Among several potential chromatin related functions, we chose to study epigenetic regulation and chromatin remodeling during cellular differentiation in more depth. Three important themes emerge from the shift in the expression of several known, classifiable proteins (Fig. 3C) . First, the data set contains histone modifying complexes such as Sin3A and SUDS3. Second group of proteins are the components of chromatin remodeling complexes including BAZ1B, SMARCC1 and CHD7. They are thought to regulate chromatin structures using ATPase activity. The third is a group of chromatin associating proteins, such that RB1, MCM2, TRIM24, HMGA1 and RCC1. They are involved in diverse functions such as transcriptional control, DNA replication and chromosome condensation.