Purple drank - wikipedia Purple drank A spoonful of promethazine / ​ codeine syrup showing the characteristic purple color Purple drank is a slang term for a concoction which includes a prescription - strength cough syrup used in a manner inconsistent with its labeling, thus making it a recreational drug. The mixture became popular in the hip hop community in the southern United States in the 1990s, originating in Houston. The prescription - strength cough syrup used in purple drank contains codeine and promethazine ( not to be confused with dextromethorphan ; DXM ). The cough syrup, used in doses much higher than medically recommended, is typically mixed with ingredients such as the soft drinks Sprite or Mountain Dew and optionally `` a Jolly Rancher hard fruit candy thrown in for extra sweetness. '' The purplish hue of purple drank comes from dyes in the cough syrup. The amount of cough syrup used `` can exceed up to 25 times the recommended dose. '' The concoction is `` Typically consumed out of Styrofoam cups ''. There are numerous slang terms for purple drank, including sizzurp, lean, syrup, drank, barre, purple jelly, Texas tea, dirty Sprite, and Tsikuni. Contents 1 Effects 1.1 Hazards 2 History 2.1 Popularization 2.2 Notable deaths from use 2.3 Other notable incidents 3 Commercial products 3.1 Criticism 4 References Effects The physiological effects of purple drank on the user is to produce mild `` euphoric side effects '', which are accompanied by `` motor - skill impairment, lethargy, drowsiness, and a dissociative feeling from all other parts of the body ''. Houston author Lance Scott Walker noted that the super-sweet combination of soda, cough syrup, and Jolly Ranchers provides a flavor and mouthfeel which stays on the tongue for an extended duration. This phenomenon is often appealing to first - time users. Purple drank is often used in combination with alcohol and / or other drugs. Hazards In an article following the hospitalization of the rapper Lil Wayne alleged to be related to purple drank, the Los Angeles Times spoke to physician and hospitalist Dr. George Fallieras, on the hazards of the concoction. Fallieras stated that in its intended usage, `` The codeine in the medicine serves as a pain reliever and also suppresses coughing. A second drug in the cough syrup, known as promethazine, is used as an antihistamine and commonly used to treat motion sickness and nausea. It 's also a bit of a sedative -- employed partly to keep people from drinking too much of the stuff. This is a very common cough syrup that, when taken in appropriately prescribed quantities, is quite safe. '' Dangers arise in higher dosages because promethazine is a depressant of the central nervous system and codeine is a respiratory depressant. When codeine is taken in very large amounts, it can cause one to stop breathing. Using alcohol and other drugs alongside purple drank increases the chance of problems. Fallieras stated that the concoction does not cause seizures itself but increases their likelihood in those susceptible to them. The drink includes a `` massive '' amount of the opiate codeine, which can be addictive in high doses, and Fallieras states that `` promethazine has at least anecdotally been noted to intensify the euphoric effects of codeine in the brain. '' The addictive nature of the drink means that trying to discontinue regular usage can bring about symptoms of withdrawal. In a 2008 interview with MTV News, Lil Wayne described the withdrawal as feeling `` like death in your stomach when you stop. Everybody wants me to stop all this and all that. It ai n't that easy. '' History According to Houston - based author Lance Scott Walker, purple drank developed in that city around the 1960s when blues musicians would take Robitussin and cut it with beer. Later when wine coolers came onto the market, they substituted for beer. These blues musicians lived in Houston 's Fifth Ward, Third Ward, and South Park neighborhoods and the practice was taken up by the generation of rappers growing up in the same parts of the city. In the 1980s and 1990s the formula changed to using codeine promethazine cough syrup, lemon - lime - flavored soda, and Jolly Ranchers. Professor Ronald Peters, also a Houston resident, points out that purple drank remained a local Houston phenomenon until the 1990s rapper DJ Screw released several tunes mentioning the drink in his mixtapes which were extremely popular in the Houston area. Walker holds that DJ Screw 's music was particularly appropriate for Houston 's climate. Due to the heat and expanse of the Houston area residents spent long drives in their cars, `` the music that most appropriately complements that has always been the music of DJ Screw, it 's slowed down -- and when I say slowed down I mean he would record sessions in his apartment with rappers freestyling over beats and he would make these big mixtapes and then he would actually slow them down even further on his cassette recorder. '' DJ Screw 's invoking purple drank in his lyrics and his use of slow tempos had caused his style to be characterized `` ( a ) s if the song itself has taken too much codeine promethazine ''. Rappers outside of Houston soon adopted aspects of his style. Walker points out that purple drank had never been stigmatized in Houston, but with the apparently purple drank related early death of DJ Screw, the concoction became the focus of law enforcement in the Houston area with felony charges being applied for some aspects surrounding it. Popularization Houston producer DJ Screw popularized the concoction, which is widely attributed as a source of inspiration for the `` chopped and screwed '' style of hip hop music. The promethazine and codeine concoction first gained popularity in the underground rap scene in Houston, where musician Big Hawk said it was consumed as early as the 1960s and 1970s, becoming more widely used in the early 1990s. Because of usage by rap artists in Houston, it became more popular in the 1990s. Its use later spread to other southern states. In June 2000, Three 6 Mafia 's single `` Sippin ' on Some Syrup '', featuring UGK, brought the term `` purple drank '' to a nationwide audience. In 2004, the University of Texas found that 8.3 % of secondary school students in Texas had taken codeine syrup to get high. The Drug Enforcement Administration reports `` busts '' involving syrup across the southern United States, particularly in Texas and Florida. As of 2011, the price of purple drank in Houston is twice the price as it is in Los Angeles. Notable deaths from use Purple drank is confirmed or suspected to have caused the deaths of several prominent users. Respiratory depression is a potentially serious or fatal adverse drug reaction associated with the use of codeine, but mainly the danger lies in the much more potent and CNS - depressing phenothiazine - related antihistamine promethazine. This depression is dose - related and is the mechanism for the potentially fatal consequences of overdose : respiratory or cardiac arrest. As with most CNS depressants, mixing with alcohol greatly increases the risk of respiratory failure and other complications. DJ Screw, who popularized the codeine - based drink, died of a codeine - promethazine - alcohol overdose on November 16, 2000, several months after the video to Three 6 Mafia 's single debuted. Big Moe, a DJ Screw protégé whose albums City of Syrup and Purple World were based on the drink and who has been described as having `` rapped obsessively about the drug '', died at age 33 on October 14, 2007, after suffering a heart attack one week earlier that left him in a coma. There was speculation that purple drank may have contributed to his death. Pimp C, widely influential Port Arthur, Texas rapper and a member of rap duo UGK, was found dead on December 4, 2007, at the Mondrian Hotel in West Hollywood, California. The Los Angeles County Coroner 's Office reported that the rapper 's death was `` due to promethazine / codeine effects and other unestablished factors ''. Ed Winter, assistant chief of the Coroner 's Office, said the levels of the medication were elevated, but not enough to deem the death an overdose. However, Pimp C had a history of sleep apnea, a condition that causes one to stop breathing for short periods during sleep. A spokesman for the coroner 's office said that the combination of sleep apnea and cough medication probably suppressed Pimp C 's breathing long enough to bring on his death. Other notable incidents In September 2006, Terrence Kiel, a San Diego Chargers player, was arrested during practice for the possession with intent to sell prescription cough syrup for use in making the drink. Kiel was caught trying to ship a case of syrup to a friend via FedEx. Kiel was charged with two felony counts of transporting a controlled substance and three counts of possession for sale of a controlled substance. On July 8, 2008, Johnny Jolly, a Green Bay Packers player, was pulled over in his car for playing an excessive level of music in a nightclub parking lot. The officers found a Dr Pepper bottle in a holder next to two Styrofoam cups containing soda and ice. The officers said the cups and the bottle all emitted `` strong odors of codeine. '' The case was dismissed, but charges were refiled in December 2009 after the Houston Police Department acquired new equipment that allowed the police to test the evidence again. Jolly faced a possible maximum sentence of up to 20 years in jail, but as a first time offender he would be eligible for probation. On July 5, 2010, former Oakland Raiders quarterback JaMarcus Russell was arrested at his home in Mobile, Alabama, for possession of codeine syrup without a prescription. He was arrested as part of an undercover narcotics investigation. Russell was booked into city jail and released soon afterwards after making his bail. On March 15, 2013, Lil Wayne was hospitalized with seizures allegedly after taking the drug Fellow rapper Birdman, however denied that the seizures were in any way connected to drugs. On June 11, 2013, just days after being robbed at gunpoint in San Francisco, rapper 2 Chainz was arrested at Los Angeles International Airport on charges of possessing promethazine and codeine ( the primary ingredients of purple drank ) along with marijuana. Commercial products Advertising for one commercial product with marketing based on purple drank. Several legal commercial products loosely based on the concept of `` purple drank '' are marketed in the United States. In June 2008, Innovative Beverage Group, a Houston, Texas - based company, released a beverage called `` Drank ''. The commercial product contains no codeine or promethazine, but claims to `` Slow Your Roll '' with a combination of herbal ingredients such as valerian root and rose hips as well as the hormone melatonin. Similar `` anti-energy '' or relaxation drinks on the commercial market use the names `` Purple Stuff '', `` Sippin Syrup '', and `` Lean ''. Criticism These commercial products have been criticized for their potential to serve as gateways to the dangerous illegal concoction. At a mental health conference in February 2010, Dr. Ronald Peters, Jr., of the University of Texas Health Science Center said of `` Drank '' : `` They 're taking the name, and they 're trying to market it to young people. '' He described the beverage as `` the worst thing I 've ever seen on the street since the making of candy cigarettes ''. References Houston portal Hip hop portal ^ Jump up to : Tamara Palmer ( 2005 ). Country Fried Soul : Adventures in Dirty South Hip - hop. Outline Press Limited. p. 188. Jump up ^ Peters Ronald J. Jr ; Steven H. Kelder ; Christine M. Markham ; George S. Yacoubian Jr ; Lecresha A. Peters ; Artist Ellis ( 2003 ). `` Beliefs and social norms about codeine and promethazine hydrochloride cough syrup ( CPHCS ) onset and perceived addiction among urban Houstonian adolescents : an addiction trend in the city of lean. ''. Journal of drug education. 33 ( 4 ) : 415 -- 25. PMID 15237866. doi : 10.2190 / NXJ6 - U60J - XTY0 - 09MP. ^ Jump up to : Melissa Leon ( March 17, 2013 ). `` Lil Wayne Hospitalization : What the Hell Is Sizzurp ? ''. The Daily Beast. ^ Jump up to : Bryan Robinson, Cough Syrup Abuse in Texas Takes Center Stage, ABC News, August 17, 2005 Jump up ^ Richard Klemme, USE OF PROMETHAZINE WITH CODEINE SYRUP : COUGH / COLD EPIDEMIC OR SIGNIFICANT ABUSE ?, Texas State Board of Pharmacy Newsletter, Volume XXV, Number 2, Spring 2001. The name `` lean '' refers to `` abusers ' propensity of having difficulty in standing up straight. '' Jump up ^ Shaheem Reid, Lil Wayne On Syrup : ' Everybody Wants Me To Stop... It Ai n't That Easy ', MTV.com, February 28, 2008 Jump up ^ http://www.wcyb.com/news/dirty-sprite-gains-popularity-among-teens/28236066 Jump up ^ Arizona Officer Safety Bulletin, ( 1 ), Public Intelligence, June 24, 2011 ^ Jump up to : Marah Eakin ( March 26, 2013 ). `` Learn all about the long, lean history of `` sizzurp '' with this 7 - minute audio primer ``. A.V. Club. ^ Jump up to : Amina Khan ( March 18, 2013 ). `` Doctor explains sizzurp 's powerful high -- and deadly side effects ''. Jump up ^ Allison Samuels ( March 18, 2013 ). `` Rapper Lil Wayne and His Struggle With Sizzurp ' Drank ' ''. ^ Jump up to : Leinwand, Donna ( 2006 - 10 - 18 ). `` DEA warns of soft drink - cough syrup mix ''. USA Today. Retrieved 2006 - 10 - 23. ^ Jump up to : ( 2 ) Corcoran, Michael Joseph ( 2005 ). `` The Geto Boys and DJ Screw : Where the Dirty South Began ''. All Over the Map : True Heroes of Texas Music ( 1st ed. ). Austin : University of Texas Press. pp. 23 -- 26. ISBN 0 - 292 - 70976 - 5. Jump up ^ Joseph Patel, Chopped & Screwed : A History, page 2, MTV.com. Accessed January 7, 2010. ^ Jump up to : Schiller, Dane. `` Purple Drank scheme allegedly made millions for smuggling ring. '' Houston Chronicle. Wednesday October 19, 2011. Retrieved on October 23, 2011. Jump up ^ Walker, Yolanda ( 2006 - 10 - 20 ). `` Drug - laced cough syrup tempts Texas teens ''. WFAA. Archived from the original on 2007 - 01 - 25. Retrieved 2006 - 10 - 28. Jump up ^ `` Alcohol Interactions with Other Drugs ''. Alcohol and Other Drugs Program Public Health Division, Health Department of Western Australia. 1999. Jump up ^ Demby, Eric ( 2001 - 01 - 11 ). `` Codeine Overdose Killed DJ Screw, Medical Examiner Says ''. MTV.com. Retrieved 2006 - 10 - 28. ^ Jump up to : Kristie Rieken, Cough syrup found in Pimp C 's hotel had no label, Associated Press, February 5, 2008 Jump up ^ DJs -- Rapper Big Moe Dies, contactmusic.com, 15 / 10 / 2007 Jump up ^ Leslie Casimir, Rapper 's death leads teens to re-evaluate lifestyle ; Fans and friends wonder whether drug was a factor in his heart attack, Houston Chronicle, Oct. 20, 2007 Jump up ^ Houston rappers remember Big Moe, by Eyder Peralta, Houston Chronicle, Oct. 16, 2007 Jump up ^ `` Cough syrup cited in rapper Pimp C 's death ''. LATimes.com. 2008 - 02 - 05. Retrieved 2008 - 03 - 15. Jump up ^ Chargers safety Kiel arrested on drug charges, USA Today, September 28, 2006 Jump up ^ Jolly faces unclear future -- Trial on felony charge of drug possession awaits Packers defensive lineman, Milwaukee Journal Sentinel, July 11, 2009. Jump up ^ Case against Jolly dismissed, `` Milwaukee Journal Sentinel '', July 16, 2009 Jump up ^ `` 540 ESPN Milwaukee ''. Espnmilwaukee.com. Retrieved 2010 - 01 - 04. Jump up ^ 2010 - 07 - 05 Archived July 8, 2010, at the Wayback Machine. Jump up ^ `` Lil Wayne Hospitalized - In Critical Condition After More Seizures ''. TMZ.com. 2013 - 03 - 15. Retrieved 2014 - 04 - 10. Jump up ^ Billboard Staff ( 18 March 2013 ). `` Lil Wayne 's Seizure Had ' Nothing to Do With Drugs, ' Says Birdman ''. billboard. Retrieved 22 February 2017. Jump up ^ `` 2013 - 11 - 06 ''. News.radio.com. 2013 - 06 - 11. Retrieved 2014 - 04 - 10. Jump up ^ `` ' Slow Your Roll ' With DRANK From Innovative Beverage Group -- the World 's First Extreme Lifestyle Relaxation Beverage ''. Yahoo. 2008 - 06 - 10. Archived from the original on December 2, 2008. Retrieved 2008 - 09 - 16. Jump up ^ Adventures in Press Releases : The Anti-Energy Drink By Sarah DiGregorio in Edible News, June 4, 2008 Jump up ^ ' Sippin Syrup ' being sold in stores creates controversy, theGrio website, 09 / 25 / 2009. Retrieved November 27, 2009. ^ Jump up to : Jemimah Noonoo, Anti-Energy Drink Fuels Concerns Over Marketing, Houston Chronicle, November 28, 2008 ; retrieved from commercialalert.org website on November 27, 2009 ^ Jump up to : Boyce Watkins, Company Makes Money from Deadly Urban Trend : `` Sipping Syrup '', AOL Black Voices, September 29, 2009 ^ Jump up to : Kim Horner, Anti-energy drink hard for some mental health experts to swallow, Dallas Morning News, February 18, 2010 Recreational drug use Major recreational drugs Depressants Barbiturates Benzodiazepines Carbamates Ethanol ( alcohol ) Alcoholic drinks Beer Wine Gabapentinoids GHB Inhalants Medical Nitrous oxide Hazardous solvents contact adhesives Gasoline nail polish remover Paint thinner Other Freon Kava Nonbenzodiazepines Quinazolinones Opioids Buprenorphine Suboxone Subutex Codeine Desomorphine Krokodil Dextropropoxyphene Darvocet Darvon Fentanyl Diamorphine Heroin Hydrocodone Hydromorphone Dilaudid Methadone Mitragyna speciosa Kratom Morphine Opium Oxycodone / paracetamol Tramadol Stimulants Amphetamine Arecoline Areca Betel Caffeine Coffee Energy drinks Tea Cathinone Khat Cocaine Coca Crack Ephedrine Ephedra MDPV Mephedrone Methamphetamine Methylone Methylphenidate Modafinil Nicotine Tobacco Theobromine Cocoa Chocolate Entactogens MDA MDMA Ecstasy 2C - * series alpha - Methyltryptamine 6 - APB Benzofury Hallucinogens Psychedelics Bufotenin Psychoactive toads Vilca Yopo DMT Ayahuasca LSA LSD - 25 Mescaline Peruvian torch Peyote San Pedro Psilocybin / Psilocin Psilocybin mushrooms Dissociatives DXM Glaucine Inhalants Nitrous oxide alkyl nitrites poppers amyl nitrite Ketamine MXE Muscimol Amanita muscaria PCP Salvinorin A Salvia divinorum Deliriants Atropine and Scopolamine Atropa belladonna Datura Hyoscyamus niger Mandragora officinarum Dimenhydrinate Diphenhydramine Cannabinoids JWH - 018 THC Cannabis Hashish Hash oil Marijuana Oneirogens Calea zacatechichi Silene capensis Club drugs Cocaine Quaaludes MDMA ( Ecstasy ) Nitrous oxide Poppers Drug culture Cannabis culture 420 Cannabis cultivation Cannabis smoking Head shop Legal history of cannabis in the United States Legality of cannabis Marijuana Policy Project Medical cannabis NORML Cannabis and religion Stoner film Coffee culture Coffee break Coffeehouse Latte art Tea house Drinking culture Bartending Beer culture Beer festival Binge drinking Diethyl ether Drinking games Drinking song Happy hour Hip flask Nightclub Pub Pub crawl Sommelier Sports bar Tailgate party Wine bar Wine tasting Psychedelia Psychonautics Art Drug Era Experience Literature Music Therapy Smoking culture Cigarette card Fashion cigarettes Cloud - chasing Loosie Smokeasy Smoking fetishism Tobacco smoking Other Club drug Counterculture of the 1960s Dance party Drug paraphernalia Drug tourism Entheogen Hippie Nootropic Party and play Poly drug use Rave Religion and drugs Self - medication Sex and drugs Whoonga Drug production and trade Drug production Coca production in Colombia Drug precursors Opium production in Afghanistan Rolling meth lab Drug trade Illegal drug trade Colombia Darknet market Drug distribution Beer shop Cannabis shop Liquor store Liquor license Issues with drug use Abuse Date rape drug Impaired driving Drug harmfulness Effects of cannabis Addiction Dependence Prevention Opioid replacement therapy Rehabilitation Responsible use Drug - related crime Fetal alcohol spectrum disorder Long - term effects of cannabis Neurotoxicity Overdose Passive smoking of tobacco or other substances Legality of drug use International 1961 Narcotic Drugs 1971 Psychotropic Substances 1988 Drug Trafficking Council of the European Union decisions on designer drugs State level Drug policy Decriminalization Prohibition Supply reduction Policy reform Demand reduction Drug Policy Alliance Harm reduction Law Enforcement Action Partnership Liberalization Latin America Students for Sensible Drug Policy Transform Drug Policy Foundation Drug policy by country Australia Canada Germany India Netherlands Portugal Slovakia Soviet Union Sweden Switzerland United States Just Say No Office of National Drug Control Policy School district drug policies California Colorado Maryland Virginia Other Arguments for and against drug prohibition Capital punishment for drug trafficking Cognitive liberty Designer drug Drug court Drug possession Drug test Narc Politics of drug abuse War on Drugs Mexican Drug War Plan Colombia Philippine Drug War Zero tolerance Lists of countries by... Alcohol legality Alcohol consumption Anabolic steroid legality Cannabis legality Annual use Lifetime use Cigarette consumption Cocaine legality Cocaine use Methamphetamine legality Opiates use Psilocybin mushrooms legality Salvia legality Acetylcholine receptor modulators Muscarinic acetylcholine receptor modulators mAChRs Agonists 77 - LH - 28 - 1 AC - 42 AC - 260,584 Aceclidine Acetylcholine AF30 AF150 ( S ) AF267B Alvameline AQRA - 741 Arecoline Bethanechol Bevonium Butyrylcholine Carbachol CDD - 0034 CDD - 0078 CDD - 0097 CDD - 0098 CDD - 0102 Cevimeline Choline cis - Dioxolane Clozapine Desmethylclozapine ( norclozapine ) Ethoxysebacylcholine Itameline LY - 593,039 L - 689,660 LY - 2,033,298 McNA343 Methacholine Milameline Muscarine NGX - 267 Ocvimeline Oxotremorine PD - 151,832 Pilocarpine RS86 Sabcomeline SDZ 210 - 086 Sebacylcholine Suberyldicholine Talsaclidine Tazomeline Thiopilocarpine Vedaclidine VU - 0029767 VU - 0090157 VU - 0152099 VU - 0152100 VU - 0238429 WAY - 132,983 Xanomeline YM - 796 Antagonists 3 - Quinuclidinyl benzilate 4 - DAMP Aclidinium bromide ( + formoterol ) Abediterol AF - DX 250 AF - DX 384 Ambutonium bromide Anisodamine Anisodine Antihistamines ( first - generation ) ( e.g., brompheniramine, buclizine, captodiame, chlorphenamine ( chlorpheniramine ), cinnarizine, clemastine, cyproheptadine, dimenhydrinate, dimetindene, diphenhydramine, doxylamine, meclizine, mepyramine ( pyrilamine ), mequitazine, perlapine, phenindamine, pheniramine, phenyltoloxamine, promethazine, propiomazine, triprolidine ) AQ - RA 741 Atropine Atropine methonitrate Atypical antipsychotics ( e.g., clozapine, fluperlapine, olanzapine ( + fluoxetine ), rilapine, quetiapine, tenilapine, zotepine ) Benactyzine Benzatropine ( benztropine ) Benzilone Benzilylcholine mustard Benzydamine BIBN 99 Biperiden Bornaprine Camylofin CAR - 226,086 CAR - 301,060 CAR - 302,196 CAR - 302,282 CAR - 302,368 CAR - 302,537 CAR - 302,668 Caramiphen Cimetropium bromide Clidinium bromide Cloperastine CS - 27349 Cyclobenzaprine Cyclopentolate Darifenacin DAU - 5884 Desfesoterodine Dexetimide DIBD Dicycloverine ( dicyclomine ) Dihexyverine Difemerine Diphemanil metilsulfate Ditran EA - 3167 EA - 3443 EA - 3580 EA - 3834 Emepronium bromide Etanautine Etybenzatropine ( ethybenztropine ) Fenpiverinium Fentonium Fesoterodine Flavoxate Glycopyrronium bromide ( + beclometasone / formoterol, + indacaterol ) Hexahydrodifenidol Hexahydrosiladifenidol Hexbutinol Hexocyclium Himbacine HL - 031,120 Homatropine Imidafenacin Ipratropium bromide ( + salbutamol ) Isopropamide J - 104,129 Hyoscyamine Mamba toxin 3 Mamba toxin 7 Mazaticol Mebeverine Meladrazine Mepenzolate Methantheline Methoctramine Methylatropine Methylhomatropine Methylscopolamine Metixene Muscarinic toxin 7 N - Ethyl - 3 - piperidyl benzilate N - Methyl - 3 - piperidyl benzilate Nefopam Octatropine methylbromide ( anisotropine methylbromide ) Orphenadrine Otenzepad ( AF - DX 116 ) Otilonium bromide Oxapium iodide Oxitropium bromide Oxybutynin Oxyphencyclimine Oxyphenonium bromide PBID PD - 102,807 PD - 0298029 Penthienate Pethidine pFHHSiD Phenglutarimide Phenyltoloxamine Pipenzolate bromide Piperidolate Pirenzepine Piroheptine Pizotifen Poldine Pridinol Prifinium bromide Procyclidine Profenamine ( ethopropazine ) Propantheline bromide Propiverine Quinidine Revefenacin Rociverine RU - 47,213 SCH - 57,790 SCH - 72,788 SCH - 217,443 Scopolamine ( hyoscine ) Scopolamine butylbromide ( hyoscine butylbromide ) Silahexacyclium Sofpironium bromide Solifenacin SSRIs ( e.g., femoxetine, paroxetine ) Telenzepine Terodiline Tetracyclic antidepressants ( e.g., amoxapine, maprotiline, mianserin, mirtazapine ) Tiemonium iodide Timepidium bromide Tiotropium bromide Tiquizium bromide Tofenacin Tolterodine Tricyclic antidepressants ( e.g., amitriptyline ( + perphenazine ), amitriptylinoxide, butriptyline, cidoxepin, clomipramine, desipramine, desmethyldesipramine, dibenzepin, dosulepin ( dothiepin ), doxepin, imipramine, lofepramine, nitroxazepine, northiaden ( desmethyldosulepin ), nortriptyline, protriptyline, quinupramine, trimipramine ) Tridihexethyl Trihexyphenidyl Trimebutine Tripitamine ( tripitramine ) Tropacine Tropatepine Tropicamide Trospium chloride Typical antipsychotics ( e.g., chlorpromazine, chlorprothixene, cyamemazine ( cyamepromazine ), loxapine, mesoridazine, thioridazine ) Umeclidinium bromide ( + vilanterol ) WIN - 2299 Xanomeline Zamifenacin Precursors ( and prodrugs ) Acetyl - coA Adafenoxate Choline ( lecithin ) Citicoline Cyprodenate Dimethylethanolamine Glycerophosphocholine Meclofenoxate ( centrophenoxine ) Phosphatidylcholine Phosphatidylethanolamine Phosphorylcholine Pirisudanol See also : Receptor / signaling modulators Nicotinic acetylcholine receptor modulators Acetylcholine metabolism / transport modulators Nicotinic acetylcholine receptor modulators nAChRs Agonists 5 - HIAA A-84,543 A-366,833 A-582,941 A-867,744 ABT - 202 ABT - 418 ABT - 560 ABT - 894 Acetylcholine Altinicline Anabasine Anatoxin - a AR - R17779 Bephenium hydroxynaphthoate Butinoline Butyrylcholine Carbachol Choline Cotinine Cytisine Decamethonium Desformylflustrabromine Dianicline Dimethylphenylpiperazinium Epibatidine Epiboxidine Ethanol ( alcohol ) Ethoxysebacylcholine EVP - 4473 EVP - 6124 Galantamine GTS - 21 Ispronicline Ivermectin Levamisole Lobeline MEM - 63,908 ( RG - 3487 ) Morantel Nicotine ( tobacco ) NS - 1738 PHA - 543,613 PHA - 709,829 PNU - 120,596 PNU - 282,987 Pozanicline Pyrantel Rivanicline RJR - 2429 Sazetidine A SB - 206553 Sebacylcholine SIB - 1508Y SIB - 1553A SSR - 180,711 Suberyldicholine Suxamethonium ( succinylcholine ) Suxethonium ( succinyldicholine ) TC - 1698 TC - 1734 TC - 1827 TC - 2216 TC - 5214 TC - 5619 TC - 6683 Tebanicline Tribendimidine Tropisetron UB - 165 Varenicline WAY - 317,538 XY - 4083 Antagonists 18 - MAC 18 - MC α - Neurotoxins ( e.g., α - bungarotoxin, α - cobratoxin, α - conotoxin, many others ) ABT - 126 Alcuronium Allopregnanolone Amantadine Anatruxonium AQW051 Atracurium Barbiturates ( e.g., pentobarbital, sodium thiopental ) BNC - 210 Bungarotoxins ( e.g., α - bungarotoxin, κ - bungarotoxin ) Bupropion BW - A444 Candocuronium iodide ( chandonium iodide ) Chlorisondamine Cisatracurium Coclaurine Coronaridine Curare Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine ( metocurine ) Dioscorine Dipyrandium Dizocilpine ( MK - 801 ) Doxacurium Encenicline Enflurane Erythravine Esketamine Fazadinium Gallamine Gantacurium chloride Halothane Hexafluronium Hexamethonium ( benzohexonium ) Hydroxybupropion Hydroxynorketamine Ibogaine Isoflurane Ketamine Kynurenic acid Laudanosine Laudexium ( laudolissin ) Levacetylmethadol Levomethadone Malouetine ME - 18 - MC Mecamylamine Memantine Methadone Methorphan ( racemethorphan ) Methyllycaconitine Metocurine Mivacurium Morphanol ( racemorphan ) Neramexane Nitrous oxide Norketamine Pancuronium bromide Pempidine Pentamine Pentolinium Phencyclidine Pipecuronium bromide Progesterone Promegestone Radafaxine Rapacuronium bromide Reboxetine Rocuronium bromide Sevoflurane Stercuronium iodide Surugatoxin Thiocolchicoside Toxiferine Tramadol Trimetaphan camsilate ( trimethaphan camsylate ) Tropeinium Tubocurarine Vanoxerine Vecuronium bromide Xenon Precursors ( and prodrugs ) Acetyl - coA Adafenoxate Choline ( lecithin ) Citicoline Cyprodenate Dimethylethanolamine Glycerophosphocholine Meclofenoxate ( centrophenoxine ) Phosphatidylcholine Phosphatidylethanolamine Phosphorylcholine Pirisudanol below = See also : Receptor / signaling modulators Muscarinic acetylcholine receptor modulators Acetylcholine metabolism / transport modulators ) ) Opioid receptor modulators MOR Agonists ( abridged ; see here for a full list ) : 3 - HO - PCP 7 - Acetoxymitragynine 7 - Hydroxymitragynine ψ - Akuammigine α - Chlornaltrexamine α - Narcotine Acetyldihydrocodeine Acetylfentanyl Acrylfentanyl Adrenorphin ( metorphamide ) AH - 7921 Akuammicine Akuammidine Alfentanil Anileridine Apparicine β - Endorphin BAM - 12P BAM - 18P BAM - 22P Benzhydrocodone Benzylmorphine Bezitramide Biphalin BU08070 Buprenorphine Butorphan Butorphanol Butyrfentanyl BW - 373U86 Carfentanil Casokefamide Cebranopadol Chloroxymorphamine Codeine DADLE DAMGO ( DAGO ) Dermorphin Desmetramadol ( desmethyltramadol ) Desomorphine Dextromoramide Dextropropoxyphene ( propoxyphene ) Dezocine Dimenoxadol Dimethylaminopivalophenone Eluxadoline Diamorphine ( heroin ) Dihydrocodeine Dihydroetorphine Dihydromorphine Diphenoxylate Dipipanone Dynorphin A Embutramide Endomorphin - 1 Endomorphin - 2 Eseroline Ethylmorphine Etorphine Fentanyl Fluorophen Frakefamide Furanylfentanyl Hemorphin - 4 Herkinorin Hodgkinsine Hydrocodone Hydromorphinol Hydromorphone IBNtxA Ketamine Ketobemidone Kratom Laudanosine Lefetamine Leu - enkephalin Levacetylmethadol Levomethorphan Levorphanol Lexanopadol Loperamide Loxicodegol Matrine Meptazinol Met - enkephalin ( metenkefalin ) Methadone Metkefamide Metopon Mitragynine Mitragynine pseudoindoxyl Morphiceptin Morphine Nalbuphine Nalbuphine sebacate NalBzOH Nalmexone Naltalimide Neopine NFEPP Nicocodeine Nicodicodeine Nicomorphine NKTR - 181 Norketamine Octreotide Oliceridine OM - 3 - MNZ Oripavine Oxycodone Oxymorphazone Oxymorphonazine Oxymorphone Oxymorphone phenylhydrazone OxyPNPH Papaver somniferum ( opium ) Pentazocine Pericine Pethidine ( meperidine ) Phenazocine Phencyclidine Piminodine Piritramide PL - 017 Prodine Propiram PZM21 Racemethorphan Racemorphan Remifentanil Salsolinol SC - 17599 Sinomenine Sufentanil Tapentadol Tetrahydropapaveroline TH - 030418 Thebaine Thienorphine Tianeptine Tilidine Tramadol Trimebutine TRIMU 5 TRV734 Tubotaiwine U-47700 Valorphin Viminol Xorphanol PAMs : BMS - 986121 BMS - 986122 Antagonists : ( 3S, 4S ) - Picenadol 2 - ( S ) - N, N - ( R ) - Viminol 3CS - nalmefene 4 - Caffeoyl - 1, 5 - quinide 4 ′ - Hydroxyflavanone 4 ', 7 - Dihydroxyflavone 6β - Naltrexol 6β - Naltrexol - d4 18 - MC α - Gliadin β - Chlornaltrexamine β - Funaltrexamine Akuammine Alvimopan AM - 251 Apigenin AT - 076 Axelopran Bevenopran Catechin Catechin gallate Clocinnamox CTAP CTOP Cyclofoxy Cyprodime Diacetylnalorphine Diprenorphine ECG EGC Epicatechin Eptazocine Gemazocine Ginsenoside R Hyperoside Ibogaine Levallorphan Lobeline LY - 255582 LY - 2196044 Methocinnamox Methylnaltrexone Methylsamidorphan chloride Naldemedine Nalmefene Nalodeine ( N - allylnorcodeine ) Nalorphine Nalorphine dinicotinate Naloxazone Naloxegol Naloxol Naloxonazine Naloxone Naltrexazone Naltrexonazine Naltrexone Naltrindole Naringenin Noribogaine Oxilorphan Pawhuskin A Rimonabant Quadazocine Samidorphan Taxifolin Unknown / unsorted : Cannabidiol Coronaridine Cyproterone acetate Dihydroakuuamine Tabernanthine Tetrahydrocannabinol DOR Agonists : 3CS - nalmefene 6 ' - GNTI 7 - SIOM ADL - 5747 ( PF - 04856881 ) ADL - 5859 Alazocine ( SKF - 10047 ) Amoxapine AR - M100390 ( ARM390 ) AZD2327 β - Endorphin BAM - 18P Biphalin BU - 48 Butorphan Butorphanol BW - 373U86 Casokefamide Cebranopadol Codeine Cyclazocine DADLE Deltorphin A Deltorphin I Deltorphin II Desmethylclozapine Desmetramadol ( desmethyltramadol ) Dezocine Diamorphine ( heroin ) Dihydroetorphine Dihydromorphine DPDPE DPI - 221 DPI - 3290 DSLET Ethylketazocine Etorphine Fentanyl FIT Fluorophen Hemorphin - 4 Hydrocodone Hydromorphone Ibogaine Isomethadone JNJ - 20788560 KNT - 127 Kratom Laudanosine Leu - enkephalin Levomethorphan Levorphanol Lexanopadol Lofentanil Met - enkephalin ( metenkefalin ) Metazocine Metkefamide Mitragynine Mitragynine pseudoindoxyl Morphine N - Phenethyl - 14 - ethoxymetopon Norbuprenorphine NalBzOH Oripavine Oxycodone Oxymorphone Pethidine ( meperidine ) Proglumide Racemethorphan Racemorphan RWJ - 394674 Samidorphan SB - 235863 SNC - 80 SNC - 162 TAN - 67 ( SB - 205,607 ) TH - 030418 Thebaine Thiobromadol ( C - 8813 ) Tonazocine Tramadol TRV250 Xorphanol Zenazocine Antagonists : 4 ', 7 - Dihydroxyflavone 5 ' - NTII 6β - Naltrexol 6β - Naltrexol - d4 α - Santolol β - Chlornaltrexamine Apigenin AT - 076 Axelopran Bevenopran BNTX Catechin Catechin gallate Clocinnamox Diacetylnalorphine Diprenorphine ECG EGC Eluxadoline Epicatechin ICI - 154129 ICI - 174864 LY - 255582 LY - 2196044 Methylnaltrexone Methylnaltrindole N - Benzylnaltrindole Nalmefene Nalorphine Naltrexone Naltriben Naltrindole Naloxone Naringenin Noribogaine Pawhuskin A Quadazocine SDM25N SoRI - 9409 Taxifolin Thienorphine Unknown / unsorted : 18 - MC Cannabidiol Coronaridine Cyproterone acetate Tabernanthine Tetrahydrocannabinol KOR Agonists : 3CS - nalmefene 6 ' - GNTI 8 - CAC 18 - MC 14 - Methoxymetopon β - Chlornaltrexamine β - Funaltrexamine Adrenorphin ( metorphamide ) Akuuamicine Alazocine ( SKF - 10047 ) Allomatrine Apadoline Asimadoline BAM - 12P BAM - 18P BAM - 22P Big dynorphin Bremazocine BRL - 52537 Butorphan Butorphanol BW - 373U86 Cebranopadol Ciprefadol CR665 Cyclazocine Cyclorphan Cyprenorphine Desmetramadol ( desmethyltramadol ) Diamorphine ( heroin ) Diacetylnalorphine Difelikefalin Dihydroetorphine Dihydromorphine Diprenorphine Dynorphin A Dynorphin B ( rimorphin ) Eluxadoline Enadoline Eptazocine Erinacine E Ethylketazocine Etorphine Fedotozine Fentanyl Gemazocine GR - 89696 GR - 103545 Hemorphin - 4 Herkinorin HS665 Hydromorphone HZ - 2 Ibogaine ICI - 199,441 ICI - 204,448 Ketamine Ketazocine Laudanosine Leumorphin ( dynorphin B - 29 ) Levallorphan Levomethorphan Levorphanol Lexanopadol Lofentanil LPK - 26 Lufuradom Matrine MB - 1C - OH Menthol Metazocine Metkefamide Mianserin Mirtazapine Morphine Moxazocine MR - 2034 N - MPPP Nalbuphine Nalbuphine sebacate NalBzOH Nalfurafine Nalmefene Nalodeine ( N - allylnorcodeine ) Nalorphine Naltriben Niravoline Norbuprenorphine Norbuprenorphine - 3 - glucuronide Noribogaine Norketamine Oripavine Oxilorphan Oxycodone Pentazocine Pethidine ( meperidine ) Phenazocine Proxorphan Racemethorphan Racemorphan RB - 64 Salvinorin A ( salvia ) Salvinorin B ethoxymethyl ether Salvinorin B methoxymethyl ether Samidorphan Spiradoline ( U-62,066 ) TH - 030418 Thienorphine Tifluadom Tricyclic antidepressants ( e.g., amitriptyline, desipramine, imipramine, nortriptyline ) U-50,488 U-54,494 A U-69,593 Xorphanol Antagonists : 4 ′ - Hydroxyflavanone 4 ', 7 - Dihydroxyflavone 5 ' - GNTI 6 ' - GNTI 6β - Naltrexol 6β - Naltrexol - d4 β - Chlornaltrexamine Buprenorphine / samidorphan Amentoflavone ANTI Apigenin Arodyne AT - 076 Axelopran AZ - MTAB Binaltorphimine BU09059 Buprenorphine Catechin Catechin gallate CERC - 501 ( LY - 2456302 ) Clocinnamox Cyclofoxy Dezocine DIPPA EGC ECG Epicatechin Hyperoside JDTic LY - 255582 LY - 2196044 LY - 2444296 LY - 2459989 LY - 2795050 MeJDTic Methylnaltrexone ML190 ML350 MR - 2266 N - Fluoropropyl - JDTic Naloxone Naltrexone Naltrindole Naringenin Norbinaltorphimine Noribogaine Pawhuskin A PF - 4455242 RB - 64 Quadazocine Taxifolin UPHIT Zyklophin Unknown / unsorted : Akuammicine Akuammine Coronaridine Cyproterone acetate Dihydroakuuamine Ibogamine Tabernanthine NOP Agonists : ( Arg14, Lys15 ) Nociceptin ( ( pF ) Phe ) Nociceptin ( 1 - 13 ) NH ( Phe Ψ ( CH - NH ) Gly ) Nociceptin ( 1 - 13 ) NH Ac - RYYRWK - NH Ac - RYYRIK - NH BU08070 Buprenorphine Cebranopadol Dihydroetorphine Etorphine JNJ - 19385899 Levomethorphan Levorphanol Levorphanol Lexanopadol MCOPPB MT - 7716 NNC 63 - 0532 Nociceptin ( orphanin FQ ) Nociceptin ( 1 - 11 ) Nociceptin ( 1 - 13 ) NH Norbuprenorphine Racemethorphan Racemorphan Ro64 - 6198 Ro65 - 6570 SCH - 221510 SCH - 486757 SR - 8993 SR - 16435 TH - 030418 Antagonists : ( Nphe ) Nociceptin ( 1 - 13 ) NH AT - 076 BAN - ORL - 24 J - 113397 JTC - 801 LY - 2940094 NalBzOH Nociceptin ( 1 - 7 ) Nocistatin SB - 612111 SR - 16430 Thienorphine Trap - 101 UFP - 101 Unsorted β - Casomorphins Amidorphin BAM - 20P Cytochrophin - 4 Deprolorphin Gliadorphin ( gluteomorphin ) Gluten exorphins Hemorphins Kava constituents MEAGL MEAP NEM Neoendorphins Nepetalactone ( catnip ) Peptide B Peptide E Peptide F Peptide I Rubiscolins Soymorphins Others Enkephalinase inhibitors : Amastatin BL - 2401 Candoxatril D - Phenylalanine Dexecadotril ( retorphan ) Ecadotril ( sinorphan ) Kelatorphan Racecadotril ( acetorphan ) RB - 101 RB - 120 RB - 3007 Opiorphan Selank Semax Spinorphin Thiorphan Tynorphin Ubenimex ( bestatin ) Propeptides : β - Lipotropin ( proendorphin ) Prodynorphin Proenkephalin Pronociceptin Proopiomelanocortin ( POMC ) Others : Kyotorphin ( met - enkephalin releaser / degradation stabilizer ) See also : Receptor / signaling modulators Signaling peptide / protein receptor modulators Retrieved from `` https://en.wikipedia.org/w/index.php?title=Purple_drank&oldid=805726991 '' Categories : Culture of Houston Culture of the Southern United States African - American culture Mixed drinks Drug culture Hypnotics Antitussives Opioids Hidden categories : Webarchive template wayback links Wikipedia indefinitely semi-protected pages Talk View source Contents About Wikipedia Deutsch Español فارسی Français Hrvatski Suomi Svenska Edit links This page was last edited on 17 October 2017, at 07 : 11. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: type of cough syrup used in purple drank
Answer: a prescription-strength cough syrup