The government of Rwanda, through collaboration with its partners, has begun to strengthen the organizational capacity of the public health laboratory network for identification and confirmation of priority diseases. The laboratory network has a hierarchal structure with the central referral laboratories as lead authorities and the health centre-based laboratories at the periphery. Other referral hospitals laboratories also link to the National Reference Laboratory. There is a defined role for each level with level-specific standard operating procedures. The NRL is the focal point for national public health laboratory leadership and coordination of partners to establish and expand the laboratory network. Reporting on specimens processed from the district and hospital laboratories is integrated and submitted along with the weekly disease reports for selected priority diseases. Supervision and feedback is done using a check list as applicable to the different levels.