Dragon09/odtu_chatbot huggingface dataset:
development of late medieval stonecut vaults an invisible bridge between east and west

this project aims to explore potential connections between medieval stonecut vaults in the middle east and similar vaults that suddenly emerged in european regions such as the valencian kingdom northern germany and southern italy between the 15th and 16th centuries the research endeavours to enhance our understanding of the geometric analysis design and construction techniques employed in these highly intricate vaults while modern stonecutting forms had yet to develop in europe a constructive and decorative technique that anticipated existing solutions in western christian culture had evolved in the middle east in this context the study will progress by examining examples found in eastern countries such as armenia turkey israel and egypt which clearly exhibit construction similarities with europe within this framework the geometric analysis of five of the most complex vaults of the era will be conducted and these vaults will be practically reconstructed the existing knowledge has predominantly relied on sources and appears inconsistent in some aspects the innovative approach of this project involves formulating hypotheses about vault design supported by data obtained directly from constructed objects a method not commonly used until now in this context by comparing the current interpretations of existing sources with the results of field and workshop studies it will be possible to examine similar structures based on a scientific foundation thus allowing for the establishment of new connections between christian western and muslim eastern can be established through the history of construction furthermore the research findings are expected to make a significant contribution to the preservation and restoration of cultural heritage
arctic pollution in a one health perspective from complex challenges to sustainable solutions

the arctic is undergoing rapid changes multiple stressors such as climate change and pollution from local and remote sources affect human life wildlife and the ecosystems of the arctic these are inseparably connected and require a holistic approach to analyses and assessments of pollution issues and to their solutions using this one health approach arcsolution will provide knowledge and mitigating solutions cocreated with the people of the arctic the arctic is home to a variety of arctic communities to capture this diversity arcsolution will work in four arctic locations ie northern finland svalbard northern norway troms and greenland integrating local and indigenous knowledge with environmental health technical and social science research in a one health approach the one health framework will be instrumental in identifying knowledge and data gaps and in synthesizing the information generated and collected in arcsolution in addition to scientifically relevant priority pollutants eg perpolyfluorinated alkylated substances mercury microplastics and their additives and key pathogens arcsolution will provide room for research and citizen science projects on locally prioritized issues we will study pollution from local and remote sources in a climate change context pollutant accumulation in food webs and human exposure we will also evaluate current and predict future impacts of these pollutants on arctic ecosystems and human health together with the local communities we will develop solutions in the fields of circular economy technology and chemicals management our results will be used in education programmes at arctic schools already connected to arcsolution they will be communicated to policymakers industry and the scientific community the one healthbased knowledge will strengthen the knowledge base and contribute to sustainable preventive actions for human life wildlife and the ecosystems in the arctic
european doctoral network for neural prostheses and brain research

donut european doctoral network for neural prostheses and brain research has the mission to provide a multidisciplinary and intersectoral network for young talented researchers the ambition of the project is to serve as a springboard for the expansion of eu partners into the fastdeveloping braincomputer interface bci technology and connected scientific disciplines the dn will leverage the complementary expertise of 7 academic beneficiaries and 8 associated partners from 8 eu countries to guide its 10 doctoral candidates dcs to address and solve deep problems in brain research development of different bci applications and systems with the latest technological advancementsthe proposed dn will integrate existing research in bci systems to make it more userfriendly suitable for different types of potential endusers and for modern medical diagnostics the dn would also provide excellent opportunities for career development of young researchers under the umbrella of german doctorate graduate school pk nrw graduate school for applied research in north rhinewestphalia with over 180 participating professors regularly offering specialised trainings and courses including scientific research writing academic presentation skills etc early scientific independence is one of key goals of training programmesit is the ambition of donut to build a strong and lasting network not only between the dcs but also between the participating beneficiaries and associated partners donut researchers will benefit of a dense network of contacts with scientists acquired during networkwide training events to improve their career prospects in the european and worldwide innovation sector having the opportunity to become scientists employable in both the industrial and academic sectors the participation of 7 industrial participants in research and training programmes will guarantee extensive intersectoral experience for the trainees and maximise the impact
smart avionics for flight termination systems safest

safest contributes to the european capability to provide independent reliable and efficient solutions in the global space transportation market the project will lead to a demonstrator of a modular autonomous flight termination unit aftu for microsmall launchers validated in a representative flight processor execution and emulated environment dynamics reaching trl 56 this solution will differentiate from other developments tightly linked to a specific launch site safety regulation and oriented cost and mass to institutional launchers the proposed aftu segregates the generalpurpose sensors and functions eg localisation from the mission abort rules which are launcher and spaceport dependant allowing customisation for a given launcher and site this strategy is deemed a game changer for the reduction of launch service cost availability flexibility enabling a more responsive access to spaceadvanced lowcost and modular avionics solutions safest proposes to mature up to trl 56 an mpsocbased sw execution platform for modern avionics avionics and gnc sw development involve highly demanding tasks calling for powerful computational resources a sw execution platform is proposed hw independent multilayered and highly decoupled smart integrated avionics mia it will bring the following benefits increased performance several cores increased flexibility modular architecture easy 3rdparty integration os hw abstraction and reduced cost cots components new methodologies fully oriented to reusability and appstore conceptintegration of both technologies into a single solution the integrated set will demonstrate that a modular aftu design despite its highly demanding computational load can be implemented in a modular architecture and sw development environment
exploring the landscape of biomolecular condensates in enterovirus infection

the genus enterovirus comprises many important human pathogens eg polio coxsackie and rhinovirus that cause a wide array of diseases ranging from mild to lifethreatening as there are hundreds of enteroviruses and vaccination to all of these is not feasible there is an unmet need for panenterovirus antiviral drugs hence we need to deepen our knowledge on the enterovirus life cycle and virushost interactions mammalian cells express an arsenal of sensors that function to restrict virus replication and spreading these include rigi and mda5 which recognize viral rna and trigger expression of type i interferon ifn and pkr a kinase that upon recognition of viral rna blocks translation and triggers the formation of membraneless condensates socalled stress granules sgs that serve as platform for rigi and mda5 signaling on the other hand viruses have developed sophisticated mechanisms to suppress antiviral responses the enterovirus 2a protease 2apro has been recognized by the host lab to antagonize sg formation and ifngene transcription emerging evidence points towards the existence of many more types of condensates with a role in antiviral signaling such as pkr clusters rnase l bodies and cgas foci unfortunately comprehensive insight into the composition formation and dynamics of these condensates in infected cells are missing in this project i aim to comprehensively characterize antiviral condensates in cells infected with wildtype enterovirus or a 2apro inactive mutant i will use stateoftheart microscopy approaches including an assay that was recently developed by the host lab and that allows realtime visualization of the viral life cycle besides i will assess the role of condensates as signaling platforms that connect stress sensors with effectors of the innate immune response in infected cells this project will provide insights into enterovirushost interactions and may uncover new targets for antiviral therapy
euau partnership for resilient inclusive and safe food systems for everyone

the uprise euafrican union au project integrates food safety practices associated to mycotoxin contamination into all aspects of food production distribution marketing and consumption in the au and provides tangible tools and strategies to enhance inclusive participation in the improved african food safety system afss at the local national and regional level uprise activities are aligned with the current au food safety strategy for africa focusing on 3 regions of the au with field work in 5 target member states benin cte divoire nigeria kenya and southafricauprise assembles 5 building blocks for knowledge generation and implementation 1 roadmaps for a shared quality culture and possible integration of the informal sector in the afss 2 strengthening the food safety regulatory framework with focus on mycotoxins in both formal and informal sectors 3 early warning to prevent mycotoxin contamination and adapt to climate change 4 prevention of food losses and improving food safety by providing innovative microbiomebased solutions for mycotoxin reduction and nutritious food and 5 cocreation training and mentoring uprises cocreated solutions will be demonstrated on 5 representative fermented food product value chains based on maize millet sorghum or milk and will be implemented in 10 business cases of smes in the target au member statesuprise builds on strong synergies between all excelling consortium members combining social sciences with technological approaches and an outstanding network which has been complemented with the accelerator platform comprising ao competent food safety authorities farmers consumers and trade organizationsuprise guarantees sustainability through the creation of training hubs in each target member state an aueu microbial biobank network early warning systems a risk assessment toolkit and a food safety regulatory model
studying urban movements of an avian model species to understand the role of biodiversity for the spread of zoonoses zoonoses and urban movement bird biodiversity assessment

human population in cities is expected to increase globally by 1 billion before the end of the current decade leading to a 1218 million km2 expansion of urban areas the planning of natural environments in cities is essential to provide a broad array of ecosystem services like mitigation of extreme weather events clean air and recreational opportunities however these benefits need to be considered together with the possible costs that may arise due to increased possibilities of humanwildlife conflicts such as those caused by the spread of zoonotic diseases tickborne diseases such as lyme disease mediterranean spotted fever q fever and crimeancongo hemorrhagic fever are major health problems forecasted to become increasingly important in europe in the next future and require close monitoring birds are an effective and fast means of transport for thicks and can facilitate the spread of diseases most available researches sample ticks from birds and other wildlife to asses the presence absence of pathologies in natural habitats or use spatial modeling to forecast the distribution of diseases based on bioclimatic variables however studies that directly trace the role of birds movements in urban areas to define gradients of risks for the local population are lacking additionally it remains controversial whether higher biodiversity by strengthening ecosystem stability and creating a dilution effect decreases the risk of zoonosis spreading or whether higher biodiversity may actually enhance and propel the diffusion of pathogens the current proposal aims at testing 1 if emerging tick borne diseases are present in spanish cities of different sizes barcelona valencia toledo 2 if the movement of parus major a non migratory species of bird can be used to trace the distribution and spread of of tick born diseases within urban areas 3 if the distribution and occurrence of tick born diseases covary with the levels of local biodiversity
dissecting the brain basis of obesityinduced pubertal alterations a view to a kiss

child obesity is a worrying condition affecting 20 adolescents among its comorbidities early obesity is linked to disturbed puberty which is more evident in girls but bound to adverse health outcomes in both sexes yet how our brain decodes nutritional info to finely control puberty remains unsolved genetic data suggest obesity is largely an hypothalamic disease puberty is also hypothalamicdriven and governed by complex neuronal circuits among them kiss1 neurons have emerged as key elements in the brain control of puberty and its metabolic regulation likely in cooperation with other central signaling systems as pomcmelanocortins yet the mechanisms whereby early obesity impacts on different kiss1 neuronal populations and pubertal timing are illdefined the global aim of dopakiss is to unveil the brain basis of obesityinduced pubertal alterations in both sexes with a major focus on kiss1 neurons an integral research plan will be implemented based on i multidimensional integration of omics data including hypothalamic global and spatial metabolomics as well as transcriptomic and epigenomic profiling of kiss1 neuronal subpopulations during pubertal maturation in conditions of obesity ii analysis of the molecular mechanisms for nutrient metabolic sensing at the hypothalamus and particularly in kiss1 neurons and iii functional genomic dissection of key metabolic pathways in kiss1 neurons using creloxp crisprbased genome editing in vivo sex differences in the impact of early obesity on subsets of kiss1 neurons and puberty and when relevant parallel changes in pomc neurons will be explored putative human correlates of our experimental data will be scrutinized using public databases dopakiss will not only surface unsolved aspects of the metabolic control of puberty but will reveal also groundbreaking info on pathophysiological mechanisms and putative targets of intervention in conditions of altered puberty due to early obesity
hybrid solid electrolyte for safer rechargeable sodium batteries with higher energy density

electrification is one of major pathways to the decarbonisation of europes transport and energy sectors which will allow europe to address the ambition to become the world first climateneutral continent by 2050 rechargeable batteries will help decarbonise transport sector and enable a higher uptake of renewable energy and are therefore strategically important to europe the hysobatt project aims to develop a hybrid solid electrolyte comprising aligned nasicontype inorganic nanofiber networks embedded in sodium na conducting polymer electrolyte which can be used in rechargeable solidstate na batteries and to markedly improve batterys energy density and safety such solidstate na batteries will be a promising lowcost alternative to the current widely used lithiumion batteries libs without the need for any critical raw materials that may bring potential supply risks for upscaling the lowcost and improved safety of solidstate na batteries will also promote their wider adoption in the battery market in the future the applicant has extensive handson experience in sodiumion battery research and he will be able to extend further the breath of his research and gain a holistic view about the rd of rechargeable na batteries the host institution will arrange a number of training activities helping the applicant gain new competences and skills not only in scientific research but also in project management reporting proposal preparation ip protection and science communications the proposed research is aligned with both the sria of batt4eu and the national and the host institutions strategies on batteries both the applicant and the host institution will benefit from the twoway knowledge transfer all research and training actions will significantly enhance the applicants future career prospects helping him move towards a higher career path after the project the project results will be disseminated to different target groups
implications of digital transformation for migrant labour

accelerated by the covid19 pandemic rapid digitalisation has fundamentally transformed european working conditions while its positive consequences are well recognised digital transformation also puts a sorely needed part of the european workforce at risk of unemployment poverty and social exclusion idilab implications of digital transformation for migrant labour investigates the impacts that technological progress and subsequent structural changes have on the labour market integration of migrant workers by developing a new methodological approach idilab shall provide novel evidence on migrants exposure to the process of digitalisation and formulate evidencebased and innovative policy options for the eu and national governments to improve on the scope and adequacy of national and european policy directed at encouraging a fair digital transition for all including migrants the proposed project will contribute with new knowledge on migrants own perspectives on barriers and enablers for a sustainable integration in a fastchanging labour market i the experienced researcher dr olga gheorghiev the czech republic will work with a european centre of excellence the research centre for digitalisation of public services and citizenship cedic oslomet norway and the european trade union institute etui belgium for intersectoral knowledge transfer career development and european added value
biobased and recycled paving materials with optimised and advanced durability for road infrastructures

roads are indispensable to our daily lives promoting mobility and supporting socioeconomic interactions however the impact caused during their construction ie extraction and transport of raw materials and production cannot be disregarded moreover asphalt will be used for the next decades in road infrastructures because of its pragmatic applicability therefore it is crucial to identify ways to mitigate their environmental influence and make them more sustainable the bioroad2 project seeks to participate in the ongoing research by applying circular economy principles encouraging the reuse recycling of asphalt and biowaste and biobyproducts often limited due to regulations performance blockers and technological challenges into new paving materials to decrease the use of virgin and fossil resources it also aims to emphasise the benefits of lowenergyconsuming processes fostering the reduction of greenhouse gas emissions and related issues bioroad2 will highlight the overall benefits of all phases of pavement development including its circularity often neglected during the rd phasetherefore bioroad2 will adopt an integrated approach ensured by a threepillar ri strategy including 1 requirements definition 2 experimental studies through design and characterisation combined with 3 sustainability assessments addressing the technical environmental and socioeconomic compatibility the objectives are to i specify and document the criteria for the materials and suitable use area validation and propose a unique flexible and verifiable selfdevised method supported by literature ii produce samples verify their recyclability and identify the best mixtures and iii conduct rigorous sustainability assessments for the selected mixtures and translate the results into knowledge that can be exploited as a generalised approach for biobased and recycled paving materials with optimised and advanced durability for road infrastructures
sustainable photovoltaics integration in buildings and infrastructure for multiple applications

europes ambitious target of reducing greenhouse gas emissions by 55 by 2030 presents a significant challenge and addressing it requires innovative solutions the sphinx project aims to accelerate the adoption of photovoltaics the cheapest source of energy by developing new photovoltaic products for integrated construction that are multifunctional aesthetically pleasing and have a minimal impact on resources such as land and materialssphinx aims to demonstrate solutions for an economic and sustainable integration of five innovative pv products in five respective demonstration sites covering different construction typologies lightweight modules for installation on rooftops with weight constraints tiles for heritage buildings tiles for facades semitransparent modules for carports and noise barrierseach of these products will be piloted and monitored to demonstrate high energy production low degradation rates competitive installation costs and a low environmental impactto increase the efficiency of solar modules sphinx is leveraging a disruptive european interconnection technology known as matrix shingling this technology improves the filling of the active area of solar modules leading to a 3 increase in power output and make them less sensitive to shading this translates to up to 3 times more energy yield compared to standard modules under strong partial shading furthermore this technology drastically reduces the use of resources such as lead and copper to further enhance module performance sphinx will add new functionalities to the encapsulant including uv selective absorption and reemission for power increase selective reflection of ir light to increase bifacial boost and reduce temperature behind the panel new coatings will also be developed to provide antiglare and antifouling capabilities based on a new deposition process that can be reapplied in the field in case of damage