Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet Cellinfo (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Signaling pathways are cascades of biochemical reactions that transduce environmental signals to the cell interior. The cells rely on the information transduced through signalling pathways to govern biological functions and maximise the fitness of the organism. Conversely, defects in the signalling pathways are implicated in various diseases, e.g. carcinogenesis. The intricate network of signalling pathways indicates the existence of sophisticated information processing mechanisms, motivating the key questions of this project: How much information is transmitted from the environment through the signalling pathway? How many features of the signals are conveyed? Are signals integrated over time? To answer these questions, the project combines state of the art quantitative optogenetic experiments and theoretical modelling using information theory to quantify the information flow in the canonical MAPK signaling pathway. Experimentally, a well-defined stimulus will be applied at the beginning of the pathway while measuring the response at the end of the signaling cascade. The results will be integrated into a theoretical framework based on statistical physics and information theory to quantify how much static and dynamic information is being transmitted, offering key insights into cell function — the building blocks of living organisms — with potential application in drug design. The strong interdisciplinary nature of this project and the detailed dissemination strategy promotes collaboration between research communities of physicists and biologists, as well as reinforces information as a key concept in life sciences. The included training plan ensures the candidate will acquire skills in advanced experimental and theoretical techniques, and the two-way transfer of knowledge provides mutual benefit between the candidate and the host institution.

Mots clés : erk signaling, mdck cells, optogenetics, information theory, modelling of cellular processes

Participants :
- Institut Curie (France) — Coordinator, beneficiary, Recherche, subvention : 184707.84 €
Projet LYMPHOSIGN (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Signaling through the B cell receptor (BCR) is central to the development and maintenance of B cells. In light of the numerous proliferative and survival pathways activated downstream of the BCR, it comes as no surprise that malignant B cells would co-opt this receptor to promote their own growth and survival. However, direct evidence for BCR signaling in human lymphoma has only come to light recently. In this proposal, I aim to better understand the role for antigen-dependent vs. antigen-dependent BCR signaling as a pathogenic mechanism in the progression of Follicular lymphoma (FL), a indolent lymphoid malignancy that retain BCR expression during malignant progression. Further investigating the intrinsic role of BCR might lead to the development of new therapeutic approaches based on the inhibition of the BCR pathways. Using an innovative loss-of -function RNA interference genetic screen together with an engineered in vitro system allowing to test FL patients's BCR reactivity and identify putative ligands, we will 1) determine whether BCR signalling in FL relies to "chronic active" or "tonic" signals and 2) identify the nature of antigen(s) recognized by FL's BCR that may sustain signalling; each signalling pathway offering different opportunities for therapeutic intervention. For this project, I decided to chose the Louis Staudt’s group at the National Cancer Institute (NIH) for the outgoing phase since his group has been looking for years how to target B-cell receptor signaling as a treatment strategy. The unique expertise in the state-of the art functional genomic methodologies acquired during my stay at the NCI will be crucial for setting-up new scientific projects, promote extended collaborations and strongly support my re-establishement in Europe to reach an independent position.

Mots clés : follicular lymphoma, b cell receptor, signaling pathways, rna interference genetic screen, functionnal genomics

Participants :
- Institut national de la santé et de la recherche médicale (France) — Coordinator, beneficiary, Recherche, subvention : 200119.5 €
- Government of the United States of America (Etats-Unis) — Partner, organization partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
Projet NOVEL (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Significant advances are needed to improve the speed and efficiency of future communication and computing systems. Photonic interconnect components are the only solution to offer both high speed and low power consumption. To this end, vertical-cavity surface-emitting lasers (VCSELs) have been widely deployed as optical interconnects in the last two decades. Even though the current VCSEL technology has been very successful, its processing approach has been proven to be particularly challenging for miniaturization, it reduces the reliability for small lasers and its high thermal resistance substantially degrades the lasers’ performance. This project addresses all these bottlenecks by focusing on the development of a nanoscale VCSEL (NOVEL) device for ultra-low threshold, energy efficient and ultra-fast operation for future optical interconnects and light sources. The driving idea of this proposal is based on using a lithographically defined laser concept to develop a novel growth and fabrication process for GaAs-based VCSELs. This will employ buried electrical- and optical-confinement method to provide us with a unique opportunity to scale the cavity down to 500 nm diameter to demonstrate the viability and performance of the NOVEL device. Additionally, this research proposal aims to investigate the potential of NOVEL array architectures for applications in sensing and innovative high beam quality lasers. This project is expected to have a strong impact both in academia and industry as it will open the way for great flexibility in the design of VCSELs and nanolasers with high reliability essential for commercialization of research. The NOVEL devices with their fundamentally new capabilities hold special promise in a wide range of scientific disciplines including optical communication, computer science, quantum electrodynamics, laser physics, on-chip nanophotonics and biosensing.

Mots clés : semiconductor laser, nanolaser, vcsel

Participants :
- Bilkent University (Turquie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 59192.1 €
- Bilkent University (Turquie) — Coordinator, beneficiary, Recherche, subvention : 98653.5 €
Projet K-TRIO 4 (Horizon 2020, appel à projets 2020)
Action : European Researchers' Night
Statut du projet : CLOSED

Since 2006, members of EURAXESS Bulgaria have organised 12 European Researchers Nights (ERN), and have attracted several new consortium members with different profiles – universities, research institutes, NGOs, entrepreneurs. Based on past experience, the main goal of Researchers in the Knowledge Triangle (K-TRIO 4) project is to bring researchers closer to society, attract young people to STEM and boost citizens science. The project will contribute for increasing the number of researchers and innovators in Bulgaria by making the society, and young people, aware of excellent European achievements in research and innovation, and of the success of Centres of Excellence (CoE) and Centres of Competence and their contribution to the Intelligent Strategy for Smart Specialisation in Bulgaria and regional development. Aware of the need of changing stereotypes and nurturing a new culture in research and innovation, the consortium will make young people aware of the multiple career paths of researchers (incl. MSC fellows), best-practice examples of researchers achievements, and research infrastructure in Bulgaria. Special emphasis will be made on European policy and on funding for research and innovation provided by EU RTD programs and Structural Funds. With a large variety of pre-events, online activities and 2-days ERN events in many Bulgarian cities, the project will create greater understanding on how research and innovation contribute for well-being of people and sustainable development, and highlight the common European efforts for building Digital Single market, Factories of the Future, Smart Cities, and take full advantage of BIG Data and Cloud computing. With the involvement of all CoE UNITe partners, and their large network, in addition to EURAXESS Bulgaria, K-TRIO 4 will cover all Bulgarian regions. Forum Science will guide a professional science communication, and ensure greater visibility of K-TRIO 4 activities.

Mots clés : researchers career, attracting talents

Participants :
- Prof. Assen Zlatarov University (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 10500.0 €
- Medical University of Varna (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 11800.0 €
- Bulgarian Academy of Sciences (Bulgarie) — Partner, beneficiary, Recherche, subvention : 13500.0 €
- Sdruzhenie forum nauka (Bulgarie) — Partner, beneficiary, Autres, subvention : 17000.0 €
- Club Young Scientists (Bulgarie) — Partner, beneficiary, Autres, subvention : 7500.0 €
- Sofia University (Bulgarie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 18000.0 €
- Trakia University (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 11800.0 €
- Tsentar po rastitelna sistemna biologiya i biotehnogiya (Bulgarie) — Partner, beneficiary, Recherche, subvention : 13000.0 €
- Angel Kanchev University of Ruse (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 11000.0 €
Projet K-TRIO 5 (Horizon 2020, appel à projets 2020)
Action : European Researchers' Night
Statut du projet : CLOSED

Since 2006, members of EURAXESS Bulgaria have organized 13 European Researchers Nights (ERN), and have attracted several new consortium members with different profiles - universities, research institutes, NGOs, entrepreneurs. Based on past experience, the main goal of Researchers in the Knowledge Triangle (K-TRIO 5) project is to bring researchers closer to society, attract young people to STEM and boost Citizens Science. The project will contribute for increasing the number of researchers in Bulgaria by making the society, and young people, aware of excellent European achievements in research and innovation (R&I), and of the Centers of Excellence (CoE) and Centers of Competence and their contribution to green, smart and sustainable regional development. In 2020 the consortium made several steps for changing stereotypes and nurturing a new culture in R&I, and making young people aware of the multiple career paths of researchers (incl. MSC fellows), best-practice examples of researchers achievements, and research infrastructure in Bulgaria. Special emphasis will be made on European policy and on funding for R&I provided by EU RTD programs and Structural Funds. With a large variety of pre-events, online activities and 2-days ERN events in many Bulgarian cities, the project will create greater understanding on how R&I contribute to well-being of people and sustainable development, and highlight the common European efforts for Green and Digital transformation, building Smart Cities, and taking full advantage of BIG Data, Artificial Intelligence and Cloud computing. With the involvement of all CoE UNITe partners, and their large network, in addition to EURAXESS Bulgaria, K-TRIO 5 will cover all Bulgarian regions. Forum Science will guide a professional science communication, and ensure greater visibility of project activities.

Mots clés : researchers career, attracting talents

Participants :
- Sdruzhenie forum nauka (Bulgarie) — Partner, beneficiary, Autres, subvention : 18500.0 €
- Club Young Scientists (Bulgarie) — Partner, beneficiary, Autres, subvention : 7900.0 €
- Sofia University (Bulgarie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 20000.0 €
- Trakia University (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 13000.0 €
- Angel Kanchev University of Ruse (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 13500.0 €
- Bulgarian Academy of Sciences (Bulgarie) — Partner, beneficiary, Recherche, subvention : 11000.0 €
- Tsentar po rastitelna sistemna biologiya i biotehnogiya (Bulgarie) — Partner, beneficiary, Recherche, subvention : 16000.0 €
- Regionalen istorichen muzei sofiya (Bulgarie) — Partner, beneficiary, Recherche, subvention : 7200.0 €
- Prof. Assen Zlatarov University (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 10500.0 €
Projet NPA (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Since the 1990s, Educational Neuroscience has become an emerging field of research which studies cognitive brain functions (thinking, memory, attention, emotions) and interfaces with the educational environment with the aim of improving teaching and learning. Simultaneously, "Drama Teaching", a teaching methodology based on performing arts introduced in the 1970s, is now generating interest, especially in Foreign Language Learning. This research project will investigate aspects of cognition involved in the language learning process and it will analyse how Drama Teaching dynamics can impact language learning and proficiency. In order to define Drama Teaching as a methodology which involves the brain-mind-body dimension and fosters development of the learner as a whole person, a cognitive perspective will be adopted in relation to issues of a) embodied cognition, b) role of emotions in learning, c) impact of context and experience on learning d) cross-cultural identity process, development and awareness. Theoretical scientific investigation will be conducted on cognitive aspects relevant to learning, followed by the study and observation of dramatization practices. Development of curriculum and course implementation will follow. Particular attention will be given to the assessment of learning results and proficiency levels, as well as to the cognitive and emotional factors. The inter-disciplinary perspective adopted by this study is aimed at contributing to the debate on creative, interactive Foreign Language Education taking place in Europe and in the world. The scope is to contribute to the multi-disciplinary inquiries of Educational Neuroscience by elaborating a neuroscientifically grounded theory of Drama Teaching which gives educators guidelines to expand the range of teaching possibilities in accordance with the principles of Learning/Teaching of the “Common European Framework of Reference for Languages”.

Mots clés : process drama, drama teaching, cognitive neuroscience, neuroscience of learning, second language acquisition, applied linguistics, neuroeducation, neurodidactics

Participants :
- University of Sydney (Australie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Ca' Foscari University of Venice (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 250518.6 €
Projet VOLTAIC (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Since the 2010 Eyjafjallajökull eruption in Iceland, which evidenced the fragility and vulnerability of our globalized society to disastrous socio-economic impacts of volcanoes, ash monitoring has become a priority of the European Commission. In this scope, lightning, observed in numerous eruptions, and easily detectable in all weather conditions, is proving strong potential as a novel monitoring tool of ash plumes. Although thunderstorm lightning have been studied for decades, little is known on the mechanisms of ash particles charging and how discharges occur in explosive eruptions, thus preventing to link lightning occurrence with ash plume characteristics. The aim of this project is hence to combine laboratory and field studies to advance our knowledge of electrical properties of ash plumes. I will take advantage of a unique experimental setup developed at LMU-Munich to bridge the gap between physical theory and field observations. Generating volcanic lightning in the lab under constrained conditions, and comparing them with field observations, I will derive quantitative relationships between the plume characteristics (temperature, velocity, and ash concentration), the charging and the segregation of ash particles, and the occurrence of electrical discharges. Two field campaigns are planned for this scope at the permanently active Sakurajima volcano (Japan), where volcanic lightning is frequently observed. High-speed visible-light cameras will be used to measure lightning while a thermal camera will unravel the plume structure and dynamics. In the scope of a secondment at Hamburg University, I will use a numerical model to simulate the plume microphysics and will implement image-processing methods to build the first complete database coupling plume and lightning characteristics. Through this project we aim at the first quantitative interpretation of volcanic lightning with the scope of keeping Europe at the forefront of volcano research and hazard mitigation.

Mots clés : explosive volcanism, volcanic plumes, lightening, shock tube experiments

Participants :
- Ludwig-Maximilians-Universität München (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 171460.8 €
Projet REFINTEG (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Since the Syrian civil war began in March 2011, the United Nations High Commissioner for Refugees estimates that more than 13 million people are in need and an estimated 5.6 million Syrians have fled the country. From this group of Syrian refugees, around one million have requested asylum in different countries of the European Union. While in the EU there is a strong debate concerning the recent refugee crisis and the need to completely reform the current asylum system, in Canada the resettlement and integration of refugees has been a considerable success through the implementation of the Private Sponsorship of Refugees Program which has received much attention from policy-makers in other countries over the past decades. The Overall Objective of this project proposal is a comprehensive analyze of the Canadian private sponsorship model to integrate refugees, of its impact in providing to Syrian refugees a safe and legal way to resettlement and socio-economic integration, and an exploration of its possible modalities of application in some countries of the European Union. The researcher will firstly analyze and present, based on a comprehensive review of government documents, existing academic literature and available data, the overall program, and it will describe its benefits, general results and challenges. Subsequently, the researcher will analyze the private sponsorship program impact in the case of Syrian refugees and will compare the outcomes of this model with the outcomes of other programs such as federal government support and Blended Visa Office-Referred (BVOR) program. Then, the researcher will explore the possible application of the Canadian model in some specific EU countries such as Italy and Germany, identifying and discussing possible benefits and challenges, and comparing the results obtained by policies already implemented by these countries with the results of the Canadian model.

Mots clés : multiculturalism, interculturalism, intercultural dialogue, human rights

Participants :
- University of Genoa (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 255768.0 €
- Université du Québec (Canada) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet DisaMob (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Since the end of apartheid, the role of racial categories in the reproduction of inequalities appears to have decreased in South Africa but, the extent of these changes remains debated. This project aims to renew our understanding of these processes by adopting a transversal approach to understanding post-apartheid society. To do so, I will attend to the life trajectories of people who live with a physical disability: a departure point that will allow me to engage with individuals from various racial and class backgrounds. As a counterpoint to statistical surveys on social mobility and to the Marxist tradition of social class in South Africa, I will draw on Bourdieu’s multidimensional analysis of the social space to articulate the impacts of racial and social categories, but also of disability and gender, on professional careers. I will also question how expectations and claims for support impact on disabled people’s careers, based on an analysis of social configurations as forms of interdependency that have ambiguous effects on disabled people’s professional trajectories. For instance, could the delegation of care to women explain why women with disabilities find work less easily than their male peers? Therefore, this project also aims to integrate the issue of disability within the study of social mobility. The outgoing phase at the University of Johannesburg will help me foster my knowledge on current social sciences debates in this country, extend my network with local researchers and conduct ethnographic research (60–80 biographical interviews with disabled people and 6–9 study cases of social configurations based on observation and interviews). In return, the acquired knowledge and the research results will serve as a comparison point during the incoming phase for research undertaken at the University of Liège around work, dynamics of inequalities, and health policies in other parts of Africa.

Mots clés : south africa, disability

Participants :
- University of Johannesburg (Afrique du Sud) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Liège (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191856.96 €