We detected 2 HBoV genotypes circulating at the same time in both symptomatic and asymptomatic children during the winter of 2002-2003 in Quebec. This result is consistent with fi ndings of other groups from North America and Europe during 2002-2004 and highlights the fact that HBoV lineages do not appear to be geographically clustered (1, 6, 9, 12) . The seasonality of HBoV infection is still a matter of debate, but it seems to involve primarily the colder months of the year (9, 20, 21) . However, most studies, including ours, were performed during the typical respiratory virus season, which may have introduced a bias. Additional studies are needed to address the prevalence of HBoV outside the respiratory virus season and its role in nonrespiratory syndromes. Moreover, the possibility that this virus might be transmitted and isolated in the respiratory tract, but could cause viremia and other clinical syndromes such as gastroenteritis, should be investigated. Vicente et al. analyzed 527 stool samples from children with gastroenteritis and no respiratory symptoms and found a positivity rate of 9.1% for HBoV (with a co-infection rate of 58%) (22) .