Dragon09/odtu_chatbot huggingface dataset:
multifaceted assessment and optimization of welded structural green steel plates for use in european sustainable infrastructure

the main objective of the weldgreenplate proposal is to define the conditions for safe use of green structural steels if possible without the use of critical strategic elements for european infrastructures made of medium strength s355 to ultrahigh strength s960 steels to achieve this goal the most critical locations in these structures will be investigated the welded joints and in particular the haz future green steels will be manufactured using an increased amount of scrap likely of lower quality and containing higher concentrations of residual elements cu ni cr mo sn as sb pb zn bi and co this will modify the chemical composition of the steel grades and thus the response of the material to thermal cycles such as imposed by welding the properties of welded joints will therefore be changed making it necessary to assess these changes and remedy them if required the proposal will investigate modified alloying concepts for the safe application of clean steel in downstream processing and fabrication it is planned to investigate the application of multiple welding repairs to allow reuse of fabricated components and give the opportunity to have steel solutions with improved co2 emissions through reuse of fabricated componentsthe improved or nondegraded weldability will allow to develop new clean steel grades with improved inuse properties particularly strength and toughness in the welded conditions through application of stateoftheart techniques machine learning thermodynamic simulations fem of microstructural behaviour supported by advanced analytical techniques the latest items are innovative tools that will be available to future clean steel grades development it is in the scope of the project to find the requirements for highperformance structure steels characterized by increased tolerance to contaminants in the scrap in particular cu
semiclassical spin dynamics in condensed phase

quantum mechanical spin dynamic calculations for nmr purposes rapidly becomes very complicated when the studied spin systems increase in size in this project we aim to study methods in which semiclassical molecular dynamics are explored to tackle this problem methods for semiclassical approximations have since long times been established within the fields of radical chemistry and optical spectroscopy research but are little explored within the field of nmr we intend to explore methods where in addition to a smaller completely quantum mechanically described spin systems are investigated the complete large nuclear surrounding is included in a classical manner more specifically we will add hamiltonian terms of the caldeiraleggett type and eventually simulate the anharmonic environment with ab initio molecular dynamics or empirical force fields the benefit of the proposed strategy is that matrix size increases linearly with the number of nuclei included instead of exponentially if the environment can be described classically this will be done by a step by step project plan in which during the earlier work packages investigations of spin systems without the environment included is done then once we have established suitable quantum dynamics methods we will proceed to include the environment if this succeeds and we manage to correctly calculate spin dynamics with the impact of the environment in terms of relaxation taken into account we will continue to the later work packages and try to use this to aid nmr pulse design if this is successful this project will open doors to more efficient nmr simulations and provide quantum physical insights to nmr dynamics
unlocking lidar technology for european oems for a future of smart and safe traffic and mobility

xenomatix is radically innovating the standard operating principle of lidar by introducing a lightbased 3d measurement system and is the first to design the by market defined holy grail being a true solid state lidar xenomatixs unique all semiconductorbased design is first to meet cost size and robustness requirements without compromising measurement performance xenolidar xenomatix highresolution true solidstate lidar generates 8d environmental measurement data 2d 3d intensity images time and confidence levels guaranteeing superior detection reliability with zero moving parts xenolidar is a complete systemonchip as demanded by automotive oems abandoning traditional light projection schemes and radically turning around how light is projected into the environment xenomatix reveals the 1st true solidstate lidar with 100 proven silicon components to supply the b automotive lidar market
occurrence regulation and function of bacterial mrna editing under diverse environments

bacteria are haploid having a single copy of each gene we suggest a paradigm shift in bacterial genetics bacteria can have two rna versions of the same gene encoding protein isoforms at the singlebacterium and population level these protein isoforms can have altered activity which could be advantageous under different conditionsadenosinetoinosine atoi mrna editing can affect the sequence and the function of translated proteins because the ribosome identifies inosine as guanosine we discovered that atoi mrna editing occurs in bacteria escherichia coli identified the mediating enzyme and showed that it could affect protein function moreover we discovered that environmental cues experienced during growth in culture affect bacterial mrna editing however the prevalence and regulation of atoi mrna editing across bacteria and the importance of editing for protein function and bacterial physiology in different environments are still unknownhere we will test the hypothesis that mrna editing is widespread in bacteria producing two rna alleles pseudoheterozygosity subsequently these rna alleles may coexist in the same bacterial cell or population of cells thus mrna editing may enable the translation of protein isoforms making bacteria better adapted to changing environments we suggest 1 identifying mrna editing events across environmental conditions in hundreds of species 2 uncovering the regulatory genetic factors governing bacterial mrna editing occurrence and 3 determining the effect of mrna editing on the proteome and its functional role in bacteriaour work could shed light on a new mechanism bacteria employ to grow and survive in different environments furthermore bacterial mrna editinginvisible to dna sequencingmay account for unsolved problems or phenomena that current genetic and proteomic data cannot explain affecting bacterial biology and human health
diagnostic and antibiotic stewardship for urinary tract infections using fitforpurpose diagnostic tools

urinary tract infections utis and antimicrobial resistance amr pose significant global health threats characterised by high incidence and mortality however in subsaharan africa ssa there is often a lack of accessible diagnostics to guide proper treatment and therapy monitoring our objectives are as follows 1 develop and validate a twotier diagnostic toolbox a implement a lateral flow test lft for detecting urinary biomarkers at primary care for triage b deploy a compact portable pointofcare poc instrument for secondary care hospitals clinics integrating pathogen detection via isothermal nucleic acid amplification and hostresponse biomarker quantification for evidencebased therapy and antibiotic prescription c introduce novel selfsampling cards for transport without the need for a cold chain d establish a digital health platform for clinical decision support 2 evaluate the toolboxs field deployability acceptance usability and integration into clinical practice 3 maximise the adoption implementation and accessibility of the proposed diagnostic toolbox 4 prepare for postproject regulatory approval and market launch 5 enhance capacity building and surveillance structures through local manufacturing transfer and improvement of the supply chain and logistics we will recruit diverse patient groups including underrepresented segments of society from various african settings to ensure the broad applicability sustainability and customisability of our solutions this project is expected to have a significant impact improving the quality of utiamr diagnostics reducing unnecessary antibiotic use preventing resistance strengthening health systems and their response to epidemics and increasing accessibility and quality of diagnostics through interdisciplinary and robust industrial collaboration
the contribution of thalamocortical projections to high cognitive functions speech processing working memory and attention in sighted and unsighted populations

the proposed project aims to investigate the contribution of thalamocortical projections to high cognitive functions such as speechprocessing working memory and attention in sighted and unsighted populations in the last decades advances made in magneticresonance imaging mri have shed light on the cortical regions subserving these processes however less research has investigatedthe role of thalamocortical pathways in these high cognitive functions this could be due to the lack of detailed probabilistic atlases ofthe human thalamus or the small size of the thalamic nuclei as compared to regular voxel sizes therefore the recent creation of thefirst probabilistic atlas of the human thalamus developed by the host group opens the door to investigate to what extentthalamocortical connections relate to speech processing working memory and attentional abilities we will further investigatewhether the involvement of thalamocortical projections in the abovementioned functions differ between sighted and unsightedindividuals since research conducted in blind population has reported enhanced auditory processing at the thalamic level alteredthalamocortical connectivity and superior skills in the previous cognitive functions to address these scientific questions we will use amultimodal mri approach that combines functional and structural mri indexes with behavioral measures using regression modelswe will assess the degree to which thalamocortical connections help to further explain speech processing working memory andattentional abilities as opposed to just considering cortical indexes as it was done in the past the results of the present researchproject may have important implications as they could open a new avenue at the theoretical level updating preexisting models oncognitive neuroscience and creating new ones and regarding their application improving the diagnosis and treatment in cases ofaphasia dementia or attentional deficits
islands as natural laboratories of global warming discovering insects ability to survive thermal extremes

global warming will increase the frequency of extreme heat events exemplified by this years european heatwave these thermal extremes pose challenges to insects who play an indispensable role in terrestrial ecosystems and whose body temperatures rise with habitat temperatures given the alarming trend of global insect declines it is essential to understand their adaptability in the face of rising temperatures ignite aims to answer one of the most urgent questions in ecology todaywill insects be able to survive the upcoming heat stressto answer this question we will test insects resilience to thermal extremes using an interdisciplinary approach that integrates insect physiological and behavioral responses with relevant micro and macroclimates using stateoftheart 3d thermal imaging of the habitat we will determine how microclimatic heterogeneity combined with insect behavioral thermoregulation governs insect survival to extreme heat while such microclimatic insights are pivotal predicting longterm changes requires a macroclimatic perspective thus we will develop a highresolution climatic model of surface temperatures to forecast heatwave frequency and intensity on mediterranean islands we will test insects thermal plasticity potential with novel reciprocal transplant experiments in both the field and laboratory we will use ants as model insects due to their global distribution and ecological importance under temperature extremes projected by the macroclimatic model we will determine ant thermal plasticity and its ramifications on ecosystem functions such as seed dispersal plant productivity and biodiversityignite integrates findings from climatology behavioral ecology and ecophysiology to understand insect resilience to temperature increases and cascading effects on ecosystems by doing so it will pioneer global change biology research in the mediterranean region using islands as natural laboratories to study global warming
ensuring european ecs value chain sovereignty through shaping the future of ecs for automotive applications

shapefuture will drive innovation in fundamental electronic components and systems ecs that are essential for robust powerful failoperational and integrated perception cognition aienabled decision making resilient automation and computing as well as communications for highly automated vehiclesits overarching vision is to bring ecs innovation at the heart of europes mobility transformation thereby elevating sovereignty by perfecting programmable ecs solutions for intelligent safe connected and highly automated vehiclesthe project will result in the following main tangible outcomessafety security and reliability of invehicle systems to levels appropriate for massmarket deploymentavailability and supply of leadingedge ecs for the european automotive supply chain and for oems to be at the forefront of technology developments in the 2030s increased accuracy and robustness of ecs for perception with smaller form factors and lower power consumptionecs attributed with cognition features and improved humanmachine interface hmiecs with cognitive processing and decisionmaking capabilitiesecs for resilient automation and communicationsincreased technology acceptance that will also lead to business sovereignty safeguard15 demonstrators and 2 impact studies will showcase the projects achievements and their capability to deliver innovations and secure future application advances in core markets for european society mobility green deal digital society safety and industrythe project innovations will leverage the expertise of worldrenowned industrial 5 oems 24 tier1 tier2 and technology providers and 12 research partners along the complete automotive and semiconductor value chains providing europe with a competitive edge in a growing market importantly shapefuture will contribute to ensuring european ecs sovereignty by shaping the future of ecs in mobility
sustainable and innovative manufacturing by ensuring digital green and social sme transformation

the overall objective of the project is to boost green and digital transition of european manufacturing smes through the uptake of advanced technologies and social innovation to that end mantra will create and demonstrate an effective and highly scalable europeanwide capacity building and demonstration programme to provide smes with the required assistance network of partners and experts and financial support to elaborate and implement tailored transformation journeys leading to sustainable business models and more competitive and resilience smes this innovation support ecosystem will be built on the capacities of a strong consortium and of available eu support networks and sme support initiatives
novel and scalable microbial products for regenerative agriculture

crop farmers in the eu are facing significant pains due to increasing regulations such as the eu farmtofork strategy f2f which targets ambitious reductions in the use of chemical fertilizers and pesticides these regulations will reduce dependence on foreign resources and reduce environmental damage from excess fertiliser use disruptive innovation will be necessary to protect the security of european food supply from reductions in crop yield and quality biofertilizers derived from living organisms represent a more sustainable alternative for crop yield improvement and have the potential to phase out chemicals several commercial products exist however their adoption in row crop farming is limited the majority of products are not costeffective they exhibit low shelflife perform inconsistently under field conditions and the formulations are not compatible with farming practicesto solve this nfix has developed nspire an innovative project taking an integrated approach to revolutionize the agricultural industry by transitioning from conventional farming practices to a new and scalable agronomic system the primary objective is to improve soil health and contribute to a more sustainable and regenerative agricultural sector nspire involves the integration of hydrothermal carbonization solidstate fermentation and formulation techniques into a unified manufacturing technology platform this combination yields a natural bioactive fertilizer that harnesses the synergistic advantages of hydrochar as an organic fertilizer and the capabilities of beneficial organismsnspire will have significant impacts contributing to i reducing the reliance on chemical fertilisers and pesticides in agriculture ii improving soil health while enabling sustainable productivity iii valorising agricultural residues as feedstock iv enabling carbon sequestration by converting biomass residues into stable organic compounds
domestication and adaptation in neotropical palms a microevolutionary history

amazonia is the most diverse forest on earth but it is facing a significant biodiversity loss due to increasing human pressures and climate change however the state of diversity in lowland amazonia and underlying evolutionary processes are largely underdocumented making it difficult to anticipate future changes and to elaborate knowledgedriven mitigation strategies moreover very little attention has been paid to the recent evolution of plant populations through the holocene that witnessed the rise of precolumbian societies although south america is commonly credited as a major centre of plant domestication most studies focused on a few major crops with an obvious domestication syndrome leaving aside most amazonian species with tenuous evidence of domestication dopamics will challenge the domestication syndrome paradigm in the light of incipiently domesticated palm species of ancient agroecosystems of amazonia i will build upon emblematic archaeological sites the socalled ringdicthes and implement an interdisciplinary methodology at the crossroads between ecology evolution and human sciences to illustrate the diversity of domestication histories in neotropical palms in a multispecies setting dopamics aims to retrace the precolumbian history of contemporary wild landscapes disentangle natural and anthropogenic evolutionary processes that shaped patterns of genomic and phenomic diversity with a focus on fruit metabolism and fibre biomechanics and forecast the future of palm populations under scenarios of fast genetic diversity loss eg selective logging maladaptation to future conditionsdopamics will provide extensive field observational data a fine knowledge of the microevolutionary history of domestication in neotropical palms and new avenues towards the sustainable use of amazonian landscapes to reconcile environmental concerns raised by the loss of wild diversity with local socioeconomic needs
photocatalysis as powerful tool for polyene cyclizations in supramolecular cages

biosynthetic polyene cycllization where complex structures are obtained represents an impressive example of natures a chemist organic chemists are trying to emulate the nature to develop synthetic methodologies base on these cascades it has been demonstrated that photoinduced electron transfer pet can achieve this polyene cyclizations under milder conditions as plants do during photosynthesis in this context fluorinated alcohols are very special solvents in organic chemistry due to their particular chemical and physical properties e g strong hbonding donor ability low nucleophylicity the combination of fluorinated alcohols with pet processes make this strategy unique for develop new biomimetic polyzene cyclization to achieve photocage 4 main research objectives should be implemented a design of the supramolecular cage photocatalyst and study of the interaction between them b application of the designed supramolecular cage photocatalyst to polyene cyclizations c study of the reaction mechanims d impementation and development of an asymmetric version the proposal also offers me a unique opportunity to develop transferable skills thanks to the courses proposed by saarland university and professor t gulder wich will be a valuable asset for continuing my academic career
xr media ecosystem

while media organisations increasingly support nonlinear experiences for the consumer those are still limited to single channels and media domains although several media organisations have recently succeeded in breaking data silos data sharing is mostly limited to the organisation thus there are challenges for producing content feeding multiple channels with different granularities and structures mainly related to data discovery management and reuse xreco will create a new datadriven ecosystem for the media industry focusing onfacilitating data sharing search and discovery and supporting creation of news and entertainment content in particular the creation and reuse of locationrelated 2d and 3d assets and the creation of xr experiences the ecosystem core represented by a neural media repository nmr will foster interorganisation content sharing and provide increased access to content for media creators considering novel data monetization and rights management policies a set of aibased media transformation services are built around the nmr to produce novel media and xr experiences including 3d neural reconstructions neural based device localisation image stitching derelighting and holoportation the developed technology will be validated in use case scenarios for i the news media for xrbased broadcasting and automatic and customized multitarget news publishing and for ii locationbased information and entertainment content with applications in tourism and the automotive industry
scaled ferroelectric xbars for aidriven sensors and actuators

in a multidisciplinary approach fixit aims at the development of a disruptive ferroelectric ultralow power memory and computing technology fostering the hardware implementation of novel aidriven electronic systems ferroelectricity is the most energyefficient nonvolatile storage technology fixit leverages two recent european discoveries of cmos compatible ferroelectric materials ferroelectric hfo2 as first reported in 2011 by namlab the coordinator of fixit and ferroelectric wurtzite alscn discovered by the project partner cau in 2019 our major goal is the scaling of ferroelectric synaptic devices to the 20nm regime while maintaining their analogue and multilevel switching properties moreover we aim at the integration of these scaled devices into ultradense crossbar arrays featuring nonvolatile multibit digital functionality and highly parallel multiply and accumulate operations representing the synaptic interconnects calculation at the heart of aialgorithms in our consortium we build on the vast interdisciplinary and complementary expertise of the 11 project partners 3 industries 1 sme 4 universities 3 rtos covering knowhow on material process and device development cmos integration equipment and manufacturing physical and electrical characterization tcad modelling packaging circuit design and system integration pushing european research in this topic will sustain the firstmover advantage and contribute to the european industry capability to provide advanced circuits for its needs this is inline with the european chips act where the commission has identified technological leadership in semiconductor technologies as indispensable for european digital sovereignty and decided to support the field with large investments fixit will also support europes competitiveness in semiconductors with a systematic outreach to students the training of young researchers and the building of international cooperation