In liver, P. emblica and P. urinaria inhibited HepG2 cell growth and five other cancer cell lines [145, 146] . Progallin A isolated from the acetic ether part of the leaves inhibited the proliferation of BEL-7404 cells, upregulated Bax, and downregulated Bcl-2 expression [147] . Defatted methanolic fruit extract of P. emblica suppressed carcinogen-induced response in rat liver with diethylnitrosamine-induced hepatocarcinoma [148] .