No statistically signifi cant differences were observed in minor allele frequencies for the 5 MBL2 SNPs examined (Figure 1 ) or the prevalence of pooled MBL2 genotypes (Figure 2 ) between the case-patients and the NHANES reference sample with all case-patients examined together or with black and white racial groups examined separately. In a subgroup analysis, the minor allele frequency of rs5030737 was signifi cantly less common among case-patients <5 years old than in the reference sample (2% vs. 7.2%; p = 0.02). Among low producers of MBL, we observed an estimated odds ratio of 7. Table 3 ). Low-producing MBL2 genotypes were also associated with an approximate 3-fold increased risk for bacterial coinfection in general and with S. aureus infection overall, but these associations did not reach statistical signifi cance. Characteristics of case-patients with invasive MRSA coinfection are shown in Table 4 .