Projet MUSIQ (Horizon 2020, appel à projets 2018)
Action : Doctoral Networks
Panel : Physics
Statut du projet : SIGNED

In the quest to decipher the chain of life from molecules to cells, the biophysical questions being asked increasingly demand techniques that are capable of identifying specific biomolecules in their native environment at the smallest possible scale, and measuring their interactions quantitatively without perturbing the system under observation. Laser-based optical microscopy is a key technology to drive this progress in the 21st century. Still, many challenges remain in particular toward i) achieving imaging with biomolecular specificity without the artefacts from sample staining, ii) quantitative imaging, and iii) single molecule sensitivity. Progress toward biomolecular specificity at very high temporal resolution has been brought by the development of ultrafast two-dimensional electronic spectroscopy, able to address the importance of quantum coherences with the potential to unravel the fundamental machinery of Nature. Yet, measuring quantum phenomena with an optical microscope is technically challenging, and far from real-world biological applications. MUSIQ is designed as an innovative research and training network, where we will recruit 15 Early Stage Researchers to work toward the central ambitious goal of developing the next-generation optical microscopy exploiting quantum coherent nonlinear phenomena. The network brings together a unique team of 7 world-leading academics and 6 high tech companies at the forefront of optical microscopy and ultrafast laser technology developments merged with fundamental understanding of coherent light-matter interaction phenomena, development of quantitative image analysis tools, and biomedical/pharmaceutical real-world applications. MUSIQ will establish an intersectoral training and research programme at the physics/chemistry/life science interface with partners from 9 European countries, aimed at creating the next generation of skilled well-connected scientists that will pioneer the ‘quantum microscopes of tomorrow’.

Mots clés : optical microscopy, nonlinear optics, ultrafast spectroscopy, biophotonics, nanophotonics, coherent light matter interaction, vibrational microscopy, plasmonics

Participants :
- University of Modena and Reggio Emilia (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 261499.68 €
- Ape angewandte physik und elektronik gmbh (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Hertz broertjes brigitte (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Venteon laser technologies gmbh (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Light conversion, uab (Lituanie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 223947.0 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 549604.08 €
- Scientific volume imaging bv (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Politecnico di Milano (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 522999.36 €
- Institute of Photonic Sciences (Espagne) — Partner, beneficiary, Recherche, subvention : 501809.76 €
- Accelopment (Switzerland) (Suisse) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Luxembourg (Luxembourg) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 256320.0 €
- University of Konstanz (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 505576.8 €
- Cardiff University (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 909517.68 €
- GlaxoSmithKline (United Kingdom) (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 303172.56 €
- Danaher (Germany) (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Science made simple (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €