Pairwise LD of D' and r 2 analyses were performed using Haploview (Broad Institute of MIT and Harvard, USA, version 4.0). 262 contingency tables were used for comparing the differences of allele frequencies and 263 contingency tables were used for detecting the differences of genotype frequencies between cases and controls. Allelic, dominant, recessive and additive genetic models were used to test the association between each SNPs and T2D. Multivariate logistic regression analysis was used to assess the significance of covariates and adjusted for confounders in the association of genetic factors with T2D.