Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet DarkLife (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

In the last years, human activity has rapidly accelerated the rate of biodiversity loss, compromising the vital goods and services ecosystems provide to sustain well-being, and future economic and social development. The Black Sea Basin is listed among the WWF’s “top priority places” for conservation. Its unique biota, however, is serious threatened by illegal logging, intensive agriculture and unsustainable coastal development. Although the Black Sea Basin biodiversity is reasonably well characterised, many questions about its origin and relevance for present-day European natural heritage remain. The The DarkLife project aims at improving our current knowledge on the origins and diversification of terrestrial invertebrates in the Black Sea basin – a neglected refuge for survival of species during Quaternary glaciations and an important centre of origin and subsequent dispersal of a unique component of European wildlife. To tackle this ambitious goal, I will combine integrative taxonomic research with high-throughput DNA sequencing (HTS) techniques and state of the species distribution modelling (SDM) tools. I will use spiders as a model system organism. I will gain expertise on modern systematic and evolutionary biology research through training in two leading European institutions, the University of Barcelona, the top ranked university in Spain, and the Senckenberg Biodiversity and Climate Research Centre (BiK-F) in Germany. The results of the DarkLife project will help me to reveal the factors and mechanisms that shaped the Black Sea basin unique biodiversity melting pot, unravel its origins and dynamics and, more importantly, predict how global warming may affect its future viability. The training provided by the MSC will help me to secure a scientific position in Bulgaria and become an active player in the development of future conservation policies and sustainability programs my home country.

Mots clés : systematics, evolutionary biology, hight throughput dna sequencing, species distribution modelling, climatic change, conservation biodiversity, wildlife, taxonomy, zoogeography

Participants :
- University of Barcelona (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172932.48 €
Projet WOMAM (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

In the last years, the inclusion of gender perspective in Archaeology has had a strong impact, contributing to a deep transformation of the discipline in several aspects as hypothesis proposal, methodology or interpretation of results. Unlike other European or American countries, in Spain this renovation has not accomplished the same level of development, partly because of the scarcity of funding. Despite growing social interest, there is a major deficit in the knowledge we have about the origin of gender inequality. The way to inequality between men and women took place during the last phases of Prehistory, a period to which we approach mainly by Archaeology. Through this project, we aim to contribute to the advance in this research field, continuing a trajectory already started but from an interdisciplinary methodology which allow us to go further. Specifically, the project focuses on the analysis of gender inequality in Late Prehistory through the study of mobility. Social Anthropology and Ethnography studies poses a link between matrilocal residential patterns and more equality, on one hand, and patrilocal patterns and more inequality, on the other. It suggests that women mobility constitutes a relevant factor in the analysis of sexual inequality, opening the door to the proposal of hypothesis that connect such aspect to the origin of gender inequality in Prehistory. At the same time, in Archaeology, the study of mobility through strontium and oxygen stable isotopes allow us to approach to residential patterns in the past. Our aim is to combine both Social Anthropology and Archaeology in the study of Neolithic, Copper and Bronze Age, key periods in the study of social complexity, and to define better when and why women and men became unequal.


Participants :
- Universidad de Sevilla (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175099.2 €
- University of Iowa (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet OPSVIO (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Statut du projet : CLOSED

In the nature, we observe disbalance between the matter and antimatter, which can be explained by requiring of CP symmetry breaking. This was already observed in the quark sector, but the level of violation was not enough to explain the matter-antimatter asymmetry. Recent experiment involving neutrino oscillations reported the indication of CP violation in the leptonic sector. Ortho-Positronium (spin 1), a purely leptonic system, has very well-defined C and P properties, what makes it suitable for probing the CP ant CPT symmetries by constructing angular correlations between the polarization direction of positronium spin and the momentum or the polarization vector one of 3 gammas. Any deviation of the angular correlation amplitudes from zero would indicate discovery of a new physics. Within this action we propose to perform high precision measurement of CP amplitude and improve the precision level for one order of magnitude compared to the state-of-art results. The data acquisition system will be based on fast pulse digitizers, what will increase the rate and the amount of collected data, but will also increase the complexity of the data analysis. Data collected in this measurement will also contain information on two CPT amplitudes. We will determine both, and one of them will be determined for the first time. Since no suitable polarimeter for annihilation gamma rays exists at the moment, we will study polarization sensitivity of a single-layer Compton polarimeter based on 8x8 GaGG(Ce) crystal array, which will be read out by a matching SiPM array.

Mots clés : ortho positronium decay, cp violation, cpt violation, polarization measurement

Participants :
- University of Zagreb (Croatie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 147463.68 €
Projet NewBorN (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

In the past decade, photoredox catalysis has emerged as a tremendously versatile process to generate reactive radical species in organic synthesis under very mild conditions. Meanwhile, the host group have developed a suite of transformations exploiting the fundamental chemistry of boron, many of which involve 1,2-metallate rearrangement of boronate complexes. In this proposal, we propose to merge the N-centred radicals generated through photoredox catalysis and 1,2-metallate rearrangements of vinyl boronate complexes to create an efficient new strategy for organic synthesis, which will lead to a novel three component reaction where new C–C and C–N bonds are formed in one-pot, providing a new synthetic avenue for the preparation of β-amino boronic esters. Moreover, intramolecular radical cyclizations followed by oxidative 1,2-migration will enable the stereoselective synthesis of diversely functionalized cyclic amines. The scope of these processes will be carefully investigated, and mechanistic studies will be carried out using advanced physical/chemical methods. These novel methodologies not only benefit from the formation of highly functionalized products bearing both synthetically versatile boronic ester and amino moieties, but also lay solid foundations for the development of this new field. Based on the significant antibacterial activity against Mycobacterium tuberculosis of β-amino boronic acids, a preliminary test of the biological activities of compounds obtained throughout the proposed research (both cyclic and linear β-amino-boronic acids) will be carried out in collaboration with AstraZeneca. By combining two major fields of endeavour, new chemistry will emerge with unique structures harbouring novel properties for exploitation. Furthermore this project will enable significant knowledge transfer between host and researcher, while forging new academic networks within the scientific community.

Mots clés : photocatalysis, 2 metallate rearrangement, radical amination, amino boronic ester

Participants :
- University of Bristol (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet NanoRNA_PC (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

In the past three decades, nanomedicine has emerged as a promising strategy in cancer treatment and has led to numerous proposed drug delivery systems. Nanoparticles aim to improve selectivity towards cancer cells while reducing off-target effects and toxicity towards normal cells. Among these systems, self-assembled RNA nanoparticles have been of great interest for drug delivery, because of their low cost, high yielding assembly and retained functionality. Yet, challenges such as poor nuclease resistance, biodistribution and cellular delivery remains to be addressed, to fully propels these structures towards clinical applications. To optimize these systems, there is a huge need to understand precisely their interactions with biological components. In particular, upon injection in vivo, it is known that serum proteins adsorb on nanoparticles. The composition of this so-called protein-corona on RNA particles remains fully unexplored. Herein, I propose to characterize the protein corona on RNA nanoparticles using state-of-the-art methodologies (proteomics, super-resolution microscopy, SELEX), as well as understand the role the corona on the fate of RNA structures. I will engineer the protein corona to improve biological outcomes of RNA particles, previously developed by Sixfold Bioscience Ltd. Overall, the project aims at providing tools and rules for rational engineering of the protein corona. In the long term, the project, grouping experts in industry and in academia, aims towards the development of a preclinical candidate, as well as answering fundamental questions on nanoparticles delivery.

Mots clés : rna nanotechnology, rna structures, nanostructures, gene therapy, cell therapy, protein corona, bio engineering, aptamers, selex, serum proteins

Participants :
- Sixfold bioscience ltd (Royaume-Uni) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 212933.76 €
Projet GlobaLISe (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : CLOSED

In the post-Bretton Woods world economy, global value chains (GVC) have become the principal pipelines not only of trade, but also of capital and technology flows, with a decisive impact on the industrial structure of local economies and the technological dynamics of their innovation systems. The proposed project aims to investigate from an empirical, theoretical and normative perspective this impact, as well as its macroeconomic repercussions in terms of productivity, growth, employment, income distribution and the core-periphery technological divide. It will also examine the industrial policies needed to mitigate the technology gaps and to enhance the value capture capacities of peripheral innovation systems by ‘upgrading’ within GVCs, against the backdrop of the financial crisis. At the empirical level, the project will focus on GVCs of knowledge-based manufacturing industries in crisis-afflicted Southern European economies. It will employ advanced statistical, computational and analytical methods at different geographical scales, ranging from econometric to social network analysis, agent-based, and stock-flow consistent modelling. At the theoretical level, it aspires to combine evolutionary, institutionalist, Schumpeterian and (post) Keynesian economic theories under a ‘systemic’ research programme on the crossroads of international economics, economic geography, innovation economics, theory of the firm, industrial organisation, and political economy of development. At the normative level, it will have significant implications for industrial, RTDI, trade, and regional development policies. This highly topical project aims to frame the post-crisis EU policy discourse on the future of the ERA, the Innovation Union, Europe 2020 growth strategy, and the ‘European investment plan’, as well as related national policy discourses. It is designed to boost the researcher’s career and to consolidate his expertise and research skills through high-quality training.

Mots clés : global value chains, innovation systems, technology gap, trade in value added, global production network, technology diffusion

Participants :
- Centre for Planning and Economic Research (Grèce) — Coordinator, beneficiary, Autres, subvention : 152653.2 €
Projet Invisibilia (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

In the project “Tracing the Invisible. Old Norse and Latin in Medieval Manuscripts (INVISIBILIA)”, I propose to investigate bilingualism in medieval Northern Europe by focussing on the most popular media of the time: manuscripts. I will trace their Latin components, which have mostly been neglected in research until the present day, and make them accessible to the scientific community digitally, thus providing essential texts and finding aids for the Latin sections. I will analyse the interaction of the Latin with the Old Norse texts. By relating them to the production, dissemination and use of manuscripts by people from different social backgrounds, I will give a deep insight into the European literacy of medieval Icelanders and Norwegians in the time span ca. 1100 – ca. 1500. INVISIBILIA will focus on the manuscripts held in the Arnamagnaean Collections in Copenhagen and Reykjavik, which represent approx. 90 % of the total number of Old Norse codices. Any exemplar containing both Old Norse and Latin as clearly distinct entities will contribute to the corpus of the study, about 400 manuscripts in total. I will approach this corpus according to three major research objectives, namely a full catalogue of the Latin entities, a comprehensive multi-level edition, and a comparative study. The results of the three research objectives will be integrated in an enhanced publication, realising the latest developments in Digital Humanities. This open access, on-line website will exchange data with existing scientific databases and make it possible for other scholars to collaborate actively. By spanning the borders between Traditional and Material Philology, Cataloguing and Editing, and Traditional and Digital Humanities, INVISIBILIA reaches out to scholars of medieval Scandinavia and Medieval Latin alike. The research results will be directly comparable to other pre-modern bilingual literary systems and challenge the isolationism still found in Old Norse-Icelandic scholarship.

Mots clés : manuscript studies, bilingualism, digital editions

Participants :
- University of Copenhagen (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 200194.8 €
Projet QuESt (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Physics
Statut du projet : CLOSED

In the quest for solar cell technologies, organic photovoltaics (OPVs) are playing a leading role as a potentially cost-effective and clean solution. Thus, much research has been devoted into increasing power conversion efficiencies (PCE), currently ~10% by optimising material properties at the different steps involved in the conversion of light into charge. There is evidence that charge delocalization and hot charge transfer (CT) states facilitate charge separation at the electron donor/acceptor interface. State-of-the-art OPVs already exhibit very high (>90%) internal quantum efficiencies (IQE). However, PCE relies not only on high IQE but also on minimizing energy loses (e.g. exciton relaxation) and avoiding charge recombination. A possible strategy to increase PCE is to find ways to optimise charge separation that allow simultaneously for high quantum efficiencies and architectures with longer exciton diffusion lengths or lower charge recombination rates. In QuESt we will investigate how to enhance OPV functionality by the emerging approach of modifying material properties through the hybridization of matter and photon states under strong light matter coupling. In particular, the aim of this project is to modify charge separation and eventually PCE in OPVs by engineering strong coupling between IR molecular vibrations and an optical cavity mode. We will develop a theoretical framework to describe the energy structure and charge dynamics in OPVs under strong vibrational coupling that will be benchmarked with non-linear spectroscopy experiments.

Mots clés : strong light matter coupling, ir vibrations, open quantum systems, exciton and charge transport

Participants :
- Princeton University (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Scuola Internazionale Superiore di Studi Avanzati (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 262269.0 €
Projet PARENT_CITIZENS (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

In the wake of economic, climate, and violent crises throughout the Mediterranean region, Europe has recorded more asylum seekers and immigrants during the past decade than ever before. As these new populations seek to integrate into European society, the following questions arise: are there sufficient institutional sites and resources to civically incorporate these incoming individuals and families? More importantly, what are the appropriate and practically effective institutions to build shared values of tolerance, respect, and citizenship? The purpose of this interdisciplinary project is to investigate the public institution most directly responsible for civic education, public schools, in three of the highest immigrant destination countries in Europe: Italy, Spain, and France. Yet while most European wide civic education initiatives focus on school children, the focus of this study is parent participation on parent councils (assemblee genitori, asociación de padres, conseil des parents d'élèves) at schools. In many nation states throughout Europe, parents have the right and expectation to participate at schools through legally codified parent councils, yet they remain little understood as a vehicle for productive civic integration. This absence in the scholarly literature and European institutional initiatives is surprising given the established finding that schools are the primary public institution where immigrants interface with others and participate civically. In sum, parent councils at public schools are uniquely situated as a civic educational institution and remain nearly absent from citizenship education initiatives in Europe. In an effort to illuminate the viability of parent councils for civic integration, this study utilizes a mixed-method framework to build a conceptual understanding through qualitative methods in the first phases of research which inform a representative survey of parent members in the final phase of the study.

Mots clés : citizenship, parent councils, schools, adult civic education, immigrant citizenship education, civic integration, parent participation in schools

Participants :
- Ca' Foscari University of Venice (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183473.28 €
Projet Giving Land Back (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

In the wake of violence, dispossession, and regime change, giving back land offers a critical opportunity to address historic injustice. Yet seeking to reconcile the past invites conflicts over material distribution and political inclusion in the nation’s future. This project investigates land restitution in Myanmar, a formerly authoritarian, predominantly agrarian nation currently undergoing a rapid, public and bumpy transition towards democracy. Building on over five years of research on land reform and agrarian change in Myanmar, I ask how the new government’s efforts to return land are taking shape, and what these processes mean for the nation’s future and for the place of rural land in global development. Under the guidance of Prof. Christian Lund, a leading scholar on the production of property and citizenship in developing societies, this project will contribute new empirical analysis, conceptual insights, and policy recommendations to inform urgent debates on rural transformation, democratization and social inequality.

Mots clés : land, property, citizenship, rural transformation, agriculture, development, political systems and institutions, governance, state formation, conflict and conflict resolution, myanmar, ethnography

Participants :
- University of Copenhagen (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 207312.0 €
Projet DELTAS (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

In this project I plan to investigate by means of numerical simulations the dynamics and rheology of low-density equilibrium gels made of limited-valence building blocks. I will start with simple toy models of patchy particles and then add complexity in the form of inner degrees of freedom by investigating systems that undergo a hierarchical self-assembly process. Examples of such systems are recently synthesised DNA constructs and telechelic star polymers. The novelty of DELTAS lies in the focus put on the role of the internal flexibility as a tool to tune the dynamics and the rheology of equilibrium gels. Indeed, the possibility of fine-tuning the structure of these materials lend themselves well to many applications, ranging from medicine to material science. The project goes one step further by proposing to investigate the kinetics, dynamics and mechanical properties of these systems in the framework of (flexible) patchy systems. The usage of simple toy models will grant a better understanding of the phenomenology of these systems. In addition, the realistic systems I plan to investigate will, on one hand, establish a stronger link between theory and numerical simulations and experiments and, on the other hand, provide a testing ground for the results obtained with toy models.

Mots clés : dynamics, rheology, gels, physical gels, hydrodynamics, patchy particles, colloids, patchy colloids, polymers

Participants :
- University of Oxford (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €