As HBoV has been first identified in respiratory samples, it has been suggested as a respiratory tract infection agent [1] . The majority of the following studies in fact detected HBoV in children with respiratory tract infections. Clinical symptoms mostly described in conjunction with an HBoV infection are wheezing, fever, bronchiolitis and pneumonia [28, 49, 36, 50] . Studies including asymptomatic controls showed that HBoV is also detectable in these controls but with a lower incidence [20, 58, 59] . For example, HBoV was detected in 17 % of children hospitalized because of respiratory infection, while only 5 % of the surveyed asymptomatic children were HBoV positive [58] . This supports the assumption that HBoV in fact could be assigned to the respiratory viruses.