Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet ANCIENT_TEETH (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The transition to an agriculture lifestyle is one of the most important events in human evolution, resulting in significant biological, cultural and health changes. This shift started in the Great Hungarian Plain (GHP) around 6,000 cal BC, followed by several cultural and technological transitions during the next several millennia. The objective of the present project is to characterize, for the first time, the changes in dental traits of past European populations and the factors influencing these transitions, integrating data from several multidisiciplinary, state-of-the-art approaches. These will include: 1) Training in and obtaining high-resolution μCT data of upper and lower molars from a unique unstudied Hungarian time-series; 2) The characterisation of internal and external dental morphology trait changes through geometric morphometric and occlusal complexity methods; 3) The use of stable isotope analyses to analyse these populations’ diet; 4) The use of modern ancient DNA techniques (Next Generation Sequencing, NGS) for sexing individuals and subsequent study of sex differences in morphology and dietary regimes through time. This project will not only expand the knowledge of the consequences of adopting agriculture, but will also explain the origins of dental health problems in contemporary populations. More importantly, it will constitute the starting point for developing a long term project characterising the dental trait changes caused by dietary shifts and will provide insight into how these transitions took place throughout the continent. The project will enable the successful collaboration between the School of Archaeology and School of Medicine in University College Dublin, under the supervision of Drs. Ron Pinhasi and Robin Feeney, worldwide experts on the agricultural transition and μCT data processing, respectively. This project will broaden the multidisciplinarity of the prospective fellow and will propel her research career in the EU and worldwide

Mots clés : cultural transitions, neolithic, iron age, great hungarian plain, diet, stable isotopes, wear, tooth morphology, geometric morphometrics, microtopography, past pospulations, ancient dna, molecular sex

Participants :
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175866.0 €
Projet PreclinSR (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The translational paradigm of testing stroke treatments in animal models before proceeding to clinical trial has resulted in little success. A number of scientific practices likely contribute to this translational failure: Low study quality and bias in animal studies can cause overly or falsely positive results. Failure to publish outcomes contributes to an inaccurate body of knowledge and the wasteful duplication of experiments. Limited analysis of previous literature leads to weakly justified studies that may not investigate the most promising treatments. I aim to address these issues by developing new approaches to systematic review. Systematic review and meta-analysis are transparent, reproducible methods to objectively synthesise and interpret scientific evidence. They are routinely used in clinical research to support evidence-based healthcare decisions but remain underdeveloped and underutilised in preclinical research. Current systematic review methods provide a summary effect of treatments but do not adjust for the quality of evidence from different studies or the range of conditions where an intervention is effective. Additionally, while they are used to summarise data from different studies, they cannot present the comparative effectiveness of different treatments. I will develop sophisticated statistical techniques to address these drawbacks and analyse published literature describing animal models of stroke. I will be one of the first to adapt the powerful new method, network meta-analysis, to assess preclinical data. My results will inform drug selection for preclinical multicentre stroke trials and identify aspects of experimental design that contribute to biased research outcomes. Gaps in current knowledge will be identified, focussing animal experiments and reducing unjustified animal use and the duplication of studies into low potential areas. My new approach can be used for prioritising research in a broad range of biomedical fields.

Mots clés : systematic review, ischaemic stroke, animal models

Participants :
- University of Edinburgh (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet CO-HTL4BIO-OIL (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

The transport sector is the highest consumer of fossil fuels accounting for 96% of the global energy, which correspond to 65% of the global crude oil consumption. The escalating consumption of fossil fuel causes deleterious environmental pollution by releasing > 7 billion tons of CO2 in the atmosphere. The awareness to transition from conventional fossil fuel to eco-friendly options has resulted in several decarbonization strategies with Europe’s priority to develop new alternative and carbon-neutral energy sources based on a cost-effective biomass-based thermochemical conversion. Hence, the objective of CO-HTL4BIO-OIL is to develop commercially viable catalytic co-hydrothermal liquefaction (CO-HTL) that converts 2G wet solid food by-products such as rye straw, shellfish, and beef tallow into a sustainable transport fuel with potential 100% atom efficiency, low production costs, and zero CO2 emissions. The specific experiments include: (1) identify proper pretreatment prior to CO-HTL for efficient removal of undesirable heteroatoms (2) validate baseline Lab-scale CO-HTL by determining integrated models of HTL parameters and proportions of binary/ternary mixtures; (3) establish efficient catalytic upgrading to bring the HTL intermediate bio-crude oil to drop-in transport fuel; (4) carry out bench-scale HTL for techno-economic assessment. It is anticipated that an in-depth study on the HTL parameters, optimization of the CO-HTL process, and techno-economic assessment will provide an outlook scenario of the industrial-scale process for high biofuels production capacity. Therefore, CO-HTL4BIO-OIL will diversify my scientific competences in renewable energy and equip me with new transferable skills. Thus, combining my skills in carbon-based biomaterials with the host’s expertise in advanced biofuels, a mutual benefit will be realized. The project will positively impact Europe’s knowledge-based economy and society towards sustainable and green transportation.

Mots clés : wastes management, food byproducts valorization, renewable energy, bioenergy, biomass conversion, transport biofuel, pollution, environmental technology, chemical engineering, catalytic upgrading

Participants :
- Aalborg University (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 207312.0 €
Projet PNECtumor (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The ultimate goal of my research is to elucidate pathways involved in lung neuroendocrine tumor (LNET) formation. LNETs arise from a rare lung cell population, called pulmonary neuroendocrine cells (PNECs) and account for 20- to 25% of all lung cancers. Despite their involvement in LNETs and a number of other respiratory diseases, relatively little is known about the normal function of PNECs or their contribution to cancer development and progression. Utilizing a novel organoid based strategy for in vitro isolation and analysis of PNECs, I will develop a model of LNE tumorigenesis with a focus on two LNET subtypes, small cell lung cancer (SCLC) and atypical carcinoids (AC). Altogether, the experiments outlined in this proposal are focused on the functional characterization of PNECs and the elucidation of the pathways involved in the transformation of this cell type during LNET formation.

Mots clés : lung neuroendocrine tumors, lung cancer, pulmonary neuroendocrine cells, organoids, small cell lung cancer

Participants :
- Royal Netherlands Academy of Arts and Sciences (Pays-Bas) — Coordinator, beneficiary, Recherche, subvention : 177598.8 €
Projet POLYFIL (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The ultimate goal of the proposed project Polychromatic low-threshold fibre laser (POLYFIL), is to train a talented researcher with high potential through a research focused on the development of a new type of fibre lasers based on innovative technique of the controlled light localisation. The success of this interdisciplinary project will lead to a novel attractive fibre laser design with multiple localisation-based characteristics including prescribed polychromatic lasing frequencies with disciplinary lasing energies, extremely low threshold and stable lasing output. The Fellow, Dr. Hongwei Yin will be trained in the emerging field of science, technology and industrial applications of new types of photonic and fibre-optic polychromatic devices at the Aston Institute of Photonic Technologies (AIPT) (host - Dr. Turitsyna) and the EU industrial secondments: sensing - FOCUS (Dr. Martín-Lopez), medical photonics - ARTPHOTONICS (Dr. V. Artjushenko) and food industry - BRANSCAN (Dr. A. Erdentug). The Fellow will transfer to the EU partners important knowledge of advanced numerical techniques and new designs of photonic devices. The POLYFIL outputs will be valuable to the EU photonics industry by offering the extremely low threshold polychromatic fibre laser that is of interest for a range of applications varying from laser science, quantum technology, and optical communication, to medical applications and optical sensing with a special focus on food industry. The technology resulted from the POLYFIL outputs will contribute to the enhancement of EU scientific excellence. An important outcome will be the formation of a strong long-term collaboration network between the Fellow’s host university in China, AIPT, FOCUS, ARTPHOTONICS and BRANSCAN, bringing together the European and Chinese research centres of excellence. Overall, POLYFIL will contribute to European leadership in advanced photonics research and technology.


Participants :
- Aston University (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet THESYS (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

The unprecedented amount of photometric, spectroscopic, and astrometric data for billion stars provided by ongoing and future surveys and instruments (Gaia, APOGEE, WEAVE, MOONS, 4MOST, LSST, ELT, JWST) are allowing and will allow the detailed exploration of the Galactic history. These data will include kinematic and chemical information for stellar populations in all Galactic structures, such as the Galactic centre, globular clusters (GCs), their streams and escapees. Therefore, it is extremely timely to build a large library of models to exploit the data using star clusters as fossil records of past satellite accretion events. This motivates my work at GEPI, where I will link the large-scale dynamical evolution of Milky Way-like disc galaxies to that of their pc-scale elementary bricks as globular and nuclear star clusters (NSCs). By means of detailed N-body simulations, I will model the merger history of the Galaxy and follow the evolution of the GC system formed in the Milky Way and accreted from satellite galaxies. I will also make significant steps in advancing the understanding of NSCs, their formation and evolution and their link to the evolution of GCs and bulge/disc stellar populations. This project will greatly benefit from the knowledge and research done in the "Equipe Physique Stellaire et Galactique” of the GEPI laboratory at the Paris Observatory. This group has leading experts in the field of Galactic dynamics and stellar populations, chemical abundances of individual GCs, and is also strongly involved in the Gaia mission, and follow-up surveys (WEAVE, MOONS). Therefore, this environment is ideally suited for me to conduct my research. At the same time, I will bring in my expertise on the dynamical evolution of dense stellar systems, along with my international collaborations. The training provided at GEPI and Paris Observatory will be crucial to strengthen my skills and my professional profile, opening significant career development opportunities.

Mots clés : milky way formation and evolution, globular clusters, nuclear star clusters, stellar populations, n body, simulations, gaia

Participants :
- Centre national de la recherche scientifique (France) — Coordinator, beneficiary, Recherche, subvention : 196707.84 €
Projet FEDCIT (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The unprecedented number of newcomers in the past year provides an immense challenge to federal state and local authorities, who have to co-ordinate the provision of policies and funds for incorporating immigrants into society. This comparative study seeks to understand the role of federal states for the incorporation of immigrants in the context of the recent influx of asylum seekers in Germany and Austria in 2015. Few studies have so far investigated the role of federal states in immigrant incorporation and no research has yet been carried out on the character of federal state immigrant incorporation policies that captures institutional structures, officials and immigrant spokespersons’ agency as well as the role of power in the design and implementation of these policies. By bringing together debates on multi-level governance as well as cities as scale the research advances our concepts of the governance of immigrant incorporation in a globalised and interconnected world. Using mixed methods, the project applies an institutional ethnography of federal state ministries responsible for immigrant incorporation that allows tracing internal processes of policy development and observing interactions between the involved institutions and actors. The yielded thick description is combined with economic data as well as interview data and policy documents. By deploying a comparative research design that consists of case studies in four federal states (Baden Württemberg and Saxony, Upper Austria and Burgenland), two of which are located in Germany and two in Austria, the project identifies the impact of different factors on federal states’ immigrant incorporation policies, namely the national level’s stance towards immigration, the regions’ economic positionality, and local actors’ active lobbying on the federal state level.


Participants :
- University of Vienna (Autriche) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166156.8 €
Projet CompSci (Horizon 2020, appel à projets 2019)
Action : Cofund Doctoral programme
Statut du projet : SIGNED

The use of computing is revolutionizing research, industry, government and society, and new skills are needed to be competitive. The COMPSCI doctoral program will train science researchers and innovators with disciplinary, interdisciplinary and transferable skills and a foundation in computational methods to become Europe’s digital leaders across disciplines and sectors. COMPSCI is a 5-year program applying for 32 PhD positions of 36 months each in two calls over the program period, a total of 1152 researcher months. COMPSCI will be based on an open, transparent and merit-based selection process open to candidates from any nationality. The program emphasizes the development of computational skills and application and integration of these skills in a research project, in addition to transferable skills training in a cross-sector secondment. Candidates will go through an initial intensive training in computational methods and will then apply these skills in a research project in their science discipline – bioscience, geoscience, chemistry, materials science, physics, astronomy or mathematics – in top international, interdisciplinary research groups. This provides the candidates with skills that improve employability and their impact in their field of research, forming a basis for an exceptional career in research or innovation. The program will be hosted by the Faculty of Mathematics and Natural Sciences at the University of Oslo, Norway. The University of Oslo is leading in research and innovation in Norway and ranked as the top three university in Scandinavia (Shanghai, 2019). The program will include 35 secondment host institutions. The computational training program will be organized by the Center for Computing in Science Education – a leading hub for the integration of computing in education programs. The overall budget of COMPSCI is €8,623,872, of which € 2,603,520 (30%) are requested by the EC and 6,020,352 (70%) are covered by UiO.

Mots clés : digital competence, computational science, computational physics, computational neurophysiology, computational chemistry, computational astrophysics, computational geoscience

Participants :
- University of Oslo (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 2603520.0 €
Projet NANOLIPID (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

The use of lipid nanoparticles as carriers of lipophilic functional compounds is emerging as a promising way to efficiently deliver food ingredients. There are evidences that bioactive compounds incorporated in lipid nanoparticles present an enhanced bio-accessibility in the gastrointestinal due to their small droplet size. However, the incorporation of active nanosized ingredients in foods remains a challenge for the food sector. Lipid nanoparticles may interact with the food matrix components causing destabilization phenomena or binding, which in turn might decrease their biological activity. Moreover, food processing operations used after the incorporation of the active lipid nanoparticles may have an impact in their properties. In this context, NANOLIPID, aims to contribute to the design, characterization and application of bioactive lipid nanoparticles towards a more rational and optimal use of food ingredients. For that purpose, the major goal of this proposal is to obtain stable lipid nanoparticles containing carotenoids (β-carotene, lycopene and lutein), incorporate them in complex food systems and assess their digestibility and bio-accessibility under in vitro simulated digestion conditions. NANOLIPID is a multidisciplinary proposal covering the formulation of lipid nanoparticles and use of state of the art techniques for nanomaterial characterization, food processing, and analysis of digestion and in vitro bio-accessibility. The fellow, who recently obtained her PhD degree in the University of Lleida (Spain), focuses on the study of the functional properties of lipid nanoparticles. Currently, she is post-doctoral researcher at the Food Science Department at University of Massachusetts (USA), one of the most active research groups in the field of delivery systems. The applicant would be one of the first researchers in Europe to study the real implications and benefits of incorporating functional lipid nanoparticles in food products.

Mots clés : lipid nanoparticles, nanoemulsions, carotenoids, foods, ingredients, food processing, food matrix, interactions, in vitro digestion, lipid digestibility, carotenoid bio accessibility

Participants :
- KU Leuven (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 160800.0 €
Projet ANAMNE (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The use of martyrdom narratives by religious institutions and believers in Eastern Europe to deal with the deaths of men and women who perished in communist purges and camps has attracted scholarly attention, but still lacks a comprehensive treatment. In particular, the mass canonisations and commemorations of so-called New Martyrs by the Orthodox churches suggest that religion has an important role to play in shaping narratives of the past and, thus, affecting collective identities. Yet, because works on post-communist non-secular memory are generally lacking, the role of East European churches in the process of coming to terms with the past remains poorly understood. The aim of ANAMNE is to provide a comparative, evidence-based study of Orthodox commemorations of New Martyrs in three national contexts, Russia, Ukraine and Estonia, with a special focus on gender, in particular on the lack of female New Martyrs. Using an interdisciplinary approach of memory studies, cultural history, anthropology and religious studies, this innovative study will provide insight into the relationship between the communist past and the collective identities of contemporary Orthodox Christians, and contribute to our understanding of the workings of martyrdom narratives globally. Expected outcomes of the study will be a change in the attitudes of the various stakeholders towards religion’s role in the process of ‘coming to terms with the past’. More broadly, the project will advance the excellence of comparative research on memory and religion in several Widening EU countries, a large majority of which have strong Orthodox representation. This MSCA fellowship in the Faculty of Religion and Theology at the Vrije Universiteit Amsterdam will allow the very Experienced Researcher to build strong leadership in her field, take the next step towards a research professorship, and strengthen her international networks and funding.

Mots clés : post communist memory, orthodox church, martyrdom, the cult of saints, iconography, the relics, hagiography

Participants :
- Vrije Universiteit Amsterdam (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 187572.48 €