Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet TRACE-MP (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Plastic pollution poses a significant threat to human health, particularly through the infiltration of microplastics (MPs) into the body. Emerging studies have detected MPs in various organs, with food and drinking water identified as major sources of exposure. While clinical studies suggest potential links between MPs and conditions such as thrombosis, liver cirrhosis, and endometriosis, a critical gap remains in understanding how the physicochemical properties of MPs, altered by environmental weathering, influence their ability to permeate biological barriers like the intestinal lining—a key gateway to systemic exposure. The TRACE-MP project (Tracking the Penetration and Circulation Effects of Environmental MicroPlastics) addresses this gap by investigating how environmentally relevant MPs, specifically those prepared by artificial weathering and with bio-coronas (BC) formed through interactions with proteins and lipids in the gastrointestinal tract and blood, permeate the intestinal barrier and induce vascular endothelial leakiness. This research will utilise advanced in vitro models, including static and dynamic systems, to simulate realistic biological conditions. The project’s objectives include: (1) characterising bio-coronas on MPs in the gastrointestinal and blood environments, (2) evaluating the permeation of MPs-BC complexes through the intestinal barrier, (3) assessing their potential to induce endothelial leakiness, and (4) correlating these findings with the physicochemical properties of MPs to perform a comprehensive risk assessment. By advancing our understanding of the mechanisms underlying MPs' systemic distribution and impact on human health, TRACE-MP will inform regulatory policies and mitigation strategies to protect public health from plastic pollution. This interdisciplinary approach, combining chemistry, toxicology, and medical biology, is timely and crucial given the growing evidence of MPs in human tissues and their potential health risks.

Mots clés : microplastic, toxicology, intestinal barrier, endothelial leakiness, biocorona, artificial weathering, environmental toxicology, plastic pollution

Participants :
- Queen Mary University of London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 292073.4 €
- École polytechnique fédérale de Zurich (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet CABLE-SENS3 (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Alpine snowpack dynamics are crucial to hydropower generation, irrigation, winter tourism, and avalanche and flood forecasting. The ability to predict snowpack fluctuations is essential for ensuring economic stability and public safety in both alpine and downstream regions. However, current snowpack monitoring techniques are labor-intensive and provide only sparse, large-scale data, which limits the capacity to capture rapid and localized changes. This poses a significant challenge in addressing key operational needs. Cryospheric scientists have therefore identified the collection of spatiotemporal data on snowpack variability, particularly along elevation gradients, as a top research priority.  The overall aim of the CABLE-SENS3 project is thus to develop an innovative snowpack monitoring system that addresses these challenges. The project proposes to use passive RFID tags, combined with an aerial RFID reader mounted on a cable car, to continuously monitor snowpack properties across large elevation gradients. This approach offers a breakthrough by merging high-resolution spatial and temporal data—something current methods cannot achieve simultaneously. Additionally, the proposed system is non-invasive, overcoming the limitations of traditional methods that rely on low-frequency or intrusive measurements. Incorporating technologies such as photogrammetry and microwave geophysics will enable the system to measure variables like snow water equivalent (SWE), liquid water content (LWC), and snow depth.  By deploying RFID tags across large, often inaccessible areas, and conducting frequent aerial surveys, the project will generate unprecedented spatiotemporal data on snowpack dynamics. Such data will be invaluable to stakeholders such as hydropower companies, ski resorts, and avalanche safety services, who increasingly depend on data-driven decision-making. Moreover, the project will provide critical data to address many scientific questions related to the impacts of cli

Mots clés : snow science avalanches snowpack dynamics aerial remote sensing distributed sensing radar insar rfid passive microwave sensors

Participants :
- Mnd france (France) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Pise (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut fédéral de recherches sur la forêt, la neige et le paysage (Suisse) — Partner, associated partner, Recherche, subvention : 0.0 €
- Météo-France (France) — Coordinator, beneficiary, Recherche, subvention : 461934.3 €
Projet PRAWN (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

PRAWN proposes to conduct the first extensive archaeological and archaeometric investigation of metal defensive armour discovered at the underwater site of the Battle of Egadi, Sicily, Italy (241 BCE). As the final confrontation between Rome and Carthage during the First Punic war (264-241 BCE), the Battle of Egadi played a pivotal role in Mediterranean history, enabling Roman expansion through the central-western Mediterranean by defeating the Punic Empire’s hegemony in Sicily. By applying an integrated, interdisciplinary and multivariate methodology to the recovered artifacts from the submersed site, PRAWN aims to: 1. Develop a comprehensive understanding of the panoplies of the naval warriors involved in the First Punic War (e.g. Roman, Punic, Iberian, Numidian, Gallic, Balearic, Hellenistic, etc.) in terms of typologies, manufacturing, provenance of primary materials and use. 2. Identify metallurgical production groups and gather unprecedented information on copper metallurgy in the central-western Mediterranean during the 1st millennium BCE, including the poorly documented Punic metalworking crafts. 3. Elaborate new tools and protocols for cross-referencing archaeometallurgical results, focusing on samples’ representativity in Heritage Science, in terms of alloy chemical composition and microstructure, and create the first FAIR database on body armour from the Mediterranean western area during the Iron Age, starting with PRAWN’s results.

Mots clés : underwater archaeology, metal armour, metallurgy, copper metallurgy, naval battle, punic war, sicily

Participants :
- Centre national de la recherche scientifique (France) — Partner, associated partner, Recherche, subvention : 0.0 €
- École française de Rome (France) — Coordinator, beneficiary, Recherche, subvention : 193643.28 €
Projet SNAC2K (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

The United Nations has expressed concern over the potential weakening of the Atlantic Meridional Overturning Circulation (AMOC) in the next century, which could cause climate and weather alterations that lead to various socio-economic stresses, especially in agriculture, fisheries, infrastructure maintenance and social migration. The value of information associated with a continuous observational record of the AMOC system, which enables confident prediction of future trend, has been estimated to be tens of billions of euros. While instrumental observations of the AMOC system are only available for the last decades, we must rely on proxy indicators in natural archives to capture the long-term trend of ocean circulation throughout the Industrial Age, and further back in time when there were little anthropogenic carbon emissions. Such a long-term record is particularly important for the subpolar North Atlantic: a region of deep convection that maintains the AMOC, susceptible to freshening as a result of increasing Arctic ice melt. This project aims to develop the first comprehensive, long-term record of subpolar North Atlantic circulation through cross-disciplinary, cross-border collaboration between the French Institute for Ocean Science (host), University of Iceland (secondment), and Copenhagen University. The proposed study will compile new proxy analyses with the expanding coverage of instrumental observations to provide a confident reconstruction of the region’s hydrography and dynamics over the past two millennia. Ultimately, the project findings will be effectively delivered to the decision makers, the young generation and the general public through participation in policy works at JPI Oceans (placement), university teaching and outreach activities. The multimodal delivery of project findings aims to raise awareness of the severity of a long-term AMOC decline and to facilitate cooperation for timely mitigation of potential socio-economic consequences.

Mots clés : ocean circulation sediment proxy sediment chronology tephrachronology granulometry ocean data products

Participants :
- Université d'Islande (Islande) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut français de recherche pour l'exploitation de la mer (France) — Coordinator, beneficiary, Recherche, subvention : 244893.6 €
- Joint programming initiative on healthy and productive seas and oceans (Belgique) — Partner, associated partner, Autres, subvention : 0.0 €
Projet MyoPALM (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Duchenne muscular dystrophy (DMD) is the most prevalent form of childhood muscular dystrophy, affecting approximately 1 in 3500 newborn boys. DMD patients experience early-onset and rapidly progressive muscle weakness, leading to the loss of mobility and premature death. The burden of muscular dystrophies extends beyond the physical challenges faced by patients, indeed it poses significant social and economic implications, impacting patients’ quality of life, necessitating social welfare support and incurring substantial healthcare costs. So far there is no cure for DMD, emphasizing the urgent need to intensify research efforts aimed at uncovering new pathomolecular mechanisms and developing treatment strategies. Protein lipidation, especially protein S-palmitoylation, has gained attention in several diseases, but its role in skeletal muscle function and dystrophic conditions remains completely unexplored. MyoPALM is an innovative project that aims to bridge this knowledge gap by investigating the contribution of protein S-palmitoylation in adult skeletal muscle function. This will be accomplished through in vivo manipulation of the enzymes involved with this pathway and using cutting-edge palmitoyl-proteomic approaches. Furthermore, by exploiting the mdx mouse model, we aim to explore the potential role of protein S-palmitoylation in the pathogenesis of DMD. By unravelling this unexplored perspective, MyoPALM aims to lay the foundation for identifying new druggable targets, paving the way for future therapeutic strategies to benefit DMD patients. Through collaboration between the École Polytechnique Fédérale de Lausanne (CH) and the University of Padova (IT), the applicant seeks to reinforce his technical skills and scientific knowledge, aspiring to become an independent researcher within the European Union.

Mots clés : skeletal muscle duchenne muscular dystrophy protein s palmitoylation protein s acylation

Participants :
- Université de Padoue (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 320924.16 €
- École polytechnique fédérale de Lausanne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet PRESERVE (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Coastal areas make up 4% of the world's land surface and protect the majority of the largest cities from severe storms, flooding, and sea level rise with ~40% of the global population living within 100 km of the coast. They also contribute to preserving biodiversity and can store more carbon per hectare than any terrestrial ecosystem. However, coastal wetlands are being lost at an unprecedented rate due to the overwhelming stress caused by human interference and climate change. The resilience of such ecosystems is strictly connected to their elevation with respect to mean sea level, which can be altered by shallow compaction, deep land subsidence, erosion, sedimentation decrease, and sea level rise. For this reason, the conservation of wetlands and related resources has become a major priority of the UN’s Sustainable Development Goals (2015). However, interactions between physical and biological/biogeochemical processes at the plant root level are still largely unknown. PRESERVE aims at providing a quantitative response to the long-term prediction of wetland resilience under climate changes, involving the coupled nature of surface/subsurface processes by investigating the role of vegetation and especially the mutual interactions between roots and soils. PRESERVE is a multi/interdisciplinary project that connects different areas of expertise (hydrodynamics, geomechanics, hydrogeology, wetland dynamics, and ecology) and develops innovative and specifically-designed laboratory and field experiments. The results are integrated within a novel modeling framework and the new knowledge generated in this project will be publicly available in a user-friendly application for end-users to cast nature-based solutions for low-lying coastal systems. PRESERVE is set to reach the goals of the European Green Deal by supporting the EU strategy to become a global leader in preserving and protecting biodiversity and to become the world’s first climate-neutral continent by 2050.

Mots clés : wetlands, tidal environments, geomorphological evolution, land subsidence, nature based solutions

Participants :
- Université de Padoue (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 288859.2 €
- Université du Delaware (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- We are here venice (Italie) — Partner, associated partner, Autres, subvention : 0.0 €
Projet HEMZAB (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The growing concern regarding non-renewable fossil fuels and their adverse environmental impact has spurred the increasing exploration and utilization of renewable energy sources and the increasing development of energy storage devices. Within the energy storage systems, reversible batteries are the most performant in chemical-to-electrical energy transformation and vice versa. Currently, Li-ion batteries are dominating the energy storage market, though limited supply, high cost and safety concerns of the key material i.e. Li, is pushing the search for alternatives. In this regard, Zn-air batteries are the rising star of the future for Li-ion replacement. Yet there are two major challenges in the widespread adoption of Zn-air batteries: (i) sluggish oxygen redox (ORR/OER) reactions and (ii) instability of cathodic materials. This proposal will develop multi-component high entropy metal chalcogenides as bifunctional air cathodes having multiple active sites with tunable oxygen adsorption energies. Such a configuration will enable the facilitation of both ORR and OER effectively. In addition, it will enhance the stability of the cathodic catalysts. So the main goal of the project is to “Build a better Battery” by developing cost-effective, non-toxic and efficient catalysts that can boost the energy and power density of Zn-air batteries and enhance the stability of air cathodes. HEMZAB’s achievements will make advancements in cutting-edge Zn-air batteries that are pivotal to reaching the EU’s environmental targets for a reliable and green energy transition at a low cost.

Mots clés : high entropy metal chalcogenides, zinc air batteries, bifunctional catalyst, oxygen reduction, oxygen evolution reaction

Participants :
- CERCA Institution (Espagne) — Coordinator, beneficiary, Recherche, subvention : 165312.96 €
Projet GBV_COP_SOC (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Violence occurs in all countries, rich or poor, developed or developing, irrespective of caste, creed, color, social status, wealth, urban or rural residence, or the ages of victim and aggressor. Keeping this in mind, this study is designed to understand gendered aspects of Gender based violence in Pakistan and Pakistani Families living in Norway. Despite extensive legislation and steps taken by the federal and provincial government, the plague of GBV is at rise in Pakistan and rest of the world. Interestingly, to address the GBV issue at state level, community policing has emerged as an alternative approach to conventional, top-down approach to ensure Human security . Community policing also addresses gender inclusive policing which in response provides room to address serious issues like gender based violence. Such community based approaches to policing are instrumental in addressing the sensitive issues like GBV, however, the effectiveness of these approaches in complexed contexts are under-researched and debated in recent scholarship. Similarly, it is equally interesting to understand the choices people make in legally pluralistic societies because it will provide greater understanding to reflect on how people maneuver, negotiate and choose the legal system to address GBV . At the Norwegian level, it would be very valuable to review how police works with GBV victims from immigrant communities from Pakistan .Hence, there is need to understand the gaps and challenges within the designed mechanism to curb GBV with special focus on gendered social relations, legal pluralism and why it is important for police to understand contextual complexity . Qualitative data collection method will be used to collect data both from Pakistan and Norway. Study is framed from grains from various filed of studies like Security, feminism, IR, Legal and Development Studies to ensure interdisciplinarity.

Mots clés : gender based violence, community policing, alternative conflict resolution, legal pluralism

Participants :
- European union agency for law enforcement training (Hongrie) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Université norvégienne pour les sciences de la vie (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 210911.04 €
Projet Super-CO2 (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Currently, 28.2% of the total EU-28 greenhouse gas emissions come from the power sector, a large contributor to greenhouse gas emissions. Consequently, the emphasis of the research in power generation has swung towards assessing highly efficient and greener power cycles. In this reference, the novel supercritical carbon dioxide Brayton cycle (sCO2-BC) is an ideal choice that outstrips other formally well-known power cycles (Brayton & Rankine cycles). In sCO2-BC, the role of the pre-cooler is critical. It serves as a sink to the power cycle and regulates the conditions at the compressor's inlet. The compressor's inlet temperature is intended to be maintained close to the critical temperature of carbon dioxide (CO2) to achieve greater cycle efficiencies. However, exceptionally higher values of the specific heat capacity of CO2 near its critical point (up to 40 times higher than water) require exceedingly high water flow rates on the cold side to achieve the desired exit temperatures of CO2. Consequently, the pre-cooler's pumping power requirements become high enough to deteriorate the cycle's performance. This problem can only be mitigated by exploring new channel geometries with enhanced thermohydraulic characteristics. Therefore, the proposed study plan to characterize the complex thermohydraulic characteristics in the pseudocritical region of CO2 using a multifaceted technique that includes, experimental, numerical, and machine learning techniques. The proposed work will provide a step forward to the success of sCO2-BC technologies that, in turn, will facilitate its integration with the green energy resources (generation-IV nuclear reactors and solar concentrated plants), helping to meet the EU's 2030 climate and energy framework goals of achieving at least 32% share for renewable energy.

Mots clés : heat transfer supercritical carbon dioxide brayton cycle precooler design, printed circuit heat exchangers design optimization machine learning

Participants :
- Université norvégienne pour les sciences de la vie (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 226751.04 €