# Presentation: 484382

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

##  BD Biosciences 

##  BD Biosciences 

**HIV/AIDS**

- _Uses_
- 	HIV infection classification
- 	AIDS definition
- 	Prognosis
- 	Treatment (Decision-making)
- 	Monitoring
- 	Design clinical trials
- _Misuses_
- 	Biological variability
- 	Methodologic variability
- 	Interpretation of normal reference values, (lower range thresholds)

##  BD Biosciences 

- The group of individuals from whom the data to calculate the reference in terval was obtained.

- Reference Range:
- The entire data set of values obtained from the reference population from whom the reference interval is calculated.

- Reference Interval:
- The range of values statistically derived from data obtained from a reference population.  The interval represents the limits of normal or 95% of that population.  Reference intervals are also known as normal ranges and are used by clinicians for purposes of comparison to determine if a test result is abnormal.

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

## Slide 10

## Slide 11

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

** ****BD Biosciences**** **

##  BD Biosciences 

## BD Biosciences 

_**DEVELOPING COUNTRIES WHERE**_
_**BECTON DICKINSON HAS EXPERIENCE**_

**THAILAND**
**BRAZIL**
**SENEGAL**
**INDIA**

**BD Biosciences**** **

## Thailand

**HIV / AIDS NATIONAL PROGRAMS**

## Thailand

## Brazil

**HIV / AIDS NATIONAL PROGRAMS**

## BD Latin America – BD Biosciences Seeding the Field for Future Growth

**BD L****atin America – BD Biosciences**** *****Seeding the Field for Future Growth***

- Prevention

- Care &
- Treatment

- Social &
- Economical
- Impacts

-  Educational Approach to reduce AIDS incidence
-  Free Diagnosis and Monitoring Tests
-  72  centers for TCD4+/CD8+ tests
-  200.000 FACSCount tests per year - US$ 4,5MM in sales
-  Free  distribution of anti - retroviral drugs ( covering 424  sites)
-  Reduction of 50% of aids death and occurrences of opportunistic infections
-  Notable improvement in the quality of life of people with HIV infection
-  Financial Savings in treatments  - US$ 422MM over the last 3 years
-  Brazilian program is being fully supported by United Nations

## BD L

**Sponsoring**

**Supporting**

**Selling**

**Learning**

- •

- Annual CD4 network labs meetings

- •

- Educational Speeches

- •

- Brazilian Study to establish

- normal

- TCD4

- +

- /CD8

- +

- populational patterns

- •

- BD equipments and tests

- supporting

-  Govt’

- efforts as to

- clearly knows who is winning, the

- virus or the immune system, balancing

- drugs offering

- •

- Follow the expansion of the Brazilian

- program within the region, leveraging

- from a strong partnership with MOH

**BD L**

**BD L**

**atin America**

**atin America**

**–**

**–**

**BD**

**BD**

**Biosciences**

**Biosciences**

***Seeding the Field for Future Growth***

***Seeding the Field for Future Growth***

## FACSCalibur

**Versatility by Design**

**FACSCalibur**

## FACSCalibur Versatility

- FACSCalibur can be configured to each laboratory’s requirements, with the assurance that other options can be easily added as needs change:
- 3 or 4 color fluorescence (MultiTEST, TriTEST)
- Sorting
- Automated sample loading from tubes or plates
- Networking and LIS connectivity

## FACSCalibur Versatility

- Features
- Automated benchtop flow Cytometer
- Modular design
- Dual lasers optimized for 4 color analysis
- Single-platform absolute counting with TruCOUNT
- Optimized system with software, reagents, hardware & support

- Benefits
- Walkaway automation enhances productivity
- Flexible and upgradeable
- Minimal compensation and maximum flexibility in fluorochrome selection
- Decreased inter-laboratory variability in results
- Works with MultiSET System
- MultiSET software
- MultiTEST & TriTEST reagents (3 & 4 color)
- Multi-Check Controls

## FACSCount

**Simplicity and reliability**

## FACSCount Simplicity

- Features
- Easy-to-use
- Reliable
- Complete, stand-alone benchtop platform
- Consistent, accurate counts on samples with low CD4 values
- Automated QC, error conditions detected & flagged
- Absolute enumeration of CD4, CD8 and CD3 cells

- Benefits
- Minimal operator training
- Low maintenance costs
- No special hook-up or computers required
- Facilitates effective management of HIV therapy
- Confidence in results
- Comprehensive test menu

##  BD Biosciences 

**HIV / AIDS IN DEVELOPING COUNTRIES**
**Becton Dickinson Biosciences Technology Resources:**

##  BD Biosciences 

**HIV / AIDS IN DEVELOPING COUNTRIES**
**Becton Dickinson Biosciences Technology Resources:**