Gamma-glutamyltransferase to Determine Cardiovascular Risk: Shifting the Paradigm Forward
Journal: Journal of Atherosclerosis and Thrombosis
Year: 2011

Gamma-glutamyltransferase (GGT), regarded as a marker of excessive alcohol consumption or liver disturbances, is an enzyme catalyzing the first step in the extracellular degradation of the antioxidant glutathione (GSH) and may take part in atherogenesis. The marked relationship between GGT and the atherosclerotic process has shifted attention to the issue of whether its serum levels can aid in the detection of individuals at high risk for incident cardiovascular events. It is likely that the pro