Is serum apelin related to portal hemodynamics in patients with liver cirrhosis?
Journal: The Egyptian Journal of Internal Medicine
Year: 2018

Apelin is the endogenous ligand of the angiotensin-like receptor. The expression of apelin–APJ (apelin receptor) signaling is associated with the development of portal hypertension (PH) and contributes toward the formation of Porto systemic collaterals and splanchnic neovascularization in PH. We aimed to study the relationship between apelin and portal hemodynamics in cirrhotic patients. Thus study included 60 cirrhotic patients from Menoufia University Hospitals (Egypt) and 20 healthy volunteer