FEATURES OF GROWTH AND DEVELOPMENT OF B16 MELANOMA IN SEXUALLY MATURE MALE C57BLACK/6 MICE IN MODELING POST-TRAUMATIC STRESS DISORDER
Journal: Cardiometry
Year: 2023

It is well known that extraordinary stress or chronic exposure to stressors is characterized by adverse immunological consequences due to stress-induced immunosuppression. It has been established that stress causes an increased incidence of malignant tumors and also worsens the prognosis in patients with already existing tumors. Among the mechanisms of carcinogenesis under stress, there is an increase in the level of cortisol, which has a significant inhibitory effect on the immune system and th