Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet AE-FUN (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Catalysis is a powerful tool to address profound challenges in Europe’s energy transition. However, many current catalytic systems face important limitations in relation to activity, selectivity, or cost efficiency. Particularly, the production of ammonia relies upon the century-old energy-intensive Haber-Bosch process, which is estimated that consumes up to 3% of the global energy produced every year. This EU-funded AE-FUN project will develop innovative systems based on earth-abundant, readily available alkaline earth metals for the challenging conversion of dinitrogen into ammonia and other nitrogen-containing valuable chemicals. This will be achieved by harnessing the unexplored modes of cooperativity between transition metals and low-valent alkaline earth elements. We envision that unusual participation of d the orbitals from the Ae element and the redox activity of transition metals will give place to unseen synergies that will facilitate the activation of highly challenging substrates (N2, CO2, CO, H2) and their functionalization.

Mots clés : main group chemistry, bimetallic chemistry, alkaline earth metals, nitrogen reduction, homogeneous catalysis

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 172018.56 €
- Institut de technologie du Massachusetts (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet TERRA (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Our understanding of processes governing effusive and explosive eruptions has improved over the past decades, but understanding the nature of eruptive activity using seismicity is poorly constrained. Volcanoes produce a wide range of unique seismic signals, providing information on source depth, fluid migration and subsurface processes and structures. Hence, volcanic seismicity is a useful tool used by observatories to understand activity throughout eruptive and rest periods. Many volcanoes show a mixture of explosive and effusive activity, proving difficult for hazard assessment and risk mitigation due to the differing impacts of eruptive style. Mt. Etna is one of the most active volcanoes in the world, and produces a range of eruptive styles, with eruptions varying in length from days to months. Records of eruptions at Mt. Etna date back to 1500 BCE, with a noted increase in volcanic activity over the past 30 years. This high eruptive rate, longevity and variations in eruptive style provides an ideal location to understand links between eruptive processes and seismicity. A substantial seismic network operated by INGV has been in place since 2000, providing a vast catalogue of seismicity. The proposed project 'TERRA', will work alongside INGV to Tackle seismicity at Etna using Repeating sources, Relocations and Ambient noise monitoring. Repeating earthquakes are spatially localised groups of events that are commonly recorded at volcanoes with each type of signal. Ambient noise monitoring will allow a continuous record of velocity changes through several eruptions; this will complement results from relocated and categorised seismicity to further develop understanding of processes before eruptive episodes. The objective of this proposal is to provide novel quantitative constrains on the relationships between seismicity and volcanic processes that govern eruptive styles at Mt. Etna by looking at the temporal evolution of seismicity since 2000.

Mots clés : seismology, volcanology, volcanic processes, seismic signals, velocity changes, repeating sources, earthquake relocation

Participants :
- Université de Padoue (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 265099.2 €
- Institut de technologie du Massachusetts (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet SULBOR (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Sulfur(VI) compounds like sulphonamides, sulfonimidamides and sulfondiimidamides are increasingly used for the design and development of pharmaceuticals and agrochemicals. However, despite their societal relevance, the preparation of these derivatives, especially sulfonimidamides and sulfondiimidamides, is still very challenging. Current methods relys on the use of toxic and pyrophoric reagents and often offer minimum versatility for divergency and diversification.  The development of a general, sustainable and divergent approach to these molecules has the potential to impact the discovery and the evolution of high-value materials.  In this work we propose a fundamentally novel approach to access sulfonimidamides and sulfondiimidamides by developing an innovative three-component coupling reaction between commercial alkyl halides, N-nucleophiles and sulfur(VI) linchpin reagents. The methodology will use boryl radical-mediated halogen-atom transfer to convert the alkyl halide into the corresponding radical for a sequential reaction with the sulfur(VI) linchpin and then, aided by a copper catalyst, with the N-nucleophile.  The development of this strategy will provide an innovative and streamlined approach towards molecules of high academic and industrial interest but that are still very difficult to access.  This research squarely fits within the expertise of the Leonori group in the generation and use of boryl radicals in synthesis and catalysis.  The completion of such an innovative and ambitious project at RWTH Aachen University will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance the Researcher future career following the training plan envisioned.

Mots clés : halogen atom transfer boryl radical, sulfur vi molecules, radical cascade, copper catalysis

Participants :
- Université technique de Rhénanie-Westphalie à Aix-la-Chapelle (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 202125.12 €
Projet QuantumTuningABC (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

The second quantum revolution targets applications in quantum computation, cryptography, and sensing. Materials with strongly correlated quantum phenomena as unconventional superconductivity, fractional charge or topologically protected states are promising candidates. In searching for materials with robust and controllable correlated phases, rhombohedral graphite (RG) stands out due to its particularly simple crystal structure. It is readily available, exceptionally disorder-free, tunable and integrable into manufacturing processes. RG consists of individual graphene layers stacked in the metastable, but robust ABC order that naturally leads to a correlated surface state. Indeed, multiple peculiar quantum states have been found in RG, e.g. the fractional quantum anomalous Hall-effect or various unconventional superconducting phases. However, the state-of-the-art samples are limited to thicknesses of 5 graphene layers. This is detrimental, since the electronic density of the correlated flat band increases with layer thickness promising more robust and distinct phases in thicker samples. The Researcher has recently developed methods to reliably fabricate and identify large, perfectly ABC-stacked graphite flakes up to 12 layers. In this project, we will uncover and tune correlated quantum phases in the largely unexplored thickness range of 6-12 layers. The project combines the singular expertise of the Researcher in sample preparation with the one-of-a-kind equipment of the Host. The scanning tunneling microscopy (STM) technique enables the direct mapping, thus visualizing the correlated electronic phases (magnetic or superconducting states, and perhaps fractional quantum anomalous Hall phases) at the atomic scale. This will facilitate the understanding of new quantum phases of matter. Moreover, the targeted electric switching between different correlated electronic states will potentially enable novel applications using RG, e.g. for topological quantum computing.

Mots clés : 2d materials, abc graphite, rhombohedral graphite, scanning tunnelling microscopy, induced quantum phase transitions, fractional quantum anomalous hall effect, superconductivity, magnetism

Participants :
- Université technique de Rhénanie-Westphalie à Aix-la-Chapelle (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 108982.56 €
Projet CYBO (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Functionalized amines are high-value materials with numerous applications as therapeutic agents, agrochemicals and organic materials. The development of strategies for enabling the fast and divergent synthesis of these material can have a positive impact to our ability to discover, manufacture and evolve molecules of high-relevance to our society.  In this proposal we present an innovative approach for the functionalization of homoallylic amines based on their coordination borane (BH3). This will provide access to novel boryl radical species that we will exploit in cyclization-functionalization cascade. This novel reactivity mode will convert the homoallylic amine into a cyclic borylated and functionalized building block that can be further diversified across the sp3 C–B bond by oxidation or Suzuki-Miyaura cross-coupling.  Overall, this strategy will constitute a divergent platform for the diversification of high-value amines and also a novel retrosynthetic tactic for the preparation of high-value and structurally complex drug analogues. This research squarely fits within the expertise of the Leonori group in the generation and use of boryl radicals in synthesis and catalysis.  The completion of such an innovative and ambitious project at RWTH Aachen University will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance the Researcher future career following the training plan envisioned.

Mots clés : boryl radicals, radical cyclization, radical cascade, photoredox catalysis, cross couplings

Participants :
- Université technique de Rhénanie-Westphalie à Aix-la-Chapelle (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 217965.12 €
Projet mArSTED (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

ADP-ribosylation (ADPr) is a key post-translational modification catalyzed by the ADP-ribosyltransferase (ART) superfamily, including poly-ADP-ribose polymerases (PARPs), which, despite their name, can transfer either a single (mono-ADPr) or multiple (poly-ADPr; PAR) units of ADP-ribose to their targets. This process occurs in response to various biological and pathological stimuli, regulating numerous cellular functions. For many years, research in the ADPr field focused primarily on poly-ADPr PARPs, often overlooking the physiological importance and therapeutic potential of mono-PARPs. Recently, the development of new reagents, including versatile antibodies to detect mono-ADPr, provided essential tools to finally explore this elusive modification. Emerging evidence, partly obtained by using these antibodies, suggests that mono-ADPr responses could be promising therapeutic targets for immune-related diseases, pushing mono-ADPr into the spotlight. However, this growing pharmaceutical interest contrasts with our limited understanding of the molecular mechanisms and biological functions of mono-ADPr and the catalyzing enzymes. In this MSCA project, I aim to shed light on the functions of the underexplored mono-ADP-ribosylation by pioneering the development of super-resolution microscopy methods to visualize mono-ADPr localization across different cellular structures. Through this cutting-edge approach, my research will provide unprecedented insights into the spatial dynamics of mono-ADPr, potentially uncovering novel aspects of its functional roles in cells and providing powerful new methods for the ADP-ribosylation field. Additionally, I will investigate the crosstalk between two PARPs that, according to preliminary data from the host lab, may collaboratively mediate ADPr at the nuclear pore complex, providing insights into the molecular mechanisms underlying the findings from our microscopy studies.

Mots clés : parps adp ribosylation

Participants :
- Université de Cologne (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 202125.12 €
Projet PANATURE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : TERMINATED

Conservationists often use ‘historical’ arguments to justify their visions of which groups of human and non-human species should live where and how. Imagined pasts are central to influential concepts and practices of conservation, such as re-wilding, species re-introduction or landscape restoration. These narratives range from vague references to past equilibriums, that need to be saved, to more specific baselines of past distribution of certain species, that need to be restored, to the re-creation of specific past landscapes in new settings. Historians have hardly contributed to these historicized arguments. Following recent calls for conservation humanities, I apply historiographical methods to engage with conservationists’ ideas of past human-wildlife-land interactions and practices in Southern Africa and the European Alps. Firstly, I analyze, contextualize and compare how conservation organizations use imagined past human-wildlife-land relations and develop a typology of historical conservation narratives. In Southern Africa, conservationists present “Africans” as naturally knowing how to live in their environment or as a threat to nature. In Europe, conservationists’ narratives present historical people as experts or masters of nature. Secondly, I research specific historical moments in both regions, to juxtapose conservation narratives with localized analyses of historical changes in human-wildlife-land relations. Thirdly, by combining critical historical analyses of cases in the Global South with those of Europe, I challenge powerful conservation narratives that often perpetuate global power structures. By this, I critique ongoing conservation debates and practices, and offer novel perspectives of multi-species pasts. A thorough understanding of these pasts is crucial for coping with immense present and challenges in the light of the ongoing climate crisis, as for example formulated in the COP15 agreement to conserve and/or restore 30% of the world’s surface.

Mots clés : conservation humanities environmental history conservation narratives human wildlife land relations sothern africa european alps

Participants :
- Université de Cologne (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 173847.36 €
Projet TureckBachXXI (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

J.S. Bach’s musical legacy is astonishingly rich. We have been responding to his music for more than 300 years. The American keyboardist Rosalyn Tureck (1913-2003) devoted more than six decades to performing, researching, teaching, and writing about Bach’s works, as well as music and arts in general. She has left an abundant heritage on performance practice and scholarship for those who seek to understand, perform, and communicate Bach’s music. This heritage remains mostly unrevealed. Bringing together efforts from music performance, musicology, aesthetic, social studies, new music technologies, and composition, the TureckBachXXI project aims at gathering, exploring, and questioning Tureck’s ideas for Bach performance in the aesthetic, cultural, social, and technological mindset of the 21st century. The main outcome of this project will be a commented edition of Rosalyn Tureck’s ideas and findings on concepts, performance practices and techniques, and stylistic prospects involved in the realization of Bach’s music, and its connections with the music of today. This will be useful not only to artist performers, but also to musicologists, composers, and all enthusiasts interested in Bach’s legacy, as well as for the evolution of music and the arts. In addition, this project investigates musicological/performance questions opened by Rosalyn Tureck that will bring new perspectives to performers as well as to researchers and Bach enthusiasts. Finally, the project questions the vitality and the longevity of a music of a past era in the technological, cultural, aesthetic, and social environment of a new music era. This will result in particular in a series of interviews with composers of today nourished with questions raised by Rosalyn Tureck. Testimonies about Rosalyn Tureck from the remaining people who worked with her will also be collected. This interdisciplinary project opens new perspectives in the fields of Bach studies and music performance.

Mots clés : music, johann sebastian bach, rosalyn tureck, musicology, piano, arts, performing arts, music performance, life long learning, contemporary music, aesthetics, 21st century

Participants :
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Leipzig (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 289407.84 €
Projet SCIMITAR (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Our cultural heritage is our shared past and should be preserved for future generations. In order to preserve an art object, it is not only essential to study its structure, creation, history, and significance, but it is also necessary to understand its past and current state as well as projected changes in the future. In the case of old paintings, this requires being able to correlate macroscopic observations with its chemical make-up at the microscopic level. Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) is a powerful chemical imaging technique, especially suited for heterogeneous systems such as paintings. ToF-SIMS can simultaneously localize and identify organic and mineral components and has the highest spatial resolution of all the molecular imaging mass spectrometry techniques. The sub-micrometer spatial resolution of ToF-SIMS is needed to investigate painting micro-samples that consist of sub-millimeter stacked layers of dried paint that contain both organic and inorganic ingredients. Case studies published over the last two decades attest to the potential of ToF-SIMS in providing information relevant for painting conservation. However, the resulting imaging datasets are very complex often causing a large proportion to remain unexploited. The high energy ion source of the instruments also causes larger biomolecules such as proteins to fragment, making it impossible to identify them. Meanwhile, a variety of protein-rich ingredients coexist and age in paintings, which means that identifying their nature would be extremely valuable to conservation experts. The proposal aims at tackling these weaknesses by developing methods to unambiguously identify the materials found in the heterogeneous microstructures of old paintings samples using a ToF-SIMS instrument with novel Tandem MS imaging capabilities as well as the development of a ToF-SIMS-based immunohistochemistry relying on metal-labeled antibodies to allow for targeted protein imaging.

Mots clés : imaging mass spectrometry, paintings, microstructure, antibodies, tandem ms

Participants :
- Université de Maastricht (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 187624.32 €
Projet GenPrISA (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

This research aims to retrace the intellectual genealogy of progressive Islam in the context of South Africa, observed from a transnational perspective; the Claremont Main Road Mosque in Cape Town (CMRM) is chosen as the case study. CMRM is a historical Capetonian mosque that, in the early 80s, became a nodal point in the transnational circulation of Muslim progressive intellectual discourses and practices. The mosque made world history on August 14th, 1994, when Amina Wadud was invited to deliver a sermon to the Friday congregation: it was the first time in modern history for a woman to do so. The term “gender jihad”, which the mosque's imam Rashied Omar coined in the aftermath of the event and that Wadud has since adopted and popularized, is now used worldwide as an alternative to “Islamic feminism" and yet the intellectual and historical landscape that shaped the action and the coinage of the term has received very little scholarly attention. Taking the "Amina Wadud moment" as a watershed date, this project this project intends to pursue two main objectives: 1. Retrace the intellectual development and historical circumstances that paved the way for this event 2. Explore the effects that the democratic transition and the subsequent years had on CMRM’s discourse By exploring the Claremont Main Road Mosque's post-Apartheid discourse in its five key dimensions (the empowerment of youth, the gender jihad, jihad against poverty, interfaith dialogue, and environmental justice), and by retracing its historical background and intellectual genealogy, this project aims to give a significant contribution to the field of modern Muslim intellectual and exegetical history. The value of this project is not only theoretical: it seeks to offer insights and recommendations that can guide policymakers and civil society organizations in fostering social justice and diversity and in contrasting religious illiteracy and radicalization.

Mots clés : islamic sermon khutba progressive islam gendered muslim discourses politicization of the mosque

Participants :
- Université de Rome « La Sapienza » (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 244030.44 €
- Université du Cap (Afrique du Sud) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €