Dragon09/odtu_chatbot huggingface dataset:
fostering food system transformation by integrating heterogeneous perspectives in knowledge and innovation within the era

the vision of foster is to build a foundation from which a new knowledge and innovation system kis for europes food system can emerge the current structure is insufficient to address the emerging challenges of nourishing people in a healthy and sustainable way key objective is to gain insights into how it can be built to be more inclusive and better governed foster shall help to transform europes food system outcomes and will achieve this by building a foster platform including food systemstate of the art knowledge foresight by semiautomated horizon scanning trend and threatsanalysis and new multidimensional scenarios of eu food systems to 2040 implementing the foster academy including 4 summer schools for integrating food systemrelated disciplines and citizen science to enhance food system understanding across the era initiating and assessing a cocreation and colearning process within six national resp regional citizen driven initiatives cdis in which new knowledge strategies and action research agendas are gained scaling out and deep cdis solutions and approaches to other territorial contexts studying different ri mechanisms of policy support for missionoriented ri policy for food systems transformation and analysing and groundproofing them in each cdi strengthening sciencepolicy interfaces by colearning processes with external experts and developing recommendations for food systems ri policies tailored to different geographies and sectors identifying the trigger points to help unlock system lockins and support further dynamics towards system transformation and applying reflective monitoring on all fosters colearning activities to develop insights into how the kis can be broadened from an agriculturalkis to a food systemkisto inspire adoption of foster learnings over 20 workshops and a final conference will be conducted scientific position papers and policy briefs will be widely communicated
mediverseaty in quest of the human dimensions of mediterranean marine biodiversity

sustainable management of mediterranean marine biodiversity is a keypriority of eu programs and actions with the aim of integrating marine diversity protection and human development two main gaps need to be filled to achieve this goal the overall lack of understanding of european citizens conceptions and misconception on the sea the lack or oversimplification both in political and scientific debate of diversity as a key driver acting on the relationship among european citizens and marine biodiversity mediverseaty is a transnational project based on several local case studies with the aim of filling these gaps through the implementation of a doctoral network training and research program in 6 european countries it es fr el me mt a novelty in the educational and scientific panorama of marine science and biodiversity management mediverseaty develops an international interdisciplinary and intersectoral training program for 10 phd candidates who in a medium term perspective will form a community of early career researchers trained in the study of marine biodiversity via joint research projects in both academic and nonacademic settings with local and network training open science and complementary skills the project is based on two keypillars of contemporary marine sciences policies and education with an interdisciplinary approach that tackles the barriers that continue to exist among the biological sciences the humanities and social sciences and the study of environmental governance ocean literacy and marine biodiversity conservation the scientific research objectives of mediverseaty are to develop a common theoretical framework of mediterranean marine biodiversity conservation which integrates human and biological dimensions and implications to foster the crucial role of human dimensions in the protection and conservation of marine biodiversity and to make biodiversity the focus of mediterranean ocean literacy
female crossdressing in early modern and modern japan 1750s1940s

the fcdemmj project aims at investigating the urban culture of female crossdressing ie the social movement that revolved around the custom for women to wear the clothes and use the body language and the linguistic characteristics the contemporaneous culture reserved to men that existed in japan from the 1750s to the 1940s and of the control strategies japanese governments and police promoted from the 1830s to the 1940s to forbid the practicethe project is interesting as it proposes the first systematical gender historiographical study of the urban culture of female crossdressing and the opposing control strategies the project fills an important gap in the state of the art as the available scientific researches have analysed the phenomenons gender dimension only in in relation to a very restricted number of highly contextualised case studies thus producing results whose validity is limited to said case studies the project aims at filling this gap by exploring the gender dimension of the phenomenon in its entiretythe project has a strong expected scientific impact as it will allow to open a new line of research dedicated to the study of the gender dimension of crossdressing in japanese history the project has also a strong expected societal impact as lgtb rights organisations will be able to use the research results as an historical analogy to criticise and oppose current policies which restrict the gender expression of women and gender nonconforming individuals furthermore the project will produce a great benefit for my career development as it will help me obtain a tenuretrack position and create a chair in japanese sexuality and gender history
elucidating and targeting the mechanisms encoded in the genome of longlived individuals to improve healthy ageing

advancing age is the major risk factor for many serious illnesses including cancer cardiovascular disease and dementia the rising number of older individuals is thus causing a major burden of ill health however individuals that reach an exceptional old age often seem to escape or delay agerelated diseases and part of this trait seems to be encoded in their genome hence by studying the genome of longlived individuals we may be able to identify mechanisms that could be targeted for healthy ageing in the general population my previous work suggests that large genomewide association studies gwas of longlived individuals can be used to identify genetic variants involved in longevity however the common genetic variants thus far identified using gwas only explain a minor part of the genetic component of longevity this trait therefore may well be mainly determined by rare genetic variants which can be detected using wholegenome or exome sequencing of longlived families or exceptionally longlived individuals the aim of the proposed project is to establish the effect of genetic variants identified in genetic studies of longlived individuals on general health and lifespan using cellular models and subsequently model organisms to this end i will use crisprcas9 gene editing to generate transgenic cell lines and mice that harbour genetic variants in candidate genes and pathways identified through gwas and sequencing studies of longlived families and individuals i will subsequently use this information to create a highthroughput screening assay to identify compounds that can pharmacologically recapitulate the observed in vitro effects as a proofofprinciple i will start with functional characterisation of rare variants in genes involved in insulininsulinlike growth factor 1 iis and mammalian target of rapamycin mtor signalling given the wellknown role of these networks in ageing in preclinical model organisms
advancing 6gran through multitechnology multisensor fusion multiband and multistatic perception

the multix project aims to revolutionize the 3gpp radio access network ran design and operation by developing a pioneering multix fusion perceptive 6gran system mp6r that will support an integrated multisensor multistatic multiband and multitechnology paradigm to enable multisensorial perception for future 6g sensing applications the mp6r builds on top of three innovation pillars i multix perception system mps that introduces 3 levels of sensing functions into the ran stack to support multisensor multiband multistatic and multitechnology integrated sensing and communication isac following a streamlined functional split architecture to enable a fully flexible isac deployment in 6gran and to facilitate vendors to extend their ran stack to support sensing in a plug play manner
the impact of early life infections on noncommunicable diseases

a number of associations confirm that a broad spectrum of noncommunicable diseases ncds can stem from infections but evidence remains limited of particular interest are infections that occur during vulnerable early life stages as they hold the potential to trigger developmental adaptations of various organ systems with lifelong consequences the early life infections and ncds eliad project aims to elucidate the role of early life infections on ncds development by bridging existing data on infections with information on ncds and their intermediate phenotypes in children across europe leveraging the extensive resources of the eu child cohort network eliad will use existing harmonized prospective data on neurodevelopmental cardiometabolic and respiratory health outcomes linked to major ncds simultaneously the project will pioneer with the development of harmonised variables on infections in the childcohorts that is currently lacking detailed prospective information on sociodemographic lifestyle and environmental characteristics will be integrated to assess confounding mediation and effect modification of the associations analyses will particularly take into account specific age windows of susceptibility the project will create and disseminate new knowledge on links between early life infections and ncds in children and will identify vulnerable groups a key output of eliad will be the creation of a large open dataset on infections and ncds in children which will allow further investigation of causal links eg with gastrointestinal diseases indepth investigations into the underlying mechanisms and the extension of evidence into adulthood the outcomes of this research will play a vital role in shaping public health policies geared towards the prevention and control of ncds the project combines researchers skills with those of the supervisor and his team at the host institute facilitating crossdisciplinary knowledge exchange and training
enabling efficient cell engineering leaving geneexpression burden out for cell therapies and biopharmaceutical industry

mammalian cell engineering has emerged as a new groundbreaking modality for the development of cell based therapies to treat several hardtocure diseases including cancer t cellbased immunotherapies and to produce molecule with diagnostic and therapeutic applications such as monoclonal antibodies mabs that are now a dominant product class in the biopharmaceutical industry however the pipeline for efficient designtestcommercialization of the product is long and expensive even more so when cells must be engineered with two or more transgenes an increasing need in t cellbased therapies or drug production eg cells engineered to produce enzyme and coenzymes or antibody cocktails at the core of the problem is the competition for a finite number of intracellular resources transcriptional and translational that cause an unbalanced expression of products thus hampering the therapeutic effect burnout is an artificial intelligence and machine learning based software that will provide in an automated manner paired gene sequence optimisation to accelerate the process of mammalian cell engineering burnout will be validated in two different settings one for the biopharmaceutics engineered cho cell lines for antibodies production and one for cell therapy engineering t cells for multiple cars expression the successful validation of the technology will be of transand multidisciplinary interest and will have the goal of targeting the amplest variety of markets in life science from ai to synthetic biology for cell and gene therapies and global cell technologies for drug industry we envision that burnout will respond to current strategic societal needs and challenges such as reduced costs of biopharmaceutics and more effective treatment for cancer
offshore renewable and clean desalination of sea water

ocean oasis norway is a startup focused on offering a clean alternative to current desalination solutions making freshwater more available in coastal areas without large infrastructure investments our wavepowered desalination solution desalinator will mitigate the impact of seawater desalination by reducing co2 emissions and power consumption to zero our units can be installed between 1 and 5 km from shore without requiring any external power supply and safely disposing the brine without affecting the marine ecosystem each desalinator is designed for a lifetime of 25 years and our business model consists of longterm 15 years freshwater supply contracts with our customers retaining the ownership of the buoys our goal is to reach 572 units operating by 2030 with an annual production of 150 million m3 in areas where water is scarce
boosting innovation agencies for bioeconomy value chains

the overall objectives of the bioboost project are to increase the latent potential of the participating innovation agencies to learn from leading innovator regions and to cement this knowledge and experience in the organisations building and expanding networks expanding the cooperation and enlarging the participation of more diverse innovation stakeholders and territories to existing successful initiatives in the bioeconomy including agrifood forestry biobased chemicals materials and products and bioenergy the partnership will implement a range of activities via peertopeer learning including study visits and staff exchanges to develop closer relationships within the partnership and with the wider regional innovation ecosystems as well as to learn improved innovation support measures these will be cemented via operational work to build and develop innovation ecosystems and smes via hackathons and challenges 160 organisations involved by providing direct sme support on innovation management 24 crossborder kam cases and helping widening country smes towards financing of innovation projects 50 cases over 450 smes will be engaged with during the implementation of the project which will include active cooperation with 20 other innovation ecosystems bioboost connects 7 homogenous eu regions in terms of similarities of ris3 and s3 platform synergies related to bioeconomy and digitalisation the multidisciplinary partnership has been strategically selected to work in an inclusive and interactive bottomup process to discover potential new activities and identify new opportunities that emerge from this interaction despite the homogeneity in terms of regional smart specialisation the consortium consists of partners with a wide variety of complementary skills and experience covering a wide geographical area and with considerable economic social and environmental differences
advanced design of heat exchangers using multiscale models and machine learning

heat exchangers hxs are at the heart of many energy systems one example being engine cooling in the aviation industry advanced design of hxs is urgent since aircraft systems are becoming smaller and need to become more efficient through topology optimisation to and additive manufacturing am custom compact hxs will be designed to cool the engines of tomorrow although to of thermofluidic problems has recently undergone tremendous development the technology is mostly limited to academic problems since existing approaches are restricted to macroscopic design with extreme computational cost being prohibitive for industrial applicationsthe objective of adehex is therefore to propose an integrated design methodology for multiscale 3d fluidtofluid hxs using machine learningbased dehomogenization specifically i will a construct a homogenized thermohydraulic computational model b use convolutional neural networks to recover detailed microchannel design from homogenizationbased to reducing computational time by at least two orders of magnitude implemented at university of southern denmark and at the secondment brown university a twoway transfer of knowledge is guaranteed through my expertise in levelsetbased to and the expertise of the supervisors in complex multiphysics modelling and physicsbased machine learning adehex will a consolidate my academic excellence and professional maturity through new skills and competences in machine learning homogenized thermohydraulic models teaching supervision project management dissemination industrial engagement networking b harness the complementary expertise of two strong multidisciplinary teams pushing research to the forefront of design engineering and computer science and informatics c revolutionize the design process of hxs and multiphysics system optimisation while benefiting eu companies in manufacturing aviation etc and raising european economic competitiveness
empowering the future through innovative smart solutions for rural areas

futural aims to deliver a set of digital smart solutions ss under 5 smart solution domains to address pressing social and environmental challenges an integrated metasearch platform providing a onestop shop for ss will be the gateway to futurals solutions enabling search and access to ss developed by similar initiatives futural will prototype test pilot and demonstrate communityled social technological and business innovations based on the proposed ss in six rural pilot areas in the eu representing different geographical and sociocultural contexts an interdisciplinary consortium of partners and a multiactor approach will pave a coherent path towards the futural innovations through joint actions and governance systems futural will engage rural communities and pursue publicprivate interactions to develop new social practices that enable market adoption and widespread social change a clearly outlined networking euwide rural innovation forum eurif building on links with key organisations networks projects and initiatives within the european rural development ecosystem will also be developed the projects open call will fund projects that will develop their own ss based on the five futural ss domains to be applied in other rural areas and be available on the projects metasearch platform a vibrant and sustainable ecosystem will be created around futural to maximise the impact of the project the broad application of the project innovations will be enabled through the creation of business models tailored to the needs of different rural contexts and social groups policy recommendations and governance frameworks will be cocreated in multiactor workshops in the projects eurif to support among others the european green deal the european digital strategy the european pillar of social rights and the eus longterm vision for rural areas
adaptivetarget accessing haplotype variation at complex loci with optimized targeting and adaptive sampling

genetic variation at resistance loci is crucial for sustained crop yield given the challenges and increased pest and pathogen pressures resulting from a warming climate despite recent advances in massively parallel sequencing disease resistance loci and other complex genomic regions of great practical economical and scientific importance remain challenging to study the severe limitations of current methods pose a major problem for fully understanding and harnessing genetic variation for crop improvement we will develop adaptivetarget as a bioinformatic method based on targeted longread sequencing that will allow researchers and breeders to quickly efficiently and inexpensively obtain populationlevel haplotype information for complex genomic regions such as resistance genes and selfincompatibility loci in plants to explore the innovation potential of our ercfunded research we will first undertake research to test and validate the project idea validation will benefit from known haplotype data for the complex slocus supergene produced in the ercfunded project supergene to demonstrate the general utility of the method we will apply it to realworld examples consisting of complex loci of agronomic importance once the method is validated we will investigate options for patenting and licensing the method our adaptivetarget method for fast and efficient targeted sequencing of complex genomic regions could greatly facilitate assessment of genetic variation at complex genomic regions of outstanding scientific practical and economic interest therefore our method could help drive innovation in several ways by allowing the development of more efficient methods to conduct precision breeding for disease and pest resistance
health economics for policy impact

the hepi health economics for policy impact proposal utilise an existing european research infrastructure the elixir to develop the scientific integration of europe and africa in the area of health economics and to promote better integration of research in policy processes our objectives for hepi are directly aligned with the key areas of sustainable growth and jobs and peace security and governance outlined in the european union and european external action services towards a comprehensive strategy with africa specifically in the field of population health and health system strengthening we will i facilitate improved policy and research interactions in health economics and financing in africa ii foster alignment between academic and political infrastructures in health economics across europe and africa and facilitate the sharing of resources iii strengthen capacity at institutional level and iv strengthen the capability of individual researchers and policymakers to produce interpret and apply health economic evidence we will establish and expand health economics communities of practice he cops in both east and west africa these platforms will bring together stakeholders from member states policy and academic communities to strengthen health economics knowledge support the uptake of research evidence into policy and enhance collaboration on pertinent health policy issues we will align academic and political infrastructures in europe and africa in the field of health economics and lay the foundation for sharing of materials methods and data we will support higher education institutions to enhance their capacity in training highly skilled professionals proficient in health economics methods finally we will promote individual capability building by providing personalized guidance and support through a 2 year mentorship program