LGTV TP21-induced structures in acutely infected ISE6 cells. Animation through a z-series and 3D surface rendering of a semi-thick section of an acutely infected ISE6 cell. ER is depicted in green and vesicles & tubules in blue. Vesicles and tubules are contained within proliferated ER. Tubules are short in length, only reaching approximately twice the diameter length. The images were aligned using Inspect3D software (FEI, Inc.) and rendered using Amira (Visage Imaging, Inc., San Diego, CA).