Understanding the underlying factors behind the spread of diseases is one of the core objectives of infectious disease epidemiology. By reconstructing the transmission tree of an outbreak, our method creates new opportunities for testing how various features of the connectivity between hosts shape transmission patterns. For instance, despite limited genetic information available for the early stage of the swine-origin A/H1N1 influenza pandemic, we observed a positive association between flight traffic and the routes of transmissions inferred by SeqTrack, in line with previous works on both seasonal and pandemic influenza (Brownstein et al., 2006; Cooper et al., 2006; Ferguson et al., 2006; Germann et al., 2006; Viboud et al., 2006; Fraser et al., 2009) . The versatility of the presented methodology makes it applicable over a wide range of scales, from localized outbreaks of a nosocomial infection within a hospital to the global spread of a newly emerged pathogen. In not requiring extensive genetic polymorphism, the method should prove effective in bacteria and fungi, in addition to viruses. We hope that the performance of the method, together with its wide applicability, flexibility and computational speed will convince infectious disease epidemiologists to adopt it as an integral part of the toolkit for infectious disease outbreak analysis. Human Bocavirus – Insights into a Newly Identified Respiratory Virus Human Bocavirus (HBoV) was discovered in 2005 using a molecular virus screening technique. It is often found in respiratory samples and is a likely cause for respiratory diseases in children. HBoV is distributed worldwide and has been found not only in respiratory samples, but also in feces, urine and serum. HBoV infections are mostly found in young children and coinfections with other respiratory viruses are often found, exacerbating the efforts to link HBoV to specific symptoms. The purpose of this review is to give an overview of recent HBoV research, highlighting some recent findings. Human bocavirus (HBoV) was discovered in 2005 by Allander et al. [1] in respiratory samples from children with suspected acute respiratory tract infection (ARTI) using a novel technique. This molecular virus screening is based on a random PCR-cloning-sequencing approach and was employed on two chronologically distinct pools of nasopharyngal aspirates (NPAs). It revealed a parvovirus-like sequence, with close relation to the members of the bocavirus genus.