Dipak-001/mistril_dataset huggingface dataset:
user: Who is at risk for Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies? ?

assistant: The risk factors for childhood AML, childhood CML, JMML, and MDS are similar. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your childs doctor if you think your child may be at risk. These and other factors may increase the risk of childhood AML, childhood CML, JMML, and MDS:         - Having a brother or sister, especially a twin, with leukemia.    - Being Hispanic.    - Being exposed to cigarette smoke or alcohol before birth.     - Having a personal history of aplastic anemia.    - Having a personal or family history of MDS.    - Having a family history of AML.    - Past treatment with chemotherapy or radiation therapy.    - Being exposed to ionizing radiation or chemicals such as benzene.    - Having certain genetic disorders, such as:               - Down syndrome.      -  Fanconi anemia.      -  Neurofibromatosis type 1.      -  Noonan syndrome.      -  Shwachman-Diamond syndrome.
user: What are the symptoms of Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies ?

assistant: Signs and symptoms of childhood AML, childhood CML, JMML, or MDS include fever, feeling tired, and easy bleeding or bruising. These and other signs and symptoms may be caused by childhood AML, childhood CML, JMML, or MDS or by other conditions. Check with a doctor if your child has any of the following:         -  Fever with or without an infection.    - Night sweats.    - Shortness of breath.    - Weakness or feeling tired.    - Easy bruising or bleeding.    -  Petechiae (flat, pinpoint spots under the skin caused by bleeding).    - Pain in the bones or joints.    - Pain or feeling of fullness below the ribs.    - Painless lumps in the neck, underarm, stomach, groin, or other parts of the body. In childhood AML, these lumps, called leukemia cutis, may be blue or purple.    - Painless lumps that are sometimes around the eyes. These lumps, called chloromas, are sometimes seen in childhood AML and may be blue-green.    - An eczema -like skin rash.        The signs and symptoms of TMD may include the following:         - Swelling all over the body.    - Shortness of breath.    - Trouble breathing.    - Weakness or feeling tired.    - Pain below the ribs.
user: What is the outlook for Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for childhood AML depend on the following:         - The age of the child when the cancer is diagnosed.    - The race or ethnic group of the child.    - Whether the child is greatly overweight.    -  Number of white blood cells in the blood at diagnosis.    - Whether the AML occurred after previous cancer treatment.    - The subtype of AML.    - Whether there are certain chromosome or gene changes in the leukemia cells.    - Whether the child has Down syndrome. Most children with AML and Down syndrome can be cured of their leukemia.    - Whether the leukemia is in the central nervous system (brain and spinal cord).    - How quickly the leukemia responds to treatment.    - Whether the AML is newly diagnosed (untreated) or has recurred (come back) after being treated.    - The length of time since treatment ended, for AML that has recurred.        The prognosis and treatment options for childhood CML depend on how long it has been since the patient was diagnosed and how many blast cells are in the blood.   The prognosis (chance of recovery) and treatment options for JMML depend on the following:         - The age of the child when the cancer is diagnosed.    - The type of gene affected and the number of genes that have changes.    - How many red blood cells, white blood cells, or platelets are in the blood.    - Whether the JMML is newly diagnosed (untreated) or has recurred after treatment.        The prognosis (chance of recovery) and treatment options for MDS depend on the following:         - Whether the MDS was caused by previous cancer treatment.    - How low the numbers of red blood cells, white blood cells, or platelets are.    - Whether the MDS is newly diagnosed (untreated) or has recurred after treatment.
user: What are the stages of Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies ?

assistant: Key Points
                    - Once childhood acute myeloid leukemia (AML) has been diagnosed, tests are done to find out if the cancer has spread to other parts of the body.    -  There is no standard staging system for childhood AML, childhood chronic myelogenous leukemia (CML), juvenile myelomonocytic leukemia (JMML), or myelodysplastic syndromes (MDS).
                
                
                    Once childhood acute myeloid leukemia (AML) has been diagnosed, tests are done to find out if the cancer has spread to other parts of the body.
                    The following tests and procedures may be used to determine if the leukemia has spread:         -   Lumbar puncture : A procedure used to collect a sample of cerebrospinal fluid (CSF) from the spinal column. This is done by placing a needle between two bones in the spine and into the CSF around the spinal cord and removing a sample of the fluid. The sample of CSF is checked under a microscope for signs that leukemia cells have spread to the brain and spinal cord. This procedure is also called an LP or spinal tap.    -   Biopsy of the testicles, ovaries, or skin: The removal of cells or tissues from the testicles, ovaries, or skin so they can be viewed under a microscope to check for signs of cancer. This is done only if something unusual about the testicles, ovaries, or skin is found during the physical exam.
                
                
                    There is no standard staging system for childhood AML, childhood chronic myelogenous leukemia (CML), juvenile myelomonocytic leukemia (JMML), or myelodysplastic syndromes (MDS).
                    The extent or spread of cancer is usually described as stages. Instead of stages, treatment of childhood AML, childhood CML, JMML, and MDS is based on one or more of the following:          - The type of disease or the subtype of AML.    - Whether leukemia has spread outside the blood and bone marrow.    - Whether the disease is newly diagnosed, in remission, or recurrent.         Newly diagnosed childhood AML    Newly diagnosed childhood AML has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and one of the following is true:         - More than 20% of the cells in the bone marrow are blasts (leukemia cells). or    - Less than 20% of the cells in the bone marrow are blasts and there is a specific change in the chromosome.         Childhood AML in remission    In childhood AML in remission, the disease has been treated and the following are true:         - The complete blood count is almost normal.    - Less than 5% of the cells in the bone marrow are blasts (leukemia cells).    - There are no signs or symptoms of leukemia in the brain, spinal cord, or other parts of the body.
user: what research (or clinical trials) is being done for Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies ?

assistant: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Biologic therapy     Biologic therapy is a treatment that uses the patients immune system to fight cancer. Substances made by the body or made in a laboratory are used to boost, direct, or restore the bodys natural defenses against cancer. This type of cancer treatment is also called biotherapy or immunotherapy.     Natural killer (NK) cells are a type of biologic therapy. NK cells are white blood cells that can kill tumor cells. These may be taken from a donor and given to the patient by infusion to help kill leukemia cells.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: Who is at risk for Non-Small Cell Lung Cancer? ?

assistant: Smoking is the major risk factor for non-small cell lung cancer. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk to your doctor if you think you may be at risk for lung cancer.    Risk factors for lung cancer include the following:            -  Smoking cigarettes, pipes, or cigars, now or in the past. This is the most important risk factor for lung cancer. The earlier in life a person starts smoking, the more often a person smokes, and the more years a person smokes, the greater the risk of lung cancer.      -  Being exposed to secondhand smoke.     - Being exposed to radiation from any of the following:                  -  Radiation therapy to the breast or chest.       -  Radon in the home or workplace.       -  Imaging tests such as CT scans.       - Atomic bomb radiation.                 -  Being exposed to asbestos, chromium, nickel, beryllium, arsenic, soot, or tar in the workplace.     -  Living where there is air pollution.     -  Having a family history of lung cancer.     -  Being infected with the human immunodeficiency virus (HIV).     -  Taking beta carotene supplements and being a heavy smoker.           Older age is the main risk factor for most cancers. The chance of getting cancer increases as you get older.     When smoking is combined with other risk factors, the risk of lung cancer is increased.
user: What are the symptoms of Non-Small Cell Lung Cancer ?

assistant: Signs of non-small cell lung cancer include a cough that doesn't go away and shortness of breath. Sometimes lung cancer does not cause any signs or symptoms. It may be found during a chest x-ray done for another condition. Signs and symptoms may be caused by lung cancer or by other conditions. Check with your doctor if you have any of the following:         - Chest discomfort or pain.    - A cough that doesnt go away or gets worse over time.     - Trouble breathing.     - Wheezing.     -  Blood in sputum (mucus coughed up from the lungs).     - Hoarseness.     - Loss of appetite.    - Weight loss for no known reason.     - Feeling very tired.    - Trouble swallowing.    - Swelling in the face and/or veins in the neck.
user: What is the outlook for Non-Small Cell Lung Cancer ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer (the size of the tumor and whether it is in the lung only or has spread to other places in the body).    - The type of lung cancer.    - Whether the cancer has mutations (changes) in certain genes, such as the epidermal growth factor receptor (EGFR) gene or the anaplastic lymphoma kinase (ALK) gene.    - Whether there are signs and symptoms such as coughing or trouble breathing.    - The patients general health.
user: what research (or clinical trials) is being done for Non-Small Cell Lung Cancer ?

assistant: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Chemoprevention     Chemoprevention is the use of drugs, vitamins, or other substances to reduce the risk of cancer or to reduce the risk cancer will recur (come back). For lung cancer, chemoprevention is used to lessen the chance that a new tumor will form in the lung.       Radiosensitizers     Radiosensitizers are substances that make tumor cells easier to kill with radiation therapy. The combination of chemotherapy and radiation therapy given with a radiosensitizer is being studied in the treatment of non-small cell lung cancer.       New combinations    New combinations of treatments are being studied in clinical trials.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What is (are) Juvenile Myelomonocytic Leukemia ?

assistant: Key Points
                    - Juvenile myelomonocytic leukemia is a childhood disease in which too many myelocytes and monocytes (immature white blood cells) are made in the bone marrow.    - Signs and symptoms of juvenile myelomonocytic leukemia include fever, weight loss, and feeling very tired.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Juvenile myelomonocytic leukemia is a childhood disease in which too many myelocytes and monocytes (immature white blood cells) are made in the bone marrow.
                    Juvenile myelomonocytic leukemia (JMML) is a rare childhood cancer that occurs more often in children younger than 2 years. Children who have neurofibromatosis type 1 and males have an increased risk of juvenile myelomonocytic leukemia.    In JMML, the body tells too many blood stem cells to become two types of white blood cells called myelocytes and monocytes. Some of these blood stem cells never become mature white blood cells. These immature white blood cells are called blasts. Over time, the myelocytes, monocytes, and blasts crowd out the red blood cells and platelets in the bone marrow. When this happens, infection, anemia, or easy bleeding may occur.
user: What are the symptoms of Juvenile Myelomonocytic Leukemia ?

assistant: Signs and symptoms of juvenile myelomonocytic leukemia include fever, weight loss, and feeling very tired. These and other signs and symptoms may be caused by JMML or by other conditions. Check with your doctor if you have any of the following:         -  Fever for no known reason.    - Having infections, such as bronchitis or tonsillitis.    - Feeling very tired.    - Easy bruising or bleeding.    - Skin rash.    - Painless swelling of the lymph nodes in the neck, underarm, stomach, or groin.    - Pain or a feeling of fullness below the ribs.
user: What is the outlook for Juvenile Myelomonocytic Leukemia ?

assistant: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for JMML depend on the following:         - The age of the child at diagnosis.    - The number of platelets in the blood.    - The amount of a certain type of hemoglobin in red blood cells.
user: What are the treatments for Juvenile Myelomonocytic Leukemia ?

assistant: Treatment of juvenile myelomonocytic leukemia (JMML) may include the following:         -  Combination chemotherapy.    -  Stem cell transplant.    -  13-cis-retinoic acid therapy.    - A clinical trial of a new treatment, such as targeted therapy.        Check the list of NCI-supported cancer clinical trials that are now accepting patients with juvenile myelomonocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI website.
user: How to diagnose Childhood Vascular Tumors ?

assistant: Tests are used to detect (find) and diagnose childhood vascular tumors. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps, lesions, or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.     -   Ultrasound exam: A procedure in which high-energy sound waves (ultrasound) are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram. The picture can be printed to be looked at later.    -   CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.    -   MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear magnetic resonance imaging (NMRI).     -   Biopsy : The removal of cells or tissues so they can be viewed under a microscope by a pathologist to check for signs of cancer. A biopsy is not always needed to diagnose a vascular tumor.
user: what research (or clinical trials) is being done for Childhood Vascular Tumors ?

assistant: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the research process. Clinical trials are done to find out if new treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way disease will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose tumors have not gotten better. There are also clinical trials that test new ways to stop tumors from recurring (coming back) or reduce the side effects of treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
user: What causes Childhood Brain Stem Glioma ?

assistant: The cause of most childhood brain tumors is unknown.
user: Who is at risk for Childhood Brain Stem Glioma? ?

assistant: Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your child's doctor if you think your child may be at risk. Possible risk factors for brain stem glioma include:          - Having certain genetic disorders, such as neurofibromatosis type 1 (NF1).
user: What are the symptoms of Childhood Brain Stem Glioma ?

assistant: The signs and symptoms of brain stem glioma are not the same in every child. Signs and symptoms depend on the following:          - Where the tumor forms in the brain.    - The size of the tumor and whether it has spread all through the brain stem.    - How fast the tumor grows.    - The child's age and development.        Some tumors do not cause signs or symptoms. Signs and symptoms may be caused by childhood brain stem gliomas or by other conditions. Check with your child's doctor if your child has any of the following:         - Loss of ability to move one side of the face and/or body.    - Loss of balance and trouble walking.     - Vision and hearing problems.    - Morning headache or headache that goes away after vomiting.    -  Nausea and vomiting.    - Unusual sleepiness.    - More or less energy than usual.    - Changes in behavior.    - Trouble learning in school.