The Frequency of Allele CCR5∆32 in a Serbian Population / UČESTALOST ALELA CCR5∆32 U SRPSKOJ POPULACIJI
Journal: Journal of Medical Biochemistry
Year: 2013

Summary Background: The mutant CCR5Δ32 allele confers resist- ance to HIV infection. Several hypotheses regarding its ori- gin and persistence in the human population have been proposed. It is assumed that the Δ32 mutation was intro- duced in Northern or Eastern Europe and that it spread to the south. Although the frequency of CCR5Δ32 was deter- mined in numerous European nations and regions, further data are needed to complete the puzzle of CCR5Δ32 dis- tribution within the continent. Methods: