BIOLOGIC MARKERS OF FIBROGENESIS IN PULMONARY SARCOIDOSIS PATIENTS
Journal: The Bulletin of Contemporary Clinical Medicine
Year: 2024

Introduction. Sarcoidosis-associated pulmonary ﬁbrosis still lacks biomarkers to predict progression. Whole-genome association studies and other genetic research over the past few years have identiﬁed several single nucleotide polymorphisms that are associated with an increased risk of developing pulmonary ﬁ brosis. In sarcoidosis, relatively reliable predictors of the disease activity include serum angiotensin-converting enzyme, soluble interleukin-2 receptor (sIL-2R) and chitotriosidase. Level