The purpose of this project is not simply to generate lists and information. It is to provide a distillation of disease and phenotype information that can be used in dissecting the complexities of human disease and mouse biology. Now that we have generated GENE-to-disease/ phenotype summaries and DISEASE/PHENOTYPE-togene summaries for both mouse and human, they can be used for systematic analysis, comparison, and integrating of orthologous data with the goal of providing higher order interpretations of human disease and mouse genetically determined phenotypes.