Dragon09/odtu_chatbot huggingface dataset:
revealing signatures of habitable worlds hidden by stellar activity

for millennia people have wondered do other earths exist are they common would they show signs of life we now have the technical capability to answer these questions new radialvelocity spectrometers are capable of detecting the reflex motions of stars hosting earthmass planets in their habitable zones the james webb space telescope has the power to probe the atmospheres of rocky exoplanets yet the unprecedented precision of these instruments measurement capabilities is up against a fundamental astrophysicallyimposed barrier to achieving these goals contamination of exoplanetary signals by stellar activity and variability further progress is contingent on solving this variability problemreveal gathers worldleading experts in exoplanetary and stellar physics to tackle this problem in synergy we will build on recent advances in magnetohydrodynamic simulations of stellar atmospheres and datadriven efforts to separate the exoplanet signal from the stellar variability we will simulate the ground truth of the turbulent physics of entire stellar photospheres resolved at the level of individual convective cells for a broad class of stars we will model the emergent spectra of these virtual stars and observe them using the same dataprocessing pipelines as stellar radialvelocity and transitspectroscopy observationswe will continue to observe the sun and stars hosting small planets found with tess and plato the stars own spectra will reveal the clues needed to disentangle stellar variability from our measurements of their planets masses and the fingerprints of molecules in their atmospheres our unified efforts will enable the new cuttingedge space observatories and groundbased facilities to realize the full potential of their designs bringing us closer to the most profound discoveries we could hope to achieve in our lifetimes the identification of another earth or even possible signs of life on another planet
advanced magnetic components for highefficiency and highpowerdensity converters

todays magnetic components such as inductors and transformers in power converters operating at a low frequency of around 100500 khz are large compared to other electronic components these components are a major constraint limiting the miniaturization and integration of power electronic systems increasing the switching frequency can reduce the size of the magnetic components but this is generally accompanied by significant power losses i aim to address the fundamental challenges of magnetic components in the frequency range of 1 mhz to 10 mhz and the main approach will be to reduce the power loss and the component size by creating unique and innovative solutions my overall objective is to create novel magnetics technologies within conductor materials nanogranular magnetic materials and component integration that together with a new winding pattern technique will enable creation of power converters with unprecedented powerefficiency and powerdensity the specific target is to develop efficient integrated magnetic components suitable for the voltage regulator modules vrm in high performance computing systems i will demonstrate a new vrm converter that is 50 times smaller in size and 5 more efficient than current vrm products achieving successful outcomes will have a major impact on the power electronics infrastructure with the potential to reduce energy waste significantly to do this the projects research questions and hypotheses will be addressed through 5 objectives in 5 corresponding work packages 1 mitigation of highfrequency eddycurrent winding loss by creating a novel hybrid material structure2 design of new magnetic materials with nanoparticles for a low magnetic core loss3 creation of new core geometries and winding schemes in magnetics integration to handle large current efficiently4 allinone passive components integration mixing the functions of magnetics and capacitors5experimental verification and demonstration
cardiac regeneration by mrnatriggered proliferation of cardiomyocytes

heart failure hf is a major health problem worldwide because of the high number of patients and the related costs current treatments are not consistently efficacious and fail to address the major underlying cause of hf the massive loss of cardiomyocytes in damaged regions regerna has been designed to address this issue by leveraging advances in synthetic mrnas and their lipid nanoparticle lnpbased carriers to generate a construct able to reactivate mechanisms mediating cardiomyocyte proliferation in development but which are shutdown shortly after birth regerna is organised in 6 work packages that follow a roadmap towards endogenous heart repair the program starts tailoring various human assays and in vitro models such that they can reliably document cardiomyocyte proliferation these will then be used for screening pathways thought to be involved in cardiomyocyte division among which hippo is our primary candidate mrnas encoding the relevant proteins will be subsequently synthesised and engineered such that their expression is restricted to cardiomyocytes and no stromal cell expansion occurs an lnp formulation will then be developed for incorporation of the synthesized mrnas and optimized for cardiomyocytespecific delivery subsequently we will test the mrnalnp construct in our human model systems and in mouse models of myocardial ischaemiareperfusion including transgenic strains that allow unequivocal assessment of cardiomyocyte division in vivo we will then construct a gmp production line for the mrnalnp encapsulation technology to generate pilot batches for pig studies entailing catheterbased endomyocardial injection of the construct in a similar myocardial ischaemiareperfusion model the final work package will be responsible for the management and coordination of the project dissemination intellectual property management and exploitation of regerna results this program is framed from the onset to lead to a phase 1 trial at completion
food identities biomolecular archaeology reveals multiple and dynamic social identities

the major challenge of archaeological identity studies stems from the dynamic multidimensional performative and contextual nature of identities which are hard to grasp through the material remains alone to tackle the complexities of different identity manifestations one possible solution is to investigate the social phenomena that bridge both daily and special events apply to all members of a community cover different social categories and are not limited to material culture one of these is foodbuilding on the concept of social foodways foodid sets out to reveal how ancient dietary practices reflect individual and group identities through combining cuttingedge biomolecular dietary analysis with an indepth socioarchaeological contextualisation this methodological conceptualisation will be applied to eastern baltic protohistory 10001400ad ebp serving as a sociocultural melting pot of multidimensional identity dynamics due to its diverse foreign contacts intensified social stratification different religions and political powerplays by the systematic integration of welldeveloped and novel biomolecular methods applied to human skeletal remains and pottery food residues the project will reveal a unique highresolution individual dietary portraits and b intersectional social dietary profiles reflecting multiple and dynamic identity manifestations in different ebp contexts furthermore the diachronic and synchronic inter and intrasite comparisons will help to reveal the contextual and situational nature identity negotiations foodid will validate dietary practices as socially embedded and actively embodied performative phenomena that invigorate multidimensional and dynamic individual and group identities in past societies the project will advance social dietary archaeology by building synergetic bridges between the humanities and natural sciences and highlight cultural legacy of food in identity building in the past as well as today
emilie establishing a new paradigm in nanomaterials characterization

nanotechnologies have had a major role to play in the modernization and revolution of many industries such as agriculture food cosmetics medicine healthcare automotive oil and gas industries chemical and mechanical industries however the development of scientific instrumentation capable of handling such small samples and characterizing them has been lagging as a result very few nanomedicines have been commercialized so far due in part to the challenges in their characterization semiconductor fabs and chemical suppliers suffer yield reductions and profit losses due to unidentified nanoscale contaminants and unfortunately nanopollutants such as airborne aerosols with sizes smaller than 25 m and nanoplastics remain unregulated for lack of effective routine monitoring technologies resulting in unnecessary deaths 500000 yearly deaths in the eu caused by air pollution alone increased diseases nanoplastics have been linked to cancer obesity diabetes and hundreds of billions of euros in associated healthcare costs there exists a current pressing need to fill the technological gap in the analysis of nanoparticles during the nemilies eic transition project we developed emilie an innovative infrared ir analyser based on groundbreaking nanoelectromechanical sensing nems technology which pushes the boundaries of traditional fourier transform ir ftir spectroscopy by significantly enhancing the sensitivity of traditional ftirs and cutting down analysis times as well as instrument acquisition costs emilie opens an array of new possibilities in nanomaterials characterization paving the way to breakthroughs in environmental monitoring nanomedicines and more however several barriers must still be overcome to commercialise emilie and fully realise its potential the objective of this booster project is to open the pathway to the commercialisation of emilie by addressing standardization regulation and intellectual property issues
collaborative open platform for piloting services across energing smart iot and edge computing environments

the integration of edge computing advanced 5g connectivity and decentralized processing drives the widespread deployment of private edge ecosystems capable to reshape numerous industry sectors however unlocking the full potentials of edgelevel intelligent management requires concerted efforts in platform development and crosssector collaboration coppilot develops a collaborative open platform framework geared towards orchestrating endtoend services across diverse industry domainsin crafting an open platform coppilot provides a flexible solution designed to effectively manage various industry sectors while ensuring robust security automation and intelligence features regarding interoperability the framework seamlessly integrates with underlying technologies ranging from iot platforms to core infrastructure facilitating collaboration across the compute continuum furthermore coppilot empowers the development of advanced crosssector applications by offering support for cuttingedge network services thereby enabling heightened security resource management and automation capabilitiesthe implementation strategy revolves around two primary directions enabling platform implementation and real environment integration for the former coppilot adopts a modular orchestration approach simplifying the onboarding of complex applications through a userfriendly generative ai interface this approach includes integration with multitiered data processing policydriven optimization and dynamic reasoning capabilities ensuring alignment with prevailing industry standards in terms of real environment integration the platform is deployed across four large piloting clusters addressing a diverse array of edge paradigms these use cases span across energy smart city agriculture and industrial manufacturing sectors fostering the development of crosssector applications in mobility logistics and resource management
smart agriculture food innovation ecosystem

one of the main challenges of the innovation ecosystem in modest or moderate innovator regions is the lack of persistent and trustworthy cooperation between local stakeholders and external investors this gap results in an insuperable obstacle for emerging startups that have no tools and occasions to scale up and develop their businesses lacking this europe is missing the chance to brighten up the overall enterprise system as thousands of brilliant ideas dont generate positive spillovers to tackle this issue smafine goal is to create a strong ecosystem based on three main pillars1 support local stakeholders smafine will implement activities of capacity building for local stakeholder supporting the connection between innovation stakeholders and foreign investors 2 support foreign stakeholders foster the bond between foreign and local stakeholders through welldefined activities 3 cocreation with policy makers at local level and at modest or moderate innovator regions level smafine consortium is composed by 6 partners ey advisory spa deep ecosystems 500 ug rootcamp gmbh foreningen til drift af techbbq comune di matera cte matera sweden foodtech ab coming from 4 european countries and it will implement a 2 years project that aims to build a solid ecosystem in modest or moderate innovator region such the south of italy developing a testbed involving a wide participation of national and international actors as incubators accelerators companybuilders innovation agencies business clubs and networks public and private vcs and their networks national and regional authorities
learning in single cells through dynamical internal representations

cells continuously sense and interpret the external signals coming from their timevarying environments to generate contextdependent responses this is true for the entire tree of life ranging from bacteria and unicellular eukaryotes to neurons forming networks in the developing brain identifying the fundamental principles and underlying mechanisms that enable cells to interpret their complex natural surroundings and adequately respond remains one of the fundamental questions in biology conceptual views so far have been mainly guided by molecular biology descriptions suggesting that cells are controlled by a genomic program executing a prescripted plan our goal is to develop an alternative conceptual framework cells generate internal representations of their external world which they utilise to actively infer information about it and predict changes in order to determine their response we will formalise this concept in a theory of singlecell learning by combining information theory concepts to quantify the predictive information from the internal cell representations with dynamical systems theory to explain how these encodings are realised we will interrogate experimentally systems across all scales of biological organization bacteria b subtilis singlecell organisms paramecium tetrahymena and neuronal cell culture models by studying them in a comparative manner we aim at identifying generic molecular mechanisms through which singlecell learning is realised the acquired understanding will enable us to address in vivo how single neurons during d melanogaster development learn to form stabilize or eliminate axonal branches to generate stereotyped synaptic patterning under highlyvariable conditions we argue that providing a broader and generic definition of learning will serve as a unifying framework linking disparate areas and scales of biology and offering a basis for addressing fundamental biological questions
veraai verification assisted by artificial intelligence

online disinformation and fake media content have emerged as a serious threat to democracy economy and society recent advances in ai have enabled the creation of highly realistic synthetic content and its artificial amplification through aipowered bot networks consequently it is extremely challenging for researchers and media professionals to assess the veracitycredibility of online content and to uncover the highly complex disinformation campaignsveraai seeks to build professional trustworthy ai solutions against advanced disinformation techniques cocreated with and for media professionals researchers and to also set the foundation for future research in the area of ai against disinformationkey novel characteristics of the ai models will be fairness transparency incl explainability robustness against concept drifts continuous adaptation to disinformation evolution through a factcheckerintheloop approach and ability to handle multimodal and multilingual content recognising the perils of ai generated content we will develop tools for deepfake detection in all formats audio video image textveraai adopts a multidisciplinary cocreation approach to ai technology design coupled with open source algorithms a unique key proposition is grounding of the ai models on continuously collected factchecking data gathered from the tens of thousands of instances of real life content being verified in the invidweverify plugin and the truly mediaedmo platform social media and web content will be analysed and contextualised to expose disinformation campaigns and measure their impactresults will be validated by professional journalists and fact checkers from project partners dw afp eudl ebu external participants through our affiliation with edmo and seven edmo hubs the community of more than 53000 users of the invidweverify verification plugin and by media literacy human rights and emergency response organisations
understanding the textual development and the literary fortune of the book of jubilees through ages languages and across geographic regions

carefully transmitted by some and deliberately erased by others at times remembered through the centuries at others completely forgotten and vanished into the unseen the book of jubilees is a secondcentury bce apocryphal jewish text that retells the legendary foundational stories of the books of genesis and exodus with the addition of otherwise unknown details undertext understanding the textual development and the literary fortune of the book of jubilees through ages languages and across geographic regions will shed new light on the development and fortune of such an important text focusing on a literally invisible version a latin translation preserved in the undertext of a fifthcentury palimpsest ie not only a manuscript whose ink has been scraped off but a completely new written artefact refashioned through complex production processes stored at the ambrosian library in milan this latin translation has been particularly neglected by scholars but can shed precious light in relation to the hebrew original and the geez the classical language of ethiopia and eritrea translation of the book of jubilees through palaeographic and codicological analysis and by comparing different translations into multiple languages the fortunes of the book of jubilees in europe and the history and fate of this latin palimpsest manuscript will be interwoven throughout the course of the research and undertext will shed light on how divergent religious and cultural contexts have reflected variously on common texts and themes undertext will also have social and public implications triggering reflection on the extremely timely ideas of cancel cultures and will highlight the importance of the traditions of the jewish minority within the european roots and their interactions with latin language traditions
women in the domain of ritual a comparative analysis of early medieval irish lombard and frankish law texts

wisdom analyses the sociolegal roles attributed to women in three regions of early medieval europe ireland francia and lombardy from c 500 to 800 ce it takes an interdisciplinary approach to the legal texts written in latin and old irish by combining critical historical analysis comparative legal history anthropology and gender studies this allows me to mediate between law and social norm in a time where those boundaries are more fluent than nowadays its primary objective is to unravel the underlying social values and role attributions governing womens legal agency this will be done first on an individual basis due to the varying social linguistic and historical background of each region and subsequently with a comparative approach drawing out crosscultural tenets that bind together womens lives and legal thinking in the early middle ages wisdom addresses a vital area of research from an innovative vantagepoint of sources and methodological approaches as a result it will provide a novel comparative framework to specialists in legal history gender history and early medieval studies this is timely and relevant because it links to the evolution of legal thinking and generates new knowledge and interdisciplinary insights into womens experiences unearthing forgotten narratives from the middle ages that offer lessons for the present
observing modeling and parametrizing oceanic mixed layer transport processes

although crucial in determining the oceanic distribution of heat biological nutrients carbon and pollutants the circulation dynamics that governs oceanic vertical transport processes of physical and biogeochemical properties through the near surface layer ie mixedlayer ml are yet to be comprehensively quantified recently we and others have demonstrated that submesoscale currents smcs newly discovered flow structures consisting of fronts filaments and eddies have a strong influence on these exchange processes to be fully explored and characterized the high spatiotemporal variability of smcs and the complex physics that determines their interactions with other ml phenomena like surface gravity waves and nearinertial waves renders in situ measurements of these processes extremely difficult to obtain furthermore current climate models lack the grid resolution and variable forcing components required to adequately represent ml physics making it one of the greatest uncertainties in climate projections the proposed research will address this critical gap through three objectives 1 develop the numerical capability to simulate ml physics in a realistic inhomogeneous environment while resolving boundary layer turbulence and wave dynamics 2 develop a theoretical framework for a physicsbased parametrization of ml vertical exchange rates and 3 directly measure turbulent mixing tracer distribution and transport rates near smcs in situ providing the crucial observational support necessary to guide and finetune the parameterizations to achieve this goal we will extend our frontogenesis theory analyze particle and tracer concentrations in carefully designed realistic and nested largeeddy simulations and examine drifter trajectories and passive tracer spreading in multiasset field campaigns this synergistic approach will substantially impact oceanic biogeochemical modeling pollutant transport mitigation and climate projections