Wernicke 's area - wikipedia Wernicke 's area Wernicke 's area Approximate location of Wernicke 's area highlighted in grey Identifiers NeuroNames ancil - 252 NeuroLex ID Wernicke 's area Dorlands / Elsevier a_59 / 12151778 FMA 242178 Anatomical terms of neuroanatomy ( edit on Wikidata ) Wernicke 's area ( / ˈvɛərnɪkə / or / ˈvɛərnɪki / ; German : ( ˈvɛʁnɪkə ) ), also called Wernicke 's speech area, is one of the two parts of the cerebral cortex linked, since the late nineteenth century, to speech ( the other is Broca 's area ). It is involved in the comprehension or understanding of written and spoken language ( in contrast to Broca 's area that is involved in the production of language ). It is traditionally thought to be in Brodmann area 22, which is located in the posterior section of the superior temporal gyrus ( STG ) in the dominant cerebral hemisphere ( which is the left hemisphere in about 95 % of right handed individuals and 60 % of left handed individuals ). Damage caused to Wernicke 's area results in receptive, fluent aphasia. This means that the person with aphasia will be able to fluently connect words, but the phrases will lack meaning. This is unlike non-fluent aphasia, in which the person will use meaningful words, but in a non-fluent, telegraphic manner. Contents 1 Structure 2 Function 2.1 Right homologous area 2.2 Modern views 3 Clinical significance 3.1 Aphasia 4 References Structure Wernicke 's area is classically located in the posterior section of the superior temporal gyrus ( STG ) in the ( most commonly ) left cerebral hemisphere. This area encircles the auditory cortex on the lateral sulcus ( the part of the brain where the temporal lobe and parietal lobe meet ). This area is neuroanatomically described as the posterior part of Brodmann area 22. However, there is an absence of consistent definitions as to the location. Some identify it with the unimodal auditory association in the superior temporal gyrus anterior to the primary auditory cortex ( the anterior part of BA 22 ). This is the site most consistently implicated in auditory word recognition by functional brain imaging experiments. Others include also adjacent parts of the heteromodal cortex in BA 39 and BA40 in the parietal lobe. While previously thought to connect Wernicke 's area and Broca 's area, new research demonstrates that the arcuate fasciculus instead connects to posterior receptive areas with premotor / motor areas, and not to Broca 's area. Consistent with the word recognition site identified in brain imaging, the uncinate fasciculus connects anterior superior temporal regions with Broca 's area. Function Right homologous area Research using Transcranial magnetic stimulation suggests that the area corresponding to the Wernicke 's area in the non-dominant cerebral hemisphere has a role in processing and resolution of subordinate meanings of ambiguous words -- such as ' ' river ' ' when given the ambiguous word `` bank. '' In contrast, the Wernicke 's area in the dominant hemisphere processes dominant word meanings ( ' ' teller ' ' given ' ' bank ' ' ). Modern views Neuroimaging suggests the functions earlier attributed to Wernicke 's area occur more broadly in the temporal lobe and indeed happen also in Broca 's area. `` There are some suggestions that middle and inferior temporal gyri and basal temporal cortex reflect lexical processing... there is consensus that the STG from rostral to caudal fields and the STS constitute the neural tissue in which many of the critical computations for speech recognition are executed... aspects of Broca 's area ( Brodmann areas 44 and 45 ) are also regularly implicated in speech processing.... the range of areas implicated in speech processing go well beyond the classical language areas typically mentioned for speech ; the vast majority of textbooks still state that this aspect of perception and language processing occurs in Wernicke 's area ( the posterior third of the STG ). '' Support for a broad range of speech processing areas was furthered by a recent study done at University of Rochester in which American Sign Language native speakers were subject to MRIs while interpreting sentences that identified a relationship using either syntax ( relationship is determined by the word order ) or inflection ( relationship is determined by physical motion of `` moving hands through space or signing on one side of the body '' ). Distinct areas of the brain were activated with the frontal cortex ( associated with ability to put information into sequences ) being more active in the syntax condition and the temporal lobes ( associated with dividing information into its constituent parts ) being more active in the inflection condition. However, these areas are not mutually exclusive and show a large amount of overlap. These findings imply that while speech processing is a very complex process, the brain may be using fairly basic, preexisting computational methods. Clinical significance Human brain with Wernicke 's area highlighted in red Aphasia Wernicke 's area is named after Carl Wernicke, a German neurologist and psychiatrist who, in 1874, hypothesized a link between the left posterior section of the superior temporal gyrus and the reflexive mimicking of words and their syllables that associated the sensory and motor images of spoken words. He did this on the basis of the location of brain injuries that caused aphasia. Receptive aphasia in which such abilities are preserved is also known as Wernicke 's aphasia. In this condition there is a major impairment of language comprehension, while speech retains a natural - sounding rhythm and a relatively normal syntax. Language as a result is largely meaningless ( a condition sometimes called fluent or jargon aphasia ). While neuroimaging and lesion evidence generally support the idea that malfunction of or damage to Wernicke 's area is common in people with receptive aphasia, this is not always so. Some people may use the right hemisphere for language, and isolated damage of Wernicke 's area cortex ( sparing white matter and other areas ) may not cause severe receptive aphasia. Even when patients with Wernicke 's area lesions have comprehension deficits, these are usually not restricted to language processing alone. For example, one study found that patients with posterior lesions also had trouble understanding nonverbal sounds like animal and machine noises. In fact, for Wernicke 's area, the impairments in nonverbal sounds were statistically stronger than for verbal sounds. References Jump up ^ `` Aphasia : Signs & Symptoms ''. American Speech - Language - Hearing Association. Jump up ^ Kennison, Shelia ( 2013 ). Introduction to language development. Los Angeles : Sage. ^ Jump up to : Bogen JE, Bogen GM ( 1976 ). `` Wernicke 's region -- Where is it ? ''. Annals of the New York Academy of Sciences. 280 : 834 -- 43. Bibcode : 1976NYASA. 280... 834B. doi : 10.1111 / j. 1749 - 6632.1976. tb25546. x. PMID 1070943. Jump up ^ Démonet JF, Chollet F, Ramsay S, Cardebat D, Nespoulous JL, Wise R, Rascol A, Frackowiak R ( December 1992 ). `` The anatomy of phonological and semantic processing in normal subjects ''. Brain. 115 ( Pt 6 ) : 1753 -- 68. doi : 10.1093 / brain / 115.6. 1753. PMID 1486459. Jump up ^ DeWitt I, Rauschecker JP ( 2012 ). `` Phoneme and word recognition in the auditory ventral stream ''. Proceedings of the National Academy of Sciences. 109 ( 8 ) : E505 -- E514. Bibcode : 2012PNAS... 109E. 505D. doi : 10.1073 / pnas. 1113427109. PMC 3286918. PMID 22308358. Jump up ^ DeWitt I, Rauschecker JP ( 2013 ). `` Wernicke 's area revisited : parallel streams and word processing ''. Brain Lang. 127 ( 2 ) : 181 -- 91. doi : 10.1016 / j. bandl. 2013.09. 014. PMC 4098851. PMID 24404576. Jump up ^ Mesulam MM ( June 1998 ). `` From sensation to cognition ''. Brain. 121 ( Pt 6 ) : 1013 -- 52. doi : 10.1093 / brain / 121.6. 1013. PMID 9648540. Jump up ^ Bernal B, Ardila A ( September 2009 ). `` The role of the arcuate fasciculus in conduction aphasia ''. Brain. 132 ( Pt 9 ) : 2309 -- 16. doi : 10.1093 / brain / awp206. PMID 19690094. Jump up ^ Saur D, Kreher BW, Schnell S, Kümmerer D, Kellmeyer P, Vry MS, Umarova R, Musso M, Glauche V, Abel S, Huber W, Rijntjes M, Hennig J, Weiller C ( November 2008 ). `` Ventral and dorsal pathways for language ''. Proceedings of the National Academy of Sciences. 105 ( 46 ) : 18035 -- 18040. Bibcode : 2008PNAS... 10518035S. doi : 10.1073 / pnas. 0805234105. PMC 2584675. PMID 19004769. Jump up ^ Harpaz Y, Levkovitz Y, Lavidor M ( October 2009 ). `` Lexical ambiguity resolution in Wernicke 's area and its right homologue ''. Cortex. 45 ( 9 ) : 1097 -- 103. doi : 10.1016 / j. cortex. 2009.01. 002. PMID 19251255. Jump up ^ Poeppel D, Idsardi WJ, van Wassenhove V ( March 2008 ). `` Speech perception at the interface of neurobiology and linguistics ''. Philosophical Transactions of the Royal Society B. 363 ( 1493 ) : 1071 -- 86. doi : 10.1098 / rstb. 2007.2160. PMC 2606797. PMID 17890189. Jump up ^ Newman AJ, Supalla T, Hauser P, Newport EL, Bavelier D ( 2010 ). `` Dissociating neural subsystems for grammar by contrasting word order and inflection ''. Proceedings of the National Academy of Sciences. 107 ( 16 ) : 7539 -- 44. Bibcode : 2010PNAS... 107.7539 N. doi : 10.1073 / pnas. 1003174107. PMC 2867749. PMID 20368422. Jump up ^ Wernicke K. ( 1995 ). `` The aphasia symptom - complex : A psychological study on an anatomical basis ( 1875 ) ''. In Paul Eling. Reader in the History of Aphasia : From sasi ( Franz Gall to ). 4. Amsterdam : John Benjamins Pub Co. pp. 69 -- 89. ISBN 90 - 272 - 1893 - 5. Jump up ^ Dronkers NF. ; Redfern B B. ; Knight R T. ( 2000 ). `` The neural architecture of language disorders ''. In Bizzi, Emilio ; Gazzaniga, Michael S. The New cognitive neurosciences ( 2nd ed. ). Cambridge, Mass : MIT Press. pp. 949 -- 58. ISBN 0 - 262 - 07195 - 9. Jump up ^ Saygin AP, Dick F, Wilson SM, Dronkers NF, Bates E ( 2003 ). `` Neural resources for processing language and environmental sounds : evidence from aphasia ''. Brain. 126 ( Pt 4 ) : 928 -- 45. doi : 10.1093 / brain / awg082. PMID 12615649. Wikimedia Commons has media related to Wernicke 's area. Anatomy of the cerebral cortex of the human brain Frontal lobe Superolateral Prefrontal Superior frontal gyrus 6 8 Middle frontal gyrus 9 10 46 Inferior frontal gyrus : 11 47 - Pars orbitalis Broca 's area 44 - Pars opercularis 45 - Pars triangularis Superior frontal sulcus Inferior frontal sulcus Precentral Precentral gyrus Precentral sulcus Medial / inferior Prefrontal Superior frontal gyrus 6 Medial frontal gyrus 8 9 Paraterminal gyrus / Paraolfactory area 12 Straight gyrus 11 Orbital gyri / Orbitofrontal cortex 10 11 12 Ventromedial prefrontal cortex 10 Subcallosal area 25 Olfactory sulcus Orbital sulcus Precentral Paracentral lobule Paracentral sulcus Both Primary motor cortex Premotor cortex 6 Supplementary motor area 6 Supplementary eye field 6 Frontal eye fields 8 Parietal lobe Superolateral Superior parietal lobule 5 7 Inferior parietal lobule 40 - Supramarginal gyrus 39 - Angular gyrus Parietal operculum 43 Intraparietal sulcus Medial / inferior Paracentral lobule 5 Precuneus 7 Marginal sulcus Both Postcentral gyrus / Primary somatosensory cortex Secondary somatosensory cortex 5 Posterior parietal cortex 7 Occipital lobe Superolateral Occipital pole of cerebrum Lateral occipital gyrus 18 19 Lunate sulcus Transverse occipital sulcus Medial / inferior Visual cortex 17 Cuneus Lingual gyrus Calcarine sulcus Temporal lobe Superolateral Transverse temporal gyrus / Auditory cortex 41 42 Superior temporal gyrus 38 22 / Wernicke 's area Middle temporal gyrus 21 Superior temporal sulcus Medial / inferior Fusiform gyrus 37 Medial temporal lobe 27 28 34 35 36 Inferior temporal gyrus 20 Inferior temporal sulcus Interlobar sulci / fissures Superolateral Central ( frontal + parietal ) Lateral ( frontal + parietal + temporal ) Parieto - occipital Preoccipital notch Medial / inferior Longitudinal fissure Cingulate ( frontal + cingulate ) Collateral ( temporal + occipital ) Callosal sulcus Limbic lobe Parahippocampal gyrus anterior Entorhinal cortex Perirhinal cortex Postrhinal cortex Posterior parahippocampal gyrus Prepyriform area Cingulate cortex / gyrus Subgenual area 25 Anterior cingulate 24 32 33 Posterior cingulate 23 31 Isthmus of cingulate gyrus : Retrosplenial cortex 26 29 30 Hippocampal formation Hippocampal sulcus Fimbria of hippocampus Dentate gyrus Rhinal sulcus Other Supracallosal gyrus Uncus Amygdala Insular cortex Insular cortex General Operculum Poles of cerebral hemispheres Some categorizations are approximations, and some Brodmann areas span gyri. Retrieved from `` https://en.wikipedia.org/w/index.php?title=Wernicke%27s_area&oldid=777905390 '' Categories : Neurolinguistics Temporal lobe Cerebral cortex Hidden categories : Medicine infobox template using Dorlands parameter All articles with unsourced statements Articles with unsourced statements from January 2011 Talk Contents About Wikipedia Català Dansk Deutsch Ελληνικά Español فارسی Français 한국어 Bahasa Indonesia Italiano עברית Lietuvių Magyar Nederlands 日本 語 Norsk Polski Português Română Русский Simple English Suomi Svenska ไทย Українська West - Vlams 中文 Edit links This page was last edited on 30 April 2017, at 00 : 56. Text is available under the Creative Commons Attribution - ShareAlike License ; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia ® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. About Wikipedia

Question: what is the location of wernicke's area in the human brain
Answer: Brodmann area 22, which is located in the posterior section of the superior temporal gyrus (STG) in the dominant cerebral hemisphere