Projet ANR-13-KBBE-0004 – GEWIDIS : Exploiting Genome Wide Diversity for disease resistance improvement in oilseed rape
Programme : Food & Feed: crop yiels and nutrition security in the context of clinate change (PLANT-KBBE) 2013
Année de financement : 2013
Coordinateur du projet : Madame Régine DELOURME (UMR1349 IGEPP Institute of Genetics, Environment and Plant protection)
Partenaires : BIOGEMMA; Terres Inovia; SYNGENTA FRANCE SAS; Institut de Génétique Environnement et Protection des Plantes
Montant : 412590.0 euros
Date de début : 2014
Durée : 36 mois
Résumé : The development of integrated pest management will more and more rely upon the identification,
utilization and ultimate deployment of effective and durable host resistances to the most important
pathogens through the design of new multi-resistant varieties. In oilseed rape, many efforts have aimed
at describing the genetic architecture of disease resistance but these studies were performed
independently for each disease. Moreover, there is a lack of genetic variability for resistance within OSR
for many diseases and some valuable resistance sources have been identified in the progenitors of
OSR, especially in B. oleracea. Thus, in order to progress towards multi-resistant varieties, there is a
need for a better integration of researches on genetics of disease resistance in Brassica species and for
a wider exploitation of Brassica diversity through the identification of valuable resistance alleles for
breeding.
The general objective of GeWiDis project is to perform a comparative analysis of the structural
organization and allelic diversity of resistance factors to most important diseases of OSR in diverse
Brassica materials and to optimize the strategy of breeding multi-resistant varieties through the
exploitation of a wide genetic diversity. The project aims to (i) investigate the localisation of the
resistance factors involved in the different diseases and their relationships (common/specific regions,
positive/negative correlations), (ii) study the impact of Brassica genome organization on the genetic
diversity and evolution of these resistance factors among different Brassica materials, (iii) identify key
genomic regions for resistance and valuable resistance alleles in the Brassica resources and associated
makers to be used in breeding and (iv) set up an optimized scheme for the introgression of new
resistance variability in OSR.
This project will take advantage of the complementarities of the partners from the two countries to
generate considerable amounts of new knowledge on OSR resistance through a multi-disease
integrated approach and high throughput phenotypic and genomic data production on very original
Brassica genetic resources (core collections of OSR and B. oleracea, semi-synthetic and synthetic B.
napus). Genome wide association studies and fine scale sequence analyses in key regions will allow to
determine how polyploidy affects resistance factors organization/allelic diversity and resistance
expression. Common and specific key regions for resistance to the different diseases will be identified
as well as resistance haplotypes/alleles either already introduced into OSR or to be introgressed from
diploid species through an optimized scheme. GeWiDis, through the combined efforts of public and
private partners, will then bring new resources and tools for an efficient breeding of multi-resistant
varieties adapted to the current and future environmental context.