Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet MRI-Turbulent-Disk (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The magnetorotational instability (MRI) is the most promising candidate for driving turbulence, resulting in angular momentum transport and accretion in astrophysical disks, and is currently at the forefront of research. Despite enormous progress in the last decade, important issues regarding the numerical convergence, dependence of the sustenance and transport properties of MRI-turbulence on viscous and Ohmic dissipation as well as the nature of MRI–dynamo still remain unresolved. The project, going beyond the state of the art, aims at clarifying these issues by using numerical simulations and a new approach of a detailed analysis of dynamical processes in 3D Fourier space, underlying the turbulence sustenance. This study will provide a deeper insight into the dynamics, not accessible in physical space, as done in previous studies. The project is built on my recent findings in MHD turbulence in shear flows – on the new concepts of shear-induced spectral anisotropy, nonlinear transverse cascade and vital area, which lie at the basis of the sustenance of shear MHD turbulence, whose special case is MRI-turbulence in disks. This is its main originality. I will work under supervision of Prof. M. Pessah, expert in MRI, in the Niels Bohr Institute, which is an ideal place due to vast theoretical and numerical expertise of its staff in astrophysical fluid dynamics, MHD and, particularly, MRI and due to powerful computing resources. I will acquire valuable skills in: numerical methods, parallel computing, modeling of specific aspects of astrophysical fluid dynamics and (non-ideal) MHD, grant writing, etc. through advance training from the group members. This will be coupled with rich outreach/teaching programs to enhance my pedagogical skills. Thanks to the Marie Curie Fellowship, all these essential components will enable me to pursue my independent scientific career in Europe, promote my results, develop innovative projects and establish myself as a prominent scientist.

Mots clés : accretion disks, instabilities, magnetorotational instability, magnetic dynamo, turbulence, magnetohydrodynamics, numerical simulations

Participants :
- University of Copenhagen (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 212194.8 €
Projet ENACT (Horizon 2020, appel à projets 2014)
Action : Staff Exchanges
Panel : Chemistry
Statut du projet : CLOSED

The main aim of the ENACT project is to combine computer simulation with materials synthesis and experimental characterization to optimize the design of liquid-phase systems for chemical technologies. By optimization, we understand an improvement in efficiency, sustainability and environmental impact. The quest for such processes is rapidly becoming a necessity in a global scale. Air pollution, energy shortages, and global warming are very serious matters, whose remediation we embrace here as an integral part of the research agenda. This goal will be achieved by first gaining an understanding of the structural, dynamical, and thermodynamic properties of a variety of systems by means of computer simulation. This will allow us to tune their properties by modifying at will, in silico, the choice of materials and external conditions. This knowledge will be then transferred to the experimental partners who will synthesize and characterize the selected systems. If they do not perform as expected, or prove difficult or expensive to produce, a new computational cycle will be required. If they do work, simulation will be used again to fine-tune them. A particularly innovative aspect is that six independent themes will be tackled in parallel under a single umbrella, thus enabling the exchange of ideas and methods between them and paving the way to unexpected technologies arising from cross-fertilization between the various themes. This programme will be accomplished with the participation of four institutions: QUB (UK), UCD (Ireland), ISIS (UK) and UNCUYO (Argentina) with complementary expertise in various aspects of materials modelling, synthesis and characterization. To exploit in an optimal way this distributed expertise, a generous scheme of training (School and Workshops) and secondments has been put in place for ESRs, with shorter visits of ERs. Outreach activities have been included to target the general public and businesses, for exploitation of results.

Mots clés : sustainable, environment, efficient technologies, industrial processes

Participants :
- National University of Ireland (Irlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 139500.0 €
- Queen's University Belfast (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 504000.0 €
- UK Research and Innovation (Royaume-Uni) — Partner, beneficiary, Recherche, subvention : 27000.0 €
- National University of Cuyo (Argentine) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet TECHNOTRAIN (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks - Industrial Doctorates
Panel : Chemistry
Statut du projet : CLOSED

The main aim of “TECHNOTRAIN” proposal (Enabling TECHNOlogies-driven chemistry: a tailored TRAINing research program for batch and flow synthesis of chiral amino derivatives) is to create a training platform for young European researchers, based on the creativity, flexibility and accuracy characteristic of an academic working environment, but with an industrial focus. “TECHNOTRAIN” has the specific objective to develop general, reproducible and also profitable, stereoselective, catalytic synthetic methods applicable for industrial production of enantiomerically pure, functionalized amino derivatives featuring a quaternary stereocenter. Target molecules will be chiral pharmaceutically active ingredients, or immediate precursors, including nonproteogenic alfa-disubstituted-amino acids. The aim is both to synthesize specific target molecules and to develop highly efficient, technology-driven methodologies. Continuous flow processes will be considered, to perform a fast screening of the reaction conditions, and then, with the optimized conditions in hand, to scale up the reaction (by scaling-out or numbering up or scaling-up). The combination of two modern, catalytic strategies (photocatalysis and organocatalysis) with safe and environmental friendly technologies (including the use of 3D-printed devices) is a key step towards the development of a more efficient and sustainable chemistry, in line with the Europe strategy. A future generation of scientists will be trained to face the challenges imposed by the transfer the new, green technologies into industrial processes. Another primary objective of “TECHNOTRAIN” is to develop a modern training model for young European researchers, where education is realized through research and a strong interaction between public and private sector. The project wishes to be truly a prototype of an efficient European research training structure aimed at growing young researchers capable of interacting with the private sector research.

Mots clés : enabling technologies, flow chemistry, 3d printing, organocatalysis, photocatalysis, chiral amines, active pharmaceutical ingredients

Participants :
- Taros chemicals gmbh & co kg (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 784499.04 €
Projet MAYURB (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The main goal of MAYURB is to study ancient urbanism using the Classic Maya Period (250-900 CE) as a model to understand city inception and expansion through time, while considering the diverse actors involved in its planning, use and transformation. The urban fabric of Palenque, Mexico, will be assessed with an interdisciplinary approach that delves into the decision-making process that underlies site planning and considers the limitation imposed by location; in addition, the project ponders the influence of traditions and believes in site selection and religious buildings’ astronomical orientation. While considering the negotiation processes and power relations involved in city inception and growth, MAYURB will explore the unintended consequences of city expansion, such as urban sprawl and sanitation. The project will develop around three main axes: the construction of a GIS platform to join archaeological, architectural and morphological data and to outline the physical reality in which the ancient Maya lived. The spatial analyses performed with GIS will lead the second line of investigation: archaeological excavations at Palenque in areas where it is more likely to uncover infrastructural works and their relative chronology. The third inquiry will explore the extent of authority in site planning and the agency of other urban actors with an interdisciplinary theoretical focus that spans from urban to anthropological theory. The methodological approach and theoretical contribution developed with MAYURB aim at providing a thorough understanding of the planning process and city performance in antiquity, beyond the time period and the geographical location in question. Three unique interchange appointments between UNAM-Mexico, UNIROMA1-Italy and ZRC SAZU-Slovenia at top-level Institutions are planned to fulfill MAYURB’s objectives, while increasing the Experienced Researcher’ skills.

Mots clés : ancient urbanism, architecture, classic maya, infrastructure, site planning, archaeoastronomy

Participants :
- Sapienza University of Rome (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 231524.16 €
- Universidad Nacional Autónoma de México (Mexique) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet SEQOO (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Physics
Statut du projet : CLOSED

The main goal of SEQOO is to realize hybrid quantum systems based on NV-centers in diamond and nanomechanical oscillators. Hybrid quantum systems combine two or more physical systems (e.g. spins, photons, phonons), with the goal of harnessing the advantages and strengths of the different systems in order to better explore new phenomena and potentially bring about novel quantum technologies. While spins and phonons are ideal candidates to store quantum information, photons are ideal carriers of quantum information over long distances. Additionally, mechanical systems can be influenced by a wide variety of small forces and, therefore, present themselves as natural interconnects to realize hybrid systems. Here we focus two realizations of hybrid systems based on Nitrogen Vacancy color center in diamond (NV-center) coupled to a mechanical resonator. The first system consists of an optomechanical crystal (OMC) structure with co-localized photonic and phononic modes, which is formed around the NV defect in the diamond host material. This hybrid system realizes a Spin-Photon-Interface (SPI) operating in the low loss Telecommunications band (TeSPI), which allows for low loss transmission via optical fibres and thereby for connecting spatially separate quantum systems. This is extremely important to realize large-scale quantum networks. The second system consists of a levitated nanodiamond containing a NV-center in a strong magnetic field gradient. The field gradient renders the NVs electronic spin energy dependent on the nanodiamond position and enables cooling of the nanoresonator or preparation of non-classical mechanical states through spin-dependent forces. The Spin Controlled Levitated nanodiamond (SCoL) opens up exciting routes toward studying quantum mechanical effects in macroscopic objects. The proposed research will be carried out in a concerted effort between myself (Dr. Jan Gieseler), Prof. Mikhail Lukin (Harvard University) and Prof. Romain Quidant (ICFO).

Mots clés : optomechanics, diamond, nv center, quantum frequency conversion

Participants :
- Harvard University (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institute of Photonic Sciences (Espagne) — Coordinator, beneficiary, Recherche, subvention : 257191.2 €
Projet 3D-PRESS (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

The main goal of the 3D-PRESS project is to advance in the 3D printing concepts for safer, cheaper and customizable all-solid state Li-ion batteries (LIB). More specifically, the project is focused on the design, production, characterization and testing of 3D printed NASICON-type glass-based electrolytes for 3D printed batteries. In 3D-PRESS, glass-based compositions will be designed and synthesized in order to obtain printable glass-based electrolytes with superior conductivity and functional properties. The produced glasses will be thermally and electrochemically characterized in order to investigate their sinter-crystallization behaviour (tailoring suitable sintering treatments) and electrochemical performances. The most promising electrolyte compositions will be selected to be printed in free-form robust self-standing structures in order to obtain 3D batteries with high active area (allowing high specific energy and power per unit volume). 3D-PRESS represents a cutting edge multidisciplinary approach for the development of reliable and customizable all-solid state 3D LIBs, especially interesting for micro-power applications such as the ones for Internet of Things (IoT). The project will provide a new family of printable materials increasing the short list of available compositions, especially solid electrolytes, opening the door to the development of a new generation of fully printable all-solid state 3D LIBs. A high impact on the future career of the candidate is expected by complementing his current background with new skills in one of the more relevant Key Enabling Technologies (KETs), 3D-printing, applied to the crucial field of the Energy Storage. Moreover, the host institute will offer unique opportunities to re-enforce the technology transfer competences of the candidate by carrying out an industrial secondment and by the involvement in the KIC Innoenergy community.

Mots clés : all solid state battery, 3d printing, electrolyte, glass ceramic, lithium ion battery, 3d battery, 3d lib

Participants :
- CERCA Institution (Espagne) — Coordinator, beneficiary, Recherche, subvention : 160932.48 €
Projet iNano (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The main goal of the iNano project is the development of a new synthesis approach for Indium phosphide (InP)-based semiconductor nanocrystals (NCs), which will be used to record and stimulate neuron activity in dorsal root ganglion (DRG) neuron cells. Although Cd-based NCs are well studied, their application in commercial products is hampered by the presence of the toxic heavy metal ion cadmium. Due to similar optical properties InP NCs are a promising alternative but still facing three major challenges in their synthesis: i) polydispersity, ii) NCs with PL in the NIR region and iii) synthesis of multidimensional NCs. In the iNano project a new synthesis protocol will be established based on a seeded-growth method, which will allow the preparation of monodisperse isotropic and for the first time also of anisotropic InP based NCs. This will be possible by the use of heteroelement seeds (zinc chalcogenides), whose structures govern the InP growth kinetics and shape. The dependency of the PL on the thickness of the InP layer will allow to push the PL to the NIR. By in depth photophysical characterization on the ensemble and single-particle level and also regarding their non-linear properties, unique insights will be gained leading to a better understanding of the optoelectronic transitions and the influence of the shape on the optical properties. iNano will shed a first light into the versatility of the InP NCs for neuroscience, investigating their performance under one-photon and multiphoton excitation to record and stimulate neuron activity. Due to the higher voltage sensitivity, better chemical stability, and negligible photobleaching effects, these nanomaterials are more attractive than up to know used tools for the measurement of the electric field generated by an action potential. The lower toxicity of the InP NCs will making the here developed protocols of high interest to neuroscientist and for the Eu initiative "Human Brain Project".

Mots clés : iii v nanocrystals, seeded growth, two photon imaging

Participants :
- Federal Institute For Materials Research and Testing (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 162806.4 €
Projet RENAISSANCE USSR (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The main goal of the project is to examine the Italian Renaissance Studies in the Soviet Union taken as an independent and considerably isolated scholarly tradition, but placed in the broader context of intellectual history and development of Renaissance historiography in the twentieth century. The project seeks to comprehend why and how Italian Renaissance philosophy, art and history was extensively studied in Soviet Union, what was the contribution of the Soviet scholars to the field on the international level, that is how they reshaped our understanding of this movement, and how these scholars, whose financial opportunities and academic mobility were significantly limited, participated in the international academic networks. The project will be the first comprehensive study of the Italian Renaissance scholarship in the Soviet Union examined as independent national tradition, but placed in the international discourse on Renaissance humanism. The project will contribute to the field of Renaissance Studies, Russian/Soviet studies, comparative and global intellectual history, and gender studies.

Mots clés : historiography of renaissance, renaissance humanism, russian and soviet studies, global history of historiography

Participants :
- Harvard University (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Ca' Foscari University of Venice (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 251002.56 €
Projet Eco-CosmePharm (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The main goal of the proposed research project is the computational evaluation of eco-toxicity (diverse endpoints) of various chemicals that are vastly utilized and produced by the pharmaceutical and cosmetic industries, such as green solvents (including future ones, i.e., ionic liquids and deep eutectic solvents) and active pharmaceutical ingredients (API). We will be majorly focusing on toxicity in aquatic environment, where the toxicity data will cover four trophic levels of aquatic organisms, i.e., fish (vertebrates), invertebrates such as daphnids, algae (aquatic plants), and microorganisms. The toxicity related properties that will be studied include acute and chronic toxicity, biodegradation and bioaccumulation. The research methodology to perform toxicity assessment and for understanding the structural features responsible for the eco-toxicity, will involve diverse Artificial Intelligence (AI) and chemoinformatics techniques like Quantitative Structure-Activity Relationship (QSAR), interspecies QSAR (QAAR), toxicophore mapping, virtual screening, similarity search, clustering techniques, multimedia mass-balance (MM) modeling (to understand the distribution profile of chemicals in different environmental compartments), matched molecular pair (MMPs) analysis etc. The knowledge gained from the study will help in classifying existing chemicals into toxic and non-toxic groups and will also help in designing novel analogues of selected chemical that will show better desirable physicochemical properties with less or no eco-toxicity. This project will also include development of AI software tools and scheming KNIME workflows for various computational tasks.

Mots clés : ecotoxicity, qsar, artificial intelligence, pharmacy, cosmetics, regulatory toxicology

Participants :
- Protoqsar 2000 sl (Espagne) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 172932.48 €
Projet NIMBLIS (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The main goal of this IF research proposal is to produce novel nanoparticle-based multimodal contrast agents for their use in breast cancer diagnosis by combining Magnetic Resonance Imaging, Digital Mammography, X-ray Computed Tomography and Ultrasonography. In doing so, we will develop a new high-productivity strategy to synthesize multimodal hybrid nanoparticles, which consists in femtosecond-laser-induced-ablation of a metal plate immersed into a solvent containing chemicals, in combination with direct nanosecond-laser photolysis in solution of these chemicals. This research will be coupled to an in situ study of the high-productivity laser fabrication process and the analysis of the underlying mechanisms which allows the nucleation and growth of these hybrid nanoparticles. Moreover, we will analyze the structure, composition, physical and colloidal properties of the as-synthesized hybrid nanoparticles, as well as the in vitro performance of these nanoparticles as contrast agents in Magnetic Resonance Imaging, Ultrasonography and X-ray imaging techniques. We will also evaluate the citotoxicity of the as synthesized hybrid nanoparticles in normal cells and tumor breast cells lines. Finally, we will target these nanoparticles toward the human epidermal growth factor receptor 2 (HER2) which is overexpressed in breast cancers with a poor prognosis and higher disease recurrence, and we will evaluated in vitro the targeting ability of the obtained anti-HER2-nanoparticles conjugates for HER2+ breast cancer cells.

Mots clés : ultra short pulse laser ablation in liquids, laser solution photolysis, synthesis of multimodal nanoparticles, colloidal dispersions, ultrasonography, digital mammography, x ray ct

Participants :
- University of Vienna (Autriche) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166156.8 €