We found a total of 785 protein peaks in the sera of all samples (Table 1 ). The most represented pH fraction was F6 (n = 381), followed by F4 (n = 223), and F1 (n = 181). On surface CM10 we identified 317 peaks, on IMAC30 302 peaks, and on H50 166 peaks. Furthermore, a much higher number of peaks (n = 512) was found on low mass range (1-20 kDa) compared to the high (n = 273; 20-200 kDa).