ICAM-1 was highly expressed on HK-2 cells. ICAM-1 expression decreased with TGF-b 1 stimulation at concentrations of 10 .0 ng/ml, 1.0 ng/ml and 0.1 ng/ml after 24 hrs in a dosedependent manner ( Figure 1A ); its expression also showed a timedependent decrease at 24 hrs, 48 hrs and 72 hrs after TGF-b 1 (10.0 ng/ml) stimulation ( Figure 1B) . However, its expression was still maintained at a high level.