The epidemic of HEV in Kitgum lasted a period of over two years [7] . Within this period, 160 individuals have lost their lives. As a result, the disease burden, the functional limitation and premature mortality have equaled a disability adjusted life years equal to 7,066, even allowing for the relatively low life expectancy in this part of Uganda. This paper provides a case study of how a simple epidemic model can be fit to such an outbreak disease. Two fitting methods have been used; the first, an analytical method and the other based on a freely available fitting tool. Using these methods, a reliable estimate of R 0 &2:2 has been provided.