Symptomatic patients should be isolated with strict respiratory isolation until treatment for at least 3 days [10] . The treatment of choice is streptomycin, alternatively doxycycline, gentamicin, ceftriaxone, chloramphenicol, or fluoroquinolones can be used. Treatment duration is for 10 days at a minimum. If exposed to aerosolized plague or to a patient with suspected pneumonic plague, prophylaxis with ciprofloxacin, doxycycline, tetracycline, or chloramphenicol should be given [42] .