There were some limitations with regards to this study. First, the relatively small sample size of this study might prevent some of the detected associations from being statistically significant. Second, our study results need to be validated across different populations. Since the incidence of KD in Asian populations is much greater than among Caucasians [1] , the host's genetic background must be considered in the study of KD. In our control group, the frequency of the −336G DC-SIGN gene allele was 3.5%. This result agreed with previous reports showing very low −336G DC-SIGN gene allelic frequency in Asians [33, 34] . The highest −336G allelic frequency was found in African populations (35-48%), next in Caucasian populations (20%), and the lowest was observed in Asians [8, 33] .