To examine this we performed co-immunostaining of lung tissue for surfactant protein C (Pro SP-C) a marker for alveolar type II cells and VP1 viral capsid protein (Figure 5 ). The figure depicts co-localization of Pro SP-C and VP1. These findings support our conclusion that the vector is internalized into alveolar type II cells. The ability to transduce these cells is essential because of their impor- tance in alveolar epithelial repair processes and lung recovery in ARDS [10] .