All patients admitted to the ICU were close monitored and had treatment support according to the dysfunctions presented, namely transfusions of packed red cells whenever haemoglobin was lower than 7.5 g/ dL, associated with platelets and fresh frozen plasma in patients with bleeding disorders; blood products were also given before an invasive technique whenever platelets were lower than 50 × 10 5 /uL or if coagulopathy was present. Fluids were administered to correct hypovolaemia monitored by central venous pressure, mean arterial pressure and urinary output. Even so, 29 (49.1%) patients needed vasopressor support, with noradrenaline or dopamine or both. Ventilatory support was needed in 22 (37.3%) patients, for a period varying from two to 74 days (median 10 days). Two patients with severe ARDS with refractory hypoxaemia had been put on venovenous Extracorporeal Membrane Oxygenation (ECMO). In one of the patients, ECMO was completely successful and the patient is now doing well, without significant respiratory sequels; the other patient died on ICU in refractory shock. Eight (13.6%) patients required renal replacement therapy. Six patients had upper gastrointestinal bleeding and did an endoscopy for further study. All patients began enteric nutrition in the first 48 hours, if not contraindicated. Glycaemia control was monitored, being hypoglycaemia registered and treated in 18 patients (30.5%).