Treatment regimens according to the Working Group on Civilian Biodefense [48] are streptomycin (1 g intramuscularly twice a day×10 days) or gentamicin (5 mg/kg intravenously or intramuscularly every day×10 days) for isolated cases, and ciprofloxacin (500 mg by mouth twice a day×10 days), or doxycycline (100 mg by mouth twice a day×10-14 days) in the setting of a mass casualty. Postexposure prophylaxis is with ciprofloxacin or doxycycline for 2 weeks.