Results: Upper GI endoscopic examination revealed a pedanculated polyp, in the greater curvature. Endoscopic ultrasonography revealed a polypoid heteroechoic mass with cystic area and 20×22 mm diameter in posterior wall of gastric body. Polypectomy was performed without any complications. Histological examination of the protruding lesion revealed some misplaced cystic glands were entrapped in dense disorganized bundles of smooth muscle of muscularis mucosa surrounded by a rim of lamina propria. These findings were consistent with gastritis cystic polyposa. Objective: Human papillomavirus (HPV) infection is a known risk factor for the development of squamous cell carcinoma (SCC) of the cervix, the oropharynx and the anogenital region. The aim of our investigation was to assess the prevalence of HPV DNA in patients with esophagus cancer in the Western population. Method: Formalin-fixed paraffin-embedded blocks from 37 consecutive patients who underwent esophageal endoscopic mucosal resection or esophagectomy for SCC were tested for the presence of HPV DNA by polymerase chain reaction using consensus primers GP5+/GP6+. Viral genotyping was determined by type-specific primers.