Studies have reported HBoV DNA in 3%-19% of children with RTIs. Rates of detection tend to be higher in children <1 year of age (4, 10) . The incidence of HBoV infections also tends to be higher in samples from the lower respiratory tract, such as NPA or BAL (4.4%-19%) (2, 7, 9, 11, 13, 19, 21, 22) , than in nasal swabs (1%-6%) (10, 15, 16, 18) . The percentage of co-pathogens in our HBoV-positive children (71%) was comparable with those reported in the literature, with rates of co-infections ranging from 35% to 90% (2, 3, 7, (9) (10) (11) (20) (21) (22) . Moreover, coinfecting viruses detected in conjunction with HBoV in our population were similar to those described in other studies, i.e., hRSV, infl uenza A virus, and adenovirus (11, 23) .