Dragon09/odtu_chatbot huggingface dataset:
earthabundant metalcontaining photosensitizers for sustainable photodynamic inactivation in plant protection and food safety

in the world the phrase we are going through a major food crisis is becoming more and more common this is because our society is faced with managing an exponentially growing world population and a decrease in arable land per person this rising demand for food in developing countries is at risk due to plant diseases induced by bacteria fungi and viruses at the same time food is traded globally enabling the dissemination of dangerous microorganisms worldwide therefore creating alternative and ecologically friendly antibacterial and antifungal treatments is essential to address the growing demand for safe and healthful plantbased foods ecopdi aims to solve this current and critical problem by developing new earthabundant metal compounds with natural ligands as photosensitizers for photodynamic inactivation pdi of resistant bacteria and fungi for this ecopdi focuses on the sustainableeconomicapplicable triple approach thus this multidisciplinary project will develop new sustainable treatments that avoid the use of pesticides and employ sunlight to activate the antimicrobial activity of the compounds will use cheap earthabundant metals and improve the disadvantages of natural compounds and apply the new photosensitizers directly to plants through the planned secondment ecopdi includes both the transfer of knowledge to the host institution and the training of the candidate in new techniques and methods the findings have the potential to open up space for additional basic and applied research on pdi in plant protection and food safety this proposal responds to the european green deal which has as its objective to restore damaged ecosystems and bring nature back across europe and reduce the use and risk of chemical pesticides by 50 by 2030
rural revival a life in the inspirational countryside

over the past few decades rural areas have experienced profound sociodemographic transformations driven by their roles in ecological digital and bioeconomic transitions these transformations further accelerated by the covid19 pandemic have led to significant diversification rendering rural regions complex and unequalsimilar in many ways to major cities thus a key problem concerns our knowledge about and perception of these places because the tools concepts and above all the public policies traditionally applied are no longer suited to address the increasing diversity of contemporary rural areas our consortium ruralitic is academically armed and wellprepared and to tackle these challenges the first step involves rethinking the rural and examining the intricate relationship between social groups and geographical spaces this conceptual requalification of what rural areas are and can be will enable the production of new scientific concepts and tools including new data surveys indicators knowledge and typologies enabling a new and synthesized view of the current dynamics and processes of change and aid in foresight for public authorities secondly these new concepts and typologies will then be deployed to analyze the drivers of attractiveness existing public policies and innovative initiatives within rural areas by implementing pilot projects and creating an initiative library well tailor recommendations to diverse social and rural contexts finally ruralitic aims to envision and produce various scenarios for europes rural future the main outcome will be a reorientation of public policies from general policies to policies tailored to different rural areas while maintaining the main orientations of european policies focusing on sustainable prosperity resilience connectivity and infrastructure
smart grading handling and packaging solutions for soft and deformable products in agile and reconfigurable lines

the conveyor system market and in particular robot segment for the automated material handling are experiencing doubledigit growth at a compound annual growth rate cagr eu manufacturers in this sector plays an important role covering 23 of the market but this technological edge is being challenged due to the astonishing growth of china japan and korea in real world many objects to be handled including food clothes bottles or plastic items are soft or deformable and robots are not yet efficient and effective in handling these objectsin this context agilehand aims at developing advanced technologies for grading handling and packaging autonomously soft and deformable products as a strategic instrument to improve flexibility agility and reconfigurability of production and logistic systems of the european manufacturing companiesagilehand will deploy 3 integrated suites 1 smart sensing suite selfcalibrating sensing solutions to grade the quality both interior and exterior of delicate objects and to produce a mesh of integrated and overlapping sensors that will improve productionline traceability agility and reconfigurability 2 selfadaptive handling sorting and packaging suite robotic manipulation systems that reacts to product quality and that can pickup and reorientated different soft and deformable products without causing product damage considering collaborative humaninthemiddle approaches 3 agile flexible and rapid reconfigurable suite a set of ai based solutions that will allow for monitoring adaptive control and synchronisation of production and logistics flows in a factory even when faced with a variability of products production mix or fresh market guaranteeing high performance in customer response time and an efficient use of resourcesthe agilehand solutions will be demonstrated in 4 industrial pilots that differ in characteristics of the surface deformability and consistency of the products to be handle
around braids categories and distances

this proposal aims at addressing classical problems about the braid group by making use of recent advances in higher representation theory more precisely i want to use khovanovseidel categorified burau representation and bappatdeopurkarlicatas work on stability conditions to work on the faithfulness problem for the burau representation and on the haagerup question for the braid groupthe faithfulness of the burau representation for the 4strand braid group is one the oldest and most tantalizing problems in braid group theory i strongly hope that new light can be shed on it by using recent tools from higher representation theory my strategy is to develop with licata a pingpong argument which will rely on a diagrammatic description of morphisms in the category of bimodules over the zigzag algebra then a fine control of the decategorification process will be needed that i will study with bonnafbraid groups also play a major role in geometric group theory a field of research that arose under the impulse of gromov amongst open questions knowing whether the braid groups enjoy the haagerup property is a central one as it has ties with several open conjectures i plan to use bappatdeopurkarlicatas work on bridgeland stability conditions on the category of representations of the zigzag algebra to build a space with walls on which the braid groups in type a would act this would yield a proof of the haagerup property for braid groups in type aboth of these work problems are major challenges in braid theory and my approach to study them will create innovative mathematics entangling tools from several fields geometric group theory triangulated categories diagrammatic algebra this project will only be made possible thanks to the help of worldleading experts in canberra and montpellier who will assist me in using mathematical tools i am not always familiar with
evolutionary cellular computing for environmental synthetic biology

this project will build living evolutionary cellular computers and showcase them as intelligent bioremediation agents current synthetic genetic networks that perform humandefined computations must remain unchangedas initially designedin order to perform well this is a problem since biological substrate adapts and evolves compromising durability robustness and computing power we will exploit the intrinsic dynamic features of living systems eccos biocomputers will be able selfadapt and reconfigure at runtime they will show unprecedented levels of robustness and efficiencyfar beyond current technological limits to this end we will tackle intracellular evolvability and multicellular reconfigurability at the intracellular level we will upgrade current genetic circuitry with predefined mutation evaluation and selection dynamics circuits will optimise themselves at the multicellular level we will design cellular consortia able to reconfigure its structuretherefore changing its functionalityaccording to environmental needs thus adaptive the ecco project will integrate theoretical developments with invivo experimentation the soil bacteria pseudomonas putida will be used as a host to illustrate the capabilities of evolutionary genetic circuits to demonstrate longrun efficiency bacteria will be used to colonize the root of the plant arabidopsis thalianaa much more complex environment than the pristine laboratory conditions where circuits are often characterized reconfigurability will be achieved by building a multicellular computer able to switch between metal and aromatic removal circuitstwo important pollutants evolution adaptation and reconfigurability are elusive to conventional computers conveniently these are intrinsic properties of living organisms the ecco will benefit from this in order to engineer living computers that unlock applications in novel domainsfrom synthetic agriculture to precision bioremediation
combined technologies for water energy and solute recovery from industrial process streams

europe aims to reach climate neutrality and a circular economy by 2050 current practices to treat industrial wastewater by large are not designed for the water valorisation and reuse and therefore are not coherent with the european ambitions to design the wastewater treatment systems compatible with the requirements of circular economy cornerstone aims at integrating novel technological and digital developments into the existing industrial wastewater treatment systems for recovery and recycling of freshwater energy and solutes the project introduces innovative principles and practices at the component level and rationally integrates the developed components to recover valuables and freshwater from industrial wastewater to achieve its objective cornerstone puts together a multidisciplinary 16partner consortium from 8 european member states consisting of large enterprises academia and research technology organisations the project targets steel pulp and paper and chemical industries as the end users due to their importance in realizing the objectives of p4planet in transforming european process industries to make them circular and achieve overall climate neutrality at eu level by 2050 while enhancing their global competitiveness cornerstone builds on the success of former initiatives and projects which have delivered technological methodological and community assets that cornerstone will convincingly and coherently leverage and advance to achieve its objectives the project designs also ensures that new developments together with digital tools can be easily deployed crosssectorial and deliver longlasting impacts to a sustainable european industrial water management approach
utilizing scatteringbased communication to gain environmental awareness in millimetre wave communication systems

this proposal contributes to sustainable internet of things iot technologies and future mobile communications with promising societal benefits the aim is to integrate energy and spectrumefficiency scatteringbased communication sc technologies into the nextgeneration communications operating in the millimetre wave mmwave band the objectives will gain better environmental awareness via enhancing the sc system performance and assisting mmwave directional transmission by attaching backscatter devices bd to the user equipment to be served the latter is a highly innovative scheme because unlike available solutions that depend on antenna hardware it utilizes the malleability of bd modulations to facilitate the estimation of directions this scheme will improve the implementational degree of freedom and potentially shorten the training period compared to the techniques that do not consider bds the core idea of addressing the problems is to examine the wireless channel altered by the bd modulation i consider that a bd applies frequency modulation to create an artificial doppler shift to the signal this leads us to investigate the delaydoppler profile of the received signal which provides information on the bd location and hence estimates the channel altered by the bd moreover applying frequency modulation with different frequency shifts on different bds will help identify multiple bds the proposal will approach the problem at a fundamental and applied level touching multidisciplinary knowledge including system and communication engineering especially highfrequency and mobile technology applied mathematics and signal processing there will be continuous knowledge transfer among the host the supervisor the collaborators and the researcher the research training will be complemented by a set of transferable skills including self and teamleadership pedagogy and communication which will make the researcher more employable across sectors
restoring the structural collagen network in the regeneration of cartilage

how can we durably regenerate damaged tissues in our body at present the answer to this question is largely unknown cellbased tissue engineering approaches can be used to produce living implants in the laboratory with a composition that is not unlike real tissues however the collagenbased matrix within such structures often lacks the specific intricate organisation that is imperative for the required biomechanical properties functionality and mechanical stability this is the cause of our inability to provide a durable cure for damaged tissues that are mechanically challenged such as articular cartilage in recoll i aim to unravel the triggers that underlie the formation guidance and integration of the structural anisotropic collagen networks in articular cartilage and leverage biofabrication technologies and biointerface engineering to generate durable implants for the restoration of damaged joints with my multidisciplinary team i will identify the biochemical physical and mechanical factors that can influence the formation and integration of the engineered collagen engineered collagen network for this purpose i will create unique in vitro and ex vivo models specifically designed for studying the organisation of anisotropic collagen networks in cartilage tissue with the generated new insights i will engineer larger tissue grafts that allow the guidance of the structural collagen organisation as well as its integration within the recipient to delineate the interplay between the anisotropic collagen networks and tissue function i will extensively evaluate the performance of cartilage grafts at the tissue and organ level through recoll i will advance the scientific field of orthopaedic regeneration by tackling major gaps in knowledge and technology to set the fundamentals for engineering more functional and stable biosimilars that can restore tissue anisotropy in patients
fostering european cellular agriculture for sustainable transition solutions

the current food system is insufficient and unsustainable generating 17 of the total ghg emissions for animal farming while only supplying 18 of the global calories and 37 of the global proteins the cultured meat cm and cultured seafood csf industry is emerging to meet the growing demand of protein with promises of lower environmental footprint however the current knowledge on the impact of this sector is limited based on developments that have not happened yet and lacking important considerations such as its social impact or its adaptability to current and future demand current racetomarket pressures fueled by recent market approvals overseas highlight the need to define a roadmap that can develop the sector in an ethical sustainable and costcompetitive way this is a unique opportunity for an effective reorganisation of the food system to establish resilient value chains in the eu gathering a large set of independent food system actors feasts will provide an unprecedented unbiased and robust knowledge base for the assessment of the sustainability aspects of the cmcsf sector by actively promoting multistakeholder engagement and cocreation activities grounded on transparent dialogue and open science practices it will explore different production methods product types supply and value chains as well as business models to provide balanced solutions that are not only sustainable by design and costefficient but also ethically responsible safe and nutritious fair and inclusive feasts designed as a thinktank adopts a food systems thinking approach and a multidimensional impact assessment including not only lca tea and slca of cmcsf products and their comparison to conventional counterparts but also systems dynamic modelling and integrated scenario analysis that will provide a decision support tool for informed policy and decisionmaking in the eu
sustainable production processing and modelling of durable additive manufactured materials for enhanced performance and longterm service in complex environments

the current industrial approach to create metal products is unsustainable massive amounts of energy consumption chemicals water and the exhaustion of natural metal resources are the hallmark of metal production and processing industries metal additive manufacturing am presents an opportunity to ameliorate metal processing and product manufacturing while this is a known fact a full scale industrial implementation of metal am has been impossible until now due to the lack of consistent am metal qualityduramat is the gamechanger that will engender longlasting performance properties of am products used in severe exposure environments duramat research will i develop am components from different alloy families sustainably ii enable am as preferred repair method for defunct metallic products and iii enable am for metal functionalisation duramats research combines experimental research with multiscale modelling and machine learning ml methodsduramat fills important knowledge gaps and will innovate am metals duplex steel alloys for marine magnesium for bioresorbable implants and coatings biocomposite and am metal coatings for corrosion and mechanical performance technologies and services am for repair ml for corrosion inhibitor selection three computational models multiscale and ml and one device addon for wire arc additive manufacturing microstructure controlthe duramat consortium consists of 6 universities 2 research centres and 5 industrial companies from 6 european countries it will train 10 doctoral candidates in a holistic approach encompassing crossdisciplinary scientific knowledge transfer teaching activities and cultivating interpersonal and transferable skillsduramats impact forecasts among others a 30 energy reduction in the processing and manufacturing of products 60 less endproduct failures reducing health hazards eco pollution and casualties and 20 cost benefit compared to conventional industry approaches
guidelines for safe and sustainablebydesign systems based on renewable hydrogen

the transition to a hydrogenbased economy necessitates a paradigm shift in design approaches traditional engineering practices must be augmented with a holistic perspective that considers safety environmental social and economic principles in the whole life cycle of the target system the safe and sustainable by design ssbd approach recently recommended at the eu level in a specific framework is the highest standard to reduce the negative life cycle impacts directly in the design phase guesswhy project aims to improve the sustainability and safety of the fuel cell and hydrogen fch systems by promoting the ssbd methodologyguesswhy will develop and publish seven ssbd guidelines of seven different fch systems covering different technology readiness level trl along the hydrogen value chain production storage and utilization selected systems are 52 pem electrolyzer sofc system alkaline electrolyzer metal hydrides storage h2 gas turbine plus pemfc and soe electrolyzer based on the existing sustainablebydesign guidelines the ssbd guidelines provide the impact assessment of the system as well as the recommendations and products concepts for safe and sustainable impact improvements along the whole life cyclethe project will start collecting inputs from previous projects stakeholders and literature the guidelines will be developed following a standard process product definition initial impact assessment idea generation and scenario and benchmark analysisdissemination and exploitation will target both the regulatory field and the industrial stakeholders to promote the utilization of the guidelinesguesswhy consortium is composed of universities and research centers expert in safety and sustainability assessments and by private companies with expertise in the design and production of fch systems guesswhy is supported by a network of public bodies and industries interested in providing inputs and disseminating project results
fmo1 multifunctionality for improved plant health

flavincontaining monooxygenases fmos are a highly conserved family of enzymes present in prokaryotes fungi animals and plants among plant fmos the nhydroxylating fmo1 is essential for pathogen resistance fmo1 catalyses the biosynthetic reaction to synthesize nhydroxypipecolic acid npip the critical signalling molecule for systemic acquired resistance sar defense priming since the identification of fmo1 functionality in 2018 targeted analysis of the npip pathway shows high potential for metabolic engineering to enhance disease resistance in dicotyledons a fully analogous role for npip sar in monocotyledonous crops however is less clear in fact preliminary analysis by the neilson group ucph suggests the fmo1 from barley hordeum vulgare and sorghum sorghum bicolor has diversified functionality compared to activity observed in the fmo1 from arabidopsis unbiased analysis of potential fmo1 multifunctionality has not yet been addressed and detailed analysis of fmo1 evolution throughout the plant kingdom is lacking the proposed project multiply fmo1 multifunctionality for improved plant healthwill employ an interdisciplinary approach to investigate the evolution and functionality of the significant plant fmo1s specifically this project will combine bioinformatics phylogeny reconstruction protein modelling and docking with enzyme kinetic studies and in planta analysis to assess fmo1 multifunctionality throughout the plant kingdom the in planta fmo1 characterization will primarily occur in barley to unravel the mode of sar in these agriculturally important crops in addition multiply is designed to utilize my background in protein biochemistry and bioinformatics i will also receive significant training within the new technical fields of metabolomics and plant physiology as well as scientific management leadership and mentorship to establish an independent research group in academia