Optimization of microwave-assisted extraction to maximize phenolic content and antioxidant capacity of Salvia tomentosa using response surface methodology
Journal: Mediterranean veterinary journal.
Year: 2025

Objective of this study was to optimise microwave-assisted extraction for maximizing the recovery of Salvia tomentosa polyphenols and antioxidant compounds by using Response Surface Methodology (RSM). A three-level trivariate Box-Behnken design (BBD) was used to optimize the total phenolic content (TPC) and antioxidant activity (DPPH) by microwave-assisted extraction (MAE) method Extraction time (1-3 minutes, X1), solvent-to-solid ratio (20-40 ml/g, X2), and microwave power (100-800 watts, X3) w