How to prevent the extinction of the human species?


Answer: Humans are vulnerable to many different cataclysmic events. 
One way is to migrate and reside in other planets, solar systems and even galaxies. Earth is a single point of failure. 
Another consideration is to merge with AI and exist in virtual reality as a non-biological species. 
Preserving human genetic material in doomsday vaults, so that humans can be revived/resurrected in the future.