Grey 's Anatomy ( season 2 ) - wikipedia Grey 's Anatomy ( season 2 ) Grey 's Anatomy ( season 2 ) DVD cover art for the second season of Grey 's Anatomy Starring Ellen Pompeo Sandra Oh Katherine Heigl Justin Chambers T.R. Knight Chandra Wilson James Pickens, Jr. Kate Walsh Isaiah Washington Patrick Dempsey Country of origin United States No. of episodes 27 Release Original network ABC Original release September 25, 2005 ( 2005 - 09 - 25 ) -- May 15, 2006 ( 2006 - 05 - 15 ) Season chronology ← Previous Season 1 Next → Season 3 List of Grey 's Anatomy episodes The second season of the American television medical drama Grey 's Anatomy commenced airing on the American Broadcasting Company ( ABC ) on September 25, 2005, and concluded on May 15, 2006. The season was produced by Touchstone Television, in association with Shondaland production company and The Mark Gordon Company, the showrunner being Shonda Rhimes. Actors Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, and T.R. Knight reprised their roles as surgical interns Meredith Grey, Cristina Yang, Izzie Stevens, Alex Karev, and George O'Malley, respectively. Previous main cast members Chandra Wilson, James Pickens, Jr., Isaiah Washington, and Patrick Dempsey also returned, while Kate Walsh, who began the season in a recurring capacity, was promoted to series regular status, after appearing in seven episodes as a guest star. The season continued to focus on the surgical residency of five young interns as they try to balance the challenges of their competitive careers with the difficulties that determine their personal lives. It was set in the fictional Seattle Grace Hospital, located in the city of Seattle, Washington. Whereas the first season put the emphasis mainly on the unexpected impact the surgical field has on the main characters, the second season provides a detailed perspective on the personal background of each character, focusing on the consequences that their decisions have on their careers. Throughout the season, new story lines were introduced, including the love triangle between Meredith Grey, Derek Shepherd, and Addison Montgomery, the main arc of the season. Also heavily developed was the story line involving Izzie Stevens ' relationship with patient Denny Duquette, which resulted in critical acclaim and positive fan response. The season kept its original airtime from the previous season, taking over Boston Legal 's time slot at 10 : 00 pm on Sundays, while airing as a lead - out to the already successful ABC series, Desperate Housewives. It contained 27 episodes, out of which five were originally produced for the first season. In addition to the regular episodes, two clip shows recapped previous events of the show, both narrated by Steven W. Bailey in his recently introduced role as Joe the Bartender. `` Straight to Heart '' aired one week before the winter - holiday hiatus ended, recapping the most memorable events of the first season and the first half of the second. `` Under Pressure '' aired before the twenty - third episode. The season finale was conceived as a three - part story arc, the first of this kind in the series, and was scheduled to air on two consecutive nights. The show ended its second season with 21.07 million total viewers and a 6.9 ratings share in the 18 -- 49 demographic. The season opened to critical acclaim, as most agreed on a significant improvement in story lines. The season saw numerous cast and crew members receive awards and nominations at ceremonies like the 58th Primetime Emmy Awards and the 64th Golden Globe Awards. Katherine Heigl and Chandra Wilson were the cast members with the most nominations for their portrayals of Izzie Stevens and Miranda Bailey, respectively. The series was chosen in the top ten for several 2006 `` best of television '' lists, including USA Today, San Jose Mercury News, TV Guide, and Orlando Sentinel. Contents 1 Production 1.1 Crew 1.2 Writing and filming 2 Cast 2.1 Main Cast 3 Reception 3.1 Critical response 3.2 Awards and nominations 3.3 Ratings 4 Episodes 5 DVD release 6 References Production Crew The season was produced by Touchstone Television, currently ABC Studios, in association with ShondaLand Production Company and The Mark Gordon Company. Shonda Rhimes returned as the series ' showrunner and executive producer. She also continued her position from the first two seasons as one of the most prominent members of the writing staff. Betsy Beers, Mark Gordon, Mark Wilding, and Rob Corn returned as executive producers, along with James D. Parriott, Peter Horton, and Krista Vernoff, who have been in this position since the inception of the series. Parriott, who also served as an episodic writer, left the series at the conclusion of the season. Joan Rater and Tony Phelan continued to serve as co-executive producers, with Rater being a supervising producer as well. Stacy McKee, who would be promoted to co-executive producer for the third season, returned to the series as a producer and a member of the writing staff. Having written three episodes for the first season, Rhimes returned as a writer for five episodes. Parriott, Vernoff, Phelan, Rater, Wilding and Mimi Schmir were the most prominent members of the writing staff, with Parriott, Phelan, Rater, Wilding, Clack writing two episodes and Schmir producing the script for three. Gabrielle Stanton and Harry Werksman, Jr. worked together for the writing of two episodes, after having written one episode for the series in the past. Peter Horton served as both one of the executive producers and also directed five episodes. The season includes the first episode to be written Zoanne Clack, who would become one the series ' main writers, as well as a co-producer and executive story editor. Other writers include Kip Koenig, Blythe Robe and Elizabeth Klaviter. Executive producer Peter Horton returned to the series to direct five episodes for the season, after writing two episodes in the second season. Rob Corn directed two episodes, whereas Adam Davidson is credited for writing three episodes, his last ones in the series. Among the other directors are Wendey Stanzler, Mark Tinker, Jeff Melman, Jessica Yu, Lesli Linka Glatter, Michael Dinner, Dan Minahan, David Paymer, Julie Anne Robinson, Tricia Brock, and Seith Mann. Danny Lux continued his position as the main music composer for the series, while Herbert Davis, Tim Suhrstedt and Adam Kane served as the season 's cinematography directors. Susan Vaill and Edward Ornelas resumed their positions as editors, joined by Briana London, who left the series after nine episodes. Linda Lowy and John Brace, responsible for the casting since the beginning of the series, returned as casting team members. After the departure of Laurence Bennett, the production design team was taken over by Donald Lee Harris, with Amy B. Ancona and Brandee Dell'Aringa joining for ten episodes each. The series set decoration crew was led by Karen Bruck, whereas the costume design department was led by Linda M. Bass, who would leave the show at the conclusion of the season, following her being replaced by Mimi Melgaard. The make - up department was led by head Norman T. Leavitt, along with assistant make - up artist Brigitte Bugayong. The special make - up effects team consisted of Thomas R. Burman, Bari Dreiband - Burman and Bart Mixon. Arleen Chavez was the key hair stylist for the second season. Other make - up artists that contributed in the third season were Vincent Van Dyke, Allan Holt and Christopher Payne. The series production managers were unit production managar Carla Corwin and post-production supervisor Joy Ramos, who both depart from the series at the conclusion of the season, being replaced by unit production managar Jeff Rafner, production manager Chad Alber and production executive Tim Herbstrith. Second assistant directors since the inception of the series, Laura Petticord, Shawn Hanley and Chris Hayden returned to the series for the second season. The art department consisted of construction foreman Bob Huffman, set dressers Stacy Doran and Bruce Purcell, leadman Joseph W. Grafmuller, property master Angela M. Whiting, labor foreman Verne Hammond, art department coordinator Angela Trujillo, construction coordinator Curt Jones, set designer Yvonne Garnier - Hackl, stage foreman Tom Talley and paint foreman Alex Thompson. Joining the art department were set painter Shelley Adajian and assistant property masters Andrew Allen - King and Jeanne Bueche. However, the three new additions left the series after the production of the season finale, being temporarily replaced by Nicole Dome and T. Scott Elliott, who joined the team for two episodes. Sound editor Anthony Toretto, additional foley artist Mark McBryde, foley mixer Stacey Michaels, production sound mixer Brydon Baker III, foley artist Noel Vought, boom operator Kevin Maloney and sound re-recording mixers Todd Langer, Don Digirolamo, Pete Elia and Kurt Kassulke, the original members of the sound department, all returned for the second season. Production sound mixer Veda Campbell also returned, but departed after four episodes into the season, whereas assistant sound mixer Douglas J. Schulman was added to the crew for the first ten episodes of the season. Joining the production team in the sound crew were boom operator Kevin Maloney, sound mixer Cameron Hamza, Robert Marts and Mick Davies, with both Marts and Davies leaving the show after two episodes. The special effects team, which was led by coordinator Jason Gustafson, consisted of make - up artists Anthony Julio, who had been part of the production crew since the beginning of the series, and special effects foreman Ken Rudell. Part of the visual effects team were computer graphic artist Richard Also, visual effects supervisor Rick Cortes and matte artist Kristin Johnson. Whereas Cortes and Johnson joined the crew close to the season finale, Also was the only member of the visual effects team to have been in the crew since the beginning of the series. Writing and filming `` The weird thing about working in television is that you only see the people that you 're in scenes with. It 's not like you 're all running around the set together. So if you 're going to hang out together, you kind of have to make an effort. And I think people have families, people have lives. '' -- Sara Ramirez on her first days at Grey 's Anatomy The season was primarily filmed in Los Angeles, California. Fisher Plaza, which is the headquarters building for the media company Fisher Communications and Fisher 's ABC affiliated Komo radio and television stations for Seattle, is used for some exterior shots of Seattle Grace Mercy West Hospital, such as air ambulances landing on the Komo Television newscopter 's helipad. This puts Seattle Grace conveniently close to the Space Needle, which is directly across the street from Fisher Plaza, the Seattle Monorail, and other local landmarks. However, the hospital used for most other exterior and many interior shots is not in Seattle, are shot at the VA Sepulveda Ambulatory Care Center in North Hills, California. Most scenes are primarily taped in Los Feliz, Los Angeles, at the Prospect Studios, and the set occupies two stages, including the hospital pieces, but some outside scenes are shot at the Warren G. Magnuson Park in Seattle. Several props used are genuine medical supplies, including the MRI machine. Prior to being cast, Sara Ramirez was seen by ABC executives, in her Broadway performance of Spamalot, which garnered their attention. Due to their admiration, the network offered Ramirez a role on any ABC television series, of her choice, which ultimately led in her choosing Grey 's Anatomy. Ramirez further explained that at her initial audition, the producers liked her, and had intentions to add her to the show, but did not know who to cast her as. She also said she was in awe of how the executives said, `` Pick a show, any show '', a statement she deemed rare. Ramirez 's character was given recurring status in the second season, having been conceived as a love interest for George O'Malley. At Torres ' initial appearance on the show, she was disliked by fans, due to her getting in the way of O'Malley and Grey 's relationship. When asked of this, Ramirez said : `` You do run across a lot of people who are extremely invested in that story line. Obviously, I 've heard some negative stuff. '' Discussing Izzie Stevens ' relationship with Alex Karev, Katherine Heigl described her character as naive enough to believe she can save him, assessing that : `` Even when Alex was a complete dirtbag to her, she forgave him and gave him another chance. And he really screwed her over. '' Writer Stacy McKee described Izzie 's moving on from Alex to patient Denny Duquette as `` karma '', as Alex previously treated Izzie badly, yet as he begins to realize his true feelings, he is forced to watch her embark on a romance with Denny, regarded by her as `` undeniably handsome and totally charming ''. Series writer Blythe Robe commented on Izzie and Denny : `` I love the way Izzie lights up when she 's around him. I love their relationship because it 's so pure and honest and completely game free. '' Writer Elizabeth Klaviter noted at this time the way Izzie `` seems to be sacrificing her reputation because of her feelings for Denny. '' When Izzie deliberately worsened Denny 's condition to move him up the transplant list, series writer Mark Wilding questioned the morality of the actions, asking : `` Is Izzie bad for doing it ? Is she tremendously irresponsible ? She cut the wire for love so does that make her action understandable ? '' Series creator Shonda Rhimes discussed costuming choices in the scene which saw the interns gather around Denny 's deathbed, explaining : `` Meredith and George and Cristina and Callie and Alex are all dressed, not for a prom, but for a funeral. Everyone in dark colors, everyone dressed somberly. As if they were in mourning. Only Izzie is in happy pink. Only Izzie looks like she did n't know this was coming. '' Peter Horton, expressed that his plan of developing Chandra Wilson 's character, Miranda Bailey, was to focus on the similarities between her and the actress, noting that `` there 's not a mean bone in her body, but she 's solid and steady, like a rock. '' Wilson herself noted a significant evolution in her character 's personality, noting a transition from the cold attitude that was characteristic to her in the past, to a maternal outlook on her interns. She also noted a number of similarities between her and her character, describing how considers Miranda Bailey an alter ego of hers, rather than someone living inside her. Wilson also assessed that being a real - life human is what makes Bailey an appreciated character : `` She gets to be flawed, she gets to be tired, she can be cranky, she can be grumpy. '' Showrunner Shonda Rhimes explained that the idea of Miranda Bailey having a child was developed after Chandra Wilson had already been pregnant for six months. Cast member Kate Walsh deemed Wilson 's portrayal of her character `` sweet and wonderful '', naming her a professional : `` She makes you be a better actor, just by being there. '' She also described her performance during her character 's labor as `` heart - breaking, tender, powerful and wonderful '', noting how she managed to transform the strong character into `` a weak woman, struggling to fight the unusual situation ''. Fellow cast member James Pickens, Jr. described Wilson 's portrayal of Miranda Bailey as `` a breath of fresh air, literally and figuratively '', also noting how the force she delivers is mainly due to the start of her career being in theater. Horton also described the production process of the two - part story arc, which he stated to have been planning since the beginning of the series. He stated that the plot of the episodes had to `` fill the demands of the Super Bowl '', which was scheduled to air in the same night : `` We really wanted something different and Shonda ( Rhimes ) came up with the idea of this bomb, that we found simply outstanding ! '' Visual effects supervisor Scott Milnex noted how `` breaking down the story boards was really the key to getting all the departments to work together ''. He also assessed that the necessity to use Primacord, an element they had been trying to avoid, for the explosion scene proved excessively dangerous, and was ultimately replaced with wood and clothing material. He described the filming process by emphasizing the transition from mannequin to the real actor : `` When we filmed it, there was a moment, a fraction of a second, when we changed the body with the actor. '' Cast Main articles : List of Grey 's Anatomy cast members and List of Grey 's Anatomy characters Walsh became a series regular in the seventh episode of the season, after previous appearances in a guest star capacity. The second season had ten roles receiving star billing, out of whom nine were returning from the first season. All the actors who appear as series regulars portray physicians from the fictional Seattle Grace Hospital, specialized in surgery. Ellen Pompeo acted as Meredith Grey, the protagonist and the narrator of the series, a surgical intern who struggles to balance the difficulties of the competitive career she has chosen, with her troubled personal background. Sandra Oh portrayed highly competitive intern Cristina Yang, who suffers a miscarriage just as she starts accepting her upcoming motherhood. Katherine Heigl played intern Izzie Stevens, in a continuous struggle to be looked upon as a doctor, not the model she used to be. Justin Chambers acted as Alex Karev, who begins to develop an emotional side of his personality, after being introduced as arrogant and selfish. T.R. Knight played the role of intern George O'Malley, whose insecurity and lack of self - confidence evolve due to his unshared feelings for Meredith Grey. Chandra Wilson portrayed surgical resident and brilliant general surgeon Miranda Bailey, the mentor of the five interns, whose rudeness and cold attitude earns her the nickname `` The Nazi ''. James Pickens, Jr. portrayed Seattle Grace Hospital 's Chief of Surgery, Richard Webber, whose relationship with Meredith Grey 's mother, which occurred twenty - one years ago, threatens to ruin his marriage. Isaiah Washington played the role of attending physician and cardiothoracic surgeon Preston Burke, who learns that Cristina, with whom he had a sexual relationship, is pregnant with his child. Patrick Dempsey portrayed attending neurosurgeon Derek Shepherd, whose relationship with intern Meredith Grey has been the focal point of the series since its inception. Although originally conceived as a guest star with a five - episode story arc, Kate Walsh decided to extend her contract following positive reviews from critics and fans, resulting in her getting promoted to series regular status. Being the first addition to the original cast from the first season, Walsh began receiving star billing in the seventh episode of the season, portraying obstetrician - gynaecologist and world - class neonatal surgeon Addison Montgomery Shepherd, who comes in Seattle seeking reconciliation with her estranged husband, Derek Shepherd. Numerous supporting characters have been given expansive and recurring appearances in the progressive story line. Sara Ramirez appeared in a nine episode arc in the season, portraying orthopedic surgical resident Callie Torres, introduced and developed as a love interest for the character of George O'Malley. Steven W. Bailey is introduced in the recurring role of Joe, the Bartender, often being portrayed as a confidant of the surgeons of Seattle Grace Hospital. Chris O'Donnell portrayed Veterinary physician Finn Dandridge, who became a love interest for Meredith Grey. Renowned surgeon Ellis Grey, Meredith 's mother, who is suffering from Alzheimer 's disease, continues her recurring role from the first season, being portrayed by Kate Burton. Brooke Smith portrayed Erica Hahn, a cardiothoracic surgeon at Seattle Presbyterian Hospital, who is revealed to have been a rival of Preston Burke ever since they attended medical school together. Jeffrey Dean Morgan appears in six episodes throughout the season, portraying patient Denny Duquette, who begins a relationship with Izzie Stevens, but ultimately dies following an unsuccessful heart transplant surgery. Loretta Devine acted as Adele Webber, Richard 's wife, who is revealed to have been aware of her husband 's affair since its inception. Other guest stars include Sarah Utterback in the role of nurse Olivia Harper, love interest of both George O'Malley and Alex Karev, Kali Rocha portraying fifth - year resident Sydney Heron, who replaces Miranda Bailey temporarily when she takes a maternity leave, Jeff Perry portraying Meredith Grey 's father, Thatcher Grey, Mare Winningham in the role of Susan Grey, Tsai Chin in the role of Helen Yang Rubenstein, Cristina 's mother, Mandy Siegfried portraying Molly Grey Thompson, Meredith 's half - sister and Tessa Thompson portraying Camille Travis, Richard Webber 's niece, Christina Ricci portraying paramedic Hannah Davies, and Kyle Chandler in the role of Dylan Young, head of the bomb squad. Eric Dane, who would be promoted to a series regular in the third season, appeared in the eighteenth episode, portraying attending physician, otolaryngologist and plastic surgeon Mark Sloan, Addison Montgomery 's former lover, whose affair with her is presented as the reason behind the estrangement of her husband, Derek Shepherd. Main Cast Ellen Pompeo as Dr. Meredith Grey Sandra Oh as Dr. Cristina Yang Katherine Heigl as Dr. Izzie Stevens Justin Chambers as Dr. Alex Karev T.R. Knight as Dr. George O'Malley Chandra Wilson as Dr. Miranda Bailey James Pickens Jr. as Dr. Richard Webber Kate Walsh as Dr. Addison Montgomery - Shepherd ( From Episode 7 ) Isaiah Washington as Dr. Preston Burke Patrick Dempsey as Dr. Derek Shepherd Reception Critical response Ellen Pompeo was nominated for Best Actress at the Golden Globes. The season opened up to critical acclaim with many critics calling it `` one of the best shows on TV '' and was included in the top ten for numerous 2006 `` best of television '' lists. Also the fame of the show skyrocketed during the season The A.V. Club called the show a `` pokemon '' and `` one of the best TV shows around, burning through plot points at a furious clip, swooning romanticism, at embracing the kind of deeply earnest, intensely felt romance that made the show 's relationships so great. Meredith 's famous `` Pick me, choose me, love me '' speech is corny, to be sure, but it 's got tremendous rhythm and absolute conviction... season two of Grey 's was a comet. '' Todd Gilchrist of IGN Entertainment expressed hope in the further development of the series, noting the complex backgrounds of each character as being the series ' focal point. He noted that the ensemble, composed of `` countless comely females and enough strong, competitive males '' remains outstanding in prime time, being iconic, due to the vast interpretations regarding the main cast. Whereas Gilchrist acknowledged that the show gives the impression of it being only for women, he stated that he can attest to its universal, equal - opportunity appeal, assessing that the show `` explores the medical world with both a sense of testosterone - fueled intensity and estrogen - laced sensitivity '' and deserved to have viewers from both genders, championing its merits. In response to the bomb story arc, he called the two episodes `` juicy '', while assessing that they `` followed a story line that not only explained the series up to that point, but featured all of the characters in their more or less purest from ''. Gilchrist provided an outlook on each character, describing Grey as a `` prodigiously talented but insecure surgeon, waylaid by her love for attending Derek Shepherd '', while stating that Yang, `` an aggressively ambitious intern '' lacks knowledge on any topic, except medicine, comparing her to boyfriend Burke, described as her opposite. In response to George O'Malley's story line, he noted how his sensitive personality constantly results in difficulty in his path to becoming a proper surgeon. He also expressed excitement in the doors opened by the previous season 's cliffhanger, seeing the arrival of Montgomery ( Walsh ) as `` certainly speaking to the show 's focus on relationships over the nuts and bolts of being a surgeon '', while praising Rhimes for continuing to `` merge those disparate elements in the way that does, or at least should be a source of enthusiasm for both men and women, creating an atmosphere both professional and intimately personal, often at the same time ''. `` Overall, the show is terrific. Indeed, one of the best currently on television. While it remains to be seen what the creators do with it, now that it 's become an outright event program, the season demonstrates that Rhimes and co. know what to do with the opportunities presented them. But that just leaves the larger question : do you know what to do with the opportunities presented to you ? Because whether you 're male or female, this is the kind of entertainment that small - screen devotees and folks fed up with television need to see. '' -- Todd Gilchrist of IGN Entertainment Noting the realism in the writing for the series, Gilchrist stated : `` It 's as if Rhimes and Co. harnessed the sublime and the mundane of our daily experiences, that strange sense of drama that emerges from even the most unimportant daily conflicts, and it transported it on a world that is legitimately fraught with life and death decisions. '' However, he expressed disappointment in the end of the second season, which he deemed surprisingly less strong, compared to the `` powerful '' first half and the `` immaculate '' first season, describing Stevens ' `` awkward and self - destructive '' relationship with a patient as a way to `` slow episodes to a screeching halt with maudlin and painfully underdeveloped turns towards melodrama '', while expressing the predictability of Duquette 's death. Gilchrist stated in response to Stevens ' development in the last part of the second season : `` Izzie 's descent into abject hysteria, which followed her season - long sanctimoniousness about everything, actually made me want something terrible to happen to her too. '' He described how some episodes were not among the show 's strongest, noting that the some plot lines created poignancy, and connected in an unfamiliar way. The reviews have stood the test of time and the season still remains a huge critical favorite. Entertainment Weekly reviewing the tenth season of the show acknowledged that, `` the second season is still the show 's best season to date. '' The site added, `` I do want to talk about what season 10 could learn from what I believe is the show 's best season to date : season 2. '' calling in all the signature elements of the show that it did the best with listing all the best moments from the season, `` the elevator '', `` the walkway '', `` Joe 's bar, '' Meredith 's `` Pick me '' speech ``. and the `` memorable patients '' adding, `` I want two people stuck on a pole ( Into You Like a Train ) or two Amish best friends having to say goodbye, and I want those stories to be given ample time to resonate. More than anything, I want them to affect our doctors in heartbreaking and beautiful ways. '' Eyder Peralta of The Houston Chronicle was critical of Izzie 's ethics in cutting Denny 's LVAD wire, writing that she `` should not be practising medicine '' and stating : `` That 's the reason I do n't watch Grey 's Anatomy, anymore, because the super hot blond chick can make an earth - shattering, fatal decision and she does n't get canned. '' Regarding the second season, Kevin Carr from 7M Pictures said `` Rhimes really just put Scrubs, E.R., Sex and the City and even a dash of The Love Boat in a blender and poured out Grey 's Anatomy. '' Also in regard to the second season, Christopher Monfette of IGN TV said `` (... ) The second season of this medical drama expertly wove its signature elements of complex relationships, whimsical banter and challenging life - lessons - all to a montage - fetish, indie - rock soundtrack ''. Awards and nominations In 2006, the series won the Golden Globe for `` Best Drama Series ''. Sandra Oh won the 2005 Golden Globe Award for `` Best Supporting Actress in a Series, Miniseries, or TV Film '' and the 2006 Screen Actors Guild Award for `` Outstanding Performance by a Female Actor in a Drama Series '' for her portrayal of Cristina Yang in the show 's second season. Ellen Pompeo and Patrick Dempsey were also nominated for the Best Actress in a Drama Series and Best Actor in a Drama Series respectively at the 63rd Golden Globe Awards. In 2006, casting directors Linda Lowy and John Brace won a Primetime Emmy Award for `` Outstanding Casting for a Drama Series ''. The Grey 's Anatomy cast won Best Ensemble in a Television Series at the 2006 Satellite Awards. At the Screen Actors Guild Awards, the cast was nominated for `` Outstanding Performance by an Ensemble in a Drama Series ''. Isaiah Washington was awarded `` Outstanding Actor in a Drama Series '' at the NAACP Image Awards in 2006. Krista Vernoff received an Emmy nomination for Outstanding Writing for a Drama Series for the sixth episode of the season. The sixteenth and seventeenth episodes of the season secured writer Shonda Rhimes a 2006 Primetime Emmy Award nomination in the Outstanding Writing for a Drama Series category. Ratings The first five episodes of the season were initially planned to be within the first season with the episode `` Bring the Pain '' as the season one finale. According to Rhimes, after airing the ninth episode of the show, the ratings, the timeslots and the really great audience meant that they have to end the season with that episode, and the cliffhanger with the coming of Derek 's estranged wife fit perfectly. The season received positive critics and reception, and this season performed better than the previous one. Due to the success of the first season, Grey 's Anatomy took over the Sunday night timeslot along with Desperate Housewives, replacing Boston Legal. The second season averaged 21.07 million viewers, making it the highest - rated season of the series to date. It was ranked the fifth in the 2005 - 2006 television season. The season also includes the series ' highest - rated episode, `` It 's the End of the World '' which was watched by 37.88 million viewers. Episodes See also : List of Grey 's Anatomy episodes No. overall No. in season Title Directed by Written by Original air date U.S. viewers ( millions ) 10 `` Raindrops Keep Falling on My Head '' Peter Horton Stacy McKee September 25, 2005 ( 2005 - 09 - 25 ) 18.98 Joe the bartender finds himself in the need of a very expensive standstill surgery that there is no way he 'll be able to afford. Much to Meredith 's discomfort, Addison requests her as her intern for the day. Still recovering from surgery, Dr. Webber asks George to be his `` eyes and ears '', but George finds it difficult to pass on any information. Cristina tells Meredith that she is pregnant without revealing the father. When Burke breaks off their relationship, she decides not to tell him either. Izzie and Alex 's personal bond grows closer as he shows a more emotional side of himself. 11 `` Enough Is Enough '' Peter Horton James D. Parriott October 2, 2005 ( 2005 - 10 - 02 ) 17.57 Adele cuts her vacation short to come and care for Dr. Webber who is still recovering from surgery. Cristina and Meredith both express a great deal of bitterness toward their past doctoral flames. After having worked with nurse Olivia all day, George admits that he likes someone else. Cristina, Alex and Izzie treat the victims from a car crash where the father needs a liver transplant, but his son does n't want to donate because of the way his father abuses his mother. Meredith and Bailey treats a man who has swallowed the heads of ten Judy dolls. George consults Derek when he believes that an organ donor is still alive. 12 `` Make Me Lose Control '' Adam Davidson Krista Vernoff October 9, 2005 ( 2005 - 10 - 09 ) 18.12 Ellis Grey is brought into the hospital for possible diverticulitis, and her Alzheimer 's condition becomes known to everyone. George is assigned to her case, but she refuses him to treat her, believing he 's her ex-husband Thatcher Grey. Alex and Meredith treat a young patient with an extreme blushing condition. Izzie defends her blossoming friendship with Alex to the others. Addison and Izzie try and save the life of a premature baby who was abandoned. To Burke 's shock, Cristina collapses in the O.R. and Addison has to remove her Fallopian tube, causing her baby to be aborted. Meredith tells Derek that hating him is exhausting and that she does n't want to do it anymore. 13 `` Deny, Deny, Deny '' Wendey Stanzler Zoanne Clack October 16, 2005 ( 2005 - 10 - 16 ) 18.28 Cristina is still recovering from her surgery while receiving a visit from her mother. Not wanting to rest in bed, she uninvitedly diagnoses Burke and Izzie 's patient with Münchhausen syndrome. Eager to seem fine, Cristina has refused to mourn all day, but in the end, she breaks down. Addison gives Derek divorce papers to sign, but he ca n't make up his mind. Alex asks Izzie on a date, but before their date he learns that he failed one of his medical board exams and will have to retake it and pass or give up surgery. Alex and Derek treat a man who claims to have shot himself in the head. Bailey treats a patient with cystic fibrosis who is very important to her and has been her patient since she was an intern. Ellis is still in the hospital and believes she is there working. George has been assigned to watching her but he keeps losing her. 14 5 `` Bring the Pain '' Mark Tinker Shonda Rhimes October 23, 2005 ( 2005 - 10 - 23 ) 18.00 Meredith and Derek have to use more than medicine when a young Hmong woman 's traditionalist, religious father forbids her to have a life - saving operation unless a shaman is called upon to `` retrieve her souls ''. George and Alex are trapped in an elevator with a patient in critical condition after a gunshot wound to the heart. Burke tells them they must perform the surgery because there is n't enough time. Burke hands Alex the scalpel through the elevator door, but Alex freezes. George steps up and successfully gets the patient to a stable condition and the rescue team gets them out. Izzie treats an old lady who seemingly has a heart attack on the same day every year, whilst Cristina treats a man who has to watch porn to handle his pain, and has to come up with a different way to manage it when the power cuts. Derek struggles with his decision to either try to repair his marriage with Addison or divorce her and start a new life with Meredith. After trying to play it cool, Meredith breaks down and asks Derek to choose her. Ellis is discharged from the hospital. 15 6 `` Into You Like a Train '' Jeff Melman Krista Vernoff October 30, 2005 ( 2005 - 10 - 30 ) 16.67 Meredith nervously awaits a final decision from Derek at Joe 's bar, but her fear is interrupted when a train crash brings several seriously injured patients to the hospital and the interns are paged back to work. Two patients were seriously injured in the train and were both impaled by a long pole and are stuck together face to face. The doctors must make a tough decision because they realize that only one patient can survive the surgery. Meredith realizes that Derek has chosen Addison, and she is crushed. Alex fails to notice the friend of his patient is bleeding internally and she eventually dies from her injuries. Cristina works on a foot that has been sliced off of a patient, however things get complicated when she and Webber realize that it does n't belong to who they thought it did. Addison and Izzie work with two pregnant women who are best friends. Addison sees great potential in Izzie, who must decide whether her loyalty as Meredith 's friend outweighs professional gain. Derek clears Webber for surgery. 16 7 `` Something to Talk About '' Adam Davidson Stacy McKee November 6, 2005 ( 2005 - 11 - 06 ) 18.13 Cristina, Izzie and Meredith aggressively pursue the case of Shane, a male patient who seems to have a hysterical pregnancy, which fascinates the entire medical staff. Meredith becomes angry because everyone in the hospital is treating the patient like a sideshow and invading his privacy. She relates to him because the entire hospital staff seems to be gossiping about her and Derek. A sheltered young patient inspires Alex to better express his feelings for Izzie. Alex finds her at Joe 's and sweeps her into a dramatic kiss that knocks her socks off. George and Burke treat a patient with extensive scar tissue around her heart, who is constantly complaining at her husband. Burke and Cristina discuss whether to go public about their relationship, whilst Addison and Derek encounter hurdles as they attempt to rebuild theirs. 17 8 `` Let It Be '' Lesli Linka Glatter Mimi Schmir November 13, 2005 ( 2005 - 11 - 13 ) 19.74 Derek and Addison Shepherd 's professional relationship is challenged when their friends from Manhattan come to Seattle Grace seeking a radical, preemptive operation to avoid breast and ovarian cancer. Meanwhile, George ca n't understand why a patient who fell five stories does n't seem happy to have survived, and an elderly gentleman makes a difficult decision upon learning that his wife has only a few months to live. Cristina and Burke try to have a `` normal '' date, but the event takes a change after someone collapses in the restaurant. Dr. Webber is disappointed by Bailey 's fellowship decision -- until he learns her reason : that she is pregnant. 18 9 `` Thanks for the Memories '' Michael Dinner Shonda Rhimes November 20, 2005 ( 2005 - 11 - 20 ) 20.33 The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner. George endures the family tradition of hunting turkeys with his father and brothers. Having sneaked off to the hospital instead of helping Izzie out, Meredith treats a patient who 's been in a vegetative state for 16 years. Addison asks Derek to have sex with her again, but he stands her up to help with Meredith 's patient. Burke helps Izzie to prepare the Thanksgiving meal. Just as Izzie is about to give up on anyone showing up for dinner, George and Cristina come back, while Meredith celebrates with a one - night stand at Joe 's bar. 19 10 `` Much too Much '' Wendey Stanzler Gabrielle Stanton & Harry Werksman, Jr. November 27, 2005 ( 2005 - 11 - 27 ) 19.59 Meredith is mortified when her one - night stand shows up at the hospital suffering from priapism and needing medical attention. Izzie, Addison and Derek are assigned to a case where a woman carrying quintuplets is overwhelmed by numerous medical issues as she navigates her high - risk pregnancy. Alex 's shortcomings frustrate Izzie, especially when she catches Alex and Olivia having sex. On the other hand, Alex again shows his incompetence in treating one of his patients by administering the wrong dosage. Cristina reluctantly shows Burke where she lives. 20 11 `` Owner of a Lonely Heart '' Daniel Minahan Mark Wilding December 4, 2005 ( 2005 - 12 - 04 ) 20.59 Cristina has little sympathy for Constance Ferguson, a prison inmate who jeopardizes her health just to get out of solitary confinement. The interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges. Derek and Addison argue over their living arrangements. George treats a man by using leeches, whilst Alex continues to treat the patient he accidentally put into a coma. Addison decides to teach Izzie a very painful lesson which she too once received from the chief, wanting Izzie to know the consequences of being too attached to her patients. Izzie argues with Meredith after seeing her help Alex, and to mend their friendship they buy a dog together. 21 12 `` Grandma Got Run Over by a Reindeer '' Peter Horton Krista Vernoff December 11, 2005 ( 2005 - 12 - 11 ) 15.70 A young boy needs a heart transplant but does n't seem to want it, and an argument over his treatment exposes major philosophical differences between Burke and Cristina. Meanwhile, when the interns rally to help Alex prepare to re-take his exam, Izzie feels betrayed and Meredith has to remind her of the true spirit of the Christmas holiday. George has to deal with the family of a woman whose surgery for bleeding ulcers keeps getting postponed for more important surgeries, much to their contempt, whilst Bailey has to perform several surgeries when Webber is forced to leave her on her own. Derek performs brain surgery on the patriarch of a mixed Jewish / Christian family who discuss celebrating Chrismukkah, but is n't in a festive mood despite a reconciliation with his wife. 22 13 `` Begin the Begin '' Jessica Yu Kip Koenig January 15, 2006 ( 2006 - 01 - 15 ) 18.97 Dr. Webber enforces an 80 - hour - per - week maximum rule for the interns. Derek wants to enroll Ellis in an experimental treatment for Alzheimer 's, but Meredith does n't want his help and Derek needs Dr. Webber to intervene. Alex treats a writer who ate his entire novel. Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient awaiting a heart transplant. Bailey goes to retrieve Denny 's heart, taking Cristina along for the ride. Meanwhile George and Addison treat Bex, a young teen who is intersex. 23 14 `` Tell Me Sweet Little Lies '' Adam Davidson Tony Phelan & Joan Rater January 22, 2006 ( 2006 - 01 - 22 ) 21.04 The truth is in short supply as Meredith and Cristina lie to each other about the status of their relationships. Derek and Cristina treat a guitarist who lost three of his fingers, but she is angry with Derek since he has Meredith calling him McDreamy again. Meredith and Burke treat a recently married woman with persistent heart problems, whose happiness turns out to be a symptom. Cristina ' kinda ' moves in with Burke, whilst George threatens to move out over Meredith 's dog and in the end Meredith reluctantly gives him to Derek and Addison. George is given the unpleasant task of discharging an elderly patient who refuses to leave the hospital despite no longer being sick. Bailey, Alex and Izzie treat a competitive eater who is presented with a tear in the lining of her esophagus. Alex is so nervous about the results of his exam that he eventually asks Izzie to open them for him. Bailey is put on maternity leave. 24 15 `` Break on Through '' David Paymer Zoanne Clack January 29, 2006 ( 2006 - 01 - 29 ) 18.44 Amidst a strike by the nurses, Meredith revives an elderly patient without knowing she 's not supposed to. As the patient dies with her friends at her side, Meredith realizes she does n't want her mother to die alone, and allows the chief to continue visit her, something she initially was upset with. George ends up on the nurses ' side. Izzie treats a pregnant teenager with whom she has much in common, and her interfering upsets the patient 's mother, Izzie also reveals to the patient that she has a daughter. Cristina is irritated with the perky new resident, Sydney, and asks for Burke 's intervention when Sydney attempts a risky procedure to save a woman 's infected leg from amputation. 25 16 `` It 's the End of the World '' Peter Horton Shonda Rhimes February 5, 2006 ( 2006 - 02 - 05 ) 37.88 Meredith has a feeling and George and Izzie have to call in Cristina to get her out of bed. A paramedic brings in a man with live ammunition in his chest ; her hand is the only thing preventing an explosion. Bailey goes into labor and Derek and Cristina perform surgery on Bailey 's husband who crashed the car on his way in. Izzie initiates things with Alex. When the anesthesiologist leaves the paramedic alone in the O.R., she panics and pulls her hand out of the patient - but Meredith takes her place. 26 17 `` As We Know It '' Peter Horton Shonda Rhimes February 12, 2006 ( 2006 - 02 - 12 ) 25.42 Without her husband by her side, Bailey refuses to have the baby and George works with Addison to convince her to. George also treats the paramedic who fled after finding her hiding in a stairwell. Dr. Webber 's stress causes an anxiety attack that brings Adele to the hospital. Meredith removes the explosive from the patient, but it explodes and kills Dylan, the chief of the bomb squad. Burke and Derek overcome their initial rivalry and call each other by their first names. Cristina says `` I love you, too '' to a sleeping Burke. Derek comes visiting Meredith after she nearly dies and Meredith tells him that she ca n't remember their last kiss. 27 18 `` Yesterday '' Rob Corn Story by : Mimi Schmir Teleplay by : Krista Vernoff February 19, 2006 ( 2006 - 02 - 19 ) 24.36 Dr. Mark Sloan arrives in Seattle to try to convince Addison to continue their relationship, and is greeted with a punch from Derek. Dr. Webber allows Sloan to assist Derek in a risky surgery to fix a teenage patient with facial tumors. Burke learns that Cristina still leases her apartment. Izzie treats a patient with spontaneous orgasms. Meredith treats a man who believes he is going to die so he has her record him saying hateful things to everyone he knows. Later, Meredith goes to see her father for the first time in twenty years and is left unsatisfied with his answers about the past. George finally tells Meredith how he feels about her. 28 19 `` What Have I Done to Deserve This ? '' Wendey Stanzler Stacy McKee February 26, 2006 ( 2006 - 02 - 26 ) 24.76 Following their sexual encounter, Meredith and George avoid each other at work, and George ends up falling down a stairwell and dislocating his shoulder. Frequent heart patient Denny is readmitted and grows closer to Izzie, causing Alex to be jealous. Meredith, Derek, and Alex treat a kid with a head injury. Burke, Cristina, and George treat a man about to get married who has an aortic aneurysm. Bailey 's maternity leave is disrupted when Addison secretly asks her to help treat her allergic reaction to poison oak. George moves in with Burke and Cristina and catches the eye of ortho resident Dr. Callie Torres. 29 20 `` Band - Aid Covers the Bullet Hole '' Julie Anne Robinson Gabrielle Stanton & Harry Werksman, Jr. March 12, 2006 ( 2006 - 03 - 12 ) 22.51 After Dr. Bailey is called into surgery, Cristina is forced to watch baby Tucker for the remainder of the day. Meanwhile, George and Meredith are still on the outs as she confides in Derek with her problem. Meredith treats a woman with a fork stuck in her neck. Izzie continues to warm up to Denny who is having problems breathing. George and Callie further their flirtations over a teenaged patient who decides to chop off his own finger after Callie refuses to do it for him. Addison treats a pregnant woman, whose husband keeps hitting on her. Burke shows a preference for living with George over Cristina, and Addison gets a long - awaited admission from Derek that shows some hope for their marriage after all. 30 21 `` Superstition '' Tricia Brock James D. Parriott March 19, 2006 ( 2006 - 03 - 19 ) 21.13 When a series of deaths occur at Seattle Grace, the uncanny events bring out the doctors ' superstitious sides. Four deaths in the morning implies that three more deaths are due for the day. This makes Izzie nervous about Denny 's surgery, and a jealous Alex informs Denny of the likelihood of his death, prompting Izzie to completely end their relationship. Meredith and Bailey treat a woman who claims to have been struck by lightning, but the patient keeps lying about the true cause of the injury. Cristina treats a patient in a car accident who has OCD. Meanwhile, Derek and Addison discuss making a more permanent living arrangement, and Dr. Webber treats a former sponsor from his Alcoholics Anonymous group. George is tasked with stealing back one of Burke 's caps from Cristina. Izzie kisses Denny after he survives his surgery. 31 22 `` The Name of the Game '' Seith Mann Blythe Robe April 2, 2006 ( 2006 - 04 - 02 ) 22.35 Bailey worries Dr. Webber is mommy - tracking her and becomes Derek 's intern for the day. George begins a relationship with Callie and finds her living in the hospital. Meredith takes up knitting -- and a vow of celibacy. Cristina competes with Webber during classroom exercises. Burke tries to teach Alex a lesson about bedside manner, but it 's a lesson that falls on deaf ears. Izzie tries to get George to move back into the house. George discovers that his and Addison 's patient is Meredith 's half - sister. Meredith meets Doc 's vet, and takes a shine to him. 32 23 `` Blues for Sister Someone '' Jeff Melman Elizabeth Klaviter April 30, 2006 ( 2006 - 04 - 30 ) 20.76 Izzie grills George about the personal details of his life, and under instructions from Derek, tries to get a divorce lawyer to have a seizure so he can operate on her. Addison and Alex treat a pregnant woman who is expecting her seventh child, and face a difficult decision when the woman requests her tubes be tied off - record in order for her to avoid telling her very religious husband that she does n't want to have any more children. Burke performs surgery on his musical hero who wants a pacemaker removed as it has ruined his ability to play the violin. Meredith learns from Denny that life is too short to follow the rules, and decides to abandon her knitting and accept a date with Doc 's vet. George moves back in with Izzie and Meredith. Derek finally agrees to have hot sex with Addison. 33 24 `` Damage Case '' Tony Goldwyn Mimi Schmir May 7, 2006 ( 2006 - 05 - 07 ) 21.99 A family is involved in a car accident caused by a surgical intern from another hospital. The young pregnant wife has massive injuries and eventually dies, though Alex performs a Caesarean section to save the baby. Derek is angry at Meredith after he sees her at the vet 's. Burke is angry at Cristina after she fell asleep during sex the previous night. George does not stand up for Callie to his roommates and Denny is becoming angry at being stuck in bed with no end in sight. 34 25 `` 17 Seconds '' Daniel Minahan Mark Wilding May 14, 2006 ( 2006 - 05 - 14 ) 22.60 Part one of a three - part story arc. Gunshot victims from a nearby restaurant crowd Seattle Grace and the doctors are fully occupied. Cristina has an engaged couple who are arguing over him ducking behind her during the shooting, Meredith and Callie 's patient could lose his leg, and Derek and George have a 12 - week pregnant girl. Knowing that Derek is mad at Meredith for dating Finn, Addison yells at him in the hallways, not realizing everyone can hear. Meredith asks Callie for advice on bone cancer in dogs. Burke is still angry at Cristina and chooses Alex over her to go with him to retrieve a heart for Denny. When Izzie finds out that Denny is not about to get the heart, she takes the matter in her own hands. Callie professes her love to George, but before he can answer her, Izzie asks for his help with Denny, and he goes with her. As Burke races back to SGH to keep Izzie from doing something drastic, both Burke and Denny wind up in critical situations. 35 26 `` Deterioration of the Fight or Flight Response '' Rob Corn Tony Phelan & Joan Rater May 15, 2006 ( 2006 - 05 - 15 ) 22.50 Part two of a three - part story arc. The interns help Izzie keep Denny alive after she 's cut his left ventricular assist device ( LVAD ) wire. Derek must perform surgery on Burke 's shoulder and risk doing irreparable damage to the nerves. Cristina freezes in the O.R. during Burke 's surgery. Webber discovers his niece 's cancer has returned. Adele reveals to Webber that she knew about his affair with Ellis Grey. Alex fights for Denny 's heart at Mercy West, eventually offering Dr. Hahn the chance to scrub in at the surgery as Burke has been shot. Before surgery, Denny asks Izzie to marry him. However, after the heart has been inserted, it does not beat and back in Derek 's OR, Burke still can not move his fingers. 36 27 `` Losing My Religion '' Mark Tinker Shonda Rhimes May 15, 2006 ( 2006 - 05 - 15 ) 22.50 Part three of a three - part story arc. The interns are pulled into Dr. Webber 's office for interrogation regarding the LVAD wire situation. None of them reveal the truth, protecting Izzie, but Meredith confronts Dr. Webber over his affair with her mother. Dr. Webber tells them all that they are off surgery, and they are to give his niece a prom. Burke finds a tremor in his right hand. Meredith and Derek make the decision to put Doc to sleep. Izzie accepts Denny 's marriage proposal. During the prom, Derek and Meredith reunite in an exam room. The interns find Izzie lying in bed clinging to Denny, who has died from a stroke. Izzie leaves Seattle Grace, and on her way out confesses to Dr. Webber that she cut the LVAD wire and that she quits the program. Meredith remains torn on who she should follow : Derek or Finn. DVD release The second season was officially released on DVD in Region 1 on September 12, 2006, almost two weeks before the third season premiere which aired on September 21, 2006. Under the title Grey 's Anatomy : The Complete Second Season -- Uncut, the box set consists of episodes with Dolby Digital 5.1 surround sound and widescreen format. It also contained extras available only on DVD, including extended episodes, interviews with cast and crew members, footage from behind the scenes and unaired scenes cut from the aired episodes. The same set was released in Region 4 on January 10, 2007, four months after its original release in the United States, whereas its first release date in Region 2 was May 28, 2007, being made available first in the United Kingdom. The UK set contained the last twenty - two episodes of the season, due to the first five being released on the first season DVD. The season has not been released on Blu - ray disc in any region. The DVD box set is currently no. 708 in Movies and TV on Amazon.com and no. 2670 in Film and TV on Amazon.co.uk. Grey 's Anatomy : The Complete Second Season - Uncut Set Details Special Features 27 episodes ( 4 extended ) 6 - disc set 1.78 : 1 aspect ratio English ( Dolby Digital 5.1 Surround ) Subtitles : English, French, Spanish Four Extended Episodes -- Expanded and Uncut The Softer Side of Dr. Bailey -- Up - Close Interview With Chandra Wilson The Doctors Are In -- Stars Answer Fans ' Most Burning Questions Deleted Scenes Exclusive Set Tour Creating `` Pink Mist '' -- Anatomy Of A Special Effect Grey 's Anatomy on Jimmy Kimmel Live ! Release Dates Region 1 Region 2 Region 4 September 12, 2006 May 28, 2007 January 10, 2007 References Jump up ^ `` ABC Renames Television Studio ''. ABC. Walt Disney. Retrieved May 10, 2012. ^ Jump up to : `` Grey 's Anatomy Full Cast and Crew ''. imdb.com. Retrieved June 14, 2012. ^ Jump up to : Yuan, Jada ( September 18, 2006 ). `` Belle Curves : Sara Ramirez ''. New York Magazine. Retrieved June 18, 2012. Jump up ^ Grey 's Anatomy Season One DVD : Commentary Feature. Buena Vista, ABC. 2005. Jump up ^ `` Filming Locations for Grey 's Anatomy ''. IMDb. Retrieved May 24, 2012. Jump up ^ Clarendon, Dan. `` Where Is Grey 's Anatomy Filmed, Anyway ? ''. The Cambio Network. Wetpaint. Retrieved May 24, 2012. Jump up ^ De Leon, Kris ( September 25, 2006 ). `` Sara Ramirez ''. BuddyTV. Retrieved June 18, 2012. Jump up ^ Sara Ramirez, Kate Walsh, Chandra Wilson, Oprah Winfrey ( April 5, 2008 ). Sara Ramirez Chandra Wilson Kate Walsh OP. Los Angeles, California : Oprah Winfrey. ^ Jump up to : Gans, Andrew ( November 16, 2005 ). `` Spamalot 's Ramirez Lands Role on TV 's `` Grey 's Anatomy '' ``. Playbill. Archived from the original on September 4, 2012. Retrieved June 18, 2012. Jump up ^ Bardin, Brantley ( November 2006 ). `` Katherine Heigl Gives Us Fever ''. Cosmopolitan. Hearst Magazines. Retrieved 9 May 2009. Jump up ^ McKee, Stacy ( 26 February 2006 ). `` From Stacy McKee, writer of `` What Have I Done To Deserve This ? '' ``. Grey Matter. ABC. Archived from the original on 19 December 2012. Retrieved 15 May 2009. Jump up ^ Robe, Blythe ( 3 April 2006 ). `` From Blythe Robe, writer of `` Name of the Game '' ``. Grey Matter. ABC. Archived from the original on 15 May 2009. Retrieved 15 May 2009. Jump up ^ Klaviter, Elizabeth ( 30 April 2006 ). `` From Elizabeth Klaviter, writer of `` Blues for Sister Someone '' ``. Grey Matter. ABC. Archived from the original on 15 May 2009. Retrieved 15 May 2009. Jump up ^ Wilding, Mark ( 14 May 2006 ). `` From Mark Wilding, writer of `` 17 Seconds '' ``. Grey Matter. ABC. Archived from the original on 15 May 2009. Retrieved 15 May 2009. Jump up ^ Rhimes, Shonda ( May 17, 2006 ). `` From Shonda Rhimes ( FINALLY )... ''. Grey Matter. ABC. Archived from the original on March 19, 2013. Retrieved May 15, 2009. ^ Jump up to : Grey 's Anatomy Season Two DVD : Commentary Feature. Buena Vista, ABC. 2006. ^ Jump up to : `` Grey 's Anatomy Cast and Crew Bios ''. ABC.com. Archived from the original on June 25, 2012. Retrieved June 20, 2012. ^ Jump up to : `` Kate Walsh ''. Ask Men. Retrieved June 20, 2012. Jump up ^ `` 17 Seconds ''. Grey 's Anatomy. Season 2. Episode 25. May 14, 2006. ABC. Jump up ^ `` Losing My Religion ''. Grey 's Anatomy. Season 2. Episode 27. May 15, 2006. ABC. Jump up ^ `` Losing My Religion ''. Grey 's Anatomy. Season 2. Episode 27. May 15, 2006. ABC. Jump up ^ `` Yesterday ''. Grey 's Anatomy. Season 2. Episode 18. February 19, 2006. ABC. Jump up ^ http://www.ign.com/articles/2006/09/14/greys-anatomy-season-2-uncut Jump up ^ http://www.avclub.com/article/sure-igreys-anatomyi-was-a-big-hit-but-was-it-good-99320 ^ Jump up to : Todd Gilchrist ( September 14, 2006 ). `` Grey 's Anatomy - Season 2 Uncut ''. IGN Entertainment. Retrieved June 26, 2012. Jump up ^ http://www.ew.com/article/2014/02/28/greys-anatomy-season-10 Jump up ^ Peralta, Eyder ( February 16, 2007 ). `` Tsk. Tsk. Ethics these days ''. Houston Chronicle. Hearst Corporation. Retrieved July 21, 2009. Jump up ^ `` Grey 's Anatomy - Season 2 ( 2006 ) ''. RottenTomatoes.com. Retrieved September 3, 2011. Jump up ^ `` ' 24, ' ' Grey 's Anatomy ' top Emmy noms ''. Quad City Times. Retrieved 1 December 2009. Jump up ^ Rhimes, Shonda. `` Shonda Discusses Episode ''. ABC. Grey 's Anatomy. Archived from the original on May 15, 2009. Retrieved May 12, 2012. Jump up ^ `` Season Program Rankings from 09 / 19 / 05 through 05 / 28 / 06 ''. ABC Medianet. May 28, 2006. Archived from the original on October 11, 2014. Retrieved May 19, 2010. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. September 27, 2005. Archived from the original on June 1, 2009. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. October 4, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. October 11, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. October 18, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. October 25, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. November 1, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. November 8, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. November 15, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. November 22, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. November 29, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. December 6, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. December 13, 2005. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. January 18, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. January 24, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. January 31, 2006. Archived from the original on July 28, 2014. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. February 7, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. February 14, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. February 22, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. February 28, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. March 14, 2006. Archived from the original on October 11, 2014. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. March 21, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. April 4, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. May 2, 2006. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. May 9, 2006. Archived from the original on June 1, 2009. Retrieved July 3, 2009. Jump up ^ `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. May 16, 2006. Archived from the original on May 28, 2010. Retrieved July 3, 2009. ^ Jump up to : `` Weekly Program Rankings ''. Medianet. American Broadcasting Company. May 23, 2006. Retrieved July 3, 2009. Jump up ^ `` Grey 's Anatomy Complete Second Season ''. Amazon.com. Retrieved May 12, 2012. Jump up ^ `` Grey 's Anatomy Season 2 ''. Amazon.com. Amazon.co.uk. Retrieved May 12, 2012. `` Grey 's Anatomy episodes - season 2 ''. Grey 's Anatomy Episode Guide. TV Guide. Retrieved January 26, 2010. `` Shows A-Z - grey 's anatomy on abc ''. the Futon Critic. Retrieved January 26, 2010. `` Grey 's Anatomy - Episode Guide ''. ABC. Retrieved January 26, 2010. Grey 's Anatomy episodes Season 1 `` A Hard Day 's Night '' `` If Tomorrow Never Comes '' Season 2 `` Into You Like a Train '' `` It 's the End of the World '' `` As We Know It '' `` Losing My Religion '' Season 3 `` Time Has Come Today '' `` I Am a Tree '' `` Great Expectations '' `` Wishin ' and Hopin ' '' `` Did n't We Almost Have It All ? '' Season 4 `` A Change Is Gonna Come '' Season 5 `` What a Difference a Day Makes '' `` Stand By Me '' `` Elevator Love Letter '' `` Now or Never '' Season 6 `` Good Mourning '' `` Goodbye '' `` I Always Feel Like Somebody 's Watchin ' Me '' `` Tainted Obligation '' `` Invasion '' `` I Saw What I Saw '' `` Give Peace a Chance '' `` Invest in Love '' `` I Like You So Much Better When You 're Naked '' `` Death and All His Friends '' Season 7 `` Song Beneath the Song '' Season 8 `` Flight '' Season 9 `` Going, Going, Gone '' `` Beautiful Doom '' `` Perfect Storm '' Season 10 `` Fear ( of the Unknown ) '' Season 11 `` I Must Have Lost it on the Wind '' `` Puzzle With a Piece Missing '' `` Got to Be Real '' `` Only Mama Knows '' `` Bend & Break '' `` Do n't Let 's Start '' `` One Flight Down '' `` How to Save a Life '' `` She 's Leaving Home '' `` Time Stops '' `` You 're My Home '' Season 12 `` Sledgehammer '' `` Guess Who 's Coming to Dinner '' `` Something Against You '' `` Things We Lost in the Fire '' `` The Sound of Silence '' `` Family Affair '' Season 13 `` True Colors '' Season 14 `` Danger Zone '' `` Personal Jesus '' Grey 's Anatomy Episodes Season 1 5 6 7 8 9 10 11 12 13 14 Characters ( cast members ) Meredith Grey Cristina Yang Izzie Stevens Alex Karev George O'Malley Miranda Bailey Richard Webber Preston Burke Derek Shepherd Addison Montgomery Mark Sloan Callie Torres Lexie Grey Erica Hahn Owen Hunt Sadie Harris Arizona Robbins Teddy Altman Jackson Avery April Kepner Amelia Shepherd Stephanie Edwards Maggie Pierce Nathan Riggs Other Awards and nominations Soundtrack Video game Private Practice Station 19 A Corazón Abierto ( Mexican telenovela ) A Corazón Abierto ( Colombian telenovela ) Portal Golden Globe Award for Best Television Series -- Drama 1960s Marcus Welby, M.D. ( 1969 ) 1970s Medical Center ( 1970 ) Mannix ( 1971 ) Columbo ( 1972 ) The Waltons ( 1973 ) Upstairs, Downstairs ( 1974 ) Kojak ( 1975 ) Rich Man, Poor Man ( 1976 ) Roots ( 1977 ) 60 Minutes ( 1978 ) Lou Grant ( 1979 ) 1980s Shōgun ( 1980 ) Hill Street Blues ( 1981 ) Hill Street Blues ( 1982 ) Dynasty ) ( 1983 ) Murder, She Wrote ( 1984 ) Murder, She Wrote ( 1985 ) L.A. Law ( 1986 ) L.A. Law ( 1987 ) thirtysomething ( 1988 ) China Beach ( 1989 ) 1990s Twin Peaks ( 1990 ) Northern Exposure ( 1991 ) Northern Exposure ( 1992 ) NYPD Blue ( 1993 ) The X-Files ( 1994 ) Party of Five ( 1995 ) The X-Files ( 1996 ) The X-Files ( 1997 ) The Practice ( 1998 ) The Sopranos ( 1999 ) 2000s The West Wing ( 2000 ) Six Feet Under ( 2001 ) The Shield ( 2002 ) 24 ( 2003 ) Nip / Tuck ( 2004 ) Lost ( 2005 ) Grey 's Anatomy ( 2006 ) Mad Men ( 2007 ) Mad Men ( 2008 ) Mad Men ( 2009 ) 2010s Boardwalk Empire ( 2010 ) Homeland ( 2011 ) Homeland ( 2012 ) Breaking Bad ( 2013 ) The Affair ( 2014 ) Mr. Robot ( 2015 ) The Crown ( 2016 ) The Handmaid 's Tale ( 2017 ) Producers Guild of America Award for Best Episodic Drama Northern Exposure, season 1 ( 1991 ) I 'll Fly Away, season 1 ( 1992 ) NYPD Blue, season 1 ( 1993 ) ER, season 1 ( 1994 ) Frasier, season 2 ( 1995 ) Law & Order, season 6 ( 1996 ) The Practice, season 2 ( 1998 ) The Sopranos, season 1 ( 1999 ) The West Wing, season 1 ( 2000 ) The West Wing, season 2 ( 2001 ) 24, season 1 ( 2002 ) Six Feet Under, season 2 ( 2003 ) The Sopranos, season 5 ( 2004 ) Lost, season 1 ( 2005 ) Grey 's Anatomy, season 2 ( 2006 ) The Sopranos, season 6, part II ( 2007 ) Mad Men, season 1 ( 2008 ) Mad Men, season 2 ( 2009 ) Mad Men, season 3 ( 2010 ) Boardwalk Empire, season 1 ( 2011 ) Homeland, season 1 ( 2012 ) Breaking Bad, season 5, part I ( 2013 ) Breaking Bad, season 5, part II ( 2014 ) Game of Thrones, season 5 ( 2015 ) Stranger Things, season 1 ( 2016 ) The Handmaid 's Tale, season 1 ( 2017 ) Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series ( 2000 -- 2009 ) 2000 : The West Wing, season 1 / season 2 Hill Janney Kelly Lowe Moloney Schiff Sheen Spencer Whitford 2001 : The West Wing, season 2 / season 3 Hill Janney Lowe Moloney Schiff Sheen Spencer Whitford 2002 : Six Feet Under, season 2 Ambrose Conroy Griffiths Hall Krause Rodríguez St. Patrick 2003 : Six Feet Under, season 3 Ambrose Conroy Foster Griffiths Hall Krause Macdissi Machado Rodríguez St. Patrick Taylor Wilson 2004 : CSI : Crime Scene Investigation, season 4 / season 5 Dourdan Eads Fox Guilfoyle Hall Helgenberger Petersen Szmanda 2005 : Lost, season 1 / season 2 Akinnuoye - Agbaje Andrews de Ravin Fox Garcia Grace Holloway Kelley D.D. Kim Y. Kim Lilly Monaghan O'Quinn Perrineau Rodriguez Somerhalder Watros 2006 : Grey 's Anatomy, season 2 / season 3 Chambers Dane Dempsey Heigl Knight Oh Pickens Pompeo Ramirez Walsh Washington Wilson 2007 : The Sopranos, season 6, part II Antonacci Bracco Falco Gandolfini Grimaldi Iler Imperioli Nascarella Schirripa Servitto Sigler Sirico Turturro Van Zandt Vincent 2008 : Mad Men, season 2 Batt Brie Gladis Hamm Hart Hendricks Jones Kartheiser Moses Moss Shipka Slattery Sommer Staton 2009 : Mad Men, season 3 Alemanni Batt Gilmore Gladis Hamm Harris Hendricks Jones Kartheiser Morse Moss Shipka Slattery Sommer Stanley Staton Complete list ( 1994 -- 1999 ) ( 2000 -- 2009 ) ( 2010 -- present ) Retrieved from `` https://en.wikipedia.org/w/index.php?title=Grey%27s_Anatomy_(season_2)&oldid=823164126 '' Categories : Grey 's Anatomy episodes 2005 American television seasons 2006 American television seasons Grey 's Anatomy seasons Hidden categories : Pages using deprecated image syntax Good articles Talk Contents About Wikipedia Wikiquote Deutsch Español Français Italiano Polski Português Română Edit links This page was last edited on 30 January 2018, at 17 : 01. 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Question: when did season 2 of greys anatomy air
Answer: commenced airing on the American Broadcasting Company (ABC) on September 25, 2005, and concluded on May 15, 2006