Projet AiPBAND (Horizon 2020, appel à projets 2017)
Action : Doctoral Networks
Panel : Information Science and Engineering
Statut du projet : CLOSED

The mission of AiPBAND is to train a new generation of entrepreneurial and innovative early-stage researchers (ESRs) in the early diagnosis of brain tumours using molecular biomarkers in the blood, meeting the medical and societal challenges of this emerging field. AiPBAND will focus on gliomas, a range of devastating and progressive brain tumours affecting around 25,000 people each year in Europe and responsible for the majority of deaths from primary brain tumours. Fourteen fellows will be trained by experts in 9 academic and 3 non-academic beneficiaries, belonging to 5 EU member states and 6 partner organizations (4 private sectors and 2 international academic), with fields ranging from neuroscience, engineering (including big data science), healthcare to economics. State-of-the-art technologies will be applied in parallel to (i) identify novel blood biomarkers from patients with gliomas, (ii) design three types of multiplex biosensor (plasmonic-based, graphene-based, and digital ELISA assay-based), (iii) develop a big data-empowered intelligent data management infrastructure, and (iv) develop cloud-based diagnostic systems. Proof-of-concept will be evaluated through clinical trials to assess accuracy, sensitivity and specificity. The elaborately designed individual research projects under the Vitae Researcher Development Framework – carefully arranged into local training courses, network wide events, secondments, personalized career development plans, with strong involvement of the private sector – will ensure exploitation of AiPBAND's achievements, and will maximize the ESRs’ abilities in creative & innovative thinking, triple-i knowledge transformation, and encourage a business-orientated mind-set and entrepreneurship.

Mots clés : cancer, biosensing techniques, molecular diagnosis, biomarker discovery, validation, cloud computing, machine learning, business

Participants :
- Medical trials analysis italy srl (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 306089.4 €
- Hunan University (Chine) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Catania (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 258061.32 €
- B. Braun (Germany) (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- BGI Group (China) (Chine) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- The hyve bv (Pays-Bas) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 255374.28 €
- University of Plymouth (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 599715.07 €
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Partner, beneficiary, Recherche, subvention : 258061.32 €
- Engage (Germany) (Allemagne) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- KU Leuven (Belgique) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 250560.0 €
- Teesside University (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 220148.57 €
- Imperial College London (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 273287.88 €
- Karolinska Institutet (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 263659.32 €
- Stockholm University (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 263659.32 €
- Radboud University Nijmegen (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 56749.84 €
- Biotecture (Pays-Bas) — Partner, organization partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Princess Máxima Center (Pays-Bas) — Partner, beneficiary, Recherche, subvention : 198624.44 €
- Scriba Nanotecnologie (Italy) (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 210033.24 €
- Capital Medical University (Chine) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of London (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 273287.88 €