HBoV was the only virus identified in 6 children and was associated with respiratory syncytial virus in 3 other children. An infection with other respiratory viruses was detected among 153 (60.5%) of the 253 HBoV-negative children. The viruses identified were respiratory syncytial virus in 114 (43.5%) samples, human metapneumovirus in 27 (10.3%) samples, influenza A virus in 14 (5.4%) samples, rhinovirus in 4 (1.5%) samples, adenovirus in 2 (0.8%) samples, and parainfluenza virus type 3 in 1 (0.4%) sample. Respiratory syncytial virus was associated with human metapneumovirus in 9 (3.4%) samples.