Reporter assays have been widely used in biological research [1] [2] [3] . Such assays are a powerful means of investigating the signaling pathways involved in various biological functions induced by the activation of specific transcription factors. The reporter construct usually consists of a promoter (enhancer) that drives the transcription of a gene that is easily detected by its activity or expression in the assay system. The promoter region binds transcription factors that are activated in response to the stimulation of an upstream, receptor-mediated or receptor-independent signaling cascade. Binding of the transcription factor to the promoter results in the induction of reporter gene (and subsequent reporter protein) expression in response to signaling pathway activation by external stimuli, including drug candidates. It is important that the exogenous protein encoded by the reporter gene has unique enzymatic activity or another property that distinguishes it from endogenous proteins [4] .