Question: Minkowski and von Mering did surgical tests on what animal?
Answer: dogs

Question: What is phenobarbital used for?
Answer: epilepsy

Question: Who discovered a reaction that induced sleep in dogs?
Answer: Hermann Emil Fischer and Joseph von Mering

Question: What sleep aid was marketed in 1904?
Answer: Veronal

Question: What is amphetamine used for today?
Answer: attention deficit disorder

Question: Why was barbiturates and amphetamines restricted?
Answer: addictive properties and abuse potential

Question: What compound was discovered to induce sleep?
Answer: diethylbarbituric acid

Question: What was the first trade name of diethylbarbituric acid?
Answer: Veronal

Question: What is phenobarbital mainly used to treat today?
Answer: epilepsy

Question: In what year was phenobarbital discovered?
Answer: 1911

Question: What was Veronal used for when Bayer put it on the market?
Answer: sleep aid

Question: Who developed Arsphenamine?
Answer: Paul Ehrlich and chemist Alfred Bertheim

Question: What was the first effective treatment for Syphilis?
Answer: Arsphenamine

Question: What complications are associated with Syphilis?
Answer: severe skin ulceration, neurological damage, and death

Question: What is Amphetamine's market name?
Answer: Institute of Experimental Therapy

Question: Where is the Institute of Experimental Therapy located?
Answer: Berlin

Question: Bacterial infections could be treated with medicines containing what kind of dye?
Answer: arsenic

Question: What was the name of the first synthetic bacterial drug?
Answer: arsphenamine

Question: Arsphenamine became the first treatment for what previously incurable disease?
Answer: syphilis

Question: In what year was arsphenamine discovered?
Answer: 1911

Question: What was the commercial name of arsphenamine?
Answer: Salvarsan

Question: When was Morphine and Quinine first available?
Answer: mid 1800s

Question: Who was the compound named after?
Answer: Morpheus

Question: Who came up with the name Morphine?
Answer: Friedrich Sertürner

Question: Where were was Morphine extracted from?
Answer: opium

Question: Who is responsible for purification of compounds found in mineral sources?
Answer: German dye manufacturers

Question: Morphine was named after what Greek god?
Answer: Morpheus

Question: Burroughs-Wellcome is now part of what medical company?
Answer: Glaxo Smith Kline

Question: Who discovered morphine?
Answer: Friedrich Sertürner

Question: What is the name of the plant that produces morphine?
Answer: opium

Question: Who received the Nobel Prize in Medicine in 1939?
Answer: Gerhard Domagk

Question: Prontosil is in what drug class?
Answer: antibiotics

Question: Who is responsible for creating Prontosil?
Answer: Josef Klarer, Fritz Mietzsch, and Gerhard Domagk

Question: What causes Streptococci?
Answer: pathogens

Question: Many deaths occurred before World War II due to what?
Answer: infectious diseases

Question: What was the name of the first sulfonamine antibiotic?
Answer: Prontosil

Question: What award did Domagk receive in 1939?
Answer: Nobel Prize in Medicine

Question: Anti-infective drugs became more prominent after what war?
Answer: World War II

Question: Were sulfonamides more or less toxic than arsphenamine?
Answer: less

Question: Streptococci and other pathogens could be treated by what type of antibiotics?
Answer: sulfonamides

Question: Who created the first rabies vaccine?
Answer: Louis Pasteur and Pierre Paul Émile Roux

Question: How many cases of Diphtheria were there in 1921?
Answer: 206,000

Question: In 1923, what was discovered to be safer to treat Diphtheria Toxin?
Answer: formaldehyde

Question: Who created a vaccine to treat Japanese Encephalitis?
Answer: Maurice Hilleman

Question: How many deaths occurred due to Diphtheria?
Answer: 15,520

Question: The rabies vaccine was created in what year?
Answer: 1885

Question: In what year was the diphtheria vaccine made?
Answer: 1914

Question: What compound made the diphtheria vaccine safer to use?
Answer: formaldehyde

Question: Who developed the first encephalitis vaccine? 
Answer: Maurice Hilleman

Question: What company did Hilleman later work for?
Answer: Merck

Question: Who manufactured "Elixir Sulfanilamide"?
Answer: S.E. Massengill Company

Question: What was one of the things the Federal Food, Drug and Cosmetic Act do?
Answer: explicitly prohibited false therapeutic claims

Question: What year did Congress pass the Federal Food, Drug, and Cosmetic Act?
Answer: 1938

Question: What drug killed 100 people in 1937?
Answer: Elixir Sulfanilamide

Question: What is Diethylene Glycol commonly used for now?
Answer: antifreeze

Question: What company manufactured Elixir Sulfanilamide? 
Answer: S.E. Massengill Company of Tennessee

Question: What drug killed over 100 people in 1937?
Answer: Elixir Sulfanilamide

Question: Diethylene glycol is mainly used today as what liquid?
Answer: antifreeze

Question: What law did Congress pass following the Elixir Sulfanilamide incident?
Answer: Federal Food, Drug, and Cosmetic Act of 1938

Question: The name "elixir" implied a solution in what liquid?
Answer: ethanol

Question: When was the first effective treatment for Tuberculosis discovered?
Answer: 1943

Question: 50% of tuberculosis-infected people died within 5 years where?
Answer: cities in developed countries

Question: What drug effectively treated Tuberculosis?
Answer: Streptomycin

Question: Who was Eli Lilly's work based off of?
Answer: Giuseppe Brotzu and Edward Abraham

Question: Where was Tetracyclines discovered?
Answer: Lederle Laboratories

Question: What was the first treatment for tuberculosis?
Answer: Streptomycin

Question: What percentage of patients infected with tuberculosis died within 5 years?
Answer: 50%

Question: In what year was streptomycin discovered?
Answer: 1943

Question: Many more antibiotics were made following the end of what war?
Answer: World War II

Question: What company funded the research that led to the discovery of streptomycin?
Answer: Merck

Question: When was the Polio vaccine created?
Answer: 1954

Question: Who announced that SV40 was not associated with cancer?
Answer: United States Cancer Institute

Question: Who identified the SV40 virus?
Answer: Maurice Hilleman

Question: What was a complication of the SV40 virus?
Answer: cause tumors

Question: Who funded the Polio vaccine?
Answer: National Foundation for Infantile Paralysis

Question: In what year was the polio vaccine created?
Answer: 1954

Question: Who created the polio vaccine?
Answer: Jonas Salk

Question: What virus caused tumors in most mammals?
Answer: SV40

Question: SV40 was present in what vaccine?
Answer: polio

Question: How much was the settlement GlaxoSmithKline agree to?
Answer: $3 billion

Question: What was one of the causes of the health-care fraud case?
Answer: illegal promotion of prescription drugs

Question: When did GlaxoSmithKline plead guilty?
Answer: 2 July 2012

Question: What drugs were related to a kickback scheme?
Answer: Imitrex, Lotronex, Flovent, and Valtrex

Question: What drugs were used for off-label uses?
Answer: Paxil, Wellbutrin, Advair, Lamictal, and Zofran

Question: In what year did GlaxoSmithKline pay a $3 billion dollar settlement?
Answer: 2012

Question: How much was the largest healthcare fraud case in the US settled for?
Answer: $3 billion

Question: What company was sued for promoting medicines for unlicensed uses and bribing doctors?
Answer: GlaxoSmithKline

Question: What is the speculation of the relationship between doctors and the drug industry?
Answer: become fully transparent.

Question: What is the Physician Financial Transparency Report part of?
Answer: Sunshine Act

Question: Where can you obtain information about the Sunshine Act?
Answer: Centers for Medicare & Medicaid Services website

Question: What information is collected by Centers for Medicine & Medicaid Services?
Answer: financial relationships with physicians and hospitals.