-P1: base case (no controls), -P2a: treatment of index cases only, -P2b: treatment and quarantine index cases, -P3a: as per P2b, trace household contacts only, with 10 days prophylaxis, -P3b: as per P2b, trace household contacts only, with 2 days quarantine, -P3c: as per P2b, trace household contacts only, with both prophylaxis and quarantine, -P4a: as per P2b, trace all contacts, with 10 days prophylaxis, -P4b: as per P2b, trace all contacts, with 2 days quarantine, and -P4c: as per P2b, trace all contacts, with both prophylaxis and quarantine.