Finally, having established that DetectiV compares favorably with previously published software, we have validated the DetectiV software by applying it to a second dataset. The data used were downloaded from the GEO [14] , accession number GSE8746. The array platform for this data is GEO accession GPL5725, and consists of 5,824 oligos representing over 100 viral families, species and subtypes. The dataset itself consists of 12 arrays, 4 hybridized with RNA from cell cultured footand-mouth disease virus (FMDV) type O, 3 hybridized with RNA from FMDV type A, 1 hybridized with RNA from a sheep infected with FMDV type O, and 4 hybridized with cell-cultured avian infectious bronchitis virus (IBV). Analysis using DetectiV was carried out as described above.