Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet SOCIAL (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : SIGNED

In 2022, 63% of the world population actively used social media, spending a daily average of 2 hours and 27 minutes on these platforms. Despite its widespread adoption, our understanding of social media's impact on health and well-being remains limited, mostly due to lack of data availability on social media use. SOCIAL leverages several unique data sets and takes a comprehensive approach to investigate the effects and susceptibilities associated with social media use. This knowledge is fundamental to design smart and effective regulations that promote promote individual well-being in an era of rapid digital evolution. This proposal introduces a novel perspective to social media research. It aims to study the 2021 Facebook papers leak, the 2022 TikTok ban on government devices, Instagram's transition to an algorithmic feed in 2016, and the 2024 EU Digital Services Act, examining their impact on social media users. Additionally, it investigates the genetic factors influencing social media usage patterns, utilizing molecular genetic data and a within-family design to explore whether genetic susceptibilities to mental disorders contribute to social media use patterns. This action, unfolding at Nova SBE in Portugal under Prof. Pedro Pita Barros' guidance and Cátia Batista collaboration, addresses research questions, offers training and career development, and greatly enhances skills and fosters my career prospects. By joining Nova SBE, I'll broaden my network, fortify capabilities, and leverage my expertise in health economics, econometrics, and social-science genetics to expand their research capacity.

Mots clés : health economics social media mental health genetic susceptibilities social science gentics impact evaluation natural experiments

Participants :
- Université nouvelle de Lisbonne (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 156778.56 €
Projet RIVALMENA (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

RIVALMENA proposes new research exploring the impact of interstate rivalries on the negotiation of political change after the fall of dictators in three countries across the Middle East and North Africa (MENA) region: Tunisia, Libya and Egypt,. Analysing the influence rivalries have on political transitions in the MENA is timely and important for understanding regional politics. The region is experiencing an unprecedented fall of long-serving authoritarian rulers, most of whom were ousted by national revolts. Yet, democratization rarely follows the fall of dictators and countries rapidly descend into civil wars or return to some form of authoritarian rule. RIVALMENA aims at showing the crucial role that interstate rivalries play in thwarting processes of political change toward democracy, thereby refining the dominant scholarly interpretation that points almost exclusively to national factors to understand the shortage of successful democratization processes in the MENA region. To attain the research objectives, RIVALMENA relies on a mixed methodological approach, including triangulation between qualitative and quantitative data. In addition to contribute to the advancement of academic knowledge, research outputs include the creation of databases and maps that will be useful to EU institutions for implementing its common foreign and security policy. The author has already conducted extensive research on the international relations of the MENA (both in the field and remotely) and can rely on a wide network of contacts that will facilitate the accomplishment of the research objectives and tasks.

Mots clés : interstate rivalries foreign influence democratization authoritarianism middle east and north africa mena

Participants :
- State of Maryland (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Ca' Foscari de Venise (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 288859.2 €
Projet TAMBO-AD (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Alzheimer's disease (AD) is the major cause of dementia. The disease has an escalating impact on public health due to an increasing prevalence among the aging population in Europe and globally. In light of the first disease-modifying therapies becoming available, early diagnosis and precise disease staging are crucial for timely implementation of the treatment strategy. In TAMBO-AD, I will build on my preliminary findings to leverage AD biomarker potential of tau simultaneously phosphorylated at two distinct sites. By combining my expertise in immunoassay development with the top technology available at the host institution, I will develop three novel Single Molecule Array (Simoa®) assays targeting p-tau217&231, p-tau205&217, and p-tau205&231. Through cerebrospinal fluid and plasma measurements in the Amsterdam Dementia Cohort, I will evaluate performance of all three p-tau forms as: 1) early diagnostic and 2) disease-staging biomarkers. For the best-performing plasma biomarkers, I will translate Simoa® assays into innovative fiber optic nanogold-linked immunosorbent assay format (FONLISA), which enables point-of-care testing. New point-of-care testing assays will maximize biomarker testing accessibility, enabling use in primary care centers and in remote or resource-limited areas. Finally, I will communicate the project and disseminate results in English and Polish during an intersectoral secondment at the patient organization — Alzheimer Europe. The TAMBO-AD project represents a pivotal opportunity to advance my research, grow professional network, and gradually become an independent researcher.

Mots clés : alzheimer s disease biomarkers body fluid blood immunoassay clinical neurochemistry assay development phosphorylated tau

Participants :
- Amsterdam University Medical Centers (Pays-Bas) — Coordinator, beneficiary, Recherche, subvention : 217076.16 €
- Alzheimer Europe (Luxembourg) — Partner, associated partner, Recherche, subvention : 0.0 €
Projet CLASSIC (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : SIGNED

CLASSIC (CLimAte riSk implicationS for fInance and the real eConomy) intends to contribute to understanding how physical and transition climate risk impact the financial system and the real economy by quantifying the linkages and feedback between the two.  There is consolidated evidence on the significant impacts of climate change on the real side of the economic systems. However, a much narrower, even though expanding, research has been done on the financial implications of climate risk. Identifying the source, transmission channels, direction and magnitude of these impacts is of primary importance to policymakers, the business and finance community for a decision-making robust to climate risk effects on the global capital markets.  CLASSIC contributes to understanding how physical and transition climate risks impact the financial system and the real economy by quantifying the linkages and feedback between the two. The project investigates the economic and financial impacts of physical climate risk and of transition risk posed by climate change mitigation policies in the context of the EU Green Deal and the EU fit for 55 policies. Methodologically, an integrated modeling framework is built by coupling the macroeconomic representation of the real side of the economy with the financial side. The multi-sector multi-country Computable General Equilibrium model ICES (Intertemporal Computable Equilibrium System) model describes the former, while a climate financial risk module represents the latter.  The applicant works with highly skilled, leading partners who join forces to achieve the strategic objectives of CLASSIC. The partners’ scientific excellence with their long teaming traditions provides a first-class environment for training and research. The ambitious plan for generation of impact and dissemination of outcomes paves the way to creating policies for effective targeting of climate risk and enables the creation of a new service for climate risk hedging.

Mots clés : climate risk, physical climate risk, transition climate risk, cge modeling, financial system modeling, climate finance, climate finance modeling, net zero transition

Participants :
- Université des sciences économiques de Vienne (Autriche) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 199440.96 €
- Université Ca' Foscari de Venise (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet DIGIMYTH (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

DIGIMYTH is an interdisciplinary project that adopts the tools of digital humanities (DH) in Arabic literary studies. It plans to create an open access digital archive through which it investigates the dynamics of the reception of Greek myths in Arabic literature produced in Egypt and in the Mashreq in the period 1850-1950. Thanks to its intersectional approach that involves DH, literary studies, historical and religious studies, the project aims at having an impact both on Arabic literary studies and on other fields of research. The general objectives of DIGIMYTH are to investigate how and when Greek myths were introduced into modern Arabic literature and to evaluate their impact on its development. The project envisages two primary specific objectives that address two main questions: 1) What are the modern Arabic literary texts containing references to Greek myths? The project plans to digitize relevant texts of Arabic literature that contain such references, and create an open access digital archive. This entails the application of IT tools to Arabic literary studies, which has made little use of digital research so far. 2) What are the dynamics of the reception of Greek myths in modern Arabic literature? While there are studies on the use of myth in Arabic poetry after 1948, they fail to determine the specific function of Greek myths, and to explain how these myths were integrated into the Arabic literary system before 1948. Resting on the data collected in the archive and on an interdisciplinary methodology that involves literary, historical and religious studies, DIGIMYTH aspires to answer the following questions: when and which Greek myths were introduced in Arabic literature? Is there any relation between the place and the reception of a myth, and between the latter and politics and ideology? How did the meaning of the myth change over time and space?

Mots clés : modern arabic literature, greek mythology, translation, transmission, egypt, syria, lebanon, palestine, 1800, 1900, reception studies, world literature, digital humanities, digital archive

Participants :
- Université de Rome « La Sapienza » (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 282046.08 €
- Université américaine de Beyrouth (Liban) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université Ca' Foscari de Venise (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet SAMEorNOT (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Human societies are sustained by flowering plants in different ways but especially as a key food supplier. However, it is known that increasing global temperatures strongly affect plant reproduction and the growing human population will require more food in short-middle term. Thus, to create new crop varieties more resistant to heat stress and with enhanced yield, a deeper understanding of the mechanism of plant sexual reproduction will be crucial for increasing the efficiency of plant breeding programs. Plant reproduction relies on a double fertilization process, in which two sperm cells from a pollen grain reach the ovule and one fertilize the egg cell while the other the central cell. In some species with dimorphic sperm cells a preferential fertilization of each sperm cell has been described, but for Arabidopsis thaliana as well as for many economically important crops with isomorphic sperm cells this question remains unclear. The main goal of this project is to identify by single cell RNA-seq analysis potential transcriptomic differences between the two Arabidopsis sperm cells. To do that, individual sperm cells from pollen tubes growing through female stylar transmitting tissue (semi in vivo) will be isolated by micromanipulation using a specially designed microfluidic chamber on an inverted microscope. The identification of differentially expressed genes would enable for the first time the creation of a sperm single-cell marker line to eventually explore a hypothetical preferential fertilization in Arabidopsis. These results can be adapted for plant breeding programs to develop impactful biotechnological tools, like haploid inducer lines with genetically modified sperm cells to specifically deliver components in the egg cell to induce in vivo gynogenesis. Additionally, the results will be a valuable scientific resource to address other topics beyond the preferential fertilization, like exploring hybridization barriers based on gamete recognition.

Mots clés : plant reproduction, pollen, sperm cells

Participants :
- Université nouvelle de Lisbonne (Portugal) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 137181.24 €
Projet MATES (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Bacteria, like animals, rely on transmission to spread and colonise new environments. In this context, the microbial communities that inhabit and/or transiently interact with animal hosts, collectively known as the “microbiome”, are key to animal health and fitness. The assembly of the microbiome in the hosts begins at birth and later undergoes a variety of dynamic processes influencing its establishment, function and evolution. Newly, research has theoretically recognized the importance of the microbiome associated with reproductive organs and fluids in influencing a range of reproductive processes and outcomes in males and females. The study of such communities founding the "reproductive microbiome" and the ease with which they could be tracked between hosts’ reproductive systems therefore offers key advantages for measuring the role of host-mediated transmission in microbiome assembly and variation. Still, we lack an understanding of the ecological mechanisms influencing such variation. Advances in meta ’omics are sparking interest in how microbiomes impacts physiology, propensity to disease and in turn natural and sexual selection. In addition, gnotobiotic organisms provide unique opportunities to study host-microbiota interplay with a level of experimental control that is not achievable in human studies. Coupling these two approaches should allow to pinpoint key mechanisms underlying this mutualistic relationship in a research field that is still in its infancy. In this light, we will make use of accurate observational systems that have been established to monitor interactions and mating events in the internally fertilising fish Poecilia reticulata, to measure the contribution of host contact to reproductive microbiome transmission and assembly, and how how this in turn shapes host-microbiome feedback effects on their mutual fitness. Here, we propose a research project that will fully address these challenges, providing a shift in host-microbiome research.

Mots clés : sexual selection, reproductive behaviour, host microbe interactions

Participants :
- Université Christian Albrecht de Kiel (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Padoue (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 209483.28 €
Projet URBANWASTE (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

This 2-year project combines innovation in urban theory with comparative research on two cities to advance knowledge on how circular economy and urban waste policy can be made more effective and just. Increasing municipal solid waste is leading to mounting environmental and social risks, especially in urban areas. Local governments are urgently trying to reduce waste generation, notably through the model of the circular economy. Yet, so far, policies have failed to achieve sustainable change in urban economies because the circular economy overlooks the multiple entanglements of waste within urbanites’ everyday lives and its embeddedness in the uneven global economy. In short, the decidedly urban nature of waste is neglected in circular economy initiatives. URBANWASTE will therefore see waste like a city, to demonstrate how waste is generated, handled and potentially reduced in the multiple processes and places of urban collective life as they interconnect with supralocal political-economic processes. Through an original blend of qualitative methods and approaches in urban political theory, urban political ecology and urban political economy, it will conduct studies of waste in Glasgow and Mexico City and place these in a global-comparativist frame. The project will build on the researcher’s research expertise and language skills to advance her theoretical and methodological skills in new empirical contexts. This will contribute to her ambition of becoming an expert in urban and sustainability studies. She will benefit greatly from two leading urban scholars: the main supervisor, Dr Beveridge, who will host her at the University of Glasgow, and the secondment supervisor, Dr Boudreau, who will support a 5-months secondment at the National Autonomous University of Mexico during the fieldwork in Mexico City. The project will produce novel insights in theory and practice to advance debates on circular urban waste policy in Europe and globally.

Mots clés : urban politics, urban waste, urban political ecology, global urban comparativism, circular economy

Participants :
- Université nationale autonome du Mexique (Mexique) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Glasgow (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 260347.92 €
Projet MASQUES (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : SIGNED

Video games are one of the most popular cultural media nowadays. Their narratives frequently feature rogues suffering the consequences of social determinism, one of the main characteristics of Picaresque Fiction. Social determinism involves circumstances such as social oppression or ethnic/gender discrimination. Due to this, certain contemporary and past worldviews, as well as current social challenges permeate Picaresque texts, allowing players to experience complex sociocultural contexts through rogues and fictional stories. Built upon my previous research that demonstrates the existence of a videoludic Picaresque that continues the legacy of Picaresque Literature, this project offers increased understanding of this type of contemporary Picaresque fiction insisting in the expression of the current social challenges that imbue it. The primary goal is to show how social determinism is embedded in these video games while manifesting worldviews aligned with contemporary social challenges and influenced by previous Picaresque Literature. Considering narrative and ludic aspects of this cultural medium, a model of analysis for the social determinism in video games will be developed using a multidisciplinary theoretical framework with the intention of exporting it to different media and genres. Despite not existing previous work that study social determinism in the videoludic Picaresque, there are authors who have explored this characteristic in Picaresque Literature, the worldviews of this type of fiction, or manifestations of oppression and discrimination in video games. This project will combine these theories, create new ones, and apply them to video games using a new model shaped with the blended multidisciplinary support of three renowned centres of humanistic knowledge of the University of Glasgow: the Centre for Comparative Literature and Translation, the Stirling Maxwell Centre of Text/Image Cultures and the Games and Gaming Lab.

Mots clés : picaresque literature, comparative literature, video games, text and image, history of ideas, transmedia studies

Participants :
- Université de Glasgow (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 260347.92 €
Projet DAFNE (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

RNA interference is a potent technology largely employed to trigger gene silencing and control specific biological processes. The delivery of small RNA is one of the most intriguing challenges in RNAi technology. Smart nanomaterials for safe and effective RNA delivery have been successfully exploited in animals, while a limited number of applications have been proposed in plants so far. The present project aims to develop and to validate smart hydrogel for small RNA (siRNA and miRNA) delivery able to knock down the expression of selected genes and ultimately promote osmotic stress tolerance in plants. To achieve these objectives, natural hydrogels such as dextran, poly(ethylene glycol), chitosan and alginate will be synthesised and functionalised with small RNAs in order to obtain nanomaterials with unique properties. Hydrogels will be applied to plant leaves and roots, both in vitro and in vivo. As proof of concept, DAFNE will target control genes such as phytoene desaturase (PDS) and green fluorescent protein (GFP) in the model species Arabidopis thaliana, whose knockdown phenotypes are well-known and easily detected. Subsequently, functional hydrogels will deliver stress-related miRNAs in order to develop drought tolerant plants in A. thaliana and in a representative food crop Solanum tuberosum. Merging distinct expertise, DAFNE will offer the candidate researcher multidisciplinary training in the field of plant biology and genetics, as well as in molecular and cell biology, which will expand her skills, currently based on chemical engineering.

Mots clés : rnai, plant genetics, climate changes

Participants :
- Conseil supérieur de la recherche scientifique (Espagne) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université de Salerne (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 188590.08 €