In the first presentation, by Espada et al, a behavioral program implemented by experts and peers is evaluated. Griffin will present a proposal for joint intervention on substance abuse and HIV transmission. Orgiles et al. address HIV prevention with young people under the stressor of the divorce of their parents. Huedo-Medina will show a meta-analytic review of the effectiveness of prevention programs with adolescents. It thus seeks to answer outstanding questions about HIV prevention with adolescents, the degree of the overall effectiveness of behavioral programs, the better alternatives to applicators, the relationship between HIV prevention and other risk behaviors, and intervention with high risk populations served shortly.