Projet In2PrimateBrains (Horizon 2020, appel à projets 2020)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

In2PrimateBrains proposes a highly competitive training-through-research program dedicated to the study of neuronal intra- and inter-areal communication in non-human primate (NHP) brains. This program will empower the next generation of researchers with best practices and cutting edge methodologies for studying complex neuronal activity from multiple brain areas and across cortical layers. Our core scientific goals are to identify common and specific bottom-up and top-down communication principles across NHP brain networks for vision, motor control and executive functions. These functions are especially well developed in primates, and we propose to study them in a brain model as close as possible to the human brain: the NHP brain. Critically, detailed insights into the local- and long-range dynamics of communication, down to the single-neuron level and at millisecond precision, necessitate invasive recording, stimulation and inactivation techniques precluding human investigations. The project entails 9 work packages with well-defined tasks to ensure success in our research and training objectives. We propose tailored research training by world-leading European researchers from the academic, clinical and industrial sectors. This will be accompanied by a comprehensive program of network-wide training events including thematic workshops in essential research-related skills and soft-skill training sessions to ensure successful careers in public or private sectors. The direct experience and acquired expertise in state-of-the-art NHP research and technology development in different environments will drive our ESRs to pursue international, interdisciplinary and intersectoral careers. In a highly competitive international environment, In2PrimateBrains will ensure that Europe remains at the forefront of primate brain research in health and disease with scientists trained by the highest scientific, methodological and ethical standards.

Mots clés : non human primate, brain, integrative neuroscience, translational research, clinical models, brain dysfunctions, pathologies, pre clinical, complex cognitive functions, intersectoral, ethics

Participants :
- Foundation for Research and Technology Hellas (Grèce) — Partner, beneficiary, Recherche, subvention : 243017.64 €
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 274802.04 €
- University of Bremen (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 252788.4 €
- Sapienza University of Rome (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 261499.68 €
- Aix-Marseille Université (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 824406.12 €
- ATLAS Neuroengineering (Belgium) (Belgique) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 256320.0 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 274802.04 €
- Ludwig-Maximilians-Universität München (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 252788.4 €
- Leibniz Association (Allemagne) — Partner, beneficiary, Recherche, subvention : 505576.8 €
- Labcorp early development services gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 252788.4 €
- Newcastle University (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 606345.12 €