Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet EPFL Fellows (Horizon 2020, appel à projets 2014)
Action : Cofund Postdoctoral programme
Statut du projet : CLOSED

EPFL Fellows aims to attract experienced researchers of any nationality to EPFL - one of the leading European institutions of science and technology - to provide them with state-of-the art conditions for research in a top-class academic environment, to develop their leadership potential and to position them for success as future research leaders through an intensive training. EPFL Fellows is a relatively new programme; it started in 2013 with the support of the EU MCA-COFUND (FP7). Fellowships may be requested in any scientific discipline and run for a period of 24 months. In the context of this new COFUND proposal several new elements are introduced in EPFL Fellows to fine-tune the programme and align it with the principles set out by the EU for human resources development in Research and Innovation: i) the number of fellowships to be awarded is increased from 24 to 48; an appropriate increase in view of demand, of what EPFL can offer, and of the high selectivity of fellowships currently awarded, ii) fellows are asked to show elements of interdisciplinarity and cross-sectorial mobility in their research projects and are encouraged to carry out secondments in industry or different scientific environments, iii) employment conditions are improved by giving fellows access to Dual Career measures, iv) fellows are expected to actively participate in outreach activities, v) tangible measures are offered to facilitate transfer of technology to the market place through access to EPFL’s Tech Transfer Office and Innovation Square, vi) adaptations are made in the selection procedure to align it with the MSCA IF process and to externalize the evaluation of the proposals to the fullest extent possible while ensuring that the final decision-making process is managed in-house and hence under control. This proposal will take the “EPFL Fellows” postdoctoral fellowship programme to its next level, and open the doors of EPFL and Europe to two new cohorts of 24 promising scientists.

Mots clés : postdoctoral fellowship, incoming, re integration

Participants :
- Board of the Swiss Federal Institutes of Technology (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 3398400.0 €
Projet EPFLeaders4impact (Horizon 2020, appel à projets 2020)
Action : Cofund Postdoctoral programme
Statut du projet : SIGNED

EPFL is one of the most dynamic university campuses in Europe and ranks among the top 20 universities worldwide. Its mission is to provide first-rate education, foster pioneering research, and promote cutting-edge technological innovation.As one of the world’s top technical universities and as a leading actor driving disruptive innovation in Switzerland and beyond, EPFL is playing a critical role in the transition towards a sustainable society. Such transition requires not only new knowledge and technology but also responsible scientific leaders with an ability to think across boundaries, to envision all-encompassing solutions to critical societal problems, and to communicate their research to policymakers. EPFL has been integrating sustainability into the training of Bachelor, Master, and PhD students. The EPFLinnovators4impact programme will go one step further by integrating sustainable innovation into the training of postdoctoral researchers who wish to be part of the next generation of sustainable science leaders. Given that the majority of PhD holders eventually choose to pursue another career path than academia, it is crucial to build their entrepreneurial and leadership skills and to focus on sustainable entrepreneurship for those who have developed the required skills and knowledge to address global sustainability challenges during their PhDs. EPFLinnovators4impact is is intended for experienced researchers who have the ambition and the potential to provide innovative solutions addressing one or several of the United Nations Sustainable Development Goals. This innovative programme will provide postdoctoral fellows with funding, training, lab facilities, and expert advice allowing them to develop a novel and impactful product or service. In the course of the programme, they will be able to evaluate the potential for the commercialization of this product or service before founding a startup or licensing intellectual property to an existing company.

Mots clés : postdoctoral fellowship, sdgs, impact, innovation, entrepreneurship, startups, technology transfer, training

Participants :
- Board of the Swiss Federal Institutes of Technology (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 4413600.0 €
Projet TVPIPD (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Each year over two million babies are born very preterm (VP; <32 weeks’ gestational age) and/or with very low birthweight (VLBW; <1500g) worldwide. Despite improved neonatal care, these children remain at high risk for developmental problems later in life. The most common adverse outcomes are social, emotional and attention problems which can impact on a child’s lifelong health and wellbeing. It is therefore critical to understand trajectories of social, emotional and attention problems after VP/VLBW birth to target intervention and improve outcomes across the lifespan. However, although a wealth of data has been collected, there is a paucity of research investigating trajectories of social, emotional and attention development in this population. This project will utilise data from 28 international birth cohort studies, comprising data from an unrivalled sample of 7,053 VP/VLBW participants, the investigators of which have already agreed to data sharing. Novel, innovative statistical techniques will be applied to harmonise different measures of social, emotional and attention problems producing a unique dataset that will allow me to use complex multilevel and longitudinal growth modelling to analyse trajectories from birth to adolescence. The results will advance theoretical understanding of the developmental pathways to social, emotional and attention problems and will have international impact informing the development of clinical guidelines for follow-up care, multidisciplinary intervention, parental counselling and educational policy and planning. The ultimate aim of my proposed research is to improve lifelong outcomes for the growing population of children born very preterm. The training and experience I will gain from working with leading multidisciplinary teams in this field of research will provide me with a unique opportunity to develop myself as an independent academic with the skills, collaborations and expertise needed to become a future research leader.

Mots clés : sequelae of preterm birth, neurodevelopmental disorders, trajectories of social, emotional and attention problems, risk factors, international cohort studies, individual participant data meta analysis

Participants :
- University of Tennessee System (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Leicester (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 271732.11 €
- Monash University (Australie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet CPFC (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Earth’s climate is rapidly changing, with major socioeconomic consequences. A key scientific challenge is to improve climate-model projections by reducing uncertainty in cloud-climate feedbacks. The proposed research will investigate a cloud-feedback mechanism that has a potentially powerful but highly uncertain effect on global climate change. The feedback involves a conversion of ice cloud to liquid cloud that is caused by a warming atmosphere. Our goal is to attain the first quantitative estimate of this feedback based on satellite observations and to develop climate-model software that enables a direct model-to-observation comparison of the feedback. This will close gaps between observational and modeling studies of cloud feedbacks, and it will provide a clear benchmark for assessing climate projections. This fellowship will be carried out in the Department of Geosciences at the University of Oslo under the supervision of Prof. Trude Storelvmo. The research will leverage my expertise in satellite observations and that of the host in climate modeling, thus facilitating a two-way transfer of knowledge. I will gain several new experiences during the fellowship, including working in an interdisciplinary research group, studying in Europe, co-advising graduate students, and engaging with different outlets for public communication. The skills, knowledge, and international network that I will develop will put me in an excellent position to achieve my long-term goal of leading a research group.

Mots clés : cloud climate feedbacks, mixed phase clouds, climate sensitivity, global climate modeling, radiative transfer

Participants :
- University of Oslo (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 214158.72 €
Projet EcoSF (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

EcoSF investigates the prominence and distinctive representation of ecological issues in Italian science fiction (1952-2019). The project, which provides one of the very first extensive academic studies dedicated to this genre in Italy, examines the debate surrounding its cultural status and traces its evolution in relation to Italian history and culture. An ecocritical perspective is adopted, interrogating the relationship between literary imagination and the environment. Through such approach, EcoSF shows how literature is important to generate awareness of ecological issues and explore literary responses to the current ecological crisis. The cognitive estrangement raised by the imaginative effort of science fiction is central to the necessary re-thinking of current cultural and epistemological paradigms based on anthropocentrism, human exceptionalism, and ecophobia. Furthermore, by interrogating our current relationship with the environment, and imagining known environments after ecological catastrophes, science fiction can provide a tool to investigate our cultural heritage. Combining the innovative critical tools of ecocriticism and the speculative imagination of science fiction, EcoSF offers an alternative genealogy of our understanding of the environment outside an ecophobic perspective. The dissemination of the research will adapt dystopian imagination to the case of Venice, thus employing the theoretical categories of the project to reflect on local communities and landscapes.

Mots clés : science fiction, italian literature, environmental humanities, ecocriticism, ecology

Participants :
- University of North Carolina System (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Padua (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 251002.56 €
Projet EDUHEALTH (Horizon 2020, appel à projets 2016)
Action : Staff Exchanges
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Educating for Equitable Health Outcomes - the Promise of School Health and Physical Education (EDUHEALTH) is a collaborative research project that will build on an existing working relationship and create long-lasting networks between three universities in Sweden, Norway and New Zealand. The project’s primary goal is to make a meaningful contribution to the European Union (EU) strategy to promote physical activity and health for all citizens. The World Health Organisation (WHO) states that everybody has the right to attain ‘health’ and advocates ‘equal health’ for all citizens of all nations. As researchers of Physical Education Teacher Education (PETE) and Health and Physical Education (HPE) we recognise that HPE plays a crucial role in attaining this goal. However, the way HPE is taught and conceptualised does not always provide equitable health outcomes across gender, sexuality, ethnicity, religion and social class. The EDUHEALTH project aims to contribute to improved individual and societal health by examining the role that school HPE can play in contributing to equitable health outcomes for the people of the EU and beyond. Our common understanding and experiences of working with socially-critical perspectives in PETE draws us together and provides a shared belief that health equity goals could be more effectively reached when socially-critical perspectives are at the core of HPE pedagogy. EDUHEALTH aims to share knowledge and study HPE teachers practices from a ‘bottom-up’ perspective by observing in schools. More specifically, by drawing on a Critical Incident Technique (CIT) methodology we will identity effective/productive socially-critical HPE teaching practices. These practices will be used to develop intervention strategies that are intended to assist teachers in other HPE contexts to further refine and develop their practices to become more inclusive and engaging thus helping contribute to healthier citizens and societies.

Mots clés : health, physical activity, equity, social justice, physical education, teacher education, critical incident technique

Participants :
- Linnaeus University (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 45000.0 €
- Inland Norway University of Applied Sciences (Norvège) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 22500.0 €
- University of Auckland (Nouvelle-Zélande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet ElectroPheX (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Chemistry
Statut du projet : SIGNED

ElectroPheX aims to develop electrochemically-mediated methods for the site-selective halogenation of phenols. Electrochemistry will be the main feature of this project as it can be an efficient way to access and manipulate reactive intermediates. The project will span disciplines (interdisciplinarity) and aims to study electrochemistry’s ability to act as an enhancement tool for both selectivity and reactivity. Electrochemistry will help us to: (1) help us study the redox properties of catalysts, compounds, complexes and substrates (find redox potentials etc.); (2) to generate open-shell species; and, (3) to adjust the oxidation state of metals. WP1-ORTHO focuses on (1) the design and synthesis of a series of compounds that contain N-halogen bond and they are capable of facilitating the ortho-halogenation of phenols upon anodic oxidation, (2) the study of intermolecular interactions and how the electrochemical generation of the corresponding radical-cation of N-halogen bond will alter/enhance the strength of the former. WP2-META aims at the development of an electrochemically-mediated methodology for the meta-halogenation of phenols. Early transition metals (Mn, Co) will be used in order to facilitate the desired transformation. Electrochemistry will orchestrate the whole procedure giving access to adjacent oxidation states of metallic centers. WP3-PARA targets para-halogenation of phenols mediated by a novel catalyst that mimics a main feature of photosystem II leading to a proton-coupled electron transfer (PCET) protocol for the transformation. In WP4 the acquired knowledge will be translated to complex phenolic compounds in order to achieve a late-stage functionalization. SAR libraries, PET radiotracer, Also, the synthesis of highly site-selective halogenation of phenols can provide valuable intermediates for the preparation of poly-substituted arenes with a well-defined relationship between their substituent via cross-coupling reactions.

Mots clés : electrochemical mediated reactions

Participants :
- Scripps Research Institute (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Max Planck Society (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 246669.12 €
Projet EM-PRIOR (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Electron cryo-microscopy (cryo-EM) is the fastest growing technique to explore the structure of biological macromolecules. To limit radiation damage, images are recorded under low-dose conditions, which leads to high levels of experimental noise. To reduce the noise, one averages over many images, but this requires alignment and classification algorithms that are robust to the high levels of noise. When signal-to-noise ratios drop, cryo-EM 3D reconstruction algorithms become susceptible to overfitting, ultimately limiting their applicability. The algorithms can be improved by incorporating prior knowledge. The most widely used approaches in the field to date incorporate the prior knowledge that cryo-EM reconstructions are smooth in a Bayesian approach. However, in terms of information content, the smoothness prior reflects poorly compared to the vast amount of prior knowledge that structural biology has gathered in the past 50 years. I aim to develop a computational pipeline that can exploit much more of the existing knowledge about biological structures in the cryo-EM structure determination process. I will express this prior knowledge through convolutional neural networks that have been trained on many reconstructions, and use these networks in novel algorithms that optimise a regularised likelihood function. Similar approaches have excelled in image denoising and reconstruction in related areas. Preliminary results with simulated data suggest that significant improvements beyond the existing methods are possible, both in computational speed and in signal recovery capabilities. The proposed methods will enable faster computations with less user involvement, but most importantly, they will extend the applicability of cryo-EM structure determination to many more samples, alleviating the existing experimental requirements of particle size, ice thickness and sample purity.

Mots clés : cryo em, relion, regularization, inverse problems, denoising, adversarial regularizers

Participants :
- UK Research and Innovation (Royaume-Uni) — Coordinator, beneficiary, Recherche, subvention : 224933.76 €
Projet ExplicitDarmonProg (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : CLOSED

Elliptic curves are the heart of contemporary research in number theory. For example, their modularity played a crucial role in Wiles' proof of Fermat's Last Theorem. Understanding their rational points is the subject of the Birch and Swinnerton-Dyer Conjecture (BSD), one of the seven $1M Clay Mathematics Institute Millennium Prizes. This proposal is concerned with rational points on elliptic curves and linked to both BSD and modularity. The Darmon Programme is an ambitious project initiated by Henri Darmon, aiming to provide constructions of points on elliptic curves over number fields, and to prove new cases of BSD. The proposed action is an initiative to extend the Darmon Programme, make known constructions explicit and algorithmic to provide extensive data that will be invaluable to researchers in the field, and guide further theoretical work. Warwick has one of the largest and most active explicit number theory groups in the world, consisting of 2 professors, 3 lecturers, 8 research fellows and 12 PhD students, making it a natural host for the project. The supervisor Siksek, is a leading expert on elliptic curves, rational points and modularity, with considerable experience in supervising research including 5 Marie Curie fellows. Masdeu did his undergraduate studies in Barcelona. He completed his PhD (McGill) under the supervision of Darmon, and therefore has intimate understanding of the Darmon Programme. Masdeu then worked as Ritt Assistant Professor at Columbia University before joining Warwick as a postdoc in 2014. Therefore his research experience has almost entirely been confined to North America, even though his ambition is to establish himself as an independent researcher at a prestigious European university. Masdeu has substantial research results with 8 papers accepted in strong journals. This project will integrate him into the European research environment, and give him new skills and research directions to enable him to realize his goal.

Mots clés : modular symbols, modularity, shimura curves, stark heegner points, darmon points

Participants :
- University of Warwick (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet 5HT-DREADD (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Emotional health and well-being is widely accepted to be crucial for healthy life and the success of societies. Anxiety and depression are two common and debilitating emotional disorders, with highly negative social and financial implications. Serotonin (5-hydroxytryptamine; 5-HT) is thought to be critical to the healthy mood regulation and strongly implicated in the vulnerability to anxiety and depression. Importantly, accumulating evidence suggests that 5-HT’s main influence is upon emotional learning rather than on mood directly. The objective of this proposal is to determine the neural mechanisms through which changes in 5-HT levels, within defined neuronal circuits, affect learning and memory for aversive emotional experiences. New pharmacogenetic techniques will be developed that allow the selective triggering of 5-HT neuron activation and then inhibition in the same animal. We will use this technology to stimulate or inhibit 5-HT release in the basolateral amygdala, a brain area that is crucial for aversive learning, whilst an animal is engaged in an emotional processing task. Through this we will learn how 5-HT modulates neuronal activity in the amygdala at critical time-points during the encoding and retrieval of aversive memories. The results from these studies will provide entirely new insights into how 5-HT modulates amygdala information processing and aversive learning. Understanding how 5-HT affects emotional learning will ultimately lead to a deeper understanding of healthy mood states and the biological mechanisms underlying vulnerability to disorders such as anxiety and depression.

Mots clés : dreadds, kord, anxiety

Participants :
- University of Oxford (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €