The 19 confirmed dox-repressed genes that enhanced BMV RNA accumulation encode proteins with functions in varied cellular processes, including ribosome biosynthesis (DHR2, ECM16, NOP7, PWP1, RIO2, RPA43, UTP4, UTP18, and YGR251w), cell cycle/ DNA maintenance (ADE13 and SPC29), mRNA metabolism (RNA15, SPT6, and SWD2), protein homeostasis (PFY1), translation (DED1), trafficking (NUP57) and lipid synthesis (ALG14) ( Table 4 ). Possible relations of these functions to viral replication are considered further in the Discussion.