Mitochondrial intermembrane space - Wikipedia Mitochondrial intermembrane space Simplified structure of mitochondrion This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. ( October 2017 ) The intermembrane space of a Mitochondrion refers to the compartment formed between the inner and outer mitochondrial membranes. The intermembrane space is chemically similar to cytosol, but includes a large amount of small proteins as well. As electrons move down the proteins in the electron transport chain, the electrons lose energy to bring H+ ions from the mitochondrial matrix into the intermembrane space. As a concentration gradient of hydrogen ions forms, a protein called ATP synthase harnesses the potential energy of these ions and starts chemiosmosis, where the H+ ions reenter the matrix via this enzyme bound to the cristae ( folds of the inner membrane ). ADP and a phosphate group are combined to form ATP. References Jump up ^ Alberts, B ; Johnson, A ; et al. ( 2002 ). Molecular Biology of the Cell. 4th edition. Garland Science. Mitochondrial proteins Outer membrane fatty acid degradation Carnitine palmitoyltransferase I Long - chain - fatty - acid -- CoA ligase tryptophan metabolism Kynureninase monoamine neurotransmitter metabolism Monoamine oxidase Intermembrane space Adenylate kinase Creatine kinase Inner membrane oxidative phosphorylation Coenzyme Q -- cytochrome c reductase Cytochrome c NADH dehydrogenase Succinate dehydrogenase pyrimidine metabolism Dihydroorotate dehydrogenase mitochondrial shuttle Malate - aspartate shuttle Glycerol phosphate shuttle other Glutamate aspartate transporter Glycerol - 3 - phosphate dehydrogenase ATP synthase Carnitine palmitoyltransferase II Uncoupling protein Matrix citric acid cycle Citrate synthase Aconitase Isocitrate dehydrogenase Oxoglutarate dehydrogenase complex Succinyl coenzyme A synthetase Fumarase Malate dehydrogenase anaplerotic reactions Aspartate transaminase Glutamate dehydrogenase Pyruvate dehydrogenase complex urea cycle Carbamoyl phosphate synthetase I Ornithine transcarbamylase N - Acetylglutamate synthase alcohol metabolism ALDH2 PMPCB Other / to be sorted steroidogenesis Cholesterol side - chain cleavage enzyme Steroid 11 - beta - hydroxylase Aldosterone synthase Frataxin Mitochondrial membrane transport protein Mitochondrial permeability transition pore Mitochondrial carrier Mitochondrial DNA Complex I MT - ND1 MT - ND2 MT - ND3 MT - ND4 MT - ND4L MT - ND5 MT - ND6 Complex III MT - CYB Complex IV MT - CO1 MT - CO2 MT - CO3 ATP synthase MT - ATP6 MT - ATP8 tRNA MT - TA MT - TC MT - TD MT - TE MT - TF MT - TG MT - TH MT - TI MT - TK MT - TL1 MT - TL2 MT - TM MT - TN MT - TP MT - TQ MT - TR MT - TS1 MT - TS2 MT - TT MT - TV MT - TW MT - TY see also mitochondrial diseases This biology article is a stub. You can help Wikipedia by expanding it. Retrieved from `` https://en.wikipedia.org/w/index.php?title=Mitochondrial_intermembrane_space&oldid=807942033 '' Categories : Cell anatomy Biology stubs Hidden categories : Articles needing additional references from October 2017 All articles needing additional references All stub articles Talk About Wikipedia Français 日本 語 中文 Edit links This page was last edited on 30 October 2017, at 23 : 32. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: where do h+ ions accumulate in the mitochondria
Answer: the intermembrane space