Though epitope mapping based on phage display can be done manually [11] , it is quite tedious and time-consuming to compare a set of mimotopes to the antigen without computational support. The low sequence similarity between the mimotope and the antigen often makes the mapping even harder. To solve these problems, several groups have researched algorithms and programs that assist and automate phage display based epitope mapping [12] [13] [14] [15] [16] [17] . According to their dependency on antigen structure, the existing programs for phage display based epitope mapping can be classified into three categories. Program in the first category such as FINDMAP, only work with sequence data from the mimotopes and antigen [13] . The second category needs both the sequence data and the antigen structure. SiteLight [12] , 3DEX [14] , and Mapitope [16, 17] belong to this category. A very recently published work: MIMOP [15] makes the third category, which integrates the two different approaches and can work with or without the antigen structure. Though implemented differently, all the existing programs have succeeded in given cases. However, most of the existing tools have not been implemented as a freely available online service until now, making it less convenient for the community to access, utilize, and evaluate them.