TREM-1 has been studied in patients with pneumonia, especially VAP [5, 21, [36] [37] [38] . Few data are available on the diagnostic role of TREM-1 and of sTREM-1 in patients with lung infiltrates. Our data are in agreement with observations from the study by Phua [36] . Their proposed sTREM-1 cut-off point was 163 ng/ml, which is different than the one we found. This may be result from the different method of assaying sTREM-1 the used being Western blotting.