2863813	16244771:results of this study showed for the first time that TAFI activity is increased in patients with clonal thrombocytosis
2865094	15836621:Site-directed mutagenesis study validates that cysteine-446 (present in GAD65 as a free sulfhydryl group) plays an important role in GAD65 activity.
2871504	15907840:reporter assay revealed that TNF-alpha-induced TAUT transcriptional activity through the NF-kappaB consensus-like sequence in the human TAUT promoter region
2916729	15778495:proSP-C BRICHOS mutations induce a dynamic toxic gain-of-function, causing apoptotic cell death both by early ER accumulation leading to an exaggerated unfolded protein response and by enhanced deposition of cellular aggregates associated with proteasome
2866585	15879141:Secretion of CAP37, a neutrophil granule protein accumulating on the endothelial cell surface and promoting arrest of monocytes, could contribute to the recruitment of monocytes at inflammatory loci.
3029259	12660734:Defensin 5 transgenic mice were resistant to oral challenge with virulent Salmonella typhimurium; support for a critical in vivo role of epithelial-derived defensins in mammalian host defence
2873509	16116486:specific HRPT2 mutations identified in HPT-JT or sporadic parathyroid carcinoma predicted to truncate parafibromin upstream of or within this NLS disrupt nuclear localization
3029842	15561249:Serum LECT2 levels may be a prognostic indicator of recovery from liver failure.
2863125	12960042:Role for the activin betaC-subunit as a regulatory mechanism to reduce activin A secretion via intracellular heterodimerization.
2863124	11920276:high molecular mass kininogen down-regulates cathepsin G-induced platelet activation by forming a complex with cathepsin G and thus prevents binding of cathepsin G to platelets
2866818	16431947:The CFH Y402H variant is strongly associated with both GA(geographic atrophy) and CNV (choroidal neovascularization) in the U.K. population.
3027640	16024779:JMJD2A selectively represses the expression of the achaete scute-like homologue 2 (ASCL2) gene but not other imprinted genes in the same imprinted locus in HeLa cells
2875701	15504740:the ASIC2a subtype consists of intracellular amino and carboxyl termini and two transmembrane domains connected by a large extracellular loop
2869526	16263090:These findings suggest that the nuclear form of FGF3 inhibits cell proliferation by interfering with ribosomal biogenesis.
2876115	2174051:This paper reports the first purification of a phosphoinositide 3-kinase and shows that the protein is a heterodimer of an 85 kd regulatory subunit that mediates binding to phosphorylated proteins and a 110 kd catalytic subunit.
2871201	15913809:determined the genomic structure of the uroplakin Ia gene and defined the position of a transcriptional start site
3026738	15863492:is part of the peptide-loading complex in the classic route of antigen processing via major histocompatibility complex class I molecules
2875170	16051641:The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness
2872855	16322401:We show overexpression & different splicing of 5-HT4 receptor in aldosterone-producing adenoma tissues in comparison with normal adrenocortical tissue.Isoforms (a) & (b) were not expressed in any APA but were present in majority of normal adrenal cortex.
2870069	16246847:the Arg5-Glu13 salt bridge in alpha-defensin is conserved for defensin in vivo stability
2875072	16081882:Results suggest that the G773D variant of elastin confers structural and functional consequences relevant to the pathogenesis of chronic obstructive pulmonary disease.
3027739	15795266:Brd4 has recently been proposed to mediate the association between bovine papilomavirus1 E2 and mitotic chromosomes.
2864904	15560782:Findings suggest that the basic region of DEC1 participates in the transcriptional regulation through a protein-protein interaction with BMAL1 and DNA binding to the E-box.
3026146	12639247:expression of NFI-B2 impairs CD4 transcription on CDd4-positive primary T-lymphocytes and cell lines in HIV-1 infection
2864966	16283480:KiSS1 is a metastasis suppressor of ovarian cancer and may be a potential molecular target for the treatment
2866376	15378397:proposed a structure of the second gene of 3-gene arrays, Green-pTEX-Green-pTEX-Green-fTEX and Red-pTEX-Red-pTEX-Red-fTEX, in color-vision-deficient subjects
2863408	16144986:Our data strengthen the association between the T8590C polymorphism of CYP4A11 and hypertension and suggest a recessive mode of inheritance.
3026430	16170329:Jasmonates can circumvent drug resistance induced by p53 mutations.
2902877	16285957:Galectin-3 up-regulation of MUC2 transcription occurs at the level of transcription through AP-1 activation in colon cancer cells
2886055	16006654:Results suggest a physiological function of thrombospondin-1 binding to TSG-6 in regulation of hyaluronan metabolism at sites of inflammation.
2875552	16301330:the phosphorylation of APP regulates the formation of a pAPP-JIP-1 complex that accumulates in neurites independent of nonphosphorylated APP
2873258	15165854:interacts with fibrillin-1 and with fibronectin indicating multiple molecular interactions in which this ubiquitously expressed and versatile fibril-associated collagens with interrupted triple helices-collagen can participate
2872252	15778284:Damaged heart may be a target for Reg action, and Reg may protect against acute heart stress.
2868606	15342639:TNIK is a specific effector of Rap2 to regulate actin cytoskeleton
3027230	16148149:HNE causes protein kinase C (PKC) activation and translocation from cytosol to plasma membrane, required for HNE-induced ROS generation and other responses
2873250	12482973:human CGRP-RCP is the genuine orthologue of C17. CGRP-RCP was found to functionally replace C17 in Deltarpc17 yeast cells; CGRP-RCP was identified in a purified human Pol III preparation.
3027132	12972549:Endo180 plays a physiological role in mediating collagen matrix remodelling during tissue development and homeostasis
3024484	16107886:Promoter variation in chitotriosidase is associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia
3024814	16004897:role of MYBPC3 mutations in hypertrophic cardiomyopathy; three new mutations in three families (V771M, V342D, and A627V)were found; findings suggest a dosage effect for mutations at the MYPBC3 gene
2887930	16253141:mRNA level of CYP3A5 is significantly lower in the ascending colon in comparison to the descending and sigmoid colon.
2869014	9722616:This paper deals with AF-6 in mouse, rat, and cow.
3030108	16428483:Elevated glycosylated form of EDN in urine is associated with ovarian cancer
3029682	16044170:Genetic association study revealed the association of single nucleotide polymorphism (SNP)1 (rs10008257) with bipolar disorder.
2870695	12804576:AKAP7gamma is the first nuclear AKAP to bind RI and may be responsible for positioning PKA via RI and/or RII to regulate PKA-mediated gene transcription in both somatic cells and oocytes
2869856	9326641:MIC-1, a divergent TGF-b superfamily cytokine, was cloned from a U937 subtracted cDNA library enriched for activation-associated sequences. It is induced in macrophages by many activation-associated stimuli but not LPS or IFN-g
3028973	15146555:aberrant activation of the Ihh signaling pathway contributes to tumor development in pancreatic cancer
3024670	16155373:SHBG-immunoreactive neurons were observed in the supraoptic nucleus, the suprachiasmatic nucleus, the bed nucleus of the stria terminalis, paraventricular nucleus, arcuate nucleus, the perifornical region and the medial preoptic area in human brains.
2875346	16276415:Mediates downstream signaling mechanisms through G-protein-dependent and -independent mechanisms, which induce cardiac hypertrophy with a distinct phenotype.
2875345	16278592:The expression of TFF3 in chronic graft-versus-host disease of the liver is increased in response to bile duct damage and repair.
2863158	15797629:This suggests that dysregulation of CCND2 and CDK4 plays a specific role in WT tumorigenesis.
2873143	16302974:Data describe the different effects of pH and NaCl on individual O2-binding properties of alpha and beta subunits within liganded tetramer and dimer of human hemoglobin.
3027026	15155714:Thus prolonged exhaustive exercise impaired each of the maximal in vitro Na+-K+-ATPase activity, Ca2+ release, and Ca2+ uptake rates.
3026908	15082783:Results indicate that not only binding to eIF4A but also prevention of eIF4A binding to the MA-3 domain of eIF4Gc contributes to the mechanism by which Pdcd4 inhibits translation.
3027087	16316416:CD56(bright) and CD56(dim) human natural killer-cell subsets exert different functional and cytotoxic activities in response to a live bacterial pathogen.
3028517	16267254:In ischemia/reperfusion models of myocardial infarct, studies with cell types found in vascular tissue, MPO-oxidation products of glycine (formaldehyde) and threonine (acrolein) were the most cytotoxic.
3024215	14707113:CEACAM3 controls human-specific pathogens by the innate immune system.
3026412	15340077:p38delta mitogen-activated protein kinase as a downstream carrier of the PKCdelta-dependent death signal in keratinocytes
2877990	15561101:GALIG encodes a mitochondrial protein promoting cytochrome c release.
2944615	12121677:molecular studies on RCCX haplotypes revealing a unique recombination giving rise to a TNXB/TNXA hybrid gene, CYP21A deletion and CYP21B duplication on one chromosome
2943021	16060676:Binding sites for both protein 4.1R and actin are located in both of the beta I-spectrin calponin homology domains, (CH1 and CH2).
2871135	15576453:These observations strongly suggest the acid-induced current is mediated by ASIC1 channels.
2873330	16424023:data identify rap1GAP as a putative tumor suppressor gene in pancreatic cancer
2872137	11704559:structure and promoter activity, molecular cloning
2870588	16049341:Overexpression of claudin-7 is associated with gastric tumorigenesis
2865938	16244783:A novel RUNX2 missense mutation has been found in members of a family clinically diagnosed with cleidocranial dysplasia.
3027665	16457687:HER-2 overexpression promotes the growth and malignancy of mammary epithelial cells, in part, by conferring resistance to the growth inhibitory effects of TGF-beta
2868641	15768032:beta-catenin displaces Groucho/TLE from Tcf/Lef by binding to a previously unidentified second, low-affinity binding site on lymphoid enhancer factor 1
2875235	15647371:SF3a60, 66, and 120, but not SF1, are essential for pre-mRNA splicing
3027661	11861769:Results show that p63RhoGEF is a RhoA-specific GEF that may play a key role in actin cytoskeleton reorganization in different tissues, especially in heart cellular morphology (p63rhoGEF).
2873683	16288004:Overexpression of sirt1 induced expression of P-glycoprotein and rendered cancer cells resistant to doxorubicin.
3025953	15213259:dysregulation of sdk-1 protein may play an important role in HIV-associated nephropathy pathogenesis
2869053	14560935:The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall.
2876231	16273293:REVIEW: Anti-WNT2B monoclonal antibodies, WNT2B RNAi compounds, or small molecule WNT2B inhibitors could be developed as novel therapeutic agents for gastric cancer and esophageal cancer in the field of clinical oncology.
2981870	15760679:TL1A and DR3 is involved in atherosclerosis via the induction of pro-inflammatory cytokines/chemokines
3005911	15809732:recurrent inactivation of the tumour suppressor RIZ1 suggests that this event may be a significant contributing factor to tumour development in pheochromocytomas and abdominal paragangliomas
2876292	15733269:elastic fiber abnormalities in hypermobility type Ehlers-Danlos syndrome are specific for TNX-haploinsufficient individuals and confirm an important role for TNX in regulating elastic fiber integrity
2864532	15888440:the conformation of NR1 subunit homodimers is affected by the partner NR2 subunits during the formation of heteromeric receptor complexes
2864923	16010966:The involvement of some cationic and aromatic surface exposed residues of eosinophil cationic protein in the inhibition of proliferation of mammalian cell lines was assessed.
2863823	16437728:the 1672T variant of the OCTN1 gene and the -207C variant of the OCTN2 gene represent risk factors for Crohn disease in the Greek population
2877032	15806399:This report describes the first mutations occurring in the coding region of the histidase structural gene in patients with histidinemia.
2871579	16254903:Chromosomes carrying beta(0)39 mutation are characterized by a prevalence of haplotype II (- + + - + + +) (52%) relative to haplotype I (+- - - - + +) (29%).
3025000	11978965:Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome
2863299	15834131:A conserved pattern of alternative splicing in vertebrate MEF2 (myocyte enhancer factor 2) genes generates an acidic activation domain in MEF2 proteins selectively in tissues where MEF2 target genes are highly expressed. (MEF2)
3015569	16335796:Reishi inhibits NOS2 expression in macrophages.
2873282	15961242:Nrg-2-induced Acetylcholine Receptor transcription requires an N-box motif and is regulated by alternative splicing.
2878098	16194898:We present here a case of Follicular Lymphoma with leukemic presentation and a complex translocation involving the IgH, BCL2 and BCL6 loci
2866591	15906358:This genetic cancer vaccineis highly immunogenic and can break tolerance to CEA tumor antigen in CEA transgenic mice.
2863622	15900605:May provide suitable targets for immunotherapy of renal cell carcinoma.
3029751	16416221:TP53 gene mutations alone are not likely to represent a widely useful prognostic marker of the risk of progression to malignancy, at least not in Barrett's esophagus without dysplasia.
3028557	15304323:Centrosomal TACC2 is required for mitotic spindle maintenance.
2943166	9700053:Characterizes the 15-lipoxygenase-1 promoter region and maps the gene to human chromosome 17p13.3.
2874180	16379602:Higher amounts of MIP-1alpha, MIP-1beta, and RANTES were detected in plasma of HIV-1-positive individuals, particularly those with concomitant pulmonary tuberculosis, although the increase was not found to be statistically significant.
2865783	15757827:Deletion pf this geneis a common, and possibly the predominant beta-thalassemia mutation of the Austroasiatic Lao Theung population.
2868983	12039524:TNF-alpha, IL1-beta, and immunoglobulin (GM and KM) gene polymorphisms in sarcoidosis.
2870176	16103878:ADAM23 is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter methylation.
2873471	12628926:This protein is one of 10-12 associated proteins in the purified N-CoR complex.
3027843	16272287:NKp30, among natural cytotoxicity receptors, appeared to be primarily involved in triggering NK cells upon interaction with bone marrow stromal cells
2876181	16286466:Caspases target only Nup93 and Nup96 within the core structure of the nuclear pore complex
2874964	15457851:loss of NECC1 expression is involved in malignant conversion of placental trophoblasts
2890935	16115820:Laforin is a Glycogen-Synthase-Kinase-3 Ser 9 phosphatase, and therefore capable of inactivating GS through GSK3.