PHENOTYPIC COMPOSITION OF TUMOR CELLS AND THEIR ROLE IN THE PROCESS OF METASTASIS WHEN DEVELOPING A PDX MODEL OF BREAST CANCER
Journal: Cardiometry
Year: 2023

To study the mechanisms of metastasis, one of the effective tools is mouse models using primary patient tumors (Patient-Derived Xenograft, PDX). The phenomenon of changes in the cell phenotype in response to the dynamic conditions of the tumor microenvironment is one of the key processes forming the basis for metastasis.