to write a protein sequence with 10 amino acids. If we know the sequence is MMMMMMMMMM, we need information I=0 to write the sequence because it is already known. If we know the sequence is a DNA sequence, then the entropy of unknown is H = 10 log (4), so we need information I = ⋅ = 10 4 20 log( ) bits to write the sequence. If we know it is an English sequence but we do not know any English except 26 letters, then the entropy of unknown is H=10 log (26) . We need information