Perspiration - wikipedia Perspiration `` Sweat '' redirects here. For other uses, see Sweat ( disambiguation ). `` Perspire '' redirects here. For the song by Gigolo Aunts, see Tales from the Vinegar Side. Perspiration Synonyms Sweating, hidrosis, diaphoresis Droplets of perspiration on the skin Classification and external resources Specialty Dermatology MedlinePlus 003218 MeSH D013546 ( edit on Wikidata ) Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals. Two types of sweat glands can be found in humans : eccrine glands and apocrine glands. The eccrine sweat glands are distributed over much of the body. In humans, sweating is primarily a means of thermoregulation, which is achieved by the water - rich secretion of the eccrine glands. Maximum sweat rates of an adult can be up to 2 -- 4 liters per hour or 10 -- 14 liters per day ( 10 -- 15 g / min m2 ), but is less in children prior to puberty. Evaporation of sweat from the skin surface has a cooling effect due to evaporative cooling. Hence, in hot weather, or when the individual 's muscles heat up due to exertion, more sweat is produced. Animals with few sweat glands, such as dogs, accomplish similar temperature regulation results by panting, which evaporates water from the moist lining of the oral cavity and pharynx. Horses have armpits that sweat like those of primates such as humans. Although sweating is found in a wide variety of mammals, relatively few ( exceptions include humans and horses ) produce large amounts of sweat in order to cool down. Contents 1 Definitions 2 Signs and symptoms 3 Causes 3.1 Pathological sweating 3.2 Hyperhidrosis 3.3 Night sweats 4 Mechanism 5 Composition 6 Society and culture 6.1 Artificial perspiration 6.2 Diagnostics 7 See also 8 References 9 Further reading Definitions The words diaphoresis and hidrosis both can mean either perspiration ( in which sense they are synonymous with sweating ) or excessive perspiration ( in which sense they can be either synonymous with hyperhidrosis or differentiable from it only by clinical criteria involved in narrow specialist senses of the words ). Hypohidrosis is decreased sweating from whatever cause. Focal hyperhidrosis is increased or excessive sweating in certain regions such as the underarm, palms, soles, face, or groin. Hyperhidrosis is excessive sweating, usually secondary to an underlying condition ( in which case it is called secondary hyperhidrosis ) and usually involving the body as a whole ( in which case it is called generalized hyperhidrosis ). Hidromeiosis is a reduction in sweating that is due to blockages of sweat glands in humid conditions. Signs and symptoms Sweat contributes to body odor when it is metabolized by beneficial bacteria on the skin. Medications that are used for other treatments and diet also affect odor. Some medical conditions, such as kidney failure and diabetic ketoacidosis, can also affect sweat odor. Areas that produce excessive sweat usually appear pink or white, but, in severe cases, may appear cracked, scaly, and soft. Causes This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. ( March 2016 ) A man in a collared shirt sweats after exertion. Diaphoresis is a non-specific symptom or sign, which means that it has many possible causes. Some causes of diaphoresis include physical exertion, menopause, fever, ingestion of toxins or irritants, and high environmental temperature. Strong emotions ( anger, fear, anxiety ) and recall of past trauma can also trigger sweating. The vast majority of sweat glands in the body are innervated by sympathetic cholinergic neurons. Sympathetic postganglionic neurons typically secrete norepinephrine and are named sympathetic adrenergic neurons ; however, the sympathetic postganglionic neurons that innervate sweat glands secrete acetylcholine and hence are termed sympathetic cholinergic neurons. Sweat glands, piloerector muscles, and some blood vessels are innervated by sympathetic cholinergic neurons. Pathological sweating This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. ( March 2016 ) Diaphoresis may be associated with some abnormal conditions, such as hyperthyroidism and shock. If it is accompanied by unexplained weight loss or fever or by palpitations, shortness of breath, or chest discomfort, it suggests serious illness. Diaphoresis is also seen in an acute myocardial infarction ( heart attack ), from the increased firing of the sympathetic nervous system, and is frequent in serotonin syndrome. Diaphoresis can also be caused by many types of infections, often accompanied by fever and / or chills. Most infections can cause some degree of diaphoresis and it is a very common symptom in some serious infections such as malaria and tuberculosis. In addition, pneumothorax can cause diaphoresis with splinting of the chest wall. Neuroleptic malignant syndrome and other malignant diseases ( e.g. leukemias ) can also cause diaphoresis. Diabetics relying on insulin shots or oral medications may have low blood sugar ( hypoglycemia ), which can also cause diaphoresis. Drugs ( including caffeine, morphine, alcohol, antidepressants and certain antipsychotics ) may be causes, as well as withdrawal from alcohol, benzodiazepines, nonbenzodiazepines or narcotic painkiller dependencies. Sympathetic nervous system stimulants such as cocaine and amphetamines have also been associated with diaphoresis. Diaphoresis due to ectopic catecholamine is a classic symptom of a pheochromocytoma, a rare tumor of the adrenal gland. Acetylcholinesterase inhibitors ( e.g. some insecticides ) also cause contraction of sweat gland smooth muscle leading to diaphoresis. Mercury is well known for its use as a diaphoretic, and was widely used in the 19th and early 20th century by physicians to `` purge '' the body of an illness. However, due to the high toxicity of mercury, secondary symptoms would manifest, which were erroneously attributed to the former disease that was being treated with mercurials. Infantile acrodynia ( childhood mercury poisoning ) is characterized by excessive perspiration. A clinician should immediately consider acrodynia in an afebrile child who is sweating profusely. Some people can develop a sweat allergy. The allergy is not due to the sweat itself but instead to an allergy - producing protein secreted by bacteria found on the skin. Tannic - acid has been found to suppress the allergic response along with showering. Hyperhidrosis Further information : Hyperhidrosis In some people, the body 's mechanism for cooling itself is overactive -- so overactive that they may sweat four or five times more than is typical. Millions of people are affected by this condition, but more than half never receive treatment due to embarrassment or lack of awareness. While it most commonly affects the armpits, feet, and hands, it is possible for someone to experience this condition over their whole body. The face is another common area for hyperhidrosis to be an issue. Sweating uncontrollably is not always expected and may be embarrassing to sufferers of the condition. It can cause both physiological and emotional problems in patients. It is generally an inherited problem that is found in each ethnic group. It is not life - threatening, but it is threatening to a person 's quality of life. A treatment modality is clipping of the sympathetic nerve at the level of T4 by thoracoscopic means. Night sweats Main article : Night sweats Mechanism The evaporation of sweat on the skin cools the body. Sweating allows the body to regulate its temperature. Sweating is controlled from a center in the preoptic and anterior regions of the brain 's hypothalamus, where thermosensitive neurons are located. The heat - regulatory function of the hypothalamus is also affected by inputs from temperature receptors in the skin. High skin temperature reduces the hypothalamic set point for sweating and increases the gain of the hypothalamic feedback system in response to variations in core temperature. Overall, however, the sweating response to a rise in hypothalamic ( ' core ' ) temperature is much larger than the response to the same increase in average skin temperature. Sweating causes a decrease in core temperature through evaporative cooling at the skin surface. As high energy molecules evaporate from the skin, releasing energy absorbed from the body, the skin and superficial vessels decrease in temperature. Cooled venous blood then returns to the body 's core and counteracts rising core temperatures. There are two situations in which the nerves will stimulate the sweat glands, causing perspiration : during physical heat and during emotional stress. In general, emotionally induced sweating is restricted to palms, soles, armpits, and sometimes the forehead, while physical heat - induced sweating occurs throughout the body. People have an average of two to four million sweat glands. But how much sweat is released by each gland is determined by many factors, including gender, genetics, environmental conditions, age or fitness level. Two of the major contributors to sweat rate are an individual 's fitness level and weight. If an individual weighs more, sweat rate is likely to increase because the body must exert more energy to function and there is more body mass to cool down. On the other hand, a fit person will start sweating earlier and more readily. As someone becomes fit, the body becomes more efficient at regulating the body 's temperature and sweat glands adapt along with the body 's other systems. Sweat is not pure water ; it always contains a small amount ( 0.2 -- 1 % ) of solute. When a person moves from a cold climate to a hot climate, adaptive changes occur in the sweating mechanisms of the person. This process is referred to as acclimatisation : the maximum rate of sweating increases and its solute composition decreases. The volume of water lost in sweat daily is highly variable, ranging from 100 to 8,000 mL / day. The solute loss can be as much as 350 mmol / day ( or 90 mmol / day acclimatised ) of sodium under the most extreme conditions. During average intensity exercise, sweat losses can average up to 2 litres of water / hour. In a cool climate and in the absence of exercise, sodium loss can be very low ( less than 5 mmols / day ). Sodium concentration in sweat is 30 - 65 mmol / l, depending on the degree of acclimatisation. Composition Beads of sweat emerging from eccrine glands Sweat is mostly water. A microfluidic model of the eccrine sweat gland provides details on what solutes partition into sweat, their mechanisms of partitioning, and their fluidic transport to the skin surface. Dissolved in the water are trace amounts of minerals, lactic acid, and urea. Although the mineral content varies, some measured concentrations are : sodium ( 0.9 gram / liter ), potassium ( 0.2 g / l ), calcium ( 0.015 g / l ), and magnesium ( 0.0013 g / l ). Relative to the plasma and extracellular fluid, the concentration of Na ions is much lower in sweat ( ~ 40 mM in sweat versus ~ 150 mM in plasma and extracellular fluid ). Initially, within eccrine glands sweat has a high concentration of Na ions. In the sweat ducts, the Na ions are re-absorbed into tissue by epithelial sodium channels ( ENaC ) that are located on the apical membrane of epithelial cells that form the duct ( see Fig. 9 of the reference ). Many other trace elements are also excreted in sweat, again an indication of their concentration is ( although measurements can vary fifteenfold ) zinc ( 0.4 milligrams / liter ), copper ( 0.3 -- 0.8 mg / l ), iron ( 1 mg / l ), chromium ( 0.1 mg / l ), nickel ( 0.05 mg / l ), and lead ( 0.05 mg / l ). Probably many other less - abundant trace minerals leave the body through sweating with correspondingly lower concentrations. Some exogenous organic compounds make their way into sweat as exemplified by an unidentified odiferous `` maple syrup '' scented compound in several of the species in the mushroom genus Lactarius. In humans, sweat is hypoosmotic relative to plasma ( i.e. less concentrated ). Sweat is found at moderately acidic to neutral pH levels, typically between 4.5 and 7.0. Society and culture Artificial perspiration Artificial skin capable of sweating similar to natural sweat rates and with the surface texture and wetting properties of regular skin has been developed for research purposes. Artificial perspiration is also available for in - vitro testing, and contains 19 amino acids and the most abundant minerals and metabolites in sweat. Diagnostics There is interest in its use in wearable technology. Sweat can be sampled and sensed non-invasively and continuously using electronic tattoos, bands, or patches. However, sweat as a diagnostic fluid presents numerous challenges as well, such as very small sample volumes and filtration ( dilution ) of larger - sized hydrophilic analytes. Currently the only major commercial application for sweat diagnostics is for infant cystic fibrosis testing based on sweat chloride concentrations. See also Apocrine Body odor Deodorant Hidradenitis suppurativa Hyperhydrosis Hyperthermia Hyponatremia Pheromones Sweat Diagnostics Sauna suit Sweat therapy Transpiration References Jump up ^ Mosher HH ( 1933 ). `` Simultaneous Study of Constituents of Urine and Perspiration '' ( PDF ). The Journal of Biological Chemistry. 99 ( 3 ) : 781 -- 790. ^ Jump up to : Hanukoglu I, Boggula VR, Vaknine H, Sharma S, Kleyman T, Hanukoglu A ( January 2017 ). `` Expression of epithelial sodium channel ( ENaC ) and CFTR in the human epidermis and epidermal appendages ''. Histochemistry and Cell Biology. 147 ( 6 ) : 733 -- 748. doi : 10.1007 / s00418 - 016 - 1535 - 3. PMID 28130590. Jump up ^ Jessen, C. ( 2000 ). Temperature Regulation in Humans and Other Mammals. Berlin : Springer. ISBN 3 - 540 - 41234 - 4. Jump up ^ Mack, G.W. ; Nadel, E.R. ( 1996 ). `` Body fluid balance during heat stress in humans ''. In Fregly, M.J. ; Blatteis, C.M. Handbook of Physiology. Section 4 : Environmental Physiology. New York : Oxford University Press. pp. 187 -- 214. ISBN 0 - 19 - 507492 - 0. Jump up ^ Sawka, M.L. ; Wenger, C.B. ; Pandolf, K.B. ( 1996 ). `` Thermoregulatory responses to acute exercise - heat stress and heat acclimation ''. In Fregly, M.J. ; Blatteis, C.M. Handbook of Physiology. Section 4 : Environmental Physiology. New York : Oxford University Press. ISBN 0 - 19 - 507492 - 0. Jump up ^ Epps, Henry. Survival. Lulu.com. ISBN 9781300158509. Jump up ^ Goglia G ( January 1953 ). `` ( Further research on the branched sweat glands in some mammals ( Cavia cobaya, Sus scrofa, Equus caballus ). ) ''. Bollettino Della Società Italiana Di Biologia Sperimentale. 29 ( 1 ) : 58 -- 60. PMID 13066656. Jump up ^ Robertshaw D, Taylor CR ( November 1969 ). `` Sweat gland function of the donkey ( Equus asinus ) ''. The Journal of Physiology. 205 ( 1 ) : 79 -- 89. doi : 10.1113 / jphysiol. 1969. sp008952. PMC 1348626. PMID 5347721. Jump up ^ McDonald RE, Fleming RI, Beeley JG, et al. ( 2009 ). Koutsopoulos S, ed. `` Latherin : A Surfactant Protein of Horse Sweat and Saliva ''. PLoS ONE. 4 ( 5 ) : e5726. doi : 10.1371 / journal. pone. 0005726. PMC 2684629. PMID 19478940. Jump up ^ Elsevier, Dorland 's Illustrated Medical Dictionary, Elsevier. Jump up ^ Wolters Kluwer, Stedman 's Medical Dictionary, Wolters Kluwer. ^ Jump up to : `` Academy of Hyperhidrosis ''. Allaboutsweat.com. Retrieved 2014 - 04 - 05. Jump up ^ Parsons K ( 2009 ). `` Maintaining health, comfort and productivity in heat waves ''. Glob Health Action. 2. doi : 10.3402 / gha. v2i0. 2057. PMC 2799322. PMID 20052377. Jump up ^ Excessive Sweating Information on Healthline.com, Retrieved on 2010 - 01 - 25. Jump up ^ Boron, Walter F., and Emile L. Boulpaep. `` Sweating. '' Medical Physiology. Updated 2nd ed. Philadelphia : Elsevier, 2012. 1260 - 264. Print. Jump up ^ Neuroleptic Malignant Syndrome ~ clinical at eMedicine ^ Jump up to : Hiragun, Takaaki ; Hiragun, Makiko ; Ishii, Kaori ; Kan, Takanobu ; Hide, Michihiro. `` Sweat allergy : Extrinsic or intrinsic ? ''. Journal of Dermatological Science. 87 ( 1 ) : 3 -- 9. doi : 10.1016 / j. jdermsci. 2017.03. 002. Jump up ^ Hiragun, Takaaki ; Hide, Michihiro ( 2016 ). Sweat Allergy. 51. Karger Publishers. pp. 101 -- 108. doi : 10.1159 / 000446788. Jump up ^ Yokozeki, Hiroo ( 2016 ). Perspiration research. Basel New York : Karger. p. 52. ISBN 9783318059052. Jump up ^ International Hyperhidrosis Society : About Hyperhidrosis, Retrieved on 2010 - 01 - 25. Jump up ^ Kameia, Tomoya ; Tsudab, Takao ; Kitagawab, Shinya ; Naitoha, Ken ; Nakashimaa, Koji ; Ohhashi, Toshio ( June 1998 ). `` Physical stimuli and emotional stress - induced sweat secretions in the human palm and forehead ''. Analytica Chimica Acta. 365 ( 1 -- 3 ) : 319 -- 326. doi : 10.1016 / S0003 - 2670 ( 97 ) 00642 - 9. Jump up ^ Hansen, Julieann. `` The Science of Sweat ''. American College of Sports Medicine. Retrieved 19 September 2013. Jump up ^ Sonner, Z. ; Wilder, E. ; Heikenfeld, J. ; Kasting, G. ; Beyette, F. ; Swaile, D. ; Sherman, F. ; Joyce, J. ; Hagen, J. ( 2015 - 05 - 01 ). `` The microfluidics of the eccrine sweat gland, including biomarker partitioning, transport, and biosensing implications ''. Biomicrofluidics. 9 ( 3 ) : 031301. doi : 10.1063 / 1.4921039. ISSN 1932 - 1058. PMC 4433483. PMID 26045728. Jump up ^ Montain, S.J. ; Cheuvront, S.N. ; Lukaski, H.C. ( 2007 ). `` Sweat mineral - element responses during 7 h of exercise - heat stress ''. International journal of sport nutrition and exercise metabolism. 17 ( 6 ) : 574 -- 582. PMID 18156662. Jump up ^ Cohn JR, Emmett EA ( 1978 ). `` The excretion of traces of metals in human sweat ''. Annals of Clinical and Laboratory Science. 8 ( 4 ) : 270 -- 5. PMID 686643. Jump up ^ Saraymen, Recep ; Kılıç, Eser ; Yazar, Süleyman ( 2004 ). `` Sweat Copper, Zinc, Iron, Magnesium and Chromium Levels in National Wrestler ''. İnönü Üniversitesi Tıp Fakültesi Dergisi. 11 ( 1 ) : 7 -- 10. Jump up ^ Aurora, David `` Lactarius fragilis '' Mushrooms Demystified 1986 Ten Speed Press, Berkeley California Jump up ^ Constanzo, Linda S. BRS Physiology ( 6th ed. ). p. 151. Jump up ^ Bandodkar AJ, Hung VW, Jia W, Ramirez GV, Windmiller JR, Martinez AG, Ramirez J, Chan G, Kagan K, Wang J ( 2013 ). `` Tattoo - based potentiometric ion - selective sensors for epidermal pH monitoring ''. Analyst. 138 ( 1 ) : 123 -- 8. doi : 10.1039 / c2an36422k. Jump up ^ Hou, Linlin ; Hagen, Joshua ; Wang, Xiao ; Papautsky, Ian ; Naik, Rajesh ; Kelley - Loughnane, Nancy ; Heikenfeld, Jason. `` Artificial microfluidic skin for in vitro perspiration simulation and testing ''. pubs.rsc.org. doi : 10.1039 / C3LC41231H. Retrieved 2015 - 11 - 13. Jump up ^ Heikenfeld, Jason ( 2016 ). `` Non-invasive Analyte Access and Sensing through Eccrine Sweat : Challenges and Outlook circa 2016 ''. Electroanalysis. 28 ( 6 ). doi : 10.1002 / elan. 201600018. Further reading Wikimedia Commons has media related to Perspiration. Ferner S, Koszmagk R, Lehmann A, Heilmann W ( 1990 ). `` ( Reference values of Na ( + ) and Cl ( - ) concentrations in adult sweat ) ''. Zeitschrift für Erkrankungen der Atmungsorgane ( in German ). 175 ( 2 ) : 70 -- 5. PMID 2264363. Nadel ER, Bullard RW, Stolwijk JA ( July 1971 ). `` Importance of skin temperature in the regulation of sweating ''. Journal of Applied Physiology. 31 ( 1 ) : 80 -- 7. PMID 5556967. Sato K, Kang WH, Saga K, Sato KT ( April 1989 ). `` Biology of sweat glands and their disorders. I. Normal sweat gland function ''. Journal of the American Academy of Dermatology. 20 ( 4 ) : 537 -- 63. doi : 10.1016 / S0190 - 9622 ( 89 ) 70063 - 3. PMID 2654204. NDL : 00560379 Skin and related structures Skin Epidermis Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum basale Basement membrane Basal keratinocyte Lamina lucida Lamina densa Dermis Papillary Dermal papillae Reticular Subcutaneous tissue Panniculus / Pannus ( Panniculus adiposus Panniculus carnosus ) Membranous layer Loose connective tissue Superficial fascia Adnexa Skin glands Sweat glands : Apocrine sweat gland Eccrine sweat gland Sebaceous Hair Root sheath Outer root sheath Inner root sheath Henle 's layer Huxley 's layer Hair shaft Cuticle Cortex Medulla Bulb with matrix cells Hair follicle Muscle Arrector pili muscle Pilosebaceous unit Hair sebaceous gland Nail Nail matrix Nail plate Lunula Eponychium Paronychium Hyponychium Retrieved from `` https://en.wikipedia.org/w/index.php?title=Perspiration&oldid=811695225 '' Categories : Animal physiology Body fluids Excretion Reflexes Hidden categories : Infobox medical condition Articles needing additional references from March 2016 All articles needing additional references All articles with unsourced statements Articles with unsourced statements from November 2017 Articles with unsourced statements from July 2015 Articles with unsourced statements from October 2016 CS1 German - language sources ( de ) Talk Contents About Wikipedia Asturianu Авар Aymar aru Azərbaycanca Беларуская Беларуская ( тарашкевіца ) ‎ भोजपुरी Български Bosanski Brezhoneg Català Čeština Cymraeg Dansk Deutsch ދިވެހިބަސް Eesti Ελληνικά Español Esperanto Euskara فارسی Français Gaeilge Galego 贛 語 한국어 Հայերեն हिन्दी Hrvatski Ido Bahasa Indonesia Ирон Íslenska Italiano עברית ಕನ್ನಡ ქართული Kiswahili Кыргызча Лакку Latina Latviešu Lietuvių मराठी Bahasa Melayu Mìng - dĕ̤ng - ngṳ̄ Nederlands नेपाली 日本 語 Norsk ਪੰਜਾਬੀ Polski Português Română Runa Simi Русский Simple English Slovenčina Slovenščina Српски / srpski Srpskohrvatski / српскохрватски Basa Sunda Suomi Svenska Tagalog தமிழ் తెలుగు ไทย Тоҷикӣ Türkçe Українська اردو Tiếng Việt ייִדיש 粵語 中文 Edit links This page was last edited on 23 November 2017, at 09 : 00. 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Question: sweating can have a cooling effect due to
Answer: evaporative cooling