THE EFFECT PRODUCED BY IL-2 AND IL-15 ON THE PROLIFERATION OF T CELLS IN VITRO IN PATIENTS DIAGNOSED WITH BREAST CANCER
Journal: Cardiometry
Year: 2023

Over the past decade, the use of adoptive immunotherapy has emerged as a promising approach to treatment of various malignancies, including breast cancer. Cytokines are involved in the development, differentiation and homeostasis of the T cells. Despite the similarities in signaling pathways, the γc cytokines shape the T cell responses differently: IL-2 plays a major role in the development and maintenance of the regulatory T cells, while IL15 stimulates the proliferation and cytotoxic functions