Objective: Hepatic angiomyolipomas are rare mesenchymal hepatic tumour. The most important problem about their diagnosis on biopsy specimens is to exclude a hepatocellular carcinoma. Method: We present two cases of hepatic angiomyolipoma diagnosed in Fundeni Clinical Institute, Bucharest. Both females patients, 39 and 43 years old, were imagistically diagnosed with a 13 cm hepatic left lobe tumor in the first patient, respectively a 10.5 cm hepatic right lobe tumor in the second one. Both tumors were echo guided biopsied. The biopsy specimens measured about 8 mm, respectively 20 mm. The tumors were surgical removed. The biopsy and resection specimens were analyzed in light microscopy, including immunohistochemistry. Results: Initial diagnosis on HE stain was cell variant hepatocellular carcinoma, in the 8 mm biopsy, respectively suspicious for angiomyolipoma in the second case. Further immunohistochemical studies showed positivity for Vimentin, HMB45, MELAN A, S100 and actin, and negativity for OCH1E5, CK7, CK8/18, CEA, CD34, Ki67 and Factor VIII in both biopsy specimens, consistent with hepatic angiomyolipoma diagnosis, confirmed on surgical specimens too. Conclusion: Diagnosing a hepatic angiomyolipoma is not easy to do especially on a biopsy. The size of biopsy specimens plays a very important role in a correct diagnosis. Results: A 62-year-old woman presented with a 2-day history of nausea, fever and diffuse abdominal pain. CT scan revealed a well circumscribed small lesion of the pancreatic body. On arterial phase imaging, the mass was of low density relative to the pancreas without marked contrast enhancement. Based on these findings, the patient underwent surgical resection of this mass and a distal spleno-pancreatectomy was performed. Microscopic examination showed a well circumscribed but non encapsulated soft tissue proliferation consisted of blood vessels lined by a single layer of uniform flattened cells, with dilated lumen filled with red blood cells and inflammatory cells. Immunohistochemical staining confirmed the vascular nature of the lesion. The diagnosis of pancreatic hemangioma was made. Conclusion: Adult pancreatic hemangioma is an extremely rare tumor. The review of all published cases showed that this tumor often do not demonstrate the contrast-enhanced CT features typical of an hemangioma, so a poor arterial phase enhancement cannot rule out pancreatic hemangioma and the histological examination is very important in these cases. Objective: Hepatocholangiocarcinoma (HCC-CC) is an uncommon form of primary liver cancer with features of hepatocellular and biliary epithelial differentiation. It accounts for 0.4-14.2 % of all primary liver carcinomas. Many of the demographic and clinical features of this tumor remain unclear. It was previously suggested that coexisting chronic liver diseases were rarely seen in patients with HCC-CC. Method: We report a case of HCC-CC diagnosed in patient with cirrhosis. Results: A 48 year-old man presented with ascites, jaundice, vomiting and symptoms of portal hypertension. On abdominal CT scan the right hepatic segment was heterogeneous, hypervascular in the late arterial phase and low-attenuated on portal venous phase. Based on a these clinicoradiological informations, diagnosis of infiltrating hepatocellular carcinoma was made and hepatic biopsy was performed. Histopathologic examination showed, in addition to features of liver cirrhosis, the presence of malignant proliferation composed of tubular structures as well as microtrabecular and compact foci. On Immunohistochemical stainings the tumor cells expressed cytokeratins 7 and 20. Cells lining the tubular structures reacted with cytokeratin 19 allowing the diagnosis of hepatocholangiocarcinoma. Conclusion: Hepatocholangiocarcinoma is a rare primary liver cancer. Preoperative noninvasive diagnosis with conventional radiography is often difficult especially when occurring in patients with liver cirrhosis or other hepatic chronic disease. The diagnosis is frequently made only after histological and immunohistochemical examination.