Data-Gouv-ML/pcri-erc-participations-et-projets-laureats huggingface dataset:
Projet ERC : HYIHY (Horizon Europe, appel 2025, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Soci al World and Its Interactions
Entité participante : Université Friedrich-Alexander d'Erlangen-Nuremberg — Pays : Allemagne — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1498940.0 €

The HYIHY project investigates how HYbrid Interactions—blending face-to-face, digital, and human-AI communication—reshape social well-being in HYbrid work. To answer this, I propose communication episodes, their quality, and technological context as a unified lens. Through this lens, we can understand how complex sequences of face-to-face, digital, and AI interactions impact our sense of loneliness, connectedness, and community (i.e., social well-being). Ultimately aimed at formulating a Hybrid Interaction Theory (HIT), the project will dramatically move research beyond siloed insights from communication, psychology, human-computer interaction, sociotechnical studies, and public health. Social connection is essential for human health and well-being—and the work domain is essential for adults to feel socially connected. Two interrelated trends currently redefine adults’ social well-being: hybrid work, blending office and remote work, and the increasing digitalization of sociality described by hybrid interactions. UN, EU, UK, and US institutions have voiced serious concerns over a post-pandemic ‘loneliness epidemic’ in this new world of work, yet evidence on how workers can maintain their social well-being is severely limited.  Three questions guide this project: (1) How do the various communication episodes in hybrid work shape social well-being? (2) How do digital channels and artificially intelligent (AI) interlocutors moderate these effects? (3) Which beneficial or harmful dynamics between face-to-face, digital, and human-AI communication episodes unfold in workers’ daily lives? To answer these questions and test multiple competing hypotheses, HYIHY combines qualitative, panel, experience sampling, experimental, and computational methods in a comprehensive work program. Informed by my findings, workers and stakeholders in labor unions, industry, and policy are well positioned to design, manage, and regulate hybrid and digitalized sociality in the future of work.

Mots-clés : social media,interpersonal communication,digital communication,human machine communication,media psychology,social connection,social well being,loneliness,remote work,work from home,hybrid work,future of work
Projet ERC : MAGERY (Horizon Europe, appel 2023, Starting grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Products and Processes Engineering
Entité participante : Université Friedrich-Alexander d'Erlangen-Nuremberg — Pays : Allemagne — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 2229523.0 €

This project aims at revolutionising the treatment of brain disorders through mechanics-augmented brain surgery (MAGERY). Due to the ultrasoft nature of brain tissue, surgical procedures have exceptionally high requirements for minimal invasiveness and maximal safety. During the procedure, brain tissue largely deforms and is easily loaded beyond its functional tolerance. A promising technology to improve surgical outcomes is to integrate virtual information either through immersed virtual reality (VR) in training and planning or through augmented reality (AR) overlaying virtual information with the surgeon’s real view. Despite rapid advances, to date, most VR/AR solutions have disregarded the complex region-dependent mechanical properties of brain tissue and mechanics-induced cell dysfunction or death. The MAGERY project will follow a new paradigm by focusing on brain mechanics. We imply that we can minimise unnecessary brain tissue damage by integrating continuum mechanics-based simulations into VR/AR solutions. Realising this objective will require to combine state-of-the-art approaches in live cell imaging, nonlinear continuum mechanics, and computational engineering. The applicant and the MAGERY team will for the first time perform simultaneous large-strain mechanical measurements and multiphoton microscopy, and, through modelling and simulations, identify thresholds for tissue and cell damage under complex three-dimensional loadings. By merging simulation results and VR/AR techniques, this project strives towards real-time predictions of brain tissue deformation and corresponding damage. With her pioneering role in testing and modelling the complex behaviour of human brain tissue, the applicant has excellent prerequisites to tackle these challenges.  If successful, this project can not only revolutionise VR/AR for brain surgery, but also leverage our understanding of the cellular response to three-dimensional mechanical loading across length and time scales.

Mots-clés : biomechanics,nonlinear continuum mechanics,finite element modeling,brain mechanics,brain surgery
Projet ERC : VIRTUTRIALS (Horizon Europe, appel 2024, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Soci al World and Its Interactions
Entité participante : Université de Lund — Pays : Suède — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1500000.0 €

Video links are widely used in courtrooms across the globe but there is a mounting apprehension that the legitimacy and fairness of trials are threatened by the diminishment of physical interactions this format entails. The problem addressed in VIRTUTRIALS is that current concerns regarding the threat video links pose to trials by diminishing physical interaction may not be substantiated by contemporary examination. Instead, these concerns may originate from a fetishization of physicality, despite physicality remaining an enigma. Given the centrality and importance of trials in democratic societies, this has important implications for legal security and the continued trust in the legal system. It is especially critical considering the impending shift to virtual reality trials devoid of physical presence.  VIRTUTRIALS will identify how physicality and the absence thereof shapes contemporary trials and participation within in order to show if and how trials can retain their legitimacy and fairness in virtual settings. The state-of-the-art pinpoints three interlinked themes regarding physicality which inspire the research questions:  RQ1: How does participation format shape participants’ accomplishment and experience? RQ2: What are the social ingredients of virtual justice rituals? RQ3: How are displays of credibility and remorse understood and evaluated in physical versus virtual trials?  VIRTUTRIALS has an innovative abductive and interconnected design using a multi-methods approach, including ethnography, qualitative interviews, and a combined qualitative and quantitative analysis of written judgements. By uniquely drawing on a social scientific perspective with interactionist theory, it aims to analyse and challenge the current understanding of trials as face-to-face interactions. In today’s rapidly digitalising world, where interactions in virtual settings are progressively prevalent and intricate, VIRTUTRIALS contributes vital knowledge on virtual interactions.

Mots-clés : video links,physicality,virtual participation,emotion,ritual,interactions,trials,practices
Projet ERC : IDOL (Horizon Europe, appel 2021, Starting grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Materials Engineering
Entité participante : Université technique du Danemark — Pays : Danemark — Rôle : PI
Acronyme de l'entité : DTU
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 2263750.0 €

Progress in sustainable energy technology relies on the discovery of new earth-abundant materials with unprecedented ability to conduct ions, catalyze reactions, transport photogenerated carriers, etc. The main scientific question is how to find the materials with exactly the desired functionality from the huge pool of all possible materials (more than 10^12).  In IDOL, we will attempt to answer the long-standing question of inverse materials design. Our targeted functionality is high optoelectronic quality (i.e., long photocarrier lifetimes, high mobilities, and high absorption coefficient) in an earth-abundant semiconductor with band gap above 1.5 eV. This will be a breakthrough in three areas key to a sustainable energy future: multijunction photovoltaics, light-emitting diodes, and solar fuels.  The IDOL approach is a combination of experimental and computational research, focusing on the most device-relevant material form: thin films. Initially, we will restrict our search to the intriguing and still highly underexplored family of phosphosulfides (PSs). Later, we will extend our insights to other chemistries. From my preliminary investigation, many PSs should exhibit high mobilities and appropriate band gaps.  We will break the inverse design problem into logically connected steps: from application-specific figures of merit, going back to defect properties, generic optoelectronic properties, structure, growth conditions, and composition. We will exploit a unique combinatorial deposition system to grow candidate materials and characterize them using high throughput facilities at our host. For properties not experimentally accessible, we will employ first-principles calculations. This hybrid dataset will be analyzed step-by-step by human intelligence and machine learning to formulate design criteria and generate new materials with the desired properties. The discovered PS with the highest figures of merit will be incorporated into an actual photovoltaic device.

Mots-clés : optoelectronics,photovoltaics,phosphides,sulfides,high throughput experiments
Projet ERC : ChemBioChol (Horizon Europe, appel 2021, Starting grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Synthetic Chemistry and Materials
Entité participante : Université technique du Danemark — Pays : Danemark — Rôle : PI
Acronyme de l'entité : DTU
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1499786.0 €

Cholesterol transport proteins (CTPs) regulate cellular metabolism, hormone biosynthesis, and organelle contacts, with profound consequences for human health and disease. Despite this, almost no small molecule CTP modulators have been reported, and no methods for determining selectivity across the broader protein class exist. Selective CTP inhibition is conceptually challenging as all CTPs are structurally similar and bind cholesterol. Furthermore, due to redundancy among several CTPs, deciphering the biological roles of their individual cholesterol transport activity has been difficult. ChemBioChol aims to unravel the functions of individual CTPs by developing selective small molecule modulators. Based on seminal work from my lab, I propose employing a sterol-inspired compound design strategy consisting of a primary sterol fragment as “anchor” for CTP binding, fused to secondary natural product fragments to engineer selectivity of the compounds for individual CTPs. My group will develop bio-physical and -chemical tools to determine lipid selectivity of CTPs and optimise selective molecules against them. Preliminary data on the Aster CTP family provides a proof-of-principle that selective and potent chemical tools are attainable, and that the concept is applicable to further CTP families. To determine cellular selectivity of CTP inhibitors against all cholesterol-binding proteins, I will also develop a mass spectrometry-based chemical proteomic approach with a universal cholesterol probe. Optimised CTP inhibitors will be used to determine how CTPs mediate lipid metabolism and trafficking, and their effect on sterol-mediated processes including mTOR signaling and autophagy, with potential applications in neurodegenerative disorders and cancer. A general approach for selectively modulating CTPs is ground-breaking and will have impact beyond this set of proteins by providing a blueprint for studying and targeting other families of lipid-binding proteins in the future.

Mots-clés : cholesterol transport proteins,lipids,natural products,tool compounds
Projet ERC : DEMO-LIES (Horizon Europe, appel 2024, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Institutions, Governance and Legal Systems
Entité participante : Université d'Anvers — Pays : Belgique — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1500000.0 €

In today’s age of ‘misinformation’, politicians are frequently accused of bending the truth to their advantage. As citizens rely on accurate and accessible information to meaningfully engage with politics, political lying violates the contract between citizens and their elected representatives. Political lying accusations therefore have the potential to erode citizens’ trust in and commitment to representative democracy as a system of governance.  While political lying accusations may be as old as politics itself, we know little about when accusations of political lying take root, how accusations of political deception are perceived by citizens, and what their effects are on citizens’ democratic citizenship. To shed light on the issue of political lying accusations and its implications for democratic citizenship this project: (1) describes the historical trends in political lying accusations; (2) identifies the conditions under which politicians accused one another of deception, and characterizes the attributes of both the accused and accusers of political lying; (3) studies citizens’ perceptions of accusations of political deception by exploring the individual and contextual factors that influence these perceptions; (4) investigates the consequences for democratic citizenship by examining how exposure to lying accusations affects citizens’ trust in democracy, their support for liberal democracy as a system of governance, as well as their active engagement with politics. The empirical analyses focus on 20 European countries and rely on an integrated multi-method approach including automated text analysis, qualitative interviews, observational and experimental surveys, and longitudinal survey evidence.  By addressing these critical knowledge gaps, this project will provide invaluable insights into the dynamics of political deception and its consequences for democratic citizenship.

Mots-clés : political lying accusations deception democratic citizenship
Projet ERC : TuneTMD (Horizon Europe, appel 2022, Starting grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Systems and Communication Engineering
Entité participante : Université technique du Danemark — Pays : Danemark — Rôle : PI
Acronyme de l'entité : DTU
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1499578.0 €

In optical quantum computing, qubits are encoded on single indistinguishable photons emitted by single-photon sources (SPSs). The computation is carried out by interfering single photons and by measuring the output using single-photon detectors. A scalable optical quantum computer requires many individual SPSs emitting indistinguishable single photons, however, different SPSs emit light at slightly different wavelengths due to fabrication imperfections. This issue can be resolved by implementing an active control for each SPS to ensure generation of completely identical photons. Despite recent progress, active control of individual SPSs still remains one of the biggest challenges in future quantum technologies. Moreover, the vision of constructing an on-chip platform by integrating SPSs, waveguides, and detectors into a single planar chip is challenging due to the complicated integration of the conventional material platforms. The TuneTMD project aims at developing a tunable on-chip integrated optical circuit using fully nanoengineered mono- and multilayer transition metal dichalcogenides (TMDs), and performing Hong-Ou-Mandel experiments on-chip. I hypothesize that unique optical and physical properties of multilayer TMDs such as high refractive index, low loss at telecom range, active tuning capability, and easy integration between different types of TMDs, combined with optimized nanopatterning techniques make nanoengineered TMDs the ideal semiconductor platform to build tunable, on-chip, fully integrated quantum optical circuits. I will exploit my expertise in nanophotonics and 2D materials to fabricate novel TMD photonic devices, e.g. SPS, waveguide, beamsplitter, and detector. Then I will integrate them on a chip to construct fully integrated quantum optical circuits. Finally, to demonstrate the ground-breaking nature of the proposed platform, I will perform a Hong-Ou-Mandel experiment with two tunable sources.

Mots-clés : single photon source,two dimensional materials,tmd nanophotonics,quantum optics,on chip quantum photonic circuits
Projet ERC : TANGO2 (Horizon Europe, appel 2022, Starting grants)
Domaine scientifique : Life Science
Panel : Environmental B iology, Ecology  and E volution
Entité participante : Université de Lund — Pays : Suède — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1657193.0 €

Living without oxygen is challenging. To live in low-oxygen environments, some microbes exchange nutrients allowing for a division of labor among individuals in a process called ‘syntrophy’. Such interactions are often a pre-requisite for prokaryotes living in these environments. Whether syntrophy is necessary for the survival of microbial eukaryotes (protists) is unexplored and yet, critically important to discerning the roles of eukaryotes in nature and how eukaryotic cells adapt to live without oxygen.  TAngO2 will test the hypothesis that syntrophic partnerships allow eukaryotes to thrive in anaerobic environments and underpin the evolution of key eukaryotic cell biological characteristics. This will be accomplished using state-of-the-art genomic, computational, and experimental approaches.  I will discover genes essential for interactions between a model protist and its ectosymbiont using massively-parallelized transposon mutagenesis. This will discern the molecular mechanisms, metabolic interplay, and selective forces dictating eukaryote:prokaryote interactions.  I will deliver metagenomes of cultured anaerobic eukaryote:prokaryote consortia predicted to be engaging in syntrophic interactions. This will drastically expand our knowledge of the biodiversity of eukaryotic genomes and microbial interactions from low-oxygen environments. I will interrogate the frequency and diversity of syntrophy in eukaryotes by simultaneously sequencing the genomes and transcriptomes ofindividual protist cells and their microbiota sampled from nature. This will provide the first elucidation of what communities co-exist with natural anaerobic protists.  Understanding how syntrophic interactions have influenced eukaryotic cell biology will reveal hidden connections in the complicated functional networks of the eukaryotic cell. TAngO2 will open research avenues by bridging the fields of evolutionary cell biology and microbiology to understand ancient and recent symbiotic

Mots-clés : mitochondrial evolution,protists,anaerobic metabolism,syntrophy
Projet ERC : SHORE (Horizon Europe, appel 2024, Starting grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Products and Processes Engineering
Entité participante : Université technique du Danemark — Pays : Danemark — Rôle : PI
Acronyme de l'entité : DTU
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1497100.0 €

Beaches are eroding at many locations around the world and, with the pending climate change (sea level rise and increased storminess in Northern Europe), coastal erosion is expected to potentially worsen. State-of-the-art practical engineering models for predicting sand and particle transport struggle with the cross-shore processes (perpendicular to the beach), and they even have difficulties predicting the sign right (offshore transport vs. onshore transport), in an experimental setting where the boundary conditions are fully known. The shortage of state-of-the-art models also means that the spreading of microplastic particles, which are increasingly polluting the oceans cannot be predicted accurately. As a result, the future shape of the world’s coastal profiles and the fate of microplastic particles in the coastal region are largely unknown. SHORE aims to bridge this knowledge and competence gap and develop the first model capable of accurately simulating both on and offshore transport of sediments and microplastic particles without case-specific calibration. The new model will (1) break from central assumptions used in existing state-of-the-art models, (2) utilize integrated rather than local quantities and (3) include additional factors known to govern the physics in the complex region around the shoreline. The development of the novel model will be made possible by gathering a novel experimental database containing measurements across a wide range of scenarios and utilizing more advanced numerical models. These advanced models are too computationally heavy to be used to study morphology, but due to recent breakthroughs by my colleagues and I they can be used to study the governing processes. The model developed within SHORE will subsequently be used to answer questions of great interest to research and society, such as the effect of climate change on coastal profiles and microplastic hotspots.

Mots-clés : sediment transport waves coastal profiles cross shore processes numerical modeling
Projet ERC : GENESIS (Horizon Europe, appel 2023, Starting grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Institutions, Governance and Legal Systems
Entité participante : Université d'Anvers — Pays : Belgique — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1488784.0 €

The 2030 Agenda for Sustainable Development and the Sustainable Development Goals hail multistakeholder partnerships (MSPs) as key actors in achieving sustainable development. MSPs that bring together states, businesses, philanthropy and civil society are increasingly in the frontlines of providing public goods that are human rights such as food, health, education and water. In these domains, partnerships are spearheading the continued expansion of multistakeholder governance into international law, including human rights law. This expansion has been taking place without critical appraisal with respect to its effectiveness and consequences.GENESIS breaks new ground by exploring the normative and operational implications of this shift, both at the system-level and at the level of specific global partnering initiatives and individual multistakeholder partnerships. GENESIS investigates the interface of international law and multistakeholder governance in the realisation of human rights. It analyses how the paradigms of multilateralism and multistakeholderism diverge or converge as they simultaneously govern the domains of food, health, education and water through human rights law and multistakeholder partnerships, respectively.  GENESIS has three main objectives that will generate high research and policy gains. First, GENESIS will uncover and understand how norms that govern human rights through multistakeholder partnerships are made in the post-2015 era in the governance of food(SDG 2), health (SDG 3), education (SDG 4) and water (SDG 6). Second, GENESIS will investigate how multistakeholder partnerships impact the way human rights are operationalised. Third, GENESIS will identify pathways to an effective uptake of human rights legal standards by multistakeholder partnerships. In doing so, GENESIS will derive insights on whether and how international law and multistakeholder governance can generate common ground when governing public goods that are human rights.

Mots-clés : human rights,multistakeholder partnerships,multistakeholderism,multilateralism,governance,public goods