MAJOR LYMPHOCYTE SUBPOPULATIONS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND THEIR ASSOCIATIONS WITH CELLULAR AND HUMORAL ANTI-ENDOTOXIN IMMUNITY
Journal: Medical Immunology (Russia)
Year: 2015

At the present time, systemic lupus erythematosus (SLE) takes the leading place among systemic autoimmune disorders. Despite considerable progress in understanding basic pathogenesis of this disease, many subtle mechanisms of progressive inflammation in SLE are still unknown. It has been discovered that the persistent self-maintenance factors of autoimmune inflammation could be represented by lipopolysaccharides or endotoxins of Gram-negative intestinal bacteria. The objective of this study was