[en] Knowing treatment outcome is essential for tuberculosis (TB) control, although in Spain this information is not collected in all the cases reported. Moreover, cases registry has shown a noticeable underreporting.Two analytical cohort studies were designed to achieve the objectives of the research; the first one was a retrospective study (2000-2004) and the second one prospective (2005-2007). TB cases of any location from Health Area of Salamanca (Hospital Care) were analyzed -321 and 108 patients, respectively-. Information from clinical record was complemented by a clinical interview to the patient in the prospective series. The statistical information processing was conducted with Statistical Package for the Social Sciences (SPSS) program.The most important conclusions were as follows: 1. The TB incidence rates estimated in this study were higher than those reflected in Enfermedades de Declaraci?n Obligatoria registration (system of notifiable diseases).2. The level of satisfactory outcomes (SO) -39.6% in retrospective study and 55.6% in prospective one- should be improved, especially taking into account the transmissible nature of the disease.3. The proportion of potentially unsatisfactory outcomes (PUO) -52.3% in retrospective study and 40.7% in prospective one- was very high and was mainly conditioned by the losses. 4. Institutionalization and infection by human immunodeficiency virus (HIV) were the variables included in the final model obtained by logistic regression in the retrospective study. Being adult (25-64 years), suffering comorbidity and having at least one social risk factor (SRF) were the variables correlated with PUO for automatic method in the prospective series; being mature adult (55-64 years), comorbidity, SRF and disorder in patient s routine were also included using the manual method.5. Ages higher than 84 years and comorbidity predicted deaths in the retrospective investigation, while outcome was correlated with the institutional conditions in the prospective one.

[es] Aunque conocer el resultado del tratamiento es esencial para el control de la tuberculosis (TB), en Espa?a esta informaci?n no se recoge en la totalidad de los casos notificados. Adem?s, tal registro de casos ha revelado una notoria subdeclaraci?n.Para lograr los objetivos de la investigaci?n, se dise?aron dos estudios anal?ticos de cohortes, el primero retrospectivo (2000-2004) y el segundo prospectivo (2005-2007). Se analizaron los casos de TB de cualquier localizaci?n de la Atenci?n Hospitalaria del ?rea de Salud de Salamanca -321 y 108 pacientes, respectivamente-. En la serie prospectiva, la informaci?n de la historia cl?nica se complement? con una entrevista cl?nica al paciente. El tratamiento estad?stico de la informaci?n se realiz? con el programa Statistical Package for the Social Sciences (SPSS).Conclusiones m?s relevantes:1.Las tasas de incidencia de TB estimadas en este trabajo fueron superiores a las que reflejaba el sistema de Enfermedades de Declaraci?n Obligatoria (EDO).2.El nivel de resultados satisfactorios (RS) -39,6% en estudio retrospectivo y 55,6% en prospectivo- debe ser mejorado, sobre todo teniendo en cuenta la naturaleza transmisible de la enfermedad.3.La proporci?n de resultados potencialmente insatisfactorios (RPI) -52,3% en trabajo retrospectivo y 40,7% en prospectivo- fue muy alta y estuvo fundamentalmente condicionada por las p?rdidas.4.En la regresi?n log?stica, institucionalizaci?n e infecci?n por virus de la inmunodeficiencia humana (VIH) fueron las variables incluidas en el modelo final para los RPI en la serie retrospectiva. En la prospectiva, ser adulto (25-64 a?os), padecer comorbilidad y presentar al menos un factor social de riesgo (FSR) se correlacionaron con los RPI por el procedimiento autom?tico, y ser adulto maduro (55-64 a?os), comorbilidad, FSR y trastorno en la rutina del enfermo lo hicieron aplicando el m?todo manual.5.Las edades superiores a los 84 a?os y la comorbilidad predijeron los fallecimientos en la investigaci?n retrospectiva, mientras que en la prospectiva ese desenlace se correlacion? con las condiciones institucionales.