IMPACT OF THE SINGLE-NUCLEOTIDE POLYMORPHISM OF GENES IL1β, EDN1, AND NOS3 GENES ON THE INDIVIDUAL GENETIC PROFILE OF PATIENTS WITH CORONARY HEART DISEASE IN THE REPUBLIC OF CRIMEA
Journal: The Bulletin of Contemporary Clinical Medicine
Year: 2023

Abstracts. Introduction. Coronary heart disease prevalence rate grows, which determines the importance of researchers’ inquiries aiming to improve the prevention, diagnosis, and treatment of this pathology. Aim. This study was aimed at identifying the associations of polymorphisms of genes interleukin 1-beta, endothelin-1, and endothelial nitric oxide synthase in patients with coronary heart disease. Materials and Methods. We studied polymorphic markers of endothelin-1 (rs5370), endothelial nitr