Bayesian time-scaled phylogeny of HPeV based on VP1 sequence analysis Figure 1 Bayesian time-scaled phylogeny of HPeV based on VP1 sequence analysis. Maximum clade credibility tree obtained with BEAST with a constant size coalescent prior showing lineage splitting events (nodes A-F) since the most recent common ancestor to the presently circulating HPeV types. The divergence times correspond to the mean posterior estimate of their ages (in years). For the TMRCA, the correspondent 95% Bayesian credible intervals are shown (median 1600). Time axis is shown in years and ranges from the TMRCA to the present year. Deeper and some subtype nodes with posterior probability of higher than 0.8 are pointed out. Each colour corresponds to a specific HPeV, as indicated in the box on the right. The dashed grey circle depicts the extent of genetic diversity of the sampled HPeV strains. HPeV-1-"Harris-like" strains (*) clustered separately from the contemporary HPeV-1.