Projet 3D NEONET (Horizon 2020, appel à projets 2016)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : CLOSED

Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascular permeability) play also pivotal roles in cancer, being therapeutic targets to treat both kind of diseases. The overall goal of 3D-NEONET is the improvement of available treatments for cancer and ocular disease by enhancing drug discovery-development and delivery to targeted tissues, through advanced international co-operation between academic and non-academic partners. The interdisciplinary expertise provided by 18 partners in 7 countries encompasses among others: drug screens, ADME, toxicology, preclinical models, nanotechnology, biomaterials and clinical trials. After the success with ongoing FP7-IAPP project 3D-NET (Drug Discovery and Development of Novel Eye Therapeutics; (www.ucd.ie/3dnet), we are assembling 3D-NEONET, this enlarged European interdisciplinary consortium that will join forces and exchange skills to enhance current therapies in oncology and ophthalmology. The 3 global objectives of 3D-NEONET are: 1- Enhance the discovery and development of novel drugs, targets and biomarkers for ophthalmology and oncology. 2- Improve the Delivery of Therapeutics for Oncology and Ophthalmology 3- Enhancement of Research, Commercial and Clinical Trial Project Management Practices in these fields. Through participation in the program, 3D-NEONET is the vehicle for driving synergies between academic and non-academic participants leading to increased scientific and technological excellence as well as tangible innovative outputs that will strengthen the competitiveness of both the researchers and industries of the network even beyond the lifetime of the network.

Mots clés : zebrafish, phenotype based drug discovery, drug delivery, natural products, drug metabolism, cancer xenografts, colorectal, oesophageal cancer, uveal melanoma, diabetic retinopathy, amd clinical trials

Participants :
- Experimentelle pharmakologie und onkologie berlin-buch gmbh (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Ocupharm diagnostics sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 330120.0 €
- Cresset biomolecular discovery limited (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Karlsruhe Institute of Technology (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 4950.0 €
- National University of Ireland (Irlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 31500.0 €
- Xenopat sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 14715.0 €
- International Iberian Nanotechnology Laboratory (Portugal) — Partner, beneficiary, Recherche, subvention : 56250.0 €
- Universidad Complutense de Madrid (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 70200.0 €
- Icon clinical research limited (Irlande) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- University of Valladolid (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 13500.0 €
- Trinity College Dublin (Irlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 18000.0 €
- South East Technological University (Irlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 9000.0 €
- Blafar limited (Irlande) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 22500.0 €
- Linköping University (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 65565.0 €
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195975.0 €
- Ecm ingenieria ambiental sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 50850.0 €
- ZeClinics (Spain) (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 9000.0 €
- Hgbeyond materials sicence sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 13500.0 €
- Vornia (Ireland) (Irlande) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Bioreperia ab (Suède) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Eyecro llc (Etats-Unis) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Queen's University Belfast (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 39375.0 €