The ultimate objective of controlling rabies is the prevention of human deaths. Human rabies mortality can be reduced through ensuring administration of vaccine and immunoglobulin (postexposure prophylaxis, PEP), following extensive washing of the wound, to all bite victims from infected animals. However, these life-saving biologics are often not accessible or affordable to the populations most at risk [14] . Furthermore, interventions focusing solely on rabies prevention in humans have no impacts on reducing infection in maintenance hosts, hence on achieving rabies elimination from an area-the so-called "incurable wound." For centuries, rabies control in reservoir hosts has constituted an essential measure to decrease the burden of human mortality. Effective vaccines for animals are available, and most developed countries have eliminated canine rabies [15] [16] [17] , responsible for the vast majority (99.9%) of all human cases [18] , by preventing the disease in dogs. However, lack of effective canine rabies prevention and control programs in poorly resourced countries continues to cause tens of thousands of human deaths every year [18] . In canine rabies endemic countries, rabies is a recurrent public health issue and also represents a threat to rabies-free areas through the movement of infected dogs-as was the case in Bali, where rabies was introduced recently [19, 20] . Despite the availability of modern and efficient prophylaxis tools for humans and animals, on average, rabies still kills one person every 10 minutes, with the highest burden of mortality in Africa and Asia and most of the deaths occurring in children less than 15 years old [18] .