[Results] Linear regression analysis was performed in which CES-D scores served as a dependent variable, and subjective stress and gene polymorphisms as independent variables: consequently, SS carriers of the 5-HTTLPR gene showed significant higher depressive symptoms in comparison with LL/SL carriers, even after controlling for confounders (F=27.6, standardized beta=2.2, p<0.05). Regression analysis also confirmed some other gene polymorphisms significantly associated with depressive symptoms.