Projet ELBA (Horizon 2020, appel à projets 2017)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : CLOSED

Liquid biopsies have been heralded as a game changer in cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complimentary approach for tissue biopsies. Blood represents a rich source of information through which solid cancers (and their subtypes) can be detected, identified and classified, and matched to a specific therapy. However, despite the potential of individual approaches, the promise of liquid biopsies has not yet materialised in the clinic. Widespread deployment requires creative next-generation researchers with an innovative mindset with access to a unique toolbox, including medical know-how, molecular diagnostics expertise (from health economics to regulatory), and statistical/bioinformatical proficiency. Currently, there are no comprehensive training programmes to address this need. To move the promising liquid biopsy technology out of its infancy, the research programme and educational curriculum of the European Liquid Biopsy Academy (ELBA) will cover the entire value chain of diagnostics development and integrate all required disciplines and sectors. ELBA will educate 15 Early Stage Researchers (ESRs) with the skills to circumvent the obstacles currently hampering effective development and commercialisation of liquid biopsy approaches. By creating a sustainable network to foster long-term multidisciplinary relationships and communication networks with various stakeholders we aim to accelerate clinical translation of these blood-based diagnostics. Most importantly, we have designed a well-balanced training programme to provide excellent career opportunities for the 15 ELBA ESRs. this includes training on state-of-the-art technologies and tools; bioinformatics, biostatistics and mathematical modelling; health economics and health technology assessment; diagnostic test development (including intellectual property and regulatory affairs); transferable skills (including leadership) and patient inclusion.

Mots clés : cancer, liquid biopsies, tumour educated platelets, circulating tumour dna, extracellular vesicles, exosomes, circulating tumour cells

Participants :
- Universität Hamburg (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 498432.96 €
- Amsterdam University Medical Centers (Pays-Bas) — Coordinator, beneficiary, Recherche, subvention : 510748.56 €
- Genomescan b.v. (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Izon science limited (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Padua (Italie) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- V.o. patents & trademarks (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- CERCA Institution (Espagne) — Partner, beneficiary, Recherche, subvention : 495745.92 €
- Pangaea biotech sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 247872.96 €
- Exosomics siena spa (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 258061.32 €
- European cancer patient coalition (Belgique) — Partner, organization partner, Autres, subvention : 0.0 €
- Centre Hospitalier Universitaire de Montpellier (France) — Partner, beneficiary, Recherche, subvention : 525751.2 €
- University of Granada (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 495745.92 €
- Plovdiv University (Bulgarie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 218651.4 €
- Tataa Biocenter (Sweden) (Suède) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Harvard University (Etats-Unis) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Ttopstart bv (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Sense about Science (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- GILUPI (Germany) (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Twente (Pays-Bas) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Factory-cro bv (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Champalimaud Foundation (Portugal) — Partner, beneficiary, Recherche, subvention : 476712.72 €