Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet Hi-NEAT (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

The proposed research seeks to advance the state of the art in skin cancer diagnostics by developing an electrochemical sensor for tumour markers (or biomarkers) utilizing hierarchical nanoengineered assemblies of titania (Hi-NEAT) nanoparticles. Melanoma is the most aggressive and deadliest form of skin cancer that can spread quickly to other body areas, so its early identification and treatment are vital. The existing histological and immunological cancer detection techniques are intricate, expensive, and often lack sensitivity and specificity. Therefore, in this project, we intend to introduce a subtle, rapid, accurate, facile, and low-cost Hi-NEAT-based electrochemical sensor to detect the biomarker tyrosinase, a crucial enzyme involved in melanin overproduction and development of skin melanoma. The following two research goals have been set forth to achieve this: 1) Creation of Hi-NEAT nanoparticles with enhanced electrocatalytic activity towards tyrosinase via tuning their physicochemical/surface properties and 2) Employing large-scale facilities (synchrotron/neutron sources) to investigate the interfacial properties of the titania-tyrosinase interaction. Thus, the current project represents a groundbreaking approach to push the frontiers of skin cancer diagnosis through the innovative use of titania nanoparticles and large-scale facilities for developing an effective point-of-care electrochemical sensor. Success in this research promises heightened precision and sensitivity in melanoma detection, potentially leading to timely diagnoses and improved patient outcomes. Ultimately, we aspire to make a significant contribution to health care by lessening the severity of melanoma, reducing overall care expenses, and increasing the lifespan of cancer survivors in line with the European Commission’s beating cancer plan.

Mots clés : melanoma skin cancer, early diagnosis, electrochemical sensors, titania nanoparticles

Participants :
- Université de Malmö (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 222727.68 €
Projet ORa.CL.E (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The ORa.CL.E project aims to shed light on overlooked producers of knowledge about society – specialised Catholic Action (CA) – and explore the hypothesis of the circulation of religious militant-based knowledge to academic sociology. Social classifications were the essence of the project of the so-called “specialised” CA movements, which proposed selective pastoral approaches according to ‘life milieus’. This segmentation was not simply a strategy imposed by the episcopates ‘from above’, but was a continuous process of differentiation and identification by class and by gender at all levels. Assuming that CA specific forms of organisation produced social categories and knowledge that might have circulated to the field of academic sociology, ORa.CL.E offers an innovative reinterpretation of the history of specialised Catholic Action, from a sociology of science perspective. The project transcends the traditional monographic historical studies of CA, by developing an original comparative methodology based on the analysis of five understudied CA movements for adults from rural and independent backgrounds in France and Belgium from 1931 to 1986. ORa.CL.E provides new insight on the role of religion in social distinction and offers new perspective on the relationship between science, religion and civil society. Such a renewal is essential in the current European context, where experts and the media often present religious experience as an individual phenomenon, autonomous from social structures. In consultation with actors from present-day CA education movements, the project will provide tools to better understand the circulations between religious “ground” knowledge and “academic” knowledge, which will help in the future to make better use of the former and improve the social relevance of the latter.

Mots clés : catholicism social movements laity social classes sociology of science history of sociology rurality xxth century

Participants :
- Fondation nationale des sciences politiques (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 226420.56 €
Projet MATRIx (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The MATRIx aims to develop a 3D melanoma tumor model on a chip (ToC) using patient-derived xenograft technology, which mimics the natural tumor microenvironment (TME) to enhance nanoparticle (NP) delivery to the tumor site and enable personalized treatment. In Western countries, melanoma is considered one of the most widespread cancers. Due to its aggressive nature and resistance to drugs, melanoma is the subject of extensive research aimed at creating more effective medications. The clinical translation of nanomedicine for cancer therapy has been hindered by a lack of knowledge regarding the TME, mechanisms of NP uptake and transfer, technical limitations for model implementation, and individual variations in phenotype. ToC modeling is an indispensable tool in cancer research providing a 3D dynamic environment with regulated fluid flow and shear stress, co-culturing, vascularization, easy operation and readout method, and time and cost saving in contrast to other cancer models. in addition, ToC provides high-throughput screening of nanomedicines, susceptibility, and resistance of cancer cells against drugs, allowing personalized therapy for patients with low cost and high reproducibility. Development of NPs based on patient’s melanoma TME response to active targeting NPs is the focus of MATRIx which will be implemented for the first time. My project's key deliverables will consist of identifying key players of TME around NP extravasation and enhancing NP retention at the tumor site. This initiative will aid in the development of more effective personalized cancer treatment strategies and will be of considerable interest to both academic and industrial sectors. MATRIx also fills my knowledge gaps. Following MATRIX conclusion, I will establish myself as a leader in the field of NP development, alongside tumor modeling on chip technology. I will receive advanced training skills to equip myself for conducting independent research and securing a permanent academic role.

Mots clés : 3d melanoma tumor model, tumor on chip toc , personalized nanomedicine, patient derived xenograft pdx , nanoparticles transfer on tumor, targeted np on melanomatoc, in vitro tumor modeling

Participants :
- École polytechnique de Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 235668.69 €
- Biomimx srl (Italie) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet STRIPES (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

The evolutionary history of the genus Equus is a paradigmatic case of adaptation to different environments through time. Modern equids may be divided in two large groups based on genomic and morphologic evidence: the caballine horses (Przewalski’s and domesticated horses) and the stenonian wild equids (zebras and asses). Although molecular studies have clarified the evolutionary history of the caballine horses, the origin and evolution of the wild zebras and asses remains enigmatic, despite their well deciphered genomes. STRIPES aims to resolve the phylogeny of the genus Equus, with emphasis on extant zebras as well as African and Asian asses. To do so, I plan to study the fossil horses collections housed at the ICP (Sabadell, Spain), of the the MNHN (Paris, France) and of the NHMUK (London, England). These institutions have important collections from key sites in Eurasia and Africa, with ages matching with the estimated divergence time interval between zebras and asses at ca. 1.8 Ma. I will use 2D and 3D geometric morphometric approaches to more accurately characterize the anatomy of the fossil and living Equus species, and I will further integrate morphological information with genomic (paleoproteomic and molecular) data to perform the first Bayesian total evidence (tip dating) phylogenetic analysis of the genus Equus, which will enable to refine the branching topology and estimated divergence dates of its main lineages. The combination of paleontological and neontologial data, both morphological and molecular, represents a transverse approach of this study between Paleontology, Zoology, and Molecular Biology. The results of this project will yield the most complete phylogeny of the genus Equus thus far, pushing forward the current state-of-the-art and clarifying the evolution and origin of the living zebras and asses. Moreover, this project will also provide important information for the Conservation (Paleo)biology of these threatened and endangered wild animals.

Mots clés : vertebrate paleontology paleoproteomics equids geometric morphometrics phylogeny

Participants :
- Université Pompeu Fabra (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut català de paleontologia fundacio privada (Espagne) — Coordinator, beneficiary, Recherche, subvention : 194074.56 €
Projet HYBWORKEXP (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

In October 2023, Claudia Goldin became the third woman ever to win the Nobel Prize in Economics and the first woman to win it independently. Her groundbreaking research on women’s labor market outcomes emphasized the need to restructure jobs and compensation to provide more temporal flexibility, a crucial factor in reducing the gender pay gap. Goldin's work highlights the importance of flexible work arrangements in advancing gender equality.  As remote and hybrid work models become more widespread in the post-COVID-19 landscape, they offer the potential for greater flexibility, yet they also present challenges in maintaining sustainable work-nonwork boundaries and ensuring equal career opportunities for women. Existing research presents conflicting evidence on whether these models effectively enhance work-life balance, particularly for women who bear the "triple burden" of professional, household, and caregiving responsibilities.  This research investigates how professional women construct and navigate work-nonwork boundaries in hybrid work settings and how these experiences influence their career trajectories. Through qualitative, longitudinal methods, the study will capture the complex, intersectional challenges faced by women, addressing key questions about intersectional aspects-such as age, race, disability, socio-economic status, and caregiving responsibilities- that shape women's experiences. The findings will provide evidence-based insights into the impact of hybrid work on women’s career aspirations and long-term professional development.

Mots clés : work nonwork boundaries, professional service firms, women, intersectionality, qualitative research, reflexive thematic analysis, interpretative phenomenological analysis

Participants :
- ISM University of Management and Economics (Lituanie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 196976.16 €
- École supérieure des sciences économiques et commerciales (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet REMAKING (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

This project is designed to address the longstanding masculinist interpretation of visual art in the decades immediately following the WWII in Europe. Since the 1950s, the aesthetics of art in this period – of rough surfaces, violence, and gestural grandeur – has been interpreted in essentially masculine terms as interrogating ‘man’. Yet women sculptors and painters were among the most important artistic innovators shaping new directions for European modern art. This project examines how women artists in this period shaped new artistic practices and artistic identities in a transformed postwar environment. By developing new multidisciplinary historical and theoretical frameworks that combine feminist, queer, and ecological approaches, it seeks to forge a new interpretation of postwar art-making that no longer perpetuates the myth of the lone male hero. The project will be undertaken under under the supervision of Elissa Mailänder, at the Sciences Po Centre for History (CHSP), whose connections, experience, and research expertise on gender, violence, and WWII, are acutely relevant. The CHSP will also offer expert interlocutors for the project including world-leading art historian on post-WWII France, Laurence Bertrand Dorléac. Since my aim is to help change widespread cultural perceptions, a key project objective is to communicate results widely. I will produce open-access research articles, an online essay, an exhibition, a major conference open to the public, and an eventual monograph. Building on current public interest in modern women artists, and my proven communication skills, most outputs will be relevant to both public and scientific audiences. The action is also designed to strengthen a range of research and transferable skills, and to reinforce the interdisciplinarity of my research. It will establish me as an international researcher and communicator of important themes in modern art and culture, enabling ongoing knowledge-exchange across the ERA.

Mots clés : modern art, postwar europe, french occupation, women artists, twentieth century france

Participants :
- Fondation nationale des sciences politiques (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 211754.88 €
Projet TransClima (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

The most recent report of the IPCC-AR6 indicates that coastal areas are at risk under the climate emergency that the planet faces, and now more than ever, adaptation is an urgent need. Although remarkable efforts have been made to quantify future changes in the primary climate-related drivers of coastal flooding and erosion risk (waves, sea level rise, and storm surges), these are not yet fully understood. Due to the displacement poleward of Tropical and Extratropical Cyclones in a changing climate, the ocean waves and total sea levels that they induce could hit regions they did not affect before. For the purposes of this proposal, these new regions that will be exposed to new weather conditions are called Transitional Climate Regions (TCR) and Neo-Climate Regions (NCR). Even though these transitional climate regions have been highlighted as critical for ecosystem conservation, they are far from being identified and not even close to becoming part of the coastal risk agenda. This project aims to detect TCR and NCR in the projected scenario SSP5-8.5, by proposing a probabilistic framework of waves and total sea level, under prevailing and extreme conditions (extratropical and tropical cyclones) in coastal areas. These regions are prioritized under socioeconomic and ecological criteria for establishing recommendations. The project, instead of proposing new datasets, proposes a cutting-edge spatiotemporal exploration of coastal hazards by using Machine Learning approaches and a new mindset for climate risk. Once climate and exposure regions are identified, the developing guidelines for coastal risk assessment in these areas will be established.

Mots clés : tropical cyclones, extratroplical cylcones, coastal hazards, ocean waves, storm surge, total water level

Participants :
- Fundacion instituto de hidraulica ambiental de cantabria (Espagne) — Coordinator, beneficiary, Recherche, subvention : 165312.96 €
Projet RUNAWAY (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The case of Yugoslav prisoners of war (POWs), held in Italy from the invasion of Yugoslavia in April 1941 until their mass escape following the Italian capitulation in September 1943, is still overlooked in the literature on WWII. However, it reveals crucial dynamics of the history of 20th century Europe: the fascist imprisonment system; the diverse (civil and international) forms of resistance; and the interplay between wartime memories and the Cold War geopolitical divisions arising after 1945. RUNAWAY aims to: 1) map the Yugoslav POWs’ trajectories during the war (camps, escape routes to Switzerland) and in the aftermath (repatriation or migration); 2) illustrate how these trajectories were shaped by encounters with Italian civilian helpers and partisans; 3) in-depth analyse how their overall experiences as prisoners and fugitives were transformative to their own identities, decisions and memories over time. RUNAWAY is based on a mixed interdisciplinary methodology which, through a wide range of archival searches and oral interviews in Switzerland, Italy, Serbia and Slovenia, integrates tools of military, social and political history combining paradigms of micro- and macro-history. It ambitiously bridges academic research with digital and public history through dissemination tools (maps, databases, hiking trails’ plan) which will contribute to raise public awareness of the Nazi-fascist invasion of Yugoslavia and its consequences, aligning with the commitment to preserve the legacy of European history as a pillar of EU values. The training and research activity conducted within the project will significantly expand the research’s competencies in social, political, digital and public history.

Mots clés : yugoslavia, prisoners of war, italy, world war ii, civil resistance, international resistance

Participants :
- Istituto piemontese per la storia della resistenza e della società contemporanea "giorgio agosti" (Italie) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Turin (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 412700.52 €
- Université de Lausanne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet KNOW-EM-FUNGI (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Fungi play an essential role in Earth’s ecosystems, yet they have historically been marginalized in both academic and public discourse. This project aims to address this gap and investigate its origins by exploring how mushrooms were perceived and understood in Italy, from the 16th to 18th centuries. During this period, Italy was pivotal in developing new understandings of nature, including mycology, primarily with Pier Antonio Micheli. However, the socio-cultural history of mushrooms and its connections with scientific knowledge remain underexplored. KNOW EM FUNGI (KNOWing Early Modern FUNGI in Italy) combines methods of the history of science and knowledge studies to investigate the evolving perception of mushrooms in early modern Italy through culinary, medical, literary, and scientific sources. The project places special emphasis on the proximity between women and mushrooms in artistic representations. It aims to map the nature of such social knowledge by identifying people, practices, communication networks, and places where knowledge exchange occurred. By examining how non-experts contributed to the budding field of mycology, this project challenges traditional narratives and highlights the interconnectedness of social and scientific knowledge. Through secondments at the University of Turin’s Department of Life Sciences and the Naturalis Biocenter in Leiden, I will deepen my understanding of mushroom biology and enhance my science communication skills. A placement at the Fondazione Golinelli will further support my training and allow me to teach school students about the importance of fungi for soil, the environment, and human life. This Fellowship will enable me to contribute to the academic understanding of mycology’s history and empower me to communicate the ecological importance of fungi to a broader audience. The skills and knowledge gained through this project will enhance my academic credentials and career prospects, both within and beyond academia.

Mots clés : mushrooms, early modern science, scientific practices, mycology, ulisse aldrovandi, ferdinando marsili, pier antonio micheli, cultural representations, popular knowledge, social practices

Participants :
- Université de Turin (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Bologne (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 465071.34 €
- Fondazione golinelli (Italie) — Partner, associated partner, Autres, subvention : 0.0 €
- Naturalis Biodiversity Center (Pays-Bas) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Lausanne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet QuantPhases (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

In this action, I propose to extend into new directions the already existing deep connections between quantum error correcting codes and exotic phases of quantum materials. Recent developments in analogue and digital quantum devices call for an extension of our understanding of phases of matter to new regimes, and my project will tackle two such directions: non-Euclidean geometries and dissipative open systems. Both of these are also highly relevant to the quest to develop workable quantum error correcting schemes, which will be crucial to scaling up existing quantum computers.  Recent years have seen breakthrough theoretical results in the field of quantum error correction, which utilize spatially non-local connections to outperform previous constructions. I will investigate these from a physical perspective, and use them to develop theories of quantum phases in unusual geometries and the novel phenomena that they host. Doing so will both open up new questions in the field of condensed matter physics and also shed new light on properties of such error correcting codes and help design new ones.  Error correction arises from a competition of two different dissipative processes: those that cause the errors and those that are engineered to correct them. Designing better error correction schemes therefore requires a deeper understanding of what qualitatively different behaviors can arise in such dissipative systems and to extend the notion of phases of matter to this context. This will lead to ideas that can both help design better error correcting schemes, while also generalizing to other open quantum systems, relevant for various emerging quantum technologies.  During the action I plan to work on these problems under the guidance of a supervisor who has an outstanding track record in the field of theoretical condensed matter physics, with particular expertise in describing dissipative quantum systems.

Mots clés : quantum phases of matter, quantum error correction, open quantum systems, tensor networks

Participants :
- Université polytechnique et économique de Budapest (Hongrie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166903.92 €