Data-Gouv-ML/pcri-erc-participations-et-projets-laureats huggingface dataset:
Projet ERC : EPHEMERAL (Horizon 2020, appel 2019, Advanced grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Earth system science
Entité participante : Centre national de la recherche scientifique — Pays : France — Rôle : Partner
Acronyme de l'entité : CNRS
Type d'entité : Recherche
Financement ERC de l'entité : 0.0 €

Earth’s lower atmosphere is oxidative and its chemistry consists of reactions of short-lived chemical compounds called radicals, controlling the abundance of key compounds, such as of ozone and greenhouse gases. In spite of decades of investigation many atmospheric observations indicate that important aspects of this radical chemistry remain ill-understood, in particular in the reactions of the multitude of organic radicals present in the atmosphere, peroxy radicals (“RO2”) and Criegee Intermediates (“CI”). Detailed investigations of these reactions have been limited for over 50 years by instrumental challenges, in particular by the lack of technique detecting individual radicals (”speciation”). Recently, the Nozière group achieved an important milestone by developing the first technique, based on Chemical Ionization Mass Spectrometry or “CIMS”, speciating the volatile RO2 that are important for the atmospheric oxidation cycles. The objective of EPHEMERAL is to solve key questions in atmospheric radical chemistry by overcoming the long-standing instrumental challenges with cutting-edge developments based on this new technique. Three strategic directions will be pursued: - in laboratory, the detection of CI will be investigated and gas-phase reactions of RO2 and CI studied, - an instrument will be built to detect individual RO2 and CI in the atmosphere, thus achieving a historical milestone, - the reactivity of these radicals at/with surfaces will be investigated in laboratory, assessing for the first time the role of clouds and aerosols in the oxidation cycles and setting the bases for next-generation challenges. The fundamental knowledge and atmospheric observations resulting from this project will dramatically improve the understanding of the oxidation cycles and the predictions of the atmospheric chemical composition, from the regional to the climate scale. EPHEMERAL will thus place Europe at the leading edge in the discipline, scientifically and technologically.
Projet ERC : SEPtiM (Horizon 2020, appel 2020, Advanced grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Earth system science
Entité participante : Centre national de la recherche scientifique — Pays : France — Rôle : PI
Acronyme de l'entité : CNRS
Type d'entité : Recherche
Financement ERC de l'entité : 2254250.0 €

Earth’s mantle was extensively molten in its first 100 million years. Its solidification left a strong compositional and structural imprint on the mantle, still observable today in the geochemical and geophysical record. Isotopic variations in basalts and ancient crust reveal the existence of one or more mantle reservoirs that formed early in Earth’s history, and never fully remixed. Seismic tomography reveals large, chemically distinct, thermochemical structures in the lowermost mantle, anchored to the source of these anomalous basalts. These observations leave no doubt that the mantle still bears differentiated regions that preserve signatures of its solidification. However, their formation mechanisms and compositional evolution are still unknown. Unravelling those opens a new window in understanding the early stages of Earth and planetary evolution. The overarching question of this proposal: how did the primitive molten Earth solidify to form a tectonically and geomagnetically active planet? My goal is to address this question by investigating mantle crystallisation in the laboratory, by combining experimental petrology, thermodynamical modelling, and geodynamical simulations in a self-consistent fashion. I propose to assemble a multidisciplinary team to: (1) experimentally study the crystallisation sequence of relevant silicate melts in the laboratory under P-T conditions extending to those at of the depth of the core-mantle boundary, using a newly developed protocol in the laser-heated diamond anvil cell; (2) use these results to constrain a thermodynamical model of phase relations and compositions, and trace-element partitioning between solids and melts; (3) use DFT calculations to calculate the density and relative buoyancy of these solids and melts; (4) feed the thermodynamics and buoyancy as input to mushy two-phase 3D fluid dynamics simulations, to realistically simulate the dynamical and thermochemical evolution of Earth’s mantle as it solidified.

Mots-clés : experimentation at high pressure and temperature,ab initio calculations,thermodynamic modelling,geodynamical modelling
Projet ERC : KaraimBible (Horizon 2020, appel 2018, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Cultures and cultural production
Entité participante : Jagiellonian University — Pays : Pologne — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1187325.0 €

Eastern European Karaims are the sole representatives of Karaite Judaism in Europe. Their native tongue is a severely endangered Turkic vernacular listed on the UNESCO Atlas of the Worlds’ Languages in Danger. Due to many historical events, including World War II and the Soviet era, the cultural heritage of this intriguing ethnic minority suffered great losses. At the same time, since its investigation requires a rare combination of unique linguistic and palaeographic skills merely a fraction of its surviving written heritage has entered scholarly circulation. In particular, no comprehensive edition of the Karaim Hebrew Bible exists, even though nearly 100 Karaim Biblical texts have been discovered to date. The project will construct a digital edition of the entire Karaim Bible, almost exclusively based on unedited texts in Hebrew script (15th–20th cc). It will be used as a tool to deliver the first linguistic and palaeographic descriptions of the oldest, still unedited records of Karaim as well as reconstruct the way in which the Karaim Bible was created. Combining traditional and computer-aided research methods will provide essential data on the early history of the Karaim language and ethnicity. The edition will be a highly complex instrument interconnected with a dictionary, which is an absolute novelty in the field. The edition will contain the first ever comprehensive Karaim translation intelligible to present-day native-speakers. The texts will be treated according to the principles of textual criticism and translated into English. If permitted, facsimiles will be provided. One exciting aspect of the enterprise is that it will offer a virtual unification of the Karaim translations of one of the most important and influential works in world literature. Such a task is of fundamental importance and is crucial to sustaining an endangered culture, given that an awareness of the oldest Bible translations is an important component of European national identities.

Mots-clés : turkology,textual criticism,cultural heritage of endangered languages
Projet ERC : NormativeEconomics (Horizon 2020, appel 2014, Advanced grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Individuals, Markets and Organisations
Entité participante : University of Warwick — Pays : Royaume-Uni — Rôle : Partner
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 178757.56 €

Economics has traditionally assumed that individuals seek to satisfy coherent and asocial preferences, and has used the satisfaction of those preferences as a normative criterion. This ‘neoclassical’ approach has supported a view of the market as an institution in which privately-motivated individual actions tend to produce socially beneficial consequences. These ideas have been called into question by recent developments in behavioural economics, which point to the cognitive limitations of economic agents, the instability of preferences, and the existence of pro-social motivations. A common inference is that traditional presumptions in favour of the market and against paternalism are invalidated. I aim to develop an approach to normative economics, and a corresponding understanding of the role of markets, which do not require neoclassical rationality assumptions but may still support those presumptions. My approach is innovative in two ways. First, the criterion for normative analysis is opportunity, not preference satisfaction. Even if individuals lack coherent preferences, opportunities for mutually advantageous transactions can be defined in a normatively significant way, and competitive markets can be shown to be effective in providing such opportunities. Second, using a new version of the theory of ‘team reasoning’, the relationship between parties to a market transaction can be construed in terms of a joint intention to achieve mutual benefit. This motivation can support practices of trust and cooperation without disabling market incentives. Using the methods of theoretical and experimental economics and analytical philosophy, I will formalise and integrate these ideas and extend them to provide a new understanding of the role of government in the economy. This work will include analyses of distributional fairness, market ethics, and of the role of regulation in maintaining competitive markets in the face of consumers’ cognitive limitations.

Mots-clés : normative economics,behavioural economics,opportunity,team reasoning,mutual advantage
Projet ERC : MOREV (Horizon 2020, appel 2019, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Individuals, Markets and Organisations
Entité participante : Fondation nationale des sciences politiques — Pays : France — Rôle : Partner
Acronyme de l'entité : FNSP
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 75000.0 €

Economists have distinguished for long soft and hard information with the understanding that cheap talk is more prone to subjective interpretation than hard evidence. In fact, any piece of evidence carries some of the true underlying information that agents are usually assumed to be willing and able to access. For various reasons, agents may however prefer to avoid disturbing truths or maintain wrong but encouraging beliefs. In MOREV, I propose to study motivated reading of evidence, that is, study how individuals interpret hard information in ways that serve their own purposes. I wish to identify the goals that push the reading of evidence in systematic ways. I also want to study how agents manage to distort this reading, for example by choosing not to read or reason about available evidence. The MOREV project is divided into two parts, each bringing the recent literature on motivated beliefs to a new area of study. In part 1, I will focus on agents' motivated reading of evidence about other individuals (their ability, their socio-economic characteristics, etc.). Indeed, one may not view a person the same way ahead of cooperative or competitive tasks. It is well-established that how close agents feel to each other (as network members or in terms of social identity) affects what they do to each other. I propose to investigate experimentally and theoretically the converse relationship: how do agents’ strategic goals affect their perception of others? In part 2, I will focus on agents' motivated reading of evidence about products. For example, consumers may purposefully distort their beliefs about some attributes to make their purchasing plans easier to execute or take on. To do so, agents may not interpret vague information skeptically or, more generally, use motivated reasoning processes. By studying these ideas in the lab and in new models, I aim at bringing a novel explanation to the fact that, in many markets, information does not unravel as theory predicts./

Mots-clés : motivated beliefs,hard information,disclosure games
Projet ERC : GATIPOR (Horizon 2020, appel 2014, Consolidator grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Mathematics
Entité participante : Institut national de recherche en sciences et technologies du numérique — Pays : France — Rôle : PI
Acronyme de l'entité : Inria
Type d'entité : Recherche
Financement ERC de l'entité : 1283087.5 €

Efficient use of computational resources with a reliable outcome is a definite target in numerical simulations of partial differential equations (PDEs). Although this has been an important subject of numerical analysis and scientific computing for decades, still, surprisingly, often more than 90% of the CPU time in numerical simulations is literally wasted and the accuracy of the final outcome is not guaranteed. The reason is that addressing this complex issue rigorously is extremely challenging, as it stems from linking several rather disconnected domains like modeling, analysis of PDEs, numerical analysis, numerical linear algebra, and scientific computing. The goal of this project is to design novel inexact algebraic and linearization solvers, with each step being adaptively steered by optimal (guaranteed and robust) a posteriori error estimates, thus online interconnecting all parts of the numerical simulation of complex environmental porous media flows. The key novel ingredients will be multilevel algebraic solvers, tailored to porous media simulations, with problem- and discretization-dependent restriction, prolongation, and smoothing, yielding mass balance on all grid levels, accompanied by local adaptive stopping criteria. We shall theoretically prove the convergence of the new algorithms and justify their optimality, with in particular guaranteed (without any unknown constant) error reduction and overall computational load. Implementation into established numerical simulation codes and assessment on renowned academic and industrial benchmarks will consolidate the theoretical results. As a final outcome, the total simulation error will be certified and current computational burden cut by orders of magnitude. This would represent a cardinal technological advance both theoretically as well as practically in urgent environmental applications, namely the nuclear waste storage and the geological sequestration of CO2.

Mots-clés : multigrid method,inexact solver,adaptive steering,local stopping criterion,a posteriori error estimate,robustness,convergence,optimality,porous media flow,environmental application
Projet ERC : PROTECT (Horizon 2020, appel 2020, Consolidator grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Synthetic Chemistry and Materials
Entité participante : Eindhoven University of Technology — Pays : Pays-Bas — Rôle : PI
Acronyme de l'entité : TU/e
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1999535.0 €

Efficient, non-toxic cryoprotectants, that allow long-term storage of viable therapeutic cells and tissues, are the tool that regenerative medicine requires for its successful realization into a viable therapeutic option. A remarkable class of biopolymers known as ice-binding proteins (IBPs) alleviate the risk of freeze injury throughout the Kingdoms of Life by keeping the nucleation and growth of ice crystals in check. Yet, the application potential of IBP analogues (IBPAs) as cryoprotectants has remained underexploited. This is because we are yet to unravel and utilize the structure-function relations, which govern the activity of IBPAs as inhibitors of ice recrystallization and promoters of ice nucleation at the single-molecule level in vitro and within a complex biological environment. I propose to develop uniquely modular IBPAs to perform the quantitative single-molecule and physico-chemical experiments essential to bridge this knowledge gap and to engineer ice-binders optimized for cryopreservation. Our first aim is the biosynthesis of a novel class of ice-binding protein-polymers (iPP) with systematic variations in composition and size. Ice nucleators with a broad range of sizes will be created from iPPs of variable chain length by dissolution, self-assembly and surface-tethering to nanoparticles of variable dimensions. Super-resolution microscopy experiments of iPP ice-binding will deliver high-resolution maps of spatiotemporal distribution and dynamics. These will be related to iPP structure, physico-chemical properties, ice recrystallization inhibition (IRI) and ice nucleation (IN) activity. These insights will translate into the next generation of bioactive iPPs tailored to maximize both IRI and IN. Their impact on heart cell and tissue cryopreservation will be examined to advance our fundamental understanding of freeze injury and dramatically improve post-thaw recovery as well as structural and functional integrity without adverse effects.

Mots-clés : soft matter,protein polymers,ice nucleation,ice binding,cryopreservation,cardiomyocytes,single molecule localization microscopy,self assembly,biopolymers,antifreeze proteins,single molecule dynamics,ice recrystallization inhibition,thermal hysteresis,protein engineering
Projet ERC : MEET (Horizon 2020, appel 2019, Synergy grants)
Entité participante : Helmholtz Centre Potsdam - GFZ German Research Centre for Geosciences — Pays : Allemagne — Rôle : PI
Acronyme de l'entité : GFZ
Type d'entité : Recherche
Financement ERC de l'entité : 2767343.75 €

Efforts to reconstruct the early Earth evolution lack critical information on the contents of mobile and volatile elements and their isotope signatures in the mantle and crust. Fortunately, this information is preserved in inclusions of melt in relicts of olivine from komatiites and picrites, and zircons from mafic and felsic rocks. In Aim I, we will use compositions and temperatures of primary mantle-derived melts reconstructed from the study of melt inclusions in olivine from komatiites and picrites to constrain the evolution of mantle composition. We will further study crust-formation, crust-mantle recycling, and crust-hydrosphere exchange based on composition of melt inclusions and host zircons. We will analyse a wide range of volatile elements and their isotopes in homogenized melt inclusions and the elemental and isotopic compositions of host olivines and zircons. The samples come from 24 localities of komatiites and picrites originating at different cratons between 3.7 and 0.06 Ga, and detrital and magmatic zircons with ages from 4.4 Ga to present. We will apply published and new models to constrain the temperatures and compositions of mantle and crustal sources. In Aim II, geodynamic modelling will relate our observations to the evolution of mantle convection, crustal production and recycling, and plate tectonics (PT). We will couple geodynamic modelling with surface and climate models and use derived geochemical proxies to test our hypotheses on the importance of surface processes in evolution of PT. We will thus address several fundamental issues: the rate of crustal growth and recycling through time; the cause and timing of the onset of large-scale subduction and PT, and factors controlling its evolution; concentration and origin of H2O and halogens in the deep mantle, and the extent (if any) of core-mantle interaction. MEET will, therefore, offer an unprecedented look at the evolution of Earth from 4.4 Ga to today, and from the atmosphere to the core.

Mots-clés : earth mantle,earth crust,geodynamics,melt inclusions,olivine,zircon,spinel
Projet ERC : MEET (Horizon 2020, appel 2019, Synergy grants)
Entité participante : Université Grenoble Alpes — Pays : France — Rôle : CO-PI
Acronyme de l'entité : UGA
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 6348405.0 €

Efforts to reconstruct the early Earth evolution lack critical information on the contents of mobile and volatile elements and their isotope signatures in the mantle and crust. Fortunately, this information is preserved in inclusions of melt in relicts of olivine from komatiites and picrites, and zircons from mafic and felsic rocks. In Aim I, we will use compositions and temperatures of primary mantle-derived melts reconstructed from the study of melt inclusions in olivine from komatiites and picrites to constrain the evolution of mantle composition. We will further study crust-formation, crust-mantle recycling, and crust-hydrosphere exchange based on composition of melt inclusions and host zircons. We will analyse a wide range of volatile elements and their isotopes in homogenized melt inclusions and the elemental and isotopic compositions of host olivines and zircons. The samples come from 24 localities of komatiites and picrites originating at different cratons between 3.7 and 0.06 Ga, and detrital and magmatic zircons with ages from 4.4 Ga to present. We will apply published and new models to constrain the temperatures and compositions of mantle and crustal sources. In Aim II, geodynamic modelling will relate our observations to the evolution of mantle convection, crustal production and recycling, and plate tectonics (PT). We will couple geodynamic modelling with surface and climate models and use derived geochemical proxies to test our hypotheses on the importance of surface processes in evolution of PT. We will thus address several fundamental issues: the rate of crustal growth and recycling through time; the cause and timing of the onset of large-scale subduction and PT, and factors controlling its evolution; concentration and origin of H2O and halogens in the deep mantle, and the extent (if any) of core-mantle interaction. MEET will, therefore, offer an unprecedented look at the evolution of Earth from 4.4 Ga to today, and from the atmosphere to the core.

Mots-clés : earth mantle,earth crust,geodynamics,melt inclusions,olivine,zircon,spinel
Projet ERC : MEET (Horizon 2020, appel 2019, Synergy grants)
Entité participante : University of Wisconsin System — Pays : Etats-Unis — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 3229854.0 €

Efforts to reconstruct the early Earth evolution lack critical information on the contents of mobile and volatile elements and their isotope signatures in the mantle and crust. Fortunately, this information is preserved in inclusions of melt in relicts of olivine from komatiites and picrites, and zircons from mafic and felsic rocks. In Aim I, we will use compositions and temperatures of primary mantle-derived melts reconstructed from the study of melt inclusions in olivine from komatiites and picrites to constrain the evolution of mantle composition. We will further study crust-formation, crust-mantle recycling, and crust-hydrosphere exchange based on composition of melt inclusions and host zircons. We will analyse a wide range of volatile elements and their isotopes in homogenized melt inclusions and the elemental and isotopic compositions of host olivines and zircons. The samples come from 24 localities of komatiites and picrites originating at different cratons between 3.7 and 0.06 Ga, and detrital and magmatic zircons with ages from 4.4 Ga to present. We will apply published and new models to constrain the temperatures and compositions of mantle and crustal sources. In Aim II, geodynamic modelling will relate our observations to the evolution of mantle convection, crustal production and recycling, and plate tectonics (PT). We will couple geodynamic modelling with surface and climate models and use derived geochemical proxies to test our hypotheses on the importance of surface processes in evolution of PT. We will thus address several fundamental issues: the rate of crustal growth and recycling through time; the cause and timing of the onset of large-scale subduction and PT, and factors controlling its evolution; concentration and origin of H2O and halogens in the deep mantle, and the extent (if any) of core-mantle interaction. MEET will, therefore, offer an unprecedented look at the evolution of Earth from 4.4 Ga to today, and from the atmosphere to the core.

Mots-clés : earth mantle,earth crust,geodynamics,melt inclusions,olivine,zircon,spinel