Considering 2-D computation of b-scale scenes, one may doubt if the algorithm can be extended into 3-D. Based on our observations on appearance and location of TIB patterns over the lung regions and experiences on feature extraction in 3-D, as we stated previously, TIB patterns rarely extend in depth direction for more than a few slices due to constraints of lowresolution imaging direction. Therefore, there is no significant classification rate changes in 3-D; however, there is an increase in computational cost. Nevertheless, 3-D b-scale encoding and feature extraction for a similar pattern detection problem or the same problem with high-resolution images (with thinner slice thickness compared to low-resolution CT images) can readily be combined and used with similar accuracies reported in this study.