Interleukin-1 family
Nomenclature

Name
Family name
Receptor
Coreceptor
Property
Chromosomal location
IL-1α
IL-1F1
IL-1RI
IL-1RAcP
Proinflammatory
2q14
IL-1β
IL-1F2
IL-1RI
IL-1RAcP
Proinflammatory
2q14
IL-1Ra
IL-1F3
IL-1RI
NA
Antagonist for IL-1α, IL-1β
2q14.2
IL-18
IL-1F4
IL-18Rα
IL-18Rβ
Proinflammatory
11q22.2-q22.3
IL-36Ra
IL-1F5
IL-1Rrp2
NA
Antagonist for IL-36α, IL-36β, IL-36γ
2q14
IL-36α
IL-1F6
IL-1Rrp2
IL-1RAcP
Proinflammatory
2q12 - q14.1
IL-37
IL-1F7
Unknown
Unknown
Anti-inflammatory
2q12 – q14.1
IL-36β
IL-1F8
IL-1Rrp2
IL-1RAcP
Proinflammatory
2q14
IL-36γ
IL1-F9
IL-1Rrp2
IL-1RAcP
Proinflammatory
2q12 – q21
IL-38
IL-1F10
IL-1Rrp2
Unknown
Anti-inflammatory
2q13
IL-33
IL-1F11
ST2
IL-1RAcP
Th2 responses, proinflammatory
9p24.1

Question: For what do IL-1RI and IL-1RAcP serve as receptors and coreceptors?
Answer: IL-1RI and IL-1RAcP serve as receptors and coreceptors for IL-1α and IL-1β.