Dragon09/odtu_chatbot huggingface dataset:
fluorescent nanoagents for superresolution imaging and sensing

since alzheimer disease ad affects up to 50 of individuals above 85 we will witness the threefold increase in the number of patients by 2050 if no efficient therapy will be found the florin offers noninvasive realtime monitoring of key mechanisms involved in the ad pathogenesis by avantgarde bioimaging at temporal resolution less than 1 millisecond and spatial resolution 20 50 nm combined with the simultaneous alloptical thermal control with 20 mk accuracy florin relies on three pillars1superresolution optical fluctuation image scanning microscopy sofism and photon antibunching contrast enhanced superresolved optical imaging qism providing accurate realtime information on fluorescent nanoparticles delivery their organellespecific targeting on the molecular level and intracellular distribution with spatial resolution below 2050 nm2frequency upconverting quantum emitters that enable convert excitation in the tissue transparency window from 650 to 1350 nm to fluorescence in visual spectral range3biosensing techniques capable to detect tiny changes of temperature in the living tissue with 20 mk accuracywith its vision for the project and beyond florin will facilitate the further development of the devices for the clinical diagnosis and treatment of ad being fully in line with the eu joint programme neurodegenerative disease research and contributing to un sustainable development goal to ensure healthy lives and promote wellbeing for all at all agesuniting 6 wellrecognized academic partners from eu and canada and 3 hitech smes atomicus germany adamas usa and platformina lithuania florin action as a part of the biophotonics and quantum sensing flow will contribute to the rise of the potential of individuals and improve their career perspectives in research and innovations within this strongly networked european and global photonics material science quantum technologies and neuroscience communities
variational coarsegraining of lattice energies for crystal defects applications to partial dislocations and stacking faults

defects are omnipresent in crystalline materials and the understanding of their emergence and interaction is essential for the prediction of the macroscopic material behaviour thus there is a huge interest to pass in a rigorous mathematical way from atomistic models for crystal defects to macroscopic models eg for crystal plasticity from a variational viewpoint this can be addressed by deriving effective limiting energies from lattice energies when the lattice spacing vanishes a powerful method to carry out such a variational coarsegraining procedure is gammaconvergence in this framework we address here the variational coarse graining of lattice energies which capture the formation and interaction of defects of different dimension namely partial dislocations and stacking faults the splitting of dislocations into partial dislocations resulting in a stacking fault is a typical phenomenon of closedpacked crystalline structures thus on the one hand we aim at proposing and analysing a suitable discrete model for partial dislocations and stacking faults in hcp on the other hand we will embed this result into a broader context by investigating in a general framework the emergence of fractional vortices and string defects in xymodel type energies eventually we will characterise geometric properties of minimisers for the coarsegrained energies
center for artificial intelligence and quantum computing in system brain research

clara the center for artificial intelligence and quantum computing in system brain research represents the interdisciplinary center of excellence focused on the next generation of artificial intelligencemachine learning applications and quantumcentric supercomputing tools to push the frontier of neurodegeneration research particularly alzheimers disease the project seeks deep field knowledge and processing of largescale biological and clinical data that will enrich collective understanding of these emerging technologies solve realworld challenges thus accelerating innovations and the future of computing for the benefit of society finally building a domain specific hybrid computing and data infrastructure platform based on emerging eurohpc joint undertaking computing resources clara will significantly contribute to development of the european computing and data ecosystem in the field of system brain researchclara will be established as the autonomous division of the international neurodegenerative disorders research center indrc in prague czech republic clara is built upon a strong consortium of indrc as the coordinator with its affiliated partner vsbtechnical university ostrava the czech institute of informatics robotics and cybernetics of the czech technical university in prague and the international clinical research center of the st annes university hospital all based in the czech republic a low ri performing country with two prominent collaborative european research organizations from advanced countries paris brain institute france and leibniz supercomputing centre of the bavarian academy of sciences and humanities germany
materials design at the exascale

understanding predicting and discovering the properties and performance of materials is key to delivering the technologies that power our economy and provide a sustainable development to our society for this reason materials simulations have become one of the most intensive and fast growing domains for highperformance computing worldwide with a recognized european leadership in developing and innovating the ecosystem of quantum simulation codes max will target these lighthouse codes to address the challenges and leverage the opportunities arising from future exascale and postexascale architectures and to offer powerful paths to discovery and innovation serving both scientific and industrial applicationsmax includes 1 the core developing teams of the european lighthouse codes 2 the hpc centres designing and hosting preexascale and exascale systems 3 the main european companies engaged in the development of exascale technologies and it brings 4 a sustained record in training and educating the community and 5 in disseminating its resources under an extensive opensource model that includescodes workflows and fair datathese synergies will underpin the objectives of the present proposal that aims to upscale the max codes and their performance to multiple heterogeneous exascale architectures to endow these codes with innovative capabilities enabled by such architectures to codesign the hardware and software in collaboration with the relevant european stakeholders to enable turnkey simulation capabilities that meet the power of exascale resources and deliver the resilience needed to disseminate the entire ecosystem of codes workflows and data and to train and engage developers and users in fully leveraging such powerful instruments for discovery and innovation
isomers in oddodd nuclei

this proposal delves into the science of nuclear isomers complex quantum states with distinct energy levels and long lifetimes isomers hold untapped potential in nuclear physics and astrophysics capable of revolutionizing energy production impacting stellar evolution enhancing timekeeping and transforming medical imaging modelling isomers remains an ongoing challenge with the global interest in isomer research growing new models for the description of isomerism must be pursued with this idea in mind the proposal aims to develop an innovative theoretical framework unifying existing nuclear models specifically the algebraic interacting boson fermionfermion model with constraints coming from shell model interactions to bridge the theory gaps for resolving the mysteries of oddodd isomers this is in line with the mutual interests of the applicant and supervisoroddodd nuclei are very rich in the number of isomers but their quantitative understanding is still amiss their isomer data will be analyzed to search for the global similarities and differences in spectroscopic properties across the nuclear landscape the main goal is to quantify the decay properties lifetimes and structure of oddodd isomers particularly in shapetransitional regions where the isomeric structure gets very complex and is not yet properly understood the new theoretical tool will be generic in nature and can be used to study other nuclear physics phenomena having a longerterm influence on nuclear physics research even after the fellowship interdisciplinary and broadrange nuclear physics applications including boseeinstein condensate superheavy nuclei and isomer experiments will be established benefiting from the expertise of senior experimental collaborators at ganil surrey and london the plan envisions crossfertilisations between theoretical insights and experimental data boosting the applicants career and inspiring the scientific awareness of the public
fluidity in the medieval aristotle readers and readings of the greeklatin translations

aristotles impact on philosophy science and theology has been overwhelming especially in the late medieval and early modern periods hundreds of aristotelian manuscripts survive to attest how strongly his works belong to the written culture of the premodern intellectual world the understanding of aristotles thought was decisively shaped by latin translations from the 12th and 13th centuries translators efforts to preserve the exact phrasing of the texts and readers struggles to determine the disturbingly novel meaning lie hidden in modifications and notes in the manuscripts these have however not received the attention they deserve leading to a significant gap in our knowledge of the medieval reception of aristotle fitma aims to fill this gap through a comprehensive investigation into the new ways to read the latin aristotle with a groundbreaking focus on the textual variance in the handwritten books that preserve the translations to realize that goal fitma will produce stateoftheart critical editions of greeklatin translations of three of aristotles most influential treatises on natural philosophy de anima de generatione et corruptione and de caelo critical editions are the established scholarly means to document the variant readings in all manuscript witnesses of an ancient or medieval text the study of that variance across versions or textual fluidity provides firsthand evidence how readers were exposed to the recently available translations which are fundamentally different from their greek originals because every manuscript copy of the latin aristotle generates a different state for its medieval reception which cannot be adequately studied from the greek text or a modern translation fitma will advance the state of the art by uncovering the importance of textual fluidity in the manuscripts of these translations and developing an innovative model of interpretation applicable to other medieval translations of philosophy and science
validation infrastructure supporting remote simulations

realtime simulations rts are widely recognised as a means to support the validation process of systems and procedures up to the highest operational readiness levels and are therefore widely used to support v3 validation campaigns in the sesar context with the development of new airspace users and new air traffic management atm concepts in recent years and those expected in the near future eg uspace advanced air mobility aam vv processes have become increasingly complex with increasing demands on the infrastructures for validating these concepts and operational conditions a wider diffusion of interoperability between specialised simulators could support the need for improved atm vv infrastructures to demonstrate the achievement of validation objectives related to future european atm concepts the visors project aims at supporting a wide diffusion of interoperability standards among atm validation platforms an economic analysis of performing validation processes for atmaamuspace interoperability concepts and solutions through a multisite validation architecture will be performed an experimental demonstration test will be defined and performed to collect data for this analysis the simulation facilities of different partners of the project will be connected through a prototype platform to develop stateoftheart interoperability solutions the security aspect related to data exchange between this platform will be assessed furthermore the impact of this distribution of actors involved in validation activities on stateoftheart hp assessment methodologies will be evaluated also considering the possible remote execution of related measurements
multimodal access for intelligent airports

maias vision is that within 510 years ccam and uam based services will be available in an integrated manner with the airport infrastructure and the remaining access modes ai tools and digital twins will be used for anticipating the impacts of different service configurations on the performance of airports as multimodal hubs aviation stakeholders will be able to make evidencebased decisions on how to implement operate and regulate novel services in a way they improve passenger experience increase capacity and help reach sustainability goals the goal of maia is to develop a set of data analytics and modelling tools to support the evidencebased design and implementation of multimodal airport access solutions based on two passenger mobility innovations shared autonomous vehicle fleets and unmanned aerial vehicle fleets maia tools will monitor and anticipate passenger behaviour changes due to these new options optimise vehicle dispatching under multimodal disruptions and recommend appropriate locations for vertiports with the aim of maximising the contribution of these mobility innovations to the competitiveness and sustainability of the european aviation sector the specific objectives of maia are i identify the opportunities and risks associated with passenger mobility innovations in a multimodal airport access context ii develop maiaengine a toolset for a passengercentric design and implementation of innovative multimodal airport access services which includes new methods and tools for predicting passenger behaviour iii develop maiaccam a vehicle dispatching tool to support the operation of shared autonomous vehicle sav fleets in the airport access able to mitigate multimodal disruption impacts iv develop maiauam a vertiport site selection framework to support the implementation of unmanned aerial vehicles uav services in the airport access able to balance passenger experience capacity and environmental sustainability
quantumbased randomness processing units rpus for highperformance computation and data security

quside has developed the randomness processing unit rpu that is an innovative hardware accelerator designed for worldclass performance optimization and efficiency in stochastic high performance computing hpc and postquantum pq cryptography the purpose of the rpu is to accelerate and optimize randomized workloads which are used in countless sectors secure data transfer finance physicschemistry simulations etc all the commercial processingacceleration hardware cpus gpus tpus etc generate pseudorandom numbers prngs which are sequences of digits with certain random statistical properties in fact prng are completely predictable and therefore are inefficientineffective for randomized workloads in short the existing processing hardware are not optimized for random numbers and operations as a result customers run highly inefficient processes that impact the quality of their results and increases their costs both opex and capexour technology is brandnew the trl 7 prototype of the rpu was presented in december 2022 and protected by 14 patent families filed or granted the rpu is based on the highspeed highquality quantum random number generators qnrg chips manufactured by quside ours is one of the few companies worldwide working on this technology quside is a spinoff of the institute of photonics sciences in barcelona and our solutions have been used in the experiments awarded with the 2022 nobel prize for physics according to our financial forecasts quside will generate over 170 m in turnover and 40 m in net profit in the period 20242028 mostly from sales of rpus to customers in the public and private sectors note that this is a direct resubmission to the pitch phase as recommended by the eic jury
impact of alternative protein sources to improve nutrition

improve aims at evaluating the nutritional health safety and quality aspects together with the environmental and socioeconomic impacts of protein novel foods nfs obtained from unconventional sources in order to close the project loop by maximizing the positive impact on the transition towards healthier protein nfs the overall approach to alternative protein production in improve is based on utilization of selected agrifood and fisheriesacquaculture byproducts as primary feedstock as well as on the utilization of natural protein producers ie fungi bacteria insects micro and macroalgae the secondary byproducts formed along the value chain will be upcycled for their use in the food production cycle or for the production of process energythe obtained proteins will undergo modification and functionalization followed by a sensory evaluation and testing in food human trials and in aquaculture as feed ingredients the project will also test the feasibility of producing nf products by simulating realistic industrial scale using different methods and tools such as lca lcc ra tea and ao as well as digital twins and real time aidriven monitoring and dss tools the optimization of parameters affecting the protein nf production will be evaluated at the end to increase protein content and the impact assessment evaluated on each single stage extraction characterization modificationfunctionalization of protein rich fraction production of nfs and on the integrated processes improve nf acceptance and social relevance also through sensory evaluation actions will be assessed in four markets europe usa africa and asia to benchmark the european scenario with the rest of the world only by using an integrated approach like the one proposed in improve will it be possible to evaluate the correct feasibility in the use of alternative proteins in the food sector with a realistic sustainable approach
nanoscale electromagnetic control of advanced lubricants

friction has a crucial role in almost any technological applications accounting for more than 25 of the worlds energy consumption ionic liquids ils have been suggested as the next generation of lubricants applications of ils in reallife scenarios rely on full control of their properties in often inaccessible nanogaps externally applied electric or magnetic fields have emerged as a strong candidate to change surface polarisation of sliding solids and manipulate ils lubricating properties in such tight gaps however an exhaustive picture of the molecular processes behind electromagnetic control of friction in systems lubricated by ils is still lacking nanoecoal aims at investigating the influence of nanoscale electric and magnetic domains on the organization and shear response of model il lubricants relevant for any mechanical systems nanoecoal will use atomic force microscopy to image with subnanometric resolution structural organization of ils molecules as a function of surface electric and magnetic polarization and at the same time studying their dynamic behaviour in terms of lubricated friction force nanoscale in situ investigations will be complemented by macroscale tribology to bridge the gap between atomistic models and macroscale observations nanoecoals broader impact will support rational design of new and improved ils that can reduce energy consumption in advanced tribological applications furthermore the project will imply highly innovative direct methodological developments that can be broadly applied thus enhancing european academic and commercial competitiveness the project has a strong multidisciplinary character and will greatly benefit from the expertise the fellow acquired from his mobility and collaborations with research institutions in different countries through nanoecoal the fellow will broaden his scientific background develop complementary knowledge in new areas and increase his chances of success in academia
singleshot ultrashort laser pulse characterization based on the dispersion scan technique

ultrashort laser pulses are prominent enabling tools in countless advanced applications ranging from fundamental research to medical and industrial use however straightforward characterization of ultrashort laser pulses remains a nontrivial task the proposed project acronym sishot focuses on the development of advanced ultrashort laser pulse characterization based on the dispersion scan dscan technique we propose two dscan implementations named sshot and dshot capable of characterizing ultrashort laser pulses in singleshot operationsingleshot characterization techniques are particularly appealing because they can measure the temporal profile of individual laser pulses without artefacts often originating from averaging the proposed techniques can directly link the measured pulse parameters to the outcome of experiments for every laser shot as well as give immediate realtime feedback to the adjustment and optimisation of any ultrashort pulse laser in comparison to the competitors our instruments are easier to use and the measurements are more intuitive to interpretwithin the project the sshot will be lifted from trl4 to trl7 and the dshot from trl7 to trl9 we have identified the most important markets for ultrashort pulse characterisation the sshot will address the important scientific market at the laser wavelength of 800 nm and the dshot will focus at the wavelength of 1030 nm which is more relevant to medical and industrial applicationsthe project builds on the outcome of the previously funded erc poc project siscan it is headed by cord l arnold assoc prof at lund university in sweden and rosa romero ceo of the deeptech company sphere ultrafast photonics located in porto portugal all team members have been working with the dscan technology for many years in different collaborations including two common erc poc projects many of them are cofounders of sphere and coinventors of the patents the project builds on
science together

throughout its history rome has been a leading centre for culture and science and still today the city and its environs are home to italys largest concentration of research centres laboratories and universities in fact one of the largest concentration in europe in 2019 the sciencetogether network was established primarily just by those roman research organizations that had a longstanding tradition of interaction and cooperation among them and with international scientific contests and wanted to lay the foundation for an active collaboration also in science dissemination in these four years of joint work taught us that to make the night a more engaging and inclusive experience and address a large number of citizens and young people joining forces and collaboration is key and brings added value consequently we have developed a formula to celebrate the night a major event with researchers from all net partners institutions and representative of the stakeholder groups in rome the net village but at the same time we are also aware that celebrating the ern means feeling part of a larger european community so on the one hand we are inviting the partners branch laboratories and research centres scattered all over italy 20 cities from north to south italy to share nets objectives and contribute to a national celebration on the other hand we have searched for partnersproject stakeholders outside italy that could help us enhance the european and international dimension of the ern having based our communication strategy on marie slodowska curie as net night goodmother it has been almost natural to look at poland polish academy of sciences france marie curie museum and sweden tekniska museet national museum of science and technology the three countries that sort of represent three different stages in the scientists life