Conclusions: As this was an African-American study sample, desire to support research as a primary participation reason is noteworthy. Contact by study staff as a major reason for participation is also significant. Importantly, respondents' desire to maintain their health was another principal reason cited for participation. These findings provide insight into reasons why African-American patients decide to participate in prevention research. We will add to these data through the analysis of responses from 896 individuals targeted for recruitment. We examined barriers to colorectal cancer (CRC) screening among urban and rural Pennsylvania Latino/Hispanic adults. A total of 82 Latinos/Hispanics engaged in one of eight focus groups stratified by sex and geography offered; and completed a 25-item survey eliciting their demographic information and CRC cancer screening behaviors. After the focus group, participants viewed a sevenminute American Cancer Society's published Spanish DVD entitled, "Get Tested for CRC. Here's How" and reassemble to answer questions about their preference and acceptability of the CRC screening options. Focus group data were audio taped, transcribed and grouped into thematic units using content analysis. We found substantial barriers by sex and geography, including urban residents received screenings during annual check-ups, while rural residents received screenings in response to symptoms. Of the 57 total barriers reported, four barriers were unique to urban Latino/Hispanic residents; and 13 barriers were unique to rural Latino/Hispanic residents. Low levels of health literacy, knowledge and awareness of CRC risk and screening were reported barriers across groups. The family unit and strong social support were also factors reported as influencing their CRC screening behavior. Participants identified barriers to CRC screening that fit into five categories: (a) physical environment, (b) structural factors, (c) sociocultural factors, (d) individual factors, and (e) physician-related barriers. Latino/Hispanic participants also identified potential strategies to overcome each reported barrier. These finding suggest that a targeted CRC screening intervention utilizing a physician-recommended home fecal immunochemical test with instructions is preferred among Latino/Hispanics over a non-targeted approach. African Americans are more likely to be diagnosed with, and to die from, colorectal cancer (CRC) than any other group. Approximately half of CRC deaths could be prevented if screening were consistently implemented. The Transtheoretical Model postulates that behavior change occurs over time with people moving through stages of readiness to adopt the behavior. The aims of this study were to: 1) examine distribution across stages of readiness to screen for CRC among African American primary care patients; and 2) determine whether demographic and health belief variables predict stage of readiness to screen. Baseline data were collected via telephone interviews from 311 patients who were due for screening and enrolled in a RCT testing efficacy of a computer-based intervention designed to increase CRC screening. Ordinal logistic regression models were used to examine demographic variables and Health Belief Model constructs (perceived risk, benefits, barriers and self-efficacy) as predictors of stage of readiness to screen for CRC. The sample was 56% male and a mean age of 58 years. For FOBT, 51.8% of patients were precontemplators, 37% were contemplators, and 11.3% were in preparation. oral health problems and their corresponding clinical signs (67 in total) were identified. The aim of this study is to present the content validity of the tool. Method. A dentist and three general practitioners in palliative care in Quebec (Canada) were invited to evaluate the relevance and sufficiency of each of the clinical signs identified. The relative importance of clinical signs was also assessed for certain oral health problems. As suggested by Polit, Tatano Beck and Owen (2007), an I-CVI of at least .75 was used to conclude about the relevance of a given clinical sign.