Projet RenalToolBox (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

The RenalToolBox ITN comprises a team of world-leading clinicians, scientists and industrialists from academia and private enterprise whose common goal is to develop innovative medical devices and imaging technologies to expedite the translation of cell-based regenerative medicine therapies (RMTs) to the clinic. The target disease for RenalToolBox is kidney disease, the incidence of which is increasing annually. The ITN provides an excellent framework for training 15 early stage researchers (ESRs) in a range of technological, entrepreneurial and transferable skills that will not only enhance their career prospects, but will also boost European scientific excellence and business innovation. By the end of the programme, the ESRs will have benefitted from a comprehensive multidisciplinary and multi-sectoral training experience that will equip them to expedite progress in the emerging supradisciplinary fields of biomedical devices, bio-imaging, cellular therapeutics and regenerative medicine. The research training objectives are as follows: 1. Train the young researchers in the development of diagnostic devices and novel tracers for monitoring renal function. 2. Apply cutting-edge imaging technologies to evaluate the safety and efficacy of novel cell-based RMTs in a rodent model of kidney disease. 3. Assess the safety and efficacy of different sources of mesenchymal stromal cells and explore the mechanisms whereby these cells can ameliorate kidney disease. This comprehensive training programme will endow the young researchers with the necessary scientific and industrial skills to ensure their employability and readiness to engage and lead the next European generation of scientists-entrepreneurs.

Mots clés : kidney disease, mesenchymal stem cells, multimodal imaging, mathematical tools for image analysis, near infrared dyes, cell tracking nanoparticles, preclinical models, safety and efficacy

Participants :
- University of Turin (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 261499.68 €
- Danaher (Germany) (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Nierstichting (Pays-Bas) — Partner, organization partner, Autres, subvention : 0.0 €
- Kidney Research UK (Royaume-Uni) — Partner, organization partner, Recherche, subvention : 0.0 €
- National University of Ireland (Irlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 274684.32 €
- Cyanagen srl (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 261499.68 €
- Leiden University Medical Center (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 265619.88 €
- KU Leuven (Belgique) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Utrecht University (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 531239.76 €
- Heidelberg University (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 1011153.6 €
- Ticeba gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- iThera Medical (Germany) (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 252788.4 €
- University of Malaya (Malaisie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Liverpool (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 909517.68 €
- NHS Blood and Transplant (Royaume-Uni) — Partner, beneficiary, Recherche, subvention : 303172.56 €