Acquired HLH, also known as secondary HLH, occurs more commonly in adults. Nonetheless, it is also described in children. There are presently no identifiable genetic mutations linked to this phenotype. Currently, secondary HLH is attributed to an abnormal immune response triggered by an infectious, oncologic or autoimmune etiology. As such, other names for secondary HLH include Virus-Associated Hemophagocytic Syndrome and Malignancy-Associated Hemophagocytic Syndrome [3] .