Similarly, another individual-based stochastic simulation model in Chicago evaluating the effects of antiviral treatment and prophylaxis, quarantine, isolation, school closure, community and workplace social distancing showed that social distancing alone may reduce overall AR by 60% for pandemic Ro of 1.9 but combination antiviral treatment and prophylaxis, quarantine, social distancing, and school closure could reduce overall AR by more than 90% for similar pandemic Ro of 1.9 [17] .