Method: We report two cases of a 52-and 64-year-old women, who presented with severe nephrotic syndrome, rapidly progressive chronic kidney disease and lymphoproliferative disorders. Glomerular crescents were present in about 30 % of both renal biopsy specimens (18 of 54 and 9 of 27 glomeruli, respectively). Immunohistochemical analysis, immunofluorescence and an electron microscopy (EM) studies were performed. Results: Renal biopsy showed a deposition of an amyloidlike extraneous substance in the mesangium, as well as within the glomerular basement membranes. Congo red staining was negative. The EM examination revealed FGN. Conclusion: FGN must be included in the differential diagnosis of rapidly progressive chronic renal disease. EM confirm the diagnosis of FGN, which suggests a poor outcome. Objective: Urachal carcinomas represent less than 1 % of bladder-related cancers. Most are adenocarcinomas, but urothelial, squamous and small cell carcinomas may occur. There are pathological criteria for assessing an urachal origin. A specific staging system is lacking for these tumors. Method: A mass of the bladder dome was found in two 56 and 58 year-old men. A 76 year-old woman presented an urachal cyst. CT-scan revealed no other tumors and partial cystecomy was performed. Pathological examination showed partially cystic adenocarcinomas, one enteric type G2, and two mucinous type G1. Two tumors extended into the bladder mucosa and one was limited to the urachal cyst. Surgical margins were negative. Immunostainings were positive for CK7, CK20, CDX2, cytoplasmic beta-catenin, and negative for p63. Results: With a follow-up of 1, 6 months and 6 years, all patients are free of disease. Conclusion: No TNM classification exists for urachal carcinomas. Specific staging systems have been proposed by Sheldon, and more recently by the Mayo Clinic. Two cases are Sheldon IIIA/Mayo Clinic II, and one Sheldon II/Mayo Clinic I. Since stage, grade and surgical margins are the main prognostic factors, a clear and relevant staging system is needed for these rare carcinomas. Objective: Renal cell carcinoma (RCC) with two different histologies must be included in the unclassified group (WHO classification). Whether these cases should be included in this histological subgroup or be considered hybrid RCC is a matter of debate. We report one of such cases in which papillary and chromophobe phenotypes meet. Method: A 5 cm in diameter asymptomatic left renal mass was discovered incidentally in the radiological follow-up of a breast carcinoma diagnosed 12 years before in a 62 yearold woman. Follow-up showed right adrenal gland metastasis. Patient died 12 months later. Results: Grossly, tumor well circumscribed, tan-yellow, with haemorrhagic and necrotic areas. The neoplasm showed two different histologies clearly defined: One showed solid nests of polyhedral cells, with eosinofilic cytoplasm, central and hyperchromatic nuclei, occasional mitosis recapitulating chromophobe RCC. The other component presented a well defined tubulopapillary growth pattern typical of papillary RCC. Focally sarcomatoid transformation, with tumor necrosis and chronic inflammation. By immunohistochemistry, chromophobe and papillary areas retained their specific phenotypes. Conclusion: Hybrid renal carcinomas do exist, but they are most probably hidden in the unclassified group of renal tumors. However, the exact histological context for which a renal neoplasm deserves the name "hybrid" remains to be defined. Objective: Renal cell carcinoma with thyroid-like follicular pattern is a rare histological subtype of renal carcinomas that has been very recently described. Method: A 3.3 cm in diameter asymptomatic left renal tumor was discovered during the study of a macroscopic hematuria in a 32 years old man. The lesion was organconfined. Results: Grossly, the tumor was a well circumscribed, solid, brown and homogenous intraparenchymatous nodule. Proliferating cells were arranged in a microfollicular pattern with colloid-like material resembling thyroid adenoma. Cells displayed low grade nuclear features and had eosinophilic cytoplasm. Some areas showed a solid pattern of growth resembling an oncocytoid neoplasm. By inmunohistochemistry, the tumor was negative for thyroglobulin and TTF1, and positive for EMA, CK7, AE1/AE3, and ecadherin.