Projet ProtAIomics (Horizon Europe, appel à projets 2024)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

ProtAIomiProtAIomics is a European Innovative Doctoral Network aimed at training the next generation of computational proteomics researchers by integrating advanced artificial intelligence (AI) methods with proteomics. Computational proteomics stands at the forefront of cutting-edge life science research, utilizing advanced data analysis and AI to decode the complex interplay of proteins in biological systems. Proteins, typically referred to as the workhorses of biological systems, are central to understanding cellular functions, disease mechanisms, the mode of action of drugs, and drug response. The network brings together 15 beneficiaries and 9 associated partners from diverse academic and non-academic sectors, including university hospitals, SMEs, and large companies, to tackle key challenges in the computational proteomics field. The network focuses on three main research objectives: (RO1) developing AI-assisted algorithms to maximize the extraction of high-quality information from raw mass spectrometry (MS) data; (RO2) creating advanced tools to transform this data into deeper biological knowledge through AI-driven models; and (RO3) applying this knowledge to generate actionable insights, such as precision drugs and clinical biomarkers, with a focus on advancing therapeutic applications. Through cross-disciplinary collaboration, ProtAIomics will bridge gaps in current proteomics research by enhancing data utilization, improving understanding of protein functions, and advancing AI tools for clinical applications. The network will provide comprehensive training, equipping doctoral candidates with exceptional AI application and development skills in an intersectoral, interdisciplinary and international setting, and improving their future employability. ProtAIomics is committed to fostering responsible research and innovation (RRI), ethics, effective science communication, proficient data management, and advance towards delivering solutions to societal challenges.

Mots clés : computational proteomics, artificial intelligence, protein function, structural proteomics

Participants :
- Centro de Regulación Genómica (Espagne) — Coordinator, beneficiary, Recherche, subvention : 282188.16 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 314669.16 €
- Institute of Microbiology (Rép. Tchèque) — Partner, beneficiary, Recherche, subvention : 280022.76 €
- Université technique du Danemark (Danemark) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 335890.08 €
- Bruker (Germany) (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University Hospital Heidelberg (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 290272.32 €
- Institut de recherche en biomédecine (Espagne) — Partner, beneficiary, Recherche, subvention : 282188.16 €
- AstraZeneca (United Kingdom) (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Institute of Molecular Biology (Allemagne) — Partner, beneficiary, Recherche, subvention : 290272.32 €
- University of Applied Sciences Upper Austria (Autriche) — Partner, beneficiary, Recherche, subvention : 302542.92 €
- Université technique de Munich (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 290272.32 €
- Université de Linz (Autriche) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Charles de Prague (Rép. Tchèque) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Toulouse (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Johannes-Gutenberg de Mayence (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Wellcome Trust (Royaume-Uni) — Partner, beneficiary, Recherche, subvention : 348738.12 €
- Laboratoire européen de biologie moléculaire (Allemagne) — Partner, beneficiary, Recherche, subvention : 348738.12 €
- École polytechnique fédérale de Zurich (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Pompeu Fabra (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 282188.16 €
- Msaid gmbh (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Cambridge (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 348738.12 €
- Université de Heidelberg (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- KTH Institut royal de technologie (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 324630.0 €
- Université de Tampere (Finlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 314524.8 €