Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet ADVENTUROUS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

The ADVENTUROUS project, harmonizes with the European Green Deal's 2030 climate targets and the broader EU ambition of reaching carbon neutrality by 2050. It is firmly rooted in the pursuit of catalytic trifunctional systems for the transformative synthesis of sustainable advanced fuels (SAF) derived from renewable feedstocks. The crux of this endeavour rests upon the innovation of two core facets: the integration of catalysts that can seamlessly host diverse catalytic sites and the genesis of an entirely novel synthetic avenue for the production of sustainable aviation fuels (SAF). This project sets forth on a path towards sustainable development, poised to chart a course marked by a near-zero emission CO2 cycle. ADVENTUROUS leverages the expertise of Dr. Camilla Maria Cova in organic synthesis and green synthesis, complemented under the supervision of Prof. Svetlana Ivanova, with broad experience in multifunctional heterogeneous catalysis at the University of Seville (USE). The fruit of this necessary collaboration will be the advanced design and application of a multifunctional catalyst able to revolutionize the biofuel synthesis. What is more advanced technologies such as ultrasound-assisted reactions will be tested for an environmentally sustainable catalyst production and the success of the project will opens a completely new pathways not only to SAF production but also to a numerous starting molecules for fine chemical synthesis. ADVENTUROUS is aligned with the MSCA Green Charter, emphasizing environmental responsibility and sustainable development. By developing sustainable biofuels and innovative catalysts, it contributes to achieving the objectives of decarbonization, energy efficiency, and increased use of renewable energy sources in the transportation sector. Moreover, it addresses key challenges of the current energy landscape, as supply scarcity and environmental pollution, by exploring alternative and renewable pathways for fuel production.

Mots clés : biomass biofuels hydrogenation hmf hydrotalcite valeric acid

Participants :
- Université de Séville (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
Projet PREVAID (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

This project aims to deliver a microfluidic platform capable of isolating bacteria and Extracellular Vesicles (EVs) at high throughput and high recovery rates from clinical samples, and perform the necessary downstream analysis for the diagnosis of diseases requiring earlier/urgent treatment. Currently, long incubation steps required for identification and susceptibility testing of pathogens make clinicians to prescribe broad-spectrum antibiotic treatments in sepsis cases upon hospital admission, and in nearly half of cases this treatment fails. On a different timescale, the lack of symptoms until late stages of some cancer types such as pancreatic cancer means a high mortality rate. Profiling molecules contained in EVs —most importantly DNA, RNA, proteins and lipids— promises a powerful diagnostic tool as biomarkers for cancer, but current EV isolation methods relying on ultracentrifugation are lengthy and can potentially damage the information enclosed. Microfluidics could provide a high yield, high throughput solution for isolation and enrichment of such particles. However, current approaches do not meet requirements of throughput and/or detection limit, and lack insightful physical understanding. I propose to use novel fluid dynamic and electrokinetic models for particle manipulation in microfluidics, with state-of-the-art fabrication methods to deliver a device capable of rapidly isolating and enriching samples containing (a) bacteria at low concentration (few hundreds per mL) to be integrated in a platform with the potential to identify and perform ASTs in possible bacterial infections in body fluids that avoid culture steps in current gold standards and potentially allow a ten-fold time reduction from sample to answer; (b) EVs to replace current ultracentrifugation methods. Thus, a future clinical implementation of the project outcomes will have large economic and societal impact.

Mots clés : bioparticle separation, lab chip, fluid dynamics, electrokinetics, bacteraemia, extracellular vesicles

Participants :
- Université de Southampton (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Séville (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 165312.96 €
Projet OpenMag (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

There is a great need for new energy-efficient technologies to meet the ever-increasing energy demands of the 21st century. The field of magnonics aims to address this need by developing nanoscale magnonic devices that use magnons - the excitations of magnetic materials - as information carriers. Because magnons do not require electric currents, they are much more energy efficient than electron-based technologies. However, the transport of magnon signals over long distances remains a key challenge, limiting the development of a mature magnonics platform. The central objective of the OpenMag project is to meet this challenge by harnessing the coupling of magnons to their environment. This renders the magnon transport non-Hermitian, opening up pathways to engineer the enhancement of magnon transport. OpenMag will thus open up the field of non-Hermitian spintronics: the study of the spin degree of freedom in non-Hermitian systems. This will be accomplished through two strategies: (1) the interaction of magnons with photons in a cavity and (2) the development of non-Hermitian magnon topological phases through magnon-electron interactions. These strategies will initially be developed in ferromagnets, which allows OpenMag to make use of their well-understood magnetization dynamics. Using insights from ferromagnetic materials, OpenMag will develop non-Hermitian spintronics in antiferromagnets and altermagnets, which will enable access to fast dynamics and downsizing to the nanoscale: two crucial milestones in magnonics.  The OpenMag project will be carried out at the Johannes Gutenberg University (JGU) Mainz, under supervision of Prof. Sinova, who leads a world-renowned theory group in spintronics and nanoelectronics. Over the past decades his group has developed the theoretical foundations of antiferromagnets and altermagnets, and is thus the perfect host for building the field of non-Hermitian spintronics in antiferromagnets and altermagnets.


Participants :
- Université Johannes-Gutenberg de Mayence (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 189687.36 €
Projet STECALMY (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : CLOSED

Mercury (Hg) is a volatile element that is used for industrial and technological applications and can be potentially toxic for any ecosystem. In Earth science, its accumulation in sedimentary sequences has been recently used to link the major Phanerozoic climatic and biological crisis to massive volcanic events. This is because volcanic degassing is the main mechanism that releases Hg to the atmosphere. While these aspects are receiving increasing scientific interest, it is still unclear what is the source from which a volcanic system acquires its Hg content prior to magma degassing. The few studies addressing the behaviour of Hg in the deep Earth appear to have adopted sample preparation and analytical procedures that might have unintentionally under- or overestimated the actual Hg contents in the rock samples. Project STECALMY seeks to understand the source and mobility of Hg in the Earth's crust by studying the Sesia Magmatic System (SMS), western Southern Alps, Italy, an exposed continental magmatic system that can be tracked from its deepest roots up to its volcanic products. Through a rigorous sample preparation procedure and by testing different analytical methods, I will firstly develop a methodological and analytical protocol that optimises the analyses of Hg in crystalline rocks. Such protocol will then be used to investigate the Hg content in carefully selected rocks from the SMS, from the uncontaminated and undegassed magmatic rocks to the metamorphic rocks of the crust in which they emplaced and the volcanics erupted to the surface. This will be combined with petrography and major and trace element geochemistry of the same samples, in order to quantify the gain or loss of Hg in magmas during assimilation, crystallisation and degassing in a continental setting. Project STECALMY will produce the first methodologically-robust model on the source and mobility of Hg within a continental magmatic system.

Mots clés : mercury magmatism continental crust sesia magmatic system, thermodynamic modelling

Participants :
- Université de Trieste (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172750.08 €
Projet SupraBioElectris (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Cardiovascular diseases, including ischemic heart disease, are the leading cause of death in Europe. Cardiac tissue that has been lost by injury cannot be naturally regenerated, which leads to heart failure. To help repair heart, biomaterials-driven approaches, especially hydrogels in combination with carbon nanotubes (CNTs), are among the most promising strategies. However, existing CNT- based hydrogels provide a simplistic reflection of structural and functional features of the native cardiac tissue. A solution lies in mimicking the native tissue from multiple angles: bioadhesion, viscoelasticity, mechanical properties, electroconductivity, 3D supramolecular and hierarchically ordered fibrous structure. SupraBioElectris aims to develop novel supramolecular biomimetic and electroconductive nanocomposite hydrogels by exploiting the concept of branching, widely occurring in nature. The key players in this project are thus branched CNTs and supramolecular, biomimetic short peptides-based hydrogels. The union of these contrasting components constitutes an innovative approach, making use of their strengths to reach the required multi-faceted biomimicry. The hypothesis is that the combination of these components will create smart and multifunctional biomaterials, able to boost and support electrical activity of cardiomyocytes and thus aid in heart repair. Furthermore, advanced, state-of-the-art material characterization tools will be used to study nanocomposites with nanoscale spatial resolution, ensuring optimal material design and function. SupraBioElectris project therefore addresses one of the major health challenges and will highlight the importance of using supramolecular structures in the design of biomimetic materials. The project is highly interdisciplinary and international. It will also shape the researcher into a leading expert in hydrogels, by expanding his existing expertise via tailored training and acquisition of new skills.


Participants :
- Université du Colorado (system) (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Trieste (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172750.08 €
Projet chelOMICS (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Outbreaks of bacterial diseases pose a persistent challenge to fish farming around the world causing significant economic loss. To improve efficiency, safety, and sustainability of aquaculture new health monitoring and rapid disease diagnostics approaches are required. Here, we propose an ambitious multidisciplinary project that implements modern multi-omics tools, in particular metabolomics and metagenomics, to provide a holistic understanding of host-pathogen interactions in farmed fish in the context of three major bacterial diseases; vibriosis, photobacteriosis, and furunculosis. This project will focus specifically on the metabolome of siderophores, iron chelating microbial metabolites that are key virulence factors during infection, and their use as biomarkers for early disease diagnostics. In nature, microorganisms exist in diverse communities and therefore infections can be caused by a combination of species yet the involvement of co-species in disease progression is poorly understood and represents a great diagnostic challenge. I have gained extensive skills in metabolomics through my PhD in Australia and postdoctoral experience in Germany. This project will enable me to go one step further; I will use different bioinformatic tools as well as imaging analytical chemistry (MALDI-IMS) approaches to integrate metabolomics and microbiome data and answer important ecological questions in aquaculture. I am highly motivated to take on this new challenge and acquire new scientific and transferable skills, which will strengthen my profile as an independent researcher and increase my opportunities for a permanent position after the fellowship.

Mots clés : siderophores, multi omics, aquaculture diseases, disease diagnostics, holobiont concept

Participants :
- Université de La Corogne (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 181152.96 €
- Société Max-Planck pour le développement des sciences (Allemagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université Griffith (Australie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet DIRAQUM (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Technology in photonic quantum information processing and quantum computing is advancing rapidly, requiring more efficient and precise control of the generation of quantum states of light. Over the past decade, semiconductor quantum dots (QDs) have emerged as near-perfect photon sources with unprecedented photon emission rates compared to other technologies. However, two key factors, photon indistinguishability and extraction efficiency, are critical for practical applications such as multiphoton interferometric experiments, quantum computing and boson sampling. Achieving both high photon indistinguishability and extraction efficiency from any quantum light source is challenging due to inherent trade-offs between precise control of photon properties and efficient collection, as well as technical and material limitations. Various photonic structures (such as cavities and metamaterials) have been used to improve the extraction efficiency of the emitters, but they often introduce complexities that adversely affect photon indistinguishability. Imperfections such as etched surfaces around QDs can lead to unwanted effects like an unstable charge environment due to exposed crystal bonds and surface interactions, ultimately degrading photon indistinguishability. To address these issues and improve performance, a promising alternative approach is to integrate quantum dots with Dirac photonic metamaterials. Within these metamaterials, topological states can emerge as protected edge states, which are known to be resilient to disorder and imperfections. Furthermore, Dirac photonic metamaterials lead to enhanced light-matter interactions, allowing a dramatic increase in spontaneous emission and the manipulation of chiral photon modes. The overall aim of this project is to combine quantum dots (InGaAs) with Dirac photonic metamaterials to achieve specific goals, including high photon indistinguishability, efficient photon extraction and tailored single-photon emission.

Mots clés : quantum dot, single photon sources, photonic metamaterial, dirac cone, quantum optics

Participants :
- Université de Wurtzbourg (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 173847.36 €
Projet WAYSIDE (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Psychosocial disability (PD) refers to ‘disabilities that arise from barriers to social participation experienced by people who have or who are perceived to have mental conditions or problems’ According to the World Health Organization, mental, neurological and substance use disorders (MNS) account for more than 10% of the global disease burden of disease and are responsible for 1 in 5 years lived with disability. The global loss of productivity on account of depression and anxiety is estimated to cost the global economy US$1 trillion each year. In low- and middle- income countries, more than 75% of people with MNS receive no treatment at all for their disorder. In Kenya, unmet need for mental health services (MHS) is worse in young persons compared to adults. Further, poverty and adversities are causes and consequences of poor mental health and persons with PD experience discrimination in mental health service, employment, and social life that affect wellbeing and life expectancy. Mental health services in Kenya are sparse and elude most persons with PD. Access to available MHS is limited by lack of information about where and how to access it, and discriminatory delivery of services. In recognition of the dire need for inclusive mental health services, a recent interagency Government of Kenya Taskforce on Mental Health in 2021 declared mental ill-health in Kenyan society as a national public health emergency. Also, strengthening the Mental Health system is the fourth strategic objective of the Kenya Mental Health Action plan 2021-2025. This project responds to this need (identified by GOK taskforce) and aligns with the WHO’s vision of a world where ‘all people achieve the highest standard of mental health and well-being’. The overall aim of this project is to develop and pilot a support framework for an inclusive mental health system using digital technologies to promote wellbeing, work, and employment for young persons with PD in Kenya.

Mots clés : wellbeing, work and employment, psychosocial disabilities, inclusive mental health system, digital technologies

Participants :
- University College Dublin (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 281970.72 €
- Université de Nairobi (Kenya) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet CLIMAGECARE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

CLIMAGECARE explores ageing social care and older people's care experiences in the context of the climate crisis in villages on the Spain-Portugal border. The border and rural areas of Spain and Portugal share environmental and social conditions that impact the care of older people because depopulation processes and the lack of care policies in social and health programmes are causing a care crisis, and the current climate crisis is increasing the number of forest fires and the temperatures in these border areas, which mainly affect the ageing population. This project adopts a critical and reflexive approach to understand how ageing care is delivered in these rural border areas in a context of climate crisis. It analyses: (1) ageing social care in relation of the primary health system, community and families in the context of climate crisis events such as forest fires and increased temperatures, and (2) the daily care experiences of older people in the context of climate crisis events and their cultural construction of care and self-care based on their relationship with local care actors and the non-human environment. The design of CLIMAGECARE is grounded in empirical and interdisciplinary research, crosscutting the fields of care studies, environmental studies and medical anthropology to understand the dynamics of the relationships between ageing care and the climate crisis. The project will use qualitative research methods and a co-creation approach in two villages on the central Spain-Portugal border to answer the research questions.

Mots clés : climate crisis, environmental anthropology, ageing, social care, rural spaces, co creation research

Participants :
- Centre for Research in Anthropology (Portugal) — Coordinator, beneficiary, Recherche, subvention : 279166.56 €
- Institut universitaire de Lisbonne (Portugal) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Monash (Australie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet PlioCaudates (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Environment and Geosciences
Statut du projet : SIGNED

Caudates, one of three extant lineages of amphibians, are a rich and diverse clade that rely heavily on water for reproduction and development and are known to be important palaeoecological indicators. Records indicate that less than 10% of Neogene caudates are known to be preserved as articulated skeletons, and in Lagerstätte type of preservation is even rarer still. This study will investigate caudates from the Camp del Ninots Lagerstätte using micro-computed tomography scans (μCT) to build a taxonomic framework and use three-dimensional geometric morphometrics to analyse shape differences for phylogenetic/taxonomic value. This study will also compare morphological shape differences using μCT of caudates from different sexes and determine whether there are sexual dimorphic morphological characters within Spanish caudates. Morphological characters and genomic data will be combined to identify Pliocene aged caudates recovered from the Camp del Ninots Lagerstätte using Bayesian phylogenetics, which will provide time-calibrations of when the Spanish fossil caudates originated in comparison to extant congeners. Caudates identified by Bayesian phylogenetic methods will then act as fossil calibration points to phylogeographically determine how caudates dispersed spatio-temporally into Spain from Africa or the rest of Europe. It is hoped that this research can improve our understanding of caudate evolution in the Neogene, but also how we can project caudate responses to climatic change in the future and mitigate biodiversity loss.

Mots clés : caudata phylogeography phylogenetics geometric morphometric analysis palaeobiogeography micro computed tomography palaeoclimatology palaeoecology spain lagerst tte

Participants :
- CERCA Institution (Espagne) — Coordinator, beneficiary, Recherche, subvention : 209914.56 €
- Université Monash (Australie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €