Supporting Information Figure S1 . The distributions of R 0 estimates from fitting curves to simulated epidemic trajectories generated from biting behaviour described by a negative binomial distribution (black) with mean and variance equal to observed biting behaviour or by a poisson distribution (red) with the same mean. The range of R 0 estimates from simulations spans the range of estimates from compiled outbreak data from around the world ( collection and analysis, decision to publish, or preparation of the manuscript. Detection of genetically modified organisms (GMOs) using isothermal amplification of target DNA sequences BACKGROUND: The most common method of GMO detection is based upon the amplification of GMO-specific DNA amplicons using the polymerase chain reaction (PCR). Here we have applied the loop-mediated isothermal amplification (LAMP) method to amplify GMO-related DNA sequences, 'internal' commonly-used motifs for controlling transgene expression and event-specific (plant-transgene) junctions. RESULTS: We have tested the specificity and sensitivity of the technique for use in GMO studies. Results show that detection of 0.01% GMO in equivalent background DNA was possible and dilutions of template suggest that detection from single copies of the template may be possible using LAMP. CONCLUSION: This work shows that GMO detection can be carried out using LAMP for routine screening as well as for specific events detection. Moreover, the sensitivity and ability to amplify targets, even with a high background of DNA, here demonstrated, highlights the advantages of this isothermal amplification when applied for GMO detection. The ability to detect the presence of GMO is pivotal for consumers to be able to exercise their lifestyle choice of whether to consume, or not, food containing GMOs. Though the detection and quantification of GMO proteins using immunoassay has been reported [1] , denaturation of the protein during processing makes the method unsuitable for GMO testing and quantification of food. The durability of DNA makes it a better substrate for testing and its amplification by PCR is the method of choice, as recommended by the EC (2004/787), for detection and quantification of GMO in samples.