Role of lipopolysaccharide in genesis of microvascular complications in type 1 diabetes mellitus
Journal: Medical Immunology (Russia)
Year: 2023

Despite significant advances in pathogenetic treatments for patients with diabetes mellitus type 1 (DM1) and reduction of mortality in this cohort of patients, as compared with general population, the difference in life expectancy in DM1 patients at the age of 20 years is about 10-12 years. Microvascular complications that increase the risk of cardiovascular disease (CVD) and overall mortality represent one of the most important problems in management of patients with DM1. The excessive risks pe