Leptin and curcumin affect renal ischemia-reperfusion injury via modulation of P65 and Bax genes expression
Journal: The Ukrainian Biochemical Journal
Year: 2021

Ischemia and reperfusion are natural steps during kidney transplantation, and ischemia-reperfusion injury is a critical condition in which physicians must preserve organ function and control cell damage. As leptin is thought to play an important role in the regulation of the immune system and inflammation and curcumin is a potent anti-fibrotic agent, both agents are promising to have therapeutic impact on renal damage. The present study was designed to evaluate the effects of leptin and curcumin