The PRP next combined their knowledge, efforts, and resources to define specific strategies that would enable canine-rabies endemic countries to design their own national programs for preventing human rabies. Despite the availability of several guidelines and publications on various aspects of controlling rabies in dogs and preventing rabies in humans, it was realized that there was no integrated standard operating procedure or "Blueprint" bringing together all necessary aspects for a "One Health" approach to controlling rabies. Rabies is a zoonotic disease and, in order for interventions to be successful, control programs must incorporate an integrated, or One Health, approach including human and animal public health principles, diagnostics and surveillance, education and advocacy, anthropology, social mobilization and community outreach, research and development, and program implementation and evaluation as well as funding options. The need for such comprehensive strategies has been clearly identified following the successful adoption of this approach in Latin America leading to dramatic impacts on human and animal rabies cases [44] . The PRP was able to draw on global expertise to incorporate all of these aspects into a Blueprint for rabies prevention and control which is currently available online. [45] . As a next step, the PRP is focusing on combining their efforts to re-evaluate the global burden of rabies in order to establish the cost effectiveness of intervention strategies.