Life as We Know It (film)
Life As We Know It is a 2010 American romantic comedy-drama film directed by Greg Berlanti, starring Katherine Heigl and Josh Duhamel.
 It was released on October 8, 2010, after sneak previews in 811 theaters on October 2, 2010.
Invest in Love
"Invest in Love" is the eighth episode of the sixth season of the American television medical drama "Grey's Anatomy", and the show's 110th episode overall.
 Written by Stacy McKee and directed by Jessica Yu, the episode was originally broadcast on the American Broadcasting Company (ABC) in the United States on November 5, 2009.
 "Grey's Anatomy" centers around a group of young doctors, training to be seasoned professionals.
 In this episode, Dr. Arizona Robbins (Jessica Capshaw) is stunned when her longtime patient's parents offer the hospital a donation of twenty-five million dollars.
 Katherine Heigl (Dr. Izzie Stevens) was absent from the episode, as she was filming the 2010 blockbuster "Life as We Know It".
 The original episode broadcast was ranked #3 for the night and would have 13.95 million viewers, garnered a 5.1/13 Nielsen rating/share in the 18–49 demographic.
Killers (2010 film)
Killers is a 2010 American action comedy film directed by Robert Luketic and starring Katherine Heigl and Ashton Kutcher.
 The film was released on June 4, 2010.
 The film centers on a young woman (Heigl) who meets the man of her dreams (Kutcher) who turns out to be an assassin.
Jenny's Wedding
Jenny's Wedding is a 2015 American independent film written and directed by Mary Agnes Donoghue.
 The film stars Katherine Heigl, Alexis Bledel, Tom Wilkinson, Linda Emond, Grace Gummer and Matthew Metzger.
 Heigl plays Jenny, a woman who finally decides to get married, but her choice of partner tears her conventional family apart.
 "Jenny's Wedding" was filmed on location in Cleveland from October 2013.
 An Indiegogo campaign was later launched to help raise money for post-production costs.
 The film was released on July 31, 2015 in a limited release by IFC Films.
Vermilion Escada dress of Katherine Heigl
The vermilion Escada dress of Katherine Heigl refers to the vermilion red dress worn by Katherine Heigl at the 80th Academy Awards on February 24, 2008. "
Cosmopolitan" magazine cited the dress as one of the Best Oscar dresses of all time, saying, "From the blond curls and red lips down to the train of her Escada goddess gown, Katherine’s Old Hollywood style finalized her reputation as a sex bomb.
 We love the way she looked totally relaxed in the dress, as if she’d been wearing it to lounge around in all day and just happened to show up at the Academy Awards."
Izzie Stevens
Isobel Katherine "Izzie" Stevens, M.D. is a fictional character from the medical drama television series "Grey's Anatomy", which airs on the American Broadcasting Company (ABC) in the United States.
 The character was created by series producer Shonda Rhimes, and was portrayed by actress Katherine Heigl from 2005 to 2010.
 Introduced as a surgical intern at the fictional Seattle Grace Hospital, Izzie worked her way up to resident level, while her relationships with her colleagues Meredith Grey (Ellen Pompeo), Cristina Yang (Sandra Oh), George O'Malley (T.R. Knight) and Alex Karev (Justin Chambers) formed a focal point of the series.
Grey's Anatomy (season 6)
The sixth season of the American television medical drama "Grey's Anatomy", commenced airing on the American Broadcasting Company (ABC) in the United States on September 24, 2009, and concluded on May 20, 2010.
 The season was produced by ABC Studios, in association with ShondaLand Production Company and The Mark Gordon Company; the showrunner being Shonda Rhimes.
 Actors Ellen Pompeo, Sandra Oh, Katherine Heigl, and Justin Chambers reprised their roles as surgical residents Meredith Grey, Cristina Yang, Izzie Stevens, and Alex Karev, respectively.
 Heigl was released from her contract in the middle of the season, while T.R. Knight did not appear as George O'Malley, because Knight was released from his contract at the conclusion of season five.
 Main cast members Patrick Dempsey, Chandra Wilson, James Pickens, Jr., Sara Ramirez, Eric Dane, Chyler Leigh, and Kevin McKidd also returned, while previous recurring star Jessica Capshaw was promoted to a series regular, and Kim Raver was given star billing after the commencement of the season.
Love Comes Softly
Love Comes Softly is a 2003 Christian drama television movie set in the 19th century, based on a series of books by Janette Oke.
 It originally aired on Hallmark Channel in 2003.
 It was directed by Michael Landon Jr., and stars Katherine Heigl as a young woman named Marty Claridge.
Jackie &amp; Ryan
Jackie & Ryan (released in the UK and South Africa as Love Me Like You Do) is a 2014 American romantic drama film written and directed by Ami Canaan Mann, starring Katherine Heigl and Ben Barnes.
The Nut Job
The Nut Job is a 2014 3D computer-animated heist-comedy film directed by Peter Lepeniotis, who also wrote the film with Lorne Cameron.
 It stars the voices of Will Arnett, Brendan Fraser, Gabriel Iglesias, Jeff Dunham, Liam Neeson and Katherine Heigl.
 Stephen Lang, Maya Rudolph and Sarah Gadon also star in supporting roles.
 The film is based on Lepeniotis' 2005 short animated film "Surly Squirrel".
 Produced by Gulfstream Pictures, Redrover International and ToonBox Entertainment, it was released in the United States on January 17, 2014, by Open Road Films.
 With a budget of $42.8 million, it is the most expensive animated film co-produced in South Korea.
 The film grossed $64.3 million in North America, for a worldwide total of $120.8 million.

Question: Who directed the 2010 film that caused Katherine Heigl to be absent from "Invest in Love"?
Answer: Greg Berlanti