Effect of IL-2 T-330G polymorphism on markers of systemic inflammation, intestinal permeability and vascular regulation in post-COVID patients
Journal: Medical Immunology (Russia)
Year: 2024

Recent studies suggest a role of genetic factors, i.e., polymorphisms of genes controlling the main immune components of antiviral response, and the risk of COVID-19 infection, severe course and lethal outcomes of the disease, as well as development of clinical or laboratory changes in the post-COVID period. Interleukin-2 (IL-2) plays an important role in immunopathology of COVID-19. However, there are only few data on the impact of single nucleotide polymorphisms, e.g., IL-2 330T/G (rs2069762)