Dragon09/odtu_chatbot huggingface dataset:
food quality control by rna profiling foodrna

the field of food quality control is important to all consumers ensuring food safety and detecting food substitutions and fraud nextgeneration sequencing has the potential to revolutionize the field but practical solutions are lagging behind stateoftheart dnabased tests yield limited information beyond what animal plant and bacterial species constitute a given food product and in some cases performing that task suboptimally profiling rna in food products can potentially yield important novel information that dnabased tests cannot including expression information that can be used to ensure food safety and quality and detect food fraud with a focus on plantbased food products we will develop optimize and set up tests that will be substantially cheaper and more sensitive than the stateoftheart allowing upscaling in food quality control we will provide our product as a service to national food control agencies which we already collaborate with and also to highend food producers as an accreditation service we foresee that as consumer awareness increases the demand for these tests will increase exponentially in the future
chemical conversion of a sustainable aviation fuel saf pcymene

the aviation industry is one of the largest consumers of fossil fuels and therefore a high emitter of co2 and fine particles which can contribute to the formation of contrails and can have adsorbed the carcinogenic polycyclic aromatic hydrocarbons pahs emissions from this sector are expected to increase more and more due to its rapid growth to address this problem the use of alternative fuels from renewable biomass and waste resources such as sustainable aviation fuels safs has been receiving increasing attention sustainable aviation is the goal of eu due to its need to reduce transport emissions by 90 by 2050 compared to 1990 levels suitability and validity of safs need to be evaluated prior to use in enginesturbines and it can be done with highquality experimental data in conjunction with chemical kinetic models which is a valuable tool to investigate reaction pathways and to guide fuel and engine design however there is a lack of experimental data obtained at laboratoryscale and chemical kinetic models describing the combustion of safs thus this project aims to provide new experimental data and a kinetic model for the conversion of pcymene an aromatic terpenoid produced using several natural feedstocks in order to contribute with the comprehensive understanding of its combustion behavior and its capacity to form fine particle and pahs the experiments will be conducted under a wide range of operational conditions of interest for combustion using the facilities and equipment available at the aragon institute of engineering research i3a of the university of zaragoza chemcon will be conducted in the multidisciplinary thermochemical processes group gpt with the guidance of prof mara u alzueta expert in the field of minimizing pollutant emissions in combustion processes this project will strengthen my skills and independence expanding my professional network and allowing me to establish my own research line and laboratory
transport research arena 2024 dublin

this proposal describes a series of activities that will support the successful delivery of the tra conference in dublin in 2024 a consortium has been assembled that addresses all the key requirements of the callthey represent the key transport modes with at least 2 partners active in road rail waterborne aviation and crossmodalthe partners are all active in european research and have the reach to promote the conference across europethe partners have a long history of delivering high quality researcher competitions where europes research leaders are recognised the partners will work with key stakeholders to ensure the conference themes support european policies the proposal also has the full support of the irish minister for transport and this will ensure the full support of relevant irish agenciesthe partners will work together to deliver a conference that builds on the success of previous tra conferences and provide a forum that will allow the key actors in the transport sector come together to develop solutions for societys needs
designing the irresistible circular society

designing an irresistible circular society desire aims to create an alternative way forward for the built environment supporting the eu mission of 100 climateneutral and smart cities against seemingly insurmountable challenges of climate change biodiversity loss and resource depletion we need to rethink our approach to finding solutions departing from architecture design and art we will create an open learning environment with principles methods and guidelines to support us in designing an irresistible circular society we will present a desire lighthouse demonstrator built on insights and learnings from onsite demonstration activities taking place on sites in denmark italy latvia slovenia and the netherlands encompassing various themes and scales by this we will set the foundation for a school of thought and practice and establish a scaling framework for widespread learning across the eu utilizing digital infrastructure stakeholder involvement and empowerment across a partner community of european cities youth organisations ngos academia etc our territorial sites form the core of desire three themes have informed our choice of sites and partners creating social and inclusive housing addresses the need for inclusive processes the power of we in circular transformation of social housing reconciling cities with nature is about designing livable habitats and functional ecosystems from a multispecies perspective while rebalancing land use to accommodate resource generation and biodiversity transforming through symbiotic relationships focuses on how to optimize use of materials flow when rethinking urban landscapes in cities in depts onsite demonstration activities will unfold in three danish sites an old asphalt factory in herlev a social housing neighbourhood in taastrup and an urban transformation project in kalundborg and contribute to similar demonstration activities in amsterdam ljubljana milan riga and turin
an integral solution for quantifying intracellular lipid transport using close to native lipid probes

dysregulation of lipid transport and metabolism is at the center of many diseases despite its crucial role gaining a full understanding of lipid transport remains challenging as visualizing lipids and their transport by microscopy is almost impossible by providing technological solutions to this problem we envision to enable new therapeutic strategies with the corresponding benefits for society at large a better understanding of lipid transport can help guide the design of drugs to for example treat fatty liver disease which is estimated to affect up to quarter of the global population during the erc poc grant period we plan to translate our current protocols to high throughput screening setups with the goal to service the pharmaceutical industry and design readytouse kits and devices that will allow academic laboratories to answer their unique research questions
electronic didactic and innovative platform for learning based on multimedia assets

distance learning has become a great ally in the current pandemic situation the ediploma project will establish the elearning in an upper quality level in a three years research project posing the use of augmented realityvirtual reality artificial intelligence machine learningdeep learning interactive technologies chatbots and gamification in a newly designed elearning platform this project will use techniques and technologies previously proven successfully in the broadcasting gaming and esports industries they will be adapted to the educational world developing innovative learning practices a cocreation methodology will be used to include the main educational actors teachers educators pupils families course providers and policy makers and their social relationships inclusiveness accessibility and sustainability will also be taken into account this project states that knowing the potential opportunities barriers accessibility and risks of use of emerging technologies for teaching and learning in educational practices including necessary innovation skills for teachers will support their digital transformation and will contribute to understanding the social ethical political and economic impacts of digital practices and in addition it will increase the resilience of the educational world accepting the benefits of this digital change as well this project will consider the needs for an adequate teacher training in relation with new educational technologies analyzing the shifting role of teachers trainers and educational leaders in the digital transition affecting education and training as well as their training needs including digital and leadership skills required in an emerging society of permanent and quick technological change
neural encoding of wetness perception in the cortex

perception depends on the representation of external information in the cortex this information enters the nervous system thanks to receptor proteins in your sensory neurons these receptors transform external energy into neural activity it follows that if you do not have receptors sensitive to an environmental property you cannot perceive such property for example humans are not able to sense electric fields whereas some fish can because they have electroreceptorsa sense required for survival is wetness due to its role in thermoregulatory responses unlike insects humans lack hygroreceptors sensitive to the level of moisture of the skin yet we have clear sensations of wetness so how do we feel wetness researchers think that these sensations emerge from the integration of thermotactile signals in the cortex but the location or cellular encoding of wetness in the cortex is unknown therefore i propose to study the neural basis of wetness sensations in mice the mouse is an ideal mammalian model for this because their thermotactile system is similar to ours and tools to measure neuronal activity can be combined with behaviour crucially researchers have recently found a colocalised representation of thermotactile stimuli in the mouse cortexfirst i will develop wet stimulators for use in mice based on designs from human studies second i will measure wetness sensations in mice by developing a novel perceptual task third i will use calcium imaging techniques to identify and study cortical neurons activated during wetness sensations finally i will use optogenetics to provide a causal relationship between neural activity and wetness sensations this project will advance our understanding of how wetness sensations emerge through cortical activity even in the absence of a wetness receptor the research output will advance our understanding of brain function but also will be of interest to the clothing cosmetic and virtual reality industries
language ecology and modality in turntaking acquisition

the acquisition of turntaking is pivotal to a childs pragmatic development learning how and when to contribute and align with your interlocutor is a critical skill that enables smooth conversation despite extensive research on the development of turntaking in spoken languages we know little about how this unfolds in sign languages differences are likely as deaf children usually lack rich language models ecology and the visualspatial nature of sign languages poses different challenges to manage visual attention modality to address this gap this project investigates turntaking development in an exceptional context a balinese village characterized by high incidence of deafness and widespread use of the local sign language kata kolok here children acquire kata kolok surrounded by a village of signing adults providing an unparalleled opportunity to study how signingrich ecologies shape turntaking development in the visuospatial modality i conduct two complementary studies first i follow the developmental trajectory of turntaking of deaf children across 14 years comparing their practices to turntaking practices used by the adult signers in their community for this i draw on a unique interactive corpus of longitudinal naturalistic recordings of children who acquire kata kolok from their deaf caregivers from birth kkcsc and use a microlevel analysis of spontaneous conversations second i use an experimental spotthedifference task to further tease apart how conversational setting affects turntaking examining whether age of conversation partners child vs adult and number of interlocutors two vs three or more affect turntaking behaviour among adult and child kata kolok signers merging threads from social interaction sign language linguistics and language acquisition the letitia project represents a paradigm shift in the study of sign language acquisition grounding linguistic observations and analyses in realworld language use
selforganising principles underlying nanodomain formation and function

signal transduction of diverse inputs often relies on a comparatively small number of central signal integrators the resulting question how such a central signal transmission protein can recognise the specific input and trigger the respective appropriate outputs is as of yet unresolved however recent research focusing on plant signal transduction suggested that the precise spatiotemporal organisation and the organisation of signalling modules into membrane nanodomains could play a crucial role in achieving signal specificity a prime example in arabidopsis is the gtpase rho of plants rop6 that forms nanodomains in the auxinmediated gravitropic response as well as in osmotic stress in sona i will use rop6 as model system for membrane organisation at the nanoscale to dissect the selforganising principles of nanodomain formation and function my host group and collaborators discovered how rop6 assembles into nanodomains which will be the foundation for a detailed and innovative characterisation of how proteinlipid interplay contributes to nanodomain specificity based on preliminary results i will use live superresolution microscopy to investigate how and where rop6 nanodomains are nucleated after auxin and hyperosmotic treatment respectively in addition i have two parallel complementing goals in identifying the membrane lipids necessary for sustaining the nanodomains and the protein components required for feedback loops and specificity in rop6 nanodomain signalling taken together sona will give insights into the membrane organisation of rop6 nanodomains at unprecedented spatiotemporal resolution it will also challenge our understanding of the signal transduction at the plasma membrane by emphasising how selforganising principles contribute to the formation of specific signalling modules finally this action will provide me with valuable training to develop into an independent researcher in the field of plant lipid and membrane research
transforming europe through doctoral talent and skills recognition

doctalent4eu aims to enhance phd employability through a strong visible and innovative recognitionsystem of the most indemand transferable skills relying on the esco framework that earlycareer researchers ecrs acquire or will acquire through their doctoral training and research activities the consortium will adopt a multiactor approach involving nonacademic stakeholders eg public authorities industries or business to improve transferable skills training and to develop local talent management centers the project will also develop a new prototype based on machine learning to support esco in continuously updating and predicting the most indemand skills on the labour market concerning the 8 eqf level according to the expected skills from job offer collections
preventing noncommunicable diseases caused by the postacute phase of covid19 infection

the postacute phase pap of covid19 occurring 4 months after the acute phase is associated with an increased risk for the development of noncommunicable diseases ncds the risk of complications in this phase does not depend on the severity of the acute phase in the eu more than 183 million cases of covid19 have been reported and up to 70 of patients suffer reduced organ function in the pap our conservative estimate it that 5 of people who have suffered covid19 are at risk of developing ncds of the pulmonary cardiovascular and renal systems due to the papto avoid the significant socioeconomic costs related to this burden point will develop knowledgebased biomarkers for prevention and management of ncds a virtual twin model that offers clinical decision support and clinical guidelines and recommendations for the entire health care value chain with special attention to vulnerable groups we will fulfil an unmet need for knowledge and tools to minimize the risk factors of the pap at the optimal point in time when healthcare systems will have to redirect their focus from the acute phase of covid19 to the postacute phase the outcomes of point will aid the health care value chain already from an early phase of the project furthermore point will correlate and promote knowledge on the development of ncds in general and the risks of pap from other infectious diseasespoint will meet the challenges with a holistic approach from a truly interdisciplinary consortium consisting of clinical experts molecular biologists behavioural scientists and computer scientists who will take advantage of cohorts of more than 6 million europeans and crosssectional biobanks from more than 6000 europeans researchers will work together with standardisation experts an enduser organization representing 120000 physicians as well as a dedicated partner for data management ensuring rapid absorption of the outcomes of the project by all stakeholders
advancing holistic understanding of community resilience and heritage drivers through communitybased methodologies

resiliages mission is to provide novel knowledge and impactful solutions for exploiting europes hidden and unused resource community resilience resiliage will enable a stepchange in disaster risk management and in the way research and practice deal with variation in aspects of society like culture risk awareness inclusion socioeconomic and geographical conditions by cocreating resilient communities through digital tools and soft solutions consolidated in a holistic and systemic approach resiliage aims to improve understanding of the behaviour and psychological reactions of diverse society groups affected by a natural and manmade disaster and enhance community resilience indeed with the proactive and participatory involvement of all the relevant stakeholders and end users resiliage will coshape and develop a set of digital tools and soft solutions to support first responders and public authorities empower citizens share more accurate and accessible information prior during and after a natural and manmade disaster or crisis situation these will be integrated in a digital platform the resource ecosystem for community resilience and validated through a holistic systemic disaster risk management and multihazards approach in five community resilience labs and their networks results and lessons learned will provide guidelines and policy recommendations to enhance preparedness plans sendai framework and strategies for climate change adaptation
aligning brain rhythms understanding the mechanisms of cortical tracking of speech to improve language functions with real time closedloop neurofeedback

speech processing and reading are essential unique human abilities underpinning social educational and professional advancement however early biomarkers for learning disabilities such as developmental dyslexia dd and for second language learning have yet to be identified here cutting edge neuroimaging tools carefully designed tasks and longitudinal designs will be used to record cortical tracking of speech cts namely the temporal alignment between fluctuations in the speech signal and fluctuations in electrical brain activity across different populations specifically we will investigate the predictive ability and causality of cts 1 at an early age in language development 2 for second language learning reading dd and illiteracy 3 establish the domainspecificity of cts as biomarker of language processing and 4 pioneer a realtime closedloop neurofeedback protocol modulating cts to adaptively change language processing and learning through neurofeedback this project represents a radically new scientific approach that will break new ground by investigating the predictive ability of cts that combined with longitudinal designs and realtime closedloop neurofeedback will allow us to 1 establish causal relationships and 2 use this novel approach to improve l2 learning and to diagnose and remediate dd
regenerative icos tokenizing debt and dividends

the economic incentive structures of an organisation strongly influences their governance models power distribution sometimes to the extent that attempts at decentralising governance fail if they are built on centralising economic incentives traditional forms of equity investing offer uncapped returns to shareholders that create strong incentives for profit maximisation and centralisation of power initial coin offerings icos on the blockchain were designed to allow organisations to raise funding from their community and bring a greater distribution of economic gains and governance power to organisations stakeholders however since tokens issued through icos are also offering uncapped returns current blockchain networks have become even more centralised there are investor reward models in traditional forms of investing that cap stakeholder profits and through that remove the incentives for profit maximisation like platform cooperatives and steward ownership companies they have shown to bring greater distribution of economic gains and governance powerhowever those organisations struggle to raise early stage funding in the traditional financial market a consumer investors conscious about the damaging effects of investing in uncapped public equity have challenges investing in such organisations this is because capped investor profit models have only been implemented in the existing legal systems with significant bureaucratic hurdles similar to traditional startup investing up until the advent of icos in the late 2010sthis proofofconcept helps organisations to run initial coin offerings with capped investor profit models so they can raise funding from a diverse set of supporters while avoiding mission drift and profit maximisation incentives it enables more economic decentralisation transparency and accountability from which decentralised organisational governance can be developed and maintained in a more sustainable way
an innovative onchip multisensing platform for singleuse biopharmaceutical applications

the growth of biomanufacturing characterised by an everincreasing number of bioproduced molecules including lifesaving drugs is hampered by high bioprocessing failure rates that incur over 2 billion in annual losses for companies like johnson johnson it is also associated with significant environmental impacts particularly in sterilisation processes singleuse technologies have emergedas a solution yet they require advanced sensing capabilities for full effectiveness inspek addresses this need with its multisensoron achip technology utilising waveguideenhanced raman spectroscopy wers and photonic integrated circuits pic our picsintegrate essential bioprocessing sensors raman spectroscopy temperature ph dissolved oxygen and others into a single compact platform inspeks noninvasive technology outperforms traditional sensors in cost and efficiency enhancing realtime bioprocess monitoring and reducing the development time for new biotherapies