Dipak-001/mistril_dataset huggingface dataset:
user: How to diagnose Chronic Myelogenous Leukemia ?

assistant: Tests that examine the blood and bone marrow are used to detect (find) and diagnose chronic myelogenous leukemia.. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease such as an enlarged spleen. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Complete blood count (CBC) with differential : A procedure in which a sample of blood is drawn and checked for the following:                -  The number of red blood cells and platelets.      - The number and type of white blood cells.      - The amount of hemoglobin (the protein that carries oxygen) in the red blood cells.      - The portion of the blood sample made up of red blood cells.              -   Blood chemistry studies : A procedure in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease.     -   Bone marrow aspiration and biopsy : The removal of bone marrow, blood, and a small piece of bone by inserting a needle into the hipbone or breastbone. A pathologist views the bone marrow, blood, and bone under a microscope to look for abnormal cells. One of the following tests may be done on the samples of blood or bone marrow tissue that are removed:                -  Cytogenetic analysis: A test in which cells in a sample of blood or bone marrow are viewed under a microscope to look for certain changes in the chromosomes, such as the Philadelphia chromosome.      -  FISH (fluorescence in situ hybridization): A laboratory technique used to look at genes or chromosomes in cells and tissues. Pieces of DNA that contain a fluorescent dye are made in the laboratory and added to cells or tissues on a glass slide. When these pieces of DNA bind to specific genes or areas of chromosomes on the slide, they light up when viewed under a microscope with a special light.       -  Reverse transcriptionpolymerase chain reaction (RTPCR): A laboratory test in which cells in a sample of tissue are studied using chemicals to look for certain changes in the structure or function of genes.
user: What is the outlook for Chronic Myelogenous Leukemia ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The patients age.    - The phase of CML.    - The amount of blasts in the blood or bone marrow.    - The size of the spleen at diagnosis.    - The patients general health.
user: What are the stages of Chronic Myelogenous Leukemia ?

assistant: Key Points
                    - After chronic myelogenous leukemia has been diagnosed, tests are done to find out if the cancer has spread.    - Chronic myelogenous leukemia has 3 phases.         - Chronic phase     - Accelerated phase     - Blastic phase
                
                
                    After chronic myelogenous leukemia has been diagnosed, tests are done to find out if the cancer has spread.
                    Staging is the process used to find out how far the cancer has spread. There is no standard staging system for chronic myelogenous leukemia (CML). Instead, the disease is classified by phase: chronic phase, accelerated phase, or blastic phase. It is important to know the phase in order to plan treatment. The information from tests and procedures done to detect (find) and diagnose chronic myelogenous leukemia is also used to plan treatment.
                
                
                    Chronic myelogenous leukemia has 3 phases.
                    As the amount of blast cells increases in the blood and bone marrow, there is less room for healthy white blood cells, red blood cells, and platelets. This may result in infections, anemia, and easy bleeding, as well as bone pain and pain or a feeling of fullness below the ribs on the left side. The number of blast cells in the blood and bone marrow and the severity of signs or symptoms determine the phase of the disease.     Chronic phase    In chronic phase CML, fewer than 10% of the cells in the blood and bone marrow are blast cells.       Accelerated phase    In accelerated phase CML, 10% to 19% of the cells in the blood and bone marrow are blast cells.       Blastic phase    In blastic phase CML, 20% or more of the cells in the blood or bone marrow are blast cells. When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.
user: what research (or clinical trials) is being done for Chronic Myelogenous Leukemia ?

assistant: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What is (are) Merkel Cell Carcinoma ?

assistant: Key Points
                    - Merkel cell carcinoma is a very rare disease in which malignant (cancer) cells form in the skin.    - Sun exposure and having a weak immune system can affect the risk of Merkel cell carcinoma.    - Merkel cell carcinoma usually appears as a single painless lump on sun-exposed skin.    - Tests and procedures that examine the skin are used to detect (find) and diagnose Merkel cell carcinoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Merkel cell carcinoma is a very rare disease in which malignant (cancer) cells form in the skin.
                    Merkel cells are found in the top layer of the skin. These cells are very close to the nerve endings that receive the sensation of touch. Merkel cell carcinoma, also called neuroendocrine carcinoma of the skin or trabecular cancer, is a very rare type of skin cancer that forms when Merkel cells grow out of control. Merkel cell carcinoma starts most often in areas of skin exposed to the sun, especially the head and neck, as well as the arms, legs, and trunk.     Merkel cell carcinoma tends to grow quickly and to metastasize (spread) at an early stage. It usually spreads first to nearby lymph nodes and then may spread to lymph nodes or skin in distant parts of the body, lungs, brain, bones, or other organs.
user: Who is at risk for Merkel Cell Carcinoma? ?

assistant: un exposure and having a weak immune system can affect the risk of Merkel cell carcinoma. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for Merkel cell carcinoma include the following:         - Being exposed to a lot of natural sunlight.    - Being exposed to artificial sunlight, such as from tanning beds or psoralen and ultraviolet A (PUVA) therapy for psoriasis.    -  Having an immune system weakened by disease, such as chronic lymphocytic leukemia or HIV infection.     - Taking drugs that make the immune system less active, such as after an organ transplant.    -  Having a history of other types of cancer.    - Being older than 50 years, male, or white.
user: What are the symptoms of Merkel Cell Carcinoma ?

assistant: Merkel cell carcinoma usually appears as a single painless lump on sun-exposed skin. This and other changes in the skin may be caused by Merkel cell carcinoma or by other conditions. Check with your doctor if you see changes in your skin.   Merkel cell carcinoma usually appears on sun-exposed skin as a single lump that is:          - Fast-growing.     - Painless.    - Firm and dome-shaped or raised.    - Red or violet in color.
user: How to diagnose Merkel Cell Carcinoma ?

assistant: Tests and procedures that examine the skin are used to detect (find) and diagnose Merkel cell carcinoma. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -  Full-body skin exam: A doctor or nurse checks the skin for bumps or spots that look abnormal in color, size, shape, or texture. The size, shape, and texture of the lymph nodes will also be checked.    -  Skin biopsy : The removal of skin cells or tissues so they can be viewed under a microscope by a pathologist to check for signs of cancer.
user: What is the outlook for Merkel Cell Carcinoma ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:          - The stage of the cancer (the size of the tumor and whether it has spread to the lymph nodes or other parts of the body).    - Where the cancer is in the body.    - Whether the cancer has just been diagnosed or has recurred (come back).    - The patient's age and general health.        Prognosis also depends on how deeply the tumor has grown into the skin.
user: what research (or clinical trials) is being done for Merkel Cell Carcinoma ?

assistant: New types of treatment are being tested in clinical trials.
                    
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What is (are) Breast Cancer ?

assistant: Key Points
                    - Breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast.    - Breast cancer is the second leading cause of death from cancer in American women.    -  Different factors increase or decrease the risk of breast cancer.
                
                
                    Breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast.
                    The breast is made up of lobes and ducts. Each breast has 15 to 20 sections called lobes, which have many smaller sections called lobules. Lobules end in dozens of tiny bulbs that can produce milk. The lobes, lobules, and bulbs are linked by thin tubes called ducts.     Each breast also contains blood vessels and lymph vessels. The lymph vessels carry an almost colorless fluid called lymph. Lymph vessels lead to organs called lymph nodes. Lymph nodes are small bean-shaped structures that are found throughout the body. They filter substances in lymph and help fight infection and disease. Clusters of lymph nodes are found near the breast in the axilla (under the arm), above the collarbone, and in the chest.   See the following PDQ summaries for more information about breast cancer:         -  Breast Cancer Prevention     -  Breast Cancer Treatment     -  Genetics of Breast and Gynecologic Cancers
                
                
                    Breast cancer is the second leading cause of death from cancer in American women.
                    Women in the United States get breast cancer more than any other type of cancer except for skin cancer. Breast cancer is second only to lung cancer as a cause of cancer death in women.    Breast cancer occurs more often in white women than in black women. However, black women are more likely than white women to die from the disease.   Breast cancer occurs in men also, but the number of cases is small.
user: Who is at risk for Breast Cancer? ?

assistant: Different factors increase or decrease the risk of breast cancer. Anything that increases your chance of getting a disease is called a risk factor. Anything that decreases your chance of getting a disease is called a protective factor.    For information about risk factors and protective factors for breast cancer, see the PDQ summary on Breast Cancer Prevention.
user: what research (or clinical trials) is being done for Breast Cancer ?

assistant: Other screening tests are being studied in clinical trials.
                    Thermography     Thermography is a procedure in which a special camera that senses heat is used to record the temperature of the skin that covers the breasts. A computer makes a map of the breast showing the changes in temperature. Tumors can cause temperature changes that may show up on the thermogram.     There have been no clinical trials of thermography to find out how well it detects breast cancer or if having the procedure decreases the risk of dying from breast cancer.       Tissue sampling    Breast tissue sampling is taking cells from breast tissue to check under a microscope. Abnormal cells in breast fluid have been linked to an increased risk of breast cancer in some studies. Scientists are studying whether breast tissue sampling can be used to find breast cancer at an early stage or predict the risk of developing breast cancer. Three ways of taking tissue samples are being studied:            -  Fine-needle aspiration: A thin needle is inserted into the breast tissue around the areola (darkened area around the nipple) to take out a sample of cells and fluid.     - Nipple aspiration: The use of gentle suction to collect fluid through the nipple. This is done with a device similar to the breast pumps used by women who are breast-feeding.     -  Ductal lavage: A hair-size catheter (tube) is inserted into the nipple and a small amount of salt water is released into the duct. The water picks up breast cells and is removed.               Screening clinical trials are taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI website.
user: What is (are) Breast Cancer ?

assistant: Key Points
                    - Breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast.    - Breast cancer is the second most common type of cancer in American women.
                
                
                    Breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast.
                    The breast is made up of lobes and ducts. Each breast has 15 to 20 sections called lobes, which have many smaller sections called lobules. Lobules end in dozens of tiny bulbs that can make milk. The lobes, lobules, and bulbs are linked by thin tubes called ducts.     Each breast also has blood vessels and lymph vessels. The lymph vessels carry an almost colorless fluid called lymph. Lymph vessels lead to organs called lymph nodes. Lymph nodes are small bean-shaped structures that are found throughout the body. They filter lymph and store white blood cells that help fight infection and disease. Clusters of lymph nodes are found near the breast in the axilla (under the arm), above the collarbone, and in the chest.   See the following PDQ summaries for more information about breast cancer:         -  Breast Cancer Screening     -  Breast Cancer Treatment     -  Breast Cancer Treatment and Pregnancy     -  Male Breast Cancer Treatment     -  Genetics of Breast and Ovarian Cancer
                
                
                    Breast cancer is the second most common type of cancer in American women.
                    Women in the United States get breast cancer more than any other type of cancer except skin cancer. Breast cancer is second to lung cancer as a cause of cancer death in American women. However, deaths from breast cancer have decreased a little bit every year between 2003 and 2012. Breast cancer also occurs in men, but the number of new cases is small.
user: what research (or clinical trials) is being done for Breast Cancer ?

assistant: Cancer prevention clinical trials are used to study ways to prevent cancer.
                    Cancer prevention clinical trials are used to study ways to lower the risk of developing certain types of cancer. Some cancer prevention trials are conducted with healthy people who have not had cancer but who have an increased risk for cancer. Other prevention trials are conducted with people who have had cancer and are trying to prevent another cancer of the same type or to lower their chance of developing a new type of cancer. Other trials are done with healthy volunteers who are not known to have any risk factors for cancer.   The purpose of some cancer prevention clinical trials is to find out whether actions people take can prevent cancer. These may include exercising more or quitting smoking or taking certain medicines, vitamins, minerals, or food supplements.
                
                
                    New ways to prevent breast cancer are being studied in clinical trials.
user: What is (are) Extragonadal Germ Cell Tumors ?

assistant: Key Points
                    - Extragonadal germ cell tumors form from developing sperm or egg cells that travel from the gonads to other parts of the body.    - Age and gender can affect the risk of extragonadal germ cell tumors.     - Signs and symptoms of extragonadal germ cell tumors include breathing problems and chest pain.     - Imaging and blood tests are used to detect (find) and diagnose extragonadal germ cell tumors.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Extragonadal germ cell tumors form from developing sperm or egg cells that travel from the gonads to other parts of the body.
                    " Extragonadal" means outside of the gonads (sex organs). When cells that are meant to form sperm in the testicles or eggs in the ovaries travel to other parts of the body, they may grow into extragonadal germ cell tumors. These tumors may begin to grow anywhere in the body but usually begin in organs such as the pineal gland in the brain, in the mediastinum (area between the lungs), or in the retroperitoneum (the back wall of the abdomen).     Extragonadal germ cell tumors can be benign (noncancer) or malignant (cancer). Benign extragonadal germ cell tumors are called benign teratomas. These are more common than malignant extragonadal germ cell tumors and often are very large.   Malignant extragonadal germ cell tumors are divided into two types, nonseminoma and seminoma. Nonseminomas tend to grow and spread more quickly than seminomas. They usually are large and cause signs and symptoms. If untreated, malignant extragonadal germ cell tumors may spread to the lungs, lymph nodes, bones, liver, or other parts of the body.   For information about germ cell tumors in the ovaries and testicles, see the following PDQ summaries:         -  Ovarian Germ Cell Tumors Treatment     -  Testicular Cancer Treatment
user: Who is at risk for Extragonadal Germ Cell Tumors? ?

assistant: Age and gender can affect the risk of extragonadal germ cell tumors. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for malignant extragonadal germ cell tumors include the following:         - Being male.    - Being age 20 or older.    - Having Klinefelter syndrome.
user: What are the symptoms of Extragonadal Germ Cell Tumors ?

assistant: Signs and symptoms of extragonadal germ cell tumors include breathing problems and chest pain. Malignant extragonadal germ cell tumors may cause signs and symptoms as they grow into nearby areas. Other conditions may cause the same signs and symptoms. Check with your doctor if you have any of the following:         - Chest pain.    - Breathing problems.    - Cough.    -  Fever.    - Headache.    - Change in bowel habits.    - Feeling very tired.    - Trouble walking.    - Trouble in seeing or moving the eyes.