Kondanse 1,4-Dihidropiridin-3-Karboksilat Türevleri ve Kalsiyum Modülatör Etkileri
Journal: Hacettepe University Institutional Repository (hacettepe.edu.tr)
Year: 2015

In this study sixteen 2,6,6-trimethyl-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (compound 1-16) have been synthesized. The synthesis of the compounds was realised by the reaction of the 4,4-dimethyl-1,3-cyclohexanedione, appropriate acetoacetate derivates and naphthalene carbaldehyde in the presence of ammonium acetate in methanol. The structure of the compounds were confirmed by IR, 1H-NMR, 13C-NMR, mass spectroscopy and elemental analyses. The structure of the compound 10 was a