A set of 54 ITs was measured on a population of 443 pigs three weeks after vaccination against M. hyopneumoniae (Tables 1 and 2;  Table S1 ; Figure 1 ). These ITs comprise either traits related to IR (phagocytosis, lymphocyte proliferation, cytokine production after in vitro stimulations, levels of total and specific antibodies, levels of acute phase proteins) or traits related to total leukocyte and leukocyte subpopulation counts. The various characteristics and descriptive statistics of the traits measured on each animal of the studied population (n = 383 to 442) are summarized in Tables 1  and 2 . Among the cell-mediated ITs evaluated after diverse stimulations, higher responses in cytokine levels were observed after phorbol myristate acetate (PMA)-Ionomycin (PMAIONO) stimulation compared to lipopolysaccharide (LPS) and concanavalin A (CONA) stimulations, except for IL2 production. Conversely, a higher lymphocyte proliferation was detected after CONA and PMAIONO stimulations than after LPS stimulation.