Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet NEOTERP (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The project concerns the development of innovative methodologies for the synthesis of novel bioactive natural products (meroterpenoids) and their potential application for the discovery of new medicines to treat resistant cancers and resistant microbial infections. The fundamentals of its originality and innovation are: a) The synthesis of a focused library of novel bioactive meroterpenoids, planned to have an impact in the fields of anticancer and anti-infective medicinal chemistry. b) The application of a flexible and concise dual biomimetic synthetic strategy, which will significantly impact the field of natural products synthesis focused on drug discovery. c) An extensive use of novel methods for polyene cyclisation including processes based on sulfite, sulfate, phosphate and other electrophilic initiators including radical cations generated by photoredox catalysis, coupled with polyketide aromatisation, will greatly impact in the field of cyclisation cascades in general as well as meroterpenoids synthesis. Dr Fabbrizzi is an experienced experimental scientist with substantial academic and industrial experience whose research career was interrupted in October 2015 due to funding crises in Italy. The award of a H2020 fellowship, if this proposal is successful, will be critical in supporting the resumption of his independent research career. Working in the supportive environment of Imperial College under the expert guidance of professor Barrett he will considerably reinforce his knowledge of natural product synthesis and drug discovery and will resume his position in the European research community improving his profile to face the current challenges of organic and medicinal chemistry. keywords/descriptors: Synthetic organic chemistry, Natural product synthesis, Medicinal chemistry


Participants :
- Imperial College London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet MEDLEM (Horizon 2020, appel à projets 2015)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : CLOSED

The project entitled: “Cost-effective microfluidic electronic devices for optimal drug administration based on fractional pharmacokinetics for leukemia treatments”, with acronym MEDLEM, has a general objective to foster exchanging knowledge and sharing different culture and approaches in reaching high level of excellence, in research and innovation, in the framework of this field. The project is aimed at strengthening research collaboration through active networking, staff exchange and dissemination activities between 4 European organizations from Serbia, Germany and France as well as 2 non-European institutions from Thailand and Australia, in linking the fields of microfluidic electronic devices, optimal drug administration, fractional pharmacokinetics, and leukemia treatments. The project will exploit complementary competencies and synergies of the participants, and enable knowledge sharing via international/inter-sectoral mobility, based on secondments of research staff. The consortium offers a unique opportunity that creativity and entrepreneurship will flourish and will help exchanged personnel to turn creative ideas into innovative electronics products, reaching breakthroughs in modelling, drug administration and improvements in therapy protocols. The main technical goals of the joint research programme are: - Development of fractional pharmacokinetic models and procedures for parameter identification within these models; - Design and fabrication of microfluidic device with in-built electronics for optimal drug delivery protocol; - Pharmacokinetics determination of the pharmaceuticals for leukemia treatments and its testing in vitro and in vivo systems; - Optimal control problem, its numerical solution and implementation. The proposal will develop new research links and strengthen the current research links among the partners and will help build up long-term, world-class research in more successful leukemia treatments.

Mots clés : rapid prototyping, fractional pharmacokinetic, leukemia treatment

Participants :
- Marcotech ohg marketing, controlling and technology management (Allemagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 40500.0 €
- University of Novi Sad (Serbie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 166500.0 €
- Prince of Songkla University (Thaïlande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Curtin University (Australie) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Elvesys (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 45000.0 €
- Genochem (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 31500.0 €
Projet UCONCRI (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The project examines the tension between social heterogeneity and universal principles for political action and judgment through a comparative reading of the work of Jean-Francois Lyotard and the Frankfurt School tradition of critical theory. Frankfurt School critical theory and agonistic political theory influenced by French philosophy are predominantly read as two separate and mutually exclusive perspectives in political philosophy. This project traces a series of explicit and implicit discussions between Lyotard and the Frankfurt School in order to read both perspectives as different yet interrelated. The connections and contrasts between both perspectives are then used to develop a new framework to address three central issues within critical theory and political philosophy more broadly. Specifically, the project pursues three specific objectives: 1) To assess the possibilities and limitation of consensus and dissensus as grounds of universal political action and judgment, by means of a contrast between Lyotard and Habermas; 2) To understand the causes of social conflict as well as the role of critical theory is their articulation, by means of a contrast between Lyotard and Honneth; 3) To explain the sources of ideological extremism and determine the capacity of critical theory to respond to it, by means of a contrast between Lyotard and Adorno. Relying on a comparative methodology that involves intertextual reading, genealogical analysis, and intellectual history, the research will illuminate and generate dialogues between perspectives that are often considered separately from one another, thus improving our understanding of universality, conflict, and critique in heterogeneous societies.

Mots clés : critical theory frankfurt school lyotard postmodernity agonism universality conflict

Participants :
- Université de Strasbourg (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 184707.84 €
Projet RENESENG II (Horizon 2020, appel à projets 2017)
Action : Staff Exchanges
Panel : Information Science and Engineering
Statut du projet : CLOSED

The project goal is to further advance the emerging area of Bio - process - systems engineering (BPSE) by capitalizing the recent advances and ITN of RENESENG (FP7 - PEOPLE - ITN) toward the following project objectives : - Expanding the knowledge for value chains across feedstocks, products and industries, e.g., by looking into the potential of MSW (including food waste) energy chemicals nexus. - Investigating the area of knowledge management (i.e., data structures, workflows, protocols) for the effective communication across the diverse academic research scales and industrial applications (i.e., lab to unit operations, to process and plant design, to business development, sustainability assessment). - Applying the existing RENESENG tools, models, methods, know how as well as the newly developed in this project to emerging topics of bioeconomy and links to circular economy, with special focus on various forms of “waste” biomass (e.g., MSW, glycerol, lignin). Enhancing the network with new aca demic and non academic partners and significantly contributing via meaningful secondments to the career development of ESR and ER.


Participants :
- Greene waste to energy sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 18000.0 €
- Chimar Hellas (Greece) (Grèce) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 9000.0 €
- Wageningen University & Research (Pays-Bas) — Partner, beneficiary, Recherche, subvention : 0.0 €
- University of Surrey (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 94500.0 €
- Board of the Swiss Federal Institutes of Technology (Suisse) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 22500.0 €
- Bioprocess pilot facility bv (Pays-Bas) — Partner, beneficiary, Autres, subvention : 0.0 €
- Arkema france (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
- Ibj technology aps (Danemark) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 27000.0 €
- Imperial College London (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 36000.0 €
- National Technical University of Athens (Grèce) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 117000.0 €
- Chalmers University of Technology (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 63000.0 €
- Cie industrielle matiere vegetale (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 9000.0 €
- Vishwamitra research institute (Etats-Unis) — Partner, organization partner, Autres, subvention : 0.0 €
- Technical University of Denmark (Danemark) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 36000.0 €
Projet NewCat4Bio (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The project is focused on the preparation, characterization and application of (hydro)thermally stable, homogeneous, and porous metallosilicate catalysts. As a synthetic route we will apply non-hydrolytic sol-gel routes since they produce materials with high homogeneity and they allow the one-step functionalization of the oxides surface. We will focus and demonstrate our results primarily on the synthesis of alumosilicates, and then broaden the work to Zr-, Ti-, Nb-, and Ta-doped silicates. We will use advanced analytic techniques for the characterization of heterogeneous catalysts – infrared spectroscopy, solid state nuclear magnetic resonance, nitrogen and ammonia adsorption-desorption experiments, electron microscopy, powder x-ray diffraction, small angle x-ray scattering, and surface analytical techniques – time-of-flight secondary ion mass spectrometry and x-ray photoelectron spectroscopy. We will evaluate our materials as catalysts in alcohol dehydration. For this type of reaction it is desirable to have hydrothermally stable acidic material. Hydrothermal instability is usually the main drawback of mixed metal oxides. Therefore we will tune the hydrophobicity of prepared materials and their surfaces by introduction of various organic groups in order to improve their performances. We will focus on the control of the pore size distribution as well and prepare stable and homogeneous materials with large pores applicable in catalytic actions on bulky (bio)molecules. In such a way the project will establish fruitful cooperation between the two research groups – one focused primarily on the synthetic pathways to novel materials and the second focused on their application in heterogeneous catalysis. The fellow will learn new characterization techniques and catalytic testing under industrially-relevant conditions. He will work independently, attain new soft skills and will prepare for the establishing of new research group back in Brno.

Mots clés : non hydrolytic sol gel, non aqueous sol gel, porous mixed oxides, alumosilicate, hydrophobicity, homogeneity, porosity, heterogeneous catalysis

Participants :
- Université Catholique de Louvain (Belgique) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172800.0 €
Projet CATAPULT (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Physics
Statut du projet : CLOSED

The project is one of an interactive synergism between theoretical modelling at UC Berkeley's MSE department and the CNRS-LEM and multiple length-scale structural/mechanical characterization and innovative processing at UCB. The researcher will lead the project under the supervision of Pr. Asta (UCB) and Dr. Finel (LEM). The work will be done in strong collaboration with Dr. Devincre (LEM) and experimentalist Pr. Ritchie (UCB). As structural materials reach their performance limits, one of the major scientific challenges for the 21st century is the development of new lightweight, high-performance structural materials to support advances in diverse strategic fields from building to transportation or energy. Tomsia and Ritchie have designed a freeze-casting technique to synthesize materials that closely mirror the hierarchical microstructure of nacre, producing the highest toughness ceramics on record. Now, our goal is to improve the material strength as well as toughness. Preliminary results have been recently obtained in the form of Al2O3/Al-Si composites exhibiting high toughness but a strength still 30% lower than pure metal. Our project aims to identify, characterize and model the material fracture, involving physical processes at many length scales and, finally, to design hybrid material with optimized mechanical properties. Our efforts to define the scientific mechanisms needed to develop such new damage-tolerant materials will follow an innovative multi-scale approach: combination of first-principles modelling of the interfaces and micro-mechanics models of bulk elastic and plastic relaxation, together with experimental data.

Mots clés : metal ceramic composite, bio inspired material, mechanical properties, fracture resistance, interface toughness, atomistic modelling, meso plasticity modelling, dislocation dynamics, phase field model

Participants :
- University of California System (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Centre national de la recherche scientifique (France) — Coordinator, beneficiary, Recherche, subvention : 178722.6 €
Projet DISIPO (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

The project presents a novel concept that combines Power to Gas (PtG energy storage) and oxy-fuel combustion (carbon capture) to decarbonise carbon-intensive industries (iron/steel as case study). PtG consumes renewable electricity to produce H2 (stored energy) and O2 (byproduct). This O2 is fed in the oxy-fuel furnace in the iron industry to attain a high concentrated CO2 stream, thus avoiding the energy penalization of requiring an air separation unit. Besides, the stored H2 and the captured CO2 are combined via methanation to produce synthetic natural gas to be used in the industry or distributed through the gas network. The overall objective of the project is to reach TRL 2 in the novel PtG–Oxy-fuel–Iron/Steel concept through the following research objectives: 1) To design, simulate and optimize the integrated layout of the novel concept, 2) To assess the maximum CO2 abatement under a proper operational strategy adapted to the industry and the availability of the renewable energy resource, and 3) To compare the concept with iron/steel industries operating with conventional CCS, under economic and life-cycle analyses. The training covers 1) simulation of energy intensive industries, 2) market and industrial criteria and constrains for adopting new technologies, 3) life-cycle assessment and 4) horizontal skills through a wide-ranging programme of activities. These objectives will be reached through a mobility period in Waseda University supervised by Prof. Nakagaki (over 20 years of experience in the topic and 71 patents in collaboration with industry) and a secondment to K1-MET (Austrian Competence Centre for Advanced Metallurgy, driven by the Austrian steel industry). The project is relevant for MSCA due the extensive planned training aimed to gain skills and maturity as researcher, and also because the proposed concept allows recycling CO2 in carbon-intensive industries whose emission-causing processes cannot be replaced with direct electrification.

Mots clés : power to gas, industrial decarbonisation, oxy fuel combustion, renewable energy, energy storage

Participants :
- Waseda University (Japon) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Universidad de Zaragoza (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 188442.24 €
Projet MASSIF (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : TERMINATED

The project proposal MASSIF aims at improving the fundamental understanding and control of interfaces of a battery type based on Li active materials all solid state batteries (ASSLB). The main objective is the investigation and optimization of the interfaces developing between the solid electrolyte and the electrochemically active material particles electrodes. The acquired knowledge would allow the design of optimized interfacial layers (also called artificial Solid Electrolyte Interfaces, art-SEI) capable of warrant stable interfaces. The art-SEI should allow intimate contact between the active material and the conductive particles. Our research program involves hybrid electrolytes in combination with solid state electrolytes (SSE); this approach proves to be useful to generate an art-SEI. We are going to pay attention to the positive electrode-solid electrolyte interface, which has been studied as much as the metal Li solid electrolyte interface. With this in mind, they are going to use Li2S as a positive electrode, and the last task of the project will develop a full cell using Si as a negative electrode. Si was selected as a negative electrode to avoid the problems related to Li; it is known that Li reacts with most of the SSE. The project also takes in to account the training of the researcher and the career development plan to achieve the goals and independence of the researcher. The interdisciplinary and network of the host institution will be also used to push the career of the researcher forward.

Mots clés : solid electrolyte interface, li2s, battery

Participants :
- Karlsruhe Institute of Technology (Allemagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 162806.4 €
Projet AUTOIGG (Horizon 2020, appel à projets 2017)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

The project proposes to organize the exchange of staff of three Academic institutions from Serbia (coordinator), Turkey and Finland, two SMEs from France and Turkey and three TC institutions (two from USA and one from Costa Rica) towards the production of an innovative automated multifunctional device for diagnostics of neurodegenerative diseases. The objectives addressed will be: • Development of experimental cellular models and procedures with immunoglobulins (IgGs) from patient sera as diagnostic and prognostic technologies related to neurodegenerative diseases (particularly based on studies of amyotrophic lateral sclerosis - ALS). • Defining mark-up characteristics of the standardized in vitro approach for personalized diagnostic protocols. • Design of a small-scale platform based on automated fluorescence microscopy. These objectives are based on previous studies on ALS of the coordinators group, however the project also proposes to study the applications on other neuroinflammations and neurodegenerative conditions. This addresses a relevant R & I as well as a socioeconomic medical issue. It is the right timing for addresing this research chalange towards application by means of networking that will deal with interesectorial and international exchange of expertise. In addition, three workshops and two training schools will be organized followed by an elaborate dissemination programme. Carrier plans will be designed for the seconded staff in order to maintain the sustainability of the Action.

Mots clés : amyotrophic lateral sclerosis, astrocytes, immunoglobulins, calcium, voltage sensitive dyes

Participants :
- Argenit akilli bilgi teknolojileri sanayi ve ticaret limited sirketi (Turquie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 94500.0 €
- Northeastern University (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Elvesys (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 9000.0 €
- Fundacion centro de alta tecnologia (Costa Rica) — Partner, organization partner, Recherche, subvention : 0.0 €
- University of Eastern Finland (Finlande) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 36000.0 €
- University of Connecticut (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Belgrade (Serbie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 693000.0 €
- Yeditepe University (Turquie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 121500.0 €
- University of Chicago (Etats-Unis) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €