Dragon09/odtu_chatbot huggingface dataset:
dynamic control in hybrid plasmonic nanopores road to next generation multiplexed single molecule detection

in the quest to develop platforms to decipher the information in biomolecules there is an increasingly demand for techniques that are capable of identifying specific biomolecules at the smallest possible concentration controlling their capturing and movement at the nanoscale nanopore sequencing is a key technology to drive this progress and solidstate nanopores can be a major technological player in the field of solidstate nanopores many challenges remain in particular toward i design and fabricate nanopore with size comparable to biological pores ii dynamic control of single molecule translocation and iii multiplexed readout progress toward integrated platforms where both solidstate and biological nanostructures are implemented has been brought by the development of functional nanomaterials and dna nanotechnology able to address the importance of nanoscale precision in nanopore platforms with the potential to surpass the performance of biological nanopores yet the integration of biological and synthetic nanomaterials is technically challenging and their use to fully control and measure single molecule is far from realworld applications dynamo is designed as an innovative research and training network where we will recruit 10 researchers to work toward the ambitious goal of developing the nextgeneration single molecule technologies exploiting hybrid dna and metallic nanostructures the network brings together a unique team of 8 worldleading academics and 1 high tech innovative company at the forefront of optical spectroscopy dna nanostructures nanopore technology developments single molecule detection and control and biotech realworld applications dynamo will establish an intersectoral training and research programme at the physicschemistrybiotech interface with partners from 6 eu countries aimed at creating the next generation of skilled wellconnected scientists that will pioneer the single molecule science of tomorrow
enhanced understanding of trade impacts on climate industries and the environment

despite the wide recognition of the complex interactions between trade policy and climate policy the stateoftheart capabilities in macroeconomic models face substantial limitations such as lack of granular data dependence on conventional trade theories limited empirical evidence on tradeclimate interactions limited representation of the value and material chain in key existing and emerging sectors heavy reliance on frameworks not accounting for endogenous technical change limited understanding of the role of developing countries in trade etcentice aims to develop novel data and modelling capacity to enhance our knowledge and inform policymakers on the positive and negative impacts of trade and trade policy on climate and the environment by combining wellestablished macroeconomic modelling with new trade theories empirical analysis and enhanced data granularity the project will focus on emissions and climate change issues but also integrate the broader effects on the environment biodiversity pollution and natural resources depletion the entice work programme includes a novel theoretical conceptualisation of trade climate environment and industry interactions significant improvements to sectoral detail and relevant granularity in the gtap database integrating the new data into and enhancing a toolbox of wellrenowned cge macroeconometric integrated assessment and sectoral models and other methodologies and analysis of the interactions between trade policy climate policy the environment and broader economic and sustainability objectives in the eu and beyond finally entice places considerable emphasis on transparency legitimacy and open science and data as well as on development and research that directly respond to stakeholder needs and trade and climate policy discourse
empowering edge ai with systolic arrays

the primary aim of edgesa is to investigate the potential suitability and applications of systolic arrays sa and evolvable hardware ehw as acceleration solutions for data processing challenges that demand extensive computation at the edge especially crucial for resourceconstrained devices these technologies can serve as supporting mechanisms alongside existing technologies like artificial neural networks ann additionally indoor tracking of assets is considered as a realworld application context to enhance and validate the research since at present there is no reliable commercial solution available in the market that can deliver high accuracy
fundamental study of siderophoremetal complexes with electrospray ionization insource activation ion mobilitymass spectrometry

the electrospray ionization with mass spectrometry detection esims has been widely used to study biomolecules low molecular weight compounds and noncovalent complexes ion mobility spectrometry ims capable of separating ions with the same mz but varying sizes and shapes in the gaseous phase has been recently hyphenated with the esims to conduct fundamental and applied research the overall objective of this proposal is to generate new knowledge on the biological function and chemical characteristics of siderophoremetal complexes smcs under real conditions such as seawater and rhizosphere by harnessing insource activation isa and cuttingedge esiimms technology to this end the experimental investigations will involve varying esi parameters such as esi and isa voltages and drying gas temperature and solution conditions eg ph solvent type ionic strength and matrix to investigate stability and competitivity hydrolysis hydrogendeuterium exchange behavior and fragmentation patterns of smcs plus finding the binding site locations of siderophores to metal ions in smcs the proposed project will also include experimental and theoretical calculations of collision crosssection ccs values and thermodynamic studies via quantummechanical methods ie density functional theory to rationalize the experimental observations the obtained ccs values will allow us to derive additional structural and spatial information on the investigated smcs the proposed project is multidisciplinary in nature as it integrates analytical chemistry soilplant research environmental science physical chemistry and quantum mechanics twoway knowledge transfer in this project ensures the transfer of the candidates expertise in the areas of sample preparation flow systems and 3dprinting technology to the host institution and training of the candidate in advanced analytical chemistry techniques to enhance his employability and career development
cultural and creatives industries as innovative drivers to improve urban quality of life

the spanish presidency of the council of the european union will held during the second semester of 2023 a european conference entitled cultural and creative industries cities and citizens fostering sustainable development and the european way of living the objective is to reflect how the cultural and creatives industries ccis collaborate and contribute to improve peoples quality of life by creating solutions through culture and sciencethe event will pretend to be an international meeting point between culture and science by displaying in a demonstrative interactive and participatory way ccis european and collaborative projects and initiatives that are not only innovative and sustainable but also accessible affordable socially committed and enriching for all in line with the new european bauhaus neb initiative in this way the event will be able to reflect how cultural and creative industries can collaborate as social and innovative drivers through a collaborative networkthe conference will be organized held on 11 12 and 13 july 2023 in barcelona by the spanish foundation for science and technology fecyt in partnership with the spanish ministry of science and innovation and the spanish ministry of culture and sports
functional nucleic acids as versatile smart building blocks in nonconventional solvents

almost half of the production costs in the rapidly growing chiral chemicals market is spent on the downstream processing costs due to challenging separation tasks and demanding levels of purification funambulist aims at a radically new scienceenabled production of fine chemicals by emulating the ingenuity of biological processes in an engineered environment in this way funambulist aims at overcoming the current dogma that fine chemicals are produced via traditional synthetic routes in organic solvents funambulist creates a modular toolkit that enables a radically different approach to design chemical reactions in the fine chemicals market by abandoning the current artificial gap between biological and chemical function
enhancing earth observation capabilities of the eratosthenes centre of excellence on disaster risk reduction through artificial intelligence

artificial intelligence ai has a major impact on many sectors and its influence is predicted to expand rapidly in the coming years one area where there is considerable untapped potential for ai is in the field of earth observation where it can be used to manage large datasets find new insights in data and generate new products and services ai is one of the missing core areas that need to be integrated in the eo capabilities of the eratosthenes centre of excellence ecoe aiobserver project aims to significantly strengthen and stimulate the scientific excellence and innovation capacity as well as the research management and administrative skills of the ecoe through several capacity building activities on ai for eo applications in the disaster risk reduction thematic area upgrading and modernising its existing department of resilient society as well as its research management and administration departments and assisting the ecoe to reach its longterm objective of raised excellence on ai for eo on environmental hazards a close and strategic partnership between the ecoe from cyprus widening country and two internationally topclass leading research institutions the german research centre for artificial intelligence dfki from germany and the university of rome tor vergata unitov from italy will be achieved leading to a research exploratory project on the application of ai on eo for multihazard monitoring and assessment in cyprus moreover cellock ltd clk the projects industrial partner will lead the commercialisation exploitation and product development aspects of aiobserver and its exploratory project outputs all outputs will be disseminated and communicated to stakeholders the research community and the public assisting the ecoe to accomplish its exploitation goals by creating strong links with various stakeholders from academia and industry in cyprus and beyond that ecoe will capitalise on long after the end of the project
integrating innovations for the protection and restoration of european lakes

the overarching objective of futurelakes is to demonstrate innovative solutions needed to transform lake restoration integrated into lake management these aim to significantly improve ecological and chemical status of european lakes restore biodiversity recover valuable resources enhance the services that lakes provide and make society more resilient to climate change futurelakes aims to deliver this through an integrated framework for lake protection and restoration that demonstrates a range of technical solutions that include innovations in naturebased solutions circular blue economy solutions and biodiversityfocused solutions demonstrating integration of these solutions in operational lake management in six large european lakes demo basins which will deliver a blueprint for lake protection and restoration the futurelakes blueprint will incorporate a catalogue of innovations and guidance on the enabling environment needed to turn promising technical innovations from niche measures to become mainstream approaches in lake basin management planning this includes demonstrating more effective and inclusive collaboration in water governance and showcasing innovations in policy implementation and green financing futurelakes will also develop a roadmap for upscaling european lake restoration in support of the mission restore our ocean and waters deployment and upscaling phase upscaling of measures across europe will be tested through activities aimed at replicating the futurelakes approach in three associated regions futurelakes will not only contribute to delivering to the three objectives of the mission to protect and restore freshwater ecosystems and their biodiversity to reduce pollution and to build a sustainable carbonneutral and circular blue economy but it includes specific objectives to develop the missions two enablers creating a european lakes digital innovation hub and demonstrating innovative approaches to enhancing public engagement
demonstration of a cns data service provision cns dsp

cns dsp data service provider refers to the development of digital platforms and services leveraging stateoftheart technologies to enable future datasharing service delivery models it aims at sharing cns data between ansp and providing to other stakeholders civil military airspace users industry airport authorities regulators atm organizations aircraft manufacturersthe project aims at implementing a demonstrator based on several ansps data and for the usage of third parties applicationservice developers supporting adsp conceptthe cns data service provision project hereinafter referred as cns dsp aims to support the transition to the new service delivery model for atm data through the development of a new sesar solution the shared cns data services platform this solution will deliver the cns data services required by atc airspace users in full consistency with the adsp concept it will also offer a bunch of added value services for various aviation and utm stakeholders enabling the valorisation of ansps cns data for the entire aviation community
mapping and matching content diversity and bias in eu online social networks

polarscopeu proposes an original application tailored for the context of different eu countries that will measure and map in twodimensional spaces the polarisation of their online social networks this tool to be made available first in greece portugal and spain addresses not only the impact that online political communication and misinformation is having nowadays on democratic institutions but also citizens unawareness of existing biases in the online political information that they are exposed to more concretely relying on automated analyses of social media content to assess politicisation levels of multiple key issues this application will allow its users to 1 better understand how they place in terms of the online content that they create and consume in two major dimensions of political content diversity and bias and 2 find out which actors are closer to them when it comes to the politicisation of several important issues eg european integration immigration environment in order to create this application the polarscopeu will develop two additional products of extreme value for researchers and organisations to study and monitor online political communication the first one is an innovative tool to measure using alternative sources of text data the levels of salience and contestation of different political issues the second product is a periodically updated database for each country with polarisation and issue politicisation scores for an extensive list of national actors including political parties news media and other key opinion makers these products will facilitate the comparison of issue politicisation across countries time periods and actors and originate an innovative polarisation index of online political communication in the eu countries
an open ecosystem for european strategic autonomy and interoperability across the computing continuum industry

opencontinuum addresses the coordination and support of the cloudedgeiot domain with a specific thematic focus on the supplyside of the computing continuum landscapean integrated open ecosystem built around open source open standards and the effective blending of the two vibrant european communities of cloud computing and internet of things iot is the key enabler for european prosperity in the cloudedgeiot domain and more widely in the data economy therefore the core ambition of opencontinuum is fostering european strategic autonomy and interoperability through an open ecosystem for the computing continuum such an ecosystem will contain the research and innovation projects in the cloudedgeiot portfolio to be coordinated the diverse community evolved from the current cloud and iot ones with the addition of further actors initiatives and alliances of significance the supplyside nature of opencontinuums agenda will orient the themes and focus of the project activities but will not limit the scope of the community building the active landscaping and engagement work of the project will be key to bring the cloud and iot communities together and to express all points of view with a common language and understanding opencontinuum will then provide strong guidance and support to european computing continuum actors to contribute to and lead opensource projects and standardisation effortskey project contributions to the relevant expected outcomes include a baseline common open architecture for computing continuum research projects reinforced collaboration between european public and private initiatives from cloud to edge to iot and increased awareness on the importance of open source and standards for eu digital autonomy these contributions arising from project results will evolve further towards largerscale impacts and strategic objectives for european technological economic and societal advancement
monitoring investigation and response to cyberattacks with an adaptive digital twin model for agile services over the computing continuum

the growing level of interconnectedness of digital services and infrastructures creates tight and recursive security interdependencies between their providers which are challenging to address due to the fragmentation of cybersecurity operations this requires each provider to improve the security posture of its suppliers however existing practice largely based on human interaction for disclosing vulnerabilities reporting alerts and suggesting remediations demonstrates to be largely ineffective and riskythe miranda project aims at operationalising awareness and remediation controls for service supply chains by addressing feasibility acceptance and compliance issues to this purpose miranda develops a cybersecurity digital twin cdt to model and capture the security posture of such interconnected systems which is used to detect hunt and remediate threats and attacks the cdt will feature i functional and topological representation of digital services ii bidirectional controlmonitoring data flow with real systems iii modelling and behavioural prediction of individual components and whole systems iv opaque representation of suppliers assets based on confidentiality and privacy requirements the framework also encompasses the necessary security controls to safely exchange data and controls between providers on top of the cdt abstraction miranda builds adaptive and automated processes for threat hunting detection of lateral movements and eradication of the root causes of attacksvalidation of individual components and the overall miranda platform will be conducted in three relevant use cases covering different platforms for smart city services the purpose will be to demonstrate the adaptability to the evolving context and the effectiveness to stop latestgeneration cyber killchains and lateral movements across digital chains the project will also consider the new business and operational models that are required to run the platform
retinal mesh optoelectronics

visual sense is vital for all of us blindness has severe negative psychological social and economical consequences and degeneration of photoreceptors is a leading cause of it photovoltaic retina implants are the current electronic solution to restore vision loss due to photoreceptor degeneration since the stateoftheart implants are based on photodiodes which face challenges in terms of miniaturization efficiency and compatibility with mechanical and structural properties of the retina artificial vision still falls short to overcome the legal blindness level we propose a novel concept of retinal mesh optoelectronics that will simultaneously satisfy a highpixel density for high visual acuity b conformability to match the natural curvature of the retina for optimal vision quality c flexibility for coverage of a large area of the retina for a wide field of view d seamless integration to keep the remaining healthy photoreceptors intact e biocompatibility f usage of safe capacitive current g injectability and h removability toward this aim we will initially develop efficient thin and cellularsized photovoltaic neural interfaces based on quantum dots and nanowires for that nontoxic quantum dots that have strong light absorption at nearinfrared will be synergized with the nanowires that have unique lighttrapping and high surface area for efficient photostimulation of neurons then we will translate these devices to porous and flexible tissuelike retinal implants for artificial vision starting from the nanomaterial synthesis to optoelectronic device fabrication and bioelectronic mesh formation this challenging innovation combining nanomaterials photonics and abioticbiotic interfaces will be explored from primary neurons up to invivo experimental models of photoreceptor degeneration in order to move the results toward clinical application
exposing spatiotemporal structures of turbulence in the atmospheric boundary layer with insitu measurements by a fleet of unmanned aerial systems

exchange and transport processes in the atmospheric boundary layer abl are driven by turbulence on a wide range of scales their adequate parameterization in numerical weather prediction nwp models is essential for a high predictive skill of forecasts in heterogenous and complex terrain the common simplification of turbulence to statistical models does not necessarily hold coherent structures such as convective cells secondary circulations gusts slope and valley flows can be summarized to submesoscale structures which are not well represented in models a reason for the lack of understanding of these flow features is the challenge to adequately sample their spatiotemporal structure and their contribution to the energy budget of the abl the project establisuas will provide methods to expose spatiotemporal structures in the abl with insitu measurements by a fleet of unmanned aerial systems uas for this purpose small rotarywing uas will be enabled to measure threedimensional wind temperature and humidity in organized spatially distributed networks the project will include a threefold approach to validate single uas measurements fleet observations and methods to derive spatial averages and fluxes wind tunnel tests field experiments and virtual measurements in numerical simulations will be performedthe validated uas fleet will be deployed in two campaigns in the framework of the teamx research programme focusing on the mountain boundary layer mobl the establisuas measurements will fill observational gaps in the submesoscale the analysis of the uas fleet data in synthesis with ground observations and remote sensing will provide unprecedented new insights into the complex mobl flow and the components of its energy budget the results will foster the development of new and better parameterization of the abl in complex terrain