For the six areas of interest similar to both registered users and visitors, differences exist in the order of expressed interest. Three topic areas ranked similarly among the top 10 for both registered users and visitors with a difference of only one rank apart: chronic disease ranked high on both top 10 lists, ranking first for visitors and second for registered users; nutrition ranked third for registered users and fourth for visitors; and social determinants of health ranked sixth for visitors and seventh for registered users. The remaining three topic areas that both visitors and registered users were interested in included: mental health, ranking seventh for visitors and ninth for registered users; physical activity, ranking second for visitors and fifth for registered users, and, child health, ranking fourth for registered users and ninth for visitors. In the top five highest ranking common topic areas, both groups had interest in chronic diseases, nutrition, and, physical activity Characteristics of registered users of and visitors to the Health Evidence registry are provided in Table 2 . Based on the sample, 82.7% of registered users and 65.0% of visitors to health-evidence.ca are Canadian, and English is the language of preference for 98.1% of registered users and 83.3% of visitors. Upon registering to health-evidence.ca, users are asked to provide their organizational affiliation; 54.6% of users work in the field of public health or health services. As of December 31, 2010, 94.8% of registered users were subscribers to the quarterly Health Evidence tailored e-newsletter.