DOSE-DEPENDENT CARDIOTROPIC EFFECTS OF ACETYLSALICYLATES
Journal: Scientific Notes of V I Vernadsky Crimean Federal University Biology Chemistry
Year: 2021

The effect of acetylsalicylic acid and its complex compounds with the metals cobalt (Co2+), zinc (Zn2+), nickel (Ni2+) and manganese (Mn2+) at doses of 5, 10 and 20 mg/kg on the parameters of the rat cardiorespiratory system was studied. It is shown that in the process of complexation of acetylsalicylic acid with bimetals, there is not only an increase or decrease in certain effects inherent in the precursor molecule – acetylsalicylic acid, but also the appearance of new properties, the manifest