In two of them, an acute disseminated encephalomyelitis (ADEM) was diagnosed based on neurologic dysfunction and cerebral resonance magnetic image; both had a favourable outcome. All patients were also evaluated after hospital discharge for follow-up of residual dysfunctions and no other sequelae were detected; in those whose rapid malaria test had been consistent with coinfection with P vivax, primaquine was prescribed after excluding Glucose-6-Phosphate Dehydrogenase deficiency.