Objective: The TASTE (technological platform and repository of high quality images and slides) project aims at developing a novel tele-pathology system by means of modern ICTs (Information and Communication Technology) and is addressed to technicians and doctors. Method: Histological and cytological preparations are the basis for pathological diagnosis performed in daily practice throughout Europe in a number of several millions per year and correctness and reproducibility of such diagnosis are heavily dependent on the technical quality. Yet, quality is variable in different places and countries, related to school level, technicians' dedication, standard of apparatuses and reagents. Variation in technical quality of the preparations prevents their open circulation at European level and precludes optimal diagnosis. Results: The TASTE project tackles these problems by building-up an ICT environment TASTE System where professionals from different countries will submit, via Web, "virtual slides" of their own preparations to a panel of internationally recognized experts who will give comments and suggestions on the quality of the preparation. Conclusion: The present approach (unprecedented at world level) will fuel a Web-based community, aimed to a levelling and improvement of histopathological and cytopathological preparations, thus leading to an innovative training and more reproducible diagnosis, a basic requisite for disease treatment.