Treatment of human macrophages derived from blood monocytes required concentrations of PSG1-Fc of 50 lg/ml to observe a significant induction of VEGF-A over FLAG-Fc (data not shown). While we found that monocyte-derived dendritic cells secreted TGFB1 in response to PSG1 treatment, VEGFA secretion was not induced by PSG1-Fc even at the highest concentration tested (80 lg/ml; data not shown).