Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet TIKKS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Cardiovascular diseases, cancer, and sepsis are the leading causes of death worldwide. In all of them, a strong involvement of the endogenous kallikrein-kinin system (KKS) is postulated. However, the KKS is only rudimentarily understood, which is also reflected by the large proportion of developed drugs showing insufficient efficacy. The KKS is a 2-arm cascade that is present in both the blood as well as the tissue and its actions are mediated by the so-called kinins. Comprehensive insight into the cascade is greatly hindered by the lack of appropriate bioanalytical techniques. While the fellow has recently developed an innovative mass spectrometric method for the plasma KKS and applied in clinical studies, the tissue KKS has not yet been investigated, although the physiological action is likely exerted only in tissue. The advances in mass spectrometric imaging are currently used for metabolomics or mapping of biomolecules in tissue, but appear to be highly promising also for targeted kinin detection in the tissue KKS. The fellow with his key expertise in targeted mass spectrometric kinin quantification will use different mass spectrometric imaging techniques (DESI, MALDI, MasSpec Pen) to evaluate the tissue KKS. Hence, the TIKKS project is to first time study the presence, distribution, metabolism and overall profile of kinins in different (diseased) tissues by mass spectrometric imaging. For this purpose, various malignant tissues are examined as a main objective and subsequently extended to cardiovascular diseases and angioedema. This innovative approach will allow the fellow to uniquely investigate physiology and pathophysiology across both arms of the KKS (tissue & plasma) and therefore strengthen him on his path to his own professorship. The combined power of the innovative imaging approach and the already established mass spectrometric platform for plasma KKS will critically accelerate the discovery of promising drug targets for non-communicable diseases.

Mots clés : kallikrein kinin system, bradykinin, mass spectrometry

Participants :
- Baylor College of Medicine (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Heinrich Heine de Düsseldorf (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 265647.84 €
Projet EmbRace (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Muslims are the focus of political anxieties in Europe and the US. Over the last decade, numerous studies have documented the racialization of Muslims, and the impact of those discourses on those identified as such. Yet the embodied and sensorial dimension of the racialization of Muslims remains largely under-theorized. EmbRace posits that to better understand, and by extension tackle, the effects of (racial) discrimination in everyday life, we need not only to attend to statistics of reported racism or narrated accounts of racism, but also to the sensorial and bodily experience of it. This project takes recreational running as a fruitful angle to consider the embodiment of race. The leisurely activity of running enables an investigation of the effects of racialization on the relation to one’s own body, environment, and to other people. The research design utilizes a multimodal ethnographic approach. To reveal the embodiment of social hierarchies in social interactions among Muslim recreational athletes, this project has two main objectives: 1) Conceptualize how dispositions of non-belonging shape outdoor activities such as running and vice versa, by analysing movement and narratives of movement (conceptual/empirical goal) and 2) To examine and theorize the processes through which the multisensory dimensions of racialization become embodied (theoretical goal). By proposing a knowledge transfer between the researcher, Leiden University (The Netherlands) and University of California, Berkeley (USA), this project aims to contribute to the theorization of embodied senses of non-belonging.

Mots clés : racialization, embodiment, sport

Participants :
- Université de Leyde (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 199014.24 €
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet ATLANTIS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

ATLANTIS tackles the multifaceted challenges facing academia today by focusing on alternatives articulated within or at the boundaries of higher education. These challenges are not only practical, but also deeply theoretical and engage fundamental epistemological and ontological discussions about the intertwinedness of science and society, and the knowledge this relation generates. Using Francis Bacon’s New Atlantis (1626) as a reference point, this project’s ambition is to co-create different narratives, infrastructures and frameworks that amend the consequences of the technocratic imaginaries of knowledge and progress crystallised in this story. Following the lead of researchers that have taken people’s hopes and visions as objects of analysis and entry points into broader societal concerns, ATLANTIS aims to: 1) develop a nuanced account of the diverse challenges facing academia and better understand emergent or successful responses and transformation; and 2) co-create possible and utopian academic worlds that open new horizons for meaningful discussions and paradigm-shifting actions that account for its current weaknesses and blind spots, particularly when it comes to gender and multispecies entanglements. ATLANTIS is anchored in anthropology and science and technology studies (STS) and focuses on three distinct but interconnected lines of inquiry about academia and its future at the present (neoliberal) moment. ATLANTIS takes a forward-looking approach that is historically and ethnographically grounded, while engaging innovative co-creation and future-oriented techniques articulated at the intersection of anthropology, innovation, and design. ATLANTIS is hosted at the Norwegian University of Science and Technology (NTNU) and includes a secondment at the University of California, Los Angeles (UCLA). It is co-supervised by Vivian Anette Lagesen, Knut H. Sørensen, and Sharon Traweek.

Mots clés : anthropology, neoliberalism, academia universities epistemic living spaces, futures, hope, gender, multispecies entanglements, new atlantis

Participants :
- Université norvégienne de sciences et de technologie (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 226751.04 €
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet VertiSeed SelECT (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Global crop yield losses caused by fungal pathogens are estimated to range from 10% to 20%, amounting to $100-$200 billion per annum. The widespread use of fungicides has a significant negative impact on the environment, and the growing resistance to fungicides is further exacerbating the problem. Adopting sustainable agricultural practices is crucial for effectively combating fungal pathogens while also remaining environmentally friendly. Natural microbiome-based anti-fungal approaches are both more sustainable and less subject to development of fungal resistance. As an MSCA PostDoc Fellow, Dr. Aqueel will investigate the Brassica microbiome in Dr. Devlin’s lab at Royal Holloway University of London. The microbiomes of susceptible and resistant cultivars have different microbial communities and metabolic pathways, reflecting disease resistance mechanisms. Through disease incidence assays we will isolate Plant Growth Promoting Bacteria (PGPB) responsible for the disease suppressing capabilities combating fungal pathogens like Alternaria and Fusarium. As the main outcome of our research, we present a novel strategy for application of these PGPB SynComs via vertical transmission as endophytes, developing stable bio-primed seeds. The researcher will also receive training under a 6-month non-academic placement at Tozer Seeds Ltd where extensive field trials will test the efficacy of these bio-primed seeds in the field as well as their stability and seed storage stability. Dr. Aqueel has an outstanding research track record, publishing in well-reputed international journals, presenting internationally and developing long-term collaborations. Dr Devlin has extensive experience in the field of plant-microbiome interaction as well as in mentoring early career professionals. In addition to developing ground-breaking innovation, the experience gained by the researcher at RHUL and Tozer Seeds Ltd. will greatly benefit her in her future career in industry and academia.

Mots clés : plant microbiome, sustainable agriculture, disease suppression, vertical transmission, alternaria, fusarium

Participants :
- Royal Holloway (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 325434.9 €
- Tozer seeds limited (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet SBI-Cardio (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The 3D, time-resolved blood flow measurement technique known as 4D Flow Magnetic Resonance Imaging (MRI) is highly valuable for research and can play a crucial role in cardiovascular disease (CVD) diagnosis and treatment planning. However, it is limited by the fundamental trade-off between resolution, image quality, and scan time since current 4D Flow MRI methods use compressed sensing or spatiotemporal acceleration to achieve only a spatial resolution of 1-3mm and temporal resolution of 25-100ms in a scan time of ~10 minutes. To overcome this challenge, simulation-based imaging (SBI) may provide a method to augment 4D flow MRI data by fitting computational fluid dynamics (CFD) simulation to low-resolution and noisy 4D Flow MRI data. The primary objective of SBI is to generate a high-resolution velocity field by optimizing the simulation to closely match the available data. This approach overcomes the aforementioned limitations of 4D Flow MRI, which often suffers from inherent errors in resolution and scan time, leading to both quantitative and qualitative discrepancies. By utilizing SBI, a more precise and comprehensive visualization of blood flow can be achieved. Therefore, the ultimate goal of this project is to develop a novel SBI method for MRI that will be used to address a wide range of cardiovascular (CVDs) such as heart attacks, strokes, and congenital heart defects; providing high-quality images of structure and function with ultra-high resolution and fast scan time. The long-term impact of the proposed SBI framework is expected to revolutionize clinical diagnosis and surgical decision-making leading to more effective treatments and improved outcomes for CVD patients.

Mots clés : simulation based imaging 4d flow mri blood flow computational fluid dynamics high resolution imaging cardiovascular disease diagnosis wall shear stress

Participants :
- Université de Lund (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut de technologie de Chypre (Chypre) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 164328.0 €
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet NexGenRE (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

As outlined in the European Strategy for Particle Physics, the field is entering a pivotal era with major initiatives such as the completion of the LHC, the proposal for a "Higgs factory," and the development of next-generation hadron collider. This project responds to these advancements by focusing on the design and development of state-of-the-art readout electronics, specifically innovative Analog-to-Digital Converters (ADCs). These ADCs are critical for enhancing data acquisition systems in high-energy physics (HEP) experiments, impacting the precision and reliability of experimental data. By tackling the challenges of achieving high resolution, speed, compactness, and low power consumption, this project aims to advance detector technology and support the exploration of fundamental physics. Additionally, the proposed advancements will have broad applicability in nuclear physics, medical imaging, and other fields that utilize advanced particle detection technologies.

Mots clés : detector readout, readout electronics

Participants :
- Université rhénane Frédéric-Guillaume de Bonn (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 101062.56 €
Projet SEAMS (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The SEAMS project aims to investigate the wrapping weaves of votive animal mummies, a religious phenomenon which was widely spread throughout Egypt between the Third Intermediate Period and the Roman Period (1069 BCE-380 CE ca.). SEAMS is set to fill the gap in current knowledge on the contextual data of votive animal mummies and shed light on their manufacture through an innovative multidisciplinary and interdisciplinary methodology that integrates traditional research approaches with new technologies. This study has never been undertaken before since Egyptologists have long paid relatively little attention to these artefacts. The project will contribute to the advancement of this field by reconstructing the original integrity of the wrapping patterns of specimens held in international museums through photogrammetry, MSI techniques, and virtual restoration. The multi-scalar and cross analysis of the restored 3D replicas and their related data allows the recurring patterns to be identified and grouped into typologies. The stylistic assessment of recurring wrapping weaves combined with further information from archives, fieldwork, and CT-scans enables their occurrence within a specific period and/or site to be recorded and any potential meanings unravelled. Textile and experimental archaeology protocols are set to provide an understanding of how the bandages were held in tension, what the interweaving stages were, and which tools were used. Furthermore, a comprehensive account of the quality and quantity of the resources, technologies and efforts employed permits an evaluation of the economic weight of the wrapping procedures. The research outcomes are to be widely shared through open science practices, outreach activities, a free and open access visual repository, and a temporary exhibition on votive animal mummies that will contribute towards generating knowledge about these long-neglected artefacts.

Mots clés : animal mummies, wrapping weaves, craft, religious beliefs, digital humanities, experimental archaeology

Participants :
- Université de Copenhague (Danemark) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Lund (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Fondazione museo delle antichita egizie di torino (Italie) — Coordinator, beneficiary, Autres, subvention : 265099.2 €
- Conseil national de la recherche (Italie) — Partner, associated partner, Recherche, subvention : 0.0 €
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet IMPACT4Mech (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

This project will develop innovative control strategies for the mechatronic technologies of the next decade, bolstering the design of sustainable industrial, energy, and transportation systems. Motivated by the vast development gap between several emerging technologies, such as smart materials and additively manufactured systems, and the algorithms for their safe and high-performance operation, we aim to design control techniques to handle unconventional dynamics with impacts, discrete events, and hysteresis phenomena, including large disturbances and modeling uncertainties. Specifically, we propose to embrace the formalism of hybrid dynamical systems to achieve a quantum leap of internal model and adaptive control, leading to an impact for next-generation mechatronics. This aim represents an ideal evolution for the activities of the candidate fellow, Dr. Alessandro Bosso, in a perspective of knowledge consolidation and career development in the academic world. To this end, under the supervision of Prof. Andrea Tilli and the co-supervision of Prof. Lorenzo Marconi at the University of Bologna, the project foresees an intense training and research program, where the fellow will be mentored by leading experts in hybrid and mechatronic systems. During the outgoing phase, Dr. Bosso will be hosted for 16 months at the CCDC of UC Santa Barbara, a world-leading center in control research and related multi- disciplinary topics that formed many successful scientists in the field. There, the fellow will be supervised by Prof. Andrew R. Teel, a prominent researcher among the founders of hybrid systems theory. Then, a secondment period of 8 months is planned at the laboratories LAAS and LAPLACE of the CNRS in Toulouse, France, where Prof. Luca Zaccarian will guide the fellow in theoretical and applied research. Finally, the return phase will be dedicated to developing breakthrough laboratory prototypes and disseminating the results to the scientific and industrial communities.

Mots clés : hybrid dynamical systems adaptive control internal model control mechatronics

Participants :
- Centre national de la recherche scientifique (France) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Bologne (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 265099.2 €
- University of California System (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet PL-LiDAR (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Presently, EU citizens who live in urban areas (approx. 70% of the EU population) are exposed to airborne pollutants at levels that are damaging to health. To tackle this, the EU Commission has set an ambitious goal to transform 100 European cities into climate- neutral and smart cities by 2030, with the rest to follow by 2050. LiDAR (light detection and ranging) systems have the potential to be used in heavily urbanized areas to monitor traffic congestion and provide measurements of atmospheric contaminants. Nevertheless, current LiDAR systems suffer from poor free-space-to-fiber collection due to the use of single-mode fibers and lack the necessary collection efficiency, working range, and performance to be deployed at large scales in the smart and neutral city network. Here, we propose the development of novel photonic lantern-based LiDAR systems for CO2 and atmospheric mapping. Photonic lanterns are novel optical fiber devices that efficiently couple a multimode beam to single-mode fibers to take advantage of the performance of single-mode components. Using photonic lanterns, we can significantly increase the collection efficiency of the LiDAR system (at least 19x) and ease the complexity and size of the collection telescope. This can result in the development of portable high-performance LiDAR systems that can be used in heavily urbanized cities to generate high-resolution 3D maps of CO2 emissions and correlate them with traffic congestion. The proposed research will have significant ramifications on the life quality of millions of people while becoming a crucial pillar in the successful deployment of future climate-neutral and smart cities.


Participants :
- Raymetrics anonymi etairia anaptyksis systimaton ipsilis technologias (Grèce) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Institut de technologie de Chypre (Chypre) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 190219.44 €
- University of Central Florida (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet HYDROCOUPLE (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

HYDROCOUPLE proposes to develop (1) a new coupled finite element (FE) method for environmental flows, (2) goal-oriented adaptive mesh refinement strategies, and (3) to apply the new techniques to physical watersheds for verification of its capabilities as well as to demonstrate these. The project is a collaboration between three researchers, the applicant Eirik Valseth (currently at The University of Texas at Austin), Prof. Kent-Andre Mardal (The University of Oslo) and Prof. Ethan Kubatko (The Ohio State University). Many current approximation techniques for multiphysics phenomena, where two or more models (partial differential equations) govern the physics, focuses on the approximation of these as separate phenomena and prescribe appropriate interface conditions to exchange information between the models. Recent attention has been given to monolithically coupled methods (Kuchta et al. 2021), where all models are approximated simultaneously thanks to careful algorithm design and numerical analysis. HYDROCOUPLE will extend the theory of these monolithic coupling schemes to environmental flow problems and develop a FE framework for their corresponding numerical approximation. This developed framework can subsequently be applied in flood prediction and hydropower production planning as the models in environmental flows govern both overland and riverine flows which are critical in both applications. HYDROCOUPLE will also develop mesh-adaptive refinement techniques based on goal-oriented error estimation to ensure the high fidelity of its numerical approximations. Finally, the proposed framework will be verified against available data for existing watersheds to demonstrate its efficiency and accuracy to end users in industry and government. Working in the Section of Mechanics at the Department of Mathematics with a world renowned scientist will provide a perfect setting to integrate my knowledge and start my research career in Europe.

Mots clés : finite element methods, hydraulic flows, multiphysics, flood prediction, hydropower production prediction, 

Participants :
- Université d'Oslo (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 226751.04 €
- Université d'État de l'Ohio (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €