Projet CardioSCOPE (Horizon Europe, appel à projets 2021)
Action : Staff Exchanges
Panel : Life Sciences
Statut du projet : SIGNED

The CardioSCOPE proposal aims to bring together experts from Companies and Αcademia throughout Europe to exchange and expand their expertise on interdisciplinary approaches, to enhance the Research and Innovation capacity of Europe in the field of cardiovascular diseases. Connecting and expanding Europe-wide biobanks and expertise through a comprehensive multiomics approach for the discovery of novel pathological players, CardioSCOPE will give deeper insights into acute coronary syndrome (ACS) development and progression towards major adverse cardiovascular events (MACE). We will use well-defined prospective cohorts to discover and validate novel genomic, transcriptomic, proteomic and metabolomic signatures specific for ACS and MACE, to be combined in multimarker models by machine learning/artificial intelligence algorithms, enabling more accurate ACS diagnosis and MACE prediction. This excellent research network aims at building scientists competent for the upcoming “omics” era by training and knowledge transfer. Specific research skills not available at home institutions will be acquired through individually designed secondment plans, training schools, webinars and short-term courses. Intersectoral activities will improve entrepreneurial skills of consortium staff and facilitate transformation of scientific breakthroughs into commercially available products/services. CardioSCOPE includes experts with a wide clinical and research experience, access to patients with ACS and the expertise required for achieving set goals. World-class institutions gathered within this consortium (from 6 countries: 7 academic, 4 companies, 1 hospital) offer specific expertise, state-of-the-art equipment and adequate human resources to address these challenges. In summary, the results of this project will transcend our own scientific interests to enable a transfer of knowledge into a multidisciplinary environment and achieving significant impact on ACS management and policies in Europe.

Mots clés : multiomics, multimarker models, acute coronary syndrome, artificial intelligence, algorithm

Participants :
- Université de Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 184000.0 €
- Klinicko-bolnicki centar dr dragisa misovic-dedinje (Serbie) — Partner, beneficiary, Organismes publics (hors enseignement & recherche), subvention : 82800.0 €
- Université de Belgrade (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 280600.0 €
- Biosfer teslab sl (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 87400.0 €
- B.s.n. biological sales networks.r.l. (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 55200.0 €
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 124200.0 €
- Genetic lab srl (Roumanie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 41400.0 €
- Université d'Ulster (Royaume-Uni) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Romanian Academy (Roumanie) — Partner, beneficiary, Recherche, subvention : 299000.0 €
- Université Rovira i Virgili (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 41400.0 €
- Fondazione Bruno Kessler (Italie) — Partner, beneficiary, Recherche, subvention : 92000.0 €
- Université de Crète (Grèce) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 230000.0 €