The idea of immunizing the pregnant animal with the intent of controlling neonatal morbidity and mortality is well established [38] . Vaccination or natural immunization of the pregnant cow, ewe or sow against enterotoxigenic Escherichia coli [38] [39] [40] or intestinal viruses [41, 42] , can provide a degree of protection for the newborn. As an example, while only limited protection against viral challenge occurred in calves fed once shortly after birth with a pooled colostrum from cows immunized against bovine rotavirus, a shorter duration of diarrhea was observed [43] . On the other hand, calves fed milk supplements with low levels of a similar immune colostrum at each feeding for two weeks did have reduced virus sheading and reduced incidence of diarrhea [44] .