Projet SynCrop (Horizon 2020, appel à projets 2017)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : CLOSED

The repertoire of industrially produced fine chemicals in various biological systems will rapidly expand using the tools from the emerging field of synthetic biology. However, the high-level production of non-natural products or de novo activities through synthetic circuits compromises the integrity of host organisms, which significantly impacts or even prevents the development of an industrial pipeline. Our ability to exploit the potential of synthetic biology for industrial production is constrained by our understanding of the integrated cell response when introducing a new synthetic circuit into the homeostatic network of the cell. SynCrop’s main goal is to establish a European Training Network that merges the fragmented scientific expertise in theoretical, experimental and application-driven quantitative biology to educate the next generation of researchers to construct modular and tunable synthetic circuits and foster the development of novel production platforms for food additives (e.g. vitamins, carotenoids and exopolysaccharides). Researchers with inter-disciplinary skills in both experimental and computational biology are needed to solve complex application-driven problems. SynCrop brings together ten academic partners from quantitative biology, cell engineering, microbial physiology and mathematical modelling fields and six industrial partners, including key experts in metabolic engineering and industrial biotechnology. The consortium will provide 15 early-stage researchers with cutting-edge multi-disciplinary research training, through tailored research projects, rigorous exchange of expertise among researchers and partners, and participation in specialised courses, workshops and conferences augmented by extensive training in complementary skills. SynCrop will generate a strong cohort of highly-employable scientists with unique inter-disciplinary and intersectoral skills to address complex questions and develop innovative biotechnological processes.

Mots clés : quantitative biology, quantitative single cell biology, biophysics, biological chemistry, cell engineering, microbial physiology

Participants :
- Insilico Biotechnology (Germany) (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Chr. Hansen (Denmark) (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 290081.88 €
- biosyntia aps (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 290081.88 €
- Technische Universität Berlin (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 249216.48 €
- University of Aberdeen (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 273287.88 €
- University of York (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 273287.88 €
- Universität Hamburg (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 498432.96 €
- Biofaction (Austria) (Autriche) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Board of the Swiss Federal Institutes of Technology (Suisse) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 265226.76 €
- University of Groningen (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 510748.56 €
- Lanthiopep bv (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Chalmers University of Technology (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 263659.32 €
- Vrije Universiteit Amsterdam (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 255374.28 €
- DSM (Netherlands) (Pays-Bas) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 255374.28 €
- University of Edinburgh (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 546575.76 €
- University of Bristol (Royaume-Uni) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €