In the ellagitannin study mentioned earlier, Lagerstroemin exhibits glucose transport stimulation at 40 mM with an EC 50 of 80 mM (22) . In comparison, aand b-PGG exhibit activity at a concentration as low as 10 mM with EC 50 of 17 and 18 mM (39) . In other words, aand b-PGG are about five times more potent than Lagerstroemin in stimulating glucose transport. We would like to emphasize that both aand b-PGG possess the adipogenesis inhibitory activity exhibited by the banaba extract (28) and by TA (29) . This suggests that these two activities are associated with the same molecules. It also indicates the functional differences between insulin (glucose transport inducing and adipogenic) and PGG (glucose transport inducing but anti-adipogenic). Both compounds may have the potential to reduce hyperglycemia without increasing adiposity, a very desirable combination of properties that insulin lacks.