BLASTP 2.0.8 [Jan-05-1999]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= YOL010W YOL010W, Chr XV from 307938-309041
         (367 letters)

Database: nr
           361,503 sequences; 110,384,460 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

gi|2500651|sp|Q08096|RTC1_YEAST RNA 3'-TERMINAL PHOSPHATE CYCLA...   732  0.0
gi|1351630|sp|Q09870|RTC1_SCHPO PROBABLE RNA 3'-TERMINAL PHOSPH...   274  7e-73
gi|2500650|sp|Q23400|RTC1_CAEEL PROBABLE RNA 3'-TERMINAL PHOSPH...   192  2e-48
gi|1330376 (U58758) ZK1127.5 [Caenorhabditis elegans]                120  2e-26
gi|2500649|sp|P56175|RTC1_DROME PROBABLE RNA 3'-TERMINAL PHOSPH...    96  4e-19
gi|3914930|sp|O27937|RTCA_METTH PROBABLE RNA 3'-TERMINAL PHOSPH...    85  5e-16
gi|2500648|sp|O00442|RTC1_HUMAN RNA 3'-TERMINAL PHOSPHATE CYCLA...    85  9e-16
gi|3914932|sp|O28837|RTCA_ARCFU PROBABLE RNA 3'-TERMINAL PHOSPH...    79  5e-14
gi|2500652|sp|Q60335|RTCA_METJA PROBABLE RNA 3'-TERMINAL PHOSPH...    78  9e-14
gi|3914927|sp|O15746|RTC1_DICDI PROBABLE RNA 3'-TERMINAL PHOSPH...    70  3e-11
gi|3676131|emb|CAA21129| (AL031765) 1-evidence=predicted by con...    68  1e-10
gi|3914936|sp|O66884|RTCA_AQUAE PROBABLE RNA 3'-TERMINAL PHOSPH...    66  3e-10
gi|3914934|sp|O59198|RTCA_PYRHO PROBABLE RNA 3'-TERMINAL PHOSPH...    66  4e-10
gi|2507354|sp|P46849|RTCA_ECOLI RNA 3'-TERMINAL PHOSPHATE CYCLA...    50  3e-05

>gi|2500651|sp|Q08096|RTC1_YEAST RNA 3'-TERMINAL PHOSPHATE CYCLASE
           (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2131987|pir||S66692 hypothetical protein YOL010w -
           yeast (Saccharomyces cerevisiae)
           >gi|1419779|emb|CAA99009| (Z74752) ORF YOL010w
           [Saccharomyces cerevisiae]
           Length = 367
           
 Score =  732 bits (1870), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVT 60
           MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVT
Sbjct: 1   MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVT 60

Query: 61  NGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKG 120
           NGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKG
Sbjct: 61  NGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKG 120

Query: 121 ITASHNDAGIEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITM 180
           ITASHNDAGIEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITM
Sbjct: 121 ITASHNDAGIEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITM 180

Query: 181 HEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPG 240
           HEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPG
Sbjct: 181 HEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPG 240

Query: 241 WGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVY 300
           WGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVY
Sbjct: 241 WGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVY 300

Query: 301 MVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIGFT 360
           MVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIGFT
Sbjct: 301 MVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIGFT 360

Query: 361 NTSKKIA 367
           NTSKKIA
Sbjct: 361 NTSKKIA 367

>gi|1351630|sp|Q09870|RTC1_SCHPO PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2130253|pir||S62537 hypothetical protein
           SPAC12G12.06c - fission yeast (Schizosaccharomyces
           pombe) >gi|1052524|emb|CAA91501| (Z66568) SPAC12G12.06c,
           unknown, len: 363 [Schizosaccharomyces pombe]
           Length = 363
           
 Score =  274 bits (693), Expect = 7e-73
 Identities = 154/362 (42%), Positives = 225/362 (61%), Gaps = 14/362 (3%)

Query: 11  FQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYT 70
           F+G +    R+VLATLSG PI++E I   + +PG+KDY+VSFLRL+E +TNGSVIEISYT
Sbjct: 9   FKGCEYLTHRLVLATLSGTPIRVEGIYPDEADPGVKDYQVSFLRLLEKLTNGSVIEISYT 68

Query: 71  GTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGI 130
           GT+ IYRPG I+GG   H CP++K +GYF+EP+L L  F+K   S+   G+T+S+ D G+
Sbjct: 69  GTSFIYRPGNIIGGRVVHDCPTTKGIGYFLEPILILCLFAKTPTSLTLTGVTSSNEDIGV 128

Query: 131 EAIKWGLMPVMEK-FGV-RECALHTLKRGSPPLGGGEVH----LVVDSLIAQPITMHEID 184
           + ++  ++P ++K F V  E  L  LKRGS P GGGEV+    ++ +SL   PI + E  
Sbjct: 129 DVLRTSVLPSLQKRFQVGDELELRILKRGSAPGGGGEVNFLCPVIKESL--PPIRLSEFG 186

Query: 185 RPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGIT 244
           R  +  I G+A STRVSP+  NR+++ A+ VL     +V I  DV RG+  G SPG+ IT
Sbjct: 187 R--VFRIRGIASSTRVSPAFANRLVESARGVLNPFIPDVFIYTDVRRGDECGNSPGYSIT 244

Query: 245 LVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIG 304
           LVA++  KG SY AE  G+AG  PE++G   A +LLE I     V     P  +  M++ 
Sbjct: 245 LVAET-NKGCSYAAEHCGEAGETPEDVGSFCAKKLLEVIESGGCVDPYTQPSTLTGMLLS 303

Query: 305 KEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIGFTNTSK 364
            ED+  + + +  I  + ++ LRD+K +FN E   K ++    E    +  G G+ N ++
Sbjct: 304 SEDVNTIVVGQLGITSQLVVFLRDVKALFNCEYRFKELESGQVE---MSCLGKGYLNVNR 360

Query: 365 KI 366
           +I
Sbjct: 361 RI 362

>gi|2500650|sp|Q23400|RTC1_CAEEL PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           Length = 379
           
 Score =  192 bits (484), Expect = 2e-48
 Identities = 124/376 (32%), Positives = 199/376 (51%), Gaps = 25/376 (6%)

Query: 11  FQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYT 70
           F G   FR+R+  + LSG+PI+I  IR  D  PG++D+E   + L+E VTNG+ +EIS T
Sbjct: 8   FSGCNFFRIRLAYSILSGRPIRIINIRKNDDRPGIRDFESKLIGLLEKVTNGTKVEISRT 67

Query: 71  GTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGI 130
           GT VI+RPG+I GG     C + + + YF+EP+L L+PF K    I  KG+T +  +  +
Sbjct: 68  GTQVIFRPGMITGGVVNLDCGTERCISYFLEPLLLLSPFCKVPMVIKLKGVTNAPGEISV 127

Query: 131 EAIKWGLMPVMEKFGVRE--CALHTLKRGSPPLGGGEVHLVVDSL-IAQPITMHEIDRPI 187
           + +K   + V  KF + +    +    RG  P GGG V      +   +P+   ++ +  
Sbjct: 128 DGMKASWLKVYNKFVLNDEKLDIKIQARGLKPEGGGVVVFTAPIVKTLRPVKRQQVGK-- 185

Query: 188 ISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVA 247
           +  I G AY T+V+PSL  RMID AKK +     +V IT D  +G+  G SPG+G+ L A
Sbjct: 186 VCKIRGQAYVTKVTPSLAYRMIDAAKKAMHGYISDVYITVDQRKGDAGGASPGYGLFLTA 245

Query: 248 QSKQKGWSYFAEDI----GDAG--SIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYM 301
           ++ + G  Y AE I    G++G   +PE++G +    LL++I    A+  +   LA  +M
Sbjct: 246 ETTE-GVIYQAEAISRPKGESGVPILPEDIGIEAGHALLQQIYMGGALDSSAQILASTFM 304

Query: 302 VIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPV------DEAD-----NEDM 350
            +  +D+         +    +  LR +K+ F  E  ++        +EAD      +  
Sbjct: 305 TLCPKDVSHFLYG--PLPMYSVHALRHLKQFFEIEFKMEDFKKTLKEEEADLKTGSADKA 362

Query: 351 IATIKGIGFTNTSKKI 366
           + T  G+G++N +K I
Sbjct: 363 MVTAVGVGYSNLNKTI 378

>gi|1330376 (U58758) ZK1127.5 [Caenorhabditis elegans]
           Length = 303
           
 Score =  120 bits (298), Expect = 2e-26
 Identities = 90/307 (29%), Positives = 151/307 (48%), Gaps = 25/307 (8%)

Query: 80  IIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEAIKWGLMP 139
           +I GG     C + + + YF+EP+L L+PF K    I  KG+T +  +  ++ +K   + 
Sbjct: 1   MITGGVVNLDCGTERCISYFLEPLLLLSPFCKVPMVIKLKGVTNAPGEISVDGMKASWLK 60

Query: 140 VMEKFGVRECALHTL--KRGSPPLGGGEVHLVVDSL-IAQPITMHEIDRPIISSITGVAY 196
           V  KF + +  L      RG  P GGG V      +   +P+   ++ +  +  I G AY
Sbjct: 61  VYNKFVLNDEKLDIKIQARGLKPEGGGVVVFTAPIVKTLRPVKRQQVGK--VCKIRGQAY 118

Query: 197 STRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSY 256
            T+V+PSL  RMID AKK +     +V IT D  +G+  G SPG+G+ L A++ + G  Y
Sbjct: 119 VTKVTPSLAYRMIDAAKKAMHGYISDVYITVDQRKGDAGGASPGYGLFLTAETTE-GVIY 177

Query: 257 FAEDI----GDAG--SIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGR 310
            AE I    G++G   +PE++G +    LL++I    A+  +   LA  +M +  +D+  
Sbjct: 178 QAEAISRPKGESGVPILPEDIGIEAGHALLQQIYMGGALDSSAQILASTFMTLCPKDVSH 237

Query: 311 LRINKEQIDERFIILLRDIKKIFNTEVFLKPV------DEAD-----NEDMIATIKGIGF 359
                  +    +  LR +K+ F  E  ++        +EAD      +  + T  G+G+
Sbjct: 238 FLYG--PLPMYSVHALRHLKQFFEIEFKMEDFKKTLKEEEADLKTGSADKAMVTAVGVGY 295

Query: 360 TNTSKKI 366
           +N +K I
Sbjct: 296 SNLNKTI 302

>gi|2500649|sp|P56175|RTC1_DROME PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           Length = 235
           
 Score = 96.0 bits (235), Expect = 4e-19
 Identities = 74/235 (31%), Positives = 120/235 (50%), Gaps = 26/235 (11%)

Query: 151 LHTLKRGSPPLGGGEVHL---VVDSLIAQPITMHEIDRPIISSITGVAYSTRVSPSLVNR 207
           L  ++RG  PLGGGE+     V  SL A         + ++  I G  Y+ +VSP++ NR
Sbjct: 7   LKVVRRGVAPLGGGEIIFRCPVRKSLRAIQFQ----SQGMVKRIRGTVYACKVSPAMANR 62

Query: 208 MIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSYFA-------ED 260
            ++ AK  +     +V I  D  +G+ SG SPG+GI L+A++   G  + A       E+
Sbjct: 63  TVEAAKGCMLKFLPDVYIYTDQNKGKMSGNSPGFGICLIAETTD-GVCFAADCCSNTREE 121

Query: 261 IGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGRLRINK-EQID 319
             D  SIPE LG++VA +LL+EI +   V  +   LA +Y+ +G++ + +          
Sbjct: 122 SEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAALYIALGQKHVSKFLTGALSNYT 181

Query: 320 ERFIILLRDI----KKIFNTEVFLKPVDEADN----EDMIATIKGIGFTNTSKKI 366
             F+  LRD      K+ N E   +  DEA+N    + ++    GIG+TN +K++
Sbjct: 182 VHFLQHLRDFFSITFKLENPEA--EDEDEAENVRGAQKVLMACVGIGYTNINKRV 234

>gi|3914930|sp|O27937|RTCA_METTH PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2623049 (AE000942) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 337
           
 Score = 85.4 bits (208), Expect = 5e-16
 Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 10/291 (3%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G    R+   LA ++ + +++  IR+     GL    ++ +R +  ++NG++        
Sbjct: 12  GGAVVRVSTALAAVTSRSVRVYNIRARRSRSGLSHQHLTAVRAVARISNGTLRGDELGSM 71

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            + + PG + GG       ++   G  ++ ++  A  S+ +  +   G T        + 
Sbjct: 72  ELEFSPGRVTGGTFNFDVKTAGSTGLVLQAIMVAAAASEGEIDVTVSGGTDVLWAPTCDY 131

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSIT 192
           ++   +PV+E  G     +  ++RG  P GGG VH +++    +PIT+ E +   I ++ 
Sbjct: 132 LREVTIPVLEMMGY-SARIEIIRRGYYPEGGGRVHAIIEPSELRPITLEESE---IHAVR 187

Query: 193 GVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQK 252
           G+++S  +   +  R  + A K+L+    +V+I  +   G       G GITL A+   +
Sbjct: 188 GISHSRNLPVHVAERQAESAMKILRGAGLDVDIMVEDASGP---VGRGSGITLWAEGNTR 244

Query: 253 GWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVI 303
                A  +G  G   E++G + A +LL  I   + + R      I YM +
Sbjct: 245 ---LGAVSLGKPGKRAEKVGSEAARELLGFIESGSPLDRYMGDQIIPYMAL 292

>gi|2500648|sp|O00442|RTC1_HUMAN RNA 3'-TERMINAL PHOSPHATE CYCLASE 1
           (RNA-3'-PHOSPHATE CYCLASE 1) (RNA CYCLASE 1)
           >gi|2125812|emb|CAA72364| (Y11651) phosphate cyclase
           [Homo sapiens]
           Length = 366
           
 Score = 84.7 bits (206), Expect = 9e-16
 Identities = 89/358 (24%), Positives = 156/358 (42%), Gaps = 19/358 (5%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R+   L+ L G P++++KIR+G   PGL+   +S L +I  + +G +       T
Sbjct: 16  GGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGST 75

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            + + P  I GG  T    ++  V   ++  +    F+     +  KG T +     I+ 
Sbjct: 76  EITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGTNAEMAPQIDY 135

Query: 133 IKWGLMPVMEKFG-VRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSI 191
                 P++EKFG +  C + T  RG  P GGGEV +V  S + Q   ++  +R  ++ I
Sbjct: 136 TVMVFKPIVEKFGFIFNCDIKT--RGYYPKGGGEV-IVRMSPVKQLNPINLTERGCVTKI 192

Query: 192 TGVAYSTRVSPSLVNRMIDGA-----KKVLKNLQCEVNITADVWRGENSGKSPGWGITLV 246
            G A+   V P  V + +  A     +K +++L   VNI   V   ++     G GI ++
Sbjct: 193 YGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLY--VNI-QPVQEPKDQAFGNGNGIIII 249

Query: 247 AQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKE 306
           A++   G  +    +G  G   +++G + A  LL  +     V        IV+M +   
Sbjct: 250 AET-STGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMALAN- 307

Query: 307 DIGRLRINKEQIDERFIILLRDIKKIFNTEVFLK---PVDEADNEDMIATIKGIGFTN 361
             G  RI    +       +   ++I   +  +K     ++A  +  I   +GIG TN
Sbjct: 308 --GVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKKSEDEEDAAKDTYIIECQGIGMTN 363

>gi|3914932|sp|O28837|RTCA_ARCFU PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2649133 (AE001004) conserved hypothetical protein
           [Archaeoglobus fulgidus]
           Length = 328
           
 Score = 78.8 bits (191), Expect = 5e-14
 Identities = 71/330 (21%), Positives = 133/330 (39%), Gaps = 15/330 (4%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+ ++GK ++I  IR+    PGL    +  +   + ++N  V  +    T
Sbjct: 12  GGQILRTAVALSCVTGKAVRIRNIRANRPKPGLAAQHLKGIEAAKIISNAEVEGLRIGST 71

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            +++ PG + GG       ++  V    + +L    F+ +  ++   G T       ++ 
Sbjct: 72  EIVFNPGSVRGGNFRVDIGTAGSVTLIFQTVLLPLLFADRDSTLTVTGGTDVAWAPPVDY 131

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSIT 192
            K   +  + + G  EC L  LKRG  P GGG V L V     + +    ID      + 
Sbjct: 132 FKNVTLRALREMGA-ECELEVLKRGYYPKGGGMVRLTVRPAEMKGVVYERID----EIVR 186

Query: 193 GVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQK 252
           GV++   +   +  R    A+  L+       I  +V +G ++G        +V  S  K
Sbjct: 187 GVSHCQNLPGHVAERQASSARNFLEERGIRAEIRTEVLKGLSTGSG------IVLWSGYK 240

Query: 253 GWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGRLR 312
           G S   E    A  + +E  E +  +L+ + +  A +    +P A   M  G+ +     
Sbjct: 241 GGSALGERGKRAEVVGQEAAESLYRELMSDAAFDAHLADQVMPFAA--MARGRTEYTTSE 298

Query: 313 INKEQIDERFII--LLRDIKKIFNTEVFLK 340
           +   Q    ++I   L  + K    ++ +K
Sbjct: 299 VTMHQKSNAYVINTFLGKVVKFEGNKIIIK 328

>gi|2500652|sp|Q60335|RTCA_METJA PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2128089|pir||A64303 hypothetical protein MJ0025 -
           Methanococcus jannaschii >gi|1498784 (U67461)
           hypothetical protein [Methanococcus jannaschii]
           Length = 338
           
 Score = 78.0 bits (189), Expect = 9e-14
 Identities = 72/297 (24%), Positives = 128/297 (42%), Gaps = 13/297 (4%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+ L+ KP+KI  IR    N GL    VS ++ ++ + N  V  ++    
Sbjct: 14  GGQIIRTAVSLSALTQKPVKIINIRKKRKNKGLAPQHVSAVKAVKKLCNAEVFGLNVGSE 73

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            + + P  +     T    ++  +   ++ +L L+    KKF++  KG T       I+ 
Sbjct: 74  ELTFIPSKLSPKDFTIDIGTAGSISLVIQTLLPLSLGINKKFTVKIKGGTDVKRAPPIDY 133

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSIT 192
           +K   + ++  FGV    L  LKRG  P GGGEV   V     +   +  I+    + + 
Sbjct: 134 VKNVTLKILRNFGVL-TELKVLKRGFYPEGGGEVIFEVKPSKIKKFDL--IEHSKSNLVE 190

Query: 193 GVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQK 252
           G++Y   +  S+  RM   A  +L   +   NI  +  +G ++G        +V  +   
Sbjct: 191 GISYVQNLDESIARRMRKKAVDLLNKEKLLPNIKIECSKGISTGAG------IVLWNDTL 244

Query: 253 GWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIG 309
           G S     +G+ G   E + E+   +LL+E     A+ +      I ++  GK  +G
Sbjct: 245 GGSC----LGEKGLRAEIVAERAVNELLKERESGMALDKYMGDQIIPFLAFGKGIVG 297

>gi|3914927|sp|O15746|RTC1_DICDI PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2425127 (AF020279) similar to H. sapiens phosphate
           cyclase encoded by GenBank Accession Number Y11651
           [Dictyostelium discoideum]
           Length = 433
           
 Score = 69.9 bits (168), Expect = 3e-11
 Identities = 82/306 (26%), Positives = 128/306 (41%), Gaps = 23/306 (7%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + LA+L  K I IEKIR     PGLK+   + + L+  +    +   S    
Sbjct: 46  GGQILRNSVALASLFNKAISIEKIRYNRDQPGLKNQHKAGIDLMSRLFKAHLTGCSVGSC 105

Query: 73  TVIYRP--------GIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITAS 124
            + Y+P        G+I   A T    S   +     P L  AP S K   ++  G T  
Sbjct: 106 KLYYQPTQKTIQDDGVI--EADTKTAGSICLMIQVSLPCLIFAPHSTK---MVLGGGTNC 160

Query: 125 HNDAGIEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLI--AQPITM-- 180
                 + I+   +P+    G + C +   KRG  P GGG V L    L     PIT+  
Sbjct: 161 DFAPAADYIQNVFLPIATTMGFK-CEMSIDKRGFYPKGGGAVTLTTQPLTQPLSPITIVN 219

Query: 181 -HEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSP 239
             E++R +I S      S R+SP +  RM + AKK++K    +V++  ++          
Sbjct: 220 KGEVNRIVIKS---YFTSPRISPLVAERMNNTAKKLIKKDFKKVDVETELIDVSKFSFGD 276

Query: 240 GWGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIV 299
           G  I + A + Q G  + A   G  G   E++ E  A  LL+++     +        I+
Sbjct: 277 GTFIEIRAYTDQ-GCIFGATGNGAIGVPAEKVAEDAANSLLKDLQDGGCMDEYLQDQLII 335

Query: 300 YMVIGK 305
           +M + K
Sbjct: 336 FMALAK 341

>gi|3676131|emb|CAA21129| (AL031765) 1-evidence=predicted by
           content; 1-method=genefinder;084; 1-method_score=51.07;
           1-evidence_end; 2-evidence=predicted by match;
           2-match_accession=SWISS-PROT:O00442;
           2-match_description=RNA 3'-TERMINAL PHOSPHATE CYCLAS...
           Length = 361
           
 Score = 67.9 bits (163), Expect = 1e-10
 Identities = 87/363 (23%), Positives = 148/363 (39%), Gaps = 35/363 (9%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+ + GKP+++ KIR+   +PGL    +  L L+  +TN  V+      +
Sbjct: 17  GGQALRNALSLSCILGKPVRVVKIRASRPSPGLSHQHLHGLNLLRDITNADVVGNYLLSS 76

Query: 73  TVIYRPGIIVGG---ASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAG 129
           TV + P  I+       TH   S   +     P+L    F+ +   ++  G T       
Sbjct: 77  TVEFTPRTILDNTYRVETHTAASITLIYQMALPVLL---FAGRPSRLIVSGGTNVDFAPP 133

Query: 130 IEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPI-- 187
           +E ++  L+P ++ FGV    L   + G  P G G   L V     QP+T     + +  
Sbjct: 134 VEYMQEVLLPNLKHFGV-SFDLKVQRYGFYPRGQGRCQLDV-----QPVTKLNSGKLVAF 187

Query: 188 --ISSITGVAY-STRVSPSLVNRMIDGAKKVLKNL----QCEVNITADVWRGENSGKSPG 240
             I S++GVAY + R+  ++   M   A++ +  L    QC +     +          G
Sbjct: 188 GRIKSVSGVAYCAGRLPVNIAIDMQQTAQREIHRLWPSQQCSIE---PIKHSRQKAFHNG 244

Query: 241 WGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVY 300
            GI L+  +        A  +G        LG + +CQL + + K   V        I+Y
Sbjct: 245 AGI-LMTVNTTSDVVLGASALGKKRIDGHVLGSEASCQLGDYMRKQVCVDDYMQDQLIIY 303

Query: 301 MVIGKEDIGR--LRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIG 358
           M +    +GR  +R  K     R  I + +       +V ++P        M+ + KG+G
Sbjct: 304 MALA---VGRSTMRTGKLTNHTRTAINVAEQMTGVKFDVAMEP-----GGQMLVSCKGLG 355

Query: 359 FTN 361
             N
Sbjct: 356 HVN 358

>gi|3914936|sp|O66884|RTCA_AQUAE PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|2983257 (AE000700) hypothetical protein [Aquifex
           aeolicus]
           Length = 360
           
 Score = 66.3 bits (159), Expect = 3e-10
 Identities = 88/362 (24%), Positives = 149/362 (40%), Gaps = 34/362 (9%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+TL   P++I  IR+    PGLK   ++ ++L++      V        
Sbjct: 15  GGQIVRTALFLSTLLQVPVRIYNIRAKREKPGLKRQHLNIVKLLKRFAKAKVKGDELGSI 74

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            + Y+P  +  G       ++  +  F++ +L L+ F   +  I   G T       I+ 
Sbjct: 75  ELEYKPQKLKPGYYEVNFDTAGSIPLFLQTILPLSLFVPGEVVIKVIGGTDVPKSPTIDW 134

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVV-DSLIAQPITMHEIDRPIISSI 191
           +++  +  + K       L  LKRG  P GGG V L V + L  QP  + E+   +   +
Sbjct: 135 VRFVFLHYIYKV-PEFIRLEVLKRGFYPAGGGIVQLSVRNKLEKQPENLQEVKEYLKDKV 193

Query: 192 T---------------GVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSG 236
                            VA+       +  R   GA + LKNL        +V+R   + 
Sbjct: 194 NLYRTERGEIRKIHVFSVAHEELRERKVAERQAKGAIEALKNLGYP---EPEVYRQYANA 250

Query: 237 KSPGWGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPL 296
            S G  IT+  +   KG    A+++G  G + E +G +   +L E+ S  A V R+    
Sbjct: 251 NSIGTSITIWLED-TKGNVLGADNLGKKGKLAEVVGAEAVKKLHEDWSSGATVDRHLADH 309

Query: 297 AIVYM-VIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIK 355
            I  M ++G    G +R+       +F   L  +  I+  E FL  + E D ++ I   +
Sbjct: 310 LIPLMALVG----GEIRV------PQFTGHL--LTNIWVCEQFLGKIFEVDEKEKIVRTQ 357

Query: 356 GI 357
           GI
Sbjct: 358 GI 359

>gi|3914934|sp|O59198|RTCA_PYRHO PROBABLE RNA 3'-TERMINAL PHOSPHATE
           CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           >gi|3257956|gnl|PID|d1031582 (AP000006) 369aa long
           hypothetical phosphate cyclase [Pyrococcus horikoshii]
           Length = 369
           
 Score = 66.0 bits (158), Expect = 4e-10
 Identities = 59/280 (21%), Positives = 122/280 (43%), Gaps = 10/280 (3%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+T++G+P++I  IR+   NPGL+   +  +  ++ + N  V        
Sbjct: 40  GGQILRTSVALSTITGEPVRIVNIRANRPNPGLRPQHLHAILALKHLANAEVKGAHVGSR 99

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            +++ P  +     +    ++  +   ++ +L    F+++K      G T       ++ 
Sbjct: 100 ELVFIPKKLEAKEISIDIGTAGSITLVLQALLPAMVFAREKVKFRITGGTDVSWSPPVDY 159

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSL-IAQPITMHEIDRPIISSI 191
           +    +  +EK G+    +  ++RG  P GGG V   V+     + +   E  R  I  I
Sbjct: 160 LSNVTLFALEKIGIHG-EIRVIRRGHYPKGGGIVEGYVEPWNEKRELVAKEYSR--IIKI 216

Query: 192 TGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQ 251
            G++++T +   +  R    AK  L  L+  + I  ++ R       PG GI + A++  
Sbjct: 217 EGISHATNLPSHVAERQARAAKDELLQLKVPIEIRTEISR----SIGPGSGIVVWAETDC 272

Query: 252 KGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGR 291
                  + +G  G   E +G++ A +LL+++     V +
Sbjct: 273 LRLG--GDALGKKGKPAEIVGKEAAQELLDQLKPGHCVDK 310

>gi|2507354|sp|P46849|RTCA_ECOLI RNA 3'-TERMINAL PHOSPHATE CYCLASE
           (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE)
           Length = 339
           
 Score = 50.0 bits (117), Expect = 3e-05
 Identities = 66/283 (23%), Positives = 117/283 (41%), Gaps = 21/283 (7%)

Query: 13  GSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGT 72
           G Q  R  + L+ ++G+P  I  IR+G   PGL    ++ ++    +   +V        
Sbjct: 16  GGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQ 75

Query: 73  TVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEA 132
            +++RPG + GG       S+      ++ +L    F+     +   G T + +    + 
Sbjct: 76  RLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADF 135

Query: 133 IKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSIT 192
           I+  L P++ K G+ +     L+ G  P GGG V   V S +A   T+   +R  I  + 
Sbjct: 136 IRRVLEPLLAKIGIHQ-QTTLLRHGFYPAGGGVVATEV-SPVASFNTLQLGERGNIVQMR 193

Query: 193 GVAYSTRVSPSLVNRMIDG-AKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQ 251
           G      V   +  R I   A     + Q   N+  D        + PG  ++L  +S+ 
Sbjct: 194 GEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRD--------QGPGNTVSLEVESEN 245

Query: 252 KGWSYFAEDIGDAGSIPEELGEKVACQLLEEISK----SAAVG 290
               +F   +G+         E VA QL++E+ +    +AAVG
Sbjct: 246 ITERFFV--VGE----KRVSAEVVAAQLVKEVKRYLASTAAVG 282

  Database: nr
    Posted date:  Mar 13, 1999  7:20 PM
  Number of letters in database: 110,384,460
  Number of sequences in database:  361,503
  
Lambda     K      H
   0.318    0.137    0.394 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 

Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80147510
Number of Sequences: 361503
Number of extensions: 3519528
Number of successful extensions: 6993
Number of sequences better than 1.0e-03: 14
Number of HSP's better than  0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 6972
Number of HSP's gapped (non-prelim): 14
length of query: 367
length of database: 110384460
effective HSP length: 55
effective length of query: 312
effective length of database: 90501795
effective search space: 28236560040
effective search space used: 28236560040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 104 (44.9 bits)