This study explored available mathematical modeling publications on the effectiveness of combination strategies for an influenza pandemic. To obtain papers on the effectiveness of combination strategies, data for this review were identified by the authors through searches of the PubMed search engine for English language articles and articles translated into the English language. The authors used the following search terms to focus on modeling studies, and those which had a focus on pandemic preparedness and strategies -influenza and pandemic and (preparedness or strateg* or model*); influenza and modeling or modelling. The search included all published articles listed on PubMed from 1990 to 30 September 2009there were few articles on influenza pandemic planning or modeling before this period.