Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet Polar2MidLat (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Cold air outbreaks are a typical feature of the mid-latitude climate during the cold season. Their relevance relies on the threat to life caused by the long-lasting periods with abnormally low temperatures as well as on the potential of damage to crops and the occurrence of high-impact weather events such as heavy snow and low visibility during blizzards. Previous studies have documented the linkages between climate variability at high latitudes with that at mid-latitudes mainly through modulation of the storm tracks, jet streams and patterns of stationary waves which promote blocking events. The role of other components of the climate system, like sea ice, is much less understood and remains an open question. This becomes even more challenging under the current conditions of fast sea ice reduction in the Arctic and the significant trends observed in sea ice around Antarctica, which leads to an increase in uncertainty in the area of sub-seasonal to interannual climate predictions as well as for climate projections for the coming decades. Furthermore, significant biases currently exist in the representation of sea ice in state-of-the-art climate model simulations. The main objective of this proposal is to analyze the physical mechanisms linking variability at high latitudes (including that of sea ice) with climate variability at mid-latitudes. Special focus will be driven onto the mechanisms promoting cold snaps at mid-latitudes and on their variability. To this aim, this project will make use of a data set of very-high-resolution coupled global climate model simulations (at around 10 km) which is expected to bring significant improvements to the representation of sea ice as well as to its linkages with other components of the climate system. Outcomes of this project are expected to become useful for decision makers and stakeholders, as well as to researchers working in the field of climate predictions and projections.

Mots clés : cold air outbreaks polar regions sea ice global warming climate dynamics

Participants :
- Organisation des Nations unies pour l'éducation, la science et la culture (France) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université d'Exeter (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université polytechnique de Catalogne (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet ME-COMPLEX (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The electrospray ionization with mass spectrometry detection (ESI-MS) has been widely used to study biomolecules, low molecular weight compounds, and noncovalent complexes. Ion mobility spectrometry (IMS), capable of separating ions with the same m/z but varying sizes and shapes in the gaseous phase, has been recently hyphenated with the ESI-MS to conduct fundamental and applied research. The overall objective of this proposal is to generate new knowledge on the biological function and chemical characteristics of siderophore-metal complexes (SMCs) under real conditions such as seawater and rhizosphere by harnessing in-source activation (ISA) and cutting-edge ESI-IM-MS technology. To this end, the experimental investigations will involve varying ESI parameters, such as ESI and ISA voltages and drying gas temperature, and solution conditions, e.g. pH, solvent type, ionic strength, and matrix, to investigate stability and competitivity, hydrolysis, hydrogen-deuterium exchange behavior, and fragmentation patterns of SMCs plus finding the binding site locations of siderophores to metal ions in SMCs. The proposed project will also include experimental and theoretical calculations of collision cross-section (CCS) values and thermodynamic studies via quantum-mechanical methods, i.e. density functional theory to rationalize the experimental observations. The obtained CCS values will allow us to derive additional structural and spatial information on the investigated SMCs. The proposed project is multidisciplinary in nature as it integrates analytical chemistry, soil/plant research, environmental science, physical chemistry, and quantum mechanics. Two-way knowledge transfer in this project ensures the transfer of the candidate's expertise in the areas of sample preparation, flow systems, and 3D-printing technology to the host institution and training of the candidate in advanced analytical chemistry techniques to enhance his employability and career development.

Mots clés : siderophore metal complexes, electrospray ionization, in source activation, ion mobility spectrometry, mass spectrometry, stability and competitivity investigations, rhizosphere, seawater

Participants :
- Universität für Bodenkultur. Vienne (Autriche) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183600.96 €
Projet Fire-Tools (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The use of fire is an element that characterizes the genus homo and one of the technologies that more substantially modifies prehistoric life systems. Nevertheless, the oldest evidences of fire are often more controversial and difficult to identify. The Fire-Tools project address the habitual use of fire in two peninsular archaeological sites with indirect evidence of fire in their levels and dated between the 400-300ky: Sima del Elefante (Atapuerca, Spain) and La Cansaladeta (La Riba, Spain). This geographical and chronological range has been carefully selected: the Iberian Peninsula provides the ecological conditions (wood availability) for the use of fire throughout the Pleistocene, and the habitual use of fire is stipulated as the most accepted hypothesis during this period. Fire-Tools Project aims to apply a cross-cutting approach integrating archaeobotanical (Phytoliths) and chemical analytical (Polycyclic Aromatic Hydrocarbons) procedures in these two case studies to improve the analytical capacity to identify and characterize the pyroarchaeological record with low visibility. Furthermore, the project will create a widen and complete modern reference collection of phytoliths from woody plants, as an important analytical tool to address the pyroarchaeological record in Paleolithic sites. Additionally, the Fire-Tools project will evaluate the integration between the analysis of archaeobotanical microrremains and chemical elements with the archaeological data available from each archaeological site. The expected results of the methodological proposal seek to be of further application in other archaeological and chronocultural contexts with the presence of fire. In sum, the results of this project will allow knowing the relationship that the hominids of the Middle Pleistocene had with fire in the context of Iberia, validating a methodological and analytical approach to study the fire record across Prehistory.

Mots clés : middle pleistocene archaeological fire related remains archaeobotany phytoliths modern reference collection archaeochemistry polycyclic aromatic hydrocarbons pahs pyroarchaeology

Participants :
- Université de Leyde (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 203464.32 €
- Université du Pays basque (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet MiMaPro (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

The substantial amount of agro-industrial by-products, such as rapeseed cake, poses an environmental concern in the EU. MiMaPro is a multidisciplinary project that aims to valorise rapeseed cake by modifying the structure of rapeseed cake protein (RCP) and enhancing its value as a plant protein beverage, both in the laboratory and pilot-scales. This strategy aligns with the EU's Circular Economy Action Plan and meets consumer demand for plant-based diets. Novel approaches will address techno-functional challenges, including low solubility and emulsification of RCP: a) Microreactor-Assisted Maillard: MiMaPro's originality lies in improving the techno-functional properties of RCP by employing a microreactor-assisted Maillard reaction to create conjugated RCP. A microreactor will be used to accelerate the reaction while managing the progression to advanced glycation, finally improving solubility and emulsification. b) Spray Drying: MiMaPro will employ optimised spray drying (as a scalable process) to produce Maillard conjugated RCP powders with minimal variation from freeze-dried powder. c) Emulsion Creation: Conjugated RCP will be partially blended with pea protein to create a hybrid protein with a balanced amino acid profile. An emulsion stabilised by this blended conjugated RCP-pea protein will be prepared, followed by kinetic stability determination and bioavailability assessment of emulsion-loaded vitamin D3. d) Upscaling and Prototype Generation: MiMaPro will scale up the microreactor and spray drying based on the knowledge gained from steps a-c to produce a plant protein emulsion beverage prototype. The majority of MiMaPro will be conducted at UL (host). The fellow will participate in a secondment at Ulster University to study vitamin D3 bioavailability and undertake an industry placement at CPI to upscale the process and develop a prototype. The fellow will also receive a comprehensive training plan that includes both scientific and transferrable skills.

Mots clés : maillard reaction, microreactor, plant proteins, rapeseed cake protein, emulsion beverage

Participants :
- Université de Limerick (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 252728.64 €
- Université d'Ulster (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet FLAPS (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

The first vertebrate animals were jawless marine organisms which appeared in the fossil record over 500 million years ago. These lineages diversified and eventually crept ashore leading to further evolutionary divergence and become the charismatic living groups. The evolution of limbs in one lineage of vertebrates set the stage for these vertebrates to colonize landmasses around 320 million years ago. The water-terrestrial transition included some chalenges, such as air breathing, sustain the body weight dealing with gravity force and avoid the dehydration. On land, vertebrates radiated evolutionarily into many of the vacant niches. Well-adapted on terrestrial enviroment was the time to the aerial conquest. The extant flying vertebrates are the birds and bats, but pterosaurs were the first vertebrates to rule Mesozoic skies. These three groups evolved convergently to power their wings and increase the metabolic capacity during the flight. The origin of vertebrate flight is still unclear there is a dicothomy debate discussing whether it evolved from glidind or flapping ancestors. There are discordancies between the experts, some studies indicated pterosaurs as ground-based at hatchling and others suggested a powered flight in early life for these flying reptiles. Herein, this project will create a new method to explore the origin of the flight in vertebrates investigating the metabolic challenges of the pionner group to accomplish this ability: the archosaurs.

Mots clés : birds metabolic rates powered flight pterosaurs vertebrates

Participants :
- Centre national de la recherche scientifique (France) — Coordinator, beneficiary, Recherche, subvention : 195914.88 €
Projet MANOS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

This research intends to explore the discourses and social dynamics constructed on social media by manosphere groups, particularly Pickup Artist, InCel, and MGTOW communities, as well as its roots and if these discourses are successfully imported to the Portuguese and the Irish contexts, comparing both. The study will focus on the gender identity narratives created by men who identify with these groups or singular influencers with similar discourses. Pickup Artists and MGTOWs share the red pill theory which is characterized by a rejection of “the mainstream beliefs around gender”, i.e., the views of liberal feminists whom they believe are marginalizing men. To deal with it, they advocate for individual self-improvement and reject political correctness, and INCELs use the term "black pill" to describe the belief that there is no hope for them to have a romantic/sexual relationship, which can lead to radicalisation and support for violence against women. The main goal of this research project is to examine the construction of narratives about gender in Portuguese and Irish communities of men online; to explore how these communities represent and construct their identity, often through discourses of anti-feminism and misogyny, and how these representations vary across social media platforms and geographical contexts. MANOS will be informed by Critical Theory (Discourse, Narrative, Gender & Media Studies). The project will use a mixed-method approach that combines systematic literature review, critical discourse analysis & digital ethnography (non-participant observation, in-depth interviews & focus groups) to analyse the data collected from both online & offline environments. The research will ultimately identify and develop strategies to counteract the negative effects of these communities, promote gender equality, and the prevention of misogynistic violence by informing public educational policies about internet usage.

Mots clés : masculinities, online communities, anti feminism misogyny sexual violence

Participants :
- Cuadernos pagu (Brésil) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- The men's development network company limited by guarantee (Irlande) — Partner, associated partner, Autres, subvention : 0.0 €
- Université de la ville de Dublin (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 249618.0 €
- Université de Coimbra (Portugal) — Partner, associated partner, Recherche, subvention : 0.0 €
Projet NONCO-MICROTIS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

NONCO-MICROTIS will combine new findings in long non-coding RNA (lncRNA) biology with cutting edge research to uncover innovative therapeutic opportunities for the treatment of lung cancer, one of the most prevalent and deadliest types of cancer worldwide. Current treatments which are often insufficient, include the use of chemotherapy and radiation that induces tumor cell arrest. This process termed as therapy-induced senescence (TIS) has been considered a positive outcome for cancer therapy. However, there is evidence that TIS can be reversible leading to an aggressive phenotype and disease relapse. The low percentage of senescent cells in the tumor together with the lack of specific markers senescence senescence has prevented the development of methods to identify and target this population of cells. I will exploit the highly specific expression patterns of lncRNAs by tailored single cell methods to identify therapy-induced senescent cells and their relationship with the tumor microenvironment. Further, NONCO-MICROTIS will investigate the senescence-related roles of small peptides produced by TIS-lncRNAs to be exploited for the targeting of these singular cells within lung tumors. Altogether my study will define a new senescence signature using specific lncRNAs that will help to identify senescent cells and will provide information on how these cells impact the neighbouring populations. Moreover, it will uncover mechanistic roles of micropeptides in the regulation and targeting of senescent cells and will provide the basis for the use of micropeptides as therapeutic targets. NONCO-MICROTIS will combine cutting-edge techniques in transcriptomics and molecular and cellular biology techniques resulting in an original, multidisciplinary project with high potential for ground-breaking findings. Furthermore, it will allow me to reach the level of professional maturity needed to become an independent researcher.

Mots clés : long non coding rna, micropeptides, therapy induced senescence, lung cancer, senescence associated secretory phenotype, single cell rnaseq spatial transcriptomics

Participants :
- Université de Navarre (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet POT.PUDIN (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

POT.PUDIN aims to analyse the use of ceramic vessels to trace culinary practices and the ingredients used in ancient societies. The project proposes a multi-proxy approach that combines morphological and typological analysis, traceology, and botanical and biomolecular techniques. Initially, a workflow will be developed to maximise the effectiveness of these methods and ensure their feasibility. This workflow will then be applied and tested on an assemblage of Chalcolithic pottery from the Los Millares site (Almería, SE Iberian Peninsula). The Los Millares pottery assemblage was selected for its scientific significance and the excellent preservation of its ceramics. Dating from 3300 to 2200 cal BC, Los Millares is a key site for understanding the Chalcolithic in southwestern Europe, providing early evidence of copper metallurgy, defensive fortifications, socially differentiated households, and monumental burials. These elements indicate the emergence of social inequality in the western Mediterranean, making Los Millares an ideal case study for testing and refining the proposed methodological framework. The ultimate goal of this project is to better understand ancient diets and foodways through an integrated study of pottery use. Moreover, this comprehensive protocol could be applied to other time periods and archaeological contexts.

Mots clés : chalcolithic culinary practices foodways traceology use wear analysis organic residue analysis microbotanical analysis foodcrusts

Participants :
- Université autonome de Barcelone (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Paris Nanterre (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 226420.56 €
- Université du Pays basque (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet CavityMag (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

To further increase performance and reduce energy consumption in technological devices, a new paradigm is needed exploiting quantum mechanical phenomena. An attractive route to enter this paradigm is by interfacing light and magnetic excitations in new optomagnetic devices, which ensures processing frequencies comparable with electronics and hold great promise for future memory, spintronics and quantum computing devices. This, however, requires a deeper understanding of strongly coupled light-matter systems and the interplay between magnetic, electronic, photonic and lattice excitations. A promising platform to explore exotic magnetic phenomena is magnetic van der Waals (vdW) materials, since the competition of anisotropy, quantum fluctuations and spin-orbit coupling make these materials prime candidates to host such states and susceptible to material engineering techniques. This can be exploited in cavity quantum electrodynamics (c-QED) and Moiré engineering to control the magnetic state. By combining c-QED with Moiré engineering, the goal of CavityMag is to construct schemes to control the magnetic state of vdW materials and to induce exotic magnetic phases. This will be achieved by developing state-of-the-art computational tools based on quantum electrodynamical density functional theory (QED-DFT) in combination with effective spin-photon models. This computational framework will be used to perform a systematic study of light-induced magnetic phases in twisted vdW materials, to gain a deeper understanding of how microscopic magnetic interactions can be modified, and to establish concrete protocols to control the macroscopic magnetic state. It will also be used to guide experimental efforts by identifying candidate materials and parameter regimes likely to host exotic states of great promise for the construction of new high performance and energy efficient technological devices.

Mots clés : exotic magnetic states, cavity quantum electrodynamics, moir engineering, magnetic van der waals heterostructures, quantum electrodynamical density functional theory qed dft

Participants :
- Université du Pays basque (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet NEOPLASTICS (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Petroleum-derived plastics produce greenhouse gas emissions (GHGs), the primary cause of climate change, at every single stage of their life cycle. On the contrary, plant biomass is produced via photosynthesis, which involves the transformation of carbon dioxide (one of the GHGs), water, and light into chemical bonds. Therefore, using plant biomass to produce bioplastics removes carbon dioxide from the atmosphere and keeps it stored throughout the product's useful life. Therefore, NEOPLASTICS aims to valorize highly available, low-cost, and non-edible lignocellulosic and non-lignocellulosic vegetable waste to prepare bioplastics that represent an alternative to the traditionally used petroleum-derived polymers for agricultural and packaging applications. Specifically, this project will study the role of natural deep eutectic solvents (NADES) as facilitators for transforming biomass into bioplastics. These compounds are gaining importance as solvents for vegetable waste valorization. They are usually used for biomass fractionation, and only a few recent works have reported their use in transforming natural polymers into bioplastics by acting either as solvents or as plasticizers. These researches represent only a starting point for what it is possible to do with these innovative solvents, whose main advantage is that it is possible to tune their physicochemical properties by varying the nature and ratio of their constituents, which in turn can lead to a wide range of materials properties for different applications. The project introduced here is highly ambitious. It will not only provide advantages such as zero waste generation, contribution to the circular economy, and a low carbon footprint manufacturing process, but it will also boost the career of the experienced researcher and enrich the knowledge and experiences of both the researcher and the host institution, impacting positively on the scientific community, the civil society, and the business sector.

Mots clés : bioplastics, vegetable waste valorization, natural deep eutectic solvents

Participants :
- Université du Pays basque (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €