Overall architecture of MIMOX Figure 1 Overall architecture of MIMOX. MIMOX has two sections. The first section has 3 perl scripts. The script mimosa.pl aligns a set of mimotope sequences powered by ClustalW. The script jalviews.pl wraps JalView to view and manage the alignment. The script mimocs.pl derives a consensus sequence from the alignment. The second section also has 3 perl scripts. The script mimox.pl maps the user supplied sequence on to the given antigen structure and utilizes NACCESS to calculate the accessibility. The script parsa.pl displays the detailed accessibility information of each mapping result. The script jmol.pl wraps Jmol to view the mapping result interactively on the antigen structure. Thus a consensus sequence is suggested by the program. The script also creates a 3D bar figure based on the statistical analysis above, where the X axis represents the 20 amino acid types and gap type, Y axis is the frequency and Z axis stands for the position of the aligned sequences (Shown in Figure 2 ).