Methods. An 80 year-old woman was treated for a 3×2,2 cm multinodular mass in the scalp. One month later an ultrasonography of the left breast showed a 5,5 cm mass which was excised with clean margins. Axillary lymph nodes were free of metastasis. Results: Results. The dermal tumor presented well demarcated basaloid epithelial nests with squamous differentiation focally connected with the epidermis. They showed peripheral palisading and high nuclear grade with pleomorphism, brisk mitotic activity and multiple prominent nucleoli. Atypical cells, arranged as strips, nests or isolated elements, were observed at the tumor edge, separated by a grey-zone from the overlying malpighian epithelium. Immunostains were positive for cytokeratins, melanocytic (S-100/HMB-45/ MART-1) and neuroendocrine (CD56/NSE/Cromogranin) markers. The 4,8 cm breast tumor corresponded to a high grade metastatic BCC with reactivity for epithelial markers, S-100 and CD56. Objective: Pyoderma gangrenosum (PG) was described at first by Brocq and named by Brunsting et al. in 1930. Superficial granulomatous pyoderma (SGP) was described as a variant of PG in 1988. We present three cases of this rare variant. Method: There were two women and one man with age ranging from 40 to 78 years. All of them had a long history of a slowly enlarging, eritematous and ulcerative plaque in different areas including leg and breast skin. A biopsy was performed in all cases. Results: The superficial dermis showed neutrophilic inflammation with an admixture of granulomatous inflammation and sinus formation. There wasn't vasculitis and fat tissue was not affected. Conclusion: SGP is a rare variant of PG. Diagnosis of this entity generally is made on the basis of skin biopsy results with all features mentioned previously and a typical clinical appearance. Most of times, these lesions are diagnosed as granulomatous dermatitis, thinking in infectious pathology. This is the most important differential diagnosis, because SGP is responsive to corticosteroids. The pathogenesis of PG is unknown, though is now believed to altered neutrophil chemotaxis and some authors suggest that SGP may be a delayed-type hypersensitivity to an unknown antigen. Pathergy is the inciting factor in several patients.