The premise behind this MREP is taken from the AnyBody Web site [13] . The site describes how the cost of musculo-skeletal injuries is rapidly increasing, while fundamental understanding of the mechanical functions of the body is increasing at a dramatic rate. However, it notes that there are still many unknown questions and problems researchers are addressing. For example, the AnyBody Web site indicates that the number of ergonomic-based injuries caused by excessive use of the computer mouse is exploding, yet the actual cause of many of these injuries remains a mystery. Policymakers and others, therefore, find it difficult to issue guidelines to reduce the problems. Also, research into human locomotion has historically been relegated to experimental studies (for detail, see http://anybody.auc. dk/).