HLA-A*0201 is a global common HLA type, which occurs at high frequencies in populations of northern and southeast Asia and North America [18] . In this study, we selected nine peptides that might be potential vaccine candidates for human influenza A using the HLA-peptidebinding prediction program. Two novel epitopes for HLA-A2 specific H5N1 NP were found, namely NP373-381 AMDSNTLEL (NP373) and NP458-466 FQGRGVFEL (NP458). We further repeated the prediction process to investigate the binding of the two identified epitopes to other HLA types (Tab. I). We found that these two epitopes might be able to bind to other HLA types, and therefore further experimentation may be required to confirm the prediction. An ideal vaccine capable of counteracting infectious viruses should be able to trigger both neutralizing antibody production and the cytotoxic T-cell response which are critical processes in eliminating the virus during a viral pathogenesis. As previously mentioned, current studies of H5N1 vaccines have mainly focused on the generation of neutralizing antibodies [3, 11] . Another research stream involves the study of cell-mediated immunity against H5N1. Epitopes have been found in different internal proteins of influenza virus and with different HLA types [9, 20, 22, 25] .