BSC-LT/ACAData huggingface dataset:
[en] Infantile haemangioma is a bening vascular tumor affecting 3-10% of infants. It shows a characteristic natural development, with a rapid growth phase during the first months of life, followed by stabilization and spontaneous involution until its demise throughout 5-7 years. However there could be residual telangiectasis or fibrofatty lesions instead. Since 2008, propranolol became the first-line treatment in these patients, which was administered as compassionate treatment being not formally defined indications in this pathology. Ever since, patients controlled at the pediatric vascular anomalies consultation in the University Hospital Complex of A Coruña, have received such treatment. We retrospectively analyzed data present in the medical record, together with photographic material taken from patients with infantile haemangioma controlled at the pediatric vascular anomalies consultation, that have been treated with propranolol from 2009 to 2014. We also gathered data from patients who, during that period, failed to be treated with propranolol. Most of infantile haemangiomas are found in girls, are superficial and with a focal distribution, being the head its most common location. There is a high rate of prematurity and low birth weight. The most usual complication is ulceration. We suggest adose of 1 mg / kg / 24 hours of propranolol taken in two divided doses for 8- 10 months as effective in the treatment of infantile haemangioma with few side effects, where the most important variable in the treatment is the age at onset.

[gl] O hemanxioma infantil é un tumor vascular que afecta ao 3-10 % dos nenos. Ten unha historia natural característica, cunha fase de rápido crecemento durante o primeiro ano de vida, logo dunha estabilización e involución ata á súa desaparición ao longo dos 5-7 anos. Poden quedar restos residuáis como telangiectasias ou lesión fibroadiposa. Dende 2008, comezouse a usar de maneira compaixiva o propranolol como trata mento de primeira liña nestes doentes. Dende entón, nenos controlados na consulta de anomalías vasculares pediátrica do Complexo Hospitalario Universitario de A Coruña recibiron este tratamento. Realizamos un estudo retrospectivo cos datos presentes na ficha médica, así como material fotográfico de doentes con hemanxioma infantil controlados na consulta de anomalías que foron tratados con propranolol entre 2009 e 2014. Recollemos tamén os datos de doentes que, durante ese período, non foron tratados con propranolol. Notamos que a maioría dos hemanxiomas infantís atópanse nas nenas, son de distribución focal e superficiaís. A localización máis común é a cabeza. Hai un ha alta taxa de prematuridade e baixo peso ó nacemento. A complicación máis común é a ulceracion. Vimos que unha dose de 1 mg / kg / 24 horas de propranolol en dúas tomas durante 8-10 meses foi eficaz no tratamento do hemanxioma infantil con poucos efectos secundarios, onde a variable máis importante do trata mento é a idade de inicio do mesmo.
[en] The high content in nutraceutical compounds is common to all varieties of Capsicum annum (L.), both traditional and commercial ones. For this work, we analysed ten traditional varieties from different areas of the Mediterranean region and three commercial varieties. Analyses of the soluble solids content, pH, titratable acidity, ascorbic acid, phenols, and antioxidant capacity were carried out. The results manifested in a high correlation between the antioxidant capacity and the content of phenols and ascorbic acid, presenting variations in its content depending on the variety studied.

[gl] O alto contido en compostos nutracéuticos é común para todas as variedades de Capsicum annum (L.), tanto en variedades tradicionais como comerciais. Para este traballo analizáronse dez variedades tradicionais de pementos procedentes de diferentes rexións da rexión Mediterránea e tres variedades comerciais. Leváronse a cabo análisis de contido en sólidos solubles, pH, acidez valorable, ácido ascórbico, fenoles e capacidade antioxidante. Os resultados manifestaron unha alta correlación entre a capacidade antioxidante e o contido en fenoles e ácido ascórbico, presentando variacións no seu contido en función da variedade estudada.
[en] Loss of gap junction intercellular communication (GJIC) and/or downregulation of connexins (Cxs) have been reported in different cancer types ncluding melanoma. Cxs have been described as tumor suppressors in earlier stages of melanoma. However during tumor cell invasion and metastasis their role is still controversial. Extracellular vesicles (EVs) and exosomes released by cells participate in cell communication and can be involved in tumor progression. The transmembrane protein connexin43 (Cx43) was found in exosomas and participate in the transfer of information to the target cell though gap junctions (GJs). The aim of this work was to study the role of the Cx43 in exosomas in melanoma progression. Cx43 was only present in exosomes derived from melanoma cells expressing ectopic Cx43 (A375-vCx43). When different melanoma cell lines were exposed to exosomal Cx43, these vesicles decreased cell proliferation and blocked colonies grown. The analysis of protein content of the exosomes positive and negative for Cx43 was carried out by mass spectrometry. Our results indicated that exosomal Cx43 through its scaffolding function may be involved in the recruitment of proteins and other molecules to the exosomes switching the role of these EVs in melanoma progression. Further understanding of the role of Cx43 in the exosomes will have important implications in order to combat metastasis in melanoma.

[gl] Sábese que a perda da comunicación intercelular mediante unións comunicantes (UCs) e/ou a regulación negativa das conexinas (Cxs), dáse en diferentes tipos de cancro, incluído o melanoma. As Cxs describíronse como supresores tumorales en estadíos temperás do melanoma. Namentres, durante a invasión das células tumorales e a metástase, o seu papel é controvertido. As vesículas extracelulares e os exosomas liberados polas células, participan na comunicación celular e poden participar na progresión tumoral. A proteína transmembrana conexina 43 (Cx43) foi atopada nos exosomas e participa na transferencia de información á célula diana a través de UCs. O obxetivo principal deste traballo foi coñecer o papel da Cx43 presente nos exosomas de liñas de melanoma durante a progresión tumoral. Os resultados amosaron que a Cx43 só estaba presente nos exosomas derivados das células de melanoma con expresión ectópica para a Cx43 (A375-vCx43). Cando se expuxeron diferentes liñas celulares de melanoma á Cx43 exosomal, estas vesículas diminuíron a proliferación celular e o crecemento de colonias. A análise das proteínas presentes nos exosomas das liñas positiva e negativa para a Cx43 mediante espectometría de masas indicou que a Cx43 a nivel exosomal a través da súa función de andamio podería estar implicada no recrutamento de proteínas e outros compostos cara os exosomas, cambiando o seu papel no progreso do melanoma. Unha maior comprensión do papel da Cx43 nos exosomas terá implicacións para o desenvolvemento de novas estratexias terapéuticas para combater a metástase no melanoma.
[en] One of the problems facing editors of secular Galician-Portuguese lyric poetry is the misreading or misinterpretation of certain forms and sections due to an imperfect process of manuscript transmission. As an illustration of this, as well as the challenges faced by editors trying to create a sound and accurate reconstruction of the original text, this article will examine the apparent variation between the words perdon and pardon in the Galician-Portuguese cantiga manuscripts transmitted in Italian apographs. This comprehensive analysis of the occurrence of pardon in the corpus of secular Galician-Portuguese troubadour poetry demonstrates that the presence of the alternative form is due, not to variation, but to an inexact rendering on the part of a scribe in Cancioneiro da Biblioteca Nacional. A similar need for emendation is also revealed in relation to other false variant forms introduced by the same scribe and reproduced uncritically in most subsequent editions (perfiar / parfiar, per / par).

[gl] No marco dos problemas editoriais que presenta o texto das cantigas profanas galego-portuguesas por causa dun proceso de transmisión textual que dificulta a lectura ou interpretación dalgunhas formas ou pasaxes, neste artigo estúdase unha cuestión lingüístico-editorial de importancia para unha correcta e criteriosa fixación textual do corpus trobadoresco profano: a aparente variación perdon ~ pardon que se detecta en cantigas transmitidas polos apógrafos italianos. Após a revisión exhaustiva das ocorrencias de pardon nos manuscritos, conclúese que é produto dunha deficiente interpretación do copista a do Cancioneiro da Biblioteca Nacional. Do mesmo xeito, esta constatación permite facer algunhas outras emendas textuais de falsas formas e/ou variantes (perfiar / parfiar, per / par) en cantigas copiadas pola mesma man e que os editores, en xeral, mantiveron acriticamente.
[en] The present study is dedicated to the synthesis and structural characterization of eight compounds with potential phytosanitary activity: two semicarbazones and two thiosemicarbazones derived from 2-acetylpyridine, as well as their respective complexes derived from zinc(II). Semicarbazones L1 and L2, and thiosemicarbazones L3 and L4, were synthesized by condensation by heating under reflux in ethanol of 2-acetylpyridine with the corresponding semicarbazides and two thiosemicarbazides, respectively. The ligands L1, L2, L3 and L4 reacted with zinc acetate dihydrate under similar conditions in order to form the coordination compounds C1, C2, C3 and C4. The semicarbazone and thiosemicarbazone ligands behave as [N,N,O] and [N,N,S] tridentate chelates respectively. The synthesized compounds were characterized by 1H and 13C-{1H} NMR spectroscopy, mass spectrometry, IR spectroscopy and molar conductivity measurements.

[gl] O presente traballo comprende a síntese e a caracterización estrutural de oito compostos con potencial actividade fitosanitaria: dúas semicarbazonas e dúas tiosemicarbazonas derivadas da 2-acetilpiridina, así coma os seus respectivos complexos derivados de zinc(II). As semicarbazonas L1 e L2, e as tiosemicarbazonas L3 e L4 foron sintetizadas mediante a condensación en etanol, baixo quentamento con refluxo, de 2-acetilpiridina coas correspondentes semicarbazidas e tiosemicarbazidas, respectivamente. Os ligandos L1, L2, L3 e L4 se fixeron reaccionar con acetato de zinc dihidratado nas mesmas condicións co fin de formar os compostos de coordinación C1, C2, C3 e C4. Os ligandos semicarbazona e tiosemicarbazona se comportan, respectivamente, coma quelatos tridentados [N,N,O] y [N,N,S]. A caracterización dos diferentes compostos sintetizados foi realizada mediante as técnicas de espectroscopía de RMN de 1H e 13C-{1H}, espectrometría de masas, espectroscopía de IR e medidas de conductividade molar.
[en] In this Master's Dissertation, a computer tool has been developed for designing and assessing the sustainability of the concrete structure of an industrial building. On the other hand, using that tool as a base, the student has proceeded to optimise the sustainability of a structure with 26 m span portals. The tool is divided into three parts. The first one allows estimating the building loads, as well as designing the several structural elements of the building: purlins, beams, columns and footings. The second part, interconnected with the previous one, accounts for all materials employed in the structure, and performs its environmental, social and economic Life Cycle Analysis (LCA). It then calculates a global, structural sustainability index, applying the MIVES (Integrated Value Method for Sustainable Assessments, in translation) multi-criteria method. The sustainability model is new and has been developed specifically for this Master's Dissertation. It is a model that, for the purposes of environmental LCA, complies with the EN 15804 standard on sustainability in construction. In addition, the parameters of the model have been configured in such a way as to allow, in the future, sustainability comparisons between structures built with different materials, including also steel and wood. The purpose of the third part of the tool is to obtain a structure with the highest possible sustainability index. This has been done using a genetic algorithms optimization software.

[gl] No presente Traballo Fin de Máster (TFM) elaborouse unha ferramenta informática de cálculo e dimensionamento da estrutura de formigón dunha nave industrial, que tamén serve para avaliar a súa sustentabilidade. Doutra banda, usando como base dita ferramenta, procedeuse á optimización da sustentabilidade dunha estrutura con pórticos de 26 m de luz. A ferramenta de cálculo divídese en tres partes. A primeira permite a estimación de cargas sobre o edificio, así como o cálculo, dimensionamento e armado dos distintos elementos estruturais da nave: correas, vigas, columnas e zapatas. A segunda parte, interconectada coa anterior, contabiliza todos os materiais empregados na estrutura e realiza unha Análise de Ciclo de Vida (ACV) ambiental, social e económico da mesma. Tras iso calcula un índice global de sustentabilidade da estrutura, aplicando o método multicriterio MIVES (Método Integrado de Valor para Avaliacións Sustentables). O modelo de sustentabilidade empregado é novo e desenvolveuse especificamente para este TFM. Trátase dun modelo que, para os efectos do ACV ambiental, cumpre a normativa EN 15804 sobre sustentabilidade en construción. Ademais, os parámetros do modelo configuráronse de tal forma que permita, no futuro, realizar comparacións de sustentabilidade entre estruturas de nave industrial construídas con diferentes materiais, incluíndo tamén o aceiro e a madeira. A terceira parte da ferramenta ten como misión obter unha estrutura co máximo índice de sustentabilidade que resulte posible. Isto fíxose empregando unha aplicación informática de optimización mediante algoritmos xenéticos.
[en] Clinical trials are crucial for validating new medical treatments, such as drugs and surgical procedures, by providing empirical evidence of their efficacy. However, these trials are costly, time-consuming, and often encounter challenges during patient recruitment. Automated methods offer advantages by reducing the manual review of medical records, expand- ing the pool of potential participants, and identifying eligible candidates. The TREC Clinical Trial track addresses this by proposing a patient-trial selection paradigm aimed at streamlining recruitment through the matching of patient and trial descriptions. This project evaluates various Information Retrieval and Natural Language Processing approaches to this process, focusing on the effectiveness of different models in improving clinical trial recruitment.

[gl] Os ensaios clínicos son cruciais para validar novos tratamentos médicos, como fármacos e procedementos cirúrxicos, achegando probas empíricas da súa eficacia. Con todo, estes ensaios son custosos, requiren moito tempo e teñen dificultades á hora de recrutar pacientes. Os métodos automatizados ofrecen vantaxes ao reducir a revisión manual de historiais médicos, ampliar o grupo de posibles participantes e identificar os candidatos elixibles. A tarefa Clinical Trial proposta polo TREC aborda esta cuestión propoñendo un paradigma de selección de pacientes e ensaios destinado a axilizar o recrutamento mediante o emparellamento de descricións de pacientes e ensaios. Este proxecto avalía varios enfoques de Recuperación de Información e Procesamento da Linguaxe Natural para este proceso, centrándose na eficacia de diferentes modelos para mellorar o recrutamento de ensaios clínicos.
[en] Introduction: Child maltreatment is a problem in our society. The nursing community is in continuous contact with the children, for this they have a privileged position for the detection and intervention to these cases. The complexity maltreatment situation can generate uncertainty in the health professional when it is time to tackle it. The clinical practice guidelines and the protocol provide orientation in clinical practice faced with assistance problem like that. Our objective is to know the existence and quality of clinical practice guidelines and the protocol that address child maltreatment and know the role of nursing in them. Methodology: Performed a search for March and April 2018 in the following databases: PubMed, Cinhal, Tripdatabase, Virtual Health Library and Google. The variables analyzed were production and nursing clinics. In a guide where the nursing community is present, I use as a tool of methodological quality, AGREEMENT II. Results: We locate 36 documents. All of them, a 58,33% are updated. In them, the nursing is referring in low number (50%), and in the big mayority takes a secondary role, even though can be a determining factor in the detection of child maltreatment. Regarding the quality of the clinical practice guidelines, it should be pointed out that a scarcity of applicability and rigor in the elaboration in a large part of the clinical practice guidelines analyzed.

[gl] Introdución: O maltrato infantil é un problema na nosa sociedade. Os profesionais de enfermaría encóntranse en contacto continuo con nenos, o que os situa nunha posición privilexiada para a detección e intervención de casos de maltrato. A complexidade dunha situación de maltrato infantil pode xerar inseguridade nos profesionais sanitarios a hora de abordalo. As guías de práctica clínica e protocolos ofrecen orientación na práctica clínica ante un problema asistencial coma este. O noso obxectivo é coñecer a existencia e calidade de guías de práctica clínica e protocolos que aborden o maltrato infantil e coñecer o rol da enfermaría neles. Metodoloxía: Realizamos a búsqueda durante marzo e abril do 2018 nas seguintes bases de datos: PubMed, Cinhal, Tripdatabase, Biblioteca Virtual en Salud e Google. As variables analizadas foron de produción e clínicas de enfermería. Naquelas guías de práctica clínica onde o colectivo de enfermaría está presente utilizamos como ferramenta de calidade metodolóxica, AGREE II. Resultados: Localizamos un total de 36 documentos, dos cales, un 58,33% están actualizados. Neles, a enfermaría é nomeada nun baixo número (50%), e na súa gran maioría tomando un papel secundario, a pesar de que pode ser un factor determinante na detección do maltrato infantil. En canto a calidade das guías de práctica clínica, destaca unha carencia en canto a aplicabilidade e o rigor na elaboración en gran parte das guías analizadas.
[en] This article incites reflection related to the constituent discourses of the canon and the imaginary reader, whose influence seem to determine the reading process by denying non-normative sexualities and reinforcing the hegemonic thought established in values such as heterosexuality, monogamy and monosexuality. In a genre such a poetry, which needs an active readership, the interpretation of texts from the point of view of sexuality presents datum which seem essential to pay attention to regarding the mechanisms that operate and determine the act of reading in an unconscious manner. Although Barthes had announced the death of the author, we detect biographical fingerprints pending analysis with the objective of making visible the plurality and diversity inherent to the poetic word

[gl] Este artigo convida á reflexión arredor dos discursos constituíntes do canon e o imaxinario lector, cuxa influencia semella condicionar o proceso de lectura negando sexualidades non-normativas e reforzando un pensamento hexemónico asentado en valores tales como a heterosexualidade, a monogamia e a monosexualidade. Nun xénero como o poético, necesitado dun lectorado activo, a interpretación dos textos desde o punto de vista da sexualidade ofrece datos aos que cómpre atender sobre os mecanismos que operan e condicionan de maneira inconsciente o acto de lectura. Embora Barthes anunciara a morte da autoría, descóbrense pegadas biográficas pendentes de análise co obxectivo de visibilizar a pluralidade e diversidade propias da palabra poética.
[en] Industrial tourism responds to an emerging phenomenon relating to tourism activity surrounding industries that are still operating, with tours and visits designed to provide visitors with an insight into production processes. It also includes visits to sites with a long-standing industrial tradition that have fallen into disuse and which have been reopened for tourists. In both cases the visit hinges on technologies and know-how, as well as the industrial buildings and sites themselves, considering social and economic cycles and the aesthetics generated by industrialisation or the ultimate loss of production activity. Territory plays a vital role in that it provides a setting for the various phases of the Industrial Revolution, marked by successive periods of transformation and decline, generating heritage-related remains and landmarks that are direct witnesses to a considerable material legacy

[gl] O concepto de turismo industrial explica un fenómeno emerxente referido ás prácticas turísticas xurdidas ao redor das industrias aínda en activo, con visitas que pretenden aproximar o visitante aos procesos técnicos de produción, ou aos lugares de tradición histórica con instalacións que abandonaron hai tempo a actividade e se reabriron para o turismo. En ambos os casos a experiencia persoal da visita xira á volta das tecnoloxías e o saber facer, os edificios e os lugares industriais, as etapas económicas e sociais e a estética que crea a industrialización ou a perda definitiva da produción. Os territorios xogan un papel moi importante por seren o marco das distintas fases da Revolución Industrial, con sucesivas transformacións e declives que xeran vestixios e fitos patrimoniais que son testemuñas directas dun importante legado material.
[en] Multicultural crewing management is a topic more and more important in the maritime industry bussines management plans. This phenomenon is due to the direct link betwen crewing management and índices of occurence. More and more often seafarers face cases where they live together with more tan two different nationalities, international organizations have already taken action on this matter through legal provisions about multicultural awareness training. This paper propose a studio about how national culture afects to the indididual personally, current multicultural crewing management, problems and potential solutions.

[gl] A xestión de tripulacións multiculturais é un asunto que cobra cada vez máis importancia nos plans de dirección empresarial da industria marítima. Este fenómeno débese a relación directa que ten na accidentalidade. Cada vez son máis os casos onde os mariños conviven con máis de duas nacionalidades diferentes, as organización internacionais xa comenzaron a tomar cartas no asunto mediante disposicións legais sobre a formación en conciencia multicultural. Este proyecto propón un estudio acerca de cómo a cultura nacional afecta o individuo persoalmente, situación actual da xestión de tripulacións multiculturais, problemática e posibles solucións.