Botulinum toxin is produced by the obligatory anaerobic, gram-positive spore-forming soil bacterium Clostridium botulinum, and some strains of C. baratii and C. butyricum. There are 7 types of botulinum toxin (A-G), all of which use the same mechanism of action and can cause botulism. The toxin subtype is A in 50%, the remainder is usually B or E [79] . Types A, B, E, and F cause human disease, primarily affecting the nervous system [80] , and thus are of importance to neurologists.