Investigation of protection of Tongxinluo capsule on renal ischemical reperfusion injury
Journal: Hebei Journal of Traditional Chinese Medicine
Year: 2010

Objective To investigate the influence of Tongxinluo capsule(TXLC) on renal ischemic-reperfusion(I/R) injury and the possible protective mechanisms.Methods 30 male Wistar rats were randomly divided into 3 groups(n=10 in each group): sham operation group(S group);ischemia-reperfusion group(I/R group) and I/R+ TXLC group(I/R+ T group).The models were established through clamping renal pedicles for 45 minutes following 24-hour reperfusion.TXLC(1.0 g/kg,bid) was administered intragastrically for 7 d