X-ray and computed tomography (CT) scans of patient with severe Plasmodium vivax malaria Due to the severe condition of the patient, a five-day treatment was initiated, starting with an intravenous loading dose of quinine (1,200 mg) on the first day, followed by oral quinine (600 mg) every 8 hours plus oral doxycycline (100 mg) every 12 hours. The treatment was well-tolerated and parasitaemia became negative within three days. Platelet, erythrocyte and leukocyte levels were all within normal ranges in the following controls. Normal blood levels of glucose-6-phosphate dehydrogenase activity were detected and oral primaquine (30 mg/day) was commenced for two weeks to prevent a relapse. The patient recovered well and the chest CT findings were normal at two months ( Figure 1C ). There have been no recurrences during the follow-up period.