Gastric chief cell - wikipedia Gastric chief cell Chief cell Human chief cells near tip of black pointer Details Part of Stomach System Digestive system Identifiers Latin exocrinocytus principalis TH H3. 04.02. 1.00031 Anatomical terminology ( edit on Wikidata ) A gastric chief cell ( or peptic cell, or gastric zymogenic cell ) is a type of cell in the stomach that releases pepsinogen and gastric lipase and is the cell responsible for secretion of chymosin in ruminants. The cell stains basophilic upon H&E staining due to the large proportion of rough endoplasmic reticulum in its cytoplasm. Gastric chief cells are generally located deep in the mucosal layer of the stomach lining. Chief cells release the zymogen ( enzyme precursor ) pepsinogen when stimulated by a variety of factors including cholinergic activity from the vagus nerve and acidic condition in the stomach. Gastrin and secretin may also act as secretagogues. It works in conjunction with the parietal cell, which releases gastric acid, converting the pepsinogen into pepsin. Contents 1 Nomenclature 2 See also 3 References 4 External links Nomenclature The terms chief cell and zymogenic cell are often used without the word `` gastric '' to name this type of cell. However those terms can also be used to describe other cell types ( for example, parathyroid chief cells ). Chief cells are also known as peptic cells. See also Gastric acid Fundic glands List of human cell types derived from the germ layers References Jump up ^ Kitamura N, Tanimoto A, Hondo E, Andrén A, Cottrell DF, Sasaki M, Yamada J ( 2001 ). `` Immunohistochemical study of the ontogeny of prochymosin -- and pepsinogen - producing cells in the abomasum of sheep ''. Anatomia, Histologia, Embryologia. 30 ( 4 ) : 231 -- 235. doi : 10.1046 / j. 1439 - 0264.2001. 00326. x. PMID 11534329. Jump up ^ Johnson. Gastrointestinal Physiology 6th Edition. Mosby. 2001 External links Anatomy Atlases - Microscopic Anatomy, plate 01.05 Histology image : 22201loa -- Histology Learning System at Boston University - `` Ultrastructure of the Cell : chief cells and enteroendocrine cell '' Histology image : 11304loa -- Histology Learning System at Boston University - `` Digestive System : Alimentary Canal : fundic stomach, gastric glands, base '' `` chief cell '' at Dorland 's Medical Dictionary Physiology : 6 / 6ch4 / s6ch4_8 - Essentials of Human Physiology Physiology of the gastrointestinal system GI tract Upper Exocrine Chief cells Pepsinogen Parietal cells Gastric acid Intrinsic factor Foveolar cells HCO Mucus Goblet cells Mucus Processes Swallowing Vomiting Fluids Saliva Gastric acid Lower Enteric nervous system Submucous plexus Myenteric plexus Endocrine / paracrine G cells gastrin D cells somatostatin ECL cells Histamine enterogastrone : I cells CCK K cells GIP S cells secretin Enteroendocrine cells Enterochromaffin cell APUD cell Fluids Intestinal juice Processes Segmentation contractions Migrating motor complex Borborygmus Defecation Either / both Processes Peristalsis ( Interstitial cell of Cajal Basal electrical rhythm ) Gastrocolic reflex Digestion Enterocyte Accessory Fluids Bile Pancreatic juice Processes Enterohepatic circulation Abdominopelvic Peritoneal fluid Retrieved from `` https://en.wikipedia.org/w/index.php?title=Gastric_chief_cell&oldid=830907665 '' Categories : Peptide hormone secreting cells Human cells Stomach Hidden categories : Pages with unresolved properties Talk Contents About Wikipedia Català Español Galego Bahasa Indonesia Қазақша 日本 語 Português Русский Suomi 中文 4 more Edit links This page was last edited on 17 March 2018, at 16 : 38. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: where are chief cells found in the stomach
Answer: deep in the mucosal layer of the stomach lining