None of the Roma/Sinti cases were vaccinated against measles, and only 16 (5.5%) cases from the Italian ethnic population had received one dose of measles-containing vaccine. Overall, over 57% (258/449) of cases required hospital admission. Fifteen cases (3.3%), 12 of whom from the first outbreak and three from the second, reported a hospital contact with children affected by measles, either in the waiting area or after admission for a different condition. Four of these contacts were healthcare professionals (two nurses and two physicians). Out of the 15 reported cases of nosocomial transmission, seven involved contacts with Roma/Sinti children, including the first two cases in the Italian ethnic population.