EVALUATION OF CYTOTOXICITY AND PRO-APOPTOTIC EFFECTS OF NEW CYP17A1 INHIBITORS
Journal: Cardiometry
Year: 2022

The CYP17A1 inhibitors are used to treat castration-resistant prostate cancer. However, the existing shortcomings (side effects and low bio-availability) make the search, synthesis, and evaluation of the biological properties of new agents relevant. The aim of our research work was to investigate the cytotoxic and proapoptotic properties of new compounds: alsevirone and LA-91.