and n A , n C , n G , n T are the instantaneous values of the numbers of a, c, g, t present up to the particular position (x,y) on the sequence, starting the count from the beginning, i.e. the 59-end, of the sequence. These are our empirical equations connecting the intrapurine (x) and intra-pyrimidine (y) numbers obtained from the observations of the patterns on the 2D graphical plots. While the majority of the plots shown are well-represented by such polynomials of the second degree, the fits could be improved in some instances by fitting higher degree polynomials as mentioned earlier; e.g., in the case of the human beta-globin gene a polynomial of the third degree yields better statistics (R 2 = 0.94) than the second degree (R 2 = 0.81), for the human delta globin gene the statistics for the quadratic and cubic fits are R 2 = 0.87 and R 2 = 0.98, respectively. We, however, consider the second degree form for now for conformity without excessive loss of statistical significance.