Relationship of Adropin Level and Inducible Nitric Oxide Synthase with the Phases of Intestinal Ischemia-Reperfusion in Rats
Journal: The Medical Journal of Cairo University/The Medical Journal of Cairo University
Year: 2018

Background: Adropin is a peptide hormone that plays an important role in energy homeostasis and endothelial functions. Nitric oxide is a potent vasodilator synthesized in the vascular endothelium from the Nitric Oxide Synthase enzyme (NOS). There are controversial studies about the role of NOS and its isoforms the endothelial (eNOS) and the inducible (iNOS) forms in Ischemia-Reperfusion (IR) injury. It was found that adropin influences gene expression of eNOS and enhances endothelial cell functi