BRCA GENES MUTATIONS’ OF HEREDITARY BREAST CANCER IN CRIMEA
Journal: Voprosy Onkologii
Year: 2020

Introduction. The hereditary predisposition to the growth of breast cancer (BC), associated with germline mutations of DNA genes repair (BRCA(1,2)), is characterized by a variety of polymorphism variants, with a tendency to a certain specificity in different population groups. In regions with a mixed population composition, such as Crimean Peninsula, the problem of the relationship of specific mutations and a population group is not only of scientific interest, but also has rather important prac