Reporter-expressing viruses for antiviral drug discovery research
Journal: Frontiers in Cellular and Infection Microbiology
Year: 2025

Viruses continue to pose major global health challenges, with recent pandemics underscoring the urgent need for effective antiviral therapeutics. While vaccines have reduced the burden of some viral diseases, many remain difficult to control. Antiviral drug discovery relies on identifying and validating suitable targets through both target-based and phenotype-based screening strategies. Traditional antiviral assays are accurate but labor-intensive and not easily adaptable for high-throughput ana