Objective: Health alert concerning breast implants brand PIP led to a review of patients harboring these prosthesis and in many cases replacement by new ones. Anaplastic lymphoma described in these patients has been an additional problem to be faced by plastic-surgeons and pathologists. Method: Ninety two cases of women with breast implants were studied. Most of them had PIP implants (although no information of prosthesis type was available in all cases). Eighty of them presented with ruptures of different size. After implant replacement, histopathologic analysis of fibrous capsules and liquid from seromas in periprosthetic cavities was carry out. Following FDA recommendations, immunohistochemical studies to rule out lymphoma was performed in 85 cases. Results: Fibrous capsules showed synovial metaplasia in all cases. Morphology was practically identical that in real articular synovial cells, and occasionally intracavitary nodules were seen detached from the surface in a process similar to synovial chondromatosis. No cases of lymphoma were seen and no expression of CD30 or ALK markers occurred. A case of pericapsular ductal invasive carcinoma was discovered. Conclusion: Synovial metaplasia seems to be very common in capsules around breast implants. Development of conventional breast carcinoma is probably much more frequent than lymphomas independently of the possible implant influence.