Projet TIN-ACT (Horizon 2020, appel à projets 2017)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : CLOSED

Tinnitus (“ringing in the ears”) is a very common and potentially devastating condition. People with tinnitus, continuously hear a penetrating phantom sound in absence of actual sound. An estimated 50.8 million EU citizens hear tinnitus, of which 5.1 million are severely bothered by it. Tinnitus can totally disrupt normal societal participation. Hence, tinnitus leads to enormous societal costs (€140 billion per year in Europa), mainly due to loss of productivity. Since tinnitus primary occurs at advanced age (>50 years), it is a severe challenge to the European ambition to continued inclusion of the aging population in the work force. To date, the research into tinnitus has progressed almost nowhere in the development of effective and reliable treatments for tinnitus. The applicants of the current proposal are convinced that in order to cure tinnitus, we need researchers that can bridge the gap between basic fundamental research, applied clinical research and product development. The major aim of the proposal is to train 15 future scientists who understand how basic neural mechanisms of tinnitus can be studied in animal models and human tinnitus patients, and how complementary research techniques can be used towards curing tinnitus. The central hypothesis of TIN-ACT is that reduced peripheral auditory input (via hearing loss) causes pathological changes centrally in the brain that manifest as the perception of tinnitus. In a balanced consortium, the research is organized in three scientific work packages that study how these pathological changes can be assessed, what causes them, and how they can be treated. A comprehensive training program provides specialized training by research, complementary skills and soft skills (including entrepreneurship). We will train 15 early stage researchers (ESRs) towards an excellent understanding of tinnitus assessment, causes and treatments, and with job perspectives both in the academic and non-academic sectors.

Mots clés : tinnitus, phantom perception, assessment, mechanisms, treatments

Participants :
- Hertz broertjes brigitte (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- European federation of tinnitus-associations (euti) e.v. (Allemagne) — Partner, organization partner, Autres, subvention : 0.0 €
- Universitätsklinikum Erlangen (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 498432.96 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 788626.8 €
- Siemens (Netherlands) (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Nottingham (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 546575.76 €
- Widex (Denmark) (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 290081.88 €
- Cochlear (Australia) (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 250560.0 €
- Charité - Universitätsmedizin Berlin (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 498432.96 €
- Eurogrant gmbh (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Technical University of Denmark (Danemark) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Oticon (Denmark) (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 290081.88 €
- Tinnitus hub ltd (Royaume-Uni) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- European federation of hard of hearing people (Pays-Bas) — Partner, organization partner, Autres, subvention : 0.0 €
- University Medical Center Groningen (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 766122.84 €