After observing that Figure 14 shows a correlation of Gleason pattern score with Normalized Shannon Entropy, we asked ourselves: 'which are the genes that most positively and negatively correlate with the transitions of Normalized Shannon Entropy?' We have plotted Spearman versus Pearson correlation values of probe expressions to attempt to find those that best correlate, either positively or negatively, with the Normalized Shannon Entropy values of the samples. The results have revealed some of the most relevant biomarkers of progression, and some unexpected newcomers. Figure 16 shows the Pearson and Spearman correlations of all the 13,188 probes in the dataset with the Normalized Shannon Entropy values of the samples. We have highlighted some particular genes that are discussed below.