Embryonal fyn-associated substrate
Structure

Embryonal fyn-associated substrate

Section Title: Structure
Table Section Text: None

Domain	Position	Length	Function

N-terminal	1 - 4	4 aa	This region has no assigned function

SH3-domain	5-68	64 aa	Binds to proline-rich motif containing proteins, such as FAK, PTK2B, C3G, PTP-PEST, PTP1B, CIZ and FRNK.

SH2-binding region	69 - 350	282 aa	Contains YxxP motifs capable of being phosphorylated on tyrosine residues, then binding SH2 domains.

Serine rich domain	351 - 488	138 aa	Conserved domain structure encompassing 4 α-helices bundle has a docking function.

C-terminal	489 - 561	73 aa	Conserved domain structure encompassing 4 α-helices bundle has a docking function; homo- or heterodimerization; focal adhesion targeting.

Sentence(s)

A serine-rich domain encompassing a 4 α-helix bundle (amino acids 351-488 for human EFS).

final_sentence: A serine-rich domain encompassing a 4 α-helix bundle (amino acids 351-488 for human EFS).