OFP-18-003 Detection of EGFR mutations and EML4-ALK rearrangements in lung adenocarcinomas using archived cytological slides E. Imyanitov * , N. Mitiushkina, A. Iyevleva, A. Poltoratskiy, A. Ivantsov, A. Togo, I. Polyakov, S. Orlov, D. Matsko, V. Novik * N.N. Petrov Institute of Oncology, St. Petersburg, Russia Objective: While the molecular analysis of EGFR and ALK in archival lung cancer tissues is relatively well established, the acceptability of genetic investigation of cytological material in clinical routine remains a subject of debate.