Effect of Cryopreservation on Functional Status of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Animals with Autoimmune Pathology
Journal: Problems of Cryobiology and Cryomedicine
Year: 2016

The application of cryopreserved autologous bone marrow (BM) is the reconstructive therapy tool for autoimmune diseases (AIDs). The BM use efficiency is determined by preservation rate of its hematopoietic and mesenchymal stem cells (HSCs and MSCs, respectively). This fact determines the need to design the optimal cryopreservation regimens for the BM of AIDs donors. Here we assessed a functional status of bone marrow HSCs and MSCs of mice with adjuvant arthritis (AA), initiated by Freund's compl