The number of published differentially expressed genes during epileptogenesis is fast approaching 2000. On review of the available data from these publications there is minimal conformity between the genes described. Lukasiuk et al has produced a list of common differentially expressed genes involving models of epileptogenesis, including traumatic brain injury studies (62) . From the near 2000 genes, only a small number (53) are noted to be differentially expressed in more than one study. However, if the gene profiles of traumatic brain injury studies are filtered out, only 38 genes remain differentially expressed across studies. In addition, a proportion of these common genes appear to be differentially expressed in conflicting directions.