Pharmacological Effects of Atorvastatin in Platelet Function and Plaque Rupture
Journal: Journal of Applied Pharmaceutical Science
Year: 2016

Platelets are a prime reason for causing cardiovascular disease (CVD). After atherosclerotic plaque rupture, platelets can form pathogenic, formation of blood clot which leads to various cardiovascular events. The beneficial effect of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-Co-A) reductase inhibitors reduces CVDs clinically. The objective of this review is the pharmacological benefit of atorvastatin in CVD by platelets and plaque rupture due to high levels of cholesterol.