Wearing gloves while caring for patients as part of droplet precautions was strongly associated with a lower risk of having had pandemic (H1N1) 2009 virus infection. Use of gloves was highly correlated with use of gowns, masks, and eye protection on logistic regression (results not shown). This fi nding confi rms the great importance of PPE in preventing transmission of respiratory viruses in the health care setting and may explain why HCWs with defi nite exposure to infl uenza in the workplace, in addition to probable exposure in the community, do not have higher rates of infection than those with only community exposure.