Results: Kaposi's sarcoma represented 21 % of soft tissue sarcomas. There were 23 (32.4 %) females and 48 (67.6 %) males (male-to-female ratio: 2.1:1). Median age at diagnosis was 69 (range: 10-98 years). The age distribution showed that elderly (≥60 years) were the most affected patients with a frequency of 66.2 %, followed by patients aged 31-59 years (25.3 %), and patients under 30 years (8.4 %). The most common location was the lower limbs, particularly the distal lower extremity (73.3 %), followed by contiguous location (7 %), and soft tissue, NOS (7 %). Conclusion: Kaposi's sarcomas were more frequently diagnosed in elderly. The distal lower extremities were more involved. Objective: Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. In this study, we analysed the epidemiological pattern and antomoclinical features of rhabdomyosarcoma in Central Tunisia. Method: We retrospectively studied all cases of rhabdomyosarcoma diagnosed in the Pathology Department, Farhet Hached Hospital, Sousse during a 15-year period. Results: There were 15 (31.9 %) females and 32 (68.1 %) males (male-to-female ratio: 2.1:1). Median age at diagnosis was 9 (range: 0-85 years). Rhabdomyosarcoma was more frequently diagnosed in childhood (63 %) than in adults (37 %). In children, the tumour size was higher than 5 cm in 73 % of cases, the embryonal subtype was the most frequent (60 %) and the two most common sites of disease were the head and neck (50 %) and genito-urinary tract (23.3 %). In adults, the tumour size was higher than 5 cm in 90 % of cases, the pleomorphic subtype was the most diagnosed (41 %), and limbs were the most involved sites (41 %). Conclusion: Rhabdomyosarcomas is more frequently diagnosed in children than in adult. Head and neck locations were the most involved and embryologic type was the most diagnosed. In adults, rhabdomyosarcomas were more frequently localized in limbs and diagnosed as pleomorphic type.