In the present study, a recombinant baculovirus displaying the RSV G protein (Bac-RSV/G) was constructed. Our results clearly show that strong humoral and cellular immune responses were induced by intranasal administration of Bac-RSV/G in a mouse model. Importantly, complete protection against RSV challenge without vaccine-induced illness was observed in Bac-RSV/G-immune mice, suggesting that vaccination of Bac-RSV/G could be utilized as a prophylactic vaccination regimen against RSV infection.