To further evaluate whether the strongest mAb DB32-6 could broadly neutralize the diverse DENV-2 strains, we infected BHK-21 cells with four different DENV-2 Southeast Asian genotype strains, 16681, NGC, PL046 and Malaysia 07587. Remarkably, mAb DB32-6 exhibited effective neutralization against various DENV-2 strains ( Figure S3 ).