# Presentation: 136992

## Atlanta
CTSA: Opportunities and Challenges

**Atlanta**
**CTSA: Opportunities and Challenges**

**ACTSI**

## Partnerships

**Partnerships**

**THE UNIVERSITY**
**OF GEORGIA**

## Goals

- Support cross-cutting scientific discovery, innovative initiatives, and their translation to humans through *novel and emerging technologies*.
- Establish a *culture of community engagement* and communication in clinical and translational research.
- Build upon, enhance, and expand successful *education programs, clinical research curricula, mentoring, training, and career development*.

## Interdisciplinary Programs & Strategic Themes 

## Programs

## Transformation

**Synergistic Partnerships**
- MSM: Community Engagement
- GA Tech: Nanotechnology and Biomedical Engineering
- CHOA: Pediatrics
- Yerkes National Primate Center
- UGA: Resource for Integrated Glycotechnology and Resource for Biomedical Glycomics
- Kaiser Permanente of Georgia
- CDC: Predictive Health Doctoral Training Program
- Georgia Research Alliance and Georgia Biomedical Partnership

## Pediatric Clinical Interaction Sites

## Atlanta CTSI Pilot & Collaborative Translational & Clinical Studies (“PiCo-TraCS”)

*Thorny-devil lizard, Great Victoria Desert, Australia*

## Seven $30,000 one-year awards funded:
“Airway adipokines and the alveolar macrophage,” Fernando Holguin, MD (Emory Pulmonary, Critical Care)
“Early intervention following severe trauma,” Debra Houry, MD (Emory, Emergency Medicine)
“Essential tremor disease mechanisms,” Claudia Testa, MD (Emory, Neurology) 
“Association of variants in SLC308A8 and TCF7L2 genes with insulin secretion in overweight/obese African Americans,” Yuan-Xiang Meng, MD/PhD/MSCR (MSM, Medicine)	
“Community associated MRSA in children: surveillance and treatment outcomes in the ambulatory setting,” Lilly Cheng Immergluck, MD (MSM, Pediatrics)
“Left ventricular hypertrophy and heart failure in obese African Americans: developing predictive adipokine biomarkers,” Aurelian Bidulescu, MD/PhD/MPH (MSM, Community Health and Preventive Medicine)
“Vitamin D Metabolite Loss into Urine Limits Optimization 
of Vitamin D Status during Vitamin D Supplementation, 
Cinnamon Bradley, MD (MSM, Medicine)

- “Airway adipokines and the alveolar macrophage,” Fernando Holguin, MD (Emory Pulmonary, Critical Care)
- “Early intervention following severe trauma,” Debra Houry, MD (Emory, Emergency Medicine)
- “Essential tremor disease mechanisms,” Claudia Testa, MD (Emory, Neurology)
- “Association of variants in SLC308A8 and TCF7L2 genes with insulin secretion in overweight/obese African Americans,” Yuan-Xiang Meng, MD/PhD/MSCR (MSM, Medicine)
- “Community associated MRSA in children: surveillance and treatment outcomes in the ambulatory setting,” Lilly Cheng Immergluck, MD (MSM, Pediatrics)
- “Left ventricular hypertrophy and heart failure in obese African Americans: developing predictive adipokine biomarkers,” Aurelian Bidulescu, MD/PhD/MPH (MSM, Community Health and Preventive Medicine)
- “Vitamin D Metabolite Loss into Urine Limits Optimization
- of Vitamin D Status during Vitamin D Supplementation,
- Cinnamon Bradley, MD (MSM, Medicine)

## ACTSI Translational Technology Programs

**focus areas aligned with strategic themes**

- Translational Technology Pipeline
- Proof Of Principle Technology Fund

## ACTSI Biomedical Informatics Program

- Health Disparities & Community Engagement

**Focus Areas**

**Infrastructure **

** ****Researcher**

- PORTAL

## ACTSI Research Ethics Consultation Service

- John Banja, PhD*Roberta Berry, JD, PhD**
- Martha Elks, MD, PhD***
- Karama Neal, PhD, MA (Bioeth.)*
- Rebecca Pentz, PhD*
- Karen Trotochaud, MN, MA (Bioeth.)*
- * Emory University  **Georgia Tech  ***Morehouse School of Medicine

## Education Programs

- A new dual degree program is now available to combine MD or Ph.D. training in the sciences with a M.S. degree in Clinical Research.
- Expanded Interdisciplinary Curriculum
- NIH Clinical Center

## Challenges

- Funding for Education Program especially KL Program
- Maintenance of Clinical Interaction Network: Pediatrics
- Community Engagement
- Time

## VA-Research Ctr

***VA-Research Ctr***

***CRCA/MSCR/K30/K12***

***Yerkes Primate***
***Research Ctr.***

***CDC***

***Emory University***
***Hospital***

***Crawford Long***
***Hospital***

***GCRC***

***Wesley Woods***