Edit Requests 

'The relationship of acid-base homeostasis and diet and disease "has been a subject of considerable speculation for at least several centuries".[2]'
 This statement is a partial paraphrase and not completely accurate from the source statement. Why not use the whole source quote for accuracy?
"The study of acid–base equilibrium and its relationship to the diet and disease has been a subject of considerable speculation for at least several centuries"
Note "the study" has been eliminated from the statement and injects a different meaning. The source author should be quoted in the text when a quote is used. Isn't there a WP rule on this? ~~~~