Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet NeuroVascOme (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The prenatal and early postnatal life are particularly vulnerable phases for brain development, during which essential neurodevelopmental processes occur. One such vital process is the development of the neurovascular unit resulting in the formation of blood brain barrier (BBB), which is the gateway regulating access of the external milieu to the brain. Concomitant with the postnatal BBB development, the maturation of our resident gut microbiota also occurs during this sensitive period of early life. Altered gut microbial composition has been shown to affect BBB function and is increasingly being linked to adverse health outcomes including neurodevelopmental disorders, such as autism or attention deficit hyperactivity disorder. However, an exact mechanistic understanding of how this early life alteration in microbiota composition leads to brain dysfunction is not known. The NeuroVascOme project aims to investigate the link between early life microbiota perturbations and neurovascular development, which in turn is crucial for brain homeostasis. And more precisely, how are the different disruptors of microbiome in early life impacting the neurovascular/BBB integrity, thereby predisposing the organism to health deficits in later life. This is especially relevant for our modern-day society wherein early life microbiome disruptions caused by increased stress, antibiotic administration and caesarean delivery methods are widely prevalent. In accordance with the aims of the MSCA fellowships, NeuroVascOme project will greatly aid my career development by providing first rate training in academic and industry settings that will enhance my research skillset, foster my managerial abilities and strengthen my professional network. Additionally, public, industry, and scientific audiences will be informed about the outcomes of the project through a dissemination strategy that will aim to promote the role of early life environment in shaping mental health.

Mots clés : brain gut microbiota axis, microbiome, neurovascular development, blood brain barrier, neurodevelopmental disorders, early life, neurovascular unit

Participants :
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 196590.72 €
Projet MIGMIPS (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The presence of micro and nanoplastics is now documented in the drinking water, ocean, marine invertebrates and fishes. Their toxicity for humans is still mostly unknown, as well as their capacity to translocate through the gut barrier, especially since it depends strongly on the size, shape, surface state, material of these plastics, which are strongly heterogeneous or even contaminated by organic or toxic compounds. In this project, I propose to develop new in-vitro systems in order to quantify the translocation of environmental nano and microplastics obtained from plastic wastes, through the gut epithelial barrier. This proposal includes the development of 1- microphysiological systems mimicking that barrier and 2- detection techniques for the characterization of micro and nanoplastics directly inside biological tissues (Raman-SERS, SEM, AFM, confocal microscopy) or in liquids.

Mots clés : microfluidic, organ on chip, microplastic

Participants :
- Centre national de la recherche scientifique (France) — Coordinator, beneficiary, Recherche, subvention : 184707.84 €
Projet SafeFood (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

The presence of undeclared allergens in food products poses a serious health risk to consumers and results in important economic losses for the food industry. The detection of allergens is typically performed using immunological methods. DNA-based methods complement immunoassays and provide higher specificity and sensitivity, especially in processed foods. DNA-based identification of allergens can currently only be performed using well equipped laboratories which can be difficult to implement in an industry settings where the identification should be fast and on-site. In SafeFood, I will develop a protocol to implement cutting-edge Nanopore sequencing technology for rapid, portable identification of allergenic plant ingredients in complex, multi-ingredient food products. DNA-based identification of allergenic plant species has been challenging due to the lack of variation of the traditional DNA barcodes. I will implement more robust species identification methods based on whole plastid genomes. First, I will compile a comprehensive open-access database of allergen species’ plastomes. Then, DNA extraction and library preparation will be optimized for an on-site protocol tailored to the constraints of the food industry. I will create artificial mixtures of complex food, with varying concentrations of allergens to test the method’s sensitivity, specificity and repeatability and compare the results to those of immunoassays. This innovative solution will solve an industry challenge by allowing on-site, fast and accurate allergen identification. By being hosted at a leading DNA service company, BaseClear, and with the collaboration of a specialised academic partner in EU food safety analyses, RIKILT, I will apply my expertise in plant genomics, develop skills in food chain analyses, in R&D and entrepreneurship. At the completion of this fellowship, I will be able to apply this knowledge and skill to further address societal challenges in the food industry.

Mots clés : nanopore technology, allergens, genomic barcoding

Participants :
- Modul-bio (Pays-Bas) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 187572.48 €
Projet VolatileOrigin (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : TERMINATED

The presence of volatile elements such as carbon, nitrogen, water, noble gases, on terrestrial planets is a requirement for planet habitability, yet their origin is still highly debated. Noble gases are invaluable tracers of volatile sources due to their inertness, in particular their non-radiogenic isotopes have kept remnant signatures of planetary accretion. Krypton and xenon are mighty tools to distinguish between chondritic and solar volatile sources due to the distinct isotopic compositions of these end-members. However, the heavy noble gas (Kr, Xe) compositions of the Earth’s mantle is poorly determined. Hence, the Earth’s mantle volatile history remains largely unknown. The objectives of this project are to precisely measure the non-radiogenic Kr and Xe isotopes in mantle-derived samples, including mid-ocean ridge basalts and diamonds, and in meteorites of different types in order to better understand Earth’s volatile origin. Determining the compositions of mid-ocean ridge and diamond samples will allow to characterize the extent of mantle Kr and Xe heterogeneities, introduced through progressive atmospheric noble gas recycling via subduction, and, hence to identify the source(s) of these volatiles in the mantle. Precise bulk meteorite data for the non-radiogenic Kr and Xe isotopes are incomplete and will be crucial in our understanding of the measured mantle compositions to fingerprint the volatile sources. This project will use a novel protocol for the specific measurements of these isotopes in mantle-derived samples associated with noble gas mass spectrometry. The MSCA fellowship represents a unique opportunity for me to learn new analytical skills in cosmochemistry, to improve my soft skills and to secure my fruitful reintegration in Europe. I will transfer to the host lab my expertise of mantle geochemistry. On the whole, this project will strengthen my scientific independence, taking me closer to achieve an outstanding academic position in Europe.

Mots clés : noble gases, origin of volatiles, earth s mantle, meteorites, krypton, xenon, noble gas mass spectrometry

Participants :
- Board of the Swiss Federal Institutes of Technology (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 203149.44 €
Projet SLUW (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The present project aims at analysing the morpho-syntactical features of the Luwian language working on the available texts and combining a standard linguistic analysis with the implementation of a statistical analysis of the annotated corpus. By glossing the morpho-syntactical structure of a large selection of both cuneiform and hieroglyphic inscriptions using a protocol derived from and compatible with the Penn Treebank Project and the Leiden Glossing Rules, the research will proceed by isolating, mapping and modelling the regular as well as the anomalous features of the morpho-syntax of one of the most important and still largely unexplored languages of the ancient Anatolian branch of Indo-European. The analysis will also identify and focus on the co-dependant syntactical, morphological, semantic and stylistic phenomena present in the corpus (e.g. syntactic triggering of stylistic features, dislocations, topicalisations). The results of the present research will provide the world of the Indo-European studies with the first comprehensive study ever dedicated to morpho-syntax of the Luwian language.

Mots clés : luwian, anatolian, indo european, syntax

Participants :
- University of Verona (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 180277.2 €
Projet PhthaloSupra (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The present project aims at realizing a significant step forward in the use of noncovalent interactions as a “tool” to self-assemble phthalocyanines (Pc), planar and aromatic macrocycles which possess several unique physicochemical properties such as an intense absorption in the red/near-infrared region of the solar spectrum, a rich redox chemistry, and a tuneable bandgap. In PhthaloSupra, the fellow will prepare stable Pc-based supramolecular polymers self-assembled though the combination of pi-stacking, and hydrogen or halogen bonding interactions, noncovalent interactions which have never been used “simultaneously” to self-assemble in a controlled fashion Pc derivatives into supramolecular polymers. For such ensembles, he will study some fundamental properties such as their self-assembly mechanism, light-harvesting capability, and helical chirality, all aspects that are raising nowadays a great deal of scientific attention. The photovoltaic properties of some of the prepared architectures will also be investigated contributing to address the European and international growing interest towards reducing energy consumption through the realization of smart materials for low-cost optoelectronic technologies. Diffusion of the PhthaloSupra achievements will be given not only to specialized researchers, but also, an importantly, to the general public in the form of several outreach activities. Undoubtedly, the opportunity for the candidate to work in a group of the highest scientific quality such as the one of Prof. Torres, and in a highly multidisciplinary and challenging project such as PhthaloSupra will strengthen his potential to mature further to an independent, highly trained researcher. Moreover, he will develop transferable skills, such as research management and organization, competencies which will help him to function more effectively in multidisciplinary and multicultural environments, thus improving his career perspectives.

Mots clés : phthalocyanine, self assembly, supramolecular interactions, hydrogen bonding, halogen bonding, pi stacking, donor acceptor ensembles, photovoltaics, supramolecular polymers, chirality

Participants :
- Autonomous University of Madrid (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 170121.6 €
Projet Young-Italian 2015 (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The present project aims to examine Italian cinema during the twenty-year period from 1943 to 1963 in relation to the construction of the image of the young Italian man. The main goals are to understand how Italian cinema from the post-war period to the ‘economic boom’ gave substance to male national identities and to situate those identities within an emerging youth culture produced by the new consumer society in Italy. The proposal arises from two key observations: firstly, that the cinematic institution of the time and its gender representations depicted the crisis of traditional male authority at a time of great social change. In this respect, the figure of the young Italian man functions as a multi-faceted trope that challenges the patriarchal values embodied by older men. Secondly, that there has been a lack of studies of Italian cinematic masculinity, especially in the postwar period. From this perspective, the project intends to complement existing work in the fields of history and sociology on the emergence of Italian youth culture; it will uncover the repertoire of young masculine identities that cinema offered to audiences in these years, which were crucial to the negotiation of changing gender roles in the Italian cultural imaginary after the WWII until the present. The project is organised according to an integrated and interdisciplinary approach to the cinematic apparatus. The purpose is to look at the cinematic institution by analysing its textual and economic dimension (its ‘material’ component), and thus investigating the patterns of masculine representation offered by films and the related cultural industry; and by evaluating its cultural and social articulation (its ‘symbolic’ component), and thus focusing on the cinema audiences and their experiences with the film texts in relation to gender identity. The principal output will be a monograph on the figure of the young Italian man in the cinema of the long post-war period, the first of its kind.

Mots clés : italian cinema, gender, masculinity, national identity, youth

Participants :
- University of Bristol (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet MAGTOPRECON (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The present project aims to explore and control the behavior of magnetic topological defects in weak Perpendicular Magnetic Anisotropy materials by creating different hard/soft magnetic nanostructures with reconfigurable properties.Both, static and dynamic behaviors will be exploded and finally, a demonstration device will be prepared: a reconfigurable magnonic crystal with potential applications in information and communication technologies.Weak perpendicular magnetic anisotropy materials present fascinating magnetic stripe domain arrangements sharing phenomenology with other self-organized systems.These magnetization configurations can be understood as a 2D magnetic crystal.Topological defects within the stripes’ lattice condition and drive the magnetization processes of the system being their study a key factor for both, fundamental and technological goals. One of the objectives of the project is to go a step further in the study of magnetic topological defects in these systems. We want to characterize, with unprecedented detail, the behavior of magnetization textures and control their evolution by locally tuning the film properties.Not only static properties will be analyzed, but also the dynamics. It will allow to observe interesting spin wave phenomena, and ultimately, to identify and excite the dynamic modes of topological defects.To achieve this, a unique combination of ferromagnetic resonance with Lorentz Transmission Electron Microscopy will be used, with guidance from micromagnetic simulations. On the other hand, the aforementioned system can be used as key element in the development of low energy consumption reconfigurable magnetic devices. We want to demonstrate it by creating a reconfigurable magnonic crystal combining patterned soft magnets and weak perpendicular magnetic anisotropy elements. The work will mainly be conducted at the University of Glasgow, with some fabrication performed at University of Oviedo in Spain, over a period of 2 years.

Mots clés : weak perpendicular magnetic anisotropy, magnetic topological defects, lorentz microscopy, magnetization dynamics, spin waves, reconfigurable magnetic devices

Participants :
- University of Glasgow (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet PETITE GUERRE (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The present study aims to investigate the Algerian War of Independence (1954–62) from a new perspective. It proposes to frame a transnational history of the war, going beyond both the (opposing) French and Algerian (national) narratives, to resituate the war in its Mediterranean, European, and eventually its global contexts. This general research objective, however, will be achieved by using a microhistorical approach: instead of looking at the conflict as a generic “whole” and examining its reverberations in an elusive “collective memory”, the project focuses on a specific region, the Aurès-Nememcha in the Algerian south-east. At the core of this project are the specific experiences and memories of French and Algerian veterans who fought each other for eight years, in this mountainous, Berberophone area. Who were they? What kind of war were they fighting, and why? And fifty years after the ceasefire, how do the citizens of each country cope with their combat memories? The project will mobilise a wide range of sources, mostly but not exclusively French and Algerian. Aiming to analyse both past events and their present memories, this study will rely on both qualitative and quantitative analytical methods, in a truly interdisciplinary framework. Indeed, this “global microhistory” approach—beyond being an original contribution to historical research—aims to offer new knowledge of and insights into the Franco-Algerian War, in order to help the two countries to go beyond the narrow national narratives that continue to fuel an unexhausted “memory war” that is ongoing both between and within Algeria and France. If the efforts of the EU and the Union for the Mediterranean (2008) may help to set a new tone in the near future, today it is less at the state level that it is possible to act than at the level of the people, by focusing on their particular and familial stories.

Mots clés : algeria, france, history 20 21th century, algeria war for independence, decolonization, mediterranean, conflicts studies, memory studies, veterans

Participants :
- University of Oxford (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet TEMPOMATH (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : CLOSED

The primary aim of the action is the construction and analysis of new predictive and verifiable mathematical models that can uncover the effects of time delays upon various cell biology processes. In this timely project we aim to apply cutting edge functional differential equation techniques to interrogate a number of cell biology processes of huge current interest, including collective cell movement, tumour growth and self-organizing pattern formation. The ultimate goal of this research is to develop new mathematical ways to understand and control cell biology processes. The successful outcome of this project will be robust and experimentally testable mathematical theories that can be applied to a wide variety of biological and medical problems, whenever temporal delays are relevant. The researcher will be intensively trained in areas of mathematical biology that are new to him, by exploring a range of cell biology processes that are the focus of current state-of-the-art research efforts within the Oxford mathematical biology group, and investigate the role of delayed feedbacks and memory effects in these processes. These mathematical models will share common mathematical themes and challenges. Thus while being exposed to these fundamental areas of mathematical biology (cell motility, tumour growth, wound healing, pattern formation, development etc.), we aim, simultaneously, to develop new mathematical tools that have a wide range of important and timely biological applications. The researcher will be fully integrated into the Wolfson Centre for Mathematical Biology at the Mathematical Institute of the University of Oxford. The project will allow him to significantly broaden his area of expertise and initiate new long term collaborations.

Mots clés : time delays, differential equations, nonlinear dynamics, mathematical biology, mathematical modeling

Participants :
- University of Oxford (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 146591.1 €
Projet NEWMAN (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

The primary goal of the NEWMAN project is to train a talented researcher with a strong academic background in fibre-optic communication, through a research programme focused on developing next generation wavelength-division-multiplexing (WDM) technologies, and their usage as a for metro and access optical communication networks. The aimed WDM technologies supporting low-cost low energy consumption are highly desirable, since the number of metro and access links are forecasted to be massive in the next generation networks and will contribute to major portion of total energy consumption of the global network. The success of this project will contribute knowledge to the fields of laser science and fibre-optic technology, and establish an internationally leading position for Europe in the industrial applications relevant to fibre-optic networks. The Fellow, Dr. Xiaodan Pang, will receive substantial training activities in professional knowledge and skills in the field of WDM systems. In turn, Dr. Pang will also bring his academic frontline research expertise to the industrial development of the field of fiber-optic communication. This will take place at the EU non-academic host (Infinera Metro Business Group R&D HW), and academic secondments to the KTH Royal Institute of Technology and ACREO Swedish ICT. This training-through-research project will significantly enhance the Dr. Pang's competence in both academic and applied research areas, establishing him as a leading figure in optical communication research and industry communities that are strongly linked to the European universities and industry. Therefore, the NEWMAN project shows a strong coherence with the Society & Enterprise Panel (EF-SE) of the Marie-Curie Individual Fellowships, which is dedicated to career opportunities for researchers seeking to work on research and innovation projects in non-academic organization.

Mots clés : fibre optic communications, wavelength division multiplexing, coherent optical communication advanced modulation formats, digital signal processing

Participants :
- Transmode systems ab (Suède) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 185857.2 €