Objective: Pleomorphic adenoma (PA) is the most common tumor of salivary glands and, despite its benign behavior, the recurrence after primary surgery is significant. In attempt to find a marker capable to predict the recurrence of this lesion, this study aims to analyze the expression of mucins MUC 1, 2, 4, 5 AC and 6 in 62 cases of PA, considering that mucins have been related to tumour growth of some organs.