Silymarin possesses various pharmacological activities, including hepatoprotective, antioxidant, anti-inflammatory, anticancer, and cardioprotective effects. Silybum marianum is the most well-researched plant in the treatment of liver diseases. Silymarin has been shown to have a variety of anti-inflammatory effects on liver, including mast cell stabilization, inhibition of neutrophil migration, and Kupffer cell inhibition [53] . Silymarin is commonly prescribed in cases of cirrhosis or viral hepatitis.