Estradiol acetate
Available forms

Route
Ingredient
Form
Dose
Major brand names
Oral
Estradiol
Tablets
0.1, 0.2, 0.5, 1, 2, or 4 mg per tablet
Estrace, Ovocyclin
Oral
Estradiol acetateb
Tablets
0.45, 0.9, or 1.8 mg per tablet
Femtrace
Oral
Estradiol valerate
Tablets
0.5, 1, 2, or 4 mg per tablet
Progynova
Intranasal
Estradiolb
Nasal sprays
150 µg per spray (60 sprays per bottle)
Aerodiol
Transdermal
Estradiol
Patches
14, 25, 37.5, 50, 60, 75, or 100 µg E2 per 24 hours for 3–4 or 7 days
Climara, Estraderm, Vivelle
Transdermal
Estradiol
Gel dispensers
0.06% (0.87 or 1.25 g gel or 0.52 or 0.75 mg E2 per activation)
Elestrin, EstroGel
Transdermal
Estradiol
Gel packets
0.1% (0.25, 0.5, or 1.0 g gel or 2.5, 5, or 10 mg E2 per packet)
DiviGel, Sandrena
Transdermal
Estradiol
Emulsions
0.14% (1.74 g emulsion or 4.35 mg E2 per pouch; delivers 50 µg E2 per day)
Estrasorb
Transdermal
Estradiol
Sprays
1.53 mg per spray
Evamist
Vaginal
Estradiol
Tablets
10 or 25 µg per tablet
Vagifem
Vaginal
Estradiol
Creams
0.01% (0.1 mg E2 per 1.0 g cream)
Estrace
Vaginal
Estradiol
Suppositoriesb
4 or 40 μg per suppository
Ovocyclin
Vaginal
Estradiol
Inserts
4 or 10 µg per insert (replaced daily for 2 weeks and then twice weekly)
Imvexxy
Vaginal
Estradiol
Rings
2 mg per ring (provides 7.5 µg E2 per 24 hours for 3 months)
Estring
Vaginal
Estradiol acetate
Rings
12.4 or 24.8 mg per ring (provide 50 or 100 µg E2 per 24 hours for 3 months)
Femring
Intramuscular injection
Estradiola
Ampoules
1.0 mg/mL
Juvenum E
Intramuscular injection
Estradiol benzoate
Vials/ampoules
0.167, 0.2, 0.333, 1, 1.67, 2, 5, 10, 20, or 25 mg/mL
Progynon-B
Intramuscular injection
Estradiol cypionate
Vials/ampoules
1, 3, or 5 mg/mL
Depo-Estradiol
Intramuscular injection
Estradiol dipropionateb
Vials/ampoules
0.1, 0.2, 0.5, 1, 2.5, or 5 mg/mL
Di-Ovocylin, Progynon-DP
Intramuscular injection
Estradiol enantate
Vials/ampoules
5 or 10 mg/mL (available only in combination with a progestin)
Perlutal, Topasel
Intramuscular injection
Estradiol undecylateb
Vials/ampoules
100 mg/mL
Delestrec, Progynon Depot 100
Intramuscular injection
Estradiol valerate
Vials/ampoules
5, 10, 20, or 40 mg/mL
Delestrogen, Progynon Depot
Intramuscular injection
Polyestradiol phosphate
Vials/ampoules
40 or 80 mg per vial/ampoule
Estradurin
Subcutaneous
Estradiolc
Implants
20, 25, 50, or 100 mg per implant (usually replaced every 6 months)
Estradiol Implants, Meno-Implant
Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.
Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.
Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.
Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.
Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.

Question: What are the possible doses of estradiol acetate for vaginal rings, and what are the sizes of the rings?
Answer: Estradiol acetate comes in the form of 12.4 or 24.8 mg vaginal rings that release 50 or 100 μg/day estradiol for 3 months (Femring).