Projet REGENERATE-IT (Horizon Europe, appel à projets 2021)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

The REGENERATE-IT Network brings together a full spectrum of disciplines – from fundamental to applied research – to train the next generation of researchers in regenerative biology and adjacent fields. While the natural regenerative ability of humans is limited, some animals have remarkable regenerative capacity. For example, planarian flatworms can restore all body parts from small pieces of tissue, salamanders can grow back lost limbs and repair damaged eyes, and zebrafish can regenerate their heart and fins. By identifying the common biological principles underlying the regenerative processes in these different animal models, we can learn a great deal on how to improve regenerative interventions in humans. Currently, regenerative animal models are studied in isolation, preventing the discovery of such shared mechanisms, and the REGENERATE-IT Network fills this gap. ESRs trained by REGENERATE-IT will obtain a broad and unique understanding of the fundamentals of regenerative biology and of the needs of research in regenerative medicine. The REGENERATE-IT Network therefore includes scientists working on regenerative model organisms such as flatworms, cnidarians, crustaceans, amphibians and zebrafish; stem cell scientists working on mouse and human models; scientists with impressive track records in translational research and experience with clinical trials; and experts in key technologies such as genomics, single cell sequencing, imaging and drug screening. REGENERATE-IT will train 10 ESRs and 1 associated doctoral researcher through research, secondments to other laboratories, consortium meetings, and workshops covering a wide range of topics. In addition to consolidating European strengths in regenerative biology, and training a cohort of next-generation scientists capable of cross-disciplinary research, REGENERATE-IT will combine and deliver theoretical and technological breakthroughs, and advance the frontiers of regenerative biology and medicine.

Mots clés : regenerative biology, tissue and organ regeneration, animal models, stem cells, single cell sequencing, live imaging

Participants :
- Université de Groningue (Pays-Bas) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- École normale supérieure de Lyon (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Pfizer (Netherlands) (Pays-Bas) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- University Medical Center Groningen (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 274370.4 €
- Sanquin (Pays-Bas) — Partner, associated partner, Recherche, subvention : 0.0 €
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 259437.6 €
- Société Max-Planck pour le développement des sciences (Allemagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Institut Karolinska (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 293709.6 €
- M Squared Lasers (United Kingdom) (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université d'Osnabrück (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 260539.2 €
- Université Monash (Australie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Manchester (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Berne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Biomed central limited (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- ZeClinics (Spain) (Espagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Single cell discoveries bv (Pays-Bas) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université Côte d'Azur (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- N.v. nederlandsch octrooibureau (Pays-Bas) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université Vie-Santé Saint-Raphaël (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université d'Oxford (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Plateforme europeenne des femmes scientifiques aisbl (Belgique) — Partner, associated partner, Autres, subvention : 0.0 €
- Université de Vienne (Autriche) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Hasselt (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 262620.0 €
- Université de Modène et de Reggio Emilie (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 259437.6 €
- Stichting world duchenne organization (Pays-Bas) — Partner, associated partner, Autres, subvention : 0.0 €
- Institut für Molekulare Biotechnologie (Autriche) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 225276.0 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 565387.2 €
- Université de Copenhague (Danemark) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 301788.0 €