Dragon09/odtu_chatbot huggingface dataset:
storage of electrons into chemical bonds towards molecular solar electrical batteries

while photovoltaics has observed rapid growth in the last decades and utilization of solar energy becomes ever growing part of the total electricity produced by mankind the lack of control over electrical output caused by fluctuation of solar irradiance is an inevitable drawback of the mass use of solar cells solar batteries addressing intermittent production of solar energy offer an elegant solution without the need of electricity transport and redistribution in most examples solar cells are combined with rechargeable batteries e g liion pb which increases the total weight and cost and leads to electricity losses the approaches for molecularbased storage of light energy solar thermal batteries exploit photoswitching molecules solar fuels that generate heat upon thermal back isomerization to this date no molecular approach for solar energy storage and subsequent direct generation of electric current exists because this requires development of lightactivatable molecules capable of hysteric electron storage and release solbatt develops molecular systems for transformation of light energy into chemical bonds and their subsequent transformation to electric current it uses fully organic redoxdriven molecular switches that reversibly form an electron storing bond upon redox process and combines them with suitable redoxactive partners that facilitate photoinduced electron transfer solbatt 1 improves our understanding of electron storage into chemical bonds and their subsequent release 2 delivers redoxresponsive molecular systems that can be charged or discharged upon external stimulus and 3 established design principles for photoactive redox materials suitable for the use in organic solar cells ultimately solbatt takes the vital step in finding a solution to a challenging issue combining organic solar cells with electron storage materials for solar electric batteries buffering the inherent fluctuations in solar electricity production
coherent raman histology and multiphoton imaging employing random illumination microscopy for the morphochemical analysis of brain tumors

central nervous system cns tumors encompass over 150 different types of tumors affecting the brain and spinal cord and can be categorized as primary or metastatic precise and rapid classification of these tumors is crucial to guide surgical decisions and plan personalized treatment strategiesalthough modern imaging techniques can determine whether a cns tumor is primary or metastatic surgical resection followed by intraoperative histological analysis is necessary to identify the specific tumor type traditional histology relying on the use of dyes is timeconsuming lacks chemical specificity and fails to provide a labelfree rapid and automated tool for cns tumor classificationchimera addresses these limitations providing cns tumor research with an imaging platform for intraoperative tumor diagnosis and classification that rapidly extracts spectral morphological and biochemical features of tumors in a labelfree way chimera will merge the sensitivity of nonlinear multiphoton techniques to endogenous biomarkers with the chemical specificity of vibrational imaging approaches using sumfrequency generation twophoton excited fluorescence and hyperspectral coherent antistokes raman scattering i will adopt a widefield random illumination microscopy scheme that provides superresolution in the transverse directions zsectioning capabilities reduced sample damage and unprecedented imaging speed over a large field of view through data processing and deeplearning classification methods chimera will offer a highly specific morphochemical contrast palette to simplify and accelerate the classification of various cns tumor types chimera will advance current nonlinear microscopy technologies unveil new insights for studying cns tumors and serve as a powerful diagnostic tool in biomedical research and clinical settings finally it will provide me with new knowledge in photonics biochemistry and data analysis to attain scientific independence
circular systemic solutions for plastic packaging biowaste and water

to contribute to catalyzing the transition towards a sustainable circular economcircsyst presents a series of shared demonstration experiences of new technological and societal adaptations to a circular economy involving 8 european regions valencia sp maribor si flanders be gotland sw paijathamelahti fi castila la mancha sp central macedonia el and central and east hungary huthe project focuses on three of the priority value chains of the circular economy plan water management biowaste and plastics and packaging as well as in the potential synergies among them4 demonstrators are proposed developing and validating solutions for water management1 reuse of industrial treated wastewater through ondemand treatment2 agricultural industry and utilities uses for reclaimed urban water3 smart wastewater management as a structural solution to water scarcity and floods in urban contexts4 validation of a set of integrated tools and methodologies for smart management of water symbiosisin the biowaste field the project will implement 2 demonstrators dealing with waste from different sources and extracting valuable substances directly applicable in the other addressed value chains5 flexible and intelligent biorefinery for the recovery of materials and components6 valorisation routes of food industry biowastesin the plastics and packaging field the project tackles main aspects of plastic waste management including ecodesign costeffective segregation and recyclability7 mechanical recycling of mpet8 consumers engagement in plastics segregation9 food packaging value chain redesign towards the substitution of plasticswork packages on communication dissemination knowledge transfer and results exploitation and impact are designed to ensure that that the results adequately reach key stakeholders in governments private organizations and civil society with the cooperation of the ccri coordination and support office
atmuspace interface and airspace reconfiguration service

this project aims to refine and complete the definition of the common atm uspace interface by identifying new working areas with impact and providing a consolidated interface with a standardized data model architecture and an operation method to achieve a minimum trl7 this proposal addresses the topic atm uspace interface and services which is composed of the following solutionssolution 1 atm uspace interface achieve full integration of atm and uspace systems by refining and completing the definition of the common atm uspace interface and identifying new working areas with impact on the already started common interfacesolution 2 dynamic airspace reconfiguration develop the complete service mentioned in uspace regulation and in their respective guidance material gm and acceptable means of compliance amc necessary to stablish the operating methodology and develop the standard interface to help atc actors in charge of airspace reconfigurations to maintain traffic segregation and to avoid proximity between manned and unmanned aircraft within the designated uspace airspace
actionable policies for adopting highquality integrated longterm care

longterm longterm care ltc services are intended for people who depend on help with daily living activities and who may also need permanent nursing care disability increases as we get older but can be found in all age groups the laurel project aims at gathering valuable insights into regional differences of integrated longterm care iltc provision and their support solutions in europe using this intelligence it will develop actionable policies to respond to the challenges of growing demand economic constraints accessibility affordability quality of services shortages of members of the workforce and systemic reformslaurel will identify a set of the best innovative integrated care solutions leading to better quality personcentred ltc and overcoming territorial and gender inequalities in their provision the project has the following six subobjectives1 develop a set of methods and tools for mapping and characterising iltc services in the eu27 covering availability and accessibility affordability reliability quality workforce funding governance autonomy and empowerment and supporting technologies and transversally incorporating the gender perspective and regional differences ruralurban gap2 undertake a field study in eu27 to identify the most successful innovative practices3 analyse the features of identified iltc services and contextdependent factors that provide insights into policies for the adoptiondevelopment of the best innovative practices including supporting technologies4 use this analysis to carry out qualitative research in the eu27 to generate a consensus on actionable policies favouring a shift to iltc by investigating the change management strategies that favour policy adoption5 produce a white paper on iltc that gathers together all the findings of the project and the consensually agreed actionable policies6 develop a set of training courses and tools to maximise the impact of the results
soft magnetoactive metamaterials for remote tunability of elastic waves

due to striking advantages such as rapid response and reversible change in the shape and properties under remotely applied magnetic fields soft magnetoactive materials have become an attractive material platform for humantechnology interfaces soft robotics actuators and sensors and biomedical devices however a systematic understanding of their dynamic behaviors in the extreme regime is still lacking creating a bottleneck to innovation and limiting their tremendous potential in nondestructive testing energy harvesting and smart soft wave devicesmetamagic aims at developing an experimentallyinformed framework to design and discover novel soft magnetoactive metamaterial systems with tunable and unusual elastic wave characteristics beyond the wavelength limit with a view to industrial applications in the design of smart wave manipulation devices the project proposes to exploit the unique transformative ability of soft magnetoactive materials integrated into the neat metamaterial design incorporating the local resonance and topological phase transition polar and asymmetric and nonlinear vector solitary effectsthe action mixes adhoc theoretical modelling with experimental tests and numerical simulations by fully leveraging the host and secondment institutions expertise and facilities and experience in scientific management the training programme is structured to strengthen my interdisciplinary skills and will allow me to grow as a worldclass leader in the emerging field of tunable and reconfigurable metamaterialsthe output of this action will open new levels of performance in a variety of advanced applications from broadband vibration isolation at challenging lowfrequency ranges to robust energy harvesting with ultrahigh transmission rates ultimately metamagic will advance the frontier of knowledge about reconfigurable soft metamaterials contributing to horizon europes policy and strategy in the key area of advanced materials
fluid biomarkers for neurodegenerative dementias

critical to our understanding of alzheimers disease ad and other neurodegenerative dementias ndds as well as to finding diseasemodifying therapies is the development of biomarkers for the underlying disease processes to facilitate improved diagnostics and drug discovery we have developed methods to measure markers of amyloid and tau pathology central and peripheral nervous system injury astrocytic and microglial activation as well as neuroinflammation our most exciting advancement in this field so far is the development of phosphorylated tau assays sensitive enough to measure this protein in plasma to detect ad pathology in the brain and to allow for disease stratification and monitoring based on ad pathology i now propose to develop new highthroughput biomarker tools that will enable the analysis of large cohort studies combining clinical imaging genetic and biomarker data to provide truly comprehensive molecular disease phenotypes that will inform interventions drug discovery and translational research clinical trial stratification detection of risk and resilience factors lifestylerelated as well as genetic and ultimately drive the quest towards clinically accessible personalised medicine in the ndd field a large part of the research efforts will be focused on discovering new biomarkers for tdp43 and synuclein pathologies nonad tau pathology and lysosomal and synaptic dysfunction through general and targeted proteomics on csf samples and through employing a novel cell typebiased tandem mass tag proteomics workflow to discover biomarkers related to neuronal astrocytic and microglial cells and their different activation states promising csf biomarkers will be examined in blood biomarker candidates that are measurable in this matrix and correlate with csf will be developed into sensitive and specific blood tests using cuttingedge technology as we have previously done for a40 a42 ttau ptau nfl and gfap
elucidating the superior colliculusrelated network properties and modulation in huntingtons disease mouse model to delay the onset and ameliorate severity of the motor symptoms

neurodegenerative movement disorders eg huntingtons disease hd predominantly involve progressive motor symptoms as a result of disrupted basal ganglia neuronal networks these symptoms are accompanied by early occurring deficits in visual perception and oculomotor functions which share neuronal circuits with motor domains and can be used in the prediction of the onset and severity of hd pathogenesis therefore understanding the early circuitry alterations in hd progression is crucial to develop new diseasemodifying strategies the superior colliculus sc is a sensorimotor structure that receives and integrates visual information to control reflexes and is involved in visual perception and oculomotor functions functional mri and behavioural studies demonstrated that the hd symptomatic mouse model show alterations in the sc function but its role in motor symptoms has not been directly addressed the hdsc project proposes that i sc is an important factor in the basal ganglia circuit alterations found in hd ii topographically segregated sc outputs provide differential contributions to the motor and defensive behaviours and iii temporal control of sc neuronal plasticity with novel phytochromes will cause delay and amelioration in motor symptoms in hd model this will be addressed using a combination of mouse behavioural histological and biochemical phenotyping to reveal the onset of screlated alterations in the hd model then by using dreadds we will determine the differential representation of sc outputs in motor and defensive behaviour finally we will test the capability of phytochromes to modulate sc neuronal plasticity and delay and ameliorate motor symptoms in the hd model overall the hdsc aims at bringing a spotlight to mechanisms causing symptomatic resilience in the hd model which potentially could be implemented in other neurodegenerative movement disorders with basal ganglia circuit alterations
effect of network of different grain boundaries and triple junctions on sensitivity of microstructures to hydrogen embrittlement

a network of grain boundaries gbs and a microstructure which is less sensitive to hydrogen embrittlement using grain boundary engineering will be assessed on multiple scales the fabrication of bi and tri crystals with a great variability of grains misorientations according to the probability of their presence polycrystalline nickel and nickelbased superalloys will be done the hydrogengbs and hydrogen triple junctions tjs interactions will be examined for different configurations of nickel bicrystal and tricrystals systems having variety of grain boundary energy vacancy concentration and excess volume finally influence of hydrogen on gbs and tjs will be characterized by diffusivity trapping or segregation energies and cohesive energies the atomistic level investigation will be done to understand the fundamentals of hydrogen embrittlement of gbs and tjs having same orientation as of fabricated crystals the bi and tricrystals will be modelled in molecular dynamics code using lammps software for understanding at atomistic level a 3d polycrystalline fem model will be reconstructed and these simulations should provide the optimum solutions for the architecture of the gbs and tjs networks to obtain the less sensitive microstructures to hydrogen embrittlement
a holistic framework with anticounterfeit and intelligencebased technologies that will assist food chain stakeholders in rapidly identifying and preventing the spread of fraudulent practices

watson provides a methodological framework combined with a set of tools and systems that can detect and prevent fraudulent activities throughout the whole food chain thus accelerating the deployment of transparency solutions in the eu food systems the proposed framework will improve sustainability of food chains by increasing food safety and reducing food fraud through systemic innovations that a increase transparency in food supply chains through improved trackandtrace mechanisms containing accurate timerelevant and untampered information for the food product throughout its whole journey b equip authorities and policy makers with data knowledge and insights in order to have the complete situational awareness of the food chain and c raise the consumer awareness on food safety and value leading to the adoption of healthier lifestyles and the development of sustainable food ecosystems watson implements an intelligencebased risk calculation approach to address the phenomenon of food fraud in a holistic way the project includes three distinct pillars namely a the identification of data gaps in the food chain b the provision of methods processes and tools to detect and counter food fraud and c the effective cross border collaboration of public authorities through accurate and trustworthy information sharing watson will rely upon emerging technologies ai iot dlt etc enabling transparency within supply chains through the development of a rigorous traceability regime and novel tools for rapid noninvasive onthespot analysis of food products the results will be demonstrated in 6 use cases a prevention of counterfeit alcoholic beverages b preservation of the authenticity of pgi honey c onsite authenticity check and traceability of olive oil d the identification of possible manipulations at all stages of the meat chain e the improved traceability of highvalue products in cereal and dairy chain f combat of salmon counterfeiting
steam for home economics and research exchange

steam for home economics and research exchange sharee aims to develop a europeanscale research and innovation based hub at tallinn university science kitchen with a sustainable management and research performance strong networking and finance generation capacity to become an independent and internationally recognised actor in the field of home economics science kitchen will be a new product a new environment that unites classroom kitchen and lab science kitchen bridges various disciplines through collaboration and initiates dialogues between stakeholders for the benefit of wider society in the context of eg climate public health and educational challenges thereby science kitchen helps to upcycle the home economics area in estonia and develop the awareness and the use of its results to tackle several international modern challenges steam is a corner stone for interdisciplinary collaboration inside and above the boarders of tallinn university in sharee home economics implementation in the eu countries will be mapped and connected with steam subjects to give policy recommendations for home economics education various disciplines are invited to codesign interdisciplinary science kitchen activities this twinning provides the capacity to create new and impactful research and innovation in the field of home economics sharee enables to advance the quality and volume of home economics research in estonia and the eu in cooperation with the international project partners and increase the impact of the research locally nationally and internationally with a specific focus on the policy relevance of the research ideas so far mainly feminine subject area advantages through sharee as steam fosters gender equality by uniting experts and researchers from various disciplines the interdisciplinary experience in sharee will be analysed and recommendations will be put together for working across disciplines
arctic seaice reconstructions using ancientdna

the arctic seaice is an important ecosystem that guarantees food security and plays a key role in the regulation of the global climate affecting the livelihoods of people beyond the arctic region the arctic seaice is shrinking and studies predict an arctic seaice free summer by 2050 the impacts of a seaice free arctic on the climate system and human activities are little understood mainly due to the limited availability of tools to reconstruct and understand the arctic seaice history stateoftheart sedimentary ancient dna sedadna analyses offer novel solutions to better understand seaice ecosystems arctistic proposes to i design and test novel molecular tools ddpcr assays to trace seaice associated taxa in marine sediments ii validate the new ddpcr proxies against established tools for seaice reconstruction lipid biomarkers and iii assess the impact of seaice changes on biodiversity using metabarcoding analysis on the same sediment samples and bioinformatics arctistic research activities will deliver a novel and innovative toolbox for seaice reconstructions tools and data will be made available in open access publications with the aim to accelerate arctic seaice reconstructions beyond arctistic arctistic presents an excellent opportunity for the exchange of the latest skills and approaches for seaice reconstruction between myself and norce norway with a secondment at awi germany arctistic will allow me to develop new skills in sedadna methods palaeoceanographic proxy development and bioinformatics expand my research network and gain a stronger understanding of arctic ecosystems and seaice history i will also develop transferrable skills in science communication and project management to ensure a future career path as an independent researcher