IL-1β was associated with marked thrombocytopenia with OR = 1.058 (CI, 1.012-1.106) in dengue patients. TNF-α was inversely related to thrombocytopenia with OR = 0.978 (CI, 0.962-0.995) (Table 2, Figure 2 ). Considering platelet counts as a continuous variable for statistical analysis with a Gaussian family, it was possible to determine that IL-8 (P = 0.0434) and MCP-1 (P = 0.0146) levels are inversely related to their counts, displaying therefore an association with thrombocytopenia, while MIP-1β (P = 0.0114) confirms its association with higher counts -normal or tending to normal (Table 3) .