The Go analysis of the genomic study targeted the decreased immune function of T cells and immune receptor complex in PE patients, suggesting the occurrence of PE is closely related to the immune dysfunction. Statistical analysis revealed the mRNA expressions of genes associated with innate immunity and cytokines were markedly up-regulated and those related to the cellular immunity of T cells and NK cells significantly down-regulated. In addition, cytological experiment indicated 6 parameters related to immune function were abnormal in 53 of 56 VTE patients. The expressions of CD3 + and CD8 + were markedly reduced and the CD4 + /CD8 + ratio significantly increased. The number of CD16 + +56 + and CD19 cells was reduced. The results from cytological examination and genome analysis were consistent.