Projet PRISAR2 (Horizon 2020, appel à projets 2019)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

From 2016 -2019, the “first” PRISAR consortium implemented the first Dutch RISE project of H2020 to investigate the use of imaging technologies and hybrid fluorescence/radionuclide probes for the surgical intervention of cancer. This PRISAR project provided a career-enabling human resource plethora of inter-disciplinary and inter-sectoral secondments, which resulted in the development, of not only a hybrid probe for image-guided surgery, but also a variety of tools and instruments. We now propose a new project, PRISAR2, to implement the next logical phase of this work, which is to clinically translate new and innovative monitoring technologies from industry. This will provide better patient selection and increase the surveillance window to allow for better treatment options over time and avoid surgery. This will involve developing new ‘watch and wait’ strategies to study the behaviour of the cancer so that any risks can be minimized. This would lead to a better clinical outcome and quality of life (QOL) for the patient and maximize the benefits of an active monitoring policy for both the patient and the healthcare system. When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Here, however, we aim to (a) develop new monitoring technologies from industry so that the surveillance window can be increased to allow for better treatment options over time and to avoid surgery, (b) develop new ‘watch and wait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to a better clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this new concept as standard of care and to maximise the benefits of an active monitoring policy.

Mots clés : tool development, physical sciences, rectal cancer, active monitoring, surveillance, imaging, watchandwait, diagnostics

Participants :
- Associazione hand in hand (Italie) — Partner, beneficiary, Autres, subvention : 69000.0 €
- University of Naples Federico II (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 110400.0 €
- Tecobiosciences gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 110400.0 €
- Université de Strasbourg (France) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 55200.0 €
- Seranovo bv (Pays-Bas) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 55200.0 €
- Chipdx ivs (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 165600.0 €
- Associazione tourism (Italie) — Partner, beneficiary, Autres, subvention : 124200.0 €
- Università di Camerino (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 110400.0 €
- Des solutio - solucoes e consultoria cientifica lda (Portugal) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 82800.0 €
- Heinrich Heine University Düsseldorf (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 165600.0 €
- Surgimab sas (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 55200.0 €
- Erasmus MC (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 55200.0 €
- Fujifilm sonosite bv (Pays-Bas) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 55200.0 €
- University of Sheffield (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 55200.0 €
- Datar cancer genetics (europe) gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 101200.0 €
- Progredum gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 92000.0 €
- Leiden University Medical Center (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 110400.0 €
- Percuros (Netherlands) (Pays-Bas) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 331200.0 €
- University of Liverpool (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 27600.0 €
- Hammersmith Medicines Research (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 27600.0 €
- Nemi territorio e turismo (Italie) — Partner, beneficiary, Autres, subvention : 55200.0 €
- Universitätsmedizin Göttingen (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 138000.0 €
- Technical University of Zvolen (Slovaquie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 165600.0 €
- University of Edinburgh (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 55200.0 €
- Corner House (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 110400.0 €