Dragon09/odtu_chatbot huggingface dataset:
investment and eu law reconceptualizing reverse discrimination

the rulierd project aims to reconceptualise the hierarchy of norms of the european legal order to lessen the clash between european union eu law and international investment law to achieve this aim the project examines reverse discrimination rd as an understudied and yet representative issue of this larger phenomenon following the achmea case of 2018 the court of justice of the eu has progressively developed a farreaching interpretation of the principle of autonomy of the european legal order that renders difficult the coordination of eu law with international investment law at a theoretical level rulierd will be the first research project to explain the connection between the dualistic attitude of the court of justice of the eu and rd at a practical level it is unclear whether rd is admissible under article 18 of the treaty on the functioning of the eu or under general international law rd may in fact endanger the principles of equality and fair competition if foreign firms are treated more favourably than domestic firms this disadvantages small domestic companies thus adversely affecting economic development rulierd examines the practical and theoretical aspects of rd using an innovative combined methodology that involves the use of law and economics market power theory allows defining rd and testing whether rd jeopardises the fair functioning of the common market the hypothesis is that a neomonist approach could avoid rd rulierd makes both a theoretical and practical contribution it mitigates the clash between eu law and international investment law and identifies a fairer legal framework for companies operating in the eu market
inspiring creativity investigating how a digital arts intervention can enhance creative mindwandering

mindwandering research in the cognitive sciences shows that a significant portion of novel ideas and breakthrough aha moments happen when attention is shifted internally away from tasks in the external environment however research has not explored how to encourage these creative mental wanders inspired by how exposure to art leads to generating innovative ideas this project investigates the hypothesis that a digital arts intervention can enhance creative thoughts when mindwandering this use of digital technology is antithetical to its common aim of guiding attention externally accordingly this project challenges how we use digital technology and opens opportunities for interdisciplinary research across the arts and sciences expected impacts are 1 paving a new direction in mindwandering research by investigating the possibility of inspiring creative thoughts 2 uncovering how digital arts can be an empirical tool to investigate cognitive processes and 3 conceptually extending the discourse of how technology affects cognition this project will produce highimpact research publications presentations and an interdisciplinary symposium to disseminate findings across relevant disciplines communication with the public will be facilitated with a project dedicated website and targeted outreach efforts both at the tc and return host institutions
advancing scientific collaboration in phage therapy for treating pseudomonas aeruginosa and staphylococcus aureus

asclepiuss overall aim is to boost the scientific excellence and innovation capacity of giorgi eliava institute of bacteriophagy microbiology and virology eliava and its highquality twinning partners linstitut national de recherche pour lagriculture lalimentation et lenvironnement universidade do minho and intelligentsia consultants sarl to expand their insights in phage therapy for treating pseudomonas aeruginosa and staphylococcus aureus to achieve this aim asclepius will implement a research and innovation strategy over three years based upon five objectivesobjective 1 conduct exploratory research on phage therapy for treating pseudomonas aeruginosa and staphylococcus aureusobjective 2 transfer knowledge between experienced researchers of eliava and the twinning partnersobjective 3 enhance career prospects of earlystage researchers of eliava and the twinning partnersobjective 4 improve eliavas management and administrative capacity for european rd programmesobjective 5 raise the research profile of eliava and the twinning partners
advanced hybrid solar plant with pcm storage solutions in sco2 cycles

hybridplusadvanced hybrid solar plant with pcm storage solutions in sco2 cycles hybridplus aims to pioneer the next generation of csp with an advanced innovative highdensity and hightemperature thermal energy storage tes system capable of providing a high degree of dispatchability at low cost and with much lower environmental burden than the state of the art this thermal storage is based in the phase change material pcm technology in a cascade configuration that can reproduce the effect of a thermocline and integrates recycled metal wool in its nucleus that provide hybridization possibilities by acting as an electric heater transforming nondispatchable renewable electricity such as pv into thermal stored energy ready to be dispatched when needed hybridplus proposes a novel approach to concentrated solar power with a pvcascade pcmtes csp configuration based on a high temperature supercritical co2 cycle working at 600 c this new plant is called to form the backbone of the coming energy system thanks to a higher efficiency and lower lcoe than stateoftheart technology and in addition to other benefits such as full dispatchability reached with the hybridization in the storage that allow higher shares of variable output renewables in the energy system and environmental friendliness lower co2 emissions minimum water consumption enhancement life cycle impact
chemistry informed machine learning in emulsion polymerization processes and products

machine learning ml systems continue to revolutionize many aspects of daily life but despite their immense potential have yet to impact significantly in polymer science one major issue that is hindering the more widespread use of machine learning in polymer science and many other physical sciences lies in the challenges in amassing sufficient data to efficiently train machine learning models this in itself is not necessarily a problem and is an issue frequently encountered in the machine learning field but can only be resolved by a thorough understanding of the science behind the problem of interest cinema aims to providing a training platform that will allow the next generation of polymer scientists to take polymer science into the 21st century through incorporating the fundamental knowledge gained over many years of research into the training of machine learning systems such a knowledgedriven machine learning approach puts the scientific issues of cinema at the forefront of the use of machine learning in fundamental scientific problems and also provides the perfect training platform for the next generation of scientists for whom the use of ai will be an invaluable tool
lipid inclusions modulating inflammation in thrombotic stroke

each year 11 million inhabitants of europe suffer stroke stroke leads to extensive neuronal loss and results in an environment filled with cellular debris notably myelin debris the clearance of this debris by microglia is crucial for restoring homeostasis but it can overwhelm their phagocytic function consequently damaged areas often exhibit microglia with cytoplasmic inclusions known as lipid droplets lds recent findings by one of the supervisors indicate that microglia in young mice accumulate lds with plin2 being one of the most differentially expressed genes after brain ischemialimits aims to characterize the contribution of lds to the neurological deficits following thrombotic stroke to be exploited as i novel markers for monitoring and ii novel therapeutic targets additionally we will develop new preclinical models to share with the entire research communitythe objectives are i to establish a new strain of transgenic mice with a deletion of the plin2 gene in microglia ii to characterize the inflammatory response lesion volume and neurological function after ischemic stroke of this new strain and iii to identify new pharmacological approaches targeting lds for the treatment of ischemic stroke my expertise in inflammation and metabolic reprogramming the supervisors established proficiency in clinical and basic stroke research the lipid expertise of our collaborators and the availability of all necessary facilities and training opportunities at the host institution will ensure the success of this researchlimits project has the potential to uncover innovative therapies for ischemic stroke furthermore since lds have been shown to play a pivotal role not only in ischemic stroke but also in other conditions such as aging obesity and cancer the results from this project are expected to have a significant impact across various disease areas
insitu fetoscopic 3d bioprinting for spina bifida treatment

currently available prebirth surgical treatments for spina bifida aperta sba still do not provide a complete recovery in babies and would potentially benefit from a tissue engineering approach indeed the first clinical trial using stem cells for sba has recently started however this is performed via an openuterus approach this made me wonder what if we can develop an innovative system to deliver via fetoscopy a bioprinted tissue engineering costructfor sba repair such an approach would promote tissue regeneration and ease the surgeryin 3dfetoprint i will develop a system for the insitu fetoscopic bioprinting of a gel composed of extracellular matrix ecm proteins and amniotic fluid stem cells afscs to close the defect of spina bifida aperta sba in a large animal modelthe project will be divided into three work packages first work package will address the development and testing of the gel by studying the interaction between fetal ecm proteins and afscs to define a gel formulation that could be bioprinted inutero second work package will focus on the design and development of an innovative fetoscopic bioprinting device capable of bioprinting a gel patch on the fetus last work package will finally validate the innovative approach we will first validate through invitro testing using a laparoscopic simulator then we will perform a sheep spina bifida aperta model where the innovative fetoscopic 3d bioprinting system will be vaildatedwe will leverage my expertise in biomaterials cells and tissue engineering device design to carry out this project that will deliver a revolutionary system that will open up the possibility to bioprint tissue engineered constructs on the fetus
devising reliable electronic structure schemes through eclectic design

modern quantum chemistry reached a remarkable level of description of atoms and molecules and their interactions theoretical approaches are particularly helpful when experimental studies are hampered or slowed down due to a trialanderror approach in such cases computational chemistry can provide the much soughtafter understanding of molecular properties and reactivity unfortunately conventional wave function models are too expensive for largescale modeling or require user control on an expert level while density functional theory may predict unreliable properties to break the current paradigm of computational chemistry novel and neat approximations are desirable one such innovative approach models manyelectron systems using electron pair states current electronpair methods are however insufficient to reach chemical or spectroscopic accuracy for large molecules of organic electronics and must be extended to i accurately describe electron correlations beyond the simple electronpairing effects especially in cases where conventional corrections break ii reliably predict molecular properties of both ground and electronically excited states of closed and openshell compounds and iii provide an intuitive and blackbox platform for nonexpert users these goals will be achieved by a dressing electronpair states with information extracted from multireference wave functions using a bottomup approach where each step systematically improves the accuracy of the previous model along the ladder of approximation b designing a blackbox interface to automatized quantum chemistry calculations using concepts of quantum information theory and c elucidating the structureproperties relationship using the picture of interacting orbitals the synergy between an inexpensive but reliable quantitative description and the qualitative interpretation of molecular interactions will accelerate the discovery of new materials in organic electronics
euciembly creating an inclusive european citizens assembly

eu ciembly addresses the need for the introduction of new forms of citizens participation and deliberation in eu political life and particularly an eu citizens assembly whose design and implementation fully addresses issues of intersectionality inclusiveness and equality while there has been an admirable appetite to improve the landscape of participatory and deliberative democratic mechanisms at the eu level this has not always been accompanied by adequate considerations of how to build these mechanisms to ensure avoidance of intersectional discrimination and the exclusion of vulnerable groups of citizens in fact the concept of intersectionality within eu law has presented difficulties even without bringing into the picture the context of citizens democratic participation the time is ripe to create a new participatory tool with intersectionality at the forefront this project will provide the analytical framework and the prototype through which such a tool can be created in the form of a citizens assembly that can be established at the eu level and with features allowing for the transfer of a modified prototype to the national and local levels of eu member states to do this the project moves from theorising to evaluating and finally piloting such a tool and concludes with recommendations in this way euciembly seeks to be the first project that uses an academic and theoretical understanding of issues of intersectionality equality and power relations in the design of an innovative and inclusive eu citizens assembly
ilimited firstever ionic liquid sorbent methanol synthesis in order to enable over 80 yield

ilimited proposal targets the firstever ionic liquid sorbent methanol synthesis enabling over 80 yield production thanks to a high selective encapsulation technology for creating an unique longterm energy storage integrated process due to the decentralized conversion of co2 sources through an accurate 3dprinting reactor technologyilimited proposes a breakthrough integrated system that encompass several key technological advances ktas kta1 high selective thermocatalytic methanol synthesis reaction system through insitu product removal by ionic liquid able to increase current soa maximum yield 60 to over 80 kta2 catalyst encapsulation for the fouling and poison prevention of the cuznoal2o3 catalyst will allow the gas to diffuse over the catalyst while avoiding direct contact with ionic liquid leading to a efficient and stable operation of methanol synthesis and kta3 a 3dprinted fluid guiding reactor able rise up to 515 the total conversion in the reactor circumventing the thermodynamic limitations thanks to the maximization of the fluid contact through the above the soa microchannels adhoc designed for the reactor based on advantages the technology has an upper hand against the conventional methods also in utilizing local small scale co2 sources avoiding high heat exchange duty and allowing operation at lower pressures ilimited targets the use of this technology in wwtp as possible future biorefineries enabling longterm energy storage and fuel production while providing a source of methanol for use in denitrification by utilizing carbon dioxide from biogas the potential for energy storage is enormous as the anaerobic digestion ad sector grows with 21 million tons of co2 per year from ad sources available by 2030 the readily available energy from produced emethanol is estimated to be over 65 twh which is a large contribution to a stable energy supply compared to the average monthly electricity consumption 220 twh
lightreconfigurable substrate for cell cultures

lcell is a method for robust reconfigurable control of surface topography based on creating reversible lightinduced surface structures onto azobenzenecontaining bilayers these lightreconfigurable substrates allow freeform topographical patterns to be created and subsequently erased over many cycles on a biocompatible cell culture substrate even when the cells are already growing on the substrate lcell aims at mimicking more closely the dynamic conditions in human body which regulate many physiological and pathological processes such as tissue morphogenesis healing and tumour growth our noninvasive solution is important for definition of chronoprogrammes eg cell differentiation stem cell phenotype harvesting tissue regeneration and triggering cell directional migration the bilayer structure allows for easy chemical modification of the surface ensuring biocompatibility and further functionalization and fully supporting existing protein deposition techniques lcell reconfigurable lightresponsive petri dishes can be used as dropin solution enabling new unique biological investigations on cell dynamics to be conducted besides the growing need to reduce animal testing in drug screening toxicology and research has increased the demand for innovative cell culture solutions that recapitulate the complexity of cell dynamics in a controllable costeffective way without sacrificing their clinical relevance for all these reasons lcell offers new opportunities as an innovative tool for a wealth of potential targets
barium in the southern ocean indian sector

barium ba has been proven to be a particular useful tool to estimate organic carbon remineralization in various areas of the worlds ocean to date however the ba cycle and its budgets in the ocean are not well constrained indeed in the ocean sources of ba from hydrothermal alteration and deepsea sediments but also the internal ba cycle are hard to constrain with ba concentrations alone the use of ba isotopic composition 138ba measurements can provide meaningful insights on these sources and processes specifically different inputs and different biological processes influencing the ba distribution in the ocean have distinct 138ba however surveys of 138ba in seawater and particles in the southern ocean so has never been made it is particularly important to understand the impact of the so on the ba cycle as any preformed ba or other sources of ba in the so would have a large impact on its use as a remineralization tracer in the global ocean basis is thus a unique opportunity to enhance knowledge on the ba cycling in this key oceanic region by studying 138ba in seawater and marine particles from the geotraces cruise swings in the so the fellow will spend the first two years at the laboratoire de lenvionnement marin lemar under the supervision of dr planquette this fellowship will allow her to come back to europe with the technical expertise she acquired outside of the eu in the past years she will implement a new technic and will acquire a unique overview of the ba cycle in the global ocean research results will be of interest to worldwide researchers working on the study of the impact of the global carbon cycle promoting european excellence and competitiveness in dedicated european and international carbon export projects
econometrics for macroeconomic policy evaluation

traditionally the evaluation of macroeconomic policy has relied on analyzing specific economic models which often do not correspond to the complex and datarich environments in which real world policy decisions are made to this extent i propose to develop a new framework for evaluating macroeconomic policy decisions policymetrics that is inspired by the robust inference literature in econometrics and makes minimal assumptions on the underlying economic model the methodology detects optimization failures ie instances in which policy decisions do not minimize the welfare loss function and determines the causes and dynamics of such failures all while fully respecting the limitations imposed by the lucas critique part 1 the detection of optimization failures is based on the gradient of the loss function evaluated at the proposed policy choice the key insight is that for large classes of macroeconomic loss functions the gradient only depends on known or estimable sufficient statistics such as forecasts dynamic causal effects and preferences i will tailor the methodology to allow for constrained policy problems risk aversion and the realtime detection of optimization failures part 2 the methodology for understanding optimization failures is inspired by the forecast evaluation literature and aims to infer which tradeoffs across mandates and horizons dynamics and variables were overlooked when setting policy among others i will develop methods that test for systematic optimization failures optimization encompassing and breaks in policy performancei will apply the framework to evaluate contemporaneous and historical monetary fiscal and climate policy decisions from different governments and institutions around the world hereby providing a unique nonmodel based assessment of modern macroeconomic policy
optimisation of digital catch monitoring and reporting in european fisheries

optifish will strive to provide technological solutions that will simultaneously improve the sustainability of fishers operations enhance control processes and strengthen societys trust in their productsoptifish will develop test and recommend a set of innovative technologies and tools supported by artificial intelligence ai to provide the management the fishing sector and the scientist with data on catch volumes catch compositions and the fishing environment the goal is to unlock the full potential of technologies such as electronic and genetic monitoring for automated species recognition based on ai and computer vision to reduce discards unreported landings and unreported fishing activities ultimately establishing a fisheries control and enforcement system fit for the digital age the technologies are not enough alone it is also critical to consider the combination of technologies and the integration of computer vision models the wide range of data sources and their subsequent formats while also addressing stakeholders needs and acceptance this goal cannot be achieved by a single project which is why the aim of optifish is to lay a solid foundation for full technological development from which other projects and initiatives can be built the project will place a strong focus on species recognition in different fisheries equipped with distinctly different catch handling facilities and in different european sea basins to ensure that these innovations are relevant to fisheries management optifish has participation from the norwegian directorate of fisheries and has received written support from the european fisheries control agency efca the basque danish and belgian fisheries authorities