PRODUCTION AND LARGE-SCALE EXPANSION OF FUNCTIONALLY ACTIVE NK CELLS SUITABLE FOR USE IN IMMUNOTHERAPY OF HEMATOLOGICAL AND SOLID TUMORS
Journal: Cardiometry
Year: 2022

Natural killer cells (NK) are part of the innate immune system of the body and play an important role in the immune surveillance of foreign cells and the body’s own altered cells, including the transformed ones. The NK cells, without prior stimulation, can eliminate target cells which do not express their own MHC class I molecules or express stress-induced molecules. These basic, natural functions of the NK cells as a tool in the fight against malignant tumors have attracted particular attention