Dragon09/odtu_chatbot huggingface dataset:
harnessing the electric potential of cable bacteria to generate electricity sustainably

cable bacteria are centimetrelong filamentous multicellular bacteria present ubiquitously in freshwater and marine sediments and participate in longdistance electron transfer by coupling the oxidation of sulphide in anoxic sediment to the reduction of oxygen cable bacteria possess an internal electric grid enabling them to transport electrons over centimeterscale distances this project proposes the cultivation of cable bacteria on electrodes to harness their potential to generate electricity further the development of a switchable bioelectrochemical system altering between electrogenesis and electrotrophy is proposed such a device would enable biological power generation and energy storage in a single device and will be tested to power a microprocessor biologically enabling development of biodegradable electronics these experiments would be performed in specialized bioelectrochemical systems by varying the applied potential from positive to negative to induce the switch electrochemical interactions of cable bacteria with electrodes will be monitored by amperometry voltammetry and impedance spectroscopy the cables will be integrated into a power management system consisting of a microprocessor chip a current and voltagemeasuring circuitry and a microcontroller to power the microprocessor with electrons obtained from the sediment finally the physiological possibility of dark oxygen generation by cable bacteria in anaerobic sediments will also be explored that would enable the use of cables as intermediates to convert any aerobic microbe into an electrogen this mechanism will potentially uncover an unknown mode of oxygen production and usher in a completely new understanding of oxygen transport through the oxicanoxic interface the project bridges the applied and fundamental by probing cable bacteria electrophysiology to develop robust applications that will enable sustainable power generation
unified novel deep exploration for critical ore discovery

recent eu initiatives for a circular net zero economy highlight the need for increased raw materials especially critical mineral resources crms traditional exploration methods are limited in scale and depth often missing large crm deposits under thick cover 5001000 m undercover aims to transform deep crm exploration introducing a paradigm shift by extending the mineral systems concept currently underutilised in quantitative exploration to exploration relevant spatial scales undercover integrates key technologies developed by eu academia and companies lowcost lithospherescale surveys eg mt and passive seismic in full 3d target prospective regions regional scale mapping using innovative airborne techniques for identifying exploration targets beyond 1 km depth improved cost efficiency for highresolution deeply penetrating seismic and em methods eg compressive sensing or drones for deposit study and environmental exploitation planning application of ai and joint inversion methods to integrate multiscale multimethod geological geochemical and geochronological data resulting in a 4d multiscale mineral systems model incorporation of esg studies to increase social acceptance and the adoption of our technologies introduction of unfc guidelines integral in our novel exploration strategy as part of the value of informationundercovers strategy envisions publicprivate partnerships collecting precompetitive regional and lithospheric data across europe companies can leverage this data to derisk exploration programs and enhance funding prospects the anticipated impacts are substantial a systematic and reliable approach to deep exploration could double the eu crm potential achieved at a lower cost than conventional methods case studies in finland portugal and namibia demonstrate the strategy by identifying several new deep exploration targets and helping a known deposit to become a sustainable mining project
examining the evolving steering role of ngos on the case law of the interamerican court of human rights

through litigation strategies and thirdparty interventions nongovernmental ngos set the normative agenda of and thereby constantly reshape the interamerican court of human rights iacthr yet most studies on the evolving jurisprudence of the interamerican human rights system ias relating to environmental matters primarily centre on the interpretative innovations made by its judiciaryngosteeriacthr develops and applies an analytically and empirically grounded framework to examine the influence of ngos agendasetting power on the iacthrs case law in which environmental protection serves the interests of human rights whilst generating uptodata knowledge on the role of ngos within the ias this projects differs from the stateoftheart by illustrating to what extent the evolving human rights and environment agenda of ngos is behind the evolving iacthrs jurisprudence on the subject to this end it will combine doctrinal and content analysis of selected contentious cases involving indigenous groups environmental defenders and the right to a healthy environment and the advisory opinion no 23 on human rights and the environmentas children are now getting involved in litigation before the ias soleil v haiti ngosteeriacthr will provide a better understanding of how and to what extent the human rights and environmental agenda can be incorporated throughout the written and oral phases of contentious cases besides considering that the iacthr may employ its advisory proceedings to influence state behaviour and address questions that are likely to arise before its contentious jurisdiction it will offer clear insights into the role implicitly played by ngos in shaping the normative countours of the advisory opinion no 23 and state conduct alike
divergence times evolution and anatomy deciphered in early sharks

the ancient elasmobranchs sharks rays have the potential to provide great insight into evolutionary processes over large timescales but this potential is limited by a poor understanding of the relationships between living and extinct groups and the timing of major divergence events in this project i will address these knowledge gaps by combining new 3d tomographic data on key mesozoic elasmobranch body fossils with genomic and anatomical data from their living relatives i will then use this and a dataset of 3d elasmobranch lower jaws to investigate the dynamics of elasmobranch macroevolution using the rate and mode of lower jaw shape evolution as a case study in doing so i will build on my existing background in palaeobiology and 3d methods by learning new skills in genomicsbased phylogenetics and 3d geometric morphometrics while developing my skills as a supervisor communicator and leader these new skills along with the scientific groundwork laid by this project will give me the tools to pursue an independent programme of research in the longer term investigating the early evolution of elasmobranchs by combining data from animals both living and extinct
autobiographical memory time and environmental navigation unveiling the cognitive map of our past through an integrated neuropsychological perspective

episodic autobiographical memory refers to the ability to recollect and reexperience events of our own life that occurred at a particular time and place it allows for the development and maintenance of our unique personal identity and selfawareness namely autonoetic consciousness an integrated and comprehensive model of how and where episodic autobiographical memories are stored in the human brain is still lacking the core hypothesis of atena is that previous experiences are spatially organized into a cognitive map and that temporal coding indexes the content of such a map also a dynamic remapping should occur in the brain as time passes after the event recent theoretical and methodological advances in cognitive neuroscience make the study of episodic autobiographical memory timely atena will integrate cognitive neuropsychological and neuroimaging approaches to demonstrate that retrieving autobiographical memories crucially relies on spatial and temporal processing in brief advanced informationbased approaches to neuroimaging ie representation similarity analysis and decoding will be adopted to directly test the neural representation underlying episodic autobiographical memory and its possible dynamic remapping across time a lifespan developmental study will be designed to test the ontogeny of place and time contribution to episodic autobiographical memory finally the contribution of the alterations in time and place coding in different developmental and acquired neuropsychological conditions characterized by a deficit in episodic autobiographical memory will be tested besides a novel integrated neuroscientific account of episodic autobiographical memory and its development across the lifespan atena will open new areas of investigation in the field of the human mind and its complexity and will inspire new approaches for neuropsychological rehabilitation of memory deficits
the identification of the reactive pore space in soils

ensuring the quality of our soils is essential for a sustainable world testing the soil quality traditionally occurs by soil sampling sieving and extraction thereby disturbing the soils hierarchical pore size structure soil sieving and extraction disrupts the macroaggregates and overestimates the accessible reactive surfaces of soil plant roots are exposed to only a fraction of these soil reactive surfaces hence traditional soil tests for bioavailability underscore the physical nonequilibrium of nutrients and contaminants in soil exposoil aims to identify the reactive pore space to which roots are exposed in undisturbed soil the research objectives are to quantify the effects of soil structure and mobile colloids on bioavailability of nutrients and contaminants and to develop methods to understand and diagnose these effects we speculate that these effects create local heterogeneities that are most important in soils with stronger aggregate structure for contaminants or nutrients that are relatively immobile and less aged in soil and for elements strongly associated to mobile colloids experimental studies will be set up to test these hypotheses in soils with surface amended trace metal contaminants fertilisers or lime using isotopes to trace local provenances and using novel visualisation tools novel reactive membranes acting as zero sinks for solutes and colloids will be developed to mimic plant roots and to make 2d images of the locally available elements that development is of high risk but high gain because no other method has yet assayed diffusive fluxes of solutes let alone of colloids in unsaturated and undisturbed soils the new method will disclose the enigmatic roles of soil physical factors and colloids on bioavailability this knowledge will advance the practical use of soil chemistry in environmental applications eg to improve existing soil testing assays and to facilitate the development of novel more efficient fertilisers
in vitro reconstitution of the initiation of mitophagosome formation

mitophagy is a tightly controlled process in which dysfunctional mitochondria are isolated and selectively degraded by autophagy many cell types critically rely on this pathway and mitophagy is therefore essential to life for instance egg fertilization or red blood cell development would not be possible without mitophagy the importance of mitophagy is further underscored by its many links to human disease most evident by mutations in the protein kinase pink1 and the e3 ubiquitin ligase parkin causing autosomal recessive parkinsons disease while most factors required for mitophagy are known a major outstanding question is how do the different factors come together to produce a mitophagosome as the process comprises many different factors each with a unique role this is a challenging scientific question to address the goal of this project is to gain insight into this process using biochemical reconstitution to elucidate how more than 15 different factors work together to initiate the formation of a mitophagosome a unique aspect about our approach is that it not only allows to elucidate how mitophagosome formation is initiated it could also reveal additional layers of finetuning for instance also explaining how mitophagy is prevented from being initiated too early this project may therefore lead to a major step forward establishing a coherent framework of how mitophagosome formation is organized moreover it could lead to new avenues for treating devastating neurodegenerative diseases like parkinson
full qualification testing and commercial deployment of a unique onchip memory technology offering the highestdensity embedded memory in a standard cmos process

the memory bottleneck has become a major concern in modern systemsonachip and hence the size of onchip embedded memory continues to increase already reaching up to 75 of the total soc real estate however the industry standard sram technology is very areainefficient and has been facing major scaling difficulties in modern process technologies beyond 10nmraaams gaincell random access memory gcram technology is a unique onchip memory solution that only requires 23 transistors to store a bit of data as opposed to 68 transistors needed for the existing srambased highestdensity memory technology the solution is area efficient costeffective and can be manufactured using the standard cmos process having successfully tested the technology in various nodes ranging from 180nm16nm raaam currently aims to develop fabricate and characterize the proposed memory technology for nodes 5nm and to fully qualify it for production according to industry standards
operator algebras that one can see

graph calgebras are analytical objects blessed with a tangible structure and classification theory derived from their combinatorial origins through the analysis of directed graphs including higherrank graphs or quantum graphs one can visualize and explore them in intuitive ways lacking elsewhere they serve as strikingly efficient models for key open problems in noncommutative geometry and topology as well as in cdynamical systems they also provide a focal point for the muchneeded extension of the celebrated elliott classification program to nonsimple calgebras the main objective of the project is to achieve a critical mass for a successful attack on these problems by combining the weight of strong research groups inside and outside the eu using graph algebras as a unifying vehicle for hitherto unconnected areas of mathematics the synergy of these new and innovative connections should allow us to develop and apply brand new methods unavailable otherwise furthermore researchers using graph calgebras for applications in adjacent fields are likely to provide groundbreaking insights making impact way beyond graph algebras themselves in particular we expect to develop an interdisciplinary dimension involving quantum computingwe aim to achieve our objective through networking and transfer of knowledge between twenty six partners from the eu and north america participating in the network there are worldwide leading scientific centers among about seventy researchers involved in the project there are famous experts and extremely efficient mentors of young researchers combining them with student members of the network yields a top humanresource infrastructure an important objective is to take advantage of that potential by creating new career opportunities another tremendous asset of the network is a unique opportunity it gives to tie new and lasting connections for successful transcontinental scientific collaboration
the sensory ecology of water a multisensory anthropological study of outdoor swimming in the arctic

my project aims to rethink humanmorethanhuman interconnectedness by examining entangled relationships between arctic waters the senses and place as a community of practice outdoor swimming in norway provides a unique lens through which to examine a sharing in the sensible groundedin holistic planetary wellbeing following the global covid19 pandemic and wellbeing crisis practitioners tourism agencies and popular media outlets have lauded outdoor swimming as a therapeutic cure for human health wellbeing and for a perceived lack of connection to nature examining relational notions of wellbeing in bluespaces and stewardship of nature in immersive experiences outdoors generates novel insights into sensory knowledges and the cultural values of waters in rapidly changing arctic climates in doing so this project expands the methodological affordances of anthropology by conjoining participant sensation in qualitative sensory ethnography with discourse analysis and close readings in the pursuit of three objectives 1 identify historical and contemporary meanings of norwegian outdoor recreation friluftsliv and wellbeing as presented in and related to outdoor swimming 2 trace how interactions with water and morethanhuman others shape the swimming sensorium and 3 uncover the potential for sensory ecologies to inform planetary conviviality in water management and competency policies sensory approaches used in this project may reveal power relations local forms of water management and wellbeing resilience the negotiated use of space and formation of placeattachment this examination of how the perceived therapeutic healing practice of outdoor swimming can be mobilized to include material and ecological strategies for advancing water security and ensuring quality water sources for all europeans
final act of the autophagy symphony wholeorganism orchestration of autophagy termination

when an organism experiences physiological stresses such as nutrient starvation it activates several mechanisms to promote its survival one of these mechanisms is autophagy which is a catabolic pathway conserved from yeast to man that functions as a recycling system during normal physiology and which helps provide nutrients to sustain essential cellular processes during starvation although autophagy is an intensively studied process that plays a major role both in normal development and in a wide variety of diseases several important aspects of autophagy remain to be elucidated for instance whereas the vast majority of studies have focused on how cells regulate the activation of autophagy it remains largely unknown how cells and organisms shut off autophagy in response to returning nutrient availability the limited knowledge of autophagy termination is partly due to a lack of available tools and appropriate methods addressing these challenges will not only provide important insight in this fundamental aspect of the autophagic process but may potentially also identify new targets for development of drugs to manipulate this phase of autophagy in finalphagy i will develop new genetic and computational tools to quantify and manipulate the temporal dynamics of autophagy in an entire organism i will unravel key mechanism of autophagy termination in individual cells within a tissue and dissect how this connects to systemic signaling and behavioral changes this will generate a comprehensive toolbox for time and spaceresolved manipulation and quantification of autophagy levels produce a wholeorganism map of autophagy responses at the tissuelevel and conceptualize our understanding of the dynamics of autophagy regulation in an entire organism during changing nutrient levels
creating leverage to enhance biodiversity outcomes of global biomass trade

clever identifies new leverage points for sustainable transformation informed by a novel holistic approach to quantify biodiversity and other impacts of trade in major raw and processed nonfood biomass value chains in line with pillars 3 4 of the eu biodiversity strategy 2030 we address all outcomes of this topic by adopting perspectives at the system and value chain levels at the system level we improve our understanding of leakage effects in the nonfood biomass trade system informed by quasiexperimental evaluation techniques quantitative scenario modelling and policy case studies at the value chain level clever engages with key stakeholders ie producers traders retailers civil society and policy makers in ri codesign to identify leverage points for transformative change at corporate and institutional levels value chain analyses will produce ecological footprints from advanced life cycle analyses and enhance our understanding of actorspecific behavior focusing on trade in soy timber wood pulp and fishmealoil between europe south america and central africa further clever products and tools to influence decisionmaking at the right level include 1 improved indicators of biodiversity loss to inform business and policy 2 enhanced features for the global modelling platform globiom to quantify trademediated leakage and sdg interdependencies in biomass value chains and 3 an innovation action pool to support public and private decisionmakers in choosing governance instruments that effectively enhance biodiversity and promote climate change mitigation and adaptation building on prior and ongoing engagement of its members at the sciencepolicy interface and through partnerships with other projects under the destination on biodiversity and ecosystem services the consortium will leverage clever knowledge and tools to strengthen ipbes and ipcc and enhance scienceindustry cooperation for sustainable bioeconomic transformation
complex lipid membranes for science and technology

climbcomplex lipid membranes for science and technology is a doctoral network of leading european lipidresearch laboratories with highly complementary research expertise and training capabilities which will allow participating phd students to develop a wide range of research and transferable skills attractive to employers in both academic and industrial sectorsthe research themes focus on the hypothesis that comprehensive understanding of the role of compositional complexity on yet to be explored structural properties and membranedriven interactions is key to developing complex lipidbased nanomaterials that mimic the cellular environment and function as highperformance sustainable materialsa central aspect of the climb programme is the development and physicochemical characterization of structure and stability of aggregates formed by novel lipid mixtures including natural extracts and novel protective polymerpeptoidbased coatings scientific results will be made available to nonacademic partners to assess its possible translation into applications in the fields of mrna delivery biosensor development and green formulations areas in line with some of the grand challenges identified by euthese objectives will be achieved by combining advanced and complementary experimental approaches from chemistry physics biology and computational sciences through close collaboration with a network of both small and large industrial partners the trainees will receive direct handson experience and will gain insights into how lipidbased materials are used in innovative applicationsin summary climb aims to advance the current knowledge on the interplay between structure functions interaction and compositional complexity in lipid membrane the generated results will contribute to important knowledge transfer between academia and the companies involved promoting and increasing the success rate for innovations of grand societal challenges