Projet DRYNET (Horizon 2020, appel à projets 2016)
Action : Staff Exchanges
Panel : Environment and Geosciences
Statut du projet : CLOSED

The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.

Mots clés : anhydrobiosis, cell, germplasm, low cost, environmental friendly biobanking

Participants :
- BioTalentum (Hungary) (Hongrie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 171000.0 €
- IMAGENE (France) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 4500.0 €
- University of Burgos (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 148500.0 €
- Biobanking and Biomolecular Resources Research Infrastructure Consortium (Autriche) — Partner, beneficiary, Recherche, subvention : 0.0 €
- University of Cagliari (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 112500.0 €
- University of Teramo (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 238500.0 €
- Avantea (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 27000.0 €
- University of Modena and Reggio Emilia (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 63000.0 €
- Chulalongkorn University (Thaïlande) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- National Agriculture and Food Research Organization (Japon) — Partner, organization partner, Recherche, subvention : 0.0 €