Projet STACCATO (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks - Industrial Doctorates
Panel : Life Sciences
Statut du projet : SIGNED

Our ability to utilise biological systems to produce medicines has improved the quality of life for millions of EU citizens. In recent years a new wave of exciting biopharmaceuticals have been discovered with the potential to advance current treatments for a variety of disorders. These new medicines, however, are becoming increasingly complex and difficult to manufacture. Overcoming the inherent heterogeneity of cells grown in vitro to produce effective, uniform and safe biopharmaceuticals is one of the most significant challenges faced by industry today. The STACCATO European Industrial Doctorate has been specifically designed to strengthen Europe’s innovation capacity and leadership in the BioPharma sector. The consortium will provide exceptional intersectoral training to 11 ESRs through pioneering research focused on harnessing recent advances in single cell analysis to generate and apply a new suite of tools for cell culture process development. ESRs will participate in a specialised training programme to build their proficiency in essential research and industry disciplines. Additional training in professional skills and entrepreneurship will enable ESRs to become future leaders in biopharmaceutical manufacturing science. STACCATO is composed of an industry leader in instrumentation for cellular analysis, 3 innovative biotechnology SMEs, a leading academic institution and a research conducting biological medicines regulatory agency. The STACCATO EID will immerse all ESRs in highly dynamic industrial environments while receiving supervision from leading academics. A feature of STACCATO is collaboration amongst experts in the production of different biopharmaceuticals such as therapeutic proteins and CAR T cell therapy. All ESRs will receive unparalleled exposure to pan-biopharmaceutical manufacturing challenges to foster collaboration, catalyse synergies across the network and ultimately create a truly unique training experience.

Mots clés : biopharmaceutical manufacturing, bioprocess development, single cell analysis, gene therapy, cell therapy, therapeutic protein, vaccine, oncolytic virus, next generation sequencing, mass spectrometry

Participants :
- Instituto de Biologia Experimental Tecnológica (Portugal) — Partner, beneficiary, Recherche, subvention : 475440.48 €
- National University of Ireland (Irlande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- National University of Ireland (Irlande) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- KTH Royal Institute of Technology (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 563965.92 €
- Meiragtx uk ii ltd (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Paul Ehrlich Institut (Allemagne) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 505576.8 €
- National Institute for Bioprocessing Research and Training (Irlande) — Coordinator, beneficiary, Recherche, subvention : 824052.96 €
- Northx biologics matfors ab (Suède) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Spiber Technologies (Sweden) (Suède) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Universidade Nova de Lisboa (Portugal) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Helsinki (Finlande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Accelopment (Switzerland) (Suisse) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Tilt biotherapeutics oy (Finlande) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 280805.76 €
- Horizon Discovery Group (United Kingdom) (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Becton Dickinson (United States) (Irlande) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 274684.32 €
- Technical University of Darmstadt (Allemagne) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €