Data-Gouv-ML/pcri-actions-marie-curie-participations-et-projets-laureats huggingface dataset:
Projet SolSupPol (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

During the last three decades, tremendous progress has been made in the field of Supramolecular Polymers (SPs), and several fundamental issues have been disclosed. As a result, these materials are reaching technological maturity. The intrinsic dynamicity and responsive properties of SPs render them intriguing candidates for a plethora of applications, ranging from life-like systems to optoelectronics. Thus, investigation on SPs is expected to have a profound impact on the knowledge-based society. Remarkably, the role of solvent in supramolecular polymerization is still poorly understood. The current picture of solvent effects on SPs is fragmented and mainly descriptive. With SolSupPol, I propose a detailed study of the role of competitive solvent interactions in the helical bias and thermal behaviour of SPs in solution, based on the use of chiral solvents. Combining a systematic investigation on solvent effects at a macroscopic level with a microscopic study of their molecular origin, an unprecedent control over competitive solvent interactions in supramolecular polymerization will be achieved. Hence, I aim to exploit solvent effects to tune the properties of SPs in the bulk. These findings will constitute a proof-of-concept, revealing emerging solvent-induced structure-property relationships in the solid state. The project includes the synthesis of a library of monomers, the empirical and theoretical study of their assembly in solution, the preparation and characterization of thin films, and the probing of the spin-filtering and long-range exciton transfer properties of solvent-induced chiral supramolecular structures in the bulk. The outcomes of this project will enable the design of tailored interactions between SPs and solvents and will foster the development of functional, adaptive materials based on solvent effects. Dissemination and communication activities will guarantee the great impact of SolSupPol.

Mots clés : supramolecular polymers, supramolecular assemblies, self organization, non covalent interactions, helical structures, helicity control, supramolecular chirality, circular dichroism, solvents, monomers

Participants :
- Eindhoven University of Technology (Pays-Bas) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 175572.48 €
Projet TBI-WAVES (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Mathematics
Statut du projet : SIGNED

During the past decade, the brain has been the subject of numerous studies aimed at understanding its function and its behaviour. An important challenge lies in the prediction and the treatment of Traumatic Brain Injury (TBI), which is a major source of death and disability worldwide. In the mechanics community, important efforts have been dedicated to the mathematical description of the response of brain matter to forces, and to the simulation of traumatic events. Nevertheless, further progress is of utmost importance for applications in biomedical engineering and medicine. In facts, despite clear evidence that dynamic solicitations such as impacts play a crucial role in head traumas, several time-dependent effects are often neglected in the modelling (inertia, fluid content, viscous effects, swelling). The main goal of the TBI-WAVES project is to improve the mechanical and computational modelling of head traumas. A first aim is to improve the mechanical modelling of brain matter by accounting for the above commonly neglected effects. A second aim is to develop dedicated head impact simulation tools. The problem will be approached from theoretical and numerical perspectives, based both on the applicant’s and the host laboratory’s expertise. The training programme is exhaustive and will allow the applicant to grow as an independent researcher. The proposed research will foster further developments in this direction, a step which is fundamental in healthcare and for the benefit of society. The applicant is a Franco-German dual citizen, trained in France in applied mathematics, theoretical mechanics, and computational mechanics. He publishes articles in international scientific journals, with topics in applied mathematics and other disciplines. He is requesting funds for two years, to work within Prof. Michel Destrade’s team at NUI Galway. A six-month secondment at the University of Trento is planned.

Mots clés : traumatic brain injury, soft tissues, nonlinear waves, mechanical modelling, biomechanics

Participants :
- National University of Ireland (Irlande) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 184590.72 €
Projet Q-ANNTENNA (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Physics
Statut du projet : CLOSED

During the recent years, modern machine learning (ML) has sparked a revolution in areas so diverse as computer vision, voice recognition, medical diagnosis and finance. On its own, quantum information processing (QIP) has also gained tremendous momentum and a novel field, quantum machine learning (QML), has emerged from the intersection of the two disciplines. Interestingly, much of the understanding underlying the last revolution of ML is strongly connected to insights gained from condensed matter and statistical physics. It is then natural to use well-understood techniques to describe quantum many-body systems, namely, tensor networks (TN) in the context of ML. The objective of Q-ANNTENNA is to develop a thorough understanding between ML processes and TN. The action will involve state-of-the-art theoretical research at the frontiers of QIP, TN and ML: (1) describing ML processes within the TN formalism, (2) importing TN insights into ML, (3) studying the renormalization process and (4) assessing physical implementations. The experienced researcher, Dr. Jordi Tura, is an expert in QIP in many-body systems. The supervisor, Prof. J. I. Cirac, is a world-expert in QIP, TN and quantum computation, head of the Theory division of the Max Planck Institute of Quantum Optics (MPQ) since 2001. The combined expertise between the fellow and the host is uniquely suited to establish Q-ANNTENNA as a ground-breaking framework for understanding the connections between QIP, ML and TN. The action has a tremendous potential impact onto industry and prospects for patents are likely. In addition, it will contribute to EU’s excellence in QML research, where North America is leading industrial and scientific efforts –by far. The action will greatly increase the applicant’s mobility within EU, create a large network of collaborators for him and MPQ and shape his future career options, with the long-term goal of becoming an independent scientist and establishing his own research group.

Mots clés : quantum machine learning, tensor networks

Participants :
- Max Planck Society (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 159460.8 €
Projet TransIt (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Social Sciences and Humanities
Statut du projet : CLOSED

During the second half of eighteenth-century, the Italian peninsula was involved in the so-called “reading revolution”, a process characterized by an important increase of the number and diversification of the interests of the public. Professors, students, members of technical-administrative élites, but also a wider community of readers were significantly interested in Italian and foreign books, such as novels, scientific and technical manuals, travel literature or philosophical and historical works. In particular, scientific publications coming from other European countries significantly attracted the attention of readers having a strong professional interest or a simple curiosity in medical science, agronomy or natural sciences. The largest part of these texts was available to “common” readers – who knew only their own language – mainly through translations, that – as numerous scholars have highlighted – should be conceived not only as linguistic activities, but also as cultural practices. Starting from this final assumption and trying to combine different approaches (cultural history of translations, history of publishing, study of cultural transfers), the project TransIt aims to give a contribution to our understanding of the processes of circulation and reception of scientific ideas in Italy during the Enlightenment, by examining a specific corpus of translations of English and French works, and, especially, the role played by translators and publishers. The study of translations – and of translators’ and publishers’ policies in particular – is an useful tool to investigate the ways in which ideas were re-elaborated and assimilated in new cultural, social and political contexts. Translators and publishers acted as authentic “cultural mediators”, always very attentive to satisfy public’s demands, by adopting different textual and paratextual strategies aimed at adapting the new foreign scientific theories and languages for the new readers’ taste and knowledge.

Mots clés : enlightenment, translations, history of science, book history, readership

Participants :
- European University Institute (Italie) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 172477.2 €
Projet IminoBoron (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : CLOSED

Dynamic polymers, which are able to break and reform due to the dynamic nature of their linkages, can be considered as a new class of smart materials, since they can be altered and/or respond to different external stimuli. We propose a new class of dynamic, conjugated polymers based on the reversible iminoboronate ester bonding motif. Simple monomers containing aldehyde, amine, and boronic acid functionalities will polymerize together with diols to produce iminoboronate ester polymers. The presence of orthogonal dynamic imine and boronate ester bonds will allow us to develop easily functionalizable, and thus tuneable, multicomponent polymer materials that possess the ability to reorganise or adapt in response to various external stimuli. The incorporation of electronically distinct diols, will permit us to tune the photophysical and chemical properties of the conjugated polyimine polymer backbone, enabling the possibility to attain the desired material properties. These multifunctional materials will be investigated as fluorescent polyreceptors for specific diols and as controllably crosslinkable or decrosslinkable materials with the addition or displacement of tetrols. Moreover, development of these high-value smart materials will lay the groundwork for the next generation of multifunctional devices, such as blue-light-emitting polymers with superior efficiency and electrochemical stability to the state-of-the-art poly(fluorene) and GaN (O)LEDs.


Participants :
- University of Cambridge (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet MIRA (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Life Sciences
Statut du projet : CLOSED

Dysregulation in the balance of CD4+ T helper cell populations can severely alter susceptibility to a number of chronic inflammatory diseases, including inflammatory bowel disease (IBD). The incidence of IBD is dramatically increasing in Europe and worldwide and its therapy represents an important unmet medical need, since a significant proportion of patients fail to respond to currently available immunotherapies. Therefore, a better characterization of the immunological events underlying each form of IBD is of foremost importance. Increasing evidence points to the pivotal role of a dysregulated mucosal immune response to the intestinal microbiota in the pathogenesis of IBD. However, little is known about the mechanisms contributing to the generation of commensal-specific adaptive immune responses, and whether their differential localization can shape severity and anatomical extent of the disease. Indeed, the intestines comprise anatomically distinct regions that are exposed to different luminal antigens and this diversity eventually determines a regionalization of intestinal immune functions and microbiota-specific T cell responses. The aim of this proposal is to deeply characterize microbiota-specific T cell responses generated under different inflammatory conditions, in terms of differentiation, plasticity, heterogeneity, function and homing potential. To this aim, the proposed work will combine the use of CBir1 TCR transgenic mice, whose T cells recognize a microbial antigen that is immunodominant in IBD patients, and cutting-edge techniques such as single-cell RNA sequencing. By modelling the microbiota-specific immune response in vivo in the context of gut inflammation, I will characterize the function and homing properties of microbiota-specific T cells at the population and single-cell level, aiming at identifying new therapeutic targets for the treatment of localized forms of gut inflammation.

Mots clés : tissue specific t cell trafficking

Participants :
- Karolinska Institutet (Suède) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 173857.2 €
Projet E3I ECLAUSion (Horizon 2020, appel à projets 2017)
Action : Cofund Doctoral programme
Statut du projet : SIGNED

E3I ECLAUSion, a joint venture between Ecole Centrale de Lyon (ECL) and RMIT University, Melbourne Australia aims to build a highly nurturing and multi-faceted PhD training environment that would benefit the emergence (‘eclosion’) of the next generation - 10 doctoral fellows in 2 cohorts- of not only highly skilled researchers but also entrepreneurs with an international mind-set and interdisciplinary training. Specifically ECLAUSion, in line with the MSCA guidelines, the EU principles for Innovative doctoral training and the code of conduct, aims to i) Reinforce research excellence in ECL in partnership with RMIT and increase scientific output and international visibility; ii) Expand on existing doctoral programs by attracting highly promising international early career researchers to ECL and providing a nurturing environment with global reach (both in terms of scientific supervision, mentoring, working conditions, administrative support and social life). We envision two calls being organized, with 5 doctoral contracts per call being offered (total number of PhDs offered 10) so that every researcher can receive their PhD degree during the 5 years program; iii) Educate and train these ESRs; enhance their research and transferable skills with a 3i dimension by offering them Interdisciplinary research options, exposure to Industry (both at local, regional and international levels), and an inherently International network to maximise their opportunities and their emergence into successful professionals in their future careers iv) Leverage the existing rich biotech and ICT local/regional/global ecosystem and capitalise on it to develop new synergies between academia and the private sectors and more generally v) Strengthen EU-Australia research collaboration in key areas for investment and growth in particular in Health; Biotechnology, Environment; Energy; Information and communications technologies; Nanotechnologies, materials and production technology.

Mots clés : international, intersectoral, interdisciplinary, nurturing and multi faceted phd training program, career development, industry engagement, eu australia research collaboration, ecl rmit joint venture

Participants :
- Centrale Lyon (France) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 784800.0 €
Projet EARLINESS.eu (Horizon 2020, appel à projets 2015)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : CLOSED

EARLINESS.eu proposes a new European early warning system (EWS), able to identify and signal economic vulnerabilities in order to allow policy makers to intervene in a timely manner. The ongoing European financial crisis poses a serious challenge to the stability of the euro area and growth prospects in Europe. The aim of the EARLINESS.eu project is to implement a EWS for systemic risk to prevent and mitigate financial instability by exploiting the linkages among the financial markets and the real economy. Given the potentially high and unsustainable costs caused by systemic crises, it is of fundamental importance to establish a comprehensive system of early warning signals and indicators to monitor them. Recent studies suggest that empirical analysis should focus on the macroeconomic and financial shocks transmission across countries, allowing for nonlinear propagation of these shocks. The innovative purpose of EARLINESS is to fill this gap by modelling nonlinear interactions between the financial market and the macroeconomic system. The main challenge is the realization of a comprehensive system able to detect and measure each marginal change in the sources of systemic risk by developing an innovative building block structure. A novel Dynamic Quantile Factors model is introduced to extract the latent signal of systemic risks at micro and macro level from a panel of institutions belonging to the European area and partner countries. The project uses state-of-the-art systemic risk measures and integrates new methodologies in financial econometrics, systemic risk measurement and big data analysis tools. According to the Macroprudential Research Network of the ECB, the implementation of macroprudential policy is still at an early stage and much effort is needed to support policymakers in designing mechanisms for prudential tools. The EARLINESS project can deliver an important contribution to this.

Mots clés : early warning system, systemic risk measures, financial stability, macro financial linkages, network, sparsity, dynamic quantiles

Participants :
- Gesellschaft fur kapitalmarktforschung ev (Allemagne) — Coordinator, beneficiary, Recherche, subvention : 171460.8 €
Projet ECO_REBUS (Horizon 2020, appel à projets 2016)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Economic Sciences
Statut du projet : CLOSED

ECO_REBUS aims to get a closer understanding of the process through which firms adopt and operate public voluntary eco-innovation policies, a kind of policy that has become increasingly central in policy makers’ agenda. To achieve this objective, the project assigns a specific role to the concept of business model, defined as the configuration of customer sensing, customer engagement, value delivery and monetization components, that captures causal links between value creation and value capture at the business level. Specifically, the project will integrate the literature on eco-innovation and the one on business model to address how and why business model can make eco-innovation a central part of the firm’s value creation and appropriation. To do this, ECO_REBUS will investigate -by a cognitive and processual perspective- the phases through which public voluntary eco-innovation policies are adopted and operated by firms. To do this, first, the researcher will carry out both a literature review at the intersection of eco-innovation policy and business models, and also a review of business model change. Secondly, interviews with top managers team members will be carried out with a cognitive approach to explore how they evaluate the potential impacts of future eco-innovation adoption by the lens of business model. Third, a comparative case study on firms and multiple business units will enable to explore the processual aspects aiming to understand how and why changing the business model might help firms successfully face the challenge of eco-innovation policy adoption, and get positive economic gains. Some original and innovative aspects characterize ECO_REBUS. Among others, its processual and cognitive contribution showing how and why some firms profit being green; its multiple level of analysis, and its inter-disciplinary contribution by integrating knowledge from the field of environmental management and the field of business model research.

Mots clés : eco innovation, voluntary environmental policies, business model, environmental policies

Participants :
- University of London (Royaume-Uni) — Coordinator, beneficiary, Enseignement supérieur ou secondaire, subvention : 195454.8 €
Projet EPROMILK (Horizon 2020, appel à projets 2020)
Action : Postdoctoral Fellowships - European Fellowships
Panel : Chemistry
Statut du projet : SIGNED

EPROMILK is a career development scientific project aimed at offering an experienced researcher (Dr. Eva González) a high-quality research and training programme in the field of Biosensors for Food Safety monitoring, connecting the knowledge of multidisciplinary fields such as bioelectroanalytical chemistry and advanced manufacturing technologies. Combining the researcher’s previous experience in developing electrochemical biosensing technologies, including protease detection and Point-of-Care diagnostics devices, and the hosting institution (BIOLAN Microbiosensores S.L.) proven expertise in developing electrochemical biosensors for food industry, in the framework of EPROMILK we will work on the design and development of biosensors applied to the detection of protease activity in milk for the prediction of shelf-life of dairy products. This will allow the identification and subsequently recall of Ultra-high temperature (UHT) milk batches showing premature spoilage potential, avoiding their arrival to the consumer. Along with these scientific objectives, the project also focuses on developing the researcher’s transferable skills by strengthening communication, scientific writing, supervision and international mobility, preparing her to become an independent well-established scientist, either in the academic or industrial sector. EPROMILK will link both basic and applied research thanks to the scientific excellence and industrial environment of the hosting organisation and of the technological research centre during the secondment (CNTA). In this sense, the researcher will be given a promising opportunity to transfer knowledge and results between academia and industry. After all, EPROMILK aims at providing excellent working conditions to an ambitious international scientific talent in a high-level industrial and research environment, helping her to build her research career in Europe while contributing to the European Research Area development.

Mots clés : biosensor, protease detection, milk, portable, screen printed electrodes, faradaic impedance spectroscopy, voltammetry, anti fouling surface

Participants :
- Biolan microbiosensores sl (Espagne) — Coordinator, beneficiary, Organismes privés (hors enseignement), subvention : 172932.48 €