, 18 September 2011 (UTC) 
 :::I can understand your confusion, as this particular article falls under two guidelines, WP:MEDRS, and WP:FRINGE (fringe for Wikipedia being any "ideas that depart significantly from the prevailing or mainstream view in its particular field" - in this case, low dose naltrexone has not been accepted as a treatment for any disease by the mainstream medical community). When dealing with WP:FRINGE medical topics, it is often necessary to use less than ideal sources for information, as there is not a lot of secondary source scholarship in the mainstream sources due it being fringe.  In this case, the website meets this lower threshold; on the opposite end, extraordinary claims require extraordinary sources, so any discussion of how wonderful a miracle drug LDN is would require a high bar to meet, and Medical Hypotheses does not (I would not consider it a reliable source for much of any information, health related or not - it is that bad). The use of secondary sources is to determine how much due weight to give to any particular subject; that is why we avoid primary sources, because we use the secondary sources to determine how much weight in coverage to give.  I hope this helps.   18:39