DevLan/vispubs huggingface dataset:
Interactive, Graph-based Visual Analysis of High-dimensional, Multi-parameter Fluorescence Microscopy Data in Toponomics
Authors: Steffen Oeltze-Jafra, Wolfgang Freiler, Reyk Hillert, Helmut Doleisch, Bernhard Preim, Walter Schubert
Published at Vis, 2011

In Toponomics, the function protein pattern in cells or tissue (the toponome) is imaged and analyzed for applications in toxicology, new drug development and patient-drug-interaction. The most advanced imaging technique is robot-driven multi-parameter fluorescence microscopy. This technique is capable of co-mapping hundreds of proteins and their distribution and assembly in protein clusters across a cell or tissue sample by running cycles of fluorescence tagging with monoclonal antibodies or other affinity reagents, imaging, and bleaching in situ. The imaging results in complex multi-parameter data composed of one slice or a 3D volume per affinity reagent. Biologists are particularly interested in the localization of co-occurring proteins, the frequency of co-occurrence and the distribution of co-occurring proteins across the cell. We present an interactive visual analysis approach for the evaluation of multi-parameter fluorescence microscopy data in toponomics. Multiple, linked views facilitate the definition of features by brushing multiple dimensions. The feature specification result is linked to all views establishing a focus+context visualization in 3D. In a new attribute view, we integrate techniques from graph visualization. Each node in the graph represents an affinity reagent while each edge represents two co-occurring affinity reagent bindings. The graph visualization is enhanced by glyphs which encode specific properties of the binding. The graph view is equipped with brushing facilities. By brushing in the spatial and attribute domain, the biologist achieves a better understanding of the function protein patterns of a cell. Furthermore, an interactive table view is integrated which summarizes unique fluorescence patterns. We discuss our approach with respect to a cell probe containing lymphocytes and a prostate tissue section.
iView: A Feature Clustering Framework for Suggesting Informative Views in Volume Visualization
Authors: Ziyi Zheng, Nafees U. Ahmed, Klaus Mueller 0001
Published at Vis, 2011

The unguided visual exploration of volumetric data can be both a challenging and a time-consuming undertaking. Identifying a set of favorable vantage points at which to start exploratory expeditions can greatly reduce this effort and can also ensure that no important structures are being missed. Recent research efforts have focused on entropy-based viewpoint selection criteria that depend on scalar values describing the structures of interest. In contrast, we propose a viewpoint suggestion pipeline that is based on feature-clustering in high-dimensional space. We use gradient/normal variation as a metric to identify interesting local events and then cluster these via k-means to detect important salient composite features. Next, we compute the maximum possible exposure of these composite feature for different viewpoints and calculate a 2D entropy map parameterized in longitude and latitude to point out promising view orientations. Superimposed onto an interactive track-ball interface, users can then directly use this entropy map to quickly navigate to potentially interesting viewpoints where visibility-based transfer functions can be employed to generate volume renderings that minimize occlusions. To give full exploration freedom to the user, the entropy map is updated on the fly whenever a view has been selected, pointing to new and promising but so far unseen view directions. Alternatively, our system can also use a set-cover optimization algorithm to provide a minimal set of views needed to observe all features. The views so generated could then be saved into a list for further inspection or into a gallery for a summary presentation.
Load-Balanced Parallel Streamline Generation on Large Scale Vector fields
Authors: Boonthanome Nouanesengsy, Teng-Yok Lee, Han-Wei Shen
Published at Vis, 2011

Because of the ever increasing size of output data from scientific simulations, supercomputers are increasingly relied upon to generate visualizations. One use of supercomputers is to generate field lines from large scale flow fields. When generating field lines in parallel, the vector field is generally decomposed into blocks, which are then assigned to processors. Since various regions of the vector field can have different flow complexity, processors will require varying amounts of computation time to trace their particles, causing load imbalance, and thus limiting the performance speedup. To achieve load-balanced streamline generation, we propose a workload-aware partitioning algorithm to decompose the vector field into partitions with near equal workloads. Since actual workloads are unknown beforehand, we propose a workload estimation algorithm to predict the workload in the local vector field. A graph-based representation of the vector field is employed to generate these estimates. Once the workloads have been estimated, our partitioning algorithm is hierarchically applied to distribute the workload to all partitions. We examine the performance of our workload estimation and workload-aware partitioning algorithm in several timings studies, which demonstrates that by employing these methods, better scalability can be achieved with little overhead.
Multi-Touch Table System for Medical Visualization: Application to Orthopedic Surgery Planning
Authors: Claes Lundström, Thomas Rydell, Camilla Forsell, Anders Persson, Anders Ynnerman
Published at Vis, 2011

Medical imaging plays a central role in a vast range of healthcare practices. The usefulness of 3D visualizations has been demonstrated for many types of treatment planning. Nevertheless, full access to 3D renderings outside of the radiology department is still scarce even for many image-centric specialties. Our work stems from the hypothesis that this under-utilization is partly due to existing visualization systems not taking the prerequisites of this application domain fully into account. We have developed a medical visualization table intended to better fit the clinical reality. The overall design goals were two-fold: similarity to a real physical situation and a very low learning threshold. This paper describes the development of the visualization table with focus on key design decisions. The developed features include two novel interaction components for touch tables. A user study including five orthopedic surgeons demonstrates that the system is appropriate and useful for this application domain.
Nodes on Ropes: A Comprehensive Data and Control Flow for Steering Ensemble Simulations
Authors: Jürgen Waser, Hrvoje Ribicic, Raphael Fuchs, Christian Hirsch, Benjamin Schindler, Günter Blöschl, M. Eduard Gröller
Published at Vis, 2011

Flood disasters are the most common natural risk and tremendous efforts are spent to improve their simulation and management. However, simulation-based investigation of actions that can be taken in case of flood emergencies is rarely done. This is in part due to the lack of a comprehensive framework which integrates and facilitates these efforts. In this paper, we tackle several problems which are related to steering a flood simulation. One issue is related to uncertainty. We need to account for uncertain knowledge about the environment, such as levee-breach locations. Furthermore, the steering process has to reveal how these uncertainties in the boundary conditions affect the confidence in the simulation outcome. Another important problem is that the simulation setup is often hidden in a black-box. We expose system internals and show that simulation steering can be comprehensible at the same time. This is important because the domain expert needs to be able to modify the simulation setup in order to include local knowledge and experience. In the proposed solution, users steer parameter studies through the World Lines interface to account for input uncertainties. The transport of steering information to the underlying data-flow components is handled by a novel meta-flow. The meta-flow is an extension to a standard data-flow network, comprising additional nodes and ropes to abstract parameter control. The meta-flow has a visual representation to inform the user about which control operations happen. Finally, we present the idea to use the data-flow diagram itself for visualizing steering information and simulation results. We discuss a case-study in collaboration with a domain expert who proposes different actions to protect a virtual city from imminent flooding. The key to choosing the best response strategy is the ability to compare different regions of the parameter space while retaining an understanding of what is happening inside the data-flow system.
Projection-Based Metal-Artifact Reduction for Industrial 3D X-ray Computed Tomography
Authors: Artem Amirkhanov, Christoph Heinzl, Michael Reiter, Johann Kastner, M. Eduard Gröller
Published at Vis, 2011

Multi-material components, which contain metal parts surrounded by plastic materials, are highly interesting for inspection using industrial 3D X-ray computed tomography (3DXCT). Examples of this application scenario are connectors or housings with metal inlays in the electronic or automotive industry. A major problem of this type of components is the presence of metal, which causes streaking artifacts and distorts the surrounding media in the reconstructed volume. Streaking artifacts and dark-band artifacts around metal components significantly influence the material characterization (especially for the plastic components). In specific cases these artifacts even prevent a further analysis. Due to the nature and the different characteristics of artifacts, the development of an efficient artifact-reduction technique in reconstruction-space is rather complicated. In this paper we present a projection-space pipeline for metal-artifacts reduction. The proposed technique first segments the metal in the spatial domain of the reconstructed volume in order to separate it from the other materials. Then metal parts are forward-projected on the set of projections in a way that metal-projection regions are treated as voids. Subsequently the voids, which are left by the removed metal, are interpolated in the 2D projections. Finally, the metal is inserted back into the reconstructed 3D volume during the fusion stage. We present a visual analysis tool, allowing for interactive parameter estimation of the metal segmentation. The results of the proposed artifact-reduction technique are demonstrated on a test part as well as on real world components. For these specimens we achieve a significant reduction of metal artifacts, allowing an enhanced material characterization.
Quasi Interpolation With Voronoi Splines
Authors: Mahsa Mirzargar, Alireza Entezari
Published at Vis, 2011

We present a quasi interpolation framework that attains the optimal approximation-order of Voronoi splines for reconstruction of volumetric data sampled on general lattices. The quasi interpolation framework of Voronoi splines provides an unbiased reconstruction method across various lattices. Therefore this framework allows us to analyze and contrast the sampling-theoretic performance of general lattices, using signal reconstruction, in an unbiased manner. Our quasi interpolation methodology is implemented as an efficient FIR filter that can be applied online or as a preprocessing step. We present visual and numerical experiments that demonstrate the improved accuracy of reconstruction across lattices, using the quasi interpolation framework.
Saliency-Assisted Navigation of Very Large Landscape Images
Authors: Cheuk Yiu Ip, Amitabh Varshney
Published at Vis, 2011

The field of visualization has addressed navigation of very large datasets, usually meshes and volumes. Significantly less attention has been devoted to the issues surrounding navigation of very large images. In the last few years the explosive growth in the resolution of camera sensors and robotic image acquisition techniques has widened the gap between the display and image resolutions to three orders of magnitude or more. This paper presents the first steps towards navigation of very large images, particularly landscape images, from an interactive visualization perspective. The grand challenge in navigation of very large images is identifying regions of potential interest. In this paper we outline a three-step approach. In the first step we use multi-scale saliency to narrow down the potential areas of interest. In the second step we outline a method based on statistical signatures to further cull out regions of high conformity. In the final step we allow a user to interactively identify the exceptional regions of high interest that merit further attention. We show that our approach of progressive elicitation is fast and allows rapid identification of regions of interest. Unlike previous work in this area, our approach is scalable and computationally reasonable on very large images. We validate the results of our approach by comparing them to user-tagged regions of interest on several very large landscape images from the Internet.
Straightening Tubular Flow for Side-by-Side Visualization
Authors: Paolo Angelelli, Helwig Hauser
Published at Vis, 2011

Flows through tubular structures are common in many fields, including blood flow in medicine and tubular fluid flows in engineering. The analysis of such flows is often done with a strong reference to the main flow direction along the tubular boundary. In this paper we present an approach for straightening the visualization of tubular flow. By aligning the main reference direction of the flow, i.e., the center line of the bounding tubular structure, with one axis of the screen, we are able to natively juxtapose (1.) different visualizations of the same flow, either utilizing different flow visualization techniques, or by varying parameters of a chosen approach such as the choice of seeding locations for integration-based flow visualization, (2.) the different time steps of a time-dependent flow, (3.) different projections around the center line , and (4.) quantitative flow visualizations in immediate spatial relation to the more qualitative classical flow visualization. We describe how to utilize this approach for an informative interactive visual analysis. We demonstrate the potential of our approach by visualizing two datasets from two different fields: an arterial blood flow measurement and a tubular gas flow simulation from the automotive industry.
Symmetry in Scalar field Topology
Authors: Dilip Mathew Thomas, Vijay Natarajan
Published at Vis, 2011

Study of symmetric or repeating patterns in scalar fields is important in scientific data analysis because it gives deep insights into the properties of the underlying phenomenon. Though geometric symmetry has been well studied within areas like shape processing, identifying symmetry in scalar fields has remained largely unexplored due to the high computational cost of the associated algorithms. We propose a computationally efficient algorithm for detecting symmetric patterns in a scalar field distribution by analysing the topology of level sets of the scalar field. Our algorithm computes the contour tree of a given scalar field and identifies subtrees that are similar. We define a robust similarity measure for comparing subtrees of the contour tree and use it to group similar subtrees together. Regions of the domain corresponding to subtrees that belong to a common group are extracted and reported to be symmetric. Identifying symmetry in scalar fields finds applications in visualization, data exploration, and feature detection. We describe two applications in detail: symmetry-aware transfer function design and symmetry-aware isosurface extraction.
The Effect of Colour and Transparency on the Perception of Overlaid Grids
Authors: Lyn Bartram, Billy Cheung, Maureen C. Stone
Published at Vis, 2011

Overlaid reference elements need to be sufficiently visible to effectively relate to the underlying information, but not so obtrusive that they clutter the presentation. We seek to create guidelines for presenting such structures through experimental studies to define boundary conditions for visual intrusiveness. We base our work on the practice of designers, who use transparency to integrate overlaid grids with their underlying imagery. Previous work discovered a useful range of alpha values for black or white grids overlayed on scatterplot images rendered in shades of gray over gray backgrounds of different lightness values. This work compares black grids to blue and red ones on different image types of scatterplots and maps. We expected that the coloured grids over grayscale images would be more visually salient than black ones, resulting in lower alpha values. Instead, we found that there was no significant difference between the boundaries set for red and black grids, but that the boundaries for blue grids were set consistently higher (more opaque). As in our previous study, alpha values are affected by image density rather than image type, and are consistently lower than many default settings. These results have implications for the design of subtle reference structures.
The FLOWLENS: A Focus-and-Context Visualization Approach for Exploration of Blood Flow in Cerebral Aneurysms
Authors: Rocco Gasteiger, Mathias Neugebauer, Oliver Beuing, Bernhard Preim
Published at Vis, 2011

Blood flow and derived data are essential to investigate the initiation and progression of cerebral aneurysms as well as their risk of rupture. An effective visual exploration of several hemodynamic attributes like the wall shear stress (WSS) and the inflow jet is necessary to understand the hemodynamics. Moreover, the correlation between focus-and-context attributes is of particular interest. An expressive visualization of these attributes and anatomic information requires appropriate visualization techniques to minimize visual clutter and occlusions. We present the FLOWLENS as a focus-and-context approach that addresses these requirements. We group relevant hemodynamic attributes to pairs of focus-and-context attributes and assign them to different anatomic scopes. For each scope, we propose several FLOWLENS visualization templates to provide a flexible visual filtering of the involved hemodynamic pairs. A template consists of the visualization of the focus attribute and the additional depiction of the context attribute inside the lens. Furthermore, the FLOWLENS supports local probing and the exploration of attribute changes over time. The FLOWLENS minimizes visual cluttering, occlusions, and provides a flexible exploration of a region of interest. We have applied our approach to seven representative datasets, including steady and unsteady flow data from CFD simulations and 4D PC-MRI measurements. Informal user interviews with three domain experts confirm the usefulness of our approach.
Topological Spines: A Structure-preserving Visual Representation of Scalar fields
Authors: Carlos D. Correa, Peter Lindstrom 0001, Peer-Timo Bremer
Published at Vis, 2011

We present topological spines-a new visual representation that preserves the topological and geometric structure of a scalar field. This representation encodes the spatial relationships of the extrema of a scalar field together with the local volume and nesting structure of the surrounding contours. Unlike other topological representations, such as contour trees, our approach preserves the local geometric structure of the scalar field, including structural cycles that are useful for exposing symmetries in the data. To obtain this representation, we describe a novel mechanism based on the extraction of extremum graphs-sparse subsets of the Morse-Smale complex that retain the important structural information without the clutter and occlusion problems that arise from visualizing the entire complex directly. Extremum graphs form a natural multiresolution structure that allows the user to suppress noise and enhance topological features via the specification of a persistence range. Applications of our approach include the visualization of 3D scalar fields without occlusion artifacts, and the exploratory analysis of high-dimensional functions.
Towards Robust Topology of Sparsely Sampled Data
Authors: Carlos D. Correa, Peter Lindstrom 0001
Published at Vis, 2011

Sparse, irregular sampling is becoming a necessity for reconstructing large and high-dimensional signals. However, the analysis of this type of data remains a challenge. One issue is the robust selection of neighborhoods - a crucial part of analytic tools such as topological decomposition, clustering and gradient estimation. When extracting the topology of sparsely sampled data, common neighborhood strategies such as k-nearest neighbors may lead to inaccurate results, either due to missing neighborhood connections, which introduce false extrema, or due to spurious connections, which conceal true extrema. Other neighborhoods, such as the Delaunay triangulation, are costly to compute and store even in relatively low dimensions. In this paper, we address these issues. We present two new types of neighborhood graphs: a variation on and a generalization of empty region graphs, which considerably improve the robustness of neighborhood-based analysis tools, such as topological decomposition. Our findings suggest that these neighborhood graphs lead to more accurate topological representations of low- and high- dimensional data sets at relatively low cost, both in terms of storage and computation time. We describe the implications of our work in the analysis and visualization of scalar functions, and provide general strategies for computing and applying our neighborhood graphs towards robust data analysis.
TransGraph: Hierarchical Exploration of Transition Relationships in Time-Varying Volumetric Data
Authors: Yi Gu, Chaoli Wang 0001
Published at Vis, 2011

A fundamental challenge for time-varying volume data analysis and visualization is the lack of capability to observe and track data change or evolution in an occlusion-free, controllable, and adaptive fashion. In this paper, we propose to organize a timevarying data set into a hierarchy of states. By deriving transition probabilities among states, we construct a global map that captures the essential transition relationships in the time-varying data. We introduce the TransGraph, a graph-based representation to visualize hierarchical state transition relationships. The TransGraph not only provides a visual mapping that abstracts data evolution over time in different levels of detail, but also serves as a navigation tool that guides data exploration and tracking. The user interacts with the TransGraph and makes connection to the volumetric data through brushing and linking. A set of intuitive queries is provided to enable knowledge extraction from time-varying data. We test our approach with time-varying data sets of different characteristics and the results show that the TransGraph can effectively augment our ability in understanding time-varying data.