Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet NAPOLEON (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

NAPOLEON’s main objective is the development and demonstration of mapping ultra-broadband optical conductivity of novel conductive metal-organic frameworks (MOFs) by infrared nanospectroscopy (nano-FTIR). Conductive MOFs are critically important for the development of a highly efficient and low cost electrocatalysis for electric energy storage and retrieval. MOFs development needs the understanding of its conductive properties down to the nanoscale, which is not possible with traditional electrical transport measurements. Nano-FITR offers several advantages compared to traditional transport measurements: no contacts are needed, there are no problems with contact resistances, nanoscale materials can be measured, and the frequency-dependent response provides deeper insights into conduction properties than just DC measurements. However, current tabletop nano-FTIR systems are not able to characterise conductive MOFs due to the limited spectral coverage of the employed laser sources. To overcome this challenge I will introduce a novel plasma source-based nano-FTIR spectrometer, which will ensure the broadest spectral coverage. Then, I will develop a new model from which the anisotropic conductivity of MOFs can be extracted from nano-FTIR spectra. Finally, I will use the improved nano-FTIR system and the new model to study a highly conductive MOF sample, the CU-BHT, which demonstrated high electrocatalytic activity. NAPOLEON will provide innovative technologies, original methods and breakthrough knowledge in the fields of chemistry, nanooptics and solid-state physics. Specifically, NAPOLEON will develop the first methodology to measure optical conductivity in conductive MOFs with nanoscale resolution, which will contribute to boost the development of these materials. The results envisioned by NAPOLEON in terms of characterisation and understudying of new materials for electrocatalysis will be a key piece to achieve the EU target of carbon neutrality by 2050.

Mots clés : conductivity, s snom, nano ftir, conductive metal organic framework, infrared nanospectrosocy, infrared nanoimaging

Participants :
- Nanoscience Cooperative Research Center (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet ESTRELLA (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Through ESTRELLA I aim to develop energy efficient (i.e. field-driven), stable (retention time > 10 years), multilevel (16 state/4-bit) two-terminal devices based on 2D ferroelectric CuInP2S6 (CIPS). The project will provide a comprehensive investigation of CIPS material properties both as an exfoliated film and when integrated in ferroelectric tunnel junction (FTJ) devices through multilayer vdW epitaxy. The final devices aim to exploit the atomically sharp interfaces of vdW heterostructures, small domain wall energy and slow but stable switching of CIPS in order to produce a ferroelectric memory suitable for neuromorphic applications. Furthermore, I will investigate the impact of different electrodes on tunnelling electroresistance (TER) and switching voltages in order to design an optimal CIPS-based FTJ. This draws together my experience in the fields of ferroelectric devices and materials characterisation with that of the supervisor (Prof. Luis Hueso, CIC nanoGUNE), who is an expert on 2D materials and van der Waals (vdW) heterointegration. ESTRELLA will target areas of materials science - heterointegration techniques, 2D film characterisation; physics - understanding of domain dynamics and 2D material interfacial interactions; and electrical engineering - targeting FTJ devices as building blocks for neuromorphic computing. Parallel to my scientific work, with ESTRELLA I will develop skills as an independent researcher through publication and dissemination of my work, supervision, collaboration and project organisation.

Mots clés : ferroelectrics, 2d materials, van der waals heterostructures, neuromorphic, nanodevices

Participants :
- Nanoscience Cooperative Research Center (Espagne) — Coordinator, beneficiary, Recherche, subvention : 165312.96 €
Projet MIND-AD (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Alzheimer’s disease (AD) is the leading cause of dementia, affecting over 50 million people worldwide. Characterized by memory loss, cognitive decline, and the formation of amyloid-β plaques and neurofibrillary tangles, AD presents a significant global health burden. Current AD models, particularly in mice, fail to accurately represent the sporadic form of human AD, limiting the translation of research into effective treatments. Human-induced pluripotent stem cells (hiPSCs) offer a promising alternative for creating in vitro models, but these often lack key features of AD pathology and immune cell interactions. This project aims to develop a 3D organoid model for sporadic AD. We will use nanoparticles as nucleation seeds to facilitate amyloid aggregation from AD patient brain extracts, allowing a more faithful representation of AD pathology. By incorporating microglia into the model, we aim recapitulate human-specific microglial states in AD. By analyzing organoids with and without microglia, we will be able to investigate whether and how microglia contribute to initiation and progression of AD-related pathology, thus providing insights into this so far unanswered question in the field. We will compare all obtained readouts to idiopathic normal pressure hydrocephalus patient brain biopsies, that contain early AD-related pathology, thus verifying that our model is able to recapitulate features of human AD brain. This innovative approach will address the limitations of current models by integrating both neuronal and immune components, offering a more comprehensive platform for studying AD and testing potential therapies. Overall, the project has the potential to advance our understanding of AD mechanisms and contribute to the development of more effective treatments.

Mots clés : alzheimer s disease, microglia, cortical organoid, ipscs, proteomics, nanoparticle, amyloid beta

Participants :
- Université de l'est de la Finlande (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 242116.8 €
Projet VOCFire (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Boreal Forests are important emitters of biogenic volatile organic compounds (BVOCs), which have both warming and cooling effects on the Earth’s climate. These emissions are modulated by the frequency and severity of forest fires, which themselves increase due to climate warming. Forest fires drastically change ecophysiology of plants, that are responsible for the production of these gases. Yet, despite this significance, the effects of fire severity on BVOC emissions and the underlying plant metabolism remain poorly understood. In the EU-funded VOCFire project, I will address this knowledge gap by measuring post fire BVOC (particularly isoprenoids) emission from above- and below-ground in the boreal forest. Post-fire genetic level study of some BVOC-genes from Scots pine’s tissues will be explored. The VOCFire project will allow me to work in a world-leading group focused on the forest ecology and BVOCs fluxes. Together, we will bridge laboratory based experiments and field-based investigations through state-of-the-art metabolic networking to get a new understanding of emission of BVOCs, their specific functions and the gene expression associated with BVOC at three different level of forest fire severity, i.e., low, moderate and high. Reaching the project goal will require i) The quantification of above- and below-ground BVOC fluxes, and ii) the differential expression of BVOC producing genes of post-fire Scots pine.

Mots clés : biogenic volatile organic compounds, forest fire, boreal forest, tree, gene expression

Participants :
- CERCA Institution (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de l'est de la Finlande (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 242116.8 €
Projet SiLiS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

Rechargeable energy storage systems attract worldwide scientific and industrial interest due to their widespread applications. From the perspective of single customer, these batteries have been found useful in various portable devices and even in electric vehicles (EVs). Being practical in many circumstances, they have even more distinct role in reducing global warming and the emission of greenhouse gases. Together with the limited sources of fossil fuels, these aspects have driven the efforts to utilize more green sources of energy like wind and solar power, aiming at sustainable energy production. One critical factor on the way to zero-carbon footprint is to change the transportation to function solely with green electricity. The current EV industry depends heavily on lithium-ion batteries which face technological challenges like limited storage capacity and safety concerns related to the use of liquid electrolytes. Further, these batteries utilize materials that are far from being sustainable and environment friendly. To address these issues, the proposed SiLiS project will focus to develop new battery technology employing high-capacity silicon anode, lithium sulfide-based cathode, and stable and safe polymer based solid electrolyte. The project will support the development of cost-effective batteries to reduce greenhouse gas emissions from transportation by means of electric vehicles. The proposed all-solid-state silicon-sulfur cells (SSCs) is expected to have the gravimetric energy density of 750 Wh/kg, power density of 1500 W/kg and volumetric energy density of 1300 Wh/L. The novel high energy density battery will be of low cost, with a prolonged cycle life which is better than the current Li-ion battery. Thus, SiLiS will develop next generation rechargeable batteries by employing novel material synthesis routes and cell design that enable EVs to have long driving range with minimum safety concerns at a lower cost.

Mots clés : energy storage, li ion battery, silicon anode, lithium sulfide cathode, solid polymer electrolyte, high energy density and power density, long cycle life, low cost rechargeable battery

Participants :
- Université d'Uppsala (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de l'est de la Finlande (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 215534.4 €
Projet CARE-KNEEOA (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Knee osteoarthritis (KOA) is a leading cause of disability worldwide, with ~14% prevalence in Europeans aged over 40. KOA prevalence continues to rise, thus far, with no cure or proven prevention protocols. Nonetheless, an aberrant knee mechanobiological environment is known to accelerate KOA development. Tailored rehabilitation, aiming to favorably alter knee biomechanics and restore the joint, has shown great potential to postpone or decelerate KOA progression. But current rehabilitation protocols are based on indirect measures of knee biomechanics, often leading to suboptimal outcomes. Computational models have offered great potential for simulating knee mechanical response in functional activities, though none are developed in a holistic and individualized context. More importantly, they lack the prediction capability of tissue degeneration/regeneration to loading and the potential for clinical use, i.e., are not automated and fast and cannot use out-of-lab motion data. In this project, I will develop and validate highly personalized in silico tools to quantify knee cartilage mechanobiological degenerative/regenerative response geared towards out-of-lab and clinical use for predicting KOA progression in different functional activities, allowing personalized rehabilitation. The multiphysics computational models, assisted with artificial intelligence (AI), will be validated at different spatial scales using in vitro tissue and cell level experiments and in vivo joint loading and quantitative medical images. This multidisciplinary project bridges together complementary skill sets of Dr. Esrafilian, Profs. Korhonen’s and Delp’s teams, with their expertise in biomechanics, computational modeling, biochemistry, biology, and AI. The beyond state-of-the-art models of this research can make a profound impact on early-stage KOA prediction and treatment planning, potentially increasing the quality of life in KOA individuals and reducing the need for surgical interventions.

Mots clés : articular cartilage, knee osteoarthritis, finite element modeling, neuromusculoskeletal modeling, artificial intelligence, image processing, mechanobiology, predictive model

Participants :
- Université Stanford (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de l'est de la Finlande (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 302331.36 €
Projet FAQ-QuantuM2D (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Understanding the dynamics of quantum matter far from equilibrium is both challenging and has crucial implications for various fields, including statistical mechanics, condensed matter, high-energy physics, and quantum information theory. The difficulty arises from the prohibitive cost of classical simulations and the limited availability of analytical tools. This understanding is not only fundamental for quantum phenomena but also essential for advancing cutting-edge quantum computing technologies, a key global priority identified in the Horizon Europe Work Programme. While recent progress has been made in understanding one-dimensional interacting systems, the dynamics of quantum systems in two dimensions remain poorly understood. Strong indicators, such as the emergence of anyons, suggest that dynamics in two dimensions can be fundamentally different. This project, FAQ-QuantuM2D: Far-Away-from-eQuilibrium QANTUm Matter in 2 Dimensions, aims to advance the state of the art by leveraging a combination of analytical and numerical approaches. The project focuses on local quantum circuits, which are minimal models for many-body quantum dynamics that have led to groundbreaking analytical insights in recent years. Moreover, they are native to quantum computing applications. The proposal will advance our understanding of far-from-equilibrium dynamics and emerging dynamical phases of quantum matter through three specific scientific objectives: understanding localized and ergodic dynamical phases in 2D kinetically constrained models, understanding 2D strongly localized phases, and uncovering novel non-equilibrium dynamics unique to 2D systems. FAQ-QuantuM2D will deepen our understanding of quantum dynamics, yielding significant insights for fields focused on quantum dynamics and quantum technologies. Concretely for the latter, the results can be used for benchmarking quantum computers and finding suitable, classically hard, tasks for them.

Mots clés : dynamics of quantum matter, nonequilibrium statical mechanics, quantum many body physics, exact solutions, quantum circuits, localization, quantum spin models, universal features of many body dynamics

Participants :
- Université de Ljubljana (Slovénie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 198557.52 €
Projet Stacky Manin (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : SIGNED

Abstract: Manin’s conjecture is a famous conjecture in arithmetic geometry, predicting asymptotically the number of rational points of bounded height on Fano varieties. In a breaking recent advance, the researcher and Yasuda have [Darda-Yasuda]extended it to stacks, which explains Malle’s conjecture on the number of Galois extensions with fixed Galois group of bounded discriminant. The leading constant in the asymptotic formula, however, remains unknown. A reason for this is that we still have very little verified examples of Stacky Manin’s conjecture. In this proposal, we identify a class of stacks for which the conjecture seems to be approachable, namely, the class of smooth complete intersections in weighted projective stacks which enjoys rich geometric properties. We then plan to analyze the obtained constant, compare it with existing examples, to guess the shape in the general case.

Mots clés : manin s conjecture, malle s conjecture, rational points, peyre s constant

Participants :
- Université Sabancı (Turquie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148478.4 €
Projet BIOSOCIOPOLIS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

This project will develop a new interpretive model to reveal the extent to which multiple socio-political transitions, representing different forms of urbanism, affect human lifeways and deathways, in a diachronic perspective. This is achieved by implementing an interdisciplinary methodology combining archaeological and historical theory, macroscopic bioarchaeological approaches and stable isotopes. The diachronic case of Amphipolis in Northern Greece experiencing many different political models between the Late Archaic/Classical and Roman periods is an ideal case study. Human skeletal remains from 300 inhumation and 100 cremation burials, spanning between the 5th c. B.C. to 1st c. A.D. will be analyzed. Methods will include: 1) studying funerary practices and deathways, 2) investigating health and lifestyle and 3) exploring biodistance and human mobility. I will also initiate an open access collaborative morphological biodistance database to create long term impacts on human mobility studies. By moving to AUTh, I will work closely with Sevi Triantaphyllou, a top-leader in funerary practices and osteoarchaeology. Her expertise, along with resources and specialties of other distinguished staff members of School of History and Archeology provide the perfect environment for the multi-dimensional contextual training, necessary for the project and for my career metamorphosis. A period of secondment is included at BB-LAB (VUB), with Christophe Snoeck, an expert on isotopic geochemistry and a global pioneer on the topic of isotopic study of cremated human remains. My career goal is to be a research leader in Social Bioarchaeology, which this project will enable by developing an integrated method for the combined analysis of mortuary environment with lived experience. Through a multi-faceted training in core skills, along with supervision, teaching and public outreach, I will develop key resources to maximize the impact of my career advancement.

Mots clés : social bioarchaeology, socio political bioarchaeology, lifeways, deathways, funerary practices, health and lifestyle, mobility, biodistance, ancient greek world, classical world

Participants :
- Vrije Universiteit Brussel (Belgique) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Aristote de Thessalonique (Grèce) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 153486.72 €
Projet CRIME (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Interconnects impose major limits on the performance on integrated circuits during the exponential reduction of feature size of microchips. The semiconductor industry faces challenges in the metallization of interconnects below the 10 nm half pitch and is looking to alternative metallization schemes to replace copper, the traditional choice for the last 20 years, which no longer meet the conductivity requirements at decreasing length scales. Binary metals such as nickel-aluminium (NiAl) have been identified as a promising candidate that performs well with respect to resistivity at critical dimensions (sub-10 nm) to replace copper. However, there are several challenges associated with the instability of these materials regarding surface oxidation, leading to performance degradation. The objective of CRIME is the in-situ removal of the surface oxide and in-situ passivation of binary intermetallic compounds to prevent surface oxidation at the sub-10 nm half pitch for interconnect applications. To meet the future size requirements of interconnects, the downscaling of the cleaning and passivation processes from blankets to sub-10 nm half-pitch and the formation of patterned lines, with the aim of sub-7 nm half-pitch, will be performed. This will be achieved through an interdisciplinary approach that combines material science, chemistry, chemical engineering, nanoelectronics, and physics, to test different metal oxide removal and surface cleaning chemistries in combination with organic and inorganic passivation layers in-situ to overcome the formation of an oxide top layer. The passivation layers will be deposited in the liquid and vapour phase and various analytic techniques will be used to elucidate the surface chemistry and surface reaction mechanisms. CRIME goes beyond the state-of-the-art as the cleaning and passivating process and the downscaling of these processes on NiAl at the nanoscale and for advanced microelectronics nodes has not been previously demonstrated

Mots clés : interconnects, intermetallic films, passivating layers, metallisation, binary metals, patterning, vapour phase deposition, liquid phase deposition, back end of line beol , nanopatterning

Participants :
- Institut de micro-électronique et composants (Belgique) — Coordinator, beneficiary, Recherche, subvention : 191760.0 €