To date no approved treatment is available for MARV infection. Supportive care (fluids, anti-microbials, blood transfusions) has been the primary treatment of patients during MVD outbreaks. In the guinea pig model various treatments had some success as reflected by prolonged survival or increased survival rates. Applied treatments included cytokine inhibition, IFN treatment, or antibody transfer. The tested treatments were unsuccessful in the NHP model (reviewed in [16, 47] ).