An outbreak was considered contained, if the daily infection rate did not exceed five cases, for seven consecutive days. Once contained, a region was simulated for an additional 10 days for accurate estimation of the pandemic statistics. A 2 5 statistical design of experiment [89] was used to estimate the regression coefficient values of the significant decision factors and their interactions (see Section 2.3; the values of adjusted R 2 ranged from 96.36% to 99.97%).