Drug Repurposing with Tetracycline and Kampo Medicine (Sho-Sai-Koto and Saiko-Keishi-to) for Crimean-Congo Hemorrhagic Fever: Predicting Efficacy Through In Silico Studies
Journal: Preprints.org
Year: 2025

The Crimean-Congo hemorrhagic fever virus is a tick-borne bunyavirus that leads to acute febrile illness with myalgia, dizziness, neck pain and headache and a high mortality rate in humans. Currently, no specific antiviral drugs have been approved for treatment, making the search for effective drugs against this virus and the execution of clinical trials a significant concern. Drug repurposing is a well-established strategy for redeploying existing licensed drugs for newer indications, facilitat