Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet PlasmOSS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : TERMINATED

Photochemistry on solid surfaces is a promising candidate for overcoming the current limitations of on-surface synthesis (OSS), including the constraints of metallic substrates, poor spatiotemporal control, and demand for high temperatures. However, this nascent approach has evidenced to date relatively modest efficiencies compared to thermally induced reactions. Concomitantly, the field of plasmon-mediated chemical reactions (PMCRs) has experienced pronounced growth. PMCRs rely on the ability of plasmonic nanostructures to harness the advantages of milder visible light and efficiently transforming it into chemical energy. The rapid progress in PMCRs can be attributed to the development of novel methodologies for engineering the nano-optical properties of the localized surface plasmon resonance (LSPR). In this context, achieving precise atomic-level control over how reactants interact with plasmonic catalytic substrates holds the potential to drastically increase the chemoselectivity, efficacy and sustainability of reactions. The scientific objective of this proposal is to combine my expertise on scanning probe microscopy (SPM) and plasmonic nanocavities with the large experience of the host in OSS, targeting to direct PMCRs on surfaces at the atomic scale. Specifically, this proposal seeks to investigate three model photodimerization reactions, exploring the conditions under which the SPM-controlled optical hotspot -used for tip-enhanced Raman spectromicroscopy- can be transformed into a chemical hotspot with improved selectivity and efficiency. Furthermore, the goal is to elucidate the mechanisms governing tip-induced PMCRs, with the ultimate aim of controlling the fabrication of low-dimensional extended polymers with molecular precision using visible light. The synergistic integration of these innovative methodologies will decisively contribute to the successful realization of the project, remarkably enhancing my career trajectory and personal development.

Mots clés : scanning probe microscopy, tip enhanced raman scattering, plasmonics, on surface synthesis

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Coordinator, beneficiary, Recherche, subvention : 165312.96 €
Projet CORALS (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Innovations in all-optical technologies hold the key to unlocking the next generation of faster and more efficient data processing and computing systems. Novel material platforms that can be controlled and manipulated using light are necessary building blocks for such technologies. One such platform is strongly coupled systems, where light and matter states coherently couple to form hybrid light-matter quasiparticles called polaritons. Polaritonic systems have already shown great promise in designing high-speed all-optical data processing systems. Achieving strong coupling has also been proposed as a basis for quantum information processing protocols, especially in the ultrastrong coupling regime where the strength of light-matter coupling becomes comparable to the energy levels of the interacting states. An important challenge in strongly coupled systems is the short-lived nature of the polaritonic coherence (and its time domain signature, Rabi oscillations), especially at room temperature. As a result, harnessing this short-lived regime for real-life implementation remains unrealized. The goal of this project is to experimentally observe long-lived coherent Rabi oscillations in the ultrastrong coupling regime and to demonstrate a novel ultrafast data processing operation using the Rabi oscillations. To achieve this, I will use state-of-the art ultrafast spectroscopy techniques to unveil the femtosecond-scale Rabi oscillation dynamics of a molecular polaritonic system at room temperature and demonstrate an optical switch that is an order of magnitude faster than state-of-the-art polaritonic devices. These results will address the knowledge gap in polaritonics in the ultrastrong coupling regime and spur research into harnessing coherent polariton dynamics for ultrafast all-optical applications. The outcomes of the project are expected to pave the way for future fast and energy-efficient quantum and all-optical information processing technologies.

Mots clés : ultrastrong coupling, ultrafast multidimensional spectroscopy, all optical switching, polaritonics, rabi oscillations, quantum coherence

Participants :
- Université d'Umeå (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 252180.0 €
Projet MuInSE (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

The development and promotion of lightweight vehicles is a crucial part of the comprehensive strategy of the EU to address global warming. Over recent decades, layered composite structures and porous materials have been the most attractive acoustically high-performance lightweight structures for designing lightweight vehicles. However, the design of these structures remains challenging in the vibroacoustic field due to the lack of advanced inverse characterization methods to overcome the limitations of various realistic conditions. To this end, the proposed research will provide a robust, efficient, and accurate multi-level wave-based identification framework for cross-scale material characterization, real material modeling, and inverse design of new materials with tailored properties by coordinating cutting-edge research and integrating advanced multidisciplinary techniques. In terms of macro-scale characterization, a new wave-based identification technique will be proposed for the first to characterize wave propagation of structures with complex shapes, such as open-cell porous materials and curved structures, under realistic complex sampling conditions. In terms of micro-scale characterization and real material modeling, this work will deliver a novel wave-based model fitting method to overcome limitations of the strict assumption of materials properties and external conditions of existing model fitting methods, allowing us to identify dynamic elastic modulus of fluid-saturated porous materials and structural properties of each layer of layered composite structures. Moreover, this work will bring a low-cost new material inverse design chain that integrates characterization, modeling, design, testing, and verification, only requiring structure response as input. This research will be a key step for manufacturers in the early design stage of lightweight vehicles, making a significant contribution to achieving the climate goals of the EU Green Deal and Fit for 55.

Mots clés : inverse characterization of composite structures and porous materials, cross scale structural identification, wave propagation identification, real material modeling, inverse design of new materials

Participants :
- KTH Institut royal de technologie (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 206887.68 €
Projet engineereD to Clear (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Chronic lymphocytic leukemia is a common leukemia in adults characterized by an extremely immune suppressive microenvironment, which leads to the failure of otherwise effective immunotherapy regimens including dendritic cell (DC) based tumor vaccines. Recent attempts to understand immune suppression in CLL provided substantial evidence and identified that over-expression of amino acid catabolizing enzyme interleukin-4-induced 1 (IL4i1) in CLL and immune cells as key phenomenon in CLL mediated immune suppression. IL4i1 is secreted by DCs in the immune synapse and downregulates CD8+ T cell effector functions while presenting antigens, which perfectly explains failure of DC vaccines in CLL treatment. Addressing this, the important objectives of the present project are 1. To investigate the negative impacts of IL4i1 on DC functions, which are in particular relevance to DC vaccines and 2. To analyze the potential of IL4i1 deficient DCs in CLL vaccination. In this project I will first study ex vivo the DC and CD8+ T cell dysfunctions associated with DC secreted IL4i1 by assessing antigen presentation, immune synapse formation, CD8+ T cell activation and proliferation using both model antigen SIINFEKL and whole CLL cell antigens. Next, I will feed IL4i1 deficient DCs with whole CLL cell antigens and study using cutting-edge techniques their potential in eliciting anti-CLL immune responses in vivo using Eµ-TCL1 adaptively transferred CLL mouse model (TCL1AT). I obtained my PhD in 2021 and presently working as research associate at the department of Biochemistry and Molecular Biology, University of Szeged, Hungary. I propose this project for Marie Curie postdoctoral fellowship- European fellowships. This project will be carried out in the division of Molecular Genetics, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg, Germany under the supervision of Dr. Martina Seiffert.

Mots clés : chronic lymphocytic leukemia, immune suppression, il4i1, aryl hydrocarbon receptor ahr , dendritic cells, dc vaccines, anti tumoural immunity, cytotoxic t cells

Participants :
- Helmholtz-Gemeinschaft (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 189687.36 €
Projet InMyWaves (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Millions of tons of plastic waste have been found in our oceans over the past 10 years, posing ingestion hazards to marine organisms and our food chain. These plastics enter the ocean either as microplastics (< 5 mm in size) or larger plastics which slowly disintegrate into smaller particles before sinking to the ocean bed due to polymer disintegration and biofouling. While past studies primarily focused on floating debris, the settling dynamics of microplastics below waves, which are turbulent in nature, are not well known. Although models exist and this problem has been looked at, due to the challenges in simulating finite-size particles, point-particle assumptions are generally applied in the analytical and numerical modeling of particle-laden flow. This neglects the effects of particle inertia. Moreover, the combined influence of waves and turbulence on particles of various shapes and sizes has never been coupled. This is a major deficiency in the state-of-the-art. Hence, in this work, I will focus on particle inertia, free stream turbulence, and the combined effects of waves, to pinpoint the key parameters that govern the particle motion in wavy turbulent flows. To represent the microplastics, various modeled particles will be fabricated and tested first in a quiescent flow. These particles will then be released into the large-scale water channel facility at NTNU subjected to free stream turbulence and waves. Two series of experiments will be conducted using advanced flow and wave imaging techniques to track the particle, turbulence, and wave motions simultaneously. The results of this work will lead to improved models for simulating the transport of plastic waste and pollutants in rivers and oceanic flows by incorporating the dominant parameters that have previously been neglected. It will also bridge the understanding between both oceanic and turbulence communities on the transport of microplastics.

Mots clés : particle laden flow, free stream turbulence, waves, particle inertia, particle turbulence interactions, particle turbulence wave interactions

Participants :
- Université norvégienne de sciences et de technologie (Norvège) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 224991.04 €
Projet MaDRAS (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Nuclear fusion reactors require materials capable of enduring extreme radiation levels, posing a significant challenge in materials science. Radiaton-induced defects such as vacancies, interstitials, and dislocations critically influence the mechanical and thermal properties of these materials, and their behavior is strongly affected by the material’s magnetic state. Understanding the interplay between magnetism and defect properties is essential for advancing nuclear material development and designing materials with superior mechanical and radiation performance. Spin-Lattice Dynamics (SLD) simulations, which couple atomic and magnetic degrees of freedom, provide an optimal framework and a powerful tool to explore these interactions at the atomistic level. The MaDRAS project aims to investigate the interconnections between defects and magnetic properties in nuclear materials through SLD simulations. By focusing on the role of magnetism in defect behavior in two candidate materials for fusion reactor, FeCr alloys and FeCrNiMn high entropy alloys, the project seeks to identify mechanisms that contribute to the development of materials with better performance for nuclear applications. The primary goals are to establish a computational framework for assessing both the role of magnetic excitations in radiation-induced defects in nuclear materials and the influence of such defects on magnetic properties. The successful completion of this project will not only contribute to the fundamental understanding of magnetism’s role in defect production and mobility but could also drive significant innovations in the design of materials for fusion reactors and other advanced nuclear technologies.

Mots clés : material science nuclear materials radiation damage defects magnetism spin lattice dynamics simulations

Participants :
- Université d'Alicante (Espagne) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 209914.56 €
Projet MEMANZ (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

MEMANZ investigates the construction of the memory of the battle of Manzikert in different literary discourses of the Medieval Mediterranean. The battle took place in the eleventh century between the sultan Alp Arslan of the Great Seljuks and emperor Romanos Diogenes of Byzantium. The capture of Romanos and the Byzantine defeat, the battle precipitated a chain of events that led to the civil war in Byzantium, a Turkic migration to Anatolia and the First Crusade.  MEMANZ uses notions of “triumph”, “trauma” and “loss” to demonstrate how educated literati from Eastern Roman, Latin, Seljuk-Arabic and Armenian linguistic spheres constructed the memory of the battle for their own aims and means. A Byzantine princess Anna Komnene used Manzikert to rally Byzantine nobles around the flag of her family. A Crusader bishop William of Tyre used it to justify the onset of the Crusades. A Seljuk-Arabic intellectual Ibn al-Athir used the battle to highlight the agenda of his Ayyubid rulers. Finally, a set of three Armenian historians depicted the battle as a meaningful event in the history of the Armenian community.  The project reveals many unknown connections between different narratives about the battle. It demonstrates how a single event produced several cycles of interpretations in four different cultures, and how the later generations of educated people re-shaped the memory for their audiences. MEMANZ demonstrates the multipolarity of collective memory in the Medieval Mediterranean that is not limited to the dichotomy of “East” and “West”. The analysis of the construction of the battle allows better understanding of the nature of ideological dichotomies in the European Mediterranean. It opens a new path for the analysis of ongoing confrontations, some of which still deploy memories of Manzikert in everyday discourse. In collective memory of several groups the battle remains a traumatic event and the understanding of it is important for the future of EU and it’s neighbors

Mots clés : byzantium, great seljuks, crusades, armenia, manzikert

Participants :
- Université de St Andrews (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 260347.92 €
Projet STRENGTH (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

Recent major earthquakes (e.g., Turkey (2023), Morocco (2023), Iran (2022)) have highlighted the vulnerability of substandard buildings resulting from poor design and construction practices. Although Fibre Reinforced Polymers (FRPs) are effective for structural strengthening, their high cost, fire protection requirements, and potential health and environmental risks limit their widespread use, particularly in developing countries. This underscores the urgent need for more sustainable, durable, and cost-effective retrofitting solutions and improved design regulations for practical application. STRENGTH addresses these challenges by developing an innovative, low-carbon retrofitting system using a novel mortar-based composite called GTRGM. This composite integrates AR-glass textiles within a geopolymer matrix, providing a fire-resistant and sustainable solution that is approximately 40% more cost-effective and has up to 8 times lower CO2 emissions and environmental impact compared to traditional FRPs. The GTRGM system is designed for flexural, axial, and shear strengthening of reinforced concrete beam and column members. The project builds on state-of-the-art retrofitting techniques, enhancing them with eco-friendly materials and industrial by-products to achieve optimal mechanical properties. Through a systematic, multi-scale experimental and analytical approach, STRENGTH aims to develop an innovative retrofitting solution with tailored functionalities to meet a wide range of performance requirements for substandard structures. The outcomes of the project will contribute to safer, more resilient structures and reinforce Europe's leadership and competitiveness in the retrofitting sector. By addressing existing knowledge gaps, the project will generate fundamental insights, develop advanced design models, and establish performance-based guidelines to promote the adoption of this innovative strengthening technique, resulting in significant economic and societal benefits.

Mots clés : retrofitting, strengthening, earthquake engineering, composite material, concrete, textile, sustainability, low carbon mortar, structural building elements, substandard rc structures

Participants :
- Université de Sheffield (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 260347.92 €
Projet DESY-HAT (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

A pressing challenge in synthetic chemistry is developing sustainable methods to convert abundant feedstocks into valuable chiral products. The DESY-HAT project addresses this by pioneering new catalytic techniques, powered by visible light, to achieve stereoselective functionalization of carbon–hydrogen (C–H) bonds, the most ubiquitous moiety in organic molecules. Specifically, the project aims to access complex chiral molecules directly from readily available C–H substrates, including natural products, through enantioselective C–H functionalization via Hydrogen Atom Transfer (HAT) processes. The DESY-HAT project focuses on using HAT to selectively target C(sp³)–H bonds in symmetrical and meso substrates. The resulting desymmetrization processes will provide direct access to highly enantioenriched chiral products. This innovative approach, combining HAT with enantioselective organocatalysis, is a largely unexplored frontier in the field. The project will develop HAT desymmetrization strategies and apply them for enantioselective C(sp³)–C(sp³) and C(sp³)–heteroatom bond formation.  The project benefits from the Melchiorre group’s expertise in radical photochemistry and organocatalysis and will receive industrial guidance from Bayer AG Pharmaceuticals to identify suitable C–H substrates and assist with scaling up processes to practical applications. Through this interdisciplinary research, DESY-HAT will generate chiral compounds with biologically relevant frameworks, advancing the field of asymmetric synthesis while providing me with crucial skills for the next stage of my career.

Mots clés : radicals, asymmetric catalysis, organocatalysis, hydrogen atom transfer, photocatalysis, desymmetrization

Participants :
- Université de Bologne (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 193643.28 €
Projet MetRa (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

In the period around 750 CE, a fleet of Viking war ships set sail across the Baltic. They were ambushed and part of the war party was slain. Their remains have been found in the form of two ship burials with 40 male warriors, buried on the Island of Saaremaa in modern day Estonia. Four of them, we now know to be brothers. Dubbed the ’First Vikings’, the fallen warriors and their ships represent the first Viking Raid. The time capsule of 40 warriors accompanied by a wealth of war gear in the form of weaponry and decorative adournments, represents a unique and unparalleled opportunity for material culture studies in medieval archaeology. MetRa is a pioneering research project aimed at equipping early researcher Ragnar Saage with the advanced analytical skills necessary to investigate and establish the origins of both the iron weapons and the copper-alloy decorative elements of the war band. This will be achieved using state of the art metal provenancing methods in archaeological science. The material investigation aims to complement results from previous research on the burial from strontium isotopes and aDNA analysis. The project will not only shed light on organisation and in-group identity of a single war band (i.e. issued war gear vs individual armament), but it presents an unprecedented opportunity to examine and interrogate material culture armaments across a single family, four brothers in arms and their relative. Can commonalities and/or differences in weapon and decoration origins nuance our understanding of the make-up of the Viking war band? Do the four brothers and their relative share weapons from the same smith? Or do their war goods paint a more complex picture of mobility of Norse warriors and their attainment of weapons and adournments in a martial society? The results may reshape our understanding of the earliest Viking raids, as well as improve our understanding on the logistics and organisation of such an event.

Mots clés : metal provenance viking age ferrous metallurgy la icp ms mc icp ms slag inclusion analysis lead isotope analysis warfare weaponry artefact biographies scandinavian baltic sea

Participants :
- Université d'Aarhus (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 230774.4 €