To further investigate whether MBL would modify the inflammatory response upon pdmH1N1 and H9N2/G1 virus infection, a panel of 14 proinflammatory cytokines and chemokines were examined in the lung homogenates collected from the infected MBL WT and MBL KO mice. The simultaneous profiling of the cytokines and chemokines was examined by using bead-based suspension array, which could allow the sensitive and specific detection of these proteins in the available amount of lung homogenates.