Method: We examined PANS structures obtained at post mortem from 28 subjects (19 female, age range 69-93, mean 81) at our Brain Bank with a diagnosis of PD (10); Lewy body dementia (5); Alzheimer's disease (9); mixed dementia or other (4). A complete neuropathological study of PANS was performed, including dorsal spinal ganglia, vagus nerve, paraspinal sympathetic ganglia, mesentery, adrenals, digestive and genitourinary systems, heart, and skin. Routine and immune stains for AS and tyrosine-hydroxylase were applied. Cases were semiquantitatively assessed.