Clinical characteristics of the HBoV-infected children are shown in the Table. Children infected with only HBoV had mild-to-moderate fevers. Leukocyte counts and C-reactive protein levels were normal or moderately elevated. Chest radiographs obtained for 7 children showed abnormalities such as hyperinflation and interstitial infiltrates. Bronchiolitis was the major diagnosis. Dyspnea, respiratory distress, and cough were the most common respiratory symptoms observed. Four (44%) HBoV-infected children were born preterm, which suggests that these children have an increased susceptibility to HBoVassociated diseases. All children recovered and were discharged within 1 to 6 days.