The analysis using g:Profiler largely coincides with the analysis using GATHER, however, it retrieves 12 genes associated with the M phase of mitotic cell cycle, namely: AURKA and AURKB [227, 228, 229] , BUB1 [230, 231] , CDCA5A/Sororin/p35 [232] , CDC7 [233, 234] , CHEK1 [235] , KIF23/MKLP-1 [227, 236, 237] , MAP9/ASAP [238, 239] , NCAPD3, NCAPG2 [240] , NEK6 [241, 242, 243, 244] , PLK1 [147, 245, 246] , PTTG1/Securin [247] , SHC1/p66 [248, 249, 250] (discussed in the context of SHC4 signalling), and TFDP1/DP-1 [251] . These are a significant finding by g:Profiler (p-value = 4.03E-07).