Neuroimaging and electrophysiological studies of the effects of acute tryptophan depletion: a systematic review of the literature.

There is a growing psychopharmacological literature on the use of Acute Tryptophan Depletion (ATD) for experimental modulation of the serotonergic system. To date, no systematic review has been undertaken assessing the neurophysiological effects following this acute central 5-HT manipulation.