For the JEV group the mean SSSV between positions 117-358 (start codon at position 97) was consistent with ALIDOT-predicted RNA structures JE2, JE3 and JE4 (Supplementary Figure S1A) (28) . However, the SL6-like structure for the JEV group was clearly predicted by STRUCTURE_DIST analysis (brown box in Supplementary Figure S1A ), in accordance with MFold and alignment analysis.