Cutaneous transmission of the hands, arms, and face are the most common routes of clinical infection in humans. A pruritic papule evolves into an ulcer, followed by the development of a large painless black eschar. The eschar dries and desquamates after 1 to 2 weeks. Painful lymphadenopathy and sepsis can arise. With treatment, local cutaneous anthrax has a mortality rate of less than 1%; if the disease becomes systemic, mortality may be as high as 20% [26] . GI anthrax, while not common, occurs naturally as a result of ingesting poorly cooked, contaminated meat. Ulcers in the mouth or esophagus, or lesions lower in the intestinal tract may develop, and presenting symptoms include nausea, vomiting, diarrhea, abdominal pain, or an acute abdomen progressing to a sepsis syndrome with high mortality.