After determining the symptom measures to be used in calculating each model of the URI symptom score, ROC analysis was done to determine the optimal cut-off value. Based on this cut-off value, the sensitivity, specificity, positive predictive value (PPV), negative predictive value, and accuracy of the model in predicting a viral URI were calculated; 95% confidence interval (CI) around the point estimates were also calculated. The sensitivity of the final URI symptom score in predicting the presence of viral URIs caused by rhinoviruses (versus no URI) was determined. A similar analysis was conducted for viral URIs caused by viruses other than rhinovirus.