Examination of the predictors of intention to self-examination showed that higher body image and educational level had a positive impact on confidence, although no direct relationship to intentions. In this study, we developed the Takeda Three Colors Combination Test (TTCC) as a simplified screening test for early detection of AD and examined its effectiveness. 166 senior persons participated in the research; 91 with mild AD and 75 healthy volunteers represented the control group. The TTCC, which is a colored cards configuration memory task, was examined for sensitivity and specificity as well as reliability and validity. The sensitivity of the TTCC in detecting mild AD was 84% with a specificity of 87%. The positive predictive value was 89%, the negative predictive value was 82% and the predictive accuracy was 86%. The odds ratio of the incorrect response to TTCC with control group as a standard was 32.0 (95%CI,13.1-78.1, p< 0.0001) for mild AD group. Including the results of the re-tests, the Phi coefficient indicated 0.76 (p<0.0001) and the consistency percentage between first and second trials was 88%. Spearman's rank correlation analysis, using MMSE as an external standard, revealed a significant correlation between MMSE and the TTCC results (ρ=0.58, p< 0.0001). Conducting the TTCC (including instruction and evaluation) was accomplished within 2 minutes for all subjects. No refusal or resistance to this test was observed among any of the subjects. The TTCC has proven to be of adequate sensitivity and specificity as a screening test for early detection of AD. Furthermore, administration time is short and requires no special training or skills. Thus, we believe the TTCC shows great potential for use as an AD screening test by a general practitioner in communities worldwide. Objective: To understand reasons that influence African-American participation in a study designed to increase CRC screening in primary care. Methods: As part of a larger randomized, controlled behavioral intervention, we administered a baseline telephone survey to 134 African-American primary care patients ages 50 to 79. The survey included sociodemographic background measures and perceptions about CRC and screening. We also asked consenting participants why they joined the study. The research team performed content analysis of responses to this question and tallied categories. Results: 75% of respondents were female and 25% male. Ages ranged from 50 to 79 with 72.4% of participants between ages 51-60. In this sample, 38% had a HS/GED education, 19% had a college degree or more, and 17% had a technical degree. Primary reasons for participation included: desire to support research (45%), contact by study staff (36%), and a desire to maintain health (34%).