There is pathological difference between adult coronary artery disease (CAD) and that caused by Kawasaki disease. CAD caused by Kawasaki disease is characterized by vascular intimal thickening, whereas the adult CAD is characteri-zed by atherosclerotic lesions initiated by atheroma and plaque formation. Thus, the pathophysiologic mechanism of myocardial ischemic development is also different; in adult CAD, plaque rupture and thrombus formation plays the important role, whereas in Kawasaki disease, coronary arterial narrowing by intimal hyperplasia is responsible (24) .