Zebrafish as a Model Organism for Research in Rare Genetic Neuromuscular Diseases
Journal: International Journal of Molecular Sciences
Year: 2025

The zebrafish (<i>Danio rerio</i>) has become one of the most popular and valuable model organisms for studying rare neuromuscular diseases. Its unique characteristics, including the high number of offspring produced with each mating, transparent eggs, rapid development, and genetic similarity to humans, make this small vertebrate ideal for investigating complex and rare disorders affecting the skeletal muscle, such as Duchenne Muscular Dystrophy (DMD), Limb Girdle Muscular Dystrophies (LGMDs),