Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet Syn4WCO2-Cem (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Portland cement (PC) production is responsible for 7% of global CO2 emissions, and construction and demolition waste represent the largest waste stream in the EU, accounting for over one-third of all waste. These factors pose significant threats to sustainable development. To address these challenges, the Syn4WCO2-Cem project aims to align with the European Green Deal by promoting a circular economy within the construction sector. The primary objective of the project is to treat recycled concrete powder (RCP) by capturing CO2 from cement plant flue gases and to develop low-carbon cement composites using carbonated RCP (CRCP). One of the main challenges of low-carbon cement is its slow hydration kinetics within the first three days, which impedes the development of early strength. Currently, the particle dissolution rates in PC-CRCP blends and their C-S-H gel shell feature are not well understood. Gaining insight into the interactions between these parameters and strength-enhancing admixtures is crucial for accelerating the hydration process in a more mechanistic and scientifically grounded manner, rather than relying on the current trial-and-error approaches. The project seeks to address this critical knowledge gap by training fellow at the host institution (UMA) and utilizing advanced X-ray tools, including laboratory and synchrotron-based in situ X-ray imaging and diffraction, to visualize the hydration process of this low-carbon cement family. This comprehensive approach will help clarify the underlying mechanisms of the slow hydration process and develop effective strategies to accelerate it. The interdisciplinary innovation in this project will ensure that this low-carbon cement can achieve a 60% reduction in CO2 emissions compared to traditional PC-based binder while maintaining competitive performances. The project offers a unique opportunity for fellow to gain a competitive edge in the emerging field of “sustainable and green building materials”.

Mots clés : portland cement hydration recycled concrete carbonation synchrotron 4d x ray imaging microct

Participants :
- Université de Malaga (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 194074.56 €
Projet NUVAPY-BLUE (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Nutricosmeceutical develops products to improve health through the use of bioactive compounds (BACs). Algae are organisms that have a wide variety of BACs, high productivity and can be produced without irrigation or arable land. Following EU Green Deal and Blue Economy, the proposal aims to increase the macroalgae Porphyra/Pyropia productivity in consortium with fish, to produce high value BACs naturally and make nutricosmeceutical more attractive to the market. To reach this objective, the project will focus in: Porphyra production on a large scale using integrated multitrophic aquaculture with fishpond effluents from Chelon labrosus for alga growing, optimizing natural production of BACs; extract and purify BACs through biorefinery strategy; perform BACs encapsulation and test their sun protection, stability, toxicity, bioavailability; and develop topical and oral sunscreens. Researches shows some abiotic factors for BACs development and production in Porphyra, however there is a lack of studies that correlate various abiotic factors along with fish culture for a circular economy and better algae development. The project will produce biofertilizers and biostimulants from residual algal biomass, after extractions, which has not yet been optimized. Natural sunscreens are still scarce on the market, due to the lack of standards in extracts with stability for use in products and low BACs availability. The project’s interdisciplinarity is strong involving aquaculture, biochemistry, biotechnology and nutricosmeceutical. This 24-month long proposal includes both the transfer of knowledge to the host institution and the researcher’s training in new techniques. Furthermore, this project will place the researcher and the host institution in a leading role on natural production of Porphyra and BACs with emphasis in nutricosmetical industry. It will make the researcher more employable and competitive in applying for future roles, continuing in academic and/or industrial area

Mots clés : bioactive compounds, algae, nutraceutics, sunscreens, integrated multitrophic aquaculture

Participants :
- Université de Malaga (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet SENTINEL (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Hazardous weather events affecting populated coastal are among the most devastating natural disasters in terms of mortality and economical losses due to their low predictability. Currently, the generation of useful predictions, reliable and anticipated of hazardous weather events affecting populated coastal regions remains an ambitious challenge for the scientific community. Deficiencies in the accurate prediction of such events are tightly related with the initial value problem, which states that better the state of the atmosphere is estimated, the more accurate the forecasts. This problem is addressed by using advanced Data Assimilation (DA) techniques, which play an important role in current numerical weather prediction and is currently at the forefront of atmospheric and oceanic sciences research. However, although using the most current sophisticated DA algorithms, the estimation of the atmosphere is not accurate enough to improve the predictability of hazardous weather events, mainly because their linear and Gaussian underlying assumptions. The main aim of the present project is to go beyond the state of the art in DA by developing and implementing a novel and advanced DA technique that takes nonlinearities and non-Gaussianities into account, enabling us to to improve high-impact weather forecasts. The new DA will be tested in real cases in combination with a high-resolution atmospheric model to improve the predictability of several poorly forecasted Mediterranean Hurricanes. This novel technique will significantly improve global, regional, and climate forecasts. The applicant’s strong mathematical and theoretical skills in DA together with his broad experience running numerical weather models using HPC facilities will facilitate the achievement of the key goals of this proposal. This project will also expand the applicant’s experience, research competencies and professional networks, enhancing the development of his career as an independent researcher.

Mots clés : data assimilation, ensemble kalman filter, non gaussian, nonlinear processes, numerical weather forecasts, mediterranean hurricanes

Participants :
- Université des îles Baléares (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 165312.96 €
Projet CoralMath (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Coral reefs are one of the most biologically diverse ecosystems on Earth, but their regression has largely increased in the last decades due to local human pressures and global warming. This project aims to use numerical models and simulations to expand our understanding of coral reefs' dynamics and improve marine conservation strategies. I will follow an interdisciplinary approach, using complex systems and non-linear physics techniques combined with ecological knowledge and field data of coral reef systems. My results will be the foundation to study a large variety of open questions in coral reef science using an innovative and ground-breaking point of view. In this project, I will focus on two applications of the models: i) the study of the underlying mechanisms causing the emergence of halo-like patterns around reef islands (grazing halos) and ii) the construction of a protocol to optimize and reduce costs in coral restoration programs. I expect my results to have a high impact on the scientific community and contribute to making better and more informed decisions about the sustainable management of coastal zones, in line with the new EU Biodiversity Strategy for 2030 - a comprehensive, ambitious, long-term plan for protecting nature and reversing the degradation of ecosystems aiming to put Europe's biodiversity on a path to recovery by 2030 with benefits for people, the climate and the planet.

Mots clés : non linear physics, self organization and emergent phenomena, marine ecology, coral reef ecosystems, marine restoration programs

Participants :
- Université d'Hawaï (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université des îles Baléares (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 216699.6 €
Projet CULTEMO (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

CULTEMO’s aim is to examine a set of implicit norms about human emotional life that took shape in the mid-twentieth century and which continue to dominate scientific frameworks and clinical practices to the detriment of patients and progress in the science of emotion. Since the 1970s, researchers and psychiatrists have used the concept of alexithymia to assert that individuals who lack words (lexis) to communicate emotions (thymos) have a potential risk factor for several affective disorders. But not all cultures and languages share the same understanding of human emotional life, or even have equivalent linguistic terms for emotions and feelings, leaving some patients vulnerable to mistreatment in encounters with the psychiatric system. By projecting its perspective as the universal, natural norm for all human beings, the alexithymia construct marginalizes and even pathologizes the diverse ways that individuals make sense of their bodily sentience and the world around them. With alexithymia as a lens, CULTEMO will apply recent evidence and methods from the affective sciences, cross-cultural psychology, social ontology, and the medical humanities to reveal the faulty assumptions of a view of emotions as natural and universal. CULTEMO’s working hypothesis is that an understanding of emotions as situated, relational, and historical can help clinicians practice epistemic humility in encounters with patients who do not operate with the same kinds of emotion scripts or norms as themselves, minorities especially. Building on these historical, philosophical, and scientific insights, CULTEMO will produce educational material for the general public and clinical practice.

Mots clés : philosophy of emotion, philosophy of psychology, history of psychiatry, social ontology, minorities

Participants :
- Université de Copenhague (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 355549.68 €
- Université Northeastern (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Sundhedsstyrelsen (Danemark) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
Projet REDAVIP (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Every individual carries at least a herpesvirus causing mild to serious diseases without definitive cure. Although in theory, herpesvirus genomes can be degraded by host DNA nucleases (DNASEs), the ER preliminary data has evidenced DNASE2B protein levels to decrease upon herpes simplex virus-1 (HSV-1) infection. In order to restore DNASEs anti-viral potential, REDAVIP aims to 1) uncover the susceptibility of DNASEs to HSV-1, 2) gain mechanistic insights of HSV-1 proteins and DNASEs interaction, and 3) screen drugs restoring host DNASEs so the vDNA can be cleared from the organism. To do so, REDAVIP will assess DNASEs’ endogenous levels upon infection by immunoblot and enrich them with immunoprecipitation to identify interacting viral protein(s) by mass spectrometry collaborating internationally. Afterwards, their minimal interacting surfaces will be determined and disrupted with in silico drug library screens collaborating internationally. Then, a tripartite fluorescence complementation assay will confirm the disruption of this pathogenic interaction in cellula. Candidate compounds restoring the DNASEs ability of degrading vDNA will be validated by plaque assays for IP protection, since they may represent a first step towards an overdue cure against herpesviral infections and life quality improvement, especially for an ageing population. Given the ambitious and novel objectives, the ER applies her multidisciplinary expertise to propose mitigation strategies that will ensure experimental feasibility and multiple outputs. This work will allow the ER to transfer her knowledge acquired through European laboratories to the acceptor institution, and progress from basic to translational research to learn and ensure a revenue of invested funds. The findings will be broadly disseminated to improve the ER soft skills. Uncovering how host DNASEs are impaired during herpesvirus infection using HSV-1 as a model is an asset to find novel antivirals against further viruses.

Mots clés : herpesvirus, dnases, proteomics, drug screens, fluorescence complementation

Participants :
- Université Miguel-Hernández (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet BonEggHens (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Skeletal disorders in laying hens are a major concern for the food industry. It is well recognized that bone demineralization in laying hens is coupled to the daily mobilization of Ca for egg formation but the relation between bone properties and eggshell quality is still unclear. A key point for understanding this coupled process is reveling the factors that influence bone dissolution since the unbalance between resorption and formation is what causes bone diseases such as osteoporosis and osteogenesis imperfecta. Notably, there is limited information on how the composition, structural organization and interaction between bone mineral phase and organic matrix in different bone types influence chicken bone dissolution and its mechanical properties. BonEggHens aims to perform a systematic study, from macro to nanoscopic scale, on a large array of bone and eggshell samples representative of the hen’s life cycle, to assess i) the effect of the mineral labile phase and the organic matrix on bone dissolution, ii) the relation between micro and nanoscopic characteristics of hen’s bones to bone quality parameters (e.g., bone density, mineral crystallinity) and iii) the correlation between bone structural and compositional changes and eggshell quality. The results of the proposed study will shed light on bone/eggshell (de)mineralization processes, which will help to find solutions for a more sustainable yet productive farming system for ovo-production. Moreover, the outcome of BonEggHens has potential implications for future biomineral investigation by cutting-edge microscopy tools and, most importantly, for the study of human bone diseases resembling those in chickens. Finally, the development of the proposal will be career-defining, contributing to the professional and personal growth of the experienced researcher and providing the necessary skills and competences to increase her competitiveness and attain a permanent position in the European scientific framework.

Mots clés : geochemistry, biominerals, dissolution, skeletal disorders, animal welfare, tem, micro raman, atom probe tomography, atr ftir

Participants :
- Université d'Oviedo (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- GFZ Helmholtz Centre for Geosciences (Allemagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Grenade (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet VisHeK (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Between the 10th and 12th centuries CE, the major players of the Mediterranean included the Republic of Venice, Norman Sicily, Fatimid Egypt, and North Africa, the Iberian Peninsula and Byzantium. Each of these centres was inhabited by a mixed population of Jews, Muslims, and Christians who maintained networks of trading partners, exchanging not only goods but also ideas, texts, and, as we will see, art. From the 12th century onward, Jewish scholars, mainly in Spain, Provence, and Italy, began translating scientific works from other languages; Hebrew became dominant as a scientific language. Jews were aware of the scientific developments and the translators gave different reasons justifying their motivations, such as the contempt displayed by foreign peoples for Jewish culture in general, or the conscious desire to embrace the knowledge and development of the surrounding culture in this field. While researchers have examined which and how scientific texts were translated from Latin and Arabic into Hebrew, they have paid little attention to whether and how Jews adopted the visual elements in these texts. Such visual components in Hebrew manuscripts of science and philosophy, mostly in the form of diagrams combining text and shape, stand at the heart of this project. Different diagrams that develop ideas in these fields will be analyzed for the first time, using methods from the disciplines of art history and history of science, with additional attention to manuscript studies and cultural history, emphasizing the interdisciplinary methods required in this field. Although the diagrams are found in Hebrew manuscripts, they are part of a wider context of Latin and Arabic manuscripts. The main aim of this integrative study of the transmission of text and image is to contribute to our understanding of the transfer and sharing of knowledge between different cultures.

Mots clés : jewish history, history of science, medieval manuscripts, illuminated manuscripts, jewish art history, hebrew manuscripts, jewish christian relations, interculturality, discourse, visual language

Participants :
- Université de Grenade (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet SENS_GRAV (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Although gravity sensation is not easy to sense, it is extrapolated by combining multisensory information. Due to this integrative nature of gravity perception, the knowledge regarding the molecular and neural basis of gravity sensing is highly reduced. The relevance of geotaxis behaviors in insect pest crop survival has been well documented. For instance, harvesting maize imposes a positive geotaxis behavior on the European corn borer (Ostrinia nubilalis), where diapause larvae and pupae are found close to the ground (contrary to what is observed in wild conditions). This adaptive behavior increases its survival and, indeed, its agricultural damage. In addition, larvae show a stereotype orientation when diapausing, suggesting that gravity vector plays a critical role in maggot spatial perception and physiology. In Drosophila, a well-studied insect genetic model, the maggot has a positive geotaxis at early stages, which changes to negative geotaxis at the wandering time (prepupariation period). However, magot gravity perception has never been confirmed or studied. Interestingly, wandering larvae exit the food source searching for an appropriate pupation site, displaying body position and orientation changes. Herein, I propose to take advantage of wandering orientation changes to set up a novel geotaxis behavioral assay and disclose gravity sensory modality in the maggot by i) screening for sensory organs involved in gravity sensing, ii) disclosing the neurocircuitry involved in puparium orientation behavior, and iii) studying the consequences of puparium orientation alteration on adult fitness. I expect this exploratory proposal to establish a solid basis for working further in the physiological impact of insect spatial orientation and the practical use of this knowledge on pest management.

Mots clés : gravity adaptation, drosophila melanogaster, insect crop pest, metamorphosis, ecdysis

Participants :
- Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (France) — Coordinator, beneficiary, Recherche, subvention : 195914.88 €
Projet M2IbAE (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Age estimation (AE) is an important topic that has witnessed an increased attention, given its role in various daily issues, from health assessment and social interaction to human identification. In turn, age-at-death estimation can contribute to the identification of a deceased by reducing the number of possible candidates while providing a further line of evidence to guide a possible identification. A related sensitive casuistry is the AE of unaccompanied minors, required in court so that migrants whose real age is unknown do not have their rights threatened. Other problems where legal age estimation could have an impact are child brides and prostitution. Last but not least, precise AE can contribute to solving disputes in competitive sports with strict age limits.  In practice, all the methods currently used for AE continue to be carried out manually, based on observations of macroscopic (visual observation) and morphometric (linear measurements) type.  The nature of all these problems fits perfectly within the scope of Artificial Intelligence (AI). The massive digitisation of skeletal remains would open the door to the application of AI, especially to models based on Deep Learning, that excel with complex data such as images and 3D models. The final goal and expected impact of M2IbAE is to allow practitioners to shift from current observational methods to automatic, objective and robust AE with unprecedented accuracy. Considering current limitations and challenges, together with the different forensic and societal needs and possibilities at a global scale, Panacea aim to achieve this goal by: (1) Developing the first set of age-at-death estimation methods from bone photographs together with a novel multifactorial and multimodal approach; (2) Developing a novel methodological approach to legal AE by exploiting synergies of different radiological images, x-ray and CT, of several anatomical regions, wrist, teeth, clavicle.

Mots clés : legal medicine, forensic anthropology, artificial intelligence, machine learning, biological profile, forensic radiology, medical engineering and technology

Participants :
- Panacea cooperative research s coop (Espagne) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 194074.56 €
- Université de Grenade (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €