Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet STABREP (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : CLOSED

In this project, I will establish new connections between cluster algebras, mirror symmetry and representation theory through the introduction of geometric models. Mirror symmetry is a natural phenomenon, first observed in superstring theory, consisting of two main approaches: the A-model, focused on the symplectic side of a Calabi-Yau manifold X, and the B-model, focused on the complex side of the manifold. Mirror symmetry is a duality between the two models. Based on this, Kontsevich formulated his famous homological mirror symmetry conjecture for categories. In this conjecture, the A-model is the Fukaya category of X, and the B-model is the derived category of coherent sheaves of X^. Cluster algebras were introduced in the early 2000s to provide a combinatorial framework for dual canonical bases. Many new ideas in representation theory have their origin in cluster algebras, bringing together category theory, particularly Calabi-Yau categories, combinatorics and the geometry of Riemann surfaces. In exciting recent developments cluster theory and homological mirror symmetry have been linked through scattering diagrams, opening up both theories. In this project, I will study the connections between cluster combinatorics and scattering diagrams through Calabi-Yau algebras, which appear in a natural way in cluster theory and mirror symmetry. I will develop geometric models for the representation theory of Calabi-Yau algebras encoding, in particular, their (co)homology. This will lead to a complete understanding of these algebras and their role in the mirror symmetry program. Dimer models are intrinsically linked to both cluster algebras and mirror symmetry. As part of my project, I will generalize dimer models to the general setting of special multiserial algebras. Both Calabi-Yau algebras and special multiserial algebras are of wild representation type and my geometric models will lead the way to an understanding of stability conditions for wild algebras.

Mots clés : representation theory of algebras, cluster algebras, surface geometry, cohomology theories, homological mirror symmetry, dimer models, geometric models

Participants :
- University of Leicester (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 212933.76 €
Projet InEr-SICKLE (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

In this project, I will investigate ineffective erythropoiesis as a contributing factor and potential therapeutic target in the pathogenesis of sickle cell disease (SCD), one of the most prevalent genetic disorders in man and a global health problem. I will employ cutting-edge proteomic and genomic approaches to investigate in detail deregulation of the master erythroid transcription factor GATA1 as a result of oxidative stress in sickle red blood cells, as the basis for ineffective erythropoiesis in SCD. I will also investigate whether restoring GATA1 functions can alleviate ineffective erythropoiesis, thus providing alternative therapeutic opportunities in treating SCD. Lastly, I will generate novel cellular models for SCD from patients that can be used in dissecting the pathophysiology of SCD and in screening for agents that can alleviate IE and sickling. My project will generate novel insight into SCD pathogenesis and tools that can lead to the development of novel therapeutic approaches. My background in SCD cellular pathophysiology is highly complementary to those of my supervisors, Prof. John Strouboulis who is an expert in GATA1 functions in molecular erythropoiesis and Prof. David Rees, who is a world leading clinician in pediatric sickle cell disease. I stand to benefit greatly by receiving excellent training in -omics, functional assays in molecular erythropoiesis and in clinical aspects of SCD, that will enable me to progress into a career as an independent investigator.

Mots clés : sickle cell disease, hematology, erythropoiesis, transcription factors

Participants :
- University of London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 212933.76 €
Projet COMETE (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks - Industrial Doctorates
Panel : Information Science and Engineering
Statut du projet : SIGNED

In this project, we aim at building a computational framework and a network of competence to extend the applicability of state-of-the-art formulations to industrially-relevant multiphase turbulent flows. We focus on applications characterized by the transport of particles/droplets in two-phase flows with gas-liquid or liquid-liquid deformable interfaces, which are ubiquitous in process, chemical, and power engineering. The targeted applications are at the crossroads between academic research and practical concerns (e.g. particle deposition in boiling flows, droplet coalescence/breakup in emulsions, freezing/defreezing in heat pipes or changes in two-phase flow patterns) and their modeling in an industrial context represents a major challenge. This is due to the complexity arising from the co-existence of different phases, but also to a lack of cross-fertilization between academia and industry: Several methods and ideas exist but their application is often limited to flows of academic interest, with scarce transfer of skills, poor experimental validation and, most importantly, no unified framework into which existing methods could be cast. This represents a serious obstacle to industrial developments since engineers and practitioners can be unaware of which method to use and in need of support. To build the new framework, we consider emerging complementary methods, including Smoothed Particle Hydrodynamics and Phase Field. COMETE leverages on the complementary expertise of the industrial and academic partners to ensure successful combination of technology-driven objectives and original research developments. To this aim, we will build an international network of excellence by putting forward synchronized training-through-research and training-on-the-job activities, and we will form PhD students fully capable of mastering the next-generation scientific methodologies for complex industrial applications of multiphase flow technology.

Mots clés : multiphase flow, multiscale modeling, process engineering, training through science, training on the job

Participants :
- Électricité de France (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- TU Wien (Autriche) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 264207.24 €
- Polish Academy of Sciences (Pologne) — Partner, beneficiary, Recherche, subvention : 227478.6 €
- Euro Heat Pipes (Belgium) (Belgique) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Esteco spa (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Udine (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 261499.68 €
Projet OHPF (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

In this project, we will (1) investigate the ability to use the log of emotional states captured with wearable trackers for improving affective forecasting abilities of people, (2) build a tool for managing personal finance that integrates prediction analytics, and (3) evaluate if accurate expectations about purchases increase happiness of individuals. Happiness and wealth are important metrics in our society with no simple relationship between them. One explanation for why money does not buy happiness is that individuals often have imprecise expectations about things they buy: imprecise forecasting of the nature, intensity and duration of an affective response derived from a purchase. Current technology enables people to track how money is spent to help take control of one’s personal finance, balancing income and expenses, and achieving financial goals. A similar trend is present in tracking of emotional well-being of people through novel wearable sensors emerging from the Quantified Self movement. This project harnesses these unique and timely developments in improving the positive impact wealth can have on happiness. We will improve the accuracy of affective forecasts about future purchases by keeping history of emotional states and associated spending, performing prediction analytics based on the collected data, and providing feedback about anticipated affective value of the purchases. Such a feedback is expected to remedy the biases in affective forecasting that people are prone to and can be integrated into the tools for managing personal finance.

Mots clés : well being, emotion, happiness, finance

Participants :
- University of Bristol (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet OrganoMag (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

In this project, we will develop new single-molecule magnets (SMMs) that combine the strong magnetic anisotropy of lanthanide ions with a series of novel radical ligands. Highly unusual di- and tri-metallic Ln-SMMs are proposed in which the metals are bridged by radicals with heavy Group 15 donor atoms (i.e. the pnictogens, phosphorus-bismuth). The SMM field is dominated by systems with diamagnetic ligands: our radical ligands are novel, hence their applications in single-molecule magnetism will be unprecedented. We will exploit the rich electrochemistry of the proposed ligands: our DFT calculations show that the target heavy pnictogen radical anions have huge spin densities on the donor atoms, hence the diffuse unpaired spin of the radicals will provide a way of switching off the quantum tunnelling mechanisms that otherwise prevent hysteresis. Ultimately, this project introduces the potential for creating SMMs that show hysteresis at unprecedentedly high temperatures.

Mots clés : organometallics, molecular magnetism

Participants :
- University of Manchester (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet NONLOCAL PHENOMENA (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : CLOSED

In this proposal I aim to study three different phenomena in elliptic problems of nonlocal character, with the fractional Laplacian as main operator. First, we will study concentration phenomena for fractional-type Schrödinger equations, a line of research that has been recently open by authors like Valdinoci, Dipierro, del Pino, Dávila or Musso, among others. With their works as starting point, we will study existence and characterization of multi-peak solutions for the Dirichlet problem, analysis of the shape of concentration in Neumann problems and extension to general nonlinear problems in both cases. The second goal consists on developing nonlocal analogues of the Bahri-Coron methods to analyze how the solvability of the fractional critical problem (in the sense of the Sobolev embedding) depends on the topology of the domain. By means of approximation and deformation arguments we want to prove existence of solutions if the homology of the domain with Z2 coefficients is not trivial (for instance in n=3 if it is not contractible). Finally, in the third problem we will focus on the study of surfaces with constant nonlocal mean curvature. Based on the Aleksandrov-type results obtained by Cabre, Fall, Weth and Solà-Morales we aim to establish the existence of global continuous branches of nonlocal Delauny hypersurfaces and to analyze their limiting configuration. To achieve these goals I plan to use a 24-months fellowship at Universitá degli Studi di Milano (UMIL, Italy) with a 5-months secondment at Universitat Politècnica de Catalunya (UPC, Spain) under the supervision of E. Valdinoci and X. Cabré respectively, world experts in the field. The multidisciplinarity, originality and innovative character of the proposal, as well as the possibility of collaborating with both professors, will place me at the end of the period of fellowship as a solid independent researcher with a high expertise level in nonlocal partial differential equations.


Participants :
- University of Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 168277.2 €
Projet PHOTOBIOCATH-CO2 (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

In this proposal, organic, carbon nanotubes fibres (CNTf) or reduced graphene oxide (RGO),and inorganic, p-type semiconductors or their nanocomposites, nanohybrids are systematically combined in multistep synthetic methods to fabricate novel photocathodes, as well as some counterparts of them (for the purpose of comparison), for studying their efficiency in a photoelectrochemical (PEC) for CO2 reduction to formate. One of the key elements of this hybrid photoelectrode is the presence of the enzyme formate dehydrogenase (FDH) anchored on a highly conductive carbon-based nanomaterial (CNTf or RGO) film at the top of the light absorber that catalyzes the reaction to reduce CO2 to formate. The carbon-based support will provide fast charge transfer from the semiconductor to the biocatalyst, without altering the FDH catalytic center. In other words, for ensuring electron transport between the two key photocathode components), in this project, a carbon nanotube fibre (CNF) or RGO interlayer film will be exploited between the photoactive material and FDH co-catalyst for the first time as a highly conductive platform, which is a prerequisite for technical applications to prevent short-circuiting and leaching of the biocatalyst or mediator species. After evaluation of their PEC activity, the relationship between their structure, synthesis method, and morphology on the one hand and their PEC activity on the another hand will be correlated and discussed. The aim will be selecting the best option as photocathode for designing a photoelectrochemical CO2 reduction reaction (PEC-CO2RR) cell with high efficiency and stability that can alleviate the pollution caused from fossil fuels use. In this way, the design of a photoelectrochemical CO2 reduction reaction (PEC-CO2RR) cell can be accomplished for producing formate, a valuable chemical product due to its wide range of applications.


Participants :
- Spanish National Research Council (Espagne) — Coordinator, beneficiary, Recherche, subvention : 160932.48 €
Projet ReSound (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

In times of socio-political upheaval, reconstructed religious identities reshape ideas, communities, and culture. In early modern Europe, the Reformation shattered networks of belief. Reformers rebuilt communities by revising traditional forms of worship and their music. Plainchant was integral to their efforts. It was inexorably tied to liturgies, and its localised melodies crafted and communicated religious identities. Chant was especially essential when confronting powerful religious influencers: the saints. Lutherans reinterpreted saints as accessible, gendered exemplars of the well-ordered protestant life. The use of plainchant provided a link with the past, but its textual and melodic revision emphasised the devotional divide. Despite the crucial role of musical saints’ cults in rebuilding religious identities and networks, the extent of their influence is unknown. This project employs an innovative transregional and interconfessional approach to investigate the imposition, individuation, and intersection of identities in liturgies shared by Lutherans and Catholics. Using evidence from sermons, literature, and art, the chanted celebrations will be reintegrated into worship. The promotion of idealised femininities and masculinities in text and music will be examined in the five major Lutheran chant compendia. The adoption and adaptation of these identities will be explored in imported and local liturgical books used in the multicultural, heterodox trade centre of Tallinn. The oppositional interrelation of reshaped Catholic and Lutheran identities will be analysed in the Feast of the Visitation, which both groups revised. This research will demonstrate how musical saints’ cults refashioned identities and connected communities after the Reformation. It will thus enhance and benefit interdisciplinary studies of identity, worship, and reform. It will also provide new insights on the socio-political and cultural changes that reshaped Europe and still resound today.

Mots clés : music plainchant reformation counter reformation saints worship lutheran catholic liturgy ritual identity transregional baltic germany book gender education printing class memory virgin mary

Participants :
- Uppsala University (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191852.16 €
Projet HEAR-ECO (Horizon 2020, appel à projets 2017)
Action : Doctoral Networks - Industrial Doctorates
Panel : Life Sciences
Statut du projet : CLOSED

In today’s ageing European population, hearing impairment is an increasing concern for public health and societal participation. The percentage of hearing-impaired people will rise from around 16% of the adult EU population now to around 40% in 2030. Hearing aid (HA) fitting is the most widely prescribed solution for hearing impairment. However, only around 30%-40% of adults with hearing impairment use HAs in daily life. One of the reasons for this is that methods used to develop and evaluate HAs are still not based on conditions in which HAs are actually used. Thus the potential of improved HA technology to meet the needs of individual users in their daily lives is acutely under-exploited. The science in HEAR-ECO will help to facilitate the paradigm shift which is needed to bridge the gap. Such a paradigm shift requires a new generation of hearing scientists that are able to integrate conventional Audiology with Motivational and Social psychology (motivation to listen, cognition), Psychophysiology (pupillometry, PEP, EEG), and HA technology. HEAR-ECO will train six ESRs capable of spanning these disciplines and translating their knowledge into innovative technological HA evaluation and development. The six ESRs will be trained through local training at academic partners in The Netherlands and the UK and secondment to one of the largest hearing aid manufacturers in the world in Denmark – and through network wide training, including an associated partner in Liverpool. The ESRs will be capable of developing and combining new tools and outcome measures for realistic everyday communication and translating this to innovative technological HA evaluation and development.

Mots clés : hearing aids, pupillometry, listening effort, ecologically valid methods

Participants :
- Liverpool John Moores University (Royaume-Uni) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Oticon (Denmark) (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 621548.65 €
- University of Nottingham (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 505190.87 €
- Amsterdam University Medical Centers (Pays-Bas) — Coordinator, beneficiary, Recherche, subvention : 510748.56 €
Projet VALENCE-REPLAY (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

In today’s societies, adequate rest takes second place to busy professional and personal schedules. It is known that lack of rest and sleep affects mental health, emotional regulation and daytime function. Such symptoms translate to increased healthcare costs and losses in workplace productivity. How emotional regulation processes interact with sleep and associated memory consolidation functions is not well understood. In addition to increasing basic understanding of brain function, addressing this knowledge gap can help shape therapeutic approaches for mental wellbeing and contribute to EU’s H2020 goals of smart, sustainable and growth. VALENCE-REPLAY will provide a building block towards addressing this knowledge gap through experiments in behaving rodents. The questions to be addressed in this fellowship are: Are memory consolidation processes during sleep preferentially shaped according to the valence of prior experience? If this is so, how is this accomplished at a mechanistic level? The work will use modern electrophysiology and optogenetic techniques to probe functional interactions of brain areas that mediate emotion (amygdala) and memory (hippocampus) and the role of these interactions in memory replay and consolidation during sleep. The project will also lead to fabrication of a new tool, parylene-based multisite neuronal recording probes that will permit tracking single neuron activity from the ventral hippocampus for adequate lengths of time to address the outlined research goals. The fellowship will shed light on how emotions shape memory processes during sleep, but will also afford a committed and experienced researcher the opportunity to acquire advanced training at leading European neuroscience institutes while forming a strong scientific network with leaders in the field. Through VALENCE-REPLAY, Dr Perentos will develop into an independent researcher, able to lead his own research group and achieve high impact research in systems neuroscience.

Mots clés : neuronal ensembles, single neuron recordings, optogenetics, memory consolidation, sleep, replay

Participants :
- Ludwig-Maximilians-Universität München (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 171460.8 €