Based on the most reliable documented cases of exposure and subsequent illness, MVD has an incubation period ranging from 3 to 21 days (typically 5 to 10 days), which is likely modulated by factors such as infectious dose and possibly by route of infection. The course of MVD has conventionally been broken down into three phases [45] : an initial generalization phase, an early organ phase, and either a late organ phase or convalescence phase depending upon disease outcome [45] . A summary of MVD symptoms is reviewed below [16, [46] [47] [48] [49] .