Lymphomas are a heterogenous group of malignant disease ranging from very aggressive clinical course like Burkitt lymphoma to indolent diseases which do not need to be treated. Histological diagnosis is crucial to define treatment and to target it (Rituximab is only given to B-cell lymphoma expressing CD20 antigen). Unless refractory or very early relapses, patients with recurrent disease should have a radiological non-invasive biopsy to detect histological modifications: a) histological transformation from low-to high-grade B-cell lymphoma, b) Hodgkin lymphoma recurring with non-Hodgkin lymphomas (NHL), c) loss of CD20 antigen expression in relapsing B-cell lymphoma and d) second solid tumour. Before treatment radiological evaluation must be planned with CT or PET-CT and criteria of response must be defined if PET-Ct is used as an interim response and not only at the end of treatment (Juweid JCO 2007). Physicians must define their therapeutic goals: a) complete remission leading to long-term cure, b) prolongation of survival and c) quality of life in elderly or incurable disease. Response with radiological evaluation may guide therapeutic options. 1. good responders: limit the treatment and avoid long-term toxicities (mostly for Hodgkin lymphoma), 2. slow responders: give the optimal amount of treatment and radiation therapy in some localised cases and 3. bad responders: increase the treatment and proceed to high-dose therapy. In conclusion, the management of lymphoma patients needs non-invasive biopsies and multiple (PET)-CT evaluation for optimal care. imaging findings with results from various prior radiologic studies and pertinent clinical information. The frequently numerous findings visible on an imaging study need to be distilled into a focused, clinically relevant report; otherwise, the radiologist functions simply as a "film reader" (rather than as a true consultant), and the resultant radiology report may be technically accurate but clinically unhelpful---or even misleading. Better reports can be produced by using standardised report templates, integrated imaging summaries and consistent lexicons. The most important parameter for the developing of the subgroups was overall survival based on disease stage. The major changes involve the T and M categories, resulting in subgroups that would more accurately be associated with prognosis of a patient with defined descriptors. In this course, the new TNM staging classification will be demonstrated, and case examples will be used to interactively enhance the learning experience of attendees. Also, the role of imaging methods in evaluating standard and innovative therapy regimen will be discussed, and typical findings and pitfalls will be presented. Over the past decade, the treatment of colorectal cancer has become increasingly individualised with therapeutic options ranging from neoadjuvant therapy with FOLFOX and radiation therapy, to transanal mucosal resection, to robotic surgery with low anterior resection and surgical extirpation including APR. This lecture reviews the role of CT, MR, transrectal ultrasound and PET-CT in guiding the increasingly sophisticated process of staging and managing patients with colorectal cancer. Guidelines concerning the most efficacious use of the DWI MR imaging and perfusion and diffusion CT and MR with a view towards optimising patient management are also presented. Over the past years, the number of coronary CTA studies performed has been steadily growing. To perform a coronary CTA study using appropriate protocols in a correct manner is mandatory in order to obtain a diagnostic image quality. Beyond that, there is a lot more to a coronary CTA study than acquiring the data. Correct interpretation required knowledge of the advantages and disadvantages of various post-processing methods in order to avoid false-positive and false-negative findings regarding coronary artery disease. In addition, a standardised approach for interpreting the CT data and for reporting the imaging findings to the referring clinician is reasonable. The presentation illustrates a practical approach to the post-processing and interpretation of data acquired during a coronary CTA study, including the reporting of the relevant imaging findings to the referring clinician. Learning Objectives: