[en] This study aims to assess the treatment outcomes (functional and subjective) of full-arch fixed hybrid rehabilitations made of PEEK (poly-ether-ether-ketone) with milled crowns of nano-filled composite (NFC) supported on four to six implants. In this randomized clinical trial, 34 edentate patients in the upper and/or the lower jaws were treated with the fixed hybrid dentures. In 16 patients (47.1% of the sample), the implants were loaded immediately (IL) by means of a provisional fixed rehabilitation made of PMMA (polymethylmethacrylate) screwed on Multi-Unit (MU) abutments connected after emplacement of the implant; however, in the counterparts (n = 18) these MU abutments were covered by healing caps and were left unloaded during two months (conventional loading protocol?CL), when all patients received a fixed hybrid PEEK-NFC rehabilitation on the upper and/or the lower jaw. Treatment outcomes were assessed 12 months after prostheses delivery. Functional outcomes were calculated according to masticatory performance, estimated by mixing ability tests of two colored chewing gums after ten chewing strokes, by the occlusal force/area recorded by pressure-sensitive sheets, and by electromyography of masseters and temporal muscles at maximum biteforce. The subjective outcomes of the treatment were assessed using both the oral satisfaction scale (visual analog scale) and the Spanish version of the Oral Health Impact Profile (OHIP-20). The findings of the present study showed that treatment with fixed PEEK-NFC hybrid prostheses significantly improved the masticatory performance, bite force, occlusal pattern, quality of life, and satisfaction, with the IL group being those with significantly higher occlusal bite forces and greater satisfaction in comparison with CL group. It should be concluded that PEEK-NFC hybrid prostheses can improve several patient-centered outcomes and that loading protocol significantly affects the patient?s self-rated satisfaction.

[es] Este estudio tiene como objetivo evaluar los resultados del tratamiento (funcionales y subjetivos) de rehabilitaciones h?bridas fijas de arco completo hechas de PEEK (poli?ter-?ter-cetona) con coronas fresadas de compuesto nanorelleno (NFC) soportadas sobre cuatro a seis implantes. En este ensayo cl?nico aleatorizado, 34 pacientes desdentados en la mand?bula superior y/o inferior fueron tratados con dentaduras postizas h?bridas fijas. En 16 pacientes (47,1% de la muestra), los implantes fueron cargados inmediatamente (IL) mediante una rehabilitaci?n fija provisional de PMMA (polimetilmetacrilato) atornillada sobre pilares Multi-Unit (MU) conectados tras la colocaci?n del implante; sin embargo, en las contrapartes (n = 18) estos pilares MU se cubrieron con cofias de cicatrizaci?n y se dejaron sin carga durante dos meses (protocolo de carga convencional-CL), cuando todos los pacientes recibieron una rehabilitaci?n h?brida fija de PEEK-NFC en la parte superior y/o la mand?bula inferior. Los resultados del tratamiento se evaluaron 12 meses despu?s de la entrega de las pr?tesis. Los resultados funcionales se calcularon de acuerdo con el rendimiento masticatorio, estimado mediante pruebas de capacidad de mezcla de dos chicles de colores despu?s de diez golpes de masticaci?n, por la fuerza/?rea oclusal registrada por l?minas sensibles a la presi?n y por electromiograf?a de los m?sculos maseteros y temporales con la fuerza de mordida m?xima. Los resultados subjetivos del tratamiento se evaluaron utilizando tanto la escala de satisfacci?n oral (escala visual anal?gica) como la versi?n espa?ola del Oral Health Impact Profile (OHIP-20). Los hallazgos del presente estudio mostraron que el tratamiento con pr?tesis h?bridas fijas de PEEK-NFC mejor? significativamente el rendimiento masticatorio, la fuerza de mordida, el patr?n oclusal, la calidad de vida y la satisfacci?n, siendo el grupo IL los que presentaron fuerzas de mordida oclusal significativamente mayores y mayor satisfacci?n. en comparaci?n con el grupo CL. Se debe concluir que las pr?tesis h?bridas PEEK-NFC pueden mejorar varios resultados centrados en el paciente y que el protocolo de carga afecta significativamente la satisfacci?n autocalificada del paciente.