THE ROLE OF THE SYSTEM OF INSULIN-LIKE GROWTH FACTORS IN BLOOD IN SOFT TISSUE SARCOMAS
Journal: Cardiometry
Year: 2022

Although soft tissue sarcomas (STS) belong to a group of rare diseases of mesenchymal origin, their characteristic tendency to recurrence and high mortality necessitates the search for some prognostic bio-markers to identify patients at risk of their recurrence [1]. In this regard, the system of insulinlike growth factors (IGF) and their binding proteins (IGFBP) is of interest, since it has been established that dysregulation of the IGF system leads to the proliferation of cancer cells, migratio