Projet NEUROMECH (Horizon Europe, appel à projets 2024)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

NEUROMECH aims to establish a new generation of skilled, entrepreneurial, and innovative scientific leaders that will integrate the currently isolated fields of mechanobiology and neurodegenerative diseases.  Mechanobiology explores the effects of physical forces on cell physiology. Evidence indicates that key mechanisms of neurodegeneration – cytoskeletal alterations, protein aggregation, protein phase transitions, DNA damage accumulation, and metabolic alterations – can be a consequence and cause of mechanical alterations. Mechanobiology may therefore be a unifying process in a broad spectrum of neurodegenerative diseases, which have rarely been approached from the mechanobiology prospective. NEUROMECH will bridge this gap and address the need for disease modifying therapies focusing on Alzheimer's and Parkinson's disease, frontotemporal dementia, and amyotrophic lateral sclerosis.  NEUROMECH is an international and synergistic network of key scientific experts in mechanobiology and neurodegenerative diseases. Its ambitious research program ranges from atomic force microscopy to in vivo investigations using magnetic resonance imaging. The consortium includes industrial partners and a top European business school to provide training on managerial and strategic skills. These tools will allow Doctoral Candidates to fully understand and navigate both the complex landscape of neurodegenerative diseases research and the value chain of the very different organizations operating in this domain. Overall, NEUROMECH will provide Doctoral Candidates with multidisciplinary, intersectoral training that will enhance their career perspectives in academic and non-academic sectors.


Participants :
- Institut national de la santé et de la recherche médicale (France) — Partner, beneficiary, Recherche, subvention : 314669.16 €
- The blackboard tree (Pays-Bas) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Institut Paul Scherrer (Suisse) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université Johannes-Gutenberg de Mayence (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 290272.32 €
- Université Érasme de Rotterdam (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 305285.76 €
- Université Paris Cité (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Conseil national de la recherche (Italie) — Partner, beneficiary, Recherche, subvention : 281755.08 €
- Organotherapeutics gmbh (Luxembourg) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 288540.0 €
- Single-cell technologies kft (Hongrie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 254904.12 €
- Université du Luxembourg (Luxembourg) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Bocconi (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de L'Aquila (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 563510.16 €
- University College de Londres (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 348738.12 €
- Université de Szeged (Hongrie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €