Some discrepancies exist between our heritability estimates and previous results for humoral-mediated adaptive ITs and some innate ITs. Indeed, in our study, B lymphocyte levels (IgM + cells) are not significantly heritable contrary to other results [16, 17] and specific IgGs (IgG-Mh) have lower heritability estimates (0.12, se = 0.19) than previously reported (range from 0.27 to 0.45) for specific antibodies directed against other antigens [12] . Our estimated heritability for total IgG is higher (0.92, se = 0.20) than in published reports [3, 15, 18, 19] . In addition, our estimated h 2 for IFNa production is moderate to high (0.60, se = 0.23), contrary to previous results (range from 0 to 0.08) [15] , and for haptoglobin (0.55, se = 0.21) is higher than previously published (range from 0.14 to 0.23) [17, 19] . These discrepancies could be due to differences in the pig breeds and in environment factors but also to the absence of common standardised protocols between laboratories. In order to better qualify the phenotypes, protocol standardisation is needed.