Other TNF-related genes have been identified in the Zhikong scallop, such as a TNFR homologue [78] and a tumor necrosis factor receptor-associated factor 6 (TRAF6), which is a key signaling adaptor molecule common to the TNFR superfamily and to the IL-1R/TLR family [79] . Figure 7 shows that several components of the TLR signaling pathway that are present in our transcriptomic sequences (MyD88, IRAK4, TRAF-3 and -6, TRAM, BTK, RAC-1, PI3K, AKT, BTK and TANK).