OFP-07-008 Still's Disease associated lymphadenopathy: Report of two cases resembling malignant lymphoma with review of possible morphological findings K. Kamarádová * , M. Nova, M. Kalinova, V. Campr * Prague, Czech Republic Objective: Still's disease (or systemic onset juvenile idiopathic arthritis, SOJIA) is a systemic inflammatory disorder characterized by fever, rash, and arthritis. It has a peak of incidence in early childhood with rare occurence in adulthood (adult-onset Still's disease, AODS). Several other symptoms as hepatosplenomegaly, leukocytosis and lymphadenopathy may be associated possibly mimicking malignant lymphoma. Method: We present two cases of Still's disease associated lymphadenopathy in a child and in an adult simulating morphologically peripheral T-cell lymphoma and classical Hodgkin lymphoma respectively. Results: Histological, immunohistochemical and molecular examination revealed non-neoplastic lymphadenopathy with atypical paracortical T-cell hyperplasia with immunoblastic reaction in the former and burnt-out histiocytic pattern in the latter, both falling into a broad spectrum of reactive lymph node changes associated with Still's disease.