Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet iCARE-2 (Horizon 2020, appel à projets 2017)
Action : Cofund Postdoctoral programme
Statut du projet : SIGNED

iCARE-2 is an ambitious programme offering 30 three-year international fellowships to foster excellence in cancer research, based on the mobility of postdoctoral researchers. iCARE-2 proposal is presented by AIRC, the Italian Association for Cancer Research, as beneficiary. AIRC, a private non-profit association, was created in 1965 by visionary Italian scientists returning to Italy after a successful work experience abroad, with the mission to find a cure for cancer through research. Nowadays AIRC is the Italian leading charity providing about 40% of all funds invested in cancer research in Italy and supporting hundreds of research projects and fellowships in any cancer-related fields. Grants and fellowships are awarded with a merit-based selection process. To train excellent and innovative cancer researchers iCARE-2 programme will: 1. let fellows choose the cancer-related topic of their research and the best supervisor and Hosting Institution, worldwide; 2. offer and promote training in transferable skills, with a special focus on research integrity, science communication, grantsmanship, project management and intellectual property rights; 3. support international networking, not only with the mobility inherent to the program but also through interactions with other fellows and with AIRC. Optimal employment and working conditions will be guaranteed to all iCARE-2 fellows to foster their personal and financial stability and to ensure excellence of their research activities.

Mots clés : cancer, research, oncology, health sciences, cancer awareness, transnational mobility, post doctoral, fellowship training, knowledge transfer, peer review, dissemination, outreach, career development

Participants :
- Italian Association for Cancer Research (Italie) — Coordinator, beneficiary, Autres, subvention : 3186000.0 €
Projet HollidayTrack (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

omologous recombination (HR) is a DNA repair pathway that plays a central role in the maintenance of genomic stability and cancer prevention. In the late stages of HR, recombination intermediates (Holliday junctions, HJs) need to be resolved to allow proper chromosome segregation. Whilst HJ processing reactions have been well characterised in vitro, there is limited knowledge of the dynamic properties of these structures within a cellular context. To explore the biological properties of HJs in vivo, I will use site-specific DNA cleavage and ChIP-sequencing techniques to reveal the distance of HJ migration from the site where HR is initiated. The ability of HJs to branch migrate spontaneously or be driven by potential HJ translocases will be determined using RAD54, BLM, WRN, RECQ1, RECQ5 and FANCM deficient cells. To enable these studies, my first challenge will be to develop a molecular tool that specifically detects HJs in vivo, that can be used to monitor the appearance and kinetics of HJs after DNA double strand break formation. The specific DNA break sites and corresponding HJ migration will be determined with respect to the dynamic chromosome domain architecture and organisation within human cells, which will provide valuable insights into the impact of local chromatin structure on HJ migration and resolution. Additionally, the newly developed HJ-specific tools may be applied to ask a wide range of questions relating to the role of HJs in telomere biology and replication fork reversal or to study patterns and distributions of HJ formation and migration in different cancer cell types.

Mots clés : homologous recombination, holliday junction, branch migration, dna helicases, chromatin topology

Participants :
- The Francis Crick Institute (Royaume-Uni) — Coordinator, beneficiary, Recherche, subvention : 212933.76 €
Projet NanoCuI (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

p-Type dye-sensitized photocathodes (p-DSSCs) are a new type of solar energy device. They promise to increase the efficiency of dye-sensitized solar cells (DSSCs) by enabling tandem cells that absorb light at both electrodes, in similar fashion to multi-junction semiconductor PV. However, no component of the p-DSSC is fully optimised, and the nickel oxide (NiO) substrates used as the p-type semiconductor appear to be a particular weak point, due to their inefficient charge transport. In this project, we will develop new copper(I) halide electrodes which transport charge much better, and will potentially form the heart of new, efficient p-DSSCs.

Mots clés : copper iodide, p type dye sensitized solar cells, sensitizer dyes, electrochemistry

Participants :
- University of East Anglia (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet PolySolar (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

π-Conjugated semiconducting organic polymers have gained a widespread interest for their potential application in the fabrication of organic electronic devices. Efficiency of these devices largely depends on the ability of the polymeric film to transport charge; thus attempts are being made to enhance the charge mobility by improving crystallization, aggregation and orientation of the material during the pre-processing. Dip coating, spin coating, doctor blading and thermal annealing techniques are being used for the development of oriented microstructures, however, these techniques are not practicable on a large scale. However, microfluidics is an emerging multidisciplinary field with practical applications in lab-on-a-chip technology. It deals with the precise control, behaviour and manipulation of fluids. It has widely been used for the controlled nucleation and crystallization of small conjugated materials. The aim of this project is to synthesize new soluble conjugated organic polymers by simple solution polycondensation method. The monomers and the resulting polymeric material will be characterized by using the standard techniques. New microchannel system will be designed and fabricated by using polymer, glass or thermoplastics. The polymer solutions will be pre-processed (under optimized conditions like temperature, flow rate or magnetic field) by micro-fluid technique for precise manipulation of crystallization, aggregation and orientation in the solution form. Effect of the variable flow rate, solvent systems and temperatures will be studied. The processed solution will be then spin coated to fabricate prototype dye sensitized solar cell. Atomic force Microscopy, Grazing-incidence wide-angle X-ray scattering, UV visible spectroscopy will used to investigate the aggregation and formation of clusters. Electrical measurements, namely current-voltage (I-V) will be carried out to study the transport properties and cell parameters of the device.

Mots clés : microfluidics, nanostructuration, dssc

Participants :
- Black hole lab (France) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 196707.84 €
Projet EMOTIONS FIRST (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

‘Emotions First’: Neuroscientists have recently discovered the primacy of feelings and emotions over reasoning, in our mental life. On the basis of these results, cognitive scientists are developing a semantics of conceptual classification, grounded on feelings and emotions towards the world. My work for the Marie Curie aims to show that the ancient Greek philosophers developed theories of action, where the battle between our desires and feelings towards the world grounded the pattern of rationality that emerged from this battle. On my reading of ancient philosophy – primarily Plato, Aristotle and the Stoics – the process of reasoning arises from a calculus of feelings and emotions (culminating in love), which aim towards the organism’s good. Socrates held that every human has an innate desire for his or her own good; the human organism struggles to find the good, guided by the desires of the soul. Plato and Aristotle saw the human soul as a locus of desires and motivations, whose contest constitutes deliberation for the good. For both philosophers, the soul’s competing motivations and feelings towards the world result in pleasure, if the competition outcome is successful, and in pain, if not. The successful competition is reasoning, the unsuccessful, miscalculation. I aim to investigate the hypothesis that ‘the emotional quest for the good of the organism is constitutive of rationality’ in an international research-hotbed of ‘emotions in reasoning’, at the Philosophy Centre of Edinburgh University, where philosophy meets cognitive science on ‘emotive lateral thinking’ and on the ‘extended knowledge hypothesis’. The training I can receive at this Center will empower me to present in the best theoretical framework the ancients’ intuition that the calculus of feelings can shed light into the origins of rationality. This is my ambition for the Marie Curie Fellowship.

Mots clés : philosophy of emotions, ancient greek philosophy, decision making, education

Participants :
- University of Edinburgh (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet MINDTHEGAP (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : CLOSED

‘Mind the gap’ is designed to advance our understanding of an important behavioural phenomenon; namely, the frequently observed gap between individuals’ intentions and subsequent behaviours. Such gaps have been widely documented in consumption behaviours and often result in people having a larger negative environmental impact than they themselves want or intend. The fellowship probes the drivers of this phenomenon through in-depth study of two areas of human behaviour, meat consumption and single-use plastics, which have a major impact on our shared environment. Existing research exploring intention-behaviour gaps has largely focused on inter-person variation, examining the influence of individual traits on the likelihood of people reporting these gaps. Far less attention has been paid to the inconsistencies that emerge in a given person’s behaviour over time. In the current work, a novel naturalistic monitoring tool will be designed and employed to examine the time-varying factors interact with individual characteristics in ways that help or hinder people from acting as they intend to. The fellowship will be based at University College Dublin and will involve a secondment to the Organisation for Economic Cooperation and Development. The applicant will benefit from an extended period of ‘training-through-research’ under the supervision of Professor Liam Delaney – a leading behavioural economist with expertise in naturalistic monitoring – and Mr Faisal Naru – a behavioural public policy expert working at the OECD. This will be complemented by courses designed to develop the applicant’s technical skills, including in multilevel modelling and statistical analysis and programming in R. Widely disseminating the Fellowship’s research output will raise the applicant’s profile as a researcher, allow them to build their academic and policy networks, and significantly enhance the work’s impact on the academy, the world of practice and society more generally.

Mots clés : intention behaviour gaps, environmental psychology, meat consumption, single use plastics, daily reconstruction method

Participants :
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 184590.72 €
Projet Genocide accounting (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

“Accounting for genocide” empirically considers two sociomaterial practices of accounting for the 1995 Srebrenica genocide in Bosnia and Herzegovina. First, it scrutinizes efforts of national and international organizations to (ac)count how many Bosniak men were massacred and who was killed in July 1995. The second question about accounting analyses how those politically responsible at the time of the genocide are legally tried at the International Criminal Tribunal for the former Yugoslavia (ICTY). The first practice of accounting is based on inter alia forensic science, statistics, missing persons lists and witnesses conveniently subsumed under ‘atrocity victim identification’ (AVI), the second practice is the domain of adversarial legal proceedings, developing international criminal law, transitional justice and controversies over the Srebrenica genocide and legitimacy of the ICTY. A rigorous qualitative analysis focusing on the various locations—mass-graves, family assistance centres, forensic laboratories, the ICTY, public domain—where objects like remains, missing persons, identities, crimes, DNA evidence, and legal cases come to matter provides a deep understanding of the question of how both practices of accounting become entangled and co-construct each other.


Participants :
- Goethe University Frankfurt (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 159460.8 €
Projet BARRICADE (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

“BARRICADE” is about an evolutionary platform to predict breast cancer (BC) patients outcome and response to therapy in a faster and specific manner. Breast cancer is one of the leading causes of cancer mortality among women and is characterized by a high interindividual variability in response to cancer treatment, and often resistance to therapy arise over the time or after first line of treatment. For this reason, the therapeutic approach of each patient has to be set up during its management causing some gaps, useless toxicities and a losing of time useful for patient’s cure. In cancer research, cells are usually grown in a monolayer on dishes of polystyrene plastic to perform experiment or toxicity studies. Alternatively, researchers use animal models that are able to mimic a more physiological growth of tumor cells and they take in account also the microenvironmental influences. Unfortunately, animal models do not recapitulate the human complexity, and sometimes they do not predict tumor behaviour and clinical response. For this reason, organoids are emerging as new more complex system that may overcome the limitations of traditional cancer model. “BARRICADE” will contribute to taking BC cancer therapy to beyond state-of-art, developing personalized anticancer therapies and giving useful information for cure setting up. Indeed, progress in developing in vitro 3D organoid culture system using primary human breast cancer tissues have attracted great interest as an emerging tools for precision medicine. BARRICADE will help to overcome some of those barriers by giving preclinical information for future therapy settings.

Mots clés : breast cancer, personalized anticancer therapies

Participants :
- Percuros (Netherlands) (Pays-Bas) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 175572.48 €
Projet Face Off (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

“Face Off” is designed as an interdisciplinary project, whose main goal is the first comprehensive investigation and comparison of masking phenomena in the Iron Age Mediterranean (c. 12th-2nd centuries BC), aiming to explain why humans need masks and understand the connection between masks and ancient societies. Apart from focusing on the examination of the Aegean, Cypriot and Phoenician/Punic corpora of masks, this project will use scientific methods (i.e. 3D modelling, pXRF, Face Expression Recognition; Machine Learning) to investigate the transmission of mask models and the impact of ancient masks on the spectators, and to understand the age and gender of the characters represented in these faces, of the persons wearing the masks and of those attending the masked activities. A project on this chronological and geographical coverage and based on such multidisciplinary methodology is unprecedented. Investigating this complexity will provide insights into the role that masks played in some Iron Age communities across the Mediterranean basin. This project is designed to take place at Universitat Pompeu Fabra, which has the expertise, facilities and resources necessary to support such research. By viewing the ancient masks of the Iron Age Mediterranean through the lens of various disciplines and scientific methods, the proposed project entails a significant component of an exchange of knowledge, together with training through research. With its dissemination (seminar, publications) and public engagement activities (articles, lectures, exhibition), this project constitutes an innovative way of doing archaeology and intends to bring together different traditions within the European schools of Mediterranean archaeology.

Mots clés : ancient masks, iron age mediterranean, religion, performances, gender, emotion, spectators, rites of passage, ancestors, superhuman beings, face recognition, machine learning

Participants :
- Pompeu Fabra University (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 160932.48 €
Projet Pro-Membrane (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

“Pro-Membrane” is an extensive project which has been structured to face multiple tasks of different levels of innovation and risk. In its longest-term and most ambitious goal, Pro-Membrane, aims to face the still not solved challenge of stabilize and crystallize Membrane-Proteins (MPs). This study will use, as innovative tool, well-ordered and disordered functionalizable amphiphilic peptoids for structural determinations. Peptoids could indeed succeed where other classes of molecules previously failed, answering to the pressing need of a new method able to establish the specific interactions to stabilize and crystallize each MP. Their peculiar nature helps them to easily cross the membrane and their modular synthesis give access to an infinite combination of molecules. Despite their interest, a systematic and comparative study of their physical properties and self-assembly capacity was never done before. The multidisciplinarity of this work, between Organic Chemistry, Biophysics, and Structural Biology will be achieved through a strict collaboration between all the participants. Training through research and implementation activities have been planned to maximize the candidate’s profile in order to support his career perspectives.

Mots clés : membrane proteins, amphiphilic peptoids, conformational analysis, thermodynamics of hydrophobic interactions, detergents and surfactants, structural studies

Participants :
- Université Clermont Auvergne (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 173076.0 €
Projet ESC (Horizon 2020, appel à projets 2014)
Action : European Researchers' Night
Statut du projet : CLOSED

“Researchers in Real Life” is the project to show people of Aragon, researchers are common people and their work is in our daily life, in a festive mood with activities in City Center streets. After three years European Researchers Night has become an important event in Saragossa. The activities are specifically designed to address public at large and young people. We have previous experience in high involvement of researchers doing activities, and a useful structure program to reach 16.000 attendances. The topics are related with how researchers are in real life, hobbies, sports, and common interests. The event will be a real “Science party” involving most of the reseach entities in Aragon within a tag “Researchers in Real Life” that has become popular for people in the Community. It is remarkable the involvement of the regional stakeholders, which support this European initiative. We work with them to involve new participants and get to more public. Special attention will be paid to promotion of scientific careers to pupils, and we will show researchers in industry and playing different roles; Researchers are everywhere among us. The management team of project will be the same as last editions: Esciencia Eventos Cientificos as coordinator, the University of Zaragoza, ARID Foundation (Government of Aragon), which have half of researchers of Aragon. Cooperating bodies such as The Spanish National Research Council (CSIC), Ibercaja Foundation dependant from main regional bank, and Dinopolis Foundation that manage the Teruel science museum. The consolidated project in Zaragoza will continue its growth because in 2014-2015 Researchers in Real Life will include two new cities in another province (Teruel) within the Community of Aragon, Alcañiz (16,000 inhabitants) in 2014, and Teruel city (35.000 in 2015). This new location will allow us to improve the expected number of people in awereness campaign and the participation rates.

Mots clés : public recognition of researchers, researchers communication, promotion of sciece careers

Participants :
- Fundacion Agencia Aragonesa para la Investigacion y el Desarrollo (Espagne) — Partner, beneficiary, Autres, subvention : 0.0 €
- Universidad de Zaragoza (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Esciencia eventos cientificos sl (Espagne) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 110000.0 €