Effects of Beta-Carboline Alkaloids of Peganum Harmala on Induced Rat Ileum Contractions
Journal: Pharmacognosy Journal
Year: 2020

Peganum harmala L., Zygophyllaceae popularly known as Wild Syrian rue, a well-known plant in folk medicine for many pharmacological uses including antispasmodic activity. Chemical composition of the plant showed that the most important constituents of this plant are betacarboline alkaloids such as harmalol, harmaline, and harmine. In this work, we aimed to evaluate the effects of these three major harmala alkaloids on induced rat ileum contractions, induced by acetylcholine, BaCl 2 and KCl. Of t