GABAergic Mechanisms of the Brain Tolerance to Hypoxia in Lower Vertebrates
Journal: Российский физиологический журнал им  И  М  Сеченова
Year: 2023

Hypoxic/ischemic brain injuries a major medical challenge. One of the approaches to the development of therapeutic interventions is to establish the pathways of survival for neurons in tolerant to O2 deficiency vertebrates, which could suggest the ways to mitigate hypoxic catastrophe for separate cells under oxygen starvation. Metabolic depression is considered to be a universal strategy for the survival of hypoxia tolerant animals; however, the details of the mechanism of brain metabolism limit