Analysis at different time points after naphthalene-treatment demonstrated a gradual increase in the number of eGFP pos bronchial epithelial cells that was evident on day 2 and maximum increase of 15-fold over control levels by day-9 post-naphthalene treatment ( Figure 8B ). Up to day-2, the increase in eGFP pos airway epithelial cell numbers involved CGRP pos and CGRP neg -CC10 lowcells ( Figures 8C and D) . Thereafter, although the total number of eGFP pos -CGRP pos cells remained stable from days 2-9, a wave of eGFP pos -CC10 low -CGRP neg cells that reached maximum around day 3 was followed by a wave of eGFP pos -CC10 pos cells that reached plateau around day-9 ( Figure 8D) .