One possible strategy to reduce the impact of a respirator shortage would be to apply a biological decontamination process (e.g. such as those used in hospital settings for infection control) to inactivate the influenza virus that may be on the FFR. If the treatment did not deteriorate the FFR or leave potentially toxic residues on the FFR, then it could be available for subsequent reuse by the original user. Until recently, no data were published on the effects of decontamination on FFR performance. Viscusi et al. (2007) measured the laboratory filtration performance of one N95 model and one P100 model FFR that were exposed to 20 different biological decontamination treatments. They found that filtration performance after onetime decontamination treatments using bleach, ethylene oxide (EtO), microwave oven irradiation, ultraviolet germicidal irradiation (UVGI), and hydrogen peroxide (vaporized and liquid forms) was observed to have filter aerosol penetration values that remained less than the National Institute for Occupational Safety and Health (NIOSH) certification criteria. It was also found that decontamination using an autoclave, 160°C dry heat, 70% isopropyl alcohol, and soap and water (20-min soak) caused significant degradation to filtration efficiency.