The current international strain of novel H1N1 virus discovered in Mexico is derived from two unrelated swine viruses, one associated with a fourth generation of the 1918 human infl uenza virus with which acts to recombine the viruses and its progeny [4, 18] . Essentially the virus continues by shuffl ing its eight genes in the avian reservoir to eventually be passed to swine and other mammals before the encounter with humans. Seldom are there transfer of infl uenza between humans and avian. Pigs act as the "transformers or converters" for the various infl uenza viruses and let loose the world new "strains" of the infl uenza virus. The intervening passage continues to be through the domesticated pig, as they have the mechanism to convert the arrangement of the sialic acids to become receptive to human cells [21, 22] . The arrangement of the genes, determine the protein sheath structure and the interaction between the antibody defenses of the host. A mere change of one amino acid can change the impact of the infection, from a mild discomfort to a killer virus [14] . One of the major concerns of the 2009 H1N1 is this very issue; will it change between the waves of outbreaks?