Adamantanes (amantadine and rimantadine) have no activity against the 2009 influenza A H1N1v pandemic strain. They are effective for seasonal H1N1 influenza strains, which are 100% resistant to oseltamivir. Therefore, for patients presenting with primary influenza pneumonia in geographic regions where seasonal H1N1 strains are circulating in addition to the novel H1N1 pandemic strain, amantadine or Computed tomography scan of the patient with primary H1N1 (swineorigin influenza A) influenza pneumonia whose chest x-rays appear in Figure 1 . rimantadine should be added to oseltamivir [46] . Rimantadine is also associated with immunomodulatory effects.