Genetic variation - wikipedia Genetic variation This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. ( November 2016 ) Part of a series on Evolutionary biology Diagrammatic representation of the divergence of modern taxonomic groups from their common ancestor Key topics Introduction to evolution Common descent Evidence of common descent Processes and outcomes Population genetics Variation Diversity Mutation Natural selection Adaptation Polymorphism Genetic drift Gene flow Speciation Adaptive radiation Co-operation Coevolution Divergence Convergence Parallel evolution Extinction Natural history Origin of life History of life Timeline of evolution Human evolution Phylogeny Biodiversity Biogeography Classification Evolutionary taxonomy Cladistics Transitional fossil Extinction event History of evolutionary theory Overview Renaissance Before Darwin Darwin Origin of Species Before synthesis Modern synthesis Molecular evolution Evo - devo Current research History of paleontology ( timeline ) Fields and applications Applications of evolution Biosocial criminology Ecological genetics Evolutionary aesthetics Evolutionary anthropology Evolutionary computation Evolutionary ecology Evolutionary economics Evolutionary epistemology Evolutionary ethics Evolutionary game theory Evolutionary linguistics Evolutionary medicine Evolutionary neuroscience Evolutionary physiology Evolutionary psychology Experimental evolution Phylogenetics Paleontology Selective breeding Sociobiology Systematics Universal Darwinism Social implications Evolution as fact and theory Social effects Creation -- evolution controversy Objections to evolution Level of support Evolutionary biology portal Book Related topics Darwin 's finches or Galapagos finches. Genetic variation means that biological systems -- individuals and populations -- are different over space. Each gene pool includes various alleles of genes. The variation occurs both within and among populations, supported by individual carriers of the variant genes. Genetic variation is brought about, fundamentally, by mutation, which is a permanent change in the chemical structure of chromosomes. Genetic recombination also produces changes within alleles. Contents 1 Among individuals within a population 2 Between populations 3 Measurement 4 Sources 5 Forms 6 Maintenance in populations 7 See also 8 References 9 Further reading 10 External links Among individuals within a population Genetic variation among individuals within a population can be identified at a variety of levels. It is possible to identify genetic variation from observations of phenotypic variation in either quantitative traits ( traits that vary continuously and are coded for by many genes ( e.g., leg length in dogs ) ) or discrete traits ( traits that fall into discrete categories and are coded for by one or a few genes ( e.g., white, pink, red petal color in certain flowers ) ). Genetic variation can also be identified by examining variation at the level of enzymes using the process of protein electrophoresis. Polymorphic genes have more than one allele at each locus. Half of the genes that code for enzymes in insects and plants may be polymorphic, whereas polymorphisms are less common in vertebrates. Ultimately, genetic variation is caused by variation in the order of bases in the nucleotides in genes. New technology now allows scientists to directly sequence DNA which has identified even more genetic variation than was previously detected by protein electrophoresis. Examination of DNA has shown genetic variation in both coding regions and in the non-coding intron region of genes. Genetic variation will result in phenotypic variation if variation in the order of nucleotides in the DNA sequence results in a difference in the order of amino acids in proteins coded by that DNA sequence, and if the resultant differences in amino acid sequence influence the shape, and thus the function of the enzyme. Between populations Geographic variation means genetic differences in populations from different locations. This is caused by natural selection or genetic drift. Measurement Genetic variation within a population is commonly measured as the percentage of gene loci that are polymorphic or the percentage of gene loci in individuals that are heterozygous. Sources A range of variability in the mussel Donax variabilis Random mutations are the ultimate source of genetic variation. Mutations are likely to be rare and most mutations are neutral or deleterious, but in some instances the new alleles can be favored by natural selection. Polyploidy is an example of chromosomal mutation. Polyploidy is a condition wherein organisms have three or more sets of genetic variation ( 3n or more ). Crossing over and random segregation during meiosis can result in the production of new alleles or new combinations of alleles. Furthermore, random fertilization also contributes to variation. Variation and recombination can be facilitated by transposable genetic elements, endogenous retroviruses, LINEs, SINEs, etc. For a given genome of a multicellular organism, genetic variation may be acquired in somatic cells or inherited through the germline. Forms Genetic variation can be divided into different forms according to the size and type of genomic variation underpinning genetic change. Small - scale sequence variation ( < 1Kbp ) includes base - pair substitution and indels. Large - scale Structural variation ( > 1Kbp ) can be either copy number variation ( loss or gain ), or chromosomal rearrangement ( translocation, inversion, or Segmental acquired uniparental disomy ). Genetic variation and recombination by transposable elements and endogenous retroviruses sometimes is supplemented by a variety of persistent viruses and their defectives which generate genetic novelty in host genomes. Numerical variation in whole chromosomes or genomes can be either polyploidy or aneuploidy. Maintenance in populations A variety of factors maintain genetic variation in populations. Potentially harmful recessive alleles can be hidden from selection in the heterozygous individuals in populations of diploid organisms ( recessive alleles are only expressed in the less common homozygous individuals ). Natural selection can also maintain genetic variation in balanced polymorphisms. Balanced polymorphisms may occur when heterozygotes are favored or when selection is frequency dependent. See also Genetic diversity Genetic variability Human genetic variation References Jump up ^ Darwin, 1845. Journal of researches into the natural history and geology of the countries visited during the voyage of H.M.S. Beagle round the world, under the Command of Capt. Fitz Roy, R.N. 2d edition. ^ Jump up to : Lars Feuk, Andrew R. Carson & Stephen W. Scherer ( February 2006 ). `` Structural variation in the human genome ''. Nature Reviews Genetics. 7 ( 2 ) : 85 -- 97. PMID 16418744. doi : 10.1038 / nrg1767. Jump up ^ Witzany G ( December 2006 ) Natural genome - editing competences of viruses. Acta Biotheor. 54 : 235 - 253. Further reading Mayr E. ( 1970 ) : Populations, species, and evolution -- An abridgment of Animal species and evolution. The Belknap Press of Harvard University Press, Cambridge, Massachusetts and London, England, ISBN 0 - 674 - 69013 - 3. Dobzhansky T. ( 1970 ) : Genetics of the evolutionary process. Columbia, New York, ISBN 0 - 231 - 02837 - 7. McGinley, Mark ; J. Emmett Duffy ( ed ). 2008. `` Genetic variation. '' In : Encyclopedia of Earth. Washington, D.C. : National Council for Science and the Environment. `` Genetic Variation '' in Griffiths, A.J.F. Modern Genetic Analysis, Vol 2., p. 7 `` How is Genetic Variation Maintained in Populations '' in Sadava, D. et al. Life : The Science of Biology, p. 456 Nevo, E. ; Beiles, A. `` Genetic variation in nature ''. Scholarpedia, 6 ( 7 ) : 8821. doi : 10.4249 / scholarpedia. 8821 Hedrick P. ( 2011 ) : Genetics of populations. Jones & Bartlett Learning, ISBN 978 - 0 - 7637 - 5737 - 3. Rieger R. Michaelis A., Green M.M. ( 1976 ) : Glossary of genetics and cytogenetics : Classical and molecular. Springer - Verlag, Heidelberg - New York, ISBN 3 - 540 - 07668 - 9 ; ISBN 0 - 387 - 07668 - 9. Griffiths, A.J.F. ( 1999 ). An Introduction to genetic analysis. W.H. Freeman, San Francisco, ISBN 0 - 7167 - 3520 - 2. Cavalli - Sforza L.L., Bodmer W.F. ( 1999 ) : The genetics of human populations. Dover, Mineola, New York, ISBN 0 - 486 - 40693 - 8. External links Genetic variation Retrieved from `` https://en.wikipedia.org/w/index.php?title=Genetic_variation&oldid=806729349 '' Categories : Population genetics Hidden categories : Articles needing additional references from November 2016 All articles needing additional references Talk Contents About Wikipedia Afrikaans Bosanski Dansk Deutsch Қазақша Македонски Bahasa Melayu Polski Русский Srpskohrvatski / српскохрватски ไทย Türkçe Українська Zazaki Edit links This page was last edited on 23 October 2017, at 20 : 12. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. 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Question: the ultimate source of new variation in nature is
Answer: mutation