The Triple-S project coordinated by the French Institute for Public Health Surveillance (InVS) is divided into six work packages (WP). Three are horizontal managerial WP for coordination, dissemination and evaluation. The other three concern an inventory of existing systems (WP4), country visits (WP5) for knowledge exchange and a deeper understanding of a selected number of systems. WP4 and 5 will lead to the development of guidelines for implementing syndromic surveillance in Europe (WP6).