Dragon09/odtu_chatbot huggingface dataset:
functional piezoelectric nano composite fibers for smart drug delivery

the development of controlled drug delivery systems has been extensively investigated to improve the therapeutic efficacy of conventional drug products the control over biodistribution and pharmacokinetics is critical to enhance the efficacy and minimizing the side effects of therapeutic agents an ondemand drug delivery system for precise control over the release time and the quantity of drugs is needed which has not been studied comprehensively and remains to be explored piezoelectric materials provide a superior platform for the electrically controlled drug delivery system due to their ability in converting mechanical forces to electric potentials through the direct piezoelectric effect the importance of this project is the contribution of the piezoelectric effect on drug loading and release this project proposes the mechanoresponsiveness of piezoelectric electrospun nanocomposite fibers for drug delivery applications the novelty of the project is adding twodimensional 2d ferroelectric nanofillers to the composite to enhance piezoelectric efficiency which leads eliminating additional posttreatment processes poling reducing fabrication complexity and cost the large surface area inherent to nanomaterials fibers porosity together with the transformative piezoelectric properties allow electrospun fiber to be a drug delivery platform driven by the piezoelectric effect the drug release quantity will be tuned by a mechanical stimulus in invitro conditions this project will demonstrate the utility of piezoelectric nanocomposite electrospun fiber for mechanoresponsive controlled drug release and its potential for invivo applications in a facile manner in the futureten years of experience and knowledge in functional fibers that come to this project by the applicant will strengthen the ku leuven lead in smart fibers based on piezoelectric materials for a wide range of applications not only in biomedical applications but also in wearable technology
plurilateral integration agreements and noneconomic objectives

this project revisits the centrality of trade agreements as a mechanithis project revisits the centrality of trade agreements as a mechanism for international cooperation intervention in international trade and investment increasingly is motivated by noneconomic objectives fighting climate change national security safeguarding societal values complementing economic competitiveness objectives multilateral agreements to reduce associated competitiveness spillovers are constrained by geopolitical and geoeconomic rivalry as are trade agreements that span the major powers states have begun to pursue cooperation on a smaller group plurilateral basis these differ from trade agreements by focusing on specific policy areas and potentially being open to many countries research has devoted little attention to understanding the operation impacts and political economy of plurilateral integration initiatives the project aims to fill this gap through conceptual analysis of the incentives to cooperate on a plurilateral basis building multicountry panel datasets documenting the use and purported goal of trade investment and industrial policies and empirical analysis of the economic incentives for plurilateral cooperation on tradeinvestment and regulatory policies assessing tradeoffs between noneconomic and economic objectives and the size and incidence of crossborder spillovers associated with policies favoring domestic industries or discriminating against foreign producers indepth case studies of domainspecific plurilateral initiatives will investigate effectiveness in attaining stated objectives and reducing spillover costs of national policy instruments these analyses are complemented by surveybased research to investigate the preferences of key actors and stakeholders for issuespecific plurilateral agreements as opposed to trade agreements a synthesis monograph will distil the implications of resulting findings for the multilateral trade regime
multimodal chemical probes as diagnostic tools

the overall goal of this project is the detection and imaging of the serine protease tmprss2 the first chemical part focuses on the design and synthesis of multimodal chemical probes to visualise serine proteases in particular tmprss2 the then obtained smart activitybased probes will be used to complete the goal of the biomedical part of the project which is of tmprss2 in a mouse model for colorectal cancer crc and in blood samples of crc and prostate cancer patients successful execution will lead to new diagnostic tools to detect tmprss2 the chemical tools will be readily applicable to other serine proteases as well whereas the specific tmprss2 probes may also be used in other cancer types
comprehensive photophysical study of leadfree halide perovskite nanocrystals towards ecofriendly and highperformance lightemitting diodes

this project pholed will concentrate on leadfree halide perovskite nanomaterials for their lightemitting diodes leds application to address the current lowperformance issue the focus of this project will be the synthesis of novel leadfree layered halide double perovskite nanocrystals with surface engineering and the corresponding mechanism studies which account for the fabrication of highperformance perovskite leds peleds pholed will combine multidisciplinary research crossing synthetic chemistry surface chemistry electrochemistry photophysics and optoelectronics the completion of pholed will result in the generation of new knowledge to synthesize novel leadfree perovskite nanocrystals with outstanding optoelectronic properties which can provide crucial hints for chemists to enable further optimization of highquality leadfree perovskite nanomaterials an achievement of lowcost and highperformance leadfreebased peleds from pholed will significantly highlight the possibility of the replacement of conventional leds that are made of exotic semiconductors such as gallium arsenide and gallium phosphide the replacement of toxic lead by less or nontoxic leadfree metals achieved by pholed will also have benefits for both environment and human beings this fellowship will allow the researcher to incorporate the study of emerging leadfree perovskite nanomaterialsbased leds into his research profile broaden his knowledge and offer the researcher further expertise in the fields of ecofriendly lowcost and highperformance peleds opening new horizons for expanding his career prospects new technical skills and expertise obtained during the fellowship in the beneficiary institute will strengthen the researchers experimental capabilities and exploit new opportunities in multidisciplinary research domains this fellowship will also broaden the researchers networks with worldleading groups in the research of metal halide perovskitebased leds
everything you always wanted to know about the jko scheme

the project deals with the socalled jordankinderlehrerotto scheme a timediscretization procedure consisting in a sequence ofiterated optimization problems involving the wasserstein distance w2 between probability measures this scheme allows toapproximate the solutions of a wide class of pdes including many diffusion equations with possible aggregation effects which havea variational structure wrt the distance w2 but not wrt hilbertian distances it has been used both for theoretical purposesproving existence of solutions for new equations and studying their properties and for numerical applications indeed it naturallyprovides a timediscretization and if coupled with efficient computational techniques for optimal transport problems can be used fornumericsthis project will cover both equations which are wellstudied fokkerplanck for instance and less classical ones higherorderequations crowd motion crossdiffusion sliced wasserstein flow for the most classical ones we will systematically considerestimates and properties which are known for solutions of the continuousintime pdes and try to prove sharp and equivalentanalogues in the discrete setting some of these results lp sobolev bv have already been proven in the simplest cases theresults in the classical case will provide techniques to be applied to the other equations allowing to prove existence of solutions andto study their qualitative properties moreover some estimates proven on each step of the jko scheme can provide usefulinformation for the numerical schemes reducing the computational complexity or improving the quality of the convergenceduring the project the study of the jko scheme will be of course coupled with a deep study of the corresponding continuousintimepdes with the effort to produce efficient numerical strategies and with the attention to the modeling of other phenomena whichcould take advantage of this techniques
animals and society in bronze age europe

this project will create a new vision of bronze age ontologies by exploring the role of animals as active participants in bronze age social worlds the impact of contemporary capitalist ideology on archaeological understanding of the european bronze age has been profound dominant narratives describe a world in which economic intensification the accumulation of wealth and the emergence of chiefly hierarchies were predicated on the objectification of the other this project will critically reevaluate models that view animals as objects of exploitation drawing on work in animal studies that highlights how living with animals involves intimate interaction and interdependency it will investigate the intertwining of human and animal identities and will consider how the social and cultural significance of animals affected how they were farmed managed and consumed the appearance of fieldsystems and houses incorporating byres for cattle indicates major changes in animal management in the bronze age yet animal iconography and the presence of animal remains in graves and votive deposits suggest that animals had cultural significance the project will bring together contextual zooarchaeological isotope organic residue and adna analysis to investigate humananimal sociality examining herd management patterns of humananimal interaction animal mobility and exchange the role of animals in feasting and ritual and their location in cultural taxonomies by examining the ontological position of animals not as passive objects but as active subjects this project will radically reframe the theoretical basis on which wider interpretations of the bronze age are based including how political authority gender relations and economic activities were structured by illuminating alternate modalities of power and agency and different ways of living with nonhuman others it will also contribute to current debates around issues such as sustainability in the present
graphene mxene and ionic liquidbased sustainable supercapacitor

a paradigm shift in energy storage technology is needed to support the transition towards the climateneutrality set by the eus international commitments under the paris agreement while ensuring the targets of eus action plan on critical raw materials crms in this context greencap joins a multidisciplinary consortium with 5 universities 1 rd institute 6 companies located in 7 european countries including italy germany france ireland united kingdom estonia and netherlands and 1 noneu country ukraine to unlock the full potential of supercapacitors scs as electrochemical energy storage systems we will develop a crmfree technology exhibiting a batterylike energy density 20 whkg 16 whl together with the distinctive superior power densities and high cycle life of traditional electrochemical double layer capacitors greencap will exploit layered 2d materials including graphene and mxenes as electrode materials and ionic liquids ils as highvoltage electrolyte the main objectives of greencap are i to synthesesfunctionalize graphene and mxenes via facile scalable and sustainable crmfree methodologies assuring both high surface area and ion accessibility introducing faradaic charge storage mechanisms and improving their quantum capacitance ii to produce novel nonlowtoxic and nonlowflammable ilbased electrolyte with high conductivities and a high electrochemicalthermal stability ensuring sc operation at voltage 35 v within 50c to 100 c temperature range thus eliminating the need for sophisticated cooling systems iii to validate the novel sc technology at industrial scale by fabricating cylindrical cells at a trl 6 while ensuring the creationexistence of the complete value chain from material to cell producers iv to produce a novel supercapacitor management system enabling the full potential of the greecaps scs in highend applications and ensuring their integration into the circular economy
somohomo inversion for chiral openshell piconjugated systems

organic materials are of strong interest for increasing the performances of modern electronic devices oled photovoltaics transistor while reducing their overall cost in comparison to classically used rare and precious metals and semiconductors in this domain chiral piconjugated molecules have recently opened new directions due to their specific interaction with circularly polarized cp light and their unique electron spin filtering ability known as chiral induced spin selectivity ciss effect related to the molecular magnetic moment these properties have been only investigated for closedshell chiral systems with weak magnetic property which currently limits the potential of chiral molecules as spinfilter organic materials designing openshell chiral organic materials with high magnetic property such as in organic highspin diradicals appears therefore a promising direction for the future breakthrough of optoelectronics by controlling both electronic and spin properties however synthetizing organic chiral diradicals remains a considerable scientific challengedue to their high chemical reactivity and the difficult control of their magnetic properties accordingly the molecular combination of chirality and diradical state remains relatively unexplored fundamentally poorly understood and unknown for chiral photonic and magnetic applications in this project i will design unprecedented stable organic chiral di and polyradicals where the singly occupied molecular orbitals somo will be energetically below the homo level this energetic somohomo inversion shi will represent a disruptive appraoch to stabilize chiral polyradical and to design chiral highspin systems a major breakthrough in material science such innovative union of spin and chirality will give me the opportunity to develop cpoled with 100 of theoretical efficiency and unprecedented near infrared cplightresponsive spinfiltering devices for data processing and storage
hygge star model a new perspective and application

the focal point of this proposal revolves around an interdisciplinary exploration of the hyggestrarmodela comprehensive framework designed to assess selfmanagement motivation within organizational contexts this interdisciplinary inquiry aims to elucidate various facets of the newly conceptualized hyggestrarmodel spanning theoretical underpinnings practical applications and empirical validation the project addresses a salient hr and managerial problem of how to efficiently motivate generation z to engage and perform in the workplace a pivotal component of this endeavor involves the development of a novel measurement instrument namely the universal hygge star questionnaire uhsq tailored to capture the multifaceted dimensions of organizational motivation strong empirical verification will be conducted within the bayesian averaging of classical estimates bace framework in which we can combine some prior knowledge about model distribution and data thus bace serves as an example of a bayesian pooling approach wherein posterior results are averaged over the entire model space furthermore the proposal entails the formation of a crosssectoral research team tasked with devising test protocols and rigorously validating the outcomes derived from the hyggestrarmodel termed as hygge star model a new perspective and application hyggestarmodel this project aspires to offer fresh insights and practical implications for enhancing organizational motivation and effectiveness
a digital twin for electromobility flexibility forecast

as efforts for environmental protection become a major priority electric vehicles evs have started to emerge as one of the main components of sustainable traffic systems in cities worldwide indeed some countries have started to incorporate plans to phaseout conventional vehicles during the next few years with a view to reducing carbon emissions however this shift towards an electrified traffic network involves several challenges that need to be met for evs to become a mainstream feature on the consumers side one of the most common complaints about evs is the lack of appropriate charging infrastructures that would make for seamless daytoday mobility on the side of city officials and stakeholders evs could have a great impact on the power network infrastructure by overloading congested nodes but at the same time evs could be actively used to benefit the power network if vehicletogrid connections became commonplace in order to leverage these opportunities for eflexibility it will first be necessary to model the power requirements and the energy consumption of evs in time and space which are linked to the mobility patterns of people in urban areas as they go about their everyday lives emobtwin is a digitaltwin based on a macroscopic model in which urban ev mobility is combined with an energy model describing vehicles stateofcharge which can run simulations with a fine spacetime granularity emobtwin will also include charging stations along with their exact locations and power characteristics emobtwin will thus become a key tool for making full use of the potential advantages of eflexibility in a wide range of business and industrial contexts including fleet transportation services integration of renewables charging station companies electricity aggregators transmission system operators distribution system operators and electricity markets
quantum violations of thermodynamic uncertainty relations in strongly coupled open quantum systems

recently thermodynamic uncertainty relations turs were discovered in the field of stochastic thermodynamics which fundamentally connect the efficiency power output and reliability of any classical heat engine roughly speaking these turs imply that any efficient heat engine operating at finite power output must suffer from diverging fluctuations in the power output making the engine unreliable surprisingly these turs can be broken in quantum heat engines allowing them to achieve a quantum thermodynamic advantage regarding their output precision with obvious implications for nanoscale applicationsthe proposal research aims to theoretically analyze turs in quantum dot heat engines and establish a clear understanding for which conditions and specific setups turs can be broken unlike previous and most ongoing work this proposal directly attacks the theoretically complicated but experimentally realistic parameter regime of both strong tunnelcoupling and strong coulomb interaction this advance is made possible by a new thermodynamic renormalization group method recently developed by the fellow besides analyzing turs in nonequilibrium steadystates we will also analyze more challenging transient phenomena relevant for the control of device operations and derive generalized quantum turs using a recently discovered nonperturbative fermionic duality mappingthe fellow will be integrated in the group of m leijnse at lund university whose experience in quantum thermodynamics and transport is essential for the action in particular for the planned close collaboration with the experimental groups at the host institute who recently achieved to measure current flucuations of quantum dot heat engines a key step towards the first verification of quantum violations of turs supporting collaborations are set up with the external experts p potts university of basel switzerland and j splettstöer chalmers university sweden
fully recyclable hybrid biocomposite for transport applications

the project aims at the development of a new biobased smart and completely recyclable composite material obtained by fast and low energy consumption outofautoclave process the matrix will be made by a new biobased epoxy resin formulation filled by expanded graphite eg that will have a multiple role in the enhancement of both material and manufacturing process providing smartfunctions a hybrid composite will be developed by the use of hemp and recycled carbon fibers rcfs thus maximizing the environmental benefits with a lifecycle perspective the hybridization will let to exploit the advantages offered by both fibers minimizing the relevant drawbacks the manufacturing process will consist in a low energy version of the prepreg compression moulding pcm aeronautics and automotive field are the main sectors of interest
safeguarding biodiversity and critical ecosystem services across sectors and scales

guardens main mission is to safeguard biodiversity and its contributions to people by bringing them at the forefront of policy and decisionmaking this will be achieved through the development of useroriented decision support applications dsas and leveraging on multistakeholder partnerships msps they will take into account policy and management objectives and priorities across sectors and scales build consensus to tackle data gaps analytical uncertainties or conflicting objectives and assess options to implement adaptive transformative change to do so guarden will make use of a suite of methods and tools using deep learning earth observation and hybrid modelling to augment the amount of standardized and geolocalized biodiversity data buildup a new generation of predictive models of biodiversity and ecosystem status indicators under multiple pressures human and climate and propose a set of complementary ecological indicators likely to be incorporated into local management and policy the guarden approach will be applied at sectoral case studies involving end users and stakeholders through multistakeholder partnerships and addressing critical crosssectoral challenges at the nexus of biodiversity and deployment of energytransport infrastructure agriculture and coastal urban development thus the guarden dsas shall help stakeholders engaged in the challenge to improve their holistic understanding of ecosystem functioning biodiversity loss and its drivers and explore the potential ecological and societal impacts of alternative decisions upon the acquisition of this new knowledge and evidence the dsas will help endusers not only navigate but also reshape the policy landscape to make informed allencompassing decisions through crosssectoral integration