Projet SHIFT (Horizon 2020, appel à projets 2020)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : SIGNED

Shaping Innovative Products for Sustainable Tissue Engineering Strategies - SHIFT is the follow up of MSCA-RISE REMIX (GA 778078). While REMIX researched and confirmed the potential of natural origin material such as silk proteins, collagen, keratin and marine organism-derived polymers for use in Tissue Engineering and Regenerative Medicine, SHIFT aims to take the research a step forward and design innovative natural-based, scalable constructs that enhance angiogenesis for the treatment of widespread chronic pathologies, such as large defect in bone and cartilage and the treatment of chronic wounds (ex. diabetic ulcer). Prototypes will be fabricated considering scalability, costs, regulatory issues. Multiple strategies will be used to achieve this aim: - pre-assessment of the regulative framework for TERM products and close collaboration with the industry; - fabrication in accordance with current GMP and ISO quality management Systems-requirements - standardization of the protocols for purification of raw materials from the waste of textile and food industry for the production of these prototypes, using medical-grade, commercially-available raw materials as benchmark. This may lead to the opening of a new opportunity for re-using industrial waste which is currently disposed of. - application of the principles of Green Chemistry to reduce the environmental impact of the research and production of the prototypes. An extensive training program will be offered to ESRs to set the best conditions for successful performance. The program will be offered through summer schools and online seminars and will cover a variety of topics related to TERM, technologies, regulations for product development. A special highlight will be devoted to product-development, spin-off, venture capitals, to provide junior researchers with knowledge and skills that may allow them to become profiles capable to successfully transfer ideas and innovations from academia to the industry.

Mots clés : tissue engineering, regenerative medicine, product design, green chemistry, wound healing, bench to bedside, biotechnology, bone, cartilage

Participants :
- University of Sydney (Australie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Chulalongkorn University (Thaïlande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Trento (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 391000.0 €
- Mongolian University of Science and Technology (Mongolie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Birmingham (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 257600.0 €
- Jeonbuk National University (Corée du Sud) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University Kebangsaan Malaysia Medical Centre (Malaisie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Minho (Portugal) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 262200.0 €