Dipak-001/mistril_dataset huggingface dataset:
user: What are the symptoms of Ewing Sarcoma ?

assistant: Signs and symptoms of Ewing sarcoma include swelling and pain near the tumor. These and other signs and symptoms may be caused by Ewing sarcoma or by other conditions. Check with your childs doctor if your child has any of the following:          - Pain and/or swelling, usually in the arms, legs, chest, back, or pelvis.    - A lump (which may feel soft and warm) in the arms, legs, chest, or pelvis.    -  Fever for no known reason.    - A bone that breaks for no known reason.
user: What is the outlook for Ewing Sarcoma ?

assistant: Certain factors affect prognosis (chance of recovery). The factors that affect prognosis (chance of recovery) are different before and after treatment.    Before treatment, prognosis depends on:         - Whether the tumor has spread to lymph nodes or distant parts of the body.     - Where in the body the tumor started.    - Whether the tumor formed in the bone or in soft tissue.    - How large the tumor is at when the tumor is diagnosed.    - Whether the LDH level in the blood is higher than normal.    - Whether the tumor has certain gene changes.     - Whether the child is younger than 15 years.     - The patient's gender.     - Whether the child has had treatment for a different cancer before Ewing sarcoma.    - Whether the tumor has just been diagnosed or has recurred (come back).        After treatment, prognosis is affected by:         - Whether the tumor was completely removed by surgery.    - Whether the tumor responds to chemotherapy or radiation therapy.        If the cancer recurs after initial treatment, prognosis depends on:         - Whether the cancer came back more than two years after the initial treatment.    - Where in the body the tumor came back.    - The type of initial treatment given.
user: What are the stages of Ewing Sarcoma ?

assistant: Key Points
                    - The results of diagnostic and staging tests are used to find out if cancer cells have spread.    - Ewing sarcoma is described based on whether the cancer has spread from the bone or soft tissue in which the cancer began.          - Localized Ewing sarcoma     - Metastatic Ewing sarcoma        - There are three ways that cancer spreads in the body.    - Cancer may spread from where it began to other parts of the body.
                
                
                    The results of diagnostic and staging tests are used to find out if cancer cells have spread.
                    The process used to find out if cancer has spread from where it began to other parts of the body is called staging. There is no standard staging system for Ewing sarcoma. The results of the tests and procedures done to diagnose and stage Ewing sarcoma are used to group the tumors into localized or metastatic.
                
                
                    Ewing sarcoma is described based on whether the cancer has spread from the bone or soft tissue in which the cancer began.
                    Ewing sarcoma is described as either localized or metastatic.      Localized Ewing sarcoma    The cancer is found in the bone or soft tissue in which it began and may have spread to nearby tissue, including nearby lymph nodes.       Metastatic Ewing sarcoma     The cancer has spread from the bone or soft tissue in which it began to other parts of the body. In Ewing tumor of bone, the cancer most often spreads to the lung, other bones, and bone marrow.
                
                
                    There are three ways that cancer spreads in the body.
                    Cancer can spread through tissue, the lymph system, and the blood:         - Tissue. The cancer spreads from where it began by growing into nearby areas.     - Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.     - Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.
                
                
                    Cancer may spread from where it began to other parts of the body.
                    When cancer spreads to another part of the body, it is called metastasis. Cancer cells break away from where they began (the primary tumor) and travel through the lymph system or blood.         - Lymph system. The cancer gets into the lymph system, travels through the lymph vessels, and forms a tumor (metastatic tumor) in another part of the body.    - Blood. The cancer gets into the blood, travels through the blood vessels, and forms a tumor (metastatic tumor) in another part of the body.        The metastatic tumor is the same type of cancer as the primary tumor. For example, if Ewing sarcoma spreads to the lung, the cancer cells in the lung are actually Ewing sarcoma cells. The disease is metastatic Ewing sarcoma, not lung cancer.
user: what research (or clinical trials) is being done for Ewing Sarcoma ?

assistant: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Chimeric antigen receptor (CAR) T-cell therapy     CAR T-cell therapy is a type of immunotherapy that changes the patient's T cells (a type of immune system cell) so they will attack certain proteins on the surface of cancer cells. T cells are taken from the patient and special receptors are added to their surface in the laboratory. The changed cells are called chimeric antigen receptor (CAR) T cells. The CAR T cells are grown in the laboratory and given to the patient by infusion. The CAR T cells multiply in the patient's blood and attack cancer cells. CAR T-cell therapy is being studied in the treatment of Ewing sarcoma that has recurred.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What causes Childhood Brain and Spinal Cord Tumors ?

assistant: The cause of most childhood brain and spinal cord tumors is unknown.
user: What are the symptoms of Childhood Brain and Spinal Cord Tumors ?

assistant: The signs and symptoms of childhood brain and spinal cord tumors are not the same in every child. Signs and symptoms depend on the following:         - Where the tumor forms in the brain or spinal cord.    - The size of the tumor.    - How fast the tumor grows.    - The child's age and development.        Signs and symptoms may be caused by childhood brain and spinal cord tumors or by other conditions, including cancer that has spread to the brain. Check with your child's doctor if your child has any of the following:      Brain Tumor Signs and Symptoms       - Morning headache or headache that goes away after vomiting.    - Frequent nausea and vomiting.     - Vision, hearing, and speech problems.    - Loss of balance and trouble walking.    - Unusual sleepiness or change in activity level.     - Unusual changes in personality or behavior.    -  Seizures.    - Increase in the head size (in infants).           Spinal Cord Tumor Signs and Symptoms       - Back pain or pain that spreads from the back towards the arms or legs.    - A change in bowel habits or trouble urinating.    - Weakness in the legs.    - Trouble walking.        In addition to these signs and symptoms of brain and spinal cord tumors, some children are unable to reach certain growth and development milestones such as sitting up, walking, and talking in sentences.
user: How to diagnose Childhood Brain and Spinal Cord Tumors ?

assistant: Tests that examine the brain and spinal cord are used to detect (find) childhood brain and spinal cord tumors. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.     -   Neurological exam : A series of questions and tests to check the brain, spinal cord, and nerve function. The exam checks a persons mental status, coordination, and ability to walk normally, and how well the muscles, senses, and reflexes work. This may also be called a neuro exam or a neurologic exam.     -   MRI (magnetic resonance imaging) with gadolinium : A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of the brain and spinal cord. A substance called gadolinium is injected into a vein. The gadolinium collects around the cancer cells so they show up brighter in the picture. This procedure is also called nuclear magnetic resonance imaging (NMRI).    -   Serum tumor marker test : A procedure in which a sample of blood is examined to measure the amounts of certain substances released into the blood by organs, tissues, or tumor cells in the body. Certain substances are linked to specific types of cancer when found in increased levels in the blood. These are called tumor markers.
                         Most childhood brain tumors are diagnosed and removed in surgery. If doctors think there might be a brain tumor, a biopsy may be done to remove a sample of tissue. For tumors in the brain, the biopsy is done by removing part of the skull and using a needle to remove a sample of tissue. A pathologist views the tissue under a microscope to look for cancer cells. If cancer cells are found, the doctor may remove as much tumor as safely possible during the same surgery. The pathologist checks the cancer cells to find out the type and grade of brain tumor. The grade of the tumor is based on how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread.    The following test may be done on the sample of tissue that is removed:         -   Immunohistochemistry : A test that uses antibodies to check for certain antigens in a sample of tissue. The antibody is usually linked to a radioactive substance or a dye that causes the tissue to light up under a microscope. This type of test may be used to tell the difference between different types of cancer.         
                    					Some childhood brain and spinal cord tumors are diagnosed by imaging tests. Sometimes a biopsy or surgery cannot be done safely because of where the tumor formed in the brain or spinal cord. These tumors are diagnosed based on the results of imaging tests and other procedures.
user: What is the outlook for Childhood Brain and Spinal Cord Tumors ?

assistant: Certain factors affect prognosis (chance of recovery). The prognosis (chance of recovery) depends on the following:         - Whether there are any cancer cells left after surgery.    - The type of tumor.    - Where the tumor is in the body.    - The child's age.    - Whether the tumor has just been diagnosed or has recurred (come back).
user: what research (or clinical trials) is being done for Childhood Brain and Spinal Cord Tumors ?

assistant: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     High-dose chemotherapy with stem cell transplant     High-dose chemotherapy with stem cell transplant is a way of giving high doses of chemotherapy and replacing blood -forming cells destroyed by the cancer treatment. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After the chemotherapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the bodys blood cells.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.    Clinical trials are taking place in many parts of the country. Information about clinical trials is available from the NCI website.
user: Who is at risk for Testicular Cancer? ?

assistant: Health history can affect the risk of testicular cancer.
	                    Anything that increases the chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for testicular cancer include:          - Having had an undescended testicle.    - Having had abnormal development of the testicles.    - Having a personal history of testicular cancer.    - Having a family history of testicular cancer (especially in a father or brother).    - Being white.
	                
	                
	                    Treatment for testicular cancer can cause infertility.
	                    Certain treatments for testicular cancer can cause infertility that may be permanent. Patients who may wish to have children should consider sperm banking before having treatment. Sperm banking is the process of freezing sperm and storing it for later use.
user: what research (or clinical trials) is being done for Testicular Cancer ?

assistant: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What is (are) Langerhans Cell Histiocytosis ?

assistant: Key Points
                    - Langerhans cell histiocytosis is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body.    - Family history or having a parent who was exposed to certain chemicals may increase the risk of LCH.    - The signs and symptoms of LCH depend on where it is in the body.         - Skin and nails     - Mouth     - Bone     - Lymph nodes and thymus     - Endocrine system      - Central nervous system (CNS)     - Liver and spleen     - Lung     - Bone marrow        - Tests that examine the organs and body systems where LCH may occur are used to detect (find) and diagnose LCH.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Langerhans cell histiocytosis is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body.
                    Langerhans cell histiocytosis (LCH) is a rare cancer that begins in LCH cells (a type of dendritic cell which fights infection). Sometimes there are mutations (changes) in LCH cells as they form. These include mutations of the  BRAF  gene. These changes may make the LCH cells grow and multiply quickly. This causes LCH cells to build up in certain parts of the body, where they can damage tissue or form lesions.    LCH is not a disease of the Langerhans cells that normally occur in the skin.   LCH may occur at any age, but is most common in young children. Treatment of LCH in children is different from treatment of LCH in adults. The treatments for LCH in children and adults are described in separate sections of this summary.   Check the list of NCI-supported cancer clinical trials that are now accepting patients with childhood Langerhans cell histiocytosis. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your child's doctor about clinical trials that may be right for your child. General information about clinical trials is available from the NCI website.
user: Who is at risk for Langerhans Cell Histiocytosis? ?

assistant: Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for LCH include the following:         - Having a parent who was exposed to certain chemicals such as benzene.    - Having a parent who was exposed to metal, granite, or wood dust in the workplace.    - A family history of cancer, including LCH.    -  Having infections as a newborn.    - Having a personal history or family history of thyroid disease.    - Smoking, especially in young adults.    - Being Hispanic.
user: What is the outlook for Langerhans Cell Histiocytosis ?

assistant: LCH in organs such as the skin, bones, lymph nodes, or pituitary gland usually gets better with treatment and is called "low- risk". LCH in the spleen, liver, or bone marrow is harder to treat and is called "high-risk".    The prognosis (chance of recovery) and treatment options depend on the following:          - Whether there are mutations of the BRAF gene.    - How old the patient is when diagnosed with LCH.    - How many organs or body systems the cancer affects.    - Whether the cancer is found in the liver, spleen, bone marrow, or certain bones in the skull.    - How quickly the cancer responds to initial treatment.    - Whether the cancer has just been diagnosed or has come back (recurred).        In infants up to one year of age, LCH may go away without treatment.
user: What are the stages of Langerhans Cell Histiocytosis ?

assistant: Key Points
                    - There is no staging system for Langerhans cell histiocytosis (LCH).    - Treatment of LCH is based on where LCH cells are found in the body and how many body systems are affected.
                
                
                    There is no staging system for Langerhans cell histiocytosis (LCH).
                    The extent or spread of cancer is usually described as stages. There is no staging system for LCH.
                
                
                    Treatment of LCH is based on where LCH cells are found in the body and how many body systems are affected.
                    LCH is described as single-system disease or multisystem disease, depending on how many body systems are affected:          -  Single-system LCH: LCH is found in one part of an organ or body system (unifocal) or in more than one part of that organ or body system (multifocal). Bone is the most common single place for LCH to be found.    -  Multisystem LCH: LCH occurs in two or more organs or body systems or may be spread throughout the body. Multisystem LCH is less common than single-system LCH.        LCH may affect low-risk organs or high-risk organs:         -  Low-risk organs include the skin, bone, lungs, lymph nodes, gastrointestinal tract, pituitary gland, and central nervous system (CNS).    -  High-risk organs include the liver, spleen, and bone marrow.