To illustrate the use of our methodology, we present a sample H5N1 outbreak scenario including four counties in Fla, USA: Hillsborough, Miami Dade, Duval, and Leon, with populations of 1.0, 2.2, 0.8, and 0.25 million people, respectively. A basic unit of time for population and disease dynamics models was taken to be Δt = 1 hour. Regional simulations were run for a period (up to 180 days) until the daily infection rate approached near zero (see Section 3.3). Below, we present the details on selecting model parameter values. Most of the testbed data can be found in the supplement [77] .