Association of polymorphism of C159T gene of receptor CD14 and antiendotoxin immunity in patients with refractory / corticosteroids-sensitive asthma
Journal: SHILAP Revista de lepidopterología
Year: 2020

Introduction. Therefractory asthma refers to the phenotype, which is characterized by severe persistent course with frequent exacerbations and resistance to corticosteroid therapy. This phenotype of asthma can be related to C159T polymorphism of CD14 receptor gene Material and methods.There were studied the C159T polymorphism of CD14 gene in 331 patients with bronchial asthma. The control group consisted of 285 healthy individuals of Crimea. The C159T gene polymorphism of CD14 was detected by al