Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet SEARCH (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Current global concerns about food security and the impacts of climate change on our existing food systems require innovative and sustainable solutions. Seaweeds are poised to become a sustainable food of the future and will be central to solving impending food crises, mitigating effects of global climate change, and re-invigorating human-ocean relationships. However, a significant barrier to successful uptake of the seaweed industry in Europe is a lack of cultural awareness on local seaweed consumption in human foodways. Human relationships with seaweed and aquatic coastal plants (e.g., seagrass) are historically understudied in archaeology and underappreciated culturally despite the likelihood that these relationships have been central components for past coastal societies, as evidenced by historic and ethnographic research. Understanding past human-algae/plant relationships and cultivation strategies provides key frameworks for contemporary and future strategies involving coastal plant and seaweed foraging, cultivation, and consumption. Such frameworks are urgently needed to build ecologically and culturally sound strategies and to prevent problematic over exploitation of these resources and damage to ecological systems. This project will provide important global advances in environmental archaeology by investigating archaeological seaweed residues and retrieve critical data at a local scale for the future of Northern Europe's seaweed and coastal industries. Past human relationships with seaweeds and coastal plants will be investigated using innovative archaeological science approaches that target microbotanical and micro-algae residues. Through accessing these microremains this project will compile paleoecological data to create a scientifically informed environmental baseline and trace ancient human-plant/algae relationships in northern Europe.

Mots clés : seaweed, diatoms, phytoliths, starch grains, palaeoecology

Participants :
- Université de Stavanger (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 267418.56 €
- Université d'Umeå (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Lofoten seaweed company as (Norvège) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet PBE-FireSeismicRes (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The reusability of steel structures after fire under seismic combinations of actions is particularly important within a variety of disciplines including ecology, sociology, and engineering. The best solution is to assess the reparability and retrofit the fire-exposed steel structures for desired seismic performance on a scientific knowledge base. The proposed PBE-FireSeismicRes project will develop a performance-based engineering framework for assessing and enhancing the seismic resilience of fire-exposed steel structure that is expected to raise major international scientific and industrial interest. This framework will be sophisticated and practical. First, collaborative research efforts will be presented to develop high-fidelity computational models of fire-exposed steel structures to assess the seismic fragility of these structures with various fire and earthquake scenarios. Second, seismic protective technologies will be developed to promote the application of the technologies and design to restore and upgrade the seismic resilience of deficient fire-exposed steel structures. Following this, design criteria, design methodology, and risk-based assessment approach will be established within the performance-based engineering framework to promote the reusability of fire-exposed steel structures. Together, the research outcomes from this project bear the potential to significantly advance the state of art in better safeguarding the built environment against earthquake hazards.

Mots clés : resilience, hazards, earthquake, fire, performance based engineering, steel structures, reusability, structural engineering

Participants :
- École polytechnique fédérale de Lausanne (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Patras (Grèce) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 169326.72 €
Projet SMARTMUS-E (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Fellow: Paola Lucero; Host institution: Palacký University Olomouc (UPOL,CZ); Supervisor: Karel Lemr (Department of Analytical Chemistry, DAC-UPOL) Co-supervisor: Petr Bednar (DAC, UPOL); Host institution and Supervisor secondment: Ca’Foscari University (CFU, IT) Isadora Antoniano; Host institution and Supervisor non-Academic Placement: Gallerie dell’Accademia in Venice (GAV, IT), Silvia Salvini; Aim of the project: RO1: to give to the methodology that I published in 2020, for monitoring and control of fluctuations of temperature and relative humidity in museum environment, a chemical background considering materials degradation; RO2: to gain knowledge into materials degradation and determine what fluctuations can be tolerated by museum objects, without damage; RO3: To gain knowledge on historical buildings behavior and their capacity dumping outdoor weather variations RO4: to transfer the gained knowledge by training an initial set of end-users in cultural institutions to help them managing their energy consumption; Innovation: Creation of a methodology for characterization of museum indoor environment that considers material degradation. Enable conservation professionals to estimate how safe is museum environment in historical buildings under climate change influence. To contribute saving energy by allowing wider yet safe fluctuations of Temperature and Relative Humidity in museums with mechanical air conditioning systems; Procedure and data: Gain knowledge on materials behavior using analytical techniques to characterize degradation in mockup samples naturally and artificially aged and combine this data with the characterization of indoor environment in museums; Results: 2 Journal articles, 4 conference presentations, 7 workshops, 5 public events an online professional forum, online data repository for Temperature and Relative Humidity museum records Partner Institutions: GAV, Český Krumlov Castle, Viking Museum, Hist. Museum of Oslo, Nat. Heritage Institute CZ

Mots clés : analytical chemistry, art materials, natural and artificial aging, energy saving, climate change

Participants :
- Université Palacký (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 207848.4 €
- Université Ca' Foscari de Venise (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Gallerie dell'accademia (Italie) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
Projet EFESTO4EU (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Raw materials are pivotal in realizing the United Nations' '2030 Agenda for Sustainable Development' and its 17 Sustainable Development Goals. Among these critical raw materials (CRMs), are of strategic importance to the EU's economy. However, they face significant supply risks, particularly Rare Earth Elements (REEs), vital in emerging clean technologies. Dependence on REE imports, coupled with geopolitical instability, has driven price spikes, prompting the need for recycling. Currently, no commercial recycling operation exists for end-of-life (EoL) products and their REE content, potentially exacerbating supply-demand imbalances. Recycling CRMs offers environmental benefits, reducing mining's impact, enabling multiple CRM recovery from a single device, and minimizing habitat disruption and water pollution. EFESTO4EU project seeks to advance scientific understanding and develop innovative materials for metal extraction, primarily focusing on recycling REEs from real EoL products using environmentally sustainable technologies. The proposed method involves extracting REEs from the leachate resulting from the pre-treatment and dissolution of EoL products. This process employs a solid/liquid system, utilizing Ionic Liquids (ILs) immobilized on silica-based gel to form a material referred to as ionogel. Subsequently, these ions are released and reclaimed, allowing for the reuse of ionogel in successive cycles. The project has a strong interdisciplinary approach going from material synthesis to solution thermodynamics. To ensure the successful implementation of these project goals, I will conduct my research at Swiss Federal Laboratories (Empa) and University of Udine (Italy), under the guidance of Dr. Wim Malfait and Prof. Andrea Melchior, leading scholars. This project will prepare me to become a tenured scholar and obtain advanced funding, strengthening my academic profile and allowing me to establish my own research group.

Mots clés : rare earth elements critical raw materials thermodynamics speciation

Participants :
- Université d'Udine (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 242881.08 €
- Université de Novi Sad (Serbie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Laboratoire fédéral d'essai des matériaux et de recherche (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet GreenFlux (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Current global warming is faster in the Arctic already affecting the region profoundly. In the Arctic, key players that likely have a strong impact on global warming are permafrost and gas hydrates, because both host large amounts of carbon. Permafrost and gas hydrates also likely occur offshore as relics of the Pleistocene. Current global warming may cause melting of these marine permafrost and gas hydrates and release more greenhouse gases into the ocean or even atmosphere (climatic feedback). However, the geologic processes that govern such melting and the sensitivity to climate change are poorly constrained. Here, I propose an original combination of approaches to assess the contribution of (sub-) Arctic marine gas hydrate and permafrost systems to marine geologic greenhouse gas emissions (GreenFlux). First, I will investigate the sensitivity of these marine systems and associated fluid flow systems to climate change across the NE Greenland shelf by using seismic and acoustic data in combination with paleo-oceanographic proxies from sediment cores. Second, a detailed study of the Kattegat, offshore Denmark, provides an analogue for the spatiotemporal evolution of sub-Arctic fluid flow systems in response to climatic changes. I will compare these two regions, one Arctic and one now temperate, to evaluate how the environmental differences impact gas release and how the Arctic is likely to develop in a future warmer world. GreenFlux will break new ground in our understanding of how climate change will influence marine gas hydrates, permafrost, and associated fluid flow in Arctic regions, and generate new knowledge on how much greenhouse gas these systems contribute to natural geologic emissions. The results will therefore be of importance to a wide audience, ranging from all Earth scientists to policy makers and the general public because they contribute to improvements of climatic models that help us as society predict and deal with the effects of climate change.

Mots clés : permafrost, gas hydrates, fluid flow, paleoceanography, paleoclimate, sedimetology, seismics, hydroacustics

Participants :
- Université d'Aarhus (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 230774.4 €
- Volcanic Basin Petroleum Research (Norway) (Norvège) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet DECEP (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Economic Sciences
Statut du projet : SIGNED

This project aims to analyse how Circular Economy (CE) transitions may affect income distribution and welfare across socio-economic groups. With global material use expected to double in 40 years, reliance on material resources for economic growth raises sustainability concerns. CE offers an alternative by promoting resource efficiency, waste reduction, and material reuse, potentially leading to more sustainable economic growth. Despite the growing importance of CE, there remains a critical gap in understanding its distributional effects, particularly its effects on economic inequality and welfare. While some economic models have been developed to assess the effectiveness of CE policies, they overlook the redistributive dimensions of these transitions. This project seeks to fill this gap by developing a Computable General Equilibrium (CGE) model that integrates both welfare and inequality analysis in the context of CE policies. Building on the work of two string of literature: 1) on CGE modeling which investigate redistributive polices and 2) on CGE modeling of the CE, this project will apply state-of-the-art CGE modeling to assess how CE transitions may affect socio-economic groups. It will explore dynamic scenarios of policy interventions, measuring the effects on income distribution, resource use, and overall welfare. The project's objectives include developing a comprehensive CGE model to analyze CE's effects on redistribution, calibrating the model using relevant economic data, and providing policymakers with actionable insights on how to design equitable and efficient CE policies. Ultimately, this project will provide insights into designing policies that balance socio-economic objectives with environmental sustainability. It will contribute to a deeper understanding of how to ensure that the shift towards a CE is not only resource efficient but also socially equitable, minimizing the risks of increased inequality.

Mots clés : computable general equilibrium modeling income inequality welfare analysis resource efficiency circular economy sufficiency

Participants :
- Université Savoie Mont Blanc (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 300772.96 €
- Université de Tilbourg (Pays-Bas) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Zurich University of Applied Sciences (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet TSPAN14-AD (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Alzheimer’s disease (AD) is the most prevalent deadly neurodegenerative disorder for which no effective treatment exists as of today. Therefore, there is an urgent need to better understand the molecular mechanisms behind AD in order to develop more effective treatments against this complex disease. Recent genetic findings have highlighted several AD-associated genes, many of which are preferentially expressed in microglia in the brain. One of these is tetraspanin 14 (TSPAN14), whose physiological function in the brain is not yet understood. Recent studies suggest that TSPAN14 may act as a functional regulator of ADAM10, a transmembrane protease that cleaves multiple substrates in the brain including the AD-associated protein TREM2. Full-length TREM2 is essential for the phagocytic activity of microglia and its cleavage by ADAM10 results in loss of function. The central aim of the TSPAN14-AD project is to understand how TSPAN14 controls molecular pathways involved in AD, by focusing on proteolysis and function of TREM2. Specifically, we hypothesize that TSPAN14 increases AD risk by modulation of TREM2 cleavage and microglial phagocytosis. The 3 objectives of TSPAN14-AD are to: (1) determine whether AD-protective TSPAN14 alternative splicing variants result in reduced TSPAN14 protein expression; (2) elucidate whether reduced TSPAN14 expression results in decreased ADAM10 cell surface expression; (3) assess whether loss of TSPAN14 reduces TREM2 cleavage and enhances phagocytic activity of microglia. To accomplish this, a combination of biochemical, molecular, and proteomic techniques will be used within both in vitro and in vivo models, including human induced pluripotent stem cell (iPSC)-derived microglia and post-mortem human brain tissue. Outcomes of the project have the potential to fill in a large gap in our current understanding of molecular mechanisms leading to AD pathogenesis and may provide insight into novel therapeutic targets for AD and related disorders.

Mots clés : alzheimer s disease, induced pluripotent stem cells, microglia, tspan14, trem2, adam10 alpha secretase, neurodegeneration

Participants :
- Université technique de Munich (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 173847.36 €
- German Center for Neurodegenerative Diseases (Allemagne) — Partner, associated partner, Recherche, subvention : 0.0 €
Projet TRANSITION (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

The cerebral cortex with its range of specialized excitatory projection neurons is essential to the high-order cognitive functions of the brain. These hundreds of subtypes of projection neurons arise from a uniform pool of multipotent apical progenitors (APs) which sequentially generate neuronal progeny with distinct fates over time. Recent technological advances in single cell transcriptomics revealed the existence transcriptional programs that seed neuronal diversity. While this working model provides a good explanation for the developmental origin of the distinct neuronal subtypes, it is flawed by the existence of some non-correlating mRNAs and proteins. Indeed, a significant fraction of mRNA that characterizes mature neurons can already be found untranslated in progenitors. The additional mechanisms that coordinate the protein synthesis and ensure correct protein expression in progenitors and daughter neurons have not been identified yet. This project focuses on solving the timely question of which mechanisms, synergically with transcription, are required to refine gene expression during neurodevelopment and cortical patterning. To do so, we explore the role of translation and its critical adaptor molecule, the transfer RNA (tRNA), in regulating the competency of APs to generate distinct neuronal fate during mouse embryonic cortices development. We will generate a comprehensive view of tRNAs abundance and translation efficiency in APs at ages E12 to E17. This will uncover a novel regulatory role for tRNAs, updating the conventional view of them as housekeeping genes, and find new candidate genes for cortical development in both health and disease. All in all, we will provide a new working model for how neuronal fate and diversity are regulated and opens avenues for future research in other developmental fields where translation has been previously overlooked.

Mots clés : trna, cortical development, translation, apical progenitors, neuronal diversity

Participants :
- Centre européen de recherche en biologie et en médecine (France) — Coordinator, beneficiary, Recherche, subvention : 195914.88 €
Projet HELP-CARE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Supporting the mental wellbeing (MWB) of healthcare workers (HCWs) is a global public health priority with far-reaching societal and economic consequences. HCWs face multiple occupational risks that can significantly affect their mental health. The COVID-19 pandemic has exacerbated strained working conditions in hospitals, leading to increased rates of stress, depression, and burnout, particularly among women and nurses. This has resulted in a concerning shortage of HCWs, triggering a negative cycle of deteriorating working conditions, reduced job satisfaction, compromised healthcare quality, and patient safety. To address this critical issue, an intersectoral action using innovative, multi-level interventions promoting MWB is necessary. However, the lack of robust evidence of cost-effectiveness for preventive approaches in the healthcare sector hampers informed health policies and sustainable actions. Three major hindrances to progress are identified: the absence of positive mental health indicators (MWB) as the primary intervention outcome, the need for a multifaceted approach considering individual and organizational factors, and the lack of health economic evaluations. The HELP-CARE project emerges as a solution, aiming to provide a realist and economic evaluation of a multi-level MWB-based intervention in the public healthcare sector launched by the technological company HOWDY.care in Denmark. The study will use Structural Equation Modeling (SEM) and Cost-Benefit Analysis on large longitudinal data of Danish HCWs to understand how this type of intervention works and its economic impact. HELP-CARE entails a strong inter-sectoral collaboration (academic-public-private-NGO) whose findings will pave the way for more effective interventions to enhance HCWs' MWB.The involvement of leading experts in the field from the Department of Psychology at University of Copenhagen offers valuable resources and infrastructures for the success of this project and my career.

Mots clés : mental wellbeing, occupational health, healthcare workers, realist evaluation, wellbeing economics

Participants :
- Université de Copenhague (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 230774.4 €
- Mental health europe - sante mentale europe (Belgique) — Partner, associated partner, Autres, subvention : 0.0 €