Serum adiponectin is positively associated with lung function in young adults, independent of obesity: The CARDIA study
Journal: Respiratory Research
Year: 2010

Adipose tissue produces adiponectin, an anti-inflammatory protein. Adiponectin deficiency in mice is associated with abnormal post-natal alveolar development. We hypothesized that lower serum adiponectin concentrations are associated with lower lung function in humans, independent of obesity. We explored mediation of this association by insulin resistance and systemic inflammation. Spirometry testing was conducted at years 10 and 20 follow-up evaluation visits in 2,056 eligible young adult parti