Rimantadine - wikipedia Rimantadine Rimantadine Clinical data Trade names Flumadine AHFS / Drugs.com Monograph MedlinePlus a698029 Pregnancy category C ( United States ) Routes of administration Oral ATC code J05AC02 ( WHO ) Legal status Legal status US : ℞ - only Pharmacokinetic data Bioavailability well absorbed Protein binding 40 % Metabolism Hepatic hydroxylation and glucuronidation Biological half - life 25.4 ± 6.3 hours Excretion Renal Identifiers IUPAC name 1 - ( adamantan - 1 - yl ) ethan - 1 - amine CAS Number 13392 - 28 - 4 PubChem CID 5071 DrugBank DB00478 ChemSpider 4893 UNII 0T2EF4JQTU KEGG D08483 ChEMBL CHEMBL959 PDB ligand RIM ( PDBe, RCSB PDB ) Chemical and physical data Formula Molar mass 179.302 g / mol 3D model ( JSmol ) Interactive image Chirality Racemic mixture SMILES NC ( C ) C13CC2CC ( CC ( C1 ) C2 ) C3 InChI InChI = 1S / C12H21N / c1 - 8 ( 13 ) 12 - 5 - 9 - 2 - 10 ( 6 - 12 ) 4 - 11 ( 3 - 9 ) 7 - 12 / h8 - 11H, 2 - 7, 13H2, 1H3 Key : UBCHPRBFMUDMNC - UHFFFAOYSA - N ( verify ) Rimantadine ( INN, sold under the trade name Flumadine ) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influenza. Both rimantadine and the similar drug amantadine are derivates of adamantane. Rimantadine was approved by the Food and Drug Administration ( FDA ) in 1994. Rimantadine was approved for medical use in 1993. 100 % of seasonal H3N2 and 2009 pandemic flu samples tested have shown resistance to rimantadine and it is no longer recommended to prescribe for treatment of the flu. Contents 1 Medical use 2 Drug interactions 3 Side effects 4 History 5 See also 6 References 7 External links Medical use Rimantadine is believed to inhibit influenza 's viral replication, possibly by preventing the uncoating of the virus 's protective shells, which are the envelope and capsid. Genetic studies suggest that the virus M2 protein, an ion channel specified by virion M2 gene, plays an important role in the susceptibility of influenza A virus to inhibition by rimantadine. Resistance to rimantadine can occur as a result of amino acid substitutions at certain locations in the transmembrane region of M2. This prevents binding of the antiviral to the channel. Rimantadine, like its antiviral cousin amantadine, possesses some NMDA antagonistic properties and is used as an antiparkinsonic drug ( i.e., in the treatment of Parkinson 's disease ). However, in general, neither rimantadine nor amantadine is a preferred agent for this therapy and would be reserved for cases of the disease that are less responsive to front - line treatments. Drug interactions Taking paracetamol ( acetaminophen, Tylenol ) or acetylsalicylic acid ( aspirin ) while taking rimantadine is known to reduce the body 's uptake of rimantadine by approximately 12 %. Cimetidine also affects the body 's uptake of rimantadine. Side effects Rimantadine can produce gastrointestinal and central nervous system adverse effects. Approximately 6 % of patients ( compared to 4 % of patients taking a placebo ) reported side - effects at a dosage of 200 mg / d. Common side effects include : nausea upset stomach nervousness tiredness lightheadedness trouble sleeping difficulty concentrating History Rimantadine was discovered in 1963 and patented in 1965 in the USA by William W. Prichard in Du Pont & Co., Wilmington, Delaware ( patent on new chemical compound U.S. Patent 3,352,912, 1965 and on the first method of synthesis U.S. Patent 3,592,934, 1967 ). Prichard 's methods of synthesis of rimantadine from the corresponding ketone oxime were based on its reduction with lithium aluminum hydride. See also Adapromine Bromantane Memantine Tromantadine References Jump up ^ Govorkova EA, Fang HB, Tan M, Webster RG ( December 2004 ). `` Neuraminidase Inhibitor - Rimantadine Combinations Exert Additive and Synergistic Anti-Influenza Virus Effects in MDCK Cells ''. Antimicrobial Agents and Chemotherapy. 48 ( 12 ) : 4855 -- 63. PMC 529183. PMID 15561867. doi : 10.1128 / AAC. 48.12. 4855 - 4863.2004. Jump up ^ Long, Sarah S. ; Pickering, Larry K. ; Prober, Charles G. ( 2012 ). Principles and Practice of Pediatric Infectious Disease. Elsevier Health Sciences. p. 1502. ISBN 1437727026. Jump up ^ Antiviral Agents for the Treatment and Chemoprophylaxis of Influenza : Recommendations of the Advisory Committee on Immunization Practices ( ACIP ) Jump up ^ Jing X, Ma C, Ohigashi Y, et al. ( August 2008 ). `` Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton - selective ion channel ''. Proc. Natl. Acad. Sci. U.S.A. 105 ( 31 ) : 10967 -- 72. PMC 2492755. PMID 18669647. doi : 10.1073 / pnas. 0804958105. Jump up ^ `` fda.gov ''. Archived from the original on June 30, 2005. Retrieved 2008 - 11 - 05. Jump up ^ `` CDC - Influenza ( Flu ) Antivirals : Side - Effects REMOVED ! ''. Retrieved 2008 - 11 - 05. Jump up ^ US patent 3352912 to W.W. Prichard Jump up ^ United States Patent No 4551552 : Process for preparing rimantadine : Rimantadine and related compounds useful as antivirals were first described by Prichard in U.S. Pat. Nos. 3,352,912 and 3,592,934. Both patents describe the preparation of rimantadine from the corresponding ketone oxime by reduction with lithium aluminum hydride. Jump up ^ United States Patent No 4551552 : Process for preparing rimantadine Jump up ^ Zlydnikov, D.M. ; Kubar, O.I. ; Kovaleva, T.P. ; Kamforin, L.E. `` Study of Rimantadine in the USSR : A Review of the Literature ''. Clinical Infectious Diseases. 3 : 408 -- 421. doi : 10.1093 / clinids / 3.3. 408. External links U.S. FDA press release announcing rimantadine 's approval U.S. Center for Drug Evaluation and Research rimantadine description U.S. NIH rimantadine description U.S. CDC flu anti-viral treatment information RNA virus antivirals ( primarily J05, also S01AD and D06BB ) Hepatitis C NS3 / 4A protease inhibitors ( -- previr ) Asunaprevir Boceprevir Ciluprevir Danoprevir Faldaprevir Glecaprevir Grazoprevir Narlaprevir Paritaprevir Simeprevir Sovaprevir Telaprevir Vaniprevir Vedroprevir Voxilaprevir NS5A inhibitors ( -- asvir ) Daclatasvir Elbasvir Ledipasvir Odalasvir Ombitasvir Pibrentasvir Ravidasvir Ruzasvir Samatasvir Velpatasvir NS5B RNA polymerase inhibitors ( -- buvir ) Beclabuvir Dasabuvir Deleobuvir Filibuvir Setrobuvir Sofosbuvir Radalbuvir Uprifosbuvir Combination drugs Elbasvir / grazoprevir Glecaprevir / pibrentasvir Ledipasvir / sofosbuvir Ombitasvir / paritaprevir / ritonavir Sofosbuvir / daclatasvir Sofosbuvir / velpatasvir / voxilaprevir Velpatasvir / sofosbuvir Picornavirus viral entry : Pleconaril Anti-influenza agents Umifenovir adamantane derivatives / M2 inhibitors ( Adapromine Amantadine Rimantadine ) neuraminidase inhibitors / release phase ( Oseltamivir Zanamivir Peramivir, Laninamivir ) Multiple / general Interferon Interferon alfa 2b Peginterferon alfa - 2a Multiple / unknown BCX4430 Favipiravir GS - 5734 Mericitabine MK - 608 NITD008 Moroxydine Ribavirin / Taribavirin Triazavirin WHO - EM Withdrawn from market Clinical trials : Phase III Never to phase III Influenza General topics Research Vaccine Treatment Genome sequencing Reassortment Superinfection Flu season Viruses Orthomyxoviridae Influenza A Influenza B Influenza C Influenza A virus subtypes H1N1 H1N2 H2N2 H2N3 H3N1 H3N2 H3N8 H5N1 H5N2 H5N3 H5N6 H5N8 H5N9 H6N1 H7N1 H7N2 H7N3 H7N4 H7N7 H7N9 H9N2 H10N7 H1N1 Pandemics 1918 ( `` Spanish flu '' ) 2009 ( `` swine flu '' ) Science 2009 A / H1N1 H5N1 Outbreaks Croatia ( 2005 ) India ( 2006 ) UK ( 2007 ) West Bengal ( 2008 ) Science Genetic structure Transmission and infection Global spread Vaccine clinical trials Human mortality Social impact Pandemic preparation Treatments Antiviral drugs Adamantane derivatives Amantadine Rimantadine Neuraminidase inhibitor Oseltamivir Laninamivir Peramivir Zanamivir Peramivir ( experimental ) Umifenovir Vaccines Live attenuated influenza vaccine Fluzone Pandemrix Pandemics and epidemics Pandemics `` Russian flu '' ( 1889 -- 1890 ) `` Spanish flu '' ( 1918 ) `` Asian flu '' `` Hong Kong flu '' ( 1968 ) `` Swine flu '' ( 2009 ) Epidemics `` Russian flu '' ( 1977 -- 1978 ) `` Fujian flu '' ( H3N2 ) Central Luzon H5N6 ( 2017 ) Non-human Mammals Canine Feline Equine 2007 Australian outbreak Swine Non-mammals Avian Fujian ( H5N1 ) Complications Acute bronchitis Bronchiolitis Croup Otitis media Pharyngitis Pneumonia Sinusitis Strep throat Related topics Influenza - like illness Antiparkinson agents ( N04 ) Dopaminergics DA precursors Levodopa Melevodopa DA receptor agonists Apomorphine Bromocriptine Cabergoline Dihydroergocryptine Lisuride Pergolide Piribedil Pramipexole Ropinirole Rotigotine MAO - B inhibitors Rasagiline Selegiline COMT inhibitors Entacapone Opicapone Tolcapone AAAD inhibitors Benserazide Carbidopa Anticholinergics Benzatropine Biperiden Bornaprine Chlorphenoxamine Cycrimine Dexetimide Diphenhydramine Etanautine Etybenzatropine Mazaticol Metixene Orphenadrine Phenglutarimide Piroheptine Procyclidine Profenamine Trihexyphenidyl Tropatepine Others Amantadine Budipine Methylxanthines ( e.g., caffeine ) Rimantadine WHO - EM Withdrawn from market Clinical trials : Phase III Never to phase III Pharmacodynamics Dopamine receptor modulators D - like Agonists Benzazepines : 6 - Br - APB Fenoldopam SKF - 38,393 SKF - 77,434 SKF - 81,297 SKF - 82,958 SKF - 83,959 Trepipam Zelandopam Ergolines : Cabergoline CY - 208,243 Dihydroergocryptine LEK - 8829 Lisuride Pergolide Terguride Dihydrexidine derivatives : A-77636 A-86929 Adrogolide ( ABT - 431, DAS - 431 ) Dihydrexidine Dinapsoline Dinoxyline Doxanthrine Phenethylamines : BCO - 001 Deoxyepinephrine ( N - methyldopamine, epinine ) Dopexamine Etilevodopa Ibopamine L - DOPA ( levodopa ) Melevodopa L - Phenylalanine L - Tyrosine XP21279 Others : A-68930 Apomorphine Isocorypalmine Nuciferine PF - 6649751 PF 6669571 Propylnorapomorphine Rotigotine SKF - 89,145 SKF - 89,626 Stepholidine Tetrahydropalmatine Antagonists Typical antipsychotics : Butaclamol Chlorpromazine Chlorprothixene Flupentixol ( flupenthixol ) ( + melitracen ) Fluphenazine Loxapine Perphenazine ( + amitriptyline ) Pifluthixol Thioridazine Thiothixene Trifluoperazine ( + tranylcypromine ) Zuclopenthixol Atypical antipsychotics : Asenapine Clorotepine Clotiapine Clozapine DHA - clozapine Fluperlapine Iloperidone Norclozapine Norquetiapine Olanzapine ( + + fluoxetine ) Paliperidone Quetiapine Risperidone Tefludazine Zicronapine Ziprasidone Zotepine Others : Berupipam Ecopipam EEDQ Metitepine ( methiothepin ) Odapipam Perlapine SCH - 23390 D - like Agonists Adamantanes : Amantadine Memantine Rimantadine Aminotetralins : 5 - OH - DPAT 7 - OH - DPAT 8 - OH - PBZI Rotigotine UH - 232 Ergolines : Bromocriptine Cabergoline Dihydroergocryptine Epicriptine Lisuride LSD Pergolide Terguride Dihydrexidine derivatives : 2 - OH - NPA Ciladopa Dihydrexidine Dinoxyline N, N - Propyldihydrexidine Phenethylamines : Deoxyepinephrine ( N - methyldopamine, epinine ) Dopexamine Etilevodopa Ibopamine L - DOPA ( levodopa ) L - Phenylalanine L - Tyrosine Melevodopa XP21279 Atypical antipsychotics : Alentemol ( U-66444B ) Aripiprazole ( + sertraline ) Aripiprazole lauroxil Bifeprunox Brexpiprazole Cariprazine F - 15063 Lumateperone Norclozapine RP - 5063 Others : 3 - PPP A-412997 ABT - 670 ABT - 724 Adrafinil Aplindore Apomorphine Arketamine Armodafinil BP - 897 Captodiame CP - 226,269 Dizocilpine Esketamine Flibanserin GSK - 789,472 Ketamine Mesulergine Modafinil OSU - 6162 Pardoprunox PD - 128,907 PD - 168,077 PF - 219,061 PF - 592,379 Phencyclidine Piribedil Pramipexole Preclamol Propylnorapomorphine Pukateine Quinagolide Quinelorane Quinpirole RDS - 127 Ro10 - 5824 Ropinirole Roxindole Salvinorin A SKF - 83,959 Sumanirole Talipexole Umespirone WAY - 100,635 Antagonists Typical antipsychotics : Acepromazine Acetophenazine Azaperone Benperidol Bromperidol Butaclamol Butaperazine Chloracizine Chlorproethazine Chlorpromazine Chlorprothixene Ciclindole Clopenthixol Clothixamide Clopimozide Droperidol Fluacizine Fluanisone Flucindole Fluotracen Flupentixol ( flupenthixol ) ( + melitracen ) Fluphenazine Fluprothixene Fluspirilene Haloperidol Homopipramol Lenperone Levomepromazine ( methotrimeprazine ) Levosulpiride Loxapine Mesoridazine Moperone Naranol Nemonapride Penfluridol Perathiepin Perazine Pericyazine ( periciazine ) Perphenazine ( + amitriptyline ) Piflutixol ( pifluthixol ) Pimozide Pipamperone Preclamol Prochlorperazine Promazine Prothipendyl Spiperone ( spiroperidol ) Sulforidazine Sulpiride Sultopride Teflutixol Thiopropazate Thioproperazine Thioridazine Thiothixene Timiperone Trifluoperazine ( + tranylcypromine ) Triflupromazine Trifluperidol Zetidoline Zuclopenthixol Atypical antipsychotics : Amisulpride Asenapine BL - 1020 Blonanserin Carpipramine Cinuperone Clocapramine Clorotepine Clotiapine ( clothiapine ) Clozapine Cyamemazine DHA - clozapine Dixyrazine Elopiprazole Flumezapine Fluperlapine Gevotroline Iloperidone Lurasidone Mazapertine Melperone Molindone Mosapramine Ocaperidone Olanzapine ( + fluoxetine ) Paliperidone Perospirone Piperacetazine Pipotiazine Piquindone Quetiapine Remoxipride Risperidone Sertindole Tefludazine Tenilapine Tiospirone Veralipride Zicronapine Ziprasidone Zotepine Antiemetics / gastroprokinetics / sedatives : Aceprometazine AS - 8112 Alimemazine Alizapride Benzquinamide Bromopride Clebopride Domperidone Eticlopride Hydroxyzine Itopride Metoclopramide Metopimazine Promethazine Thiethylperazine Trimethobenzamide Antidepressants : Amoxapine Nefazodone Opipramol Propiomazine Trimipramine Others : 3 - PPP Azapride Buspirone Desmethoxyfallypride EEDQ F - 15063 Fallypride Fananserin Fenfluramine GSK - 789,472 Iodobenzamide Isocorypalmine L - 741,626 L - 745,870 Levofenfluramine LEK - 8829 Metergoline Metitepine ( methiothepin ) N - Methylspiperone Nafadotride Nuciferine PNU - 99,194 Pridopidine Raclopride Sarizotan SB - 277,011 - A Seridopidine Sonepiprazole Spiroxatrine Stepholidine SV - 293 Tetrahydropalmatine Tiapride UH - 232 Yohimbine See also : Receptor / signaling modulators Adrenergics Serotonergics Monoamine reuptake inhibitors Monoamine releasing agents Monoamine metabolism modulators Monoamine neurotoxins Ionotropic glutamate receptor modulators AMPAR Agonists : Main site agonists : 5 - Fluorowillardiine Acromelic acid ( acromelate ) AMPA BOAA Domoic acid Glutamate Ibotenic acid Proline Quisqualic acid Willardiine ; Positive allosteric modulators : Aniracetam Cyclothiazide CX - 516 CX - 546 CX - 614 Farampator ( CX - 691, ORG - 24448 ) CX - 717 CX - 1739 CX - 1942 Diazoxide Hydrochlorothiazide ( HCTZ ) IDRA - 21 LY - 392098 LY - 395153 LY - 404187 LY - 451646 LY - 503430 Mibampator ( LY - 451395 ) Nooglutyl ORG - 26576 Oxiracetam PEPA PF - 04958242 Piracetam Pramiracetam S - 18986 Tulrampator ( S - 47445, CX - 1632 ) Antagonists : ACEA - 1011 ATPO Becampanel Caroverine CNQX Dasolampanel DNQX Fanapanel ( MPQX ) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel ( ACEA - 1021 ) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate YM90K Zonampanel ; Negative allosteric modulators : Barbiturates ( e.g., pentobarbital, sodium thiopental ) Cyclopropane Enflurane Ethanol ( alcohol ) Evans blue GYKI - 52466 GYKI - 53655 Halothane Irampanel Isoflurane Perampanel Pregnenolone sulfate Sevoflurane Talampanel ; Unknown / unsorted antagonists : Minocycline KAR Agonists : Main site agonists : 5 - Bromowillardiine 5 - Iodowillardiine Acromelic acid ( acromelate ) AMPA ATPA Domoic acid Glutamate Ibotenic acid Kainic acid LY - 339434 Proline Quisqualic acid SYM - 2081 ; Positive allosteric modulators : Cyclothiazide Diazoxide Enflurane Halothane Isoflurane Antagonists : ACEA - 1011 CNQX Dasolampanel DNQX GAMS Kaitocephalin Kynurenic acid Licostinel ( ACEA - 1021 ) LY - 382884 NBQX NS102 Selurampanel Tezampanel Theanine Topiramate UBP - 302 ; Negative allosteric modulators : Barbiturates ( e.g., pentobarbital, sodium thiopental ) Enflurane Ethanol ( alcohol ) Evans blue NS - 3763 Pregnenolone sulfate NMDAR Agonists : Main site agonists : AMAA Aspartate Glutamate Homocysteic acid ( L - HCA ) Homoquinolinic acid Ibotenic acid NMDA Proline Quinolinic acid Tetrazolylglycine Theanine ; Glycine site agonists : β - Fluoro - D - alanine ACBD ACC ( ACPC ) ACPD AK - 51 Apimostinel ( NRX - 1074 ) B6B21 CCG D - Alanine D - Cycloserine D - Serine DHPG Dimethylglycine Glycine HA - 966 L - 687414 L - Alanine L - Serine Milacemide Neboglamine ( nebostinel ) Rapastinel ( GLYX - 13 ) Sarcosine ; Polyamine site agonists : Neomycin Spermidine Spermine ; Other positive allosteric modulators : 24S - Hydroxycholesterol DHEA ( prasterone ) DHEA sulfate ( prasterone sulfate ) Epipregnanolone sulfate Pregnenolone sulfate SAGE - 718 Antagonists : Competitive antagonists : AP5 ( APV ) AP7 CGP - 37849 CGP - 39551 CGP - 39653 CGP - 40116 CGS - 19755 CPP Kaitocephalin LY - 233053 LY - 235959 LY - 274614 MDL - 100453 Midafotel ( d - CPPene ) NPC - 12626 NPC - 17742 PBPD PEAQX Perzinfotel PPDA SDZ - 220581 Selfotel ; Glycine site antagonists : 4 - Cl - KYN ( AV - 101 ) 5, 7 - DCKA 7 - CKA ACC ACEA - 1011 ACEA - 1328 Apimostinel ( NRX - 1074 ) AV - 101 Carisoprodol CGP - 39653 CNQX D - Cycloserine DNQX Felbamate Gavestinel GV - 196771 Harkoseride Kynurenic acid Kynurenine L - 689560 L - 701324 Licostinel ( ACEA - 1021 ) LU - 73068 MDL - 105519 Meprobamate MRZ 2 / 576 PNQX Rapastinel ( GLYX - 13 ) ZD - 9379 ; Polyamine site antagonists : Arcaine Co 101676 Diaminopropane Diethylenetriamine Huperzine A Putrescine ; Uncompetitive pore blockers ( mostly dizocilpine site ) : 2 - MDP 3 - HO - PCP 3 - MeO - PCE 3 - MeO - PCMo 3 - MeO - PCP 4 - MeO - PCP 8A - PDHQ 18 - MC α - Endopsychosin Alaproclate Alazocine ( SKF - 10047 ) Amantadine Aptiganel Argiotoxin - 636 Arketamine ARL - 12495 ARL - 15896 - AR ARL - 16247 Budipine Coronaridine Delucemine ( NPS - 1506 ) Dexoxadrol Dextrallorphan Dextromethadone Dextromethorphan Dextrorphan Dieticyclidine Diphenidine Dizocilpine Ephenidine Esketamine Etoxadrol Eticyclidine Fluorolintane Gacyclidine Ibogaine Ibogamine Indantadol Ketamine Ketobemidone Lanicemine Levomethadone Levomethorphan Levomilnacipran Levorphanol Loperamide Memantine Methadone Methorphan Methoxetamine Methoxphenidine Milnacipran Morphanol NEFA Neramexane Nitromemantine Noribogaine Norketamine Orphenadrine PCPr PD - 137889 Pethidine ( meperidine ) Phencyclamine Phencyclidine Propoxyphene Remacemide Rhynchophylline Rimantadine Rolicyclidine Sabeluzole Tabernanthine Tenocyclidine Tiletamine Tramadol ; Ifenprodil ( NR2B ) site antagonists : Besonprodil Buphenine ( nylidrin ) CO-101244 ( PD - 174494 ) Eliprodil Haloperidol Isoxsuprine Radiprodil ( RGH - 896 ) Rislenemdaz ( CERC - 301, MK - 0657 ) Ro 8 - 4304 Ro 25 - 6981 Safaprodil Traxoprodil ( CP - 101606 ) ; NR2A - selective antagonists : MPX - 004 MPX - 007 TCN - 201 TCN - 213 ; Cations : Hydrogen Magnesium Zinc ; Alcohols / volatile anesthetics / related : Benzene Butane Chloroform Cyclopropane Desflurane Diethyl ether Enflurane Ethanol ( alcohol ) Halothane Hexanol Isoflurane Methoxyflurane Nitrous oxide Octanol Sevoflurane Toluene Trichloroethane Trichloroethanol Trichloroethylene Urethane Xenon Xylene ; Unknown / unsorted antagonists : ARR - 15896 Bumetanide Caroverine D - αAA Dexanabinol Flufenamic acid Flupirtine FPL - 12495 FR - 115427 Furosemide Hodgkinsine Ipenoxazone ( MLV - 6976 ) MDL - 27266 Metaphit Minocycline MPEP Niflumic acid Pentamidine Pentamidine isethionate Piretanide Psychotridine Transcrocetin ( saffron ) See also : Receptor / signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism / transport modulators Retrieved from `` https://en.wikipedia.org/w/index.php?title=Rimantadine&oldid=799954971 '' Categories : Adamantanes Amines Anti-influenza agents Suspected embryotoxicants Suspected teratogens NMDA receptor antagonists Proton channel blockers Hidden categories : Template : drugs.com link with non-standard subpage Drugboxes which contain changes to watched fields Talk Contents About Wikipedia Čeština Deutsch Español Esperanto Français Latviešu Polski Português Русский Slovenščina Српски / srpski Srpskohrvatski / српскохрватски Suomi Svenska ไทย Українська 中文 Edit links This page was last edited on 10 September 2017, at 20 : 25. 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Question: an antiviral drug that is also used in the treatment of parkinson's disease is
Answer: Rimantadine