# Presentation: 493316

## Slide 1

## Fighting Cancer: From Prevention to Treatment

**In 2003, the National Cancer Institute (NCI) announced a **
** ****Challenge Goal:**
***TO ELIMINATE THE SUFFERING AND DEATH DUE TO CANCER BY 2015.***
**Key to this effort are strong programs in basic, translational, and clinical research to facilitate:**
**	****—****	****Basic discovery and new **
**	****	****	****	****technologies**
**	****—****	****Prevention and prediction **
**	****	****	****	****of disease onset**
**	****—****	****Early detection**
**	****—****	****Development and **
**	****	****	****	****use of treatments **

## Re-engineering the NCI Intramural Research Program:A Partnership Between CCR Staff, NCI Leadership 

**Accelerate Development and Use of New Technologies**
**Enhance Translational Research**
**Increase Partnerships With Industry**
**Restructure Review and Reward Process To Include  “Team Science” Activities**
**Improve Training**
**Interdisciplinary**
**Clinical**
**Biotechnology**

***Re-engineering the NCI Intramural Research Program:******A Partnership Between CCR Staff, NCI Leadership ***
***and the BSC***

## The Center for Cancer Research:The Big Picture

- Basic Research

- Clinical Research

**Advanced**
**Technology**

**Molecular**
**Oncology**

**Clinical**
**Infrastructure**

- Translational
-    Research

- HIV/AIDS Research

**Training**

## Areas of Emphasis in the Re-engineered CCR

**Areas of Emphasis in the Re-engineered CCR**

**Advanced Biomedical**
**Technologies**

**CCR**
**Clinical**
**Program**

**Molecular Targets & Molecular Oncology**

**Genetics & Genomics**

**Imaging & Biomarkers**

**Integrated**
**Systems**
**Biology**

**Immunology,**
**Immunotherapy & **
**Immunoprophylaxis**

** ****HIV/AIDS**

**Intramural/Extramural**

## Strategies and Structure for Programmatic Integration

**Centers for Excellence**
- Immunology
- Advanced Biomedical Technology
- Molecular Oncology
- Molecular Epidemiology

***Strategies and Structure for Programmatic Integration***

**Faculties and Working Groups**
- Disease
- Discipline
- Approach

**Cross-cutting Programs**
- HPV Vaccines
- Kidney Cancer
- Molecular Imaging
- Molecular Therapeutics Program

**Training**
- Tenure-track
- Postdoctoral
- Minority
- Interdisciplinary

**Basic **
**Science**

**Translation**

**Clinical **

**Technology**
**Development**

##  Four Centers of Excellence Serve as Focal Points for Bench to Bedside Translation

**	****These Centers of Excellence support the IRPs dedication to long-term, high-risk, innovative basic, clinical, and epidemiologic research.**
**	****Advanced Biomedical Technology**
**	****Molecular Epidemiology**
**	****Immunology**
**	****Molecular Oncology**

## Center of Excellence in Immunology

**Trans-disciplinary Membership in Immunology, Virology and Epidemiology**
**Integration of Basic and Clinical Goals**
**Approximately 250 Investigators From 20 Branches and Laboratories **
**Trans-NCI Membership**
**5 Members of NAS and IOM**
**History of Success in Training and Leadership**
**One Surgeon General, 2 Nobel Laureates, 7 Members Of NAS, 3 NIH Institute Directors, 1 NIH Deputy Director, 1 NIH Director**

## Center of Excellence in Immunology

***Center of Excellence in Immunology***

**Steering Committee**

**Scientific**
**Organizing**
**Committee**

**Meetings on**
**Immunology**
**and Cancer**

**Immunology**
**Faculty**

**Seminar **
**Series**

**Labs and**
**Branches**

**Vision and**
**Planning**

**Strategic Analysis of  Challenges. Leadership  and Future Vision**

**Training**

**Interaction within**
**NCI, NIH, Academics**

**Focus on**
**Specific**
**Cancers**

**Focus on Specific**
**Aspects of  Immunology **
**and Virology**

## Translational and Clinical Immunology in the CoE Immunology at the CCR

**Monoclonal Antibodies and Cytokines**
**Cell-based Therapies**
**Vaccines**
**Transplantation and Anti-Tumor Therapies**

## Slide 11

**Notes:**
And now to the best part of today’s meeting—a look at this remarkable new hospital.