Only 27 studies consisting of 3,444 PICU survivors met our inclusion criteria. The small numbers, heterogeneity of the 4  yes  yes  yes  yes  no  6  no  no  yes  yes  no  8  no  no  yes  yes  yes  9  no  yes  yes  no  no  12  yes  yes  yes  yes  no  14  yes  yes  yes  yes  no  20  yes  yes  yes  yes  no  22  no  no  no  yes  no  23  no  no  yes  yes  yes  27 yes studied populations and the used measurement tools, the frequent use of non-validated measurement tools and the various aspects of outcomes studied make aggregation of the data and, therefore, strong conclusive statements difficult.