Diversity among respiratory HBoV1 and enteric HBoV2-4. We compared the intraspecies diversity of HBoV1 with that of HBoV2 by use of the partial VP1 sequence data generated with the pan-bocavirus PCR primers available for the greatest number of HBoV2, 3, 4 variants ( Figure 4A and 4B) . A very low average pair-wise difference was seen for HBoV1 collected worldwide ( Figure 4A ). HBoV2, including both genotypes, was more diversified than HBoV1, although HBoV2B alone showed a low level of diversity comparable to that of HBoV1 (HBoV2B generated the large low divergence peak in Figure 4A ). The homogeneity of HBoV1 and HBoV2B can also be visualized in the small branch lengths in Figure 1 . When the pair-wise dis- tances of all the enteric (non-HBoV1) sequences were plotted ( Figure 4C ), the distribution was much larger than that for HBoV1. The low level of intraspecies diversity of HBoV1 relative to the other species is also reflected in Table 2 .