Takotsubo syndrome in the setting of cardiac pacing: A review of mechanistic and clinical perspectives
Journal: Heart Failure Reviews
Year: 2026

Takotsubo syndrome (TTS) is a reversible form of acute cardiac syndrome usually arising in response to various emotional and physical stressors. TTS due to cardiac pacing has been an uncommon phenomenon mostly attributable to a variety of periprocedural conventional stressors including anxiety, pain and low cardiac output. Interestingly, intraventricular mechanical factors might also play a pivotal role in TTS evolution due to cardiac pacing. Notably, this phenomenon may be potentially underdiag