The Acanthamoeba polyphaga Mimivirus and the family Phycodnaviridae [24] , contain many genes that are found in cellular organisms. For example, the giant virus Cafeteria roenbergensis virus (CroV) includes numerous eukaryotic-like genes for translation factors, ubiquitin pathway components, intein elements, histone acetyltransferase and more [25] . These are extremely large viruses of aqueous environments that infect bacteria, animals and protists [26] .