# Presentation: 667709

## AIPL Contributions to S-1008

## Stillbirth Genetic CorrelationsService sire SB above diagonal, daughter SB below

| Ctry | DNK | FIN | ISR | NLD | SWE | USA |
| --- | --- | --- | --- | --- | --- | --- |
| DNK |  | .85 | .82 | .67 | .92 | .70 |
| FIN | .82 |  | .77 | .64 | .82 | .65 |
| ISR | .67 | .70 |  | .73 | .80 | .66 |
| NLD | .82 | .77 | .60 |  | .65 | .63 |
| SWE | .88 | .92 | .65 | .73 |  | .64 |
| USA | .81 | .87 | .60 | .71 | .87 |  |

## Calving Ease Genetic CorrelationsService sire CE above diagonal, daughter CE below

| Ctry | CAN | DNK | FRA | ITA | NLD | SWE | USA |
| --- | --- | --- | --- | --- | --- | --- | --- |
| CAN |  | .87 | .81 | .70 | .80 | .86 | .75 |
| DNK | .84 |  | .93 | .77 | .86 | .96 | .90 |
| FRA | .80 | .80 |  | .74 | .84 | .91 | .88 |
| ITA | .58 | .59 | .85 |  | .60 | .70 | .61 |
| NLD | .89 | .81 | .79 | .59 |  | .89 | .79 |
| SWE | .75 | .82 | .89 | .78 | .69 |  | .86 |
| USA | .71 | .78 | .93 | .76 | .77 | .87 |  |

## Brown Swiss Calving Ease Service sire correlations above diagonal, daughter below

| Ctry | CHE | DEU | NLD | USA |
| --- | --- | --- | --- | --- |
| CHE |  | .83 | .81 | .68 |
| DEU | .61 |  | .77 | .67 |
| NLD | .89 | .76 |  | .79 |
| USA | .70 | .61 | .76 |  |

## Milk (kg)Genetic trend on all-breed base

## Fat (kg)Genetic trend on all-breed base

## Protein (kg)Genetic trend on all-breed base

## Somatic Cell ScoreGenetic trend on all-breed base

## Productive LifeGenetic trend on all-breed base

## Daughter Pregnancy RateGenetic trend on all-breed base

## Economic Measures, Cow Size1987 ADSA meeting

| Goal | Production | Body Size |
| --- | --- | --- |
| Profit / Cow | 6 | -1 |
| Profit / Investment | 5 | -1 |
| Feed Efficiency | 1.4 | -1 |
| Labor Efficiency | 1 | 0 |

## Possible Economic Measures

**Lifetime Profit or ANRI-OC**
**Discounted net present value**
**Annualized profit / annualized cost**
**Return on investment**
**Others?**

## Alleles Shared by Sibs

| Indep-endent Loci | Percentage of alleles shared |  |  |  |
| --- | --- | --- | --- | --- |
|  | Full sibs |  | Half sibs |  |
|  | Mean | SD | Mean | SD |
| 1 | 50 | 35.4 | 25 | 17.7 |
| 5 | 50 | 15.8 | 25 | 7.9 |
| 10 | 50 | 11.2 | 25 | 5.6 |
| 30 | 50 | 6.5 | 25 | 3.2 |
| 60 | 50 | 4.6 | 25 | 2.3 |
| Infinite | 50 | 0.0 | 25 | 0.0 |

## Reliability from SibsAssuming 60 loci affect trait

| 
Number of Sibs | Reliability Obtained From: |  |  |  |
| --- | --- | --- | --- | --- |
|  | Full sibs |  | Half sibs |  |
|  | A | G | A | G |
| 1 | .250 | .250 | .062 | .063 |
| 10 | .454 | .494 | .192 | .205 |
| 100 | .495 | .907 | .243 | .341 |
| Infinite | .500 | 1.000 | .250 | .500 |

**A**** = traditional additive relationships, ****G**** = genomic relationships**

## REL from Sibs of ParentsAssuming 60 independent loci affect trait

| Parents + Number of Sibs | Reliability Obtained From: |  |  |  |
| --- | --- | --- | --- | --- |
|  | Full sibs |  | Half sibs |  |
|  | A | G | A | G |
| 1 | .500 | .500 | .500 | .500 |
| 10 | .500 | .517 | .500 | .500 |
| 100 | .500 | .703 | .500 | .551 |
| Infinite | .500 | .750 | .500 | .625 |

**A**** = traditional additive relationships, ****G**** = genomic relationships**

## REL from Unrelated Animals

| 
Unrelated Animals | Loci Affecting Trait |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- |
|  | 100 |  | 1000 |  | 10,000 |  |
|  | A | G | A | G | A | G |
| 1 | .000 | .001 | .000 | .001 | .000 | .000 |
| 10 | .000 | .010 | .000 | .008 | .000 | .001 |
| 100 | .000 | .100 | .000 | .080 | .000 | .008 |
| 1000 | .000 | .969 | .000 | .610 | .000 | .079 |

**A**** = traditional additive relationships, ****G**** = genomic relationships**

## Genomic EBVs for Real Bulls

**USDA-BFGL study with industry funding using 60,000 SNPs**
**Genotype ~2000 proven bulls **
**Predict ~400 bulls sampled later**
**Reliability = 71% vs 36% from PA**
**Higher if LD & major loci assumed**

## Conclusions

**Corr (USA, foreign stillbirth) ~ .70**
**All-breed genetic trends seem reasonable**
**Several economic goals are possible**
**Dense maps will change selection**