Data-Gouv-ML/pcri-erc-participations-et-projets-laureats huggingface dataset:
Projet ERC : ABIDE (Horizon Europe, appel 2021, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Soci al World and Its Interactions
Entité participante : Université de Lisbonne — Pays : Portugal — Rôle : PI
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1999970.0 €

What and how can we learn from animals about recovering from disasters? How can we hear them in their own terms, translate their stories, and include their perspectives, in human knowledge about disasters? This project explores the resilience of multispecies communities, and their capacities for healing and bouncing back from disasters, through the point of view of nonhuman animals. It departs from the current context of acute climate crisis, which sets the stage for Dantesque scenarios of impending climate-driven disasters such as wildfires, floods, tornados and hurricanes, with related extensive loss of both human and nonhuman lives, liveable dwellings and species extinction. Focusing on wildfires as disasters that challenge previous expert knowledge due to climate change and human exploitation of natural resources, we propose to compare three countries where wildfires have taken on increasingly critical proportions every year: Brazil, Australia and Portugal. We address a species gap in our knowledge of disasters, and wildfires in particular, by exploring the possibilities of learning with animals how to live and cope with extreme change and uncertainty in wildfire-prone areas. Drawing on contributions from sociologists, anthropologists, ethologists, biologists and geographers, ABIDE aims at attuning to, translating and including the voices, stories and experiences of animals into our knowledge of how multispecies communities can better recover from the traumatic experience of wildfires. In the end, we seek to build the foundations for a new interdisciplinary framework for addressing humans' and animals' ability to build and abide in multispecies communities that are more resilient to wildfires and other disasters. In so doing, we aspire to identify the landmarks of a post-species episteme, and thus push forward the frontiers of knowledge of human-animal relations, as well as contribute to a more-than-human governance of disasters.

Mots-clés : human animal relations,multispecies relations,nonhuman animals,multispecies ethnography,multispecies methodologies,disasters,wildfires,climate change,global environmental crisis,biodiversity,disaster trauma,disaster resilience,disaster recovery,disaster governance
Projet ERC : ZIGNALLING (Horizon Europe, appel 2023, Consolidator grants)
Domaine scientifique : Life Science
Panel : Cell Biology, Development, Stem Cells and R egeneration
Entité participante : Université de Gand — Pays : Belgique — Rôle : PI
Acronyme de l'entité : UGent
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1983531.0 €

Nucleic acids are potent activators of an immune response. Z-nucleic acids are poorly defined and thermodynamically unstable conformers of double-stranded RNA/DNA helices. Recently, others and our group showed that Z-nucleic acids are recognised by the nucleic acid sensor ZBP1, thereby inducing an antiviral immune response. Activation of ZBP1 has also been shown to induce anticancer immunity and it is becoming clear that chronic engagement of ZBP1 by endogenous Z-nucleic acids causes autoinflammatory pathology. On top of that, a remarkably diverse set of cellular insults, ranging from pathogens and chemicals to genetic mutations trigger ZBP1 activation. Despite its relevance in these important (patho)physiological events, knowledge on the fundamental principles that govern Z-nucleic acid-induced ZBP1 signalling is lacking. I here propose that ZBP1 perceives these widely different disturbances in cellular physiology by detecting the increased intracellular concentrations of Z-nucleic acids. Based on a newly developed ZBP1 activation model and using nanopore sequencing, structural biology and chemical or genetic perturbation methods, we will: (i) characterise the molecular mechanisms that regulate Z-nucleic acid levels, (ii) determine the biophysical determinants of ZBP1 activation, (iii) map the ZBP1 downstream signalling network and (iv) functionally validate our novel findings in cellular and in vivo models of ZBP1 activation.  The resulting detailed mechanistic understanding of ZBP1 function from single molecule to organism will enable us to develop future strategies for therapeutic interference with ZBP1-mediated immune responses, either negatively, to resolve autoinflammation, or positively, to promote antiviral or anticancer immunity.

Mots-clés : nucleic acid immunity,zbp1,z dna,z rna,nf kappab,apoptosis,necroptosis,ripk1,ripk3
Projet ERC : GROUNDOC (Horizon Europe, appel 2024, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Institutions, Governance and Legal Systems
Entité participante : Université de Gand — Pays : Belgique — Rôle : PI
Acronyme de l'entité : UGent
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1999750.0 €

Transitional justice (TJ) is the field of scholarship and practice that examines how societies deal with the consequences of massive human rights violations. A decade of critical TJ scholarship may create an impression of a field in crisis. Yet, TJ practice seems to be thriving: TJ language and initiatives are travelling to increasingly diverse contexts, which are often very different from those in which TJ emerged. Examples are TJ initiatives to address ongoing conflict or historical injustice. The manifestations of TJ in these ‘aparadigmatic’ cases are often so distinct that they challenge the foundation of the TJ paradigm. Notably the innovations, ambitions, and experimentation happening in these cases invite for a rethinking of TJ's standard mechanisms and objectives, which currently revolve around the pillars of justice, truth, reparation, non-recurrence and memorialisation. This project goes beyond definitional debates over whether these processes are ‘real’ instances of TJ. Instead, I argue that properly theorizing the innovations happening in these aparadigmatic cases is crucial to close the emerging gap between theory and practice, and that it can even be a way to address some of the most pressing critiques of paradigmatic TJ. I will use a mixed-method actor-oriented approach to analyse the practices and ambitions of grassroots justice actors in 6 aparadigmatic cases. This analysis will foreground documentation initiatives because there is significant innovation happening in this realm, and because documentation’s central role across all TJ initiatives means that this innovation has the potential to amend the entire paradigm. I will adopt an eco-systemic analytical framework to examine how (innovations in) documentary practices interact with and affect other (transitional) justice initiatives. I then build on this empirical analysis to reconstruct the TJ paradigm from the ground up. The envisioned outcome is a practice-informed & future-oriented TJ paradigm

Mots-clés : transitional justice,transformative justice,historical injustices,accountability,mixed method approach
Projet ERC : SovereignPerformance (Horizon Europe, appel 2024, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Institutions, Governance and Legal Systems
Entité participante : Université de Gand — Pays : Belgique — Rôle : PI
Acronyme de l'entité : UGent
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1997994.0 €

Existing analytical approaches are poorly equipped to make sense of political entities that aspire sovereign statehood and present themselves accordingly, but which lack a recognised status. The prevalent scholarship struggles to categorize sovereignty-aspiring entities.  This project departs from the extant literature in that it places the unsettled nature of sovereignty-aspiring entities – their defiance of categories – at the heart of the equation. Rather than resolving the interpretative “to be of not to be” dilemmas around their status and activities, the inherent contingency of separatist politics becomes our central vantage point. Turning to political performativity and aesthetics, the project seeks to determine how the performative repertoires of sovereignty-aspiring entities create democratic political space to bend or break the bounds of the formal institutional landscape.  The project centres on three case contexts, which are highly rich and highly diverse: the Catalonian independence movement, the autonomous administration of Rojava (Syria) and the Tamil nationalist movement in Sri Lanka. It takes an inductive approach to then corroborate our findings within and beyond these cases. The project is structured around four inter-connected work packages each with its own research question and method. 1) We will use political ethnography to establish what political repertoires sovereignty-aspiring entities use. 2) We will use qualitative content analysis and art-based methods to assess the aesthetic dimensions of these repertoires. 3) We will use focus-group workshops to establish constituencies' understandings of these repertoires. 4) We will build a database of separatist political repertoires around the globe to validate our findings.  The project’s overall objective is to give a new impetus to the study of separatist conflicts with a rich and robust research agenda that combines a new conceptual lens with an innovative methodological approach.

Mots-clés : contested sovereignty performative politics political ethnography separatist conflict political violence and civil war catalonian independence movement rojava autonomous administration sri lankan tamil nationalism
Projet ERC : KNOW (Horizon Europe, appel 2021, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Study of the Human Past
Entité participante : Université de Gand — Pays : Belgique — Rôle : PI
Acronyme de l'entité : UGent
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1996396.0 €

KNOW is the first comprehensive study of polymathy and interdisciplinarity in premodern Islam. The project sets out to write a history of knowledge that takes the interaction between disciplines as its primary subject. The project’s historical framework is the post-formative period, 1200-1800 CE, which saw the rise of new institutions of learning, the proliferation of libraries, the formation and integration of disciplines and curricular texts, and an increase in academic travel, facilitating interdisciplinary cooperation, competition and conflict. Despite its significance, our knowledge of this period remains rudimentary. The project promises to transform our understanding of the intellectual dynamics of this period by applying the lens of polymathy and interdisciplinarity. Previous scholarship has focused on intellectual products (i.e., doctrines and texts) and has tended to project our contemporary disciplinary divisions onto the premodern period (e.g., humanities v. sciences; religious v. secular). This project departs from these approaches by focusing on epistemic processes and practices rather than products and artefacts. To do so, the project tests three research hypotheses: (1) cultural and intellectual vibrancy of the premodern period is evident in the interaction between disciplines, (2) madrasa education and hospital culture produced an interdisciplinary space, (3) interdisciplinary practices created a common scholarly language. The project’s interdisciplinary methodology draws on the history of science, interdisciplinary studies and polymathy studies. The PI will be supported by an interdisciplinary team of three postdoctoral researchers covering, together, the intersections between philology, theology, exegesis, law, medicine, logic, algebra, and geometry in premodern Islamic epistemic cultures. Know will make significant contributions to interdisciplinarity and polymathy studies, as well as the emergent field of the history of knowledge.

Mots-clés : islamic intellectual history,arabic,qur an,interdisciplinarity,islamic theology,islamic law,islamic science
Projet ERC : DAEDALOS (Horizon Europe, appel 2021, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Study of the Human Past
Entité participante : Université de Gand — Pays : Belgique — Rôle : PI
Acronyme de l'entité : UGent
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1876640.0 €

DAEDALOS aims to challenge the predominant metanarrative that uniformly sees monuments as an attribute of centralised, hierarchical political economies and top-down power structures, a view that exerts a strong influence on our understanding of the organisation of Bronze Age Eastern Mediterranean societies. In the 2nd mill. BCE, Mainland Greece, Western Anatolia and the islands of Crete, Cyprus and the Cyclades witness a growing architectural elaboration. Impressive ‘palatial’ monuments are built, which are often interpreted as the seat of rulers exerting centralised control over the population. The surmised political power necessary for the mobilisation and management of the human and material resources invested in monumental construction is taken as further evidence for the leading function of these edifices, and for the position of their commissioners at the top of hierarchical socio-political systems. Taking into consideration the ability for human groups with no centralised leadership to efficiently manage and control resources, DAEDALOS questions the preconceived conflation of monumental architecture and centralised hierarchical power. To assess this, the project will analyse integration and segmentation patterns in 2nd mill. BCE monumental building projects of the Aegean and Cyprus, and investigate the organisational centralisation of the societies that managed the labour and material resources invested in construction. Based on the architectural study of monuments distributed over 35 sites and their examination through new, specially devised analytical parameters, DAEDALOS will explore the possibility for grassroots, bottom-up building processes and their impact on architectural creation. By doing so, the project aims to trigger a paradigm shift in the ways we approach and interpret monumental architecture while producing nuanced and compelling definitions of Eastern Mediterranean Bronze Age socio-political systems.

Mots-clés : monumental architecture monumental building projects building process ancient architecture palaces resources mobilisation resources management collective performance collective action construction sequence cooperation dynamics scale of monuments architectural energetics craftspeople architectural labour gis web gis spatial analysis ancient leadership socio political organisation bronze age societies dual processualism
Projet ERC : LearnInCycle (Horizon Europe, appel 2022, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : Individuals, Markets and Organisations
Entité participante : École des hautes études commerciales de Paris — Pays : France — Rôle : PI
Acronyme de l'entité : HEC Paris
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 1147981.0 €

The Eurozone is currently facing a sudden and sharp increase in inflation. Whether inflationary pressures will persist and what will be the cost of an eventual monetary tightening crucially depends on inflation expectations. The aim of this project is to provide theoretical and empirical support to a new channel, through which inflation may persistently shift business activity. The project sheds new light on how market prices influence consumers’ perceived inflation and how this may allow for the transmission of monetary policy even in the absence of rigidities in firms’ pricing. It shifts the focus from a traditional firm-centric to a (complementary) household-centric view of money non-neutrality. It shares the spirit of a recent trend in central banks’ efforts in getting a better appraisal of the importance of consumers’ expectations, after decades of a strict empirical focus on firms’ pricing. The project consists of five working packages (WP) based on the idea that households’ inflation perceptions, driven by actual market prices, can be a major source of the business cycle. The first WP proposes a new theory where output-inflation co-movement relies on consumers’ price hunting in response to perceived inflation, causing a counter-cyclical gap between posted and paid prices inflation. The second and third WP aim at validating the mechanism using large datasets on consumers’ spending and retail trade. The fourth presents a new model where consumers learn from inflation about future economic prospects on which all have dispersed foresight. The fifth will estimate this model on survey data. The key novelty of the project is studying, not only how expectations move market outcomes, as typical in the literature, but also how these feed-back to expectations through prices in a full circle of general equilibrium implications. As by-product, it identifies measurable empirical counterparts for incomplete information sets.

Mots-clés : inflation information frictions market prices,inflation expectations,business fluctuations,search,learning,information and knowledge,communication,belief,unawarness monetary policy central banks and their policies market structure,firm strategy,and market performance
Projet ERC : SOS (Horizon Europe, appel 2022, Consolidator grants)
Domaine scientifique : Social Sciences and Humanities
Panel : The Study of the Human Past
Entité participante : University College Dublin — Pays : Irlande — Rôle : PI
Acronyme de l'entité : UCD
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 2000000.0 €

In 2015, over one million boat refugees sailed across the Mediterranean. This was not the first time that people took to the seas in search of asylum. During the 1940s, Jewish boat refugees voyaged across the Mediterranean; in the 1970s and 1980s, Vietnamese boat people traversed the South China Sea; in the 198In 2015, over one million boat refugees sailed across the Mediterranean. This was not the first time that people took to the seas in search of asylum. During the 1940s, Jewish boat refugees voyaged across the Mediterranean; in the 1970s and 1980s, Vietnamese boat people traversed the South China Sea; in the 1980s and 1990s, Cubans and Haitians tried to navigate the Caribbean to reach the US; and in the 1990s and 2000s, boat refugees sailed across the Indian Ocean, the Gulf of Aden and the Mediterranean in an attempt to reach Australia, Yemen, and Europe respectively. The central research question framing this project is: how did notions of solidarity, sovereignty and sanctuary influence the experience and reception of boat refugees across time and space? The research team will be guided by the related sub-question: who hindered and who helped boat refugees on their journeys, and why?   Each of the sub-projects will examine a) whether there was solidarity onboard between boat refugees, b) whether boat refugees encountered solidarity from non-state actors, such as merchant vessels, fishing boats and NGO search and rescue missions, c) how states responded to boat refugees at sea, and d) whether boat refugees attained sanctuary after their journey.  This project’s ground-breaking character lies in three aspects: 1) thinking through seas, 2) going beyond the state, and 3) comparing the experience and reception of boat refugees across time and space. The main sources that the project will rely upon will be interviews with boat refugees, non-state and state actors, oral history, state archives, NGO archival collections, legal cases, and contemporary media coverage.

Mots-clés : boat refugees refugee policies refugee journeys migration history
Projet ERC : ReZone (Horizon Europe, appel 2023, Consolidator grants)
Domaine scientifique : Physical Sciences and Engineering
Panel : Products and Processes Engineering
Entité participante : University College Dublin — Pays : Irlande — Rôle : PI
Acronyme de l'entité : UCD
Type d'entité : Enseignement supérieur ou secondaire
Financement ERC de l'entité : 2265746.0 €

Articular cartilage (AC) has a complex zonal structure and composition, providing it with its essential functional properties. However, when cartilage is damaged, the zonal complexity does not regenerate, leaving an inferior tissue which is prone to degeneration. As a result, cartilage injury commonly leads to pain and the eventual need for joint replacement. Progress towards true regeneration of AC requires an advance in understanding of how zonal complexity (and corresponding function) emerge over development. The most promising clue to understanding zonal emergence is that mechanical forces are known to be important for normal AC development.  ReZone will reveal the mechanisms underlying zonal emergence through a novel goat model in which a common veterinary procedure is repurposed to create a radically altered mechanical environment in the developing joint. By comparing gene activity between normal and altered states of zonal emergence, I will identify pathways likely to be involved in zonal emergence. I will leverage my expertise in cartilage explant culture and mechanostimulation bioreactors to develop a novel in vitro explant model, and use this model to validate candidate pathways. Finally, I will demonstrate the therapeutic potential of molecular regulators of zonal emergence using gene-activated biomaterials to regenerate zonal emergence in an in vivo, large-animal model of cartilage repair.  ReZone will provide a step-change in our understanding of how zonal AC develops postnatally, including the role of mechanical loading. The project’s ambitious aim is to bring about enhanced regeneration of AC through activation of the developmental processes which form functional cartilage in early life. Revealing key mechanisms underlying zonal emergence in immature AC will enable true regeneration of injured AC, improving quality of life for patients with articular cartilage defects worldwide.

Mots-clés : articular cartilage development mechanical loading extracellular matrix composition,structure and mechanical properties