Dragon09/odtu_chatbot huggingface dataset:
clinical validation of an aibased approach to improve the shared decisionmaking process and outcomes in breast cancer patients proposed for locoregional treatment

breast cancer is the most commonly diagnosed cancer with an estimated 23 million new cases per year globally approximately 90 of these patients will undergo breast surgery withwithout radiation locoregional treatment different surgical techniques can be offered to the patient each leading to completely different aesthetic outcomes moreover for different patients undergoing the same surgery the aesthetic outcome could be completely different based on individual patients factors eg age body habitus in the cinderella project we will be using the brelo ai system an artificial intelligencebased tool for classification of aesthetic outcomes and matching data and photographs integrated in cankado a cloudbased healthcare platform to create an easytouse application that can be used on any electronic device to simulate visually to the patient the aesthetic outcome of a certain surgery the cinderella approach is unique as it uses a clinical database and performs biometric matching to create images that simulate to the patient the outcome of surgery in the cinderella trial running during the project we plan to compare if the application helped to fulfil the expectation and lead to a better quality of life by feeding new clinical and photographic information to the cinderella approach after surgery the artificial intelligence platform will be able to improve for the next cases this trial will be practicechanging in the field of patient education and shared decision making cinderella platform will help to overcome any miscommunication and potential boundaries in patients or physicians understanding of the potential outcomes of locoregional treatment of breast cancer we believe that the cinderella approach will be used in the future to other locoregional treatments that might change patients aesthetic appearance thus cinderella approach will be the forerunner for new innovative tools for communicating with our patients
field quantum gravity sensors

gravimetry aims at unveiling the density structure of the undergrounds by measuring subtle changes of the local gravity acceleration the firstgeneration of quantum gravity sensors qgs has received a strong interest from many customers and the market is still growing but the commercial potential and the positiveimpact of the technology are not yet fully exploited because of several limitations such as transportability robustness userfriendless or high operation costs to overcome the barriers that limit the operational utilization of field gravimetry and develop the solutions that will allow us to fully address the exploitable market we propose to conduct in fiqugs the development of several innovations either at the technological level with improved qgs built upon a reliable and efficient supply chain or in terms of operational methodologythe development of a next generation qgs product line and the services associated for the conduction of field surveys data acquisition and data inversion will allow to considerably develop our capability to address the market of advanced geophysics the unique industrial and technological capabilities that will result from fiqugs will positively contribute to several important societal objectives especially the european green deal the new field qgs will allow for a reduction of the environmental impact associated to mining activities thanks to a reduction of drilling operations and civil engineering where it will contribute to more efficient and resilient constructions they will contribute to an improved utilization of geothermal energies through the development of noninvasive monitoring capabilities of the energy reservoir they will be involved in co2 storage operations and will contribute to the fight against global warming thanks to these advanced monitoring capabilitiesfiqugs will also have an impact in quantum technologies markets such as highperformance navigation or advanced photonics
a pioneer clinical trial management system to automatically collect review and analyse prospective clinical trial data to prompt faster development of novel therapies

yonalink yl is an israeli company established in 2018 with the mission to disrupt the 46b clinical research market by connecting the world of prospective clinical trial data to this end yl is developing the yl system a platform to migrate clinical research data saved in the patient health records from medical centres to research databases in an automated secure validated trusted and errorfree way the company has secured over 18m in the development of the yl system reaching trl 7 with pilot trials implementing it at soroka mc clalit health insurance leading hospital and in sheba mc the trials have confirmed the accuracy in migrating patients deidentified data from the ehr to the trial db eic support will allow yl to finish optimization and validate the yl system in a multicentremultinational pilot demonstrating the advantage of automatic data transfer from ehr to the prospective trial database to all the clinical trial stakeholders in the eu
graphene transistors for highdensity braincomputer interfaces

we have developed a novel type of graphenebased transistors capable of delivering highresolution brain mapping implementing multiplexing strategies and monitoring activity across a wide range of frequencies including low frequencies we circumvented the bottlenecks faced by other approaches thanks to the unique properties of graphene graphene is an outstanding conductor and provides the perfect platform for multiplexing thus our system requires much fewer wires than current alternatives further graphene is just one atom thick flexible and can be integrated into ultrasoft flexible substrates providing excellent contact with brain tissue our graphene transistor technology has been developed as part of the fetgraphene flagship and fetproactive braincom projects we have assessed the technology in rodents and demonstrated that our devices allow monitoring brain activity with very high spatial resolution and over a wide bandwidth frequency range this project will pave the way for the clinical translation of brainmapping neural interfaces based on graphenetransistor arrays for braincomputer interfaces
powerful lawful interception investigation and intelligence

poliiice vision is to advance european leas to a novel lawfulinterception li investigation and intelligence era in which they will be able to effectively prevent detect and investigate crime and terrorism amid the new age of communication 5gbeyond endtoend encrypted communication and quantum based encryption these new age technologies turn legacy li solutions to totally ineffective and therefore put significant risk on europes fight against crime and terrorism poliiice will offer research validate and demonstrate array of innovative li measures at cloud network level as well as at edge device level that together will enable leas to efficiently overcome the new age challenges and enable high throughput of its li in addition poliiice will research and model quddaas quantum unlock detection and decryption as a service as an envisaged central service potentially outsourced at pan eu level which will harness quantum computing for decryption of lawfully intercepted encrypted communication which is vulnerable to quantums shor algorithm for brute force detection of targetusers credentialstokens needed to access encrypted cloudnative apps and for quantum unlock of lawfully seized edge devices quddaas may also detect and classify li communications that are resistant to quantum decryption power and therefore cant be decrypted poliiice also aims to improve the information exchange and cooperation among european leas by proposing and implementing a mechanism and procedure for exchanging pseudoanonymized suspect identifiers poliiice is designed for ensuring the costeffectiveness security and integrity of the new age li and will provide the legal and ethical framework for each of its measures while strictly complying with privacy preserving and ethics rules of operation poliiice will contribute to the li standardization and will recommend eu regulation changes for effective adaptation of poliiice vision and innovative li measures
fellowship residencies offering science news professionals tools and training for independent and ethical reporting on science

the overall objective of frontiers is to establish a program supporting science journalists residencies in european research institutions through a financial support to third parties mechanism the program aims to and contribute to tackling the challenges of science journalism specifically in the highly challenging area of frontier research as well as increasing the opportunities of interaction between research institutions and science journalists the residency program will be established based on the principles of journalistic independence and the need for coverage of frontier as oppose to other types of research to ensure a smooth and successful operation we will develop a coordination and support office cso that will oversee the development and implementation of the residency program and the ongoing management and monitoring the cso will also provide support and complementary services including a general and frontier science helpdesk for journalists researchers and staff from hosting research institutions matchmaking services to help journalists find hosting institutions our project activities will be supervised and accompanied by a strong advisory board consist of actors from the areas of science and science journalism ensuring the independency and credibility of the program resident journalists and researchers and research staff participating in the program will also benefit from training activities and content contributing to the creation of meaningful journalistsresearcher collaboration and the generation of highquality and credible science journalism products during the project we will also benchmark the frontiers residency program to other available programs offering fellowships to science journalists and implement best practices to ensure the quality of the program finally we will explore paths towards sustainability the residencies through additional funding channels
quantumsafeinternet

qsi aims at training a worldclass cohort of doctoral candidates dcs capable of taking the next essential steps in the highly demanding area of cybersecurity we aim to build strong lasting links between strategically selected industry and academic partners in different disciplines via the development of novel technologies for practical applications in data security in parallel we will also combine via a collaborative longterm interdisciplinary approach expertise in all relevant communities to address key fundamental problems in secure communications in the quantum era and the important applications therein the planned training network will provide research and training opportunities to a new generation of dcs who in the longrun shall address the grand challenge of providing quantumsafe internet ie a communication infrastructure that is secure against not only classical attacks but also those enabled by quantum technologies todays internet security heavily relies on computational complexity assumptions and as such is seriously threatened by advancements in quantum computing technologies indeed we have recently witnessed a wave of key developments in this direction by a number of it giants eg google ibm microsoft and intel this particularly jeopardizes applications that require longterm security the number of such applications is continuously growing as more and more of our private information is stored and communicated in a digital way eg electronic health records which are now required by european legislation to remain secure for a long time this requires us to urgently develop and implement new solutions as we plan to do in this doctoral network dn
the mutual effect of levels of trust and regulation over time analyzing energy regulation in the european union

trust and regulation are key aspects that allow the advancement of the society in setting regulations to govern the behavior of citizens firms states and policymakers adopt regulatory design choices that are partly grounded in trust between them and key actors in the field at hand however we do not know a lot when it comes to iterative processes through which trust and regulation affect each other over time through a combination of quantitative and qualitative methods truregen aims to study the bidirectional relation between levels of trust and regulation focusing on the case of eu energy regulation during 20082022 the project 1 maps the nature of eu energy regulation along two key dimensions specificitybroadness stabilityrevisability 2 assesses statistically significant relations between such a nature and current and past levels of trustdistrust among key eu and national actors policymakers regulators regulatees consumers citizens and 3 traces causal mechanisms underpinning these statistically significant relations expertise and facilities offered by the host ku prof latusek together with my existing experience and talent mutually reinforce my development as independent researcher during the fellowship in addition advanced training eg statistics grant writing science communication twoway knowledge transfer allow me to realize my longterm career goals after the fellowship a customized dissemination and communication plan will make the project and its results known well beyond the academic community while also seeking active engagement with a wider audience eg workshops class experiments altogether truregen at once bridges a major scientific gap enhances my future career prospects and makes a timely contribution to pressing societal debates
the formation and evolution of the primordial planetary felsic crust

a turning point for the whole planetary evolution climate and habitability was the onset of felsic ie enriched in si and al crust formation 45 40 gyr ago to date this onset can be traced using natural zircon mineral zrsio4bearing rocks as well as laboratory experiment and modelling my project is based on cuttingedge experiments and modelling as well as field data acquisition on natural rock samples to construct a first comprehensive fundamental model of the primordial felsic crust formation and evolution on earth and very likely mars and venus my recently established laboratory experimental protocols and modelling approaches open a new window to understanding of how the zirconbearing felsic magmas rocks and crust can be produced from the ultramafic rocks mg ferich and si alpoor that dominated early planets compositionplanetafelsic has four research objectives i to identify and explore the rockforming processes that controlled the formation and evolution of the primordial felsic crusts on earth mars and venus ii reevaluate what physicalchemical conditions are reflected by the trace element and isotope signatures of zircon formed and evolved in the presence of magmas and fluids iii to constrain the initial steps of planetary geodynamics ie rockforming reactions transformations and movements and how they are recorded in the trace element and isotope signatures in mantlederived rocks iv to construct a geochemical model of the habitable conditions during the early evolution of the rocky planetary surfacewith planetafelsic grant i will build a team dedicated to addressing these challenging goals in a comprehensive way ambitious but feasible and timely planetafelsic will significantly advance our understanding of how the habitable conditions could be formed on the planetary surface this will pave the route for future missions to mars and venus and exoplanet exploration
interplay between chirality spin textures and superconductivity at manufactured interfaces

memories that operate at cryogenic temperatures are urgently needed to realize advanced quantum and superconducting computing systems that will enable more efficient and scalable computing systems beyond todays reach supermint proposes to combine the latest advances in superconductivity and spintronics to build a novel supertrack cryogenic memory that is high performance nonvolatile and that needs very low energy for its operation a major objective will be to demonstrate the generation and use of triplet supercurrents that are dissipationless but which carry spinangular momentum to move chiral domain walls in magnetic racetracks a second major objective will be to explore the origin and utilize our recent discovery of a nonreciprocal josephson diode effect to build a novel device to detect magnetic fields and thereby read magnetic domain walls for supertrack these objectives will be met by exploring and designing manufactured interfaces or mints that combine superconducting and magnetic ultrathin layers using an advanced complex of thin film deposition systems that i have constructed over the past 5 years to achieve these objectives fundamental breakthroughs are needed in the preparation of mints with highquality interfaces a wideranging exploration of mints formed from superconducting layers with chiral antiferromagnets homochiral layers of chiral compounds especially from the b20 family of materials and geometrical chiral structures will be undertaken in addition the concept of obstructed atomic insulators that we have recently developed will be used to identify novel interfaces of insulating materials that are metallic and thereby to explore the possibility of making these superconducting by pairing electrons via chiral antiferromagnetic fluctuations in adjacent layers
in silico clinicallyviable assistive tools for prediction and rehabilitation of knee osteoarthritis

knee osteoarthritis koa is a leading cause of disability worldwide with 14 prevalence in europeans aged over 40 koa prevalence continues to rise thus far with no cure or proven prevention protocols nonetheless an aberrant knee mechanobiological environment is known to accelerate koa development tailored rehabilitation aiming to favorably alter knee biomechanics and restore the joint has shown great potential to postpone or decelerate koa progression but current rehabilitation protocols are based on indirect measures of knee biomechanics often leading to suboptimal outcomes computational models have offered great potential for simulating knee mechanical response in functional activities though none are developed in a holistic and individualized context more importantly they lack the prediction capability of tissue degenerationregeneration to loading and the potential for clinical use ie are not automated and fast and cannot use outoflab motion data in this project i will develop and validate highly personalized in silico tools to quantify knee cartilage mechanobiological degenerativeregenerative response geared towards outoflab and clinical use for predicting koa progression in different functional activities allowing personalized rehabilitation the multiphysics computational models assisted with artificial intelligence ai will be validated at different spatial scales using in vitro tissue and cell level experiments and in vivo joint loading and quantitative medical images this multidisciplinary project bridges together complementary skill sets of dr esrafilian profs korhonens and delps teams with their expertise in biomechanics computational modeling biochemistry biology and ai the beyond stateoftheart models of this research can make a profound impact on earlystage koa prediction and treatment planning potentially increasing the quality of life in koa individuals and reducing the need for surgical interventions
developing an abductive coding analysis toolkit

in qualitative data analysis oriented towards theorybuilding many data analysts anchor their methodological approach explicitly or not in grounded theory however as research in teams develops handling larger amounts of qualitative data enabled by technological developments grounded theorys principles are increasingly at odds with current practices and analysts of qualitative data are left relying on coding procedures that do not match their realities following a burgeoning literature and building on the ercfunded qualidem project we argue that shifting to an abductive approach of coding that combines deduction and induction at different stages of data analysis provides an epistemology to qualitative research that aims at theorybuilding this poc aims to develop abduction as a method of qualitative data analysis by providing a toolkit for abductive coding the abductive coding analysis toolkit acatoolkit the acatoolkit includes three main components 1 a practical guide 2 an educational program for training 3 an overview of the potentials and limits of existing qda software for abductive coding the toolkit thereby targets several audiences academics instructors data analysts and software developers our pathway from research to innovation consists of three steps 1 mapping the existing practices and tools of abductive coding in different disciplines through a systematic literature review whose results will be presented in a technical report 2 developing our abductive coding analysis toolkit through research collaborations and consultancy agreements with stakeholders educators software developers and data analysts synthesized during two cocreation workshops 3 testing the acatoolkit with different potential endusers during five in situ tests with researchers students educators software developers and data analysts the toolkit aims to be free attractive widely applicable and with a wide disciplinary range
go it

europes it hardware development is constantly challenged by outrageously expensive development tools legal constraints like ndas or patents lockin threats dependency from external vendors or supply chains and foreign political events europes digital infrastructure from consumer to critical appliances is heavily relying on foreign closedsource chips which are literally blackboxes which may and have been proven to contain malicious features this situation makes the hardware development expensive and inefficient and undermines the very principle of sovereignty resilience and reusability opensource silicon chips which are open in their entirety ie down to the physical layout carry the potential of catapulting europe into a renaissance of digital technology several challenges are on the way many of which will require the participation of the stakeholders from the fertile ground made of nerdy hobbyists and makers who are the early protagonists of the scene all the way up to large enterprises as well as the participation of policymakers and regulatory bodies the road ahead is steep but rich of rewards therefore we loudly say go it