Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet WEAP (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The Western European Acheulean Project (WEAP) aims to characterize the occupational pattern of western Europe during the Middle Pleistocene (MP) –700 to 300Ka–, through the study of Acheulean technology. Recent research has shown that the Atlantic seaboard is the most likely route for colonisation due to the more oceanic climate compared to eastern Europe and to the richer range of resources in coastal areas. Due to cyclical changes in climate with glaciations and interglacials, northern Europe was frequently depopulated and then recolonized through this period probably from source areas in southern France and Iberia. This route-way should therefore bear witness to the cultural links between north and south. From 1 million to 600,000 years ago there is evidence of brief pioneering events in north-west Europe with a small number of sites and small numbers of stone tool artefacts. After 600,000 year ago more sustained occupation is shown by the increase in sites and the much large stone tool assemblages. They also show technological innovation in the form handaxes and possibly in the use of fire, clothing and shelter, which led to the first sustained occupation of northern latitudes. Although there has been much research and new sites excavated over the last twenty years, there has been little integration between the work in Spain, Britain and France. Based on the applicant’s previous experience, WEAP proposes to create a common method of analysis for the study of six Middle Pleistocene sites from UK and France –in agreement with three Middle Pleistocene technologists–, the use of the experimental technology to complete the archaeological record, and the use of new methodological approaches, such as the 3D scanning technology as the most appropriated statistical analysis, to improve understanding of behavioural patterns in order to build models of human dispersals from south-west to north-west Europe.

Mots clés : prehistory, lower palaeolithic, western europe, acheulian, handaxe

Participants :
- British Museum (Royaume-Uni) — Coordinator, beneficiary, Recherche, subvention : 195454.8 €
Projet CEREBSENSING (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

The ability to perceive and understand the state of the surrounding environment and the own state is critical for next generation robotic systems. To that aim, the human brain is still far beyond current artificial systems performance due to its capability of processing huge amounts of heterogeneous sensorial data. Interestingly, the cerebellum has been shown to play a crucial role in the generation of dexterous movements as evidenced from cerebellar ataxic patients. Behavioural studies suggest that the cerebellum actively improves sensorial discrimination and proprioception thanks to the prediction of the sensorial consequences of actions. In the last decade, several forms of long-term synaptic plasticity have been observed within the cerebellum, suggesting that distributed plasticity could support the predictive action. However the way in which those mechanisms cooperate in order to improve the function of the whole cerebellar network is not completely understood. In this project, the candidate will develop a novel theory of sensorial information representation and processing based on the cerebellar architecture. The proposed model will make use of long-term synaptic plasticity mechanisms distributed along connections existing in the cerebellar input layer (granular layer) to iteratively create sparse representations of the information, allowing fast and effective learning in successive layers. The predictions extracted from this model will be useful to design new experimental protocols to unveil the cerebellar role in acting and sensing. By providing multiple relevant contributions across the spectrum of the H2020 objectives in terms of its potential to advance robotic manufacturing, brain processing understanding, and novel computing paradigms, this project will enable the candidate to enhance his position at the forefront of advances in this field.

Mots clés : neural plasticity, motor control, neural information coding

Participants :
- University of Granada (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 158121.6 €
Projet JAL (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The ability to perform joint (multi-person) actions such as ensemble music performance confers numerous benefits, from generating unique aesthetic experiences to enhancing affiliation with one’s co-actors. Co-actors must be able to accurately predict when one another’s actions will occur so that they can time their own actions accordingly. One question facing the field of social neuroscience is how co-actors learn to make accurate predictions about one another’s actions. The current project, JAL, launches one of the first systematic investigations of joint action learning to address this question on the levels of both brain and behaviour. The project will implement a series of empirical studies in which partners learn novel joint turn-taking tasks while electroencephalography (EEG) is simultaneously measured from both partners: Turn-taking tasks are optimal for measuring prediction processes because partners must be able to accurately predict when one another’s turns will end so that they can seamlessly alternate actions. Learning conditions will be manipulated across studies to address three primary questions: 1) Is there an identifiable neural marker of how well partners learn to predict one another’s actions? 2) Do partners learn to generate stronger predictions about actions that serve as relevant cues for interpersonal coordination relative to actions that do not? 3) Can partners acquire the ability to predict one another's actions in a task-general manner? Outcomes from these studies will provide novel insights into how humans learn to coordinate actions with one another and will pioneer methods of simultaneously measuring behavioural and neural activity from multiple individuals during action learning. The knowledge gained from this project will be critical not only for improving methods of teaching joint action but also for developing interventions for individuals with deficits in social motor coordination.

Mots clés : joint action, electroencephalography, music neuroscience, temporal prediction

Participants :
- Central European University (Autriche) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 139850.88 €
- Central European University (Hongrie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet InfoSeekDev (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The ability to search for information effectively and efficiently is central to academic and professional success. Understanding how children learn to seek information is a topic of immense importance for society, for parents, and for educators. Active learning – searching for information effectively and efficiently – requires the coordination of complex cognitive processes: the ability to generate, evaluate, test, and update one’s hypotheses about the world. Four skills critical for active learning develop between 3- and 10-years old: the ability to formulate effective questions from scratch, the ability to reason about uncertain events and to use that information to guide one’s search, the ability to adapt one’s search strategy based on feedback and task characteristics, and the ability to monitor the search process and stop searching when enough information has been collected. This project builds on this work to ask a critical but unanswered question: what factors support the development of these active learning skills and explain individual differences in them? Based on prior research, this project targets two factors: children’s cognitive skills and their socio-cultural environment. The first phase of the research is diagnostic and will explore using observational and correlational methods the associations and unique contributions of cognitive skills and socio-cultural input on children’s active learning skills. The second phase will use insights gained in Phase 1 to develop an intervention designed to boost children’s active learning skills. It will allow us to assess the causal impact of socio-cultural input and cognitive skills on the development of children’s active learning capacities by manipulating them experimentally. Because the acquisition of information seeking skills and the optimization of learning environments is critical to conceptual development in a variety of domains, findings promise to contribute both to psychological science and education.


Participants :
- Max Planck Society (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 171460.8 €
Projet AGePOP (Horizon 2020, appel à projets 2020)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

The advanced age population (>65y) makes up ~20% of the total population in Europe, is the main carrier of chronic diseases and the major end-user group of medications. Yet, despite an ageing society, these end-users are entirely disregarded in the drug development process, which considers only healthy adults aged 18-55. Effective absorption of oral drugs, which remain the preferred form of administration, relies on a sound knowledge of the physiological alterations associated with ageing and of the characteristics of the gastrointestinal (GI) tract in older subjects. Nonetheless, both the knowledge and the experts in this area are lacking. The AGePOP European Training Network (ETN) will boost Europe’s innovation capacity and leadership in oral drug development. Its multisectoral approach will train 11 Early Stage Researchers (ESRs) to become the future experts in drug development for the advanced age population, shedding a much needed light on the needs of our ageing society. With an open science philosophy and a multidisciplinary strategy, the ESRs will collect the first ever dataset of physiological characteristics of the GI tract of older people and geriatric patients, developing novel in vitro and in silico tools, e.g. a mobile test kit to evaluate gastric emptying kinetics and an absorption risk calculator to predict adverse effects from altered pharmacokinetics. Complementary training in transferable, business and wider horizon skills will equip the ESRs with an all-rounded skillset. AGePOP is a network of 6 Beneficiaries and 7 Partner Organisations from 5 European countries. Its 3 academic partners with research excellence in oral drug products synergise with renowned clinicians and researchers from 8 leading pharma companies and 1 SME specialised in ETN training. Building on long-standing collaborations, the consortium will provide 11 ESRs with a unique Europe-wide learning experience, preparing them to lead their future careers with confidence and success.

Mots clés : oral drug development, dosage form, absorption, geriatric patients, advanced age, biopharmaceutics, in vitro tools, pbpk modelling, gastrointestinal physiology, parkinson s, alzheimer s, diabetes

Participants :
- KU Leuven (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 768960.0 €
- Roche (Switzerland) (Suisse) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 281276.64 €
- Merck (Germany) (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 252788.4 €
- Bayer (Germany) (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 252788.4 €
- National and Kapodistrian University of Athens (Grèce) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 729052.92 €
- University of Greifswald (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 505576.8 €
Projet PurHumanDrome (Horizon Europe, appel à projets 2023)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

According to the WHO, in 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths. The proposed project fits perfectly into the Europe's Beating Cancer Plan, in particular the point "Diagnosis and treatment and quality of life of cancer patients". This project combines the expertise of scientists and academic centres from five different countries in three continents who are applying their knowledge at the frontiers of biology, chemistry, bioinformatics, biophysics and medicine to find a specific inhibitor for the ATIC enzyme involved in de novo purine biosynthesis. We have developed a number of new peptide-like compounds (and more compounds will be uncovered by bioinformatics tools) and will evaluate their efficacy in inhibiting the dimerisation of the enzyme ATIC monomers. The studies will also be conducted in cancer cell lines and in Drosophila flies. The outcomes can not only improve the health of society, but also provide new insights into metabolic pathways in cancer. The project will involve young and experienced scientists from EU countries, the USA and Australia. Scientists who have previously worked on the interactions of molecules in vitro will learn how to work with animal models and how to conduct in silico studies. Those who have previously used structural spectroscopy techniques in their work will learn physico-chemical methods, e.g. isothermal titration microcalorimetry ( ITC) and microscopic techniques. In addition, European scientists will have the opportunity to improve their ability to communicate and present their work results in English, to enter into new collaborations and to form their own international teams. Up-to-date information about the project will be published on the websites of all consortium partners involved in this project. We also plan to organise at least one live workshop. Every effort will be made to ensure gender balance at all levels of staff involved in the project.


Participants :
- Université d'État d'Erevan (Arménie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 23000.0 €
- Conseil national de la recherche (Italie) — Partner, beneficiary, Recherche, subvention : 18400.0 €
- Institut royal de technologie de Melbourne (Australie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Coastal Carolina University (Etats-Unis) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Université d'Opole (Pologne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 161000.0 €
Projet NANOTRIOSTEO (Horizon Europe, appel à projets 2023)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : SIGNED

NANOTRIOSTEO is a scientific cooperation project based on experimental and theoretical research of the surface iteractions on solid materials at nanoscale for improving materials for engineering applications. NANOTRIOSTEO will provide theoretical support for better understanding of process at the nanotribo interface developing models based on experimental information that provide feed-back to materials design. NANOTRIOSTEO will develop capacities for the study at the level of the Density Functional Theory and Molecular Dynamics of molecular aspects of nanotribology and oesteointegration phenomena in materials used for surgical replacement of hip and knee with an endoprosthesis. Modern materials science and in particular surface science is all about the molecular level knowledge of physical, chemical, and biological processes occurring in the nanometer scale vicinity of surfaces or interfaces. NANOTRIOSTEO will apply computer simulations methods that allow complementing experimental studies and interpreting at atomic scale the lubrication properties of different carbon nanostructures, SiCx/Steel and Ti oxides interfaces. Nanotribology is a key in understanding the first events of friction, wear and adhesion behaviours at solid/solid and solid/liquid interfaces of materials in relative motion. An exceptional expertise in theoretical physics and chemistry and simulations is an added value for understanding process at molecular level. NANOTRIOSTEO activities are linked to research as well as to education. Both of them will empower the cooperation among the partners involved. This project will allow the start of networking among the four participants; this cooperation will be strengthened due to the secondments that will be carried out during NANOTRIOSTEO. Furthermore, this project will be the foundation for future cooperation among the partners due to their interdisciplinary expertise and the synergetic approach to be used within this project.

Mots clés : molecular dynamics tribology coatings osteointegration dft biocompatibility surface adsorption

Participants :
- University of Caxias do Sul (Brésil) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Universidad Nacional del Sur (Argentine) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 216200.0 €
- Université de Ljubljana (Slovénie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 128800.0 €
Projet MET-EFFECT (Horizon Europe, appel à projets 2021)
Action : Staff Exchanges
Panel : Chemistry
Statut du projet : SIGNED

The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its ability to bridge chemical structure with a function, MET-EFFECT proposes brand new concept of novel multifunctional rhenium and iridium flavonoid complexes aimed to serve as metallodrugs and homogenous catalysts. The fusion of academic knowledge and industry-oriented perspective establishes a fruitful collaboration of an international and intersectoral profile. Well-recognized members of Consortium gains beyond the-state-of-the-art advances in bioinorganic chemistry by: a) developing novel Re and Ir complexes containing apigenin-like ligands, a natural bioactive flavone-type of molecules; b) determining the antitumor potential of newly synthesized Re(V) and Ir(III) complexes on a panel of various human cancer cell lines; c) evaluating the applicative potential of novel Re(V) complexes as homogeneous catalysts in OAT-inspired reactions (olefin epoxidation, oxoanions catalytic reduction and water oxidation). The structure and sentence of 7 work packages implemented through 37 secondments will enable the promotion of newly synthesized metal-based compounds in industrial environment for the sake of reaching their final applications. The widespread partnership creates an outstanding, R&I oriented ambient ensuring free knowledge sharing and career upgrade of the participating staff. By developing functional metal-based molecules, MET-EFFECT encompasses full human intellectual capacity capable to challenge technical, economic and environmental demands of wider society for applied but sustainable chemistry.

Mots clés : rhenium, iridium, flavonoid, synthesis, characterization, metallodrug, cancer, cytotoxicity, homogenous catalysis, water oxidation

Participants :
- Ist-id associacao do instituto superior tecnico para a investigacao e o desenvolvimento (Portugal) — Partner, beneficiary, Recherche, subvention : 128800.0 €
- Venusrouzes labsolutions (Bulgarie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 216200.0 €
- Innovative centre faculty of chemistry belgrade ltd (Serbie) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 170200.0 €
- Université de Graz (Autriche) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 124200.0 €
- Centre for innovative process engineering (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 124200.0 €
Projet Peace and Mobilities (Horizon Europe, appel à projets 2023)
Action : Staff Exchanges
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The research program seeks to provide a conceptualization of peace´s vision which provides new understandings for the conceptualization for peace beyond the absence of violence. These visions of peace are produced by people on the move. We did not found research available about this topic. We will fill a gap in the current research both peace-conflict studies and migrations studies about the role of people on move in construction of peace. Moreover, we want to track and analyze violence suffered by people on the move both on the way to their destiny and in societies which are not normally categorized as violent or conflictive. This is to des-sedentarize peace and violence studies in order to understand the way in which peace and violence are also mobilized.

Mots clés : mobilities peace studies memory studies media studies positive peace

Participants :
- Autonomous University of Chile (Chili) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Stichting herengracht 401 (Pays-Bas) — Partner, beneficiary, Autres, subvention : 115000.0 €
- Université de Guadalajara (Mexique) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Milan (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 331200.0 €
- Zaporizhzhya National University (Ukraine) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 285200.0 €
- Université nationale de Colombie (Colombie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université pontificale de Comillas (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 285200.0 €
- Université de Bielefeld (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 639400.0 €