Projet LipidBRIGHT (Horizon Europe, appel à projets 2024)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

Recent insights revealed new, decisive roles for lipids in cardiovascular disease, chronic kidney disease, cancer and chronic inflammation. Lipid targeting may offer novel treatment opportunities for these four high-impact diseases, complementary to the currently available, insufficiently effective therapies. However, developing effective diagnostic, preventive and therapeutic solutions requires deeper insights into lipid metabolism in disease as well as improved methods of lipid detection and imaging. Furthermore, an increasing interest in lipids in clinical applications, demonstrated by our associated partners, generates job profiles requiring novel, lipid-focused, interdisciplinary training. LipidBRIGHT is the first lipid-focused ITN designed to address the unmet medical need to i) better understand lipid metabolism in disease and ii) train young scientists in the emerging lipids field, associated technologies and clinical applications, this to speed-up understanding of lipid-associated diseases and translation into novel strategies for disease diagnosis, prevention and treatment.  LipidBRIGHT comprises 6 forefront-running, interdisciplinary and intersectoral research institutes and 2 SMEs with complementary expertise in lipid-associated diseases, technology and translation, supported by 4 academic and 1 international research institute, 3 SMEs, 4 international companies, 2 stakeholder-representing organisations and 1 international organisation of mixed academic/private members. With established cooperations, we will train doctoral students around three pillars: (i) Lipid biomarkers, artificial intelligence and disease modelling, (ii) Lipid-associated pathology & disease mechanisms, and (iii) Lipid application in clinics & industry. This will provide excellent scientific, technological and transferable skills to generate innovative insights in the opportunities of lipid research, and boost EU competitiveness in lipid research, translation and application.

Mots clés : lipids, fatty acids, lipidomics, biomarkers, cellular signaling

Participants :
- Université de Montpellier (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Fresenius Medical Care (Germany) (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Boehringer Ingelheim (Germany) (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Nancyclotep (France) — Partner, associated partner, Recherche, subvention : 0.0 €
- European kidney health alliance (Belgique) — Partner, associated partner, Autres, subvention : 0.0 €
- KU Leuven (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 288540.0 €
- RD Néphrologie (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 314669.16 €
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 314669.16 €
- Leadership sculptor gmbh (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université d'Utrecht (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 305285.76 €
- Université de Maastricht (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 890416.8 €
- Aspect analytics (Belgique) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Corden pharma switzerland llc (Suisse) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University Hospital Aachen (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Mvo - the netherlands oils and fats industry (Pays-Bas) — Partner, associated partner, Autres, subvention : 0.0 €
- Institut Karolinska (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Hasselt (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 288540.0 €
- Nutricia Research (Netherlands) (Pays-Bas) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Lorraine (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Eutox -work group (european uremictoxins (eutox) work group) e.v (Allemagne) — Partner, associated partner, Autres, subvention : 0.0 €
- Jena University Hospital (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 290272.32 €
- Université de Skövde (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Berne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Scicross ab (Suède) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 324630.0 €
- German Research Centre for Artificial Intelligence (Allemagne) — Partner, associated partner, Recherche, subvention : 0.0 €