Results: D2R pre-treatment was higher in patients than in controls. No significant differences were found between pre-treatment A and B phenotypes. D2R was higher post-treatment (paradoxical response) in a B patient (L-dopa induced dyskinesias, poor outcome), whereas it rapidly decreased in two A patients with an excellent L-dopa response. Coordinated regulation of DAT and D2R, as well as VMAT and GABAVT after L-dopa doses increase was observed.