The copy number variation results for known ratios of 1, 1.5, 2, 2.5, 3 and 3.5 are shown in Figure 8 . Materials and methods for this experiment are discussed in next section. As the number of panels P increases, then the number of chambers C = 765 Pincreases and therefore the estimation of the ratio becomes more accurate as well as the confidence interval shrinks. When only 1 panel is used, there is significant overlap between 95% confidence intervals of certain ratios e.g. between ratio 2 and 2.5. There is no overlap when 3 or more panels are used. In all cases the known ratio lies within the computed 95% confidence interval. Note that using mathematical analysis one can find optimal numbers of positive chambers for each ratio which give smallest confidence intervals and which will therefore improve the results.