From 2294 PMIDs for which at least one protein-protein interaction was defined, database curation led to the validation of 2261 redundant interactions found in 789 papers, corresponding to 1374 confirmed non-redundant proteinprotein interactions (Supplementary Table 2 ). Strikingly, our experts confirmed 20% of BIND and GENERIF (HIV) against 90-95% for MINT and INTACT data.