LIPID LOWERING BY STATIN; EFFECT OF ADMINISTRATION ON BETA THROMBOGLOBULIN; A MARKER OF PLATELET REACTIVITY IN HIGH FAT DIET INDUCED OBESE MALE AND FEMALE SPRAGUE DAWLEY RATS
Journal: The Professional Medical Journal
Year: 2017

Objectives: To observe the effect of lipid lowering by atorvastatin administrationon platelet reactivity by measuring serum beta thromboglobulin concentration in male andfemale Sprague Dawley rats. Study Design: Randomized control trial (RCT). Place of study:The study was conducted at Physiology department, Army Medical College, Rawalpindi. Animalhandling, obesity induction, drug administration and sample collection were done at NationalInstitute of Health (NIH), Islamabad and biochemical assays