The strains of HRV-C species identified in the present study were characterized by analyzing the 59UTR, VP4, and part of VP2 (Fig. 3) . This approach showed the advantages of covering only 59NCR, VP4/VP2, VP1 or 3D genome fragments. Analyzing sequences that covered the 59UTR and the downstream VP4/ VP2 capsid region allowed identification of co-infections when several clones were sequenced, and helped to locate the recombination sites in strains of the HRV-Ca subspecies. Thus, this region of the genome may be useful for building a database of the novel strains that are circulating worldwide.