A systematic review and meta-analysis of anti-adhesion molecule therapy in patients with active Crohn's disease.

Due to the crucial role played by adhesion molecules in the pathogenesis of Crohn's disease (CD), targeting of these molecules has recently been proposed as a new direction for the development of anti-inflammatory strategies for CD. The aim of this study was to provide up-to-date evidence on the effectiveness and safety of anti-adhesion molecule therapy in treating active CD.