COMPARATIVE EFFICACY OF “FIRST STEP” ANTIHYPERTENSIVE DRUG COMBINATIONS IN PATIENTS WITH ARTERIAL HYPERTENSION AND OBSTRUCTIVE SLEEP APNEA SYNDROME
Journal: Ulyanovsk Medico-biological Journal
Year: 2021

Hypertension in combination with obstructive sleep apnea syndrome (OSAS) is a common comorbid pathology that significantly reduces patients’ quality of life and longevity. Blood pressure control in such patients is a serious problem, since there are no clear treatment algorithms due to insufficient evidence base. The objective of the paper is to compare the efficacy and tolerability of the initial two-drug antihypertensive combinations (perindopril / indapamide and perindopril / amlodipine) as "