Assessment of Resistance to Lytic Effect of Diagnostic Cholera Bacteriophage El Tor in Non-Toxigenic Vibrio cholerae O1 Biovar El Tor Strains with Different Structure of Anti-Phage Systems
Journal: Problems of Particularly Dangerous Infections
Year: 2025

The aim of the work was to study the presence of anti-phage systems in the genome of non-toxigenic Vibrio cholerae O1 biovar El Tor strains and to determine the resistance of strains with different structures of these systems to the cholera diagnostic bacteriophage El Tor. Materials and methods . The work used 126 non-toxigenic (ctxA– tcpA+ and ctxA – tcpA – ) strains of V. cholerae O1 El Tor, isolated from the external environment and from patients with acute intestinal infections in the territ