Butylated hydroxyanisole - wikipedia Butylated hydroxyanisole `` E320 '' redirects here. For the British high speed train, see British Rail Class 374. For the Italian locomotive, see FS Class E. 320. Butylated hydroxyanisole Names Preferred IUPAC name 2 - tert - Butyl - 4 - methoxyphenol and 3 - tert - butyl - 4 - methoxyphenol ( mixture ) Other names 2 - tert - Butyl - 4 - hydroxyanisole and 3 - tert - butyl - 4 - hydroxyanisole ( mixture ) BOA BHA tert - Butyl - 4 - hydroxyanisole ( 1, 1 - Dimethylethyl ) - 4 - methoxyphenol tert - Butyl - 4 - methoxyphenol Antioxyne B Identifiers CAS Number 25013 - 16 - 5 8003 - 24 - 5 9009 - 68 - 1 121 - 00 - 6 88 - 32 - 4 3D model ( JSmol ) Interactive image ChEBI CHEBI : 76359 ChEMBL ChEMBL502074 ChemSpider 23068 ECHA InfoCard 100.042. 315 E number E320 ( antioxidants,... ) PubChem CID 24667 UNII REK4960K2U InChI InChI = 1S / 2C11H16O2 / c1 - 11 ( 2, 3 ) 9 - 7 - 8 ( 13 - 4 ) 5 - 6 - 10 ( 9 ) 12 ; 1 - 11 ( 2, 3 ) 9 - 7 - 8 ( 12 ) 5 - 6 - 10 ( 9 ) 13 - 4 / h2 * 5 - 7, 12H, 1 - 4H3 Key : CZBZUDVBLSSABA - UHFFFAOYSA - N InChI = 1 / 2C11H16O2 / c1 - 11 ( 2, 3 ) 9 - 7 - 8 ( 13 - 4 ) 5 - 6 - 10 ( 9 ) 12 ; 1 - 11 ( 2, 3 ) 9 - 7 - 8 ( 12 ) 5 - 6 - 10 ( 9 ) 13 - 4 / h2 * 5 - 7, 12H, 1 - 4H3 Key : CZBZUDVBLSSABA - UHFFFAOYAZ SMILES O ( c1ccc ( O ) cc1C ( C ) ( C ) C ) C.O ( c1ccc ( O ) c ( c1 ) C ( C ) ( C ) C ) C Properties Chemical formula Molar mass 180.25 g mol Appearance waxy solid Density 1.0587 g / cm at 20 ° C Melting point 48 to 55 ° C ( 118 to 131 ° F ; 321 to 328 K ) Boiling point 264 to 270 ° C ( 507 to 518 ° F ; 537 to 543 K ) Solubility in water Insoluble in water Solubility freely soluble in ethanol, methanol, propylene glycol ; soluble in fats and oils Refractive index ( n ) 1.5303 at 589.3 nm Related compounds Related compounds Butylated hydroxytoluene Except where otherwise noted, data are given for materials in their standard state ( at 25 ° C ( 77 ° F ), 100 kPa ). N verify ( what is ? ) Infobox references Butylated hydroxyanisole ( BHA ) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2 - tert - butyl - 4 - hydroxyanisole and 3 - tert - butyl - 4 - hydroxyanisole. It is prepared from 4 - methoxyphenol and isobutylene. It is a waxy solid used as a food additive with the E number E320. The primary use for BHA is as an antioxidant and preservative in food, food packaging, animal feed, cosmetics, rubber, and petroleum products. BHA also is commonly used in medicines, such as isotretinoin, lovastatin, and simvastatin, among others. Contents 1 Antioxidant properties 2 Research 3 See also 4 References Antioxidant properties Since 1947, BHA has been added to edible fats and fat - containing foods for its antioxidant properties as it prevents rancidification of food which creates objectionable odors. Like butylated hydroxytoluene ( BHT ), the conjugated aromatic ring of BHA is able to stabilize free radicals, sequestering them. By acting as free radical scavengers, further free radical reactions are prevented. Research The U.S. National Institutes of Health report that BHA is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. In particular, when administered in high doses as part of their diet, BHA causes papillomas and squamous cell carcinomas of the forestomach in rats and Syrian golden hamsters. In mice, there is no carcinogenic effect, and even evidence of a protective effect against the carcinogenicity of other chemicals. When examining human population statistics, the usual low intake levels of BHA show no significant association with an increased risk of cancer. The State of California, has, however, listed it as a carcinogen. See also Anisole References Jump up ^ `` BHA and BHT ''. Retrieved Nov 20, 2009. Jump up ^ `` SciFinder -- Experimental properties for 121 - 00 - 6 ''. Retrieved Nov 20, 2009. Jump up ^ Hazardous Substances Database, National Library of Medicine ^ Jump up to : Lam, L.K. ; R.P. Pai & L.W. Wattenberg ( 1979 ). `` Synthesis and chemical carcinogen inhibitory activity of 2 - tert - butyl - 4 - hydroxyanisole ''. J Med Chem. 22 ( 5 ) : 569 -- 71. doi : 10.1021 / jm00191a020. PMID 458807. ^ Jump up to : Butylated Hydroxyanisole ( BHA ), CAS No. 25013 - 16 - 5, Report on Carcinogens, Eleventh Edition, National Institutes of Health Jump up ^ Botterweck AAM, Vergaen H, GoldBohm RA, KleinJans J, van den Brant PA ( 2007 ). `` Intake of Butylated Hydroxyanisole and Butylated Hydroxytoluene and Stomach Cancer Risk : Results from Analyses in the Netherlands Cohort Study ''. Food and Chemical Toxicology. 38 ( 7 ) : 599 -- 605. doi : 10.1016 / S0278 - 6915 ( 00 ) 00042 - 9. PMID 10942321. Jump up ^ `` Known Carcinogens and Reproductive Toxicants ( California Proposition 65 ) ''. Scorecard. Retrieved 2011 - 05 - 29. Retrieved from `` https://en.wikipedia.org/w/index.php?title=Butylated_hydroxyanisole&oldid=821682982 '' Categories : Phenols Endocrine disruptors Food antioxidants IARC Group 2B carcinogens Alkylphenols Tert - butyl compounds Hidden categories : Chemical articles with multiple compound IDs Multiple chemicals in an infobox that need indexing Chemical articles with multiple CAS registry numbers Articles without KEGG source Articles with changed CASNo identifier Articles with changed EBI identifier ECHA InfoCard ID from Wikidata E number from Wikidata Articles containing unverified chemical infoboxes Talk Contents About Wikipedia تۆرکجه Català Čeština Dansk Deutsch Español فارسی Français Italiano Lietuvių Magyar Nederlands 日本 語 Polski Português Русский Српски / srpski Srpskohrvatski / српскохрватски Suomi Svenska 中文 13 more Edit links This page was last edited on 22 January 2018, at 00 : 23. 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Question: what type of compound is the food additive bha
Answer: a mixture of two isomeric organic compounds