Unusual, Uncommon, Yet Intriguing, but Significant Causes of Kounis Syndrome: A Clinical Paradox, Important Medications and Chemicals Used To Treat Kounis Syndrome and Myocardial Infarction Can Cause Kounis Syndrome
Journal: Preprints.org
Year: 2025

The degranulation of mast cells and other interacting and linked cells, including T-lymphocytes, macrophages, eosinophils, and platelets, as well as a range of inflammatory mediators produced during an anaphylactic or allergic reaction, are the main causes of Kounis syndrome. Acute ischemia episodes, coronary spasm, atheromatous plaque erosion/rupture, and platelet activation can all be caused by histamine, tryptase, arachidonic acid derivatives, and chymase in the Kounis syndrome cascade. Kouni