Crimean-Congo Hemorrhagic Fever
Year: 2019

Crimean hemorrhagic fever (CHF) was described as a clinical entity in 1944 and 1945 during an epidemic in the western steppe region of Crimea, U.S.S.R. A viral etiology was suggested by reproducing a similar disease syndrome in psychiatric patients undergoing pyrogenic therapy after inoculation with a filterable agent from the blood of CHF patients. CHF virus was shown to be antigenically indistinguishable from Congo virus,originally isolated in 1956 from a febrile patient in Belgian Congo. An e