Cytochrome <i>c</i> as a facultative enzyme – lipoperoxidase and it’s inhibition by antioxidants
Journal: bioRxiv (Cold Spring Harbor Laboratory)
Year: 2019

Abstract Many researchers consider a key role in initiation of apoptosis along the mitochondrial pathway to be enhanced by cytochrome c, one of the components of the mitochondrial respiratory chain, which acquires peroxidase activity by forming a complex with phospholipids. Mitochondrial membranes are destroyed affected by the peroxidase reaction catalyzed by this supramolecular nanoparticle, resulting in the release of various proapoptotic factors into the cellular cytoplasm, ultimately leading