Background: Research has shown that social support and certain coping strategies attenuated cardiovascular reactivity (CVR) to stressful circumstances. This hypothesis has not been tested in an immigrant population. The current study assessed the effects of perceived social support and problem-focused and emotionfocused coping on CVR to stress among Chinese immigrants in the New York City area. Method: First generation Chinese immigrants (N=150; Mean Age=53 years old; 86 Females, Average Length of Stay in the United States=20 years) were recruited from the New York Downtown Hospital in Chinatown. Following the study description and informed consent procedures, participants completed questionnaires which assessed social support and their use of problem focused and emotion focused coping strategies. Following an 8-minute adaptation period, participants recalled a stress-provoking event related to their immigration experience in a semi-structured interview format. Recovery was monitored for 20 minutes and participants were debriefed. Blood pressure and heart rate were monitored at 2 minute intervals during baseline and recovery, and 1 minute intervals during the interview. Result: Hierarchical multiple regression analysis revealed that the interaction perceived social support and emotion-focused coping is associated with low baseline SBP, β=-.18, t=-2.19, p<.03. However, perceived social support and emotion-focused coping is associated with higher SBP during provocation, β=.23, t=2.70, p<.01. Conclusion: Availability of social support is reassuring when coupled with the use of emotion-focused coping, and when the situation demands low coping resources (as during baseline). However, under conditions of stress where the demand for coping resources is high (e.g., during stress provocation), perceived social support and the use of emotion-focused coping does not help and may actually suggest an increase in CVR to stress. This may be related to the Chinese value of collectivism, which may manifest itself through an unwillingness to burden others with personal needs. Prospective studies demonstrate relations of subclinical depressive symptoms with enhanced risk for cardiovascular disease, yet little is known about underlying mechanisms. Depressive symptoms are also associated with unhealthy lifestyle behaviors and cardiovascular risk factors. We examined whether lifestyle factors mediated relations of depressive symptoms to cardiovascular risk factors in 205 healthy, community-dwelling older adults (55% male; mean age=66 years). Participants underwent a medical history, physical examination, blood chemistries, exercise treadmill testing with maximal oxygen consumption (Vo2max), an oral glucose tolerance test, clinical assessment of blood pressure and body mass index (BMI), completion of the Beck Depression Inventory (BDI), and assessment of smoking status and number of alcoholic drinks consumed per week. Primary outcome variables included systolic blood pressure, diastolic blood pressure, glucose levels at 0 and 120 minutes, waist circumference, triglycerides, and total, HDL, and LDL cholesterol. Potential mediators assessed were number of alcoholic drinks consumed per week, smoking status, Vo2max, and BMI. Multiple regression analyses adjusted for age, education, sex, race, and use of antihypertensives revealed a significant positive association between depression and triglyceride levels (b=24.2, p=.009), waist circumference (b=9.56, p<.001), and BMI (b=3.03, p=.001). Subsequent regression models testing for possible mediation indicated that the relation of BDI to triglycerides was mediated by BMI. Thus, in healthy older adults, depressive symptoms are associated with increased body mass, waist circumference, and triglyceride levels, and body mass mediates the relation of depressive symptoms to triglyceride levels. Obesity may be an important mechanism by which depressive symptoms influence cardiovascular risk in older adults. Patients with Chronic Obstructive Pulmonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF) display high levels of psychological distress which may be associated with increased mortality, lower functional status, and poor self-care behaviors. The purpose of this study was to characterize the psychosocial, cognitive, physical, and demographic profiles of patients with COPD and IPF with the goal of better understanding similarities and differences among patients with these pulmonary disorders. Patients with COPD (N=16; Female=5) and IPF (N=15; Female=5) were recruited from The Ohio State University outpatient pulmonary clinics. Participants completed three visits over the course of twelve months and at each session completed a series of questionnaires and cognitive function tests. At baseline and twelve months, participants completed pulmonary evaluations. IPF patients were significantly older (M=69.3) than COPD patients (M= 58.7) and had better pulmonary functioning (FEV1 % predicted= 75.7% in IPF vs. 44.2% in COPD) . All analyses of psychological functioning and cognitive performance were conducted controlling for age. COPD patients indicated significantly more symptoms of depression (p<.01; CES-D) and anxiety (p<.05; BAI) than did IPF patients. COPD patients also reported less social support (p<.01, PSSS). In addition, COPD patients indicated significantly poorer emotional quality of life, as reflected in the Mental Component Score of the SF-36. However, no differences were observed between COPD patients and IPF patients on the Physical Component Score of the SF-36 or in symptoms of breathlessness, sleep quality, or cognitive performance. Thus, although perceptions of physical quality of life and breathlessness are similar among COPD and IPF patients, patients with COPD indicate significantly greater symptoms of emotional distress and poorer emotional quality of life than patients with IPF. Heightened distress among patients with COPD is important to consider in treatment of patients. In addition, further evaluation of disease-related processes and biological differences between COPD and IPF patients is needed to understand mechanisms that may explain the observed differences. Objective: This study investigated a reactivity hypothesis and a vagal brake hypothesis of cardiovascular reactivity and recovery in the expressive and suppressive hostility behavior patterns of coronary artery disease (CAD) patients. Method: 82 CAD patients (age=61.50±10.53; 13.40% were female) participated in this experimental study. Participants were separated into four groups using the Chinese Hostility Inventory_ Short Form: high expressive hostility group, high suppressive hostility group, high expressive with high suppressive hostility group, and control group. Heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured in two-minute intervals under baseline, anger recall task (Time 1, Time 2, Time3), and recovery. Results: After controlling the baseline level to examine reactivity, the results indicated that significant difference between four groups in SBP, DBP and HR; as well an interaction existed among groups and SBP under the anger recall task. Post-hoc analyses indicated that the high expressive hostility group had higher SBP and DBP than the control group in Time 2; the high suppressive hostility group had higher SBP than the control group in Time 3. After controlling the anger level to examine recovery, an interaction existed among groups and SBP, DBP and HR. Conclusion: This study verified the reactivity hypothesis in the expressive hostility group who had peak SBP and DBP reactivity in the beginning of the anger recall task; however, the suppressive hostility group demonstrated peak SBP reactivity at the end of the anger recall task. This study also extended Proges's vagal brake hypothesis in recovery. Hostility behavior patterns caused different cardiovascular reactivity and recovery that regulated by autonomic nervous system. These reactivity and recovery may predict different psychopathological mechanisms or prognosis pathways in CAD patients. Heart rate variability(HRV) has been related to cardiac mortality and morbidity in cardiac patients. This research is to study whether a 8-week course of interventional program could mediate ANS function in cardiac patients. Participants(N=39)were randomly assigned to either treatment group consist of eight sessions of cognitive behavior group program, psycho education, breathing retraining and HRV biofeedback(Stress Eraser). The ANS function (SNS) were measured pre-(week 0) and post-(week 8) sessions. 1 Graduate School of Human Sciences, WASEDA University, Tokorozawa, Japan; 2 Faculty of Human Sciences, WASEDA University, Tokorozawa, Japan; 3 National Center of Neurology and Psychiatry, Kodaira, Japan and 4 National Cerebral and Cardiovascular Center Hospital, Suita, Japan.