While some studies have shown that AST and ALT values differ between DF and DHF [3, 4, 8] , few studies support AST or ALT as an independent predictor of DHF [23] . Two studies in Singapore found liver aminotransferase levels to be significantly elevated among DF and DHF patients [12] and survivors and nonsurvivors of dengue [24] on univariate analysis, but this association was lost after adjusting for confounders on multivariate analysis.