Crimean–Congo Hemorrhagic Fever Virus: Progress in Vaccine Development
Journal: Diagnostics
Year: 2023

Crimean-Congo hemorrhagic fever virus (CCHFV), a member of the <i>Nairoviridae</i> family and <i>Bunyavirales</i> order, is transmitted to humans via tick bites or contact with the blood of infected animals. It can cause severe symptoms, including hemorrhagic fever, with a mortality rate between 5 to 30%. CCHFV is classified as a high-priority pathogen by the World Health Organization (WHO) due to its high fatality rate and the absence of effective medical countermeasures. CCHFV is endemic in se