Cut-off 

The article mentions that several plot points of recent comics (Decimation, "Avengers Disassembled", Thor's destruction of Asgard) didn't occur in MC2 continuity, and on Spider-Girl's page it says that "Spider-Man: The Other" never occurred either. Given that would it be accurate to say categorically that there's some cut-off point after which events in Earth-616 are no longer canonical? If so, when and where do you think it would be located? I suppose such a statement might be too broad, and some events may not have been explicitly referenced as happening or not happening but...well, I don't know MC2.