The Servers and the Services The four servers described here, collectively referred to as the SEED servers, currently support 181 methods that can be invoked to extract data and services (Fig. 1) . The server code resides at the location of the SEED data. Users download a distribution with their choice of runtime environment that they may use to write programs to access SEED data or perform a number of common bioinformatics tasks using a supplied set of preprogrammed scripts. Currently, Perl and Java integrations are supported. The following subsections describe the four servers in more detail.