Amesergide
Pharmacodynamics

Amesergide

Section Title: Pharmacodynamics
Table Section Text: None

Site	Ki (nM)	Species	Ref

5-HT1A	177.3	Rat

5-HT1B	ND	ND	ND

5-HT1D	57.9	Cow

5-HT2A	15.1 12.4	Human Rat

5-HT2B	1.96	Human

5-HT2C	6.27 13.27	Human Pig

5-HT3	>10,000	Rat

5-HT6	ND	ND	ND

5-HT7	78.0	Human

α1	730	Rat

α2	50 13 (MB)	Rat

β	>10,000	Rat

D1	150	Rat

D2	520	Rat

H1	>10,000	Rat

mACh	>10,000	Rat

Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site.

Sentence(s)

Amesergide's 5-HT1D has Kᵢ = 57.9 nM.

final_sentence: Amesergide's 5-HT1D has Kᵢ = 57.9 nM.