An alternative is the use of monoclonal antibodies [3] . Mouse monoclonal antibodies such as OKT3 have been used to treat humans but with limited success due to the immune response these antibodies provoked. An alterative approach could be the use of fully human antibodies. For this, novel technologies have been developed, including humanization of mouse antibodies, phage display of human B cell libraries, single cell PCR technologies and the creation of mice that express human immunoglobulin genes [4, 5, 6, 7, 8, 9] .