For the diagnosis of HAPE, criteria 1, 2 and 3 must be met. These findings, together with those in 4, 5, 6, 7, and/or 8, are then used to confirm HAPE. Using these criteria, the severity of disease can be determined, which is critical for individualized therapy. With early diagnosis and early treatment, HAPE can be controlled at the early stage and the symptoms be markedly improved.