Relationship between leptin levels and systemic inflammation indices in overweight male patients with generalized periodontitis
Journal: Russian Journal of Geriatric Medicine
Year: 2025

BACKGROUND . Activation of inflammation in the periodontium is inextricably linked with systemic processes in the body, accompanied by an inflammatory response. One of these conditions is excess body weight, which in most cases is accompanied by the development of insulin resistance and hyperleptinemia. The adipose tissue hormone leptin, in conditions of insulin resistance, promotes the activation of inflammation, changes in cytokine regulation. OBJECTIVE . To study the relationship between the