Computational modeling of drug-eluting balloons in peripheral artery disease: Mechanisms, optimization, and translational insights
Journal: Computational and Structural Biotechnology Journal
Year: 2025

Drug-eluting balloons (DEBs) represent a promising alternative to stent-based interventions for peripheral artery disease (PAD), and their therapeutic efficacy is dependent on optimizing drug transfer, mechanical deployment, and vessel-wall interactions. This review synthesizes current advancements in computational modeling; systematically analyzes studies identified through comprehensive ScienceDirect, Scopus, and PubMed (2015-2025) searches; and selects them according to PRISMA guidelines. Key