List of AM cannabinoids

List of AM cannabinoids

Section Title:
Table Section Text: None

Name	Class	Ki at CB1	Ki at CB2	Selectivity	CLogP	Structure

AM-087	Dibenzopyran	0.43nM	6.47	-

AM-251	Pyrazole derivative	7.5nM	7.08	-

AM-279

AM-281

AM-356	17.9nM	868nM	5.55	-

AM-374

AM-381

AM-404	7.02	-

AM-411	6.80nM	52.0nM	-

AM-630	32.1nM	CB2 (165x)	4.19	-

AM-661

AM-678	9.00nM ± 5.00	2.94nM ± 2.65	5.68	-

AM-679	13.5nM	49.5nM	6.04	-

AM-694	0.08nM	1.44nM	CB1 (18x)	5.54	-

AM-735	8.9nM	7.4nM

AM-855	22.3nM	58.6nM	7.1	-

AM-881	5.3nM	95nM

AM-883	9.9nM	226nM

AM-905	1.2nM	5.3nM	4.98	-

AM-906	0.8nM	9.5nM	4.98	-

AM-919	2.2nM	3.4nM	6.21	-

AM-926	2.2nM	4.3nM

AM-938	1.2nM	0.3nM	5.92	-

AM-1116	7.4nM

AM-1172

AM-1220	3.88nM	73.4nM	4.73	-

AM-1221	52.3nM	0.28nM	CB2 (187x)	-

AM-1235	1.5nM	20.4nM	CB1 (13x)	-

AM-1241	3.4nM	CB2 (80x)	-

AM-1248	-

AM-1710	Cannabilactone	CB2 (54x)

AM-1714	Cannabilactone	CB2 (490x)	6.17	-

AM-1902

AM-2201	1.0nM	2.6nM	5.18	-

AM-2212	1.4nM	18.9nM

AM-2213	3.0nM	30nM	CB1 (10x)

AM-2232	0.28nM	1.48nM	4.75	-

AM-2233	1.8nM	2.2nM	5.09	-

AM-2389	0.16nM	CB1 (26x)	6	-

AM-3102	33µM	26µM

AM-4030	0.7nM	8.6nM	CB1 (12x)	6.17	-

AM-4054	2.2nM	CB1 (40x)

AM-4056	0.041nM	6.51	-

AM-4113

AM-6545	4.06	-

Sentence(s)

AM-4054 has CB₁ affinity of 2.2nM and a 40x selectivity for CB₁.

final_sentence: AM-4054 has CB₁ affinity of 2.2nM and a 40x selectivity for CB₁.