Dragon09/odtu_chatbot huggingface dataset:
artificial intelligence based health optimism purpose and endurance in palliative care for dementia

dementia is caused by a range of illnesses and disorders that damage the brain either directly or indirectly with the rise of the ageing population in the eu dementia is becoming a serious problem digital health interventions have the potential to improve the accessibility and effectiveness of palliative care palliative care is an area where these technologies are increasingly being evaluated for education eg online learning mobile applications or virtual reality tools symptom management care planning decisionmaking and interaction eg professionals and caregivers using phones internet and computer systems however most studies focus on a specific intervention with heterogeneous outcomes and are exposed to professional gatekeeping and biased samples consisting of patients who are mostly well and without considering cultural impacts due to improved understanding and treatment more effective and innovative health technologies improved patient safety and better ability and preparedness to manage epidemic outbreaks along with priorities related to quality of life of dementia patients and survivors treatment and dementia data monitoring should be crucial this project will focus on i better understanding of dementia focusing on their consequences including pain distress and causative links between health determinants disease and interventions in order to provide evidencebase for policymaking ii identification of holistic intervention treatment and care and assessment of health outcomes iii innovative digital tools to optimize clinical workflows and iv scientific evidence for improvedtailored policies and legal frameworks and to inform major policy initiatives at eu and global level we target exactly those aspects of value by integrating digital interventions as palliative care of patients with poor prognosis of dementia and evaluating the impact of digital health interventions using artificial intelligence
quantumenhanced nonlinear imaging

many pioneering advances in medicine and biology require observation of the microscopic world with high resolution and without damaging the specimen one of the most widespread techniques is multiphoton fluorescence microscopy which allows full 3d imaging via optical sectioning ie imaging of planes within the sample without the need for physical slicing this technique has a major limitation however the penetration depth and the signaltonoise ratio are not sufficient for imaging deep within tissue preventing functional imaging of eg neuronal or cardiac activity beyond superficial layersqunim aims to transform the field of nonlinear imaging and microscopy by exploiting the unique properties of entanglement a quantum mechanical superposition of two or more photons that behave like single particles two quantumcorrelated photons are absorbed in a nonlinear process as a single particle an event 10 billion times more probable than the absorption of two classical photons qunim will apply for the first time the innovative concepts of spatiotemporal and multimode entanglement superpoissonian fluctuations and macroscopic quantum beams to deliver a groundbreaking imaging technique it will maintain the strengths of standard nonlinear imaging eg multiphoton microscopy boasting high resolution 3d imaging and molecular specificity using fluorophoresphotoproteins while increasing its penetration depth and removing the drawbacks complex ultrashort pulsed lasers lengthy scanning procedures and phototoxicityqunim will further extend the limit of deeptissue imaging while at the same time enhancing the contrast and reducing the laser intensity mitigating tissue damage delivering a transformative impact in different fields for example in neuroscience this will allow imaging of eg subcortical brain regions fundamental for important studies into learning memory and degenerative neural conditions such as alzheimers disease
smart management of energy and costs in museums a chemical background for a control methodology for temperature and relative humidity fluctuationss

fellow paola lucero host institution palack university olomouc upolcz supervisor karel lemr department of analytical chemistry dacupol cosupervisor petr bednar dac upol host institution and supervisor secondment cafoscari university cfu it isadora antoniano host institution and supervisor nonacademic placement gallerie dellaccademia in venice gav it silvia salvini aim of the project ro1 to give to the methodology that i published in 2020 for monitoring and control of fluctuations of temperature and relative humidity in museum environment a chemical background considering materials degradation ro2 to gain knowledge into materials degradation and determine what fluctuations can be tolerated by museum objects without damage ro3 to gain knowledge on historical buildings behavior and their capacity dumping outdoor weather variations ro4 to transfer the gained knowledge by training an initial set of endusers in cultural institutions to help them managing their energy consumption innovation creation of a methodology for characterization of museum indoor environment that considers material degradation enable conservation professionals to estimate how safe is museum environment in historical buildings under climate change influence to contribute saving energy by allowing wider yet safe fluctuations of temperature and relative humidity in museums with mechanical air conditioning systems procedure and data gain knowledge on materials behavior using analytical techniques to characterize degradation in mockup samples naturally and artificially aged and combine this data with the characterization of indoor environment in museums results 2 journal articles 4 conference presentations 7 workshops 5 public events an online professional forum online data repository for temperature and relative humidity museum records partner institutions gav esk krumlov castle viking museum hist museum of oslo nat heritage institute cz
black narratives of transcultural appropriation constructing afropean worlds questioning european foundations

how is europe imagined by african african european and african diasporic writers the research project argues that there is a temporarily and spatially expansive only partially known black literary tradition engaging with europe in subjective and aesthetically innovative ways this tradition has not yet been studied from a perspective anchored in literary studies the project proposes a new literature specific and comparative approach by employing transcultural appropriation as a heuristic lens this will allow focusing on the following aspects1 on literary strategies of transcultural appropriation ie on ways of imaginatively building afropean worlds shuffling hierarchies reversing neocolonialist discourse rewriting modernity and employing a rhetoric of property 2 on literary references to neocolonial logics of property heritage and belonging ie on ways of revealing and questioning the european foundations that forced black people into the position of being appropriated or excluded from claims of ownership since colonialism and slaverythe goal is to develop a new perspective on europerelated black literature that challenges the reactive dependency and balances the anglo or francocentric orientation associated with the framework of writing back this will be achieved by studying texts written in minor and midsize european languages depicting middle eastern and provincial parts of europe revealing gray areas beyond dominator vs dominated disclosing forgotten colonial histories and addressing europe as a unitythe scholarly impact is threefold 1 the focus on a black multilingual heterogeneous europe will revise research on europe in comparative literature 2 the literature specific methodology will bring a missing disciplinary perspective to african european studies 3 the utilization of an explicitly transcultural theoretically refined concept of appropriation will challenge ongoing scholarly and cultural debates
solidstate ionics synaptic transistors for neuromorphic computing

neuromorphic computing will revolutionize artificial intelligence for applications such as autonomous driving smart diagnosis or naturallanguage understanding by emulating the operation of efficient biological neural networks the main challenge in this field is the substitution of conventional transistors for synaptic transistors able to learn in ways similar to a neural synapse ie the development of multistate nonvolatile transistors however currently existing synaptic transistors have been developed using electrolytes that are by nature unstable and difficult to integrate such as ionic liquids or proton conducting polymers transionics will deliver highly stable nonvolatile siliconcompatible and scalable solid state synaptic transistors by exploiting the firstever room temperature oxideionic electrolyte developed in the erc cog grant ultrasofc held by the pi transionics transistors are able to modulate its channel properties with external stimulus like real neurons by reducingoxidizing a mixed ionicelectronic conductor unveiled at ultrasofc additionally transionics is compatible with mainstream microelectronics fabrication technology which makes it ideal for developing high density brainlike computer chipsthe goals of the transionics project are i to evaluate the technical feasibility for the fabrication of unique allsolidoxide synaptic transistors with lateral architecture ii to assess the silicon compatibility and scalability of the transionics transistors iii to define an ipr strategy for technology transfer iv to build a value proposition for a startup company and to identify customer segments with industrial partners to achieve these goals the pi has joined around the project team that combines applied research technology transfer and market uptake expertise
impact and viability of a novel mass pcr testing method as a pandemicfighting strategy

the covid19 pandemic has not only affected our health but also our lifestyles and our economies given its high nonsymptomatic transmissibility to stop a pandemiccausing pathogen like sarscov2 early on its tracks without needing to resort to economydamaging measures would have required a mass testing strategy very early on according to some estimates up to 10 of a nations population should have been tested on a daily basis to achieve this given the exponential growth tendency of pandemiccausing respiratory viruses as soon as such pathogen is identified a largescale testing campaign should immediate be deployed a strategy adopted successfully in very densely populated areas of china and given the long periods required to develop other pandemicfighting strategies ie such as vaccines and quick diagnostic tests pcrbased mass testing could be the ideal front line of defense since it can be developed in only a few weeks after decoding the genetic map of the pathogen but although pcr testing capacity has greatly been increased worldwide regularly testing large fractions of the population would still remain prohibitively costly with current technologythe pcr4all consortium combining expertise in diagnostics highthroughputscreening virology disease modelling econometrics and digital health platforms will aim to demonstrate the technical feasibility of carrying out populationwide pcr testing by demonstrating a capacity of 105 tests in a single day and platform in an extremely costeffective manner at least 2 orders of magnitude cheaper than currently we will furthermore evaluate the effectiveness of utilizing this strategy as the main pandemicfighting measure by assessing its ability to minimize or even prevent the need to implement other costly and partially ineffective measures ie lockdowns and vaccination campaigns
sustainabilityadvanced and innovative networking with 6g

sustain6g will develop a holistic sustainability framework in the context of 6g addressing all three sustainability areas environmental societal economic and factors impacting sustainable 6g technology and 6g technology for improving verticals sustainability the framework will be applied to key vertical sectors in an endtoend manner considering the full lifecycle of assets sustain6g will identify the crosspoints between what sustainability needs are which challenges 6g and verticals need to consider what 6g should do to address these challenges and how society and economy benefit from responsible innovation to achieve this the project will provide a driving force for multiple activities and a hub to integrate research and innovation from previous and ongoing projects develop innovative concepts and solutions and address gaps and tradeoffs in technology processes and methodologies the concepts and solutions will be validated and evaluated by proofofconcepts on their sustainability impact and performance the insights from these pocs and the proven processes and methodologies will be consolidated into guidelines best practices and roadmaps to drive the full integration of sustainability aspects into future communication and vertical systems in close collaboration with stakeholders and other sns projects and for use across the eu and beyond the outputs and impact of sustain6g will provide the foundation for industrywide standardisation that will enhance existing ecosystems help to shape a sustainable future that develops and thrives within planetary boundaries and strives to protect and restore the environment while respecting eu values and rules recognising the complexity and multifaceted characteristics of sustainability sustain6g will achieve these objectives through its multidisciplinary consortium composed of 6g and vertical technology social science and economic experts and with relevant external stakeholders
from subatomic to cosmic scales simulating modelling analysing binary neutron star mergers

what is the nature of matter at supranuclear densities what is the expansion rate of our universe these open questions of nuclear physics and cosmology can be answered with multimessenger observation of merging binary neutron stars the window to study these fascinating events has only recently been opened with the upgrades of gravitationalwave observatories and by combining gravitationalwave information with that of powerful telescopes in the electromagnetic spectrum from infrared to optical to gammarays in the near future we expect numerous multimessenger observations of compact binary systems we are currently at a crossroads in which the development of accurate and robust theoretical models is crucial to keeping up with the development of experimental instrumentation without noticeable upgrades of our models future analyses will be biased through modelling uncertaintiesthe proposed research project will focus on the development of theoretical models to interpret the binary neutron star coalescence and will pave the way for a thorough understanding of the merger process novel methods and algorithms that we will implement in our numericalrelativity code will allow us to study previously inaccessible regions of the binary neutron star parameter space with unprecedented accuracy this accuracy in the determination of the gravitationalwave and electromagnetic emission from binary neutron star mergers is essential for connecting our theoretical computations with observational data we will push for a publicly available framework for the simultaneous analysis of gravitationalwave and electromagnetic signals from binary neutron star mergers incorporating also nuclearphysics calculations nuclearphysics experiments and other astrophysical observations of isolated neutron stars this framework will enable us to use upcoming detections to determine the neutron star radius and the hubble constant
bridging gaps in mental health support a comprehensive european strategy

europe should be prepared for a mental health crisis that will last for decades impacting on longterm health outcomes and economic productivity of our current generation of youth unfortunately the present mental healthcare system fails to match their needs 50 of european youth have unmet mental health needs and only 30 receive appropriate care therefore youthreach aims to tackle the expanding european youth mental health crisis by bridging gaps in mental health support and provide a comprehensive european strategy youthreach will evaluate costeffectiveness of 3 existing and accessible innovative interventions for prevention and early intervention of mental illhealth in youth that have been developed and tested in cocreation with youth 1 walkin youth mental health support centres operational in 6 european countries and australia 2 a guided selfhelp mhealth intervention operational in 1 european country 3 clinical and peermoderated digital treatment platforms operational in 2 european countries and australia in addition feasibility and acceptability at new sites across europe will be tested best practice recommendations will be developed and built with existing and new data into an integrated european youth mental health framework finally awareness and accessibility of these interventions among policymakers including hta bodies sociologists ethicists healthcare professionals citizens and the target group will be increased youthreach activities will benefit from engagement of and cocreation with young people and their support network for the whole duration of the project and a lasting privacy protected accessible fair research data infrastructure and an open science framework in the field of youth mental health and health services research youthreach will impact by transforming the present traditional mental healthcare system tackling the current crisis and offer perspective health and productivity to the next generation
advancing the market uptake of diamond defects quantum sensors

amadeus is an industryoriented consortium that will prepare the market uptake of quantum sensors exploiting nv centres in ultrapure diamond one of the most promising and marketready technology of quantum sensing amadeus capitalises on the ongoing asteriqs project that develops this technology to trl 45 in the rampup phase of the quantum flagship four advanced applications will be pursued up to trl 67 to answer societal and economical needs where no solution exists yetprovide a realtime cartography of the rf signal frequencies in 5g communication cellular networks and further on future 6g enabling selfoptimizing networks in dense area thus increasing the number of communications and lowering the energy consumptionprovide a tool to the semiconductor industry to analyse the defects in microelectronics circuits at room temperature and in standard environment in order to increase the throughput and lower the cost productionenable monitoring the muscle and brain activity as novel medical diagnostic tool or as brainmachine interface in the future use monitoring of the magnetic field as a multipurpose tool in harsh environment for space applications or for monitoring of the transient currents in electric car batteries the consortium involves large companies rtos smes and academic partners it addresses the whole value chain from the diamond material to the system working in operational environment along which the workplan is organised the partners will produce the material and the components that will be assembled in operational systems and will disseminate the results towards large audiences including endusers key actions will be taken to support the transfer to market in collaboration with major european metrology institutes amadeus will contribute to the standardisation and certification of quantum technology consequently amadeus will reinforce the european quantum industry for the benefit of europes economy and citizens
development of a natural therapeutic treatment for latestage lung cancer patients

celtic biotech ireland has developed cb24crotoxin a naturally derived receptor binding protein delivered as monotherapy at home using infusion pumps is hailed as a life changing treatment of nonsmall cell lung cancer nsclc delivered intravenously cb24 induces predictable and consistent apoptosis cell death and autophagy degradation in human lung carcinoma cells cb24 outclass the competitive nsclc treatment solutions surgery chemotherapy and radiotherapy through its efficacy safety minimal sideeffects easy to use home based treatment and suitability for all patients including those at stage 3 4celtic have already proven the efficacy of cb24 through preclinical and fih clinical trialsthrough the proposed 24months eic project the company aims to undertake phase i part 3 clinical trials involving 24 patients with the ultimate goal of garnering the regulatory approvals ema fda to market the drug as a verified cancer therapeutic
metal exsolved catalysts for the co2 valorisation to methanol design synthesis and characterisation of nextgeneration catalysts unravelling their structureactivity relationship

the european union goal of a 8095 decrease of greenhouse gas emissions by 2050 requires among other strategies new functional materials and sustainable approaches for clean energy generation and pollutant abatement the chemical valorisation of co2 is a highly promising green solution involving the recycling and reuse of co2 effluents as carbon source for fuels and chemicals such as methanol the low co2 conversion triggered by catalytic nanoparticles nps deactivation by sintering and limited selectivity however limits its industrial growth the first aim of this proposal is to design nextgeneration stable and selective catalysts for the co2 hydrogenation to methanol that can rival stateoftheart materials through the ambitious achievement of 10 methanol yield this will be done by np exsolution a novel route to achieve stable anchored nps which has barely been explored for this application despite the superior catalytic properties unique to exsolved systems to then unravel the lack of fundamental understanding in the catalytic mechanisms of exsolved systems we will characterise the correlation of their structure with their reactivity and selectivity via a unique in situoperando approach second aim the role of active sites such as exsolved nps and structural defects will be elucidated by in situoperando infrared ftir and raman studies we will monitor the composition and strain evolution of the materials surfaces during catalytic processing by stateoftheart in situ photoelectron spectroscopy xps and transmission electron microscopy tem the unique expertise of the host supervisor in co2 hydrogenation catalysts testing and characterisation by in situoperando ftir and raman and of the secondment group in xps studies of catalysts onstream coupled with my experience in exsolved systems design and in situ tem characterisation will advance the fields of exsolution and co2 valorisation catalysis allowing me to gain a unique skillset