Computational Repurposing of FDA Approved Drugs Against Monkeypox Virus Cysteine Proteinase: A Molecular Docking and Dynamics Simulation Study.
Year: 2022

Monkeypox is a zoonotic disease caused by a DNA virus known as Monkeypox virus. Generally, Monkeypox disease is considered a self-limiting condition with symptoms similar to that of smallpox disease. Most cases of Monkeypox are considered mild but some patients may suffer from serious complications. Due to the high similarity between Monkeypox virus and smallpox virus, therefore vaccines and antiviral therapies originally intended for use against smallpox can be effective also in Monkeypox infec