where k 2 is a coefficient. The formula means choosing t+a 1 from × to construct the first type of cell, and choosing a 2 from x-t-a 1 to construct the second cell, and so on. The possibilities for every protein molecule in all cell types are t, and the numbers of free protein molecules are proportional to the diversities of cellular proteome. As the calculated value of Σlog(C) is actually quite small and can be negligible, the information to produce diverse differentiated cells is: