According to the definition made by ACCP/SCCM Consensus Conference in 1992, sepsis is known to be an early syndrome that may progress to a pathologic state manifested by hypotension and hypoperfusion known as septic shock. LPS has been associated with sepsis and the high mortality rate seen in septic shock (5) . However, it is the exaggerated host response to the systemic release of endotoxin that accounts for septic shock from Gram-negative bacteria (23) .