CUAD (Contact Unmodified Antisense DNA) Biotechnology: List of Pest Species Successfully Targeted by Oligonucleotide Insecticides
Journal: Preprints.org
Year: 2024

The idea of CUAD (contact unmodified antisense DNA) biotechnology and the use of oligonucleotide insecticides (briefly, olinscides, or DNA insecticides) was proposed on lepidopterans and gradually disseminated on hemipteran pests. As the next-generation platform for creation of insecticides, it has a number of unique characteristics (short unmodified antisense DNA as contact insecticide, insect rRNAs as target, DNA containment as mechanism of action) that distinguish it from existing classes of