OFP-03-007 Outcomes of neoadjuvant chemoradiation for rectal carcinoma G. Ozgun * , F. Oz Atalay, N. Ugras, O. Yerci * Uludag University, Dept. of Pathology, Bursa, Turkey Neoadjuvant radiation and chemoradiation is currently the treatment of choise for patients with locally or advanced carcinoma of the rectum. Patients treated with neoadjuvant chemoradiatheraphy with good clinical response and tumor regression present a controversial management dilemma. To assess the effects of chemoradiation on tumor regression and disease free survival, consecutive series of 27 patients receiving neoadjuvant chemotheraphy or chemoradiation and a control series of 32 patients without pretreatment were studied. The overall survivals and disease free survivals were compared in terms of variables such as tumor regression grade, stromal response in tumor bed, state of lymph node metastasis, and the localization of the tumor in between patients treated with chemoradiation and the control group. Neoadjuvant treatment is one of the treatment modalities in rectal carcinomas. We want to present our experience between 2005 and 2011 in our institution. Key words: Rectal carcinoma, neoadjuvant treatment, pathologic complete response OFP-03-008 Identification of Tissue Microvascular Invasion Biomarkers in Hepatocellular Carcinomas by MALDI Imaging Mass Spectrometry N. Poté * , T. Alexandrov, J. Le Faouder, S. Laouirem, J. Belghiti, J. M. Camadro, V. Paradis, P. Bedossa * Paris, France