1. To learn about the general brain cortical anatomy. 2. To be able to identify the most important cortical anatomy involved in the language system and its imaging representation. 3. To be able to recognise the most import white matter tracts involved in the language system and its imaging representation. 4. To get a glimpse into the relevant anatomical and clinical insights coming from MR microscopy. MRI is an imaging technique that is particularly sensitive to haemorrhages in the brain. Apart from large haematomas and recent subarachnoid haemorrhages, that are also visible on CT, using MRI minute haemorrhages (microbleeds) can be detected within the brain and subtle remote haemorrhages in the subarachnoid space (superficial siderosis) can be detected. In addition, MRI allows for assessment of the age of cerebral haemorrhages, based on signal characteristics. The location of cerebral haemorrhages allows for an estimation of the underlying pathology. For example, haematomas with a lobar distribution are suggestive of cerebral amyloid angiopathy, those located in the basal ganglia in a patient with hypertension are suggestive of hypertensive microangiopathy, and blood in the subarachnoid space is suggestive of a ruptured aneurysm. A comprehensive MRI protocol (comprising T2*-weighted images, post-gadolinium images, and MRA techniques) also allows Complexity and heterogeneity of the lymphomas and especially the DLBCL (Diffuse large B-cell lymphoma) have been demonstrated over the past 10 years, first by the most recent WHO classification that includes no less than 50 different subentities, and second by the gene expression profiling analyses leading to a molecular classification in the most common form of adult non Hodgkin's lymphoma, the DLBCL entity. The prognosis has been demonstrated to be variable according to the morphological, immunophenotypic and molecular classification. The therapeutic approach is different according to the classification. So the importance of the material obtained by different techniques is crucial: excisional lymph node biopsy or core needle biopsy (which is increasingly replacing chirurgical techniques) must be properly used in order to obtain a good morphology and frozen material dedicated to molecular analysis. Learning Objectives: