These results clearly show that the NINA heater can incubate isothermal reactions predictably and precisely with no electricity and without any form of closed-loop control. We also demonstrate that it can be used for LAMP assays, with no discernable difference when compared to two reference heaters, the GeneAmpH 9600 and the ESE-Quant Tube Scanner. There is a bias between the NINA heater and the ESE-Quant (NINA higher), but this is not a significant finding considering we are comparing FIU without any assay calibration. This bias would be easily removed by applying a standard curve. Although we did not intend to rigorously qualify the LAMP assay for malaria here, these results suggest that a quantitative assay with a clinically significant lower limit of detection and three decade dynamic range might be possible with further development of the protocol. Planned work will comprehensively compare incubation of several isothermal assays with the NINA heater to incubation with conventional, electrically-powered instruments by many metricssensitivity, specificity, accuracy, precision, and other standard figures of merit must all be assessed before equivalence can be rigorously inferred. However, these prelimary results are very encouraging.