We performed a literature search in PubMed, MEDLINE, Embase, Wanfang Database and Weipu Database for studies published through April 2011 to use in this meta-analysis. The key terms were ''DC-SIGNR or CLEC4M or CD209L or L-SIGN or CD299 or DC-SIGN2'', ''HIV-1'', and ''polymorphism'' in various combinations. The search was limited to articles published in English and Chinese. We also manually searched the references matching the above criteria to identify additional studies.