The incubation period of H5N1 infection in humans has usually ranged from 2-5 days, though clinical features have appeared even up to 8-17 days after exposure . Almost all patients present with high grade fever (>38°C). Cough and dyspnea are seen commonly (about 90%). Sore throat is seen in around half the patients with rhinitis and upper respiratory symptoms being less common. Headache, myalgia and weakness have also been reported. Gastrointestinal symptoms such as diarrhea, vomiting and abdominal pain may also be present. Watery diarrhea may precede respiratory symptoms by a week [9] [10] [11] . One case with fever, diarrhea, seizure and coma has been reported from Vietnam leading to a clinical diagnosis of encephalitis. H5N1 was detected from CSF, serum, throat and fecal samples [12] . Conjunctivitis is also described occasionally [13, 14] .