Currently, SFI used alone or integrated with routine treatments has been widely accepted as an effective method for the treatment of HF in China. Many clinical studies reported the effectiveness ranging from case reports and case series to controlled observational studies and randomized clinical trials, but the evidence for its effect is not clear. This paper aims to evaluate the beneficial and harmful effects of SFI for treatment of HF in randomized controlled trials. (Shenfu injection or Shenfu or Shen-fu) AND (heart failure or cardiac dysfunction or cardiac inadequacy or cardiac failure or congestive heart failure). All of those searches ended before November 2011. And the bibliographies of included trials were searched for thorough references, irrespective of languages.