Effect of oxidized dextran on rat hepatocytes in toxic hepatosis of mixed etiology
Journal: Сибирский научный медицинский журнал
Year: 2021

The aim of research was to study the oxidized dextran protection effect against hepatic parenchyma defect at combinated acute and chronic toxicity of ethyl alcohol and tetrachloromethane solutions. Materials and methods. 150 male Wistar rats were injected by toxicants with intraperitoneal administration: 50 % CCl 4 in olive oil solution and 5 % oxidized dextran (OD) aqueous solution with molecular weight 40 kDa and peroral 6.5 % ethyl alcohol aqueous solution. Tetrachloromethane was injected onc