Projet ARISE (Horizon 2020, appel à projets 2018)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

The Overarching Objective for this consortium is to establish an inter-agency and multidisciplinary staff exchange programme between researchers, technical and administrative staff interaction within EU institutions as well as reaching out to non-EU countries in Africa, Lebanon and US in order to foster sharing of best practice in Newborn Screening, diagnosis and treatment of Sickle Cell Disease (SCD) leading to improvement in overall disease outcome. Using implementation science strategies for this consortium to foster partnerships and the establishment of patient database, registries and a sustainable service for people living with the disorder. Primary Objectives: - To evaluate the prevalence of sickle cell disease among populations in consortium member countries and identify specific haemoglobin genotypes and phenotypic presentations; - To establish laboratory diagnosis and quality assurance systems for population screening and setting up of SCD national prevention programmes; - To test the feasibility for establishing newborn and early infant screening for SCD in consortium participants; - To establish treatment protocols for common complications -acute and chronic pain, stroke, infections, severe anaemia as well as transition from paediatric to adult care, health promotion strategies and nutrition. In order to achieve these objectives, we designed the following WPs: Scientific Coordination and Project Management Implementing eHealth technologies to support a Newborn screening programme in EU, African Countries and Lebanon. Improving laboratory diagnosis and quality assurance systems for population screening. Newborn SCD screening, screening for neurocognitive complications, clinical care and antibiotic prophylaxis Enhancement of SCD management through training in molecular diagnostic techniques and Genetic Counseling for haemoglobinopathies and performance of epidemiological and Training in Research and academic leadership. Communication and dissemination

Mots clés : sickle cell disease, stroke prevention, sickle cell nephropathy, epidemiology and population genetics

Participants :
- Azienda Ospedaliera di Padova (Italie) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Ministry of Health (Zambie) — Partner, organization partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Royal College of Pathologists (Royaume-Uni) — Partner, beneficiary, Autres, subvention : 299000.0 €
- University of Abuja (Nigeria) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Guy's and St Thomas' NHS Foundation Trust (Royaume-Uni) — Partner, beneficiary, Recherche, subvention : 469200.0 €
- Cyprus Institute of Neurology and Genetics (Chypre) — Partner, beneficiary, Recherche, subvention : 220800.0 €
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 202400.0 €
- University of Illinois System (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Ahmadu Bello University (Nigeria) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Campania "Luigi Vanvitelli" (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 96600.0 €
- University of London (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 170200.0 €
- Instituto Politécnico de Lisboa (Portugal) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 156400.0 €
- Lagos State University (Nigeria) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Instituto nacional de investigacao em saude (Angola) — Partner, organization partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Gianni Benzi Pharmacological Research Foundation (Italie) — Coordinator, beneficiary, Recherche, subvention : 147200.0 €
- American University of Beirut (Liban) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Padua (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 138000.0 €
- University of Udine (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 82800.0 €
- Geniko laiko nosokomeio athinon*general hospital of athens laiko (Grèce) — Partner, beneficiary, Recherche, subvention : 0.0 €
- University of London (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 124200.0 €
- Strathmore University (Kenya) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €