Dipak-001/mistril_dataset huggingface dataset:
user: How to prevent Breast Cancer ?

assistant: The use of certain medicines and other factors decrease the risk of breast cancer. Anything that decreases your chance of getting a disease is called a protective factor.    Protective factors for breast cancer include the following:            - Taking any of the following:                  -  Estrogen-only hormone therapy after a hysterectomy.       -  Selective estrogen receptor modulators (SERMs).        -  Aromatase inhibitors.                - Less exposure of breast tissue to estrogen made by the body. This can be a result of:                  - Early pregnancy.       - Breastfeeding.                - Getting enough exercise.     - Having any of the following procedures:                  -  Mastectomy to reduce the risk of cancer.       -  Oophorectomy to reduce the risk of cancer.       -  Ovarian ablation.
user: Is Breast Cancer inherited ?

assistant: Breast cancer is sometimes caused by inherited gene mutations (changes). The genes in cells carry the hereditary information that is received from a persons parents. Hereditary breast cancer makes up about 5% to 10% of all breast cancer. Some mutated genes related to breast cancer are more common in certain ethnic groups.   Women who have certain gene mutations, such as a BRCA1 or BRCA2 mutation, have an increased risk of breast cancer. These women also have an increased risk of ovarian cancer, and may have an increased risk of other cancers. Men who have a mutated gene related to breast cancer also have an increased risk of breast cancer. For more information, see the PDQ summary on Male Breast Cancer Treatment.   There are tests that can detect (find) mutated genes. These genetic tests are sometimes done for members of families with a high risk of cancer. See the PDQ summary on Genetics of Breast and Gynecologic Cancers for more information.
user: What are the symptoms of Breast Cancer ?

assistant: Signs of breast cancer include a lump or change in the breast. These and other signs may be caused by breast cancer or by other conditions. Check with your doctor if you have any of the following:         - A lump or thickening in or near the breast or in the underarm area.    - A change in the size or shape of the breast.    - A dimple or puckering in the skin of the breast.    - A nipple turned inward into the breast.    - Fluid, other than breast milk, from the nipple, especially if it's bloody.    - Scaly, red, or swollen skin on the breast, nipple, or areola (the dark area of skin around the nipple).    - Dimples in the breast that look like the skin of an orange, called peau dorange.
user: What is the outlook for Breast Cancer ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer (the size of the tumor and whether it is in the breast only or has spread to lymph nodes or other places in the body).    - The type of breast cancer.    - Estrogen receptor and progesterone receptor levels in the tumor tissue.    - Human epidermal growth factor type 2 receptor (HER2/neu) levels in the tumor tissue.    - Whether the tumor tissue is triple negative (cells that do not have estrogen receptors, progesterone receptors, or high levels of HER2/neu).    - How fast the tumor is growing.    - How likely the tumor is to recur (come back).    - A womans age, general health, and menopausal status (whether a woman is still having menstrual periods).    - Whether the cancer has just been diagnosed or has recurred (come back).
user: What is (are) Prostate Cancer ?

assistant: Key Points
                    - Prostate cancer is a disease in which malignant (cancer) cells form in the tissues of the prostate.    - Signs of prostate cancer include a weak flow of urine or frequent urination.     - Tests that examine the prostate and blood are used to detect (find) and diagnose prostate cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Prostate cancer is a disease in which malignant (cancer) cells form in the tissues of the prostate.
                    The prostate is a gland in the male reproductive system. It lies just below the bladder (the organ that collects and empties urine) and in front of the rectum (the lower part of the intestine). It is about the size of a walnut and surrounds part of the urethra (the tube that empties urine from the bladder). The prostate gland makes fluid that is part of the semen.      Prostate cancer is most common in older men. In the U.S., about 1 out of 5 men will be diagnosed with prostate cancer.
user: What are the symptoms of Prostate Cancer ?

assistant: Signs of prostate cancer include a weak flow of urine or frequent urination. These and other signs and symptoms may be caused by prostate cancer or by other conditions. Check with your doctor if you have any of the following:         - Weak or interrupted ("stop-and-go") flow of urine.    - Sudden urge to urinate.    - Frequent urination (especially at night).    - Trouble starting the flow of urine.    - Trouble emptying the bladder completely.    - Pain or burning while urinating.    -  Blood in the urine or semen.    - A pain in the back, hips, or pelvis that doesn't go away.    - Shortness of breath, feeling very tired, fast heartbeat, dizziness, or pale skin caused by anemia.        Other conditions may cause the same symptoms. As men age, the prostate may get bigger and block the urethra or bladder. This may cause trouble urinating or sexual problems. The condition is called benign prostatic hyperplasia (BPH), and although it is not cancer, surgery may be needed. The symptoms of benign prostatic hyperplasia or of other problems in the prostate may be like symptoms of prostate cancer.
user: How to diagnose Prostate Cancer ?

assistant: Tests that examine the prostate and blood are used to detect (find) and diagnose prostate cancer. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Digital rectal exam (DRE): An exam of the rectum. The doctor or nurse inserts a lubricated, gloved finger into the rectum and feels the prostate through the rectal wall for lumps or abnormal areas.     -   Prostate-specific antigen (PSA) test : A test that measures the level of PSA in the blood. PSA is a substance made by the prostate that may be found in an increased amount in the blood of men who have prostate cancer. PSA levels may also be high in men who have an infection or inflammation of the prostate or BPH (an enlarged, but noncancerous, prostate).    -   Transrectal ultrasound : A procedure in which a probe that is about the size of a finger is inserted into the rectum to check the prostate. The probe is used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram. Transrectal ultrasound may be used during a biopsy procedure.    -  Transrectal magnetic resonance imaging (MRI): A procedure that uses a strong magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. A probe that gives off radio waves is inserted into the rectum near the prostate. This helps the MRI machine make clearer pictures of the prostate and nearby tissue. A transrectal MRI is done to find out if the cancer has spread outside the prostate into nearby tissues. This procedure is also called nuclear magnetic resonance imaging (NMRI).    -  Biopsy: The removal of cells or tissues so they can be viewed under a microscope by a pathologist. The pathologist will check the tissue sample to see if there are cancer cells and find out the Gleason score. The Gleason score ranges from 2-10 and describes how likely it is that a tumor will spread. The lower the number, the less likely the tumor is to spread.  A transrectal biopsy is used to diagnose prostate cancer. A transrectal biopsy is the removal of tissue from the prostate by inserting a thin needle through the rectum and into the prostate. This procedure is usually done using transrectal ultrasound to help guide where samples of tissue are taken from. A pathologist views the tissue under a microscope to look for cancer cells.
user: What is the outlook for Prostate Cancer ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer (level of PSA, Gleason score, grade of the tumor, how much of the prostate is affected by the cancer, and whether the cancer has spread to other places in the body).    - The patients age.    - Whether the cancer has just been diagnosed or has recurred (come back).        Treatment options also may depend on the following:         - Whether the patient has other health problems.    - The expected side effects of treatment.    - Past treatment for prostate cancer.    - The wishes of the patient.        Most men diagnosed with prostate cancer do not die of it.
user: what research (or clinical trials) is being done for Prostate Cancer ?

assistant: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Cryosurgery     Cryosurgery is a treatment that uses an instrument to freeze and destroy prostate cancer cells. Ultrasound is used to find the area that will be treated. This type of treatment is also called cryotherapy.    Cryosurgery can cause impotence and leakage of urine from the bladder or stool from the rectum.       High-intensityfocused ultrasound therapy     High-intensityfocused ultrasound therapy is a treatment that uses ultrasound (high-energy sound waves) to destroy cancer cells. To treat prostate cancer, an endorectal probe is used to make the sound waves.       Proton beam radiation therapy     Proton beam radiation therapy is a type of high-energy, external radiation therapy that targets tumors with streams of protons (small, positively charged particles). This type of radiation therapy is being studied in the treatment of prostate cancer.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What is (are) Osteosarcoma and Malignant Fibrous Histiocytoma of Bone ?

assistant: Key Points
                    - Osteosarcoma and malignant fibrous histiocytoma (MFH) of the bone are diseases in which malignant (cancer) cells form in bone.    - Having past treatment with radiation can increase the risk of osteosarcoma.    - Signs and symptoms of osteosarcoma and MFH include swelling over a bone or a bony part of the body and joint pain.     - Imaging tests are used to detect (find) osteosarcoma and MFH.    - A biopsy is done to diagnose osteosarcoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Osteosarcoma and malignant fibrous histiocytoma (MFH) of the bone are diseases in which malignant (cancer) cells form in bone.
                    Osteosarcoma usually starts in osteoblasts, which are a type of bone cell that becomes new bone tissue. Osteosarcoma is most common in adolescents. It commonly forms in the ends of the long bones of the body, which include bones of the arms and legs. In children and adolescents, it often forms in the bones near the knee. Rarely, osteosarcoma may be found in soft tissue or organs in the chest or abdomen.   Osteosarcoma is the most common type of bone cancer. Malignant fibrous histiocytoma (MFH) of bone is a rare tumor of the bone. It is treated like osteosarcoma.     Ewing sarcoma is another kind of bone cancer, but it is not covered in this summary. See the PDQ summary about Ewing Sarcoma Treatment for more information.
user: Who is at risk for Osteosarcoma and Malignant Fibrous Histiocytoma of Bone? ?

assistant: Having past treatment with radiation can increase the risk of osteosarcoma. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your child's doctor if you think your child may be at risk. Risk factors for osteosarcoma include the following:         - Past treatment with radiation therapy.    - Past treatment with anticancer drugs called alkylating agents.    - Having a certain change in the retinoblastoma gene.    - Having certain conditions, such as the following:               -  Bloom syndrome.      -  Diamond-Blackfan anemia.      -  Li-Fraumeni syndrome.      -  Paget disease.      -  Hereditary retinoblastoma.      -  Rothmund-Thomson syndrome.      -  Werner syndrome.
user: What are the symptoms of Osteosarcoma and Malignant Fibrous Histiocytoma of Bone ?

assistant: Signs and symptoms of osteosarcoma and MFH include swelling over a bone or a bony part of the body and joint pain. These and other signs and symptoms may be caused by osteosarcoma or MFH or by other conditions. Check with a doctor if your child has any of the following:         - Swelling over a bone or bony part of the body.    - Pain in a bone or joint.    - A bone that breaks for no known reason.
user: How to diagnose Osteosarcoma and Malignant Fibrous Histiocytoma of Bone ?

assistant: Imaging tests are used to detect (find) osteosarcoma and MFH.
	                        Imaging tests are done before the biopsy. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   X-ray : An x-ray of the organs and bones inside the body. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.     -   CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.    -   MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear magnetic resonance imaging (NMRI).
	                    
	                    
	                    	A biopsy is done to diagnose osteosarcoma.
	                   		Cells and tissues are removed during a biopsy so they can be viewed under a microscope by a pathologist to check for signs of cancer. It is important that the biopsy be done by a surgeon who is an expert in treating cancer of the bone. It is best if that surgeon is also the one who removes the tumor. The biopsy and the surgery to remove the tumor are planned together. The way the biopsy is done affects which type of surgery can be done later.    The type of biopsy that is done will be based on the size of the tumor and where it is in the body. There are two types of biopsy that may be used:         -   Core biopsy : The removal of tissue using a wide needle.    -   Incisional biopsy : The removal of part of a lump or a sample of tissue that doesn't look normal.         The following test may be done on the tissue that is removed:          -   Light and electron microscopy : A laboratory test in which cells in a sample of tissue are viewed under regular and high-powered microscopes to look for certain changes in the cells.
user: What is the outlook for Osteosarcoma and Malignant Fibrous Histiocytoma of Bone ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) is affected by certain factors before and after treatment.    The prognosis of untreated osteosarcoma and MFH depends on the following:         - Where the tumor is in the body and whether tumors formed in more than one bone.    - The size of the tumor.    - Whether the cancer has spread to other parts of the body and where it has spread.    - The type of tumor (based on how the cancer cells look under a microscope).    - The patient's age and weight at diagnosis.    - Whether the tumor has caused a break in the bone.     - Whether the patient has certain genetic diseases.        After osteosarcoma or MFH is treated, prognosis also depends on the following:         - How much of the cancer was killed by chemotherapy.    - How much of the tumor was taken out by surgery.    - Whether chemotherapy is delayed for more than 3 weeks after surgery takes place.    - Whether the cancer has recurred (come back) within 2 years of diagnosis.        Treatment options for osteosarcoma and MFH depend on the following:         - Where the tumor is in the body.    - The size of the tumor.    - The stage of the cancer.    - Whether the bones are still growing.    - The patient's age and general health.    - The desire of the patient and family for the patient to be able to participate in activities such as sports or have a certain appearance.    - Whether the cancer is newly diagnosed or has recurred after treatment.
user: What is (are) Oral Cavity and Oropharyngeal Cancer ?

assistant: Key Points
                    - Oral cavity and oropharyngeal cancer are diseases in which malignant (cancer) cells form in the mouth and throat.    - The number of new cases of oral cavity and oropharyngeal cancer and the number of deaths from oral cavity and oropharyngeal cancer varies by race and gender.    - Different factors increase or decrease the risk of oral cavity and oropharyngeal cancer.
                
                
                    Oral cavity and oropharyngeal cancer are diseases in which malignant (cancer) cells form in the mouth and throat.
                    Oral cavity cancer forms in any of these tissues of the oral cavity:         - The front two thirds of the tongue.    - The gingiva (gums).    - The buccal mucosa (the lining of the inside of the cheeks).    - The floor (bottom) of the mouth under the tongue.    - The hard palate (the front of the roof of the mouth).    - The retromolar trigone (the small area behind the wisdom teeth).          Oropharyngeal cancer forms in any of these tissues of the oropharynx:         - The middle part of the pharynx (throat) behind the mouth.    - The back one third of the tongue.    - The soft palate (the back of the roof of the mouth).    - The side and back walls of the throat.    - The tonsils.          Most oral cavity and oropharyngeal cancers start in squamous cells, the thin, flat cells that line the lips, oral cavity, and oropharynx. Cancer that forms in squamous cells is called squamous cell carcinoma.   See the following PDQ summaries for more information about the screening, diagnosis, and treatment of oral cavity and oropharyngeal cancer:         -  Oral Cavity and Oropharyngeal Cancer Prevention     -  Lip and Oral Cavity Cancer Treatment     -  Oropharyngeal Cancer Treatment
                
                
                    The number of new cases of oral cavity and oropharyngeal cancer and the number of deaths from oral cavity and oropharyngeal cancer varies by race and gender.
                    Over the past ten years, the number of new cases and deaths from oral cavity and oropharyngeal cancer slightly increased in white men and women. The number slightly decreased among black men and women.   Oral cavity and oropharyngeal cancer is more common in men than in women. Although oral cavity and oropharyngeal cancer may occur in adults of any age, it occurs most often in those aged 55 to 64 years.   France, Brazil, and parts of Asia have much higher rates of oral cavity and oropharyngeal cancer than most other countries.    The number of new cases of oropharyngeal cancer caused by certain types of human papillomavirus (HPV) infection has increased. One kind of HPV, called HPV 16, is often passed from one person to another during sexual activity.
user: Who is at risk for Oral Cavity and Oropharyngeal Cancer? ?

assistant: The number of new cases of oral cavity and oropharyngeal cancer and the number of deaths from oral cavity and oropharyngeal cancer varies by race and gender. Over the past ten years, the number of new cases and deaths from oral cavity and oropharyngeal cancer slightly increased in white men and women. The number slightly decreased among black men and women.   Oral cavity and oropharyngeal cancer is more common in men than in women. Although oral cavity and oropharyngeal cancer may occur in adults of any age, it occurs most often in those aged 55 to 64 years.   France, Brazil, and parts of Asia have much higher rates of oral cavity and oropharyngeal cancer than most other countries.    The number of new cases of oropharyngeal cancer caused by certain types of human papillomavirus (HPV) infection has increased. One kind of HPV, called HPV 16, is often passed from one person to another during sexual activity.
user: Who is at risk for Oral Cavity and Oropharyngeal Cancer? ?

assistant: Different factors increase or decrease the risk of oral cavity and oropharyngeal cancer. Anything that increases your chance of getting a disease is called a risk factor. Anything that decreases your chance of getting a disease is called a protective factor.    For information about risk factors and protective factors for oral cavity and oropharyngeal cancer, see the PDQ summary on Oral Cavity and Oropharyngeal Cancer Prevention.