Macropinocytosis has been identified as a major entry pathway of EBOV by research using the morphologically more relevant VLPs and live EBOV [174] [175] [176] [177] . Although none of these analyses examined the role of this pathway during MARV entry, it remains an intriguing possibility given the cholesterol-dependence and large size of macropinocytotic vesicles (up to 3-5 µm) [178] .