Impact of Aging and Pathologies on Human Oral Mucosa: Preliminary Investigation of Biophysical Markers from Thermal and Vibrational Analyses
Journal: Biomolecules
Year: 2025

This study first examines the potential of using Fourier-transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) to extract molecular and organizational markers from human oral mucosa. These indicators are then examined in relation to age and pathophysiological conditions. Oral mucosa biopsies were collected from 38 patients during surgical procedures and analyzed using FTIR and DSC-validated protocols. The patients were divided into two age groups, namely 20-40 and 70