We aligned the GP1 sequences of MACV (residues 59-258) with those of JUNV, GTOV, and SABV to identify conserved residues mapping to the surface of the determined MACV GP1 crystal structure (DNAStar Lasergene Software). We identified ten residues of interest that did not contact hTfR1 in the co-crystal structure yet are conserved in at least three of these viruses: D140, W147, D155, D159, P160, K167, N178, and K211 (colored red, Fig. 1 ).