Effect of antihypertensive agents on risk of atrial fibrillation: a meta-analysis of large-scale randomized trials.

High blood pressure is known to be associated with future risk of atrial fibrillation. Whether such risks can be reduced with antihypertensive therapy is less clear. We conducted a systematic review and meta-analysis of large-scale randomized trials that have reported the effect of antihypertensive agents on atrial fibrillation.