Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet TheoFem (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

The overarching objective of this project is to demonstrate European Catholic lay women's vital contributions as international agents, thinkers and theologians avant-la-lettre, from the end of World War II up to the celebration of the Second Vatican Council (1945-1962). While several studies have dealt with lay (and religious) women during and after the Council, their pioneer role as intellectuals and international experts in the pre-conciliar years has significantly received less attention. The history of this period has mostly been written in strikingly national, secular and rather masculine terms. A crucial aspect of the period was the Church’s attempt to expand the ranks of lay International Catholic Organisations (ICOs). As a result of their engagement in shaping pastoral strategies, international policies and agenda setting, lay women in positions of leadership became experts, they travelled extensively, and gradually adopted ‘female’ forms of agency as a route into male-dominated arenas (theology, international relations and action) By paying particular attention to the entangled history of Belgium and Spain (both understood in their relationship to the wider Spanish and French speaking Catholic worlds), by adopting an interdisciplinary approach (political and social sciences, visual and intellectual cultures, theology, anthropology) and a gender perspective, the project will 1) systematically recover and establish a ‘genealogy’ of lay women's intellectual agency; 2) map and conceptualise their collective action and transnational networks; 3) illustrate the strategies used to consolidate communities of secular and religious knowledge (including alternative forms of governability); 4) visualise their legacies. In this manner the project aims to contribute to reconfigure public perceptions about women in positions of leadership, and to the promotion of gender equality and more reflective European societies.

Mots clés : women and gender studies, transnational networks, religious history, international catholic organisations, humanitarianism

Participants :
- Fondazione per le scienze religiose giovanni xxiii (Italie) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université d'Anvers (Belgique) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191760.0 €
Projet PENTEX (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

A common practice throughout much of the history of Christianity, the expulsion of demonic entities, also known as exorcism, continues to occur on a regular basis in the capital cities of Europe. These religious rituals are customary in Pentecostalism, a form of Protestantism that grew exponentially in the last century, especially in Lain America and Africa. However, although most of the studies about Pentecostalism in the Global South observe the importance of exorcisms, the literature about this religious movement's diaspora to Europe focuses more on the integration of participants in a migratory context, which leaves a gap in the analysis of these researches. Thus, PENTEX aims to analyse Pentecostal exorcisms in two Pentecostal churches (one from Latin America and one from Africa) in London, United Kingdom, by acknowledging these rituals' creative (in which outside practices are re-signified) and integrative (in which they control and regulated the participants' practices and social roles) features. Furthermore, PENTEX aims to observe the conviviality of Pentecostals with other social groups in London and the role and adaptation of exorcisms in these interactions. PENTEX will also analyse cases of violence in the city that resemble Pentecostal exorcisms, by observing if the churches' spiritual warfare against evil and demonisation may materialize into violence, and how the participants, NGOs that promote human rights, and policymakers understand these cases.

Mots clés : exorcisms pentecostalism migration

Participants :
- Université d'Utrecht (Pays-Bas) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175920.0 €
Projet brainTEaser (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

The human brain is the largest and most complex of all primates possessing unique cognitive functions but also suffering from neurological disorders. However, little is known about primate brain development and the modifications enabling brain enlargement as primate tissues are not available at early developmental time points. Only few changes occurred in protein-coding genes; thus, significant differences must be present in gene regulatory processes. It is essential to analyse primate models to identify and understand molecular features unique to the human brain. Transposable elements (TEs) are mobile pieces of DNA comprising 50% of primate genomes. They can contribute to genome evolution as they carry regulatory sequences and have been found to serve for example, as enhancers and alternative promoters. Moreover, TEs are insertional mutagens leading to genetic disease. They are silenced by repressive marks including DNA methylation. Interestingly, methylation can sometimes spread and impact adjacent regions making TEs noteworthy candidates for methylome evolution. Due to their challenging analysis and lack of primate material, the role of TEs in primate brain development and human brain evolution has not been investigated thoroughly. Here, I propose that human-specific TE insertions have the capacity to act as repressors and silence genes in brain development. Exploiting human and non-human primate cerebral organoids as a model for brain development, and Oxford Nanopore Technologies long-read DNA sequencing to detect DNA methylation, I will analyse locus-specific TE methylation spread to nearby genes. Using differential expression analysis and CRISPR-Cas9 genome editing, I will assess the effect of putative repressor TEs on gene expression revealing if the repression of specific loci contributed to human brain enlargement and gain of cognitive functions.

Mots clés : transposable element, te, retrotransposon, dna methylation, epigenetics, nanopore sequencing, oxford nanopore technologies, cerebral organoids, neuronal differentiation, crispr cas9

Participants :
- Université de Lund (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 210187.68 €
Projet PRESSMAG (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The pressure attracts noticeable attention in the field of condensed matter physics because it can modify magnetic and electronic properties of the compounds. The external pressure can induce both structural and magnetic phase transitions giving experimental access to novel magnetic phenomena. This makes pressure a promising tool to customize the magnetic properties of solid-state compounds both at the base and finite temperatures. However, no comprehensive study has been done so far on the investigation of the pressure effects on overall magnetic properties such as Hamiltonian, magnetic structure, and critical behavior of a model magnetic system. I address these issues in the PRESSMAG project which explores “the pressure effects on magnetic properties of an ideal quasi-2D planar antiferromagnet BaNi2V2O8 at the base and finite temperatures”. First, I will solve the magnetic structure and Hamiltonian of BaNi2V2O8 under applied pressures and then will study the critical behavior of BaNi2V2O8 under applied pressures using both neutron and x-ray scattering techniques. In particular, the PRESSMAG project will study for the first time the pressure effects on the Berezinskii-Kosterlitz-Thousless phenomena, whose signatures were recently discovered in BaNi2V2O8. Finally, the small-angle-neutron-scattering technique will be used to image the Berezinskii-Kosterlitz-Thousless vortices in vacuum and under applied pressure.

Mots clés : honeycomb antiferromagnets, berezinskii kosterlitz thousless transition, long range magnetic order, correlation length, critical exponent

Participants :
- Université de Lund (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 222727.68 €
Projet INFORM (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Lightweight structures are becoming increasingly essential to meet global emission regulations. Fiber-reinforced composites (FRPs) constitute a highly profitable and fast-growing market for the EU. Their high stiffness and strength and design flexibility enable designing lightweight structures with a low carbon footprint. In contrast, two main drawbacks hinder their industrial exploitation: poor delamination resistance and limited design space due to the lack of robust design tools and the limited capability of past production technologies. Fiber hybridization (i.e., combining two or more fiber types) increases their design space and can improve their toughness. Thus, fiber-hybrid FRPs are rapidly gaining market share in structural applications. Unfortunately, delamination modeling is challenging because several damage mechanisms occur simultaneously and interact at multiple physical length-scales. This fellowship will tackle these issues by developing novel fiber-hybrid (INFORM) FRPs by combining carbon and glass fibers to minimize delaminations, thus addressing current industrial needs for damage tolerance, weight savings, and sustainability. A multi-scale analytical and numerical approach will be developed to understand and analyze INFORM FRPs with unique performances. The optimal INFORM structures will be manufactured, tested, and analyzed through detailed damage analyses to build a fine-tuned design tool. This design tool will be translated into industry-friendly packages for direct exploitation. Automated manufacturing technologies (e.g., 3D printing) will also be used to tailor INFORM designs locally. Thus, macro-components will be created with locally improved delamination resistance without a weight increase. The fellowship will take place at KUL. The training plan, research work, and dissemination activities will serve as ideal preparation for the ER to lead a research group in or out of academia in the future.

Mots clés : carbon fiber composites, interlaminar fracture, solid mechanics, finite element modeling, damage tolerance

Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175920.0 €
Projet MagMD (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Water scarcity and pollution are key global threats, and to generate water from seawater or brackish water and the effective reuse of industrial wastewater are essential to achieve the sustainable development goals and carbon neutrality. Membrane distillation (MD) is inherently a problem-solver for high salinity seawater and wastewater, and is recognized as an effective strategy for zero liquid discharge (ZLD). However, membrane fouling and wetting are two key issues, which impede its industrial application. MagMD is an application-oriented project, intending to introduce the “magnetic magic” into hydrophobic membrane with a “material- mechanism- application” route, targeting at the commercial application of MD. Three magneto-responsive membranes (magMEMs) will be prepared by incorporating Fe3O4, in order to explore the effects of surface & bulk nano-heating, nano-mixing, and hydrophilic modification on MD. Then, the molecular fouling mechanisms will be demonstrated by combining membrane autopsy, extended-Derjaguin-Landau-Verwey-Overbeek theory (XDLVO), and density functional theory (DFT). The wetting mechanism and the effect of surface & bulk nano-heating on wetting mitigation will also be revealed by water evaporation rate test and long-term MD process. The magMEMs are used for RO concentrate treatment, by applying an alternating magnetic field (AMF) for real-time fouling and wetting mitigation. The long-term performance and the membrane fouling distribution and mechanism will be studied to evaluate the potential of industrial applications. MagMD will uncover the “magic” of magnetism and advance the membrane fouling & wetting mitigation theories and methods. The results will pave a new way for smart gating membrane, and offer a new solution for fouling and wetting control in MD. It will contribute to both state-of-the-art theoretical advancements and practical implementations of MD, bring significant environmental, economic, and social benefits.

Mots clés : magnetic responsive membrane membrane distillation smart gating membrane membrane fouling membrane wetting xdlvo density functional theory desalination industrial wastewater treatment

Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191760.0 €
Projet EMOTE (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

Depression and psychosis in adolescents and emerging adults have a significant economic, health, and social burden on an international scale. Targeting transdiagnostic factors that are common across disorders, and doing so early before symptoms develop or worsen, is critical to maximise impact and get more bang for buck. Anhedonia, the pervasive inability to anticipate and experience pleasure or interest, is a transdiagnostic feature of depression and psychosis. Anhedonia has received comparatively little research attention compared to other symptoms, meaning that it is not well understood or addressed in therapy. The current research will use existing high-quality datasets in an ambitious exploration of the emotional processes related to anhedonia in depression and psychosis, with a focus on adolescents and emerging adults. It will extend prior research by using advanced real-time methodologies that provide a fine-grained and temporal understanding of emotional experiences in anhedonia in daily life. This approach will dramatically advance the field by aiding the future development of transdiagnostic techniques targeting anhedonia that are more effective than those currently available. The workplan also outlines training and career development activities that focus on experience sampling methodology, complex multilevel and time series data analysis, open science, and building transferable professional skills to lead an independent and productive lab. These skills will underpin the fellow’s ability to establish a profile as an up-and-coming researcher with a competitive edge for funding and employment. The research fellow and supervisor are the ideal team to conduct this work. The fellow’s strong background in research on youth depression and digital programs delivered at scale complements the methodological expertise of the supervisor, who is an expert in psychosis and real-time data collection methods in real-world contexts.

Mots clés : psychiatric disorders

Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191760.0 €
Projet SCHELLEC (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The contemporary environmental crisis has triggered a revival of discussions on the concept of nature. Among scientists, philosophers, policy makers and citizens questions regarding environmental practices and the overall state of nature have become a matter of central concern. But what exactly is nature beyond the specific phenomena studied by specialized natural sciences, such as physics, chemistry or biology? Is there something else beyond these particular phenomena? What is the relationship between these phenomena and humanity? Do humans have a special status in relation to nature? On my account, these questions are at the core of the philosophy of nature that Schelling developed at the turn of the 19th century in response to the increasing instrumentalization of nature. More precisely, I take Schelling’s philosophy of nature to address versions of these same questions, especially as regards (a) the unity of nature beyond the phenomena studied by emerging scientific disciplines such as chemistry and biology, and (b) the status of humanity in relation to this unity. The overall aim of the project is to bring out the contemporary relevance of Schelling’s philosophy of nature by investigating it as an attempt to address these challenges. Counteracting mystical readings of Schelling’s project, I will argue (1) that he is concerned with the elaboration of a unified account of the phenomena studied in the natural sciences; (2) that his theory of self-organization aims to provide such an account; (3) that he conceives of the distinction between humans and non-human forms of nature as a distinction of degree; and (4) that this conception of nature as the manifestation of different degrees of self-organization is relevant to contemporary debates in that it forges a middle path between anthropocentric and non-anthropocentric approaches to nature.

Mots clés : schelling, philosophy of nature, history of science, self organization, environmental ethics

Participants :
- Université de Cambridge (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 190242.0 €
Projet HoLi (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

My research project will investigate the effects of certain forms of interpreting and experiencing Islam on the production of moral subjects and the shaping of individual trajectories and social practices, by focusing on women participaMy research project will investigate how Muslim spaces are created in diasporic Muslim contexts from an anthropological perspective. It will analyse the role that religious practices and discourses play in home-making processes and in the production of different levels of belonging among religiously committed Muslim women. Through the analysis of the complex ways in which the shaping of an ideal Muslim self intermingles with actualizations of home outside homeland, I will untangle the mechanisms through which space is made home in diverse diasporic contexts and further anthropological understandings of how religiously framed practices can shape subjects capable of living throughout the globalized world. I will, particularly, consider the ways in which women negotiate and respond to moral constraints in the different arenas that constitute their everyday practices, both inside and outside their community, and how and to which extent those moral constraints affect their individual autonomy. In order to do that, I will conduct ethnographic fieldwork through participant observation with women members of the Gülen Movement in Belgium, whose participants are Turkish followers of the charismatic religious leader Fethullah Gülen. The proposed project builds upon, expands and further develops my doctoral research on the construction of moral subjects among women of the Gülen Movement in Brazil, which demonstrates that the performance of Islamic practices as they are understood by Gülen’s followers, produces a conditioned agency among women. The research project will broaden my ethnographic universe and allow me to take a comparative approach to better understand the Gülen Movement as a whole and the specificities to its localized communities.

Mots clés : g len movement turkish islam ritual practices subjectivity muslim women muslim diaspora

Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191760.0 €
Projet HDACbyCRYOEM (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Histone deacetylase (HDAC) complexes are the main transcriptional repression machineries in eukaryotes. Disruption of their functions can lead to various diseases such as cancers, inflammatory diseases, and neurological disorders. HDAC complexes are composed of multiple subunits that assemble around HDAC enzymes, which have been the most exploited targets for developing small molecule therapeutics. To expand the diversity of targets and inhibitors available to study HDAC complex biology and fight HDAC-related diseases, the applicant developed phenotypic screens focused on the Sin3 HDAC complex in human and yeast during his PhD training. He also used proteomics approaches to study the global cellular effects of new compounds and predict their targets. However, the absence of high-resolution 3D structures for the Sin3 HDAC complex has hampered the precise understanding and validation of how drugs bind to specific subunits and perturb the overall architecture of the complex to reprogram its biological functions.  Here, we are combining the expertise of the applicant in HDAC complex biology and druggability, to that of his host laboratory in cryo-electron microscopy (cryo-EM) to solve the 3D structures of the human and yeast Sin3 HDAC complex at near atomic resolution. This complex is highly conserved between species and is formed by a dozen proteins, making it an ideal candidate for single-particle cryo-EM. The applicant has already acquired promising preliminary data, including partial purifications of both human and yeast Sin3 HDAC complexes. The pioneer structures that will emerge from this work will have a high impact in the fields of transcriptomics and epigenetics since they will improve our understanding of HDAC complex arrangements, while helping validating long-standing hypotheses on transcriptional repression mechanisms. The proposed 3D models will also serve as starting points for further systematic structure-based design of new HDAC complex inhibitors.


Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191760.0 €