Total (Investigated probesets) 21097 16213 the originally false transcripts during the update of sequence information, as they may lead to the absence of the transcript targets of some probesets. Similarly, there are a large number of one-to-one probesets in the socalled Affy others group, 1,206 out of 2,619 for MOE430A_2 and 476 out of 1,555 for HG-U133A. These probesets, however, might not be really one-to-one mapping to the identified transcript targets, as our strategy was based on the premise that most probesets were specific for certain genes, and our blast was limited to the candidate transcripts associated with the probesets, but not the entire transcript pool.