry facility for s affinis 2 quantify the symbiont populations within the s affinis light organ over seasons and over maturation 3 identify how the symbiont populations alter metabolites within the light organ first a husbandry facility will be established at the banyulssurmer oceanographic observatory that will allow for the maintenance of wild s affinis and for rearing of the squid second metagenomics will be used to estimate the proportions of v fischeri and v logei within the light organ subsequently light organs of fieldcaught and reared squid will be imaged using confocal microscopy to identify if the vibrio spp inhabit mixed or distinct niches the third objective will use lcms and mass spectrometry imaging to identify metabolites that are altered by each vibrio spp and how localization patterns of these molecules are affected these methods will allow for the twoway transfer of knowledge with the researcher providing squid husbandry techniques and the host institution providing genomics and metabolomics the squidvibrio project will establish s affinis as a model organism in europe that can provide insights into how symbionts interact both with each other and their host to underly a mutualism
from big data to new science and practical solutions

from big data to new science and practical solutions data4healthcare is a novel postdoctoral programme hosted at an international and multidisciplinary research environment of university of oulu uoulu finlandthe data4healthcare addresses the great demand for specialists in all fields who are capable of working with different types of massive datasets understand different datasources and legislation related to the demand of turning them into useful information for decision making in healthcare this is achieved by tackling some of the most important scientific problems by collaborating intensely with experts from different disciplines and stakeholders and educating wellqualified postdoctoral researchers to meet the requirements of the 21st century data4healthcare trains 25 postdoctoral researchers to better exploit and develop the possibilities of big data in the eu and globally the aim of the data4healthcare programme is to offer cuttingedge research research training and career development for experienced researchers of any nationality in fields associated with big data data analytics machine vision and artificial intelligence the oulu ecosystem with worlds smartest hospital strong background in ehealth and ict for example 6gflagship as worlds first 6g research programme to develop the future of wireless communication technologies research teams utilizing large molecular data expertise in artificial intelligence and several companies locally and in collaboration offers unprecedented surroundings for the programme the identified primaryfocus themes of research in the programme in uoulu are data as new resources in the society health data management practices in rdi collaboration technical tools in data management and processing
addressing sustainability transition pathways in the blue economy

oceans are a lifesupport system for human societies they supply fundamental goods such as fish food materials energy and provide benefits associated with our wellbeing they form cultural values and contribute to jobs creation and trade the development of national ocean development plans combined with blue growth bg strategies are turning the ocean into a new frontier of industrial development in fact the eus blue economy produces a turnover of 750 billion euroyear however the actual sustainability of this blue acceleration process remain to a large extent uncertain due to 1 an unclear interpretation of the concept of blue growth across different policies the 2 multiple human pressures across scales and marine regions cause ecological degradation with high social costs and 3 the lack of integrated methodologies that can capture the effects of the bg trends on oceans health and human wellbeing over spatiotemporal scales there is an urgent need for interdisciplinary approaches that can address the pathways of sustainable transitions in marine realms and the deriving benefits and costs to society and the environment bluepaths aims to 1 develop an integrated humanocean framework for bg