In order to further characterize the genome of the HRV-Cc subspecies, for which no full-length sequence was yet available, we sequenced the remaining genes that covered the whole coding sequence and 39UTR of N10 strain, which was chosen as the representative of this subspecies (Tables 2 and 3 ). The full-length N10 genome sequence was compared to those of the HRV-Ca subspecies strains C024, C025 and C026, and to that of N4 strain, which was sequenced as the representative of the HRV-Ca subspecies. The genome sequences were also compared to those of the HRV-A strains N13 and R44, and to the HRV-B strains R14 and R52 (Table 4 ). The full-length nucleotide sequence of N10 strain contained 7111 nt, excluding the poly(A) tract, which was shorter than sequences from HRV-A and HRV-B strains, but similar to those of HRV-Ca strain N4 and other related strains (C024, C025 and C026). The 2144 aa lengths of the polyprotein and of each of the individual proteins of N10 were slightly different from those of HRV-A and HRV-B species, but similar to those of other HRV-C strains. The most divergent amino acid length between HRV was observed for the VP1 protein that was shorter in HRV-C species ( Table 4 ). The unique putative cleavage (M/S) site between VP4 and VP2 protein identified previously for QPM, C024, C025 and C026 strains [20] was also observed for N10 and N4 strains. It was different from those of the HRV-A strains N13 and R44 (Q/S), and from those of the HRV-B strains R14 and R52 (N/S) (data not shown).