Dragon09/odtu_chatbot huggingface dataset:
multisensor synergies for improved weatherclimateenvironmental products and applications to advance european services supporting green transition

panorama will significantly enhance the quality and accuracy of eo products for supporting datadriven decision making in 3 priority areas of geo climate action disaster risk reduction sustainable development and 7 policy areas of the european green deal climate energy environment and oceans agriculture transport research and innovation the new european bauhaus the next generation of copernicus sentinels and eumetsat mtg and epssg satellite constellation provides a wide range of observations for advanced monitoring of the atmosphere panorama aims to multiply the value of this information by realising multisensor synergies to achieve advanced products along with improved applications on atmospheric composition and nwp eg motionestimation of aerosols clouds fast radiative transfer calculations topdown emission estimations through mlai data assimilation and new physical parameterisations the products and applications will be tested and finetuned in 6 pilot demonstrators to assess the impact of the new eo data on the representation and prediction of extreme weather floods energy and air pollution in its final phase panorama will materialise 3 preoperational integrated applications over the copernicus dias to demonstrate the use of the projects results in seamless climateweather and environmental european services but also to make available the tools to other users and stakeholders eg integrated applications on firesmoke and volcanic ash dispersion for cams and ems and solar energy nowcasting for the nextsense eurogeo service contributions to the c3scmems copernicus services and the destination earth are also foreseen the dissemination communication and exploitation plan will accelerate the adoption of the projects results by the wider community and the commercial sector to ensure impact maximisation
towards nodrift sensors with onchip selfcalibration

sensor drift is a major problem for inertial sensors and limits their usage in autonomous navigation applications inertial sensor data is integrated to find the position and drift leads to error accumulation a common drift suppression approach is temperature calibration but ovenized state of the art sensors still exhibit drift instead of using temperature as a drift indicator i have pursued a nonconventional approach and measured onchip stress that directly correlates with drift the device interacts with its surroundings through the anchors and onchip stress accurately estimates drift i am the leading researcher in the stress compensation field and i have recently demonstrated that mems gyroscope drift could be eliminated with stress compensation my longterm stability results at 2 days of averaging are unrivaled but the calibration algorithm is not practical different from temperature calibration stress calibrating a device is difficult i propose a sensor system that would convert my proof of concept work into a practical 0drift sensor with selfcalibration the proposed system consists of a circular mems sensor with multiple 100 distributed stress sensors and piezoelectric stress transducers a machine learning supported analytical calibration model a custom asic for superior noise and an fpga for system control and selfcalibration if successful the proposed approach would improve the mems gyroscope stability by 100x to the levels of 104 105h enabling errorfree only gravityreferenced inertial navigation unlike gps or camera inertial navigation works under all weather light and location conditions providing a stable reference to navigation algorithms with further miniaturization 0drift sensors could fit into smartphones and reliable indoor navigation would become a reality the compact lowcost sensor could also disrupt the precision inertial market dominated by bulky and expensive fiberoptic and laser sensors
majorana zero mode control and detection platform

the nonabelian state of matter has not been experimentally confirmed and remains an important field of research its detection and manipulation are critical in order to develop a coherent quantum computer in the future the overarching goal of this proposal is to build a working topological qbit based on the braiding of majorana zero modes mzms but there are two main challenges the first is to create a 2d environment where such states can be adiabatically spatially exchanged while the second is to detect the presence and the evolution of such a state to overcome these challenges i will combine two novel techniques that are currently not widely available a the squidontip sot magnetic and thermal microscopy and b a platform to manipulate vortices at the nanoscale that was developed by my research group the research will focus on the mzm which is one of the candidates for a nonabelian state in particular i will consider mzms predicted to be localized at the center of vortices or skyrmionvortex pairs svp the project has three work packages 1 develop a novel platform for vortex and skyrmion manipulation including the integration of a charge detector to detect the vortex charge in trivial vortices 2 investigate different materials and their related heterostructures that could host mzms at the center of vortices or svp these materials include fetese and heterostructures such as strong spinorbit semiconductorsuperconductor ferromagnetssuperconductors 3 combine the results from wp1 and wp2 to detect the presence of mzms this includes gapless edge state and fractional vortices detection using the sot and charge sensing developed in wp1 this ambitious project has the potential to revolutionize quantum computing and quantum materials physics by enabling new experiments it will establish a new field where 2d exchange statistics can be directly controlled and observed
enhancing social wellbeing and economic prosperity by reinforcing the effectiveness of protection and restoration management in mediterranean mpas

the effective main objective is to develop a comprehensive scientific knowledge base and practical guidance combining science technological naturebased solution digitalization and social implication for the application of the ecosystembased management to the protection and restoration management of the eus mediterranean blue natural capitalto ensure the success of this main objective the effective project counts on partners with broad expertise in relevant areas covering all the three pillars of the ebms from applying research stages until companies as follows managerial pillar information pillar and participation pillar and also a naturebased solution in addition this project provides the implementation of the ebms in four pilot areas mar de lempord ebro delta sardinia septentrional cavo greco towards protection and restoration solutions besides taking into account the connectivity between three of them through the existing cetacean migration corridorto achieve the effective main objective the following 5 specific objectives so are identifiedso 1 apply ebms to identify analyze and extend an ecological corridor in the mediterranean sea connecting habitats and biodiversity so 2 apply ebms to analyse and extend the status of 4 mpa in the mediterranean seaso 3 demonstrate 4 naturebased seabed protection and restoration solutions including preserving seabed carbon sequestration capacity in a real environmentso 4 to identify limiting factors gaps and recommendations of existing mpa legislation regarding environmental and anthropogenic pressures setting up links with previous projects so 5 to implement an innovative digital data visualization and aggregation tool in the form of a digital twin for enabling data exploration research participation and citizen science
co2 mineralisation conversion of waste to new building materials

the goal of min co2 is to test the innovation and commercialisation potential of an idea for i increasing sustainability ii decreasing atmospheric co2 and iii producing a valuable low co2 footprint building material from noncombustible solid waste results from our erc research led to the idea can we react waste materials with co2 and water to produce fine grained material of value for new concrete current solutions for ccs are expensive and require extensive infrastructure but if this idea works the technology will generate income our estimates suggest 50 t from the sale of the end product in min co2 we shall test the idea and optimise the system parameters at bench scale then design build and test a laboratory prototype reactor where rate of reaction and formation of a minimum viable product can be achieved in a flowthrough process bringing us from our current trl 2 to trl 4 one patent has been submitted others will follow as appropriate our preliminary market analysis and business case as well as discussions with potential partners waste suppliers a local wastetoenergy plant and a concrete company bode well for writing a proposal for innovation funding at the end of the poc grant larger company stakeholders promise investment when we are able to demonstrate viability in a factory pilot trl 6 our long term goal is a startup that sells co2 traps and knowhow for installation into existing factory chimneys for european and eventually global markets initial discussions with members of the public and the media range from positive to enthusiastic because most of societys fears about ccs are avoided with our approach as our prospective partner from the concrete industry summarised if this works it will be big our small dedicated team is convinced that it will
restoration of the gut microbiome after delivery by caesarean section to prevent asthma

associations between caesarean section cs and childhood asthma may be mediated through microbial changes in 700 children followed prospectively from birth i recently showed that microbial perturbations after delivery by cs explain the delivery modeassociated risk of developing asthma in the first 6 years of life cs was associated with more than a doubled risk of later asthma and allergic sensitization as well as immense compositional changes in the gut microbiota an increased asthma risk was only found in children born by caesarean section if their microbiome did not normalize by age 1 year suggesting that a healthy microbial maturation can alleviate the childs increased asthma riskunder the hypothesis that asthma risk from cs can be avoided by restoring the early gut microbiome the proposed project will identify key environmental dietary and host factors that help restoring a cs perturbed microbiome map the compositional and functional potential of the cs microbial profiles evaluate the role of the virome in the cs associations and perform cocultures of key microbial consortia that may restore a healthy trajectory finally i will perform murine experimental models to validate the findings and perform pilot studies on cs microbiota restoration by fecal microbiota transplantation fmt and fecal virome transplantation fvt in newbornsthis will be a truly translational research project with the potential to go from clinical observations to mechanisms based on bioinformatics and microbiological laboratory work and experimental models and a pilot human trial to infer causal relationships with the perspective of developing a potential future intervention strategyif successful this strategy will be groundbreaking for understanding the microbiomes role in asthma development after cs and in the future potentially lead to novel prevention strategies and targeted efficient microbiota manipulation in children with early microbial perturbations
turku intersectoral excellence scheme

turku intersectoral excellence scheme ties is an innovative fellowship programme that seeks to advance the stateoftheart for postdoctoral research excellence it is based within turku institute for advanced studies tias at the university of turku finland and is supported by turku science park tias has a record for producing worldclass research and developing its fellows for research leadership roles ties offers scientific excellence ties integrates intersectoral perspectives and methods into tiass interdisciplinary institute for advanced studies model on a formal basis this expands the horizons of academic research enabling it to envision original solutions able to address complex issues that affect society as a whole career development ties offers a new range of options for nontenured researchers enabling them to move freely between sectors acquire unique skills and experiences increase their career choices and develop as intersectoral thought leaders innovation ties seeks to build a sustainable infrastructure for innovation by 1 enabling knowledge technology and researchers to circulate freely at regional national and international levels 2 forging deep relations of trust between sectors connecting intellectual excellence with the practical knowhow and infrastructure needed to realise new conceptstias proposes to recruit 4 ties fellows in 2022 and 2023 8 positions in total through an open international competitive meritbased selection process dependent on external peerreview in line with the european charter and code these will be full members of tias with excellent working conditions during their 36month fellowships they will be required to practice international and intersectoral mobility conduct research in a nonacademic sector undertake research secondments with a nonacademic host organisation and develop an individual development programme with mentors and supervisors from inside and outside academia
designing social media recommendation algorithms for societal good

social media platforms are central for civic discourse yet evidence is mounting that they play a causal role in deteriorating social cohesion user behaviour on social media platforms is governed by content recommendation algorithms that maximise engagement leading to unintended consequences such as the promotion of outragethe eus newly enacted digital services act mandates social media platforms to assess their systemic risks for society however the current challenge lies in translating abstract risks to concrete platform design changes that reduce such riskswe will bridge this gap by combining approaches from social science and computer science to incorporate the reduction of risk to civic discourse into content recommendation algorithms of social media platformsto this end we will employ a participationbased approach to develop novel algorithms that consider various aspects of civic discourse such as information quality and diversity and the civility of languagewe will develop open source digital twins of social media platforms to enable experimentation with new algorithms independent of platform companiesto balance the reduction of risk to civic discourse and freedom of expression we will solicit peoples preferences in different scenarios such as a public health crisis and elections and develop balanced algorithmslastly we will develop a scenariobased risk assessment framework to assess algorithms and provide policy recommendations for interventions in content recommendation algorithms the originality of desire stands out in that to date democratic values and fundamental rights played no role in the design of content recommendation algorithms
quantum computers for data centers

aqt is realizing the first european cloudaccessible quantum computer at internationally competing performance levels our two quantum computing setups have been realized within two 19inch rack cabinets each and are each powered by a single wallmounted power plug the hardware is deployed in our data centre and can be installed onpremise at a customer site the project aims to provide cloud access to aqts european quantum computers using a novel aqt cloud platform such that the european quantum ecosystem in particular our quantum software partners and customers can thrive without influence or dependence on currently noneu dominated quantum computing hardware our platform infrastructure is meant to be readily extended toward quantumenabled application services these future application services will allow us to demonstrate and commercially exploit the advantages of quantum computation in finance logistics optimization materials design and chemistry
market technology analysis

adsorbi is a deep tech startup company from gothenburg sweden and was founded after several years of research within materials chemistry adsorbis innovation is a biobased adsorbent material which captures harmful pollutants with high capacity the aim is to replace activated carbon in applications for pollutant removal to lower the high environmental impact and material use of today the goal of the project is to identify which of the many potential application areas to target specifically what should be the first products and who is the ideal first customer of adsorbi the project is divided into four objectives perform a market analysis perform a technical feasibility study perform an ip strategy evaluation and develop a business case around shortlisted attractive application areas
cell rejuvenation therapy for agerelated macular degeneration

agerelated macular degeneration amd is a leading cause for blindness resulting in loss of vision at the center of the visual field the macula due to damage to the retina the disease usually affecting older adults 55 was diagnosed in 2020 in 196 million people worldwide with an estimated economic toll of 343 billion including 255 billion in direct healthcare costs in amd photoreceptors and retinal pigmented epithelium rpe cells which underlie the photoreceptors undergo degeneration the standard care is injections of antivegf medicines such as ranibizumab lucentis aflibercept eylea and brolucizumab beovu to the eye every 13 months these delay disease progress but cannot restore lost vision and have side effects such as bleeding in the eye during an erc starting project the pi has discovered a new method that would allow to not only delay the disease but to also improve rpe cells function as a treatment for amd the proposed approach to rescue rpe cells is rejuvenation by a technique called partial reprogramming our results suggest that the proposed technique is safe and efficient in rejuvenating mouse and human fibroblasts and in improving their function in the current application through in vivo studies we will prepare for implementing our novel approach in our envisioned product isee in isee we will aim to use our discovery of a unique combination of factors that successfully reprogram cells to drive aging rpe cells into rejuvenation and improved function we will calibrate the expression of the reprogramming factors in rpe cells and test rejuvenation and improved function in amd mouse models ipr and partnering with clinician and industry will be developed concomitantly our final product isee is developed based on a pct patent application no 63210030 as a cocktail of molecules of mrna directly applied to the eye to offer the first amd treatment that could restore vision
circhtt in brain development and huntingtons disease elucidating in vivo brain functions of a novel circular rna molecule stemming from the htt locus

i am a neuroscientist specialized on brain development and genetic brain disorders during my phd with dr gaia novarino ist austria i developed a strong expertise in using in vivo mouse models and a large number of different techniques to investigate the underlying cause of intellectual disability and autism my work helped to better understand the pathophysiologic mechanisms driving these complex neurodevelopmental conditions as well as the process of brain development more in general now i aim to expand my research profile to neurodegeneration and the noncoding genome specifically circular rnas circrna as a postdoctoral researcher in the lab of dr biagioli at dep cibio unitn i seek to combine my strong background in functional in vivo studies with her outstanding expertise in huntingtons disease hd research and epigenetics to elucidate a novel regulatory pathway in hd in this proposal i designed a dedicated research and training plan that will significantly expand my scientific portfolio and uncover the in vivo functional roles of circhtt a newly discovered circrna molecule discovered and initially characterized by dr biagiolis lab stemming from the hd locus we will study its mouse orthologue circhtt focusing on expression dynamics and pattern during development and aging and visualize its cellular and subcellular localization in the brain we will analyse its relevance for hd pathology by using hd mouse models and uncover its molecular brain functions by exploiting the innovative and highly specific crisprcas13 knockdown machinery in vivo the results of this project will highlight a novel regulatory network in hd pathophysiology in which circhtt may act as modifier ofor novel biomarker for hd progression or represent a novel molecular drug target this award is vital for me to return from maternity leave and join the biagioli group it will significantly contribute to my career perspectives inside and outside of academia
plugandplay sustainable dyeing solution to help the textile industry reduce energy costs and environmental impact

textile and fashion brands face mounting pressure from national and international policies consumers and institutional investors to transform their practices and decrease greenhouse gas ghg emissions presently textile dyeing methods are both energyintensive resulting in higher ghg emissions and economically burdensome although sustainable dyes can reduce ghg emissions they often come at a higher cost due to expensive materials additional capital investments or the need for high temperatures leading to elevated energy expensesever dye has pioneered an innovative dyeing process with a biosourced pigment effectively detoxifying the textile industry diminishing ghg emissions and significantly reducing energy costs by enabling dyeing at room temperature this breakthrough allows dyeing houses and fashion brands to achieve substantial savings while adhering to the growing demand for emission reduction across the textile value chainever dye has already made considerable headway in the market and intends to carry out laboratory and industrial trials in partnership with several prominent fashion brands