Dragon09/odtu_chatbot huggingface dataset:
enabling underused biowaste feedstocks into safe and effective marketready soil improvers

soil degradation is considered a global emergency 6070 of eu soils are degraded due to unsustainable management practices biosoilutions aims to tackle this problem by building upon previous key eu projects involving key consortium partners and bringing them forward the main ones being waystup savcoord draxis valuewaste cetenmacoord nuresys gaiker and entomo and scalibur cscp and ge we will optimise four biowaste valorisation routes blood hydrolysate frass nstruvite kstruvite into advanced biowaste soil improvers with the aim of enhancing nutrient recovery from biowaste eg n p k organic matter thus reducing landfilling and incineration these valorisation routes will render a range of biowaste feedstocks that will be combined in different formulations together with key additives eg nonmicrobial plant bioestimulants nmpb microbial plant bio stimulants mpb and controlled nutrient release coatings cnrcs into at least five biowaste soil improvers they will be cocreated by working along with three living labs in flanders belgium valencia and murciaspain involving critical soil sector actors companies and entrepreneurs endusers research centres public bodies and civil society to guarantee a good market fit of the developed soil improvers coverage of sectorial needs and compliance with regulatory requirements eg new fertilising products regulation moreover we will design an upscaling roadmap and a circular business model for each valorisation route to engage entrepreneurs and relevant soil companies to foster the commercialisation of advanced biowaste soil improvers across the eu biosoilutions longterm impacts will contribute to reach targets of key eu policies and international commitments including the european green deal and un sustainable development goals 6 8 9 11 12 13 14 and 15
hybridization derived novel patterns of gene expression

hybridization has been documented to the extent where its importance for generating evolutionary novelty can no longer be questioned in spite of this we lack an understanding of the evolution of regulation of gene expression in hybrids and its role in hybridization derived novelty gene expression evolves in a stabilizing manner where cislocal and transdistal regulatory elements coevolve as hybridization breaks up coinheritance of regulatory elements transgressive hybrid expression patterns transcending the ranges of both parent species may arise in spite of intermediate genome composition i propose to leverage my finding of transgressive gene expression in a wild hybrid species and address how hybridization produces transgressive gene expression this research will give insights into how hybridization can contribute to the arrival of the fittest by producing novel variation that selection can act onobjectives 1 to determine how regulation of gene expression in hybrids can produce evolutionary novelty 2 to unravel the roles of hybridization induced transposable elementreleases alterations of methylation and larger structural variants in hybrid specific gene expression 3 to uncover the role of gene expression in avian hybrid sterility i will use four independent hybrid lineages of the italian sparrow and experimental f1 hybrids to achieve these ambitious goals hybridexpress will i uncover how hybrid gene expression can transcend parental ranges producing evolutionary novelty ii contribute insights into how the variation selection acts on arises iii increase our understanding of hybrid genotypephenotype maps and iv reveal the role of hybrid misexpression in reproductive isolationinterdisciplinary character this proposal will make extensive use of genomic methods and hence overlaps to some degree with the ls2 panel but as the question addressed is evolutionary i deem the proposal best suited for evaluation by the ls8 panel
curvature aspects of rigidity and flexibility of complex manifolds

this research program will address the curvature properties of two important classes of complex manifolds kobayashi hyperbolic manifolds and oka manifolds these manifolds are characterized by a degree of holomorphic rigidity and flexibility respectively and have appeared in many branches of mathematics from number theory to algebraic and differential geometry a grasp of the curvature properties of these manifolds will offer valuable insights into their geometry facilitate the generation of examples and elucidate their relationship to important classes of manifoldsfor instance rationally connected manifolds which play a central role in algebraic geometry the experienced researcher er has established major improvements in the main techniques that are used in the differential geometric study of kobayashi hyperbolic manifolds namely the schwarz lemma on the other hand the field of oka manifolds has seen tremendous growth primarily from the work of the host supervisor who is the world leader in the subject and a world leader in complex analysis more generally the research program will not only merge these areas of expertise but also merge the complex analysis and differential geometry communities the action will consist of a high transfer of knowledge to the er the host supervisor and the host organization the results of the action will be disseminated through online video platforms within which the er has established himself as an experienced and proficient member
new governance models to enhance nutrient pollution handling and nutrients recycling

in a context of ecosystems pressured by nutrient pollution and recordhigh fertiliser prices the recovery of nitrogen and phosphorous from waste streams provides a solution to tackle both issues allowing the supply of new fertilisers and other products for the food value chain at a competitive price while enabling cleaner soil air and water systems however to effectively do so an intensive political regulatory and governance effort is required to bring all key stakeholders on boardnenuphar was conceived to solve this need by developing new governance and value chain solutions addressing three waste streams widely present and the eu manure sewage sludges and dairy wastewaters addressing four main innovations i a methodology for estimating np emissions from the application of a fertiliser on soil ii new governance models based on a network governance approach iii innovative economic and financial incentives for public and private entities iv enabling technologies to treat manure sludges and dairy wastewaters to recover the nutrient loadsnenuphar approach will be demonstrated in three different regional clusters from geographically diverse river basins the ebro river basin spain the lielupe river basin latvialithuania and the danube river basin hungaryslovakia branch and they will be replicated in two insular systems cyprus and bornholm denmark all the regions involved gather a population of 54 m people and an area of 109000 km2this demonstration will allow the direct recovery of 273 ton of n and 72 ton of p while the involved regions shows and overall potential of 383 mton of manure 252 kton of dry sludges and 43 m3 of dairy wastewater that can be treatednenuphar will employ a multistakeholder approach gathering 21 entities representing farmers and irrigators waste managers research experts in circularity and agronomics social science experts environmental organisations and public administrations
piezoelectric biomolecules for leadfree reliable ecofriendly electronics

billions of piezoelectric sensors are produced every year improving the efficiency of many current and emerging technologies by interconverting electrical and mechanical energy they enable medical device infrastructure automotive and aerospace industries but with a huge environmental cost the majority of piezoelectric sensors contain lead zirconium titanate pzt the fabrication of which requires toxic lead oxide prominent leadfree alternatives are heavily processed and rely on expensive nonrenewable materials such as niobium biological materials such as amino acids and peptides have emerged as exciting new piezoelectrics biomolecularcrystal assemblies can be grown at room temperature with no byproducts and do not require an external electric field to induce piezoelectricity unlike pzt and other piezoceramics currently no research is focused on developing these crystals as reliable solidstate sensors to integrate into conventional electronic devices due to their high water solubility uncontrolled growth variable piezoelectric response and difficulty in making electrical contactpbfree will take on the groundbreaking challenge of developing biomolecular crystals as organic lowcost highperformance sensors to outperform and phaseout inorganic device components with dramatically reduced environmental impact the project will rapidly accelerate the design growth and engineering of these novel piezoelectric materials under three pillars an ambitious computational workflow will enable the design of superpiezoelectric crystalline assemblies by combining highthroughput quantum mechanical calculations with machine learning algorithms a new method of growing polycrystalline biomolecules will be developed allowing for easy efficient creation of macroscopic piezoelectric structures a stateoftheart electromechanical testing suite will be established to characterise fully insulated and contacted biomolecular device components
2d materials enabled wide spectrum image sensors and optical neural network based low power consumption computer vision

from the late 1950s computer vision cv a significant field of artificial intelligence ai began to be the tool to realize human intelligence and perception today the global computer vision market has a value of over 11 billion and will reach 19 billion in 2027 current computer vision systems suffer from high power consumption and limited reliability due to the low amount of information captured and sensor malfunction in adverse conditions such as fog darkness and bright sunlight the 2dneuralvision project aims to develop the enabling photonic and electronic integrated circuit components for a novel lowpower consumption any weather any light computer vision system these components are a 2dm enhanced widespectrum image sensor and optical neural network with enabling 2dm components nontoxic materials and new waferscale cmoscompatible backendofline integration processes for 2dms will be developed to show compatibility with highvolume markets the developments in the 2dneuralvision project will result in reliable any weather any light low cost 1000x lower low power consumption 30x lower and small form factor 1000x lower computer vision systems this will have enormous societal impacts by enabling disruptive improvements in the automotive arvr service robotic and mobile device sectors
technological intervention for development of circular agrifood system to produce proteins from minor cereals

cleanlabel plant proteins have gained a lot of financial research and consumer attention globally fostering a great interest of food scientists in exploring various alternative plant sources and technologies to fabricate proteinrich food products cereals being the major nutrient vehicle for the masses and proteins being the second most abundant nutrient in these minor cereals these grains can be a suitable alternative for plantbased proteins to meet the increased protein demands the united nations food and agriculture organization fao has declared 2023 the international year of millets and owing to its invaluable contribution to the worlds food supply not only millets but also other minor cereals are currently undergoing a revival when other grains fail due to rising global temperatures such minor cereals that can withstand drought are anticipated to provide food for the entire worlds population thus the overall aim of procereal is to generate highquality cereal proteins by transforming minor cereal flours like millets with a zerowaste approach procereal will employ novel green technologies to obtain highvalue protein ingredients for food applications and the sidestreams produced in the process would be explored for their potential for other highvalue ingredients this will allow the generation of new sustainable value chains for minor cereals like millets
the gene therapy innovation training network

gene therapy has transitioned from a distant hope to reality to date 3 raav gene therapies are approved in the eu 30 phase iii clinical trials ongoing and exciting developments in therapeutic gene editing in the pipeline however fundamental limitations in the bioprocessing of gene therapy vectors limit broader application manufacturing is not automated with an open process environment limited scalability and robustness and inefficient downstream processing resulting in huge footprint and exceedingly high cost of goods the field requires scalable manufacturing technology with modular design to produce high doses for large patient groups at a fraction of cost improved delivery approaches with increased specificity and efficacy at lower doses are needed to overcome emerging safety concerns observed in clinical trials prediction of therapeutic efficacy in man is challenging due to a species barrier underlining the need for humanized models to reduce attrition rates in the development pipelineto overcome these challenges innovation driven by multidisciplinary approaches is direly needed getin is a doctoral network of 7 academic and 8 nonacademic partners with expertise in vectorology genome editing process engineering biomanufacturing and innovative humanized models together they provide an excellent training framework for 10 doctoral candidates dcs who will be the future innovators in the gene therapy field research in getin will investigate disruptive innovations including optimised bioprocessing digital simulation novel and improved vectors and genome editors targeted delivery systems and human organonchip models for more relevant safety and efficacy evaluation the joint training programme will emphasise responsible cooperative research and innovation creativity and entrepreneurship to maximize the career potential of the dcs
energy efficiency building enhancement through performance guarantee tools

ebento is aiming to develop an integrated platform for all actors involved in building and renovation sector to provide onestopshop to better coordinate and manage energy performance contracting bringing together the needs from all actors involved in enhancing the building stockthrough ebento citizens will increase their implication in building energy efficiency enhancement and both public institutions and energy communities will be able to identify potential energy efficiency improvements in residential housing stock with smes and escos support furthermore with ebento platform new business models for optimizing the financial and indirectly other resources available will be validatedebento will explore the best financing and collaboration schemes to set up energy servicesebento will study how to enhance current energy performance contracting epc for demand side mechanism dsm services and what kind of investment options grants loans can be implemented to increase the number and impact of energy efficiency projects in the cityregionby using digital tools ebento will gather data from epcs financial schemes and energy savings to give to the citizens the required trust for investing in new solutions and to companies the relevant information to reduce costs and easily replicate the work developedebento will ensure the exchange of relevant information between the different actors making the renovation process costefficient and easy to operate and replicate the platform will collect data related to performance contracts and guarantees devices monitoring energy savings building information modelling users opinions and comfort levels among others
origami inspired thermoelectric generators by printing and folding

the transition towards an energysustainable society is the key challenge for the engineering sciences in the 21st century this proposal addresses the energy supply for the future trillion sensor devices that form the backbone of our digitized society and it addresses the possibility to recover huge amounts of lowtemperature waste heat in industry energyharvesting from lowtemperature environmental heat via thermoelectric generators teg is a versatile and maintenancefree solution for both challenges a prerequisite however is a costeffective and scalable materials and manufacturing strategy for such tegs orthogonal will explore the devices using novel printable thermoelectric nanocomposite materials and it will tackle the fabrication challenges of printed tegs based on ultrathin 2 m polymeric foils we will explore ntype and ptype inorganic printable nanomaterials with high efficiencies and will use them for large area 2d printing on ultrathin substrates by using photonic sintering we will nanosolder the thin teg films the tegs will then subsequently be fabricated by an origamiinspired folding process a customized machine will be designed and constructed to allow for an automated folding of the 2d foil into the desired 3d geometry as demonstrators the project will realize teg powered autonomous sensor nodes and a heat exchanger including a large area teg the work will build on my more than 30 years of experience in solid state semiconductor devices several key patents from my group and our recent proofofconcepts for the thermoelectric materials and the device design the design and fabrication principles of orthogonal will also be of use of other largearea electronic devices eg xray detectors thzmetamaterials and piezoelectric transceivers
development of a noninvasive medical device to measure the skin biomechanical properties assessment of the commercial feasibility

skin pathologies including wounds scars and tumors represent important public health issues eg melanoma is the first cancer in terms of increasing frequency moreover skin firmness is an essential property aimed by cosmetic products however skin assessment methods remain based on empirical considerations and it is still difficult to determine the skin biomechanical properties which prevents developing a personalized medicine approach such medical device is needed by the physicians to adapt the therapeutic strategy and by the cosmetic manufacturers to develop and validate their product and to propose the optimal product in a customerspecific mannerassesskin is based on results obtained in the erc cog project boneimplant and aims at developing and validating a medical device consisting in a decision supportsystem allowing to assess the skin biomechanical properties the objectives of assesskin are i to achieve a minimum viable product that will be validated in vitro and in vivo and ii to investigate its commercial potential and design an exploitation strategy via spinoff creation or licensing we will explore the possibility to license the technology to impactell an already existing spinoff of the same laboratory the originality is to use an impactbased measurement method which allows to obtain a noninvasive cheap and easy to use medical deviceregulatory issues will be at the heart of the development and we will work in order to clear the regulatory pathway of the future medical device the team is constituted by members with complementary skills engineers a business developer a dermatologist and a plastic surgeonassesskin will allow the promotion of innovative solution and services in dermatology plastic surgery and in the cosmetic industry the longterm vision is for the technology to become a reference in these fields strong impacts are associated to assesskin in particular for patients physicians and cosmetic manufacturers
towards full implementation of the km3net research infrastructure

km3net is a large research infrastructure comprising a network of deepsea neutrino telescopes in themediterranean sea with user ports for earth and sea sciences instrumentation the main science objectives a description of the technologyand a summary of the costs are presented in the km3net letter of intent following the appearance of km3net onthe esfri roadmap 2016 and in line with the recommendations of the assessment expert group this proposaladdresses the coordination and support actions csa to prepare a legal entity for km3net and establish open access to the ri thereby providing a sustainable solution for the operation of the research infrastructure during ten or more years during the eufundeddesign study 2006 2010 and preparatory phase 20082012 a costeffective technology was developed deepsea siteswere selected and the collaboration was formed this proposal constitutes a second infradev csa dedicated to km3net the project will be carried out within the context of the current km3net collaboration which already has a provisional implementation of the management and governance of the research infrastructure in place the resources requested will be complemented by thecollaboration
making green audiovisuals sustainable

audiovisuals create impactful communication viewers retain 95 of a video message versus 10 for text brands that use video marketing experience revenues that grow 49 faster even this submission includes a videogreenvisuals supports thegreenshots entry in the market of producing sustainable commercials starting from its current offering for films and tv series i am vronique pevtschin ceo of thegreenshot part of a genderbalanced founding team 2 women 2 men thegreenshot has brought to market the 1st solution that accelerates the move to sustainable productions for films and tv series developed over 3 years how did we achieve that by thinking differently1 today carbon footprints are generated by accounting teams that start from financials they compute footprints from how much work costs we compute footprints starting from how work is done2 accounting teams compute carbon footprints after the facts we compute carbon footprints in realtime3 we also share granular carbon footprints in realtime with people on the field numbers relevant to individuals and teams empowering them to act4 we propose alternative solutions and providers directly inside our appour automations remove the additional costs of computing footprints and generate custom reports that facilitate certifications and esg reporting in 15 months thegreenshot has gained market traction with 10 clients in europe us and canada and professional recognition through 5 awards its team has grown from 4 to 18 people we have the innovative solution the team and the ambition this grant is ideally positioned in content and timing to help us enter a new yet accessible market structured around two phases creating the right business channels and preparing the optimal content for our next investment round greenvisuals helps thegreenshot reach its next growth milestone