Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet PHOMOTRIPP (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Harnessing indoor lighting available in buildings has the potential to power the next generation of Internet of Things, creating a more environmentally and economically sustainable ecosystem to accelerate future innovation. Indoor photovoltaics enable this by utilising artificial light sources such as white light-emitting diode and fluorescent lamps to negate the limitations imposed by battery-powered systems. Among the emerging photovoltaic technologies, indoor perovskite solar cells display immense promise and require further study to reach their true potential. The electron transport layer, an integral part of the perovskite solar cell architecture, is of particular interest as its optimisation can lead to overall enhancement of device performance in indoor conditions. Popular metal oxide-based electron transport layers, that offer solution processability, tunable electronic properties, high carrier mobility, and favourable energy level match with the perovskite, continue to suffer from high temperature processing and interfacial defects. Lowering the processing temperature to increase compatibility with flexible devices, diversifying the metal oxide family to develop a wider choice of materials, and formation of metal oxide composites to augment charge transfer and stability, are some measures that can overcome the challenges of the present transport layers and further enhance their properties. This study attempts to achieve this by innovatively combining low temperature photo-annealing and graphene incorporation to produce high quality films of conventional and novel metal oxides, that can be employed in indoor perovskite solar cells to improve overall device efficiency and stability. This proposal is a focussed but significant attempt to fill the gap arising from a lack of concentrated study on electron transport materials, more specifically inorganic metal oxides in the domain of indoor perovskite solar cells.

Mots clés : electron transport materials, metal oxide, graphene composite, sol gel, photo annealing, indoor perovskite solar cell, flexible photovoltaics, energy harvesting

Participants :
- Université de Rome « Tor Vergata » (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 188590.08 €
Projet EFESO (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

EFESO, acronym of "Exploiting Flexible pErovskites Solar technOlogies" aims to bring perovskite technology on flexible substrates towards commercialization. This project aims at upscaling stable Flexible Perovskite Solar Modules (FPSMs) by optimizing their fabrication process on flexible substrates, reducing inactive areas on modules, and by working on lead (Pb) trapping intrinsically, using doping and interface engineering, and extrinsically by encapsulation strategies.  The proposed project is divided into 3 main parts: 1. Materials: assessment of the flexible substrates, additives, and interface layers to get the best and stable layer to be used for device fabrication;  2. Device: fabrication and characterization of devices, focusing on lead trapping strategies by encapsulation and interface engineering;  3. Upscaling: optimization of the design and laser processes of P1-P2-P3 for indoor and outdoor applications (standard procedures to create a series connection of cells, to reduce losses encountered for large-area devices).  The principal objective of this action will be the fabrication of Flexible Perovskite Solar Cells with performances of 23% and 35% on small area devices at 1 Sun and 1000lx intensity respectively, FPSMs with power conversion efficiency (PCE) of 21% and 18% on an area greater than 10cm2 and 200cm2 respectively. All devices fabricated will pass the ISOS D-L-T-1 tests and they will show a reduction of lead leakage by 4-5 orders of magnitude A final product demonstrator will be fabricated showing the applicability of these devices into the market.  The action will bring new materials, additives, sealants, polymers, solvent concentrations used to limit lead leakage, and build a stable and highly efficient device on a flexible substrate, from cell to module size. For these reasons, this action will grab the attention of the scientific community that will recognize this work as a potential path for prompt commercialization.

Mots clés : perovskites, flexible substrates, perovskite solar technologies, solar technologies, perovskite solar modules, commercialization, iot, semiconductors, interface engineering, solution processes

Participants :
- Université de Caroline du Nord à Chapel Hill (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Saule spolka akcyjna (Pologne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université de Rome « Tor Vergata » (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 288112.44 €
Projet INT-PVK-PRINT (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Hybrid perovskite photovoltaics (PV) are considered one of the most promising emerging PV technologies that have the potential to becoming a vital part of future’s renewable energy production needed for combating climate change. However, the community still struggles with the scaling and reproducibility when printing perovskite thin-film absorber layers from solution due to the complex perovskite formation process that is susceptible to a variety of environment and process parameters. This project proposes a novel interface between perovskite solution printing and algorithmic optimization and control theory by equipping a roll-to-roll perovskite printing line with in situ characterization, computational data processing and automatically adjustable process parameters. The characterization is given by point-probe reflection/absorption as well as luminescence imaging measurements. Feedback for control is calculated in real-time using simple control algorithms, at first, and progressing in complexity toward the employment of deep reinforcement learning (DRL), later on. The images are analyzed offline using convolutional neural networks for optimizing absorption/reflection set points for the above-described feedback control. The proposal has two main goals: 1) Boosting the optimization of perovskite solution printing by effectively balancing exploration and exploitation of the large parameter space 2) demonstrating enhanced process control of certain system states to achieve higher process reproducibility and resilience in perovskite printing. These goals are complementary in a sense that control is exceeded on rapidly accessible parameters while optimization is performed with slowly accessible parameters. In conclusion, this proposal presents a fundamental and concise new methodology of addressing reproducibility and scalability in perovskite solution printing that could be used for printing of functional thin-film, as well, highlighting its generality.

Mots clés : scalable roll to roll coating, hybrid perovskite photovoltaics, in situ characterization, luminescence imaging, deep machine learning, deep reinforcement learning, convolutional neural networks

Participants :
- Université technique de Munich (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Rome « Tor Vergata » (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 188590.08 €
Projet GDSNL (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

GaN substrate materials have been increasing the demands of applications such as wireless communications, super-high computing, and power-management IC. The growing demands create substantial challenges for both the development of new semiconductor materials and their thermal power management in very large-scale integrated circuits. The highly localized Joule self-heating at the drain edge of the gate degrades the electrical performance and reliability of integrated circuits by introducing the device's channel thermally activated degradation mechanisms. To improve the radiation effect, the localized device's drain and channel regions heat generated in the active region of Si-substrate GaN high electron mobility transistors (HEMTs) device must be efficiently restrained. Third-generation semiconductor SiC and diamond, their appearance has improved high power reliability and performance, however, this direct growth requires an AlN or a SiN nucleation layer and suffers from the cost-effective large wafer. Besides, to date, GaN devices are mainly fabricated on sapphire, Si/SiC substrates having thermal conductivities of about 0.5, 1.5, and 4.0 W/cm·K, but the heat generated in GaN-on-diamond structure devices can be easily dissipated due to the excellent thermal conductivity characteristics of a diamond (thermal conductivity: ~22 W/cm·K). In order to conquer the growth of AlN or SiN GaN heterostructures on high poly- or micro-crystalline diamond and realize high-performance heat dissipation, a novel diamond growth on Si process using liquid gallium and titanium at low atmospheric pressure and a SAB Si-based nanolayer integration GaN-on-Si technology have been proposed. In this proposal, commercial GaN-on-Si and fabricated Diamond-on-Si were bonded with an extraordinarily low TBR and surface defects, this work opens up a new way for the fabrication of Diamond-based high-power wafers.

Mots clés : gan, diamond, hfcvd, sab, hemts

Participants :
- Université d'Aveiro (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172618.56 €
- Institute for Systems Engineering and Computers (Portugal) — Partner, associated partner, Recherche, subvention : 0.0 €
Projet MAACS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The main aim of the MAACS project is to explore if specific changes in epitranscriptomic landscape of peripheral blood mononuclear cells (PBMCs), particularly N6-methyladenosine (m6A) RNA modification, could be used as a biomarker for acute coronary syndrome (ACS) differential diagnosis and prediction of future adverse outcomes. This project will be the first to (1) identify ACS-specific m6A biosignatures in PBMCs using direct RNA Nanopore sequencing, (2) quantify total m6A RNA modifications in PBMCs of ACS and stable angina patients using LC/MS, (3) assess the clinical utility of total m6A RNA modification in PBMCs, and (4) perform an in vitro functional analysis of ACS-specific m6A modifications. The realization of set objectives will reveal novel mechanisms implicated in the aggravation of ACS that could lead to the development of novel tools for personalized prevention, diagnosis, and treatment. In order to utilize the power of the integrative and multidisciplinary approach, this project will establish collaboration between Dr. Miron Sopic (MSCA PF applicant) and top-tier institutions: CardioVascular Research Unit-Luxembourg Institute of Health (beneficiary) led by Dr. Yvan Devaux (The project’s supervisor), McGill University in Quebec (associated partner for secondment), and University of Luxembourg (associated partner). Working in the international environment with eminent experts and a productive team of researchers and using state-of-the-art infrastructure and techniques will secure the applicant to become an internationally recognized expert in the epitranscriptomic field and an independent researcher with strong credibility competent to establish and lead his research group. MAACS contributes to sustainable development by complying with several objectives: good health and well-being, quality education, gender equality in research, reduced inequalities, and partnership for the goals.

Mots clés : epitranscriptomics rna modifications

Participants :
- Université du Luxembourg (Luxembourg) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université McGill (Canada) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Luxembourg Institute of Health (Luxembourg) — Coordinator, beneficiary, Recherche, subvention : 191760.0 €
Projet MATER (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

One over three women with breast cancer will develop mental health issues, adding the burden of a deterioration of their quality of life to the management of cancer itself.  The objective of the MATER project is to improve the detection and monitoring of mental health in women with breast cancer by leveraging symptom networks and vocal biomarkers. The project addresses three research questions. We first hypothesize that the use of symptom networks will allow a better understanding of the links between depressive symptoms, fatigue and a decreased quality of life, and identify the most important symptoms in the deterioration of the mental health of these women. We also assume that automatically estimating these symptoms using voice descriptors extracted from real-life recordings and machine learning pipelines will make it easier to monitor them in the patients' homes. Finally, we hypothesize that the use of a Bayesian network algorithm combining the symptom network and the voice-based symptom estimations will allow a more accurate joint estimation of these symptoms - and thus improve the identification and monitoring of mental health-related symptoms in women with breast cancer.  The interdisciplinary MATER project is based on Colive Voice, a unique dataset of clinical and voice data and leverages both the complementary host's and supervisor's extensive experience in digital and personalized health and the applicant's knowledge of vocal biomarker design and machine learning, mental disorder semiology, and Bayesian networks. This project will allow the applicant to improve his skills in voice signal processing, precision health (in particular in oncology), but also in scientific project management and in research valorization, creating an international network and elevating his profile to such levels as to accelerate his access to high-level academic positions.

Mots clés : symptom networks vocal biomarkers

Participants :
- Luxembourg Institute of Health (Luxembourg) — Coordinator, beneficiary, Recherche, subvention : 175920.0 €
Projet INCEPTOR (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

One of the major mechanisms by which solid tumors escape anti-tumor immunity is the downregulation of major histocompatibility complex class I (MHC-I), which causes a failure in the recognition of tumor cells by the cytotoxicity T-cells. The project proposed by Dr. Teresa Ramos contains basic and translational aspects. The basic aspect relies on investigating the mechanisms of action of the ACB1801 molecule (harmine), reported by the host team to restore the MHC-I in tumor cells, using state-of-the-art technologies. The translational aspect of the project relies on providing the preclinical proof of concept for an innovative immunotherapy combination. The combination strategy consists of using a vaccination approach with Dendritic Cells (DC), pulsed with tumor cells pre-treated with ACB1801, in combination with immune checkpoint blockades. Although DC vaccination constitutes potent anticancer immunotherapy, clinical data showed that it does not provide robust benefits to patients. the innovative strategy of the project is based on simultaneous boosting the DC-based vaccine by ACB1801 and unleashing the power of T cells to induce a robust anti-tumor immune response which constitutes an unmet clinical need. The development of the present proposal will enable Dr. Ramos to achieve a broad range of new technologies and management skills through a variety of multidisciplinary training programs. This will represent a key step toward her final objective to become an independent and competitive scientist.

Mots clés : carboline harmine, acb1801, mhc i, dendritic vaccine, immune checkpoint blockade, pd 1, melanoma, colon carcinoma

Participants :
- Luxembourg Institute of Health (Luxembourg) — Coordinator, beneficiary, Recherche, subvention : 191760.0 €
Projet RADICAL (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Life history theory (LHT) provides fundamental means to understanding adaptive evolution across the animal kingdom, including in our own lineage. Although observational studies have found plenty of support for the predictions of LHT in human populations, connecting traits such as birthweight and adult body size to age of menarche and menopause as well as disease risk, the fundamental biological mechanisms linking many of these traits are poorly understood. Here I propose, for the first time, to bring together matching genotype and phenotype data from two large national biobanks and state of the art statistical tools and genetic databases to formally investigate the extent to which the observational links between reproductive and anthropometric traits can be explained by pleiotropy and/or shared genetic pathways as well as the extent to which these pathways have been subject to natural selection over the past 10,000 years. The proposed interdisciplinary project, carried out at the Institute of Genomics, at University of Tartu (IGUT) will enable me to learn advanced techniques in association mapping as well as management of a project involving biobank and other clinical data under the supervision of experienced researchers at statistical and medical genomics. As such, the project provides an outstanding launchpad for the next stage in my research career at the intersection of evolutionary and medical genomics as an independent group leader.

Mots clés : life history theory evolutionary trade offs reproductive and anthropometric traits regulatory networks ancient dna

Participants :
- Université de Tartu (Estonie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 167741.76 €
Projet SPRUT (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

This project is devoted to synthesis of non-isocyanate polyurethanes (NIPU) from bio-based sources and their post-modification towards industrial application. The use of bio-based monomers for NIPU synthesis allows to overcome the dependence on fossil resources and to reduce the CO2 emissions. However there are several possible drawbacks for industry such as high prices for bio-based monomers and demand for arable land to ensure large scale production. NIPU were introduced in 1990s as the alternative to conventional polyurethanes because they allow to avoid usage of toxic isocyanates. However, they were not industrialised due to their insufficient molecular weights limited by reaction ability of monomers and increased hydrophilicity that facilitates hydrolysis during processing. The SPRUT project will simultaneously deal with several NIPU related issues. At first, the effective catalyst based on Al heteroscorpionate complexes for converting bio-based bisepoxides to 5-membered cyclic bicarbonates via CO2 addition will be developed. The obtained bicarbonate bio-compounds will be used as feedstock for production of NIPU applying various approaches to increase their MW above 20000 Da: synthesis in bulk, copolymerization of two different bicarbonates and the use of ionic liquids. In the 2nd stage of the project, the unique method for post-synthetic modification of NIPU that was never used for these polymers will be introduced to increase their mechanical properties and processability. The basic “click” reaction of bio-based aldehydes (heptaldehyde and benzaldehyde) with adjacent hydroxyl groups in the NIPU backbone enables the reduction of intermolecular hydrogen bonding leading to better processability. The resulting aldehyde modified NIPUs containing non-polar side chains are supposed to be much more hydrophobic and possess increased physico-mechanical properties compared to previously developed NIPU and even some conventional PUs.

Mots clés : polyurethanes nipu bio based polymer modification vitrimers

Participants :
- Luxembourg Institute of science and technology (Luxembourg) — Coordinator, beneficiary, Recherche, subvention : 191760.0 €
Projet TD-PICO-MF (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The recent development of broadband coherent extreme ultraviolet sources makes it possible to measure dynamics with attosecond resolution (1 attosecond = 10-18 s). This time scale is associated with the electron dynamics and more particularly to the electronic correlation in various systems, from atoms and molecules to solids. Generating and controlling processes on this time scale then gives the opportunity to develop new promising applications in chemistry and biology that can have high impact in society. TD-PICO-MF aims at studying electronic correlation through the measurement of the photoemission delay of core-orbital electrons in a laser-controlled molecular system. For this purpose, TD-PICO-MF brings together advanced technologies from the attosecond interferometry field and laser-induced alignment field, in order to resolve both spatially and temporally the photoemission process. In particular, the research project proposes to study, as a prototype, the photoemission from the 4d core-orbitals of the iodine atom in iodine monochloride (ICl) molecules in gas phase. The measurements will be realized during different laser controlled configurations of the molecular system e.g., during its alignment, orientation and dissociation. The expected impact is to gain a global picture of the influence of the molecular cationic potential during a chemical reaction and to evidence the role of electronic correlation through the measurement of 3D-scattering phase maps in the molecular frame. TD-PICO-MF will utilize existing, and forge new, international collaborations between experiment, theory and academia in order to tackle this complex problematic. The results of our work will be made globally available and presented to the general public. The post doctoral fellow will bring to the host his expertise on laser control of molecular systems and will be trained to the attosecond science and technologies, enlarging his scientific experience and employability.

Mots clés : attosecond ultrafast strong field molecular physics high harmonic generation rabbit laser induced alignment time resolved photoemission velocity map imaging core orbital ionization

Participants :
- Commissariat à l’énergie atomique et aux énergies alternatives (France) — Coordinator, beneficiary, Recherche, subvention : 195914.88 €