Dragon09/odtu_chatbot huggingface dataset:
empowering citizens in collaborative environmental compliance assurance via monitoring reporting and action

more4nature aims to trigger transformative change in conservation efforts regarding zero pollution biodiversity protection and deforestation prevention by including citizens and communities as key actors in collaborative environmental compliance assurance ecaa key element in reversing the trend in environmental degradation is a change in environmental compliance assurance interventions citizen science initiatives csis present innovative ways of joint data and knowledge production and of empowering citizens in sustainable natural resource management however barriers to the uptake of citizen generated data cgd and citizen actions in eca have not been effectively tackledmore4nature will use a sociotechnical approach to address these challenges and deepen the role of citizens and communities in eca by i strengthening the capacity of existing csis to provide relevant and valid data and understanding the importance of eca ii fostering and supporting collaboration and partnerships among citizen science initiatives and authorities to cover data gaps and shape policy monitoring frameworks iii developing and testing tools to validate data obtained from csis thus contributing to the integration of such data sources in environmental governance and in european open science cloud iv making cgd available as a node in the green deal data space and v channeling the urgency for concrete and immediate action of many citizens and communities by creating synergies between citizen science initiatives and livinglabs for eu missions partnerships and other initiatives such as fab labs which share the values of sustainability transitions and which can help codesign actions as part of green and digital transformations more4nature will ensure uptake and impact beyond the project duration by engaging 162 existing csis and 98 authorities and national agencies in 40 cases in europe latin america asia and africa as well as selected livinglabs and fab labs in europe
egnss enabled standardized european road condition monitoring and distribution

road wear stands as a pervasive challenge and a significant financial burden in infrastructure upkeep detecting and mapping road wear early and in detail can alleviate these costs and simultaneously extend the lifespan of road surfaces the project team successfully finalised the egnssproject esrium trl 6 in november 2023 identified necessary technological and standardisation steps for entering into the market and targets this tender as an optimal windowofopportunity for doing so the overall objective of esercomd is to facilitate standardization efforts through the implementation of a demonstrable service trl 8 which fosters greener and smarter road usage optimizes road maintenance and increases road safety in doing so the automation of the complete chain from road condition monitoring to smart decision making will be demonstratedmoreover the project seeks to establish contact and create liaison with key standardization bodies and expand the utilization of egnss in the road and automotive industry the goals emphasize the importance of aligning developments with international industryaccepted certification and standardization schemes through comprehensive testing and validation in reallife environments esercomd aims to provide proof of concept demonstrators for standardization concepts ensuring the sustainable impact and widespread acceptance of its outcomes the projects commitment to transparency user acceptance assessment and fostering sustainable impact underscores its excellence in addressing current challenges and pushing the boundaries of the state of the art in road wear assessment and maintenance
sugarcoating matters deciphering the effects of aberrant receptor nglycosylation on oncogenesis and drug resistance in acute myeloid leukemia

during my postdoctoral studies i have shown that sugarcoating of proteins nglycosylation specifically is essential for the development and a potential therapeutic target in the blood cancer myeloproliferative neoplasms here i show that differential expression of three enzymes that are key to protein sugar coating are strong novel prognostic factors in the blood cancer acute myeloid leukemia aml specifically these enzymes remove or add glucose molecules of the nglycan sugar tree removal of the outer glucoses is essential for retaining nglycoproteins within the endoplasmic reticulum er and unprocessed nglycans contain a high number of mannose sugars i hypothesize that unprocessed nglycoproteins such as growth receptors and drug removal pumps escape the er and are expressed on the cell surface at a higher level due to abnormal expression of genes implicated in sugar coating alg10b mogs and prkcsh this in turn contributes to aml development and poor outcome to proof my hypothesis i will decipher the role of key enzymes in nglycan glucose addition and removal to myeloid oncogenesis aim 1a and drug resistance aim 1b using colony forming unit assays and cell lines that express alg10b or lack mogsprkcsh crisprcas9 knockout additionally i will assess mannose abundance and targetability on primary aml versus healthy control bone marrow samples aim 2a and map nglycan structures using recently developed highthroughput mass spectrometry and analyses techniques aim 2b i will correlate structural nglycan profiles with expression of nglycan processing enzymes assessed through rnasequencing to create a full picture of nglycosylation aberrancies in aml this study will decipher the molecular mechanisms underlying aberrant nglycosylation in aml and provide anchor points for novel aml therapies this is important because the current 5year overall survival rate of aml is only 30 so therapy improvements are highly warranted
propagation of cellular memory through dormancy

decades of work established the importance of dormant cells in reproduction and regeneration however a central unsolved question is how the cell propagates transcriptional memory and cellular identity through dormancy current approaches tend to characterize dormancy as a binary onoff switch in contrast a highly coordinated and precisely timed set of events are needed to successfully transition cells into dormancy to maintain dormancy and to exit it in dorcode i will leverage the latest gene editing and genome profiling tools on an inducible and reversible embryonic dormancy model that i spearheaded bulutkarslioglu et al 2016 van der weijden et al 2022 to discover the genomic basis of dormancy my mission is to reveal the temporal regulatory code of dormancy dorcode without which cellular identity cannot be propagated through timerecent work by us and others has started to reveal the epigenomic landscape of dormancy a highly repressed state with elevated dna and histone methylation and decreased transcriptional output cellular strategies to counteract this overall repressive state at regulatory sites at the correct times are key for the retention of developmental potential here i will identify dna and histone demethylation strategies to propagate transcriptional memory at key regulatory elements objectives 12 and connect locusspecific regulation objectives 12 to genome macroorganization objective 3 by building direct links between anabolic growth and genome regulation i will demonstrate how timely gene reactivation is ensured to enable exit from dormancy the conceptual leap and mechanistic insights resulting from dorcode will 1 enhance our knowledge of embryonic dormancy and lay the foundation for better in vitro embryo preservation 2 bring a fresh perspective to related systems such as regeneration longevity and cancer dormancy and 3 fuel the research in my lab for decades to come
magheat understanding energy deposition in the solar chromosphere

the mechanisms that heat the solar chromosphere and corona and that drive the solar dynamo arguably remain some of the foremost questions in solar and stellar physics here we focus on the question of how energy is transported and released in the solar chromosphere during the past 20 years numerical simulations of the chromosphere have been used with increasing degree of sophistication to validate various proposed heating mechanisms these studies have gradually come to recognise that the mechanisms that are likely dominant may be different in different parts of chromospheric fine structures to make progress we therefore need constraints from highly resolved observational datarecently i implemented an inversion code that allows estimates of the overall chromospheric heating from spatially and spectrally resolved observational maps our results have unveiled very finely structured heating distributions with much larger amplitudes than the hitherto assumed canonical values but a limitation is that this implementation cannot directly discriminate between the different heating mechanisms that have been proposedthe goal of magheat is to identify what mechanisms are heating the chromosphere characterize the energy flux that is being released into the chromosphere and separate the contribution from each mechanism in active regions and flares this goal is achievable with the combination of the proposed development of novel nonlte inversion methods new hybrid rmhdparticle simulations and the availability of datasets with unprecedented high spatial resolution large fieldofview and high sn ratio from dkist the sunrise iii mission nasas iris satellite and updated instrumentation at the swedish 1m solar telescope we will use observational data from these facilities to reconstruct new 3d empirical models of the photosphere and chromosphere which will allow us to identify the mechanisms that are responsible for the energy deposition
indium phosphidebased advanced monolithically integrated photonic buildingblocks at near and midinfrared wavelengths

innovative groundbreaking technologies such as nanosatellitebased space navigation and autonomous navigation are currently hindered by the lack of compact efficient sensing devices the adoption of photonic integrated circuits pics for these applications has been restrained by the difficulty of integrating complete photonic sensors without optical interface within the same chipthe aim of inphomir project is to provide a competitive and independent european supply chain of monolithic pic buildingblocks operating at near and midinfrared wavelengths by proposing the indium phosphide platform as a valid solution for a technological scaleup the scientific activities will involve the validation of pics with new ultralow loss waveguides and new midinfrared active devices and the first demonstration of advanced building blocks such as extremelyhigh quality factor resonators at telecom exploring optical loss compensation and slow light effect in photonic crystals hertzlevel narrowlinewidth quantum cascade lasers and ultralowpower sensitive heterodyne detectors at midinfrared wavelengths these advanced components will be employed to realise for the first time an integrated optical gyroscope and a dualband midinfrared fmcw lidar these two novel sensors will be put together onto a multichip module board to validate a novel multisensorial unit with unique ranging and inertial sensing capabilities to be exploited for aerospace missions of lowearthorbit nanosatellites and selfdriving drones thus a consortium has been established constituted by academic and industrial partners to provide the necessary expertise and synergy in frontend design microfabrication and backend packaging test sensor fusion research activities as well as specifications definition and technological validationexploitation of the developed usecases the proposed multisensor module will boost miniaturised and advanced technologies in leading eu industries
ramon llullaira postdoctoral programme postdoctoral programme

the ramon llullaira postdoctoral programme ramon llull is an international postdoctoral programme offering 33 threeyear fellowships to train researchers in the outstanding rd institutions in artificial intelligence ai in catalonia to become competent scientific leaders in different scientific disciplines within ai by promoting challenging interdisciplinary rd projectsthe programme is led by the computer vision centre cvccerca holder of the current artificial intelligence research alliance aira the axis for knowledge generation within the current catalan strategy for ai cataloniaai cvccerca is acting as beneficiary together with aira partner institutions iiiacsic bsc ideaiupc iriicsicupc and 8 further outstanding research institutions in artificial intelligence ai uab upf udg url urv eurecat i2cat ijccerca 5 universities 2 technology centres and 1 clinical research institution which will participate as implementing partners for the recruitment hosting training of the er fellowsthe programme is created with the explicit encouragement and direct support from the catalan government committing to support the activities of the programme through aira initiativeramon llull programme will contribute to boost career perspectives of researchers with outstanding academic quality from a threedimensional perspective excellent human centred ai research leadership and interdisciplinary research with other top rd intensive institutions and companiesthe programme will provide a new dimension for the catalan rd ecosystem in ai through highly interdisciplinary and intersectoral fundamental research while fulfilling all the principles of open science and maintaining the highest research quality standards it is aimed to optimise the capacity of the catalan ai ecosystem by recruiting hosting and training researchers in ai ri institutions in catalonia with the ambition to become competent scientific leaders in different ai disciplines
integrated sensing energy and communication for 6g networks

the idea of joint communication and sensing jcs capabilities is a revolutionary and innovative solution a single system has the potential to offer significant advances in various fields such as smart transportation smart cities smart homes healthcare security and environmental monitoring isee6g extends beyond jcs and propose a joint communication computation sensing and power transfer jccsp unified radio platform which includes all support elements of the proposed solutions in future 6g networks by integrating exploiting and supporting 6g key enabling technologies isee6g offers a jccsporiented novel intelligent reconfigurable surfaces ris and agile beamforming array solutions b jccspoptimized physical layer design including waveform design frame structure design channel modeling precodingbeamforming with respect to open radio access network oran architectural paradigm c jccspenabled crosslayer schemes design under new capabilities in terms of serviceoriented network architecture and d jccspimplemented systemlevel solutions for providing new functionalities towards a cellfree 6g network the isee6g proofofconcept poc focuses in jccsp use cases in aerial corridors where uavs with various roles providing different services coexist and coordinate with each other in imecs testbed static distributed rus and vehicular ues are additionally included for an emergency response incident the uavs monitor the area estimate and report accurate positioning and provide situational awareness through integrated sensing in oros testbed 5g waveforms based jccsp exploit the kpi collection capabilities of it the operation of the testbed will be extended at an outdoor venue where uavs and iot devices will be deployed to test the wireless power transfer wpt capabilities edge computational power is used for public protection and desaster relief ppdr monitoring and jccspasaservice implementation
combatting diet related noncommunicable disease through enhanced surveillance

our current understanding of the relationship between diet and the development of noncommunicable disease ncd is limited by a number of factors these include a lack of understanding of dietary mechanisms that drive ncd inaccurate tools to collect dietary information a nascent understanding of the role of personalised nutrition and the lack of data in vulnerable groups where ncds are often overrepresented the overarching aim of codiet is to develop a series of tools through eight work packages which will address the current gaps in our knowledge and lead to the development of a tool that will assess dietaryinduced ncd risk we will achieve this through the six objectives which will answer the challenges of the work programme1 development of aidriven literature searching tools bring clear understanding of large global literature in the field of physiological and metabolic links between diet and ncd2 enhance the understanding of ncd risk factors we will bring a series of beyond the state of the technics to gain mechanistic insight 3 understanding of the importance individual variation in response to diet to risk of ncd this will give insight into the targeting of dietary ncd advice4 develop an enhanced method of dietary assessment using machine learning technologies solving a fundamental problem in nutrition of lack of an accurate dietary tool5 develop an enhance dietncd monitoring tool enabling change in ncd in response to diet to be monitored at the population level6 develop a dynamic interface between diet and ncd risk factor monitoring and policy ensuring codiet is applicable at a population levelthe investigation of these objectives and the answers they provide will open a pathway to enhancing the uptake of ncd protective diet at a population level
bioarchaeology of orchards and sustainable terroir in the arid near east trends in ecology and evolution

engaging with the myriad challenges linked to global warming and the unchecked expansion of drylands the project seeks to develop models for implementing past agricultural knowhow in modern socioeconomic contexts our novel methodology fuses cuttingedge interdisciplinary scientific approaches from the humanities and natural sciences with an inclusive citizen science framework to examine the ecological history and cultivar diversity of relic heritage horticulture in four distinct arid regions in southern israel focusing on the bioarchaeology of trees we will define the historical biological and environmental principles of dryland heritage horticulture systems and create a method for the exploration analysis and ultimate dissemination of the crucial data they contain when combined this exceptional compendium of perspectivescoupling broad sociogeographical scientific viewpoints with more precise biogenetic archaeological and natural science analyticscan expand our understanding of the factors that drove the sustainability of heritage horticulture in marginal areas the outcome of our studyan archaeologically informed grasp of ancient agrarian resiliencecan transform the field of environmental history and impact presentandfuture agricultural dynamics indeed viewing trees as a singular analytical unit is unprecedented as is our interdisciplinary survey of both the dormant and living artifacts contained within these archaeological contexts hence deep knowledge of how bygone farmers related to the landscape and managed their limited resources particularly the terrain soil and water holds vital implications for climate change adaptation and currentday food security moreover the unique history of dryland farming and its remarkable development in marginal regions can inspire landscape policy management initiatives and community engagement programs that promote cultural heritage restoration and landscape reclamation
pioneering sustainable recovery in steelmaking hydrogenbased technology for byproduct management

the dust2value project aims to transform the steelmaking residue recycling process by introducing an innovative hydrogen reduction technology that efficiently recovers valuable metals such as zinc and iron from steelmaking residue streams this environmentallyfriendly technology supports the circular economy reduces greenhouse gas emissions and contributes to a sustainable future for the steel industrythe dust2value process utilizes green hydrogen to reduce zinc oxide and iron oxide present in the residue converting them into gaseous zinc that evaporates reoxidizes with water vapor to finedispersed zno particles which leave the furnace via the offgas system and are recovered in bag house filters additionally a secondary dri is produced the novel design of the dust2value process recovers heat and hydrogen generated during the reoxidation of gaseous zinc to finedispersed zno particles optimizing its energy efficiency the project will design construct and optimize a prototype rotary kiln that enables optimized heat transfer and gassolid interactions ensuring effective metal recoverya key aspect of the dust2value project is the integration of digitalization and machine learning techniques for process modelling and optimization the project will leverage machine learning algorithms trained on kinetic data from thermogravimetry to create an accurate and comprehensive process model this model will be used for the dimensioning of the prototype and will be further developed into a digital twin providing a realtime representation of the physical process the digital twin will enable continuous monitoring analysis and optimization of the process ensuring optimal performance and facilitating the rapid implementation of improvements this advanced approach to process modelling will significantly enhance the dust2value process optimisation driving innovation in the field of steelmaking residue recycling
rethinking psychological acculturation from explicit to implicit cultural affiliations

the topic of psychological acculturation ie changes in psychological and behavioural patterns due to sustained contact with another culture is both timely and relevant 29 pct of european citizens are ethnic minorities and integration is omnipresent in debates on inequality and societal tension yet our scientific understanding of this process is still poor the current approach to acculturation narrowly focuses on ethnic minorities explicit willingness to not be part of a culture as reflected in their cultural attitudes and identities psychacc pushes boundaries by proving the existence of acculturation in selfconstrual cognition and motivation building on the notion that peoples ways of being thinking and drivers for action signal cultural affiliations implicitly from there psychacc elucidates the complex interplay between acculturative changes in explicit and implicit cultural affiliations and identifies people with distinct acculturative profiles which are then used to predict wellbeing and educational outcomes finally psychacc opens the black box of acculturation by showing that these changes are driven by specific microprocesses in majorityminority interactions like establishing common ground it builds its evidence through four studies a crosscultural a 2 year representative longitudinal an experimental and an observational one all focusing on ethnic minority and majority youth 1418y in belgium together the envisioned results rethink psychological acculturation no longer as minorities willingness visvis cultures but as a multifaceted process of change that emerges from meaningful intercultural interactions in sum psychacc offers a novel theory a beyondstateoftheart methodological toolbox and pivotal evidence to trigger a paradigm shift in acculturation research it also inspires entirely new research lines in other social sciences and policy makers to look beyond outer signs of integration