BSC-LT/ACAData huggingface dataset:
[en] Access to safe drinking water is one of the most important goals of the 2030 agenda. In order to make progress in this regard, it is necessary to modernize and adapt the distribution of drinking water so that it reaches more places and of better quality. My project aimed to offer an open-source and modernized alternative to the SCADA that controls the Medusa facility –a mockup of the water distribution system of A Coruña, Spain–, which is dedicated to testing and research in the field of hydraulics. In this way, it would be possible to control the system remotely and in some cases activate an AI that automatically solves errors, facilitating the research process and the control of the installation itself to the civil engineers. After implementing the SCADA and all its use cases, it was found that the new version solves efficiency problems and performs its work better, i.e. it is able to provide more immediate system status, in addition to allowing a more comprehensive control with real-time graphs that measure different aspects of the installation.

[gl] O acceso á auga potable é un dos obxectivos máis importantes da axenda 2030. Para poder facer avances neste aspecto, é necesario modernizar e adaptar a distribución de auga potable de tal maneira que chegue a máis sitios e de mellor calidade. O meu proxecto pretende ofrecer unha alternativa open- source e modernizada ao SCADA que controla a instalación Medusa –unha maqueta do sistema de distribución de auga da Coruña, España–, cuxo obxectivo a facer probas e investigación no ámbito da hidráulica. Desta maneira, poderase controlar o sistema de forma remota e nalgúns casos activar unha IA que solucione erros de forma automática, facilitando aos enxeñeiros de camiños o proceso de investigación e o control da propia instalación. Despois de implementar o SCADA e todos os seus casos de uso, púidose comprobar que a nova versión soluciona problemas de eficiencia e realiza mellor o seu traballo, é dicir é capaz de ofrecer de forma máis inmediata o estado do sistema, ademais de permitir un control máis exhaustivo coas gráficas en tempo real que miden diferentes aspectos da instalación.
[en] The level of attention and assimilation of the concepts of the subject "Financial Operations Analysis" taught at Faculty of Economics and Business (UDC) are not satisfactory. The proposal is based on a methodological change through the combination of the inverted classroom, project-based learning (ABPy) and cooperative groups. A greater assimilation of the subject is sought through the development of metacognitive skills derived from the strategies of the proposed active methodologies. The semester will be divided in two parts: In the first four weeks of the course the teacher explains and proposes exercises on the basic concepts of the subject (financial capital, interest rates, laws of capitalization and discount, concept of income and loan). It is intended to provoke active motivated and critical participation in the classroom through the use of advertising actions (announcements). In the following ten weeks five cooperative groups are created. These should: (1) deepen in the theoretical and practical concepts of the subject, (2) elaborate a conceptual map and digital exercises, as well as (3) create a didactic video of the subject. Each group is raising the subjects created on google classroom, which allows the control of activity. The evaluation is established by competencies. The change? Radical, exciting and motivating...

[gl] O nivel de atención e de asimilación dos conceptos da materia Análise das Operacións Financeiras impartida na Facultade de Economía e Empresa da UDC non son satisfactorios. A proposta reside nun cambio metodolóxico a través da combinación da aula invertida, da aprendizaxe baseada en proxectos (ABPy) e o traballo cooperativo. Búscase unha maior asimilación da materia a través do desenvolvemento de habilidades metacognitivas derivadas das estratexias das metodoloxías activas propostas. O cuadrimestre dividirase en dúas partes: Nas primeiras catro semanas do curso o docente explica e propón exercicios sobre os conceptos básicos da materia (capital financeiro, tipos de xuro, leis de capitalización e desconto, concepto de renda e préstamo). Preténdese provocar a participación activa, motivada e crítica na aula a través do emprego de accións publicitarias (anuncios). Nas seguintes dez semanas procédese a crear cinco grupos cooperativos. Estes deben: (1) afondar nos conceptos teórico-prácticos da materia, (2) elaborar un mapa conceptual e exercicios dixitais, ademais de (3) crear un vídeo didáctico da materia. Cada grupo vai subindo os materias creados ao google classroom, o que permite o control de actividade. A avaliación establécese por competencias. ¿O cambio? Radical, apaixoante e motivador.
[en] The article explores the social and historical background of the educational activities of José Maria Eugénio de Almeida (1811-1872), a prestigious member of the Portuguese economic and political elite of the mid-nineteenth century. The study highlights the context of the international exchange of ideas and Eugénio de Almeida's particular interest in the German state education systems of the period. His fact-finding tours to some of these states laid the groundwork for the process of pedagogical renewal undertaken at Casa Pia de Lisboa, the educational institution he led for nearly fifteen years (1859-1872). The aim of the study is to assess the impact of this foreign 'contact' on the Portuguese education system of the time and to examine the construction of an alternative educational reality (that of Casa Pia de Lisboa) based on a foreign model. In line with Mary S. Morgan's research on models as experimental things, the study reveals the successful transmission of Eugénio de Almeida's foreign innovations with the adaptations and accommodations typical of any context of reception.

[gl] O presente artigo contextualiza a acción educativa dun prestixiado membro da elite económica e política portuguesa de mediados do século XIX - José Maria Eugénio de Almeida (1811-1872). Salientando a circulación internacional do coñecemento, revélase o interese que os sistemas educativos dos Estados alemáns suscitan a Eugénio de Almeida. As viaxes pedagóxicas que realiza a algúns deses Estados alicerzam o proceso de renovación pedagóxica que terá lugar na Casa Pia de Lisboa - institución asistencial que lidera entre 1859 e 1872. No fondo, aquilo que se pretende coñecer é o impacto que ese "contacto" (estranxeiro) ten no sistema existente. Verdadeiramente, o posicionamento conceptual é o de percibir como unha realidade (a da Casa Pia de Lisboa) pensada en función dun referente estranxeiro. Noutras palabras, na liña da investigación de Mary S. Morgan, significa que no contexto de recepción hai acomodación e adaptación do coñecemento. Con todo, a súa integridade non se pon en dúbida.
[en] As we move forward over time the restrictions on ship pollution are becoming more stringent. Actually, to comply with the regulations, the ships are being built propelled with LNG as fuel. The project consists of carrying out the retrofit of the engine of a container ship to pass it to the consumption of LNG and the installation of all the necessary elements to supply the GN to the engine.

[gl] A medida que avanzamos no tempo as restricións respeto a contaminación dos buques é cada vez máis estricta. Na actualidade, para cumprir coa normativa, estanse a construír buques propulsados por GNL como combustible. O proxecto consiste en levar a cabo o retrofit do motor dun buque portacontedores para pásalo a consumir GNL e a instalación de todos os elementos necesarios para o suministro de GN ao motor.
[en] This paper offers an analysis of the reviews and biographies of Emilia Pardo Bazán aimed at children and young people. It begins with a sample of textbooks for 4th grade of GCSE and 1st year of GCE and goes on to focus on informative biographies, both individual and short biographies included in anthologies of women. The aim of this work is to analyze what information is offered to this specific public to approach her life and work, what works are mentioned and what images are used to illustrate her person. In total, 11 materials have been studied and the comparative study not only draws conclusions but also opens doors to new questions or reflections, such as the lack of materials on this author aimed at younger audiences.

[gl] O presente artigo ofrece unha análise das recensións e biografías de Emilia Pardo Bazán dirixidas ao público infantil e xuvenil. O percorrido comeza cunha mostra de libros de texto de 4° de ESO e 1° de Bacharelato e pasa a centrarse nas biografías divulgativas, tanto nas individuais como nas breves inseridas dentro de antoloxías de mulleres. Con este traballo preténdese analizar que informacións se ofrecen a este público concreto para que se acerque á súa vida e obra, que obras se mencionan e que imaxes se utilizan para ilustrar a súa persoa. Son 11 os materiais estudados e da comparativa realizada non só se extraen conclusións, senón que tamén se abren portas a novas cuestións ou reflexións, como a constatación da ausencia de materiais sobre esta autora destinados ao público infantil.
[en] The presence of resistance-associated substitutions (RASs) at NS5A region might compromise the efficacy of Direct Acting Antiviral agents (DAAs). Hepatitis C virus (HCV) resistance at NS5A region is mainly focused on patients with HCV genotypes 1a (G1a) and 3 (G3) with other factors of poor treatment response (i.e. cirrhosis, prior treatment-exposure, or HCV-RNA>800,000 IU/mL). Herein, we evaluated in a Spanish cohort of patients with HCV G1a and G3 the prevalence of RASs at domain I NS5A using population-based sequencing and the impact of RASs on the optimization of current therapeutic strategies. RASs considered as clinically relevant were: M28A/G/T, Q30D/E/H/G/K/L/R, L31M/V/F, H58D and Y93C/H/N/S for G1a and Y93H for G3. A total of 232 patients were included (166 G1a and 66 G3). The overall prevalence of NS5A RASs for G1a and G3 patients was low (5.5%) or null, respectively. A high proportion of patients harbored other factors of poor response. Overall, the rates of patients harboring NS5A RASs in combination with any of the other factors were low and the vast majority of patients (G1a> 94% and G3 100%) could be treated with standard treatments of 12 weeks without ribavirin. Testing NS5A RASs in specific HCV-infected populations (i.e. G1a & G3, cirrhosis, prior treatment experienced, HCV-RNA>800.000 IU/mL) might be useful to optimize current NS5A-based therapies avoiding ribavirin-related toxicities and shortening treatment duration in the majority of patients.

[gl] A presenza de variantes asociadas a resistencia (VAR) na rexión NS5A pode comprometer a eficacia dos antivirais de acción directa (AADs). A resistencia no virus da hepatite C (VHC) está principalmente enfocada en pacientes con VHC e xenotipos 1a (G1a) e 3 (G3) con outros factores de peor resposta (e.g. cirrosis, exposición previa a tratamento, ARN-VHC>800.000 UI/mL). Neste estudo avaliouse, nunha cohorte española de doentes con VHC G1a e G3, a prevalencia de VAR basais no dominio I de NS5A e o seu impacto na optimización das estratexias terapéuticas actuais. As VAR determináronse mediante secuenciación poboacional. Consideráronse como clínicamente relevantes as seguintes VAR: M28A/G/T, Q30D/E/H/G/K/L/R, L31M/V/F, H58D e Y93C/H/N/S para G1a e Y93H para G3. Un total de 232 doentes foron incluidos (166 G1a e 66 G3). A prevalencia de VAR a inhibidores de NS5A para doentes con G1a e G3 foi baixa (5,5%) ou nula, respectivamente. Unha alta proporción de doentes tiñan outros factores de peor resposta asociados. En xeral, o número de doentes que tiñan VAR basais a inhibidores de NS5A en combinación con algún dos outros factores foi baixo e a gran maioría dos doentes (G1a>94% e G3 100%) poderían recibir tratamentos estándar de 12 semanas sen ribavirina. O test de VAR na rexión de NS5A en poboacións específicas con infección por VHC (e.g. G1a & G3, cirrosis, exposición previa a tratamento, ARN-VHC>800.000 UI/mL) pode ser útil para optimizar as estratexias terapéuticas baseadas en inhibidores de NS5A evitando as toxicidades asociadas á ribavirina e acurtando a duración do tratamento na maioría dos doentes.
[en] Heavy metals are important environmental pollutants, often toxic to humans. Despite being a heavy metal, zinc is known to be essential for the development of any species, but it shows very low metabolic absorption. In this work the adsorption effectiveness of the brown seaweed Sargassum muticum is studied as a possible substrate to supply zinc in a controlled way. In addition, the simplicity of the redox chemistry of zinc allows its sorption studies to be used as a model to the biosorption of divalent cations by algae. Different experimental conditions are investigated, such as the effect of pH on the sorption process or the contact time in kinetic studies. The equilibrium of the biosorption is strongly influenced by the pH, reaching the maximum sorption values arround pH 5.5. The kinetics are fast, 80% of the total sorption is achieved in 40 min, and the data are correctly explained by the pseudo second order kinetic model. Equilibrium data are analysed by the Langmuir model and Sargassum muticum shows one of the highest affinities for zinc ions, being greater only for lead and mercury. The determination of zinc was carried out by UV-vis absorption spectroscopy in all the studies; therefore, it was necessary to use a colorimetric agent known as Zincon.

[gl] Os metais pesados son importantes contaminantes do medio ambiente e adoitan ser tóxicos para o ser humano; a pesar de que o zinc forma parte deste grupo, é un metal fundamental para o desenvolvemento de calquera especie, mais presenta moi baixa absorción a nivel metabólico. Neste traballo estúdase a eficacia de adsorción da alga parda Sargassum muticum como posible substrato para subministrar zinc de forma controlada. Ademais, o estudo con este catión serve para modelar o comportamento entre algas e catións divalentes debido á simplicidade da súa química redox. Avalíanse diferentes condicións de traballo como o efecto do pH no proceso de adsorción ou a variación co tempo ao realizarmos estudos cinéticos. Obsérvase que o equilibrio de bioadsorción está moi influenciado polo pH, alcanzando os valores máximos de adsorción a pH arredor de 5.5. As cinéticas son rápidas, un 80% da adsorción total alcanzase en 40 min, e axústanse perfectamente ao modelo cinético de pseudo segunda orde. En canto ás isotermas, analizadas polo modelo de Langmuir, conclúese que a afinidade alga-catión é das máis altas entre todos os metais pesados, sendo unicamente superado polo chumbo e o mercurio. A determinación de zinc no medio levouse a cabo por espectroscopia de absorción UV- vis en todos os estudos; para o que foi necesario usar un axente colorimétrico coñecido como Zincon.
[en] The General Plan of 1967 was born with a clear vocation, to adapt the growth of the city to the new urban legislation that arises under the law of the soil of 1956 and to give a legal framework to the interventions of the state. In the document of Corrales, Molezún and Pagola it will have special relevance the role of the partial planning as model of growth of the city and will be planned architectural, urban planning and of infrastructure projects supported in the necessity of the change of Scale of capital of province to regional metropolis, being for it fundamental the introduction of the metropolitan vision and the densification of the consolidated city. In the Architectural field, the evolution of modernity from tradition will be a fundamental pillar for new professionals who seek greater experimentation rather than conserving a shared language.

[gl] O Plan Xeral de 1967 nace cunha vocación clara, adaptar o crecemento da cidade da Coruña á nova lexislación urbanística que xorde ao amparo da Lei do Solo de 1956 e dar un marco legal ás intervencións do Estado. No documento de Corrales, Molezún e Pagola terá especial relevancia o papel do planeamento parcial como modelo de crecemento da cidade e planificaranse proxectos arquitectónicos, urbanísticos e de infraestruturas sustentados na necesidade do cambio de escala de capital de provincia a metrópole rexional, sendo fundamental a introdución da visión metropolitana e a densificación da cidade consolidada. No ámbito arquitectónico, a evolución da modernidade desde a tradición será un pilar fundamental para os novos profesionais que buscarán unha maior experimentación en lugar de conservar unha linguaxe compartida.
[en] The aim of this project is to analyse two subjects related to sexuality: sexual consent and fidelity, exploring the process of reconstruction and renegotiation in which they are involved nowadays. A qualitative study has been developed targeting a young adult population between 20 and 30 years of age. From a gender-sensitive approach, different meanings that both dimensions acquire in relation to previous generations are identified. The results suggest that both phenomenon are going through a process of social change, due to the opening to new relationship structures and the diversity of sexual practices, in consolidation process, that call into question the emotional bases that have underlined intimate relationships up until now.

[gl] Este traballo de investigación analiza dous fenómenos da sexualidade, o consentimento sexual e a fidelidade, explorando o proceso de reconstrución e renegociación no que se encontran na actualidade. A través dun traballo de campo cualitativo dirixido á xuventude de entre 20 e 30 anos e dende unha perspectiva de xénero, identifícanse os diferentes significados que ambas dimensións adquieren con respecto ás xeracións anteriores. Os resultados amosan que, ambos fenómenos están nun proceso de cambio social debido, fundamentalmente, á apertura a novas fórmulas afectivas e a diversidade de prácticas sexuais, en proceso de consolidación, que cuestionan as bases emocionais nas que se fundamentaran, até o momento actual, as relacións íntimas
[en] Sudden cardiac death due to ventricular fibrillation (VF) during acute myocardial infarction (AMI) is one of the leading causes of mortality worldwide. There are studies that support the presence of a genetic background to VF during AMI, the majority focused on polymorphisms and mutations in genes related to ion channels. In this Master Project the presence of common and rare variants are analysed in 11 genes of the atherosclerosis pathway (ABCA1, ABCC8, ADRB2, AGTR1, AGTR2, AKAP10, ALOX5, ADIPOQ, APOA1, APOE and APOH) of 24 patients, which, 12 are cases (AMI with VF) and 12 controls (AMI without VF). After the bioinformatics analysis, a significant polymorphism, rs429358, was found in the APOE gene, in five patients, that presents a significant association to the development of AMI in absence of VF. On the other hand, three mutations were found: p.Ala2058Gly in the ABCA1 gene, without association to VF, but with a possible role in the development of AMI, p.Asp18Ala in the AKAP10 gene that could have an important function in VF during AMI and c.981+3_981+4insG in ALOX5 which, according to the predictions, would not affect the final conformation of the protein and, therefore, neither the development of AMI nor VF. Additional studies will be required to replicate these analyses with a larger number of patients, and also functional studies to achieve confirmation of the results obtained in this work.

[gl] A Morte Súbita Cardíaca debida á fibrilación ventricular (FV) durante o infarto agudo de miocardio (IAM) é una das principais causas de mortalidade no mundo. Existen estudos que apoian a existencia dunha base xenética que predispón a presentar FV durante o IAM, a maioría centrados en polimorfismos e mutacións en xenes involucrados nos canais iónicos. Neste Traballo de Fin de Máster analízase a presenza de variantes comúns e raras en 11 xenes da vía da aterosclerose (ABCA1, ABCC8, ADRB2, AGTR1, AGTR2, AKAP10, ALOX5, ADIPOQ, APOA1, APOE y APOH) de 24 pacientes, os cales, 12 son casos (IAM con FV) e outros 12 controis (IAM sen FV). Trala análise bioinformática encontrouse un polimorfismo significativo, rs429358, no xene APOE, en cinco pacientes, que presenta asociación significativa ao desenvolvemento do IAM na ausencia de FV. Por outro lado, encontráronse tres mutacións: p.Ala2058Gly no xene ABCA1, sen asociación coa FV, cun posible papel no 2 desenvolvemento do IAM, p.Asp18Ala no xene AKAP10 que podería ter unha función importante na FV durante o IAM e c.981+3_981+4insG en ALOX5 que, segundo as predicións, non afectaría á conformación final da proteína e, polo tanto, tampouco ao desenvolvemento de IAM nin FV. Non só requiriranse estudos adicionais que repliquen estes análises cun maior número de pacientes, senón tamén estudos funcionais para lograr a confirmación dos resultados obtidos neste traballo.
[en] Background: 7 month old child presenting severe caudal regression síndrome. Objectives: Improve positioning and increase range of motion in the lower limbs and stimulate appropriate motor milestone development. Intervention: A 19-week intervention was conducted, with a weekly intensive regimen and a daily duration of 30 minutes. The intervention consisted of a combination of active therapeutic exercises and passive manipulations to achieve the established goals. To assess the results of this intervention, a posture evaluation, range of motion measurements, and evaluation of the patient's active mobility were performed. Additionally, childhood development tests were administered to compare and quantify their pre- and post-intervention abilities. Results: The intervention has resulted in improvement in the observed impairments identified in the diagnosis, as evidenced by measurements of range of motion, motor exploration, and the results of developmental tests. Conclusions: The implementation of this intervention proved to be effective in increasing passive ranges of motion, improving joint positioning, as well as achieving appropriate and patient-specific motor milestones.

[gl] Presentación do caso: neno de 7 meses con síndrome de regresión caudal severo. Obxectivos: Mellorar o posicionamento e aumentar o rango articular de MMII, e estimular o desarrollo axeitado dos hitos motores Intervención: Realizouse una intervención de 19 semanas, cun réxime intensivo semanal, e una duración diaria de 30 minutos. A intervención constou da suma de exercicio terapéutico activo e manipulacións pasivas para alcanzar os obxectivos establecidos. Resultados: A intervención xerou unha melloría das afectacións obxectivadas no diagnóstico, evidenciado nas medición dos rangos articulares, a exploración da motricidade e os resultados dos tests de desarrollo. Conclusións: A realización desta intervención mostrouse efectiva no aumento dos rangos pasivos, a mellora do posicionamento articular, así como da adquisición de hitos motores adecuados e adaptados ao paciente.