Overall, OLB findings led to alteration therapy for 30 of 41 patients (73%). After OLB, 18 patients were administrated high-dose corticosteroid therapy (1 g/day methylprednisolone in divided doses for three days) and seven patients were treated with low-dose corticosteroid therapy (2-3 mg/kg per day methylprednisolone in divided doses). Three patients received co-trimoxazole for Pneumocystis carinii pneumonia. Antibiotics were changed in one patient and discontinued in one patient on the basis of pathological findings. Treatment was not changed in 11 of 41 patients (27%). Table 3 presents comparative results for patient characteristics, complication rates, alterations in treatment, and survival rates of patients with specific and nonspecific pathological diagnoses by OLB. The rate of treatment alteration was higher in the nonspecific pathological diagnosis group than in that with a specific diagnosis (56% versus 87%; p = 0.0243). No other significant differences between these two groups were noted.