BSC-LT/ACAData huggingface dataset:
[en] In this work, involvement of oxidative stress in rheumatoid arthritis (RA) and age-related vascular dysfunction has been studied. In RA, characterized by synovial inflammation, mitochondrial alterations that might participate in the course of the disease have been found. In this work, the link between mitochondrial dysfunction in human synoviocytes and the inflammation level has been investigated. Inhibition of mitochondrial function has been found to induce the inflammatory response in synoviocytes in terms of oxidative stress induction and production of the inflammatory mediators COX-2, PGE2 and IL-8. Besides, it aggravates the inflammatory response induced by IL-1β and promotes angiogenesis. The natural polyphenol resveratrol was able to prevent the effects of mitochondrial dysfunction. On the other hand, during aging it has been described a diminished activity of the antioxidant response factor Nrf2 and an impaired angiogenic response that affects microcirculation in several tissues. In this work, we determined whether impaired Nrf2 activity affects angiogenic capacity of coronary artery endothelial cells. It was found that Nrf2 dysfunction impairs angiogenic processes of migration, proliferation, adhesion, and tube formation. Besides, it sensitizes endothelial cells to apoptotic death.

[gl] Neste traballo estudiouse a implicación do estrés oxidativo na artrite reumatoide (AR) e na disfunción vascular asociada ao envellecemento. Na AR, caracterizada pola inflamación no tecido sinovial, encontráronse alteracións mitocondriais que poden participar no curso da enfermidade. Neste traballo investigouse a relación entre a disfunción mitocondrial dos sinoviocitos humanos co grao de inflamación. Observouse que a inhibición da función mitocondrial induce a resposta inflamatoria nos sinoviocitos en canto a inducción de estrés oxidativo e producción dos mediadores inflamatorios COX-2, PGE2 e IL-8. Ademáis, agrava a resposta inflamatoria inducida por IL-1β e promove a anxioxénese. O polifenol natural resveratrol foi capaz de previr os efectos da disfunción mitocondrial. Por outra parte, durante o envellecemento tense descrito unha disminución na actividade do factor de resposta antioxidante Nrf2 e unha resposta anxioxénica deteriorada que afecta á microcirculación en certos tecidos. Neste traballo determinouse se a disfunción da actividade Nrf2 afecta á capacidade anxioxénica de células endoteliales de arteria coronaria. Encontrouse que o silenciamento de Nrf2 nestas células inhibe os procesos anxioxénicos de migración, proliferación, adhesión e formación de tubos, e que ademáis sensibiliza ás células endoteliales á morte por apoptose.
[en] The objective of this project is the design and implementation of a monitoring soil prototype using IoT technology, providing the user important information for making improvement decisions. For this, measurable parameters have been defined associated to quality and productivity soil control. One of the main difficulties is the deployment of sensors in wide and remote soil areas. To address this problem, a set of sensors with support for LoRa technology is chosen. Furthermore, we use devices based on Raspberry Pi with WiFi connectivity for the implementation of sensor nodes located in places with access to a more common communication network. The last is the case of the device that monitors the fill level of the fertilizer tanks. The system is also supported by a cloud computing and IoT platform, specifically Amazon Web Services (AWS). This platform is used for the integration of data from the sensors, for the persistent storage and analysis of sensor data and for the notification of events and alerts via email in case of detecting values outside the configured ranges. Finally, all the components are integrated and tested across different scenarios to validate the whole system.

[gl] O obxectivo do presente proxecto consiste en deseñar e implementar un sistema prototipo de monitorización de terreos de cultivo utilizando tecnoloxías IoT, achegando ao usuario información clave para tomar decisións de mellora. Para iso definíronse uns parámetros medibles relacionados co control da calidade e produtividade dos terreos. Unha das principais dificultades é o despregamento de sensores en áreas de cultivo amplas e afastadas. Para abordar este problema selecciónanse sensores con soporte para a tecnoloxía de comunicación LoRa. Doutra banda, utilízanse dispositivos baseados en Raspberry Pi con conectividade WiFi para a implementación dos nodos situados en instalacións con cobertura mediante redes convencionais. Isto último sería a implementación dun dispositivo para o control do nivel almacenado de fertilizante. O sistema complétase cunha plataforma de computación na nube, Amazon Web Services (AWS). Na devandita plataforma resólvese a integración de datos provenientes dos sensores, o seu almacenamento persistente e a análise dos mesmos para envío de alertas vía correo electrónico en caso de detectarse valores fóra dos rangos configurados. Finalmente, intégranse e proban todos os compoñentes sobre distintos escenarios para validar o funcionamento do sistema
[en] From 2006 to the end of 2008, the SEREA project, Fishing and Shellfishing Supplementary Activities, brought together fishing organizations, public administrations, universities and innovation and dissemination centers from three fishing regions in Europe: Galicia, Brittany and Sardinia. The main goal was to promote the creation of a social, economic and labor restructuration model in the coastal fishing sector, based on the philosophy of promoting social participation in the management of change.

[gl] Dende 2006 a fins de 2008 desenvolveuse o proxecto SEREA Actividades complementarias da pesca e do marisqueo, que reuniu a Organizacións pesqueiras, Administracións, Universidades e Centros de Innovación e Divulgación de tres rexións pesqueiras de europa: Galicia, Bretaña e Cerdeña. O obxectivo principal foi impulsar a creación dun modelo de reestruturación socioeconómica e laboral no sector pesqueiro de baixura, dende unha filosofía de promoción da participación social na xestión do cambio.
[en] Green Public Procurement is a main tool in the attaining savings in the Public Administration running costs, reducing the environmental impact of the sector activities and encouraging innovation and development of "green" technologies, products and services, looking for a model of sustainable growth in the long run. This study examines the current legal map in terms of the possibilities of including environmental criteria in public procurement procedures, pouring light on two major dark spots on its implementation: the legal uncertainty and not knowing of its advantages.

[gl] A Contratación Pública Verde é unha ferramenta central na consecución dos obxectivos de aforro en gastos correntes da Administración Pública, de redución do impacto ambiental das actividades do sector e de estímulo á innovación e desenvolvemento de tecnoloxías, produtos e servizos "verdes", na procura dun modelo de crecemento sostible a longo prazo. Este estudo analiza o mapa xurídico actual en canto ás posibilidades na inclusión de criterios medioambientais nos procedementos de Contratación Pública, deitando luz sobre dous dos principais puntos escuros na súa implantación: a inseguridade xurídica e o descoñecemento das súas vantaxes.
[en] Sustainability and competitiveness are key concepts in an ever-changing society. In Os Ancares, in the livestock sector, they are particularly important when analysing and comparing business models that will have a direct impact on the viability of this activity in the long term. Finding the balance between maintaining and improving current living conditions without compromising the opportunities of future generations and seeking economic efficiency by serving and retaining the market play a crucial role in the viability of the livestock farmers' business in the region. When we talk about traditional business models in livestock farming, we are referring to practices and commercial structures that, historically, were predominant in livestock farming, even if they have been passed down through the generations. On the other hand, when we mention cooperative models, we would focus on the voluntary association of producers who seek to optimize aspects such as production and marketing, with the aim of achieving common benefits. Commercial distribution, as a bridge between production in general and the final consumer, becomes the focus of this analysis, because through the comparison between traditional and cooperative models we seek to understand how the choice of one model or the other can impact not only on the economic viability of the livestock sector, but also on the environmental sustainability and social cohesion of those who live there.

[gl] Sostibilidade e competitividade preséntanse como conceptos claves nunha sociedade que cambia continuamente. En Os Ancares, no sector da gandaría, cobran especial importancia á hora de analizar e comparar os modelos comerciais que repercutirán directamente na viabilidade desta actividade no largo prazo. Encontrar o equilibrio entre manter e mellorar as condicións de vida actuais sen comprometer as oportunidades das xeracións futuras e buscar a eficiencia económica atraendo e retendo mercado xogan un papel crucial na viabilidade do negocio dos gandeiros da rexión. Cando falamos de modelos de negocio tradicionais na gandaría estaríamos facendo referencia a prácticas e estruturas comercias que, historicamente, foron predominantes na actividade gandeira, incluso sendo estas transmitidas xeracionalmente. Por outra parte, cando facemos mención aos modelos cooperativistas, o foco situariámolo na asociación voluntaria de produtores e produtoras que buscan optimizar aspectos como a produción ou comercialización, co obxectivo de lograr beneficios comúns. A distribución comercial, coma ponte entre a produción gandeira e o consumidor final, convértese no centro de este análise, pois a través da comparación entre os modelos tradicionais e cooperativistas búscase comprender como a elección dun modelo ou outro pode impactar non só na viabilidade económica do sector gandeiro, senón tamén na sostibilidade ambiental e na cohesión social daqueles que residen/traballan na zona.
[en] Introduction: The increase in life expectancy makes the aging of populations worldwide and state increasingly. Therefore, it is vitally important that the different institutions provide quality gerontological services, following a model of Person Centered Care, and working through significant occupation, whose specialists are the occupational therapists. Objective: To explore the experiences of a group of elderly people of a day center in A Coruña, using significant occupations as a treatment tool in Occupational Therapy, and thus be able to analyze if there is a relationship with the areas of social participation and leisure. Methodology: A qualitative methodology of phenomenological type has been carried out. The techniques and data collection tools have been 9 semi-structured interviews, a discussion group, a field diary and participant observation. A total of 9 participants have been selected. Results: Four categories have emerged: 1) "Self-perception of occupational performance"; 2) "The value of significance"; 3) "Importance of leisure in the daily life of users"; 4) "Importance of social participation in their day to day". Discussion: The results of the research are compared and compared with the reviewed scientific literature on aging, significance and occupational areas of leisure and social participation. Conclusions: There is a very close relationship between the use of significant activities as a treatment tool and the areas of social participation and leisure.

[gl] Introducción: O aumento da esperanza de vida fai que o envellecemento das poboacións a nivel mundial e estatal sexa cada vez maior. Por isto, é de vital importancia que as diferentes institucións proporcionen servicios xerontolóxicos de calidade, que sigan un modelo de Atención Centrado na Persoa, e traballen a través da ocupación significativa, da que os profesionales especialistas son os e as terapeutas ocupacionais. Obxectivo: Explorar as vivencias dun grupo de persoas maiores dun centro diurno de A Coruña, empregando as ocupacións significativas como ferramenta de tratamento en Terapia Ocupacional, e así poder analizar se gardan relación coa áreas de participación social e ocio. Metodoloxía: Levouse a cabo unha metodoloxía cualitativa de tipo fenomenolóxico. As técnicas e ferramentas de recollida de datos foron: 9 entrevistas semiestructuradas, un grupo de discusión, un diario de campo e a observación participante. Foron seleccionados un total de 9 participantes. Resultados: Emerxeron catro categorías 1) "Autopercepción do desempeño ocupacional; 2) "O valor da significatividade"; 3) "Importancia do ocio na vida diaria dos usuarios/as"; 4) "Importancia da participación social no seu día a día". Discusión: Contrástanse e compáranse os resultados da investigación coa literatura científica revisada en materia de envellecemento, significatividade e áreas ocupacionais de ocio e participación social. Conclusións: Existe unha relación moi cercana entre a utilización de actividades significativas como ferramenta de tratamento e as áreas de ocio e partipación social.
[en] A new model of discrete choice between alternatives of a geographical nature is proposed in this thesis, the spatially correlated nested logit (SCNL) model. This type of choices are generally characterized by the existence of a high number of alternatives and the presence of correlation, at least spatial, between them. The current literature on discrete choice models considers two approaches for this type of choice, which are analyzed in this thesis. The proposed model combines both approaches without adding unknown parameters, it presents a closed mathematical structure and it is compatible with mixed specifications that allow variations in the tastes of those who decide. The SCNL model is formulated and analyzed in this thesis, where it is also applied to a real case, to model the choice of residential location in an urban context, which is a key problem in transport planning and urban economics. The empirical results with the new model significantly improve those obtained with the current models. In addition, a spatial metric for spatial zoning with different sizes and irregular shapes is proposed, very common in administrative areas of European cities. The models specified with the proposed spatial metric obtained empirical results that were significantly better than those obtained with the rest of the spatial metrics considered.

[gl] Nesta tese proponse un novo modelo de elección discreta entre alternativas de natureza xeográfica, o modelo spatially correlated nested logit (SCNL). Neste tipo de elección espérase un elevado número de alternativas e a presenza de correlación, polo menos espacial, entre elas. A literatura actual sobre modelos de elección discreta considera dous enfoques para este tipo de eleccións, que se analizan nesta tese. O modelo proposto combina ambos enfoques sen engadir parámetros descoñecidos, presenta unha estrutura matemática pechada e é compatible con especificacións mixtas que permiten variacións nos gustos de quen decide. O modelo SCNL formúlase e analízase nesta tese, onde tamén se aplica a un caso real, para modelizar a elección da localización residencial nun contexto urbano, que é un problema clave na planificación do transporte e na economía urbana. Os resultados empíricos co novo modelo melloran significativamente os obtidos cos modelos actuais. Ademais, proponse unha métrica espacial para zonificacións do espazo con diferentes tamaños e formas irregulares, moi común en áreas administrativas das cidades europeas. Os modelos especificados coa métrica espacial proposta obtiveron resultados empíricos significativamente mellores que co resto de métricas espaciais consideradas.
[en] Parametric design is a new approach to design in which the designer focuses on creating an algorithm that allows him to explore several different results in a fast and practical way. Its use offers a wealth of advantages and possibilities in the world of architecture and urban planning. One of the fields that benefit is the design of deployable structures, since, by applying this new approach, digital models of this type of structures can be created, at an early stage of their design, on which a large number of checks can be performed without the need to resort to physical models. Throughout this work, this method is applied to create a digital model of one of the deployable structures designed by the architect Emilio Pérez Piñero using the Grasshopper 3D program, and subsequently reproduce its folding-deployment process using the Kangaroo software.

[gl] O deseño paramétrico é unha nova forma de enfocar o deseño na que o deseñador se centra en crear un algoritmo que permítalle explorar varios resultados distintos dunha forma rápida e práctica. O seu emprego ofrece unha gran cantidade de vantaxes e posibilidades no mundo da arquitectura e o urbanismo. Un dos campos que ven beneficiados é o deseño de estruturas despregables, xa que, aplicando este novo enfoque, pódense crear modelos dixitais deste tipo de estruturas, nunha fase inicial do seu deseño, sobre os que realizar gran número de comprobacións sen necesidade de recorrer a maquetas físicas. Ao longo deste traballo, aplícase este método para, mediante o programa Grasshopper 3D, crear un modelo dixital dunha das estruturas despregables ideadas polo arquitecto Emilio Pérez Piñero, e posteriormente reproducir o seu proceso de encartadodespregado empregando o software Kangaroo.
[en] This article collects and organizes the contributions of the three authors in the round table that constituted the opening session of the II National Congress of Environmental Education of Catalonia, held on November 26, 2020 and organized by the Catalan Society of Environmental Education-SCEA.

[gl] Este artigo recolle e organiza as achegas dos tres autores na mesa redonda que constituíu a sesión de apertura do II Congrés Nacional d'Educació Ambiental de Catalunya, celebrada o 26 de novembro de 2020 e organizado pola Societat Catalana d'Educació Ambiental-SCEA.
[en] Goals: To determine the efficiency on the use of virtual reality (VR) in the Occupational Therapist (OT) intervention process for people with visual spatial hemineglect (VSH) after an acquired brain injury (ABI). Also, to find out the degree of satisfaction and experience of the participants regarding the intervention and to detail the role played by the occupational therapist in this type of intervention. Methodology: Mixed research study. Mainly quantitative, through the "Functional Independence Measure and Functional Assessment Measure" (FIM+FAM), the "Motor Activity Log" (MAL) and the "Cuestionario de Expereincia de Juego", complemented with a qualitative part, through semi-structured interviews. A sample of 2 persons with ABI and VSN. Results: Participants have not experienced significant changes in occupational performance following the VR sessions. However, it is a means of intervention that motivates participants while making them feel "useful", as they believe that this type of intervention can have long-term benefits and that they would combine it with their usual therapy. Conclusions: More research is needed on this topic, as there is very little evidence on the subject, and the evidence that does exist does not address occupational performance and independence. On the other hand, the figure of the occupational therapist is crucial for the design of accessible settings and to adapt them particularly for each individual, taking into account their priorities, abilities and needs.

[gl] Obxectivos: Determinar a eficacia do uso das gafas de realidade virtual (RV) no proceso de intervención de Terapia Ocupacional (TO) para persoas con hemineglixencia visoespacial (HVE) tras un evento de dano cerebral adquirido (DCA). Asimesmo, coñecer o grao de satisfacción e experiencia das persoas participantes en canto a intervención desenvolvida e detallar o papel que desempeña o terapeuta ocupacional neste tipo de intervención. Metodoloxía: Estudio de investigación mixto. Maioritariamente cuantitativo, a través da "Functional Independence Measure and Functional Assessment Measure" (FIM+FAM), o "Motor Activity Log" (MAL) e o "Cuestionario de Experiencia del Juego", complementada cunha parte cualitativa, a través de entrevistas semiestruturadas. Mostra de 2 persoas con DCA e HVE. Resultados: Non experimentaron cambios significativos no rendemento ocupacional despois das sesións de RV. Non obstante, esta é un medio de intervención que motiva aos participantes e fai que se sintan "útiles", considerando que este tipo de intervencións poden ter beneficios a longo prazo e que o combinarían coa súa terapia habitual. Conclusións: Precísase máis investigación sobre este tema, xa que hai moi poucas evidencias sobre o mesmo e as que existen non abordan o rendemento ocupacional nin a independencia. O papel do terapeuta ocupacional é fundamental para o deseño de escenarios accesibles para adaptalos especialmente a cada individuo, tendo en conta as súas prioridades, capacidades e necesidades.
[en] Antibiotics have beenthe most revolutionary drugs for decades, being able to cure all kinds of diseases and reducing mortality significantly. However, despite all the advances in its production, its effect has been gradually deteriorating until reaching the current crisis. Antibiotic resistance has become a problema on a global scale, causing 700.000 deaths a year and economics losses in the millions. This crisis derived from various factors such as the overuse of antibiotics by people and the livestock industry, incorrect prescriptions and the lack of research on these antimicrobials. This declina in antibiotics had led to the discovery of a number of alternatives, including the use of bacteriophages (viruses specialized in killing bacterias), to cure infections of multi-resistent bacteria. This treatment presents the safety and efficacy necessary to become our best weapon against bacterias, being the solution to the problema of antibiotics which, as we will see, will still have a place in the fight against microorganisms along with the viruses in mixed treatments.

[gl] Os antibióticos foron desde fai décadas os fármacos máis revolucionarios, sendo capaces de curar todo tipo de enfermedades e reducindo a mortalidade de forma significativa. Sen embargo, a pesar de tódolos avance na súa producción, o se efecto foise deteriorando de forma paulatina ata chegar á crise actual. A resistencia a antibióticos converteuse nun problema a escala global, chegando a causa 700.000 mortes ao ano e pérdidas económicas millonarias. Esta crise deriva de varios factores como o uso excesivo dos antibióticos por parte de persoas e gandeiros, as prescripcións incorrectas e a falta de investigación sobre ditos antimicrobianos. Esta decadencia dos antibióticos motivou o descubrimento dunha serie de alternativas, entre elas o uso de bacteriófagos (virus especializados en matar bacterias), para curar infeccións de bacterias multirresistentes. Este tratamento presenta a seguridade e eficacia necesarias para converterse na nosa mellor arma contra as bacterias, sendo a solución ó problema dos antibióticos que como veremos aínda terán o seu lugar na loita contra contra os microorganismos xunto cos virus nos tratamentos mixtos.