HBoV1 infection has been linked with mild-to-severe, primarily lower respiratory tract infections in children, frequently in association with other viral infections [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24] [25] . HBoV1 has also been detected in stool samples, although association with diarrhea appears weaker than with respiratory symptoms [26] [27] [28] [29] [30] [31] . HBoV1 strains show a very low degree of genetic variability worldwide [32, 33] .