It must also be observed that matching between prediction and reality is slightly better for small proteins than for large proteins. For example, the probability pJ to find J values larger than those observed by comparing the reality and the predictions of the method "baker" is on average equal to 39%, it decreases to 33% for proteins shorter than 150 residues, and it increases to 43% for proteins containing more then 150 amino acids. This is actually not surprising, since it is easier to predict that a small protein contains a single domain, with, perhaps, two small N-and C-terminal segments protruding from the domain. However, it must be noted that, despite the fact that the pJ, pR, and pFM values can be used only as semi-quantitative indicators -since they are obtained from empirical statistical distributions -it is quite clear that the domain boundary predictions are still quite far from matching the reality.