Sebaceous gland - wikipedia Sebaceous gland Sebaceous gland Schematic view of hair follicle and sebaceous gland. Cross-section of all skin layers. A hair follicle with associated structures. ( Sebaceous glands labeled at center left. ) Details Identifiers Latin glandula sebacea MeSH D012627 TA A16. 0.00. 03 FMA 59160 Anatomical terminology ( edit on Wikidata ) Sebaceous glands are microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals. In humans, they occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. The type of secretion of the sebaceous glands is referred to as holocrine. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Fordyce spots are ectopic ( misplaced ) sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Areolar glands surround the female nipples. Several related medical conditions involve sebum -- including acne, sebaceous cysts, hyperplasia, and sebaceous adenoma. These are usually attributable to overactive sebaceous glands, which produce excess sebum. Contents 1 Structure 1.1 Location 1.2 Development 2 Function 2.1 Sebum 2.2 Immune function and nutrition 2.3 Unique sebaceous glands 3 Clinical significance 3.1 Acne 3.2 Other 4 History 5 Other animals 6 See also 7 References 8 External links Structure Location The sebaceous glands are found throughout all areas of the skin except the palms of the hands and soles of the feet. There are two types of sebaceous gland, those connected to hair follicles, in pilosebaceous units, and those that exist independently. Sebaceous glands are found in hair - covered areas, where they are connected to hair follicles. One or more glands may surround each hair follicle, and the glands themselves are surrounded by arrector pili muscles. The glands have an acinar structure ( like a many - lobed berry ), in which multiple glands branch off a central duct. Relative to keratinocytes that make up the hair follicle, sebaceous glands are composed of huge cells with many large vesicles that contain the sebum. These cells express Na and Cl ion channels, ENaC and CFTR ( see Fig. 6 and Fig. 7 in reference ). The glands deposit sebum on the hairs, and bring it to the skin surface along the hair shaft. The structure consisting of hair, hair follicle, arrector pili muscles, and sebaceous gland is an epidermal invagination known as a pilosebaceous unit. Sebaceous glands are also found in hairless areas ( glabrous skin ) of the eyelids, nose, penis, labia minora, the inner mucosal membrane of the cheek, and nipples. Some sebaceous glands have unique names. Sebaceous glands on the lip and mucosa of the cheek, and on the genitalia, are known as Fordyce spots, and glands on the eyelids are known as meibomian glands. Sebaceous glands of the breast are also known as Montgomery 's glands. Development Sebaceous glands are first visible from the 13th to the 16th week of fetal development, as bulgings off hair follicles. Sebaceous glands develop from the same tissue that gives rise to the epidermis of the skin. Overexpression of the signalling factors Wnt, Myc and SHH all increase the likelihood of sebaceous gland presence. The sebaceous glands of a human fetus secrete a substance called vernix caseosa, a waxy, translucent white substance coating the skin of newborns. After birth, activity of the glands decreases until there is almost no activity during ages 2 -- 6 years, and then increases to a peak of activity during puberty, due to heightened levels of androgens. Base of pilosebaceous unit Insertion of sebaceous glands into hair shaft Sagittal section through the upper eyelid. A hair follicle with associated structures. Scalp cross section showing follicle with sebaceous glands. Function Sebaceous glands secrete the oily, waxy substance called sebum ( Latin : fat, tallow ) that is made of triglycerides, wax esters, squalene, and metabolites of fat - producing cells. Sebum waterproofs and lubricates the skin and hair of mammals. Sebaceous secretions in conjunction with apocrine glands also play an important thermoregulatory role. In hot conditions, the secretions emulsify the sweat produced by the eccrine glands and this produces a sheet of sweat that is not readily lost in drops of sweat. This is of importance in delaying dehydration. In colder conditions, the nature of sebum becomes more lipid and in coating the hair and skin, rain is effectively repelled. Sebum is produced in a holocrine process, in which cells within the sebaceous gland rupture and disintegrate as they release the sebum and the cell remnants are secreted together with the sebum. The cells are constantly replaced by mitosis at the base of the duct. Sebum Sebum, secreted by the sebaceous gland in humans, is primarily composed of triglycerides ( ≈ 41 % ), wax esters ( ≈ 26 % ), squalene ( ≈ 12 % ), and free fatty acids ( ≈ 16 % ). The composition of sebum varies across species. Wax esters and squalene are unique to sebum and not produced as final products anywhere else in the body. Sapienic acid is a sebum fatty acid that is unique to humans, and is implicated in the development of acne. Sebum is odorless, but its breakdown by bacteria can produce strong odors. Sex steroids are known to affect the rate of sebum secretion ; androgens such as testosterone have been shown to stimulate secretion, and estrogens have been shown to inhibit secretion. Dihydrotestosterone acts as the primary androgen in the prostate and in hair follicles. Immune function and nutrition Sebaceous glands are part of the body 's integumentary system and serve to protect the body against germs. Sebaceous glands secrete acids that form the acid mantle. This is a very fine, slightly acidic film on the surface of the skin that acts as a barrier to bacteria, viruses, and other potential contaminants that might penetrate the skin. The pH of the skin is between 4.5 and 6.2, and this acidity helps to neutralise the primarily alkaline nature of contaminants. Sebaceous lipids make an important contribution in maintaining the integrity of the skin barrier, and express both pro-inflammatory and anti-inflammatory properties. Sebum may act as a delivery system for antioxidants, antimicrobial lipids, pheromones, and hydration of the stratum corneum. The insoluble fatty acids contained within sebum have broad antimicrobial activity. Additionally, sebaceous gland secretion provides vitamin E to the upper layers of facial skin. Unique sebaceous glands During the last three months of fetal development, the sebaceous glands of the fetus produce vernix caseosa, a waxy white substance that coats the skin to protect it from amniotic fluid. The areolar glands are in the areola that surrounds the nipple in the female breast. These glands secrete an oily fluid that lubricates the nipple, and also secrete volatile compounds that are thought to serve as an olfactory stimulus for the newborn. During pregnancy and lactation these glands, also called Montgomery 's glands, become enlarged. Meibomian glands, in the eyelids, secrete a form of sebum called meibum onto the eye, that slows the evaporation of tears. It also serves to create an airtight seal when the eyes are closed and its lipid quality also prevents the eyelids from sticking together. The meibomian glands are also known as tarsal glands, Zeis glands and palpebral glands. They attach directly to the follicles of the eyelashes, which are arranged vertically within the tarsal plates of the eyelids. Fordyce spots, or Fordyce granules, are ectopic sebaceous glands found on the genitals and oral mucosa. They show themselves as yellowish - white milia ( milk spots ). Earwax is partly composed of sebum produced by glands in the ear canal. These secretions are viscous and have a high lipid content, which provides good lubrication. Clinical significance Conditions of sebaceous glands. Sebaceous glands are involved in skin problems such as acne and keratosis pilaris. In the skin pores, sebum and keratin can create a hyperkeratotic plug called a comedo. Acne Main article : Acne Acne is a very common problem, particularly during puberty in teenagers, and is thought to relate to an increased production of sebum due to hormonal factors. The increased production of sebum can lead to a blockage of the sebaceous gland duct. This can cause a comedo, ( commonly called a blackhead or a whitehead ), which can lead to infection, particularly by the bacteria Propionibacterium acnes. This can inflame the comedones, which then change into the characteristic acne lesions. Comedones generally occur on the areas with more sebaceous glands, particularly the face, shoulders, upper chest and back. Comedones may be ' black ' or ' white ' depending on whether the entire pilosebaceous unit, or just the sebaceous duct, is blocked. Sebaceous filaments -- innocuous build - ups of sebum -- are often mistaken for whiteheads. There are many treatments available for acne from reducing sugars in the diet, to medications that include antibiotics, benzoyl peroxide, retinoids and hormonal treatments. Retinoids reduce the amount of sebum produced by the sebaceous glands. Should the usual treatments fail, the presence of the Demodex mite could be looked for as the possible cause. Other Other conditions that involve the sebaceous glands include : Seborrhoea refers to overactive sebaceous glands, a cause of oily skin or hair. Sebaceous hyperplasia, referring to excessive proliferation of the cells within the glands, and visible macroscopically as small papules on the skin, particularly on the forehead, nose and cheeks. Seborrhoeic dermatitis, a chronic, usually mild form of dermatitis effected by changes in the sebaceous glands. In newborn infants seborrhoea dermatitis can occur as cradle cap. Seborrheic - like psoriasis ( also known as `` Sebopsoriasis '', and `` Seborrhiasis '' ) is a skin condition characterized by psoriasis with an overlapping seborrheic dermatitis. Sebaceous adenoma, a benign slow - growing tumour -- which may, however, in rare cases be a precursor to a cancer syndrome known as Muir -- Torre syndrome. Sebaceous carcinoma, an uncommon and aggressive cutaneous tumour. Sebaceous cyst is a term used to refer to both an epidermoid cyst and a pilar cyst, though neither of these contain sebum, only keratin and do not originate in the sebaceous gland and so are not true sebaceous cysts. A true sebaceous cyst is relatively rare and is known as a steatocystoma. Phymatous rosacea is a cutaneous condition characterized by an overgrowth of sebaceous glands. History The word sebaceous, meaning `` consisting of sebum '', was first termed in 1728 and comes from the Latin for tallow. Sebaceous glands have been documented since at least 1746 by Jean Astruc, who defined them as ``... the glands which separate the fat. '' He describes them in the oral cavity, on the head, eyelids and ears, as `` universally '' acknowledged., viii Astruc describes them being blocked by `` small animals '' that are `` implanted '' in the excretory ducts, and attributes their presence in the oral cavity to apthous ulcers, noting `` these glands naturally ( secrete ) a viscous humour, which puts on various colours and consistencies... in its natural state is very mild, balsamic, and intended to wet and lubricate the mouth '' In The Principles of Physiology 1834, Andrew Combe noted that the glands were not present in the palms of the hands or soles of the feet. Other animals Example of a gular gland in a male black bonneted bat The preputial glands of mice and rats are large modified sebaceous glands that produce pheromones used for territorial marking. These and the scent glands in the flanks of hamsters have a similar composition to human sebaceous glands, are androgen responsive, and have been used as a basis for study. Some species of bat, including the Mexican free - tailed, have a specialized sebaceous gland occurring on the throat called a `` gular gland ''. This gland is present more frequently in males than females, and it is hypothesized that the secretions of the gland are used for scent - marking. Sebaceous adenitis is an autoimmune disease that affects sebaceous glands. It is mainly known to occur in dogs, particularly poodles and akitas, where it is thought to be generally autosomal recessively inherited. It has also been described in cats, and one report describes this condition in a rabbit. In these animals, it causes hair loss, though the nature and distribution of the hair loss differs greatly. See also List of glands of the human body Nasal sebum Sebaceous filament References ^ Jump up to : James, William D. ; Berger, Timothy ; Elston, Dirk M. ( 2006 ). Andrews ' Diseases of the Skin : Clinical dermatology. Saunders Elsevier. p. 7. ISBN 978 - 0 - 7216 - 2921 - 6. ^ Jump up to : Young, Barbra ; Lowe, James S ; Stevens, Alan ; Heath, John W ; Deakin, Philip J ( March 2006 ). Wheater 's Functional Histology ( 5 ed. ). Elsevier Health Sciences. pp. 175 -- 178. ISBN 978 - 0 - 443 - 06850 - 8. ^ Jump up to : Hanukoglu I, Boggula VR, Vaknine H, Sharma S, Kleyman T, Hanukoglu A ( January 2017 ). `` Expression of epithelial sodium channel ( ENaC ) and CFTR in the human epidermis and epidermal appendages ''. Histochemistry and Cell Biology. 147 ( 6 ) : 733 -- 748. doi : 10.1007 / s00418 - 016 - 1535 - 3. PMID 28130590. ^ Jump up to : Smith, K.R. ; Thiboutot, D.M. ( 2007 ). `` Thematic Review Series : Skin Lipids. Sebaceous Gland Lipids : Friend Or Foe ? ''. Journal of Lipid Research. 49 ( 2 ) : 271 -- 281. doi : 10.1194 / jlr. R700015 - JLR200. PMID 17975220. ^ Jump up to : Thiboutot, D ( July 2004 ). `` Regulation of human sebaceous glands ''. The Journal of Investigative Dermatology. 123 ( 1 ) : 1 -- 12. doi : 10.1111 / j. 1523 - 1747.2004. t01 - 2 -. x. PMID 15191536. ^ Jump up to : Thody, A.J. ; Shuster, S. ( 1989 ). `` Control and Function of Sebaceous Glands ''. Physiological Reviews. 69 ( 2 ) : 383 -- 416. PMID 2648418. Jump up ^ Dellmann 's textbook of veterinary histology ( 405 pages ), Jo Ann Coers Eurell, Brian L. Frappier, 2006, p. 29, weblink : Books - Google - RTOC. ^ Jump up to : Zouboulis, C.C. ( 2004 ). `` Acne and Sebaceous Gland Function ''. Clinics in Dermatology. 22 ( 5 ) : 360 -- 366. doi : 10.1016 / j. clindermatol. 2004.03. 004. PMID 15556719. Jump up ^ Porter AM ( 2001 ). `` Why do we have apocrine and sebaceous glands ? ''. JR Soc Med. 94 ( 5 ) : 236 -- 7. PMC 1281456. PMID 11385091. Jump up ^ Victor Eroschenko, diFiore 's Atlas of Histology with functional correlations, Lippincott Williams & Wilkins, 10th edition, 2005. p. 41 Jump up ^ Dorland 's ( 2012 ). Dorland 's Illustrated Medical Dictionary ( 32nd ed. ). Elsevier Saunders. p. 866. ISBN 978 - 0 - 19 - 856878 - 0. ^ Jump up to : Cheng JB, Russell DW ; Russell ( September 2004 ). `` Mammalian Wax Biosynthesis II : Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family '' ( PDF ). The Journal of Biological Chemistry. 279 ( 36 ) : 37798 -- 807. doi : 10.1074 / jbc. M406226200. PMC 2743083. PMID 15220349. Jump up ^ Webster, Guy F. ; Anthony V. Rawlings ( 2007 ). Acne and Its Therapy. Basic and clinical dermatology. 40. CRC Press. p. 311. ISBN 0 - 8247 - 2971 - 4. ^ Jump up to : Draelos, Zoe Diana ( 2005 ). Hair care : an illustrated dermatologic handbook. London ; New York : Taylor & Francis. p. 26. ISBN 978 - 1 - 84184 - 194 - 6. Jump up ^ Sweeney, Thomas M ( December 1968 ). `` The Effect of Estrogen and Androgen on the Sebaceous Gland Turnover Time ''. The Journal of Investigative Dermatology. 53 : 8 -- 10. doi : 10.1038 / jid. 1969.100. Jump up ^ Amory JK, Anawalt BD, Matsumoto AM, Page ST, Bremner WJ, Wang C, Swerdloff RS, Clark RV ( June 2008 ). `` The effect of 5alpha - reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men ''. J. Urol. 179 ( 6 ) : 2333 -- 8. doi : 10.1016 / j. juro. 2008.01. 145. PMC 2684818. PMID 18423697. Jump up ^ Wilkinson, P.F. Millington, R. ( 1983 ). Skin ( Digitally printed version ed. ). Cambridge ( GB ) ( etc. ) : Cambridge university press. p. 151. ISBN 978 - 0 - 521 - 24122 - 9. Jump up ^ Monika - Hildegard Schmid - Wendtner ; Korting Schmid - Wendtner ( 2007 ). Ph and Skin Care. ABW Wissenschaftsverlag. pp. 31 --. ISBN 978 - 3 - 936072 - 64 - 8. Retrieved 19 June 2012. Jump up ^ Zlotogorski A ( 1987 ). `` Distribution of skin surface pH on the forehead and cheek of adults ''. Arch. Dermatol. Res. 279 ( 6 ) : 398 -- 401. doi : 10.1007 / bf00412626. PMID 3674963. Jump up ^ Schmid MH, Korting HC ( 1995 ). `` The concept of the acid mantle of the skin : its relevance for the choice of skin cleansers '' ( PDF ). Dermatology. 191 ( 4 ) : 276 -- 80. doi : 10.1159 / 000246568. PMID 8573921. Archived from the original ( PDF ) on 1 March 2011. Jump up ^ Youn, S.W. ( 2010 ). `` The Role of Facial Sebum Secretion in Acne Pathogenesis : Facts and Controversies ''. Clinics in Dermatology. 28 ( 1 ) : 8 -- 11. doi : 10.1016 / j. clindermatol. 2009.03. 011. PMID 20082943. ^ Jump up to : Mackenna, R.M.B. ; Wheatley, V.R. ; Wormall, A. ( 1950 ). `` The Composition of the Surface Skin Fat ( ' Sebum ' ) from the Human Forearm ''. Journal of Investigative Dermatology. 15 ( 1 ) : 33 -- 47. doi : 10.1038 / jid. 1950.69. PMID 14774573. Jump up ^ `` Thematic Review Series : Skin Lipids. Antimicrobial lipids at the skin surface ''. 10 May 2011. Jump up ^ Thiele, Jens J. ; Weber, Stefan U. ; Packer, Lester ( 1999 ). `` Sebaceous Gland Secretion is a Major Physiologic Route of Vitamin E Delivery to Skin ''. Journal of Investigative Dermatology. 113 ( 6 ) : 1006 -- 1010. doi : 10.1046 / j. 1523 - 1747.1999. 00794. x. PMID 10594744. Jump up ^ Zouboulis, Christos C. ; et al., Jens Malte ; et al. ( 2008 ). `` Frontiers in Sebaceous Gland Biology and Pathology ''. Experimental Dermatology. 17 ( 6 ) : 542 -- 551. doi : 10.1111 / j. 1600 - 0625.2008. 00725. x. PMID 18474083. Jump up ^ Doucet, Sébastien ; Soussignan, Robert ; Sagot, Paul ; Schaal, Benoist ( 2009 ). Hausberger, Martine, ed. `` The Secretion of Areolar ( Montgomery 's ) Glands from Lactating Women Elicits Selective, Unconditional Responses in Neonates ''. PLoS ONE. 4 ( 10 ) : e7579. doi : 10.1371 / journal. pone. 0007579. PMC 2761488. PMID 19851461. Jump up ^ McCulley, JP ; Shine, WE ( March 2004 ). `` The lipid layer of tears : dependent on meibomian gland function ''. Experimental Eye Research. 78 ( 3 ) : 361 -- 5. doi : 10.1016 / s0014 - 4835 ( 03 ) 00203 - 3. PMID 15106913. Jump up ^ Dorland 's ( 2012 ). Dorland 's Illustrated Medical Dictionary ( 32nd ed. ). Elsevier Saunders. p. 781. ISBN 978 - 0 - 19 - 856878 - 0. Jump up ^ Dorland 's ( 2012 ). Dorland 's Illustrated Medical Dictionary ( 32nd ed. ). Elsevier Saunders. p. 802. ISBN 978 - 0 - 19 - 856878 - 0. Jump up ^ Roeser, RJ ; Ballachanda, BB ( December 1997 ). `` Physiology, pathophysiology, and anthropology / epidemiology of human earcanal secretions ''. Journal of the American Academy of Audiology. 8 ( 6 ) : 391 -- 400. PMID 9433685. ^ Jump up to : Britton, the editors Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston ; illustrated by Robert ( 2010 ). Davidson 's principles and practice of medicine ( 21st ed. ). Edinburgh : Churchill Livingstone / Elsevier. pp. 1267 -- 1268. ISBN 978 - 0 - 7020 - 3085 - 7. Jump up ^ Farrell LN, Strauss JS, Stranieri AM ; Strauss ; Stranieri ( December 1980 ). `` The treatment of severe cystic acne with 13 - cis - retinoic acid. Evaluation of sebum production and the clinical response in a multiple - dose trial ''. Journal of the American Academy of Dermatology. 3 ( 6 ) : 602 -- 11. doi : 10.1016 / S0190 - 9622 ( 80 ) 80074 - 0. PMID 6451637. CS1 maint : Multiple names : authors list ( link ) Jump up ^ Zhao YE, Peng Y, Wang XL, Wu LP, Wang M, Yan HL, Xiao SX ( 2011 ). `` Facial dermatosis associated with Demodex : a case - control study ''. J Zhejiang Univ Sci B. 12 ( 12 ) : 1008 -- 15. doi : 10.1631 / jzus. B1100179. PMC 3232434. PMID 22135150. Jump up ^ James, William D. ; Berger, Timothy G. ( 2006 ). Andrews ' Diseases of the Skin : clinical Dermatology. Saunders Elsevier. p. 662. ISBN 0 - 7216 - 2921 - 0. Jump up ^ Dessinioti, C. ; Katsambas, A. ( 2013 ). `` Seborrheic dermatitis : etiology, risk factors, and treatments : facts and controversies ''. Clin Dermatol. 31 ( 4 ) : 343 -- 51. doi : 10.1016 / j. clindermatol. 2013.01. 001. PMID 23806151. ^ Jump up to : Rapini, Ronald P. ; Bolognia, Jean L. ; Jorizzo, Joseph L. ( 2007 ). Dermatology : 2 - Volume Set. St. Louis : Mosby. ISBN 1 - 4160 - 2999 - 0. Jump up ^ Nelson BR, Hamlet KR, Gillard M, Railan D, Johnson TM ; Hamlet ; Gillard ; Railan ; Johnson ( July 1995 ). `` Sebaceous carcinoma ''. J. Am. Acad. Dermatol. 33 ( 1 ) : 1 -- 15, quiz 16 -- 8. doi : 10.1016 / 0190 - 9622 ( 95 ) 90001 - 2. PMID 7601925. CS1 maint : Multiple names : authors list ( link ) Jump up ^ Neville BW, Damm DD, Allen CA, Bouquot JE ( 2002 ). Oral & maxillofacial pathology ( 2nd ed. ). Philadelphia : W.B. Saunders. p. 31. ISBN 0 - 7216 - 9003 - 3. Jump up ^ Harper, Douglas. `` Sebaceous ''. Etymology Online. Retrieved 5 April 2014. ^ Jump up to : Astruc, Jean ( 1746 ). A General and Compleat Treatise on All the Diseases Incident to Children. J. Nourse. Jump up ^ Rosenthal, Stanley A ; Furnari, Domenica ( 1958 ). `` Slide Agglutination as a Presumptive Test in the Laboratory Diagnosis of Candida Albicans1 ''. The Journal of Investigative Dermatology. 31 ( 5 ) : 251 -- 253. doi : 10.1038 / jid. 1958.50. PMID 13598929. Jump up ^ Dobson, G.E. ( 1878 ). Catalogue of the Chiroptera in the collection of the British Museum. Order of the Trustees. Jump up ^ Gutierrez, M., & Aoki, A. ( 1973 ). Fine structure of the gular gland of the free ‐ tailed bat Tadarida brasiliensis. Journal of morphology, 141 ( 3 ), 293 - 305. Jump up ^ Heideman, P.D., Erickson, K.R., & Bowles, J.B. ( 1990 ). Notes on the breeding biology, gular gland and roost habits of Molossus sinaloae ( Chiroptera, Molossidae ). Zeitschrift für Säugetierkunde, 55 ( 5 ), 303 - 307. Jump up ^ Lars Mecklenburg ; Monika Linek ; Desmond J. Tobin ( 15 September 2009 ). Hair Loss Disorders in Domestic Animals. John Wiley & Sons. pp. 269 --. ISBN 978 - 0 - 8138 - 1934 - 1. External links Histology image : 08801loa -- Histology Learning System at Boston University - `` Integument : scalp '' Sebaceous + Glands at the US National Library of Medicine Medical Subject Headings ( MeSH ) Epithelial tissue Cells Squamous Cuboidal Columnar Types Simple squamous epithelium Endothelium Mesothelium Simple cuboidal epithelium Simple columnar epithelium Pseudostratified columnar epithelium Respiratory epithelium Stratified squamous epithelium Stratified cuboidal epithelium Stratified columnar epithelium Transitional epithelium Urothelium Glands Types Mechanism Merocrine Eccrine Apocrine Holocrine Sebaceous Meibomian Shape Tubular gland Alveolar gland Secretion Serous glands Mucous glands Components Myoepithelial cell Serous demilune Ducts : Interlobar Interlobular Intralobular Striated Intercalated Acinus / Lobe Skin and related structures Skin Epidermis Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum basale Basement membrane Basal keratinocyte Lamina lucida Lamina densa Dermis Papillary Dermal papillae Reticular Subcutaneous tissue Panniculus / Pannus ( Panniculus adiposus Panniculus carnosus ) Membranous layer Loose connective tissue Superficial fascia Adnexa Skin glands Sweat glands : Apocrine sweat gland Eccrine sweat gland Sebaceous Hair Root sheath Outer root sheath Inner root sheath Henle 's layer Huxley 's layer Hair shaft Cuticle Cortex Medulla Bulb with matrix cells Hair follicle Muscle Arrector pili muscle Pilosebaceous unit Hair sebaceous gland Nail Nail matrix Nail plate Lunula Eponychium Paronychium Hyponychium Retrieved from `` https://en.wikipedia.org/w/index.php?title=Sebaceous_gland&oldid=860298296 '' Categories : Skin anatomy Glands Secretion Hidden categories : CS1 maint : Multiple names : authors list Good articles Articles containing Latin - language text Use dmy dates from April 2017 Talk Contents About Wikipedia Беларуская Беларуская ( тарашкевіца ) ‎ Български Català Čeština Dansk Deutsch Ελληνικά Español Euskara فارسی Français Galego 한국어 Hrvatski Bahasa Indonesia Italiano עברית Қазақша Magyar മലയാളം Bahasa Melayu Nederlands 日本 語 Norsk Oʻzbekcha / ўзбекча Polski Português Русский Simple English Slovenščina Српски / srpski Srpskohrvatski / српскохрватски Suomi Svenska Tagalog Türkçe Українська 中文 31 more Edit links This page was last edited on 19 September 2018, at 18 : 16 ( UTC ). Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: the sebaceous glands are part of what system
Answer: integumentary system