A total of 6 parameters(CD3 + , CD4 + , CD8 + , CD4 + /CD8 + , CD19 and CD16 + +56 + ) were measured in the 56 PE patients, and 53 had abnormalities in one or more parameters: 27 had abnormal CD3 + expression (decreased in 25 and increased in 2) ( Figure 8A ); 18 had aberrant CD4 + expression (decreased in 10 and increased in 8) ( Figure 8B) ; 26 had abnormal CD8 + expression(decreased in 25 and increased in 1) ( Figure  8C ); 30 had aberrant CD4 + /CD8 + ratio (decreased in 7 and increased in 23) ( Figure 8D ); 23 had abnormal NK CD16 + +56 + expression in 50 patients (decreased in 14 and increased in 9) ( Figure 8E ) and 17 had aberrant CD19 expression in 56 patients (decreased in 15 and increased in 2)( Figure 8F ); The CD8 + expression was decreased in 25 out of 56 patients(44.6%), the CD8 + and CD16 + +56 + expressions were decreased in 34 out of 56 patients(60.7%), and the CD8 + , CD16 + +56 + and CD19 expressions were decreased in 39 out of 56 patients(69.8%)( Figure 8G ). 