Given the above caveats, it is important to emphasize that we do not advocate these results to be accurate quantitative reflections of resources shortages or deaths that are likely to occur in any given pandemic scenario. Rather, they highlight the scale of health system inequalities within and across countries in Asia, and the considerable impact such inequalities could have on the pandemic disease burden. By indicating the relative disparities in resource availability within and across countries, and the potential consequences of resource shortages, these results could help guide investment decisions in scaling up resources to mitigate the burden Figure 5 . Estimated impact of resource mobilization/redistribution across provinces on avoidable mortality rates within each territory. Data were calculated by estimating the number of avoidable deaths if available resources (including central stockpiles for oseltamivir) within each territory were geographically distributed in proportion to provincial population size, and comparing with the total number of avoidable deaths predicted given actual resource distribution. Boxplots show medians, interquartile ranges, and 95 th percentile ranges derived from a multivariate uncertainty analysis. Data are aggregated across provinces for Cambodia, Lao PDR, Thailand, Vietnam, and across counties for Taiwan. Data for Indonesia are aggregated across districts of Jakarta and Bali only. doi:10.1371/journal.pone.0031800.g005 of future pandemics. As many of these resources have a generic healthcare function beyond pandemic influenza, they may also be useful to guide health system strengthening. Figure S1 Variation in estimated resource capacities across provinces within each territory for the modeled pandemic scenario. (DOCX) Figure S2 Geographical distribution of estimated avoidable deaths due to resource gaps for a modeled pandemic influenza scenario.  Epidemiology and viral etiologies of Severe Acute Respiratory Infections (SARI) in the Northern Vietnam   Impact of different influenza cultivation conditions on HA N-Glycosylation  Jana V Roedig 1 Background Influenza virus is a highly contagious human and animal pathogen causing infections of the respiratory track. Prevention such as high standard hygiene and vaccination still represent the best measures for protection. Beside the traditional egg-based influenza vaccine production, numerous cell culture-based processes are currently being established. Due to its ability to induce strong and protective immune responses, the highly abundant glycoprotein hemagglutinin (HA) represents the major component in influenza vaccines. Since variations in Nglycosylation of glycoproteins such as HA can alter quality characteristics of antigens, the impact of cell lines and process parameters for vaccine manufacturing needs to be addressed. This study investigates the impact of virus adaptation and different harvest time points on HA N-glycosylation. Therefore, the HA of influenza A virus Uruguay/716/2007 (H3N2, high growth reassortant), in the following referred to as IVA-Uruguay, was purified and N-glycans analyzed by capillary gel electrophoresis with laser-induced fluorescence (CGE-LIF).