Projet UPLIFT (Horizon Europe, appel à projets 2023)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

Radiotherapy (RT) is a mainstay of modern cancer treatment. Conventionally, RT is delivered to the patient lying on a treatment couch, while a beam steering device (gantry) aims the radiation from any angle around the target. Positioning the patients in upright body posture (upRT) instead enables to orient the patient arbitrarily toward a fixed beam. This enables smaller facility footprint and reduced treatment cost, placing upRT in the core of the UN sustainable development goals, and opening global access to advanced treatment options: 80% of cancer patients live in countries which host only 5% of the world’s RT resources. Moreover, upRT improves patient comfort and is associated with anatomical and physiological advantages, such as reduced breathing motion. It therefore comes as no surprise that, with new upright patient positioning & imaging solutions entering the market, upRT is enjoying a surge in interest. Yet, key scientific questions remain, international guidelines for upRT are lacking, and existing RT workflows are geared to lying patients. As the first clinics adopt new upRT technologies, there is a global need for trained professionals in industry, clinics and academia, to reach the promised benefits for patient care. UPLIFT builds this next generation of experts by addressing key research questions related to: treatment planning, clinical workflow and equipment design. Leveraging latest upRT technology available through our world-class consortium, UPLIFT propels Europe to the forefront of the upRT paradigm shift. UPLIFT focuses on: Learning (through its academic and clinical centres of excellence); Innovation (through its leading industrial partners); Fellowship & Training (through an outstanding cross-sector programme of workshops, secondments & mentoring). Input from patient advocacy groups and an internationally renowned advisory board will maximise its impact. UPLIFT will revolutionize modern RT, making it more human, accessible and sustainable.

Mots clés : upright body positioning

Participants :
- National Center for Oncological Hadrontherapy (Italie) — Partner, beneficiary, Recherche, subvention : 518875.2 €
- Centre de lutte contre le cancer Léon-Bérard (France) — Partner, beneficiary, Recherche, subvention : 565387.2 €
- Université de Sheffield Hallam (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Cosylab (Slovénie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 242179.2 €
- Institut Paul Scherrer (Suisse) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Gênes (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Leo cancer care ltd (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- GSI Helmholtz Centre for Heavy Ion Research (Allemagne) — Coordinator, beneficiary, Autres, subvention : 521078.4 €
- KTH Institut royal de technologie (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- TheraPanacea (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 282693.6 €
- Columbus Superconductors (Italy) (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 259437.6 €
- Université technique de Prague (Rép. Tchèque) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 237038.4 €
- Université technologique de Dresde (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de technologie de Darmstadt (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Loughborough (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Heidelberg (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Ljubljana (Slovénie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Jagellonne (Pologne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 226512.0 €
- Université Paris-Saclay (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Helmholtz-Gemeinschaft (Allemagne) — Partner, beneficiary, Recherche, subvention : 260539.2 €
- European Society for Therapeutic Radiology and Oncology (Belgique) — Partner, associated partner, Autres, subvention : 0.0 €
- Helmholtz-Zentrum Dresden-Rossendorf (Allemagne) — Partner, beneficiary, Recherche, subvention : 521078.4 €
- Raysearch laboratories ab (publ) (Suède) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 293709.6 €