A very few children do not require any treatment and recover spontaneously. In the majority of cases, treatment with immunosuppressive, anti-inflammatory, or anti-fibrotic drugs is required for weeks, months or even years [1, 9, 61] . Various drugs discussed below can be used, but no guidelines for treatment of ILD in children have been proposed so far. The major reason is the very limited number of pediatric patients available for a prospective clinical trial. In addition, controlled studies with a placebo arm are unacceptable because of the poor prognosis of untreated cases and the reported efficacy of anti-inflammatory therapies in a number of pediatric ILD.