Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet MSP (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Owing to availability losses and the tremendous associated costs, improvement of the understanding of deposition mechanisms in boiler tubes is defined as a high priority in power industry. The electrostatic interaction between the suspended colloidal particles of corrosion products and the metal wall surface is the crucial factor that determines the deposition process and influences their deposition rate. The proposed project suggests a new approach to reduce the deposition by altering the surface characteristics of the suspended particles, potentially forming deposits, increasing the electrostatic repulsion between the particles and the inner boiler tube wall. Magnetite is a most profuse deposit compound.The main objective of the proposed project is to determine the effect of octadecylamine, oleylamine, oleyl propylenediamine, acetate, formate, glycolate, propionate, and aluminium on magnetite surface charge, zeta potential and the deposition rate at high temperatures. The surface charge and zeta potential are the key parameters that control colloidal stability of particles and their deposition on the boiler tube walls. Experiments will be carried out under different operating conditions (T,P, water chemistries) which simulate the plant water steam cycle conditions. The zeta potential measurements will be performed in the range of 25 to 80 oC employing the electrophoresis technique, the surface charge between 25 and 290 oC using the acid-base potentiometric titration and the deposition rate measurements between 25 and 150 oC using QCM-D. The parameters describing the magnetite surface in various conditions will be obtained. The research will result in the establishment of relations between the solution composition and the chemistry of the colloidal particles over a broad range of temperatures. The obtained results will serve as a basis for the development of tools to reduce the boiler tube failures and enhance the reliability and performance of the power plants.

Mots clés : power plant chemistry, power plant water steam cycle, water technology, energy, tube fouling, thermal power plant, boiler tube deposits, power generator, magnetite surface properties

Participants :
- Delft University of Technology (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 165598.8 €
Projet PeroVIB (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Owing to the “soft” nature of perovskite lattice, structural deformations (vibrations) play a crucial role in modulating the electronic dynamics of perovskites. In fact, one may engineer the key optoelectronic properties of this class of materials by tuning the coupling strength between photoexcited charge carriers and lattice phonons. Experimental realization of such vibronic coupling in the compositional space of perovskites remains so far unexplored. Herein through this project, I aim to identify the crucial vibrational modes of hybrid perovskites (of various compositions and dimensions) that influence the electronic dynamics and charge transport in real electronic devices of them. To address this fundamental problem, I plan to develop double-resonant excitation (infrared pre-excitation prior to electronic excitation) based "Vibrationally Promoted Electronic Resonance" spectroscopic technique that will give a direct access to monitor the vibrational dynamics of organic and inorganic sub-lattice in the electronically excited state of the hybrid perovskites. This technique is specifically proposed here for probing the vibronic coupling of these soft materials with high mode-selectivity. We will further explore pump-push photocurrent spectroscopy on real functional electronic devices of those perovskites to identify the role of structural fluctuations in modulating the charge transport efficiency. This unique hybrid spectroscopic approach will provide wealth of information from fundamental structural dynamics to device performance; which will enable us to develop design rules of structure-function relationship to maximize the efficiency of perovskite devices. This research program will not only provide an opportunity to enhance my research skills, which in turn will facilitate to launch my independent research group in future but also outcome of the project will advance the current research field by replacing the current assumptions with the experimental findings.

Mots clés : hybrid perovskites, ultrafast spectroscopy, photocurrent spectroscopy, polaron, lattice vibrations, carrier phonon coupling

Participants :
- Imperial College London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 224933.76 €
Projet UnravelOxStress (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Oxidative stress -the imbalance between antioxidants and reactive oxygen species (ROS) generated during aerobic respiration- has often been hypothesized to play a central role in disease and life history evolution, including ageing. However, whether oxidative stress modulates patterns of growth, reproduction and survival is still an enigma, largely because the high reactivity of ROS makes oxidative stress difficult to measure. In addition to this, the experimental manipulation of oxidative stress levels without toxic side-effects has also proven difficult. I propose to elucidate oxidative stress effects on (cellular) ageing and key fitness components using a novel non-invasive experimental approach that bypasses side effects of pharmacological approaches. To this end, I will expose birds to hyperoxic air, which is known to increase oxidative stress. This will be combined with alleviation of oxidative stress through the administration of antioxidants in a 2x2 design, to verify that the observed effects of hyperoxia can be attributed to oxidative stress. First, I will test the effect of both interventions on sexual ornamentation, sperm quality and future reproduction using captive adult zebra finches. Second, by applying the same 2x2 design to nestlings I will test how oxidative stress affects future reproduction and cellular ageing (telomere attrition). The latter aims to resolve the long-standing question whether the effect of oxidative stress in vitro is also observed in vivo, at physiological oxidative stress levels. In this way, this Action will shed light on the conundrum of the roles of oxidative stress in life history evolution and telomere dynamics. Moreover, through mutual knowledge transfer and the extension of my scientific network (both in the host institution and through dissemination events that I will organize around Europe), this Action will critically advance my career towards the establishment as independent researcher.

Mots clés : oxidative damage, antioxidant protection markers, carotenoids, melanins, ornamentation, early life conditions, vitamin supplementation, fecundity, sperm quality, taeniopygia guttata

Participants :
- University of Groningen (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 187572.48 €
Projet ORO (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Oxygen-containing molecules are widespread as medicines, agrochemicals, organic materials, perfumes and dyes. Their preparation could be greatly facilitated by implementing oxygen-radicals, which are a class of very versatile synthetic intermediates. However, to date, difficulties associated to their generation have severely limited their use and exploitation in synthetic settings. Here we propose the development of two conceptually novel and general ways to prepare oxygen-radicals using visible-light. These processes will capitalize on recent developments in the host group that has disclosed two novel organocatalytic ways for the generation of nitrogen-radicals. This proposal seeks to substantially expand this photochemical approach by developing unprecedented methods for the generation and use of oxygen-radical. The power of this approach will be demonstrated by fast generation of 3D molecules containing multiple atoms of oxygen. These methods will be then integrated with other reaction platforms that, taking advantage of visible-light as source of energy, will engage the oxygen-radical in new reactivity modes, to allow novel and powerful multicomponent oxo-functionalization reactions. Furthermore, we will harness this activation modes to enable the direct oxygenation of aromatic compounds in a single step without the use of transition metal catalysts. Through the use of this strategy, the rapid construction of many relevant and complex oxygenated molecules will be possible. The development of such an innovative and ambitious project at the University of Manchester will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance my career development following the training plan envisioned.

Mots clés : oxygen radicals, visible light, photoredox catalysis, single electron transfer, electron donor acceptor complexes, oxygen heterocycle

Participants :
- University of Manchester (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet PASTEURDOC (Horizon 2020, appel à projets 2014)
Action : Cofund Doctoral programme
Statut du projet : CLOSED

PASTEURDOC is an advanced educational and research program, hosted by the Institut Pasteur in Paris. Its goal is to train junior investigators possessing medical and/or scientific educational backgrounds to become future leaders in academic education and research institutions, international organizations, private companies, or administration. PASTEURDOC is intended to co-fund and advance the already well-established and very successful Pasteur Paris University International Doctoral Program, in operation since 2009 in partnership with three renowned Parisian universities. PASTEURDOC will enhance the host capacity to train young researchers, while strengthening the Marie Skłodowska-Curie Actions recommendations for professional development of early-stage researchers. The PASTEURDOC objectives are the following: 1) To provide the highest scientific education by proposing a large panoply of multidisciplinary research projects and scientific approaches. These will encompass an array of biomedical research fields crucial for human health, and lead to an internationally recognized Doctorate diploma. 2) To provide an exceptional nurturing environment combining practical research, scientific and transferrable skills training and educational follow up, by a well established Teaching Department running and International Doctoral Program. 3) To provide the early-stage researchers with a large international and multicultural network of fellows and institutions, in both developed and developing countries, and within the academic and the private sectors. 4) Two calls will be launched during the 60 months program, in order to train 30 early-stage researchers, recruited for 36 months. PASTEURDOC will significantly enhance the international visibility and the training capacity of the Pasteur International Doctoral program.

Mots clés : doctoral program, biomedical research, global health

Participants :
- Sorbonne Université (France) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Paris Cité (France) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut Pasteur (France) — Coordinator, beneficiary, Recherche, subvention : 2354400.0 €
Projet PATH (Horizon 2020, appel à projets 2016)
Action : Staff Exchanges
Panel : Physics
Statut du projet : CLOSED

PATH is intended to promote a collaborative researches focused in the development of high density plasma sources implemented with the Exchange of staff personnel between the partners of the network. The research will also address transfer of knowledge and training of the researchers in the specific field of plasma sources and its applications in the telecommunication sector. High density plasma sources find large number of industrial applications from material treatment to Telecommunication. Overcoming the density limit of current source will open new frontier in several technological field. PATH aims at cross linking different competences to study and develop prototype of plasma sources and plasma antenna based on hybrid technologies based on Radiofrequency and Hollow cathode technologies. A Gaseous Plasma Antenna (GPA) is a plasma discharge confined in a dielectric tube that uses partially or fully ionized gas to generate and receive electromagnetic waves; GPAs are virtually “transparent” above the plasma frequency and become “invisible” when turned off. Unlike ordinary metallic antennas, GPAs and Plasma Antenna Arrays can be reconfigured electrically (rather than mechanically) with respect to impedance, frequency, bandwidth and directivity on time scales the order of microseconds or milliseconds. It is also possible to stack arrays of GPAs designed to operate at different frequencies. A Plasma Antenna will be able to: (i) identifying the direction of incoming signal, (ii) tracking and locating the antenna beam on the mobile/target, (iii) beam-steering while minimizing interferences. Actual technology is based mainly on: (i) DC discharge, (ii) AC discharge, (iii) RF discharge, (iv) Microwaves, (v) Hollow cathode. Improvement of plasma source performances require a strong effort in term of modelling and technology. The aim of PATH is to merge European competences to make a substantial step toward innovative hybrid plasma sources.

Mots clés : plasma antenna, antenna design, antenna simulation

Participants :
- Alma sistemi srl (Italie) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 202500.0 €
- Technology for propulsion and innovation srl (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 27000.0 €
- Technical University of Crete (Grèce) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 148500.0 €
- Shanghai University (Chine) — Partner, organization partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University of Southampton (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 157500.0 €
- University of Padua (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 144000.0 €
- Mars Space (United Kingdom) (Royaume-Uni) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 112500.0 €
- Fieldscale pc (Grèce) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 0.0 €
Projet PAVax (Horizon 2020, appel à projets 2019)
Action : Doctoral Networks - Industrial Doctorates
Panel : Chemistry
Statut du projet : SIGNED

PAVax is a network that will train 4 early-stage researchers (ESRs) on the conception of new synthetic vaccines to combat the antibiotic resistant bacterium Pseudomionas aeruginosa (PA), for which there currently is no adequate vaccine available. This consortium will explore and exploit the use of PA-exopolysaccharides that play a key role in biofilm formation that protects the bacterium from its environment: alginate, Psl and Pel. We will exploit these saccharides to generate novel vaccines targeting these exposed polysaccharides. Next to the isolation of these polysaccharides from the bacteria, we will employ synthetic chemistry to deliver well-defined fragments of these polysaccharides. These will be used to map the interactions of the saccharides with antibodies to inform on the structure of the optimal epitope. We will conjugate the (synthetic) fragments to newly discovered PA proteins to generate conjugate vaccines targeting multiple PA entities. The consortium is formed by an academic partner, Leiden University (NL) and an industrial partner, GSK Vaccines, Siena (IT), harnessing the complementary expertise of both partners to achieve the ambitious goals set. The close collaboration between the two partners will ensure training of the ESRs at the highest level and best synergy possible. The ESRs will receive intersectorial, international and interdisciplinary training in (synthetic) carbohydrate chemistry, vaccine design, protein chemistry and conjugation, biophysical interaction studies, and immunology. With the ever-growing awareness of the importance of carbohydrates in health and disease, and the continuous threat of multidrug resistant bacteria, the skill set acquired by the ESRs will prepare them to face the major scientific and societal challenges ahead and become important players in academic or industrial research in the future

Mots clés : bacterial glycans, synthetic chemistry, conjugate vaccines, carbohydrates, structure elucidation, antibodies, pseudomonas aeruginosa, std nmr, carrier proteins

Participants :
- Leiden University (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 531239.76 €
- GlaxoSmithKline (Italy) (Italie) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 522999.36 €
Projet DRAPer (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Physical disabilities due to illness, injury, or ageing can alter the way a person moves around the house, manipulates objects and senses their home. These issues make it harder for persons to execute daily home activities on their own, and therefore specialized professionals are required to take care of them. However, the growing elderly population and the persons having basic activity difficulties or suffering from long-standing diseases are saturating the health systems due to insufficient infrastructures and over-demand for health carers. Robotics-based solutions are a promising alternative to support the human labour at health care. This project focuses on how robotic assistants can be exploited to provide independence and empower people with different kinds of mobility problems. Specifically, the main goal is to assist these persons in dressing themselves, which has been found to be an important task for independent living. In this sense, a robotic dressing assistant needs to skilfully manipulate clothes, physically interact with the human, recognize his/her intentions and actions, and easily adapt to changes in the clothing, user posture, and degree of mobility of the assisted person. These highly complex features are tackled in this proposal from a robot learning perspective, in which programming-by-demonstration, reinforcement and interactive learning will be combined to create both sophisticated manipulation skills and safe assistance behaviours. The proposal envisions three different real experimental scenarios to test the proposed approaches and show their performance with real (able-bodied) participants (with restricted motion). This project will not only advance the state of the art in assistive robotics, robot learning and human-safe control, but also will play a major role in helping persons with reduced mobility to live independently for longer and with a better quality of life.

Mots clés : robot learning, robotic assistant, programming by demonstration, human robot interaction, physical human robot interaction, reinforcement learning, interactive learning, deformable objects

Participants :
- Spanish National Research Council (Espagne) — Coordinator, beneficiary, Recherche, subvention : 170121.6 €
Projet SURFING (Horizon 2020, appel à projets 2019)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Physical phenomena that combine effects on a surface and that in the bulk occur in many fields, ranging from crystal growth in chemistry and proton diffusion in biomembranes, through tyre aquaplaning and self-cleaning materials. We consider this multi-scale problem specifically for coupled bulk-surface fluid flow. Simulating these problems with traditional fluid solvers is challenging because of the different scale of the surface phenomena versus that in the bulk. Towards this end, specialized thin film flow models have been developed to accurately capture surface-level flow effects. However, it remains impossible to automatically detect the formation of thin fluid sheets and resolve the bulk/sheet coupled flow. This limits the application of thin film models. Advances made in thin film modelling have not been applied to complex flow situations where, for example, a free flowing bulk fluid can form thin films over an obstacle, or where sufficient fluid collects on a moving thin fluid sheet to obtain bulk flow. Such problems rely on bulk flow simulations with significantly finer resolutions to capture the surface-level effects, which dramatically increases computation time making full dynamic simulations unrealistic for actual applications. The primary objective of this project is to model bulk/surface flow phenomena numerically. We will propose novel mathematical models to computationally simulate flow of thin fluid sheets on moving curved surfaces, which can predict not just the evolution of an existing film, but also their formation, collapse and break up. We will develop efficient methods to two-way couple film flow with bulk fluid flow which are able to identify regions where surface level effects are relevant, on the fly. This fellowship will build on the expertise in fluid flow and particle methods of the researcher, and that in multi scale modeling, free boundary problems and advanced discretisation adaptivity of the host.

Mots clés : thin films, fluids, multiscale, model adaptivity, particle methods, meshfree

Participants :
- University of Luxembourg (Luxembourg) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 178320.0 €