The results indicate that the provision of information and informed choice for routine screening is variable and generally unsatisfactory. Parents want guaranteed information provision with clear decision making powers and an awareness of the choice available to them. A paper-based information leaflet on expanded newborn screening information was reviewed by parents and found to be adequate for decision making (90%). Recommendations are made for how this information can be further developed. The difference between routine screening provision and expanded screening was not considered to be significant enough by participants to warrant formal written, informed consent. 71% of the sample deemed the informed choice model adopted within current screening provision to be sufficient, supporting use of existing procedures within a research remit. Compared to non-obese women, obese women are at higher risk for colorectal cancer (CRC), but also have lower rates of CRC screening, particularly colonoscopy. We used mixed methods to better understand these disparities. We conducted seven focus groups on CRC prevention with obese (BMI≥30) white and African American women (age≥50) who were not currently adherent to colorectal cancer (CRC) screening guidelines (N=31). Discussions and coding were guided by the Health Belief Model. Focus groups were followed by an online survey with 109 obese and 89 non-obese women. We used Chi-square to compare weight groups on screening barriers. Focus group revealed that women did not believe they were at risk for CRC and had poor knowledge of CRC prevention; they did not clearly understand the role of weight or screening in cancer prevention. Many were unaware of potential risk factors for CRC and were much more aware of potential screening barriers than benefits. Cost and time were the most frequently cited barriers to screening. Further investigation revealed that women's time and healthcare dollars were focused on more pressing co-morbidities. While most women relied on their physician to bring up important health issues, the internet was their most frequent source of prevention information. Survey data confirmed that obese women were more likely than non-obese women to agree they had too many other health costs (p=0.049) or more important health concerns that took precedence over colonoscopy (p=0.045). There were no significant differences by weight group in agreement with the more general cost and time barriers to colonoscopy. Furthermore, a higher proportion (p=0.03) of obese women (41.1%) agreed that screening tests were embarrassing compared to on-obese women (28.6%). Obese women were more than twice as likely as non-obese women to agree that they would not need a Purpose: To examine the preliminary efficacy of a culturally sensitive educational video in promoting mammography use among Chinese-American women (age ≥40) who had never or had not been screened in the past 12 months. Methods: 546 Chinese immigrant women were randomized to three groups: 1) viewed a culturally sensitive video; 2) viewed a generic video; and 3) read a fact sheet (control group). Videos, guided by the Health Belief Model, were presented in "soap opera" format, ending with physician recommendations. The cultural video particularly addressed Chinese culturally-based beliefs about cancer and was made in Chinese language. In contrast, the multiethnic generic video targeted common health beliefs about mammography, not specific to Chinese women, and was made in English with Chinese dubs.