NT-proBNP. NT-proBNP level is used for screening and diagnosis of acute HF and may be useful to establish prognosis in HF, as it is typically higher in patients with worse outcome [109] . It was reported in 12 studies [20, 22, 38, 45, 49, 52, [54] [55] [56] [57] [58] [59] Heart Rate and Blood Pressure. Heart rate and blood pressure were reported in 27 and 15 trials, respectively. Metaanalysis showed that there was statistical significance between SFI group and control group (WMD: 6.31; 95% CI [5.18, 7.44] , P < 0.01) (see Supplementary Figure 1 Results of Ultrasonic Cardiography. LVEF is the ratio of the stroke volume and the left ventricular end-diastolic volume [107] . It is usually used for the assessment of HF and drug efficacy. Sixty-one studies reported the outcomes for LVEF. Meta-analysis showed that SFI group was better than control group in increasing LVEF (WMD: 6.31; 95% CI [5.18, 7.44] , Figure 4) .