# Presentation: 263340

## HOW DID WE GET HERE?

## MI/CCP Pilot Program(1999)

- MI/CCP Pilot Program(1999)

## P20

**P20**

- R25T
- T32
- K12

- RPG

- R25E

**MICCP**

**MICCP MECHANISMS** 	           **INDIVIDUAL OPTIONS**

- EDUCATION
- OUTREACH

- RESEARCH

- TRAINING

**U54**

**Notes:**

It is expected that the partnership will demonstrate a transition from planning to the specialized center and from pilot to full projects supported by the U54 mechanism.
However, what if this does not occur? Will we have thrown our money down the drain?
No, we believe that this model provides a win-win situation for us in that even if these planning projects don’t spawn into specialized cancer centers that some modicum of success will be seen with an increase in the number of grant applications in the traditional grant mechanisms which is also an immediate indicator of success as well.  For example for those collaborations in research we hope to see more R01/P01 type. applications from MSIs and CC se targeted areas  and so on.

Again, it is expected that staff will play a critical role in assuring that these partnerships, once funded, will lead to activities that will impact the cancer burden in minority populations.  THANK YOU.

## MI/CCP Program Structure

- MSI and Cancer Center

**P20**
- Planning Grant Collaborations

**U56**
**Cooperative Comprehensive Planning Grant**

**U54**
- Comprehensive Grant

- RO1, PO1, R25,
- T32, SPORES

- RO1, PO1, R25,
- T32, SPORES

## Slide 5

## WHERE WE ARE NOW

## Slide 7

## P20 Partnerships

| 
Columbia | 
LIU |
| --- | --- |
| AHF | Brooklyn |
| UCSF | SFSU |
| GT | UDC |
| UAB | Tuskegee |
| Moffitt | UPR |
| Wake Forest | Winston-Salem State |
| U. Colorado | Southern Colorado |
| Duke | North Caroline Central |
| Emory | Clark-Atlanta |
| Pittsburg | Hampton |
| U. South Carolina | Claflin |
| Rosewell Park | UPR-Rio Pedros |

## MI/CCP

**MI/CCP**
**P20 Planning Grants**

## U56 Partnerships

| Lineberger | North Carolina Central |
| --- | --- |
| UAB | Morehouse |
| MSKCC | CCNY |
| UCSD | SDSU |
| UCSF | SFSU |
| Fred Hutchingson | New Mexico State |
| Hawaii | Guam |
| UMD-Balitmore | UMD Eastern Shore |
| GT | UDC |
| UCLA | Drew |

## MI/CCP

**MI/CCP**
**U56 Planning Grants**

## U54 Partnerships

| Johns Hopkins | Howard Cancer Center |
| --- | --- |
| Vanderbilt | Meharry |
| MD Anderson | UPR |
| AZCC | Northern Arizona |
| Columbia | LIU |

## MI/CCP 

**MI/CCP **
**U54 Planning Grants**

## Slide 14

## Slide 15

## Slide 16

## Slide 17

## Slide 18

## Slide 19

## Current Cores/Resources 

**DNA micro-array and sequencing**
**Epi-Stat Core**
**Tissue Bank**
**PCR**
**Genomic/Proteomic**
**Genotyping**
**Molecular Biology**
**EM/NMR**

**Biostatistics**
**Clinical Investigators**
**Clinical Trial**
**Recruitment**
**Prevention**
**Training**
**Imaging/FACS**
**Bioethics**
**Websites**

## First yearOBSERVATIONS&RECOMMENDATIONS

## First Year Observations

- Demonstrate commitment to MI/CCP by ensuring:
- 		other resources and infrastructure support are regularly accessed by MI/CCP research, training, education and outreach activities.

## Slide 23

| NCMHD Centers of Excellence Program/FY 02 |  |  |
| --- | --- | --- |
| Tuskegee University | Tuskegee  | Alabama  |
| University of Alabama, Birmingham  | Birmingham  | Alabama  |
| Morehouse School of Medicine | Atlanta | Georgia  |
| Charles R. Drew University of Medicine and Science  | Los Angeles  | California  |
| San Diego State University  | San Diego | California  |
| University of California - Los Angeles  | Los Angeles  | California  |
| University of California - San Diego | La Jolla | California  |
| Howard University  | Washington | District of Columbia  |
| University of Hawaii at Manoa  | Honolulu | Hawaii  |
| Johns Hopkins University | Baltimore | Maryland  |
| North Carolina Central University  | Durham | North Carolina  |
| University of North Carolina | Chapel Hill  | North Carolina  |
| University of Pittsburgh  | Pittsburgh | Pennsylvania  |
| Hampton University  | Hampton | Virginia  |

## Slide 24

| NCMHD Centers of Excellence Program/FY 03 |  |  |
| --- | --- | --- |
| Institution | City | State |
| University of Alabama, Birmingham | Birmingham | Alabama  |
| University of Arizona | Tucson | Arizona  |
| University of California, Los Angeles | Los Angeles | California  |
| University of Colorado Health Sciences Center | Aurora | Colorado  |
| Howard University | Washington | District of Columbia  |
| University of Colorado Health Sciences Center | Aurora | Colorado  |
| Howard University | Washington | District of Columbia  |
| University of Maryland Baltimore Professional School | Baltimore | Maryland  |
| University of Puerto Rico Medical Sciences Campus | San Juan | Puerto Rico  |
| Meharry Medical College | Nashville | Tennessee  |
| University of Texas MD Anderson Cancer Center | Houston | Texas  |

## Slide 25

| RCMI |  |  |
| --- | --- | --- |
| Institution | City  | State |
| Tuskegee | Tuskegee | Alabama |
| Drew | L. A.  | California |
| Morehouse School of Medicine | Atlanta | Georgia |
| University Hawaii | Honolulu | Hawaii |
| CNNY | Manhattan  | New York |
| U. P.R. Medical | San Juan  | Puerto Rico |
| U. P. R. Rio Piedras | Rio Piedras  | Puerto Rico |
| Meharry | Nashville | Tennessee |
| Howard University | Washington | D. C. |

## Slide 26

| Community Networks to Reduce Cancer Disparities |  |  |
| --- | --- | --- |
| Institution | City  | State |
| Arizona Cancer Center | Tucson | Arizona |
| University of Alabama | Birmingham | Alabama |
| Hawaii Canter Center | Honolulu | Hawaii |
| University of Maryland | Baltimore | Maryland |
| Morehouse School of Medicine | Atlanta | Georgia |

## HOW DO WE ?

- MAXIMIZE OUR RESOURCES
- INTEGRATE OUR RESOURCES
- DEVELOP CRITICAL MASS
- PREVENT CARRY-OVER ISSUES

## First Year Observations

- These programs are cooperative agreements:
- 	that there is a role for CMBB staff in the conduct of these grants; in truth these are partnerships between

## THREE-WAY PARTNERSHIP

- MSI

- NCI

- CC

**THREE-WAY** **PARTNERSHIP**

## First Year Observations

- These programs are about building and sustaining excellence:
- 	other than long-term support for cancer research infrastructure )e.g., clinical accrual cores, tissue cores), we do not sustain any other activity
- 	every pilot/program should meet the highest standards of merit

## Indicators of Excellence

- Number of Abstracts
- Number of Presentations
- Number of Publications

- Number of Pilots to Full Projects
- Number of Grants Submitted
- Number of Grants Awarded

## VITAL ISSUE

- Scientific Mentoring
**Cancer center co-leaders initially should play a prominent role in ensuring the quality of a project and providing the kind of mentoring to the MSI co-leader that will enhance an independent career**
**MSI co-leader should initially play a more prominent role in ensuring the quality, sensitivity and effectiveness of projects/programs dedicated to minority education, outreach , and accrual to clinical trials**

## RECOMMENDATIONS

- Every project/program receive a full review by the committee in the cancer center that reviews the distribution of Cancer Center Development Funds
- Every partnership set a high-priority on working toward the goal where every Co-PI becomes a PI on a NIH-funded research grant

## RECOMMENDATIONS

- PSC reports be prepared with reasonable detail, identifying weaknesses and recommending ways to correct them and that all openly share their reports
- Every PSC meeting address the specific commitments of the MSIs to the partnership

## RECOMMENDATIONS

- Before the PSC meeting that the Co-PIs, CMBB staff person and chair of the PSC determine the most critical elements of an effective agenda and ensure that information is to be evaluated is distributed before the meeting.  This agenda should include responding to the last PSC meeting
- Every partnership initiate the development and begin implementing a training program that will eventually be submitted to the NIH as a T32, R25T/E, and/or K12 grant application

## WHAT FORM will the MI/CCP Program Take on in the FUTURE?

## Slide 37

## MODIFICATIONS

- Five Year Strategic Plan
- Monitoring and Recommending MI/CCP R01 Grants for Pay by Exception
- MI/CCP RFAs
- MI/CCP Non-Competing Guidelines