Pathogenesis - wikipedia Pathogenesis Not to be confused with Parthenogenesis or Palingenesis. The pathogenesis of a disease is the biological mechanism ( or mechanisms ) that leads to the diseased state. The term can also describe the origin and development of the disease, and whether it is acute, chronic, or recurrent. The word comes from the Greek πάθος pathos ( `` disease '' ) and γένεσις genesis ( `` creation '' ). Contents 1 Description 2 See also 3 References 4 Further reading Description Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. For example, bacterial pathogenesis is the mechanism by which bacteria cause infectious illness. Most diseases are caused by multiple processes. For example, certain cancers arise from dysfunction of the immune system ( skin tumors and lymphoma after a renal transplant, which requires immunosuppression ). The pathogenic mechanisms of a disease ( or condition ) are set in motion by the underlying causes, which if controlled would allow the disease to be prevented. Often, a potential cause is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease. The pathological perspective can be directly integrated into an epidemiological approach in the interdisciplinary field of molecular pathological epidemiology. Molecular pathological epidemiology can help to assess pathogenesis and causality by means of linking a potential risk factor to molecular pathologic signatures of a disease. Thus, the molecular pathological epidemiology paradigm can advance the area of causal inference. See also Causal inference Epidemiology Molecular pathological epidemiology Molecular pathology Pathology Pathophysiology Salutogenesis References Jump up ^ Fox A ( 2010 ). General aspects of bacterial pathogenesis. University of South Carolina School of Medicine : Microbiology and Immunology On - line Textbook. Jump up ^ Porta M, Greenland S, Hernán M, dos Santos Silva I, Last JM, eds. ( 2014 ). A dictionary of epidemiology ( 6th ed. ). Oxford : Oxford University Press. ISBN 9780199976737. Jump up ^ Last, JM, ed. ( 2000 ). A Dictionary of Epidemiology ( 4th ed. ). Oxford : Oxford University Press. p. 132. ISBN 978 - 0 - 19 - 977434 - 0. Jump up ^ Ogino S, Stampfer M ( 2010 ). `` Lifestyle factors and microsatellite instability in colorectal cancer : the evolving field of molecular pathological epidemiology ''. J. Natl. Cancer Inst. 102 ( 6 ) : 365 -- 7. doi : 10.1093 / jnci / djq031. PMC 2841039. PMID 20208016. Jump up ^ Ogino S, Chan AT, Fuchs CS, Giovannucci E ( 2011 ). `` Molecular pathological epidemiology of colorectal neoplasia : an emerging transdisciplinary and interdisciplinary field ''. Gut. 60 ( 3 ) : 397 -- 411. doi : 10.1136 / gut. 2010.217182. PMC 3040598. PMID 21036793. Further reading Medicine portal Haugan S, Bjornson W ( 2009 ). Avian influenza : etiology, pathogenesis, and interventions. Hauppauge, NY : Nova Science Publishers. ISBN 978 - 1 - 60741 - 846 - 7. Retrieved from `` https://en.wikipedia.org/w/index.php?title=Pathogenesis&oldid=811502406 '' Categories : Pathology Talk Contents About Wikipedia Български Čeština Deutsch Español Euskara فارسی Français Հայերեն Bahasa Indonesia Italiano ქართული Қазақша Magyar Nederlands Norsk nynorsk Oʻzbekcha / ўзбекча Polski Português Русский Slovenčina Српски / srpski Svenska தமிழ் ไทย Türkçe Українська 18 more Edit links This page was last edited on 22 November 2017, at 01 : 32. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: the medical term pathogenesis is best defined as
Answer: the biological mechanism (or mechanisms) that leads to the diseased state