Dragon09/odtu_chatbot huggingface dataset:
magnetoelectric and ultrasonic technology for advanced brain modulation

the pathological alterations of neurological function eg stroke trauma neurodegeneration epilepsy neuropsychiatric diseases chronic pain are commonly associated with alterations in brain rhythms and activity patterns there is an urgent clinical need for treatments that can precisely control and restore neural activity taking advantage of stateoftheart technological developments in a variety of fields including nanotechnology nano and microelectronics novel materials brain science clinical neurology and computational modelling metabrain magnetoelectric and ultrasonic technology for advanced brain modulation brings together seven expert partners in these fields with the aim of achieving precise spatiotemporal control of brain activity using magnetoelectric nanoarchitectures that can be polarized by noninvasive remote magnetic fields this novel principle of brain activity control will minimize the amplitude of the required magnetic fields be wireless and have enhanced spatial resolution from single neurons to cortical areas we will develop a modeldriven fabrication of the coils and monitor the effects on brain function with arrays of graphene microtransistors that uniquely allow fullband recording integrating all elements in a closed loop as an alternative to remote brain stimulation we will also use novel ultrasonic technologies the metabrain control paradigm will be systematically studied in preclinical systems from individual neurons to the full brain all developments and experiments will be carried out in conjunction with theoretical models that will simulate quantify and predict optimal arrangements and patterns for the desired output translation to humans will be evaluated with our clinical partners and a detailed dissemination and exploitation plan will be developed by two expert company partners one of which has extensive expertise in the fabrication of brain interface devices with a worldwide distribution capability
charting female property and patrimonial rights in law and practice across western europe 12th16th centuries

from the mid12th century all over europe laws started to be enacted that hindered women from acquiring and managing wealth triggering a long process that on the threshold of early modernity led to a dramatic reduction in their economic opportunities the importance of the issue is undeniable not only because female agency has been a central theme in gender studies but also because the effects of these developments are still felt today yet the underpinnings of these developments are far from clear the period which is being taken into consideration coincides with a foundational phase of contemporary europe which saw profound economic social and political transformations changes in family structures and complex legal developments so why certain laws began to be enacted at this precise moment how is the cutback in female economic rights connected to the late medieval developments to what extent and how did female economic rights vary from one context to another the aim patrifem is to provide answers to these crucial questions through an innovative and extensive research covering three regions with extremely diverse characteristics in terms of legal traditions and socioeconomic and political frameworks italy france and the germanspeaking area research will involve the collection and management of large data sets it will be carried out in different archives across europe using two main bodies of sources statutes to chart the developments in property and patrimonial rights and private sources eg notarial records to observe how laws were interpreted or even preempted in practice the methodology which can be adopted for different areas across time will be instrumental to future research the data will enable to develop an interactive digital atlas which will represent an unprecedented attempt at charting a chronological geography of female property and patrimonial rights in law and practice across europe over the span of five centuries
opposites attract crosstalk between vimentin and microtubules mechanical stability vs dynamic adaptability

the cytoskeleton is mainly composed of actin microtubules and intermediate filaments it is fundamentally important for many cellular processes which is reflected in its morphological and functional diversity in the past indepth analysis of actin and microtubule networks made it possible to reconstitute their diversity in vitro with astonishing precision this enabled a detailed understanding of the mechanisms underlying actin and microtubule network formation which are the basis for many cellular processes in contrast our knowledge of intermediate filaments is still in its infancy and we are far from rebuilding complex intermediate filament networks and their interactions with other cytoskeletal elements in vitro as intermediate filaments are a major determinant of cellular resilience against mechanical stress and their mutations associate with diseases detailed insight into intermediate filament network formation and properties will represent a milestone in cytoskeletal research the proposed project will be a major step in this direction we focus on vimentin the most ubiquitous member of the intermediate filament family we will investigate the role of vimentinmicrotubule crosstalk as well as the relation between network morphology and mechanical stress how do these networks provide cells with mechanical stability while being able to rapidly change their morphology through a combination of biochemical structuring and mechanical methods we will address this question which is relevant in many biological systems from subcellular structures to tissues and organismsin this way crosstalk will pave the way towards a clearer picture of this heavily understudied cytoskeletal filament it aims at integrated mechanistic insight into the organization and mechanical functions of vimentin and its interactions with microtubules which form the basis for understanding its role in many higherorder physiological and pathological processes
wireless test fixtures to measure the dielectric properties of materials in rf

rf characterisation of dielectric materials is increasingly an important scientific and commercial activity insofar as even if a very significant effort of the rf community has allowed the development of reliable characterisation solutions it remains that these techniques rely on rf test fixtures that is heavy to implement expensive with a limited field of use type of materials frequencies resolution and therefore not adapted to the everincreasing needs of companies most of which have neither advanced skills in the field nor the equipment to implement these characterisation methods indeed the explosion of the iot and thus of wireless communication solutions has given rise to the need for companies in a wide range of sectors not only specialised in electronics and even less in rf to have a better understanding of the rf performance of the materials they use or wish to use for the fabrication of their devices for cost or supply reasons these companies are forced to use materials that are not necessarily suitable for rf or simply whose rf characteristics are not known typically plastics that under the same name may in fact have very different dielectric characteristics particularly in terms of losses and therefore pose a problem the idea of the project is to demonstrate the technical and economic viability of a new solution for rf characterisation of dielectrics this approach breaks with the techniques currently used insofar as it will make it possible to be able to characterise a larger number of materials plates solids liquids powders etc at a lower cost compared with current solutions we hope that in a few years this solution will become the reference solution for a large number of companies that until now have not access to these test fixtures
expanding the value of extracellular vesicles as carriers of biomarker and therapy in precision healhcare

extracellular vesicles evs have been identified as important signaling mediators in a myriad of physiological and pathological processes there is an emerging effort to advance the exploitation of evs in precision healthcare with special emphasis on drug delivery and liquid biopsy however the current technology readiness level in the field and lack of standardized methodology guidelines are limiting the exploitation of evs so a significant leap toward the establishment of novel tools has to be made expandevs main goal is to provide a unique solution for advancing the current diagnostic and therapeutic potential of evs by developing and implementing versatile scalable costeffective and reproducible purification systems based on singledomain antibody affinity technology for highperformance scalable evs capture in two parallel lines of research ithe system will be validated in clinical laboratory settings on breast bc liver hc and lung cancer lc by analyzing differential expression of multi omics proteomic glycomic and transcriptomic evsrelated features with the goal to develop a panel of biomarkers that would contribute in timely diagnostics enable a convenient and noninvasive prognosis assessment and tailored therapy iidevelopment of gmpcompliant protocol for producing edible plant evs as carriers of therapeutic sirna molecules their safety profile and therapeutic potential will be tested on bc hc and lc cell lines and mouse models by establishing a consortium composed of excellent research groups and smes across europe expandev will bring forth the needed paradigm shift in evs research by solving the major bottleneck issue in the field creating a simple robust cheap scalable and reproducible evs purification system will provide muchneeded technology for application of evs in personalized medicine leading the transition of evs use from a promising laboratory concept to a feasible and applicable theranostic agent
astrophysics center for multimessenger studies in europe

acme the astrophysics centre for multimessenger studies in europe addresses the ec call to provide wider simplified and more efficient access to the best research infrastructures ri available to researchers in the astronomy and astroparticle physics communities acme is set up to realize an ambitious coordinated europeanwide optimization of the accessibility and cohesion between multiple leading ri offering access to instruments data and expertise focused on the new science of multimessenger astrophysics acme will forge a basis for strengthened longterm collaboration between these ri irrespective of location collaboration and user training will be specifically aimed at levelling up access opportunities across europe and beyondacme objectives are implement the european roadmaps recommendations and act as a pathfinder to broaden improve and align access to the respective ri services and data and assess and evaluate new models for better coordination and provision of atscale services provide harmonized and inclusive transnational and virtual access to worldclass ri develop centres of expertise providing expert support to enable easier access for more researchers improve science data products management to facilitate both focused research goals and serendipitous discoveries implementing fair approaches to broaden access improve interoperable systems for rapid identification of astrophysical candidate events and alert distribution to the network of ri and scientific consortia to optimize followup observations provide training for a new and broader generation of scientists and engineers open the astrophysics and astroparticle physics data sets to other disciplines such as environmental studies or marine biology for the undersea neutrino facilities and increase citizen engagement in scientific research
wind energy harvesting for ship propulsion assistance and power

longdistance maritime transport provides 8090 of global trade but strict regulations around nox sox and greenhouse gas ghg emissions are set to cause major technological shifts whilst the pathway to achieve the international maritime organisation imo target of 50 ghg reduction by 2050 is unclear what is clear is the need to drastically reduce the industrys dependence on fossil fuels liquified natural gas lng is reaching mainstream and provides 2030 co2 reduction and other alternative fuels such as ammonia hydrogen or biofuels could decarbonise much further but face significant barriers concerning financials resource potential and acceptability in tandem considerable fuel and ghg savings could be attained by implementing efficiency measures such as slowsteaming improved ship design and utilising renewable resources with wind being a truly maritime feature the onboard harnessing of wind energy will play an important role in the decarbonization of the longdistance maritime transport industry however its uptake has been slow and there are significant challenges to its widespread adoption in the commercial shipping sector whisper will develop a novel modular retrofit solution comprising a windsolar hybrid power system to significantly reduce auxiliary engine emissions and a tilting wing sail system to provide windassisted propulsion significantly reducing main engine fuel consumption and emissions wind power will be harnessed through novel containerised turbines which will be demonstrated on an inservice container ship with efficiency savings of 153 whisper will prove the technical and financial viability of the complete retrofit solution on inservice bulk carrier vessel demonstrating efficiency savings of 298
hardwareassisted adaptive crosslayer security for computing systems

todays computing systems are facing an unprecedented security threat posed by recent attacks that use software to exploit hardware vulnerabilities as shown by attacks like spectre meltdown foreshadow and followups affecting a wide range of computing platforms and manufacturers including intel amd and arm these crosslayer attacks reach far beyond exploiting microarchitectural vulnerabilities and allow unprivileged software to exploit a variety of hardware design and implementation flaws as we demonstrated in the worlds largest systemonchip soc security competition that we have been conducting with intel since 2018 this adversarial paradigm shift sidesteps decades of security research that assumed a layered architecture where hardware is flawless and trustworthy existing solutions such as software patching or specific hardware changes are adhoc expensive or only mitigate specific known attacks particularly patching hardware after fabrication is very limited or impossiblethis proposal hydranos envisions hardwareassisted adaptive security a radically different approach to enable flexible security for future computing systems we aim to design prototype and evaluate dedicated configurable hardware inside the soc design to enable postfabrication reconfiguration of key securityrelevant hardware primitives to mitigate new attack vectors moreover we provide an evaluation framework that includes novel hardware fuzzing techniques to significantly improve existing hardwarevulnerability detection methods at design timehydranos is a game changer for trustworthy computing allows to fundamentally and flexibly tackle todays and future crosslayer attacks on securitycritical systems and provides novel research to pave the way towards futureproof security we will showcase our results on opensource hardware widely supported by academia and industry and provide it to the research community allowing open verification by thirdparties
computational analysis of peripheral literatures

the ability to attend to literary data in a variety of languages is crucial towards an understanding of literary practices across time and traditions yet few are the languages endowed with adequate computational resources for literary analysis increasing the resources enabling computational literary analysis in lesserstudied traditions is the goal of computational analysis of peripheral literatures compel focusing on galician literature a rich but peripheral tradition at the crossroads of two major romance literatures portuguese and spanish this will be an opportunity to study which features become canonical in a peripheral tradition compared to major traditions influencing it with descriptive and predictive models the project promotes a more inclusive and precise literary history via approaching a tradition little studied using computational means by concentrating on galician a language covered by the european charter for regional or minority languages the project contributes to european linguistic diversity goals beyond galician results are expected to be applicable to comparing core and peripheral literatures in other language contact settings eg the influence of french and spanish literature in catalan or french and german literature in alsatian the project will focus on two genres poetry and narrative and two main galician literature movements in the 19th century and at the turn of the 20th century public domain texts will allow us to release project resources under open licenses we will develop several methods to compare texts across literary traditions among others a supervised learning method perspectival modeling based on versification features and content features carrying out a crosslingual comparison unattempted in earlier studies by comparing a regional tradition with two major european ones compel helps promote a sense of european identity via smarter cultural heritage acess a current eu priority
privileged mobility and transnational conjugality in islamic countries reconsidering global power relations from a gender perspective in southeast asia and west africa

while attention on privileged mobility has predominantly centered on retirees tourists lifestyle migrants or obligatory shortterm expatriates scant consideration has been given to the dynamics of medium or longterm settlement linked to transnational conjugality yet privileged migrants often marry citizens of the host country and these migratory and matrimony flows are gendered whereas european women tend to form conjugal relationships with african men european men are predominantly involved with southeast asian women how can we comprehend these cartographies of desire particularly in islamic countries what motivates european men and women to establish permanent residences and families in settings where gender norms significantly differ from their countries of origin how do they adapt to these normative regimes and in what ways do they challenge power relations within the conjugal experience and their host societies furthermore how do they navigate their positions between the two countries to which they belong to tackle these issues the project privileged mobility and transnational conjugality in islamic countries reconsidering global power relations from gender perspective in southeast asia and west africa primco relies on a comparative case study encompassing the mauritanian and malaysian capitals based on anthropological ethnography sociological semistructured biographical interviews focus group and visual methods filmmaking this research critically examines the notion of white privilege shedding a light on the renegotiation of race gender and class relations within intimate and global contexts in addition at a societal level by documenting the experiences of individuals from diverse national racial and religious backgrounds who engage in relationships primco fights against racist prejudice and raises awareness of the existence diversity and richness of transnational families
centre of excellence of ai for sustainable living and working

sustainlivwork aims at creating a centre of excellence coe in lithuania for sustainable living and working sustainlivwork specialized in the development and application of ri solutions based on artificial intelligence ai in the manufacturing energy health and transport sectors this coe will act as a lighthouse with far reaching impact strengthening ri in the national and international scope nurturing from a cooperation between key national partners the four leading universities of the country ktu vilnius tech vmu lsmu and advanced international ones tau tuhh that will contribute with their knowledge to boost value creation from advanced technologies the coe is necessary to improve the low development of ai based ri solutions in the 4 mentioned sectors and to increase the sustainability of the country by developing new business models and business process solutions with lower co2 emissions using explainable ai to make those solutions safe trustworthy and transparent it will have an impact on the country and on the whole baltic sea region and beyond by the operation of 4 hubs that will derive into new educational and training programmes an enhanced cooperation with the private sector and public authorities and the creation of a lithuanian ai cluster to foster transition towards sustainability with a particular focus on the s3 priorities areas it will finally improve the lithuanian position in eu innovation scoreboards increase the international collaborations mobilise national european and other international funding programmes by creating service packages ai labs and different collaborations both national and international
how play shaped the united states from new media to politics worlding america 15032028

worlding america researches how play has been a key force in the past and present process of creating america as a coherent and hegemonic world from 1503 to the present play is an activity linked to change serious even when frivolous potentially transgressive even when rulebound play intersects with the process of worlding bringing a new world into existence in liminal moments in such unstable phases when new worlds take shape but are not yet consolidated play comes to the fore as a way to probe possibilitiesi seek out such historical moments of disruptive play when a new visual medium was introduced that contributed directly to tangible political change i study four pivotal cases worlding colonial america through engravings 15901776 worlding the nation through newspaper cartoons 18701924 worlding the body politic through television 19722022 worlding colonial mars through twitterx 20062028 tracing specific elements of play in particular imagination invitation participation and improvisation across cases i demonstrate how forms of play have been essential to american worlding in ever evolving mediascapes i hypothesize that play has intensified through the rise of social media to such an extent that current forms of worlding driven by play have overridden traditional rules of politics thus changing the game while playing iti employ sourcebased qualitative methods from cultural history media studies and american studies to synthesize these cases of hegemonic playful worlding into a comparative transhistorical framework i move beyond american grand narratives so as to understand the role of play in their construction and implementation thus contributing an innovative dimension to the composite field of american studies additionally i explore potential for counterhegemonic play