Evaluation of the effectiveness of eradication therapy using cytochrome P450 2C19 genotyping
Journal: Clinical Medicine (Russian Journal)
Year: 2026

Relevance . Infection with Helicobacter pylori (НР), a class 1 carcinogen for gastric cancer development, is steadily increasing in the world population and reaches 50%. Currently, eradication therapy (ET) is considered the most relevant strategy for the prevention of gastric cancer. Due to the low eradication rates when using a triple regimen based on clarithromycin, the addition of bismuth salts and the use of double doses of proton pump inhibitors are recommended. Objective . To evaluate the