Estradiol acetate
Available forms

Estradiol acetate

Section Title: Available forms
Table Section Text: None

Route	Ingredient	Form	Dose	Major brand names

Oral	Estradiol	Tablets	0.1, 0.2, 0.5, 1, 2, or 4 mg per tablet	Estrace, Ovocyclin

Estradiol acetateb	Tablets	0.45, 0.9, or 1.8 mg per tablet	Femtrace

Estradiol valerate	Tablets	0.5, 1, 2, or 4 mg per tablet	Progynova

Intranasal	Estradiolb	Nasal sprays	150 µg per spray (60 sprays per bottle)	Aerodiol

Transdermal	Estradiol	Patches	14, 25, 37.5, 50, 60, 75, or 100 µg E2 per 24 hours for 3–4 or 7 days	Climara, Estraderm, Vivelle

Gel dispensers	0.06% (0.87 or 1.25 g gel or 0.52 or 0.75 mg E2 per activation)	Elestrin, EstroGel

Gel packets	0.1% (0.25, 0.5, or 1.0 g gel or 2.5, 5, or 10 mg E2 per packet)	DiviGel, Sandrena

Emulsions	0.14% (1.74 g emulsion or 4.35 mg E2 per pouch; delivers 50 µg E2 per day)	Estrasorb

Sprays	1.53 mg per spray	Evamist

Vaginal	Estradiol	Tablets	10 or 25 µg per tablet	Vagifem

Creams	0.01% (0.1 mg E2 per 1.0 g cream)	Estrace

Suppositoriesb	4 or 40 μg per suppository	Ovocyclin

Inserts	4 or 10 µg per insert (replaced daily for 2 weeks and then twice weekly)	Imvexxy

Rings	2 mg per ring (provides 7.5 µg E2 per 24 hours for 3 months)	Estring

Estradiol acetate	Rings	12.4 or 24.8 mg per ring (provide 50 or 100 µg E2 per 24 hours for 3 months)	Femring

Intramuscular injection	Estradiola	Ampoules	1.0 mg/mL	Juvenum E

Estradiol benzoate	Vials/ampoules	0.167, 0.2, 0.333, 1, 1.67, 2, 5, 10, 20, or 25 mg/mL	Progynon-B

Estradiol cypionate	Vials/ampoules	1, 3, or 5 mg/mL	Depo-Estradiol

Estradiol dipropionateb	Vials/ampoules	0.1, 0.2, 0.5, 1, 2.5, or 5 mg/mL	Di-Ovocylin, Progynon-DP

Estradiol enantate	Vials/ampoules	5 or 10 mg/mL (available only in combination with a progestin)	Perlutal, Topasel

Estradiol undecylateb	Vials/ampoules	100 mg/mL	Delestrec, Progynon Depot 100

Estradiol valerate	Vials/ampoules	5, 10, 20, or 40 mg/mL	Delestrogen, Progynon Depot

Polyestradiol phosphate	Vials/ampoules	40 or 80 mg per vial/ampoule	Estradurin

Subcutaneous	Estradiolc	Implants	20, 25, 50, or 100 mg per implant (usually replaced every 6 months)	Estradiol Implants, Meno-Implant

Abbreviations: E2 = Estradiol. Footnotes: a = Encapsulated in microspheres.

Sentence(s)

Estradiol acetate comes in the form of 12.4 or 24.8 mg vaginal rings that release 50 or 100 μg/day estradiol for 3 months (Femring).

final_sentence: Estradiol acetate comes in the form of 12.4 or 24.8 mg vaginal rings that release 50 or 100 μg/day estradiol for 3 months (Femring).