The effect of Q7R on the extent of DNA fragmentation resulting from PEDV infection was examined. The incubation with Q7R or ribavirin up to 100 μg/ml concentration for 48 h did not induce DNA fragmentation in mock-infected Vero cells ( Figure 5A or 5B, lanes 2-4). PEDV infection induced DNA fragmentation in Vero cells 48 h after infection in the absence of compounds ( Figure 5A or 5B, lanes 5). In the presence of Q7R, the DNA fragmentation was not induced in a dose-dependent manner ( Figure 5B, lanes 6-8) . But, DNA fragmentation was somewhat decreased when Vero cells infected with PEDV were treated with ribavirin at concentration of 1 or 10 μg/ml for 48 h. Incubation with ribavirin of 100 μg/ml did not induce DNA fragmentation.