Interleukin-1 family
Nomenclature

Interleukin-1 family

Section Title: Nomenclature
Table Section Text: None

Name	Family name	Receptor	Coreceptor	Property	Chromosomal location

IL-1α	IL-1F1	IL-1RI	IL-1RAcP	Proinflammatory	2q14

IL-1β	IL-1F2	IL-1RI	IL-1RAcP	Proinflammatory	2q14

IL-1Ra	IL-1F3	IL-1RI	NA	Antagonist for IL-1α, IL-1β	2q14.2

IL-18	IL-1F4	IL-18Rα	IL-18Rβ	Proinflammatory	11q22.2-q22.3

IL-36Ra	IL-1F5	IL-1Rrp2	NA	Antagonist for IL-36α, IL-36β, IL-36γ	2q14

IL-36α	IL-1F6	IL-1Rrp2	IL-1RAcP	Proinflammatory	2q12 - q14.1

IL-37	IL-1F7	Unknown	Unknown	Anti-inflammatory	2q12 – q14.1

IL-36β	IL-1F8	IL-1Rrp2	IL-1RAcP	Proinflammatory	2q14

IL-36γ	IL1-F9	IL-1Rrp2	IL-1RAcP	Proinflammatory	2q12 – q21

IL-38	IL-1F10	IL-1Rrp2	Unknown	Anti-inflammatory	2q13

IL-33	IL-1F11	ST2	IL-1RAcP	Th2 responses, proinflammatory	9p24.1

Sentence(s)

IL-1RI and IL-1RAcP serve as receptors and coreceptors for IL-1α and IL-1β.

final_sentence: IL-1RI and IL-1RAcP serve as receptors and coreceptors for IL-1α and IL-1β.