Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet ReMIND (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

ReMIND focuses on the potentials for ‘mind museums’(former asylums turned into museums)to provoke emotional responses in visitors and foster critical reflection on the histories and contemporary problems of dealing with mental illness (MI) in society.Its objective is to fill some relevant scientific gaps on the subject, as well as to conjoin complimentary disciplinary approaches from museum and exhibition design and museum studies and develop new research competence for me as fellow and for the host institution in the field of visitor studies. ReMIND explores the MI heritage landscape through asylums built in Europe from the mid-19th cent until the 60s’ deinstitutionalisation process in the psychiatric care system.Today, most of these buildings still stand where they were, often completely or partially abandoned, left to decay, and contributing to urban decline.ReMIND will survey the European landscape of MI heritage considering phenomena such as abandonment and reuse of historic asylums for cultural purposes.However, alongside this general desk-based overview, its main aim is to analyse former asylums that have been restored and reused as museums, specifically involving 2 indepth interdisciplinary pilot case studies.Nowadays we don’t have a sense of potentials for the responsible adaptive re-use of asylums and they are in danger.Likewise, once converted into museums, their role in effecting attitudinal change in visitors that may help to dismantle stigma and promote awareness toward MI has not been properly investigated.ReMIND addresses these gaps. To do so my study will integrate various disciplinary approaches to rethink adaptive reuse interventions and contemporary heritage conservation and valorisation practices.I will work at the intersection of different research fields, moving from Italy to UK at New Castle University to learn, deploy and contribute in implementing theories and methodologies related to heritage studies, visitor studies, and display analysis.

Mots clés : adaptive reuse, architecture, critical heritage studies, museum studies, difficult heritage, neglected heritage, exhibition desing, built environment

Participants :
- Newcastle University (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 224933.76 €
Projet VSDN (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Recent advances in mobile devices and video streaming services have motivated large-scale media consumption both in fixed and mobile environments. In this context, the main objective of network operators and service providers is to improve the Quality of Experience (QoE) of the end-users by providing high quality services and mechanisms for seamless adaptation to the specific network conditions of each user. However, the initial design of the Internet as a best-effort network makes it inappropriate for high-volume and bandwidth-intensive applications, like video streaming, and the centralised architectures employed by the network operators lead to long, non-optimal communication paths between clients and servers, waste of network resources and increased delays. The improvement of the QoE of multimedia communication services require novel network architectures and cross-layer adaptation mechanisms. Specifically, at the network layer, Software Defined Networking (SDN) enables the virtualisation of the network functions so that the network operators implement their own rules and policies in software and deploy them in an abstracted and virtualised network infrastructure. At the application layer, the Dynamic Adaptive Streaming over HTTP (DASH) approach enables the seamless adaptation of the video client to the specific network conditions of each user. The understanding of how the network parameters affect the human perception is a key factor in optimizing the functions in the end-to-end delivery chain. The V-SDN project aims at developing a QoE-driven media delivery platform based on network virtualisation functionalities, which takes into account the service utility functions, network topology, link capacities and the specific QoE requirements of each application. The developed QoE-driven media delivery platform will be implemented and demonstrated with an innovative media delivery system employing a novel DASH client, a further key development of the project.

Mots clés : video streaming, quality of experience, software defined networking

Participants :
- Athens University of Economics and Business (Grèce) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 152653.2 €
Projet DNPMAT (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Recent innovations in dynamic nuclear polarization (DNP) have transformed the sensitivity of solid-state nuclear magnetic resonance (NMR), resulting in a reduction in experiment time of up to 100,000-fold. This means that previously unobtainable structural details can be quickly obtained by NMR, even for dilute species, such as binding sites in catalysts or functionalizing molecules at surfaces. The objectives of the action are the improved sample preparation protocols, new experimental approaches and proof of principle studies necessary to make DNP-enhanced solid-state NMR the method of choice for the molecular-level characterization of the surfaces of materials. These objectives will be achieved by knowledge exchange between Dr S. Chaudhari, an experienced researcher with a background in developing DNP, and researchers at the University of Nottingham involved in solid-state NMR studies of materials and catalysts. The action is designed to train Dr Chaudhari though high-quality research into applications of DNP-enhanced solid-state NMR to four technologically useful materials: mesocellular silica foams, alumina catalyst supports, surface-coated hydroxyapatite nanoparticles and model catalytic converters. The training will take place at the state-of-the-art UK Facility for DNP-enhanced solid-state NMR operational at the University of Nottingham since November 2015. The Facility’s instrumentation is unique in the UK and is available to external users from both industry and academia, resulting in a vibrant research environment and a ready-made network of collaborators for Dr Chaudhari. In addition, a secondment at a leading sustainable technology company (Johnson Matthey) will ensure that industrial and commercial aspects are fully integrated into the action. The training will transform Dr Chaudhari into a creative and independent scientist working at the frontiers of DNP-enhanced NMR by providing him with the necessary research knowledge and transferable skills.

Mots clés : solid state nuclear magnetic resonance, dynamic nuclear polarization

Participants :
- University of Nottingham (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet SAPTiMeC (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Recently, researchers in the field of bottom-up synthetic biology have developed different models of non-living cell-like entities, termed protocells. Protocells are designed to mimic basic aspects of living cells and have potential applications in various emerging technologies. Prototissues comprise networks of protocell consortia that communicate and display synergistic functions. Though the current designs contribute much to the development of bottom-up synthetic biology, they lack robustness and the complexity required to perform higher-order functions. The aim of this proposal is to advance the prototissue design to create prototissues capable of higher-order functions (i.e. photo-mechano-chemical transduction). The prototissues will be created by stratifying and patterning populations of specialised protocells. As a result, the prototissue will be able to self-regulate the amount of luminous energy received from the environment by opening and closing cyclically. This movement enables the prototissue to tune its endogenous photocatalytic reactivity, producing waves of an output chemical signal. The expertise of the applicant in photochemistry, materials and nanomaterials chemistry will be applied to the emerging field of prototissue engineering, area in which the hosting supervisor is an emerging leader. The approach will be focussed on the generation of macroscopic free-standing prototissue sheets with complex architectures. This process will be used to create phototropic prototissues upon exploiting photoresponsive hydrogels encapsulated in their building blocks. The resulting phototropic prototissues will be modified in order to contain building blocks with photocatalytic synthetic proto-organelles. Collectively, the outcome of this proposal will: kickstart a new area of bottom-up synthetic biology; provide a new approach to the construction of out-of-equilibrium systems; and deliver new materials with applications in tissue engineering and soft robotics.

Mots clés : out of equilibrium, self regulating, photoactuators, soft robotics

Participants :
- University of Bristol (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 26616.72 €
- University of Trieste (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 150039.12 €
Projet LoStPReCon (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Recently, the re-assessment of the collapse of the Koror-Babeldaob Bridge (in 1996), a pre-stressed bridge built by the cantilever method, concluded that this was due to excessive deflections that appeared and grew non-linearly some years after construction. Interestingly, similar trends were found for a group of 56 similar bridge spans, raising the question whether such concerns could influence the maintenance and service life of a high number of pre-stressed bridges in Europe and beyond. Although individual material and structural factors have been researched, this problem can only be solved by integrating physical and probabilistic models and benefiting from the increasing use of monitoring data. This proposal aims to: 1.Review existing models for shrinkage and creep at specimen level, 2.Establish robust hybrid FE models for medium/long-term predictions, 3.Develop a novel monitoring approach based on Digital Image Correlation (DIC), 4.Formulate a time-dependent reliability assessment framework, addressing creep and shrinkage uncertainties, 5.Produce representative performance-time profiles for pre-stressed bridges based on the proposed framework and models. The above will be demonstrated via a case study – the Lezíria Bridge – possessing a unique combination of factors: (i) available monitoring data, (ii) pre-existing analysis models and (iii) an intimate knowledge by Dr. Helder Sousa, the researcher, of its construction and behaviour. The findings will be directly relevant to the growing number of bridges with this problem, enhancing the European knowledge and competitiveness in the global infrastructure market. For this, an interdisciplinary research and training programme has been set out, building on the researcher’s strong track record, expanding/honing his knowledge/skills, so that he can reach the forefront of highly qualified professionals able to solve problems in a creative/integrative manner, contributing to European expertise and wealth creation.

Mots clés : pre stressed concrete bridges, structural reliability, fe modeling, shrinkage, creep, infrastructure asset management

Participants :
- University of Surrey (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet TLRstorm (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Recognition of nucleic acids enables detection of diverse pathogens by a limited number of innate immune receptors, but also exposes the host to potential autoimmunity. At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA or DNA, respectively, and contribute to the pathology of autoimmune diseases. Despite the structural and functional similarities between these two receptors, they can have opposing effects in autoimmune diseases such as systemic lupus erythematosus. My previous studies have identified a potential explanation for this enigma, whereby TLR7 and TLR9 experience a surprising degree of differential regulation, both at the level of receptor trafficking as well as receptor activation in the endosome. Although my work provides a major conceptual advance for explaining the distinct behavior of these two receptors in disease, we still poorly understand how the regulation of nucleic acid-sensing TLRs and its various interactions and pathways are embedded into the cellular architecture. Their cellular location is not trivial: knowing where in the cell these critical interactions take place and how they are coordinated in time is of utmost importance to fully understand how TLRs are regulated to avoid self-recognition. In this project, I aim to investigate these fundamental aspects of TLR biology using state-of-the art superresolution microscopy. I will use sub-diffraction imaging techniques including stochastic optical reconstruction microscopy (STORM) and Airyscanning technology to 1) define the precise subcellular localization of nucleic acid-sensing TLRs, 2) identify and characterize their endosomal signaling compartments, and 3) investigate TLR signaling dynamics under normal and autoimmune-prone conditions. This work will provide a conceptual framework for understanding how TLR signaling is controlled in space and time and define the molecular principles that maintain self-tolerance to nucleic acids.

Mots clés : superresolution microscopy, single molecule, toll like receptors, endosomes, myd88, crispr, cas9

Participants :
- Freie Universität Berlin (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 162806.4 €
Projet REGDAM (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Regulatory T cells (TREG) are critical players in the control of innate and adaptive immune responses while impacting as well on the functional output of parenchyma tissues. This later effect is exerted by tissue-resident TREG, via an ill-defined mechanism that modulates tissue damage control, that is, a protective response of parenchyma tissues that limits cellular dysfunction and/or damage imposed by inflammation and immunity. The central hypothesis to be tested under this proposal is that tissue-resident TREG modulate tissue damage control via a number of adaptive responses to cellular stress, which preserve the functional outputs of parenchyma tissues. Failure of tissue-resident TREG to modulate adaptive responses to oxidative and hypoxic stress should exacerbate the deleterious effects imposed by these forms of stress on parenchyma cells and as such promote the pathogenesis of immune mediated inflammatory diseases. Under this Marie-Curie fellowship we will address mechanistically how TREG receive signals from tissues exposed to oxidative and hypoxic stress and migrate to those tissues to modulate oxidative and hypoxic stress responses as to dampen tissue damage.

Mots clés : treg, disease tolerance, foxp3, stress and damage response

Participants :
- Calouste Gulbenkian Foundation (Portugal) — Coordinator, beneficiary, Recherche, subvention : 148635.6 €
Projet GREEN-FRC (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Reinforced doncrete urban infrastructure poses significant, insufficiently addressed, environmental challenges due to impacts from cement, natural aggregate and steel reinforcement production. This proposal focuses on integrating fibre reinforced concrete (FRC) with “green” concretes produced with waste and recycled materials. The large scatter of current FRC characterisation tests leads to conservative structural design and the incomplete understanding of waste and recycled materials’ effects on “green” concrete properties leads to quality control challenges. As a result, existing standards and design codes are not comprehensive and the market uptake of these concretes is low. This action proposes a synergy of FRC and “green” concretes to achieve fully sustainable urban infrastructure. The action will develop and optimise structural-grade “green” FRC (G-FRC) with different recycled and waste materials for maximising sustainability; develop novel G-FRC characterisation tests with reduced result scatter; formulate performance-based indicators for recycled and waste materials used in G-FRC to facilitate quality control; and develop design guidelines for G-FRC structures with full-scale structural test verification and in-situ application, within 24 months of project duration. The expertise of the experienced researcher (ER), Dr. Nikola Tošić, and the supervisor, Dr. Alberto de la Fuente Antequera, are fully complementary and will enable them to develop novel research techniques through a two-way knowledge transfer and comprehensive training activities for the ER. The project will engage Smart Engineering Ltd for industrial application of project results. Comprehensive dissemination and communication measures focusing on different target audiences are formulated. A carefully thought through and detailed work plan, resource use, and contingency measures for risk mitigation have been developed to ensure a smooth and timely project implementation with maximised impact.

Mots clés : concrete, concrete structures, structural design, reliability, urban infrastructure, recycling, waste, fibre reinforced concrete, optimisation, multi criteria decision making

Participants :
- Universitat Politècnica de Catalunya (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 160932.48 €
Projet ReS4ToM (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Remote sensing of the troposphere with Global Navigation Satellite Systems (GNSS) provides observations of spatial and temporal resolution higher than any other technique and operates under all weather conditions. The main product of GNSS meteorology, the zenith troposphere delay (ZTD), can be assimilated into numerical weather prediction (NWP) models in order to improve forecasting. The troposphere is also a major error source in GNSS positioning and a limiting factor for Interferometric Synthetic Aperture Radar (InSAR) observations. Both techniques are commonly used for hazard warning systems, which raise the demand for reliable real-time (RT) ZTD models. Accuracy and timely provision of ZTD estimates is limited by the quality and latency of satellite orbit and clock products. In 2013, the International GNSS Service started to provide RT products for GNSS, thus opening new possibilities for GNSS meteorology. Preliminary results revealed absolute accuracies of RT ZTDs of less than 30 mm, which is better than any other existing ZTD model available in RT. In order to further improve the quality of RT GNSS ZTD models we will make use of emerging GNSS, modify functional and stochastic models for data processing and provide sophisticated RT products i.e. troposphere gradients and slant delays. We will apply novel approaches in order to improve GNSS monitoring and correct InSAR observations, with the goal to better support RT earthquake and landslide warning systems. The aim of this project is to develop a high-quality RT GNSS model of the troposphere on two scales: dense regional (Germany, Poland) and sparse continental (Europe). The host at the University of Stuttgart, has vast experience in the development of next-generation positioning, navigation and timing solutions, and can provide the crucial infrastructure for this project. Secondments at the German Meteorological Service and the Federal Agency for Cartography and Geodesy will provide additional trainings.

Mots clés : gnss meteorology, real time, remote sensing, troposphere, zenith troposphere delay, numerical, weather prediction

Participants :
- University of Stuttgart (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 174806.4 €
Projet FUTBOL (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Remote thermal sensing and imaging is currently one of the most prominent technological fields. Its market value is expected to grow beyond $10 billion/year by 2020. The simplicity and low price of uncooled radiation heat sensors, bolometers, have made them subjected for extensive research. The route for improved performance is enhanced absorption of thermal radiation, improved thermal isolation, reduced thermal mass, increased sensitivity of thermal transduction and reduced noise. Atomically thin crystalline materials, 2D materials, are an attractive alternative to traditional bolometer materials. Their extreme aspect ratio allows for excellent thermal isolation, low thermal mass, and electrostatically tunable electrical and optical properties allows for temperature sensing and strong light-matter interaction. FUTBOL aims to take the advantage of 2D materials, as new bolometer material, to create a novel sensor with unseen resolution and bandwidth. A strip of 2D material is suspended to thermally isolate it from its surroundings and form a Fabry-Pérot cavity. Thermal radiation is partly absorbed and partly transmitted into the cavity where it resonates. As the 2D material is not a perfect mirror it will eventually absorb a large fraction of the radiation. The conductivity of the 2D material is electrostatically tuned, using the gate voltage, to maximize absorption. It is utilized that an ultrathin metallic layer reaches 100% absorption when its resistance equals the product of the layer thickness times the vacuum impedance. Absorption of radiation leads to heating of the thermally self-sensing 2D material which is transduced either via changes in its electrical resistance or mechanical resonance frequency. Advantages of the bolometer design are minimal thermal mass, excellent thermal isolation, short time constant and the ability to electrostatically tune the absorption of radiation, combined leading to unseen resolution and bandwidth.

Mots clés : bolometer, nems, 2d materials, mos2, nanoscale

Participants :
- Board of the Swiss Federal Institutes of Technology (Suisse) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 187419.6 €
Projet MFP (Horizon 2020, appel à projets 2020)
Action : MSCA other
Statut du projet : CLOSED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.

Mots clés : social care, care services, care providers

Participants :
- Rovira i Virgili University (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 30000.0 €