Although FCGR polymorphisms have been demonstrated to be associated with susceptibility and severity of numerous infections, there has only been one previous genetic association study on the relationship of FCGR genotypes and cryptococcosis [18] . Meletiadis and colleagues genotyped FCGR2A 131H/R, FCGR3A 158F/V and FCGR3B NA1/NA2 in 103 cryptococcosis patients and 395 healthy controls. They found that in patients with cryptococcosis FCGR2A 131R/R and FCGR3A 158V/V were over-presented (Pvalues were 0.04 and 0.04), while FCGR3B NA2/NA2 was underpresented (P-value was 0.04).