HBcIgM-hepatitis B core IgM antibody AHB-acute hepatitis B,CHBF-chronic hepatitis B flare ALT-alanine transaminase,PT-prothrombin time PE117 Detection of Emerging Drug Resistance Mutations Associated with Major Approved HBV Antivirals Using a Novel Line Probe Assay (LiPA). J. Doutreloigne 1 , F. Shapiro 1 , R. Maertens 1 , E. Van Assche 1 , E. Sablon 1 1 Hepatitis Diagnostics Unit, Innogenetics NV, Belgium Background: In study ETV-022, ETV demonstrated superior virologic, histologic and biochemical benefit compared to lamivudine (LVD). This study (ETV-022/-901) presents efficacy and safety results for patients who received 5 years continuous ETV treatment.