Each realization is associated with a unique set of parameter values or alternatively is associated with a repeated set of parameter values. In the last situation, the results are referred to as a run replicate. Each model run produced by a specific model version is housed in the results data warehouse and consists of information that is part of the experiment. Fig. 2 defines the interconnections between the entities. A study is either linked to a published manuscript that defines project aims and study results or to a document that describes an MIDAS study that is part of a larger MIDAS project effort to examine specific hypotheses about disease spread and containment. For example, the DHHS project examined the problem of whether influenza could be stopped at its source (i.e., South East [SE] Asia), and if so, what methods of containment are important. Two studies from this project are part of the MREP: the Emory SE Asia Study and the Imperial SE Asia Study.