Objective: A rather rare disease, micropneumatosis describes the findings of cyst-like cavities devoid of lining epithelium in the gastrointestinal wall. Micropneumatosis is often secondary to intestinal bacterial infection or mechanical factors. This study evaluates the incidence of micropneumatosis in our institute. Method: We analyzed all cases of micropneumatosis obtained in our institute between 2001 and 2011. Available data were retrieved from patients' records. Results: Out of 300.000 specimens obtained between 2001 and 2011, 71 cases (0.02 %) presented with micropneumatosis (37 female, 34 male; mean age 61 years, age range 18 to 85 years). Most common site was the colon (32 cases), followed by stomach (30), small intestine (8) and greater omentum (1). Conclusion: Micropneumatosis represents a rare but harmless diagnosis in gastrointestinal specimen. Due to the histological picture, which may be confused with dilated lymphatic vessels, submucosal lipomas, and, to the untrained eye, even with signet ring cell carcinoma, incidence may even be higher. In unclear cases, where there seems to be a endothelial layer, immunohistochemistry may be necessary to confirm diagnosis of micropneumatosis. This study shows that micropneumatosis should be considered in differential diagnosis in every age and sex.