Results: The miR-128-1 was more abundant in NB against to miR-124 and -221 (p<0.05). MiR-124 and miR-128-1 were significantly down-regulated in all grades compared to NB (p<0.05) but in grade IV was more decreased: 8000-and 1200-fold, respectively. In patients with recurrent tumor, the expression of miR-221 was lower (p<0.002). Live patients expressed high levels of miR-128 (p< 0.02) and miR-221 (p < 0.0026) against deceased.