[en] Introduction. Multiple Sclerosis (MS) is the most prevalent chronic neurodegenerative disease of central nervous system. It is inflammatory in nature, causing muscle loss and possibly fat gain, which, in the abdominal area, could be related to the high production of proinflammatory cytokines such as Interleukin-6 (IL-6). Objectives. Establish the relationship between abdominal fat, inflammatory level and anthropometric measurements in MS patients, by establishing the percentage of abdominal obesity, anthropometric measurements (waist perimeter, WtHR, BMI and %FM), serum levels of IL-6, compare IL-6 and anthropometry in patients with and without abdominal obesity, and correlate IL-6 with anthropometry. Material and methods. It has been done a descriptive, analytical, quantitative and cross-sectional study in which have participated 57 patients with MS. Blood samples were analysed with ELISA technique (R&D Systems), and it has been taken anthropometric measurements with a portable clinical scale SECA model, a stadiometer model SECA 220 Hamburg, Germany, and an inextensible and narrow anthropometric tape model Lufkin W606PM. Results. An 87.7% of 57 patients suffer abdominal obesity and their inflammation and anthropometric measurements are higher than people without (12.3%): IL-6 (3.79pg/ml vs 1.77pg/ml), waist perimeter (97.53cm vs 80.90cm), WtHR (0.59 vs 0.47), BMI (28.54 kg/m2 vs 22.87 kg/m2) and %FM (21.53% vs 16.68%). In addition, IL-6 values correlate positively (p-value <0.05) with the waist perimeter (0.028) and WtHR (0.026), but not with BMI (0.152) and %FM (0.135). Conclusions. There is a positive correlation between the abdominal fat level, inflammation level, waist perimeter and the WtHR in MS patients.

[es] Introducción. La Esclerosis Múltiple (EM) es la enfermedad crónica neurodegenerativa del sistema nervioso central más prevalente. Es de naturaleza inflamatoria, cursando con pérdida muscular y con ganancia de grasa que, de ser abdominal, podría relacionarse con el aumento de citoquinas proinflamatorias como la Interleuquina-6. Objetivos. Establecer la relación entre grasa abdominal, nivel de inflamación y valores antropométricos en pacientes con EM, determinando el porcentaje de obesidad abdominal, variables antropométricas (perímetro de la cintura, ÍCT, ÍMC y %MG), niveles séricos de IL-6, comparando IL-6 y antropometría en pacientes con y sin obesidad abdominal y correlacionando IL-6 con antropometría. Material y métodos. Se ha realizado un estudio descriptivo, analítico, cuantitativo y transversal con 57 pacientes con EM. Las muestras sanguíneas se analizaron mediante técnica ELISA (R&D Systems), y se tomaron medidas antropométricas con una báscula modelo SECA, un tallímetro modelo SECA 220 Hamburg, Germany y un metro estrecho y metálico extensible modelo Lufkin W606PM. Resultados. Un 87.7% de los 57 pacientes sufren obesidad abdominal y sus valores de inflamación y antropométricos son mayores que los que no la sufren (12.3%): IL-6 (3.79pg/ml vs 1.77pg/ml), perímetro cintura (97.53cm vs 80.90cm), ÍCT (0.59 vs 0.47), ÍMC (28.54 kg/m2 vs 22.87kg/m2) y %MG (21.53% vs 16.68%). Además, los valores de IL-6 se correlacionan positivamente (p-valor<0.05) con perímetro cintura (0.028) e ÍCT (0.026), pero no con ÍMC (0.152) y %MG (0.135). Conclusiones. Existe una correlación positiva entre el nivel de grasa abdominal, el de inflamación, el perímetro de cintura y el ÍCT en pacientes con EM.