2012 (UTC) 

 I arrived at this page this morning while reviewing nuclear receptors.  Although I think this is an interesting use of Wikipedia, I share Mylittlezach's concerns that this seems to fall outside of the mainstream understanding of how metabolism works.  I wonder if the course that you took leapt to conclusions about some basic science that simply isn't understood yet.  For example, I think we're very far from understanding how PPARs work.  While I feel challenged to investigate some of these statements, I would strongly urge the primary author to examine the literature independent of his course; perhaps verify with some of the more widely read textbooks.   11:38, 28 June