Conjugated estrogens
Medical uses

Route/form
Estrogen
Low
Standard
High
Oral
Estradiol
0.5–1 mg/day
1–2 mg/day
2–4 mg/day
Oral
Estradiol valerate
0.5–1 mg/day
1–2 mg/day
2–4 mg/day
Oral
Estradiol acetate
0.45–0.9 mg/day
0.9–1.8 mg/day
1.8–3.6 mg/day
Oral
Conjugated estrogens
0.3–0.45 mg/day
0.625 mg/day
0.9–1.25 mg/day
Oral
Esterified estrogens
0.3–0.45 mg/day
0.625 mg/day
0.9–1.25 mg/day
Oral
Estropipate
0.75 mg/day
1.5 mg/day
3 mg/day
Oral
Estriol
1–2 mg/day
2–4 mg/day
4–8 mg/day
Oral
Ethinylestradiola
–
5–10 μg/day
–
Nasal spray
Estradiol
150 μg/day
300 μg/day
–
Transdermal patch
Estradiol
25 μg/dayb
50 μg/dayb
100 μg/dayb
Transdermal gel
Estradiol
0.5 mg/day
1–1.5 mg/day
2–3 mg/day
Vaginal
Estradiol
25 μg/day
–
–
Vaginal
Estriol
30 μg/day
0.5 mg 2x/week
0.5 mg/day
IM or SC injection
Estradiol valerate
–
–
4 mg 1x/4 weeks
IM or SC injection
Estradiol cypionate
1 mg 1x/3–4 weeks
3 mg 1x/3–4 weeks
5 mg 1x/3–4 weeks
IM or SC injection
Estradiol benzoate
0.5 mg 1x/week
1 mg 1x/week
1.5 mg 1x/week
SC implant
Estradiol
25 mg 1x/6 months
50 mg 1x/6 months
100 mg 1x/6 months
Footnotes: a = No longer used or recommended, due to health concerns. b = As a single patch applied once or twice per week (worn for 3–4 days or 7 days), depending on the formulation.
Footnotes: a = No longer used or recommended, due to health concerns. b = As a single patch applied once or twice per week (worn for 3–4 days or 7 days), depending on the formulation.
Footnotes: a = No longer used or recommended, due to health concerns. b = As a single patch applied once or twice per week (worn for 3–4 days or 7 days), depending on the formulation.
Footnotes: a = No longer used or recommended, due to health concerns. b = As a single patch applied once or twice per week (worn for 3–4 days or 7 days), depending on the formulation.
Footnotes: a = No longer used or recommended, due to health concerns. b = As a single patch applied once or twice per week (worn for 3–4 days or 7 days), depending on the formulation.

Question: What are the recommended standard and high dosage for oral CEE?
Answer: Oral CEEs has a daily dosage of 0.625 mg and a daily dosage of 1.25 mg.