Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet DNANanoProbes (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The project is aimed to develop the novel technique of fluorescent signal amplification upon detection of RNA sequences in living cells up to a single copy level. The novel interdisciplinary approach will be focused on design of innovative fluorescent nanosensors based on polymer nanoparticles (NPs) incorporated with organic dyes, functionalized with DNA shell. The project is predicated on the innovative design of DNA-nanosensors, proposed by the Applicant, which is built on groundbreaking findings of the Host laboratory on ultrabright organic NPs and giant light-harvesting phenomenon that enable strong amplification in detection of nucleic acids. The project relies on contemporary spectroscopy/microscopy facilities and developments of the Host group, and the strong experience of the Applicant in synthesis of fluorescent dyes, design of DNA-probes and bioconjugation techniques.

Mots clés : bioimaging, hybridization assay, light harvesting, fret, dna probes, biosensors, polymer nanoparticles

Participants :
- Université de Strasbourg (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 196707.84 €
Projet MODFIN (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : CLOSED

The project is in model theory (mathematical logic), which concerns the expressibility in logical languages of properties of mathematical structures (e.g. graphs, groups, rings). Model theory aims to identify borders between `tame' and `wild' objects in mathematics, and to pin down abstract notions of independence and dimension and understand the geometry of `definable sets' in a structure, often with wide-ranging applications. This project focusses on classes of finite structures (e.g. the class of all finite fields), and on the `ultraproduct' construction which converts a class of finite structures to an infinite `pseudofinite' structure' which inherits properties of the class and is amenable to model-theoretic methods, with applications for the finite structures. Key objectives include: (i) proving a trichotomy for pseudofinite geometries -- they should be `trivial', `group-like', or `field-like'; (ii) developing current concepts from abstract model theory for pseudofinite structures; (iii) identifying first order properties of pseudofinite groups, and constraints on their possible quotients; (iv) finding links between the model-theoretic `independence theorem', Gowers' notion of `quasi-random groups', and the Szemeredi regularity theorem in graph theory. (v) model theory of finite ordered structures, and links to finite model theory. To support his future academic research career, the Fellow, Garcia, will receive training through research in the model theory groups in Leeds and (through a secondment) Lyon. There will be knowledge transfer to Garcia of expertise in model-theoretic algebra of Leeds and Lyon, and Garcia will also build knowledge of finite model theory and its computer science applications. He will receive complementary training in many research skills (including outreach), and will transfer to Leeds expertise he has gained in the excellent model theory groups in Berkeley and Bogota, while deepening EU-Colombia mathematics links.

Mots clés : model theory, pseudofinite, group, combinatorics, finite model theory, o minimal, finite field, stable theory

Participants :
- University of Leeds (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet PeSD-NeSL (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The project of “PeSD-NeSL” is a fundamental and scientific project that will be carried out by Dr. Jin Zhang under the supervision of Prof. Angel Rubio. Dr. Zhang is a theoretical scientist with extensive experience and good publication records in the field of laser-excited carrier and structural dynamics. Prof. Rubio is the managing director of the Theory Department of MPSD and one of the leading experts in fields of ab initio calculations of electron excitations and dynamics in Physics, Chemistry, and Biophysics. This project will also involve collaborations with top international experimental and theoretical groups. The proposed project “PeSD-NeSL” is focusing on the non-equilibrium states and dynamics under laser in van der Waals (vdW) stacked materials, including carrier multiplications, light-induced Moiré engineering, interlayer Moiré exciton, light-induced insulator-metal phase transition among others. The intriguing processes provide a strong motivation for studying microscopic details of optical responses in vdW materials upon laser excitation. The underneath microscopic interactions among photon, electron, exciton, phonon and other quasi-particles are crucial and far from being clearly understood as they relate to the macroscopic quantum phenomena. We will perform state-of-the-art numerical experiments in three parts: Part 1. Carrier multiplications in two-dimensional monolayers and vdW heterostructures; Part 2. Light-induced Moiré engineering and Moiré excitons in vdW bilayers; Part 3. Photoinduced phase dynamics and non-equilibrium states in TMD layers. We aim to establish a clear relationship between microscopic interactions and macroscopic quantum phenomena in low-dimensional materials under field perturbations. The success of “PeSD-NeSL” will consolidate the leadership of MPSD group in condensed matter physics, material science, and nanoscience, and create more advanced and effective methodological tools for other scientists in related fields.

Mots clés : excited state dynamics, non equilibrium states, van der waals materials, first principles calculations, tddft, many body perturbation theory

Participants :
- Max Planck Society (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 174806.4 €
Projet COOLandHOT (Horizon 2020, appel à projets 2016)
Action : European Researchers' Night
Statut du projet : CLOSED

The project proposal under the title Cool & Hot (COlest Of Labs & Hottest Of Theories) mixes, blends and unites faces, voices, results and energies of many generations of researchers in offering the public at large, regardless of their age and scientific background, the opportunity to get up-close and personal with researchers. However, a special emphasis in this project will be given to inspiring and motivating next generations of scientists. Since young adults are all about what is hot and what is cool, we have chosen to focus on those specific aspects of science and researchers. The outlined concept and the content planned will help achieving the following specific objectives: • To break and demystify the persistent and repeated stereotypes about researchers; • To bring out the actual researchers in Serbia, engage them publically and increase their recognition in Serbian society – locally, but globally as well; • To promote research carried out in Serbia and researchers as role models; • To unveil the motives behind becoming a researcher; • To entice the young to embark on scientific careers; • To raise public awareness of the researchers' contribution to progress and development; • To raise public awareness about climate changes and global warming; • To highlight the importance of the EU’s manifold support to researchers and scientific research work in Serbia; • To improve networking with other national/international projects involved in science popularization, through mutual support of events and exchange of ideas, experiences and people.

Mots clés : cool, attractive, futuristic, understanding, connecting, helping, researchers, science, innovative

Participants :
- Kreativno Edukativni Centar (Serbie) — Partner, beneficiary, Autres, subvention : 40000.0 €
- University of Novi Sad (Serbie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 14000.0 €
- Udruzenje naucnih komunikatora (Serbie) — Partner, beneficiary, Autres, subvention : 14000.0 €
- University of Novi Sad (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 6000.0 €
- Centar za Promociju Nauke (Serbie) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 23000.0 €
- Visoka tehnicka skola strukovnih studija u zrenjaninu (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 12000.0 €
Projet Reconnect Restart 3 (Horizon 2020, appel à projets 2020)
Action : European Researchers' Night
Statut du projet : CLOSED

The project proposal under the title ReConNeCt Restart 3 (REsearch, CONnections, NEtworks and CulTure - Use of Projects, Games, Research And Digital in Education) extends on the previous experience gained in the ReConNeCt project that ran in 2019 and 2020, and after having major changes caused by global pandemic, the main idea of bringing together researchers and the public at large of all ages, will be done in mixed environment live experience with researchers and digital (Virtual and Augmented Reality) enhanced events. As the brink of a new decade always signifies changes and modernization, and since the digital science industry in Serbia is currently blooming, we want to a make the digital science the main theme of the EU Researchers Night in 2021. Placing the digital in focus of our program reflects the trends and interests of the new generations that will create and sustain the future (Gen Y and the coming Gen Z). Naturally, the digital and the virtual overcome the physical and spatial barriers and hence magnify the impact on the young audience whose lives and interactions are nowadays dominantly conducted on a digital plane.

Mots clés : european green deal, digital, innovative, green, sustainable, engaging, entrepreneurial, ground breaking, excellent, collaborative, impactful, enabling, outreach, stakeholders  engagement

Participants :
- Udruzenje naucnih komunikatora (Serbie) — Partner, beneficiary, Autres, subvention : 8000.0 €
- Kreativno Edukativni Centar (Serbie) — Coordinator, beneficiary, Autres, subvention : 41500.0 €
- University of Novi Sad (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 10000.0 €
- Visoka tehnicka skola strukovnih studija subotica (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 7500.0 €
- Centar za Promociju Nauke (Serbie) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 12000.0 €
Projet LiTechAe (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The project proposes for the first time a global approach for the study of stone tools used in masonry in the Bronze Age Aegean. The study focusses on percussive tools used for cutting and dressing stone in Crete, the Cyclades and mainland Greece in the 2nd millennium B.C. This era saw the rise of the first monumental stone architecture in Europe, first in the palaces of Minoan Crete and from the 15th c. BC onwards, in the tombs and citadels of the Mycenaean mainland following trends known since the 3rd millennium BC in Egypt and the Near East . Scholars agree on the use of stone tools along with metal tools in stone masonry. However, in contrast with other contexts (Egypt, Hittite Anatolia), stone tools in question are absent from the archaeological record, and relatively little is known about tools and techniques. Considering that monumental masonry practices require important energy investment and skilled workforce reflecting a complex social organization , understanding related lithic technology is central to an appreciation of how these societies operated . Recent studies also demonstrate that masonry tools and techniques were part of large-scale technological transfers between the Aegean world and the Near East, especially Hittite Anatolia and Egypt . This project will investigate to what degree, in which ways and contexts and why percussive stone tools were used following a multidisciplinary approach: 1) characterization of materials used for tools and masonry, 2) large-scale experimentations testing different types of stone and metal tools on different building materials, 3) multi-scale analysis of use wear traces on both tools and architectural components (archaeological and experimental), 4) comparative ethnoarchaeological study of material issued from key-sites in the Aegean and Anatolia. The research will provide concrete answers to questions of technological order and an important contribution to social agency, cross-craft/cultural interaction issues.

Mots clés : experimental archaeology, use wear traces analysis, stone and metal tools, lithic technology, monumental masonry, crafts, networks, materials, bronze age, aegean, anatolia, eastern mediterranean

Participants :
- Leiden University (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 281358.72 €
Projet B2DTauNu (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The project will characterise the physics of semileptonic b -> c tau nu quark transitions, by studying the angular properties of B -> D(*) tau nu meson decays. The branching fractions of B -> D(*) tau nu decays are measured to be larger than expected relative to their B -> D(*) mu nu counterparts, offering an intriguing hint of beyond the Standard Model (SM) physics in the form of lepton universality violation. Due to the spin structure of B -> D(*) tau nu decays, the full decay rate is described by a sum of twelve angular terms each with a corresponding coefficient. The values of these coefficients can be altered by New Physics (NP) operators such as charged Higgs bosons, Z' bosons, or leptoquarks, and measuring their values thus provides a powerful probe to search for deviations from the SM. The project will use LHCb Run 1 and 2 data to measure the B -> D(*) tau nu angular coefficients and signal yields in a model-independent manner, making use of novel binned template fit methods that fully account for resolution effects caused by the missing neutrino information. The measurements made will be a ground-breaking proof-of-principal, paving the way for high-precision angular coefficient measurements in future.

Mots clés : angular analysis, flavour, leptoquark, r d, hadronic, model independent, new physics, standard model

Participants :
- Board of the Swiss Federal Institutes of Technology (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 203149.44 €
Projet HTS-STABTHERAPRO (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The project will establish a novel high-throughput directed evolution platform for evaluating large libraries of therapeutic protein (TP) variants for increased thermostability, slower global or local unfolding rates, and minimised aggregation propensity. This will require several recent advances to be coupled into a single system. Directed evolution can be carried out by encapsulating single plasmids, each encoding a unique protein variant, into droplets of an emulsion, then using cell-free expression to generate the protein in each droplet. This project will extend this approach to incorporate non-natural amino-acid fluorophores into the protein to create a FRET-based signal that would give a direct report on protein expression levels, and then also on the stability (denaturation) of the protein (FRET-loss) upon stimulation by heating. Such heating will initially be applied to droplets in bulk for defined periods of time to allow global unfolding and aggregation, and then recooled prior to FACS sorting for variants that best retain the FRET signal. Aggregation under native (low temperature) conditions is known to be linked to local protein unfolding events that are relatively rare. To extend the screening approach for directly evolving slower local unfolding events, a fast IR-induced temperature-jump perturbation will be used to cause only local unfolding prior to FACS sorting. Such a platform would be used to directly evolve TPs with increased thermostability (slow global unfolding), and then slower local unfolding, which will combine to decrease aggregation propensity. An enzymatic system (bovine enterokinase) will be used initially to establish and validate the set-up, taking advantage of the simple fluorescent assay for enzyme activity. Once established, the set-up will then be applied to therapeutic antibody fragment proteins, using FRET to screen for retention of folded structure upon heating.

Mots clés : directed evolution, therapeutic proteins, fret, high throughput screening, microfluidics, thermostable protein, antibody fragments

Participants :
- University of London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet EUCHILD (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The project will investigate the effects of EU policies on the deinstitutionalization of child care in non-EU countries of Eastern Europe. These countries have large numbers of children in orphanages and, in recent years, have been moving towards family-based child care policies. The study will be conducted in two parts. Firstly, a unique dataset on national deinstitutionalization reforms and relevant EU interventions in Armenia, Azerbaijan, Georgia, Belarus, Moldova, Ukraine, and Russia will be gathered. After conducting a correlation analysis on these data two countries will be chosen by the positive deviance method, that is, by finding particularly successful countries. These will be further studied using in-depth interviews of NGOs, government officials and international agencies in order to understand how progress has been achieved and what combinations of factors were key to the success of the reforms. This analysis will lead to an in-depth understanding of the drivers of deinstitutionalization in these countries, and will help inform EU policies towards the region. The research will be carried out in the Tampere Research Group for Cultural and Political Sociology at the University of Tampere, led by Prof Pertti Alasuutari, which specializes in the influence of global policy changes on local policy making, and is therefore an ideal base for this project. The applicant, Olga Ulybina, has wide experience in the field of international development, having gained a PhD at the University of Cambridge studying the impact of international movements on Russian forestry reform and received a prize postdoctoral fellowship from WZB Berlin to study international aid interventions in Kyrgyzstan. This background along with the training and support from the research group at the University of Tampere make her ideally placed to conduct this research.

Mots clés : child care, deinstitutionalization

Participants :
- Tampere University (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191325.6 €
Projet MINERVA (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The project ‘MinErVa: Mid-Pleistocene Environments of the lower Vaal River’ seeks a multidisciplinary perspective on the effects of environmental change on human evolution by examining the palaeoenvironmental context of the first anatomically modern humans in the arid interior of southern Africa (c. 300-100ka). The MinErVa project is focused around the archaeological site of Pniel, an Early Middle Stone Age open-air site on the Vaal River that I have been excavating for two seasons since 2017. The site is located in an area with fossil evidence for early human evolution, however, there is a lack of terrestrial proxy records to reconstruct climate and environment during this time period. Specifically, the project will test the hypothesis that the local environment included phases of persistent wetness and significant biome shifts, caused by increased winter rainfall, though carbon and oxygen stable isotope analysis on herbivore teeth. Furthermore, MinErVa will apply innovative carbon and hydrogen stable isotope analysis on leaf wax n-alkanes in sediment to reconstruct vegetation and palaeohydrology. In a synthesis with isotopic, zooarchaeological, geomorphological, phytolith and lithic data sets recovered from my ongoing excavations, this project will explore how the first Homo sapiens were adapting to their environment. The project offers scope for testing the application of stable isotope analysis of leaf wax isotopes in sediment for the first time in a terrestrial context of this antiquity on South Africa and will therefore offer unique training to the applicant in a novel method which can has the scope to establish new proxy records in a region where there is a distinct lack of them.

Mots clés : middle stone age, south africa, palaeoenvironments

Participants :
- Kiel University (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 162806.4 €
Projet EcoGemCoat (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The project, EcoGemCoat, involves the preparation of smart anticorrosion coatings based on mesoporous silica nanocontainers loaded with innovative, eco-friendly cationic gemini surfactants as high efficient corrosion inhibitors of carbon steel in seawater with the potential application in marine and offshore industry. The main aim of EcoGemCoat will be achieved by performing four specific goals: 1) preparation of novel corrosion inhibitors (synthesis of the surfactants and structure confirmation) with low toxicity; 2) testing of the inhibitors (aggregation behaviour tests, biological tests, electrochemical corrosion inhibition tests); 3) preparation of smart coatings (immobilization of surfactants, characterization of nanocontainers, release study, smart coating preparation); 4) corrosion, mechanical and biological tests of the developed coatings. The proposed project involves different areas of science as organic chemistry (synthesis of inhibitors), analytical chemistry (aggregation behaviour, release study), electrochemistry (electrochemical corrosion tests), environmental science (toxicity and bioaccumulation tests) and materials science (mechanical tests), which makes topic interdisciplinary in nature. The research of encapsulation of the cationic gemini surfactants will be attempted for the first time, as well as the resulting type of smart anticorrosion coatings. Furthermore, the use of green inhibitors as additives of smart and eco-friendly coatings might change the coating Industry paradigm, answering to some of the EU societal challenges for the present and future decades. Equally relevant is the high quality of training to which the candidate will have access, thus fostering a reinforcement of the candidate’s position in the scientific community as an independent researcher and will ultimately have a significant positive impact on the fellow's future career in corrosion research.

Mots clés : corrosion inhibitors, corrosion protection, coatings, electrochemistry, green chemistry

Participants :
- University of Aveiro (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148635.6 €