Blonanserin
Pharmacodynamics

Blonanserin

Section Title: Pharmacodynamics
Table Section Text: None

Receptor	Ki [nM] (Blonanserin)*	Ki [nM] (N-deethylblonanserin)*

D1	1070	1020

D2	0.142	1.38

D3	0.494	0.23

D4	150

D5	2600

5-HT1A	804

5-HT2A	0.812	1.28

5-HT2C	26.4	4.50

5-HT6	11.7	5.03

5-HT7	183

α1	26.7 (Rat brain)	206 (Rat receptor)

α2	530 (Rat cloned)

M1	100

H1	765

Sentence(s)

Blonanserin acts as a 5-HT2A (Kᵢ = 0.812 nM) and D₂ receptor (Kᵢ = 0.142 nM) and α₁ receptors (Kᵢ = 26.7 nM).

final_sentence: Blonanserin acts as a 5-HT2A (Kᵢ = 0.812 nM) and D₂ receptor (Kᵢ = 0.142 nM) and α₁ receptors (Kᵢ = 26.7 nM).