The intervention calculated in the previous section represents a gold-standard for this particular scenario because the vaccination strategy was calculated using the same parameter values and the same SIR model formulation as the simulated disease process. In most settings it will be natural to regard the transmission model parameters as unknowns to be estimated from incoming count data describing the sizes of the susceptible, infected, and recovered subpopulations. In this section we describe the procedure for performing adaptive management of an emerging epidemic, in which we account for parameter uncertainty and its impact on vaccination strategies.