Results: Grossly, the left tonsil featured a 1.2 cm well circumscribed grey lesion. Histologic examination showed a proliferation of spindle to ovoid cells arranged in fascicles with swirling qualities admixed with scattered lymphocytes. Frequent mitoses and apoptotic bodies were seen but no "tumoral" necrosis was recognized. Tumor nests were separated by thin stromal septi containing a prominent glioblastoma-like microvascular proliferation with focal formation of glomeruloid tufts. The tumor cells were immunoreactive for CD21, CD23 and vimentin. Objective: Salivary gland tumors reveal a broad morphology and immunohistochemistry may be helpful. Method: We examined 12 mucoepidermoid (MEC), 8 adenoid cystic (ADC), 3 asinic cell (ACC) and 4 salivary duct carcinomas (SDC); 2 myoepitheliomas (ME), 5 basal cell (BCA), 31 pleomorphic adenomas (PA) and 18 Warthin tumors (WT) for SMA, Calponin, S100, CD10, GFAP, p63, CEA, GCDFP15, GLUT1, 34BE12, CK14, CK19, CD117 and Galectin3, using tissue microarray.