Microfluidic chips have been applied to the detection of LAMP reactions in recent years. Some chips are used only for guiding the reaction buffer and DNA solution to the reaction chamber, whereas others are combined with additional technologies such as nanostructures for sample concentrating, electrophoresis, magnetics beads, etc. A microfluidics chip made of PMMA has been used for the turbidity detection of the hepatitis B virus (HBV) LAMP reaction by our group [67, 68] . With a disposable LAMP microreactor and optical fiber-based turbidimetry device, as shown in Figure 4 , the lowest limitation for detection of the HBV DNA template was 50 copies/25 μL with the critical detecting time set at 30 min. 