Becker et al correlated temporal changes of genes associated with cellular stress and injury at 3-day post-status epilepticus, genes associated with cytoskeletal and synaptic reorganization at 14-day post-status epilepticus, and genes involved in neurotransmission pathways at the chronic epilepsy stage. This study also provided the first comparison with human hippocampal specimens with eighteen genes differentially expressed in both the chronic stage of pilocarpine induced epilepsy and medically refractory MTLE (4) .