Dragon09/odtu_chatbot huggingface dataset:
fever global histories of a disease 17501840

fever is one of the most basic and pervasive of human experiences even before the current covid19 pandemic took this to new extremes fever and the attendant sensations of burning up or having ones temperature taken had long been familiar to men women and indeed children while fever is a universal feature of humans material existence however its relevance and meaning differed from one historical context to another the proposed erc project studies fever globally particularly in societies within or tied to the atlantic world in the century spanning from the 1750s to the 1840s a time when fever was not only considered the most common ailment that afflicted mankind but also its most fatal one more persons died of fever than of all other ailments combined as contemporaries saw it given that fever was a threatening ubiquitous presence for men and women around 1800 we know surprisingly little about it as one medical historian recently put it fever has been the invisible elephant in the china shop of the medical past premised upon archival research in countries across the world the various subprojects expose and explain the unusual prevalence of fever in the periods medical record its persistent association with particular insalubrious environments rather than contagion the unceasing relevance of vernacular folk and indigenous fever remedies in many atlantic societies and fevers resonance and relation with similar disease concepts in other noneuropean empires the project also breaks new ground methodologically in its global new materialist and interdisciplinary approach its dialogue with the medical sciences history and philosophy of science and environmental studies it poses questions fundamental to our understanding of both the past and the present about the rise and fall of diseases the credibility of medical knowledge and how cultural and historical contexts affect suffering and physiology and vice versa
adaptive potential for changes in environmental conditions in exploited fish species

global change is threatening life at the seas by changing the physical chemical and biological conditions of the environment thus marine species will need to adapt to the new environmental conditions to thrive this adaptation depends on the genetic variation within species as it is the raw material on which natural selection works because environmental conditions at the sea are heterogeneous and most marine species are distributed across these diverse marine environments it is likely that the genetic variation making possible the adaptation to changes in the environment is currently present within populations thus the genetic flow among populations or environments can be one of the most important factors enabling adaptation to future environmental conditions in fish however harvesting fish populations is likely eroding their capacity to adapt to changes in the environment where they live thus the goal of this study is to quantify the adaptive potential and likelihood of adaptation to environmental change in exploited fish populations contributing with clear transferable knowledge to fisheries management strategies towards longterm sustainability to do this we will use neutral and functional genetic variation data of two fish species from different environments presenting different degrees of exploitation potentially adaptive genetic variation will be revealed by looking for signals of both adaptive and balancing selection among environments then we will quantify the amount of potentially adaptive genetic variation and the effect of harvesting on it finally we will investigate the strength of selection to get a likelihood of adaptation to future environmental change overall the expected results of this study will set up theoretical and methodological frameworks for the evaluation of the current levels of adaptive potential for future environmental change in exploited fisheries
enslaved persons in the making of societies and cultures in western eurasia and africa 1000 bce 300 ce

slavegents is an ambitious project focused on slave agency it aims to explore how enslaved persons in antiquity actively shaped the societies they lived in it will examine the multiple identities of enslaved persons the communities and networks that they created or participated in and how slave agency brought about major political social economic and cultural changes in the ancient world by exploring the various forms of slave agency slavegents will offer a radically new perspective on antiquity from the point of view of history from below the project moves beyond the usual focus on slavery in classical greece and roman italy to offer a comprehensive examination of the history of enslaved persons across western eurasia and north africa between 1000 bce and 300 ce slavegents is the first project to examine together all ancient slaveries from mesopotamia to the atlantic and include sources in the full range of ancient languages assyrian babylonian hebrew aramaic phoenician egyptian greek latin and the relevant archaeological data the research team composed of the pi eight senior researchers seven postdoctoral researchers and three phd candidates will construct a largescale digital prosopography of all attested ancient slaves which will include all relevant sources in the original and in english translation the linked open data created by the digital prosopography will enable new forms of quantitative and qualitative research and will make a significant contribution to digital humanities the monograph and the two collective volumes of the project will offer an important step towards rewriting the history of antiquity with slaves at its centre in addition the project will deliver fifteen articles three phd dissertations three workshops one international conference and a website
doing the impossible adaptive behaviour in migratory birds to overcome physiological and environmental constraints

advances in tracking technology during the last decade have shown that migratory birds have the capacity to fly longer and faster than we previously thought was possible yet we do not know how birds perform these seemingly impossible travels as it previously only was possible to record spatiotemporal patterns the overall aim of this project is to reveal constraints and the behavioural and physiological adaptations that has evolved to overcome them thus making the extreme performances of migratory birds possible this goal will be met by using novel tracking devices multisensor data loggers that in addition to spatiotemporal patterns also record behaviour including flight altitudes temperature and detailed timing of flights and stopovers during the entire migration cycle the few multisensor tracking studies carried out to date have provided hints of stunning new insights and seriously challenged previously assumed limits on peak flight altitudes inflight changes of altitudes and duration of individual flights in particular i have together with colleagues discovered a totally unexpected altitudinal behaviour some bird species change their flight altitude between night and day and fly at extremely high altitudes during the day up to 60008000 m but what makes a migratory bird fly as high as mount everest even when there are no mountains to cross by launching an extensive multisensor data logging programme combined with wind tunnel experiments and field studies the proposed project will change our understanding of the possibilities and limitations of bird migration this will be done by disentangling the causes and consequences of birds altitudinal behaviour the flexibility timing and duration of migratory flights if birds only use diurnal or nocturnal flights if they prolong flights to last both day and night or even fly nonstop between wintering and breeding grounds and the costs and consequences of these seemingly extreme behaviours
islands integrated sensing and communications for future vehicular systems a network of doctoral students

for decades communication systems have been developed independently to radar systems leading to a duplication of systems and devices that exploit the electromagnetic spectrum in common ways yet the future wireless infrastructure will need to do more than just communications to support smart cities intelligent mobility infrastructure monitoring security it will need to perform multiple functions and will rely on highreliability communication and sensing the independent growth of radar and communication systems is no longer sustainable and will lead to a congestion of devises emitters and sensors there is a skills gap in the community to address this as communication engineers work isolated to radar engineers and a new set of skills need to be developedislands is a doctoral network that focuses on the theoretical and algorithmic foundations of integrated sensing and communication for the automotive sector with the objective of developing new physicallayer and networklevel solutions to explore the fundamental limits of such technology and to provide experimental validation and testing for the developed techniques specifically islands will 1 develop new transceiver algorithms capable of integrating and leveraging the communication and sensing functionalities with the purpose of achieving superior performance and energy and hardware efficiency 2 investigate the ultimate network performance limits that the integration of communication and sensing can achieve in environments with extreme mobility and 3 provide experimental validations of the developed techniques with proofofconcept testbeds and realistic systemlevel simulators islands will train the next generation of eu experts and leaders with specific interdisciplinary expertise combining sensing and communications with the aim of reinforcing european leadership in the automotive sector of the next decades
relating qualities and quantities by resource approximation

qualitative type systems are a widespread technique exploited in the study of programming languages types allow to obtain relevant information on the behaviours of programs such as termination of the evaluation quantitative type systems are used to achieve additional information on complexity and resource consumption while these two families of type systems have been deeply studied their interaction is still far to be properly understood given a program typed in a qualitative way can we extract quantitative information from it in a compositional manner this very natural and fundamental question has not received any appropriate answer yet regalia aims to answer the question deepening our understanding of the relationship between these two kinds of type systems in order to do so regalia will further develop the theory of resource approximation by extending girards approximation theorems to proofs with cuts and by establishing a translation algorithm between qualitative systems and quantitative ones i shall then exploit these results to define modular methods to study programming languages alternative to taitgirard reducibility that will offer quantitative interpretation of relevant qualitative systems in the context of both pure and effectful computation
schrödinger bridges to open quantum systems

quantum systems are inherently stochastic at the quantum level randomness is introduced not only through the act of measurement but also due to the uncontrollable interaction with the surrounding environment indeed the precise manipulation of quantum dynamics presents a challenge for emerging quantum technologies such as computing simulation and quantum sensing on the other hand optimal transportation and brownianschrödinger bridges are of central importance in applications requiring regulation and estimation of classical stochastic processes these include unsupervised machine learning motion planning in robotics or protein docking and singlecell genomics in biology in this project we set out to extend these classical theories into the quantum domain specifically we will develop original methods to regulate and estimate the dynamics of open quantum systems the research will lead to powerful optimization tools for state steering quantum control of noisy quantum dynamics and will also provide novel insights into the thermodynamics of stochastic quantum processes furthermore the project will deliver new methods to characterize the dynamics of complex quantum systems that better fit experimental observations thus making a groundbreaking contribution to the theory of open quantum systems overall this research will bridge the gap between mathematics and the next generation of quantum technologies which will have broad implications from quantum thermodynamics to quantum sensing or coherent control
circular hydrometallurgy for energytransition metals

cirmet will lead to a new approach to hydrometallurgy called circular hydrometallurgy with a focus on the design of energyefficient flowsheets or unit processes that consume a minimum amount of reagents and produce virtually no waste cirmet has the ambitious goal to replace the traditional linear hydrometallurgical flowsheets for extraction and refining of the energytransition metals cobalt and nickel into a nextgeneration circular flowsheet which 1 consumes no chemicals other than green hydrogen water and carbon dioxide taking advantage of the unique chemical properties of carbon dioxide 2 uses the acid for the leaching process as a catalyst that is continually regenerated rather than consumed 3 reduces the net consumption of acids and bases to virtually zero through ingenious manipulations of chemical equilibria via solvent extraction and 4 comprises a virtually zero discharge of solid and liquid waste streams as such cirmet can drastically reduce the environmental footprint of hydrometallurgical processes to enable such circular flowsheets a new theoretical chemical thermodynamic framework for multiphase electrolyte equilibria involving two immiscible liquids and innovative unit operations for sustainable metal and sulphur recovery are developed hydrometallurgical processes are approached from a molecular level liquidliquid equilibria are modelled by gibbsenergyminimisation gem methods rather than by solving lawofmass action lma equations the proof of concept of circular flowsheets is demonstrated for metal recovery from real complex rather than synthetic impuritybearing input streams nickel laterites cobaltnickel sulphide ores mixed hydroxide precipitate mhp and mixed sulphide precipitate msp only by combining these three mutually supporting spheres of innovation 1 the thermodynamic framework 2 the unit process level and 3 the general flowsheet sphere can cirmet be successful
biobased fireretardant thermoplastic composites reinforced with natural fibres

one of the specific impacts of cbe ju programme is to replace at least 30 of fossilbased raw materials with biobased and biodegradable ones by 2030 potential scope for bioplastics manufacturing processes is foreseen in the coming decade the urgent need of increasing sustainability has also affected flame retardants during the last decades the number of studies based on developing biobased flame retardants has increased considerably together with their incorporation in formulations based on biobased polymers however the use of biobased flame retardants with biobased polymers has not been properly covered the thermofire project aims to be a pioneer in this field consequently the flame retardancy of the 100 biobased composites will be deeply developed and investigated fire retardancy is a key property of materials used for applications in the automotive aerospace and textile sectors due to the need to minimize fire risk and meet safety requirements in the thermofire project up to 100 biobased polymers will be reinforced with different natural fibers eg regenerated cellulose from wood and commercial flax and biobased flame retardants aiming at giving excellent flame retardancy to the final biobased thermoplastic tp composites the innovation of thermofire relies on the development of highperformance composites with a 20 reduction in weight and 15 in cost while maintaining the required levels of safety suitable for applications under stringent operating conditions thermofire project represents a genuine opportunity to remove europes dependence on imports of fossilbased polymers for stringent operating conditions in the aerospace automotive and textile sectors
democracy meets arts critical change labs for building democratic cultures through creative and narrative practices

the critical changelab project aims to reinvigorate the relationship between youth and democracy and consequently the future of 21st century european democracy this is achieved by spearheading the reach and impact of critical changelab model of democratic pedagogy fostering youths active democratic citizenship at a time where polarisation deep political divisions and declining trust in democracy are spreading across europe the critical changelab model for democratic pedagogy fosters learners transformative agency and strengthens democratic processes in education through collaborations across formal and nonformal education and local actors around globallocal challenges relevant for youth the model promotes creative and narrative practices to explore the historical roots of local and euwide challenges understanding the valuesystems and worldviews underlying distinct types of relations humanhuman humannature humantechnology at the critical changelabs young people are introduced to approaches such as theatre of the oppressed transmedia storytelling as well as speculative and critical design to rethink european democracy and envision justice oriented democracy futures throughout the lifespan of the project critical changelab aims to examine the current state of democracy within education institutions identifying youths perspectives on everyday democracy design a scalable and tailorable model of democratic pedagogy in formal and nonformal learning environments cocreate and implement the model with youth and stakeholders evaluate the model generating recommendations for policy and practice and develop strategies to sustain the model and its outcomes overtime through various research actions combining quantitative and qualitative approaches critical changelab will generate a robust evidence base to support democratic curriculum development using participatory and creative and critical approaches
energy planning and modelling through integrated assessment of climate land energy water nexus in subsaharan africa

achieving clean energy access and food security targets in subsaharan africa ssa will require significant infrastructure expansion improved policy environments and governance structures are recognised as vital in scaling up funding for climateresilient investments in renewable energy infrastructures the efficient exploitation of land energy and water resources and their synergised use for sustainable economic development as well as their robustness to stressors from climate change require integrated optimisation and assessment of strategic plans in these sectors working with existing widely adopted opensource modelling tools and data the epic africa project will build on the transparent integrated assessment and resource modelling connecting to the already existing community of developers and users the project will create a network of african experts to train cocreate and sustain the tools developed in the long term which is lacking at the moment the project will build advanced and spatially contextualised waterenergyfood wef models for longterm infrastructure planning operational wef models with sufficient temporal and spatial resolution will be developed and used to verify costoptimised infrastructure investment plans under different climate and socioeconomic scenarios epic africa sets out to support governance of sustainable development in ssa by forming and connecting a transition arena with stakeholders in dialogue leading to the development of a wef nexus digital engagement tool optimal use of shared resources will be exemplified for africa using the cases of the volta and tana river basins here we will design specific policy investment and infrastructure plans for the coming decades in the agricultural water and energy access sectors the project will produce a set of institutional regulatory and technical recommendations for sustainable management of optimised transition pathways
neuropeptidergic modulation of synaptic circuits in fear and anxiety

fear and anxiety are fear and anxiety are essential for survival adequate reactions to anticipated and perceived threats strongly depend on the current state context and previous experience what are the neurobiological mechanisms that underlie these adaptive behaviors while synaptic circuits are the backbone to process threat signals and transform them into behavioral responses increasing evidence suggests that neuropeptides tune these synaptic circuits in a state and contextdependent manner thus allowing for temporal control of excitability and plasticity neuropeptide receptors are abundantly expressed in neuronal circuits that regulate fear and anxiety in fact recent evidence suggests that most neurons synthesize multiple neuropeptides and in turn are regulated by multiple neuropeptide receptors that are expressed in highly cell typespecific patterns indeed genetic alterations in humans as well as pharmacological and genetic experiments in mice indicate important roles for multiple neuropeptides in regulating fear and anxiety and if dysfunctional increasing the risk for multiple neuropsychiatric disorders however due to the lack of specificity of existing tools the circuit mechanisms underlying these effects are largely unknown in this proposal i aim to reveal cell typespecific neuropeptidergic signaling mechanisms for contextdependent regulation of cortical circuit activity cellular excitability and synaptic plasticity i will use cuttingedge in vivo imaging and circuit manipulation tools combined with region and cell typespecific crisprcas9mediated genetic ablation to reveal how these neuropeptidergic signaling mechanisms regulate behavioral responses in the context of fear and anxiety this multidisciplinary approach will allow me to gain unprecedented mechanistic insights into how neuropeptides drive adaptive circuit computations and how their dysfunction underlies maladaptive behavioral and emotional responses to external cues