Dragon09/odtu_chatbot huggingface dataset:
elucidating the underwater adhesion of the brown algae fucus vesiculosus

many marine organisms of the intertidal zone like mussels barnacles and various algae must form strong attachments to the substrate in their environment in order to resist forces of crashing waves therefore they evolved highperformance underwater adhesives which are able to stick to various surface chemistries a feat unmatched by current glues on the market understanding the chemistry and formation process of these adhesives has great potential for the development of synthetic underwater glues which are of high interest for medical and industrial applications here i propose to conduct research on the underwater adhesion of the brown macroalgae fucus vesiculosus analyzing its composition structure and adhesive properties for this purpose the early formation process shortly after the fertilization of fucus egg cells will be analyzed using a combination of traditional histology and advanced electron microscopic and spectroscopic techniques once key building blocks have been identified their dynamic secretion and assembly process will be followed over time additionally the curing of the adhesive and the involved crosslinking reactions will be investigated after different time points elucidating key chemical principles of the complex formation of this underwater adhesive has the potential to inspire the development of novel and sustainable adhesives with a wide range of applications
quantumenhanced shadows scalable quantumtoclassical converters

largescale quantum experiments do not work in isolation substantial classical computing power is required to control the experiment and process the results this necessarily creates informationtransmission bottlenecks at the interface between quantum and classical realms these bottlenecks create scalability issues that prevent us from using existing architectures to the best of their capabilities and may even impair our ability to further scale up system sizesin this project we adopt a unifying framework that takes into account all computing resources quantum and classical we develop quantumtoclassical converters to overcome informationtransmission bottlenecks dubbed shadows they leverage randomization as well as quantumenhanced readout strategies to obtain a succinct classical description of an underlying quantum system that can then be used to efficiently predict many features at once the shadow paradigm is compatible with nearterm quantum hardware and utilizes genuine quantum effects that do not have a classical counterpart building on these ideas we also establish rigorous synergies between quantum experiments and classical machine learning shadow learning protocols use shadows to succinctly represent training data obtained from actual quantum experiments a classical training stage then enables datadriven learning of genuine quantum phenomena finally we develop new tools to ensure reliable execution on current quantum hardware thus bridging the gap between theory and experimentmy interdisciplinary skill set combines methods from modern computer science with quantum information and has already led to numerous highimpact contributions eg 1 nature physics with more than 350 citations and 2 science publications these insights form the basis for this larger project where we lay the foundation for scalable and practical quantum data processing and learning that can keep up and grow with future improvements in quantum technology
exercised breastmilk a kickstart for childhood obesity prevention

innovative preventive strategies are urgently required to halt the rising prevalence of childhood obesity given the inefficacy of current interventions mothertochild transmission of obesity accounts for a large proportion of childhood obesity more than what can be explained by genes nutrition during the first 3 months of life is crucial with rapid weight gain in this period associated with subsequent obesity breastmilk is considered optimal for infant nutrition but its composition depends on the mothers metabolic health the concentrations of some breastmilk compounds linked to infant obesity are associated with maternal body mass index maternal lifestyle factors such as diet can alter breastmilk composition little is however known about the effect of exercise during lactation exercise is a major regulator of systemic metabolism affecting multiple tissues and organs in this ambitious interdisciplinary project i will determine how exercise during lactation influences breastmilk composition in women with overweightobesity and whether exerciseinduced changes in breastmilk will influence infant obesity risk my preliminary data show acute effects of exercise on breastmilk concentrations of adiponectin and lipid metabolites relevant for energy metabolism in exmilk i will determine both acute effects and adaptations after regular exercise on a complex matrix of breastmilk compounds by linking breastmilk data to comprehensive data for the infants i will investigate the potential mechanisms underlying the effects of maternal exercise on infant obesity risk mediated by changes in breastmilk composition to reach my goals i will perform goldstandard randomised trials and analyse biological samples from mothers and infants on multiomics platforms my experience in metabolomics and exercise intervention trials in reproductiveaged women will enable me to break new ground in understanding how exercise during lactation modifies infant obesity risk
selfimposed restrictions understanding why politicians adopt anticorruption policies

corruption is a pressing global challenge which imposes substantial costs on the lives of people and businesses and undermines citizens trust in democratic institutions anticorruption reforms and political ethics regulation have also grown dramatically in european countries but display varying degrees of success while scandals policy diffusion and political will have been advanced as explanations for the success or failure of anticorruption policies it not yet understood under which specific conditions politicians will adopt anticorruption policies acps aimed at changing their own status quo and conduct if we dont know the answer to this question then anticorruption efforts are doomed to failure unlike previous studies that focused on the implementation of broad anticorruption reforms in the public sector or on the behaviour of participants acting out the part of policymakers in controlled laboratory experiments the novelty of the sir project is that it will investigate the specific conditions that surrounded the adoption of each anticorruption law aimed at political officials namely party funding conflict of interest and lobbying the focus on policies will allow the research to go beyond simple national variations and grasp the conditions under which the policies were adopted in any given time this research will be divided into two phases i the creation of an original database with the contextual conditions surrounding the adoption of acps and the adoption of greco recommendations in eu countries ii quantitative and qualitative comparative analysis of the contextual conditions surrounding the adoption of each specific acps dedicated to political office holders
resolving ambiguities in flow boiling within micropassages integrated modeling and experiments

electronic products are progressively smaller and more powerful resulting to an exponential increase in the generated residual heat their effective and environmentalfriendly cooling is therefore of upmost importance for many applications such as data centres fuel cells insulatedgate bipolar transistors lithiumion batteries and photovoltaic cells with a market value of several billions of dollars worldwide flow boiling within micropassages has been proven as one of the most efficient cooling strategies for such highpower density electronics however such solutions are not yet commercially available this is due to a lack of a deep understanding of the underpinned flow and transport processes and unresolved ambiguities in microscales and hence of reliable and easytouse thermal design tools for smallscale components refine aims to give light at such crucial ambiguities utilising a synergic combination of novel volume of fluid vof based numerical simulations and tailored highresolution experimental diagnostics dr andredaki will develop a novel cuttingedge simulation tool starting from an already enhanced vof solver that she has been developing in the last years this will be validated against parallel advanced experimental measurements on flow boiling that she will perform using single and multiple parallel microchannel heat sinks the final optimised and validated numerical solver will then be applied for a wide series of parametric simulations that in combination with additional laboratory measurements will form a unique database that will lead to the development of novel physicsbased design correlations for flow boiling microchannel heat sinks the wordleading expertise of prof moreira who will supervise this project on the experimental techniques for microscale boiling guarantees the highest level of knowledge transfer enabling dr andredaki to further develop her skills and enhance her future career opportunities in academia
elucidating the crosstalk between the immune system and brown adipose tissue in humans

brown adipose tissue bat is a promising therapeutic target to improve cardiometabolic health however bat metabolism is dysfunctional in obesity hence it is highly relevant to ascertain which mechanisms modulate bat function and how it can be improved in this contextmice studies indicate that the immune cellsbrown adipocytes molecular interactions within bat modulate its function indeed mice knockout for the transcript mecp2 in bat macrophages show impaired bat function and develop obesity further cold acclimation activates specific subsets of infiltrated immune cells which improves bat function altogether points to infiltrated immune cells as key players regulating bat but their identity and role and if they can be targeted to activate bat in humans is unknownthe main questions we aim to tackle are i which are the immune cell populations within human bat ii does local inflammation exist in bat of obese subjects is it related to their disrupted bat oxidative and metabolic capacity iii is the bat oxidative and metabolic capacity improvement after a 3month cold acclimation driven by changes in bat immune cell profile to answer these questions immunobat will characterize the immune cell profile of bat in lean and obese subjects using novel singlecell omics in samples obtained by neck surgery bat oxidative and metabolic capacity will be assessed in vivo by stateofart methods combining the use of 15oo2 and 15oh2o pet measures with in vitro mitochondrial respiration assays of brown adipocytes these measures will be repeated in obese subjects after a 3month cold acclimation the most powerful stimulus to activate batimmunobat will provide new mechanistic insights into obesity pathogenesis at the same time that it expects to find new tools to improve cardiometabolic health by activating bat further it will promote the fellows training in adipose biology and immunology and his growth as an independent and mature researcher
cognitive edgecloud with serverless computing

edgeless is set to efficiently operate serverless computing in extremely diverse computing environments from resourceconstrained edge devices to highlyvirtualised cloud platforms by taking advantage of aiml solutions it will enable automatic deployment and reconfiguration to fully exploit compute resources available on clusters of nearby edge nodes edgeless will define novel orchestration systems that provide a flexible horizontally scalable compute solution able to fully use heterogeneous edge resources while preserving vertical integration with the cloud and the benefits of serverless including its application programming model it will address edge systems at design stage particularly targeting lowlatency highreliability applications with computationallyintensive tasks requiring specialised hardware or a trusted environment this ambitious challenge will be met via distributed computing solutions to partition the edge environment in clusters each managed as a local decentralised serverless platform in each cluster orchestration and scheduling of jobs will run smoothly thanks to realtime monitoring of shortterm loadnetworkenergy conditions and anticipatory aipowered algorithms to manage lightweight virtualised lambda executors eg unikernels environmental sustainability will be boosted by dynamically concentrating resources physically eg by temporarily switching off faredge devices or logically eg by dispatching tasks towards a specific set of nodes at the expense of performancetolerant applications clusters will cooperate with each other and with all the layers in the edgecloud continuum to compose complex applications ondemand through a faas paradigm edgeless innovations will be validated through testbeds nearedge mec and two smalldevice lab setups integrated through a federated edgecloud infrastructure and three pilots autonomous smart city surveillance internet of robotic things and healthcare assistants
new european bauhaus solutions in food living heritage and conviviality

convivium is an interdisciplinary and intersectorial coalition of public and private european partners working together to bring a cultural dimension to the european green deal through the leveraging of the material semiotic and symbolic power of food the consortium sees food cultures as a living heritage that reflects changes in society and contributes to local wellbeing with widereaching impacts convivium mobilizes numerous creative and transformative forces in the fields that inform the new european bauhaus to ensure sustainability and positive societal transformation through the medium of food heritage it offers attractive and sustainable culturalbased solutions which will bring about a range of cultural and economic applications available to different target groups they include architectureanddesignbased prototypes that will support farmers and agricultural cooperatives to work in symbiosis with the environment with tradition and with stateofthe art advances cultural events and interventions that bring food the arts and the humanities together to positively change the mindsets of food producers and consumers new organizational models that champions intercultural generational and intersectional visions through the medium of food across local populations and digital tools to reinforce the presence of food heritage in institutions such as museums and historical sites convivium will achieve this commitment supported by solid managerial scientific collaborative and technical structures which are in constant dialogue to ensure that the unlocking of food heritage translates into solutions grounded in the needs and opportunities of local communities in stateoftheart social science and humanities approaches and methods and in synergies between traditional crafts and cuttingedge technological developments
using lake sediments to reconstruct soil weathering trajectories over the holocene

chemical weathering is a central biogeochemical process that shapes the earths critical zone cz regulates the global carbon cycle and sets the pace for nutrient delivery to soils and ecosystems most knowledge on the rates and controls on chemical weathering are from laboratory experiments and from the shortterm observation of modern soil and river systems in contrast little is known about past changes of chemical weathering over hundreds to thousands of years which limits our understanding of how longlasting humanclimateecosystem interactions have impacted the cz trajectories because of this knowledge gap it is not possible to fully understand the response and feedbacks of the cz to the climatic and environmental perturbations of the holocene period nor to predict their future evolution during the anthropocene to fill this gap lakeswitch aims to produce new quantitative weathering records over 102104 year timescales with a temporal focus on the holocene period there are 3 main challenges 1 developing quantitative proxies of chemical weathering 2 calibrating these proxies for paleoreconstructions 3 measuring these proxies in paleoarchives of 102104 year timescale integration to provide these records we will measure lithium and strontium isotopic proxies in lake detrital and authigenic carbonates and biogenic silica sediment archives to calibrate these proxies and archives we will use a sourcetosink approach and track weathering product pathways from soils through rivers to lake deposits then we will apply these proxies back in time in holocene lake cores as rapidlyeroding mountain dominate the global chemical erosion budget we will focus on the study of the european alps new data from alpine watersheds and lake records spanning gradients in erosion runoff and land use will serve to quantify and model the impact of climate and human drivers on soil trajectories from the onset of the holocene to the anthropocene
fliara femaleled innovation in agriculture and rural areas

key contemporary trends such as climate change gender inequalities and the covid19 pandemic bring new challenges to european rural areas change also brings opportunities to foster more resilient inclusive and sustainable rural regions such as created by the digital and ecological transitions however there is a need for all individuals and communities to participate in rural innovation traditionally however rural womens employment opportunities and contribution to innovation has been overshadowed and often suppressed by for example a patriarchal ethos fliara femaleled innovation in agriculture and rural areas uniquely proposes a transdisciplinary innovative methodology to improve understanding awareness and recognition of womens role in a more sustainable rural future as well as develop proposals for how more effective policy and governance frameworks can support this and enhance womens capacity to contribute to it fliara will combine futures and case study methods alongside network building and policy benchmarking while being underpinned by a cocreated conceptual and assessment framework using a unique foresight approach fliara will identify visions for sustainable farm and rural futures and the sustainability innovations needed to realise these visions using a thematic casestudy approach project partners will investigate womenled innovations on farms and in wider rural areas looking at their pathways in the innovation ecosystem building on the power of social networks a community of practice will be developed with women identified throughout the case studies networking alongside key innovation policy and governance stakeholders the community of practice network will occur in conjunction with a campaign of visibility for womenled rural innovations spotlighting women as key innovation actors project outcomes will result in enduser ready resources including policy proposals and practical tools supporting womenled innovation
nanocarbonionic liquidinterfaces for catalytic activation of nitrogen

ammonia is one of the most important chemicals in the world electrocatalytic reduction of nitrogen nrr at ambient conditions is a sustainable alternative for its production to the established energy consuming haberbosch process relying on hydrogen from fossil sources the triple bond in dinitrogen is one of the most stable covalent chemical bonds conversely the dissociation of dinitrogen and its chemical conversion is highly demanding nrr is a carbonneutral and decentral process that can be carried out wherever renewable electricity water and air are available however current research on nrr and other electrocatalytic reactions has reached an impasse as improvements based on catalyst design are getting more and more incremental at this tipping point cilcat tackles a foreseeable stagnation by constituting a disruptive principle that holds holistic perspectives for the activation of small molecules the novel concept will go beyond established principles of isolated catalytically active sites by confining ionic liquid il electrolytes into charged porous carbon materials an interface will be created that as a whole serves as catalytic surface cilcat will contribute to a fundamental understanding of the physicochemical principles of sorption into ils upon confinement in pores targeted catalyst development will follow and the possibility of using the principle for catalytic activation of nitrogen and other molecules will be explored this innovative approach will then be combined with advanced electrode design cilcat aims for more than a step towards a future carbonfree nitrogen economy it is a pioneering attempt to heterogenize homogenous catalysts by rather converting the energy principles of small molecule activation than chemical structures from solution to surfaces the methodology is transferable to other obstacles in the field of catalysis and the project will lead to a more objective general understanding of reactivity in confined spaces
controlling delocalisation and funnelling of excited state energy in the strong coupling regime in molecular systems

a fundamental physical property of a fundamental physical property of matter is its ability to interact with light this is not only the basis of fascinating concepts like seeing colours but also the foundation of life and advanced technologies yet some basic physical laws hamper possible utilisations it is therefore of great importance to examine how to bend these laws how to bypass them and by so doing open up new opportunities for novel applications this is exactly what this project aims to doplant leaves are green because they absorb visible light however it is less known that this lightmatter interaction can be enhanced to the point where it is so strong that the photon and molecule cannot be regarded as separate entities but as a combined system with unique properties nature uses strong pigmentpigment interactions to rapidly funnel absorbed sunlight to the photosynthetic reaction centre however up to now organic solar cells do not take advantage of such quantum processes to enhance light to electricity conversionin control i will use a chemical viewpoint to develop unique molecules optimised for strong lightmatter interactions and with these examine excited state processes of strongly coupled systems my aim is to funnel excitation energy to charge transfer states in an organic heterojunction using the delocalised nature of hybrid lightmatter states this interaction enables transport of excitation energy over distances much longer than have been previously considered feasible using timeresolved optical spectroscopy and photoconductivity i will systematically analyse the interaction between delocalised hybrid states and localised charge transfer states allowing design criteria to be formulated the outcome of this research program will be the description and mechanistic revelation of a novel quantum physical phenomenon that can enable development of organic solar cells from simple layered structures with unprecedented efficiencies