Morphological justfication of using pulsed electric discharge in surgical treatment of echinococcosis M. Tussupbekova * , D. Kaliyeva, E. Turgunov * Medical University Karaganda, Dept. of Pathological Anatomy, Kazakhstan Objective: Echinococcosis is characterized by lesions of internal organs, severe complications, often lead to disability and death. Method: New method of processing of the residual cavity with impulsive electric discharge after echinococcectomy was experimentally developed and introduced into clinical practice. The effectiveness of the method is confirmed by morphological examination of operational bioptic of the liver tissue. Results: 20 patients underwent surgical treatment with the new method (Patent of the Republic of Kazakhstan ¹ 63558). Parasitic cysts with an inner germinal layer and protoskoleks, outdoor layer -chitinous shell with a productive reaction with lymphocytes infiltration, single eosinophils, separate groups of hydatid bubbles with their invasion in the liver tissue were detected in the histological examination of material taken intraoperatively prior processing of residual cavity with electropulse discharge. Fibrinoid necrosis, destruction of germinal elements, single lymphoid infiltration, hyperemia of blood vessels, absence o inflammatory reaction were marked in the histological material after processing by impulsive electric discharge.