Objectives: The effects of intrastriatal administration of Gly to rats on relevant oxidative stress parameters were investigated. Methods: Thiobarbituric acid-reactive substances (TBA-RS), carbonyl formation, sulfhydryl content, reduced glutathione (GSH) levels, nitric oxide production and the activities of the antioxidant enzymes glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), superoxide dismutase (SOD) and glucose-6-phosphate dehydrogenase (G6PD) were measured in striatum from 30-day-old rats.