Objective: MicroRNAs are small non-coding RNA molecules that regulate a large number of cellular pathways and deregulation or altered expression of miRNAs is associated with many disease states. The function of the Fallopian tubes appears to involve orchestrated spatiotemporal alterations in transcriptome profiles, the regulation of tubal gene expression and function by miRNAs may thus be of primary importance in tubal ectopic pregnancy. Method: Both implantation sites and non-implantation sites of Fallopian tubes from women with EP and decidual biopsies from women undergoing therapeutic surgical termination of pregnancy were collected and analyzed by miRNA array. The unique miRNA profiling results were validated by TaqMan qRT-PCR, and bioinformatics' analysis was employed to further predict the miRNA targets. Results: A total of 47 miRNAs were differentially expressed in implantation sites compared with those in non-implantation sites of Fallopian tubes after comparison of decidual miRNAs, among which 19 were up-regulated while 28 are down-regulated. The miR-424 was significantly increased, whereas let-7i, miR-149, and miR-182 were significantly decreased. Differentially expressed miRNAs were predicted to be related with several signaling pathways in normal intrauterine implantation. Conclusion: Our findings establish an miRNA signature associated with tubal implantation and provide the experimental basis for further understanding the molecular and cellular mechanisms of initiation and development of tubal EP in humans. Lung is an organ that can sense any perturbation of the air, due to its constant interaction (long live) of the air. Our hypothesis was that lung could be an organ sensor of climatic change observed today. Method: This preliminary study analyzed the expression of 3 isoforms of the genes of Hsp90. The cases were chosen from archive of autopsies from 1970 to 1979, with different diagnosis, and were matched in sex and age with a same number of cases chosen from 2000 to 2009. The expression was studied by RT-PCR from lung tissue embedded in paraffin, 20 samples of each decade. Results: The expression levels of Hsp90 were normalized to β-actine. We found expression in six cases of 2000-2009: five for Hsp90AA1-2, and 1 for Hsp90AB1, one case expressed both. Their matched cases in 1970-1979 never expressed any isoform. The cause of dead in all cases doesn't fit with any pattern. Conclusion: With these results we propose than the lung could be a sensor of global warming, and the expression of these genes could be molecular markers of this climatic change.