With this information, and related empirical supporting information from other legume plants, it was hypothesised that T. esculentum bean and tuber extracts can inhibit RV infection. The proposed mechanisms of antiviral effects of T. esculentum are summarised in Figure 1 . It was herein projected that extracts from T. esculentum beans and tubers can be included in various medicine mixtures or whole beans and tubers be used as functional foods, with the aim to combat diarrhoea caused by RV.