The human enteroviruses (HEVs) are the closest genetic relatives of the HRVs but they belong to the genus Enterovirus. HEV strains are classified into four species (A-D) and some have been implicated in ARTI [17] . Similar to the major group HRVs, some HEVs have been shown to use ICAM-1 as their primary cellular receptor [18] . Other host molecules employed by HEVs include the decay accelerating factor (DAF) [19, 20] , poliovirus receptor (PVR) [21] and coxsackie-adenovirus receptor (CAR) [22] . Under a proposal currently before the International Committee on Taxonomy of Viruses (ICTV), HRV and HEV strains will be combined into the genus Enterovirus, at the expense of Rhinovirus, an issue of contention for decades [23] .