Recently, the same group of researchers showed that the aqueous extract of another Chinese herb, Salvia miltiorrhiza (Danshen), traditionally used to treat cardiovascular disorders, was also protective against lethal endotoxemia and sepsis by decreasing HMGB1 levels in vivo (46) . As for the Dang Gui extract, the Danshen extract was administered 24 h after the onset of sepsis yet still rescued mice. As a potential anti-influenza treatment Danshen may have a double-pronged attack, as it also possesses anti-viral activity (47, 48) .