In conclusion, mixed HBV genotypes infection with many novel recombinants at one point in time ended up with just one genotype 18 months later in this study. This may indicate that the detectable mixed infection and recombination have a limited time window due to the sensitivity of detection or strong selection power of the host. Also, as the recombinant or recombinant-like nature of HBV precludes the possibility of a ''true'' phylogenetic taxonomy, a new standard may be required for classifying HBV sequences.  Identifying Live Bird Markets with the Potential to Act as Reservoirs of Avian Influenza A (H5N1) Virus: A Survey in Northern Viet Nam and Cambodia Wet markets are common in many parts of the world and may promote the emergence, spread and maintenance of livestock pathogens, including zoonoses. A survey was conducted in order to assess the potential of Vietnamese and Cambodian live bird markets (LBMs) to sustain circulation of highly pathogenic avian influenza virus subtype H5N1 (HPAIV H5N1). Thirty Vietnamese and 8 Cambodian LBMs were visited, and structured interviews were conducted with the market managers and 561 Vietnamese and 84 Cambodian traders. Multivariate and cluster analysis were used to construct a typology of traders based on their poultry management practices. As a result of those practices and large poultry surplus (unsold poultry reoffered for sale the following day), some poultry traders were shown to promote conditions favorable for perpetuating HPAIV H5N1 in LBMs. More than 80% of these traders operated in LBMs located in the most densely populated areas, Ha Noi and Phnom Penh. The profiles of sellers operating at a given LBM could be reliably predicted using basic information about the location and type of market. Consequently, LBMs with the largest combination of risk factors for becoming virus reservoirs could be easily identified, potentially allowing control strategies to be appropriately targeted. These findings are of particular relevance to resource-scarce settings with extensively developed LBM systems, commonly found in South-East Asia. First detected in 1996 [1] , highly pathogenic avian influenza virus subtype H5N1 (HPAIV H5N1) has spread across 3 continents and is now considered to be endemic in several South-East Asian countries and Egypt. Due to its potential to recombine with human influenza strains to produce highly virulent reassortants [2] , ongoing circulation of HPAIV H5N1 continues to be a major public health concern.