When we compared between three groups of patients (1st group: both FV and FVIII <10%; 2nd group: both FV and FVIII levels >10%; 3rd group: either FV or FVIII <10%) there was no difference between different bleeding symptoms. The same has also been reported from both the series from Iran [7, 9] . When we compared between two groups of patients (1st group: both FV and FVIII <5%; 2nd group: both FV and FVIII >5%), there were no differences in the bleeding symptoms observed. This shows that presence of two defects do not make the severity of bleeding greater than that expected in patients with single coagulation defects of similar degrees.