Since 6 years had passed since the patients and healthy volunteers who participated in our Previous GWAS [10] were first recruited, we updated the case (n = 418) and control (n = 300) groups based on the latest clinical information. In total, 7 samples from the case group and 11 samples from the healthy control group were removed. The population for the reanalysis finally ended up with 411 POAG patients, comprised of 215 HPG and 196 NPG patients, and 289 controls. The Previous GWAS data was obtained by GeneChipH Human Mapping 500 K Array platform (Affymetrix) containing 500,568 SNPs. The quality control for the reanalysis was performed by using the same QC filters as used in the Present GWAS. Genotype data derived from the particular locus for combining with the Present GWAS data was extracted from these filtered SNPs.