A previous study by Meletiadis et al. investigated FCGR polymorphisms in patients with cryptococcosis, and found that FCGR2A 131R/R and FCGR3A 158V/V were over-presented, and FCGR3B NA2/NA2 was under-presented in patients with cryptococcosis [18] . The purpose of this study was to investigate FCGR polymorphisms in our series of patients to further verify the association between FCGR and cryptococcal meningitis.