Paragraph 1: Santiago de Compostela, in Galicia, the centre of devotion to this Apostle, is neither the cradle nor the principal seat of the order. Two cities contend for the honour of having given it birth, León in the kingdom of that name, and Uclés in Castile. At that time (1157–1230) the royal dynasty was divided into two branches, the rivalry of which tended to obscure the beginnings of the order. The Knights of Santiago had possessions in each of the kingdoms, but Ferdinand II of León and Alfonso VIII of Castile, in bestowing them, set the condition that the seat of the order should be in their respective states. Hence arose long disputes which only ended in 1230 when Ferdinand III, the Saint, united both crowns. Thereafter, Uclés, in Cuenca Province, was regarded as the headquarters of the order; there the grand master habitually resided, aspirants passed their year of probation, and the rich archives of the order were preserved until united in 1869 with the "Archivo Histórico Nacional" of Madrid. The order received its first rule in 1171 from Cardinal Jacinto (later Pope Celestine III), then legate in Iberia of Pope Alexander III. This first Grand Master was Pedro Fernández de Castro, also known as Pedro Fernández de Fuentecalada, a soldier of King Ferdinand II and a former crusader.

Paragraph 2: "Kernkraft 400" has been sampled by various artists, including rapper The Game in the single "Red Nation". The song is used by the Boston Bruins and Milwaukee Admirals, who both play it at home games after a goal is scored. The Bruins have been using it ever since the song was originally released. The Toronto Maple Leafs used the song at home games after a goal was scored from 1999 to 2013. It grew in popularity within the hockey community during the 2011, 2013, and 2019 Stanley Cup Playoffs when the Bruins had three deep runs. The Pittsburgh Steelers have played this song pre-game kickoff since before 2010. The Seattle Mariners also play the song after a big hit or during rallies at T-Mobile Park. The Los Angeles Dodgers play the song after a home run. Penn State football has been using "Kernkraft 400" since as early as 2005. During the break in the song, fans chant "We Are Penn State." The song became a semi-official anthem for Welsh football fans during their country's qualification campaign for UEFA Euro 2016. This stems from an incident after their 0–0 draw with Belgium at Stade Roi Baudouin in Brussels, in which the travelling Welsh fans danced enthusiastically to the song being played over the stadium's public address system. As a result, the song was played before the return fixture at Cardiff City Stadium on 12 June 2015.

Paragraph 3: AGEP also differs from the other SCARs disorders in respect to the level of evidence supporting the underlying mechanism by which a drug or its metabolite stimulates CD8+ T or CD4+ T cells. Studies indicate that the mechanism by which a drug or its metabolites accomplishes this stimulation involves subverting the antigen presentation pathways of the innate immune system. A drug or metabolite covalently binds with a host protein to form a non-self, drug-related epitope. An antigen-presenting cell (APC) takes up these proteins; digests them into small peptides; places the peptides in a groove on the human leukocyte antigen (i.e. HLA) component of their major histocompatibility complex (i.e. MHC) (APC); and presents the MHC-associated peptides to the T-cell receptor on CD8+ T or CD4+ T cells. Those peptides expressing a drug-related, non-self epitope on their HLA-A, HLA-B, HLA-C, HLA-DM, HLA-DO, HLA-DP, HLA-DQ, or HLA-DR proteins may bind to a T-cell receptor to stimulate the receptor-bearing parent T cell to attack self tissues. Alternatively, a drug or metabolite may also stimulate T cells by inserting into the groove on a HLA protein to serve as a non-self epitope, bind outside of this groove to alter a HLA protein so that it forms a non-self epitope, or bypass the APC by binding directly to a T cell receptor. However, non-self epitopes must bind to specific HLA serotypes to stimulate T cells and the human population expresses some 13,000 different HLA serotypes while an individual expresses only a fraction of them. Since a SCARs-inducing drug or metabolite interacts with only one or a few HLA serotypes, their ability to induce SCARs is limited to those individuals who express HLA serotypes targeted by the drug or metabolite. Thus, only rare individuals are predisposed to develop SCARs in response to a particular drug on the basis of their expression of HLA serotypes. Studies have identified several HLA serotypes associated with development of DRESS syndrome, SJS, SJS/TEN, and TEN in response to various drugs which elici these disorders, developed tests to identify individuals who express these serotypes, and thereby determined that these individuals should avoid the offending drug. HLA serotypes associated with AGEP and specific drugs have not been identified. A study conducted in 1995 identified of HLA-B51, HLA-DR11, and HLA-DQ3 of unknown serotypes to be associated with development of AGEP but the results have not been confirmed, expanded to identify the serotypes involved, nor therefore useful in identifying individuals predisposed to develop AGEP in response to any drug. Similarly, a specific T cell receptor variant has been associated with the development of DRESS syndrome, SJS, SJS/TEN, and TEN but not AGEP.

Paragraph 4: In The Observer'''s issue of 18 July 1937, "Torquemada" (Edward Powys Mathers) said, "usually after reading a Poirot story the reviewer begins to scheme for space in which to deal with it adequately; but Dumb Witness, the least of all the Poirot books, does not have this effect on me, though my sincere admiration for Agatha Christie is almost notorious. Apart from a certain baldness of plot and crudeness of characterisation on which this author seemed to have outgrown years ago, and apart from the fact that her quite pleasing dog has no testimony to give either way concerning the real as opposed to the attempted murder, her latest book betrays two main defects. In the first place, on receiving a delayed letter from a dead old lady Poirot blindly follows a little grey hunch. In the second place, it is all very well for Hastings not to see the significance of the brooch in the mirror, but for Poirot to miss it for so long is almost an affront to the would-be worshipper. Still, better a bad Christie than a good average."The Scotsman of 5 July 1937 started off with: "In Agatha Christie's novel there is a minor question of construction which might be raised." The reviewer then went on to outline the set-up of the plot up to the point where Poirot receives Emily Arundell's letter and then said, "Why should the story not have begun at this point? M. Poirot reconstructs it from here and the reader would probably have got more enjoyment out of it if he had not had a hint of the position already. But the detection is good, and the reader has no ground for complaint, for the real clue is dangled before his eyes several times, and because it seems a normal feature of another phenomenon than poisoning that he tends to ignore it. For this Agatha Christie deserves full marks."

Paragraph 5: A major coup in her career was participating in the 1876 Centennial Exposition in Philadelphia. For this, she created a monumental 3,015-pound marble sculpture, The Death of Cleopatra, portraying the queen in the throes of death. This piece depicts the moment popularized by Shakespeare in Antony and Cleopatra, in which Cleopatra had allowed herself to be bitten by a poisonous asp following the loss of her crown.  Of the piece, J. S. Ingraham wrote that Cleopatra was "the most remarkable piece of sculpture in the American section" of the Exposition. Much of the viewing public was shocked by Lewis's frank portrayal of death, but the statue drew thousands of viewers nonetheless. Cleopatra was considered a woman of both sensuous beauty and demonic power, and her self-annihilation has been portrayed numerously in art, literature and cinema. In Death of Cleopatra, Edmonia Lewis added an innovative flair by portraying the Egyptian queen in a disheveled, inelegant manner, a departure from the refined, composed Victorian approach of representing death. Considering Lewis's interest in emancipation imagery as seen in her work Forever Free, it is not surprising that Lewis eliminated Cleopatra's usual companion figures of loyal slaves from her work.  Lewis's The Death of Cleopatra may have been a response to the culture of the Centennial Exposition, which celebrated one hundred years of the United States being built around the principles of liberty and freedom, a celebration of unity despite centuries of slavery, the recent Civil War, and the failing attempts and efforts of Reconstruction. In order to avoid any acknowledgement of black empowerment by the Centennial, Lewis's sculpture could not have directly addressed the subject of Emancipation.  Although her white contemporaries were also sculpting Cleopatra and other comparable subject matter (such as Harriet Hosmer's Zenobia), Lewis was more prone to scrutiny on the premise of race and gender due to the fact that she, like Cleopatra, was female:

Paragraph 6: Throughout the Chicano Movement during the 1960s and 1970s Mexican American civil rights movements were at their peak, and one of the most prominent was the Brown Berets. The Brown Berets expressed a combination of civic activism and cultural and ethnic unity, but with elements of militarism to advocate for farm worker's rights, educational reform, anti-war activism and to organize against police brutality. Female members of the Brown Berets served as a valuable asset to the organization and " gave the organization stability by fundraising, answering phone calls, writing letters, pasting up and writing for the newspaper, and running free clinics. They also became instrumental in organizing the marches against the Vietnam War". All three original founders of Las Adelitas de Aztlán, Gloria Arellanes and Gracie and Hilda Reyes had formerly been a part of the Brown Berets, but had felt that the male-dominated leadership was ignoring the demands and concerns of their female members. Though it was clear that women played a critical role in the organization some felt that the secretarial and clerical positions had devalued them as members. With the rise of second-wave feminism in the 1960s women across the racial spectrum beginning expressing a type of gender consciousness that rejected notions of passiveness or submission to male domination in civil rights circles. Many would even break away entirely to start their own organizations. In February 1970 Arellanes, then the minister of correspondence and finance for the East Los Angeles chapter had handed in her letter of resignation to the Brown Berets's Minister of Education Aron Mangancilla stating "There has been a great exclusion on behalf of the male segment and failure of the ministers to communicate with us, among many, many other things". Arellanes had set a precedent that had echoed along with other second wave feminists at the time that despite being a member of an oppressed class of people, the female component of the Mexican American community had often been sidelined via male dominance. Shortly after her resignation Arellanes began organizing a new group at the Euclid Heights Center in East Los Angeles and advertised it as an organization where Chicanas could express themselves and their ideas or a place where the dissatisfied could find a place to be included and welcomed. Gloria Arellanes discusses the reasoning of why she named the group Las Adelitas de Aztlán saying in the book The Chicano Movement Testimonios Of The Movement, "I had come to learn more about the history of the Mexican Revolution of 1910 and was fascinated by the image of La Adelita, the female revolutionary who fought in the revolution… This was part of the Chicana search for historical role models". She continues to speak about the importance of Las Adelitas de Aztlán, saying that the group helped to give birth to Chicana feminism. As a group, Las Adelitas de Aztlán discussed how they were treated as women, and talked about Machismo, specifically the macho mentality of Mexican American males. The group adopted the following slogan: "Porque somos una familia de hermana (Because we are a family of sisters)".

Paragraph 7: Matthew West told CCM Magazines Matt Conner that "'my plan was not necessarily to do multiple projects with that thematic base, but after inviting people to share their story with me, they didn't stop coming in...we received 10,000 stories after my initial request giving people a chance to tell me what to write about. Then after we put out The Story of Your Life, it's almost as if that release sent out an even broader call to people.'" Further, West said that he "'...had people coming up to me on that tour asking if I was going to do another release like that,...I'm not the smartest guy in the room, but I can take a hint. The hint is that there are now over 20,000 stories that have been submitted. It was clear that it was a concept that needed to be done again.'" West replied the last-time they did this that "'we went through six printers; it was on overload. We were not going green at that point,...There were stacks and stacks of paper. As they began to pile up, we realized we needed a better system. We actually created an online database that helps me categorize the stories that I am reading.'" Lastly, West replied that "'I'm reading stories every day and I am still reading stories, even though the record is done. I made a promise to read every single story,...Some days I read 10, other days I ready a 100. Some nights on the bus I stay up most of the night until I have to stop. But it feels important. It feels like what God is calling me to do.'" West evoked how "'the personal creative journey that I am on right now is driven by stories of people's lives that have been shared with me,...When it comes to that, it's a deep, deep well of inspiration. It's really stemmed from this new dialogue that I get to have with fans where they get to tell me their story and what I can write about. I had the honor of shining a light on some of those stories to give them a voice.'" West noted how "'my musical ambition has always been to serve the song-to serve the emotion of the song, the message of the song,...The melody marrying the lyrics in perfect combination is what I always strive toward. When that's your main goal, I tend to have records that are pretty eclectic. I'm not tying myself to a specific style. It's never been about that for me. The style has to serve the lyrics.'" So, West finished by saying "'this new record is called Into the Light because, once again, we are bringing more true stories into the light in the form of a song on this record. Honestly, I can't remember doing anything that's felt more fulfilling than this journey that I have been on.'"

Paragraph 8: Towards the end of 1937, hundreds of overseas Chinese working in Japanese-owned industries in Malaya went on strike. At the time, the Japanese government owned an iron mine in Bukit Besi near Dungun, Terengganu where about 3,000 workers were employed. The iron ore was shipped to Japan and used as raw material to manufacture weapons. Lim believed that if the workers in the Dungun mine went on strike, the Japanese would suffer a huge loss, so he planned to make the workers go on strike. Around February 1938, Lim travelled to Dungun with Zhuang Huiquan () of the Anxi clan association to carry out their plan. Zhuang went to the mine to persuade the workers to go on strike while Lim contacted the local police and gained their support. By early March, Lim and Zhuang achieved success as many workers left the mine and followed them to Singapore. On 11 March 1938, Lim and the Singaporean Chinese community held a welcoming ceremony for the workers, who later resettled and found employment in Singapore.

Paragraph 9: With the independence of the Church of England the role of the papacy in appointing bishops was abolished, but the confirmation became almost formal in character. By 25 Hen. VIII. c. 20, 5. 4 it is provided that after an episcopal election a royal mandate shall issue to the archbishop of the province requiring him to confirm the said election or, in case of an archbishop-elect, to one archbishop and two bishops, or to four bishops, requiring and commanding them with all speed and celerity to confirm it. This practice still prevails in the case of dioceses which have chapters to elect. The confirmation has usually been performed by the archbishop's vicar-general and, in the southern province, at the church of St Mary-le-Bow, London (as the permanent home of the Arches Court); but since 1901 it has also been performed variously at: Church House, Westminster; at Lambeth Palace; at the Archbishop's Faculty Office (1 The Sanctuary, Westminster); and at St Paul's—in consequence of the disorder in the proceedings at St Mary-le-Bow on the confirmation there of Arthur Winnington-Ingram as Bishop of London. All objectors are cited to appear on pain of contumacy after the old form; but although the knowledge that opposition might be offered has been a safeguard against improper nominations, e.g. in the case of Samuel Clarke the Arian, confirmation has never been refused since the Reformation. In 1628, Dr. Rives, acting for the vicar-general, declined to receive objections made to Richard Montagu's election to the See of Chichester on the ground that they were not made in legal form. An informal protest against the confirmation of James Prince Lee as Bishop of Manchester in 1848 was almost immediately followed by another in due form against that of Renn Hampden, Bishop-elect of Hereford. The vicar-general refused to receive the objections and an application to the Queen's bench for a mandamus was unsuccessful, the judges being divided two against two.

Paragraph 10: Used to build call center equipment using regular PCs, MVIP provides a second communications bus within the computer that can multiplex up to 256 full-duplex voice channels from one voice card to another. Digital voice, fax and video is bussed over a ribbon cable connected at the top of each ISA or PCI card. MVIP products make a PC perform like a small-scale PBX. The protocol accommodated for a variety of expansion boards, including trunk interfaces (usually T1 or ISDN), voice processing boards equipment  speech recognition or fax processing. Each board could optionally provide a switch that could interconnect voice channels on the bus, allowing for a flexible routing of calls within the MVIP bus.

Paragraph 11: Returning to Poland, Sarbiewski taught rhetoric, philosophy, and theology at Vilnius University from 1626 to 1635, was then made preacher to King Władysław, and was for four years companion in his travels. The fame of Sarbiewski is as wide as the world of letters. He was gifted with remarkable general talent, especially in music and the fine arts, but his chief excellence was as a poet versed in all the metres of the ancients. He was especially devoted to Horace, whose Odes he knew by heart. He also made the lyrical poetry of Pindar his own. To his familiarity with these great poets he added an industry which has given the splendid yield of his poetic works. The latest edition of these, printed at Stara Wieś in 1892, embraces four books of lyrics, a book of epodes, his posthumous Silviludia (Woodland Notes), and his book of epigrams. Of all these the lyrics furnish the best example of his qualities of mind and heart. All are pitched in a high key of thought, sentiment, or passion. His themes are for the most part love and devotion for Christ Crucified, for Our Blessed Lady, or friendship for a noble patron, such as Bishop Łubieński, Cardinal Francesco Barberini, nephew to Urban VIII, and that pontiff himself, whom he hailed as his Maecenas in several odes of exquisite finish. His noblest and most sustained efforts, however, are his patriotic odes upon the fatherland, the Knights of Poland, and kindred subjects. His tenderest pieces are those in praise of the rose, the violet, and the grasshopper, in which he rivals the grace and happy touch of Horace himself. He was crowned poeta laureatus by King Władysław IV Vasa. Urban VIII named him one of the revisers of the hymns of the Breviary, and he in particular is credited with having softened their previous ruggedness of metre. Some critics have urged that in his love of Horace he went so far as to become servile in imitating him, while others again have made a very virtue out of this close imitation. As a religious he was noted for his love of solitude, turning from the attractions of court life to solitude, prayer, and useful study and occupation.

Paragraph 12: Former Team Lotus employees Peter Collins and Peter Wright organized a deal to take over the team from the Chapman family and in December the new Team Lotus was launched with Mika Häkkinen and Julian Bailey being signed for the 1991 season to drive updated Lotus 102Bs with Judd engines. At the 1991 San Marino Grand Prix, the team scored its first double points finish since the 1988 Brazilian Grand Prix, with Häkkinen in fifth and Bailey in sixth. Despite this, Bailey was soon replaced by Johnny Herbert for the balance of the season.  For the following year, the team signed a deal to use Ford's HB V8 in their new Lotus 107s, designed by Chris Murphy. The team was now short on money and this affected performance, but the car allowed Häkkinen to score 11 points, including two fourth places at the 1992 French Grand Prix (where he had failed to qualify the previous year) and the 1992 Hungarian Grand Prix, while Herbert scored two points for 6th Places at the 1992 South African Grand Prix and 1992 French Grand Prix. The team finished 5th in the Constructors' Championship. Häkkinen, who finished 8th in the 1992 Drivers' Championship, moved to McLaren as a test driver in 1993. He was replaced by Alessandro Zanardi, who was himself replaced by Pedro Lamy after crashing heavily at the 1993 Belgian Grand Prix, where Herbert scored the last two points for Team Lotus. Over the year, the team scored 12 points despite the tight budget and finished 6th in the 1993 Constructors' Championship. Herbert finished 9th in the Drivers' Championship with three 4th placements: the 1993 Brazilian Grand Prix, where he lost 3rd to Benetton's Michael Schumacher shortly before the end of the race; the 1993 European Grand Prix, where he made only one pit stop for tyres; and the 1993 British Grand Prix, where he was not far behind Riccardo Patrese's 3rd placed Benetton at the end, having benefited from the retirements of Ayrton Senna, Martin Brundle and Damon Hill. Zanardi scored one 6th place at the 1993 Brazilian Grand Prix, the last race with both Lotus cars in the points.

Paragraph 13: The name "Gyllenhaal" originated from Nils Gunnarsson Gyllenhaal's father Gunne Olofsson Haal, who was from Hahlegården, a crown homestead in South Härene Parish in the county of Västergötland in West Sweden. Haal comes from the name of the farm estate "Hahlegården". In the Knighthood Letter, signed by Queen Christina, the family name was written in two different ways — first "Gyllenhahl" and then "Gyllenhaal". On the copperplate with his coat of arms now hanging in the House of Nobility (Riddarhuset) in Stockholm, it is spelled "Gyllenhahl". Such ambiguities are typical of the time; it would be several generations before Swedish spelling was more strictly regulated. The prefix Gyllen ("Golden") was the one most used when ennobling someone since the 16th century.

Paragraph 14: The culture of Imperial Russia was very strongly influenced by that of France, and Russian writers accordingly shared the disdain traditionally held by French writers towards spy novels, which was seen as a lowbrow type of literature. In the Soviet Union, espionage was depicted before 1961 as something committed against the Soviet state by its enemies and not as an activity that the Soviet state itself engaged in. Perhaps the best example of this attitude was the founding of SMERSH in 1943, which was an acronym for the wartime slogan Smert' shpionam! ("Death to Spies!"), which reflected the picture promoted by the Soviet state of spies as a disreputable type of person who deserved to be killed without mercy. Furthermore, the legacy of the Yezhovshchina and other Stalinist repression had given the Chekisty, as secret policemen are always called in Russia, a very negative image. In November 1961, Vladimir Semichastny became chairman of the KGB and set out to improve the image of the Chekisty. 

Paragraph 15: The legal origins theory claims that the two main legal traditions or origins, civil law and common law, crucially shape lawmaking and dispute adjudication and have not been reformed after the initial exogenous transplantation by Europeans. Therefore, they affect economic outcomes to date. According to the evidence reported by the initial proponents of such a theory, countries that received civil law would display today less secure investor rights, stricter regulation, and more inefficient governments and courts than those that inherited common law. These differences would reflect both a stronger historical emphasis of common law on private ordering and the higher adaptability of judge-made law.

Paragraph 16: Hatto soon became known to the German king, Arnulf, who appointed him archbishop of Mainz in 891, and he became such a trustworthy and loyal counsellor that he was popularly called the heart of the king. He presided over the important synod at Tribur in 895 and accompanied the king to Italy in 894 and 895, where he was received with great favor by Pope Formosus. In 899, when Arnulf died, Hatto became regent of the Empire and guardian of the young king, Louis the Child, whose authority he compelled Zwentibold, duke of Lorraine, an illegitimate son of Arnulf, to recognize.

Paragraph 17: There are the ruins of a hunting lodge, or grange, for the Prior of Durham, which is a listed building. The monastic grange was built for the priors of Durham by Prior Hugh of Darlington, while he held office between 1258 and 1272, on what is thought to have been the site of an earlier grange. The grange lay within a deer park, which Prior Hugh was granted permission to enclose in 1259. The buildings of the grange were in use throughout the medieval period; a document of 1464 records that the buildings consisted of a hall, chapel, grange and a dairy. The names Priory Farm and Grange Farm testify to the influence of Durham as do the stone remains of the grange including a wall suggesting a three-storey building, described as "impressive" by Pevsner.

Paragraph 18: Introduced in 1996's A Game of Thrones, Samwell is the elder son of Lord Randyll Tarly of Horn Hill and his wife Lady Melessa Florent. A self-professed coward with a love for books and songs, Samwell was forced by his father to abandon his birthright and join the Night's Watch so that his younger brother could become heir to Horn Hill. While at the Wall, he meets Jon Snow and quickly becomes his closest friend and ally. He subsequently appeared in 1998's A Clash of Kings before becoming a point-of-view character in 2000's A Storm of Swords and 2005's A Feast for Crows.

Paragraph 19: The discovery of oil in the region emboldened the MFDC to organise mass demonstrations for immediate independence in 1990, which were brutally suppressed by the Senegalese military. This pushed the MFDC into a full armed rebellion. The following fighting was vicious, and 30,000 civilians were displaced by 1994. Several ceasefires were agreed during the 1990s, but none lasted, often also due to splits within the MFDC along ethnic lines and between those ready negotiate and those who refused to lay down their weapons. In 1992 the MFDC divided into two main groups, Front Sud and Front Nord. Whereas Front Sud was dominated by Jola and called for full independence, Front Nord included both Jola as well as non-Jola tribesmen and was ready to work with the government based on a failed agreement of 1991. Another ceasefire in 1993 led to the break-off of hardline rebel groups from the MFDC. These continued to attack the military. In 1994, Yahya Jammeh took power in the Gambia through a coup d'état. Jammeh would start to provide the MFDC with substantial support, and was even known to recruit MFDC fighters into the Gambian military, reportedly since they were more inclined to be loyal to Jammeh's regime than the people of the Gambia. 

Paragraph 20: The first issue, published in London on 6 March 1665, was edited and published by the Society's first secretary, Henry Oldenburg, four-and-a-half years after the Royal Society was founded. The full title of the journal, as given by Oldenburg, was Philosophical Transactions, Giving some Account of the present Undertakings, Studies, and Labours of the Ingenious in many considerable parts of the World. The society's council minutes dated 1 March 1664 (in the Old Style calendar; equivalent to 11 March 1665 in the modern New Style calendar) ordered that "the Philosophical Transactions, to be composed by Mr Oldenburg, be printed the first Monday of every month, if he have sufficient matter for it, and that that tract be licensed by the Council of this Society, being first revised by some Members of the same". Oldenburg published the journal at his own personal expense and seems to have entered into an agreement with the society's council allowing him to keep any resulting profits. He was to be disappointed, however, since the journal performed poorly from a financial point of view during his lifetime, just about covering the rent on his house in Piccadilly. Oldenburg put out 136 issues of the Transactions before his death in 1677.

Paragraph 21: In 1887 he was created CMG, and in 1888 . He became a large landowner, when he inherited the Dromquinna estate with 4,500 acres in the barony of Dunkerron South (Kerry, Ireland) from his father-in-law Robert Samuel Palmer. There in the townland of Templenoe outside Kenmare he commissioned the architect James Franklin Fuller around 1890 to build Dromquinna House. Colomb became a member of the Irish privy council in 1903 and in 1906 sat on the Royal Commission dealing with congested districts. He was also a Deputy Lieutenant and a Justice of Peace for the county; and in 1895 served as High Sheriff of Kerry. John Colomb was a member of the Carlton Club (then Pall Mall, today St James's Street, London). Being ill for some time, he died, aged 71, after an operation on 27 May 1909 at his London residence, 75 Belgrave Road.

Paragraph 22:  Each team ownership group must demonstrate the financial capacity to operate the team for five years. As part of the process of demonstrating financial capacity, each ownership group must provide detailed financial history (if applicable) and projections (including a detailed budget) for the team to the Federation in a form satisfactory to the Federation. In addition, each team must have and its governing legal documents must designate one principal owner with a controlling interest who owns at least 35% of the team and has authority to bind the team. Such principal owner must have an individual net worth of at least forty million US dollars (US$40,000,000) exclusive of the value of his/her ownership in the league or team and his/her primary personal residence. The principal owner, together with all other owners, must have a combined individual net worth of at least seventy million US dollars (US$70,000,000) exclusive of the value of ownership interests in the league or team and primary personal residences. Federation shall have the right to require an independent audit to establish that the team meets these net worth requirements; the cost of such audit shall be the responsibility of the team or league. The Federation will take reasonable steps to protect from disclosure and limit access to financial information provided under this section

Paragraph 23: Born in Trieste, Cudicini began his professional career with Udinese in 1955, making his debut during the 1955–56 Serie B season, and obtained promotion to Serie A with the club. In his first season in the Italian top division, he collected 13 appearances throughout the season, and marked his Serie A debut with a clean sheet in a 2–0 home win over Palermo on 2 December 1956. In 1958, he joined Roma. After two seasons as the team's back-up goalkeeper behind Luciano Panetti, he was promoted to the team's starting goalkeeper in 1960, and retained the position for the next six seasons, collecting 166 league appearances, and winning the Inter-Cities Fairs Cup in 1960–61 and a Coppa Italia in 1964. He spent the 1966–67 Serie A season with Brescia, helping the club avoid relegation. In 1967, at the age of 32, he joined Milan, where he remained until his retirement in 1972, making 127 league appearances for the club and 183 appearances in all competitions under manager Nereo Rocco; he achieved notable domestic and international success with the club, winning the Serie A title and the Cup Winners' Cup in his first season, followed by the European Cup and the Intercontinental Cup in 1969, and finally the Coppa Italia in 1972. He is Milan's seventh-most capped keeper of all time, behind only Christian Abbiati (380), Sebastiano Rossi (330), Dida (302), Lorenzo Buffon (300), Enrico Albertosi (233), and Dario Compiani (221).

Paragraph 24: On 16 August 1918, King participated in a major assault against the German airfield at Haubourdin, near Lille, that resulted in thirty-seven enemy aircraft being destroyed on the ground. During the action, described by the official history as a "riot of destruction", King set on fire a hangar housing four or five German planes. He also, according to No. 2 Squadron pilot Charles Copp, flew down Haubourdin's main street, waving as he went, his reason being that "the girls in that village must have had a heck of a time with all that bombing and must have been terribly scared so I thought I'd cheer them up a bit". By this time the Lille sector was largely clear of German fighters. The official history recorded that on 25 August, "King went out alone as far as Don railway station, bombed it, machine-gunned a train, and returned among the low clouds—all without seeing any enemy."  The only contact around this time was on 30 August, when King, Thomas Baker and another pilot shot down two DFWs near Laventie.   On 1 September, King destroyed an observation balloon over Aubers Ridge. Three days later he shot down an LVG after attacking a train near Lille with Cobby. He was recommended for the Distinguished Flying Cross (DFC) on 8 September. The award, promulgated in The London Gazette on 3 December, cited his "gallant and valuable service in bombing and attacking with machine gun fire enemy billets, trains, troops etc", during which "he ensure[d] success by descending to low altitudes, disregarding personal danger". On 16 September, following a lull in aerial combat in the region, King destroyed a Fokker biplane over Lille. Around this time he was promoted to captain and flight commander. He took over "A" Flight from Cobby, who had been posted to England. By the end of September, King's tally was eighteen. He registered his final victory in a Camel on 2 October, when he used bombs to send down his fourth balloon.

Paragraph 25: Richard Hoe married Lucy Gilbert Hoe (1813 - Nov 9, 1841) and had two daughters, Emily Amelia Hoe and Adeline Hoe.  Both of these daughters married brothers Cyrus and DeWitt Lawrence.  After Lucy died at the young age of 28, Richard married Anne Corbin Platt Hoe, with whom he had two additional daughters, Anne Corbin Hoe Platt (1852 - 1887) and Mary Gilbert Hoe Harper (1854 - 1925).  His daughter, Anne, died at the young age of 34 during childbirth, and both twins died as well.  Although he lived much of his life in New York City, he spent years renovating "Brightside" and gradually moved the family there about 1857.  The manor house was situated on 53 acres in the Bronx. Hoe died on June 7, 1886, in Florence, Italy.

Paragraph 26: Route 63 follows a mostly northwest-southeast path its entire route, and is mostly a 2 lane road with some 4 lane sections.  It begins at the corner of Whalley Avenue and Fitch Street in New Haven where Route 10 turns onto Fitch Street.  Heading northwest on Whalley Avenue, it almost immediately passes the eastern end of Route 243 and the northern end of Route 122.  About 0.6 miles later, it leaves Whalley Avenue for Amity Road at the southern end of Route 69.  It then passes under the Wilbur Cross Parkway (Route 15), offering southbound access only.  After crossing into Woodbridge, the road becomes less suburban in nature.  In Woodbridge, it intersects the eastern end of Route 114, and the southern/eastern end of Route 67.  It then crosses into Bethany, where it has a brief (0.1 mile) concurrency with Route 42.  It then enters Naugatuck, where the road takes on a more suburban character.  It then meets the Route 8 expressway at Exit 26 before crossing the Naugatuck River into the downtown area.  It then passes by the western end of Route 68 before becoming more rural again.  After clipping the southwest corner of Waterbury, it enters Middlebury.  After meeting the northern end of Route 188, it intersects I-84 at Exit 17, with access to/from the west.  Access to/from I-84 east is provided by Route 64 at the next intersection.  Route 63 then enters Litchfield County and the town of Watertown.  Here it is a major retail strip in the southern part of town.  It meets the northern end of Route 73 before crossing US 6 in the center of town.  It then becomes a minor arterial road north of town, and passes by the eastern end of Route 132 before entering Morris.  In Morris, it has junctions with Route 109 and the northern end of Route 61.  It then enters Litchfield, where it meets US 202 at the Litchfield Green.  Leaving Litchfield, Route 63 becomes a minor rural road as it passes into Goshen.  It meets Route 4 at a traffic circle in the center of town.  North of there, it passes into Cornwall, where it meets the north end of Route 43, then into the town of Canaan.  It has one junction with the southern end of Route 126, which leads to Falls Village.  Route 63 ends approximately 1.5 miles later at US 7. 

Paragraph 27: The Battle of Shepherdstown, also known as the Battle of Boteler's Ford, took place September 19–20, 1862, at Boteler's Ford along the Potomac River, during the Maryland campaign of the American Civil War.  After the Battle of Antietam on September 17, General Robert E. Lee and the Confederate Army of Northern Virginia withdrew across the Potomac.  Lee left a rear guard commanded by Brigadier General William N. Pendleton at Boteler's Ford.  On September 19, elements of the Union V Corps dueled with Pendleton's artillery before pushing a short distance across the river at dusk.  Pendleton inaccurately informed Lee that all of the artillery of the rear guard had been captured.  On the morning of September 20, the Confederates counterattacked with A. P. Hill's Light Division, forcing the Union units back across the Potomac.  One Union unit, the 118th Pennsylvania Infantry Regiment, did not withdraw at the same time as the others and suffered heavy losses.  Lee's army continued its retreat into the Shenandoah Valley after the battle.

Paragraph 28: A fixture, as a legal concept, means any physical property that is permanently attached (fixed) to real property (usually land). Property not affixed to real property is considered chattel property. Fixtures are treated as a part of real property, particularly in the case of a security interest. A classic example of a fixture is a building, which, in the absence of language to the contrary in a contract of sale, is considered part of the land itself and not a separate piece of property. Generally speaking, the test for deciding whether an article is a fixture or a chattel turns on the purpose of attachment. If the purpose was to enhance the land, the article is likely a fixture; if the article was affixed to enhance the use of the chattel itself, the article is likely a chattel.

Paragraph 29: Leite Lopes began his university studies in 1935, enrolling in industrial chemistry at the Chemistry School of Pernambuco. In 1937, while presenting a paper to a scientific conference in Rio de Janeiro, the young student met Brazilian physicist Mário Schenberg and was introduced by him in São Paulo to Italian physicists Luigi Fantappiè and Gleb Wataghin. All three were working on research in physics at the then recently created University of São Paulo, amid a climate of great intellectual excitement and a breeding ground for a bright young generation of what would become the élite of Brazilian physics, such as César Lattes, Oscar Sala, Roberto Salmeron, Jayme Tiomno and Marcelo Damy de Souza Santos. Encouraged to study physics by what he saw, Leite Lopes moved to Rio de Janeiro after hist graduation in 1939. He took the entrance examinations to the National Faculty of Philosophy of the University of Brazil in 1940 and graduated a bachelor in physics in 1942. Accepting an invitation by Carlos Chagas Filho, Leite Lopes started to work in the same year the Institute of Biophysics of the Federal University of Rio de Janeiro, but soon moved to the University of São Paulo to take up graduate studies in quantum mechanics with his teacher, friend and sponsor, Mário Schenberg. His main work during this time was on the calculation of Dirac's radiation field of electrons.

Paragraph 30: Virginia Woolf has begun writing the book Mrs Dalloway in her home in the town of Richmond outside London. Virginia has experienced several nervous breakdowns and suffers from depression. She is constantly under the eye of her servants and her husband, Leonard, who has begun a publishing business at home, Hogarth Press, to stay close to her. Virginia's sister, Vanessa, and her children, Julian, Quentin, and Angelica, come over for an afternoon visit. She and Vanessa talk about Vanessa's life in London and Virginia's mental condition. She longs for a life similar to Vanessa’s, living in London. Vanessa's children find a dead bird. Virginia and Angelica make a funeral for the bird. Virginia lies down beside the bird and looks into its eyes. She sees herself in the dead bird, suffering and dying in her circumstances. Everyone goes back inside and Virginia continues writing her book. She says that she was going to kill her heroine but instead chooses to kill another character in the book. Before Vanessa leaves, Virginia passionately kisses her sister. It is clear Virginia wants them to stay and wants her sister's life. After their departure, Virginia flees to the train station, where she is awaiting a train to London. Leonard arrives to stop her, and they argue. He tells her that Richmond was intended to soothe her mental illness and that he lives in constant fear that she will take her own life. She replies that she also lives with that fear but argues that she has the right to choose her own destiny and that she would prefer London, even if it means her death, to remaining stifled in Richmond. Leonard mournfully concedes, and they return home, where Virginia begins writing again. Leonard questions her as to why someone has to die. Virginia says “In order that the rest of us should value life more.” Leonard asks who will die and Virginia says "The poet will die, the visionary.”

Question: The text discusses how acute generalized exanthematous pustulosis (AGEP) differs from other severe cutaneous adverse reactions (SCARs) disorders in terms of the level of evidence supporting the underlying mechanism by which a drug or its metabolite stimulates certain types of T cells. Studies indicate that the mechanism involves subverting the antigen presentation pathways of the innate immune system. The drug or metabolite binds to a host protein to form a non-self epitope, which is then presented to T cells by antigen-presenting cells. This can lead to an attack on the body's own tissues. However, the ability of a drug to induce AGEP is limited to individuals who express specific human leukocyte antigen (HLA) serotypes targeted by the drug. The text also mentions that HLA serotypes associated with AGEP have not been identified, unlike for other SCARs disorders. Additionally, a specific T cell receptor variant has been linked to other SCARs disorders but not AGEP.
Answer: Paragraph 3