We observed a robust induction of antiviral IFN-b, which rose up to 620-and 5,100-fold at 16 and 36 hrs p.i., respectively (Fig. 2C ). IFN-inducible antiviral proteins Mx and 295.-OAS were induced accordingly up to 910-and 12,510-fold, respectively, at 36 hrs p.i. (Fig. 2C) .