To further understand the pathogenesis of rZH501-M847-G and rZH501-M847-A, we performed histopathological and IHC analyses of various organs of mice inoculated i.p. with 10 5 PFU of rZH501-M847-G, rZH501-M847-A, ZH501 or a mixture of 10 5 PFU of rZH501-M847-G and the same titer of rZH501-M847-A at various times p.i. (Figs. 6 and S2).