so-called normal appearing white matter. Dynamic susceptibility-weighted contrastenhanced perfusion MR imaging provides haemodynamic information that complements traditional structural MR imaging and is being increasingly used in clinical practice to diagnose, manage and understand brain tumours in the paediatric patient group. Clinical studies of today involve multidimensional high-resolution images containing a substantial amount of structural and functional information. The role of quantitative imaging and the parameters measured have become more and more important to evaluate severity of a disease, disease progression and response to therapy, to mention a few examples. Increasing number of different quantitative image analysis techniques that can be used both in adult and children have been described in the recent years. Different imaging analyses like region-of-interest analysis, intra-individual voxel-based analysis and inter-voxel based analysis are a few examples all with different limitations and drawbacks as will be discussed in this lecture. The role of different imaging analyses such as DTI tractography and perfusion MR and the use of quantitative measures of different parameters and their application in children will be presented. Pancreatic neoplasms have a very different prognosis and treatment. In order to illustrate the experiences of a multidisciplinary group at the University of Verona, the participants (surgeon, pathologist and radiologist) will discuss some of the issues that are critical in the diagnosis, differential diagnosis and management of pancreatic cancer patients. Session Objectives: 1. To understand the role of a multidisciplinary approach.