There were a total of 37 cases of combined FV and FVIII deficiency diagnosed during this time. There were 21 (57%) female and 16 (43%) male patients, with a mean age of 17 years (range: 1-49). Twenty-eight (76%) out of 37 cases were born of consanguineous marriages. A family history of bleeding was present in 14 (38%) cases. Nineteen patients (51%) were symptomatic prior to 5 years of age. The mean level of FV was 12.5% (range: 5-31), and the mean level of FVIII was 8.8% (range: 1227). In 11 out of 37 (30%) patients both FV and FVIII levels were 10% or lower. Seven out of 37 (19%) patients had both factor levels more than 10%.