September 79, 1929.

Dear Dr. md Mrs. `Forkmr,

              Your cnrd with the lovely Freiburg Cathedral, :Aich I love so
-a St-a& on my desk a oonetxnt reminder of where you Care and you letter wae moot,
wslcomQ.  It quite took me back to the days long before the war when 1 waS there too.
The &yin& of m-terials for tkre laboratory was in my day too;  I remmember buying all
my own glassw~6, alooBOf znd everything, both there <and in Leipzig.   Y.Ioesn*t it
make you realiae haz free everything is hers.

    ?e xre in our ne@ quqrters and they are not as bad as my fancy painted t&g,
but they nre not as #ce as o3.A old rooms.   ?%e boys th?t thnt its easier to do the sv(l
work in them,  but they zre so muOh rxore dirty that they have to spenti a lot of time
cleaning up. "3. $'linn worked vep: h-.rd On th%m aild R'PdS them #Wt a$ nice as pOS&
ble so that the only foula zre the lnck of sunshine r?nd the noi& and dirt of tha
new bufldings.   The new InstSutcs Xo~th Buildiq is all up in skzeleton foml rnd
all the rivlting :aas done durin;= the summ8r.  The Cornell Buildings are still awaiting
six months of blasting whiti now drives m&St nrg ?xucocyte off 42x3 field.

   38 went right to wWk on tile -gapers czl.1 semn of them.    The one on the
giant cells in the blood s8ems to me all ready ns it is and very nice indeed,  I think
that it will $o in f9ith your n,ams alone;  Br. llhan e&rees <and that S88ms to be 2 good
WCJ t0 settP% that mRtt8r;   the other giant cell pper seems to !ne a little thin&
I think th.3.t ';lr. Docan would l&e to do some r8writing on that one.   rye wil2'both
aoz% over it and send you a cmbon before ne Submit it for putilication.   2heth8r we
shall get one or both colored plnter I do not yet Imow.   The work smm to ne very fins
to settle the problem ar,d to ex+ain all the transitions of section8 50 that I
greatly hop8 for the two colored plntes.   I have hnd one tn.1:~ with Ihr. Flexner about
it ur@g their yablicnt ion.  Ii8 has 2md lo&5 of complications over papers this
mS5sner and his problem is to Satisfy ovaryone or as n?,:rly as T>ossibbe so \7e can only
wait and ~8.

    Of the other five papers,  four are practically ready; the tirst the phosphatkl
is all ready;  the ssoond the fatty acids all but the final copy.   The third 191s
controls needs a lot of re-qritfn&  It to0 WQS much tO0 thin ,ana not logically
written:   In or&r ti even the length I had to tranefer all the disou$eidn to this
third paper;  the rewriting is to put some logic intt, the story of the controls.
Ve had planned a$ you retmm8mber to try 12 doses of dead tubercle bacilli in the
amount quaivalent to the phos&&id.   Tie ehall not do it for the first dose
kills the rabbits.  Too much protein involve&   'Yaentt that interesting ? The
WB tri8d half the Bose and that killed too but it wasn't a clean experiment for there
was a nick in the wall of the intestine but on the under side.    This w88k oqht
to 8ee the finish of all' five of the papers.   The first three are to go in one number
of the journal if they are accepted and Dr. Rous thinks that ti?sre ~7111 be no trouble.
Then next we8k w8 shall start on ths giant cell'pa:>ers ?nd &ive them th8 final
rkvisibnn, as I said above, Gractiallg limiting any additions to the general on8.

  ' Dr. Deans work this tnmner was Q gr nt ins;?iration to hip, and a great gain to
the depmt'-:mnt.  Ha cazte '&CM& quite content win.   Petroff has tisociatad all thrree
stasins into R virulent 2nd avirulent stran.   The avirulent form hzxl morelipoid
axI is more acid f,ast .znd mare like the ty$cal fo~ns mor;l!hologicnlly.   The virulent
one in some prelimin?,r;y tests he ~4. Toan mF.de more like a septicemia.   Ge 2re going


after it hot foot.  It modifi8s OUr PlZnS PrOfOtUKlly.   f t seem to m8 that it BIOW
is ;&ssible to repeat our sqaration of toxic protein ndnd tissue-forming li;>oid
action witch these two living forms.   Cur bovine B 1 strain naS perhaps 90 $
&he avirulent form abd 10;; virulent type.   The pzrt of Petroffs work given last
spring at the meetings has been publisherd in the Amer. Rev of TB.   ??hiS nBw8r
idea not.   Es is 8war to co-operate with us .and we are now innoculnti~ only
from pure colonies.`  ti. B&n is also to work with theSe disociatied straine.
Dr. Chit8 iS to come to See us 800n*  Just How he mill react I cm not quite surb,
but I am convincsd that Retroffto work makes the n&t hopeful step.

  ?3r. l?ieeman, the new man from Indienopolis is fine.  Yhils he was waiting
around for us to &ad pnpem5 hs de.cided to play with the crg&als nnd ha8 provea
vex-y nicely that they care on the slide before me put the drop of blood on. They
&re either from an imgurity in the brtrhromstte or from the Bew York tap water.
Nei'Llslber@r says that the Eew York water has lots of calcium.   ftn't th,at rather of
a jok8 on us,   Par his own problem he is to study inJections of embryonic
tissue juice into t,he peritoneum followed'by embryohic liver *and other things that
ueem hopeful to study the primitive cells and &her rextions,   I ,m are that he wili
work well.  T: hm?i planned for him to work on the pigeone,  but 3r. Doan will not be
ready to start them for too long.

Dr. Miller has not yet c-me;  he is to be here about the f irot of B&?m8ber.

   DrJ Swift'0  dep,artment is to be int8r@sted in the supravital through
Dr. l&tJwen who worked with Wsh#@o warm bojt all summr.  Dr. River8 has a new man
coming who is-to fol:ottr the blood in measrls with the sugravital so the work ~OWW

   cxr first plans are the follow the biological renctione in rabbits with the
two new &rains from the bovine and titih in chickens with the two strains fram the
avian a6 our first adventure.   The reps&t the immunity work with Smaller &iSeS of
organiranrr.

   There iis to be a big meeting in Hew i&ven soon on the BCC). ?Jr Park from the
?Tew York &ard of Wealth is to lead the discussion for the Calmetts ride ,a.nd
Fetroff for the QbBer.  I think that the whole depzrtment will Co up to hear the
discusrsion;  it'ou&ht to be pretty finh

    The new work of Avery La.nd Ceobal just about to come out in the JEM sounds
to me veFJ wonderful.   Don't miss it;  its wonderful chemical work with the sugars.

    Dr. l!Zexner nsked me to write tq? the story of the tantire Y% work from the
begining for the Fall rsport.  ft is for the General 3oard of Mreotors and I havs
put a lot of time on it,   I will send you a cogy if I can get enough oarbone.
Xt was.rather good fun writing it.

    Your friend MrS. R8sor certa&nly puts things through ~?xX!i non 1 sit
awaiti% and &readiw the publicity.  The photogrhphers came !?riday and took
a lot of pictures in the new big laborab$#ry which ze dlbd not get;  they .v8
supposed to have a lot of 10~2 color.  I h=Lven't seen her yet but hov8 had faa
tdks with thw poor wornah who his to write sometMnC: about me.   ft is still a
?eilSrst.   $!r, Vance, the head of the Fictbrial Review, has had a hemorrhage which
soundsto me as if from n gastric ulcer.  3c do not believe that he will get back
to the ,QBffiae a0 soon as they seem to ex-ect.   I fe,lr th?t it ~~a.2 be yite serious.

    I unclarstand that the yellow fever workers are qread over the virus now.
Dr. Mull~r has OUT old room and Mise Tilden who is now on the Staff hal W."xloaU
old office.  k new man, Dr. Irrpin,'w&king with Dr. Vebsb6r has the room the blood
counts were made in,   All of the third floor has been given over to work that
16 dirfjotly uakw m. Z%sners su-oervision and thet I judge was the reason for th.8


extensive moviq this summer.

   3 am awfully sorry not to hl~e you here in the Laboratory:  it was a very
great pleasure to me to have $0~ for two years end I sk\,zll keep on ho?izq thAt th&ngs
may turn out 30 that you will come back to the Instfitute soaa time. At any rate
I shall follow youx work with the gredest pride anO interest.   You knw the real, thing
for r8S~,lrbh.

   The qoans send their veq bast Q-C! nil your friends here inquire often to know
if I have head. from you.  Let us 'knon ezll the interesting things goin& on with you.
Did you know that Besnikoff is to work with Shilling; in Berlin this winter; he
sailed a fen days qo.  The last JAR,& has an zrticle by him to the sffedt that the
S&illirq: differential is of more importVulce thd th rest of the blood count.

V8X7 cordially yours,