A total of 117 HIV-uninfected patients with cryptococcal meningitis were included. Subjects from both the patient and control groups were of Chinese Han ethnicity. Clinical information and predisposing factors of the patients are summarized in Table 1 . Of the 190 healthy control subjects, 111 were male (58.4%). The median age of the control subjects was 44 years (range, 12-79 years).