THE ROLE OF GASOTRANSMITTERS IN REGULATING OF THE FUNCTIONS OF SMOOTH MUSCLES: THE POSSIBLE EFFECTOR SYSTEMS
Journal: Bulletin of Siberian Medicine
Year: 2014

Influence of gasotransmitters carbon monoxide (CO) and hydrogen sulfide (H 2 S) on the electrical and contractile activities of smooth muscle cells (SMCs) of the guinea pig ureter and rat aorta were studied by methods of double sucrose bridge and mechanography. It has been shown that CO causes a dose-dependent decrease of the contractile response of SMCs of the ureter and rat aorta and also reduces the amplitude and duration of the action potential plateau. Against the background of the action o