Objective: Nuclear size increases in malignant tumors and reflects DNA content, ploidy and proliferation index. Present study investigated; could nuclear morphometery differentiate histomorphologically similar paediatric malignant small round cell tumors in H & E stained sections for using in a poor resource country? Method: Morphometric analysis was done in 26 confirmed but difficult to differentiate round cell tumors histomorphologically and were analyzed by cell images from 6 different areas in each section, using Leica Q win 500 images software. Results: Nuclear measurements were obtained for retinoblastoma (9), Hodgkin lymphoma (6), Wilms tumor (3), medulloblastoma (2), Ewing's sarcoma (2), alveolar rhabdomyosarcoma (1), malignant hemangiopericytoma (1), non-Hodgkin lymphoma (1) and neuroblastoma (1). Amongst the retinoblastomas, maximum mean nuclear area percent (24.93) was seen in cases with nerve involvement and metastasis, followed by cases with only nerve involvement (21.60) and smallest area (16.57) was in non-nerve involving, non metastatic cases. Wilms tumor cases with metastasis had higher nuclear area (21.25) than non metastatic (19.47). Non-Hodgkin lymphoma nuclear area (20.03) was more than Hodgkin's (18.60). Amongst all tumors, minimum value (14.93) was seen in malignant hemangiopericytoma. Conclusion: Morphometric evaluation in paediatric malignant round cell tumors have generated useful data, and needs further multicentric confirmation for implementation. Objective: Survivin, a bifunctional protein that regulates cell division and suppresses apoptosis, may play an important role in tumorigenesis. The aim of this study was to determine survivin expression patterns in Wilms tumor (WT) and to analyze it in relation to stage, prognostic category and histological type. Method: Immunohistochemical expression of survivin was analysed in 59 cases of primary WT and in 10 normal kidney specimens uninvolved by the tumor. Results: Fifty one out of 59 cases of WT (86.44 %) showed decreased cytoplasmic survivin expression compared to the expression in normal kidney tissue. Decreased cytoplasmic expression (in all components of WT) of survivin was found significantly more often in low stage compared to high stage WTs (86.7 % vs. 27.3 %; p=0.002). Tumors of intermediate risk group showed more often decreased cytoplasmic expression of survivin in comparison to high risk group, but the difference was not significant. Decreased survivin expression was found more frequent in WTs with diffuse anaplasia and in epithelial WTs compared to other histological types, but without statistically significant difference. Conclusion: Decreased survivin cytoplasmic expression may be associated with the favorable prognosis WT. Objective: Hepatic tumors accounted 5 % of congenital neoplasms. Mesenchymal hamartoma of the liver is a rare benign tumor of children. We report a case of hepatic mesenchymal hamartoma in a premature male neonate. Method: A premature neonate born at 33 gestational weeks from 34 year-old mother, G3P3 with non-consanguineous marriage; prenatal ultrasonography showed a fetal macrosomia, a highly vascularized abdominal mass occupying two-third of the abdomen and displacing the bowel loops associated with poly-hydramnios. The newborn examination showed abdominal firm lump. Ultrasound found and anterior highly vascularized mass displacing the left lobe of liver. The infant died few hours later. A complete autopsy was performed. Results: External examination showed a male neonate anatomically of 34-35 week having an increased periombilical diameter and a macrosomia, ascitis, pulmonary hypoplasia, cardiomegaly, pleuropericardial effusion, liver tumor developed in left lobe and dilation of renal vessels. Histologically the tumor showed a mixture of normal liver tissues with blood or lymphatic vessels, bile ducts within an abundant edematous and myxoid stroma. Conclusion: In neonate and fetus, prenatal diagnosis is possible by ultrasonography. Large tumors can affect the viability of the newborn. Adequate excision is curative in most of cases.