Several polymorphisms in human PRRs [19] [20] [21] [22] [23] [24] as well as in some cytokines [25] [26] [27] , chemokines [28] and their receptors [29, 30] have hitherto been associated with an increased risk of invasive aspergillosis in susceptible hosts. Based on these observations, the objective of the present study was to investigate the role of tagging and potentially functional single-nucleotide polymorphisms (SNPs) located within the DC-SIGN, Dectin-1, Dectin-2, MCP-1/CCL2 and CCR2 genes on IPA susceptibility.