Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet MarCyan (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

The curiosity and the interest of Humanity in space exploration lead to important discoveries on fundamental questions about our place in the Universe, and push forward the development of new technologies, new industries, and important international relationships. Mars is the nearest planet to Earth, has evidence of water, an element essential for life, and a geological history similar to Earth. These characteristics turn it a source of inspiration and a possible home for humans in the future. However, it is an inhospitable place and several solutions are being pursued in order to help terraform the planet. Atmospheric composition, cosmic radiation, temperature, and the lack of a protective magnetic field are just a few of the problems that Humankind needs to face prior to considering Mars colonization. However, there is a group of organisms that can be used to help solve some of the problems – Cyanobacteria. Why? Because they are simple oxygen producer organisms, with low nutritional requirements, and able to live in a wide range of extreme conditions and ecosystems. Moreover, cyanobacteria can also be used as food sources, to produce biofuels, in bioremediation, and as biofertilizers, for instance, and already proved to be good candidates for the task. MarCyan has the major goal of investigate the possible use of cyanobacteria to support Mars exploration. How? Using extremophile cyanobacteria, isolated from a Mars analog site (Rio Tinto, Spain), and submitted to Mars-like conditions in specialized Planetary Simulation Chambers. Moreover, MarCyan intends to go beyond the conventional knowledge and will use transcriptomic and metabolomic analysis to uncover the possible mechanisms that can help to explain the survival of these organisms to extreme conditions, opening the door to a more conscious choice of the best organisms to be used in Space exploration.

Mots clés : astrobiology mars cyanobacteria extremophile planetary simulation chambers

Participants :
- National Institute for Aerospace Technology (Espagne) — Coordinator, beneficiary, Recherche, subvention : 186331.16 €
Projet PROMINENCE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

The finite nature of fossil-fuel assets and the drive to dwindle the global carbon footprints are escalating research into alternative fuel and chemical production technologies. One of the most studied approaches is transforming CO2 into a value-added product, which in turn lessens its abundance in the atmosphere. Among all the existing CO2 reduction (CO2R) methods, the photoelectrochemical (PEC) is the most promising, as it uses abundant solar energy to convert CO2 into high-value chemicals, combining both the benefits of photocatalysis and electrocatalysis. Nevertheless, there are only a few reports on the PEC-CO2R by molecular catalyst (majorly using noble metals Ru and Re) to produce CO, a crucial primary building block for chemicals with high technological and economic feasibility. In this context, an electron-rich NHC-Mn(I)-carbonyl catalyst has been proposed for CO2R to produce CO with high selectivity at low overpotential and provide a potential platform to elucidate in-depth mechanistic studies, which are rare in this area. The sought mechanistic understanding can lead to the design of improved catalysts under optimal operating conditions. The project will be implemented by a multifaceted approach involving synthesis, characterisation, catalysis, and computations and further enriched by the immobilisation of the catalyst on the semiconducting metal oxide surface to produce a suitable photocathode for PEC reduction of CO2. We anticipate that this approach will deliver catalysts with a lower overpotential while maintaining the exceptional activity of the catalysts (TON, TOF, FE, QY). The earth-abundant Mn-catalyst anchored on a heterogeneous surface can be integrated into devices for artificial photosynthesis by combining it with a suitable photoanode. The project is also expected to lead to high-impact fundamental knowledge, and the results will be widely disseminated through publications in leading journals, symposia, conferences, and workshops.

Mots clés : photoelectrochemical, co2 reduction, nhc, manganese complex, surface immobilised

Participants :
- Institute of Chemical Research of Catalonia (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet FLUOR-DIOX (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Catalytic chain-walking reactions have recently emerged as a powerful tool for efficiently introducing functionalities at remote sp3 C–H sites within alkyl side chains. Nevertheless, substantial challenges remain when forging multiple C–C bonds while maintaining a predictable site-selectivity profile in chain-walking scenarios, particularly by controlling both regioselectivity and enantioselectivity. This project will explore the ability to introduce both fluorinated fragments and CO2 at an unsaturated hydrocarbon via dual photoredox/nickel catalysis with a predictable selectivity pattern. Such a transformation constitutes an unrecognized opportunity in chain-walking scenarios for introducing, at will, fluorinated fragments and carboxylic acid functions in a dual, yet modular, site-selective manner. Aimed at exploring the full potential of such an approach for accessing added-value fluoroalkyl carboxylic acids, a new class of C2-symmetric ligands will be rationally designed and developed. The impact that this technique might have in industrial endeavors will be assessed in collaboration with industrial partners of the host group by its application in late-stage modification of advanced intermediates, radiolabeling, and the synthesis of MRI probes.

Mots clés : nickel catalysis, chain walking, carbon dioxide fixation, difunctionalization, c h functionalization

Participants :
- Institute of Chemical Research of Catalonia (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet EUKPHYLEVOL (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Animals, plants, and fungi, which evolved multicellularity independently from their unicellular ancestors, represent only a small minority of the many branches on the eukaryotic tree of life, while the most of eukaryotic diversity is represented by microbial eukaryotes, or protists. Heterotrophic flagellates have been found in all major eukaryotic lineages and represent the most ancient and ancestral cellular organization. Heterotrophic flagellates often occupy early-branching or intermediate evolutionary positions within eukaryotes, thus comprehensive studies of novel lineages of heterotrophic flagellates not only fill the gaps in microbial diversity and phylogeny, but also help to understand the origin and evolution of major, well-known and diverse eukaryotic groups. Moreover, elements of the flagellar apparatus are homologous in all eukaryotes and are an excellent tool of comparative morphology to help interpret molecular phylogenetic data. The main goal of this project is to culture new and important protist lineages occupying key positions in the eukaryotic tree of life and to characterize their biology by linking sequence information to morphological, life history, and ecological traits. I propose two parallel Objectives on morphological and molecular characterization of previously unknown and understudied deeply branching lineages of eukaryotes, Collodictyonida and Rhizaria, that are both of critical importance in understanding eukaryotic evolution.

Mots clés : heterotrophic flagellates, protists, early eukaryotic evolution, molecular phylogeny, morphology, ultrastructure, light and electron microscopy

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 209914.56 €
Projet MDTF (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

MDFT focuses on the mixing and dispersion (M&D) of passive solutes in two-phase flow through heterogeneous porous media, which are key processes for the assessment of subsurface engineering applications such as underground hydrogen storage, geological carbon dioxide storage, enhanced oil recovery, groundwater and soil remediation. Despite their importance, M&D mechanisms in immiscible, miscible, and reactive two-phase systems are not well understood due to the complexity inherent to both flow and medium structure. M&D in single-phase flows is determined by medium heterogeneity that leads to the formation of lamellar structures (dispersion, stirring) of dissolved substances that homogenize through aggregation and coalescence (mixing). In two-phase flows, M&D is more complex because of stirring and dispersion actions induced by the two-phase interactions between fluid phases. Based on these fundamental principles we propose to develop a novel M&D theory for multiphase flow in immiscibe, miscible and reactive two-phase flow systems. To this end, MDFT will quantify the mechanisms of solute mixing and dispersion in immiscible two-phase flow, assess how density variations between miscible phases influence solute transport, and use this knowledge to quantify reactive mixing in two-phase flow systems. This interdisciplinary endeavor includes high fidelity numerical simulations of two-phase flow and solute transport, stochastic models of medium heterogeneity, and Eulerian and Lagrangian flow and transport dynamics, new data analysis strategies, and upscaling approaches. MDFT will provide a completely new qualitative and quantitative take on M&D in multiphase systems through the combination of the complimentary skill of researcher and supervisor. Thus, this action is fully in line with the MSCA work program by offering high-quality researcher training, fostering attractive working conditions, and supporting the creation of international and interdisciplinary partnerships.

Mots clés : hydrogeology, mixing, dispersion, porous media, two phase flow, numerical simulation, upscaling, groundwater remediation, hydrogen storage, carbon storage, lamella theory

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 209914.56 €
Projet GNACS (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : SIGNED

This multidisciplinary project bridges differential geometry, optimal control, and numerical analysis, with practical applications in robotic engineering. It introduces a novel approach to path-planning for dynamical control systems on Riemannian manifolds, simplifying many challenges of modern geometric control methods. The central hypothesis is that, under certain conditions, control forces can be integrated into the geometry of the configuration manifold, enabling the trajectories of double-integrator systems to be interpreted as Riemannian geodesics of a modified Riemannian metric. By introducing Gordonian and conformal transformations, the metric is strategically modified to achieve objectives such as trajectory-tracking and obstacle and region avoidance. B-stable modifications of the implicit geodesic Euler method and symplectic geodesic Euler method are constructed on Riemannian manifolds by strategically modifying the curvature through Gordonian transformations. Applications considered throughout the project include the design of trajectory-tracking control schemes for teams of quadrotor UAVs transporting cargo, as well as region avoidance on Riemannian homogeneous spaces.

Mots clés : geometric control, riemannian geometry, geometric integration, optimal control

Participants :
- Université norvégienne de sciences et de technologie (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 251578.56 €
Projet PESTBAN (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : SIGNED

Farm to Fork strategy aims to reduce hazardous pesticide use by fifty percent by 2030 to help achieve a climate neutral Europe but it is still an open question whether potential benefits of the proposed strategy can outweigh its costs. Therefore, it is crucial to examine if eliminating harmful pesticides can provide significant health improvements and to weigh these health benefits against the potential economic costs of adopting safer but less effective plant protection practices. The project's main objective is to examine the impact of hazardous pesticide bans on early-life health and economic outcomes in Türkiye.  PESTBAN will expand the state-of-the-art knowledge on economics of pesticides in several aspects. First, it will contribute to previous studies on pesticides and health by comparing early-life health outcomes within agricultural areas as they switch from hazardous pesticides to safer alternatives. Second, the project will contribute to existing literature on economics of pesticide bans by monetizing the health gains from harmful pesticide bans and comparing these benefits to economic impact of bans on agricultural production areas. The project has the potential to encourage adoption of stricter regulations on hazardous pesticides by highlighting the health benefits of pesticide bans.  Specific aims of the project include (1) data collection on hazardous pesticide use and established bans in Türkiye, agricultural production and crop prices; acquisition of individual health data from national birth registry and national health surveys; (2) empirical analyses to investigate economic and health effects of pesticide cancellations established between 2005 and 2015; (3) implementation of models from soil and water sciences to evaluate the pollution potential of groundwater sources and to provide insights on whether hazardous pesticides can persist in the environment and continue to threaten the public health in surrounding regions long after the imposed bans.

Mots clés : economics of agriculture, infant health

Participants :
- Université Sabancı (Turquie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148478.4 €
Projet Enhanced-DDS (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Cancer treatment by current clinical methods has many side effects, which result from the non-specificity of these methods. Moreover, treatment of some cancers, such as brain tumors, is extremely difficult because the brain barriers (blood-brain barrier (BBB) and blood tumor barrier (BTB)) prevents more than 98% of drugs from entering the brain. The use of stimuli-responsive nanomaterials for cancer therapy is more efficient than conventional ones due to access to targeting tissues, deep molecular targets, lower side effects, and controlled drug release. Mesoporous silica nanoparticles (MSNs) are widely used nanocarrier for drug delivery due to their unique physicochemical properties. However, the lack of consideration of the economic efficiency of MSNs synthesis, their surface modification methods, and the lack of use of physiologically relevant systems to test the efficacy and safety of MSNs, have caused that an effective and definitive cancer treatment method by MSNs has not been provided so far. In this project we aim to solve these problems and make the use of MSNs for therapeutic approaches realistic. The goal of this project is to develop a biosource-derived stimuli-responsive MSN for combined PDT/ chemotherapy of brain tumors to be evaluated in a physiologically relevant human cell-based 3D in vitro brain tumor microfluidic system. This project will be the first to investigate a combination therapeutic agent based on natural products modified with advanced plasma technology and evaluated in a novel human cell-based 3D microfluidic in vitro system that includes the BBB. Outcomes of this project will enhance the existing knowledge and technologies for MSNs’ synthesis, modification, and their cancer treatment performance evaluation, which will yield high-impact journal publications, as well as potential commercial product in the long term.

Mots clés : drug delivery, stimuli responsive nanoparticles, biosources, cancer treatment, surface modification, dielectric barrier discharge plasma, microfluidic device design, organ on a chip, stem cell

Participants :
- Université Sabancı (Turquie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148478.4 €
Projet EDU-MM (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Myanmar, a diverse Southeast Asian nation with numerous ethnic and religious groups, faces socio-political conflicts that significantly affect its socio-economic development, neighboring countries, and the international community. The 2021 coup further impaired all sectors of its system, including education, resulting in millions of children being deprived of access to formal education. Various non-state educational services have emerged to address these gaps and provide alternatives to the junta's system; however, they face challenges in securing recognized qualifications and further learning opportunities for their students. Post-secondary non-state education initiatives are crucial for further learning opportunities for these non-state students who would serve as the change agents for the resilience of the socio-economic well-being of the country. This study, applying convenience sampling and case studies, aims to investigate the typology, challenges, coping strategies, and implications of these non-state post-secondary initiatives in post-2021-coup Myanmar. The study will employ principles of analytic eclecticism, which allows integration of diverse theoretical and academic perspectives to address real-world complexities. This study will be the first of its kind which explores the implications of these initiatives not only in the ethnic minority areas but also in the whole country, including the Bamar-dominated areas. Continuous monitoring and analysis are essential for regional and international stakeholders to comprehend the trajectory of the conflict in Myanmar. The findings from this research will elucidate the education landscape in Myanmar and broader theoretical concepts such as human rights, social agency theory, social mobility, structuralism, institutionalism and conflict studies. It will provide evidence-based policy recommendations for the participating organizations, local and national authorities, and international donors.

Mots clés : myanmar, education, conflicts, social welfare, inequality, rights

Participants :
- Université Palacký (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 191918.16 €
Projet NECTAR (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The project proposes to convert solar energy into hydrogen fuel by utilizing a thermoelectric integrated tandem photoelectrochemical (PEC) system with the main goal of generating a robust, scalable, and competitive solution of solar energy technologies. The project will focus on materials development, rigorous characterization, cell development, and prototyping. We will utilize solution-based techniques to address the urgent need for efficient absorbers for PEC systems via transferable methods for large scale production. We will target cost-effective and abundant materials for all required components without sacrificing their performance. Our proposed system will be the first work on solar driven-overall water splitting utilizing solution processing routes with benign molecular ink for photoabsorber synthesis coupled with earth-abundant and low-cost material cocatalysts. Furthermore, rigorous in-situ characterization will provide an overview of the overall processes involved in PEC reactions which will further guide system design. Finally, a prototype of an efficient and durable PEC cell will be realized.

Mots clés : water splitting, tandem, pec, kesterites, photovoltaics, photochemistry, photocatalysis

Participants :
- Institut de micro-électronique et composants (Belgique) — Coordinator, beneficiary, Recherche, subvention : 216240.0 €
Projet ENSPEC6G (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

6G have already been pronounced even we just met with 5G. Extreme data-rates with extremely low latency envisioned to open path to applications like real-time holographic communications. In the line of technological innovations and developments to increase the wireless data-rates, considerations on energy efficiency have remained silent. This proposed action aims to cover ultra-high data-rate, energy-efficiency, low-latency and low-cost as well as supporting beam-steering capabilities for mobility and multi-users, for the next generation indoor wireless infrastructure. CMOS stands out for low-cost, high yield, reliability, repeatability, and is employed in here within several manufacturing technologies. Sub-terahertz frequencies can be used to increase data-rates with wider bandwidths. Even with the increased bandwidths, spectral efficiency must also be increased for higher data-rates. This contradicts with energy efficiency in conventional wireless transmitters employing higher order modulations such as 16QAM. On the contrary, simple modulations enables more energy efficiency, yet, data-rate is limited due to lower spectral efficiency. Moreover, simple modulations do not require heavy digital signal processing and complex baseband circuitry, hence the latency is lower than higher order modulations. A novel BPSK×BPOOK modulations combination is targeted for increased spectral efficiency and higher data-rates while keeping the complexity minimal and hence increased energy efficiency, with inherently low latency. Phase interpolator circuits are to be deployed here in an unconventional approach that is different than the state-of-the-art to achieve beam-steering. This proposed action, “ENergy- and SPECtrally-Efficient sub-THz Transmitter Array Towards Indoor 6G Infrastructure” (ENSPEC6G) aims to propose a solution for a sustainable future in mind of the trade-offs between economic, environmental, and social objectives for the next generation wireless infrastructure.

Mots clés : ultra high data rate, wireless, energy efficiency, spectral efficiency, sub terahertz, cmos, transmitter, phased array, phase interpolator, modulator, dual polarization, on chip antenna, bpsk, bpook

Participants :
- Université Sabancı (Turquie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148478.4 €