THE INFLUENCE OF HUMORAL IMMUNITY ANTIENDOTOXIN RESPONSE TO INDICATORS OF SYSTEMIC INFLAMMATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Journal: Russian Journal of Infection and Immunity
Year: 2016

Introduction. Systemic lupus erythematosus (SLE) — severe autoimmune disease that has a high level of morbidity and mortality. With each decade the SLE incidence rate grows up. Current researches do not allow to identify the etiology of this disease. The polyclonal stimulation of T and B lymphocytes processes are prevailed in pathogenetic picture of the disease. One of the most powerful triggers of stimulation may be a gram-negative bacteria lipopolysaccharide (LPS) or endotoxin (ET). The impact