Background/aim: Accumulation of oxidative damage to proteins, lipids and mitochondria could increase with advancing of age. The current study was aimed to test the hypothesis that swimming exercise training could revert the age dependent oxidative damages in liver. Methods: Sprague-Dawley rats of young (3 months) and old (12 months) were divided into four groups; young control (n=5), young exercise (n=5), old control (n=5) and old exercise (n=5). 90 minutes of swimming exercise was given to the exercise group for a period of two weeks. Results: The estimated antioxidant enzyme activities including, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and glutathione reductase (GR) were decreased with age and significantly (p<0.05) increased with exercise training. However, elevated protein carbonyls and MDA levels were noticed in old animals, which indicate that old liver had greater accumulated oxidative damages. The significant drop in protein carbonyl content and increase in mitochondrial succinate dehydrogenase (SDH) activity was observed with response to swim training in old rats. Conclusions: This data implied that swim exercise training could revert the oxidative damages in liver. This was also proven by enhanced antioxidant enzyme status with response to exercise training in old rats. To sum-up these results it is cleared that age induced detrimental effects to the liver might be reversed by regular swimming exercise training in old rats.