Dragon09/odtu_chatbot huggingface dataset:
spacious and accurate mri machines of the future

we aim to pioneer the next generation of mri machines which are less scary for claustrophobic patients more accessible for the underserved population eg obese patients patients with medical implants in their body more accurate for radiologists and more cost effective for the manufacturerwe developed a novel mri field homogenization technology which is 50x lighter 5x more power efficient performs 2x better and updates 250x faster than the current stateoftheart for the first time we enable realtime precise and local control of the mri magnetic field using a compact deviceour aim in this project is to substantiate our value proposition and evidence of safetyperformance through solid data generation and disseminate the data to all relevant stakeholders to improve our market position and consolidate our longterm commercialization plansas a company whose ultimate goal is to make mris accessible everywhere we put diversity and inclusion at the forefront of our mission statement as we head towards the next growth stage of our company we hope to set the right diversity and inclusion goals and diversify our network through engagement with the women techeu program
laserassisted synthesis of magnetically motile plasmonic chiral nanocatalysts

catalysis holds immense significance in chemical manufacturing being a key player in developing sustainable industrial processes with limited energy resource consumption in pharmaceutical industry catalysis is crucial for enabling mass production of affordable lifesaving drugs however developing efficient catalysts for this sector poses a formidable challenge due to the inherent asymmetry of many biological processes this is particularly critical in producing anticancer drugs because their synthesis relies on intermediates or reactions whose asymmetric nature known as chirality withholds their massive production limiting equal global access to best health treatmentsan upandcoming solution to address this dilemma is resorting to chiral plasmonic nanoparticles nps as their outstanding optical rotation activity makes them wellsuited for applications like polarizationsensitive photocatalysis especially in the context of anticancer drug development however unleashing its full potential hinges on imbuing these chiral nps with unusual properties like magnetism allowing safe removal from products recyclability without generating chemical waste to date creating a plasmonic structure that seamlessly integrates chirality with magnetic motility remains largely underexploredthe lymon project addresses this conundrum by expanding the repertoire of chiral nanocatalyst construction methods through a groundbreaking laserbased pathway this innovative approach supported both experimentally theoretically promises to bring a new generation of highly specific magnetic chiroplasmonic nanocatalysts characterized by their ability to be reused multiple times all of this permiting reducing wasteful side reactions improving control over pharmaceutical production especially for anticancer drugs moreover it promises to expand the horizons of synthetic chemistry paving the way for cuttingedge routes to produce highly efficient selective molecules
towards competitive reliable safe and sustainable concentrated solar power csp plants

this training project topcsp will offer 10 promising doctoral candidates a unique international intersectoral and interdisciplinary research and innovation framework that will boost their excellence in the development of innovative technologies capable of solving the challenges currently faced by the solar thermal power industry in the eu and worldwide concentrating solar power csp with thermal energy storage tes is a key technology to support the transition to a competitive and sustainable energy system however an effort is needed to make this technology competitive by increasing its efficiency reducing its costs and improving its reliability and environmental profile topcsp project will include research activities aimed at reducing the cost of current csp plant increasing the temperature of the heat transfer media of the next generation of csp plants developing more efficient power blocks and optimizing the plant design csp research requires highlevel human resources covering a wide range of competences topcsp will be able to train researchers with the technical knowledge and transferable skills needed to contribute to this aim from either the academic or the industrial sector the consortium of this proposal will provide balanced scientific and applied skills together with the global vision of the csp industry that will maximize the employability of the trained researchers the consortium comprises 8 academic beneficiaries with a long record of research on csp and two industrial beneficiaries which are leading companies in the sector the associated partners of the network include the largest rd test centre focused on csp in europe hightech companies specialized in the different subsystems of the csp plant an agency for new technologies energy and sustainable development and a training company specialized in ri project development and management
nonlinear inversion of correlation waveforms with hierarchical reconstructions

waves propagating through a complex medium provide a noninvasive way to probe its interior structures in ambient noise imaging the input data are the crosscorrelation of the stochastic wavefields to reconstruct the properties of the medium the waveform inversion is formulated as an optimization problem involving a misfit function whose convexity plays a critical role in the achievable spatial resolution of the inversion results especially in the absence of a priori information about the medium current inversions are often limited by computational cost crosstalk between the physical quantities and the use of singlescattering approximations project incorwave proposes to create a new mathematical and computational framework for nonlinear inversion of full waveform crosscorrelation two specific problems are considered first for the reconstruction of geophysical viscoelasticity tensors with applications to earths subsurface monitoring secondly for the reconstruction of threedimensional flows in the sun to characterize the poorly understood properties of deep solar convection to improve the convexity of misfit functions the inversion procedure of project incorwave will follow a hierarchical progression which is established by selecting subsets of input data unknown parameters and frequencies the choice of each of these subsets as well as the associated misfit function is controlled by criteria in form of convergence estimates indispensable to meaningful inversion is accurate modeling operators that describe the physics under consideration and that are adapted to the treatment of real data for the reconstruction of the elasticity tensor the project will develop a solver in terms of p and spotentials for heterogeneous media a 3d global sun vectorwave solver is created for the inversion of the convection component of the solar flow that does not bear symmetry
investigating the regulation of the senescenceassociated secretory phenotype sasp by mitochondrial dna mtdna metabolism for the development of novel senotherapies

in response to various stresses such as dna damage telomere erosion or oncogene activation human cells can enter senescence this process is characterized by irreversible proliferative arrest deep transcriptional reprogramming and expression of a collection of inflammatory factors termed the sasp senescenceassociated secretory phenotype as it limits the proliferation of cells potentially bearing neoplastic potential the triggering of cellular senescence is an essential tumor suppressing mechanism however the persistence and accumulation of senescent cells in aging and pathological contexts can have deleterious effects particularly due to the sasp it is thus fundamental to understand the basic physiology of senescent cells to develop socalled senomorphic drugs that modulate sasp expression changes in mitochondrial physiology elicited during cellular senescence onset strongly suggest that the maintenance and integrity of their mitochondrial dna mtdna may be altered for instance cytosolic leakage of mtdna has been shown to take place in senescent cells and participate in sasp expression via immune pathways activation but the contribution of mtdna metabolism and replication in sasp expression has not yet been explored my preliminary results show that mtdna copy number increases continuously during senescence progression accompanied by recomposing of the mitochondrial replisome i also showed that this increase in mtdna copy number promotes sasp expression in the present project i will characterize in details the alterations in mtdna maintenance and integrity during senescence profile the evolution of mitochondrial replisome composition and characterize how the previous regulate sasp expression the perspective of this project is to identify new senomorphic targets for controlling sasp expression and hereby alleviate the adverse effects of senescent cells in pathological contexts
cellular crosstalk driving tertiary lymphoid structure formation across tissues

formation of tertiary lymphoid structures tls is a recurring consequence of chronic tissue inflammation and autoimmunity as well as several solid tumours tls originate in various tissues from infiltrating cells attracted by local signalling cascades these structures can enhance local immune response by similarly to secondary lymphoid organs slo functioning as spots for lymphocyte activation upon antigen recognition however the cellular interactions driving tls emergence and function across tissues are not fully known this proposal aims to unravel and characterise the cellcell interactions involved in the formation and maintenance of tls in particular their tissue specificity and relationship to autoimmune diseases a comprehensive understanding of intercellular interactions will be obtained from publicly available and newly generated singlecell rnasequencing scrnaseq datasets from tlscontaining tissues of autoimmunity patients molecules involved in key signalling interactions will be spatially resolved by assessing their tissue expression using spatial transcriptomics then using mouse models where tls triggering can be controlled scrnaseq data will be obtained to outline a time course of tls formation in different tissues revealing the temporal role of the discovered interactions and their specific function in each tissue and when compared with slos finally regulation and downstream effects of ligands and receptors will be unraveled with multiome rnaopen chromatin sequencing using human tonsil organoids the observed effects will be generalised to other tissues using machine learning and deep learning models resulting in a tissuespecific reference of signalling and regulatory genes controlling tls biogenesis overall this project aspires to provide a detailed look into tls biology while defining the bases for their therapyoriented manipulation
palestinian youth at the crossroad comparative perspectives on palestinian transnational youth politics

this research project explores the political potential of contemporary palestinian transnational youth activism in the united states and europe it compares student political engagement namely by examining the formation and development of the general union of palestinian students gups during what is regarded as the golden age of the palestinian revolution 1960s1970s with contemporary initiatives efforts and strategies of mobilization amongst palestinian youth in diaspora by implementing both crossgenerational and transnational comparative frameworks this project provides a comprehensive mapping of youth and student experiences in the us and europe in order to evaluate what kind of initiatives are emerging and what capacity they hold in restructuring the palestinian national movement by looking to the past through a historical continuum that has molded present day palestinian youth activism this project proposes that new futures can only be made through methodologies that tether together time and space how have palestinian new generations responded to the political transformations that have informed the palestinian as well as the regional and international scenarios is there space for palestinian youth to contribute to the revitalization of a paralyzed national movement within a transnational framework able to appreciate the diverse sociopolitical economic and cultural backgrounds that characterize contemporary palestinian societythis project address these questions by providing a comparative analysis of two different political moments of palestinian history the preoslo and the post oslo periods this comparison allows the understanding of how youth politics has evolved over time and across space and what mechanisms can or cannot be reproduced within the broader palestinian political context in doing so the study will allow new empiricallybased deductions on the general state of palestinian politics and its future perspectives
enhancing the scientific capacity of tubitak mam in the field of smart environmental technologies for climate change challenges

smart4env aims to improve tubitak marmara research center tubitak mam ri capacities to strengthen its scientific reputation attractiveness and networking channels while stimulating scientific excellence in the field of smart environmental solutions ses for climate change adaptation and mitigation of key applications for the turkish economy within water agriculture and public health sectors it will reinforce ri and knowledge transfer capacity of tubitak mam the project will develop capacity building of permanent scientists earlystage researchers esr training enlarge cooperation between academia industry and stakeholders in turkey with a general sustainable framework for research international networking mobility and integration in the european research area era strengthening the experience of the research staff of tubitak mam including a new generation of young scientists will be developed through the cooperation with eu partners of established scientific excellence in the topics and demonstrated experience in economic impact and awareness raising and integration into national policies at scientific level it is expected to enlarge the community of competitive prestigious researchers at tubitak mam in ses stronger and betterconnected to a core of international and relevant ri systems supported by skilled ri managers with their international networks at social level it is expected an improvement in environmental quality public health improved customer experience and communication a better mitigation and adaptation to climate change because of new ses for intelligent connected and responsive environmental services and a sustainable use of water and resilient treatment systems with stable effluents quality at an economic level the project will contribute to the development of an innovative ses industry and the profitability of regional companies through new product development process improvements innovation support and job creation
decolonizing international biodiversity law digital sequence information as a revealer

access benefit sharing abs mechanisms where access to genetic resources generally in developing countries is bargained against benefits used for conservation actions were formed to mitigate deep inequalities between countries and biodiversity actors originating in the colonial history of plant genetic resources collection and use however these inequalities are currently under threat by technological innovation such as digital sequence information dsi which alter the nature of biobased rd dsi revives the past abs fight between the global north and south over the control of genetic resource it is thus urgent to unpack the issues at stake by listening to all actors involved in biodiversity conservation and dsi innovation in response decolawbiodiv proposes a novel approach to explore how a decolonial reading of biodiversity conservation law can contribute to reach the international objectives of biodiversity conservation laws sustainable use and fair and equitable abs decolawbiodiv will dig to the roots of the abs northsouth divide and 1 account for actors interactions including power games in negotiation arenas 2 highlight the multiple actor groups understandings of key abs concepts rights and obligations and 3 scrutinize the negotiation processes using a decolonial lens decolawbiodivs theoretical groundbreaking nature lies in the holistic study of dsi within the abs marketbased legal and institutional frameworks using conflict transformation theory the methodological originality is to spell out the decolonial lens through the circle of dialogue of wisdom method in 3 case studies bolivia india south africa in order to transform the absdsi conflict into mutual understanding and support between actors and lead to a decolonized cocreation of knowledge for an effective international biodiversity conservation legal regime
carbon negative biofuels from organic waste

carbiow project addresses green transition and circular economy by proposing novel technologies that cover the whole process of conversion of organic waste to biofuels on one hand hardtoutilize organic waste such as organic fraction of municipal solid waste and residues from biorefinery and biological processes are utilized to highlight a new bioenergy source on the other hand new technologies will be developed from trl 2 to 5 the proposed technologies via carbiow enable europe to take the lead and advancement in several fields of energy generation and energy sector decarbonization moreover energy security economical boost local energy independence and job creation are addressed torrefaction as an emerging technology converts the very heterogeneous and wet organic waste to a highquality solid biofuel besides torgas will be combusted with oxygen to generate energy for torrefaction and to obtain nearly pure co2 a novel technology ie oxygenblown gasification in oxygen carrier aided systems will convert the torrefied organic waste to clean syngas with very high efficiency in terms of energy and yield the syngas will be used in the fischertropsch process with a novel reactor and novel 3d printed catalysts aiming to produce aviation kerosene and marine alcohols biofuels the co2 from the oxyconversion steps will be fixed in the resulting ashes from the same process via carbonization to make cementbased product so carbiow addresses another goal that is the decarbonization of cement industry while making the biofuels to be carbon negative the diversity and strength of the experts within the consortium of carbiow will guarantee the technological technical and societal advancement of what is proposed most importantly the exploitation and perspective of the whole process will be evaluated by the leaders and industrial sites to pledge the feasibility of the scaleup and further development of the proposed process
chaos and thermal effects in black hole interactions

the understanding of the microscopic origin of chaos and thermal effects in the physics of black holes is very challenging such fundamental aspects seem to be intimately connected but a microscopic analytical description of their interplay is still missing the quantum gravity description of these aspects could help clarify their microscopic interconnection the project i propose has the ambition to probe black hole states through highly excited string and coherent string states providing a quantum microscopic description of chaos thermal effects and information theory the main observables are scattering and decay processes the research programme contains the following parts first a general strategy will be developed to measure and analytically control chaos in physical processes involving black holes such as black hole decays and black hole compton scattering in particular a quantitative measure of chaos will be introduced using random matrix theory techniques and the relative lyapunov exponents will be computed second in order to study thermal effects in black hole processes the triggering of the thermalization phase driven by chaos will be investigated finally the project will consider the following direct applications the first one will be the study of chaotic signatures in wave forms and quasinormal modes of gravitational and electromagnetic waves the second will concern the realization of black hole horizons in terms of highly excited string and coherent string form factors
labtotech transition of the current best low temperature electrolyser technology for co2 reduction to co using solar energy

one of the most important challenges of humanity is to maintain economic growth and wellbeing in an environmentally sustainable way the european green deal addresses this issue and it aims at making europe climate neutral by 2050 to reach this aim a high priority opportunity is the utilisation of waste carbon dioxide to produce valuable chemicals eg energy carriers fine chemicals pharmaceuticals in an environmentally and economically sustainable manner in our previous erc proof of concept project we have demonstrated that the most viable approach where sunlight is first converted to electricity by a solar photovoltaic pv cell and co2 is then reduced electrochemically to carbon monoxide which can be further processed to valuable chemicals the technoeconomic analysis performed during the erc poc project confirmed the competitiveness of this solar energy conversion approach our team developed the current best performing low temperature co2 electrolyser cell at laboratory scale published the results in nature energy and filed two pct patent applications regarding this technology the aim of this project is to translate our scientific and technological excellence to a commercially appealing value proposition our objective is to develop build and operate a containerised demonstrator scale co2 electrolyser unit capable of processing 100 t co2year as well as to validate its performance using photovoltaic power we aim to perform a detailed technoeconomic assessment and develop a business plan to attract investors in order to scale the technology further and start its commercialization by the end of the project we aim to become ready for series a investment andor eicaccelerator blended finance the success of this project will represent a genuine breakthrough in the field of carbon capture and utilization ccu enhancing european leadership in this emerging market and a significant contribution to green deal objectives