A recent review revealed that triterpenoids, which are also found in Glycyzirra glabra extract, had antitumor activities. Triterpenoids could induce apoptosis in various cancer cells by activating various proapoptotic signaling cascades. The molecular mechanisms involved include inhibition of various oncogenic and antiapoptotic signaling pathways and suppression or nuclear translocation of transcription factors including NF-κB [110] . In a human hepatoma cell line, the expression of junB mRNA, a tumor suppressor gene, and JUNG protein is highly increased by GL treatment [111] . Zhao et al. studied the β-Cyclodextrin/glycyrrhizic acid functionalized quantum dots (β-CD/GA-functionalized QDs [112] , and found that this drug has proapoptotic effects in hepatocarcinoma cells. β-CD/GA-functionalized QDs triggered G0/G1 phase arrest and induced apoptosis through an reactive oxygen species mediated mitochondrial dysfunction pathway.