Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet SPINIP (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Wearable healthcare devices have disrupted health monitoring with personalized medical diagnostics and real-time data collection. An essential component of such devices are high-performance near-infrared (NIR) photodetectors, which facilitate the non-invasive measurement of vital signs and physiological parameters such as blood oxygenation, heart rate, and pulse rate. Significant progress has been made in exploring functional materials for self-powered NIR photodetectors on rigid substrates. However, the development of flexible self-powered NIR photodetectors and their integration into wearable device applications are largely overlooked in the literature. In SPINIP, we aim to develop efficient and stable flexible NIR photodetectors operating in self-powered mode (or zero bias) based on non-toxic and cost-effective semiconductors tailored for seamless integration into wearable healthcare devices. In particular, we will leverage eco-friendly tin-based perovskite-inspired materials (PIMs), starting from A2SnI6, owing to their broadband photodetection from UV-visible-NIR regions, good air stability, and low-temperature solution processing. The mechanical flexibility of photodetectors is a paramount feature, enabling seamless adherence to various surfaces and conforming to the dynamic movements of the human body. The mechanical flexibility of the device will be investigated via in-situ nanoindentation in FE-SEM. To ensure flexibility, we will perform thorough composition engineering of photoactive PIMs films and explore the synergetic effects of polymer scaffolds and hybrid annealing. The performance of NIR photodetectors will be enhanced by understanding the defect chemistry of PIMs, the charge transport within the device components, and the device physics. The reliability of the photodetectors will be verified in different conditions (environmental, thermal, and mechanical) and will be improved by reducing the ion migration and device engineering approaches.

Mots clés : flexible self powered nir photodetector, lead free perovskite inspired materials pims , photophysics, nanomechanical properties, device reliability, wearable healthcare devices

Participants :
- Université de Tampere (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 215534.4 €
Projet AMELIA (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

A UN Sustainable Development Goal is to ensure inclusive and equitable quality education and promote lifelong learning opportunities for all. The project results contribute to improving the future of education for all and have direct scientific, societal, and technological impacts. Current education solutions are limited to a one-size-fits-all paradigm, unable to support diverse learning needs, and contribute to learning exclusion and gender inequality. State-of-the-art (SOA): Game-based learning environments (GBLEs) bring to bear capabilities that not only shatter physical barriers to education via digital learning, but game mechanics built into GBLEs can be customized and adapted to support diverse learning needs. Game mechanics are important because they sustain learners’ engagement and interest in learning activities, which elicit cognitive processes that water the seeds of learning. Still, more research is needed to develop adaptive game mechanics to support diverse learning needs. The mission of this research is to study interactions between game mechanics and emotions as a non-linear dynamical system and observe the impact of such interactions between diverse learners’ cognition and learning outcomes with GBLEs. In this European Fellowship titled, emotionAl Modelling to Enhance Learning In gAmes (AMELIA), we propose to conduct a mixed multimodal methods study to observe relations between game mechanic interactions and in-game emotions, cognition, and learning outcomes by collecting multiple data channels ranging from think-aloud recordings to neurofunctional measures between gender dimensions. AMELIA will be carried out at Tampere University (host) with supervisor Kristian Kiili and co-supervisor Manuel Ninaus (secondment) at the University of Graz. AMELIA is implemented in collaboration with an international game company called Psyon Games.

Mots clés : game based learning environments, instructional design, complex systems, multimodal data

Participants :
- Université de Graz (Autriche) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Psyon games oy (Finlande) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Tampere (Finlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 249618.0 €
Projet EPIC (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Per- and polyfluoroalkyl substances (PFASs) are emerging environmental contaminants which are highly persistent in the environment with multiple hazardous properties including immunomodulation/immunotoxic potency. Human exposure to PFASs has been associated with various immune-mediated diseases and outcomes. Recently the European Chemicals Agency (ECHA) called for a gradual ban of over 10,000 PFAS compounds in Europe. As concerns grow about the persistence and toxicity of PFAS, the market has shifted towards new PFAS alternatives, however, little is known about the potential risks of these newer chemicals. PFASs have now widely been replaced in many consumer products with PFASs with longer carbon-chains, like perfluoroundecanoic acid (PFUnDA). Rising exposure levels of PFUnDA has been already observed and it was reported previously to have negative effect on the immune system in vitro and in vivo. Blood plasma transports mRNA that modulate immune responses and also extracellular vesicles (EVs) that play key role in intercellular communicationthat and can transport biologically relevant cargo, including microRNAs (miRNAs), and may partly mediate the effects of pollutants on the immune system. This project aims to determine how new PFAS alternatives affect the immune system in long term exposure. To fully understand the mechanisms and to address the multifaceted nature of chemical induced immunotoxicity, the study focuses on changes of key mRNA biomarkers related to the immune system and on the EV-miRNA cargo of extracellular vesicles in long term PFUnDA exposure. Our goal is to develop a multi-biomarker palette identifying key mRNAs and EV-miRNAs in zebrafish to screen novel chemicals for their immunotoxic potency, that is high throughput, quick and easily measured from blood.

Mots clés : pfas, pfunda, immunotoxicology, extracellular vesicles, mrna, ev mirna, zebrafish

Participants :
- Université Masaryk (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166278.72 €
Projet CaMeRoofs (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

One of the most fascinating aspects of medieval churches are the complex wooden frames of the roofs and the ceilings or vaults that dominate the interior. Cataloguing Medieval Roofs (CaMeRoofs) provides a multidisciplinary research on the roofing systems (external roof; internal wooden supporting structure; ceilings and vaults) of churches built between the 5th and 15th centuries, with the goal of creating a digital geodatabase for the architectural-historical study, the history of restorations, the typological-structural classification, the cultural contextualization and the state of conservation of the roofs. This preliminary stage of the project will focus on a specific territory that has preserved several cases of original or, at least, largely intact medieval roofing systems, despite restorations or modifications: the hinterland of the Veneto region (North Italy). This area is unique in Italy for its peculiar position, because it has received diversified cultural influences through the centuries (from East to West up to Northern Europe), which favoured the creation of different types of structures. 12 major monuments will be analysed: in this way, it will be possible to have an exhaustive sampling of all types of roofing systems built between the Early Middle Ages and the Gothic era. CaMeRoofs has the ambition to be a pilot project in Italy: based on solid European research experiences in this field, the project aims at creating an advanced and generalized system for the study and cataloguing of medieval roofs that can be continuously implemented and which will benefit the documentation, conservation and management of medieval architectural heritage. In the long term, thanks to the collaboration of other researchers, it will be possible to use this geodatabase on a much larger scale to highlight diversity and aspects that unite, across space and time, geographically distant churches with the goal of creating a European corpus of medieval roofs.

Mots clés : barrel vaults builders construction materials and techniques cross vaults dendrochronology domes geodatabase medieval roofing systems wooden ceilings wooden trusses 3d laserscanner

Participants :
- Université de Florence (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Chypre (Chypre) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 148488.0 €
Projet MULTIPLE (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Digital devices and portable media platforms have become integral parts of people's lives, causing an increase in online activities and an inclination for simultaneous consumption of different media (known as media multitasking, a.k.a MMT). Extant research suggested that MMT causes cognitive strain and emotions and influences an individual’s information processing abilities, likely influencing one’s online social behavior (OSB) (pro and antisocial). Project MULTIPLE examines how multiple dimensions (task hierarchy, emotional content of the task, and time pressure) of MMT activities may influence emerging adults' engagement in OSB. It aims to determine how changes in task hierarchy and the emotional content of the tasks affect individuals’ engagement in OSB. Whether the inclusion of time pressure in the interaction of task hierarchy and the emotional content influences individuals’ engagement in OSB. Other goals are to identify the underlying mechanisms (i.e., mediators, e.g., frustration, cognitive load) and moderators (e.g., tendency to express online, impulsivity) to understand the said relationship. The methodology integrates eye movement tracking, controlled computer-based laboratory experiments, and questionnaires. The IRTIS Dept. at the MU leads in the media and cyber-related studies and will help the researcher with the team’s state-of-the-art infrastructure. The project will create a cross-discipline theoretical framework (information and communication, cognition and media) and help generate guidelines for improving the work environment in organizations where MMT is prevalent.

Mots clés : media multitasking, online prosocial behavior, online antisocial behavior, experiment

Participants :
- Université Masaryk (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166278.72 €
Projet ROMSUR (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : SIGNED

Increasing urban traffic and environmental challenges have driven the investigation, development, and diversification of sustainable transportation alternatives globally. The resilience of these alternatives has also been considered equally important in recent research in order to ensure a more safe, accessible, and equitable transportation system during severe disruptions. However, there is a lack of comprehensive evaluation system through which urban and transportation planners can assess and plan for transport resilience in their own geographical contexts. In this regard, this research proposes a model to evaluate an overall resilience of shared micromobillity systems through their commonly available usage patterns in light of current challenges and future opportunities. Specifically, it takes major shared micromobillity programs (e.g., station-based bike-sharing (SBBS), free-floating bike-sharing (FFBS), free-floating e-bike sharing (FFEBS), and free-floating e-scooter sharing (FFESS)) operating in Europe as examples to empirically analyze the mobility patterns of their users across three timescales: before, during, and after the pandemic. As a methodology, this study will utilize a combination of quantitative and qualitative techniques. The expected outcomes will help in improving governance and an appropriate appraisal of sustainable urban transport alternatives, which are still in its infancy. The resilience assessment tool will further help develop long-term systems for measuring and executing mobility plans on both sides of the mobility equation: supply and demand.

Mots clés : shared micromobility transport resilience mobility as a service urban sustainable active mobility covid 19 europe

Participants :
- Université Masaryk (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166278.72 €
Projet SingletSQL (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The sensitivity of the next-generation gravitational-wave detectors (GWD) are critically limited by the quantum fluctuations of light. The major sources of such noises are shot noise and optomechanical back action noise (BAN). The improvement of sensitivity can be achieved by back-action evading (BAE) measurements, which allows overcoming the standard quantum limit. By trading off between shot and BAN, recently a promising scheme has been proposed which involves another auxiliary system, consisting of an atomic spin ensemble with negative effective mass that can suppress both the noises. The measurement is performed by two entangled beams of light probing the GWD and the spin ensemble. However, the approach exhibits three major implementational issues to focus on, which I have discovered by recent calculations. Firstly, I study how the sensitivity of the GWD is dependent and what the constraints introduced by the entanglement measures between subsystems. Secondly, I come with a novel approach for the BAE by using a nuclear singlet state of carbon in diamond which works at very low NMR frequencies and bandwidth aiming to avoid the discrepancies of the match between the frequencies and linewidths of the spin and the mechanical oscillators. In this aspect, I propose using a novel type readout of electron spin of NV centers, used as a non-perturbing ancilla of the nuclear spin-singlet. Finally, based on the parameters obtained from ongoing E-Test project, where a low thermal noise mechanical oscillator is being built up, I will theoretically investigate if the nuclear singlet state can match the frequency and bandwidth of rational parameters of the oscillator and whether it can be implemented for the BAE measurement. I will study the role played by the input squeezing parameters, and how to engineer the frequency range of noise suppression of the output. The proposal entitles advanced hands-on training on experimental setups and profounding my background in GWD.

Mots clés : gravitational waves, optomechanical back action, standard quantum limits, theory of quantum entanglement, nmr, nv center in diamond

Participants :
- Université de Maastricht (Pays-Bas) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut de micro-électronique et composants (Belgique) — Coordinator, beneficiary, Recherche, subvention : 175920.0 €
Projet RBNAGE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

The ultimate goal of this proposal is to decipher the role of the RNA biological noise (RBN) in the ageing brain. RBN represents a rare but real pool of RNA molecules generated as a result of transcriptional instability. However, as the RBN can only be extracted by full-length single-molecule transcript sequencing, whether RBN is associated with decline processes such as aging and neurodegeneration, remains to be elucidated. To evaluate this association, I will use readily-available data, including long-reads, single cell and spatial transcriptomics of aging mice brains. First, I will develop a methodology to distinguish technical noise from RBN in long-reads transcriptomics. Second, I will characterize the RBN to decipher its contribution to aging. Third, I will study the cell-type-specific and brain-region-specific RBN. To carry out this project, I will work with Dr. Conesa, expert in long-reads transcriptomics, method development and multi-omics. This timely work will benefit from collaboration with world leaders in single-molecule technologies participating in MSCA-DN 2021 “LongTREC” to study transcriptome biology under the coordination of Dr. Conesa. Successful completion of this project will contribute insights and software to understand the RBN across the single-molecule transcriptome, not only in the context of aging and neurobiology but also for researchers to use in other biological contexts. This project could also set important first steps towards better health, healthy aging, and a decrease in avoidable neurodegeneration.

Mots clés : aging, neurobiology, long reads transcriptomics, modelling, biostatistics, bioinformatics

Participants :
- Université Cornell (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 165312.96 €
Projet PROTECT (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : TERMINATED

Accurate assessments of species’ contemporaneous extinction risk (CER) are vital to quantifying the current biodiversity crisis and prioritising conservation efforts. However, the most comprehensive global dataset of CER - the IUCN Red List of Threatened Species - is taxonomically biased due to the lengthy assessment process, leaving understudied taxa, such as those in freshwaters, under no formal PROTECTion. Prediction-based models based on novel machine learning methods enable large-scale automated assessments of CER, reducing data deficits rapidly. The main goal of this project is to identify predictors of CER in freshwater habitats, focusing on the largest family of freshwater gastropods, the Hydrobiidae. First, we will use a deep-learning approach to automatically predict the Red List status of hundreds of hydrobiid species from multiple regions and ecosystems that have not been evaluated yet, basing the predictions on ecological and macroevolutionary data. Second, high-throughput sequencing methods will be conducted for the first time in this taxon to compare microevolutionary diversity with population trends derived from long-term field surveys. Last, by establishing a multifactorial prediction-based method, the project will identify which features (ecological, macro-, microevolutionary or all) are meaningful to inferring CER in freshwater organisms. The implications of this proposal are threefold and relevant to scientific, technological and societal concerns. Our findings may provide a basis for comparing predictors of CER across taxa. They will also open up a more integrative framework for conservation actions, moving beyond species-by-species categorisation. Focussing on the "Natural Resources, Agriculture & Environment" area from HORIZON 2021-2027, this project addresses knowledge gaps in species threats and safeguards freshwater resources, illustrating this with understudied taxa.

Mots clés : iucn red list, macroevolution, microevolution, ecology, iucnn, high throughput sequencing, museum collections, hydrobiidae

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
Projet AGRAS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Animal husbandry has been a core productive area of the European economy since the introduction of domestic animals during the Neolithic. In today's geopolitical scenario, past husbandry regimes can provide essential insights into improving the resilience of animal production, adapting to local resource availability while maximising yields. The research context of this project is medieval Sicily. Located in the centre of the Mediterranean, Sicily has always been a melting pot of different cultures; the clear affirmation of Byzantine, Arab, and Norman/Swabian rules during the Middle Ages entailed the development of distinct socio-cultural and economic models, each influenced by and adapted from previous practices. This makes Sicily a primary case-study for the understanding of the integration of different cultures and the impact of different politico-economic systems. Between the 7th and the 13th c. AD, the Mediterranean Basin witnessed an important transformation in landscape use and its management defined in the 1970s as ‘the Arab agricultural Revolution’. This concept has been revised and nuanced since, and it was probably a more gradual process than initially thought. In contrast to other materials, animal bones and teeth have been overlooked, despite they provide direct evidence of dietary habits, landscape management strategies, and economic dynamics of the past. Preliminary research suggests that the Arabs managed to produce bigger animals (and thus higher meat yields) across the Mediterranean, but how? For the first time, AGRAS will develop a multidisciplinary research combining traditional archaeozoology, collagen fingerprinting (ZooMS), isotopes (oxygen, strontium, carbon and nitrogen), dental meso and microwear to understand the reasons enabling Arabs to produce higher meat yields in a context of demographic increase and competition for resources on a European scale.

Mots clés : zooarchaeology, sheep husbandry, zooms, isotopes, dental mesowear, 3d dental microwear, middle ages, arab period, sicily, mediterranean

Participants :
- Université autonome de Barcelone (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €