[ R A D I A T I O N D O S E E S T I M A T E S]{.underline}

[ F O R R A D I O P H A R M A C E U T I C A L S]{.underline}

[ April 30, 1996]{.underline}

[ RADIATION INTERNAL DOSE INFORMATION CENTER]{.underline}

[ OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION]{.underline}

[ Mail Stop 51, P.O. Box 117, OAK RIDGE, TN 37831-0117]{.underline}

[ MICHAEL G. STABIN, Ph.D., CHP]{.underline}

[JAMES B. STUBBS, Ph.D.]{.underline}

[ and RICHARD E. TOOHEY, Ph.D., CHP]{.underline}

[This document contains radiation dose estimates for a number of
radiopharmaceuticals commonly used in nuclear medicine. Radiation dose
estimates are listed for all major source organs, and several other
organs typically of interest. All dose estimates were calculated using
the well known MIRD Technique (Loevinger et al. 1991) as implemented in
the MIRDOSE3 computer code, developed by the Radiation Internal Dose
Information Center. In this code, residence times for source organs are
used with decay data from the MIRD Radionuclide Data and Decay Schemes
(1989) to produce estimates of radiation dose to organs of standardized
phantoms representing individuals of different ages. This document
contains dose estimates only for the adult male phantom in the
Cristy-Eckerman phantom series (Cristy and Eckerman, 1987). The adult
male phantom of the Cristy-Eckerman phantom series is different from the
MIRD 5, or \"Reference Man\" phantom (Snyder et al. 1969) in several
aspects, the most important of which is the difference in the masses and
absorbed fractions for the active (red) marrow. The Cristy-Eckerman
adult male contains only 1120 grams of red marrow, not 1500 grams as in
the MIRD 5 phantom. Also, the absorbed fractions for low energy photons
striking the marrow are different, as suggested by Eckerman (1986).
Other minor differences (1910 gram liver in the Cristy-Eckerman phantom
vs. 1800 in the MIRD 5 phantom, e.g.) exist, but are not likely to
significantly affect dose estimates calculated with the two phantoms.
The results presented here can easily be extended to include other
radiopharmaceuticals or phantoms.]{.underline}

[Assumptions which support each of the dose estimates appears at the
bottom of the table of estimates for a given radiopharmaceutical. In
most cases, the model kinetics or organ residence times are explicitly
given. In the case where a MIRD Dose Estimate Report was used as the
basis for the calculation, reference to the Dose Estimate Report may be
the only citation. The use of the Cristy-Eckerman phantom is noted in
each table. The tables list dose estimates for all important source
organs, the red marrow, bone surfaces, ovaries, testes, and uterus. The
bone, marrow, and gonads are considered important by some in considering
risks of radiation exposures. The doses to the uterus may be used to
estimate the dose to the embryo or fetus, up to about 6 weeks gestation.
Thyroid dose estimates are typically not given for iodine-labeled
pharmaceuticals; it is assumed that there is no free iodide in the
product, or else that the thyroid is completely blocked. Addition of
dose from free iodide may be easily done by using an assumed fraction of
free iodide and adding a contribution based on the doses from sodium
iodide. Similar arguments apply to free pertechnetate in Tc-99m-labeled
pharmaceuticals. ]{.underline}

[Any questions about these estimates, or requests for further
information about any radiopharmaceutical dosimetry matter may be
directed to the Radiation Internal Dose Information Center. The Center
is funded by the Department of Energy to provide information on these
matters to requestors. The Center\'s phone numbers are:]{.underline}

[Richard Toohey 423-576-3448]{.underline}

[Michael Stabin 423-576-3449 (on leave of absence,
8/99---8/01)]{.underline}

[Audrey Stelson 423-576-3450]{.underline}

[Secretary 423-576-3478]{.underline}

[FAX 423-576-8673]{.underline}

[Note: effective 1 October 1999, the area code will change from 423 to
865.]{.underline}

[The Center may also be reached via email to or
stelsona@orau.gov.]{.underline}

[This work was performed for the U.S. DOE under contract
DE-AC05-76OR00033, for the U.S. FDA under Interagency Agreement No. FDA
224-75-3016, DOE 40-286-71, and for the U.S. NRC under Contract No.
L-1699-0.]{.underline}

[REFERENCES]{.underline}

Cristy M, Eckerman KF: [Specific Absorbed Fractions of Energy at Various
Ages from Internal Photon Sources]{.underline}. Parts I‑VII.
ORNL/TM‑8381/V1‑V7. Oak Ridge National Laboratory, Oak Ridge, TN, 1987.

Eckerman KF: Aspects of the Dosimetry of Radionuclides Within the
Skeleton with Particular Emphasis on the Active Marrow. Proc. Fourth
International Radiopharmaceutical Dosimetry Symposium, Oak Ridge
Associated Universities, Oak Ridge, TN 1986. pp 514‑534.

Loevinger R, Budinger T, Watson, E: MIRD Primer for Absorbed Dose
Calculations, Society of Nuclear Medicine, 1991.

[Snyder WS, Ford MR, Warner GG, Fisher Jr. HL: Estimates of Absorbed
Fractions for Monoenergetic Photon Sources Uniformly Distributed in
Various Organs of a Heterogeneous Phantom, J. Nucl. Med. Suppl. No. 3,
August 1969.]{.underline}

Stabin MG: MIRDOSE - Personal Computer Software for Use in Internal Dose
Assessment in Nuclear Medicine. J. Nucl. Med. [37]{.underline}(3),
538-546, March1996.

Watson EE, Stabin MG: MIRD Formulation. Med. Phys. [20]{.underline}(2),
Part 2, 511-514, Mar/Apr 1993.

Weber D, Eckerman KF, Dillman LT, Ryman JC: MIRD: Radionuclide Data and
Decay Schemes, Society of Nuclear Medicine, 1989.

Radiopharmaceuticals considered in this report:

H-3 Water

H-3 Inulin

C-11 Monoxide - 20 s breathhold

C-11 Monoxide - continuous inhalation (1 hr)

N-13 Ammonia

C-14 Inulin

O-15 H2O

O-15 O2

F-18 FDG

F-18 Sodium Fluoride

P-32 Sodium Phosphate

Cr-51 Erythrocytes (RBCs)

Co-57 Vitamin B-12 (Cyanocobalamin)

Co-58 Vitamin B-12 (Cyanocobalamin)

Fe-59 Citrate

Co-60 Vitamin B-12 (Cyanocobalamin)

Ga-67 Citrate

Ga-68 Citrate

Se-75 Selenomethionine

Kr-81m Inhalation

Kr-81m Injections

Oral Administration of Kr‑81m

Rb-82

Sr-85 Nitrate

Tc-99m Albumin Microspheres

Tc-99m Disofenin, Lidofenin and Mebrofenin

Tc-99m DMSA

Tc-99m DTPA (injection)

Tc-99m DTPA (aerosol)

Tc-99m ECD (ethylene cystate dimer)

Tc-99m Exametazime (HMPAO)

Tc-99m Glucoheptonate

Tc-99m HEDP

Tc-99m HMDP

Tc-99m HSA

Tc-99m MAA

Tc-99m MAG3

Tc-99m MDP

Tc-99m MIBI (Cardiolite)

Tc-99m Oral Administrations

Tc-99m Pertechnetate

Tc-99m Pyrophosphate

Tc-99m Red Blood Cells - In vitro Labeling

Tc-99m Red Blood Cells - In vivo Labeling

Tc-99m Sulfur Colloid (Normal Patients)

Tc-99m Sulfur Colloid (Intermediate-to-

Advanced Diffuse Parenchymal Liver Disease)

Tc-99m Teboroxime

Tc-99m White Blood Cells

In-111 DTPA

In-111 Platelets

In-111 Red Blood Cells

In-111 White Blood Cells

I-123 Hippuran

I-123 IMP

I-123 mIBG

I-123 Sodium Iodide

I-124 Sodium Iodide

I-125 Fibrinogen

I-125 IMP

I-125 mIBG

I-125 Sodium Iodide

I-126 Sodium Iodide

I-130 Sodium Iodide

I-131 Hippuran

I-131 HSA

I-131 MAA

I-131 mIBG

I-131 Rose Bengal

I-131 Sodium Iodide

I-131 Sodium Iodide (athyroid individual)

Xe-127 (Breathhold)

Xe-127 (5 minute rebreathing)

Xe-127 (10 minute rebreathing)

Xe-133 (Breathhold)

Xe-133 (5 minute rebreathing)

Xe-133 (10 minute rebreathing)

Xe-133 Injections

Hg-197 Chlormerodrin

Au-198 Colloid

Tl-201 Chloride (plus contaminants)

[`	``March 18, 1993`]{.underline}

[`	``Radiation Dose Estimates for H-3 Water*`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              1.5E-02            5.7E-02`]{.underline}

[`Brain                                 1.5E-02            5.7E-02`]{.underline}

[`Breasts                               1.5E-02            5.7E-02`]{.underline}

[`Gallbladder Wall                      1.5E-02            5.7E-02`]{.underline}

[`LLI Wall                              1.5E-02            5.7E-02`]{.underline}

[`Small Intestine                       1.5E-02            5.7E-02`]{.underline}

[`Stomach                               1.5E-02            5.7E-02`]{.underline}

[`ULI Wall                              1.5E-02            5.7E-02`]{.underline}

[`Heart Wall                            1.5E-02            5.7E-02`]{.underline}

[`Kidneys                               1.5E-02            5.7E-02`]{.underline}

[`Liver                                 1.5E-02            5.7E-02`]{.underline}

[`Lungs                                 1.5E-02            5.7E-02`]{.underline}

[`Muscle                                1.5E-02            5.7E-02`]{.underline}

[`Ovaries                               1.5E-02            5.7E-02`]{.underline}

[`Pancreas                              1.5E-02            5.7E-02`]{.underline}

[`Red Marrow                            2.0E-02            7.5E-02`]{.underline}

[`Bone Surfaces                         1.4E-02            5.1E-02`]{.underline}

[`Skin                                  1.5E-02            5.7E-02`]{.underline}

[`Spleen                                1.5E-02            5.7E-02`]{.underline}

[`Testes                                1.5E-02            5.7E-02`]{.underline}

[`Thymus                                1.5E-02            5.7E-02`]{.underline}

[`Thyroid                               1.5E-02            5.7E-02`]{.underline}

[`Urinary Bladder Wall                  1.6E-02            6.1E-02`]{.underline}

[`Uterus                                1.5E-02            5.7E-02`]{.underline}

[`Effective Dose Equivalent             1.6E-02 mSv/MBq    5.9E-02 rem/mCi`]{.underline}

[`* Based on model in ICRP 53.`]{.underline}

[`Dynamic bladder model with 4.8-hour voiding interval`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	March 18, 1993

[`	``Radiation Dose Estimates for H-3 Inulin*`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              1.0E-04            3.8E-04`]{.underline}

[`Brain                                 1.0E-04            3.8E-04`]{.underline}

[`Breasts                               1.0E-04            3.8E-04`]{.underline}

[`Gallbladder Wall                      1.0E-04            3.8E-04`]{.underline}

[`LLI Wall                              1.0E-04            3.8E-04`]{.underline}

[`Small Intestine                       1.0E-04            3.8E-04`]{.underline}

[`Stomach                               1.0E-04            3.8E-04`]{.underline}

[`ULI Wall                              1.0E-04            3.8E-04`]{.underline}

[`Heart Wall                            1.0E-04            3.8E-04`]{.underline}

[`Kidneys                               1.0E-03            3.8E-03`]{.underline}

[`Liver                                 1.0E-04            3.8E-04`]{.underline}

[`Lungs                                 1.0E-04            3.8E-04`]{.underline}

[`Muscle                                1.0E-04            3.8E-04`]{.underline}

[`Ovaries                               1.0E-04            3.8E-04`]{.underline}

[`Pancreas                              1.0E-04            3.8E-04`]{.underline}

[`Red Marrow                            1.4E-04            5.0E-04`]{.underline}

[`Bone Surfaces                         9.3E-05            3.4E-04`]{.underline}

[`Skin                                  1.0E-04            3.8E-04`]{.underline}

[`Spleen                                1.0E-04            3.8E-04`]{.underline}

[`Testes                                1.0E-04            3.8E-04`]{.underline}

[`Thymus                                1.0E-04            3.8E-04`]{.underline}

[`Thyroid                               1.0E-04            3.8E-04`]{.underline}

[`Urinary Bladder Wall                  2.4E-02            9.0E-02`]{.underline}

[`Uterus                                1.0E-04            3.8E-04`]{.underline}

[`Effective Dose Equivalent             1.6E-03 mSv/MBq    6.0E-03 rem/mCi`]{.underline}

[`* Based on the model in ICRP 53.`]{.underline}

[`Dynamic bladder model with 4.8-hour voiding interval`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	March 18, 1993

[`	``Radiation Dose Estimates for C-11 Carbon Monoxide*`]{.underline}

[`	``Single inhalation with 20 s breathhold`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              6.1E-03            2.3E-02`]{.underline}

[`Brain                                 1.1E-03            3.9E-03`]{.underline}

[`Breasts                               2.3E-03            8.7E-03`]{.underline}

[`Gallbladder Wall                      2.9E-03            1.1E-02`]{.underline}

[`LLI Wall                              2.3E-03            8.5E-03`]{.underline}

[`Small Intestine                       2.4E-03            9.0E-03`]{.underline}

[`Stomach                               2.7E-03            1.0E-02`]{.underline}

[`ULI Wall                              2.4E-03            8.9E-03`]{.underline}

[`Heart Wall                            2.0E-02            7.2E-02`]{.underline}

[`Kidneys                               6.8E-03            2.5E-02`]{.underline}

[`Liver                                 4.9E-03            1.8E-02`]{.underline}

[`Lungs                                 1.4E-02            5.2E-02`]{.underline}

[`Muscle                                2.2E-03            8.2E-03`]{.underline}

[`Ovaries                               2.4E-03            8.8E-03`]{.underline}

[`Pancreas                              3.2E-03            1.2E-02`]{.underline}

[`Red Marrow                            5.4E-03            2.0E-02`]{.underline}

[`Bone Surfaces                         3.2E-03            1.2E-02`]{.underline}

[`Skin                                  1.8E-03            6.5E-03`]{.underline}

[`Spleen                                1.3E-02            4.8E-02`]{.underline}

[`Testes                                1.9E-03            7.1E-03`]{.underline}

[`Thymus                                3.4E-03            1.3E-02`]{.underline}

[`Thyroid                               4.8E-03            1.8E-02`]{.underline}

[`Urinary Bladder Wall                  2.2E-03            8.2E-03`]{.underline}

[`Uterus                                2.4E-03            8.7E-03`]{.underline}

[`Effective Dose Equivalent             6.5E-03 mSv/MBq    2.4E-02 rem/mCi`]{.underline}

[`* Based on model in ICRP 53.`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	March 18, 1993

[`	``Radiation Dose Estimates for C-11 Carbon Monoxide*`]{.underline}

[`	``Continuous Inhalation for 1 hr`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              4.0E-03            1.5E-02`]{.underline}

[`Brain                                 6.9E-04            2.6E-03`]{.underline}

[`Breasts                               1.5E-03            5.7E-03`]{.underline}

[`Gallbladder Wall                      1.9E-03            6.9E-03`]{.underline}

[`LLI Wall                              1.5E-03            5.6E-03`]{.underline}

[`Small Intestine                       1.6E-03            5.9E-03`]{.underline}

[`Stomach                               1.8E-03            6.5E-03`]{.underline}

[`ULI Wall                              1.6E-03            5.8E-03`]{.underline}

[`Heart Wall                            1.3E-02            4.7E-02`]{.underline}

[`Kidneys                               4.5E-03            1.7E-02`]{.underline}

[`Liver                                 3.2E-03            1.2E-02`]{.underline}

[`Lungs                                 9.3E-03            3.4E-02`]{.underline}

[`Muscle                                1.4E-03            5.4E-03`]{.underline}

[`Ovaries                               1.6E-03            5.8E-03`]{.underline}

[`Pancreas                              2.1E-03            7.8E-03`]{.underline}

[`Red Marrow                            3.6E-03            1.3E-02`]{.underline}

[`Bone Surfaces                         2.1E-03            7.7E-03`]{.underline}

[`Skin                                  1.1E-03            4.2E-03`]{.underline}

[`Spleen                                8.5E-03            3.1E-02`]{.underline}

[`Testes                                1.2E-03            4.6E-03`]{.underline}

[`Thymus                                2.2E-03            8.2E-03`]{.underline}

[`Thyroid                               3.2E-03            1.2E-02`]{.underline}

[`Urinary Bladder Wall                  1.4E-03            5.4E-03`]{.underline}

[`Uterus                                1.6E-03            5.7E-03`]{.underline}

[`Effective Dose Equivalent             4.3E-03 mSv/MBq    1.6E-02 rem/mCi`]{.underline}

[`* Based on model in ICRP 53.`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	September 18, 1992

    	Radiation Dose Estimates for N-13 Ammonia

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              1.7E-03            6.2E-03`]{.underline}

[`Brain                                 4.7E-03            1.7E-02`]{.underline}

[`Breasts                               1.3E-03            4.7E-03`]{.underline}

[`Gallbladder Wall                      1.9E-03            6.9E-03`]{.underline}

[`LLI Wall                              1.7E-03            6.2E-03`]{.underline}

[`Small Intestine                       1.7E-03            6.2E-03`]{.underline}

[`Stomach                               1.6E-03            5.9E-03`]{.underline}

[`ULI Wall                              1.7E-03            6.2E-03`]{.underline}

[`Heart Wall                            1.6E-03            5.9E-03`]{.underline}

[`Kidneys                               1.6E-03            5.9E-03`]{.underline}

[`Liver                                 3.8E-03            1.4E-02`]{.underline}

[`Lungs                                 1.5E-03            5.4E-03`]{.underline}

[`Muscle                                1.4E-03            5.3E-03`]{.underline}

[`Ovaries                               1.7E-03            6.4E-03`]{.underline}

[`Pancreas                              1.7E-03            6.4E-03`]{.underline}

[`Red Marrow                            1.8E-03            6.6E-03`]{.underline}

[`Bone Surfaces                         1.5E-03            5.6E-03`]{.underline}

[`Skin                                  1.2E-03            4.6E-03`]{.underline}

[`Spleen                                1.5E-03            5.7E-03`]{.underline}

[`Testes                                1.4E-03            5.4E-03`]{.underline}

[`Thymus                                1.5E-03            5.4E-03`]{.underline}

[`Thyroid                               1.5E-03            5.5E-03`]{.underline}

[`Urinary Bladder Wall                  6.9E-03            2.6E-02`]{.underline}

[`Uterus                                1.8E-03            6.8E-03`]{.underline}

[`Effective Dose Equivalent             2.2E-03 mSv/MBq    8.3E-03 rem/mCi`]{.underline}

[`Based on distribution data gathered in human subjects by Lockwood et al. (``J Clin Invest`` 63:449-460, 1979).  Assumed distribution and retention:`]{.underline}

[`  Brain        6.9%      T`]{.underline}~[`b`]{.underline}~[` = `¥]{.underline}

[`  Liver        7.1%      T`]{.underline}~[`b`]{.underline}~[` = `¥]{.underline}

[`  Total Body    94%      T`]{.underline}~[`b`]{.underline}~[` = `¥]{.underline}

[`                 6%      T`]{.underline}~[`b`]{.underline}~[` = 10 min`]{.underline}

[`6% of material cleared through urinary bladder, T`]{.underline}~[`b`]{.underline}~[` = 10 min.  Bladder voiding`]{.underline}

[`interval 4.8 hours.`]{.underline}

[`Dynamic bladder model with 4.8-hour voiding interval.  Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients,`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    March 18, 1993

[`	``Radiation Dose Estimates for C-14 Inulin*`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              9.0E-04            3.3E-03`]{.underline}

[`Brain                                 9.0E-04            3.3E-03`]{.underline}

[`Breasts                               9.0E-04            3.3E-03`]{.underline}

[`Gallbladder Wall                      9.0E-04            3.3E-03`]{.underline}

[`LLI Wall                              9.0E-04            3.3E-03`]{.underline}

[`Small Intestine                       9.0E-04            3.3E-03`]{.underline}

[`Stomach                               9.0E-04            3.3E-03`]{.underline}

[`ULI Wall                              9.0E-04            3.3E-03`]{.underline}

[`Heart Wall                            9.0E-04            3.3E-03`]{.underline}

[`Kidneys                               8.9E-03            3.3E-02`]{.underline}

[`Liver                                 9.0E-04            3.3E-03`]{.underline}

[`Lungs                                 9.0E-04            3.3E-03`]{.underline}

[`Muscle                                9.0E-04            3.3E-03`]{.underline}

[`Ovaries                               9.0E-04            3.3E-03`]{.underline}

[`Pancreas                              9.0E-04            3.3E-03`]{.underline}

[`Red Marrow                            1.2E-03            4.4E-03`]{.underline}

[`Bone Surfaces                         8.1E-04            3.0E-03`]{.underline}

[`Skin                                  9.0E-04            3.3E-03`]{.underline}

[`Spleen                                9.0E-04            3.3E-03`]{.underline}

[`Testes                                9.0E-04            3.3E-03`]{.underline}

[`Thymus                                9.0E-04            3.3E-03`]{.underline}

[`Thyroid                               9.0E-04            3.3E-03`]{.underline}

[`Urinary Bladder Wall                  2.1E-01            7.9E-01`]{.underline}

[`Uterus                                9.0E-04            3.3E-03`]{.underline}

[`Effective Dose Equivalent             1.4E-02 mSv/MBq    5.3E-02 rem/mCi`]{.underline}

[`* Based on the model in ICRP 53.`]{.underline}

[`Dynamic bladder model with 4.8-hour voiding interval`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

[`February 22, 1993`]{.underline}

[`	``Radiation Dose Estimates for O-15 H2O`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              1.3E-03            4.8E-03`]{.underline}

[`Brain                                 1.3E-03            4.9E-03`]{.underline}

[`Breasts                               3.0E-04            1.1E-03`]{.underline}

[`Gallbladder Wall                      4.5E-04            1.7E-03`]{.underline}

[`LLI Wall                              7.4E-04            2.7E-03`]{.underline}

[`Small Intestine                       9.3E-04            3.5E-03`]{.underline}

[`Stomach                               5.3E-04            1.9E-03`]{.underline}

[`ULI Wall                              7.0E-04            2.6E-03`]{.underline}

[`Heart Wall                            2.2E-03            8.2E-03`]{.underline}

[`Kidneys                               1.9E-03            7.2E-03`]{.underline}

[`Liver                                 1.5E-03            5.6E-03`]{.underline}

[`Lungs                                 1.9E-03            6.9E-03`]{.underline}

[`Muscle                                2.7E-04            1.0E-03`]{.underline}

[`Ovaries                               3.6E-04            1.3E-03`]{.underline}

[`Pancreas                              1.6E-03            5.9E-03`]{.underline}

[`Red Marrow                            9.0E-04            3.3E-03`]{.underline}

[`Bone Surfaces                         5.2E-04            1.9E-03`]{.underline}

[`Skin                                  2.6E-04            9.8E-04`]{.underline}

[`Spleen                                1.6E-03            5.8E-03`]{.underline}

[`Testes                                6.7E-04            2.5E-03`]{.underline}

[`Thymus                                3.6E-04            1.3E-03`]{.underline}

[`Thyroid                               1.7E-03            6.3E-03`]{.underline}

[`Urinary Bladder Wall                  2.2E-04            8.1E-04`]{.underline}

[`Uterus                                3.4E-04            1.3E-03`]{.underline}

[`Effective Dose Equivalent             1.1E-03 mSv/MBq    4.2E-03 rem/mCi`]{.underline}

[`Based on data derived from a blood flow-based model of water distribution.  `]{.underline}

[`Assumed residence times:`]{.underline}

[`Adrenals         :   3.92E-05 hr       Lungs             :   3.80E-03 hr `]{.underline}

[`Brain            :   3.48E-03 hr       Muscle            :   9.72E-03 hr `]{.underline}

[`LLI              :   3.22E-04 hr       Pancreas          :   2.83E-04 hr `]{.underline}

[`Small Intestine  :   1.28E-03 hr       Red Marrow        :   1.59E-03 hr `]{.underline}

[`Stomach          :   2.87E-04 hr       Cort Bone         :   1.50E-03 hr `]{.underline}

[`ULI              :   4.22E-04 hr       Canc Bone         :   3.75E-04 hr `]{.underline}

[`Heart Chambers   :   1.70E-03 hr       Spleen            :   5.50E-04 hr `]{.underline}

[`Heart Wall       :   8.42E-04 hr       Testes            :   5.14E-05 hr `]{.underline}

[`Kidneys          :   1.15E-03 hr       Thyroid           :   7.47E-05 hr `]{.underline}

[`Liver            :   5.17E-03 hr       Urinary Bl Cont   :   9.44E-06 hr `]{.underline}

[`                                       Remainder         :   1.63E-02 hr `]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	February 23, 1993

[`	``Radiation Dose Estimates for O-15 O2`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              3.4E-04            1.3E-03`]{.underline}

[`Brain                                 5.2E-04            1.9E-03`]{.underline}

[`Breasts                               2.8E-04            1.1E-03`]{.underline}

[`Gallbladder Wall                      3.0E-04            1.1E-03`]{.underline}

[`LLI Wall                              2.5E-04            9.4E-04`]{.underline}

[`Small Intestine                       2.6E-04            9.8E-04`]{.underline}

[`Stomach                               2.9E-04            1.1E-03`]{.underline}

[`ULI Wall                              2.6E-04            9.8E-04`]{.underline}

[`Heart Wall                            1.5E-03            5.6E-03`]{.underline}

[`Kidneys                               6.9E-04            2.6E-03`]{.underline}

[`Liver                                 5.5E-04            2.0E-03`]{.underline}

[`Lungs                                 4.6E-03            1.7E-02`]{.underline}

[`Muscle                                2.6E-04            9.5E-04`]{.underline}

[`Ovaries                               7.6E-04            2.8E-03`]{.underline}

[`Pancreas                              3.3E-04            1.2E-03`]{.underline}

[`Red Marrow                            3.3E-04            1.2E-03`]{.underline}

[`Bone Surfaces                         2.6E-04            9.6E-04`]{.underline}

[`Skin                                  2.2E-04            8.1E-04`]{.underline}

[`Spleen                                1.1E-03            4.2E-03`]{.underline}

[`Testes                                3.2E-04            1.2E-03`]{.underline}

[`Thymus                                3.5E-04            1.3E-03`]{.underline}

[`Thyroid                               2.6E-04            9.7E-04`]{.underline}

[`Urinary Bladder Wall                  2.5E-04            9.3E-04`]{.underline}

[`Uterus                                2.6E-04            9.7E-04`]{.underline}

[`Effective Dose Equivalent             1.1E-03 mSv/MBq    4.1E-03 rem/mCi`]{.underline}

[`* Based on distribution data of Bigler and Sgouros (``J Nucl Med`` 24(5):431-`]{.underline}

[`  437, 1983).  Cumulated activities in their Table 3 assumed to be for 8400 MBq`]{.underline}

[`  (227 mCi).`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

    	September 18, 1992

[`	``Radiation Dose Estimates for F-18 FDG`]{.underline}

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                              1.3E-02            4.9E-02`]{.underline}

[`Brain                                 1.9E-02            7.0E-02`]{.underline}

[`Breasts                               9.2E-03            3.4E-02`]{.underline}

[`Gallbladder Wall                      1.4E-02            5.0E-02`]{.underline}

[`LLI Wall                              1.7E-02            6.1E-02`]{.underline}

[`Small Intestine                       1.4E-02            5.1E-02`]{.underline}

[`Stomach                               1.3E-02            4.7E-02`]{.underline}

[`ULI Wall                              1.3E-02            4.9E-02`]{.underline}

[`Heart Wall                            6.0E-02            2.2E-01`]{.underline}

[`Kidneys                               2.0E-02            7.4E-02`]{.underline}

[`Liver                                 1.6E-02            5.8E-02`]{.underline}

[`Lungs                                 1.7E-02            6.4E-02`]{.underline}

[`Muscle                                1.1E-02            4.2E-02`]{.underline}

[`Ovaries                               1.7E-02            6.3E-02`]{.underline}

[`Pancreas                              2.6E-02            9.6E-02`]{.underline}

[`Red Marrow                            1.3E-02            4.8E-02`]{.underline}

[`Bone Surfaces                         1.2E-02            4.3E-02`]{.underline}

[`Skin                                  8.4E-03            3.1E-02`]{.underline}

[`Spleen                                3.7E-02            1.4E-01`]{.underline}

[`Testes                                1.3E-02            4.8E-02`]{.underline}

[`Thymus                                1.2E-02            4.4E-02`]{.underline}

[`Thyroid                               1.0E-02            3.9E-02`]{.underline}

[`Urinary Bladder Wall                  1.9E-01            7.0E-01`]{.underline}

[`Uterus                                2.3E-02            8.5E-02`]{.underline}

[`Effective Dose Equivalent             3.0E-02 mSv/MBq    1.1E-01 rem/mCi`]{.underline}

[`Based on the distribution data gathered in dogs by Gallagher et al. (JNM 18(10):990-996) and assuming a 1.83 hour effective half time, except for the brain and urinary bladder, for which the assumptions of Jones et al. (JNM 23(7):613-617), based on data gathered in human subjects, were used.`]{.underline}

[`Dynamic bladder model with 4.8-hour voiding interval`]{.underline}

[`Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)`]{.underline}

[`The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.`]{.underline}

[`Source: Radiation Internal Dose`]{.underline}

[`        Information Center`]{.underline}

                                February 27, 1995

    	Radiation Dose Estimates for F-18 Sodium Fluoride

[`                                       ``Estimated Radiation Dose`]{.underline}

[`                                        ``mGy``                ``rad``  `]{.underline}

[`ORGAN``                                  `` MBq ``              `` mCi `` `]{.underline}

[`Adrenals                             6.2E-03            2.3E-02  `]{.underline}

[`Brain                                5.6E-03            2.1E-02  `]{.underline}

[`Breasts                              2.8E-03            1.0E-02  `]{.underline}

[`Gallbladder Wall                     4.4E-03            1.6E-02  `]{.underline}

[`LLI Wall                             1.2E-02            4.3E-02  `]{.underline}

[`Small Intestine                      6.6E-03            2.5E-02  `]{.underline}

[`Stomach                              3.8E-03            1.4E-02  `]{.underline}

[`ULI Wall                             5.8E-03            2.1E-02  `]{.underline}

[`Heart Wall                           3.9E-03            1.5E-02  `]{.underline}

[`Kidneys                              1.9E-02            7.1E-02  `]{.underline}

[`Liver                                4.0E-03            1.5E-02  `]{.underline}

[`Lungs                                4.1E-03            1.5E-02  `]{.underline}

[`Muscle                               6.0E-03            2.2E-02  `]{.underline}

[`Ovaries                              1.1E-02            3.9E-02  `]{.underline}

[`Pancreas                             4.8E-03            1.8E-02  `]{.underline}

[`Red Marrow                           2.8E-02            1.0E-01  `]{.underline}

[`Bone Surfaces                        6.0E-02            2.2E-01  `]{.underline}

[`Skin                                 4.0E-03            1.5E-02  `]{.underline}

[`Spleen                               4.2E-03            1.5E-02  `]{.underline}

[`Testes                               7.8E-03            2.9E-02  `]{.underline}

[`Thymus                               3.5E-03            1.3E-02  `]{.underline}

[`Thyroid                              4.4E-03            1.6E-02  `]{.underline}

[`Urinary Bladder Wall                 2.5E-01            9.1E-01  `]{.underline}

[`Uterus                               1.9E-02            7.0E-02  `]{.underline}

[`Effective Dose Equivalent            2.7E-02 mSv/MBq    1.0E-01 rem/mCi`]{.underline}

[`Biological model:  ICRP 53 model (data gathered in humans)`]{.underline}

[`Kidney``	``	``	`τ` = 0.025 hours`]{.underline}

[`Cortical bone``	``	``25%``	`` T`]{.underline}~[`b`]{.underline}~[` = 0.333 hours (uptake)``	`` T`]{.underline}~[`b`]{.underline}~[` = `¥` (washout)`]{.underline}

[`Cancellous bone``	``      25%``	`` T`]{.underline}~[`b`]{.underline}~[` = 0.333 hours (uptake)``	`` T`]{.underline}~[`b`]{.underline}~[` = `¥` (washout)`]{.underline}

[`Total body``	``	``    12.5%    T`]{.underline}~[`b`]{.underline}~[` = 0.167 hours,``	``      37.5%  T`]{.underline}~[`b`]{.underline}~[` = 3.2 hours`]{.underline}

[`    50.0%    T`]{.underline}~[`b`]{.underline}~[` = `¥]{.underline}

[`Dynamic Bladder Model Used  (4.80 hr void)`]{.underline}

[`      12.50%     T`]{.underline}~[`b`]{.underline}~[` =  0.167 hr`]{.underline}

[`      37.50%     T`]{.underline}~[`b`]{.underline}~[` =  3.2   hr`]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

                             February 27, 1995

            Radiation Dose Estimates for P-32 Sodium Phosphate          

`                                      `[`Estimated Radiation Dose`]{.underline}

`                                       `[`mGy`]{.underline}`                `[`rad`]{.underline}`  `

[`ORGAN`]{.underline}`                                `[`  MBq  `]{.underline}`            `[`  mCi  `]{.underline}

    Adrenals                             7.6E-04            2.8E-03  

    Brain                                7.6E-04            2.8E-03  

    Breasts                              7.6E-04            2.8E-03  

    Gallbladder Wall                     7.6E-04            2.8E-03  

    LLI Wall                             7.6E-04            2.8E-03  

    Small Intestine                      7.6E-04            2.8E-03  

    Stomach                              7.6E-04            2.8E-03  

    ULI Wall                             7.6E-04            2.8E-03  

    Heart Wall                           7.6E-04            2.8E-03  

    Kidneys                              7.6E-04            2.8E-03  

    Liver                                7.6E-04            2.8E-03  

    Lungs                                7.6E-04            2.8E-03  

    Muscle                               7.6E-04            2.8E-03  

    Ovaries                              7.6E-04            2.8E-03  

    Pancreas                             7.6E-04            2.8E-03  

    Red Marrow                           7.6E+00            2.8E+01  

    Bone Surfaces                        1.0E+01            3.7E+01  

    Skin                                 7.6E-04            2.8E-03  

    Spleen                               7.6E-04            2.8E-03  

    Testes                               7.6E-04            2.8E-03  

    Thymus                               7.6E-04            2.8E-03  

    Thyroid                              7.6E-04            2.8E-03  

    Urinary Bladder Wall                 7.6E-04            2.8E-03  

    Uterus                               7.6E-04            2.8E-03  

    Effective Dose Equivalent            1.2E+00 mSv/MBq    4.5E+00 rem/mCi

    Based on model in ICRP 30 (data gathered in humans).  Assumed distribution and retention:

`Cortical Bone       15%  T`~`b`~` = `¥

`Cancellous Bone     15%  T`~`b`~` = `¥

`Remainder           14%  T`~`b`~` = 12 hr      14%  T`~`b`~` = 48 hr     42%  T`~`b`~` = 456 hr`

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    July 19, 1995

    Radiation Dose Estimates for the Cr-51 RBCs (Erythrocytes)

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.0E-01 7.6E-01 ]{.underline}

[Brain 3.3E-02 1.2E-01 ]{.underline}

[Breasts 8.4E-02 3.1E-01 ]{.underline}

[Gallbladder Wall 1.3E-01 5.0E-01 ]{.underline}

[LLI Wall 8.7E-02 3.2E-01 ]{.underline}

[Small Intestine 9.8E-02 3.6E-01 ]{.underline}

[Stomach 1.4E-01 5.1E-01 ]{.underline}

[ULI Wall 9.9E-02 3.7E-01 ]{.underline}

[Heart Wall 5.0E-01 1.9E+00 ]{.underline}

[Kidneys 2.2E-01 8.1E-01 ]{.underline}

[Liver 2.4E-01 8.9E-01 ]{.underline}

[Lungs 3.2E-01 1.2E+00 ]{.underline}

[Muscle 8.3E-02 3.1E-01 ]{.underline}

[Ovaries 9.2E-02 3.4E-01 ]{.underline}

[Pancreas 1.9E-01 7.1E-01 ]{.underline}

[Red Marrow 1.2E-01 4.4E-01 ]{.underline}

[Bone Surfaces 1.2E-01 4.4E-01 ]{.underline}

[Skin 5.6E-02 2.1E-01 ]{.underline}

[Spleen 1.6E+00 5.8E+00 ]{.underline}

[Testes 6.4E-02 2.4E-01 ]{.underline}

[Thymus 1.3E-01 5.0E-01 ]{.underline}

[Thyroid 1.3E-01 4.7E-01 ]{.underline}

[Urinary Bladder Wall 8.2E-02 3.0E-01 ]{.underline}

[Uterus 9.1E-02 3.4E-01 ]{.underline}

[Total Body 9.6E-02 3.5E-01 ]{.underline}

[Effective Dose Equivalent 2.6E-01 mSv/MBq 9.6E-01 rem/mCi]{.underline}

[Biological model based on ICRP 53. The activity in cortical and
trabecular bone was assumed to be distributed in the bone volume.
Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[Residence Times:]{.underline}

[ Adrenals 3.76E-01 hr Red Marrow 2.73E+01 hr]{.underline}

[ Brain 3.76E+00 hr Cort Bone 1.33E+01 hr]{.underline}

[ Heart Contents 6.03E+01 hr Trab Bone 3.00E+00 hr]{.underline}

[ Heart Wall 7.45E+00 hr Spleen 6.24E+01 hr]{.underline}

[ Kidneys 8.46E+00 hr Thyroid 4.40E-01 hr]{.underline}

     Liver               5.75E+01 hr	Remainder           4.24E+02 hr

     Lungs               6.39E+01 hr

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information to individual patients.

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Co-57 Vitamin B-12
(Cyanocobalamin)]{.underline}

[ Estimated Radiation Dose (mGy/MBq) ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ORGAN Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Adrenals 4.7E+00 6.0E-01 3.1E+00 4.1E-01]{.underline}

[Brain 6.6E-01 8.5E-02 4.4E-01 5.4E-02]{.underline}

[Breasts 1.1E+00 1.5E-01 7.6E-01 9.7E-02]{.underline}

[Gallbladder Wall 8.6E+00 1.1E+00 5.7E+00 7.8E-01]{.underline}

[LLI Wall 1.3E+00 1.4E+00 9.8E-01 1.4E+00]{.underline}

[Small Intestine 1.8E+00 4.0E-01 1.2E+00 3.3E-01]{.underline}

[Stomach 2.0E+00 3.1E-01 1.3E+00 2.3E-01]{.underline}

[ULI Wall 2.5E+00 8.0E-01 1.7E+00 7.0E-01]{.underline}

[Heart Wall 2.9E+00 3.7E-01 1.9E+00 2.5E-01]{.underline}

[Kidneys 3.4E+00 4.4E-01 2.3E+00 3.1E-01]{.underline}

[Liver 3.5E+01 4.4E+00 2.3E+01 3.0E+00]{.underline}

[Lungs 2.6E+00 3.3E-01 1.7E+00 2.2E-01]{.underline}

[Muscle 1.4E+00 1.9E-01 9.0E-01 1.3E-01]{.underline}

[Ovaries 1.3E+00 2.9E-01 8.5E-01 2.4E-01]{.underline}

[Pancreas 4.3E+00 5.6E-01 2.9E+00 3.8E-01]{.underline}

[Red Marrow 1.5E+00 2.2E-01 1.0E+00 1.5E-01]{.underline}

[Bone Surfaces 2.5E+00 3.4E-01 1.6E+00 2.3E-01]{.underline}

[Skin 8.2E-01 1.1E-01 5.5E-01 7.3E-02]{.underline}

[Spleen 1.4E+00 1.9E-01 9.5E-01 1.3E-01]{.underline}

[Testes 6.9E-01 1.0E-01 4.6E-01 6.8E-02]{.underline}

[Thymus 1.3E+00 1.6E-01 8.5E-01 1.1E-01]{.underline}

[Thyroid 8.3E-01 1.1E-01 5.6E-01 6.9E-02]{.underline}

[Urinary Bladder Wall 9.6E-01 1.7E-01 5.8E-01 1.2E-01]{.underline}

[Uterus 1.2E+00 2.2E-01 8.1E-01 1.7E-01]{.underline}

[Effective Dose 4.4E+00 6.7E-01 3.0E+00 5.0E-01]{.underline}

[Equivalent (mSv/MBq)]{.underline}

[Based on model in ICRP 53, using data from patients. Assumed
distribution and retention: ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Liver T]{.underline}~[b]{.underline}~[ = 500 days 42% 5.3% 28%
3.6%]{.underline}

[Kidneys T]{.underline}~[b]{.underline}~[ = 500 days
]{.underline}**[-]{.underline}**[ ]{.underline}**[-]{.underline}**[
0.064% 0.0081%]{.underline}

[Total Body T]{.underline}~[b]{.underline}~[ = 500 days 63% 8.0% 42%
5.3%]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1 day 7% 0.9% 42% 5.3%]{.underline}

`           T`~`b`~` = 1.7 hours    `**`-`**`              `**`-`**`              24%           3.0%`

    Fraction absorbed from SI   70%            8.9%            70%           8.9%

    Urinary bladder receives all output from total body, bladder voiding interval 4.8 hours.

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7) 

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

[ September 18, 1992]{.underline}

[ Radiation Dose Estimates for Co-58 Vitamin B-12
(Cyanocobalamin)]{.underline}

[ Estimated Radiation Dose (mGy/MBq) ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ORGAN Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Adrenals 1.1E+01 1.4E+00 7.3E+00 9.9E-01]{.underline}

[Brain 1.3E+00 1.6E-01 8.3E-01 1.0E-01]{.underline}

[Breasts 2.9E+00 3.8E-01 1.9E+00 2.5E-01]{.underline}

[Gallbladder Wall 2.0E+01 2.7E+00 1.3E+01 1.9E+00]{.underline}

[LLI Wall 3.3E+00 4.0E+00 2.6E+00 3.9E+00]{.underline}

[Small Intestine 4.5E+00 1.4E+00 3.1E+00 1.2E+00]{.underline}

[Stomach 4.9E+00 9.0E-01 3.3E+00 7.1E-01]{.underline}

[ULI Wall 6.2E+00 2.5E+00 4.3E+00 2.2E+00]{.underline}

[Heart Wall 6.6E+00 8.6E-01 4.4E+00 5.8E-01]{.underline}

[Kidneys 7.8E+00 1.1E+00 5.3E+00 8.0E-01]{.underline}

[Liver 5.3E+01 6.8E+00 3.5E+01 4.7E+00]{.underline}

[Lungs 5.6E+00 7.2E-01 3.7E+00 4.9E-01]{.underline}

[Muscle 3.1E+00 5.0E-01 2.1E+00 3.7E-01]{.underline}

[Ovaries 3.1E+00 1.3E+00 2.2E+00 1.2E+00]{.underline}

[Pancreas 9.3E+00 1.3E+00 6.2E+00 9.0E-01]{.underline}

[Red Marrow 3.7E+00 6.4E-01 2.5E+00 4.8E-01]{.underline}

[Bone Surfaces 3.0E+00 4.6E-01 2.0E+00 3.3E-01]{.underline}

[Skin 2.0E+00 3.0E-01 1.4E+00 2.1E-01]{.underline}

[Spleen 3.3E+00 5.1E-01 2.2E+00 3.7E-01]{.underline}

[Testes 1.5E+00 2.9E-01 1.0E+00 2.2E-01]{.underline}

[Thymus 3.0E+00 3.9E-01 2.0E+00 2.6E-01]{.underline}

[Thyroid 1.8E+00 2.3E-01 1.2E+00 1.5E-01]{.underline}

[Urinary Bladder Wall 2.3E+00 5.7E-01 1.6E+00 4.8E-01]{.underline}

[Uterus 2.8E+00 7.6E-01 1.9E+00 6.4E-01]{.underline}

[Effective Dose 8.5E+00 1.6E+00 5.7E+00 1.3E+00]{.underline}

[Equivalent (mSv/MBq)]{.underline}

[Based on model in ICRP 53, using data from patients. Assumed
distribution and retention: ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Liver T]{.underline}~[b]{.underline}~[ = 500 days 42% 5.3% 28%
3.6%]{.underline}

[Kidneys T]{.underline}~[b]{.underline}~[ = 500 days - - 0.064%
0.0081%]{.underline}

[Total Body T]{.underline}~[b]{.underline}~[ = 500 days 63% 8.0% 42%
5.3%]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1 day 7% 0.9% 42% 5.3%]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1.7 hours - - 24% 3.0%]{.underline}

[Fraction absorbed from SI 70% 8.9% 70% 8.9%]{.underline}

    Urinary bladder receives all output from total body, bladder voiding interval 4.8 hours.

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7) 

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	February 26, 1996

[ Radiation Dose Estimates for Fe-59 Citrate \*]{.underline}

[ Estimated Radiation Dose (mGy/MBg)]{.underline}

[ ORGAN Males Females ]{.underline}

[Adrenals 1.0E+01 1.1E+01 ]{.underline}

[Brain 6.7E+00 8.9E+00 ]{.underline}

[Breasts 4.7E+00 6.3E+00 ]{.underline}

[Gallbladder Wall 9.7E+00 9.6E+00 ]{.underline}

[LLI Wall 5.3E+00 7.2E+00 ]{.underline}

[Small Intestine 6.0E+00 7.2E+00 ]{.underline}

[Stomach 8.0E+00 8.9E+00 ]{.underline}

[ULI Wall 6.2E+00 7.7E+00 ]{.underline}

[Heart Wall 1.9E+01 2.4E+01 ]{.underline}

[Kidneys 1.2E+01 1.3E+01 ]{.underline}

[Liver 2.2E+01 1.9E+01 ]{.underline}

[Lungs 1.4E+01 1.9E+01 ]{.underline}

[Muscle 4.9E+00 6.3E+00 ]{.underline}

[Ovaries \-\-\-\-\-\-- 7.3E+00 ]{.underline}

[Pancreas 1.2E+01 1.2E+01 ]{.underline}

[Red Marrow 1.2E+01 1.4E+01 ]{.underline}

[Bone Surfaces 8.5E+00 1.0E+01 ]{.underline}

[Skin 3.4E+00 4.6E+00 ]{.underline}

[Spleen 8.5E+01 5.4E+01 ]{.underline}

[Testes 3.5E+00 \-\-\-\-\-\-- ]{.underline}

[Thymus 6.9E+00 9.0E+00 ]{.underline}

[Thyroid 4.3E+00 5.7E+00 ]{.underline}

[Urinary Bladder Wall 4.5E+00 5.1E+00 ]{.underline}

[Uterus 5.2E+00 6.9E+00 ]{.underline}

[Effective Dose Equivalent 1.4E+01 mSv/MBq 1.4E+01 mSv/MBq]{.underline}

[\*Calculated using the kinetic model of Thind (Health Physics
68(1):9-20, 1995.) Activity in blood apportioned to brain, heart
contents, kidneys, and lungs according to the model of Hui and
Poston.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, in: Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Co-60 Vitamin B-12
(Cyanocobalamin)]{.underline}

[ Estimated Radiation Dose (mGy/MBq) ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ORGAN Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Adrenals 1.7E+02 2.2E+01 1.1E+02 1.5E+01]{.underline}

[Brain 2.0E+01 2.5E+00 1.3E+01 1.6E+00]{.underline}

[Breasts 4.5E+01 5.8E+00 3.0E+01 3.9E+00]{.underline}

[Gallbladder Wall 2.9E+02 3.8E+01 2.0E+02 2.6E+01]{.underline}

[LLI Wall 3.6E+01 1.4E+01 2.5E+01 1.2E+01]{.underline}

[Small Intestine 6.6E+01 1.0E+01 4.4E+01 7.7E+00]{.underline}

[Stomach 7.2E+01 9.8E+00 4.8E+01 6.8E+00]{.underline}

[ULI Wall 9.1E+01 1.6E+01 6.1E+01 1.2E+01]{.underline}

[Heart Wall 1.0E+02 1.3E+01 6.8E+01 8.8E+00]{.underline}

[Kidneys 1.2E+02 1.5E+01 8.0E+01 1.1E+01]{.underline}

[Liver 8.2E+02 1.0E+02 5.5E+02 7.1E+01]{.underline}

[Lungs 8.6E+01 1.1E+01 5.7E+01 7.3E+00]{.underline}

[Muscle 4.8E+01 6.4E+00 3.2E+01 4.3E+00]{.underline}

[Ovaries 4.5E+01 7.9E+00 3.0E+01 5.9E+00]{.underline}

[Pancreas 1.4E+02 1.8E+01 9.2E+01 1.2E+01]{.underline}

[Red Marrow 5.5E+01 7.4E+00 3.7E+01 5.1E+00]{.underline}

[Bone Surfaces 4.6E+01 6.1E+00 3.1E+01 4.1E+00]{.underline}

[Skin 3.3E+01 4.3E+00 2.2E+01 2.9E+00]{.underline}

[Spleen 5.2E+01 6.8E+00 3.5E+01 4.6E+00]{.underline}

[Testes 2.4E+01 3.3E+00 1.6E+01 2.2E+00]{.underline}

[Thymus 4.8E+01 6.1E+00 3.2E+01 4.1E+00]{.underline}

[Thyroid 2.8E+01 3.6E+00 1.9E+01 2.4E+00]{.underline}

[Urinary Bladder Wall 3.5E+01 5.2E+00 2.2E+01 3.4E+00]{.underline}

[Uterus 4.3E+01 6.4E+00 2.9E+01 4.6E+00]{.underline}

[Effective Dose 1.3E+02 1.7E+01 8.7E+01 1.2E+01]{.underline}

[Equivalent (mSv/MBq)]{.underline}

[Based on model in ICRP 53, using data from patients. Assumed
distribution and retention: ]{.underline}

[ No Flushing Dose With Flushing Dose ]{.underline}

[ Normals Pernicious Anemia Normals Pernicious Anemia]{.underline}

[Liver T]{.underline}~[b]{.underline}~[ = 500 days 42% 5.3% 28%
3.6%]{.underline}

[Kidneys T]{.underline}~[b]{.underline}~[ = 500 days - - 0.064%
0.0081%]{.underline}

[Total Body T]{.underline}~[b]{.underline}~[ = 500 days 63% 8.0% 42%
5.3%]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1 day 7% 0.9% 42% 5.3%]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1.7 hours - - 24% 3.0%]{.underline}

    Fraction absorbed from SI   70%            8.9%            70%           8.9%

    Urinary bladder receives all output from total body, bladder voiding interval 4.8 hours.

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7) 

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for Ga-67 Citrate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.3E-01 4.7E-01 ]{.underline}

[Brain 5.4E-02 2.0E-01 ]{.underline}

[Breasts 4.6E-02 1.7E-01 ]{.underline}

[Gallbladder Wall 8.3E-02 3.1E-01 ]{.underline}

[LLI Wall 2.6E-01 9.7E-01 ]{.underline}

[Small Intestine 8.6E-02 3.2E-01 ]{.underline}

[Stomach 6.9E-02 2.6E-01 ]{.underline}

[ULI Wall 1.5E-01 5.4E-01 ]{.underline}

[Heart Wall 6.7E-02 2.5E-01 ]{.underline}

[Kidneys 1.1E-01 4.2E-01 ]{.underline}

[Liver 1.1E-01 4.2E-01 ]{.underline}

[Lungs 6.1E-02 2.3E-01 ]{.underline}

[Muscle 5.9E-02 2.2E-01 ]{.underline}

[Ovaries 8.7E-02 3.2E-01 ]{.underline}

[Pancreas 7.9E-02 2.9E-01 ]{.underline}

[Red Marrow 1.2E-01 4.6E-01 ]{.underline}

[Bone Surfaces 3.2E-01 1.2E+00 ]{.underline}

[Skin 4.4E-02 1.6E-01 ]{.underline}

[Spleen 1.4E-01 5.2E-01 ]{.underline}

[Testes 5.5E-02 2.0E-01 ]{.underline}

[Thymus 5.9E-02 2.2E-01 ]{.underline}

[Thyroid 6.0E-02 2.2E-01 ]{.underline}

[Urinary Bladder Wall 9.0E-02 3.3E-01 ]{.underline}

[Uterus 7.9E-02 2.9E-01 ]{.underline}

[Effective Dose Equivalent 1.1E-01 mSv/MBq 4.1E-01 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 2 (data gathered in
human subjects), J Nucl Med 14:755-756, 1973. Dynamic bladder model with
4.8-hour voiding interval.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	March 18, 1993

[ Radiation Dose Estimates for Ga-68 Citrate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.2E-02 1.2E-01 ]{.underline}

[Brain 1.1E-02 4.2E-02 ]{.underline}

[Breasts 1.1E-02 4.1E-02 ]{.underline}

[Gallbladder Wall 1.7E-02 6.2E-02 ]{.underline}

[LLI Wall 2.1E-02 7.8E-02 ]{.underline}

[Small Intestine 8.8E-02 3.3E-01 ]{.underline}

[Stomach 1.4E-02 5.3E-02 ]{.underline}

[ULI Wall 6.6E-02 2.5E-01 ]{.underline}

[Heart Wall 1.3E-02 4.9E-02 ]{.underline}

[Kidneys 2.7E-02 9.8E-02 ]{.underline}

[Liver 2.7E-02 1.0E-01 ]{.underline}

[Lungs 1.2E-02 4.6E-02 ]{.underline}

[Muscle 1.3E-02 4.7E-02 ]{.underline}

[Ovaries 1.8E-02 6.5E-02 ]{.underline}

[Pancreas 1.5E-02 5.5E-02 ]{.underline}

[Red Marrow 2.1E-02 7.9E-02 ]{.underline}

[Bone Surfaces 1.7E-02 6.3E-02 ]{.underline}

[Skin 1.1E-02 4.0E-02 ]{.underline}

[Spleen 3.6E-02 1.3E-01 ]{.underline}

[Testes 1.2E-02 4.5E-02 ]{.underline}

[Thymus 1.2E-02 4.6E-02 ]{.underline}

[Thyroid 1.2E-02 4.5E-02 ]{.underline}

[Urinary Bladder Wall 2.0E-02 7.4E-02 ]{.underline}

[Uterus 1.7E-02 6.2E-02 ]{.underline}

[Effective Dose Equivalent 2.6E-02 mSv/MBq 9.6E-02 rem/mCi]{.underline}

[Biological model based on MIRD Dose Estimate Report No. 2 (data
gathered in human subjects).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Se‑75 Selenomethionine]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.2E+00 1.2E+01]{.underline}

[Brain 1.4E+00 5.1E+00]{.underline}

[Breasts 1.4E+00 5.1E+00]{.underline}

[Gallbladder Wall 3.8E+00 1.4E+01]{.underline}

[LLI Wall 2.4E+00 8.7E+00]{.underline}

[Small Intestine 2.4E+00 8.9E+00]{.underline}

[Stomach 2.5E+00 9.1E+00]{.underline}

[ULI Wall 2.4E+00 9.0E+00]{.underline}

[Heart Wall 2.6E+00 9.5E+00]{.underline}

[Kidneys 5.2E+00 1.9E+01]{.underline}

[Liver 6.0E+00 2.2E+01]{.underline}

[Lungs 2.7E+00 9.8E+00]{.underline}

[Muscle 2.0E+00 7.3E+00]{.underline}

[Ovaries 2.7E+00 1.0E+01]{.underline}

[Pancreas 3.3E+00 1.2E+01]{.underline}

[Red Marrow 2.1E+00 7.7E+00]{.underline}

[Bone Surfaces 3.0E+00 1.1E+01]{.underline}

[Skin 1.2E+00 4.4E+00]{.underline}

[Spleen 3.7E+00 1.4E+01]{.underline}

[Testes 2.0E+00 7.5E+00]{.underline}

[Thymus 2.0E+00 7.6E+00]{.underline}

[Thyroid 2.6E+00 9.7E+00]{.underline}

[Urinary Bladder Wall 2.1E+00 7.7E+00]{.underline}

[Uterus 2.4E+00 9.0E+00]{.underline}

[Effective Dose Equivalent 2.9E+00 mSv/MBq 1.1E+01 rem/mCi]{.underline}

[Biological model based on MIRD Dose Estimate Report No. 1 (data
gathered in human subjects).]{.underline}

[Dynamic bladder model with a 4.8 hour voiding interval:]{.underline}

[ 11.20% Tb = 1.33E+01 hr.]{.underline}

[ 35.20% Tb = 1.10E+03 hr.]{.underline}

[ 33.60% Tb = 5.33E+03 hr.]{.underline}

[ICRP 30 GI model used, 15% to the small intestine]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Kr‑81m Inhalation]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.3E-06 1.6E-05]{.underline}

[Brain 1.7E-07 6.1E-07]{.underline}

[Breasts 4.3E-06 1.6E-05]{.underline}

[Gallbladder Wall 1.4E-06 5.1E-06]{.underline}

[LLI Wall 7.4E-08 2.7E-07]{.underline}

[Small Intestine 2.7E-07 1.0E-06]{.underline}

[Stomach 2.1E-06 7.9E-06]{.underline}

[ULI Wall 3.6E-07 1.3E-06]{.underline}

[Heart Wall 7.8E-06 2.9E-05]{.underline}

[Kidneys 1.2E-06 4.6E-06]{.underline}

[Liver 3.6E-06 1.3E-05]{.underline}

[Lungs 2.0E-04 7.4E-04]{.underline}

[Muscle 1.7E-06 6.4E-06]{.underline}

[Ovaries 1.3E-07 5.0E-07]{.underline}

[Pancreas 3.0E-06 1.1E-05]{.underline}

[Red Marrow 2.1E-06 7.7E-06]{.underline}

[Bone Surfaces 2.3E-06 8.5E-06]{.underline}

[Skin 7.6E-07 2.8E-06]{.underline}

[Spleen 3.0E-06 1.1E-05]{.underline}

[Testes 1.0E-08 3.8E-08]{.underline}

[Thymus 5.0E-06 1.9E-05]{.underline}

[Thyroid 1.6E-06 5.9E-06]{.underline}

[Urinary Bladder Wall 3.6E-08 1.3E-07]{.underline}

[Uterus 9.9E-08 3.7E-07]{.underline}

[Effective Dose Equivalent 2.7E-05 mSv/MBq 9.8E-05 rem/mCi]{.underline}

[Assumes that all activity inhaled decays in lungs (no patient or animal
data used).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Kr‑81m Injections]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.5E-06 1.7E-05]{.underline}

[Brain 9.7E-08 3.6E-07]{.underline}

[Breasts 4.5E-06 1.7E-05]{.underline}

[Gallbladder Wall 1.7E-06 6.4E-06]{.underline}

[LLI Wall 8.9E-08 3.3E-07]{.underline}

[Small Intestine 3.0E-07 1.1E-06]{.underline}

[Stomach 2.8E-06 1.0E-05]{.underline}

[ULI Wall 4.3E-07 1.6E-06]{.underline}

[Heart Wall 1.9E-04 7.1E-04]{.underline}

[Kidneys 1.2E-06 4.4E-06]{.underline}

[Liver 3.8E-06 1.4E-05]{.underline}

[Lungs 5.1E-05 1.9E-04]{.underline}

[Muscle 1.6E-06 6.0E-06]{.underline}

[Ovaries 1.2E-07 4.4E-07]{.underline}

[Pancreas 4.3E-06 1.6E-05]{.underline}

[Red Marrow 2.1E-06 7.6E-06]{.underline}

[Bone Surfaces 2.2E-06 8.3E-06]{.underline}

[Skin 6.7E-07 2.5E-06]{.underline}

[Spleen 2.4E-06 8.7E-06]{.underline}

[Testes 1.4E-08 5.2E-08]{.underline}

[Thymus 1.3E-05 5.0E-05]{.underline}

[Thyroid 1.1E-06 4.0E-06]{.underline}

[Urinary Bladder Wall 5.1E-08 1.9E-07]{.underline}

[Uterus 1.1E-07 4.2E-07]{.underline}

[Effective Dose Equivalent 2.0E-05 mSv/MBq 7.5E-05 rem/mCi]{.underline}

[Residence times based on a model in which activity clears from the
blood,]{.underline}

[to the right heart, lungs, left heart, and back to blood, with 95%
clearance]{.underline}

[of blood from lungs on each pass. Half times for transport are 1 minute
in]{.underline}

[heart chambers, 5 minutes in lung, and 3 minutes in the body. (No
patient or animal data used).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Oral Administration of
Kr‑81m]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.0E-06 1.9E-05]{.underline}

[Brain 1.5E-08 5.4E-08]{.underline}

[Breasts 1.1E-06 4.0E-06]{.underline}

[Gallbladder Wall 5.4E-06 2.0E-05]{.underline}

[LLI Wall 1.6E-06 5.8E-06]{.underline}

[Small Intestine 3.7E-06 1.4E-05]{.underline}

[Stomach 4.1E-04 1.5E-03]{.underline}

[ULI Wall 4.7E-06 1.7E-05]{.underline}

[Heart Wall 4.3E-06 1.6E-05]{.underline}

[Kidneys 5.0E-06 1.9E-05]{.underline}

[Liver 2.7E-06 9.9E-06]{.underline}

[Lungs 1.9E-06 7.2E-06]{.underline}

[Muscle 1.8E-06 6.7E-06]{.underline}

[Ovaries 1.1E-06 4.0E-06]{.underline}

[Pancreas 2.2E-05 8.2E-05]{.underline}

[Red Marrow 1.5E-06 5.4E-06]{.underline}

[Bone Surfaces 1.5E-06 5.4E-06]{.underline}

[Skin 6.5E-07 2.4E-06]{.underline}

[Spleen 1.4E-05 5.2E-05]{.underline}

[Testes 7.6E-08 2.8E-07]{.underline}

[Thymus 7.5E-07 2.8E-06]{.underline}

[Thyroid 6.6E-08 2.4E-07]{.underline}

[Urinary Bladder Wall 3.7E-07 1.4E-06]{.underline}

[Uterus 9.3E-07 3.4E-06]{.underline}

[Effective Dose Equivalent 2.8E-05 mSv/MBq 1.1E-04 rem/mCi]{.underline}

[All activity administered assumed to decay in stomach (no patient or
animal data used).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Rb-82]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.4E-04 1.6E-03]{.underline}

[Brain 3.2E-04 1.2E-03]{.underline}

[Breasts 3.3E-04 1.2E-03]{.underline}

[Gallbladder Wall 4.2E-04 1.5E-03]{.underline}

[LLI Wall 3.6E-04 1.3E-03]{.underline}

[Small Intestine 3.8E-04 1.4E-03]{.underline}

[Stomach 3.8E-04 1.4E-03]{.underline}

[ULI Wall 3.8E-04 1.4E-03]{.underline}

[Heart Wall 1.8E-03 6.7E-03]{.underline}

[Kidneys 9.0E-03 3.3E-02]{.underline}

[Liver 8.3E-04 3.1E-03]{.underline}

[Lungs 1.7E-03 6.4E-03]{.underline}

[Muscle 3.5E-04 1.3E-03]{.underline}

[Ovaries 3.7E-04 1.4E-03]{.underline}

[Pancreas 4.2E-04 1.6E-03]{.underline}

[Red Marrow 4.5E-04 1.7E-03]{.underline}

[Bone Surfaces 3.3E-04 1.2E-03]{.underline}

[Skin 3.2E-04 1.2E-03]{.underline}

[Spleen 4.1E-04 1.5E-03]{.underline}

[Testes 2.6E-04 9.5E-04]{.underline}

[Thymus 3.7E-04 1.4E-03]{.underline}

[Thyroid 3.4E-04 1.3E-03]{.underline}

[Urinary Bladder Wall 3.6E-04 1.3E-03]{.underline}

[Uterus 3.7E-04 1.4E-03]{.underline}

[Effective Dose Equivalent 1.2E-03 mSv/MBq 4.3E-03 rem/mCi]{.underline}

[Based on data gathered in human subjects by Ryan et al., Fourth
International Radiopharmaceutical Dosimetry Symposium, Oak Ridge, 1985,
pp. 346-358. Assumed residence times:]{.underline}

[ Heart Chambers 5.25 x 10]{.underline}^[-4]{.underline}^

[ Heart Wall 4.95 x 10]{.underline}^[-4]{.underline}^

[ Kidneys 3.11 x 10]{.underline}^[-3]{.underline}^

[ Liver 1.54 x 10]{.underline}^[-3]{.underline}^

[ Lungs 1.95 x 10]{.underline}^[-3]{.underline}^

[ Testes 9.00 x 10]{.underline}^[-6]{.underline}^

[ Remainder 2.24 x 10]{.underline}^[-2]{.underline}^

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for Sr-85 Nitrate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 9.0E-01 3.3E+00 ]{.underline}

[Brain 8.8E-01 3.2E+00 ]{.underline}

[Breasts 4.0E-01 1.5E+00 ]{.underline}

[Gallbladder Wall 6.0E-01 2.2E+00 ]{.underline}

[LLI Wall 9.8E-01 3.6E+00 ]{.underline}

[Small Intestine 6.8E-01 2.5E+00 ]{.underline}

[Stomach 5.5E-01 2.0E+00 ]{.underline}

[ULI Wall 6.9E-01 2.5E+00 ]{.underline}

[Heart Wall 6.2E-01 2.3E+00 ]{.underline}

[Kidneys 6.5E-01 2.4E+00 ]{.underline}

[Liver 5.8E-01 2.1E+00 ]{.underline}

[Lungs 6.3E-01 2.3E+00 ]{.underline}

[Muscle 6.7E-01 2.5E+00 ]{.underline}

[Ovaries 7.5E-01 2.8E+00 ]{.underline}

[Pancreas 7.0E-01 2.6E+00 ]{.underline}

[Red Marrow 1.4E+00 5.3E+00 ]{.underline}

[Bone Surfaces 2.0E+00 7.6E+00 ]{.underline}

[Skin 4.9E-01 1.8E+00 ]{.underline}

[Spleen 5.8E-01 2.1E+00 ]{.underline}

[Testes 5.0E-01 1.9E+00 ]{.underline}

[Thymus 5.5E-01 2.0E+00 ]{.underline}

[Thyroid 7.0E-01 2.6E+00 ]{.underline}

[Urinary Bladder Wall 6.3E-01 2.3E+00 ]{.underline}

[Uterus 6.5E-01 2.4E+00 ]{.underline}

[Effective Dose Equivalent 8.3E-01 mSv/MBq 3.1E+00 rem/mCi]{.underline}

[Biological model based on ICRP 53 (data gathered in human
subjects).]{.underline}

[Cortical bone τ = 201.6 hour Cancellous bone τ = 160.8
hour]{.underline}

[Small Intestine τ = 0.6 hour Upper Large Intestine τ = 2.0
hour]{.underline}

[Lower Large Intestine τ = 3.6 hour Urinary bladder τ = 1.1
hour]{.underline}

[Remainder of body τ = 163.1 hour]{.underline}

[Dynamic bladder model with 3.5-hour voiding interval]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Tc‑99m Albumin Microspheres]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 7.3E-03 2.7E-02]{.underline}

[Brain 1.2E-03 4.5E-03]{.underline}

[Breasts 4.6E-03 1.7E-02]{.underline}

[Gallbladder Wall 4.7E-03 1.8E-02]{.underline}

[LLI Wall 7.8E-03 2.9E-02]{.underline}

[Small Intestine 3.9E-03 1.5E-02]{.underline}

[Stomach 1.8E-02 6.5E-02]{.underline}

[ULI Wall 9.0E-03 3.3E-02]{.underline}

[Heart Wall 8.7E-03 3.2E-02]{.underline}

[Kidneys 3.6E-02 1.3E-01]{.underline}

[Liver 5.5E-03 2.0E-02]{.underline}

[Lungs 5.8E-02 2.2E-01]{.underline}

[Muscle 3.2E-03 1.2E-02]{.underline}

[Ovaries 3.4E-03 1.3E-02]{.underline}

[Pancreas 7.5E-03 2.8E-02]{.underline}

[Red Marrow 3.8E-03 1.4E-02]{.underline}

[Bone Surfaces 5.6E-03 2.1E-02]{.underline}

[Skin 1.6E-03 6.1E-03]{.underline}

[Spleen 6.8E-03 2.5E-02]{.underline}

[Testes 1.5E-03 5.6E-03]{.underline}

[Thymus 5.8E-03 2.1E-02]{.underline}

[Thyroid 1.4E-02 5.0E-02]{.underline}

[Urinary Bladder Wall 1.0E-02 3.8E-02]{.underline}

[Uterus 3.3E-03 1.2E-02]{.underline}

[Effective Dose Equivalent 1.4E-02 mSv/MBq 5.4E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 10 (data gathered in
human subjects), J Nucl Med 23:915-917, 1982.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m for the Adult]{.underline}

[ for Disofenin, Lidofenin and Mebrofenin]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.6E-03 1.3E-02]{.underline}

[Brain 6.9E-05 2.6E-04]{.underline}

[Breasts 4.7E-04 1.7E-03]{.underline}

[Gallbladder Wall 1.1E-01 4.0E-01]{.underline}

[LLI Wall 6.0E-02 2.2E-01]{.underline}

[Small Intestine 4.4E-02 1.6E-01]{.underline}

[Stomach 5.6E-03 2.1E-02]{.underline}

[ULI Wall 8.6E-02 3.2E-01]{.underline}

[Heart Wall 1.4E-03 5.4E-03]{.underline}

[Kidneys 6.0E-03 2.2E-02]{.underline}

[Liver 1.4E-02 5.2E-02]{.underline}

[Lungs 1.1E-03 4.2E-03]{.underline}

[Muscle 3.0E-03 1.1E-02]{.underline}

[Ovaries 1.9E-02 7.1E-02]{.underline}

[Pancreas 5.6E-03 2.1E-02]{.underline}

[Red Marrow 3.9E-03 1.5E-02]{.underline}

[Bone Surfaces 3.8E-03 1.4E-02]{.underline}

[Skin 9.2E-04 3.4E-03]{.underline}

[Spleen 2.5E-03 9.3E-03]{.underline}

[Testes 1.7E-03 6.3E-03]{.underline}

[Thymus 3.7E-04 1.4E-03]{.underline}

[Thyroid 1.2E-04 4.5E-04]{.underline}

[Urinary Bladder Wall 2.7E-02 9.9E-02]{.underline}

[Uterus 1.4E-02 5.1E-02]{.underline}

[Effective Dose Equivalent 2.5E-02 mSv/MBq 9.3E-02 rem/mCi]{.underline}

[Biological model based on ICRP 53 (data gathered in human
subjects).]{.underline}

[Kidneys τ = 0.012 hour Gallbladder contents τ = 0.77 hour]{.underline}

[Liver τ = 0.80 hour Small Intestine τ = 1.79 hour]{.underline}

[Upper Large Intestine τ = 2.34 hour Lower Large Intestine τ = 1.14
hour]{.underline}

[Urinary bladder τ = 0.53 hour Remainder of body τ = 0.14
hour]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

[ September 18, 1992]{.underline}

[ Radiation Dose Estimates for Tc‑99m DMSA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.2E-02 4.3E-02]{.underline}

[Brain 1.3E-03 4.9E-03]{.underline}

[Breasts 1.4E-03 5.0E-03]{.underline}

[Gallbladder Wall 7.5E-03 2.8E-02]{.underline}

[LLI Wall 3.3E-03 1.2E-02]{.underline}

[Small Intestine 5.0E-03 1.9E-02]{.underline}

[Stomach 5.2E-03 1.9E-02]{.underline}

[ULI Wall 4.9E-03 1.8E-02]{.underline}

[Heart Wall 2.9E-03 1.1E-02]{.underline}

[Kidneys 1.9E-01 7.0E-01]{.underline}

[Liver 5.7E-03 2.1E-02]{.underline}

[Lungs 2.4E-03 9.0E-03]{.underline}

[Muscle 2.9E-03 1.1E-02]{.underline}

[Ovaries 3.5E-03 1.3E-02]{.underline}

[Pancreas 8.7E-03 3.2E-02]{.underline}

[Red Marrow 4.1E-03 1.5E-02]{.underline}

[Bone Surfaces 5.0E-03 1.9E-02]{.underline}

[Skin 1.6E-03 5.8E-03]{.underline}

[Spleen 1.1E-02 4.0E-02]{.underline}

[Testes 1.8E-03 6.8E-03]{.underline}

[Thymus 1.8E-03 6.6E-03]{.underline}

[Thyroid 1.6E-03 6.0E-03]{.underline}

[Urinary Bladder Wall 1.5E-02 5.4E-02]{.underline}

[Uterus 4.2E-03 1.6E-02]{.underline}

[Effective Dose Equivalent 1.6E-02 mSv/MBq 6.0E-02 rem/mCi]{.underline}

[Based on data gathered in human subjects by Arnold et al., J Nucl Med
16:357-367, 1975. Assumed distribution and retention:]{.underline}

[ Total body 80% T]{.underline}~[b]{.underline}~[ = 72 hr 20%
T]{.underline}~[b]{.underline}~[ = 1.6 hr]{.underline}

[ Kidneys 44% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Urinary bladder receives whole body clearance: 44.8%,
T]{.underline}~[b]{.underline}~[ = 72 hr, 11.2%,]{.underline}

[ T]{.underline}~[b]{.underline}~[ = 1.6 hr. Bladder voiding interval
4.8 hours.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Tc‑99m DTPA (injection) ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.0E-03 7.4E-03]{.underline}

[Brain 1.3E-03 4.7E-03]{.underline}

[Breasts 1.1E-03 4.0E-03]{.underline}

[Gallbladder Wall 2.2E-03 8.1E-03]{.underline}

[LLI Wall 5.6E-03 2.1E-02]{.underline}

[Small Intestine 3.4E-03 1.3E-02]{.underline}

[Stomach 1.9E-03 6.9E-03]{.underline}

[ULI Wall 2.9E-03 1.1E-02]{.underline}

[Heart Wall 1.7E-03 6.3E-03]{.underline}

[Kidneys 5.7E-03 2.1E-02]{.underline}

[Liver 1.8E-03 6.6E-03]{.underline}

[Lungs 1.5E-03 5.5E-03]{.underline}

[Muscle 2.2E-03 8.3E-03]{.underline}

[Ovaries 5.5E-03 2.0E-02]{.underline}

[Pancreas 2.1E-03 7.7E-03]{.underline}

[Red Marrow 2.2E-03 8.0E-03]{.underline}

[Bone Surfaces 3.3E-03 1.2E-02]{.underline}

[Skin 1.2E-03 4.6E-03]{.underline}

[Spleen 1.9E-03 6.8E-03]{.underline}

[Testes 3.8E-03 1.4E-02]{.underline}

[Thymus 1.5E-03 5.6E-03]{.underline}

[Thyroid 1.5E-03 5.6E-03]{.underline}

[Urinary Bladder Wall 7.7E-02 2.8E-01]{.underline}

[Uterus 1.0E-02 3.7E-02]{.underline}

[Effective Dose Equivalent 8.2E-03 mSv/MBq 3.0E-02 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 12 (data gathered
in human subjects), J Nucl Med 25:503-505, 1984.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

            Information Center

                           	September 18, 1992

[ Radiation Dose Estimates for Tc‑99m DTPA (aerosol) ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.9E-03 7.2E-03]{.underline}

[Brain 6.8E-04 2.5E-03]{.underline}

[Breasts 1.4E-03 5.2E-03]{.underline}

[Gallbladder Wall 1.8E-03 6.7E-03]{.underline}

[LLI Wall 5.2E-03 1.9E-02]{.underline}

[Small Intestine 3.5E-03 1.3E-02]{.underline}

[Stomach 2.4E-03 9.0E-03]{.underline}

[ULI Wall 5.3E-03 2.0E-02]{.underline}

[Heart Wall 2.5E-03 9.3E-03]{.underline}

[Kidneys 3.0E-03 1.1E-02]{.underline}

[Liver 1.7E-03 6.4E-03]{.underline}

[Lungs 1.4E-02 5.3E-02]{.underline}

[Muscle 1.5E-03 5.6E-03]{.underline}

[Ovaries 3.3E-03 1.2E-02]{.underline}

[Pancreas 1.9E-03 7.1E-03]{.underline}

[Red Marrow 1.6E-03 5.9E-03]{.underline}

[Bone Surfaces 2.4E-03 8.7E-03]{.underline}

[Skin 7.8E-04 2.9E-03]{.underline}

[Spleen 1.7E-03 6.2E-03]{.underline}

[Testes 1.7E-03 6.4E-03]{.underline}

[Thymus 1.8E-03 6.7E-03]{.underline}

[Thyroid 1.1E-03 4.1E-03]{.underline}

[Urinary Bladder Wall 3.2E-02 1.2E-01]{.underline}

[Uterus 4.8E-03 1.8E-02]{.underline}

[Effective Dose Equivalent 6.1E-03 mSv/MBq 2.2E-02 rem/mCi]{.underline}

[Dose estimates are given per unit activity inhaled, based on an assumed
0.25 μm AMAD aerosol. Deposition fractions and kinetics based on lung
model in ICRP 30, except that activity is cleared from the pulmonary
region into the bloodstream with a one hour biological half time. DTPA
absorbed into the bloodstream treated as in MIRD Dose Estimate No. 12
(data gathered in human subjects), J Nucl Med 25:503-505, 1984. Urinary
bladder voiding interval 4.8 hours.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 12, 1995

[ Radiation Dose Estimates for Tc-99m ECD\*]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.5E-03 9.3E-03 ]{.underline}

[Brain 5.5E-03 2.0E-02 ]{.underline}

[Breasts 9.4E-04 3.5E-03 ]{.underline}

[Gallbladder Wall 2.7E-02 1.0E-01 ]{.underline}

[LLI Wall 1.5E-02 5.4E-02 ]{.underline}

[Small Intestine 1.0E-02 3.7E-02 ]{.underline}

[Stomach 2.5E-03 9.3E-03 ]{.underline}

[ULI Wall 1.7E-02 6.2E-02 ]{.underline}

[Heart Wall 1.8E-03 6.5E-03 ]{.underline}

[Kidneys 7.7E-03 2.9E-02 ]{.underline}

[Liver 5.4E-03 2.0E-02 ]{.underline}

[Lungs 2.0E-03 7.4E-03 ]{.underline}

[Muscle 2.4E-03 8.8E-03 ]{.underline}

[Ovaries 7.8E-03 2.9E-02 ]{.underline}

[Pancreas 2.9E-03 1.1E-02 ]{.underline}

[Red Marrow 2.4E-03 9.0E-03 ]{.underline}

[Bone Surfaces 3.7E-03 1.4E-02 ]{.underline}

[Skin 1.2E-03 4.3E-03 ]{.underline}

[Spleen 2.0E-03 7.3E-03 ]{.underline}

[Testes 3.5E-03 1.3E-02 ]{.underline}

[Thymus 1.2E-03 4.6E-03 ]{.underline}

[Thyroid 1.3E-03 4.8E-03 ]{.underline}

[Urinary Bladder Wall 7.3E-02 2.7E-01 ]{.underline}

[Uterus 1.1E-02 4.1E-02 ]{.underline}

[Total Body 2.7E-03 1.0E-02 ]{.underline}

[Effective Dose Equivalent 1.1E-02 mSv/MBq 4.2E-02 rem/mCi]{.underline}

[\*Based on data gathered in 16 patients. Assumed distribution and
retention:]{.underline}

[Brain 4.6% T]{.underline}~[b]{.underline}~[ = 22.4 hr 2.1%
T]{.underline}~[b]{.underline}~[ = 0.554 hr]{.underline}

[Heart Wall 0.43% T]{.underline}~[b]{.underline}~[ = 1.9 hr 0.32%
T]{.underline}~[b]{.underline}~[ = 0.31 hr]{.underline}

[Kidneys 1.2% T]{.underline}~[b]{.underline}~[ = 14.4 hr 7.8%
T]{.underline}~[b]{.underline}~[ = 0.4 hr]{.underline}

[Liver 3.5% T]{.underline}~[b]{.underline}~[ = 18.6 hr 15.5%
T]{.underline}~[b]{.underline}~[ = 0.42 hr]{.underline}

[Lungs 0.97% T]{.underline}~[b]{.underline}~[ = 12.0 hr 4.7%
T]{.underline}~[b]{.underline}~[ = 0.25 hr]{.underline}

[Gallbladder: average residence time 0.185 hr]{.underline}

[Total Body 30.6% T]{.underline}~[b]{.underline}~[ = 31.2 hr 69.4%
T]{.underline}~[b]{.underline}~[ = 0.854 hr]{.underline}

[Urinary Bladder 19% T]{.underline}~[b]{.underline}~[ = 68.5 hr 70%
T]{.underline}~[b]{.underline}~[ = 1.11 hr]{.underline}

[GI Tract: 11% of total activity cleared into small intestine,
follows]{.underline}

    GI tract kinetics as in ICRP 30.

[Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/
TM - 8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke-Stelson and E.E. Watson eds. CONF
-851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986.
Pp 514-534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m Exametazime (HMPAO)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.9E-03 2.2E-02]{.underline}

[Brain 6.9E-03 2.5E-02]{.underline}

[Breasts 1.9E-03 7.0E-03]{.underline}

[Gallbladder Wall 5.1E-02 1.9E-01]{.underline}

[LLI Wall 1.5E-02 5.7E-02]{.underline}

[Small Intestine 1.2E-02 4.6E-02]{.underline}

[Stomach 4.2E-03 1.5E-02]{.underline}

[ULI Wall 2.2E-02 8.0E-02]{.underline}

[Heart Wall 3.8E-03 1.4E-02]{.underline}

[Kidneys 3.5E-02 1.3E-01]{.underline}

[Liver 1.5E-02 5.4E-02]{.underline}

[Lungs 1.1E-02 4.2E-02]{.underline}

[Muscle 2.9E-03 1.1E-02]{.underline}

[Ovaries 7.0E-03 2.6E-02]{.underline}

[Pancreas 5.9E-03 2.2E-02]{.underline}

[Red Marrow 3.5E-03 1.3E-02]{.underline}

[Bone Surfaces 4.9E-03 1.8E-02]{.underline}

[Skin 1.5E-03 5.6E-03]{.underline}

[Spleen 4.2E-03 1.5E-02]{.underline}

[Testes 2.3E-03 8.4E-03]{.underline}

[Thymus 2.4E-03 8.8E-03]{.underline}

[Thyroid 2.7E-02 1.0E-01]{.underline}

[Urinary Bladder Wall 2.8E-02 1.0E-01]{.underline}

[Uterus 7.1E-03 2.6E-02]{.underline}

[Effective Dose Equivalent 1.4E-02 mSv/MBq 5.1E-02 rem/mCi]{.underline}

[Based on data gathered in patients (see Nucl Med Comm 11:791-799, 1990.
Assumed distribution and retention:]{.underline}

[Brain 5.1 % T]{.underline}~[b]{.underline}~[ = 92.4 hours]{.underline}

[Gallbladder 4.0 % T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Kidneys 9.0 % T]{.underline}~[b]{.underline}~[ = 27.7
hours]{.underline}

[Liver 10.4 % T]{.underline}~[b]{.underline}~[ = 116 hours 11.6 %
T]{.underline}~[b]{.underline}~[ = 0.73 hours]{.underline}

[Lungs 8.6 % T]{.underline}~[b]{.underline}~[ = 69 hours 1.4 %
T]{.underline}~[b]{.underline}~[ = 1.6 hours]{.underline}

[Thyroid 0.54 % T]{.underline}~[b]{.underline}~[ = 54.1 hours 0.26 %
T]{.underline}~[b]{.underline}~[ = 1.07 hours]{.underline}

[Remainder of]{.underline}

[ the body 29.4 % T]{.underline}~[b]{.underline}~[ = 43.3 hours 16.6 %
T]{.underline}~[b]{.underline}~[ = 0.93 hours]{.underline}

     Dynamic Bladder Model used (4.80 hour void)

          24.0 %     Tb =  8.30 hours

          13.0 %     Tb =  0.55 hours

     ICRP 30 GI Model used, with 14.0 % to the small intestine

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m Glucoheptonate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.1E-03 1.5E-02]{.underline}

[Brain 1.2E-03 4.6E-03]{.underline}

[Breasts 1.1E-03 4.1E-03]{.underline}

[Gallbladder Wall 3.4E-03 1.3E-02]{.underline}

[LLI Wall 5.6E-03 2.1E-02]{.underline}

[Small Intestine 3.9E-03 1.4E-02]{.underline}

[Stomach 2.5E-03 9.4E-03]{.underline}

[ULI Wall 3.4E-03 1.3E-02]{.underline}

[Heart Wall 1.9E-03 7.1E-03]{.underline}

[Kidneys 4.4E-02 1.6E-01]{.underline}

[Liver 3.2E-03 1.2E-02]{.underline}

[Lungs 1.7E-03 6.2E-03]{.underline}

[Muscle 2.5E-03 9.1E-03]{.underline}

[Ovaries 5.5E-03 2.0E-02]{.underline}

[Pancreas 3.5E-03 1.3E-02]{.underline}

[Red Marrow 2.6E-03 9.5E-03]{.underline}

[Bone Surfaces 3.7E-03 1.4E-02]{.underline}

[Skin 1.3E-03 4.8E-03]{.underline}

[Spleen 3.7E-03 1.4E-02]{.underline}

[Testes 3.7E-03 1.4E-02]{.underline}

[Thymus 1.5E-03 5.6E-03]{.underline}

[Thyroid 1.5E-03 5.5E-03]{.underline}

[Urinary Bladder Wall 7.4E-02 2.7E-01]{.underline}

[Uterus 9.9E-03 3.6E-02]{.underline}

[Effective Dose Equivalent 1.0E-02 mSv/MBq 3.8E-02 rem/mCi]{.underline}

[Based on data gathered in humans by Arnold et al., J Nucl Med
16:357-367, 1975. Assumed distribution and retention:]{.underline}

[ Kidneys 14.6% uptake T]{.underline}~[b]{.underline}~[ = 0.75 hr
elimination T]{.underline}~[b]{.underline}~[ = 24 hr]{.underline}

[ Liver 1.5% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Total Body 35% T]{.underline}~[b]{.underline}~[ = 89 hr 30%
T]{.underline}~[b]{.underline}~[ = 2.04 hr 35%
T]{.underline}~[b]{.underline}~[ = 0.333 hr]{.underline}

[ All clearance through urinary bladder, 4.8 hour bladder voiding
interval.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Tc-99m HEDP ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.4E-03 8.8E-03 ]{.underline}

[Brain 1.6E-03 6.0E-03 ]{.underline}

[Breasts 1.0E-03 3.8E-03 ]{.underline}

[Gallbladder Wall 2.1E-03 7.7E-03 ]{.underline}

[LLI Wall 3.8E-03 1.4E-02 ]{.underline}

[Small Intestine 2.7E-03 1.0E-02 ]{.underline}

[Stomach 1.8E-03 6.5E-03 ]{.underline}

[ULI Wall 2.4E-03 8.8E-03 ]{.underline}

[Heart Wall 1.7E-03 6.4E-03 ]{.underline}

[Kidneys 9.3E-03 3.5E-02 ]{.underline}

[Liver 1.8E-03 6.6E-03 ]{.underline}

[Lungs 1.6E-03 5.8E-03 ]{.underline}

[Muscle 2.0E-03 7.4E-03 ]{.underline}

[Ovaries 3.8E-03 1.4E-02 ]{.underline}

[Pancreas 2.2E-03 8.1E-03 ]{.underline}

[Red Marrow 3.7E-03 1.4E-02 ]{.underline}

[Bone Surfaces 1.9E-02 7.1E-02 ]{.underline}

[Skin 1.2E-03 4.4E-03 ]{.underline}

[Spleen 2.0E-03 7.3E-03 ]{.underline}

[Testes 2.6E-03 9.6E-03 ]{.underline}

[Thymus 1.5E-03 5.5E-03 ]{.underline}

[Thyroid 1.6E-03 6.0E-03 ]{.underline}

[Urinary Bladder Wall 4.1E-02 1.5E-01 ]{.underline}

[Uterus 6.1E-03 2.2E-02 ]{.underline}

[Effective Dose Equivalent 6.1E-03 mSv/MBq 2.3E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 13 (data gathered in
human subjects), J Nucl Med 30:1117-1122, 1989. Bladder voiding interval
4.8 hr.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Tc-99m HMDP ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.1E-03 1.2E-02 ]{.underline}

[Brain 2.7E-03 9.8E-03 ]{.underline}

[Breasts 1.3E-03 4.8E-03 ]{.underline}

[Gallbladder Wall 2.3E-03 8.4E-03 ]{.underline}

[LLI Wall 3.5E-03 1.3E-02 ]{.underline}

[Small Intestine 2.7E-03 1.0E-02 ]{.underline}

[Stomach 2.0E-03 7.3E-03 ]{.underline}

[ULI Wall 2.5E-03 9.1E-03 ]{.underline}

[Heart Wall 2.2E-03 8.1E-03 ]{.underline}

[Kidneys 6.0E-03 2.2E-02 ]{.underline}

[Liver 2.1E-03 7.7E-03 ]{.underline}

[Lungs 2.1E-03 7.9E-03 ]{.underline}

[Muscle 2.4E-03 8.8E-03 ]{.underline}

[Ovaries 3.4E-03 1.3E-02 ]{.underline}

[Pancreas 2.6E-03 9.5E-03 ]{.underline}

[Red Marrow 7.5E-03 2.8E-02 ]{.underline}

[Bone Surfaces 5.2E-02 1.9E-01 ]{.underline}

[Skin 1.5E-03 5.6E-03 ]{.underline}

[Spleen 2.2E-03 8.1E-03 ]{.underline}

[Testes 2.3E-03 8.5E-03 ]{.underline}

[Thymus 1.9E-03 7.0E-03 ]{.underline}

[Thyroid 2.3E-03 8.5E-03 ]{.underline}

[Urinary Bladder Wall 2.2E-02 8.0E-02 ]{.underline}

[Uterus 4.4E-03 1.6E-02 ]{.underline}

[Effective Dose Equivalent 6.1E-03 mSv/MBq 2.3E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 13 (data gathered in
human subjects), J Nucl Med 30:1117-1122, 1989. Bladder voiding interval
4.8 hr.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m HSA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 6.0E-03 2.2E-02]{.underline}

[Brain 7.5E-03 2.8E-02]{.underline}

[Breasts 3.7E-03 1.4E-02]{.underline}

[Gallbladder Wall 5.5E-03 2.1E-02]{.underline}

[LLI Wall 4.0E-03 1.5E-02]{.underline}

[Small Intestine 4.3E-03 1.6E-02]{.underline}

[Stomach 4.9E-03 1.8E-02]{.underline}

[ULI Wall 4.3E-03 1.6E-02]{.underline}

[Heart Wall 2.1E-02 7.7E-02]{.underline}

[Kidneys 8.6E-03 3.2E-02]{.underline}

[Liver 8.2E-03 3.0E-02]{.underline}

[Lungs 1.5E-02 5.6E-02]{.underline}

[Muscle 3.6E-03 1.3E-02]{.underline}

[Ovaries 4.2E-03 1.6E-02]{.underline}

[Pancreas 6.3E-03 2.3E-02]{.underline}

[Red Marrow 4.3E-03 1.6E-02]{.underline}

[Bone Surfaces 7.0E-03 2.6E-02]{.underline}

[Skin 2.4E-03 8.8E-03]{.underline}

[Spleen 1.5E-02 5.7E-02]{.underline}

[Testes 2.9E-03 1.1E-02]{.underline}

[Thymus 6.5E-03 2.4E-02]{.underline}

[Thyroid 3.8E-03 1.4E-02]{.underline}

[Urinary Bladder Wall 5.3E-03 2.0E-02]{.underline}

[Uterus 4.3E-03 1.6E-02]{.underline}

[Effective Dose Equivalent 7.9E-03 mSv/MBq 2.9E-02 rem/mCi]{.underline}

[Based on total body kinetic model in ICRP 53 (data gathered in human
subjects), modified by the assumed fractional distribution of blood in
model by Hui and Poston.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

[ September 18, 1992]{.underline}

[ Radiation Dose Estimates for Tc-99m MAA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 6.7E-03 2.5E-02]{.underline}

[Brain 9.2E-04 3.4E-03]{.underline}

[Breasts 5.0E-03 1.8E-02]{.underline}

[Gallbladder Wall 5.6E-03 2.1E-02]{.underline}

[LLI Wall 1.7E-03 6.1E-03]{.underline}

[Small Intestine 2.0E-03 7.3E-03]{.underline}

[Stomach 3.7E-03 1.4E-02]{.underline}

[ULI Wall 2.2E-03 8.2E-03]{.underline}

[Heart Wall 9.5E-03 3.5E-02]{.underline}

[Kidneys 3.7E-03 1.4E-02]{.underline}

[Liver 1.6E-02 5.9E-02]{.underline}

[Lungs 6.7E-02 2.5E-01]{.underline}

[Muscle 2.8E-03 1.1E-02]{.underline}

[Ovaries 1.8E-03 6.7E-03]{.underline}

[Pancreas 5.6E-03 2.1E-02]{.underline}

[Red Marrow 3.3E-03 1.2E-02]{.underline}

[Bone Surfaces 5.0E-03 1.9E-02]{.underline}

[Skin 1.4E-03 5.4E-03]{.underline}

[Spleen 4.1E-03 1.5E-02]{.underline}

[Testes 1.1E-03 4.1E-03]{.underline}

[Thymus 6.1E-03 2.3E-02]{.underline}

[Thyroid 2.5E-03 9.3E-03]{.underline}

[Urinary Bladder Wall 9.8E-03 3.6E-02]{.underline}

[Uterus 2.3E-03 8.5E-03]{.underline}

[Effective Dose Equivalent 1.3E-02 mSv/MBq 4.7E-02 rem/mCi]{.underline}

[Model in ICRP 53 is adopted (data gathered in human subjects). Assumed
distribution and retention:]{.underline}

[ Lungs 85% T]{.underline}~[b]{.underline}~[ = 6 hr 15%
T]{.underline}~[b]{.underline}~[ = 72 hr]{.underline}

[ Liver 25% uptake T]{.underline}~[b]{.underline}~[ = 6 hr, elimination
T]{.underline}~[b]{.underline}~[ = 120 hr]{.underline}

[ Kidneys residence time = 0.108 hr]{.underline}

[Urinary bladder receives clearance from liver and long term clearance
from lung. Dynamic bladder model used with a 4.8 hour voiding
interval.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992 

[ Radiation Dose Estimates for Tc-99m MAG3]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.4E-04 1.6E-03]{.underline}

[Brain 1.0E-04 3.8E-04]{.underline}

[Breasts 1.1E-04 3.9E-04]{.underline}

[Gallbladder Wall 6.7E-04 2.5E-03]{.underline}

[LLI Wall 7.1E-03 2.6E-02]{.underline}

[Small Intestine 2.9E-03 1.1E-02]{.underline}

[Stomach 4.5E-04 1.7E-03]{.underline}

[ULI Wall 2.1E-03 7.8E-03]{.underline}

[Heart Wall 1.8E-04 6.8E-04]{.underline}

[Kidneys 4.1E-03 1.5E-02]{.underline}

[Liver 3.5E-04 1.3E-03]{.underline}

[Lungs 1.5E-04 5.5E-04]{.underline}

[Muscle 1.7E-03 6.3E-03]{.underline}

[Ovaries 6.6E-03 2.5E-02]{.underline}

[Pancreas 4.5E-04 1.7E-03]{.underline}

[Red Marrow 1.1E-03 4.2E-03]{.underline}

[Bone Surfaces 1.5E-03 5.6E-03]{.underline}

[Skin 5.5E-04 2.0E-03]{.underline}

[Spleen 4.1E-04 1.5E-03]{.underline}

[Testes 4.6E-03 1.7E-02]{.underline}

[Thymus 1.3E-04 5.0E-04]{.underline}

[Thyroid 1.3E-04 4.6E-04]{.underline}

[Urinary Bladder Wall 1.4E-01 5.1E-01]{.underline}

[Uterus 1.5E-02 5.5E-02]{.underline}

[Effective Dose Equivalent 1.2E-02 mSv/MBq 4.4E-02 rem/mCi]{.underline}

[Based on the model of Stabin et al. (data gathered in human subjects),
J Nucl Med 33:33-40, 1992. Residence times:]{.underline}

[ Kidneys 0.0757 hr]{.underline}

[ Urinary Bladder 3.3 hr (bladder voided every 4.8 hours)]{.underline}

[ Remainder 0.23 hr]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Tc-99m MDP]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.5E-03 9.1E-03 ]{.underline}

[Brain 1.9E-03 7.0E-03 ]{.underline}

[Breasts 9.5E-04 3.5E-03 ]{.underline}

[Gallbladder Wall 1.9E-03 6.8E-03 ]{.underline}

[LLI Wall 3.4E-03 1.3E-02 ]{.underline}

[Small Intestine 2.4E-03 8.9E-03 ]{.underline}

[Stomach 1.6E-03 5.8E-03 ]{.underline}

[ULI Wall 2.1E-03 7.9E-03 ]{.underline}

[Heart Wall 1.6E-03 6.0E-03 ]{.underline}

[Kidneys 8.6E-03 3.2E-02 ]{.underline}

[Liver 1.6E-03 6.0E-03 ]{.underline}

[Lungs 1.6E-03 5.8E-03 ]{.underline}

[Muscle 1.9E-03 7.2E-03 ]{.underline}

[Ovaries 3.3E-03 1.2E-02 ]{.underline}

[Pancreas 2.1E-03 7.6E-03 ]{.underline}

[Red Marrow 5.4E-03 2.0E-02 ]{.underline}

[Bone Surfaces 3.5E-02 1.3E-01 ]{.underline}

[Skin 1.2E-03 4.3E-03 ]{.underline}

[Spleen 1.8E-03 6.7E-03 ]{.underline}

[Testes 2.3E-03 8.4E-03 ]{.underline}

[Thymus 1.4E-03 5.1E-03 ]{.underline}

[Thyroid 1.7E-03 6.1E-03 ]{.underline}

[Urinary Bladder Wall 3.3E-02 1.2E-01 ]{.underline}

[Uterus 5.1E-03 1.9E-02 ]{.underline}

[Effective Dose Equivalent 6.1E‑03 mSv/MBq 2.2E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 13 (data gathered in
human subjects), J Nucl Med 30:1117-1122, 1989.]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m Sestamibi\* ]{.underline}

[ Estimated Radiation Dose (mGy/MBq) ]{.underline}

[ORGAN Rest patients Stress patients]{.underline}

[Adrenals 4.3E-03 3.9E-03]{.underline}

[Brain 1.8E-03 1.9E-03]{.underline}

[Breasts 1.7E-03 1.6E-03]{.underline}

[Gallbladder Wall 1.8E-02 2.5E-02]{.underline}

[LLI Wall 3.7E-02 2.9E-02]{.underline}

[Small Intestine 2.7E-02 2.2E-02]{.underline}

[Stomach 5.2E-03 4.7E-03]{.underline}

[ULI Wall 5.0E-02 4.0E-02]{.underline}

[Heart Wall 4.4E-03 4.8E-03]{.underline}

[Kidneys 1.8E-02 1.5E-02]{.underline}

[Liver 5.1E-03 3.7E-03]{.underline}

[Lungs 2.4E-03 2.2E-03]{.underline}

[Muscle 3.7E-03 3.3E-03]{.underline}

[Ovaries 1.4E-02 1.2E-02]{.underline}

[Pancreas 5.0E-03 4.6E-03]{.underline}

[Red Marrow 4.5E-03 4.0E-03]{.underline}

[Bone Surfaces 5.8E-03 5.4E-03]{.underline}

[Skin 1.9E-03 1.8E-03]{.underline}

[Spleen 5.2E-03 4.0E-03]{.underline}

[Testes 3.5E-03 3.1E-03]{.underline}

[Thymus 2.3E-03 2.3E-03]{.underline}

[Thyroid 2.2E-03 2.2E-03]{.underline}

[Urinary Bladder Wall 3.7E-02 2.7E-02]{.underline}

[Uterus 1.2E-02 1.0E-02]{.underline}

[Effective Dose Equivalent 1.5E-02 1.3E-02 ]{.underline}

[(mSv/MBq)]{.underline}

[\* Based on data gathered in human volunteers.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Oral Administration of
Tc-99m]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.8E-03 1.0E-02]{.underline}

[Brain 2.3E-06 8.7E-06]{.underline}

[Breasts 3.5E-04 1.3E-03]{.underline}

[Gallbladder Wall 1.4E-02 5.1E-02]{.underline}

[LLI Wall 8.0E-02 3.0E-01]{.underline}

[Small Intestine 5.8E-02 2.1E-01]{.underline}

[Stomach 3.4E-02 1.3E-01]{.underline}

[ULI Wall 1.2E-01 4.3E-01]{.underline}

[Heart Wall 1.3E-03 4.8E-03]{.underline}

[Kidneys 5.6E-03 2.1E-02]{.underline}

[Liver 3.7E-03 1.4E-02]{.underline}

[Lungs 7.0E-04 2.6E-03]{.underline}

[Muscle 3.2E-03 1.2E-02]{.underline}

[Ovaries 2.4E-02 9.0E-02]{.underline}

[Pancreas 7.4E-03 2.7E-02]{.underline}

[Red Marrow 4.6E-03 1.7E-02]{.underline}

[Bone Surfaces 4.1E-03 1.5E-02]{.underline}

[Skin 9.3E-04 3.5E-03]{.underline}

[Spleen 5.0E-03 1.8E-02]{.underline}

[Testes 1.2E-03 4.6E-03]{.underline}

[Thymus 2.3E-04 8.6E-04]{.underline}

[Thyroid 2.3E-05 8.5E-05]{.underline}

[Urinary Bladder Wall 6.6E-03 2.4E-02]{.underline}

[Uterus 1.5E-02 5.6E-02]{.underline}

[Effective Dose Equivalent 2.5E-02 mSv/MBq 9.3E-02 rem/mCi]{.underline}

[Activity follows GI tract kinetics as in ICRP 30, with no absorption
from small intestine (no human or animal data used).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m Pertechnetate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.1E-03 1.1E-02]{.underline}

[Brain 1.8E-03 6.7E-03]{.underline}

[Breasts 1.6E-03 5.8E-03]{.underline}

[Gallbladder Wall 5.2E-03 1.9E-02]{.underline}

[LLI Wall 2.7E-02 1.0E-01]{.underline}

[Small Intestine 8.2E-03 3.0E-02]{.underline}

[Stomach 1.3E-02 4.7E-02]{.underline}

[ULI Wall 2.8E-02 1.0E-01]{.underline}

[Heart Wall 2.7E-03 1.0E-02]{.underline}

[Kidneys 3.3E-03 1.2E-02]{.underline}

[Liver 3.0E-03 1.1E-02]{.underline}

[Lungs 2.3E-03 8.4E-03]{.underline}

[Muscle 2.9E-03 1.1E-02]{.underline}

[Ovaries 8.6E-03 3.2E-02]{.underline}

[Pancreas 4.5E-03 1.7E-02]{.underline}

[Red Marrow 3.3E-03 1.2E-02]{.underline}

[Bone Surfaces 4.8E-03 1.8E-02]{.underline}

[Skin 1.7E-03 6.1E-03]{.underline}

[Spleen 3.5E-03 1.3E-02]{.underline}

[Testes 3.3E-03 1.2E-02]{.underline}

[Thymus 2.2E-03 8.1E-03]{.underline}

[Thyroid 2.3E-02 8.5E-02]{.underline}

[Urinary Bladder Wall 3.6E-02 1.3E-01]{.underline}

[Uterus 8.2E-03 3.0E-02]{.underline}

[Effective Dose Equivalent 1.1E-02 mSv/MBq 3.9E-02 rem/mCi]{.underline}

[Based on the model for \"nonresting patients\" in MIRD Dose Estimate
Report No.8(data gathered in human subjects), J Nucl Med 17:74-77,
1976.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	

                                  February 27, 1995

[ Radiation Dose Estimates for Tc-99m Pyrophosphate]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.3E-03 1.2E-02 ]{.underline}

[Brain 2.6E-03 9.7E-03 ]{.underline}

[Breasts 1.5E-03 5.6E-03 ]{.underline}

[Gallbladder Wall 2.7E-03 1.0E-02 ]{.underline}

[LLI Wall 3.9E-03 1.4E-02 ]{.underline}

[Small Intestine 3.2E-03 1.2E-02 ]{.underline}

[Stomach 2.4E-03 8.8E-03 ]{.underline}

[ULI Wall 2.9E-03 1.1E-02 ]{.underline}

[Heart Wall 2.5E-03 9.3E-03 ]{.underline}

[Kidneys 6.4E-03 2.4E-02 ]{.underline}

[Liver 2.4E-03 9.0E-03 ]{.underline}

[Lungs 2.3E-03 8.7E-03 ]{.underline}

[Muscle 2.6E-03 9.5E-03 ]{.underline}

[Ovaries 3.8E-03 1.4E-02 ]{.underline}

[Pancreas 2.9E-03 1.1E-02 ]{.underline}

[Red Marrow 6.3E-03 2.3E-02 ]{.underline}

[Bone Surfaces 3.8E-02 1.4E-01 ]{.underline}

[Skin 1.6E-03 6.1E-03 ]{.underline}

[Spleen 2.5E-03 9.3E-03 ]{.underline}

[Testes 2.6E-03 9.8E-03 ]{.underline}

[Thymus 2.2E-03 8.1E-03 ]{.underline}

[Thyroid 2.5E-03 9.2E-03 ]{.underline}

[Urinary Bladder Wall 2.4E-02 9.0E-02 ]{.underline}

[Uterus 5.0E-03 1.9E-02 ]{.underline}

[Effective Dose Equivalent 6.0E-03 mSv/MBq 2.2E-02 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 13 (data gathered
in human subjects), (J Nucl Med 30:1117- 1122, 1989)]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m]{.underline}

[ Red Blood Cells - In vitro Labeling]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.0E-03 1.8E-02]{.underline}

[Brain 2.6E-03 9.4E-03]{.underline}

[Breasts 3.0E-03 1.1E-02]{.underline}

[Gallbladder Wall 4.7E-03 1.7E-02]{.underline}

[LLI Wall 4.5E-03 1.7E-02]{.underline}

[Small Intestine 4.2E-03 1.6E-02]{.underline}

[Stomach 4.2E-03 1.6E-02]{.underline}

[ULI Wall 4.1E-03 1.5E-02]{.underline}

[Heart Wall 1.5E-02 5.7E-02]{.underline}

[Kidneys 6.6E-03 2.4E-02]{.underline}

[Liver 6.1E-03 2.3E-02]{.underline}

[Lungs 1.1E-02 4.1E-02]{.underline}

[Muscle 3.4E-03 1.2E-02]{.underline}

[Ovaries 4.7E-03 1.7E-02]{.underline}

[Pancreas 5.3E-03 2.0E-02]{.underline}

[Red Marrow 3.8E-03 1.4E-02]{.underline}

[Bone Surfaces 6.1E-03 2.3E-02]{.underline}

[Skin 2.2E-03 8.0E-03]{.underline}

[Spleen 1.1E-02 4.1E-02]{.underline}

[Testes 3.3E-03 1.2E-02]{.underline}

[Thymus 5.3E-03 1.9E-02]{.underline}

[Thyroid 3.3E-03 1.2E-02]{.underline}

[Urinary Bladder Wall 2.1E-02 7.8E-02]{.underline}

[Uterus 5.8E-03 2.1E-02]{.underline}

[Effective Dose Equivalent 7.3E-03 mSv/MBq 2.7E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 14 (data gathered in
human subjects), J Nucl Med 31:378-380, 1990 (bladder voiding interval
4.8 hours). Blood activity distributed according to the assumed
fractional distribution of blood in model by Hui and
Poston.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	

                                   September 18, 1992

[ Radiation Dose Estimates for Tc-99m ]{.underline}

[ Red Blood Cells - In vivo Labeling]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.4E-03 2.0E-02]{.underline}

[Brain 2.8E-03 1.0E-02]{.underline}

[Breasts 3.3E-03 1.2E-02]{.underline}

[Gallbladder Wall 5.1E-03 1.9E-02]{.underline}

[LLI Wall 4.6E-03 1.7E-02]{.underline}

[Small Intestine 4.5E-03 1.7E-02]{.underline}

[Stomach 4.6E-03 1.7E-02]{.underline}

[ULI Wall 4.4E-03 1.6E-02]{.underline}

[Heart Wall 1.6E-02 5.9E-02]{.underline}

[Kidneys 6.9E-03 2.6E-02]{.underline}

[Liver 6.5E-03 2.4E-02]{.underline}

[Lungs 1.2E-02 4.3E-02]{.underline}

[Muscle 3.6E-03 1.3E-02]{.underline}

[Ovaries 4.7E-03 1.7E-02]{.underline}

[Pancreas 5.7E-03 2.1E-02]{.underline}

[Red Marrow 4.1E-03 1.5E-02]{.underline}

[Bone Surfaces 6.6E-03 2.4E-02]{.underline}

[Skin 2.3E-03 8.7E-03]{.underline}

[Spleen 1.2E-02 4.4E-02]{.underline}

[Testes 3.3E-03 1.2E-02]{.underline}

[Thymus 5.7E-03 2.1E-02]{.underline}

[Thyroid 3.6E-03 1.3E-02]{.underline}

[Urinary Bladder Wall 1.5E-02 5.4E-02]{.underline}

[Uterus 5.4E-03 2.0E-02]{.underline}

[Effective Dose Equivalent 7.2E-03 mSv/MBq 2.7E-02 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 14 (data gathered in
human subjects), J Nucl Med 31:378-380, 1990 (bladder voiding interval
4.8 hours). Blood activity distributed according to the assumed
fractional distribution of blood in model by Hui and
Poston.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Intravenous Administration
of]{.underline}

[ Tc-99m Sulfur Colloid in Normal Patients]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.3E-02 4.8E-02 ]{.underline}

[Brain 2.7E-04 9.9E-04 ]{.underline}

[Breasts 2.1E-03 7.7E-03 ]{.underline}

[Gallbladder Wall 2.4E-02 8.7E-02 ]{.underline}

[LLI Wall 9.6E-04 3.5E-03 ]{.underline}

[Small Intestine 3.8E-03 1.4E-02 ]{.underline}

[Stomach 5.9E-03 2.2E-02 ]{.underline}

[ULI Wall 5.6E-03 2.1E-02 ]{.underline}

[Heart Wall 6.9E-03 2.5E-02 ]{.underline}

[Kidneys 9.6E-03 3.6E-02 ]{.underline}

[Liver 8.6E-02 3.2E-01 ]{.underline}

[Lungs 6.2E-03 2.3E-02 ]{.underline}

[Muscle 2.5E-03 9.2E-03 ]{.underline}

[Ovaries 1.6E-03 5.9E-03 ]{.underline}

[Pancreas 1.3E-02 5.0E-02 ]{.underline}

[Red Marrow 5.2E-03 1.9E-02 ]{.underline}

[Bone Surfaces 5.4E-03 2.0E-02 ]{.underline}

[Skin 1.2E-03 4.4E-03 ]{.underline}

[Spleen 5.3E-04 2.0E-01 ]{.underline}

[Testes 2.2E-04 8.2E-04 ]{.underline}

[Thymus 1.9E-03 7.1E-03 ]{.underline}

[Thyroid 5.1E-04 1.9E-03 ]{.underline}

[Urinary Bladder Wall 6.3E-04 2.3E-03 ]{.underline}

[Uterus 1.3E-03 5.0E-03 ]{.underline}

[Effective Dose Equivalent 1.4E-02 mSv/MBq 5.0E-02 rem/mCi]{.underline}

[Based on model of MIRD Dose Estimate Report No. 3 (data gathered in
human subjects), J Nucl Med 16:108A-108B, 1975.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Intravenous Administration ]{.underline}

[ of Tc-99m Sulfur Colloid in Intermediate-to-Advanced ]{.underline}

[ Diffuse Parenchymal Liver Disease]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.1E-02 4.1E-02 ]{.underline}

[Brain 1.2E-03 4.3E-03 ]{.underline}

[Breasts 1.9E-03 7.1E-03 ]{.underline}

[Gallbladder Wall 1.2E-02 4.3E-02 ]{.underline}

[LLI Wall 2.9E-03 1.1E-02 ]{.underline}

[Small Intestine 4.3E-03 1.6E-02 ]{.underline}

[Stomach 1.0E-02 3.7E-02 ]{.underline}

[ULI Wall 4.8E-03 1.8E-02 ]{.underline}

[Heart Wall 5.4E-03 2.0E-02 ]{.underline}

[Kidneys 1.1E-02 4.1E-02 ]{.underline}

[Liver 3.4E-02 1.3E-01 ]{.underline}

[Lungs 5.0E-03 1.9E-02 ]{.underline}

[Muscle 3.0E-03 1.1E-02 ]{.underline}

[Ovaries 3.2E-03 1.2E-02 ]{.underline}

[Pancreas 1.8E-02 6.5E-02 ]{.underline}

[Red Marrow 1.6E-02 5.8E-02 ]{.underline}

[Bone Surfaces 1.2E-02 4.4E-02 ]{.underline}

[Skin 1.4E-03 5.2E-03 ]{.underline}

[Spleen 2.2E-01 8.1E-01 ]{.underline}

[Testes 8.3E-04 3.1E-03 ]{.underline}

[Thymus 2.2E-03 8.2E-03 ]{.underline}

[Thyroid 1.4E-03 5.1E-03 ]{.underline}

[Urinary Bladder Wall 1.6E-03 6.0E-03 ]{.underline}

[Uterus 2.5E-03 9.4E-03 ]{.underline}

[Effective Dose Equivalent 2.2E-02 mSv/MBq 8.0E-02 rem/mCi]{.underline}

[Based on model of MIRD Dose Estimate Report No. 3 (data gathered in
human subjects), J Nucl Med 16:108A-108B, 1975.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Tc-99m Teboroxime]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.0E-03 1.8E-02]{.underline}

[Brain 3.1E-03 1.1E-02]{.underline}

[Breasts 2.1E-03 7.6E-03]{.underline}

[Gallbladder Wall 3.4E-02 1.3E-01]{.underline}

[LLI Wall 2.5E-02 9.3E-02]{.underline}

[Small Intestine 1.9E-02 7.1E-02]{.underline}

[Stomach 4.7E-03 1.7E-02]{.underline}

[ULI Wall 3.6E-02 1.3E-01]{.underline}

[Heart Wall 2.2E-02 8.0E-02]{.underline}

[Kidneys 4.6E-03 1.7E-02]{.underline}

[Liver 1.7E-02 6.2E-02]{.underline}

[Lungs 7.6E-03 2.8E-02]{.underline}

[Muscle 2.9E-03 1.1E-02]{.underline}

[Ovaries 9.3E-03 3.5E-02]{.underline}

[Pancreas 5.6E-03 2.1E-02]{.underline}

[Red Marrow 3.6E-03 1.3E-02]{.underline}

[Bone Surfaces 4.9E-03 1.8E-02]{.underline}

[Skin 1.5E-03 5.6E-03]{.underline}

[Spleen 3.2E-03 1.2E-02]{.underline}

[Testes 1.9E-03 7.2E-03]{.underline}

[Thymus 3.2E-03 1.2E-02]{.underline}

[Thyroid 1.8E-03 6.6E-03]{.underline}

[Urinary Bladder Wall 1.1E-02 3.9E-02]{.underline}

[Uterus 7.1E-03 2.6E-02]{.underline}

[Effective Dose Equivalent 1.2E-02 mSv/MBq 4.6E-02 rem/mCi]{.underline}

[Based on data gathered in human subjects by Narra et al., J Nucl Med
33:88-93, 1992. Assumed distribution and retention:]{.underline}

[ Brain 2.03% T]{.underline}~[b]{.underline}~[ = 173 hr]{.underline}

[ Liver 27.8% T]{.underline}~[b]{.underline}~[ = 6.0 hr]{.underline}

[ Lungs 13.2% T]{.underline}~[b]{.underline}~[ = 0.073 hr 8.02%
T]{.underline}~[b]{.underline}~[ = 6.2 hr]{.underline}

[ Heart Wall 1.19% T]{.underline}~[b]{.underline}~[ = 3.7 hr 2.05%
T]{.underline}~[b]{.underline}~[ = 0.088 hr]{.underline}

[Gallbladder: receives 1/3 of activity leaving the liver, voids every 6
hours. 26.07% to small intestines, follows GI tract kinetics as in ICRP
30. 71.56% to urinary bladder, T]{.underline}~[b]{.underline}~[ = 47.8
hr. Dynamic bladder model with 4.8-hour voiding interval. Estimate
calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 &
V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for Tc-99m White Blood Cells]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.0E-02 3.9E-02 ]{.underline}

[Brain 1.4E-03 5.2E-03 ]{.underline}

[Breasts 1.8E-03 6.8E-03 ]{.underline}

[Gallbladder Wall 9.8E-03 3.6E-02 ]{.underline}

[LLI Wall 3.5E-03 1.3E-02 ]{.underline}

[Small Intestine 4.6E-03 1.7E-02 ]{.underline}

[Stomach 8.7E-03 3.2E-02 ]{.underline}

[ULI Wall 4.8E-03 1.8E-02 ]{.underline}

[Heart Wall 5.0E-03 1.8E-02 ]{.underline}

[Kidneys 1.0E-02 3.7E-02 ]{.underline}

[Liver 2.7E-02 1.0E-01 ]{.underline}

[Lungs 4.7E-03 1.7E-02 ]{.underline}

[Muscle 2.9E-03 1.1E-02 ]{.underline}

[Ovaries 3.8E-03 1.4E-02 ]{.underline}

[Pancreas 1.5E-02 5.7E-02 ]{.underline}

[Red Marrow 2.3E-02 8.7E-02 ]{.underline}

[Bone Surfaces 1.6E-02 6.0E-02 ]{.underline}

[Skin 1.4E-03 5.1E-03 ]{.underline}

[Spleen 1.8E-01 6.8E-01 ]{.underline}

[Testes 8.4E-04 3.1E-03 ]{.underline}

[Thymus 2.3E-03 8.4E-03 ]{.underline}

[Thyroid 1.5E-03 5.7E-03 ]{.underline}

[Urinary Bladder Wall 1.8E-03 6.8E-03 ]{.underline}

[Uterus 3.0E-03 1.1E-02 ]{.underline}

[Effective Dose Equivalent 2.0E-02 mSv/MBq 7.4E-02 rem/mCi]{.underline}

[Based on assumed model for WBC\'s, from data gathered in patients in
several sources (ICRP 53; Goodwin et al., Third Int. Radiopharm.
Dosimetry Symposium, Oak Ridge, TN, 1980, p. 88-101; Marcus et al. Nucl
Med Comm 9:249-254, 1988; Thakur et al. Semin Nucl Med 14:107-117, 1984;
Weiblen et al. J Lab Clin Med 94:246-255, 1979). Assumed distribution
and retention:]{.underline}

[ Liver 25% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Spleen 25% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Marrow 40% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Remainder 10% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for In-111 DTPA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 6.2E-03 2.3E-02]{.underline}

[Brain 4.8E-03 1.8E-02]{.underline}

[Breasts 3.8E-03 1.4E-02]{.underline}

[Gallbladder Wall 7.2E-03 2.7E-02]{.underline}

[LLI Wall 2.8E-02 1.0E-01]{.underline}

[Small Intestine 1.4E-02 5.4E-02]{.underline}

[Stomach 7.0E-03 2.6E-02]{.underline}

[ULI Wall 1.2E-02 4.4E-02]{.underline}

[Heart Wall 5.6E-03 2.1E-02]{.underline}

[Kidneys 1.4E-02 5.3E-02]{.underline}

[Liver 5.0E-03 1.9E-02]{.underline}

[Lungs 4.6E-03 1.7E-02]{.underline}

[Muscle 8.3E-03 3.1E-02]{.underline}

[Ovaries 2.5E-02 9.4E-02]{.underline}

[Pancreas 6.7E-03 2.5E-02]{.underline}

[Red Marrow 8.2E-03 3.0E-02]{.underline}

[Bone Surfaces 1.0E-02 3.8E-02]{.underline}

[Skin 4.6E-03 1.7E-02]{.underline}

[Spleen 4.8E-03 1.8E-02]{.underline}

[Testes 1.9E-02 6.9E-02]{.underline}

[Thymus 4.6E-03 1.7E-02]{.underline}

[Thyroid 4.5E-03 1.7E-02]{.underline}

[Urinary Bladder Wall 4.3E-01 1.6E+00]{.underline}

[Uterus 5.4E-02 2.0E-01]{.underline}

[Effective Dose Equivalent 4.1E-02 mSv/MBq 1.5E-01 rem/mCi]{.underline}

[Based on data gathered in dogs by McAfee et al., J Nucl Med
20:1273,1278, 1979. Assumed distribution and retention:]{.underline}

[ Liver 2.68% T]{.underline}~[b]{.underline}~[ = 0.17 hr 0.28%
T]{.underline}~[b]{.underline}~[ = 17.3 hr]{.underline}

[ Kidneys 4.18% T]{.underline}~[b]{.underline}~[ = 0.17 hr 0.39%
T]{.underline}~[b]{.underline}~[ = 13.8 hr]{.underline}

[ Spleen 0.226% T]{.underline}~[b]{.underline}~[ = 0.40 hr 0.009%
T]{.underline}~[b]{.underline}~[ = 38.5 hr]{.underline}

[ Small Intestine 3.57% T]{.underline}~[b]{.underline}~[ = 0.23 hr 0.06%
T]{.underline}~[b]{.underline}~[ = 27.7 hr]{.underline}

[ Stomach 1.49% T]{.underline}~[b]{.underline}~[ = 0.87 hr 0.013%
T]{.underline}~[b]{.underline}~[ = 31.5 hr]{.underline}

[ Muscle 21.2% T]{.underline}~[b]{.underline}~[ = 0.54 hr 0.6%
T]{.underline}~[b]{.underline}~[ = 7.7 hr]{.underline}

[ Total Body 79.7% T]{.underline}~[b]{.underline}~[ = 0.51 hr 20.3%
T]{.underline}~[b]{.underline}~[ = 7.86 hr]{.underline}

[ Clearance through urinary bladder. Bladder voiding interval 4.8
hours.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for In-111 Platelets]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.8E-01 1.1E+00 ]{.underline}

[Brain 8.3E-02 3.1E-01 ]{.underline}

[Breasts 9.0E-02 3.3E-01 ]{.underline}

[Gallbladder Wall 2.7E-01 1.0E+00 ]{.underline}

[LLI Wall 1.4E-01 5.0E-01 ]{.underline}

[Small Intestine 1.6E-01 6.0E-01 ]{.underline}

[Stomach 3.1E-01 1.1E+00 ]{.underline}

[ULI Wall 1.7E-01 6.2E-01 ]{.underline}

[Heart Wall 1.8E-01 6.5E-01 ]{.underline}

[Kidneys 3.1E-01 1.1E+00 ]{.underline}

[Liver 5.6E-01 2.1E+00 ]{.underline}

[Lungs 1.6E-01 6.1E-01 ]{.underline}

[Muscle 1.3E-01 4.7E-01 ]{.underline}

[Ovaries 1.4E-01 5.3E-01 ]{.underline}

[Pancreas 4.9E-01 1.8E+00 ]{.underline}

[Red Marrow 1.7E-01 6.3E-01 ]{.underline}

[Bone Surfaces 2.1E-01 7.7E-01 ]{.underline}

[Skin 7.5E-02 2.8E-01 ]{.underline}

[Spleen 5.2E+00 1.9E+01 ]{.underline}

[Testes 9.0E-02 3.3E-01 ]{.underline}

[Thymus 1.1E-01 4.2E-01 ]{.underline}

[Thyroid 1.0E-01 3.7E-01 ]{.underline}

[Urinary Bladder Wall 1.8E-01 6.7E-01 ]{.underline}

[Uterus 1.4E-01 5.3E-01 ]{.underline}

[Effective Dose Equivalent 5.1E-01 mSv/MBq 1.9E+00 rem/mCi]{.underline}

[Based on data gathered in patients by Goodwin et al., Third Int.
Radiopharm. Dosimetry Symposium, Oak Ridge, TN, 1980, p. 88-101. Assumed
distribution and retention: Initial uptake:]{.underline}

[ Liver 8.5%, Spleen 23.5%]{.underline}

[Platelets have a 9 day survival time, and then are transported to
destruction sites, where they have a 10 day biological half
time:]{.underline}

[ Liver 50%, Spleen 25%, Marrow 25%]{.underline}

[After leaving the destruction sites, activity is cleared through the
urinary bladder with a 6.6 day biological half time. Bladder voiding
interval 4.8]{.underline}

[hours.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for In-111 Red Blood Cells]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.9E-01 7.0E-01 ]{.underline}

[Brain 1.3E-01 4.7E-01 ]{.underline}

[Breasts 1.1E-01 4.0E-01 ]{.underline}

[Gallbladder Wall 1.9E-01 7.0E-01 ]{.underline}

[LLI Wall 1.8E-01 6.7E-01 ]{.underline}

[Small Intestine 1.9E-01 6.9E-01 ]{.underline}

[Stomach 1.9E-01 6.9E-01 ]{.underline}

[ULI Wall 1.8E-01 6.7E-01 ]{.underline}

[Heart Wall 1.7E-01 6.3E-01 ]{.underline}

[Kidneys 1.8E-01 6.7E-01 ]{.underline}

[Liver 1.7E-01 6.5E-01 ]{.underline}

[Lungs 1.5E-01 5.6E-01 ]{.underline}

[Muscle 1.4E-01 5.2E-01 ]{.underline}

[Ovaries 1.9E-01 7.0E-01 ]{.underline}

[Pancreas 2.2E-01 8.3E-01 ]{.underline}

[Red Marrow 1.5E-01 5.4E-01 ]{.underline}

[Bone Surfaces 2.2E-01 8.3E-01 ]{.underline}

[Skin 9.6E-02 3.5E-01 ]{.underline}

[Spleen 7.6E-01 2.8E+00 ]{.underline}

[Testes 1.4E-01 5.0E-01 ]{.underline}

[Thymus 1.5E-01 5.6E-01 ]{.underline}

[Thyroid 1.5E-01 5.6E-01 ]{.underline}

[Urinary Bladder Wall 1.7E-01 6.5E-01 ]{.underline}

[Uterus 1.9E-01 7.0E-01 ]{.underline}

[Effective Dose Equivalent 2.0E-01 mSv/MBq 7.5E-01 rem/mCi]{.underline}

[Based on model in humans for Cr-51 RBC\'s by Powsner and Raeside,
Diagnostic Nuclear Medicine, 1971, p. 184. Assumed distribution and
retention:]{.underline}

[ 100% to blood, T]{.underline}~[b]{.underline}~[ = 35 days]{.underline}

[Of material removed from blood:]{.underline}

[ Liver 40% T]{.underline}~[b]{.underline}~[ = 50 days]{.underline}

[ Spleen 40% T]{.underline}~[b]{.underline}~[ = 50 days]{.underline}

[ Marrow 20% T]{.underline}~[b]{.underline}~[ = 50 days]{.underline}

[Clearance through urinary bladder. Bladder voiding interval 4.8
hours.]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	February 27, 1995

[ Radiation Dose Estimates for In-111 White Blood Cells]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.6E-01 1.3E+00 ]{.underline}

[Brain 5.1E-02 1.9E-01 ]{.underline}

[Breasts 6.7E-02 2.5E-01 ]{.underline}

[Gallbladder Wall 3.4E-01 1.2E+00 ]{.underline}

[LLI Wall 1.2E-01 4.6E-01 ]{.underline}

[Small Intestine 1.6E-01 5.7E-01 ]{.underline}

[Stomach 2.9E-01 1.1E+00 ]{.underline}

[ULI Wall 1.6E-01 6.0E-01 ]{.underline}

[Heart Wall 1.7E-01 6.2E-01 ]{.underline}

[Kidneys 3.5E-01 1.3E+00 ]{.underline}

[Liver 9.0E-01 3.3E+00 ]{.underline}

[Lungs 1.6E-01 6.0E-01 ]{.underline}

[Muscle 1.0E-01 3.9E-01 ]{.underline}

[Ovaries 1.3E-01 4.8E-01 ]{.underline}

[Pancreas 5.5E-01 2.0E+00 ]{.underline}

[Red Marrow 6.5E-01 2.4E+00 ]{.underline}

[Bone Surfaces 4.6E-01 1.7E+00 ]{.underline}

[Skin 5.0E-02 1.9E-01 ]{.underline}

[Spleen 5.9E+00 2.2E+01 ]{.underline}

[Testes 3.0E-02 1.1E-01 ]{.underline}

[Thymus 7.9E-02 2.9E-01 ]{.underline}

[Thyroid 5.4E-02 2.0E-01 ]{.underline}

[Urinary Bladder Wall 6.4E-02 2.4E-01 ]{.underline}

[Uterus 1.0E-01 3.8E-01 ]{.underline}

[Effective Dose Equivalent 6.4E-01 mSv/MBq 2.4E+00 rem/mCi]{.underline}

[Based on assumed model for WBC\'s, from data gathered in patients in
several sources (ICRP 53; Goodwin et al., Third Int. Radiopharm.
Dosimetry Symposium, Oak Ridge, TN, 1980, p. 88-101; Marcus et al. Nucl
Med Comm 9:249-254, 1988; Thakur et al. Semin Nucl Med 14:107-117, 1984;
Weiblen et al. J Lab Clin Med 94:246-255, 1979). Assumed distribution
and retention:]{.underline}

[ Liver 25% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Spleen 25% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Marrow 40% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[ Remainder 10% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

    Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7).  Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds. CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514‑534.) used.

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for I-123 Hippuran]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 7.7E-04 2.8E-03]{.underline}

[Brain 1.7E-04 6.1E-04]{.underline}

[Breasts 1.7E-04 6.4E-04]{.underline}

[Gallbladder Wall 1.0E-03 3.8E-03]{.underline}

[LLI Wall 1.1E-02 4.2E-02]{.underline}

[Small Intestine 4.1E-03 1.5E-02]{.underline}

[Stomach 7.0E-04 2.6E-03]{.underline}

[ULI Wall 3.1E-03 1.1E-02]{.underline}

[Heart Wall 2.8E-04 1.0E-03]{.underline}

[Kidneys 9.9E-03 3.7E-02]{.underline}

[Liver 5.6E-04 2.1E-03]{.underline}

[Lungs 2.4E-04 8.8E-04]{.underline}

[Muscle 2.8E-03 1.1E-02]{.underline}

[Ovaries 1.0E-02 3.7E-02]{.underline}

[Pancreas 7.2E-04 2.6E-03]{.underline}

[Red Marrow 1.7E-03 6.1E-03]{.underline}

[Bone Surfaces 2.0E-03 7.4E-03]{.underline}

[Skin 9.0E-04 3.3E-03]{.underline}

[Spleen 7.3E-04 2.7E-03]{.underline}

[Testes 7.0E-03 2.6E-02]{.underline}

[Thymus 2.1E-04 7.8E-04]{.underline}

[Thyroid 1.9E-04 7.1E-04]{.underline}

[Urinary Bladder Wall 3.0E-01 1.1E+00]{.underline}

[Uterus 2.6E-02 9.5E-02]{.underline}

[Effective Dose Equivalent 2.4E-02 mSv/MBq 8.8E-02 rem/mCi]{.underline}

[Based on data gathered in patients by Lindmo et al. (Med Phys
1(4):193-197, 1974). Assumed distribution and retention:]{.underline}

[Total body 49% T]{.underline}~[b]{.underline}~[ = 0.285 hr 51%
T]{.underline}~[b]{.underline}~[ = 0.0392 hr]{.underline}

[Kidney Residence time = 6.2 minutes]{.underline}

[All activity cleared through urinary bladder. Dynamic bladder model
with 4.8-hour voiding interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-123 IMP]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.3E-02 4.6E-02]{.underline}

[Brain 1.9E-02 7.1E-02]{.underline}

[Breasts 8.9E-03 3.3E-02]{.underline}

[Gallbladder Wall 1.2E-02 4.4E-02]{.underline}

[LLI Wall 1.4E-02 5.0E-02]{.underline}

[Small Intestine 1.3E-02 4.7E-02]{.underline}

[Stomach 1.2E-02 4.3E-02]{.underline}

[ULI Wall 1.2E-02 4.4E-02]{.underline}

[Heart Wall 1.4E-02 5.1E-02]{.underline}

[Kidneys 1.1E-02 4.0E-02]{.underline}

[Liver 9.0E-03 3.3E-02]{.underline}

[Lungs 4.2E-02 1.6E-01]{.underline}

[Muscle 1.0E-02 3.8E-02]{.underline}

[Ovaries 1.4E-02 5.1E-02]{.underline}

[Pancreas 1.3E-02 4.8E-02]{.underline}

[Red Marrow 1.1E-02 4.1E-02]{.underline}

[Bone Surfaces 1.9E-02 7.0E-02]{.underline}

[Skin 7.1E-03 2.6E-02]{.underline}

[Spleen 1.2E-02 4.4E-02]{.underline}

[Testes 1.0E-02 3.8E-02]{.underline}

[Thymus 1.2E-02 4.3E-02]{.underline}

[Thyroid 1.1E-02 4.1E-02]{.underline}

[Urinary Bladder Wall 5.7E-02 2.1E-01]{.underline}

[Uterus 1.6E-02 6.0E-02]{.underline}

[Effective Dose Equivalent 1.9E-02 mSv/MBq 7.1E-02 rem/mCi]{.underline}

[Based on data gathered in six human volunteers. Average residence
times:]{.underline}

[ Brain 0.60 hr]{.underline}

[ Liver 0.165 hr]{.underline}

[ Lungs 1.46 hr]{.underline}

[ Remainder 11.5 hr]{.underline}

[Urinary bladder: 100%, T]{.underline}~[b]{.underline}~[ = 34.1 hr.
Bladder voiding interval 4.8 hours.]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-123 mIBG]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.6E-02 5.9E-02]{.underline}

[Brain 4.8E-03 1.8E-02]{.underline}

[Breasts 5.2E-03 1.9E-02]{.underline}

[Gallbladder Wall 2.2E-02 8.0E-02]{.underline}

[LLI Wall 9.8E-03 3.6E-02]{.underline}

[Small Intestine 9.3E-03 3.4E-02]{.underline}

[Stomach 8.6E-03 3.2E-02]{.underline}

[ULI Wall 9.9E-03 3.6E-02]{.underline}

[Heart Wall 1.8E-02 6.7E-02]{.underline}

[Kidneys 1.1E-02 3.9E-02]{.underline}

[Liver 7.3E-02 2.7E-01]{.underline}

[Lungs 9.3E-03 3.4E-02]{.underline}

[Muscle 7.1E-03 2.6E-02]{.underline}

[Ovaries 9.9E-03 3.7E-02]{.underline}

[Pancreas 1.3E-02 4.9E-02]{.underline}

[Red Marrow 7.1E-03 2.6E-02]{.underline}

[Bone Surfaces 1.2E-02 4.3E-02]{.underline}

[Salivary Glands 2.5E-02 9.4E-02]{.underline}

[Skin 4.4E-03 1.6E-02]{.underline}

[Spleen 2.1E-02 7.7E-02]{.underline}

[Testes 6.9E-03 2.6E-02]{.underline}

[Thymus 6.6E-03 2.5E-02]{.underline}

[Thyroid 4.7E-03 1.7E-02]{.underline}

[Urinary Bladder Wall 9.4E-02 3.5E-01]{.underline}

[Uterus 1.4E-02 5.4E-02]{.underline}

[Effective Dose Equivalent 1.9E-02 mSv/MBq 7.1E-02 rem/mCi]{.underline}

[Based on data gathered in patients - Jacobsson et al, 4th
International]{.underline}

[Radiopharmaceutical Dosimetry Symposium, CONF-851113, pp. 389-398.
Assumed distribution and retention:]{.underline}

[Total body 63 % T]{.underline}~[b]{.underline}~[ = 32.8 hours 36 %
T]{.underline}~[b]{.underline}~[ = 3.05 hours]{.underline}

[ 1 % T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Liver 21 % T]{.underline}~[b]{.underline}~[ = 32.8 hours 15 %
T]{.underline}~[b]{.underline}~[ = 3.05 hours]{.underline}

[ 0.3 % T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Spleen 0.6 % T]{.underline}~[b]{.underline}~[ = 178 hours]{.underline}

[Sal. glands 0.04 % T]{.underline}~[b]{.underline}~[ = 32.8
hours]{.underline}

[Thyroid 0.005 % T]{.underline}~[b]{.underline}~[ = 168
hours]{.underline}

[Adrenals 0.02 % T]{.underline}~[b]{.underline}~[ = 48.6
hours]{.underline}

[Heart wall 0.8 % T]{.underline}~[b]{.underline}~[ = 120
hours]{.underline}

    Dynamic Bladder Model used (4.80 hour void)

`      36 %     T`~`b`~` =  3.00 hours``	``63 %     T`~`b`~` =  33.6 hours`

    Dose to salivary glands is self-dose only, based on 77 g mass and photon absorbed

    fractions from MIRD Pamphlet No. 8.  Salivary gland activity did not contribute to other organ doses.  Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information about risk to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for I-123 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.1E-03 1.9E-02]{.underline}

[Brain 4.7E-03 1.8E-02]{.underline}

[Breasts 3.0E-03 1.1E-02]{.underline}

[Gallbladder Wall 7.3E-03 2.7E-02]{.underline}

[LLI Wall 1.1E-02 4.0E-02]{.underline}

[Small Intestine 3.3E-02 1.2E-01]{.underline}

[Stomach 5.5E-02 2.0E-01]{.underline}

[ULI Wall 1.4E-02 5.0E-02]{.underline}

[Heart Wall 5.1E-03 1.9E-02]{.underline}

[Kidneys 5.5E-03 2.0E-02]{.underline}

[Liver 4.9E-03 1.8E-02]{.underline}

[Lungs 4.9E-03 1.8E-02]{.underline}

[Muscle 6.8E-03 2.5E-02]{.underline}

[Ovaries 1.2E-02 4.4E-02]{.underline}

[Pancreas 1.0E-02 3.8E-02]{.underline}

[Red Marrow 5.8E-03 2.2E-02]{.underline}

[Bone Surfaces 9.8E-03 3.6E-02]{.underline}

[Skin 3.3E-03 1.2E-02]{.underline}

[Spleen 7.3E-03 2.7E-02]{.underline}

[Testes 5.1E-03 1.9E-02]{.underline}

[Thymus 5.6E-03 2.1E-02]{.underline}

[Thyroid 3.4E+00 1.3E+01]{.underline}

[Urinary Bladder Wall 9.6E-02 3.6E-01]{.underline}

[Uterus 1.6E-02 5.9E-02]{.underline}

[Effective Dose Equivalent 1.2E-01 mSv/MBq 4.5E-01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5 (data gathered in
human subjects), J Nucl Med 16:857-860, 1975 (25% thyroid
uptake).]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	March 18, 1993

[ Radiation Dose Estimates for I-124 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.8E-02 2.1E-01]{.underline}

[Brain 1.5E-01 5.7E-01]{.underline}

[Breasts 6.2E-02 2.3E-01]{.underline}

[Gallbladder Wall 7.1E-02 2.6E-01]{.underline}

[LLI Wall 7.9E-02 2.9E-01]{.underline}

[Small Intestine 2.8E-01 1.0E+00]{.underline}

[Stomach 4.5E-01 1.7E+00]{.underline}

[ULI Wall 9.9E-02 3.7E-01]{.underline}

[Heart Wall 8.4E-02 3.1E-01]{.underline}

[Kidneys 5.4E-02 2.0E-01]{.underline}

[Liver 9.7E-02 3.6E-01]{.underline}

[Lungs 1.1E-01 4.1E-01]{.underline}

[Muscle 1.4E-01 5.3E-01]{.underline}

[Ovaries 8.8E-02 3.2E-01]{.underline}

[Pancreas 8.8E-02 3.3E-01]{.underline}

[Red Marrow 1.1E-01 4.2E-01]{.underline}

[Bone Surfaces 1.3E-01 4.7E-01]{.underline}

[Skin 7.2E-02 2.7E-01]{.underline}

[Spleen 6.6E-02 2.4E-01]{.underline}

[Testes 4.3E-02 1.6E-01]{.underline}

[Thymus 1.7E-01 6.3E-01]{.underline}

[Thyroid 2.1E+02 7.8E+02]{.underline}

[Urinary Bladder Wall 7.9E-01 2.9E+00]{.underline}

[Uterus 1.1E-01 4.2E-01]{.underline}

[Effective Dose Equivalent 6.5E+00 mSv/MBq 2.4E+01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5 (data gathered in
human subjects), J Nucl Med 16:857-860, 1975 (25% thyroid
uptake).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	March 25, 1993

[ Radiation Dose Estimates for I-125 Fibrinogen\*]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.8E-02 2.1E-01]{.underline}

[Brain 6.0E-02 2.2E-01]{.underline}

[Breasts 4.4E-02 1.6E-01]{.underline}

[Gallbladder Wall 6.8E-02 2.5E-01]{.underline}

[LLI Wall 6.0E-02 2.2E-01]{.underline}

[Small Intestine 8.7E-02 3.2E-01]{.underline}

[Stomach 1.1E-01 4.1E-01]{.underline}

[ULI Wall 6.2E-02 2.3E-01]{.underline}

[Heart Wall 5.6E-02 2.1E-01]{.underline}

[Kidneys 5.4E-02 2.0E-01]{.underline}

[Liver 1.3E-01 4.9E-01]{.underline}

[Lungs 6.9E-02 2.5E-01]{.underline}

[Muscle 1.3E-01 4.8E-01]{.underline}

[Ovaries 6.0E-02 2.2E-01]{.underline}

[Pancreas 6.3E-02 2.3E-01]{.underline}

[Red Marrow 5.4E-02 2.0E-01]{.underline}

[Bone Surfaces 1.9E-01 7.0E-01]{.underline}

[Skin 5.0E-02 1.9E-01]{.underline}

[Spleen 5.5E-02 2.1E-01]{.underline}

[Testes 4.8E-02 1.8E-01]{.underline}

[Thymus 6.9E-02 2.6E-01]{.underline}

[Thyroid 2.1E+02 7.8E+02]{.underline}

[Urinary Bladder Wall 1.7E-01 6.1E-01]{.underline}

[Uterus 6.3E-02 2.3E-01]{.underline}

[Effective Dose Equivalent 6.4E+00 mSv/MBq 2.4E+01 rem/mCi]{.underline}

[\* Based on kinetic model in Wootton and Hammond (Brit J Radiol
51:265-272, 1978).]{.underline}

[ Free iodide treated as in MIRD Dose Estimate Report No. 5 (J Nucl Med
16:857]{.underline}

[ -860, 1975).]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-125 IMP]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.0E-02 7.3E-02]{.underline}

[Brain 2.8E-02 1.0E-01]{.underline}

[Breasts 1.6E-02 6.1E-02]{.underline}

[Gallbladder Wall 1.9E-02 7.0E-02]{.underline}

[LLI Wall 2.2E-02 8.1E-02]{.underline}

[Small Intestine 2.1E-02 7.6E-02]{.underline}

[Stomach 2.0E-02 7.3E-02]{.underline}

[ULI Wall 2.0E-02 7.2E-02]{.underline}

[Heart Wall 2.1E-02 7.9E-02]{.underline}

[Kidneys 1.8E-02 6.8E-02]{.underline}

[Liver 9.4E-03 3.5E-02]{.underline}

[Lungs 7.2E-02 2.7E-01]{.underline}

[Muscle 1.9E-02 6.9E-02]{.underline}

[Ovaries 2.1E-02 7.9E-02]{.underline}

[Pancreas 2.0E-02 7.5E-02]{.underline}

[Red Marrow 1.5E-02 5.7E-02]{.underline}

[Bone Surfaces 3.9E-02 1.5E-01]{.underline}

[Skin 1.4E-02 5.0E-02]{.underline}

[Spleen 2.0E-02 7.4E-02]{.underline}

[Testes 1.8E-02 6.5E-02]{.underline}

[Thymus 1.9E-02 7.1E-02]{.underline}

[Thyroid 2.0E-02 7.2E-02]{.underline}

[Urinary Bladder Wall 1.4E-01 5.0E-01]{.underline}

[Uterus 2.5E-02 9.4E-02]{.underline}

[Effective Dose Equivalent 3.4E-02 mSv/MBq 1.3E-01 rem/mCi]{.underline}

[Based on data gathered in six human volunteers. Average residence
times:]{.underline}

[ Brain 1.34 hr]{.underline}

[ Liver 0.349 hr]{.underline}

[ Lungs 3.45 hr]{.underline}

[ Remainder 42.9 hr]{.underline}

[Urinary bladder: 100%, T]{.underline}~[b]{.underline}~[ = 34.1 hr.
Dynamic bladder model with 4.8-hour voiding interval.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information to individual patients.]{.underline}

    Source: Radiation Internal Dose

            Information Center

    	 

[September 18, 1992]{.underline}

[ Radiation Dose Estimates for I-125 mIBG ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.2E-02 1.6E-01]{.underline}

[Brain 1.4E-02 5.3E-02]{.underline}

[Breasts 1.2E-02 4.5E-02]{.underline}

[Gallbladder Wall 4.3E-02 1.6E-01]{.underline}

[LLI Wall 1.7E-02 6.1E-02]{.underline}

[Small Intestine 1.6E-02 5.9E-02]{.underline}

[Stomach 1.7E-02 6.4E-02]{.underline}

[ULI Wall 1.7E-02 6.2E-02]{.underline}

[Heart Wall 8.3E-02 3.1E-01]{.underline}

[Kidneys 2.0E-02 7.4E-02]{.underline}

[Liver 2.2E-01 8.2E-01]{.underline}

[Lungs 2.3E-02 8.3E-02]{.underline}

[Muscle 1.6E-02 5.8E-02]{.underline}

[Ovaries 1.6E-02 5.9E-02]{.underline}

[Pancreas 2.6E-02 9.6E-02]{.underline}

[Red Marrow 1.2E-02 4.4E-02]{.underline}

[Bone Surfaces 3.1E-02 1.2E-01]{.underline}

[Salivary Glands 7.0E-02 2.6E-01]{.underline}

[Skin 1.1E-02 3.9E-02]{.underline}

[Spleen 1.6E-01 5.9E-01]{.underline}

[Testes 1.3E-02 4.8E-02]{.underline}

[Thymus 1.5E-02 5.7E-02]{.underline}

[Thyroid 4.6E-02 1.7E-01]{.underline}

[Urinary Bladder Wall 1.4E-01 5.1E-01]{.underline}

[Uterus 2.0E-02 7.5E-02]{.underline}

[Effective Dose Equivalent 5.1E-02 mSv/MBq 1.9E-01 rem/mCi]{.underline}

[Based on data gathered in patients - Jacobsson et al, 4th
International]{.underline}

[Radiopharmaceutical Dosimetry Symposium, CONF-851113, pp. 389-398.
Assumed distribution and retention:]{.underline}

[Total body 63% T]{.underline}~[b]{.underline}~[ = 32.8 hours 36%
T]{.underline}~[b]{.underline}~[ = 3.05 hours]{.underline}

[ 1% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Liver 21% T]{.underline}~[b]{.underline}~[ = 32.8 hours 15%
T]{.underline}~[b]{.underline}~[ = 3.05 hours]{.underline}

[ 0.3% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Spleen 0.6% T]{.underline}~[b]{.underline}~[ = 178 hours]{.underline}

[Sal. glands 0.04% T]{.underline}~[b]{.underline}~[ = 32.8
hours]{.underline}

[Thyroid 0.005% T]{.underline}~[b]{.underline}~[ = 168
hours]{.underline}

[Adrenals 0.02% T]{.underline}~[b]{.underline}~[ = 48.6
hours]{.underline}

[Heart wall 0.8% T]{.underline}~[b]{.underline}~[ = 120
hours]{.underline}

[Dynamic Bladder Model used (4.80 hour void)]{.underline}

[ 36% T]{.underline}~[b]{.underline}~[ = 3.00 hours 63%
T]{.underline}~[b]{.underline}~[ = 33.6 hours]{.underline}

[Dose to salivary glands is self-dose only, based on 77 g mass and
photon absorbed]{.underline}

[fractions from MIRD Pamphlet No. 8. Salivary gland activity did not
contribute to other organ doses. Estimate calculated using phantom of
Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose ]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-125 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.1E-02 4.0E-02]{.underline}

[Brain 1.3E-02 4.7E-02]{.underline}

[Breasts 6.2E-03 2.3E-02]{.underline}

[Gallbladder Wall 1.9E-02 6.8E-02]{.underline}

[LLI Wall 1.1E-02 4.2E-02]{.underline}

[Small Intestine 3.7E-02 1.4E-01]{.underline}

[Stomach 6.4E-02 2.4E-01]{.underline}

[ULI Wall 1.5E-02 5.5E-02]{.underline}

[Heart Wall 9.1E-03 3.4E-02]{.underline}

[Kidneys 8.6E-03 3.2E-02]{.underline}

[Liver 8.6E-02 3.2E-01]{.underline}

[Lungs 1.9E-02 7.1E-02]{.underline}

[Muscle 8.6E-02 3.2E-01]{.underline}

[Ovaries 1.1E-02 4.1E-02]{.underline}

[Pancreas 1.3E-02 4.9E-02]{.underline}

[Red Marrow 1.7E-02 6.3E-02]{.underline}

[Bone Surfaces 9.9E-02 3.6E-01]{.underline}

[Skin 1.7E-02 6.4E-02]{.underline}

[Spleen 8.4E-03 3.1E-02]{.underline}

[Testes 6.5E-03 2.4E-02]{.underline}

[Thymus 2.4E-02 8.9E-02]{.underline}

[Thyroid 2.1E+02 7.8E+02]{.underline}

[Urinary Bladder Wall 1.2E-01 4.4E-01]{.underline}

[Uterus 1.4E-02 5.2E-02]{.underline}

[Effective Dose Equivalent 6.4E+00 mSv/MBq 2.4E+01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5, J Nucl Med
16:857-860, 1975 (25% thyroid uptake).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	March 18, 1993

[ Radiation Dose Estimates for I-126 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.9E-02 1.8E-01]{.underline}

[Brain 1.7E-01 6.4E-01]{.underline}

[Breasts 6.0E-02 2.2E-01]{.underline}

[Gallbladder Wall 5.7E-02 2.1E-01]{.underline}

[LLI Wall 4.6E-02 1.7E-01]{.underline}

[Small Intestine 2.0E-01 7.5E-01]{.underline}

[Stomach 3.1E-01 1.2E+00]{.underline}

[ULI Wall 5.9E-02 2.2E-01]{.underline}

[Heart Wall 8.1E-02 3.0E-01]{.underline}

[Kidneys 4.2E-02 1.6E-01]{.underline}

[Liver 1.5E-01 5.6E-01]{.underline}

[Lungs 1.2E-01 4.4E-01]{.underline}

[Muscle 1.6E-01 5.8E-01]{.underline}

[Ovaries 5.1E-02 1.9E-01]{.underline}

[Pancreas 6.2E-02 2.3E-01]{.underline}

[Red Marrow 1.2E-01 4.4E-01]{.underline}

[Bone Surfaces 1.5E-01 5.4E-01]{.underline}

[Skin 7.5E-02 2.8E-01]{.underline}

[Spleen 4.7E-02 1.8E-01]{.underline}

[Testes 2.8E-02 1.0E-01]{.underline}

[Thymus 1.9E-01 7.0E-01]{.underline}

[Thyroid 4.2E+02 1.6E+03]{.underline}

[Urinary Bladder Wall 5.4E-01 2.0E+00]{.underline}

[Uterus 6.4E-02 2.3E-01]{.underline}

[Effective Dose Equivalent 1.3E+01 mSv/MBq 4.7E+01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5 (data gathered in
human subjects), J Nucl Med 16:857-860, 1975 (25% thyroid
uptake).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	March 18, 1993

[ Radiation Dose Estimates for I-130 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.1E-02 1.9E-01]{.underline}

[Brain 4.7E-02 1.7E-01]{.underline}

[Breasts 3.1E-02 1.2E-01]{.underline}

[Gallbladder Wall 7.1E-02 2.6E-01]{.underline}

[LLI Wall 9.9E-02 3.7E-01]{.underline}

[Small Intestine 3.2E-01 1.2E+00]{.underline}

[Stomach 5.2E-01 1.9E+00]{.underline}

[ULI Wall 1.2E-01 4.6E-01]{.underline}

[Heart Wall 5.0E-02 1.9E-01]{.underline}

[Kidneys 5.4E-02 2.0E-01]{.underline}

[Liver 5.0E-02 1.9E-01]{.underline}

[Lungs 4.7E-02 1.7E-01]{.underline}

[Muscle 6.4E-02 2.3E-01]{.underline}

[Ovaries 1.1E-01 4.1E-01]{.underline}

[Pancreas 9.6E-02 3.6E-01]{.underline}

[Red Marrow 6.2E-02 2.3E-01]{.underline}

[Bone Surfaces 5.4E-02 2.0E-01]{.underline}

[Skin 3.5E-02 1.3E-01]{.underline}

[Spleen 7.0E-02 2.6E-01]{.underline}

[Testes 5.0E-02 1.9E-01]{.underline}

[Thymus 5.6E-02 2.1E-01]{.underline}

[Thyroid 3.1E+01 1.1E+02]{.underline}

[Urinary Bladder Wall 8.9E-01 3.3E+00]{.underline}

[Uterus 1.5E-01 5.5E-01]{.underline}

[Effective Dose Equivalent 1.1E+00 mSv/MBq 4.0E+00 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5 (data gathered in
human subjects), J Nucl Med 16:857-860, 1975 (25% thyroid
uptake).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

[ September 18, 1992]{.underline}

[ Radiation Dose Estimates for I-131 Hippuran]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.1E-03 7.7E-03]{.underline}

[Brain 5.5E-04 2.1E-03]{.underline}

[Breasts 6.7E-04 2.5E-03]{.underline}

[Gallbladder Wall 3.0E-03 1.1E-02]{.underline}

[LLI Wall 2.6E-02 9.5E-02]{.underline}

[Small Intestine 1.0E-02 3.8E-02]{.underline}

[Stomach 2.1E-03 7.7E-03]{.underline}

[ULI Wall 8.0E-03 2.9E-02]{.underline}

[Heart Wall 9.0E-04 3.3E-03]{.underline}

[Kidneys 4.5E-02 1.7E-01]{.underline}

[Liver 1.7E-03 6.4E-03]{.underline}

[Lungs 7.7E-04 2.8E-03]{.underline}

[Muscle 6.7E-03 2.5E-02]{.underline}

[Ovaries 2.3E-02 8.6E-02]{.underline}

[Pancreas 2.1E-03 7.7E-03]{.underline}

[Red Marrow 4.8E-03 1.8E-02]{.underline}

[Bone Surfaces 3.6E-03 1.3E-02]{.underline}

[Skin 2.6E-03 9.6E-03]{.underline}

[Spleen 2.0E-03 7.5E-03]{.underline}

[Testes 1.7E-02 6.4E-02]{.underline}

[Thymus 7.3E-04 2.7E-03]{.underline}

[Thyroid 6.4E-04 2.4E-03]{.underline}

[Urinary Bladder Wall 1.4E+00 5.3E+00]{.underline}

[Uterus 5.4E-02 2.0E-01]{.underline}

[Effective Dose Equivalent 1.0E-01 mSv/MBq 3.7E-01 rem/mCi]{.underline}

[Based on data gathered in patients by Lindmo et al. (Med Phys
1(4):193-197, 1974). Assumed distribution and retention:]{.underline}

[Total body 49% T]{.underline}~[b]{.underline}~[ = 0.285 hr 51%
T]{.underline}~[b]{.underline}~[ = 0.0392 hr]{.underline}

[Kidney Residence time = 6.2 minutes]{.underline}

[All activity cleared through urinary bladder. Bladder voiding interval
4.8 hours.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for I-131 HSA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 5.3E-01 2.0E+00]{.underline}

[Brain 1.0E+00 3.8E+00]{.underline}

[Breasts 4.0E-01 1.5E+00]{.underline}

[Gallbladder Wall 5.0E-01 1.9E+00]{.underline}

[LLI Wall 4.1E-01 1.5E+00]{.underline}

[Small Intestine 4.3E-01 1.6E+00]{.underline}

[Stomach 4.7E-01 1.7E+00]{.underline}

[ULI Wall 4.3E-01 1.6E+00]{.underline}

[Heart Wall 3.0E+00 1.1E+01]{.underline}

[Kidneys 1.2E+00 4.6E+00]{.underline}

[Liver 9.6E-01 3.6E+00]{.underline}

[Lungs 2.5E+00 9.3E+00]{.underline}

[Muscle 3.9E-01 1.4E+00]{.underline}

[Ovaries 4.2E-01 1.5E+00]{.underline}

[Pancreas 5.5E-01 2.0E+00]{.underline}

[Red Marrow 4.9E-01 1.8E+00]{.underline}

[Bone Surfaces 4.4E-01 1.6E+00]{.underline}

[Skin 3.2E-01 1.2E+00]{.underline}

[Spleen 2.4E+00 9.0E+00]{.underline}

[Testes 3.5E-01 1.3E+00]{.underline}

[Thymus 5.6E-01 2.1E+00]{.underline}

[Thyroid 4.0E-01 1.5E+00]{.underline}

[Urinary Bladder Wall 5.2E-01 1.9E+00]{.underline}

[Uterus 4.2E-01 1.6E+00]{.underline}

[Effective Dose Equivalent 1.1E+00 mSv/MBq 4.0E+00 rem/mCi]{.underline}

[Based on total body kinetic model in ICRP 53 (data gathered in human
subjects), modified by assumed fractional distribution of blood in model
of Hui and Poston.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-131 MAA]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.8E-01 6.7E-01]{.underline}

[Brain 2.2E-02 8.2E-02]{.underline}

[Breasts 8.3E-02 3.1E-01]{.underline}

[Gallbladder Wall 2.5E-01 9.4E-01]{.underline}

[LLI Wall 3.8E-02 1.4E-01]{.underline}

[Small Intestine 6.1E-02 2.2E-01]{.underline}

[Stomach 8.4E-02 3.1E-01]{.underline}

[ULI Wall 7.8E-02 2.9E-01]{.underline}

[Heart Wall 1.6E-01 5.9E-01]{.underline}

[Kidneys 1.4E-01 5.3E-01]{.underline}

[Liver 2.0E+00 7.5E+00]{.underline}

[Lungs 2.3E+00 8.5E+00]{.underline}

[Muscle 6.0E-02 2.2E-01]{.underline}

[Ovaries 4.4E-02 1.6E-01]{.underline}

[Pancreas 1.5E-01 5.6E-01]{.underline}

[Red Marrow 7.3E-02 2.7E-01]{.underline}

[Bone Surfaces 6.3E-02 2.3E-01]{.underline}

[Skin 3.8E-02 1.4E-01]{.underline}

[Spleen 7.3E-02 2.7E-01]{.underline}

[Testes 2.7E-02 1.0E-01]{.underline}

[Thymus 9.0E-02 3.3E-01]{.underline}

[Thyroid 4.1E-02 1.5E-01]{.underline}

[Urinary Bladder Wall 4.9E-01 1.8E+00]{.underline}

[Uterus 5.2E-02 1.9E-01]{.underline}

[Effective Dose Equivalent 5.0E-01 mSv/MBq 1.8E+00 rem/mCi]{.underline}

[Model in ICRP 53 is adopted (data gathered in human subjects). Assumed
distribution and retention:]{.underline}

[ Lungs 85% T]{.underline}~[b]{.underline}~[ = 6 hr 15%
T]{.underline}~[b]{.underline}~[ = 72 hr]{.underline}

[ Liver 25% uptake T]{.underline}~[b]{.underline}~[ = 6 hr, elimination
T]{.underline}~[b]{.underline}~[ = 120 hr]{.underline}

[ Kidneys residence time = 0.108 hr]{.underline}

[Urinary bladder receives clearance from liver and long term clearance
from lung. Bladder voiding interval 4.8 hours.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-131 mIBG (i.v. injection) ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 2.1E-01 7.6E-01]{.underline}

[Brain 4.7E-02 1.7E-01]{.underline}

[Breasts 5.4E-02 2.0E-01]{.underline}

[Gallbladder Wall 1.4E-01 5.2E-01]{.underline}

[LLI Wall 7.2E-02 2.7E-01]{.underline}

[Small Intestine 7.5E-02 2.8E-01]{.underline}

[Stomach 7.8E-02 2.9E-01]{.underline}

[ULI Wall 7.9E-02 2.9E-01]{.underline}

[Heart Wall 3.8E-01 1.4E+00]{.underline}

[Kidneys 8.8E-02 3.3E-01]{.underline}

[Liver 7.8E-01 2.9E+00]{.underline}

[Lungs 7.4E-02 2.7E-01]{.underline}

[Muscle 6.2E-02 2.3E-01]{.underline}

[Ovaries 7.4E-02 2.7E-01]{.underline}

[Pancreas 1.1E-01 3.9E-01]{.underline}

[Red Marrow 7.4E-02 2.7E-01]{.underline}

[Bone Surfaces 6.5E-02 2.4E-01]{.underline}

[Salivary glands 2.4E-01 8.8E-01]{.underline}

[Skin 4.8E-02 1.8E-01]{.underline}

[Spleen 5.8E-01 2.2E+00]{.underline}

[Testes 5.8E-02 2.2E-01]{.underline}

[Thymus 6.4E-02 2.4E-01]{.underline}

[Thyroid 9.0E-02 3.3E-01]{.underline}

[Urinary Bladder Wall 7.6E-01 2.8E+00]{.underline}

[Uterus 8.9E-02 3.3E-01]{.underline}

[Effective Dose Equivalent 2.1E-01 mSv/MBq 7.8E-01 rem/mCi]{.underline}

[Based on data gathered in patients - Jacobsson et al, 4th International
Radiopharmaceutical Dosimetry Symposium, CONF-851113, pp. 389-398.
Assumed distribution and retention:]{.underline}

[Total body 63% T]{.underline}~[b]{.underline}~[ = 32.8 hours 36%
T]{.underline}~[b]{.underline}~[ = 3.05 hours 1%
T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Liver 21% T]{.underline}~[b]{.underline}~[ = 32.8 hours 15%
T]{.underline}~[b]{.underline}~[ = 3.05 hours 0.3%
T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[Spleen 0.6% T]{.underline}~[b]{.underline}~[ = 178 hours]{.underline}

[Sal. glands 0.04% T]{.underline}~[b]{.underline}~[ = 32.8
hours]{.underline}

[Thyroid 0.005% T]{.underline}~[b]{.underline}~[ = 168
hours]{.underline}

[Adrenals 0.02% T]{.underline}~[b]{.underline}~[ = 48.6
hours]{.underline}

[Heart wall 0.8% T]{.underline}~[b]{.underline}~[ = 120
hours]{.underline}

[Dynamic Bladder Model used (4.80 hour void) ]{.underline}

[ 36 % T]{.underline}~[b]{.underline}~[ = 3.00 hours 63 %
T]{.underline}~[b]{.underline}~[ = 33.6 hours]{.underline}

[Dose to salivary glands is self-dose only, based on 77 g mass and
photon absorbed]{.underline}

    fractions from MIRD Pamphlet No. 8.  Salivary gland activity did not contribute to other organ doses. Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)

    The effective dose equivalent is a quantity which may be suitable for comparing risks of different procedures in nuclear medicine, radiology, and other applications involving ionizing radiation, but should not be construed to give information to individual patients.

    Source: Radiation Internal Dose

            Information Center

    	September 18, 1992

[ Radiation Dose Estimates for I-131 Rose Bengal]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.0E-02 1.1E-01]{.underline}

[Brain 5.4E-04 2.0E-03]{.underline}

[Breasts 5.2E-03 1.9E-02]{.underline}

[Gallbladder Wall 6.6E-01 2.5E+00]{.underline}

[LLI Wall 8.4E+00 3.1E+01]{.underline}

[Small Intestine 8.2E-01 3.0E+00]{.underline}

[Stomach 7.2E-02 2.7E-01]{.underline}

[ULI Wall 3.2E+00 1.2E+01]{.underline}

[Heart Wall 1.2E-02 4.6E-02]{.underline}

[Kidneys 5.8E-02 2.1E-01]{.underline}

[Liver 1.9E-01 7.1E-01]{.underline}

[Lungs 9.6E-03 3.6E-02]{.underline}

[Muscle 4.4E-02 1.6E-01]{.underline}

[Ovaries 3.7E-01 1.4E+00]{.underline}

[Pancreas 4.5E-02 1.7E-01]{.underline}

[Red Marrow 7.1E-02 2.6E-01]{.underline}

[Bone Surfaces 3.6E-02 1.4E-01]{.underline}

[Skin 1.5E-02 5.6E-02]{.underline}

[Spleen 3.1E-02 1.1E-01]{.underline}

[Testes 3.7E-02 1.4E-01]{.underline}

[Thymus 4.2E-03 1.5E-02]{.underline}

[Thyroid 1.2E-03 4.6E-03]{.underline}

[Urinary Bladder Wall 1.7E-01 6.3E-01]{.underline}

[Uterus 1.7E-01 6.4E-01]{.underline}

[Effective Dose Equivalent 9.0E-01 mSv/MBq 3.3E+00 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 7 (data gathered in
human subjects), J Nucl Med 16:1214-1217, 1975.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information to individual patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for I-131 Sodium Iodide]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.9E-02 1.4E-01]{.underline}

[Brain 1.1E-01 4.1E-01]{.underline}

[Breasts 4.2E-02 1.6E-01]{.underline}

[Gallbladder Wall 4.5E-02 1.7E-01]{.underline}

[LLI Wall 4.3E-02 1.6E-01]{.underline}

[Small Intestine 2.4E-01 8.8E-01]{.underline}

[Stomach 3.6E-01 1.3E+00]{.underline}

[ULI Wall 5.2E-02 1.9E-01]{.underline}

[Heart Wall 5.7E-02 2.1E-01]{.underline}

[Kidneys 3.6E-02 1.3E-01]{.underline}

[Liver 1.1E-01 3.9E-01]{.underline}

[Lungs 7.9E-02 2.9E-01]{.underline}

[Muscle 1.0E-01 3.7E-01]{.underline}

[Ovaries 4.7E-02 1.8E-01]{.underline}

[Pancreas 5.2E-02 1.9E-01]{.underline}

[Red Marrow 8.3E-02 3.1E-01]{.underline}

[Bone Surfaces 1.0E-01 3.7E-01]{.underline}

[Skin 5.1E-02 1.9E-01]{.underline}

[Spleen 4.1E-02 1.5E-01]{.underline}

[Testes 2.8E-02 1.0E-01]{.underline}

[Thymus 1.2E-01 4.4E-01]{.underline}

[Thyroid 3.4E+02 1.3E+03]{.underline}

[Urinary Bladder Wall 6.2E-01 2.3E+00]{.underline}

[Uterus 5.9E-02 2.2E-01]{.underline}

[Effective Dose Equivalent 1.1E+01 mSv/MBq 3.9E+01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 5 (data gathered in
human subjects), J Nucl Med 16:857-860, 1975 (25% thyroid
uptake).]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity for which may be suitable
for comparing risks of different procedures in nuclear medicine,
radiology, and other applications involving ionizing radiation, but
should not be construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

[April 12, 1996]{.underline}

[Radiation Dose Estimates for I-131 Sodium Iodide]{.underline}

[In the Reference Adult - Athyroid Patient\*]{.underline}

[Estimated Radiation Dose]{.underline}

[ORGAN mGy rad]{.underline}

[ MBq mCi]{.underline}

[Adrenals 2.3E-02 8.4E-02]{.underline}

[Brain 1.1E-02 4.0E-02]{.underline}

[Breast 1.2E-02 4.5E-02]{.underline}

[Gallbladder Wall 3.3E-02 1.2E-01]{.underline}

[LLI Wall 3.7E-02 1.4E-01]{.underline}

[Small Intestine 2.3E-01 8.6E-01]{.underline}

[Stomach 3.5E-01 1.3E+00]{.underline}

[ULI Wall 4.2E-02 1.6E-01]{.underline}

[Heart Wall 1.9E-02 6.9E-02]{.underline}

[Kidneys 2.3E-02 8.4E-02]{.underline}

[Liver 9.6E-02 3.6E-01]{.underline}

[Lungs 1.5E-02 5.7E-02]{.underline}

[Muscle 1.9E-02 6.9E-02]{.underline}

[Ovaries 4.0E-02 1.5E-01]{.underline}

[Pancreas 3.6E-02 1.3E-01]{.underline}

[Red Marrow 1.9E-02 7.1E-02]{.underline}

[Bone Surfaces 1.8E-02 6.6E-02]{.underline}

[Skin 1.3E-02 4.6E-02]{.underline}

[Spleen 2.5E-02 9.3E-02]{.underline}

[Testes 2.1E-02 7.9E-02]{.underline}

[Thymus 1.4E-02 5.0E-02]{.underline}

[Urinary Bladder Wall 8.1E-01 3.0E+00]{.underline}

[Uterus 5.6E-02 2.1E-01]{.underline}

[Total Body 2.4E-02 8.8E-02]{.underline}

[Effective Dose Equivalent 1.1E-01 mSv/MBq 4.0E-01 rem/mCi]{.underline}

[\* Model in MIRD Dose Estimate Report No. 5 (J Nucl Med 16:857-860,
1975) used, except total body clearance assumed to be 100%,
T]{.underline}~[b]{.underline}~[ = 6 hr. Assumed residence
times:]{.underline}

[Small Intestine 1.50E+00 hr]{.underline}

[Stomach 1.33E+00 hr]{.underline}

[Liver 1.16E+00 hr]{.underline}

[Urinary Bladder Contents 2.53E+00 hr]{.underline}

[Remainder 4.40E+00 hr]{.underline}

[Estimate calculated using phantoms of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke-Stelson and E.E. Watson eds.
CONF-851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. Pp 514-534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risks to individual patients and
should not be applied to situations involving radiation
therapy.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

[ ]{.underline}`	``September 18, 1992`

[ Radiation Dose Estimates for Inhalation of Xe-127 ]{.underline}

[ (Breathhold)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.3E-4 4.6E-4]{.underline}

[Brain 8.3E-5 3.1E-4]{.underline}

[Breasts 8.5E-5 3.2E-4]{.underline}

[Gallbladder Wall 1.2E-4 4.4E-4]{.underline}

[LLI Wall 1.1E-4 4.2E-4]{.underline}

[Small Intestine 1.2E-4 4.3E-4]{.underline}

[Stomach 1.1E-4 4.2E-4]{.underline}

[ULI Wall 1.1E-4 4.2E-4]{.underline}

[Heart Wall 1.4E-4 5.0E-4]{.underline}

[Kidneys 1.1E-4 3.9E-4]{.underline}

[Liver 1.2E-4 4.3E-4]{.underline}

[Lungs 3.6E-4 1.3E-3]{.underline}

[Muscle 9.5E-5 3.5E-4]{.underline}

[Ovaries 1.2E-4 4.4E-4]{.underline}

[Pancreas 1.3E-4 4.7E-4]{.underline}

[Red Marrow 1.0E-4 3.9E-4]{.underline}

[Bone Surfaces 1.5E-4 5.7E-4]{.underline}

[Skin 6.5E-5 2.4E-4]{.underline}

[Spleen 1.1E-4 4.2E-4]{.underline}

[Testes 8.7E-5 3.2E-4]{.underline}

[Thymus 1.1E-4 4.2E-4]{.underline}

[Thyroid 1.0E-4 3.8E-4]{.underline}

[Urinary Bladder Wall 1.1E-4 4.1E-4]{.underline}

[Uterus 1.2E-4 4.4E-4]{.underline}

[Effective Dose Equivalent 1.4E-4 mSv/MBq 5.3E-04 rem/Ci]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information to individual patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Inhalation of Xe-127 ]{.underline}

[ (5 minute rebreathing)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 7.8E-04 2.9E-03]{.underline}

[Brain 5.9E-04 2.2E-03]{.underline}

[Breasts 5.0E-04 1.8E-03]{.underline}

[Gallbladder Wall 8.2E-04 3.0E-03]{.underline}

[LLI Wall 8.0E-04 3.0E-03]{.underline}

[Small Intestine 8.2E-04 3.0E-03]{.underline}

[Stomach 7.5E-04 2.8E-03]{.underline}

[ULI Wall 7.9E-04 2.9E-03]{.underline}

[Heart Wall 7.6E-04 2.8E-03]{.underline}

[Kidneys 7.2E-04 2.7E-03]{.underline}

[Liver 7.4E-04 2.7E-03]{.underline}

[Lungs 8.2E-04 3.0E-03]{.underline}

[Muscle 6.3E-04 2.3E-03]{.underline}

[Ovaries 8.3E-04 3.1E-03]{.underline}

[Pancreas 8.3E-04 3.1E-03]{.underline}

[Red Marrow 6.9E-04 2.6E-03]{.underline}

[Bone Surfaces 1.0E-04 3.8E-03]{.underline}

[Skin 4.4E-04 1.6E-03]{.underline}

[Spleen 7.3E-04 2.7E-03]{.underline}

[Testes 6.2E-04 2.3E-03]{.underline}

[Thymus 6.9E-04 2.5E-03]{.underline}

[Thyroid 6.9E-04 2.5E-03]{.underline}

[Urinary Bladder Wall 7.8E-04 2.9E-03]{.underline}

[Uterus 8.4E-04 3.1E-03]{.underline}

[Effective Dose Equivalent 7.6E-04mSv/MBq 2.8E-03rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
constured to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Inhalation of Xe-127 ]{.underline}

[ (10 minute rebreathing)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.3E-03 4.7E-03]{.underline}

[Brain 9.5E-04 3.5E-03]{.underline}

[Breasts 7.9E-04 2.9E-03]{.underline}

[Gallbladder Wall 1.3E-03 4.9E-03]{.underline}

[LLI Wall 1.3E-03 4.8E-03]{.underline}

[Small Intestine 1.3E-03 4.9E-03]{.underline}

[Stomach 1.2E-03 4.5E-03]{.underline}

[ULI Wall 1.3E-03 4.7E-03]{.underline}

[Heart Wall 1.2E-03 4.5E-03]{.underline}

[Kidneys 1.2E-03 4.3E-03]{.underline}

[Liver 1.2E-03 4.4E-03]{.underline}

[Lungs 1.1E-03 4.0E-03]{.underline}

[Muscle 1.0E-03 3.7E-03]{.underline}

[Ovaries 1.4E-03 5.0E-03]{.underline}

[Pancreas 1.3E-03 5.0E-03]{.underline}

[Red Marrow 1.1E-03 4.1E-03]{.underline}

[Bone Surfaces 1.6E-03 6.1E-03]{.underline}

[Skin 7.1E-04 2.6E-03]{.underline}

[Spleen 1.2E-03 4.4E-03]{.underline}

[Testes 1.0E-03 3.7E-03]{.underline}

[Thymus 1.1E-03 4.1E-03]{.underline}

[Thyroid 1.1E-03 4.1E-03]{.underline}

[Urinary Bladder Wall 1.3E-03 4.7E-03]{.underline}

[Uterus 1.4E-03 5.0E-03]{.underline}

[Effective Dose Equivalent 1.2E-03 mSv/MBq 4.4E-03 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Inhalation of Xe-133]{.underline}

[ (Breathhold)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.0E-04 3.8E-04]{.underline}

[Brain 9.7E-05 3.6E-04]{.underline}

[Breasts 9.5E-05 3.5E-04]{.underline}

[Gallbladder Wall 1.0E-04 3.8E-04]{.underline}

[LLI Wall 1.0E-04 3.7E-04]{.underline}

[Small Intestine 1.0E-04 3.7E-04]{.underline}

[Stomach 1.0E-04 3.7E-04]{.underline}

[ULI Wall 1.0E-04 3.7E-04]{.underline}

[Heart Wall 1.1E-04 3.9E-04]{.underline}

[Kidneys 9.8E-05 3.6E-04]{.underline}

[Liver 1.0E-04 3.8E-04]{.underline}

[Lungs 8.2E-04 3.0E-03]{.underline}

[Muscle 9.7E-04 3.6E-04]{.underline}

[Ovaries 1.0E-04 3.7E-04]{.underline}

[Pancreas 1.0E-04 3.8E-04]{.underline}

[Red Marrow 1.2E-04 4.4E-04]{.underline}

[Bone Surfaces 1.2E-04 4.5E-04]{.underline}

[Skin 9.0E-05 3.3E-04]{.underline}

[Spleen 1.0E-04 3.7E-04]{.underline}

[Testes 9.5E-05 3.5E-04]{.underline}

[Thymus 1.0E-04 3.7E-04]{.underline}

[Thyroid 9.9E-05 3.7E-04]{.underline}

[Urinary Bladder Wall 1.0E-04 3.7E-04]{.underline}

[Uterus 1.0E-04 3.7E-04]{.underline}

[Effective Dose Equivalent 1.9E-04 mSv/MBq 7.1E-04 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Inhalation of Xe-133]{.underline}

[ (5 minute rebreathing)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 6.9E-04 2.6E-03]{.underline}

[Brain 6.7E-04 2.5E-03]{.underline}

[Breasts 6.4E-04 2.4E-03]{.underline}

[Gallbladder Wall 7.0E-04 2.6E-03]{.underline}

[LLI Wall 7.0E-04 2.6E-03]{.underline}

[Small Intestine 7.0E-04 2.6E-03]{.underline}

[Stomach 6.9E-04 2.5E-03]{.underline}

[ULI Wall 6.9E-04 2.6E-03]{.underline}

[Heart Wall 6.9E-04 2.6E-03]{.underline}

[Kidneys 6.8E-04 2.5E-03]{.underline}

[Liver 6.9E-04 2.5E-03]{.underline}

[Lungs 1.1E-03 4.2E-03]{.underline}

[Muscle 6.6E-04 2.5E-03]{.underline}

[Ovaries 7.0E-04 2.6E-03]{.underline}

[Pancreas 7.1E-04 2.6E-03]{.underline}

[Red Marrow 8.3E-04 3.1E-03]{.underline}

[Bone Surfaces 8.2E-04 3.0E-03]{.underline}

[Skin 6.2E-04 2.3E-03]{.underline}

[Spleen 6.9E-04 2.5E-03]{.underline}

[Testes 6.6E-04 2.4E-03]{.underline}

[Thymus 6.8E-04 2.5E-03]{.underline}

[Thyroid 6.8E-04 2.5E-03]{.underline}

[Urinary Bladder Wall 6.9E-04 2.6E-03]{.underline}

[Uterus 7.1E-04 2.6E-03]{.underline}

[Effective Dose Equivalent 7.6E-04 mSv/MBq 2.8E-03 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information to individual patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Inhalation of Xe-133]{.underline}

[ (10 minute rebreathing)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 1.2E-03 4.3E-03]{.underline}

[Brain 1.1E-03 4.1E-03]{.underline}

[Breasts 1.1E-03 3.9E-03]{.underline}

[Gallbladder Wall 1.2E-03 4.3E-03]{.underline}

[LLI Wall 1.2E-03 4.3E-03]{.underline}

[Small Intestine 1.2E-03 4.3E-03]{.underline}

[Stomach 1.1E-03 4.2E-03]{.underline}

[ULI Wall 1.2E-03 4.3E-03]{.underline}

[Heart Wall 1.1E-03 4.2E-03]{.underline}

[Kidneys 1.1E-03 4.2E-03]{.underline}

[Liver 1.1E-03 4.2E-03]{.underline}

[Lungs 1.2E-03 4.4E-03]{.underline}

[Muscle 1.1E-03 4.1E-03]{.underline}

[Ovaries 1.2E-03 4.3E-03]{.underline}

[Pancreas 1.2E-03 4.3E-03]{.underline}

[Red Marrow 1.4E-03 5.1E-03]{.underline}

[Bone Surfaces 1.4E-03 5.0E-03]{.underline}

[Skin 1.0E-03 3.8E-03]{.underline}

[Spleen 1.1E-03 4.2E-03]{.underline}

[Testes 1.1E-03 4.0E-03]{.underline}

[Thymus 1.1E-03 4.1E-03]{.underline}

[Thyroid 1.1E-03 4.2E-03]{.underline}

[Urinary Bladder Wall 1.1E-03 4.2E-03]{.underline}

[Uterus 1.2E-03 4.3E-03]{.underline}

[Effective Dose Equivalent 1.2E-03 mSv/MBq 4.4E-03 rem/mCi]{.underline}

[Based on the model in MIRD Dose Estimate Report No. 9 (data gathered in
human subjects), J Nucl Med 21:459-465, 1980.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	September 18, 1992

[ Radiation Dose Estimates for Xe-133 Injections ]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 3.8E-05 1.4E-04]{.underline}

[Brain 3.8E-06 1.4E-05]{.underline}

[Breasts 4.2E-05 1.5E-04]{.underline}

[Gallbladder Wall 1.2E-05 4.4E-05]{.underline}

[LLI Wall 3.7E-06 1.4E-05]{.underline}

[Small Intestine 4.5E-06 1.7E-05]{.underline}

[Stomach 2.2E-05 8.0E-05]{.underline}

[ULI Wall 4.8E-06 1.8E-05]{.underline}

[Heart Wall 1.8E-03 6.5E-03]{.underline}

[Kidneys 1.0E-05 3.8E-05]{.underline}

[Liver 3.9E-05 1.4E-04]{.underline}

[Lungs 7.1E-03 2.6E-02]{.underline}

[Muscle 2.1E-05 7.7E-05]{.underline}

[Ovaries 3.7E-06 1.4E-05]{.underline}

[Pancreas 3.0E-05 1.1E-04]{.underline}

[Red Marrow 1.9E-05 7.0E-05]{.underline}

[Bone Surfaces 4.3E-05 1.6E-04]{.underline}

[Skin 8.6E-06 3.2E-05]{.underline}

[Spleen 2.9E-05 1.1E-04]{.underline}

[Testes 3.2E-06 1.2E-05]{.underline}

[Thymus 6.8E-05 2.5E-04]{.underline}

[Thyroid 1.2E-05 4.6E-05]{.underline}

[Urinary Bladder Wall 3.5E-06 1.3E-05]{.underline}

[Uterus 3.7E-06 1.4E-05]{.underline}

[Effective Dose Equivalent 9.9E-04 mSv/MBq 3.6E-03 rem/mCi]{.underline}

[Residence times based on a model in which activity clears from the
blood,]{.underline}

[to the right heart, lungs, left heart, and back to blood, with 95%
clearance]{.underline}

[of blood from lungs on each pass. Half times for transport are 1 minute
in]{.underline}

[heart chambers, 5 minutes in lung, and 3 minutes in the body. (No human
or animal data used.)]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 27, 1995

[ Radiation Dose Estimates for Hg-197 Chlormerodrin]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.1E-02 1.5E-01 ]{.underline}

[Brain 2.8E-03 1.0E-02 ]{.underline}

[Breasts 4.1E-03 1.5E-02 ]{.underline}

[Gallbladder Wall 4.4E-02 1.6E-01 ]{.underline}

[LLI Wall 6.1E-03 2.2E-02 ]{.underline}

[Small Intestine 1.3E-02 4.7E-02 ]{.underline}

[Stomach 1.4E-02 5.3E-02 ]{.underline}

[ULI Wall 1.4E-02 5.4E-02 ]{.underline}

[Heart Wall 1.1E-02 4.1E-02 ]{.underline}

[Kidneys 2.2E+00 8.1E+00 ]{.underline}

[Liver 3.5E-01 1.3E+00 ]{.underline}

[Lungs 1.1E-02 4.1E-02 ]{.underline}

[Muscle 1.1E-02 4.1E-02 ]{.underline}

[Ovaries 9.3E-03 3.4E-02 ]{.underline}

[Pancreas 3.1E-02 1.1E-01 ]{.underline}

[Red Marrow 2.3E-02 8.4E-02 ]{.underline}

[Bone Surfaces 2.7E-01 9.8E-01 ]{.underline}

[Skin 4.2E-03 1.6E-02 ]{.underline}

[Spleen 2.8E-02 1.0E-01 ]{.underline}

[Testes 6.0E-03 2.2E-02 ]{.underline}

[Thymus 4.2E-03 1.6E-02 ]{.underline}

[Thyroid 3.0E-03 1.1E-02 ]{.underline}

[Urinary Bladder Wall 1.3E-01 4.9E-01 ]{.underline}

[Uterus 8.6E-03 3.2E-02 ]{.underline}

[Effective Dose Equivalent 1.8E-01 mSv/MBq 6.7E-01 rem/mCi]{.underline}

[Based on model in MIRD Dose Estimate Report No. 6 (data gathered in
human subjects). Dynamic bladder model with 4.8-hour voiding
interval]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	

                                February 27, 1995

[ Radiation Dose Estimates for Au-198 Colloid]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 4.1E-01 1.5E+00 ]{.underline}

[Brain 4.5E-02 1.7E-01 ]{.underline}

[Breasts 9.9E-02 3.7E-01 ]{.underline}

[Gallbladder Wall 6.4E-01 2.4E+00 ]{.underline}

[LLI Wall 7.7E-02 2.9E-01 ]{.underline}

[Small Intestine 1.5E-01 5.5E-01 ]{.underline}

[Stomach 2.2E-01 8.3E-01 ]{.underline}

[ULI Wall 1.9E-01 7.1E-01 ]{.underline}

[Heart Wall 2.2E-01 8.2E-01 ]{.underline}

[Kidneys 3.2E-01 1.2E+00 ]{.underline}

[Liver 7.8E+00 2.9E+01 ]{.underline}

[Lungs 2.0E-01 7.3E-01 ]{.underline}

[Muscle 1.1E-01 4.1E-01 ]{.underline}

[Ovaries 9.5E-02 3.5E-01 ]{.underline}

[Pancreas 4.3E-01 1.6E+00 ]{.underline}

[Red Marrow 8.8E-01 3.3E+00 ]{.underline}

[Bone Surfaces 5.5E-01 2.0E+00 ]{.underline}

[Skin 7.1E-02 2.6E-01 ]{.underline}

[Spleen 1.1E+01 3.9E+01 ]{.underline}

[Testes 4.2E-02 1.6E-01 ]{.underline}

[Thymus 9.3E-02 3.4E-01 ]{.underline}

[Thyroid 5.5E-02 2.0E-01 ]{.underline}

[Urinary Bladder Wall 6.2E-02 2.3E-01 ]{.underline}

[Uterus 8.4E-02 3.1E-01 ]{.underline}

[Effective Dose Equivalent 1.4E+00 mSv/MBq 5.1E+00 rem/mCi]{.underline}

[Based on model in ICRP 53 (data gathered in human subjects). Liver
receives 70%, spleen 10%, marrow and remainder receive 15% each, all
with T]{.underline}~[b]{.underline}~[ = ¥.]{.underline}

[Dynamic bladder model with 4.8-hour voiding interval.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of
dosimetry of radionuclides within the skeleton with particular emphasis
on the active marrow, In Fourth International Radiopharmaceutical
Dosimetry Symposium; A.T. Schlafke‑Stelson and E. E. Watson eds.
CONF‑851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831,
1986. pp 514‑534.) used.]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information about risk to individual
patients.]{.underline}

[Source: Radiation Internal Dose]{.underline}

[ Information Center]{.underline}

    	February 15, 1995

[ Radiation Dose Estimates for Tl-201 Chloride (plus
contaminants)]{.underline}

[ Estimated Radiation Dose]{.underline}

[ mGy rad ]{.underline}

[ORGAN MBq mCi ]{.underline}

[Adrenals 6.3E-02 2.3E-01]{.underline}

[Brain 5.9E-02 2.2E-01]{.underline}

[Breasts 3.6E-02 1.3E-01]{.underline}

[GB Wall 8.3E-02 3.1E-01]{.underline}

[LLI Wall 3.4E-01 1.2E+00]{.underline}

[Small Intestine 4.5E-01 1.7E+00]{.underline}

[Stomach 1.9E-01 6.9E-01]{.underline}

[ULI Wall 3.3E-01 1.2E+00]{.underline}

[Heart Wall 2.8E-01 1.0E+00]{.underline}

[Kidneys 4.6E-01 1.7E+00]{.underline}

[Liver 9.9E-02 3.7E-01]{.underline}

[Lungs 4.7E-02 1.7E-01]{.underline}

[Muscle 4.6E-02 1.7E-01]{.underline}

[Ovaries 1.0E-01 3.7E-01]{.underline}

[Pancreas 7.4E-02 2.7E-01]{.underline}

[Red Marrow 5.5E-02 2.0E-01]{.underline}

[Bone Surfaces 8.8E-02 3.3E-01]{.underline}

[Skin 3.3E-02 1.2E-01]{.underline}

[Spleen 1.8E-01 6.5E-01]{.underline}

[Testes 2.0E-01 7.3E-01 ]{.underline}

[Thymus 4.6E-02 1.7E-01]{.underline}

[Thyroid 6.2E-01 2.3E+00]{.underline}

[Urinary Bladder Wall 5.2E-02 1.9E-01]{.underline}

[Uterus 8.5E-02 3.1E-01]{.underline}

[Effective Dose Equivalent 1.6E-01 mSv/MBq 6.0E-01 rem/mCi]{.underline}

[Based on data gathered in humans by Krahwinkel et al. (J Nucl Med
29(9):1582-1586, 1988) and data on testicular uptake and clearance
gathered in humans by Thomas et al. (personal communication, 1994).
Assumed distribution and retention:]{.underline}

[Brain 1.76% T]{.underline}~[b]{.underline}~[ = ¥]{.underline}

[LLI 3.6% T]{.underline}~[b]{.underline}~[ = 191 hr (Activity in
wall)]{.underline}

[Small Int 14.4% T]{.underline}~[b]{.underline}~[ = 191 hr (Activity in
wall)]{.underline}

[Stomach 2.8% T]{.underline}~[b]{.underline}~[ = 205 hr (Activity in
wall)]{.underline}

[ULI 4.7% T]{.underline}~[b]{.underline}~[ = 191 hr (Activity in
wall)]{.underline}

[Heart Wall 3.4% T]{.underline}~[b]{.underline}~[ = 179 hr ]{.underline}

[Kidneys 4.5% T]{.underline}~[b]{.underline}~[ = 260 hr 0.97%
T]{.underline}~[b]{.underline}~[ = 27 hr]{.underline}

[Liver 4.6% T]{.underline}~[b]{.underline}~[ = 218 hr ]{.underline}

[Spleen 0.74% T]{.underline}~[b]{.underline}~[ = 640 hr 0.28%
T]{.underline}~[b]{.underline}~[ = 37 hr]{.underline}

[Testes residence time 0.26 hr]{.underline}

[Thyroid 0.29% T]{.underline}~[b]{.underline}~[ = 350 hr 0.24%
T]{.underline}~[b]{.underline}~[ = 166 hr]{.underline}

[Total Body 31% T]{.underline}~[b]{.underline}~[ = 146 hr 69%
T]{.underline}~[b]{.underline}~[ = 502 hr]{.underline}

[Urinary Bladder Clearance: 6.2% T]{.underline}~[b]{.underline}~[ = 146
hr, 13.8% T]{.underline}~[b]{.underline}~[ = 502 hr]{.underline}

[Bladder voiding interval 4.8 hr. Contaminants assumed: Tl-200 (1%),
Tl-202]{.underline}

[(0.33%), Pb-201(0.33%), Pb-203(0.33%). Includes dose from Tl-201 Auger
electrons.]{.underline}

[Estimate calculated using phantom of Cristy & Eckerman (Report
ORNL/TM-8381/V1 & V7)]{.underline}

[The effective dose equivalent is a quantity which may be suitable for
comparing risks of different procedures in nuclear medicine, radiology,
and other applications involving ionizing radiation, but should not be
construed to give information to individual patients.]{.underline}

    Source: Radiation Internal Dose

            Information Center