Projet CHRONIC (Horizon 2020, appel à projets 2020)
Action : Doctoral Networks
Panel : Environment and Geosciences
Statut du projet : SIGNED

CHRONIC aims at delivering a cohort of highly-skilled and informed future research leaders trained in understanding and integrating, into risk-assessment practice, the long-term, low-dose chronic chemical exposure and their interactions with other environmental stressors. CHRONIC research will support improved decision-making in risk assessment based on uncertain and potentially conflicting information, and in the development of scientifically-based monitoring strategies. The focus on low chronic exposure to contaminants in different environmental organisms (macrophytes, invertebrates, vertebrates) and end-of-line systems (freshwater, sediment, soil) allow for a training that is broader than that achieved from conventional narrower one-system concept generally included in PhD-programmes and in standard protection goals. Thus, CHRONIC represents a paradigm shift in ERA methods and practices needed to deal with current and future contaminant challenges. CHRONIC will include 13 PhD projects aimed at developing tools and approaches to identify relevant nonstandard modes of toxicity for low chronic chemical exposure and integrate these with environmental stressors. CHRONIC includes academic institutions, research centres, government institutions, SMEs, and an NGO all with extensive experience in education and training and a high state-of-the-art scientific and technical expertise and infrastructure. The program will therefore lay the basis for an integrated approach to environmental risk assessment that includes non-standard yet ecologically relevant endpoints and low chronic exposure as key elements. CHRONIC include training-by-research, joint courses covering technical, scientific, ethical, and transferable skills. Students will also engage actively in communication to scientific and public communities and be enrolled in an ambitious intersectional networking exchange plan to increase employability and provide a broad perspective to their future career plan.

Mots clés : long term low contaminant exposure, non standard endpoints, behavioral, immuno modulation, genotoxicity, adverse output pathway  aop, transgenerational impact, epigenetics, environmental, stressors

Participants :
- Belgian Nuclear Research Centre (Belgique) — Partner, beneficiary, Recherche, subvention : 256320.0 €
- Université Marie et Louis Pasteur (France) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 274802.04 €
- Leiden University (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 265619.88 €
- Roskilde University (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 595044.0 €
- UK Centre for Ecology & Hydrology (Royaume-Uni) — Partner, beneficiary, Recherche, subvention : 606345.12 €
- Wageningen University & Research (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 531239.76 €
- Syngenta (Switzerland) (Suisse) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 281276.64 €
- Aarhus University (Danemark) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 297522.0 €
- Lund University (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 281982.96 €
- University of Aveiro (Portugal) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 237720.24 €