Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet 6G-ISLAC (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

In parallel to the evolution of 5G communication systems, 6G concepts are being developed in the academic community. In 6G, several key technical enablers are envisioned: i) mmWave and THz frequencies electromagnetic with extremely large bandwidths, and extremely large antenna arrays; ii) reconfigurable intelligent surfaces that control the propagation environment; and iii) machine learning to solve problems for which mathematical models are not sufficient. As location-aware communication (i.e., to optimize network efficiency and communication capacity by exploiting location, map, and trajectory information) is already a part of 5G, we expect that the 6G key enablers will also lead to high-accuracy sensing and localization and, in turn, improve communication quality. The goal of this project is to develop integrated sensing, localization, and communication systems for 6G, and the project comprises the following 3 work packages (WPs). In WP1, joint parameter estimation methods for the 6G channel are studied, and low-complexity methods will be developed based on the inherent high resolution of the 6G channel. By exploiting the estimated channel parameters of 6G signals, novel methods for estimating user state as well as sensing the time-varying propagation environment will be developed in WP2. We will design methods to use sensing and localization information from WP2 for initial beam search, beamspace processing, beam alignment, and power allocation in WP3. In doing so, we address several of the fundamental challenges in 6G communications and high-accuracy sensing and localization.

Mots clés : 6g, channel estimation, joint sensing and communications, multi target tracking, thz frequencies

Participants :
- École polytechnique Chalmers (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 222727.68 €
Projet SYSVAL (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

In the face of controversial debates about appropriate influence of values in the assent phase of science (where hypotheses/theories are accepted or rejected), which provide only complicated guidelines on a case-by-case basis, a confused image of science arises in the view of policy makers, the wider public, and even scientists. Such unsettled debate has a potential negative impact on the trust the general public puts in science. Worse, it can be used by science deniers to support their undermining enterprise. This is why progress on this issue is of paramount importance. A simple and systematic model for incorporating values in the assent phase of science, while at the same time preserving its integrity, is sorely needed. This is what this project aims to achieve. 1. The project will start with a systematic analysis of the philosophical debate about values in science, in order to make an inventory and classify the various positions according to criteria such as value-freedom or value-ladenness, kinds of value, types of influence, priority of some values over others, etc. 2. Among these, a selection, at the conceptual level, will be made of the best candidate for a simple, systematic and integrity-preserving value-laden model -- which is the main methodological assumption of this project. 3. This model will be criticized and optimized, at the conceptual level (for both theoretical and practical goals), by providing: possible adjustments, complementations, objections, or simplifications. 4. This model will be confronted to empirical case studies, to illustrate, expand or revise it. Three case studies will be performed by the researcher: in aeronautical engineering, climate science and interdisciplinary studies in the social sciences. 5. Finally, the conceptual and empirical findings will be synthesized to reach an optimized (simple, systematic and integrity-preserving) model.

Mots clés : epistemic and non epistemic values, acceptance rejection of scientific hypotheses, aeronautical engineering, climate science, sts, integrity of science, corpus model

Participants :
- Université d'Uppsala (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 222727.68 €
Projet Micro-magnetron (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : CLOSED

Famous scientist Freeman Dyson states that most of the scientific developments are tools and instruments driven. For instance, X-rays, as a scientific tool was discovered by Roentgen using Lenard's vacuum tube. Apart from the significant scientific breakthrough and discoveries, the technological advancement of tools is needed to serve the growing demands in communication, healthcare, security and manufacturing industries. Medical imaging applications from cancerous cells diagnostic to teeth caries, space applications from the universe exploration to upper atmosphere studies, homeland security applications to identify persons with concealed arms, and industrial applications such as non-destructive testing can be made possible with non-ionising, high bandwidth THz frequencies. Despite these advantages, A THZ gap exists between electronics and photonics. Compact electron devices are needed to exploit these potential advantages. With the collisionless propagation nature of an electron beam, the micro vacuum electron devices generate higher power per unit volume than solid-state devices and Lasers. From the victory of World War II to present daily services in our kitchen, magnetron tube has given unbeatable performance at many scientific and industrial fronts. With these motivations, we put this veteran magnetron tube on THz fronts in the current proposal. The THz micro-magnetron is proposed to serve medical imaging and RADAR applications for homeland security, earthquakes evacuation, material investigation. The EM wave power generation with a high degree of compactness will be turned into an innovative solution as listed: 1. With a non-ionising nature, the THz micro-magnetron based system is an economical alternative for medical imaging, including various cancer diagnostic 2. A portable standoff device for the detection of concealed arms at crowded places. 3. Highly suitable for restricted payload environments such as space-borne RADAR and UAV-enabled 3D imaging RADAR.

Mots clés : magnetron, microfabrication, medical imaging, radar, terahertz, vacuum electronics

Participants :
- Université d'Uppsala (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 206887.68 €
Projet CHINOS (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Chirality is an inherent property in nature characterized by asymmetry and distinctiveness. Incorporating chirality into semiconductors has provided unique optical and electronic characteristics that differ from those of achiral semiconductors, leading to innovative applications in optical communication and quantum computation. This project aims to comprehensively explore the synthesis of a emerging chiral semiconducting nanomaterial, chiral semiconducting nanoplatelet assemblies, and examine their potential in optoelectronic and spintronic devices. The project is separated to three primary objectives: 1. Develop synthesis methods for chiral nanoplatelet assemblies. 2) Investigate and enhance the chiroptical properties of these assemblies. 3) Integrate the chiral assemblies into photodetectors, LEDs, and spin polarizers. This research will contribute to the advancement of next-generation optical communication and quantum information technologies.

Mots clés : chirality, semiconductors, nanoplatelets, assembly

Participants :
- Italian Institute of Technology (Italie) — Coordinator, beneficiary, Recherche, subvention : 193643.28 €
Projet PACMUM (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

This interdisciplinary research project is situated on the crossroads of women’s health and media psychology. The supervisor and the fellow, will combine their expertise to study how exposure to pregnancy- and childbirth-related content on the popular social media platform YouTube can affect pregnancy-related anxiety (PRA). We know from the women’s health literature that pregnancy-related anxiety is a serious issue and many pregnant women seek health information online, and we know from the media psychology literature that seeking online health information can affect cognitions and behaviors, but these two fields of research remain disconnected. By bridging the two research fields, the scattered research will be systematized and extended. We set forth 2 objectives, each comprising three research questions: to improve our understanding of how pregnancy- and childbirth-related content on YouTube can fulfill different needs for women with PRA (objective 1), and to elucidate the underlying processes of the association between exposure to pregnancy- and childbirth-related content and PRA (objective 2). To reach our objectives, we will use a multimethodological approach, in which we combine semi-structured interviews (Work package 1, objective 1) and a longitudinal panel study following a cohort of women throughout their pregnancy (WP2, objective 2). The longitudinal panel study will be incorporated in the large scale mobile application-based Mom2B project currently running at the Uppsala University, which combines automatically collected digital phenotyping data, self-report questionnaires, and objective information from national health registers. This project will significantly improve our understanding of how social media can be strategically used by researchers and health workers to improve public health, but also of how peers and influencers on social media can informally and often unintentionally play a role in their followers’ health behaviors and experiences.

Mots clés : media effects media psychology women s mental health health communication

Participants :
- Université d'Uppsala (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 222727.68 €
Projet SPUREPER (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Lead halide perovskite nanocrystals exhibit high emission coefficients with controllable shapes, sizes and compositions. Moreover, the self-assembly of perovskite nanocrystals into consistent superlattices can generate a focused and intense burst of collective coupling emission called superfluorescence. These prominent features made them attractive in light-emitting and laser applications. In SPUREPER, shape-tuning perovskite nanocrystals will be synthesised via a new route and pure perovskite superlattices through different shapes of nanocrystals with controllable aggregated structures and enhanced collective emission will be explored. In WP1, a concept of post-injection of halide source and alkylamine ligands into the lead-oleate and caesium-oleate complexes is proposed to achieve monodisperse perovskite nanospheres and nanocubes. Introducing other metal cations partially replacing lead at the beginning of synthesis controls the growth of crystals, and post-injecting alkylamine modifies the nanocrystals into a spherical shape. In WP2, pure perovskite superlattices in various three-dimensional structures will be built by co-assembling perovskite nanospheres and nanocubes. The size and relative ratios of nanospheres and nanocubes will be tuned to modify nanocrystal packing structure, packing density, and aggregated orientations in superlattices. Moreover, the self-assembling behaviour of solely perovskite nanospheres will be exploited. In addition, the influence of the solvent, whose polarity and volatility are essential in forming a well-organised three-dimensional structure, on the arrangement behaviour of superlattices will be studied. In WP3, superfluorescence will be measured in these various perovskite superlattices. Peak shift and intensity adjustment of the coupling emission will be correlated to the packing manners involving structure, density, and coupling number in the superlattices.

Mots clés : perovskite nanocrystals, spherical shape, self assembly, superlattices, three dimensional structure, superfluorescence

Participants :
- Italian Institute of Technology (Italie) — Coordinator, beneficiary, Recherche, subvention : 172750.08 €
Projet ConPLED (Horizon 2020, appel à projets 2018)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

The development of low-cost, clean, and scalable energy solutions is imperative to securing a peaceful and sustainable future. Optoelectronic devices such as light-emitting diodes (LEDs) incorporating new, inexpensive materials show tremendous promise to alter the energy landscape by reducing the cost of energy consumption. However, the widespread adoption of LEDs demands new technologies to surpass the luminous efficacies of conventional LED light while having a full control over colour, brightness and directionality of the light source. Recently, a new class of semiconducting materials, ABX3 perovskites, is poised to revolutionise the LED field due to its ease of processing and outstanding electronic and optical properties. In this context, the ultimate goal of this proposal is the development of the first efficient white light LED based on luminescent nanostructured perovskites that feature tuneable on-demand emission properties. ConPLED will result in an alternative to commercial white LEDs, with the additional gain of having finely tuneable electroluminescence based on cost-effective materials processed at low temperature. The combination of perovskite nanocrystals that show quantum confinement effects with photonic nanostructures, an area where the researcher has demonstrated proficiency, will lead to fine control over the colour gamut, and the angular bandwidth of light emission. A deep understanding of the electro-optical and structural properties of such nanostructured emitting materials will lead to demonstrate efficient white light LEDs, which is one of the main activities of the Optoelectronics group at Cavendish Laboratory (University of Cambridge). The project covers the experimental realization of materials and their integration in devices as well as advanced characterization and performance tests, all of which lies in the common ground of physicists, chemists and technologists and, thus, will naturally broaden the area of expertise of the researcher.

Mots clés : perovskite, white light leds, nanocrystals, quantum confinement, optical materials

Participants :
- University of Cambridge (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 224933.76 €
Projet metaC-Hfunct (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The development of methods for the transition metal-catalysed functionalization of C-H bonds is revolutionizing synthetic organic chemistry by providing tools to simplify and accelerate the synthesis and modification of a myriad of known and still unknown organic molecules including aromatic compounds. However, in these processes, the ability to discriminate between C-H bonds for subsequent transformation into other functional groups still remains as a major challenge. To date, much progress has been made on developing strategies for the ortho-functionalization of arenes, mainly through the derivatization of the substrates with directing groups. meta-Functionalization approaches, on the other hand, are extremely scarce despite eta-substitution is a widespread motive amongst biologically active molecules. The research outlined in this proposal aims at developing a process that makes use of CO2 as an invisible directing group leading to an array of novel direct meta-functionalization methodologies. To do so, we envision a one-pot strategy involving a carboxylation ortho to an R group followed by a tandem CO2H directed ortho-functionalization/decarboxylation process that affords the desired meta-functionalized products and releases again the CO2 employed as the directing group. The realisation of the objectives of this project will push forward the state-of-the art in the area of C-H bond activation by providing step economical access to molecules that are difficult to prepare via conventional multistep routes.

Mots clés : c h activation, meta olefination, co2 fixation

Participants :
- University of Manchester (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 183454.8 €
Projet HI_IM_NEUROSOCIETY (Horizon 2020, appel à projets 2017)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

The development of neuroimaging techniques, such as computed axial tomography (CAT scanning), functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), has been one of the major biomedical achievements of the past hundred years. These techniques allow the in vivo visualisation of the brain and gave new impetus to medicine, neurology, psychiatry, psychology, philosophy, economics and related fields by providing two unprecedented types of insight. Nations worldwide are making unprecedented investments in neuroimaging-related research: key projects include the European Human Brain Project, which is a H2020 FET Flagship Project (started in 2013, $1.2 billion), the US BRAIN Initiative (2013, $1 billion) and the Japanese Brain/MINDS (2014, $310m). Neuroimaging breakthroughs are making history, but the history of neuroimaging needs to be comprehensively assessed and the impact of neuroimaging on our society still needs to be properly defined. These are the key aims of this MSC Action, which is aimed at developing the first interdisciplinary platform worldwide on the history and impact of neuroimaging. Investigating neuroimaging in a historical perspective will fundamentally contribute to an integrated understanding of how neuroimaging has been shaping and is shaping biomedicine, culture and society. A critical history of the ways in which we see and study the brain is also crucial to increase the awareness about past and current research with neuroimaging, to involve the general public in a constructive debate about neuroscientific and societal challenges, and to promote a scientific culture about neuroimaging techniques and their applications.

Mots clés : neuroimaging, neuroscience, history of neuroscience, history of neuroimaging, history of neurology, medical humanities

Participants :
- Istituti di Ricovero e Cura a Carattere Scientifico (Italie) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 168277.2 €
Projet SUGARSmart (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

The development of new approaches to explore the diverse role of glycans in normal and physio- pathological conditions of the cell is a major challenge. Our previous research recognized roles of anti-glycan recognition molecules (lectins and antibodies) in the diagnosis of diseases like cancer, immunity, and hyperacute rejection upon bioprosthetic transplantation etc. However, because of the structural complexity, well-established approaches for developing glycan-based therapeutics are limited. To address this issues, SUGARSmart aims to develop a workflow for rational design of single-chain fragment variable (scFv) antibodies to enhance glycan recognition capabilities, both specificity- and affinity-wise (improving detection limits of assays). Three major aims will be pursued: First, we will apply molecular modeling to predict mutations which lead to enhance affinity and specificity of anti-αGal scFv. A range of mutational strategies will be tested in order to learn which scFv domains, which particular locations (functionally important sites), and which mutations (aromatic or polar) are best suited to improve affinity and specificity. Second, computationally predicted mutants will be obtained by mutagenesis or chain shuffling. Validity of the predictions will be tested by affinity-measurement (ITC/SPR), array techniques and ELISA. At the end, validation of computational models of scFv-glycan interactions with experimental techniques will enable us to propose a workflow to engineer other anti-glycan scFv antibodies. Overall, this project proposes an interdisciplinary approach to enhance our ability to quantify and engineer glycan recognition molecules having potential application in the smart and tailored development of future diagnostic reagents and therapeutics. To the best of our knowledge this will be the first attempt to provide a complete and coherent framework for anti-glycan antibody engineering, combining a wide computational pipeline and experiments.

Mots clés : glycans, antibody, rational design, antibody engineering, carbohydrate recognition agent, scfv, modeling antibody glycan interactions

Participants :
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175866.0 €
Projet Amine-FUNC (Horizon 2020, appel à projets 2014)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

The development of new chemical transformations based on catalytic functionalization of unactivated C-H bonds has the potential to simplify the synthesis of complex molecules dramatically. Although some progress have been achieved in this emerging area, the selective transformation of aliphatic C-H bonds is still a challenge. This proposal aims to develop a new platform for the direct activation of unactivated sp3 C-H bonds of aliphatic amines and to apply this novel C(sp3)-H functionalization technology to synthesize diverse amine compounds. A key novel concept of this project is to use an unprotected aliphatic secondary amine as a native directing group, through a remarkable 4-membered-ring cyclometallation pathway. The goals of this proposal include: (I) developing unprecedented diverse C(sp3)-H functionalization of amine technology, accessing diverse functionalized amine compounds, (II) developing novel Pd-catalyzed enantioselective C-H functionalization methods to make enantioenriched chiral molecules, (III) application of this novel C(sp3)-H functionalization technology to make a library of diverse functionalized Salbutamol and Bupropion analogues, and screen them for biological and medicinal activities.

Mots clés : synthetic methods, diverse c sp3  h functionalization, aliphatic amine, four membered palladacycle, salbutamol and bupropion analogues

Participants :
- University of Cambridge (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €