This article aims to address the non-formal educational strategies used in the two countries. It begins with an overview of the HIV epidemic in the Philippines and then in Taiwan, as these two nations face similar situations in their epidemics, with some very important distinctions. Following this overview, we describe the formal and non-formal educational activities being conducted in each country, which national and local organizations are directing to high-risk, vulnerable populations. We highlight social-structural and environmental approaches that have been integrated into the healthcare delivery systems.