Projet MS-RADAM (Horizon Europe, appel à projets 2024)
Action : Doctoral Networks
Panel : Physics
Statut du projet : SIGNED

The MS-RADAM DN will deliver a state-of-the-art research programme that will pioneer a new approach to reveal key nano- and larger-scale radiation biodamage phenomena based on multiscale modelling (MM) and its thorough validation using advanced experimental techniques and technological applications. In particular, the MS-RADAM research programme will focus on obtaining an advanced understanding of Radiation Damage (RADAM) phenomena induced by ion irradiation in biomolecular and biological systems relevant to the application of this knowledge in particle therapy and many other relevant areas of research and technology.  The unique feature of the MS-RADAM research programme is the MM description and measurement of key processes and phenomena occurring on different temporal and spatial scales during ion-beam irradiation incorporating: (i) propagation of charged particles in biological media, (ii) radiation-induced fast quantum processes within biomolecular environments, (iii) characterisation of the time and spatial evolution of track structures and localised energy deposition, (iv) slower nanoscale post-irradiation relaxation, chemical and thermalisation processes occurring in the irradiated biological media, (v) evaluation of biodamage accounting for specific radiobiological effects. To initiate such a programme and to provide industry, radiotherapy research community and many other related communities with a cohort of skilled researchers, MS-RADAM DN will train 14 Doctoral Candidates (DCs) in the methodology and skills needed for this emerging area of research and technology.  MS-RADAM DN contains leading academic and industrial partners with the necessary experience to provide the international, interdisciplinary and intersectoral training needed for the MS-RADAM research programme, whist also providing the DCs a unique opportunity to gain comprehensive training in the complementary and entrepreneurial skills for their further career development.

Mots clés : radiation physics, multiscale modelling, irradiation driven molecular dynamics, monte carlo methods, reactive force fields, collision processes, biodamage, nanochemistry

Participants :
- Commissariat à l’énergie atomique et aux énergies alternatives (France) — Partner, associated partner, Recherche, subvention : 0.0 €
- Université du Kent (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 697476.24 €
- Université de Heidelberg (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- National Physical Laboratory (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Carl von Ossietzky University of Oldenburg (Allemagne) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 580544.64 €
- Perpevit aps (Danemark) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Université Queen's de Belfast (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 348738.12 €
- Académie tchèque des sciences (Rép. Tchèque) — Partner, beneficiary, Recherche, subvention : 280022.76 €
- Université Paris-Saclay (France) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Institut de technologie chimique de Prague (Rép. Tchèque) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- MBN Research Center (Allemagne) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 580544.64 €
- University College de Londres (Royaume-Uni) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 697476.24 €
- Université Johann Wolfgang Goethe de Francfort-sur-le-Main (Allemagne) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- Université de Groningue (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 305285.76 €
- Université internationale de Koutaïssi (Géorgie) — Partner, associated partner, Organismes publics (hors enseignement & recherche), subvention : 0.0 €
- Université Masaryk (Rép. Tchèque) — Partner, associated partner, Enseignement supérieur ou secondaire, subvention : 0.0 €
- University Medical Center Groningen (Pays-Bas) — Partner, beneficiary, Enseignement supérieur ou secondaire, subvention : 305285.76 €
- Raysearch laboratories ab (publ) (Suède) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Minerva health & care communications ltd (Royaume-Uni) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Fiz frankfurter innovationszentrum biotechnologie gmbh (Allemagne) — Partner, associated partner, Organismes privés (hors enseignement), subvention : 0.0 €
- Centre national de la recherche scientifique (France) — Partner, beneficiary, Recherche, subvention : 314669.16 €
- Czech Acad Sci J Heyrovský Inst Phys Chem (Rép. Tchèque) — Partner, beneficiary, Autres, subvention : 280022.76 €