Outcome measures include Clinical Comprehensive Effect, Hamilton depression scale (HAMD) scores, self-rating depression scale (SDS) scores, self-rating anxiety scale (SAS) scores, Hamilton Anxiety Scale (HAMA), scores, clinical global impression (CGI) scores, the scale for TCM syndrome and symptom differentiation (TCM-SSD) scores and so forth, the criteria "recover, significant effective, effective, or not effective" was also include in the outcome measurement. Duplicated publications reporting the same groups of participants were excluded.