Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet ERAP (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Digital platforms can massively erode the social environment in which they operate. For instance, short-term rental platforms (STRs) such as Airbnb dislodge vulnerable locals from their homes, escalate gentrification, and further fuel overtourism. Urban ecosystems develop organized responses to such disruptions ranging from local social movements to international city alliances, which take action to address extensive ‘platformization’. While the knowledge of the systemic effects of the ‘platformization’ of society is increasing, we still know little about the emergent resilient responses and the further effects they set in gear. This project titled "Ecosystem Resilience against Platformization" (ERAP) fills the gap by exploring and theorizing the efforts to counter the negative effects caused by STRs. ERAP employs case study methodology to zoom in on four EU cities where the negative effects of STRs are particularly visible, but the responses are vastly different. The fieldwork focuses especially on giving voice to and learning from underprivileged groups, e.g., tenants at risk of losing housing and housing movements. Complementing that is a longitudinal study tracking the efforts to establish EU-wide STR regulations. Leveraging the novel interdisciplinary field of digital ecology, ERAP will trace patterns of ecosystemic intensifications (e.g., the loss of affordable housing) and the emergent organised resilient responses. The analytical emphasis will be on the configurations of social actors mobilised in those processes, their tactics, the use of digital technology, and interconnections (e.g., alliances), with the goal of explaining the systemic dynamics of digital resilience. ERAP will contribute to the growing field of digital ecology and inform EU's policy on next-generation sustainable digitalisation, emphasising that the future of digitalization is negotiated among a broad range of stakeholders and across levels (from local to transnational).

Mots clés : digital ecosystem ecosystemic resilience digital platform social mobilisation digital short term rentals overtourism digital ecology

Participants :
- École de commerce de Copenhague (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 230774.4 €
Projet BITES (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The relationship between humans and their natural environment has significantly shaped our evolutionary history. Carnivores in particular, our main competitors in many past ecosystems, likely had a profound impact on hominin behaviours. Neanderthals, potentially more carnivorous than other hominin species, present an intriguing focus. Were the relationships between Neanderthals and carnivores primarily rooted in rivalry, mutual avoidance, or subtle survival adaptations? How did they impact Neanderthal niche exploitation? Can changes in these interactions shed light on Neanderthal disappearance? Archaeological sites yield thousands of animal bone fragments with traces of Neanderthal and carnivore consumption that offer valuable insights into this coexistence. Yet, these data remain underexploited, due to the challenges derived from interpreting complex mixed taphonomic processes. The BITES project aims to reconstruct Neanderthal-carnivore interactions using targeted quantitative methodologies, which are tailored to detect patterns previously unattainable with traditional approaches. Employing both multivariate statistics and machine learning, I will initially accurately quantify hominin and carnivore relative activities across four Middle Paleolithic sites in Iberia set in different environments. Subsequently, reusing literature data, the project will build statistical and machine learning models to identify the main interaction type in previously studied sites, including scavenging, avoidance, and competition for prey. Lastly, the project will explore any environmental, spatial, or temporal shifts in these interactions and their potential correlation with settlement patterns and the eventual disappearance of Neanderthals. The findings derived from bridging cutting-edge methods with ancient data promise to reshape our perspective of Neanderthal ecological behaviour and adaptive strategies, introducing fresh, integrative approaches in Paleolithic research.

Mots clés : zooarchaeology, taphonomy, human evolution, neanderthal behaviour, hominin carnivore interactions, quantitative analysis, paleoecology

Participants :
- Université de Heidelberg (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de l'Algarve (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 156778.56 €
Projet LCT (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Currently, cancer is the second cause of morbidity and death in Europe, with 1.9m deaths and 3.7m cases annually. Cancer-related deaths are projected to exceed 13m by 2030, with abdominal organs hosting most cancer incidents. Although popular, conventional modalities are nonetheless associated with major clinical challenges such as non-specificity, side effects, and drug tolerance, which impede further developments. In recent years, non-invasive, controllable, minimal side effects, and localized nano-scale drug-based therapies have been developed. This treatment deploys nanocarriers (NCs) to the location of the targeted cancer tumors, and upon activation, they release chemotherapeutic drugs. However, there are concerns over the safety of this strategy due to lack of biodegradation, potential toxicity, poor bioavailability, and limitations associated with the drug activation protocols. The main goal of the LCT project is to overcome these challenges in an original and innovative manner by developing nanocarriers that are nontoxic, biocompatible, biodegradable, and can be combined with a well-known treatment modality (e.g., a precise and effective radiation treatment). The proposed work will be approached from theoretical, numerical, and experimental perspectives based on the applicant's and host laboratory's expertise. The training program is exhaustive and will allow the applicant to grow as an independent researcher. The proposed research will foster further development in this direction, a step that is fundamental in healthcare and for the benefit of society.  The applicant is a Libyan scholar with expertise in the areas of applied mechanics, industrial & medical radiation, materials science, nano-chemistry, and structural engineering. He has been trained in prestigious industrial and academic institutions in Libya, Canada, and Hong Kong. He is applying for a two-year MSCA fellowship to conduct the LCT at NUI Galway. A 4 months secondment at UCD is planned.

Mots clés : radiotherapy, nanocarriers, cancer, targeted delivery, multimodal therapy

Participants :
- University College Dublin (Irlande) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université nationale d'Irlande à Galway (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 199694.4 €
Projet WAVES (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

WAVES explores and documents the activism of the organisation Women of Sacrifice Zones in Resistance in Quintero-Puchuncaví, Chile. These areas, severely impacted by industrial environmental degradation, disproportionately affect marginalised communities, particularly women. The project fills a research gap by examining the intersection of gender, environmental justice, and political activism in the Global South—an area often overlooked in favour of studies focused on the Global North. WAVES employs an innovative multimodal methodology combining Photovoice and participatory video, empowering women to document and narrate their experiences of environmental injustice. The project will produce a documentary, exhibited in Chile, the UK, and Spain, providing these women with a platform to intervene in public discourse, reshaping the representations of women activists in sacrifice zones. Beyond academia, WAVES aims to influence policy discussions, amplify marginalised voices, and strengthen community resilience, focuses on the social impacts of environmental degradation on women’s lives and highlights their strategies for resistance. The researcher will receive technical and theoretical training at the School of Film, Media, and Creative Technologies at the University of Portsmouth and the Anthropocene Research Centre at University College London, gaining competencies in Photovoice, participatory video, and theoretical frameworks on the social impact of environmental crises. This will reinforce European interdisciplinary networks, contributing to dialogue between the Global South and Europe. The name WAVES symbolises the ongoing efforts of women activists, whose actions—like the waves of the sea—continuously shape and influence both local and global environments, embodying resilience and transformation.It also refers to the maritime contexts of the research: Valparaíso, Portsmouth, London and Barcelona.

Mots clés : women, photography, film, activism, enviromental justice, sacrifice zones

Participants :
- University College de Londres (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Portsmouth (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 276187.92 €
Projet RESOLUTE (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Climate change and river fragmentation are interacting in Europe's rivers to drive population extinctions of cold-water fishes, including those of the Salmonidae family. The effects of extreme warming in summer can be mitigated by increasing the provision of cool-water refugia through nature based solutions (NBS) that provide salmonid fishes with optimal rather than critical temperatures. However, the fishes must be able to access these refugia, which can be difficult in highly fragmented rivers, unless fish pass engineering is applied to the barriers fragmenting the river. The beneficial interactions of NBS and fish pass engineering on salmonid populations are, however, unknown. While they could facilitate behavioural thermoregulation, where fish actively move from warm areas into cooler waters (often moving >10km), fish passes also impose considerable inter- and intra-specific selectivity of fishes, often only being passable of specific size ranges and behavioural phenotypes (e.g. proactive individuals with bold, exploratory behaviours). Consequently, mitigating for warming and river fragmentation using NBS and fish pass engineering could result in considerable modifications to the diversity and distribution of fish species and phenotypes in Europe's rivers. This project aims to overcome these considerable knowledge gaps on how NBS and fish pass engineering can act in concert to provide sustainability in cold-water fishes in warming and fragmented rivers. The complementarity of an outstanding researcher in applied fish ecology with a European research group with exceptional expertise in fish spatial and trophic ecology will complete an empirical study based on fish biotelemetry methods in a natural field experiment testing relevant hypotheses within four NBS/ fish pass scenarios. The generated empirical data are then used as the basis for predictive models for simulating the outcomes of different scenarios of warming and fragmentation of global relevance.

Mots clés : fish pass science, acoustic biotelemetry

Participants :
- Université de Bournemouth (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 260347.92 €
Projet HERO4PFAS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Per- and poly-fluoroalkyl substances (PFAS) are a group of man-made chemicals produced for several applications, ubiquitous in water bodies close to industrialised regions, and with recognized associated issues to human health (e.g. carcinogenicity). Being among the most recalcitrant class of emerging contaminants, an efficient water treatment able to degrade PFAS will represent an outstanding technology, not only for the recovery of already contaminated sites (impressively spread in Europe), but also for drinking- and waste-water treatment plants. The project proposal, “Hydrated Electrons from iRradiated metal-free semicOnductors for PFAS degradation in water (HERO4PFAS)”, focuses on the development and investigation of wide band gap semiconductors able to photo-produce hydrated electrons under ultraviolet (UV) light to eliminate PFAS from water. The main goal will be to evolve from the state-of-the-art homogeneous advanced reduction processes (ARPs) towards heterogeneous systems to be employed in real cases. Since very expensive materials are required to photo-produce hydrated electrons (e.g. diamond-carbon), in this project low-cost photocatalysts based on hexagonal boron nitride will be prepared, and their ability in the degradation of PFAS studied under different conditions (type of irradiation, pH, dissolved oxygen). Systems based on heterogeneous UV-ARP will be implemented for the removal of PFAS from retentate streams of advanced membrane filtration systems and coupled with advanced oxidation processes in a holistic treatment train able to reach the complete PFAS mineralization. HERO4PFAS will fill the gap between PFAS degradation and the development of a cost-efficient heterogeneous photo-ARP. With the support of my supervisor (Prof. Minella) at University of Turin, I will diversify my individual competences to materials science and UV-ARP chemistry, boosting my career as future expert on photocatalysis and water treatment technology.

Mots clés : water treatment pfas advanced reduction processes hydrated electrons boron nitride carbon diamond advanced oxidation processes emerging contaminants

Participants :
- Université de Turin (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172750.08 €
Projet WellbeMap (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

The United Nations has a goal to promote good health and wellbeing by 2030 (SDG3). The extent to which people are satisified with their neighbourhoods (their residential wellbeing RW) can account for up to 15% of their overall life satisfaction (mental wellbeing). Previous research applied qualitative and quantitative methods to understand the relationship between neighbourhood planning and wellbeing. However, due to the inconsistency in defining the spatial scale of neighbourhood and the failure to capture neighbourhood complexity in analysis, there has not been yet a comprehensive evidence-based framework of neighbourhood planning factors that influence RW. Therefore, this project (WellbeMap) aims to explore the neighbourhood planning and design factors associated with RW and whether those factors are objective or depend on individual residential needs. WellbeMap will take Dublin 8 (D8), a district in Dublin, Ireland, as a case study. It will (i) collect social data to identify subjective neighbourhood boundaries, neighbourhood needs, RW and urban planning data in D8; and (ii) analyse the relationship between urban planning data, RW and neighbourhood needs. Through the combined expertise of the applicant and the supervisor and the research environment at Maynooth University Social Science Institute (MUSSI) and the ADAPT centre, we will translate the concept of RW into a framework of factors that urban planners can control. This will contribute to people's mental wellbeing and, in turn, advance progress towards SDG3. WellbeMap will also have an impact on the applicant and the host organisation through the exchange of knowledge between MUSSI, ADAPT and the applicant. MUSSI and ADAPT will advance the applicant's career by building her capacity in quantitative spatial analysis and Machine Learning, project management and research commercialisation while the applicant will transfer her knowledge on urban design analysis, simulation and planning in Egypt.

Mots clés : neighbourhood satisfaction residential wellbeing gis sdg3 dublin 8

Participants :
- Université nationale d'Irlande à Maynooth (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 252728.64 €
Projet INFEDE (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The aim of the project is to critically examine the factors influencing mothers’ decisions on infant feeding in two different cultural locations: Ireland and Finland and to provide innovative research on women’s experiences of breastfeeding and bottle-feeding. The project highlights that infant feeding decisions are not made independent of social and cultural context. There are two specific objectives: 1) To explore and identify the cultural expectations and policies concerning infant feeding in Ireland and Finland. This objective is the groundwork for RO2, and informants are people working and volunteering in breastfeeding associations and midwife organizations. 2) To research infant feeding as a contextual practice that has personal, cultural, and social levels. This is achieved by analysing the interview narratives conducted with mothers from both countries while being sensitive to intersectional differences and socially constructed subject positions. The research method is qualitative and has an interdisciplinary approach combining content analysis and narrative analysis methods with gender studies, media studies and sociology. An intersectional reading is used while analysing the data. The project contributes to the research of infant feeding and breastfeeding which is set as a health priority throughout Europe. The reasons behind breastfeeding or bottle feeding are various and this research adds knowledge and understanding to the different levels of infant feeding. The breastfeeding rates in selected countries are very different; in Finland over 95 % of mothers initiate breastfeeding while in Ireland the rates are much lower and little more than 60 % are breastfed. This makes Ireland’s breastfeeding rates one of the lowest in the EU. Still, both countries are affected by the savings targeted to maternity services, the lack of support in the early days of mothering, the pressures of profit gaining formula industry, and the constant sexualisation of breasts.

Mots clés : mothering, infant feeding decisions, contextuality, intersectionality

Participants :
- Université nationale d'Irlande à Maynooth (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 215534.4 €
Projet MicroBED (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Binge Eating Disorder (BED) is a psychiatric disorder with grave health risks. Previous studies have associated alterations of gut microbiota status with BED. However, whether this is a causal relationship, where differences in gut microbiota status promote binge-like eating behavior independent of changes in body weight remains to be explored and forms the central aim of MicroBED. MicroBED will also characterize the influence of gut microbiota on behavioral outcomes relevant to BED via the hedonic feeding circuit. Lastly, MicroBED will explore whether certain microbial metabolites can alleviate binge-like eating behavior. It hypothesizes that gut microbiota influences BED associated behavior by altering activation of the hedonic feeding circuit, via circulating microbial metabolites.  MicroBED will be performed in the Weizmann Institute, one of the world’s leading multidisciplinary basic research institutions. It will be highly interdisciplinary and involve collaboration with renowned neuroscientists and computational biologists. The outcomes of MicroBED could have significant societal impact as it can lead to development of novel therapies for BED. General public, policy makers and scientific audiences will be informed about the outcomes of MicroBED through a multi-pronged dissemination strategy.  MicroBED will also greatly aid my career development by providing world-class training in a multidisciplinary setting. It will enhance my research skills, foster my managerial abilities, and strengthen my professional network. I will also benefit from the high-level training provided by the Feinberg Graduate School, including courses and workshops in technical and soft skills, and by attending international conferences like FENS and SfN. To conclude, MicroBED will provide an important opportunity in my career, that would allow me to acquire critical skills and competencies, that will enable me to transition from an early career scientist to research group leader.

Mots clés : host microbiome interaction

Participants :
- Institut Weizmann (Israël) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 200538.24 €
Projet PRELEUKMEC (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Clonal Hematopoiesis (CH) is an age related state in which a single and genetically defined Hematopoietic Stem Cell (HSC) contributes more than expected to the hematopoietic pool, due to the selective advantage conferred by genetic variants termed preleukemic mutations (pLMs). CH is a significant risk factor for hematological malignancies such as Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS). Today, the mechanisms by which pLMs provide selective advantage and why in some cases clones become leukemic is not fully understood. This project focuses on understanding the dynamic changes that occur in human HSCs in aging and disease at the single cell level. Specifically, we wish to answer the following questions: 1) What are the functional consequences of aging on peripheral blood HSCs 2) what are the functional consequences of pLMs in CH, but also in AML and MDS in humans? 3) which microenvironmental factors provide selective advantage to the mutated clones? To answer these questions, we aim at developing a new innovative approach that will allow us to interrogate thousands of single HSCs from young/old/CH/AML/MDS patients to extract their genotype and their dynamic expression profiles at different time point of differentiation, under different culture conditions. This project will be performed in the Weizmann Institute, one of the world’s leading multidisciplinary basic research institutions in the natural and exact sciences. It will be highly interdisciplinary as it will involve collaboration with renown researchers from the Computer Science and the Chemistry department. In addition to the knowledge acquired in the lab and through the different collaborations, the fellow will benefit from high level training through attendance of various courses, seminars and international conferences. Overall, this project should have great benefit for the career of the fellow.

Mots clés : hematopoiesis, aging, single cell rna seq, preleukemic mutations

Participants :
- Institut Weizmann (Israël) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 200538.24 €