Customized antibody arrays, consisting of pairs of capture and detection antibodies against 43 proteins, were utilized (SDF-1), IGF1, IFNG, IGFBP3,  IGFBP4, IGFBP6, IL-1A, IL-1B, IL-1R1, IL-2, IL-4, IL-5 . Antibody array fabrication, processing, data extraction and analysis were performed as previous described [31] .