ALDH1A2

醛脫氫酶1家族成員A2（Aldehyde dehydrogenase 1 family, member A2），簡稱為ALDH1A2，或稱為視黃醛脫氫酶2（簡寫為RALDH2），是在人體內一種由ALDH1A2基因編碼的酶。此蛋白為醛脫氫酶蛋白家族成員，是負責催化視黃酸到視黃醛的合成的酶。視黃酸是維生素A（即視黃醇）的活性衍生物，是一種旁分泌激素信號分子，主要作用於發育中的組織和成年組織中。對小鼠中類似基因的研究表明，這種酶和細胞色素CYP26A1同時確立局部胚胎組織中的視黃酸濃度，促進後部器官發育和防止脊柱裂。ALDH1A2基因已確認有三種可編碼不同亞型蛋白的轉錄變異體。

**參考文獻**

**拓展閱讀**
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