Objective: Primary liver schwannoma (PLS) is extremely rare. Results: Case Report: A 69-year-old female with previous history of cholecystectomy, appendectomy, arterial hypertension and diabetes mellitus was admitted due to an intrahepatic nodular lesion identified in routine ultrasound examination. She was submitted to partial hepatectomy with postoperative uneventful evolution. Macroscopically, the specimen disclosed a 2.1 cm nodular, well circumscribed, yellowish tumour. Histologically, the tumour displayed an expansive growth pattern, comprising short bundles of spindle cells with mild atypia, without mitotic figures or necrosis. Immunohistochemically, the tumor cells expressed diffusely vimentin, S-100 and GFAP, in the absence of AE1/AE3, CAM5.2, CD117, and HMB45; Ki-67 index was 2 %. Staging procedures did not disclose evidence of any other tumor. There was no personal or family evidence of neurofibromatosis. These features are consistent with sporadic PLS.