Ethanolic extract of Folium Murraya Koenigii and boiled extract of Herba Polygonis Hydropiperis showed 80% and 50% of the activities of streptomycin 10 μg against M. smegmatis respectively. These extracts also exhibited antimicrobial activities against S. aureus and B. subtilis. Additionally, the boiled extract of Herba Polygonis Hydropiperis was active against C. albicans. Boiling was essential for the active principles to be removed from the laksa plant, as blended and water macerated extracts showed little antimicrobial activities ( Table 3 ). The duration of the boiling process also affected the antimicrobial activities of laksa plant, whereby herbs boiled for 20 minutes were more active against S. aureus and M. smegmatis. The aerial parts of Herba Houttuyniae and rodent tuber were only active against B. subtilis and S. aureus respectively. The leaves and Rhizoma Arachis Hypogea, Rhizoma Imperatae, Rhizoma Typhonium Flagelliforme, and the leaves and stems of Epipremnum pinnatum did not show any antimicrobial activities.