Projet Phys2BioMed (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks
Panel : Physics
Statut du projet : CLOSED

Phys2BioMed will offer excellent interdisciplinary and cross-sectoral training to a team of motivated early stage researchers (ESRs) on the application of cutting-edge physical tools for the mechanical phenotyping of cells and tissues of clinical relevance, aiming at developing novel early-diagnostic tools. The Phys2BioMed network will merge diverse competences at European level, from different fields like nanoscience and nanotechnology, physics, biology, and medicine, and will expose ESRs to the non academic and private sector. A key element of the project is the peer-to-peer collaboration of research academic institutions with industries and world-leading medical and clinical centers; these are the main actors of the global challenge against diseases, and within Phys2BioMed they will highlight unmet clinical needs, and actively cooperate with academic colleagues for developing novel diagnostic strategies. ESRs will be trained-through-research by world-leading junior and senior PIs, and will benefit of lecture courses, dedicated international schools and workshops, and topical conferences. Secondments to other nodes of the network will represent the main and more effective channel of dissemination and cross-fertilization of competences, ideas, and knowledge within the network. Besides training talented young scientists, ready to work at the boundary of diverse disciplines in the field of nanomedicine, Phys2BioMed will provide scientific and technological outcomes on biomechanics, and the mechanical determinants of diseases. Technology-wise, it will define standardized procedures for nanomechanical measurements, and the definition of the main features of new-generation instrumentation optimized for the mechanical phenotyping of clinical specimens. In the longer-term, Phys2BioMed will provide the platform and know-how to build a data bank of mechanical fingerprints of diseases, setting the ground for the development of effective early-diagnostic tools.

Mots clés : mechanics and rheology of cells, tissues, and ecms in health and disease, cancer cells, mechanical phenotyping, early diagnostic tools, standardization, atomic force microscopy, nanoindentation

Participants :
- University of Bremen (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 505576.8 €
- University of Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 522999.36 €
- Vmicro (France) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Commissariat à l’énergie atomique et aux énergies alternatives (France) — Partner, beneficiary, Recherche, subvention : 274802.04 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 549604.08 €
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 274802.04 €
- University of Münster (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 252788.4 €
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 261499.68 €
- Centre hospitalier régional universitaire de Lille (France) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Centre hospitalier universitaire Grenoble-Alpes (France) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 274802.04 €
- Optics11 bv (Pays-Bas) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 265619.88 €
- Institute for Bioengineering of Catalonia (Espagne) — Partner, beneficiary, Recherche, subvention : 501809.76 €
- University of Erlangen-Nuremberg (Allemagne) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Jagiellonian University (Pologne) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Polish Academy of Sciences (Pologne) — Partner, beneficiary, Recherche, subvention : 227478.6 €
- Biomeca (France) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €