The targets associated with the health MDGs are to: (i) reduce child mortality by two-thirds between 1990 and 2015; (ii) reduce the maternal mortality ratio by three quarters between 1990 and 2015; (iii) halt and begin to reverse the spread of AIDS by 2015; and (iv) halt and begin to reverse the incidence of malaria and other major diseases by 2015. Developed countries and the development agencies will, in return for low-and middle-income countries' devoting effort to attaining the MDGs, take primary responsibility to establish a global partnership for development. In the area of health, the associated target is: (v) provide, in cooperation with pharmaceutical companies, access to affordable essential drugs in developing countries.