BEE-spoke-data/govdocs1-by-extension huggingface dataset:
FXUS66 KSGX 221645
AFDSAN

EXTREME SOUTHWESTERN CALIFORNIA AREA FORECAST DISCUSSION
NATIONAL WEATHER SERVICE SAN DIEGO CALIFORNIA
930 AM PDT MON SEP 22 2003

.SYNOPSIS...HIGH PRESSURE ALOFT WILL CONTINUE THE HOT WEATHER FROM 
THE VALLEYS EASTWARD. A SHALLOW MARINE LAYER WILL KEEP CLOUDS AND 
FOG LINGERING NEAR THE COAST INTO THE AFTERNOON. MOISTURE FROM 
HURRICANE MARTY WILL SPREAD NORTH TONIGHT AND TUESDAY BRINGING 
CLOUDS AND HIGHER HUMIDITIES INTO THE REGION THROUGH WEDNESDAY. 

.DISCUSSION...MARINE LAYER CLOUDS AND DENSE FOG SLOWLY BURNED OFF 
THIS MORNING IN MOST AREAS BUT A STRONG INVERSION WILL LIKELY KEEP 
CLOUDS LINGERING AT SOME BEACHES THROUGH THE AFTERNOON. FARTHER 
INLAND IT WILL BE HOT ONCE AGAIN WITH THE UPPER RIDGE PARKED OVER 
THE SOUTHWEST WITH HIGHS ONCE AGAIN ABOVE 100 IN THE INLAND VALLEYS 
AND FOOTHILLS. 

ATTENTION TURNS SOUTH TOWARD HURRICANE MARTY OVER THE SOUTHERN BAJA 
PENINSULA. THE NGM AND MESOETA ARE BULLISH ON BRINGING ITS MOISTURE 
NORTHWARD INTO SOCAL WEDNESDAY...WHICH IS VASTLY DIFFERENT FROM THE 
MORE BEARISH (AND PREFERRED) AVN SOLUTION WHICH KEEPS THE DEEP 
MOISTURE JUST SOUTH OF THE BORDER. TEMPERATURE FORECASTS WILL BE 
TRICKY AS THE EASTERLY FLOW COULD DISRUPT THE MARINE LAYER RESULTING 
IN WARMER WEATHER REACHING ALL THE WAY TO THE COAST. IT WILL 
ALSO BECOME INCREASINGLY MORE HUMID MIDWEEK AS SUBTROPICAL MOISTURE 
SURGES NORTHWARD. 

ZONES WERE UPDATED TO REMOVE DENSE FOG ADVISORY FROM THE COASTAL 
AREAS. 

SAN...NONE.

$$

MOEDE
Accelerator Physics Video Conference Minutes, 6/20/2000


Participants:

BNL:	N. Catalan-Lasheras, A. Fedotov, Y.Y. Lee, N. Malitsky, D. Raparia, B. Weng
JLAB:	G. Kraft
LANL:	N. Bultman, D. Gurd, A. Regan, R. Schafer, J. Stovall
LBNL:	R. Keller, J. Staples
ORNL:	S. Danilov, G. Dodson, J. Galambos, J. Holmes, D. Jeon, S. Kim, J. Wei, 
	M. White, K. Woody


1a) 2nd Target Layout Decision

D. Raparia discussed  RTBT redesign to incorporate the 2nd target station.  To provide 
additional protection to workers in the target station area, it is proposed to move a 
3 meter block of iron into the RTBT.  Due to the attenuation factor of the iron, it is 
estimated that incident bunches of 10^14 protons would result in only 0.2 mRad after 
the iron. 


1b) H-minus Stripping in the RF Linac

Deepak reported that it would require an E field of 162 MV/m to cause H-minus stripping
at the level of the 0.3 T dipole in the injection chicane.  Thus, H-minus stripping in 
the linac due to E fields should not be a problem.


2) Mini-ASAC Comments and Report

The response of the ASAC committee to the 1 klystron/cavity architecture was very 
positive.  They find this much more robust than the previous use of multiple cavities/
klystron and fast phase shifters.  They see no identifiable risks in the present design.
The only suggestion for cutting cost was to buy the waveguides more cheaply in Germany.

Concerns include the 4 meter drift between the warm and cold linac sections, which was 
not included in the simulations.  The end-to-end beam dynamics, which starts with a 
waterbag distribution at present, will be repeated using simulated RFQ output distributions 
obtained by John Staples.  The 550 kW klystron power rating is marginal, and may be too 
weak to get full performance from the good cavities.

The present linac design results in an overall cost increase of between $8M and $15M when
compared to the March baseline.  It may be possible to obtain some decrease in this figure
from conventional facilities through reduced air conditioning requirements.


3) RF Instrumentation Requirements for the RFQ and Associated Waveguide

This will be coordinated between LANL and LBNL.


4) EPAC Meeting

SNS Papers: BNL ~25, JLAB 0, LANL 2, LBNL 2, ORNL 4
See EPAC Proceedings for details.


5) Miscellaneous

LANL and LBNL discussed the use of steering windings in the MEBT for carrying out a DTL
acceptance scan.  Present range of MEBT steering windings gives +/- 5 mR.  The design of 
these windings, as well as of the main quadrupole windings and iron cores, has been completed, 
and the parts are being constructed.  Methods of achieving greater deflections are being 
discussed.

A global coordinate system for the SNS drawings to be used for construction was discussed. 
It was agreed that the system should place SNS in the region of positive coordinate values, 
be of a right-handed orientation, and use metric units.


6) Next Video Conference

The next video conference will be on Tuesday, 7/11/2000.
MD5 cryptographic checksums created: Wed Oct 22 19:50:34 2003
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For directory: /nodc/archive/arc0001/6300127/01-version
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"Lexington march [and] Roland march","sm/sm1884/09300","09345","010.gif","10","10","","010.tif"
"Lexington march [and] Roland march","sm/sm1884/09300","09345","011.gif","11","11","","011.tif"
"Lexington march [and] Roland march","sm/sm1884/09300","09345","012.gif","12","12","","012.tif"
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"Lexington march [and] Roland march","sm/sm1884/09300","09345","024.gif","24","24","","024.tif"
292 
est moins sr d'avoir les rieurs de son ct. Mais, quel
sujet pour la satire ! La religion, institue pour le salut
ternel des hommes, pour les corriger et pour les consoler,
la religion, qui enseigne l'galit et la fraternit, cette
religion devient le prtexte d'actes qui outragent tous les
principes qu'elle proclame ! Et l'on peut dire que la
satire de Montesquieu est  la hauteur du sujet. On ne
peut imaginer une phrase plus accablante que celle-ci :
< Ces brigands, qui voulaient absolument tre brigands et
chrtiens, taient trs dvots.  Or, on peut voir qu'au
moment o Montesquieu crivait, le souci de la religion
figurait en tte du Code Noir (1).
Tout le monde s'accorde  considrer le chapitre 5
comme un chef-d'uvre satirique et comme le plus cla-
tant tmoignage de l'humanit de Montesquieu. Ces phra-
ses, courtes et nergiques, font plus de besogne que des
volumes. Montesquieu veut runir dans ce chapitre les
fausses doctrines conomiques et les prjugs de l'orgueil
europen pour en montrer la sottise et la cruaut.
Or, au lieu de dclamer contre l'esclavage, il choisit
la forme plus efficace de l'ironie. Pour finir de montrer
comment l'esclavage ne peut avoir de base dans la raison,
il allgue une srie de raisons absurdes en sa faveur. Mais
tout absurdes qu'elles soient, ces raisons sont celles qui
servaient alors  justifier l'esclavage.
Ce sont sans doute des arguments courants de gens du
monde, des arguments qui devaient persister encore cent
ans en France avant d'tre dfinitivement vaincus.
L'autorit tait toujours proccupe de la ncessit de
faire valoir les terres et le commerce des colonies. Les
colons, de leur ct, affirmaient que les esclaves taient
absolument indispensables. Quel spectacle pour le mora-
liste que celui des peuples d'Europe qui ont dj exter-
min des nations et qui sont en train d'en dtruire d'au-
tres ! Au lieu de se repentir de leurs crimes, les Europens
y ajoutent d'autres, encore plus atroces.
Et il faut absolument des esclaves pour assurer la fabri-
(1 V. le Code de la Louisiane, Savary Desbruslons, Dictionnaire de
Commerce, t. II, col. 73 et suiv.
TITLE
U. V. Monitoring Program at U. S. EPA

AUTHOR(S)
Barnard, W. F., and Cupitt, L. T.

PERFORMING ORGANIZATION NAME AND ADDRESS
Atmospheric Research and Exposure Assessment
Laboratory
U. S. Environmental Protection Agency
Research Triangle Park, NC

SPONSORING AGENCY NAME AND ADDRESS

Atmospheric Research and Exposure Assessment
Laboratory
U. S. Environmental Protection Agency
Research Triangle Park, NC

ABSTRACT
     The U. S. Environmental Protection Agency (EPA) has initiated
a program to develop and operate a monitoring network to measure
ultraviolet (UV) radiation flux at the earth's surface and to
provide for public awareness of exposure to UV radiation through
adaptation and publication of a predictive UV "exposure Index." 
This "Index," similar to the one developed and publicized by Canada
in 1992, is being developed in conjunction with the National
Weather Service for possible public distribution this year. 
Current plans call for a 15 site monitoring network to measure UV
intensities on a spectrally-resolved basis, together with other
parameters (e.g., total column ozone, cloud cover, interfering
tropospheric pollutants, etc.) that affect UV flux.  Eleven urban
sites will provide data to validate the "Index" predictions in
proximity to ~25% of the U.S. population.  The combination of urban
(polluted) and four rural (less polluted) sites will enable EPA to
improve the algorithms upon which the "index" predictions are
based.  A series of instrumental intercomparisons with other
agencies are also planned to ensure comparability of data and good
quality assurance/quality control.  EPA's intent is to coordinate
its efforts with other Federal Agencies and with the international
community.
(   i8o )
limites d'une sage libert; dtromper les cam-
pagnes fanatises ; utiliser les   ressources que
le pays prsentait;  intimider les ennemis de
l'indpendance du peuple; faire fleurir l'agri-
culture et les arts ; rouvrir les universits ; prter
son appui  la religion; interdire l'arme perfide
du stylet ; proscrire les assassins ; empcher les
exactions, et touffer jusqu'aux derniers fermens
de discorde ; telles tgient les obligations, que
Grouchy s'tait imposes en acceptant le gou-
vernement militaire d'un territoire que la France
devait, protger. En vain quelques insurrections
clatrent-elles dans les provinces d'Acqui et du
Mont-Ferrat. Les rebelles furent compltement
dfaits; plus de six cents prirent ; le reste fut
dispers. Acqui tomba de nouveau au pouvoir
des Franais. Strvi, l'un des foyers de la rebel-
lion , o un dtachement de la vingt-neuvime
demi-brigade avait t tratreusement  assailli,
fut livr aux flammes : exemple terrible, mais
ncessaire  la sret de l'arme.
Pendant la campagne de 1799, en Italie,
Grouchy se trouva sous les ordres de Moreau,
avec qui il se lia d'une troite amiti. Tantt
 la tte d'une division, tantt comme chef de
Ftat-major , il prit part  tous les combats de
cette campagne difficile et glorieuse. Il dploya
REDOUBT VOLCANO
Date	SO2 rate	n	s.d.	CO2 rate
20-Mar-90	4609	5	534	n.m.
21-Mar-90	2033	8	261	n.m.
22-Mar-90	1609	6	148	n.m.
23-Mar-90	2502	6	97	n.m.
24-Mar-90	3798	4	182	n.m.
01-Apr-90	3892	9	1151	n.m.
06-Apr-90	3662	6	619	n.m.
07-Apr-90	2819	7	584	n.m.
08-Apr-90	4145	8	433	n.m.
11-Apr-90	4826	7	1381	n.m.
11-Apr-90	2510	8	190	n.m.
14-Apr-90	1691	8	286	n.m.
17-Apr-90	5855	8	752	n.m.
22-Apr-90	3464	8	584	n.m.
25-Apr-90	6121	8	967	n.m.
27-Apr-90	3601	8	939	n.m.
03-May-90	3258	6	540	n.m.
04-May-90	4115	9	323	n.m.
19-May-90	3116	9	402	n.m.
20-May-90	4177	9	534	n.m.
22-May-90	4150	10	894	n.m.
25-May-90	2492	11	404	n.m.
01-June-90	1249	6	99	n.m.
02-June-90	1489	4	421	1200
05-June-90	3814	4	261	2400
07-June-90	1601	7	313	n.m.
09-June-90	2340	6	198	n.m.
11-June-90	2462	3	39	n.m.
30-June-90	657	6	100	n.m.
04-July-90	868	6	174	n.m.
12-July-90	1591	9	132	n.m.
16-July-90	1131	6	205	n.m.
19-July-90	2179	6	121	n.m.
03-Aug-90	1660	6	219	n.m.
13-Aug-90	1008	5	115	n.m.
14-Aug-90	2376	6	138	n.m.
15-Aug-90	1002	6	183	n.m.
15-Aug-90	742	6	37	n.m.
15-Aug-90	2609	5	368	n.m.
31-Aug-90	469	5	161	n.m.
07-Sept-90	188	4	21	n.m.
07-Sept-90	680	3	81	n.m.
13-Sept-90	723	4	78	n.m.
25-Sept-90	297	6	43	n.m.
28-Sept-90	897	6	89	n.m.
03-Oct-90	366	8	21	n.m.
15-Oct-90	586	4	36	n.m.
21-Oct-90	510	9	76	n.m.
27-Oct-90	162	8	36	n.m.
08-Nov-90	577	8	158	n.m.
23-Jan-91	297	2	140	n.m.
21-Mar-91	35	7	10	n.m.
04-Apr-91	149	9	45	n.m.
10-Apr-91	29	5	11	n.m.
06-May-91	73	5	25	n.m.
22-May-91	24	4	7	n.m.
31-May-91	0	2	0	n.m.
21-Aug-91	0	2	0	n.m.
14-May-92	0	1	0	n.m.
14-Oct-92	0	2	0	0
23-Oct-92	0	1	0	0
15-Nov-92	0	1	0	0
24-Apr-93	0	2	0	0
07-July-94	0	2	0	0
SPURR VOLCANO
Date	SO2 rate	n	s.d.	CO2 rate
22-Jul-91	0	1	0	n.m.
21-Aug-91	0	2	0	n.m.
29-Aug-91	0	2	0	n.m.
03-Sep-91	85	2	18	n.m.
22-Nov-91	0	2	0	n.m.
14-May-92	88	2	10	n.m.
08-Jun-92	21	2	4	n.m.
29-Jun-92	5	5	3	n.m.
10-Sep-92	0	0	0	n.m.
21-Sep-92	23	5	12	n.m.
23-Sep-92	24	4	7	n.m.
24-Sep-92	79	3	11	n.m.
25-Sep-92	300	4	54	11000
28-Sep-92	194	4	25	12000
29-Sep-92	749	3	75	8700
02-Oct-92	452	2	0	n.m
03-Oct-92	220	4	114	4800
04-Oct-92	212	4	72	3500
05-Oct-92	356	4	173	2900
10-Oct-92	243	3	100	n.m
14-Oct-92	47	3	4	2400
15-Oct-92	64	2	4	n.m.
16-Oct-92	105	4	16	>2000
19-Oct-92	0	1	0	>0
23-Oct-92	24	2	3	2100
29-Oct-92	0	1	0	>0
10-Nov-92	0	1	0	0
11-Nov-92	0	3	0	0
12-Nov-92	0	1	0	1100
13-Nov-92	0	1	0	1000
15-Nov-92	0	1	0	1000
08-Dec-92	0	1	0	>1000
11-Dec-92	0	1	0	>500
15-Dec-92	0	1	0	3200
18-Dec-92	0	1	0	>1000
23-Dec-92	0	1	0	>1000
21-Jan-93	0	1	0	>1000
18-Feb-93	0	1	0	>400
24-Apr-93	0	1	0	>930
07-Jul-94	0	1	0	0
ILIAMNA VOLCANO
Date	SO2 rate	n	s.d.	CO2 rate
20-Mar-90	0	2	0	n.m.
05-June-90	0	2	0	n.m.
31-May-91	24	4	5	n.m.
13-June-91	18	2	4	n.m.
21-Aug-91	41	3	9	n.m.
21-Nov-91	0	3	0	n.m.
23-Oct-92	35	2	6	0
24-Apr-93	38	2	5	0
07-July-94	19	2	6	0
AUGUSTINE VOLCANO
Date	SO2 rate	n	s.d.	CO2 rate
20-Mar-90	0	2	0	n.m.
13-June-91	4	3	1	n.m.
21-Aug-91	0	2	0	n.m.
20-Nov-91	0	2	0	n.m.
14-May-92	0	2	0	n.m.
23-Oct-92	0	1	0	0
07-July-94	0	2	0	0
Feb. 03, 2009

Ruth Dasso Marlaire 
Ames Research Center, Moffett Field, Calif. 
650.604.4709
ruth.marlaire@nasa.gov 

RELEASE: NASA Scientists

NASA SCIENTISTS DISPROVE 'LOST GENE' THEORY IN WOOD-EATING FUNGI

In Yellowstone National Park, east of the Virginia Cascade cutoff, 
NASA scientists found a site composed solely of pine trees and, for 
the next two years, proceeded to gently twist off one half of the 
pine needles at the base. By artificially defoliating the trees, the 
scientists wanted to examine the wood-degrading capability of a 
fungus that has the potential to digest toxins found in the soil. 

Scientists are working to isolate the gene that causes Ectomycorrhizal 
(EM) fungi to digest wood and its toxins, such as phenolics, which 
are contaminants similar to those found in soil and groundwater. 

A study led by Ken Cullings and Galina Ishkhanova of NASA Ames 
Research Center, Moffett Field, Calif. and Joan Henson of Montana 
State University, Bozeman, Mont. found evidence that the gene in the 
dominant EM fungal species (Suillus granulatus) produced 
wood-degrading enzymes, and that enzymatic activity increased 
significantly during defoliation. The study appeared in the July 2008 
issue of Oceologia. 

For a long time, scientists knew that a group of EM fungi was related 
to a wood-rotting fungus. Over time, EM fungi evolved into organisms 
that are dependent on their host plants for food, and no longer use 
their capability to break down wood for food. Scientists suspected 
that these fungi may have lost the genes necessary to convert wood 
into food. 

However, they found that was not the case. 

"Our study showed that not only do mycorrhizal fungi still have the 
gene, but the gene can be highly stimulated by removing some of the 
needles from the host tree, which restricts photosynthesis and the 
production of sugar at its root. It disproves the 'lost gene' 
theory," said Cullings. 

Scientists now believe that EM fungi have the potential to play a 
significant role in carbon, nitrogen and phosphate cycling in the 
Earth's forested ecosystem. They also found many above-ground factors 
that reduce photosynthetic potential, or divert fixed carbon from 
roots, and may have wide-reaching effects on the ecosystem. 

"I'm working to clone out the mycorrhizal toxin-degrading genes to get 
a purified enzyme of high activity use. For instance, it can be used 
as a toxic spill clean-up strategy," said Cullings. 

Related studies include comparing the effect of lost needles to plant 
diseases, such as dwarf mistletoes and pine beetles, which are 
killing record numbers of pines in the west. Scientists think that 
these diseases are increasing in range and scope due to global 
climate change, and that the break down of wood also releases carbon 
dioxide. Currently, Cullings is undertaking experiments that will 
allow these phenomena to be added to global climate change models for 
the first time. 

For more information about NASA and agency programs on the Internet, 
visit: 

http://www.nasa.gov/home/index.html

	
-end-
( -26)
Ions, chacun de io compagnies; chaque compagnie
tai^compose de 3 officiers et de 80 sous-officiers et
soldats. On affecta,  chaque bataillon, deux pices
de canon  la Rostaing, servies par 8 fusiliers, jouis-
sant d'un sol de haute-paie (1).
Outre ces rgimens coloniaux, on jugea bientt
ncessaire de faire passer d'autres troupes aux An-
tilles. Le rgiment d'Armagnac fut envoy  la Gua-
deloupe*, son 2* bataillon y dbarqua le 22 novem-
bre 1775; le 1" bataillon n'y arriva que le 3o
novembre 1777.
Pendant la guerre de l'indpendance des Etats-
Unis, le rgiment d'Auxerrois y fut galement, en-
voy. A la paix de 1783, il en repartit, le 24 mars,
avec celui d'Armagnac, pour revenir en France.
Le 26 fvrier 1784, une ordonnance du roi pres-
crivit l'incorporation de diverses troupes, employes
au dpartement des colonies, pour former un 3'
bataillon aux rgimens de la Martinique et de la
Guadeloupe, parce que, depuis la paix, ces deux
rgimens fournissaient,  Sainte-Lucie et  Tabago,
chacun un bataillon, qu'on ne relevait que tous les
ans, et qui perdait considrablement d'hommes,
surtout celui de Sainte-Lucie, par la grande insa-
lubrit de cette le.
(i) Ordonnance du roi, du 1er mai 1775.
\\ Species Tag:        &   49001 & Name:&  O3-sym-O-17    
\\ Version:            &       2 & & Ozone,
\\ Date:       &  Mar. 1995      & & symmetric $^{17}$O isotope
\\ Contributor:&  E. A. Cohen    & & 
\\             &                 & & 
\\ Lines Listed:       &   26092 & Q(300.0)=&    20803.525 
\\ Freq. (GHz) $<$     &    4603 & Q(225.0)=&    13507.522 
\\ Max. J:             &      76 & Q(150.0)=&     7352.785 
\\ LOGSTR0=            &    -8.5 & Q(75.00)=&     2605.615 
\\ LOGSTR1=            &    -8.0 & Q(37.50)=&      928.081 
\\ Isotope Corr.:      &  -3.432 & Q(18.75)=&      334.464 
\\ Egy. (cm$^{-1}$) $>$&     0.0 & Q(9.375)=&      123.884 
\\ $\mu_a$ = &                   & A=& 102351.
\\ $\mu_b$ = & 0.5337            & B=&  13350.8
\\ $\mu_c$ = &                   & C=&  11781.7
\headend 

	The spectra are from E. A. Cohen, K. W. Hillig II, and H. M. Pickett,
1995, J. Mol.\ Struct.\ {\bf 352/353,} 273. The calculation fixes centrifugal
distortion constants beyond the sextic terms to those of the parent species
with the exception of the coefficients of $P_a^{2n}$ which are assumed to
be proportional to $A^n$.  The dipole moment was assumed to be the same as for
the parent species, however centrifugal corrections have not been applied. 
Where several experimental lines have the same frequency,
the uncertainties refer to the center of a blended feature, not to the
individual components.
FRENCH OCCUPATION.                       663
mouth and up the Mississippi to its sources, appears to me, to be the boundary between the French and us in that part of the Country, and of course become our Frontiers; as the west side of the Mississippi will no doubt be settled by the French, I would offer to your Lordw consideration, whether it would not be good policy at this time while we certainly have it in our power to secure all the advantages we have got there by making a purchase of the Indians inhabiting the Country along the Mississippi from the mouth of the Ohio up to the sources of the River Illinois, and there plant a respectable colony, in order to secure our frontiers, and prevent the French from any attempt to Rival us in the Fur trade with the Natives, by drawing the Ohio and Lake Indians over the Mississippi, which they have already attempted by the last accounts we have from Detroit. From planting this new Colony, many great advantages would arise to this Kingdom as well as to His Majesty's subjects in North America; it would extend Trade and commerce with the furthermost Nations of western Indians hitherto unknown to us, which would enable the Trading people in the Colonies, to import more of the Manufactories of this Kingdom, than they have, heretofore done, which is an object of the greatest consequence to a Trading people; it would extend His Majesty's settlements in America, and make his subjects appear more formidable in the Eyes of the Indians, which is now become absolutely necessary, in order to preserve the peace between them and us; it would cut off all connections between the French and those Nations settled over that large Tract of Country on this side of the Mississippi and give us the absolute dominions over all the upper Lakes: Huron, Michigan and Superior, and bid fair for giving an everlasting peace to His Majly" Southern Colonies; besides, from this Colony in a very few years, we should be able to supply with provisions of every kind the several posts or marts, that may be erected for Trade with the Natives on much easier terms than they have or can be supplied from any of our Colonies. At present it may be objected, that the establishing such a Colony, so far from the sea, will be attended with too great an expence to the Nation, which may be easily answered. The fertility of the Country and the fineness of the Climate is now known to us, which is sufficient to encourage industrious people to settle it, in a very little time without any expence to the Nation or hindrance to the growth of the present Colonies, and I dare say, people enough will be found that will undertake it.
Your Lordpp" may be surprised that after the conquest of all Canada, and as soon, as a paee took place between England & France, and the Natives convinced that His Majesty's Anns
From: Koonin, Eugene (NIH/NLM/NCBI)
Sent: Monday, August 22, 2005 8:21 PM
To: NLM/NCBI List ncbi-seminar
Cc: 'Cheol-Min Ghim'
Subject: Seminar September 1

Thursday, September 1, 11 AM

Bldg. 38A, B2 conference room

Cheol-Min Ghim 

Center for Theoretical Biological Physics University of California, 
San Diego

Lethality and synthetic lethality in the genome-wide metabolic network of
Escherichia coli
****************************************************************************
Recent genomic analyses on the cellular metabolic network show that reaction
flux across enzymes are diverse and exhibit power-law behavior in its
distribution. While intuition might suggest that the reactions with larger
fluxes are more likely to be lethal under the blockade of its catalysing
gene products or gene knockouts, we find, by in silico flux analysis, that
the lethality rarely has correlations with the flux level owing to the
widespread backup pathways innate in the genome-wide metabolism of
Escherichia coli. Lethal reactions, of which the deletion generates
cascading failure of following reactions up to the biomass reaction, are
identified in terms of the Boolean network scheme as well as the flux
balance analysis. The avalanche size of a reaction, defined as the number of
subsequently blocked reactions after its removal, turns out to be a useful
measure of lethality. As a means to elucidate phenotypic robustness to a
single deletion, we investigate synthetic lethality in reaction level, where
simultaneous deletion of a pair of nonlethal reactions leads to the failure
of the biomass reaction. Synthetic lethals identified via flux balance and
Boolean scheme are consistently shown to act in parallel pathways, working
in such a way that the backup machinery is compromised.

Eugene V. Koonin, PhD, Senior Investigator
National Center for Biotechnology Information
National Library of Medicine
National Institutes of Health
Bethesda, MD 20894
Telephone 301-435-5913
Fax 301-435-7794
000
WWUS54 KOUN 100239
SVSOUN

SEVERE WEATHER STATEMENT
NATIONAL WEATHER SERVICE NORMAN OK
937 PM CDT WED APR 9 2008

OKC005-100300-
/O.CON.KOUN.SV.W.0261.000000T0000Z-080410T0300Z/
ATOKA OK-
937 PM CDT WED APR 9 2008

...A SEVERE THUNDERSTORM WARNING REMAINS IN EFFECT UNTIL 1000 PM CDT
FOR NORTHEASTERN ATOKA COUNTY...

AT 937 PM CDT...NATIONAL WEATHER SERVICE DOPPLER RADAR DETECTED 
SEVERE THUNDERSTORMS BETWEEN REDDEN AND STRINGTOWN...MOVING 
NORTHEAST AT 30 MPH. DIME TO QUARTER SIZE HAIL AND 60 MPH WINDS ARE 
LIKELY.

* LOCATIONS IN THE WARNING INCLUDE ATOKA RESERVOIR...CHOCKIE...
  DAISY...NORTHWESTERN MCGEE CREEK LAKE...REDDEN AND STRINGTOWN.

SEVERE THUNDERSTORMS CAN PRODUCE TORNADOES WITH NO ADVANCE WARNING.
MOVE IMMEDIATELY TO A STORM SHELTER... BASEMENT OR STURDY BUILDING IF
A TORNADO IS SIGHTED.

LAT...LON 3458 9565 3428 9607 3431 9615 3468 9602
      3464 9587 3460 9585 3461 9584 3461 9577
TIME...MOT...LOC 0237Z 215DEG 30KT 3451 9586

$$

JAMES
*This is an archive page. The links are no longer being updated. 
1991.11.05 :  Secretary's Distinguished Public Service Award -- Suzanne Somers

Contact:  HHS Press Office (202) 245-6343
November 5, 1991

       HHS Secretary Louis W. Sullivan, M.D., today presented
actress/author Suzanne Somers with the Secretary's Award for
Distinguished Public Service for her efforts to educate the
public about the impact of alcoholism on families.
       "Because of the efforts of Suzanne Somers, millions of
Americans who suffered through similar childhood trauma have
found a measure of relief in knowing that they were not alone,"
Sullivan said in presenting the award.  "Suzanne Somers has
demonstrated outstanding leadership and personal courage in her
work with family alcoholism."
       Secretary Sullivan also presented a Distinguished Public
Service Award to ABC Entertainment for its community service in
airing "Keeping Secrets," a made-for-television movie of Somers'
life as the child of an alcoholic, and for developing and
distributing a viewing guide.  John Sias, president of ABC
Television Network Group, accepted the award on behalf of the
network.
       A public service announcement aired immediately following
the movie featured the HHS National Clearinghouse for Alcohol and
Drug Information 800 number.  Members of the National Coalition
for Children of Alcoholics Education contributed materials and
listed their helpline numbers in the resource materials.
       "Many of the more than 2,000 callers said they had never
told anyone about their family's alcohol problems,"  Sullivan
said.  "And, many asked the volunteers answering the phones to
tell Ms. Somers that her courage had inspired them to reach out
for help."
       Seventy-six million Americans -- about 43 percent of the
U.S. adult population -- have been exposed to alcoholism in the
family.  Almost one in five Americans (18 percent) lived with an
alcoholic growing up.
       The Department of Health and Human Services, through the
Office for Substance Abuse Prevention:
     o    Provides demonstration grants targeted to children of
          alcoholics;
     o    Works in conjunction with the Department of Education
          to reach 5th through 8th graders who live with
          alcoholism through the "Positive Connections for Kids"
          program;
     o    Conducts a public service campaign, "Alcoholism Tends
          to Run in Families...;"
     o    Sponsors technical conferences to bring researchers and
          clinicians together for enhanced communication and
          cooperation;
     o    And, operates the Information Clearinghouse and RADAR
          Network.
     The National Clearinghouse for Alcohol and Drug Information
can be reached at 1-800-729-6686.

                              ###
4/17/05

Re-run steps using corrected hetgrmfs.perl,
hetgarfs_ciao321.pro, and mkhetgarcspec.pro

1. For each sequence go into the analysis directory
and delete some files:

rm -fr *o1.rmf*
rm -fr *fitspec.tar*
rm -fr *asciispec.tar*
rm -fr *garf.fits*
rm -fr fits_spectra/*
rm -fr ascii_spectra/*

2. Re-do everything starting from step [A],
part (5) in the regular instructions (i.e.
pick up from the point where you run hetgrmfs.perl).

The only change you have to make in re-running the
ARF files part is that you do

IDL>hetgarfs_ciao321,rootname,/cdir,/auxdir

(the previous instructions did not have the /auxdir part).

HOWEVER, when you do the reprocessing for a completely
new sequence you must omit the /auxdir.

3. Re-do steps [B] and [D] exactly as before.
(you don't have to re-do step [C]).
*This is an archive page. The links are no longer being updated.

1992.05.29 :  Medicare Home Health Agencies

Contact: Bob Hardy (202) 245-6145
May 29, 1992
       
HHS Secretary Louis W. Sullivan, M.D., announced today that
home health agencies approved by the Community Health Accreditation
Program will be recognized as meeting the requirements for
participation in the Medicare program.
       This recognition, known as "deemed status," will allow home
care organizations accredited by CHAP the opportunity to
participate in the Medicare program. Of the nearly 6,000 home
health agencies that serve Medicare beneficiaries, CHAP has
accredited 250 agencies and branches.
       "CHAP's standards meet the requirements of the Medicare
program to assure a high quality of care for beneficiaries,"  said
Dr. Sullivan.
       To participate in the Medicare program, providers of health
care services must initially be certified by a state survey agency
as complying with federal law. State authorities then conduct
periodic surveys to determine compliance with Medicare standards,
except when the approval of an accrediting organization is
recognized by law as assuring compliance.
       The recognition of CHAP accreditation for home health
agencies means they will not be subject to the routine inspections
by state survey agencies.

                             - More -

                               - 2 -

        William Toby Jr., acting administrator of the federal
Health Care Financing Administration, said that CHAP "must release
reports of its surveys of home health agencies to HCFA on a routine
basis and release reports to the public upon request. 
       "If the CHAP survey reports reveal deficiencies, HCFA may
survey the identified provider and require corrective measures or
withdraw deemed status," Toby said.
       HCFA will perform announced and unannounced validation and
complaint surveys to assure Medicare conditions are maintained.  
       Before CHAP was approved as the accrediting organization,
its standards were compared to relevant Medicare requirements. 
After reviewing CHAP's accreditation program, HCFA determined that
Medicare conditions and survey requirements were met by CHAP.
Recognition of CHAP accreditation is complete with publication of
a notice in today's Federal Register.
       CHAP-accredited home health agencies will be granted deemed
status beginning 90 days after publication of the final notice in
the Federal Register. 

                                ###
<chem>
<exampleName>Chemical equilibrium problem</exampleName>
<category>MULTI</category>
<solver>GAMS-AMPL</solver>
<inputMethod>GAMS</inputMethod>
<comment>
Chemical equilibrium problem with 5 equations, 12 variables,
and 37 non-zeroes.
</comment>

<opt>
option solver loqo;
</opt>

<model><![CDATA[
$TITLE CHEMICAL EQUILIBRIUM PROBLEM  (CHEM,SEQ=21)
*  THE PROBLEM IS TO FIND THE EQUILIBRIUM COMPOSITION OF A
*  MIXTURE OF DIFFERENT ATOMS.
*
*  REFERENCE: BRACKEN J AND MC CORMICK I P, SELECTED APPLICATIONS OF
*            NONLINEAR PROGRAMMING, JOHN WILEY AND SONS, NEW YORK, 1968.
*            (CHAPTER 5)

 SETS  C  COMPOUNDS / H, H2, H2O, N, N2, NH, "NO", O, O2, OH /
       I  ATOMS     / H  HYDROGEN, N  NITROGEN, O  OXYGEN /

        TABLE  A(I,C)  ATOMS PER COMPOUND

      H  H2  H2O  N  N2  NH "NO" O  O2  OH
 H    1   2    2          1              1
 N                1   2   2   2
 O             1              1  1   2   1

 PARAMETERS MIX(I)   NUMBER OF ELEMENTS IN MIXTURE / H=2, N=1, O=1 /
            GIBBS(C) GIBBS FREE ENERGY AT 3500 K AND 750 PSI /
            H  -10.021,  H2  -21.096,  H2O -37.986,  N   -9.846, N2 -28.653
            NH -18.918, "NO" -28.032,  O  -14.640,   O2 -30.594, OH -26.11 /
            GPLUS(C) GIBBS ENERGY PLUS PREASSURE ;

  GPLUS(C) = GIBBS(C) + LOG(750*.07031); DISPLAY GPLUS;

 VARIABLES X(C)    NUMBER OF MOLS IN MIXTURE
           XB      TOTAL NUMBER OF MOLS IN MIXTURE
           ENERGY  TOTAL FREE ENERGY IN MIXTURE
 POSITIVE VARIABLES X, XB;

 EQUATIONS CDEF(I) COMPONENT DEFINITION
           EDEF    ENERGY DEFINITION
           XDEF    TOTAL MOL DEFINITION ;

 CDEF(I)..  SUM(C, A(I,C)*X(C)) =E= MIX(I);

 XDEF..     XB =E= SUM(C, X(C));

 EDEF..     ENERGY =E= SUM(C, X(C)*(GPLUS(C) + LOG(X(C)/XB)));

 X.LO(C) = .001; XB.LO = .01;

 MODEL MIXER CHEMICAL MIX FOR N2H4+O2 / ALL /;

 SOLVE MIXER MINIMIZING ENERGY USING NLP;

]]></model>
</chem>
Subject: Reference File No. S7-24-99
Author:  "Lisa" <lisau@libertybay.com> at Internet 
Date:    12/05/1999 2:38 PM
     
     
Reference File No. S7-24-99
     
December 5, 1999
     
I write this email in support of the adoption of regulations on short sales of 
stocks outside of the NASDAQ market. The prices of OTC:BB stocks have been 
greatly manipulated and good companies are being held down by such manipulation.
Without regulations put in place, the average investor's chances of realizing 
any profits by investing in smaller companies not yet on the NASDAQ are greatly 
diminished These investors are losing money on good companies with the potential
for great futures every day. Not only are the investors greatly hurt, so are 
many promising companies.
     
I believe the biggest threat to the OTC:BB market is the illegal shorting 
(selling non-existent shares) that goes on by market makers and foreign 
brokerage firms. This practice is fraudulent and should not be allowed to go on 
in the OTC:BB market. When market makers can sell unlimited non-existent shares,
how can true market value ever be established. I believe the SEC should take a 
serious stand on this issue and start protecting the public from such blatant 
acts. The SEC should regulate short sales in these markets as they do for listed
stocks. 
     
This corruption needs to be stopped. We need to protect the rights of the 
individual investor, so I strongly feel the SEC should pass these necessary 
regulations. 
     
Sincerely, 
     
Lisa Ulshafer
ID#                : P00262IBMPC00
					RSIC#              : PSR-262 MICRO
					CODE PKG NAME      : CASKCODES
					COMPUTER           : IBM PC,
							     IBM PC/XT,
							     IBM PC/AT
					PACKAGED           : 03/30/88

************************************************************************
DESCRIPTION                                             NUMBER OF BYTES
************************************************************************

1.  README   1ST   - important information file              19693
2.  SCOPE77A FOR   - Fortran 77 SCOPE source                 30702

The next 4 files are Fortran 77 subroutines used by SCOPE and CAPSIZE.

3.  SCOPE77B FOR                                             24192
4.  SCOPE77C FOR                                             22784
5.  SCOPE77D FOR                                             19712
6.  SCOPE77E FOR                                             14336
7.  AREAD    FOR   - Free-form input routines used by        28288
		     SCOPE, CAPSIZE and KWIKDOSE
8.  CAPSIZE  FOR   - Fortran 77 CAPSIZE source               57836
9.  KWIKDOSE FOR   - Fortran 77 KWIKDOSE source              22547
10. LPRINTER FOR   - Fortran 77 program to print output.       640
11. RSIC     BAT   - batch command file to compile and link    808
		     all subroutines.
12. SCOPE    EXE   - executable SCOPE program.              105229
13. CAPSIZE  EXE   - executable CAPSIZE program.            117457
14. KWIKDOSE EXE   - executable KWIKDOSE program.            71023
15. LPRINTER EXE   - executable LPRINTER program.            20793
16. SCOPE1   INP   - 10 SCOPE sample problems.                6494
17. SCOPE2   INP   - corresponds to tenth sample input of      673
		     of SCOPE1.INP
18. SCOPE3   INP   - same as SCOPE2.INP except for comment    1697
		     cards.
19. SCOPE1   OUT   - output from SCOPE1.INP                 122492
20. SCOPE2   OUT   - output from SCOPE2.INP                  18117
21. SCOPE3   OUT   - output from SCOPE3.INP                  22267

This package requires one 5.25-inch DS/HD diskette or 3 DS/DD diskettes
for transmittal.
120 
laine de lieues au-dessus de la Nouvelle-Orlans. A
part ees points, qui obstruent la libre navigation du
grand fleuve (*), tout son cours est entre les mains des
fdraux.
. Sur les ctes de l'Atlantique et sur mer, la situa-
tion n'a pas notablement chang. Les scessionnistes
ont eu quelques succs de corsaires, entre autres avec
un navire construit en Angleterre, l'Alabama. Ils ont
aussi repris le port de Galveston. Mais le blocus est
toujours aussi rigoureux qu'au dbut, et une rcente
tentative pour le rompre devant Charleston a t si
promptement rprime, qu'elle n'a fait que mettre
mieux en vidence la supriorit maritime bien relle
de l'Union.
La flottille de& Monitors, dont je parlais prcdem-
ment (voir page 81), est actuellement en expdition,
et l'on s'attend  une attaque prochaine contre un des
points importants de la cte.
En rsum, la situation militaire est  ce moment
la suivante :
L'arme du Potomac, sous les ordres du gnral
Hooker, successeur de Burnside, est chelonne 
droite et  gauche de Cenlreville, rduite  l'inaction
par l'tat boueux de la contre  celte saison.
Une vingtaine de mille hommes, sous le gnral
Foster,' menace Richmond de Newbern, dans la Caro-
line du Nord.
(') P. S. Les scessionnistes viennent d'y capturer deux ca-
nonnires fdrales qui avaient franchi la passe de Wicksburg,
le Queen of the West et l'Indianola.
Dave Garrett                                                                  
September 14, 1992
Headquarters, Washington, D.C.
(Phone:  202/453-8400)

RELEASE:  92-146

DEIDRE A. LEE APPOINTED NASA DEPUTY PROCUREMENT CHIEF

     NASA Administrator Daniel S. Goldin announced today the 
appointment of Deidre A. Lee, a veteran aerospace acquisitions 
officer, as Deputy Assistant Administrator for Procurement.  

     Lee, who managed a variety of procurement activities in both 
NASA and the Air Force, currently serves as the Executive Officer 
to NASA's Acting Deputy Administrator Aaron Cohen. 

     "We are very fortunate to have a person with Deidre Lee's 
considerable experience and energy to fill this position at a 
time when we are undertaking major reforms in NASA procurement 
activities," Goldin said.

     Lee joined NASA in 1984 and served in numerous acquisition 
positions at the Johnson Space Center, Houston.  Her final 
assignment there was Chief of Space Shuttle procurement.

     She was assigned to Headquarters, Washington, D.C., in April 
1991, as the Special Assistant to the Assistant Administrator for 
Procurement.  In her next assignment as Deputy Director of the 
Advanced Procurement Planning Division, she managed policy 
development and allocation and control of procurement office 
resources.  

     She also coordinated agency procurement initiatives and 
represented NASA on numerous internal and external teams studying 
key procurement issues.  Most notable were those affecting 
resumed human exploration of the solar system. 

                            - more -

                             - 2 -

     Lee became the deputy's Executive Officer last April.  In 
this capacity she played a significant coordination role in the 
agency's current Red/Blue Team studies to reduce out-year costs 
of major space and aeronautics projects without undermining 
mission objectives.

     While with the Air Force, Lee was involved in major 
procurement activities for the systems and logistics commands and 
for the Pacific Air Forces.

     She holds a masters degree in public administration from the 
University of Oklahoma and was selected by NASA to attend the 
prestigious Middle Management Program of the Graduate School of 
Management of Simmons College, Boston. 

                            - end -
Comment 0412590
From: lasdon2@comcast.net
Sent: Wednesday, July 27, 2005 10:27 PM
To: Rulemaking, TTB
Subject: Notice No. 41: Labeling and Advertising of Wines, Distilled
Spirits and Malt Beverages
U.S.  TTB
 
Dear U.S.  TTB,
Everything I consume, from food to non-alcoholic beverages to medications and even dietary supplements, provides basic consumer facts about the product on the label. Yet I've noticed that my favorite spirits, beer and wine bottles do not contain that information. 
Alcohol beverages are the only major category of consumable product that is largely forbidden by the government from disclosing this kind of helpful information, and that is why I hope the TTB will allow beverage alcohol companies to voluntarily put labels on their products.
Consumers want this information and the industry wants to provide it. Common sense says that these labels should be permitted. I urge you to allow beverage alcohol companies to put basic nutritional information on their packages.
Thank you very much for your consideration.
Sincerely,
Dominic Conway
20409 millhaven st.
Independence, Missouri 64056
 cc: 
Senator Christopher Bond
Senator Jim Talent
Representative Emanuel Cleaver
State Supervisor Dale Roberts
Minutes for 20 Dec 95

Announcements:

	Done with long contacts.  From now on, will have 8+1.5=9.5 hr long
	contacts.

FOT Report

	Uneventful night for S/C

	Completed tape recorder commissioning

	Set values of off pointing flags to

		30 arcsec roll
		1 arcsec pitch/yaw

	and tripped within 2 hrs.  Reset to 

		40 arcsec roll
		2 arcsec pitch/yaw

	and hasn't tripped yet.  This flag is for use by the instruments; it
	has no effect on the S/C.

	MCC2 may occur on the 5th of January.

	Patch for POCC worked

	SOTA has 3 days left

	Request for short contacts during Xmas sent out.

	Did all planned activities

Flight Dynamics report

	There was a report on SOHO Attitude and Momentum Management.  Slides
	will be distributed to the PI teams.  In the slides, roll is measured
	relative to ecliptic north.

	Star magnitude typically within 0.1 mag of catalog.

	Reaction wheels

		Design perturbation torques	Latest estimate

		Tr = 10^-6 Nm			2x10^-6
		Ty = 6x10-6 Nm			2.5x10^-6
		Tz = 6x10-6 Nm			3x10^-6

	Estimate able to support w/o interruption for > 8 weeks

CELIAS
	CETOF switched on successfully
	Detector has 10 cts/sec background rad., which is O.K.
	Temperature elevated by 5deg, which is O.K.
	Reference temperature is 8deg, should be 0-5
	In bakeout phase

Comment from SOTA

	Should be exchange of papers between FOT and SOTA

MDI

	Opened front door for first time
	4deg temp increase, more than expected
	Took first light picture
	Pointing is good.  Offset by 1,2 arcmin.  Will correct today
	Initial checks from focus indicates toward one end rather than middle.
	May be a temperature affect.
	Shutter seemed to stick at first
	Data seen in Palo Alto at same time

SUMER
	Rear slit camera primary goal (pointing) achievable without resolution.
	Commisioned all mechanisms.

LASCO
	Opened all 3 doors for outgassing
	Doing software upload today

UVCS
	Activities postponed because adjusting door apertures
	Review mechanism procedures
	Next is unlocking mechanisms

	Perturbations:

	1st maneuver	Roll	+/- 10 arcsec
			Pitch	+/- 0.4 arcsec (1 Hz)
			Yaw	+/- 0.4 arcsec (1 Hz)

	2nd maneuver	Roll	+/- 15 arcsec
			Pitch	+0.4/-0.2 arcsec (1 Hz)
			Yaw	+/- 0.3 arcsec (1 Hz)

	Rate was 20 deg/min.  Nominal is 10.  Current lowest rate is 5.

SWAN
	Completed coarse pointing activities
	Need to calibrate pointing
	Instrument working perfectly
	Anomaly: Time tag jumped back to Nov 25th.  One bit was reset.  Cause
	is unknown

ERNE
	No change

COSTEP
	Saw reduction in bg after MDI door opening.  Faint reflection from MDI
	door.

Issues

	ESA/MATRA wants impact of Xmas activities on S/C

	C StCyr wants status of lost command problem from CMS.  CMS on
	furlough.

	ECS software had problems.  Some instruments need to restart their
	software.

	Telemetry reformatting software not working well.  Need patch to make
	it more automatic.

	Problem with people going into closet and ECS drawers.

	Experimenters need to determine when they need dedicated time

Clarification from SUMER

	If SUMER gets ESR during bakeout period, then will not close doors.
	Otherwise, would get too hot.