Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet TAKEBACK (Horizon Europe, appel à projets 2021)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

This project is an anthropological study of emerging forms of collective care at a moment where the interlocking crises of capitalism, democracy, and the environment have become more apparent than ever before. In the Global North, there is an increasing sense of urgency to enhance cities' sustainability. Yet, top-down paradigms of urban regeneration can contribute creating enclaves of environmental privilege, thereby excluding lower income and minority groups from their benefits. Much recent scholarly debate has focused on the multiple effects of evictions and displacements, as well as on active practices of resistance. But what happens if, after years of protests, grassroots groups become the main actors in processes of collective re-appropriation and management of urban spaces?  TAKEBACK is based on an ethnographic study of collective reappropriations of vacant ex-industrial buildings, retrieved from top-down reconversion by activists and local residents in Montreal, Canada. By going beyond a view of social movements as bounded and organised entities, it explores the understudied topic of the “afterlives of a movement”, namely what happens when a heterogeneous political collective reaches some of its goals and, thus, changes shape, ambitions, and setting. It examines evolving trajectories and practices of collective care within activism, in order to contribute to debates on the shifting meanings of urban citizenship in an increasingly vulnerable world. TAKEBACK will allow me to gain new knowledge in the areas of urban geography and visual ethnography, to combine this with my previous expertise in political anthropology and ethnographic research, and to further my career prospects with a book monograph as major output of the fellowship. The project also speaks directly to EU missions directed at supporting the European Green Deal and Just Transition Mechanism.

Mots clés : urban activism citizenship solidarity environmental gentrification montreal

Participants :
- Université Concordia (Canada) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- École polytechnique de Turin (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 187248.96 €
Projet FLUO.OPC (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Generating a complex optical excitation pattern through biological tissue is of great importance for non-invasive biomedical studies. However, for many biological applications, our ability to control light is greatly limited by multiple scattering and physiological motions. While optical phase conjugation has potential to overcome these challenges, techniques based on fluorescence are still at an immature stage, requiring a single isolated guide star. Exploiting multiple or extended fluorescent guide stars will greatly benefit a wide range of applications, such as deep tissue optogenetics, because of the availability and targeted labeling of fluorescent probes. The goal of this proposal is to achieve active control of light through scattering media using multiple or extended fluorescent guide stars via advanced holographic technique and optical phase conjugation, and test its viability for biological tissue.

Mots clés : multiple scattering, wavefront shaping, holography, optical microscopy

Participants :
- Sorbonne Université (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195914.88 €
Projet SPEEDBUMPS (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : SIGNED

Quantum information represents a paradigm-shift in the way we exchange information, with the EU and the US investing substantial economic resources on basic research and technological developments. Propelled by these efforts, the research community intensely worked on physical sources of quantum bits, qubits, the quantum information basic units. In particular, Single Photon Sources (SPS) offer the perspective of modular quantum information circuitry elements. In this framework, transition from fundamental research to technology is a necessary step towards their use in a broader and application-oriented use. SPEEDBUMPS will develop plasmonic-enhanced tapered optical nanofibers (ONF), a highly reliable SPS generation and collection system exploiting on-waveguide localized plasmon surface resonances to generate periodic flows of single photons on a ready-for-integration waveguide with enhanced optical properties. To do this it will pursue three main objectives to surpass the current state-of-art of fiber-based SPS: 1. Exploiting SPS typically requires bulky optical setups, limiting the translation in applicative frameworks where no strong expertise in optical systems is required. SPEEDBUMPS will demonstrate the integration of SPS with other optical systems, coupling them with the strong evanescent field confined at the surface of a ONF. 2. SPS-ONF coupling alone fails at obtaining collection efficiencies higher than the 10% of the photons emitted by the SPS. To increase the system efficiency SPEEDBUMPS will realize an optical cavity deterministically fabricated on the ONF with unconventional nanofabrication approaches. 3. To further increase the efficiency, in SPEEDBUMPS the isotropic radiation field will be modified through complex nanostructuring of the ONF to realize field-redirecting elements. Due to the ONF’s nature (suspended, dielectric, curved, nanometric) these results will be unprecedented, paving the way to novel applications in the field of quantum optics.


Participants :
- Italian Institute of Technology (Italie) — Partner, associated partner, Recherche, subvention : 0.0 €
- Sorbonne Université (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195914.88 €
Projet GENIUS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

In the midst of the automation revolution, the GENIUS project confronts a critical challenge, ensuring the seamless transition from autonomous to manual control, referred to as driver take-over control (TOC), within conditionally automated vehicles (CAD). As automation reshapes the transportation landscape, prioritizing safety during TOC is paramount. GENIUS introduces an innovative, real-time, multimodal interaction system tailored to optimize both the time and quality of TOC, leveraging biometric sensors to gauge driver readiness, awareness, and physiological status. This adaptable system dynamically adjusts TOC using interaction modalities while tailoring the experience to the unique characteristics of individual drivers. Beyond its immediate applications, GENIUS holds the potential to enhance TOC in higher levels of vehicle automation. Through the integration of advanced machine learning techniques and comprehensive experiments within a sophisticated driving simulator, GENIUS seeks to redefine TOC prediction in a wide range of real-world driving scenarios. Embracing an interdisciplinary approach, the project collaborates with experts in psychology and the automotive industry, ensuring a comprehensive and effective solution. GENIUS represents a significant leap forward in driver safety and experience in the age of automation, contributing to a safer and more efficient future on our roads.

Mots clés : conditionally automated vehicles, take over control, human machine interface

Participants :
- Université de Padoue (Italie) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- École polytechnique de Turin (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 215937.6 €
- Italdesign - giugiaro s.p.a. (Italie) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
Projet CRUSTY (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

Homochirality is one of the mysterious chemical benchmarks that is relevant to the origin of life. Biomacromolecules, constructed from the chiral building blocks, are mostly from exclusively either L- or D- structures, and the vast majority of the reactions in aqueous media are fine-tuned by chiral selectivity. However, although characterized by sum-frequency generation (SFG) spectroscopy and other techniques, whether and how the chiral biomolecules affect their hydration shells, through which intermolecular forces of such molecules are transmitted, are far from clear. Yet, the effect of perturbing the homochirality of biomacromolecules on their self-assembly is thus ambiguous. Here, I propose to use surface-anchored chiral short peptide molecules with a well-defined primary structure as a model. The structure and dynamics of the hydration shell of this peptide will be studied by chiral heterodyne detected sum-frequency (HD-SFG) spectroscopy, a nonlinear optical technique that provides information on hydration shells and their chirality. Using the solid phase peptide synthesis technique, chiral inversion will be induced at the level of a single monomer, blocks, and mixture of enantiomers. The self-assembly of peptide molecules will be characterized by atomic force microscopy for their morphology and SFG for their secondary structure. By quantitively comparing the spectrum of enantiomers, the dipole orientation of hydration water and their HB-network relaxation will be characterized using the O-H stretching band, which reflects thermodynamics and kinetics properties. Furthermore, the chiral inversion effect on self-assembly will be measured in the peptide’s amide I band, which reflects their packing. These results will shed light on chiral-induced water superstructure and self-assembly modulation, which is crucial for understanding the biological enrichment of homochirality and for anticancer/antiviral agent design.

Mots clés : chirality, hydration, sum frequency generation, peptide self assembly

Participants :
- Société Max-Planck pour le développement des sciences (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 217965.12 €
Projet SKM-REFORMAT (Horizon Europe, appel à projets 2024)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : SIGNED

Microtubules are formed by polymerization of tubulin heterodimers. Tubulin monomers rise from 16 genes each with their own spatiotemporal signature, resulting in a patterned microtubule network. As tubulin dimers define binding microtubule associated proteins (MAPs) and occurring post-translational modifications (PTMs), I wonder whether microtubule properties and patterns are encoded/defined by the tubulin isotypes themselves. This proposal aims at 1-confirmation of the expressed tubulin isotypes in skeletal muscle, depending on developmental stages, sex, and fiber type. 2-Understanding of how tubulin isotypes contribute to macroscopic phenotypes such as myoblasts fusion, general fiber organization and muscle contraction. 3-Deciphering of the molecular mechanisms at play upon tubulin isotype loss-of-function. 4-Assessement of potential beneficial effects of tubulin loss-of-function in diseases such as Duchenne muscular Dystrophy (DMD), Centronuclear Myopathy (CNM), and myasthenia. Using innovative in vitro differentiation tools, animal models and state of the art microscopy, I will explore all potential effects of selected tubulin isotypes, from macroscopic phenotypes to molecular mechanisms, as well as in disease. Expected techniques to use are: RT-q-PCR, co-cultures motoneurons-myoblasts, CRISPR/Cas9 mediated KO, shRNA KD, gene transfer by AAV injection, force measurement in vivo and ex vivo, immunohisto- and cytochemistry, live-imaging with fluorescent probes, and image analysis. Microtubule and tubulin being involved in many types of diseases (cancer, development, degeneration…) this project will lead to many economic, social and therapeutic benefits.

Mots clés : microtubules, tubulin isotypes, skeletal muscle, post translational modifications, motor unit, ipscs, crispr cas9 gene editing

Participants :
- Lyon-I université (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 242260.56 €
Projet BLASTEX (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Information Science and Engineering
Statut du projet : SIGNED

BLASTEX aims to jumpstart the development of self-centering (SC) reinforced concrete members that absorb blast energy with minimal damage, utilizing textile-reinforced concrete (TRC) strengthening layers for swift functional recovery. TRC layers dissipate energy through controlled crack formation in the cementitious matrix, while elastic textile reinforcement acts as a restorative spring, returning the structure to its original position after blast inertial loads are removed. While SC principles are well-established in seismic-resistant steel structures, their application in blast-resilient reinforced concrete remains unexplored. BLASTEX bridges this gap, leveraging SC to enhance blast resilience, eliminate the need for demolition, and reduce waste generation and associated emissions in new construction. During the outgoing phase at Virginia Tech (VT, US, 2 yr.), I will perform blast tests using the unique Shock Tube Laboratory, validate numerical models, and optimize SC design parameters. At Czech Technical University in Prague (CTU, CZ, incoming phase, 1 yr.), I will conduct numerical parametric studies and develop guidelines to facilitate SC implementation. At MOB-Bars (CZ, non-academic placement, 6 mo.), a start-up specializing in blast-resistant systems, I will examine SC protective design deployment in the commercial sector. With MSCA funding, I will benefit from three forms of mentorship: (i) close collaboration with Dr. Eric Jacques, a Shock Tube Laboratory director and expert on infrastructure resilience, blast protection, and energetic materials, (ii) academic leadership/research facility management training (Prof. Petr Konvalinka, former CTU Rector), and (iii) collaboration with Dr. Jindřich Fornůsek (MOB-Bars CEO). BLASTEX will facilitate two-way knowledge transfer across the Atlantic, enabling the researcher to find a future tenure-track position while honing his leadership/fundraising skills in blast research and the design of experimental facilities.

Mots clés : blast loading self centering concrete strengthening of structures blast protection textile reinforced concrete shock wave loading shock tube finite element analysis

Participants :
- Université technique de Prague (Rép. Tchèque) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 319273.2 €
- Mob-bars s.r.o (Rép. Tchèque) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Virginia Tech (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet PRISM (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

To address the global energy crisis, photocatalysis is one of the most advanced, green, and clean technologies for converting pollutants into fuel. However, low-cost photocatalysts with essential properties for hydrogen evolution reaction (HER) and CO2 reduction reaction (CO2RR) are very rare. After the accidental discovery of carbon nanodots (CNDs) in 2004, it is emerging as the rising star in photocatalysis due to readily low-cost synthesis, high water solubility, good photostability, and the position of conduction bands to afford catalytic reaction. However, on the one hand, research in visible-light-driven photocatalytic water splitting and CO2 reduction using CND catalyst is still in its infancy due to the very low molar extinction coefficients in the visible range. On the other hand, the contemporary literature fails to provide the actual mechanism of photocatalysis in CND materials. To date, the photocatalytic mechanism in CND materials mostly covered either single electron transfer or photo-base effect. Indeed, HER /CO2RR cannot be ensured by single electron transfer alone; electron transfer in conjunction with proton transfer, commonly referred to as proton-coupled electron transfer, is crucial to connect the actual multiple electrons and protons transfer. Therefore, exploring the proper photocatalytic mechanism in CND materials based on comprehensive globally analyzed time-resolved photophysical survey starting from femtoseconds to milliseconds and beyond using pump-probe transient absorption spectroscopy is an open research task. In addition, I will explore different synthetic strategies to increase molar extinction coefficients across the visible region to exploit the entire solar spectrum and increase the effective number of photogenerated carriers. Thus, our combined multidisciplinary approaches in synthesis, characterization, and application will definitely usher in a new era of nanomaterials research for new generations of energy sources.

Mots clés : photocatalytic mechanism, proton coupled electron transfer, vis light absorbing carbon nanodots, pump probe transient absorption, glotaran based global analysis, visible light driven photocatalysis

Participants :
- Centre for Cooperative Research in Biomaterials (Espagne) — Coordinator, beneficiary, Recherche, subvention : 181152.96 €
- Université Friedrich-Alexander d'Erlangen-Nuremberg (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet DAMOCLES (Horizon Europe, appel à projets 2022)
Action : Postdoctoral Fellowships - Global Fellowships
Panel : Chemistry
Statut du projet : SIGNED

The DAMOCLES project aims to apply data-driven modeling (i.e., molecular simulations combined with machine learning) to study and tailor metal oxide catalysts for CO2 hydrogenation processes (reverse water-gas shift, CO2 methanation, and CO2 to methanol), with the final goal of screening oxides in search of new and better catalytic materials. The starting point of the project is the newly-released OC22 oxide data set (from Meta FAIR and Ulissi's group) comprising approximately 50k adsorption energies of relevant molecules on multi-component oxide surfaces spanning 52 elements of the periodic table. State-of-the-art machine learning models (e.g., Gaussian process regression, and graph neural networks), will be applied for the prediction of relevant adsorption energies not included in the sparsely labeled OC22 dataset. New density-functional theory (DFT) calculations will target the adsorption energy of molecules not considered in the data set and activation energies of the elementary reactions of the CO2 hydrogenation paths. The catalytic performances (i.e., activity and selectivity) of the oxide surfaces in OC22 will be evaluated through microkinetic modeling. Active learning will be applied to iteratively improve the model predictions with additional DFT calculations targeting the parameters selected with sensitivity analysis and uncertainty quantification. The overarching goal of the DAMOCLES project is to understand the effects of the structure and composition of the catalyst surface in the processes of CO2 hydrogenation and identify new promising catalytic materials. This insight can guide experimental researchers in the synthesis of oxide materials with improved catalytic performances, thus helping the development of economically sustainable processes for the transformation of waste CO2 into useful chemicals and fuels.

Mots clés : catalyst screening multi component oxides atomistic modeling machine learning graph neural networks gaussian process regression

Participants :
- Université d'Aarhus (Danemark) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 196829.28 €
- Université Carnegie-Mellon (Etats-Unis) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
Projet GLAMOROUS (Horizon Europe, appel à projets 2023)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

In the field of Heritage conservation, the long-term preservation of archaeological and historical objects held in deposits is a subject of increasing concern. Artifacts made from two or more different materials in contact with each other, often stored under uncontrolled environmental conditions of temperature, humidity and clearness, can undergo degradation faster than thought. The contact areas and interstices between two materials are especially critical points for joint degradation phenomena and prolific ground for microbiological contaminants, especially in conditions of high humidity and in presence of organic pollutants. With this in mind, I am herein proposing an innovative project to investigate the degradation processes and microbiologically-induced corrosion of glass-metal objects that can occur in museum storage environments. I will capitalize on my own experience in Heritage science and glass alteration mechanisms, and on the competences and skills of the host institutions in electrochemistry and microbiologically induced corrosion to i) identify the major glass-metal joint corrosion phenomena and the microbiological contaminants present in museum storage deposits, ii) investigate the mechanisms underlying glass-metal corrosion and biocorrosion mechanisms by performing laboratory corrosion tests, and iii) experiment the application of electrochemical impedance spectroscopy (EIS) to monitor the previously described corrosion mechanisms. The proposed project will advance the understanding of joint (bio)-corrosion processes occurring at the interface between glass and metallic materials and will hopefully establish a new methodology to monitor such mechanisms. I will be extensively trained in corrosion processes and electrochemical techniques, microbial processes and related laboratory procedures, which will enable me to become an independent researcher and ultimately establish my own research group in the field of biodegradation and biocorrosion.

Mots clés : metal, glass, conservation, corrosion, alteration, mechanisms, bacteria, impedance spectroscopy

Participants :
- Université de Milan (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172750.08 €
- Ricerca sul Sistema Energetico (Italy) (Italie) — Partner, associated partner, Recherche, subvention : 0.0 €