Method: Immunohistochemical staining was used to detect PDGFR expression in archived formalin-fixed, paraffin-embedded Schwannoma tissue samples (n=24 Objective: Pancreatic ductal carcinoma (PDC) has one of the worst prognoses. Up to 90 % of pancreatic cancers are diagnosed at the locally advanced or metastatic stage. However, brain metastases from pancreatic carcinoma are extremely rare since less than 20 cases have been reported in the literature since 1978.