It is important to note that the results we present here are preliminary, a proof of concept for the method which requires further verification and refinement. In particular, it would be useful to develop an experimental assay which could measure the infecting time for a given strain, in the same way that single-cycle viral yield experiments give an approximate measure for the latent infection period. It is also of interest to design a set of experiments which may be less expensive and laborious than those presented here, perhaps using fluorescent or photographic observations of cell cultures rather than virus titrations, and which can identify a fuller set of viral kinetics parameters. We are currently designing competition experiments for the A/Brisbane/59/2007 WT and H275Y mutant strains in which the predictions which follow from the parameters extracted here can be tested directly. When verified, the basic method of analyzing parallel plaque and viral yield experiments introduced here should be useful in other contexts. For example, the investigation of other drug-resistant viruses (e.g., that of the pandemic A/H1N1), the rapid characterization of fitness for emerging strains, and assays measuring the activity of new antivirals would all be enhanced through the application of our method.