i.5) CAS should be studied as a whole in addition to studying its constituents. Hence in vivo experiments are crucial to understand them. i.6) CAS are difficult to control for the following reasons: They are nonlinear. They are open. Delay is a generic property of CAS. Some failure cases in controlling CAS are the Measles-Mumps Rubella (MMR) vaccination and the change of fish type in Lake Victoria [2] . Therefore in the next sections we try to learn from some CAS systems to derive some principles for "managing" CAS.