Statistical analysis was performed using the software package SPSS 18 (IBM). An independent sample t-test was employed to compare the strains at different time points. Childhood Tuberculosis Presenting with Haemophagocytic Syndrome Haemophagocytic syndrome is a life threatening complication of systemic infection resulting from an exaggerated immune response to a triggering agent. Prompt recognition and treatment of this disorder can abrogate otherwise high fatality associated with this disorder. A 2 year old girl presented with acute enteritis, developed prolonged fever and organomegaly complicated by multi-organ failure. She fulfilled the diagnostic criteria for haemophagocytic lymphohistiocytosis including bone marrow evidence of haemophagocytosis. In addition she had serological evidence of tubercular infection as well as a positive family history of tuberculosis. She responded rapidly to immunosuppressive therapy and anti-tubercular therapy. Our case illustrates the association of haemophagocytic syndrome with tuberculosis as well as the favourable response obtained with prompt diagnosis and treatment. Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder caused by unrestrained proliferation and activity of the monocyte-macrophage system with phagocytosis of the mature and immature formed blood cells, release of inflammatory mediators, coagulopathy and often multiorgan failure. It has been described in all age groups, especially in the paediatric-adolescent population. Management usually consists of immunosuppressive agents along with treatment of the underlying condition. The HLH 2004 protocol consists of repeated cycles of cyclosporine-etoposidedexamethasone; however, sustained responses are rare, especially in familial HLH, and most patients eventually relapse [1] . Bone marrow transplant remains the only effective therapy for refractory cases but entails high procedure related mortality.