pH-responsive Chitosan/alginate as a Suitable Nanocarrier for Efficient Oral Delivery of Catechin in Aluminum Chloride-induced Brain Injury
Journal: Research Square
Year: 2022

Abstract Although, numerous clinical studies have shown the efficacy of catechin as a main bioactive compound in green tea, which has demonstrated a capacity in prevention and treatment of a wide range of diseases, it has poor potential for bioavailability and absorption in the gastrointestinal tract. This study is aimed to investigate the effect of chitosan alginate nanocarriers encapsulated catechin in an aluminum chloride-induced dementia paradigm. The catechin-loaded chitosan-alginate nanoca