Co-morbidities were present in 15 (25.4%) patients: alcoholic hepatic disease, diabetes mellitus and ischemic cardiac disease in five patients; sickle cell anaemia, nephrolithiasis, Still disease and hepatitis C were observed in one patient each. One had been bone marrow transplanted seven years before and was asymptomatic, with no immunomodulatory therapy. An HIV primary infection was diagnosed simultaneously with malaria in one patient, being all other patients HIV negative. Some patients presented more than one comorbidity.