This study identified MELD score above 23 as an independent risk factor of morbidity represented by ICU stay longer than 10 days but it did not clearly affect mortality. This finding supports the transplantation of patients with high MELD score at the cost of increased postoperative morbidity, in particular when it is seen in the light of reduced waiting list mortality. Furthermore, we identified transfusion of more than seven units of RBCs as an independent risk factor for mortality and for prolonged ICU stay. Postoperative renal failure and transfusion of more than 10 units of FFP are strong predictors of morbidity and postoperative RRT was highly associated with increased mortality, as was hepatorenal syndrome prior to transplantation.