The bottom panel of Figure 6 shows the relation between the optimal fractions of individuals taking antiviral drugs as a function of the antiviral efficacy for infectiousness. The antiviral efficacy for susceptibility is fixed at AVE S = 0.3. The picture in this panel is more complicated than in the top panel. In particular, eradication of the pathogen is not feasible if the antiviral efficacy for infectiousness drops below a critical value (AVE I ,0.51). If the antiviral efficacy for infectiousness is just above this critical value it still is the best strategy to drive the pathogen to extinction if one If, on the other hand, the antiviral efficacy for infectiousness is low (AVE I ,0.07) it is better not to take antiviral drugs at all (s Ã pop~0 ) as the benefit of taking antiviral drugs do not outweigh the cost. In this region of parameter space both optimal control rates are zero. In the intermediate parameter regime (0.07,AVE I ,0.51) it is not possible to achieve eradication, but it may nevertheless be wise to take antiviral drugs. In fact, taking the population perspective, it is always better to be (partially) protected by antiviral drugs than to be fully susceptible in this region of parameter space (i.e. s Ã pop ??), even though eradication is not possible.