In addition to the suggestive clinical diagnosis, all patients had the Dengue virus infection confirmed either by antidengue enzyme-linked immunoabsorbent assay (ELISA)-IgM, serotype specific reverse transcription-polymerase chain reaction (RT-PCR) or by virus isolation [20] [21] [22] . Dengue immune response was considered as primary or secondary by IgG ELISA according to previously established criteria [23] .