In order to further assess the consistency of altered gene expression across the studies we annotated the list of commonality differentially expressed genes to include studies published to the end of 2006 as well as our currently unpublished SAGE data. Comparisons were performed using all available published lists as well as accessing complete gene lists made available through online downloads. Differences in epilepsy models and global expression profiling platforms were also recorded. There were 72 genes reported to be regulated during epileptogenesis in two or more studies. Thirty-nine genes demonstrated a consistent direction of change with 15 showing conflicting results. The direction of regulation could not be ascertained from the available literature in 20 genes. No genes were reported regulated in more than five papers with the majority (50) only regulated in two papers. The two genes consistently regulated in five reports were the rather ubiquitous glial fibrillary acidic protein and the S100related protein (Table 3 ).