Á Scientific understanding of pathogen and pathogen-humanenvironment interaction is the foundation for integrated InGBSV; Á Emerging technology being developed by the R&D community for basic and applied life science advancement provides tremendous support for InGBSV; Á InGBSV can be 'jump started' with initial focus on information science and technology applications and integration; Á Challenges were recognized as multidimensional, but opportunities for developing a GBSV exist and are invigorated by international health security policies; Á Formulating unconventional partnerships and establishing an advanced concept demonstration is an effective near-term path forward.