Diffraction data of a selenomethionyl derivative of the GNE kinase domain were collected at beamline 19ID of the Advanced Photon Source (APS) at a wavelength of 0.9792 Å . Initial phases were obtained by single wavelength anomalous diffraction with SOLVE and density modification with RESOLVE [25] . For model building, the phases were combined with data collected at APS beamline 23ID-B at a wavelength of 0.9793 Å (see Table 2 ). The refined model of the target resulted from iterative application of density modification with DM and RESOLVE, interactive model building with COOT [26] , coordinate and B-factor refinement with REFMAC [27] and PHENIX [28] , and geometry validation with MOLPROBITY [29] . Diffraction data and refinement statistics are summarized in Table 2 . The current model was deposited at the Protein Data Bank with PDB ID 3EO3.