IFN-H transcript levels were up-regulated 2.22 fold by DgB virions and 2.06 fold (p = 0.01) by DgD virions, again with a high degree of statistical significance. Inoculation with virus particles lacking gH led to a 21.07 fold change (p = 0.44) in IFN-H expression when compared to mock-infected cultures. All three entry-defective mutants were unable to modulate the expression of IFN-l above the arbitrary two-fold threshold.