Nineteen reviews focused on 13 single herbs or herbal preparations, while the remainder (39 [67%]) addressed broad questions, in which 34 reviews concerned multiple Chinese herbs or multiple formulations of Chinese herbs, 5 reviews involved a family of herbal medicines sharing similar efficacy, including Huangqi type formulations (including Huangqi injection and Huangqi-Danggui mixture), Chuanxiong preparations (including Nao-an capsule, Xifeng wan and Apoplexy Preventing Dry Ointment Powder), Dan Shen agents (including Compound Danshen Dripping Pill, Compound Danshen injection, Danshen injection, Yiqi huoxue injection, and Quyu huatan xiezhuo fang) and Sanchi (including Xinnaotai, Sanchitongshu capsule, Naoming injection, Xuesaitong soft capsule, Sanqitongshu capsule, Xuesaitong and Xueshuantong injection). Of the 39 reviews, 4 didn't include any primary study, of the remaining reviews (n = 35), the median number of herbal medicines involved was 6 within a range of 1 to 71, results of different herbal medicines were pooled in 9 reviews, in which 7 reviews pooled the results of all Chinese herbal medicines, one review pooled all Danshen agents, and one pooled Sanchi. Table 1 presents a summary of OQAQ items of the included reviews, the mean score (item 10) was 5.05, 95% CI (4.58, 5.52). 41 of 58 reviews attempted to minimize bias during the selection of studies by at least two reviewers independently select eligible studies.