Inositol - wikipedia Inositol myo - Inositol Names IUPAC name ( 1R, 2S, 3r, 4R, 5S, 6s ) - cyclohexane - 1, 2, 3, 4, 5, 6 - hexol Other names cis - 1, 2, 3, 5 - trans - 4, 6 - cyclohexanehexol, cyclohexanehexol, mouse antialopecia factor, nucite, phaseomannite, phaseomannitol, rat antispectacled eye factor, scyllite ( for the structural isomer scyllo - inositol ) Identifiers CAS Number 87 - 89 - 8 3D model ( JSmol ) Interactive image ChEBI CHEBI : 17268 ChEMBL ChEMBL1222251 ChemSpider 10239179 IUPHAR / BPS 4495 KEGG D08079 PubChem CID 892 UNII 4L6452S749 InChI InChI = 1S / C6H12O6 / c7 - 1 - 2 ( 8 ) 4 ( 10 ) 6 ( 12 ) 5 ( 11 ) 3 ( 1 ) 9 / h1 - 12H / t1 -, 2 -, 3 -, 4 +, 5 -, 6 - Key : CDAISMWEOUEBRE - GPIVLXJGSA - N InChI = 1 / C6H12O6 / c7 - 1 - 2 ( 8 ) 4 ( 10 ) 6 ( 12 ) 5 ( 11 ) 3 ( 1 ) 9 / h1 - 12H / t1 -, 2 -, 3 -, 4 +, 5 -, 6 - Key : CDAISMWEOUEBRE - GPIVLXJGBG SMILES ( C @ @ H ) 1 ( ( C @ @ H ) ( ( C @ @ H ) ( ( C @ @ H ) ( ( C@H ) ( ( C @ @ H ) 1O ) O ) O ) O ) O ) O Properties Chemical formula Molar mass 180.16 g / mol Density 1.752 g / cm Melting point 225 to 227 ° C ( 437 to 441 ° F ; 498 to 500 K ) Pharmacology ATC code A11HA07 ( WHO ) Hazards NFPA 704 0 0 Flash point 143 ° C ( 289 ° F ; 416 K ) Except where otherwise noted, data are given for materials in their standard state ( at 25 ° C ( 77 ° F ), 100 kPa ). Y verify ( what is ? ) Infobox references Inositol, or more precisely myo - inositol, is a carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation. It is a sugar alcohol with half the sweetness of sucrose ( table sugar ). It is made naturally in human beings from glucose. Each kidney makes 2g a day ; so 4g a day total is made. Other tissues synthesize it too, and the highest concentration is in the brain where it plays an important role making other neurotransmitters, and some steroid hormones bind to their receptors. Contents 1 Overview 2 Isomers and structure 3 Biosynthesis 4 Function 4.1 Phytic acid in plants 5 Use in explosives manufacture 6 Counter to road salt 7 Research and clinical applications 8 Use as a cutting agent 9 Nutritional sources 10 References 11 External links Overview myo - Inositol plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, the various inositol phosphates. In addition, inositol serves as an important component of the structural lipids phosphatidylinositol ( PI ) and its various phosphates, the phosphatidylinositol phosphate ( PIP ) lipids. Inositol or its phosphates and associated lipids are found in many foods, in particular fruit, especially cantaloupe and oranges. In plants, the hexaphosphate of inositol, phytic acid or its salts, the phytates, serve as phosphate stores in seed, for example in nuts and beans. Phytic acid also occurs in cereals with high bran content. Phytate is, however, not directly bioavailable to humans in the diet, since it is not digestible. Some food preparation techniques partly break down phytates to change this. However, inositol in the form of glycerophospholipids, as found in certain plant - derived substances such as lecithins is well - absorbed and relatively bioavailable. myo - Inositol ( free of phosphate ) was once considered a member of the vitamin B complex, called Vitamin B in this context. However, because it is produced by the human body from glucose, it is not an essential nutrient. Isomers and structure The isomer myo - inositol is a meso compound, and hence optically inactive, because it has a plane of symmetry. For this reason, meso - inositol is an obsolete name for this compound. Besides myo - inositol, the other naturally occurring stereoisomers are scyllo -, muco -, D - chiro -, and neo-inositol, although they occur in minimal quantities in nature. The other possible isomers are L - chiro -, allo -, epi -, and cis - inositol. As their names denote, L - and D - chiro inositol are the only pair of inositol enantiomers, but they are enantiomers of each other, not of myo - inositol. myo - scyllo - muco - chiro - neo - allo - epi - cis - In its most stable conformation, the myo - inositol isomer assumes the chair conformation, which moves the maximum number of hydroxyls to the equatorial position, where they are farthest apart from each other. In this conformation, the natural myo isomer has a structure in which five of the six hydroxyls ( the first, third, fourth, fifth, and sixth ) are equatorial, whereas the second hydroxyl group is axial. Biosynthesis myo - Inositol is synthesized from glucose - 6 - phosphate ( G - 6 - P ) in two steps. First, G - 6 - P is isomerised by an inositol - 3 - phosphate synthase enzyme ( for example, ISYNA1 ) to myo - inositol 1 - phosphate, which is then dephosphorylated by an inositol monophosphatase enzyme ( for example, IMPA1 ) to give free myo - inositol. In humans, most inositol is synthesized in the kidneys, typically in amounts of a few grams per day. Function Inositol, phosphatidylinositol and some of their mono - and polyphosphates function as secondary messengers in a number of intracellular signal transduction pathways. They are involved in a number of biological processes, including : Insulin signal transduction Cytoskeleton assembly Nerve guidance ( epsin ) Intracellular calcium ( Ca ) concentration control Cell membrane potential maintenance Breakdown of fats Gene expression In one important family of pathways, phosphatidylinositol 4, 5 - bisphosphate ( PIP ) is stored in cellular membranes until it is released by any of a number of signalling proteins and transformed into various secondary messengers, for example diacylglycerol and inositol triphosphate. Phytic acid in plants Inositolhexaphosphate, or phytic acid. Inositolhexaphosphate, also called phytic acid or IP6, is the principal storage form of phosphorus in many plant tissues, especially bran and seed. Phosphorus and inositol in phytate form are not generally bioavailable to non-ruminant animals because these animals lack the digestive enzyme phytase required to remove the phosphate groups. Ruminants are readily able to digest phytate because of the phytase produced by rumen microorganisms. Moreover, phytic acid also chelates important minerals such as calcium, magnesium, iron, and zinc, making them unabsorbable, and contributing to mineral deficiencies in people whose diets rely highly on bran and seeds for their mineral intake, such as occurs in developing countries. Inositol penta - ( IP5 ), tetra - ( IP4 ), and triphosphate ( IP3 ) are also called `` phytates ''. Use in explosives manufacture At the 1936 meeting of the American Chemical Society, professor Edward Bartow of the University of Iowa presented a commercially viable means of extracting large amounts of inositol from the phytic acid naturally present in waste corn. As a possible use for the chemical, he suggested ' inositol nitrate ' as a more stable alternative to nitroglycerin. Today, inositol nitrate is used to gelatinize nitrocellulose, thus can be found in many modern explosives and solid rocket propellants. Counter to road Salt When plants are exposed to increasing concentrations of road salt, the plant cells become dysfunctional and undergo apoptosis, leading to inhibited growth. Inositol pretreatment could reverse these effects. Research and clinical applications Large doses of inositol have been studied for treatment of depression, but insufficient evidence exists to determine whether this is an effective treatment. Inositol is effective in the management of preterm babies who have or are at a risk of infant respiratory distress syndrome ( RDS ). Inositol is considered a safe and effective treatment for polycystic ovary syndrome ( PCOS ). It works by increasing insulin sensitivity, which helps to improve ovarian function and reduce hyperandrogenism. It is also shown to reduce the risk of metabolic disease in people with PCOS. Use as a cutting agent Inositol has been used as an adulterant or cutting agent for many illegal drugs, such as cocaine, methamphetamine, and sometimes heroin, probably because of its solubility, powdery texture, or reduced sweetness ( 50 % ) compared to more common sugars. Inositol is also used as a stand - in film prop for cocaine in filmmaking. Nutritional sources myo - Inositol is naturally present in a variety of foods, although tables of food composition do not always distinguish between lecithin, the bioavailable form, and the unavailable phytate form in grains. Foods containing the highest concentrations of myo - inositol ( including its compounds ) include fruits, beans, grains, and nuts. Beans and grains, however, contain large amounts of phytate. References Jump up ^ Merck Index, 11th Edition, 4883. Jump up ^ Parthasarathy LK, Seelan RS, Tobias C, Casanova MF, Parthasarathy RN ( 2006 ). `` Mammalian inositol 3 - phosphate synthase : its role in the biosynthesis of brain inositol and its clinical use as a psychoactive agent ''. Sub-Cellular Biochemistry. 39 : 293 -- 314. PMID 17121280. Jump up ^ Croze ML, Soulage CO ( October 2013 ). `` Potential role and therapeutic interests of myo - inositol in metabolic diseases ''. Biochimie. 95 ( 10 ) : 1811 -- 27. doi : 10.1016 / j. biochi. 2013.05. 011. PMID 23764390. ^ Jump up to : Clements RS, Darnell B ( September 1980 ). `` Myo - inositol content of common foods : development of a high - myo - inositol diet ''. The American Journal of Clinical Nutrition. 33 ( 9 ) : 1954 -- 67. doi : 10.1093 / ajcn / 33.9. 1954. PMID 7416064. Jump up ^ `` Phytic acid ''. www.phytochemicals.info. Archived from the original on 2017 - 08 - 06. Retrieved 2017 - 10 - 02. Jump up ^ Reynolds, James E.F. ( January 1, 1993 ). Martindale : The Extra Pharmacopoeia. 30. Pennsylvania : Rittenhouse Book Distributors. p. 1379. ISBN 0 - 85369 - 300 - 5. An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man Jump up ^ Majumder AL, Biswas BB ( 2006 - 10 - 03 ). Biology of Inositols and Phosphoinositides. Springer Science & Business Media. ISBN 9780387276007. Jump up ^ Brady S, Siegel G, Albers RW, Price D ( 2005 - 11 - 11 ). Basic Neurochemistry : Molecular, Cellular and Medical Aspects. Academic Press. p. 348. ISBN 9780080472072. Jump up ^ Parthasarathy LK, Seelan RS, Tobias C, Casanova MF, Parthasarathy RN ( 2006 ). `` Mammalian inositol 3 - phosphate synthase : its role in the biosynthesis of brain inositol and its clinical use as a psychoactive agent ''. Sub-Cellular Biochemistry. 39 : 293 -- 314. PMID 17121280. Jump up ^ Larner J ( 2002 ). `` D - chiro - inositol -- its functional role in insulin action and its deficit in insulin resistance ''. International Journal of Experimental Diabetes Research. 3 ( 1 ) : 47 -- 60. doi : 10.1080 / 15604280212528. PMC 2478565. PMID 11900279. Jump up ^ Gerasimenko JV, Flowerdew SE, Voronina SG, Sukhomlin TK, Tepikin AV, Petersen OH, Gerasimenko OV ( December 2006 ). `` Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors ''. The Journal of Biological Chemistry. 281 ( 52 ) : 40154 -- 63. doi : 10.1074 / jbc. M606402200. PMID 17074764. Jump up ^ Kukuljan M, Vergara L, Stojilkovic SS ( February 1997 ). `` Modulation of the kinetics of inositol 1, 4, 5 - trisphosphate - induced ( Ca2+ ) i oscillations by calcium entry in pituitary gonadotrophs ''. Biophysical Journal. 72 ( 2 Pt 1 ) : 698 -- 707. Bibcode : 1997BpJ... 72... 698K. doi : 10.1016 / S0006 - 3495 ( 97 ) 78706 - X. PMC 1185595. PMID 9017197. Jump up ^ Rapiejko PJ, Northup JK, Evans T, Brown JE, Malbon CC ( November 1986 ). `` G - proteins of fat - cells. Role in hormonal regulation of intracellular inositol 1, 4, 5 - trisphosphate ''. The Biochemical Journal. 240 ( 1 ) : 35 -- 40. PMC 1147372. PMID 3103610. Jump up ^ Shen X, Xiao H, Ranallo R, Wu WH, Wu C ( January 2003 ). `` Modulation of ATP - dependent chromatin - remodeling complexes by inositol polyphosphates ''. Science. 299 ( 5603 ) : 112 -- 4. doi : 10.1126 / science. 1078068. PMID 12434013. Jump up ^ Steger DJ, Haswell ES, Miller AL, Wente SR, O'Shea EK ( January 2003 ). `` Regulation of chromatin remodeling by inositol polyphosphates ''. Science. 299 ( 5603 ) : 114 -- 6. doi : 10.1126 / science. 1078062. PMC 1458531. PMID 12434012. Jump up ^ 1937 --, Mathews, Christopher K., ( 2000 ). Biochemistry. Van Holde, K.E. ( Kensal Edward ), 1928 --, Ahern, Kevin G. ( 3rd ed. ). San Francisco, Calif. : Benjamin Cummings. p. 855. ISBN 0805330666. OCLC 42290721. Jump up ^ `` Phytic acid ''. www.phytochemicals.info. Archived from the original on 7 March 2018. Retrieved 2 May 2018. Jump up ^ Klopfenstein TJ, Angel R, Cromwell G, Erickson GE, Fox DG, Parsons C, Satter LD, Sutton AL, Baker DH ( July 2002 ). `` Animal Diet Modification to Decrease the Potential for Nitrogen and Phosphorus Pollution ''. Council for Agricultural Science and Technology. 21. Archived from the original on 2011 - 06 - 11. Jump up ^ Hurrell RF ( September 2003 ). `` Influence of vegetable protein sources on trace element and mineral bioavailability ''. The Journal of Nutrition. 133 ( 9 ) : 2973S -- 7S. doi : 10.1093 / jn / 133.9. 2973S. PMID 12949395. Jump up ^ Committee on Food Protection ; Food and Nutrition Board ; National Research Council ( 1973 ). `` Phytates ''. Toxicants Occurring Naturally in Foods. National Academy of Sciences. pp. 363 -- 371. ISBN 978 - 0 - 309 - 02117 - 3. Jump up ^ Laurence, William L. `` Corn by - product yields explosive '' Archived 2013 - 05 - 12 at the Wayback Machine., The New York Times. April 17, 1936. Page 7. Jump up ^ Ledgard, Jared. The Preparatory Manual of Explosives, 2007. p. 366. Jump up ^ Chatterjee J, Majumder AL ( September 2010 ). `` Salt - induced abnormalities on root tip mitotic cells of Allium cepa : prevention by inositol pretreatment ''. Protoplasma. 245 ( 1 -- 4 ) : 165 -- 72. doi : 10.1007 / s00709 - 010 - 0170 - 4. PMID 20559853. Jump up ^ Theerakulp P, Gunnula W ( 2012 ). `` Exogenous Sorbitol and Trehalose Mitigated Salt Stress Damage in Salt - sensitive but not Salt - tolerant Rice Seedlings ''. Asian Journal of Crop Science. 4 ( 4 ) : 165 -- 70. doi : 10.3923 / ajcs. 2012.165. 170. Jump up ^ Taylor MJ, Wilder H, Bhagwagar Z, Geddes J ( 2004 ). `` Inositol for depressive disorders ''. The Cochrane Database of Systematic Reviews ( 2 ) : CD004049. doi : 10.1002 / 14651858. CD004049. pub2. PMID 15106232. Jump up ^ Howlett A, Ohlsson A, Plakkal N ( February 2015 ). `` Inositol in preterm infants at risk for or having respiratory distress syndrome ''. The Cochrane Database of Systematic Reviews ( 2 ) : CD000366. doi : 10.1002 / 14651858. CD000366. pub3. PMID 25927089. Jump up ^ Monastra G, Unfer V, Harrath AH, Bizzarri M ( January 2017 ). `` Combining treatment with myo - inositol and D - chiro - inositol ( 40 : 1 ) is effective in restoring ovary function and metabolic balance in PCOS patients ''. Gynecological Endocrinology. 33 ( 1 ) : 1 -- 9. doi : 10.1080 / 09513590.2016. 1247797. PMID 27898267. Jump up ^ Nordio M, Proietti E ( May 2012 ). `` The combined therapy with myo - inositol and D - chiro - inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo - inositol supplementation alone ''. European Review for Medical and Pharmacological Sciences. 16 ( 5 ) : 575 -- 81. PMID 22774396. Jump up ^ `` Archived copy ''. Archived from the original on 2014 - 09 - 08. Retrieved 2013 - 07 - 21. CS1 maint : Archived copy as title ( link ) Jump up ^ Golianopoulos, Thomas. `` Drug Doubles : What Actors Actually Toke, Smoke and Snort on Camera ''. Wired Magazine. Archived from the original on 14 May 2012. Retrieved 14 May 2012. External links Wikimedia Commons has media related to Inositol. U.S. National Library of Medicine : Drug Information Portal -- Inositol Inositol MS Spectrum Inositol bound to proteins in the PDB Lipids : phospholipids Glycerol backbone ( Glycerophospholipids / Phosphoglycerides ) Phosphatidyl - : - ethanolamine / cephalin ( PE ) - choline / lecithin ( PC ) - serine ( PS ) - glycerol ( PG ) - inositol ( PI ) glyco - ( GPI ) Phosphoinositides : PIP PI ( 3 ) P PI ( 4 ) P PI ( 5 ) P PIP PI ( 3, 4 ) P PI ( 3, 5 ) P PI ( 4, 5 ) P PIP Ether lipids : Plasmalogen Platelet - activating factor Cardiolipin Sphingosine backbone Sphingomyelin Metabolites Inositol phosphate Inositol Lysophosphatidic acid Choline Phosphocholine Citicoline Sugar alcohols 2 - carbon Ethylene glycol 3 - carbon Glycerol 4 - carbon Erythritol Threitol 5 - carbon Arabitol Ribitol Xylitol 6 - carbon Mannitol Sorbitol Galactitol Iditol 7 - carbon Volemitol Deoxy sugar alcohols Fucitol Cyclic sugar alcohols Inositol Glycylglycitols Maltitol Lactitol Isomalt Maltotriitol Maltotetraitol Polyglycitol Purine receptor modulators Receptor ( ligands ) P0 ( adenine ) Agonists : 8 - Aminoadenine Adenine P1 ( adenosine ) Agonists : 2 - ( 1 - Hexynyl ) - N - methyladenosine 2 - Cl - IB - MECA 2 ' - MeCCPA 4 ' - O - β - D - Glucosyl - 9 - O - ( 6 ' ' - deoxysaccharosyl ) olivil 5 ' - N - ethylcarboxamidoadenosine Adenosine ADP AMP Apadenoson ATL - 146e ATP BAY 60 -- 6583 Binodenoson Capadenoson CCPA CGS - 21680 CP - 532,903 Evodenoson GR 79236 LUF - 5835 LUF - 5845 N - Cyclopentyladenosine Namodenoson Neladenoson dalanate Piclidenoson Regadenoson SDZ WAG 994 Selodenoson Sonedenoson Tecadenoson UK - 432,097 Antagonists : 8 - Chlorotheophylline 8 - Phenyl - 1, 3 - dipropylxanthine 8 - Phenyltheophylline Acefylline Aminophylline ATL - 444 Bamifylline Cafedrine Caffeine Caffeine citrate Cartazolate CGH - 2466 CGS - 15943 Choline theophyllinate Ciforadenant CPX CVT - 6883 Dimethazan DMPX DPCPX Dyphylline Enprofylline Etazolate Fenethylline IBMX Isovaleric acid Istradefylline KF - 26777 MRE3008F20 MRS - 1220 MRS - 1334 MRS - 1706 MRS - 1754 MRS - 3777 Paraxanthine Pentoxifylline Preladenant Propentofylline Proxyphylline PSB - 10 PSB - 11 PSB - 36 PSB - 603 PSB - 788 PSB - 1115 Reversine Rolofylline SCH - 442,416 SCH - 58261 Theacrine Theobromine Theodrenaline Theophylline Tozadenant Tracazolate VUF - 5574 ZM - 241,385 P2 ( nucleotide ) P2X ( ATP ) Agonists : 2 - Me - SATP α, β - Me - ATP Adenosine ADP AMP Ap4A Ap5A ATP ATPγS BzATP Cibacron blue CTP D - β, γ - Me - ATP GTP HT - AMP Ivermectin L - β, γ - Me - ATP MRS - 2219 PAPET - ATP UTP Zinc Antagonists : 5 - BDBD A-317491 A-438079 A-740003 A-804598 A-839977 AF - 353 AZ - 10606120 AZ - 11645373 BBG Calcium Calmidazolium Chelerythrine Copper Emodin ( Rheum officinale ) Evans Blue Gefapixant GW - 791343 HMA Ip5I isoPPADS JNJ - 47965567 KN - 04 KN - 62 Magnesium MRS - 2159 NF - 023 NF - 110 NF - 157 NF - 279 NF - 449 Opiranserin ( VVZ - 149 ) Oxidized - ATP Phenol Red Phenolphthalein PPADS PPNDS PSB - 12062 Puerarin ( Radix puerariae ) Purotoxin 1 RB - 2 Ro 0437626 Ro 51 RO - 3 Sodium ferulate ( Angelica sinensis, Ligusticum wallichii ) Suramin TC - P 262 Tetramethylpyrazine ( ligustrazine ) ( Ligusticum wallichii ) TNP - ATP Zinc P2Y Agonists : 2 - Me - SADP 2 - Me - SATP 2 - Thio - UTP 5 - Br - UDP 5 - OMe - UDP α, β - Me - ATP Adenosine ADP ADPβS Ap3A AR - C 67085MX ATP ATPγS CTP dATP Denufosol Diquafosol IDP ITP INS - 365 INS - 37217 MRS - 2365 MRS - 2690 MRS - 2693 MRS - 2768 MRS - 2957 MRS - 4062 NF - 546 PAPET - ATP PSB - 0474 PSB - 1114 UDP UDPβS UDP - galactose UDP - glucose UDP - N - acetylglucosamine Up3U UTP UTPγS Antagonists : 2 - Me - SAMP A3P5PS AMPαS Ap4A AR - C 66096 AR - C 67085MX AR - C 69931MX AR - C 118925XX ATP BzATP C1330 - 7 Cangrelor Clopidogrel Elinogrel Ip5I MRS - 2179 MRS - 2211 MRS - 2279 MRS - 2395 MRS - 2500 MRS - 2578 NF - 157 NF - 340 PIT PPADS Prasugrel PSB - 0739 RB - 2 Regrelor Suramin Ticagrelor Ticlopidine UDP Transporter ( blockers ) CNTs 6 - Hydroxy - 7 - methoxyflavone Adenosine dMeThPmR Estradiol KGO - 2142 KGO - 2173 MeThPmR Phloridzin Progesterone ENTs Barbiturates Benzodiazepines Cilostazol Dilazep Dipyridamole Estradiol Ethanol Hexobendine NBMPR Pentoxifylline Progesterone Propentofylline PMAT Decynium - 22 Enzyme ( inhibitors ) XO Allopurinol Amflutizole Benzbromarone Caffeic acid Cinnamaldehyde Cinnamomum osmophloeum Febuxostat Myo - inositol Kaempferol Myricetin Niraxostat Oxipurinol Phytic acid Pistacia integerrima Propolis Quercetin Tisopurine Topiroxostat Others Aminopterin Azathioprine Methotrexate Mycophenolic acid Pemetrexed Pralatrexate Many others Others Precursors : Adenine Adenosine AMP ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others : Chrysophanol ( rhubarb ) See also : Receptor / signaling modulators Obsessive -- compulsive disorder ( F42, 300.3 ) History Yale -- Brown Obsessive Compulsive Scale Biology Neuroanatomy Basal ganglia ( striatum ) Orbitofrontal cortex Cingulate cortex Brain - derived neurotrophic factor Receptors 5 - HT β 5 - HT 5 - HT μ Opioid NK NMDA Symptoms Obsessions ( associative diagnostic injurious scrupulous pathogenic sexual ) Compulsions ( impulses, rituals tics ) Thought suppression ( avoidance ) Hoarding ( animals, books possessions ) Treatment Serotonergics Selective serotonin reuptake inhibitors Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline Citalopram Nefazodone Serotonin -- norepinephrine reuptake inhibitors Venlafaxine Desvenlafaxine Duloxetine Serotonin -- norepinephrine -- dopamine reuptake inhibitors Nefazodone Monoamine oxidase inhibitors Phenelzine Tranylcypromine Tricyclic antidepressants Clomipramine Serotonergic psychedelics Lysergic acid diethylamide Psilocin Atypical antipsychotics Aripiprazole Quetiapine Mu opioidergics Hydrocodone Morphine Tramadol Anticholinergics Diphenhydramine NMDA glutamatergics Riluzole NK - 1 tachykininergics Aprepitant Other Nicotine Memantine Tautomycin Behavioral Cognitive behavioral therapy ( Exposure and response prevention ) Inference - based therapy Organizations International OCD Foundation OCD Action Notable people Edna B. Foa Stanley Rachman Adam S. Radomsky Jeffrey M. Schwartz Susan Swedo Emily Colas Popular culture Literature / Comics Fictional Matchstick Men Plyushkin Xenocide Nonfiction Everything in Its Place Just Checking Media As Good as It Gets The Aviator Matchstick Men Adrian Monk `` $ pringfield '' Related Obsessive -- compulsive personality disorder Obsessional jealousy Primarily Obsessional OCD Relationship obsessive -- compulsive disorder Social anxiety disorder Tourette syndrome Retrieved from `` https://en.wikipedia.org/w/index.php?title=Inositol&oldid=865168544 '' Categories : Obsessive -- compulsive disorder Inositol Xanthine oxidase inhibitors Chemopreventive agents Biology of bipolar disorder Treatment of obsessive -- compulsive disorder Biology of obsessive -- compulsive disorder Hidden categories : Webarchive template wayback links CS1 maint : Archived copy as title Articles with incomplete citations from March 2017 All articles with incomplete citations Articles containing unverified chemical infoboxes Chembox image size set All articles with unsourced statements Articles with unsourced statements from January 2015 Talk Contents About Wikipedia Afrikaans تۆرکجه Català Čeština Deutsch Eesti Español فارسی Français Gaeilge Galego 한국어 Հայերեն हिन्दी Bahasa Indonesia Italiano ಕನ್ನಡ Қазақша Magyar Nederlands 日本 語 Norsk nynorsk Polski Português Română Русский Српски / srpski Srpskohrvatski / српскохрватски Suomi Svenska Українська 中文 24 more Edit links This page was last edited on 22 October 2018, at 06 : 09 ( UTC ). 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Question: what is the physiological role of inositol in the human body
Answer: mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors