Projet PROSTAMET (Horizon Europe, appel à projets 2022)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

PROSTAMET is an immersive Doctoral Network (DN), that aims to train the next generation of researchers tackling complex multifactorial diseases, including cancer, that are typically characterized by an outspoken inter- and intra-patient heterogeneity and that increasingly face our ageing society. Despite unprecedented technological advances to dissect disease into its smallest details, the translation into cost-effective and personalised treatment approaches is one of the timeliest challenges that face the scientific community and that require a specific transdisciplinary mindset and education. Focusing on prostate cancer as a key paradigm of such a complex disease and as one of European Health Union’s new focus areas for organised screening, PROSTAMET aims to bridge current gaps in translational research, capitalising on the underexplored clinical potential of altered lipid metabolism in cancer. Through a close collaboration among well-selected academic and non-academic partners with highly complementary expertise, PROSTAMET aims to set up a unique lipid-focused translational research pipeline from cutting-edge spatially-resolved molecular discovery, through validation in gold-standard models, all the way to innovative drug development. Through its modular and bidirectional nature with multiple entry points, this pipeline is expected to generate outputs at multiple levels of the drug development chain for sustainable downstream valorisation. Through a combination of high-level technological “hands-on” research, non-academic placements and courses/workshops on scientific and complementary “soft” skills facilitated by the academic/non-academic composition of the consortium, PROSTAMET’s ambition is to provide young researchers with a creative and holistic view on translational research along with strong transferable skills to prepare them to take up thriving careers in a transformative health care system focusing on personalised precision medicine.

Mots clés : lipids, lipidomic, drug development, prostate cancer, multiomics

Participants :
- Université de Toulouse (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- IRBM Science Park (Italie) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Institut de Recherche et d’Innovation en Santé de l’Université de Porto (Portugal) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- IPO Porto (Portugal) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 243403.2 €
- Université Côte d'Azur (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Dompé (Italy) (Italie) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université Clermont Auvergne (France) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 282693.6 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 282693.6 €
- Horizons unleashed ltd (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Piemonte Orientale Amedeo Avogadro (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 259437.6 €
- Université de Pérouse (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 259437.6 €
- Aspect analytics (Belgique) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Namur (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 262620.0 €
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 282693.6 €
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 525240.0 €
- Sonja noss (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €