When this assay was applied to orthomyxovirus infection, we likewise observed a dose-dependent inhibition of influenza A/ WSN antigenome levels relative to vehicle treated controls (figure 7B). Parallel quantification of genome copy numbers of released progeny virus demonstrated that an approximate .100fold drop in relative viral antigenome levels correlates to a .10,000-fold reduction in genome copies of released progeny virions ( figure 7B) .