Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet GENEVABREED (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : TERMINATED

Apple scab caused by Venturia inaequalis is the major constraint to apple production worldwide, causing severe economic losses. As current commercial cultivars are highly susceptible to scab, introduction of new scab-resistant cultivars will reduce the intensive use of pesticides now required to control this disease. Although the ‘Geneva’ apple is an important source of resistance for breeding, its complex scab resistance has not been properly characterized. In preliminary studies, we mapped to chromosome 4 of ‘Geneva’ a 5 cM region containing three genes conferring both dominant and recessive scab resistance, which corresponds to a 2 Mbp region containing nine candidate NBS-LRR resistance genes on the physical map of ‘Golden Delicious’ (GD). This provided the first evidence of recessive genetic control of apple scab resistance. In this project proposal, we will further characterize this complex locus, employing next generation sequencing, together with bioinformatics and functional analysis of disease candidate resistance genes (CRGs): (1) we will sequence the resistance locus in ‘Geneva’ and identify CRGs that are polymorphic (presence/absence, or sequence polymorphism) between the resistant ‘Geneva’ and the susceptible GD; (2) we will clone each CRG with its native promoter, terminator and introns; and (3) transform susceptible lines with the individual CRGs to evaluate their effect on the level of disease resistance and its race-specific spectrum. This will not only build a better understanding of the genetic basis of apple scab resistance and the gene-for-gene relationships between the pathogen and the host, but it will enable the development of molecular markers for breeding new ‘sprayfree’ cultivars with durable scab resistance.

Mots clés : apple, disease, scab, resistance, candidate resistance gene, cloning, genetics, bioinformatics, plant transformation, agrobacterium transient gene expression

Participants :
- Fondazione Edmund Mach (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 238354.2 €
- Crown Research Institutes (Nouvelle-Zélande) — Partner, organization partner, Recherche, subvention : 0.0 €
Projet MIMetiCO (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Approximately 250 million people worldwide are visually impaired, and this has great economic and social impact. One of the pathologies of vision loss is keratoconus, in which the mechanical balance of the cornea depending on intraocular pressure and internal stresses in corneal tissue becomes imbalanced, which can result in a corneal protrusion. Corneal crosslinking (CXL) is a clinical treatment that increases the overall mechanical stiffness of the cornea by inducing chemical bounding between collagen molecules. CXL is the present of halting corneal ectasias, and the future of noninvasive refractive surgery. However, its micro/nano-mechanisms are not completely understood. Moreover, CXL is usually applied uniformly in corneal treatments, which can result in over-stiffening and unexpected postsurgical outcomes. Ophthalmology can benefit from in silico modeling to plan and improve such interventions. However, current computational models are mainly macroscopic and cannot simulate complex phenomena involved in CXL. Multiscale computational models could improve clinical strategies by including information at different scales. MIMetiCO’s goal is to combine experiments and modelling at different scales to provide a multiscale characterization of corneal biomechanics before and after CXL. This characterization will rely on both ground-breaking and well-established technologies that include confocal microscopy, biochemical assessment, and mechanical inflation tests to determine morphological (orientation and density of fibrils), biochemical (amount of intermolecular crosslinks), and mechanical features of the cornea. MIMetiCO will use this information to calibrate the first in silico model of the cornea using a multiscale structural approach to build a virtual framework to simulate potential CXL treatments. MIMetiCO is the next step in ophthalmology, which has the potential to bring into being a new generation of clinical assessment.

Mots clés : cornea, crosslinking, biomechanics, virtual simulation framework, multiscale experiments  confocal microscopy, mechanics and biochemical assessment, multiscale in silico modelling

Participants :
- University of Bern (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175419.6 €
Projet GENESIS (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Approximately 90% of the world's power is generated by fossil fuel combustion engines. These typically operate at 25-40% efficiency, such that globally ~15 TW is wasted as heat. Thermoelectric (TE) generators, which convert heat flow into useful electrical power, can potentially convert part of the waste heat to electricity and provide economic savings and environmental sustainability. TE modules can also be used as self-powered sensors in mobile applications, wearable electronics, etc. especially when connection to mains is limited, which makes them ideal for the ‘Internet of Things’ concept as well. One of the main challenges of the TE research area and industry is the identification and design of optimal materials out of the myriad possibilities of alloys and new generation material combinations. The GENESIS project addresses this challenge through advanced theory and simulations by constructing a well-validated, open-access generic computational machinery that can be used to simulate the thermoelectric (TE) properties of arbitrary targeted materials by using as input their electronic and phononic bandstructures. This will support the TE community in forecasting whether a particular material can be really suitable, as well as by providing better understanding of measurements, enabling time and cost reductions, which will accelerate the experimental efforts. Such a timely needed computational machinery is currently missing. Thus, the projects bridges the current gap between theory and experiment in the design of TE materials, and will allow the Experienced Researcher to establish himself as a computational materials scientist specialized in electro-thermal transport.

Mots clés : thermoelectric materials, charge and thermal transport, materials by design

Participants :
- University of Warwick (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet SAFE-Aqua (Horizon 2020, appel à projets 2016)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : CLOSED

Aquaculture is an important food source for the world’s growing population. The increasing demand and productivity of aquaculture leads to global trade in breeding stock, genetic material and aquaculture products for human consumption, but also exacerbates the globalization of pathogens.SAFE-Aqua, an international inter- and multidisciplinary consortium, aims to provide scientific solutions to solve disease-related issues in aquaculture using shrimp as a model through research and innovation staff exchange and sharing of knowledge and ideas from research to market. SAFE-Aqua will explore the benefits of developed feed additives on keeping a healthy gut microbial balance, enhancing immune-capacity, and maintaining nutritional integrity of shrimp as a product. To assess these beneficial effects, SAFE-Aqua will synergize the cutting-edge technology platforms, multidisciplinary and complementary expertise, as well as infrastructure from networks of the partnership among the leading research institutes in France, UK and Thailand and a synthetic biology company in Spain. The outcomes of SAFE-Aqua will undoubtedly help improve competitiveness of EU aquaculture industry whose growth has been relatively constant since year 2000 compared to aquaculture production worldwide. Moreover, we strongly believe that SAFE-Aqua will promote international and inter-sector collaboration through research and innovation staff exchanges and sharing of knowledge and ideas from research to market. The use of cutting-edge innovative technologies will allow to researchers to develop new skill sets helping them to develop their carreers in the best way. In addition administrative staff implicated in the project management will also greatly benefit from the knowledge exchange and build further collaborations.

Mots clés : aquaculture, shrimp, gut microbiota, prebiotics, probiotics, genome sequencing, metabolomics, interactomics, innate immunity

Participants :
- Bacmine sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 22500.0 €
- National Science and Technology Development Agency (Thaïlande) — Partner, organization partner, Recherche, subvention : 0.0 €
- Institut Pasteur (France) — Coordinator, beneficiary, Recherche, subvention : 396000.0 €
- Swansea University (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 252000.0 €
- Wageningen University & Research (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 229500.0 €
Projet WrightBros neXt (Horizon Europe, appel à projets 2023)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : SIGNED

The interdisciplinary WrightBros neXt project is designed as an extension, both in terms of the scope and the Consortium composition, of the “collaborative factory of the flight simulators branch of RISE” which was funded under H2020 programme and successfully completed as a WrightBroS project. Based on its results, the new concept of research on projectors-free flight simulators is proposed as an answer to challenges which occur when novel eXtended Reality (XR) technologies are applied to professional training of pilots. The goal of the new project is to: - develop innovative, projectors-free, flight simulators by using various XR technologies, and - compare the influence on human perception of various XR technologies used in these projectors-free flight simulators vs. classical setup with projector-generated scenery. The wide range of visualization setups developed in a collaboration between the Coordinator: Silesian University of Technology (SUT), Poland, flight simulators manufacturer: Virtual Reality Media (VRM), Slovakia, and software developer: LG Nexera (NXR), Austria, will be then tested by pilots during experimental sessions in Virtual Flight Laboratory at SUT. In such sessions the pilots will wear mobile EEG device capturing data about the influence of a given display system used in the flight simulator on a cognitive load and other brain activities. The assessment of the cognitive load, as a measure of the mental effort required to complete a task, will be made by SUT scientists in an interdisciplinary collaboration with the researchers from Psychology Department of University of Zadar (UOZ), Croatia. The EEG signals will be also analyzed by secondees from Dnipro University of Technology (DUT), Ukraine, hosted by SUT specialists experienced in signal processing and machine learning. The results will be used to predict real-time performance, fatigue, and stress levels of pilots testing particular XR visualization system used in the flight simulator.

Mots clés : flight simulators, human machine interaction, machine learning, scene recognition and understanding

Participants :
- LG (South Korea) (Autriche) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 18400.0 €
- Dnipro University of Technology (Ukraine) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 211600.0 €
- Virtual reality media as (Slovaquie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 18400.0 €
- École polytechnique de Silésie (Pologne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 966000.0 €
- Université de Zadar (Croatie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 156400.0 €
Projet IPOSEE (Horizon Europe, appel à projets 2021)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : SIGNED

Wireless networks have become indispensable to citizens, enterprises and vertical industries, e.g., transport (including autonomous vehicles and drones), logistics, utilities and manufacturing, because wireless connectivity is essential to the digital transformation of industrial and business processes and customer experiences. As a result, wireless networks are facing increasingly diverse service requirements, which indicate that existing reactive network management will be insufficient, while intelligent and proactive control of service-centric networks becomes essential. Future intelligent wireless networks rely on several multidisciplinary breakthroughs: (i) Artificial Intelligence (AI) algorithms that can accurately predict spatial-temporal patterns of service demand and thereby drive proactive optimisation of wireless networks, (ii) reconfigurable radio access networks (RAN) and wireless environments, and (iii) automated wireless service provisioning with reduced cost, improved performance and greater reliability. Current research to automate the optimisation of service-centric wireless networks using data-driven AI is facing many open challenges that need to be urgently addressed. In this project, we will take advantage of growing data availability and advanced data science technologies, as well as AI algorithms and techniques to deliver the above identified multidisciplinary breakthroughs, thereby enabling reliable automated wireless service provisioning.

Mots clés : service centric, wireless traffic forecasting, spatial temporal pattern, data analytics, uncertainty quantification, radio access network, intelligent reflecting surface, built environment, o ran ric

Participants :
- Chongqing University of Posts and Telecommunications (Chine) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université d'Uppsala (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 101200.0 €
- WINGS ICT Solutions (Greece) (Grèce) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 220800.0 €
- Mid Sweden University (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 50600.0 €
- Université de Sheffield (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Ranplan wireless network design ltd (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet NewFunFiCO (Horizon Europe, appel à projets 2021)
Action : Staff Exchanges
Panel : Physics
Statut du projet : SIGNED

The celebrated detection of gravitational waves (GWs), the first observation of horizon scale structure of a black hole (BH) together with the developments in the field of numerical relativity, are allowing access to extreme (strong and dynamical) gravity configurations, both observationally and theoretically, making our time a golden epoch for studying extreme gravitational systems.  In parallel, families of exotic but theoretically sound models of BHs and horizonless compact objects in the presence of new fundamental fields, or alternative theories of gravity have been constructed, to a large extent numerically. These can be submitted to computational experiments, to test their dynamics, and compared against observations, to address the issue of degeneracy in the theoretical interpretations of strong gravity data or even detect putative better fits to the data. At the meeting point between these two developments lies the promise of new fundamental physics, a deeper understanding of BHs and neutron stars, unveling the nature of dark matter and dark energy. Delivering on this promise requires a synergetic endeavour that must bring together different groups and competences. This project creates a multi-connected team with different and complementary scientific expertises - on BHs, neutron stars and exotic compact objects -, their phenomenology - GWs, lensing and astrophysical environments - and the techniques necessary to extract the latter from the former for comparison with observations, including constructing and evolving solutions of non-standard compact objects with numerical methods, building GW libraries, lensing images and performing data/Bayesian analysis and parameter estimation. The team includes members of the LIGO-Virgo-Kagra and Event Horizon Telescope collaborations, providing a direct connection to observations, and will explore deep learning frameworks to face the key challanges of model classification and data augmentation.

Mots clés : black holes, gravitational waves, numerical solutions, numerical relativity, deep learning

Participants :
- Université chinoise de Hong Kong (Chine) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Johann Wolfgang Goethe de Francfort-sur-le-Main (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 92000.0 €
- Université nationale autonome du Mexique (Mexique) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Valence (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 92000.0 €
- Université fédérale du Pará (Brésil) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université d'Aveiro (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 92000.0 €
Projet E-FORESTER (Horizon Europe, appel à projets 2023)
Action : Staff Exchanges
Panel : Environment and Geosciences
Statut du projet : SIGNED

The need to protect forests and cultural resources and preserve biodiversity are among the basic challenges of mankind. A step towards the effective implementation of these tasks is conducting the periodic, systematic inventory of naturThe need to protect forests and cultural resources and preserve biodiversity are among the basic challenges of mankind. A step towards the effective implementation of these tasks is conducting the periodic, systematic inventory of natural resources and their constant monitoring. Such activities require modern tools to assist in protecting the most valuable natural resources, including forests. In terms of monitoring and inventory of forests, there is planned an autonomous device, capable of navigating in a diverse environment and recording a wide variety of data. The main aim of E-FORESTER (Effective FOrest Research Electronic System Terrain Exploration Rover) project is to create and integrate, through staff exchange, an international team capable of responding to the challenges posed by the European Green Deal in the field of forestry. Such a large-scale project requires the selection and cooperation of an interdisciplinary team, which will include foresters, fauna and flora specialists, archaeologists, as well as engineers and machine learning analysts. The result of their work should be a rover with research tools, capable of operating continuously, regardless of terrain diversity and weather conditions, providing data and cartographic materials constituting documentation presenting the diversity of the forest environment. By detailed documenting plant and animal species, and through appropriate algorithms, also natural habitats, the project should also meet the challenges posed by of the European Union's tasks, which is the Natura 2000 network. Identification of archaeological relics through non-invasive methods will fulfil Valetta Convention (1992) recommendations and open a new area for archaeological/historical investigations.

Mots clés : automatic data collecting, automatic cropmarks identification, close range photogrammetry, laser scanning and remote sensing, topoclimatology, microclimatology, autonomous vehicles oriented

Participants :
- Université des sciences de la vie de Poznań (Pologne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 179400.0 €
- Université Adam-Mickiewicz de Poznań (Pologne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 340400.0 €
- Cyprus space exploration organisation (cseo) (Chypre) — Partner, beneficiary, Recherche, subvention : 105800.0 €
- Space systems solutions (s3)ltd (Chypre) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 561200.0 €
- S2g technologies s.r.l. (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 151800.0 €
- Université de Padoue (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 174800.0 €
Projet ARTVOC (Horizon Europe, appel à projets 2022)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

Volatolomics has emerged as a new frontier in deciphering unreached matters related with health conditions. Volatolomics research is based on the study of the volatile compounds emitted by biological samples. It was demonstrated that the volatiles emitted though breath, skin, feces, urine or cells can provide useful information for the diagnosis of an important number of diseases, such as cancer, diabetes, or even neurodegenerative disorders. We have very recently demonstrated that the embryos do also emit volatiles during their development, while genetical disorders alter the pattern of the released volatiles. In the present project, we aim at assessing volatolomic techniques for the non-invasive assessment of embryos quality in order to select the most viable ones for transfer. The ultimate goal of this project is to achieve higher success rates in the in vitro fertilisation.

Mots clés : volatile organic compounds gas chromatography mass spectrometry gc ms electronic nose embryo selection in vitro fertilisation

Participants :
- Cooperative University of Colombia (Colombie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Rovira i Virgili (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 326600.0 €
- Mgm star construct srl (Roumanie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 257600.0 €
- University of Pamplona (Colombie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Universiti Malaysia Sarawak (Malaisie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Caldas (Colombie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Estonian University of Life Sciences (Estonie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 552000.0 €
- Competence Centre on Health Technologies (Estonia) (Estonie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 358800.0 €