Selective internal radiation therapy
Radionuclides and microspheres

Selective internal radiation therapy

Section Title: Radionuclides and microspheres
Table Section Text: None

Parameter	Resin	Glass	PLLA

Trade name	SIR-Spheres	TheraSphere	QuiremSpheres

Manufacturer and location	Sirtex Medical, Lane Cove, Australia	BTG, Ottawa, Canada	Quirem Medical, Deventer, The Netherlands

Mean diameter	32 µm	25 µm	30 µm

Specific gravity (compared to blood)	1.6 g/dL (150%)	3.6 g/dL (300%)	1.4 g/dL (130%)

Activity per particle	50 Bq	1250-2500 Bq	330-450 Bq

Number of microspheres per 3 GBq vial	40-80 million	1.2 million	8 million

Material	resin with bound yttrium	glass with yttrium in matrix	PLLA with holmium

Radionuclide (half life)	Yttrium-90 (64.1 hours)	Yttrium-90 (64.1 hours)	Holmium-166 (26.8 hours)

Beta-radiation (Emax)	2.28 MeV	2.28 MeV	1.77 MeV (48.7%) 1.85 MeV (50.0%)

Gamma-radiation	81 KeV (6.7%)

Sentence(s)

The microsphere of selective internal radiation therapy is based on the radionuclide holmium-166 and is made of PLLA.

final_sentence: The microsphere of selective internal radiation therapy is based on the radionuclide holmium-166 and is made of PLLA.