Objective: Placental angiogenesis anomalies play an important role in some complications of pregnancy development, including preeclampsia (PE). VEGF and its receptorsone of the key placental angiogenic factor. Aim: to evaluate patterns of VEGF and its receptors (VEGFRs 1, 2 and 3) expression in placentas from PE complicated pregnancies. Method: We performed complex morphological and immunohistochemical study of 9 term placentas from mild preeclampsia (mPE) cases (1st group), 6 term placentas from severe preeclampsia (sPE) cases (2nd group) and 10 term placentas from uncomplicated pregnancies (control group). Results: We revealed significantly increased syncitial VEGF expression levels in preeclamptic placentas terminal villi and these changes were much prominent in sPE. We also detected insignificantly increased endothelial VEGF expression levels in preeclamptic placentas terminal villi. VEGFR-1 syncitial expression levels in sPE terminal villi were significantly higher in compare to the mPE and control groups. VEGFR-2 endothelial and syncitial expression levels were significantly lower in both PE groups terminal villi and these changes were much prominent in mPE. Patterns of VEGFR-3 expression in preeclamptic and control groups were multidirectional. Conclusion: Revealed patterns of VEGF and its receptors expression point on altered placental angiogenesis in PE and reflect different degree of such alteration in mild and severe PE. Objective: Chorionic villi vascularity disturbances, caused by abnormal expression of angiogenic factors could correlate with maternal and fetal complications in diabetic pregnancies. Method: Aim: to evaluate the patterns of VEGF receptors (VEGFR1, VEGFR2 and VEGFR3) expression in placentas from gestational diabetes (GD) and type 1 diabetes (D1) pregnancies and correlation between them and some clinical parameters in newborn (placental weight (PW), newborn weight (NW), placental/newborn weight index (PNWI),1st day of life blood glucose test results (1BGTR)). 29 term placentas from D1 (n=16) and GD (n=20) and 12 term placentas from normal pregnancy (control group) were studied. Results: In both D1 and GD group we revealed significantly higher level of VEGFR1 (p=0.0001), VEGFR2 (p=0.001) and VEGFR3 (p=0.01) endothelial expression in terminal villi. Difference in VEGFR1 expression among D1 and GD groups was also significant (p=0.0009) as difference in its expression between D1 and control group (p = 0.002). Among clinical parameters we only revealed significant increase in 1BGTR in diabetic groups (p = 0.03) with marked difference between D1 and control group (p = 0.002). We revealed multidirectional correlation between VEGF and VEGFR2 expression and NW in D1 and GD groups.