More specifically, in DpAV4, ORF90 encodes a protein of 925 amino acid residues that is 40% similar from position 140 to 925 to a protein of 972 amino acid residues encoded by the ORF1 contained in the segment C20 in the GfIV genome (Fig. 2) . These two proteins can therefore be considered putative orthologs. The 480 C-terminal residues of this DpAV4 protein are also 42% similar to the Cterminal domain of the protein homologs encoded by the ORF1 of the D1 and D4 GfIV segments, 36% similar to the N-terminal and the C-terminal domains of the protein encoded by the ORFs 184R and 128L of the iridovirus CIV and LCDV, and 30% similar with those encoded by ORFs 119, 99 and 78 in the ascovirus genomes of HvAV3e, SfAV1a and TnAV2c, respectively. Overall, this indicates that this DpAV4 protein is more closely related to that of GfIV than to those found in other ascovirus and iridovirus genomes currently available in databases. ORF091 encodes a protein of 161 amino acid residues similar only with the C-terminal domain of three proteins encoded by the ORFs 1, 1 and 3, contained, respectively, in GfIV segments D1, D4 and D3. In contrast, ORF93 is closer to iridovirus and ascovirus genes than to GfIV genes. This protein of 849 amino acid residues is 43% similar over all its length to CIV ORF184R orthologs in all iridoviral and ascoviral genomes and is only 36% similar over 350 amino acid residues to the C-terminal domain of the GfIV protein homologs encoded by the ORF1, 2, 1, 1, 1 and 1 in, respectively, the C20, C21, D1, D2, D3 and D4 segments of this virus.