Several studies remark the importance of their protective effects for their principle antioxidants effects useful because it may help to prevent carcinogenicity-associated proliferative processes, but there are not recent publication about their toxicity or their side effects derived by their cronic or acute use. Anyway, if it presents, the side effects are poor (i.e., Glycyrrizin can induce hypokalemia, sodium retention, increase in body weight, and elevated blood pressure) [177] . Finally, hepatic damage from conventional drugs is widely acknowledged and most physicians are well aware of them. It is important to remember that acute and/or chronic liver damage occurred after ingestion of some Chinese herbs, herbals that contain pyrrolizidine alkaloids, germander, greater celandine, kava, atractylis gummifera, callilepsis laureola, senna alkaloids, chaparral, and many others. Several herbals have been identified as a cause of acute and chronic hepatitis, cholestasis, drug-induced autoimmunity, vascular lesions, and evenhepatic failure [79] ( Table 1 ).