Identifying missing pieces in color vision defects: a genome-wide association study in Silk Road populations
Journal: Frontiers in Genetics
Year: 2023

<b>Introduction:</b> Color vision defects (CVDs) are conditions characterized by the alteration of normal trichromatic vision. CVDs can arise as the result of alterations in three genes (<i>OPN1LW</i>, <i>OPN1MW</i>, <i>OPN1SW</i>) or as a combination of genetic predisposition and environmental factors. To date, apart from Mendelian CVDs forms, nothing is known about multifactorial CVDs forms. <b>Materials and Methods:</b> Five hundred and twenty individuals from Silk Road isolated communities w