Plant lectins extracted from Maackia amurensis (M. amurensis leukoagglutinin, MAL) and Sambucus nigra (S. nigra agglutinin, SNA) are usually applied for the detection of Neu5Aca2-3Gal (SAa2-3Gal) and SAa2-6Gal glycans in tissues, respectively [3] . Two types of M. amurensis lectins were discovered: one that can agglutinate erythrocytes (hemagglutinin) (MAH, also known as MAL-II) and one that can agglutinate leukocytes (MAL, also known as MAM, MAA, MAL-I). Although both MAL-I and MAL-II recognize the SAa2-3Gal glycan, previous studies [4] and recent glycan microarray data [5] demonstrated that subterminal sugars affect their binding affinity to these two lectins. For example, MAL-I, rather than MAL-II, showed the highest affinity to the SAa2-3Galb1-4GalNAc and did not bind to this oligosaccharide when the subterminal b1,4-linkage was replaced by a b1,3-linkage [6] .