Nanoscale Enhancement of Photosensitized Radionuclide Stimulated Therapy
Journal: Open Scholarship Institutional Repository (Washington University in St. Louis)
Year: 2021

Photodynamic therapy (PDT) provides efficient tumor killing through the generation of reactive oxygen species (ROS) from the optical excitation of a photosensitizer (PS). Furthermore, this mechanism is highly immune stimulating, providing systemic tumor immunity with a reduction in metastasis. However, these materials had previously been limited by their dependence upon external light sources, allowing treatment of only laser-accessible malignancy. With the recent development of photosensitized