Comparison among healthy controls and disease categories showed no difference in the levels of IFNc, IL12p70 and IL2RA were significantly lower in mild cases and higher in critically ill patients ( Table 2 ). All other molecules showed significantly higher levels in both patient categories. The overall pattern reflects pandemic-H1N1-09 influenza infection. The disease severity correlated with significant increase in IL1RA, IL2, IL6, CCL3, CCL4 and IL10 levels in critically ill patients.