Secondary structures in the HRV A2 structural proteins were predicted using amino acid sequences submitted to the Jpred web server (http://www.compbio.dundee.ac.uk/,www-jpred/ submit.html). The location of a-helices and b-sheets were revealed by comparison to other picornavirus sequences using Cn3D 4.1 (http://130.14.29.110/Structure/CN3D/cn3d.shtml) (data not shown).