Supplemental data include three figure and three tables. carried out on 100 lipids. For each condition and time point, the following information is provided: Treatment P; p-values from the Anova analysis on minimum observations data (p,0.1), Exact mass; mass of each lipid from http://www.lipidmaps.org, [M+H] + ; Protonated molecular ion, NET; normalized elution time, total carbon/double bond; corresponds to each lipid species detected, LM_ID; identification for each lipid as displayed in LIPID MAPS, Formula, elemental composition of each lipid, PPM Error; difference in experimental mass compared to exact mass, Fold DENV/Mock; fold change of average abundance from 4 replicates of each treatment. Identity abbreviations were made for phoshatidylcholine (PC; O-fatty acid chain number means that an alkyl acyl linkage to the glycerol chain is present for the respective PC), phosphatidylethnolamine (PE), phosphatidylserine (PS), sphingomyelin (SM), ceramide (Cer), ceramide phosphoethanolamine (Cer-PE), lysophosphatidylcholine (LPC). The notation further indicates total number of carbons and double bonds however it does not discern redundancy associated with varying fatty acid composition for the same molecular weight. Accession numbers (LM_ID) were obtained from the Lipid Maps Gateway (lipidmaps.org). (PDF)