Blood transcriptional profi les have been generated in the context of many other autoimmune diseases. Indeed, the range of autoimmune/autoinfl ammatory diseases that have been investigated encompasses SLE [20, 21, 48, 49] , juvenile idiopathic arthritis [16, [50] [51] [52] [53] , multiple sclerosis [54, 55] , rheumatoid arthritis [56] [57] [58] [59] , Sjogren's syndrome [60] , diabetes [61, 62] , infl ammatory bowel disease [63] , psoriasis and psoriatic arthritis [45, 47] , infl ammatory myopathies [64, 65] , scleroderma [66, 67] , vasculitis [68] and anti-phospholipid syndrome [69] . Th e body of work produced that focuses on blood transcript profi ling in the context of autoimmune diseases has been covered at length in a recent review [70] .