In the Lazio region, the measles elimination plan succeeded in increasing coverage for the first dose of MMR among children at two years of age from 83.9% in 2003 to 90.7% in 2007 [10] . During the same five year period, coverage among school-aged children (6-13 years of age) increased from 53% to 67% while coverage for the second dose at 15 years of age increased from 14% to 42%. In 2004 and 2005 a historically low incidence of < 1 case per 100,000 was reached in the Lazio region, with approximately 50 measles cases reported per year. However, sporadic cases continued to be reported, especially among susceptible adolescent and adults. Pockets of low coverage were also present in specific areas and among emarginated and hard-to-reach populations (HRP), such as the Roma/Sinti population, and illegal immigrants [11] .