List of Spider - Man enemies - wikipedia List of Spider - Man enemies Depiction of the many Spider - Man villains in a dream sequence of Spider - Man in The Sensational Spider - Man ( vol. 2 ) # 32. Art by Sean Chen. ( Click on the character 's face to identify the character 's name and to learn more about the character. ) Spider - Man is a fictional superhero in the Marvel Universe debuting in the anthology comic book series issue Amazing Fantasy # 15 ( August 1962 ) in the Silver Age of Comics published by Marvel Comics. After his debut he would get his own comic book entitled The Amazing Spider - Man. The comic book series would introduce many of what would become his major supervillain adversaries. Spider - Man would then be popular enough for more Spider - Man comic spinoffs ( The Spectacular Spider - Man, Marvel Team - Up, Web of Spider - Man, Peter Parker : Spider - Man etc. ) which potentially introduced more recurring enemies of the web - slinger. As with Spider - Man, the theme behind the villains ' powers originate with scientific accidents or the misuse of scientific technology and also tend to have animal - themed costumes or powers ( Vulture, Doctor Octopus, Beetle, Lizard, Rhino, Scorpion, Kraven the Hunter, Jackal and Black Cat ). There also consists supervillains with the powers over the elements ( Sandman, Shocker, Electro, Molten Man and Hydro - Man ), some that are horror - themed ( the Goblins, Morbius, Morlun, and the Symbiotes ) and some that are crime lords ( Kingpin, Tinkerer, Tombstone, Hammerhead, Silvermane and Mister Negative ). His rogue also consisted of some that are masters of trickery and deception ( Chameleon and Mysterio ). These villains oftentimes form teams such as the Sinister Six to oppose the superhero. The rogues gallery of Spider - Man has garnered many positive reviews and has been considered as one of the greatest rogues gallery of all time by many alongside Batman 's rogues gallery. Contents 1 Debuting in Spider - Man titles 1.1 The Amazing Spider - Man debuts 1.2 The Spectacular Spider - Man debuts 1.3 Marvel Team - Up debuts 1.4 Debuting in other Spider - Man titles 2 Debuting outside Spider - Man titles 3 Reformed supervillain / anti-hero opponents 4 Non-supervillain enemies 5 Lesser foes 5.1 Delilah 5.2 Spidercide 6 Group villains 7 Archenemies 8 In other media 9 Reception 9.1 Themes 10 Notes 11 See also 12 References 13 External links Debuting in Spider - Man titles Stan Lee is responsible with helping create the most villains for the web - slinger and helped pave the way for the fictional rogues gallery. The majority of supervillains depicted in Spider - Man comics first appeared in The Amazing Spider - Man while some first appeared in later spinoff comics such as The Spectacular Spider - Man and Marvel Team - Up and other titles. The Amazing Spider - Man debuts See also : List of The Amazing Spider - Man issues Most of the supervillains of Spider - Man would be introduced in The Amazing Spider - Man comic book starting with the Chameleon. The early villains would be introduced in the 1960s in the Silver Age of Comic Books. Originally created by Stan Lee and Steve Ditko. John Romita, Sr. would soon replace Ditko starting with the Rhino. Gerry Conway later replaced Stan Lee and helped create new adversaries for the web - slinger and also helped pave the way to the Bronze Age of Comic Books with depicting Green Goblin as the killer of Spider - Man 's long time romantic interest, Gwen Stacy. Many collaborators would soon take over The Amazing Spider - Man title. One of the more popular examples included Todd McFarlane 's Venom in the Modern Age of Comic Books. Note : Alter ego characters who are the most high profile in the supervillain alias but others have shared that supervillain name are in bold. Alter egos listed having N / A use their real name as the supervillain name. In chronological order. Supervillain name Notable alter ego First appearance issue # Creator Chameleon Dmitri Anatoly Nikolayevich # 1 ( March 1963 ) Stan Lee Steve Ditko Vulture Adrian Toomes Blackie Drago # 2 ( May 1963 ) Stan Lee Steve Ditko Tinkerer Phineas Mason # 2 ( May 1963 ) Stan Lee Steve Ditko Doctor Octopus Doctor Otto Gunther Octavius # 3 ( July 1963 ) Stan Lee Steve Ditko Sandman William Baker / Flint Marko # 4 ( September 1963 ) Stan Lee Steve Ditko Lizard Doctor Curt Connors # 6 ( November 1963 ) Stan Lee Steve Ditko Living Brain N / A # 8 ( January 1964 ) Stan Lee Steve Ditko Electro Maxwell Dillon # 9 ( February 1964 ) Stan Lee Steve Ditko Big Man Frederick Foswell Janice Foswell # 10 ( March 1964 ) Stan Lee Steve Ditko Mysterio Quentin Beck # 13 ( June 1964 ) Stan Lee Steve Ditko Green Goblin Norman Osborn Harry Osborn # 14 ( July 1964 ) Stan Lee Steve Ditko Kraven the Hunter Sergei Kravinoff Alyosha Kravinoff ( son ) Ana Kravinoff ( daughter ) # 15 ( August 1964 ) Stan Lee Steve Ditko Scorpion Mac Gargan # 20 ( January 1965 ) Stan Lee Steve Ditko Spencer Smythe / Spider - Slayers Spencer Smythe : N / A Spider - Slayer : Multiple names # 25 ( June 1965 ) Stan Lee Steve Ditko Crime Master Various # 26 ( July 1965 ) Stan Lee Steve Ditko Molten Man Mark Raxton # 28 ( September 1965 ) Stan Lee Steve Ditko Looter Norton G. Fester # 36 ( May 1966 ) Stan Lee Steve Ditko Robot Master / Gaunt Mendel Stromm # 37 ( June 1966 ) Stan Lee Steve Ditko Rhino Aleksei Mikhailovich Sytsevich # 41 ( October 1966 ) Stan Lee John Romita, Sr. Shocker Herman Schultz # 46 ( March 1967 ) Stan Lee John Romita, Sr. Kingpin Wilson Fisk # 50 ( July 1967 ) ( `` Spider - Man No More ! '' ) Stan Lee John Romita, Sr. The Finisher Karl Fiers Annual # 5 ( November 1968 ) Stan Lee Larry Lieber Man Mountain Marko Michael Marko # 73 ( June 1969 ) Stan Lee John Romita, Sr. Silvermane Silvio Manfredi # 73 ( June 1969 ) Stan Lee John Buscema Kangaroo Frank Oliver Brian Hibbs # 81 ( February 1980 ) Stan Lee John Buscama Jim Mooney John Romita, Sr. Schemer Richard Fisk # 83 ( April 1983 ) Stan Lee John Romita, Sr. Morbius Michael Morbius # 101 ( January 1971 ) Roy Thomas Gil Kane Gog N / A # 103 ( December 1973 ) Roy Thomas Gil Kane Gibbon Martin Blank # 110 ( July 1972 ) Stan Lee John Romita, Sr. Hammerhead Joseph ( full name unknown ) # 113 ( October 10, 1972 ) Gerry Conway John Romita, Sr. Man - Wolf John Jameson # 124 ( September 1973 ). Gerry Conway Jackal Miles Warren # 129 ( February 1974 ) Gerry Conway Ross Andru Tarantula Various # 134 ( July 1974 ) Gerry Conway Ross Andru Mindworm William Turner # 138 ( November 1974 ) Gerry Conway Ross Andru Grizzly Maxwell Markham # 139 ( December 1974 ) Gerry Conway Ross Andru Human Fly Richard Deacon Annual # 10 ( 1976 ) Len Wein Bill Mantlo Gil Kane Will o ' the Wisp Jackson Arvad # 167 ( April 1977 ) Len Wein Ross Andru Big Wheel Jackson Wheele # 182 ( July 1978 ) Marv Wolfman Ross Andru Mike Esposito Black Cat Felicia Hardy # 194 ( July 1979 ) Marv Wolfman Keith Pollard Calypso Calypso Ezili # 209 ( October 1980 ) Dennis O'Neil Alan Weiss Hydro - Man Morris Bench # 212 ( January 10, 1981 ) Denny O'Neil John Romita, Jr. Hobgoblin Roderick Kingsley Jason Macendale Phil Urich # 238 ( March 1983 ) Roger Stern John Romita Sr. Rose Richard Fisk # 253 ( June 1984 ) Tom DeFalco Alistair Smythe N / A Annual # 19 ( November 1985 ) Louise Simonson Mary Wilshire Slyde Jalome Beacher # 272 ( January 1986 ) Tom DeFalco Sal Buscema Venom Eddie Brock Mac Gargan # 300 Todd McFarlane Styx and Stone Jacob Eishorn and Gerald Stone # 309 ( November 1988 ) David Michelinie Todd McFarlane Carnage Cletus Kasady # 361 ( April 1992 ) David Michelinie Erik Larsen Mark Bagley Black Tarantula Carlos LaMuerto # 419 ( January 1997 ) Tom DeFalco Steve Skroce Morlun N / A vol. 2 # 30 ( June 2001 ) J. Michael Straczynski John Romita, Jr. Shathra N / A vol. 2 # 46 ( December 2006 J. Michael Straczynski John Romita, Jr. Scott Hanna Grey Goblin Gabriel Stacy Lily Hollister ( Menace ) # 509 ( August 2004 ) # 550 ( April 2008 ) ( Menace ) J. Michael Straczynski Mike Deodato Mister Negative Martin Li # 546 ( January 2008 ) ( full appearance ) Dan Slott Phil Jimenez Overdrive N / A Swing Shift ( May 2007 ) Dan Slott Phil Jimenez Massacre Marcus Lyman # 655 ( April 2011 ) Dan Slott Marcos Martín The Spectacular Spider - Man debuts Note : In chronological order. Supervillain alter ego First appearance Carrion Various The Spectacular Spider - Man # 25 ( December 1978 ) Spot Jonathan Ohnn # 98 ( January 1985 ) Foreigner Kris Keating # 115 ( June 1986 ) Demogoblin N / A # 147 ( February 1989 ) ( as Hobgoblin ) Web of Spider - Man # 86 ( March 1992 ) Marvel Team - Up debuts Note : In chronological order. Supervillain alter ego First appearance creator Stegron Vincent Stegron Marvel Team - Up ( 1st series ) # 19 ( March 1974 ) Len Wein Gil Kane White Rabbit Doctor Lorina Dodson Marvel Team - Up # 131 ( July 1983 ) J.M. DeMatteis Kerry Gammill Mike Esposito Debuting in other Spider - Man titles Note : In chronological order. Supervillain alter ego First appearance creator Tombstone Lonnie Thompson Lincoln Web of Spider - Man # 36 ( March 1988 ) Gerry Conway Alex Saviuk Shriek Frances Louise Barrison Spider - Man Unlimited # 1 ( May 1993 ) Ron Lim Mark Bagley Mike W. Barr Tom DeFalco Jerry Bingham Terry Kavanagh Debuting outside Spider - Man titles Supervillain alter ego First appearance Beetle Abner Jenkins Strange Tales # 123 ( August 10, 1964 ) Boomerang Fred Myers Tales to Astonish # 81 ( July 10, 1966 ) Speed Demon James Sanders Avengers # 70 ( November 1969 ) ( as the Whizzer ) The Amazing Spider - Man # 222 ( November 1981 ) Ringer Anthony Davis Defenders # 51 ( June 1977 ) ) Swarm Fritz von Meyer Champions # 14 ( July 1977 ) Jack O'Lantern Jason Macendale Machine Man # 19 ( February 1981 ) Vermin Edward Whelan Captain America # 272 ( August 1982 ) Doppelganger N / A The Infinity War # 1 ( July 1992 ) Reformed supervillain / anti-hero opponents Almost all the characters listed first appeared in The Amazing Spider - Man with the exception of Kaine and Humbug first appearing in Web of Spider - Man. The Prowler is the oldest character appearing in The Amazing Spider - Man in the 1960s in the Silver Age. Many other anti-heroes were introduced in the 1970s in between the Silver Age and the Bronze Age while Humbug was introduced in the 1980s right around the start of the Modern Age. Kaine is the youngest debuted character while Cardiac is the second youngest. Both Kaine and Cardiac appeared around the 1990s. Anti-hero alter - ego First appearance Black Cat Felicia Hardy The Amazing Spider - Man # 194 ( July 1979 ) Cardiac Elias Wirtham The Amazing Spider - Man # 344 ( December 1990 ) Humbug Buck Mitty Web of Spider - Man # 19 ( October 1986 ) Kaine Kaine Parker Web of Spider - Man # 119 ( December 1994 ) Prowler Hobie Brown The Amazing Spider - Man # 78 ( November 1969 ) Puma Thomas Fireheart The Amazing Spider - Man # 256 ( September 1984 ) Punisher Frank Castle The Amazing Spider - Man # 129 ( February 1974 ) Rocket Racer Robert Farrell The Amazing Spider - Man # 172 ( September 1977 ) Non-supervillain enemies See also : List of Spider - Man supporting characters The Burglar and Flash Thompson both appeared in the first comic book starring Spider - Man appearing in the anthology series Amazing Fantasy. The certain comic book story inspired a comic book series entitled The Amazing Spider - Man which J. Jonah Jameson would appear in the first issue. All three of the characters listed appeared in the 1960s around the Silver Age of Comics. Human First appearance Detail Burglar Amazing Fantasy # 15 ( August 1962 ) The man who killed Peter 's uncle which would inspire Peter Parker to use his powers responsibly and become the superhero known as Spider - Man. Flash Thompson Amazing Fantasy # 15 ( August 1962 ) A sometimes enemy of Peter Parker instead of Spider - Man. Flash 's most common depiction is a high school bully of Parker commonly dubbing him `` Puny Parker ''. Despite how he treats Parker he happens to be one of Spider - Man 's biggest fan. Later on Flash would be depicted as being good friends to Peter instead. In The Amazing Spider - Man # 654, Flash Thompson becomes `` Agent Venom '' J. Jonah Jameson The Amazing Spider - Man # 1 ( March 1963 ) The editor in chief of The Daily Bugle. He has a strong hatred of Spider - Man so he helps turn the city against the superhero with the publishing of The Daily Bugle newspapers. He was also responsible for the funding of the creation of Scorpion and the Spider - Slayers. Lesser Foes Answer ( Aaron Nicholson ) Basilisk ( Basil Elks ) Black Fox ( Raul Chalmbers ) Chance ( Nicholas Powell ) Coldheart ( Kateri Deseronto ) Cyclone ( André Gerard ) Delilah First appearance The Spectacular Spider - Man # 414 ( August 1996 ) Created by Tom DeFalco and Mark Bagley Species Human Abilities Skilled at being an assassin. Further reading Delilah at the Comic Book DB Delilah at the Grand Comics Database Delilah first appeared in The Amazing Spider - Man # 414 by Tom DeFalco and Mark Bagley. The Rose 's confidante as well as his chief enforcer, Delilah helped battle to maintain control of part of the New York crime scene against the threat of the Black Tarantula. During her career, she had a role in the rebirth of two of Spider - Man 's old foes during the Rose 's efforts to gain extra muscle : she was the one who threw the switch of the electric chair which gave Electro his powers back, and helped set up the theft of Doctor Octopus ' corpse for re-animation from the Hand. She also appears in Loners as an assassin smuggling MGH. Spidercide First appearance The Spectacular Spider - Man # 22 ( March 1995 ) Created by Tom DeFalco and Sal Buscema Species Clone Abilities shapeshifting, molecular manipulation, same abilities of Spider - Man Aliases Peter Parker Spider - Man Freakface Further reading Spidercide at the Comic Book DB Spidercide at the Grand Comics Database Spidercide was a major antagonist in the Maximum Clonage story arc. He first appeared in The Spectacular Spider - Man # 222 by Tom DeFalco and Sal Buscema. He is depicted as an evil foil of Spider - Man, Ben Reilly, and Kaine. Introduced as a red herring to suggest the possibility of a third individual that was the original Peter Parker, he is one of the Spider - Man clones created by Jackal, to be Jackal 's enforcer and protector. However, Spidercide is actually a clone to Ben Reilly, who is a direct genetic duplicate of Spider - Man. He first appeared as a Peter Parker double emerging from one of the Jackal 's pods that initially an amnesiac but later believed himself to be the real Peter Parker, having been kept in stasis since the first Clone Saga. He claimed that both Peter Parker and Ben Reilly were his clones. However, upon meeting Parker, Reilly and Kaine, the Jackal 's programming kicked in and he went insane before shapeshifting into a freakish giant, and thus revealing his true status as a clone. In denial of the truth, he tried to kill the `` clones '' and to claim Peter Parker 's life as his own. He was even infatuated with Parker 's wife Mary Jane Watson and seeks to have her as his bride. Since their first encounter, Reilly realizes that Spidercide is twisted from the start and expresses disgust of his corrupted doppelgänger 's immorality, tauntingly refers him as `` Freakface '' once the villainous clone 's shapeshifting powers manifest. However, this also causes Reilly to be afraid of his and Parker 's capabilities for wicked if they allow themselves demoralize as Spidercide. The Jackal later modified Spidercide 's powers, granting him the unique ability to control his physical make - up on a molecular level ; he can alter his mass, density, shape and state at will similar to the symbiotes. He was killed off in Spider - Man : Maximum Clonage : Omega # 404 by being thrown off in the Daily Bugle. Group villains Cover of The Spectacular Spider - Man # 246 ( May 1997 ) depicting Spider - Man 's more weaker foes ( Spot, Gibbon, the second Kangaroo and the third Grizzly ) teaming up to try to defeat Spider - Man. Art by Luke Ross. Note : The common leader of the group is in bold. group name Original members Enforcers Montana Ox Fancy Dan Inheritors Solus Unnamed Matriarch Daemos Verna Karn Morlun Brix Bora Sinister Six Doctor Octopus Vulture Electro Sandman Mysterio Kraven the Hunter Spider - Man Revenge Squad Spot Grizzly Kangaroo II Gibbon Sinister Syndicate Beetle Hydro - Man Rhino Boomerang Speed Demon Archenemies Unlike well known rivalries in comics book depictions where heroes always still have more than one enemy but usually one archenemy ( e.g., Joker, to Batman in DC Comics, Red Skull to Captain America, Doctor Doom to the Fantastic Four and the Brotherhood of Mutants to the X-Men in Marvel Comics etc. ), Spider - Man is known to have three archenemies and it can be debated or disputed as to which one is worse : ^ Doctor Octopus is regarded as one of Spider - Man 's worst enemies. He has been cited as the man Peter might have become if he had n't been raised with a sense of responsibility. He is infamous for defeating him the first time in battle and for almost marrying Peter 's Aunt May. He is the core leader of the Sinister Six and has also referred himself as the `` Master Planner ''. ( `` If This Be My Destiny... ! '' ) Later depictions revealed him in Peter Parker 's body where he was the titular character for a while. ^ Norman Osborn using the alias as Green Goblin is Spider - Man 's archenemy. Mostly after he is responsible for setting up the death of Spider - Man 's girlfriend in one of the most famous Spider - Man stories of all time which helped end the Silver Age of Comic Books and begin the Bronze Age of Comic Books. He was thought to be dead after that but writers help bring him back from the 1990s and he returned to plague Spider - Man once more in the comic books ( such as being involved of the killing of Aunt May ) and other heroes ( such as the Avengers ). He is also an enemy of Spider - Man sometimes just as Norman and not just only as the Green Goblin. ^ Another character commonly described as archenemy is Venom. Eddie Brock as Venom is commonly described as the mirror version or the evil version of Spider - Man in many ways. Venom 's goals are usually depicted as ruining Spider - Man 's life and messing with Spider - Man 's head. Venom is also one of the most popular Spider - Man villains. This popularity has led him to be an established iconic character of his own with own comic book stories. In other media Main article : List of Spider - Man enemies in other media Reception Cosplay of Shocker, Rhino, Mysterio and Sandman Reaction to Spider - Man 's rogues gallery has been overwhelmingly positive with many journalists citing it as one of the greatest comic book rogues galleries of all time, with Batman 's rogues gallery being its most rivaled contender. Although editors such as The Hollywood Reporter 's Graeme McMillan felt that only Flash 's rogues gallery can compete with Spider - Man 's rogues. Kyle Schmidlin of What Culture ! described the superhero 's rogues gallery as `` one of the most colorful in comics '' explaining that Batman could only be debated as having a great number of enemies as good as Spider - Man. IGN staff editors, Joshua Yehl and Jesse Schedeen, described the Spider - Man villains as `` one of the most iconic and well - balanced in comics ''. They opined that the scope of their schemes, how cool their powers are, and how dramatically they have affected Spider - Man 's life is what makes the Spider - Man villains so great. Newsarama ranked Spider - Man 's rogues gallery as number one out ten as the greatest rogues gallery of all time. Themes George Marston of Newsarama explaining why he felt that Spider - Man rogues gallery was the best was the thematic elements that the villains of Spider - Man manifested. He explained that just like the superhero they have the same concept of science gone wrong. They are `` like him, great men with great minds, great power, and great determination. '' But instead they fail to use their powers responsibly. Separating the thin line between being a hero from being a villain. Notes ^ The Chameleon is the first member of Spider - Man 's rogues gallery in publication date. ( Excluding the Burglar ). He is also well known to be related to Kraven the Hunter and Kraven to him. That revealed relationship helped evolve him as a major villain compared to his original depiction of being just a solo villain in the original issue of The Amazing Spider - Man. ^ Besides being most notable as a Spider - Man supervillain. He has also been depicted as a Fantastic Four antagonist in Stan Lee and Jack Kirby comics books ( mostly due to being introduced as the original Frightful Four ) along with being on the heroic side ( being a Avengers member ) until being introduced as a tragic supervillain in the Spider - Man comics once again. ^ The character is also known as the member of the Frightful Four battling the Fantastic Four. He is also the first major Marvel villain to be written in publication history as battling Daredevil. Even being the founder and leader of the supervillain team that oppose him, the Emissaries of Evil. ^ Just like Electro. He has crossed over and been a major villain of Daredevil. In the storyline `` Guardian Devil '' he crossed into Daredevil 's territory almost pushing Daredevil to the edge ( just like what he is usually depicted as attempted to do in Spider - Man ) when Mysterio believes Spider - Man is a clone at one point. ^ Kraven the Hunter has been a recurring villain since his introduction as a Spider - Man villain. But what makes him stand out as one of the great Spider - Man villains along with being one of the memorable issues about the fictional villain in the Spider - Man comics is the critically acclaimed storyline, `` Kraven 's Last Hunt ''. ^ Not counting any other character in the mainstream Marvel Universe with that name. Only outside of the mainstream Spider - Man comics or in other media is there other Spider - Man villains ( that is n't named Mac Gargan ) that are antagonists of Spider - Man. Gargan is cited to be the fourth who is called that in the comic books but is the most iconic villain with that name. ^ The villain has crossed over with battling other heroes ( especially Hulk ) even though the fictional character is usually written off in Spider - Man comics. He is a major character in the storyline titled `` Flowers for Rhino '' ( Spider - Man 's Tangled Web ). An homage to Flowers for Algernon. ^ Despite first appearing in Spider - Man comic books, the Kingpin is more notable of being a Daredevil adversary. The character that represents the opposite of what Daredevil stands for. Despite this he is a major antagonist of both superheroes in the Marvel comic books just as recurringly. He also is a major recurring villain in the rest of the Marvel Universe crossing over as major antagonists to superheroes / antiheroes ( such as the Punisher ) in certain comic books of the many based universes of Marvel. ( PunisherMAX. etc. ) ^ `` The Six Arms Saga '' is the name of the storyline that debuted Morbius. ^ Miles Warren 's technical first appearance was revealed to be in The Amazing Spider - Man # 31 ( December 1965 ) created by Stan Lee and Steve Ditko before being revealed as the Jackal. ^ Although she is listed with the supervillains as she sometimes is depicted in certain portrayals. The Black Cat is more regarded as a anti-heroine than fully supervillain. A character that struggles in between deciding good and bad... and the major femme fatale romantic interest for Spider - Man. Her key role of deciding between crime and having complicated relationships of Spider - Man makes her sometimes labeled as part with the rest of the major rogues gallery of Spider - Man. Nonetheless she has been a staple supporting Spider - Man character during her debut. ^ The Amazing Spider - Man # 299 is the first appearance of Eddie Brock as Venom. The alien costume debuted from The Amazing Spider - Man # 252 and the symbiote bonded to Spider - Man in Secret Wars # 8. Venom 's creators are determined by pre-alien costume by not counting the creators / designers of the alien costume, David Michelinie or Mike Zeck, or the Marvel Comics fan who originally though of the concept for the creators. ^ Cletus Kasady first appeared in The Amazing Spider - Man 344. Carnage is a major character in the popular storyline `` Maximum Carnage ''. ^ Despite standing out as his own independent character now. The Punisher was originally introduced as an antagonist of Spider - Man. See also Savage Six : Antagonists of Spider - Girl and Flash Thompson 's Venom similar to the Sinister Six. The Superior Foes of Spider - Man : A comic book series starring Spider - Man villains. Janice Lincoln : The third Beetle who would then be featured as one of the Sinister Six on The Superior Foes of Spider - Man. References ^ Jump up to : Yehl, Joshua ; Schedeen, Jesse. `` Top 25 Spider - Man Villains : Part 1 ''. IGN. Retrieved 12 December 2016. Jump up ^ `` Top 25 Spider - Man Villains : Page 3 of 5 ''. IGN. 16 April 2014. Retrieved 18 June 2015. ^ Jump up to : DeFalco, Tom ; Gilbert, Laura, ed. ( 2008 ). `` 1960s ''. Marvel Chronicle A Year by Year History. Dorling Kindersley. p. 87. ISBN 978 - 0756641238. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 36. ISBN 978 - 0756692360. Now it was time for ( John Romita, Sr. ) to introduce a new Spidey villain with the help of ( Stan ) Lee. Out of their pooled creative energies was born the Rhino, a monstrous behemoth trapped in a durable rhinoceros suit. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning `` 1970s '' in Gilbert ( 2012 ), p. 62 : `` ( The Amazing Spider - Man # 111 ) marked the dawning of a new era : writer Gerry Conway came on board as Stan Lee 's replacement. Alongside artist John Romita, Conway started his run by picking up where Lee left off. '' Jump up ^ Manning `` 1970s '' in Gilbert ( 2012 ), p. 68 : `` This story by writer Gerry Conway and penciler Gil Kane would go down in history as one of the most memorable events of Spider - Man 's life. '' Jump up ^ David and Greenberger p. 49 : `` The idea of beloved supporting characters meeting their deaths may be standard operating procedure now but in 1973 it was unprecedented... Gwen 's death took villainy and victimhood to an entirely new level. '' ^ Jump up to : `` Venom is the 33rd greatest comic book character. ''. Empire.com. Retrieved 25 April 2015. ^ Jump up to : Siegel, Lucas. `` The 10 Greatest SPIDER - MAN Villains of ALL TIME ! ''. Newsarama. Retrieved 2 January 2014. ^ Jump up to : Beard, Jim. `` ARCHRIVALS : SPIDER - MAN VS THE VULTURE ''. Marvel.com. Retrieved 2 January 2014. Jump up ^ Kyle, Scmidlin. `` 10 Spider - Man Villains ( And Combinations ) Deserving Of The Big Screen ( 7. The Vulture ) ''. What Culture !. Retrieved 2 January 2014. `` He 's been one of Spider - Man 's most frequent and iconic antagonists ever since his first appearance in issue 2 of The Amazing Spider - Man. Jump up ^ DeFalco `` 1960s '' in Gilbert ( 2008 ), p. 92 : `` Introduced in the lead story of The Amazing Spider - Man # 2 and created by Stan Lee and Steve Ditko, the Vulture was the first in a long line of animal - inspired super-villains that were destined to battle everyone 's favorite web - slinger. '' Jump up ^ Dowell, Gary ; Holman, Greg ; Halperin, James L. HCA Heritage Comics Auction Catalog. Heritage Capital Corporation. ^ Jump up to : Stan Lee ( w ), Steve Ditko ( p ), Steve Ditko ( i ). The Uncanny Threat of the Terrible Tinkerer ! 5 ( September 1997 ), Marvel Comics ^ Jump up to : DeFalco `` 1960s '' in Gilbert ( 2008 ), p. 93 : `` Dr. Octopus shared many traits with Peter Parker. They were both shy, both interested in science, and both had trouble relating to women... Otto Octavius even looked like a grown up Peter Parker. Lee and Ditko intended Otto to be the man Peter might have become if he had n't been raised with a sense of responsibility. ^ Jump up to : Lee, Stan ( w ), Ditko, Steve ( p ), Ditko, Steve ( i ). `` Spider - Man Versus Doctor Octopus '' The Amazing Spider - Man 3 ( July 1963 ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 20. ISBN 978 - 0756692360. In this installment, Stan Lee and Steve Ditko introduced Sandman - a super villain who could turn his entire body into sand with a single thought. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Lee, Stan ( w ), Ditko, Steve ( p ), Ditko, Steve ( i ). `` Nothing Can Stop... The Sandman ! '' The Amazing Spider - Man 4 ( September 1963 ) ^ Jump up to : DeFalco `` 1960s '' in Gilbert ( 2008 ), p. 95 ^ Jump up to : Lee, Stan ( w ), Ditko, Steve ( p ), Ditko, Steve ( i ). `` Face - to - Face With... the Lizard ! '' The Amazing Spider - Man 6 ( November 1963 ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 20. ISBN 978 - 0756692360. The Amazing Spider - Mans sixth issue introduced the Lizard. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 24. ISBN 978 - 0756692360. The Brain is an early Mobile Computer prototype built by I.C.M. in Midtown High School, where Peter Parker attended, it was deemed obsolete after Spidey 's first encounter with it but it came back again. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Stan Lee ( w ), Steve Ditko ( p ), Steve Ditko ( i ). `` The Terrible Threat Of The Living Brain ! '' The Amazing Spider - Man 8 ( January, 1964 ), Marvel Comics Jump up ^ DeFalco `` 1960s '' in Gilbert ( 2008 ), p. 98 Jump up ^ Lee, Stan ( w ), Ditko, Steve ( p ), Ditko, Steve ( i ). `` The Man Called Electro ! '' The Amazing Spider - Man 9 ( February 1964 ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 24. ISBN 978 - 0756692360. Electro charged into Spider - Man 's life for the first time in another ( Stan ) Lee and ( Steve ) Ditko effort that saw Peter Parker using his brilliant mind to outwit a foe. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Gross, Edward ( 2002 ). Spider - Man Confidential : From Comic Icon to Hollywood Hero. ISBN 0786887222. ^ Jump up to : Lee, Stan ( w ), Ditko, Steve ( p ), Ditko, Steve ( i ). `` The Menace of... Mysterio ! '' The Amazing Spider - Man 13 ( June 1964 ) ^ Jump up to : `` Mysterio is number 85 on greatest comic book villain of all time. ''. IGN. Archived from the original on 3 November 2013. Retrieved 3 January 2014. ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 25. ISBN 978 - 0756692360. The Amazing Spider - Man # 13 saw ( Stan ) Lee and ( Steve ) Ditko return to the creation of new super villains. This issue marked the debut of Mysterio, a former special effects expert named Quentin Beck. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Albert, Aaron. `` Green Goblin Profile ''. About.com. Retrieved 3 January 2014. Jump up ^ Beard, Jim. `` SPIDER - MAN 3 : THE SPIDER & THE GOBLIN ''. Marvel.com. Retrieved 3 January 2014. ^ Jump up to : Yehl, Josh, Schedeen, Jesse. `` Top 25 Spider - Man villains : Part 4 ''. IGN. Retrieved 19 April 2014. CS1 maint : Multiple names : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 26. ISBN 978 - 0756692360. Spider - Man 's arch nemesis, the Green Goblin, as introduced to readers as the ' most dangerous foe Spidey 's ever fought. ' Writer Stan Lee and artist Steve Ditko had no way of knowing how true that statement would prove to be in the coming years. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 26. ISBN 978 - 0756692360. ( Stan ) Lee and ( Steve ) Ditko 's newest villain, Kraven the Hunter, debuted in this issue. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 28. ISBN 978 - 0756692360. Spider - Man felt the Scorpion 's sting for the first time in another Stan Lee and Steve Ditko collaboration. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 29. ISBN 978 - 0756692360. While he would n't have the same staying power as many other Stan Lee / Steve Ditko creations, the Crime Master gave villainy a good shot in this first half of a two - part Spider - Man adventure. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 30. ISBN 978 - 0756692360. Mark Raxton was a corrupt partner of ( Spencer ) Smythe 's who worked with him on a liquid metal alloy project. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Dowell, Gary ; Holman, Greg ; Halperin, James L. HCA Heritage Comics Auction Catalog. Heritage Capital Corporation. ^ Jump up to : `` The 10 WORST Spider - Man Villains of All Time ! ''. Newsarama. Retrieved 5 June 2015. Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 34. ISBN 978 - 0756692360. Spider - Man was introduced to a new character in the form of the super villain called the Looter. The product of another ( Stan ) Lee and ( Steve ) Ditko collaboration, the Looter was born when hiker Norton G. Fester discovered and experimented on a mysterious meteor. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Gina Renée, Misiroglu, ; Eury, Michael. The Supervillain Book : The Evil Side of Comics and Hollywood. Visible Ink Press. ISBN 0780809777. CS1 maint : Multiple names : authors list ( link ) Jump up ^ Lee, Stan ( w ), Romita, Sr., John ( p ), Esposito, Mike ( i ). `` The Horns of the Rhino ! '' The Amazing Spider - Man 41 ( October 1966 ) Jump up ^ Lealos, Shawn S. ( 9 October 2010 ). `` Alternate Takes 10.02. 10 - Greatest Spider - Man Adversaries, Part 1 ''. 411.Mania.com. Retrieved 4 January 2014. Jump up ^ Lee, Stan ( w ), Romita, Sr., John ( p ), Romita, Sr., John ( i ). `` The Sinister Shocker ! '' The Amazing Spider - Man 46 ( March 1967 ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 38. ISBN 978 - 0756692360. ( Stan ) Lee and ( John ) Romita 's second major Spidey villain appeared in the form of the Shocker, a criminal equipped with vibration - projecting gauntlets. CS1 maint : Extra text : authors list ( link ) Jump up ^ DeFalco `` 1960s '' in Gilbert ( 2008 ), p. 122 : `` Stan Lee wanted to create a new kind of crime boss. Someone who treated crime as if it were a business... He pitched this idea to artist John Romita and it was Wilson Fisk who emerged in The Amazing Spider - Man # 50. '' Jump up ^ Lee, Stan ( w ), Romita, Sr., John ( p ), Esposito, Mike ( i ). `` Spider - Man No More ! '' The Amazing Spider - Man 50 ( July 1967 ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 40. ISBN 978 - 0756692360. Although he made his debut in the previous issue, it was in this ( Stan ) Lee and ( John ) Romita tale ( The Amazing Spider - Man # 51 ) that the Kingpin - real name Wilson Fisk - really left his mark on organized crime. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Stan Lee ( w ), Larry Lieber ( p ), Mickey Esposito ( i ). The Amazing Spider - Man Annual 5 ( September 1997 ), Marvel Comics Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 48. ISBN 978 - 0756692360. Spider - Man called the Shocker 's ex-girlfriend, only to find her home under siege by a giant thug named Man Mountain Marko. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 48. ISBN 978 - 0756692360. ( Man Mountain Marko ) was n't the biggest threat the web - slinger would face in this issue. That honor went to Silvermane, an elderly crime boss intent on regaining his youth. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Rovin, Jeff ( 1987 ). The encyclopedia of super villains. ISBN 081601356X. ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 52. ISBN 978 - 0756692360. A new villain jumped into Spider - Man 's life when the Kangaroo debuted, thanks to writer Stan Lee and artists John Buscema, Jim Mooney, and John Romita. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Boland, Robbie. `` 10 Spectacularly Third - Rate Spider - Man Villains ( Part two ) ''. Topless Robot. Retrieved 5 June 2015. ^ Jump up to : Yell, April, Schedeen, Jesse. `` Top 25 Spider - Man villains : Part 2 ''. IGN. Retrieved 19 April 2014. CS1 maint : Multiple names : authors list ( link ) ^ Jump up to : `` 50 Greatest Friends and Foes of Spider - Man : Villains # 25 - 16 ''. Comic Book Resources. Retrieved 27 April 2015. ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 59. ISBN 978 - 0756692360. In the first issue of The Amazing Spider - Man to be written by someone other than Stan Lee... Thomas also managed to introduce a major new player to Spidey 's life - the scientifically created vampire known as Morbius. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 61. ISBN 978 - 0756692360. Stan ( Lee ) could n't leave ( the series ) without gifting the readers one last new villain. With John Romita fulfilling the art chores, he crafted the Gibbon, an orphan named Martin Blank who was cursed from birth with a primitive, ape - like appearance. CS1 maint : Extra text : authors list ( link ) Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 63. ISBN 978 - 0756692360. Writer Gerry Conway made his first major contribution to the Spider - Man saga... a new mobster was on the rise in New York 's underworld - Hammerhead. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Boland, Robbie. `` 10 Spectacularly Third - Rate Spider - Man Villains ( Part one ) ''. Topless Robot. Jump up ^ Dan Slott ( w ), Marcos Martin ( p ), Marcos Martin ( i ). `` Mysterioso, Part 1 : Un-Murder Incorporated '' The Amazing Spider - Man # 618 ( March 2010 ), United States : Marvel Comics Jump up ^ `` AMAZING SPIDER - MAN ( 1963 ) # 113 ''. Marvel. Retrieved 27 April 2015. ^ Jump up to : Williams, Scott E. ( October 2010 ). `` Gerry Conway : Everything but the Gwen Stacy Sink ''. Back Issue !. TwoMorrows Publishing ( 44 ) : 7. Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 73. ISBN 978 - 0756692360. The Man - Wolf, a major new threat to Spider - Man and his supporting cast, was introduced in a two - part tale that saw the werewolf terrorize J. Jonah Jameson. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 72. ISBN 978 - 0756692360. Writer Gerry Conway and artist Ross Andru introduced two major new characters to Spider - Man 's world and the Marvel Universe in this self - contained issue. Not only would the vigilante known as the Punisher go on to be one of the most important and iconic Marvel creations of the 1970s, but his instigator, the Jackal, would become the next big threat in Spider - Man 's life. CS1 maint : Extra text : authors list ( link ) ^ Jump up to : Couper - Smartt, Jonathan ( 2006 ). Marvel encyclopedia : Spider - Man. Marvel Publishing Inc. ISBN 9780785124283. Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1970s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 77. ISBN 978 - 0756692360. With every bit of order in Spider - Man 's life came a fair amount of disorder, and in this ( Gerry ) Conway / ( Ross ) Andru issue, that chaos came in the form of another new Spider - Man villain, the Grizzly. CS1 maint : Extra text : authors list ( link ) Jump up ^ HCA Comics and Comic Art Auction Catalog # 7021, Dallas, TX. Heritage Capital Corporation. ISBN 1599674580. Jump up ^ `` Human Fly ''. Comic Book Resources. Retrieved 5 June 2015. ^ Jump up to : Manning `` 1970s '' in Gilbert ( 2012 ), p. 107 : `` Spider - Man was n't exactly sure what to think about his luck when he met a beautiful new thief on the prowl named the Black Cat, courtesy of a story by writer Marv Wolfman and artist Keith Pollard. '' ^ Jump up to : 813 Heritage Comic Auctions, Comic and Comic Art Auction Catalog. Heritage Capital Corporation. ISBN 193289926X. Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1980s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 118. ISBN 978 - 0756692360. In this issue, award - winning writer Denny O'Neil, with collaborator John Romita, Jr., introduced Hydro - Man. CS1 maint : Extra text : authors list ( link ) Jump up ^ `` AMAZING SPIDER - MAN ( 1963 ) # 212 ''. Marvel. Retrieved 27 April 2015. Jump up ^ Terry Kavanagh ( w ), Steven Butler ( p ), Randy Emerlin ( i ). `` Lives Unlived '' Web of Spider - Man # 125 ( June, 1995 ), United States : Marvel Comics Jump up ^ David and Greenberger, pp. 68 - 69 : `` Writer Roger Stern is primarily remembered for two major contributions to the world of Peter Parker. One was a short piece entitled ' The Kid Who Collects Spider - Man '... ( his ) other major contribution was the introduction of the Hobgoblin. '' ^ Jump up to : Manning `` 1980s '' in Gilbert ( 2012 ), p. 133 : `` Writer Roger Stern and artists John Romita, Jr. and John Romita, Sr. introduced a new - and frighteningly sane - version of the ( Green Goblin ) concept with the debut of the Hobgoblin. '' Jump up ^ Greenberg, Glenn ( August 2009 ). `` When Hobby Met Spidey ''. Back Issue ! ( 35 ). TwoMorrows Publishing. pp. 10 -- 23. Jump up ^ Greenberg, Glenn ( August 2009 ). `` When Hobby Met Spidey ''. Back Issue !. TwoMorrows Publishing ( 35 ) : 15. Jump up ^ DeFalco `` 1980s '' in Gilbert ( 2008 ), p. 218 : `` Created by writer Tom DeFalco and artist Rick Leonardi, the villain tended his rose garden as he casually ran his various criminal enterprises. '' Jump up ^ `` Top 25 Spider - Man villains : Part 4 ''. IGN. Retrieved 1 November 2014. Jump up ^ `` AMAZING SPIDER - MAN ANNUAL ( 1964 ) # 19 ''. Marvel. Retrieved 26 April 2015. Jump up ^ `` Marc Webb reveals B.J. Novak 's Amazing Spider - Man 2 role ''. Comic Book Resources. Retrieved 27 April 2015. Jump up ^ Ryall, Chris ; Tipton, Scott ( 2009 ). Comic books 101 the history, methods and madness. Cincinnati, Ohio : IMPACT. ISBN 9781440307904. I think Slyde 's first appearance ( The Amazing Spider - Man # 272, January 1986 ) is pretty goofy ( non-stick coating on a super-villain suit ? Sure ! ) Jump up ^ Manning `` 1980s '' in Gilbert ( 2012 ), p. 169 : `` In this landmark installment ( issue # 298 ), one of the most popular characters in the wall - crawler 's history would begin to step into the spotlight courtesy of one of the most popular artists to ever draw the web - slinger. '' ^ Jump up to : `` Venom is number 22 on greatest comic book villain of all time ''. IGN. Retrieved 25 April 2015. Jump up ^ Claremont, Chris ; David,, Peter ( 2014 ). Wolverine Epic Collection : Madripoor Nights. ISBN 0785189033. Issue # 309 will culimate the Mary Jane storyline. I am introducing a new duo of bad guys called Styx and Stones. Styx is a mastermind who loves death, adores death, and he 's got these plans to bring death in all of its wonderful forms. Stones is his partner who actually carries out these things. Jump up ^ `` Carnage is number 90 on greatest comic book villain of all time ''. IGN. Retrieved 25 April 2015. ^ Jump up to : Cowsill, Alan ; Gilbert, Laura, ed. ( 2012 ). `` 1990s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 197. ISBN 978 - 0756692360. Artist Mark Bagley 's era of The Amazing Spider - Man hit its stride as Carnage revealed the true face of his evil. Carnage was a symbiotic offspring produced when Venom bonded to psychopath Cletus Kasady. '' CS1 maint : Extra text : authors list ( link ) Jump up ^ Michelinie, David ( w ), Bagley, Mark ( p ), Emberlin, Randy ( i ). `` Carnage : Part One '' The Amazing Spider - Man 361 ( April 1992 ) Jump up ^ Papageorgiou, Solon. `` 10 facts about Batman, Spider - Man, Iron Man you did n't know. ''. Moviepilot. Retrieved 25 April 2015. Jump up ^ Fuller, Kevin ( 13 February 2008 ). `` Amazing Spider - Man # 550 Review ''. IGN. Retrieved 16 June 2015. Jump up ^ `` Forget it, Spidey ! It 's Chinatown : Van Lente On Mister Negative ''. Comic Book Resources. Retrieved 27 April 2015. Jump up ^ Seigel, Lucas ( 2 October 2013 ). `` All - New Marvel NOW ! Teaser Trifecta : ' OVERDRIVE, ' WRATH ', ' HUNTED ' ''. Newsarama. Retrieved 16 June 2015. Jump up ^ `` Preview : Amazing Spider - Man # 656 ''. comicbookresources.com. Jump up ^ `` Superior Spider - Man # 4 : Massacre 's Back ''. Crave Online. Jump up ^ `` Amazing Spider - Man ( 1999 ) # 655 ''. Marvel.com. Jump up ^ `` The Amazing Spider - Man # 655 Review ''. ign.com. Jump up ^ `` Amazing Spider - Man # 655 ''. comicbookresources.com. Jump up ^ Franich, Darren. `` ' Amazing Spider - Man ' : Our villain wish list for the Sinister Six ''. Entertainment Weekly. Retrieved 5 June 2015. Jump up ^ Milgron, Al ( w ), Trimpe, Herb ( p ). `` True Confessions '' The Spectacular Spider - Man # 98 ( January, 1985 ), United States : Marvel Comics Jump up ^ Peter David ( w ), Steve Ditko ( p ), Mark Beachum ( i ). `` Things Fall Apart '' Peter Parker, The Spectacular Spider - Man 15 ( June, 1986 ), Marvel Comics ^ Jump up to : J.M. DeMatteis ( w ), Kerry Gammill ( p ), Mike Esposito ( i ). `` The Best Things In Life Are Free... But Everything Else Costs Money ! '' Marvel Team - Up 131 ( July, 1983 ), Marvel Comics Jump up ^ Kraft, David ( August 2009 ). `` When Hobby Met Spidey ''. Back Issue !. TwoMorrows Publishing ( 51 ) : 1. Jump up ^ DeFalco `` 1980s '' in Gilbert ( 2008 ), p. 218 : `` Created by writer David Kraft and artist Keith Giffen. '' ^ Jump up to : Lee, Stan ( w ), Ditko, Steve ( a ). Amazing Fantasy 15 ( Aug 1962 ), New York City, New York : Marvel Comics Jump up ^ Orange, Alan ( November 17, 2015 ). `` Chris Zylka Is Eugene Flash Thompson in Spider - Man ''. MovieWeb. Retrieved November 27, 2010. Jump up ^ Brian Cronin ( May 13, 2011 ). Comic Book Resources, ed. `` Comic Book Legends Revealed # 313 ''. Retrieved June 19, 2015. Jump up ^ David Michelinie ( w ), Mike Harris ( p ), Kyle Baker ( i ). `` Fox Hunter '' Web of Spider - Man 15 ( June 1986 ), Marvel Comics Jump up ^ Howard Mackie ( w ), Tom Lyle ( p ). `` Cold Hearts '' Spider - Man 49 ( August 1994 ), Marvel Comics Jump up ^ Tom DeFalco ( w ), Mark Bagley ( p ), Larry Mahlstedt ( i ). `` Deadly is Delilah '' The Amazing Spider - Man 414 ( August 1996 ), Marvel Comics Jump up ^ Tom DeFalco ( w ), Steve Skroce ( p ), Bud LaRosa ( i ). `` Twas The Night Before Christmas... '' The Amazing Spider - Man 420 ( February 1997 ), Marvel Comics Jump up ^ Loners # 5 Comic -- September 12, 2007 Jump up ^ Tom DeFalco ( w ), Joe Bennett ( p ), Bud LaRosa ( i ). `` Exposed Wiring '' The Amazing Spider - Man 422 ( April 1997 ), Marvel Comics Jump up ^ Tom DeFalco ( w ), Joe Bennett ( p ), Bud LaRosa ( i ). `` Exposed Wiring '' The Amazing Spider - Man 422 ( April 1997 ), Marvel Comics Jump up ^ Tom DeFalco ( w ), Steve Skroce ( p ), Bud LaRosa ( i ). `` Sacrifice Play ! '' The Amazing Spider - Man 427 ( September 1997 ), Marvel Comics Jump up ^ Tom Lyle ( w ). `` Maximum Clonage - ( Conclusion ! ) The End of the Beginning ! '' Spider - Man : Maximum Clonage : Omega ( August, 1995 ), Marvel Comics Jump up ^ Manning, Matthew K. ; Gilbert, Laura, ed. ( 2012 ). `` 1960s ''. Spider - Man Chronicle Celebrating 50 Years of Web - Slinging. Dorling Kindersley. p. 24. ISBN 978 - 0756692360. While never reaching the popularity of previous ( Stan ) Lee and ( Steve ) Ditko collaborations, the Enforcers managed to give the wall - crawler a run for his money in their first appearance. CS1 maint : Extra text : authors list ( link ) Jump up ^ http://insidepulse.com/2015/02/23/the-entire-spider-verse-review-spoilers-from-marvel-comics-amazing-spider-man-to-scarlet-spiders-to-spider-woman-to-2099-all-of-it-a-tidy-epilogue/ Jump up ^ Valentine, Eve. `` Who Are the Sinister Six ? -- An Introduction to Spider - Man 's Supervillain Group ''. Collider. Retrieved 14 June 2015. Jump up ^ Glenn Greenberg ( w ), Luke Ross ( p ), Al Milgrom ( i ). `` The Legion of Losers ! '' The Spectacular Spider - Man 246 ( May, 1997 ), Marvel Comics Jump up ^ Tom DeFalco ( w ), Ron Frenz Brett Breeding ( p ), Brett Breeding ( i ). `` The Sinister Syndicate ! '' The Amazing Spider - Man 280 ( September, 1986 ), Marvel Comics ^ Jump up to : Albert, Aaron. `` Top ten comic book archenemies ''. About.com. Retrieved 3 January 2014. ^ Jump up to : `` Doctor Octopus is number 28 on greatest comic book villain of all time. ''. IGN. Retrieved 2 January 2014. ^ Jump up to : Hanks, Henry. `` Events in landmark ' Spider - Man ' issue have fans in a frenzy ''. CNN. Retrieved 2 January 2014. Jump up ^ Cronin, Brian. `` 50 Greatest Friends and Foes of Spider - Man : Villains # 1 - 3 ''. Comic Book Resources. Retrieved 2 January 2014. Jump up ^ `` The ULTIMATE SPIDER - MAN writer talks about Spidey 's new Amazing Friends and lays the Osborns to rest once and for all Marvel.com News ''. Marvel.com. Retrieved 2010 - 04 - 27. Jump up ^ `` Love is in the air as Marvel. com 's Secret Cabal picks the greatest Marvel romances of all in time for Valentine 's Day Marvel.com News ''. Marvel.com. Retrieved 2010 - 04 - 27. Jump up ^ Yehl, Joshua ; Schedeen, Jess. `` Top 25 Spider - Man Villain : Part 5 ''. IGN. Retrieved 19 April 2014. Jump up ^ `` Norman Osborn is number 13 on greatest comic book villain of all time. ''. IGN. Archived from the original on 21 October 2013. Retrieved 3 January 2014. Jump up ^ `` Spider - Man villains tournament : Championship ''. IGN. Retrieved 25 April 2015. Jump up ^ Shutt, Craig ( August 1997 ). `` Villain Turned Hero : Venom ''. Wizard ( 72 ). p. 37. Jump up ^ McMillan, Graeme ( 15 February 2015 ). `` ' Spider - Man ' : 10 Recommendations for a Successful Reboot ''. The Hollywood Reporter. Archived from the original on 4 May 2015. Retrieved 18 June 2015. ^ Jump up to : Moore, Ben ( 7 July 2013 ). `` Comic - Con 2013 : ' Amazing Spider - Man ' Sinister Six Hints Revealed ( Updated ) ''. Screenrant. Retrieved 18 June 2015. Jump up ^ Mendelson, Scott ( 3 March 2015 ). `` ' Spider - Man ' Gives Marvel What It Needs Most : Villains ''. Forbes.com. Forbes. Retrieved 18 June 2015. Jump up ^ `` 5 Huge Questions In The Wake Of Marvel 's Spider - Man Reveal : 2. Who Will Be The Main Villain ? ''. Cinema Blend. Retrieved 18 June 2015. ^ Jump up to : George, Marston ( 7 August 2013 ). `` The 10 Greatest ROGUES GALLERIES of ALL TIME ! ''. Newsarama. Retrieved 18 June 2015. Jump up ^ Kyle, Scmidlin. `` 10 Spider - Man Villains ( And Combinations ) Deserving Of The Big Screen ''. What Culture !. Retrieved June 8, 2015. Spider - Man 's rogues gallery is one of the most colorful in comics. Only Batman could boast a greater number of well - established crooks and costumed ne'er - do - wells, and even that 's debatable. Jump up ^ Perry, Spencer. `` Spidey Turns 50 : 11 Villains Who Could Be in The Amazing Spider - Man 2 ''. Superherohype.com ( CraveOnline ). Retrieved 2 January 2014. Jump up ^ Cronin, Brian. `` 50 Greatest Friends and Foes of Spider - Man : Villains # 6 - 4 ''. Comic Book Resources. Retrieved 2 January 2014. ^ Jump up to : Schmidlin, Kyle. `` 10 Spider - Man Villains ( And Combinations ) Deserving Of The Big Screen ( 3. Chameleon and the Kraven the Hunter ) ''. What Culture !. Retrieved 2 January 2014. Jump up ^ Lee, Stan ( w ), Kirby, Jack ( p ), Stone, Chic ( i ). `` The Attack of the evil Frightful Four '' Fantastic Four # 36 ( March 1965 ) Jump up ^ Marc Steven Sumerak ( w ), Eric Eng Wong ( p ), John G. Roshell ( i ). `` An A-Z Compedium of Earth 's Mighiest Heroes '' Avengers Casebook 1999 1 ( February 2000 ), Marvel Comics Jump up ^ Cronin, Brian. `` 50 Greatest Friends and Foes of Spider - Man : Villains # 10 - 7 ''. Comic Book Resources. Retrieved 3 January 2014. Jump up ^ `` Electro is number 87 on greatest comic book villain of all time. ''. IGN. Retrieved 3 January 2014. Jump up ^ Lee, Stan ( w ), Orlando, Joe ( p ), Coletta, Vince ( i ). `` The Evil Menace of Electro '' Daredevil # 2 ( September 1964 ) Jump up ^ Booke, M. Keith ( ed. ). `` Daredevil ''. Encyclopedia of Comic Books and Graphic Novels : Two Volumes. p. 134. Jump up ^ Lee, Stan ( w ), Colan, Gene ( p ), Tartaglione, John ( i ). `` Electro and his Emissaries of Evil '' Daredevil Annual # 1 ( September 1967 ) Jump up ^ `` Kraven the Hunter is number 53 on greatest comic book villain of all time. ''. IGN. Retrieved 4 January 2014. Jump up ^ Zalben, Alex. `` The 10 greatest Spider - Man villains ever. ''. MTV. Retrieved 4 January 2014. Jump up ^ Bendis, Brian Michael ( w ), Bagley, Mark ( p ), Isanove, Ricard ( col ), Petit, Cory ( let ). Ultimate Spider - Man # 97 ( September 2006 ) Jump up ^ Reed, Brian ( w ), Craig, Wesley ( p ), Craig, Wesley ( i ), Fairbairn, Nathan ( col ), Petit, Cory ( let ). Timestorm 2009 -- 2099 # 1 ( August 2009 ) Jump up ^ `` Journey of the Iron Fist ''. Ultimate Spider - Man. Season 2. Episode 39. June 16, 2013. Disney XD. Jump up ^ Lealos, Shawn. `` Alternate Takes 10.02. 10 - Greatest Spider - Man Adversaries, Part 1 ''. 411mania.com. Retrieved 4 January 2014. Jump up ^ Serafino, Jason. `` The top 25 Spider - Man Stories Of All Time : 16. Flowers For the Rhino ''. Complex.com. Retrieved 4 January 2014. Jump up ^ `` Kingpin is number 10 on greatest comic book villain of all time ''. IGN. Retrieved 19 April 2014. Jump up ^ Sims, Chris. `` Frank Castle Goes To Jail in ' Punisher Max ' # 12 ( Exclusive Preview ) ''. ComicsAlliance. Archived from the original on 20 April 2014. Retrieved 19 April 2014. Jump up ^ Manning `` 1960s '' in Gilbert ( 2012 ), p. 31 : `` This monumental issue saw the first appearances of Peter 's upcoming love interest Gwen Stacy, prospective best friend, Harry Osborn, and even the future super villain known as the Jackal. '' Jump up ^ Cronin, Brian ( May 16, 2007 ). `` Comic Book Urban Legends Revealed Extra : Randy Schueller 's Brush With Comic History & # 124 ''. Comic Book Resources. Jump up ^ Shooter, Jim ( w ), Zeck, Mike ( p ), Beatty, John ; Abel, Jack ; Esposito, Mike ( i ). `` Invasion ! '' Marvel Super Heroes Secret Wars 1 ( December 1984 ), Marvel Comics Jump up ^ `` 50 Greatest Spider - Man Stories : # 25 - 21 ''. Comic Book Resources. Retrieved 25 April 2015. Jump up ^ Tom DeFalco ( w ), Pat Olliffe ( p ), Al Williamson ( i ). `` The Sinister Syndicate ! '' Spider - Girl 25 ( October, 2000 ), Marvel Comics Jump up ^ `` Bunn Takes Over VENOM, Kills Marvel Universe with DEADPOOL ''. Newsarama. June 5, 2012. Retrieved June 16, 2015. ^ Jump up to : White, Brett ( 20 December 2013 ), Recruiting 6 Spider - Man Villains for Sony 's `` Sinister Six '', Comic Book Resources. External links Category : Spider - Man Villains at Marvel.com Spider - Man Villains at Marvel Database Top 10 Greatest Spider - Man Villains by WatchMojo.com 50 Greatest Spider - Man 's Villains by GamesRadar. April 14, 2014 Spider - Man Stan Lee Steve Ditko Spider - Man family By secret identity Spider - Man Scarlet Spider Spider - Woman Steel Spider Silk By public identity Peter Parker Ben Reilly Julia Carpenter Kaine Parker Mattie Franklin Anya Corazon Supporting characters Liz Allan Black Cat Betty Brant Billy Connors Martha Connors Carlie Cooper Jean DeWolff Glory Grant J. Jonah Jameson John Jameson Ashley Kafka Ned Leeds Madame Web Anna Maria Marconi Max Modell Harry Osborn Ben Parker May Parker Richard and Mary Parker Prowler Puma Randy Robertson Robbie Robertson Rocket Racer Silver Sable Sophia `` Chat '' Sanduval George Stacy Gwen Stacy Flash Thompson Ben Urich Mary Jane Watson Debra Whitman Will o ' the Wisp Antagonists Central rogues gallery Carnage Chameleon Doctor Octopus Electro Green Goblin Norman Osborn Hobgoblin Roderick Kingsley Jason Macendale Phil Urich Hydro - Man Jackal Kingpin Kraven the Hunter Lizard Morbius, the Living Vampire Mysterio Rhino Sandman Scorpion Shocker Sinister Six Venom Eddie Brock Vulture Recurring antagonists Beetle Abner Jenkins Janice Lincoln Big Wheel Boomerang Burglar Calypso Cyclone Demogoblin Enforcers Fancy Dan Montana Ox Grizzly Hammerhead Human Fly Jack O ' Lantern Jason Macendale Kangaroo Lady Octopus Living Brain Man - Wolf Menace Mendel Stromm Mister Negative Molten Man Morlun Moses Magnum Ringer Speed Demon Alistair Smythe Spencer Smythe Spider - Slayer list Silvermane Spot Stegron Swarm Tinkerer Tombstone Walrus Alternative versions Spider - Man Spider - Man 2099 Spider - Girl Spider - Gwen Spider - Ham Spider - Man Noir Ultimate Spider - Man Miles Morales Alternative versions of Mary Jane Watson Alternative versions of the Green Goblin Alternative versions of Venom Locations Midtown High School Daily Bugle Empire State University Oscorp Parker Industries Alchemax Comic books The Amazing Spider - Man issues Storylines In other media In film In television In video games In literature ‎ novels book series Toys Spider - Man ( 2010 toy line ) Spider - Man Classics Spider - Man and Friends Lego Spider - Man Spider - Man ( pinball ) The Amazing Spider - Man ( pinball ) Related topics Powers and equipment Goblin Slingers Symbiotes Sinister Six Stan Lee Steve Ditko Members Original Doctor Octopus Electro Kraven the Hunter Mysterio Sandman Vulture Recurring Beetle Abner Jenkins Janice Lincoln Boomerang Chameleon Gog Green Goblin Norman Osborn Grim Reaper Hammerhead Hobgoblin Jason Macendale Hydro - Man Lizard Overdrive Rhino Scorpion Mac Gargan Shocker Speed Demon Swarm Tombstone Trapster Venom In other media Spider - Man : Return of the Sinister Six Spider - Man 2 : The Sinister Six Other Spider - Man All Spider - Man enemies In other media Savage Six Sinister Syndicate The Superior Foes of Spider - Man Ultimate Six Retrieved from `` https://en.wikipedia.org/w/index.php?title=List_of_Spider-Man_enemies&oldid=802610496 '' Categories : Lists of Spider - Man characters Lists of supervillains Hidden categories : CS1 maint : Extra text : authors list CS1 maint : Multiple names : authors list Talk Contents About Wikipedia Français ქართული Nederlands Português Suomi Edit links This page was last edited on 27 September 2017, at 08 : 34. 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Question: who was the first villain spiderman ever fought
Answer: Chameleon