Infectious Properties of Avian Influenza A/H5N1 Virus Strains Studied by means of Experiments on Mice
Journal: Problems of Particularly Dangerous Infections
Year: 2011

The studied strains of avian influenza virus A/H5N1 (AIV), isolated in the territory of the Russian Federation and CIS countries, can be classified into three groups according to their virulence for mice after intranasal and aerosol challenging: highly virulent strains [50 % aerosol lethal dose (ALD 50 ) - 50 )] - A/Chicken/Kurgan/05/2005, A/Chicken/Crimea/04/2005, A/Chicken/Omsk/06, A/Chicken/Krasnodar/02/06, A/Chicken/Dagestan/06; strains with mid-level virulence [LD 50 (ALD 50 ) - 3,0-4,5 lg