Quantitation of how often a disease phenotype was positively associated with a gene was performed as follows. GAD records having both recorded positive associations and annotated MeSH disease keywords were extracted and stored in a database according to their relationships. Using a perl script, the number of times of co-occurrence of a MeSH disease keyword was positively associated with a specific gene was recorded as found in the GAD database. These counts were sorted in declining order for each unique gene grouped by the disease MeSH term with which they are associated.