Projet ACHILLES (Horizon Europe, appel à projets 2024)
Action : Doctoral Networks
Panel : Life Sciences
Statut du projet : SIGNED

ACHILLES is a Doctoral Network (DN) program designed to train the next generation of leaders in hemato-oncology, with a focus on the development of novel therapeutic solutions for hematological malignancies. The network brings together 14 institutions from 10 EU countries and one associated state, along with partners from the biotechnology and drug discovery sectors, including two European policy leaders in hematology, the European Hematology Association (EHA) and the European School of Hematology (ESH). Through this collaboration, ACHILLES will train 16 Doctoral Candidates (DCs) to develop essential skills in experimental hemato-oncology, including the design, development, and preclinical validation of innovative therapies. ACHILLES is structured around three key scientific objectives (SOs): (1) creating novel experimental models and analytical methods, (2) exploring the oncogenic mechanisms of hematologic malignancies, and (3) developing and validating new therapies, especially targeted treatments for leukemia and lymphoma. The program will integrate cutting-edge technologies such as AI, multi-omics, and computational modeling to push the boundaries of current research and therapy development. These innovations will be applied to generate better diagnostic tools, predict treatment responses, and optimize therapeutic strategies. With a patient-centered approach, ACHILLES aims to foster both academic and industrial collaboration, bridging gaps between scientific research and clinical application. This initiative aligns with the EU's Beating Cancer Plan, with a particular focus on improving survival rates and treatment accessibility, especially in Widening Countries. Through strong academic-industrial partnerships, ACHILLES will help create a sustainable impact on the field of hemato-oncology, advancing research, therapies, and ultimately the health outcomes of leukemia and lymphoma patients worldwide.

Mots clés : leukemia, lymphoma experimental therapeutics drug discovery immunotherapy hematologic malignancies

Participants :
- Université libre d'Amsterdam (Pays-Bas) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Scienseed sl (Espagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Fondation nationale de la recherche scientifique (Grèce) — Partner, beneficiary, Recherche, subvention : 269484.48 €
- Institute of Mathematics and Informatics (Bulgarie) — Partner, beneficiary, Recherche, subvention : 237580.92 €
- Institut Karolinska (Suède) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 324630.0 €
- Université complutense de Madrid (Espagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 282188.16 €
- Université de médecine et pharmacie Iuliu Hațieganu (Roumanie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 246242.52 €
- Université d'Attique occidentale (Grèce) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Sant Joan de Déu-Barcelona Children’s Hospital (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- École polytechnique fédérale de Zurich (Suisse) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Barcelone (Espagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Sonja noss (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Onechain immunotherapeutics s.l. (Espagne) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 282188.16 €
- Centro de Regulación Genómica (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- European Hematology Association (Pays-Bas) — Partner, associated partner, Autres, subvention : 0.0 €
- CERCA Institution (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Milan-Bicocca (Italie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 281755.08 €
- Université de Lund (Suède) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut de Recherche et d’Innovation en Santé de l’Université de Porto (Portugal) — Partner, beneficiary, Recherche, subvention : 279445.32 €
- Université Eberhard Karl de Tübingen (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 290272.32 €
- Fundación Josep Carreras Contra la Leucemia (Espagne) — Coordinator, beneficiary, Recherche, subvention : 564376.32 €
- Fundació internacional josep carreras (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Amsterdam University Medical Centers (Pays-Bas) — Partner, beneficiary, Recherche, subvention : 305285.76 €
- Université de Belgrade (Serbie) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 248841.0 €
- Pixelgen technologies ab (Suède) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Sprint Bioscience (Sweden) (Suède) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Lead biologics international ab (Suède) — Partner, beneficiary, Organismes privés (hors enseignement), subvention : 324630.0 €
- Université Paris Cité (France) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 314669.16 €
- Cobiomic bioscience sl (Espagne) — Partner, associated partner, Autres, subvention : 0.0 €
- Leadership sculptor gmbh (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- European school of haematology (France) — Partner, associated partner, Autres, subvention : 0.0 €
- Institut de Recherche et d’Innovation en Santé de l’Université de Porto (Portugal) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Saso kocevar (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €