BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 134960

## Global Optimization: Visualizing Heuristic Strategies

- Rob Dimeo
- IDL/DAVE Lunchtime Seminar
- December 14, 2004

## Conventional Optimization Algorithms

-    one that requires only function evaluations...
-    or one that requires function evaluations and 	derivatives

- For functions that have multiple minima these algorithms can get caught in one of the local minima

## Heuristic Global Optimization Algorithms

- Many algorithms borrow from a natural paradigm
- Simulated Annealing
- Genetic Algorithm
- Particle Swarm Optimization
- Ant Colony Optimization

- Some are artificial constructs or ad-hoc
- Stochastic tree optimization
- Stochastic downhill simplex

- A common problem with global optimization algorithms:
- _Exploration vs. exploitation_

## The Simple Genetic Algorithm

- Based on Darwinian survival-of-the-fittest
- Search space encoded as chromosomes made of bits
- Solutions are *bred* using rules for reproduction, crossover, and mutation
- Population of solutions *evolve* for some number of generations (undergoing reproduction, crossover, and mutation) and the *best fit* solution is determined in the last generation
- Example: Solution of the 1-d Ising model

- Creation of initial population

- Fitness (function) evaluation

- Termination criteria met?

- Selection

- Crossover

- Mutation

- Determination of new population

- no

- yes

- Done

## Stochastic Downhill Simplex

- Standard downhill simplex (reflections, expansions, and contractions) augmented with a random restart
- At conclusion of a series of downhill simplex moves, the simplex is “exploded” and another series of downhill simplex moves proceeds
- Example: function minimization

## Stochastic Tree Search

- One point in search space defines a _node_
- From starting node branches are constructed to two new nodes
- Function (2) evaluated and stored at each new node
- Thickness of branch is related to the measure of probability for taking that branch in subsequent iterations

- Start at the original node
- Create branches to 2 new nodes
- Evaluate the function at each new node (save the minimum).  Assign branch probabilities based on function evaluation
- In the next iteration begin at the original node
- Choose branch based on branch probability until you reach a terminal node
- At the terminal node create 2 new nodes
- Repeat until some depth has been reached
- Enhancement: Specify a branch decay that reduces the probability based on the number of times that node has been visited

- Example: Function minimization
# Presentation: 915563

## Comparison of fits to obs of fnl and prynew

- 10 May – 19 May 2006
- Suru Saha, EMC

## RE-CAP

**26 April – 9 May 2006**
**BAD :**
**Antarctic Radiosonde stations show large temperature bias and rms errors at 850 hPa, as compared to the ops**

## Slide 3

## Slide 4

## NEW PLOTS after corrections 

**to TG3 and Terrain**
**10 May – 19 May 2006**
**GOOD : **
**Antarctic Radiosonde stations show similar temperature bias and rms errors at 850 hPa, as compared to ops**

## Slide 6

## Slide 7

## Pry1– run of pry taking out change to near surface long wave

- Results indicate slightly warmer surface and near-surface temperatures over Antarctic with old long wave, slightly reducing differences with operational

***1 degree files***

## Slide 9

## 90-60S

## Slide 11

## May 3-11, 2005

- Glenn.White@noaa.gov

***May 3-11, 2005***
***Pry.new covers May 9-15***

- Differences in 5 day forecasts between pry and operational and between pry.new (corrected orography in Antarctica and pry
- Much of the large differences between pry and operational over Antarctica appear to be due to erroneous orography

## Slide 13

## Mountains over Antarctica in pry.new are much closer to operational; so are surface temperatures over Antarctica

- 90S-90N

- 90S-90N

- 90S-90N

- 90-60S

## 2.5 degree files

## Slide 16

## Slide 17
# Presentation: 489662

## Pharmacy Care Alliance

**Medicare Approved Drug Discount Card**
**Special Endorsement for **
**American Indians/Alaskan Natives**

**September 30, 2004**

## Partnership.....

- Express Scripts, Inc.
- National Association of Chain Drug Stores (NACDS)

**2**

## Pharmacy Network
Over 200 AI/AN pharmacies (contracting)
Over 43,000 retail pharmacies nationwide
Mail Order pharmacies
Mashantucket Pequot Tribal Nation
Express Scripts

- Over 200 AI/AN pharmacies (contracting)
- Over 43,000 retail pharmacies nationwide
- Mail Order pharmacies
- Mashantucket Pequot Tribal Nation
- Express Scripts

- Open Formulary
- All drugs are covered except those not allowed by CMS

**Aspects of the Program**

**3**

## “Wrap-around products”
Deep discounts from certain pharmaceutical manufacturers are passed to beneficiaries once their $600 is used up at retails stores
Eil Lilly
Merck
Abbott
Novartis
Johnson and Johnson
AstraZeneca

- Deep discounts from certain pharmaceutical manufacturers are passed to beneficiaries once their $600 is used up at retails stores
- Eil Lilly
- Merck
- Abbott
- Novartis
- Johnson and Johnson
- AstraZeneca

**Wrap Around Programs**

**4**

## Easy to Enroll

- Mail
- Phone
- Fax
- Internet – www.PCAcard.com

**5**

## PCA receives application and checks for errors
If found, beneficiary is contacted
Submit to CMS within 24 hours

CMS review
Approved
Denied
Pending

PCA informs beneficiary
Approved – PCA sends ID card and welcome packet
Denied – Mail denial letter
Pending – Mail letter and call beneficiary

**PCA receives application and checks for errors**
- If found, beneficiary is contacted
- Submit to CMS within 24 hours
**CMS review**
- Approved
- Denied
- Pending
**PCA informs beneficiary**
- Approved – PCA sends ID card and welcome packet
- Denied – Mail denial letter
- Pending – Mail letter and call beneficiary

**6**

## Application Process

**7**

## Beneficiary Customer Service
1-800-PCA-7015
Beneficiary Internet Site
www.PCAcard.com
Pharmacy Customer Service
1-866-533-8515

**Beneficiary Customer Service**
- 1-800-PCA-7015
**Beneficiary Internet Site**
- www.PCAcard.com
**Pharmacy Customer Service**
- 1-866-533-8515

**8**

## Network Pharmacy
Patient Care Coordinator
AI/AN Clinics
Pharmacy Care Alliance Customer Service
www.PCAcard.com

**Network Pharmacy**
**Patient Care Coordinator**
**AI/AN Clinics**
**Pharmacy Care Alliance Customer Service**
**www.PCAcard.com**

**9**

## Questions

**10**
# Presentation: 678950

## Wilfred E. Mazur
Polar Satellite Acquisition Manager
U.S. Department of Commerce - NOAA
Polar Max 2004 Review
October 19, 2004

**Wilfred E. Mazur**
- Polar Satellite Acquisition Manager
- U.S. Department of Commerce - NOAA
- Polar Max 2004 Review
- October 19, 2004

**CHANGES FOR NOAA-N**

## Topics

**Spacecraft Overview**
**Changes to the Spacecraft**
**User Impacts**

## NOAA-N/18

- _Planned Launch_
-     Feb. 12, 2005
-     2:22 AM PST

## Launch Vehicle

**Launch Vehicle**

- Boeing Space and Defense
- Delta 7320-10

## Sun Synchronous Orbit

**Sun Synchronous Orbit**

- ORBITAL CHARACTERISTICS
- Apogee......870 km (470 nmi)
- Perigee ......870 km (470 nmi)
- Minutes per orbit........102.14
- Degrees inclination......98.730

## Slide 6

## Spacecraft Overview

- Fourth generation in TIROS-N Series
- Payload:
- AVHRR/3          Advanced Very High Resolution Radiometer
- HIRS/4               High Resolution Infra-red Sounder
- AMSU-A1,2      Advanced Microwave Sounding Unit
- MHS                  Microwave Humidity Sounder
- SBUV/2             Solar Backscatter Ultra-violent Radiometer
- SEM-2               Space Environment Monitor
- DCS-2               Argos Data Collection System
- SARR                Search and Rescue Repeater
- SARP                Search and Rescue Processor
- First IJPS satellite to be launched

## Changes to the Spacecraft

- AMSU-B is replaced by the MHS
- 5 channel Microwave radiometer
- 5 year design life
- Sophisticated data system allowing re-programmability

## Changes to the Spacecraft (Cont.)

- HIRS/3 replaced by HIRS/4
- IGFOV changed from 20Km to 10Km
- Improves quality of sounding by reducing  probability of cloud contaminated views
- AVHRR/3 upgraded with high torque scan motor
- Should significantly improve the reliability and life-time of this primary instrument

## Changes to the Spacecraft (Cont.)

- Automatic Picture Transmission (APT) frequencies changed
- 137.5   MHz ---> 137.1 MHz
- 137.62 MHz ---> 137.9125 MHz
- New frequencies have Primary use allocation
- Solid-State Digital Recorders replace Tape Recorders
- Provides 80% greater storage

## Changes to the Spacecraft (Cont.)

- Ring-laser Gyros replace mechanical gyroscopes
- Primary down-link transmitters (S-band) upgraded with reliability improvements
- Improvements to Flight computers:
- PROM-based copy of Flight software
- Rad-hard memory (fewer SEUs)

## Changes to the Spacecraft (Cont.)

- Other changes to the bus:
- MHS associated:
- MHS Interface Unit;
- Data system, command system, panel rearrangement, flight software
- Launch vehicle associated:
- New propulsion system
- Deleted AKM, hydrazine system
- Booster adapter and deployment systems
- New ascent/deployment flight software
- Ring-laser Gyro Associated:
- Flight software changes

## User Impacts

- MHS Data formatting and minor science algorithm changes from AMSU-B;
- APT Users must ensure their systems can operate with the new frequencies;
- HIRS/4 sounding algorithms must be adjusted for smaller field of view--gaps will exist between pixels.
# Presentation: 667537

## Poster Title 66 pt

- 2005, Michigan Technological University

**Poster Title 66 pt**

**Section Titles in 66 pt Bold Arial**

- Straight Text that is meant to be read from across the Booth should be in 44 pt

- Other stuff that people would read while standing right next to the poster could be smaller. This should only be for details or footnotes. This is 18 pt.

- This layout has the Institutional Logos along the bottom of the poster.   This way there will be lots of room in the case of joint posters and url’s and such.

- If we go with this banner on the poster than everyone will replace the language logo with the appropriate choice.  The PGAS logo will replace the text above.  This means that there will only be three different banners on the posters.

**White Arial Font Might be Quite Long**
# Presentation: 487890

## SSRL

- NSLS

- APS

- ALS

**Notes:**
Mission - to support basic research in the natural sciences leading to new energy technologies and to improved existing energy technologies.
Areas of research that underpin the mission include:
atomic , molecular, and chemical physics; catalysis; combustion dynamics; condensed matter physics; earth structure; fermentation microbiology; geochemistry; heavy element chemistry; materials physics; metallurgy; mineral reactions; organometallic chemistry; photochemistry; plant science; process engineering; robotics and control systems; rock deformation; separation science and analytical chemistry; solid dynamics; solid state chemistry; surface science; thermophysical properties.
Some dimensions of the program:
Over 2,000 research projects supported at DOE laboratories, universities and industries.
200 institutions supported
2,500 projects/proposals processed annually
1,300 projects/proposals externally peer reviewed
2,800 external peer reviewers
1 in 10 new proposals funded
Over 800 collaborations with industry
150 CRADAs
10 National User Facilities,4 microcharacterization centers  (12 cited on slide)
25 R&D 100 Awards since 1991
Numerous prizees and awards for PIs and students
1986 Nobel Prize in Chemistry -- Yuan T. Lee, University of California, Berkeley
1994 Nobel Prize in Physics -- Clifford G. Shull, MIT
1995 Nobel Prize in Chemistry -- F. Sherwood Rowland, University of California, Irvine
# Presentation: 660642

## Fuel Flammability Update

- International Aircraft Systems Fire Protection Working Group
- Phoenix, AZ
- March 26 - 27, 2003

- Steve Summer
- Project Engineer
- Federal Aviation Administration
- Fire Safety Branch, AAR-440

## LOC Testing – Work Update

- Compiled a more complete set of spark ignition data at sea level conditions at a range of THC concentrations and oxygen concentrations at and around 12%.
- Plotted results both as a function of altitude and as Fuel Concentration Vs. O2 Concentration at request of Boeing/Dr. Shepherd.
- Conducted a series of sea level hot surface ignition tests.
- Still no ignitions occurring below 12% O2.

## Facilities – Pressure Chamber

## Facilities – Pressure Chamber

- 353 ft3 pressure vessel
- Working pressure of 650 psi.
- Attached vacuum pump used to evacuate chamber to reduced pressures seen at altitude.
- Not capable of simulating temperatures seen at altitude.

## Facilities - LOC Test Article 

- 9 ft3 simulated fuel tank placed inside of vessel equipped with:
- Bottom surface heaters.
- 12 thermocouples.
- 2 piezoresistive pressure transducers mounted behind sintered porous metal discs.
- Interchangeable pressure relief mechanism.
- 1⁄4-in. aluminum plate.
- Foil diaphragm.
- Ignition source.
- 2 tungsten electrodes powered by 10 kV transformer operating at ~20 mA, providing 200 J/s

## Apparatus – LOC Testing

## Apparatus – LOC Testing

## Ullage Vapor Sampling

## Test Program

- JP-8 LOC Tests
- Mass Loading ~ 4.5 kg/m3
- Ambient pressure corresponding to altitudes of 0, 10, 20, 30 and 38 kft
- Ullage oxygen concentrations ranging from 21% to below the determined LOC
- Tests conducted with two different pressure relief mechanisms
- 1⁄4-in. aluminum plate
-  Ignition = movement of plate
- Foil diaphragm
- Ignition = rupture of foil

## Slide 10

## Slide 11

## Slide 12

## Slide 13

## Slide 14

## Slide 15

## Slide 16

## Slide 17

## Hot Surface Ignition (HSI) Testing

- Purpose
- To determine if the LOC determined by spark ignition testing (12% O2) was also sufficient to protect against ignition from some hot surface existing within the tank.
- Test Setup
- Setup was identical to the spark ignition testing.
- In place of spark, a 3" x 6" x 1" metal block was heated by two cartridge heaters for use as the ignition source.
- Conducted only at sea level conditions.

## HSI Testing - Results

- At 21% O2, ignition was achieved at a hot surface temperature (HST) of approximately 1350oF.
- A half-dozen other tests were conducted at O2 concentrations ranging from ~11.5 – 14%.
- Though some “puffs” of smoke could be seen as the HST approached ~1200o F, no ignitions occurred.
- Therefore, HSI within the fuel tank provides no more of a threat than spark ignition.
# Presentation: 706362

## Teaching WorkshopBovine Spongiform Encephalopathy (BSE)

- Air-injection Stunning

## Air-injection Stunning Prohibited

- January 12, 2004
- FSIS published an interim final rule with request for comments.  (69 Fr 1885, January 12, 2004)
- Amends FSIS regulations to prohibit air-injection stunning of cattle.

## Air-injection Stunning

- “Captive bolt stunners that deliberately inject compressed air into the cranium at the end of the penetration cycle shall not be used to stun cattle.”  (313.15 (b) (2) (ii))

## Harvard Study

- Harvard Center for Risk Analysis conducted a  risk assessment for BSE:
- FSIS commissioned the study and released the results on November 30, 2001.
- Among other things, the risk assessment compared standard captive bolt stunning and captive bolt stunning with air-injection.
- Found that air-injection stunners can fail on occasion and result in an increase of CNS tissue disseminated into the circulatory system of cattle, thereby increasing the probability of BSE agent transfer.

## Air-injection Stunning and BSE

- Other studies have shown that:
- Air-injection stunning can force visible pieces of brain and other Central Nervous System (CNS) tissue—known as macro-emboli—into the circulatory system and organs of stunned cattle.
- Most of the infectivity in cattle that have BSE is found in the CNS tissue (brain and spinal cord).

## European Commission Opinion

- In early 2002, the European Commission’s Scientific Steering Committee concluded that air-injection stunning was the method which had the highest risk of disseminating CNS tissues to other tissues and organs.

## Air-Injection Stunning

- Changes in regulations:
- Previous regulation 9 CFR 310.13 specifically listed air-injection captive bolt stunning as an approved method.
- Amended to prohibit its use in cattle.
- Regulation 313.15 (b) (2) (ii)
- New paragraph added to prohibit air-injection stunners.

## Stunning Devices Used in the U.S.

- Two types of captive bolt stunners:
- Penetrative
- Non-penetrative
- Most cattle slaughter plants in U.S. use penetrative captive bolt stun guns (without air-injection).
- FSIS does know that very few, if any, plants in the U.S. use air-injection stunning.

## Stunning Methods

- FSIS inspection personnel verify that slaughter plants are using approved stunning devices.

## Imported Beef

- Imported products must meet all safety standards for products produced in the U.S.
- Therefore, foreign establishments that use air-injection stunning for cattle are prohibited from importing beef products into the U.S.

## The Future

- There are relatively few studies on stunning techniques and CNS tissue.
- If further studies indicate that other stunning techniques introduce CNS tissues into the circulatory system of cattle, FSIS will consider prohibiting their use as well.
# Presentation: 348747

## Poor Research Designs in Policy Impact Studies: “Lies, Damn Lies, and Statistics”

**AHRQ 2007 Annual Conference: **
**Improving Healthcare, Improving Lives**
**September 26, 2007**
**Stephen Soumerai, ScD**
**Department of Ambulatory Care and Prevention**
**    ****Harvard Medical School and Harvard Pilgrim Health Care**

## Weak Designs: No Causal InferenceWhat Threats to Validity?

- Treatment Group

**Weak Designs: No Causal Inference****What Threats to Validity?**

**Posttest-Only Design with Nonequivalent                **
**Groups (cross-sectional)**

- Treatment Group
- Comparison Group

## Strong Quasi-Experimental Designs

**Strong Quasi-Experimental Designs**

## Reported Effectiveness of Printed Education Materials Alone in Well-Designed vs. Inadequately Controlled Studies

**Adequately Controlled Studies**

**Inadequately Controlled Studies**

- Soumerai et al, Milbank Q 1989; 67: 268-317

## Effect Attributed by MCOP

**Effect Attributed by MCOP**

**Example of an Inadequate Cross-sectional Design: Problems with Small Samples and Outliers**

## Post-only Evaluations of Several Drug Cost-Containment Policies on Medication Use and Health Outcomes 

**Conclusions:** Mixed effects on outcomes and costs
**Design:** Post-policy comparisons of several groups (e.g., with and without employer insurance)
- No data on baseline comparability
- Statistical adjustment for group differences
**Problems:**
- Study groups were already different with respect to SES and health status
- Instrumental variables, propensity scores, etc. can’t fully control for bias

## Use Longitudinal Models

- Increases statistical power in quasi-experimental studies
- Uses information  on trends
- Multiple pre- and post-measurements of outcomes
- Provide graphical evidence: 			visible versus statistical

## Figure 1: Reductions in benzodiazepine use after Triplicate Prescription Policy among patients living in neighborhoods with different racial compositions

**Triplicate Prescription Policy**

**Figure 1: Reductions in benzodiazepine use after Triplicate Prescription Policy among patients living in neighborhoods with different racial compositions**

- Pearson et al, Arch Intern Med 2006; 166:572-9

## Benzodiazepine Use and Incidence of Hip Fracture among Women in Medicaid Before and After NY Regulatory Surveillance

- Cumulative Incidence of Hip Fracture per 100000 Female Users before Policy

- Bz Use among Female Users before Policy,%

## Summary Points

- Longitudinal data allow for strong quasi-experimental designs
- Provide more valid results
- Visible effects almost always significant
- Creative use of comparison series
- Unexposed comparison population
- High risk subgroups
- Unintended outcomes
# Presentation: 193969

## “Experiences for Youth”

- 2006 New Haven Science Fair at the Yale University Commons with CRISPEY participants

**“****Experiences for Youth”**

- The CRISP "Experiences for Youth" (CRISPEY) Mentorship Program was established to provide enrichment and professional guidance to K-12 students participating in the New Haven Science Fair.  The science fair plays a central role in the curriculum for New Haven public schools which includes an 89% enrollment of under-represented minorities.  Around 8,000 students participate in the fair each year.  This mentorship program promotes interest in the field of materials science through the thrill of scientific discovery. This year CRISPEY sent five projects to the New Haven Science Fair with three students being honored with 1st place awards in their respective categories.
# Presentation: 924390

## Sportfishing 

- Sportfishing
- in America - 2015

## Fishery Conservation and Management Act of 1976 

**	**PURPOSES:
- 	To Control The Level Of Foreign Fishing in the U.S. EEZ
- 	To Encourage the Use of Under-Utilized Stocks
- 	To Conserve and manage the Fish Found in the U.S. EEZ
**	**
**	**

## THE SUSTAINABLE FISHERIES ACT of 1996

- NEW PROVISIONS
- Stop Overfishing
- Minimize Bycatch
- Protect and Restore Habitat

## RESULTS OF THE SUSTAINABLE FISHERIES ACT

**	****	**
**RESULTS **
***Since 2000:***
- 17 Major Stocks rebuilt or removed from overfished stocks list
- 93% of remaining overfished stocks have rebuilding plans
- Overfished species decreased by 37 (48%)
- Unknown status stocks decreased by 48 (25%)
***In 2003 alone:***
- Overfished Stocks --     Down by 10
- Overfishing	         --     Down by 6 Stocks
- Fully Rebuilt           --     4  Stocks

## Saltwater Recreational Fishing 2015 Predictions

- Improved recreational data
- Evolution of recreational management
- Increased scrutiny of recreational fishing
- Increased advocacy by the recreational community
- Increased participation by recreational anglers
- Restoration of most overfished stocks

## Saltwater Fishing2015 Challenges

- Fishery allocations
- Habitat and water quality
# Presentation: 267465

## http://www.cfconventions.org

**CF Conventions Support at PCMDI**

**Kyle Halliday, Dean Williams, Karl Taylor****June 11-13, 2007****UCRL-PRES-231560**

- _[http://www.cfconventions.org](http://www.cfconventions.org/)_

## Overview

**CF Website Transition Summary**
**Discussion Forums (beta testing)**
**Outstanding Issues + Future Work**
**Discussion**

## New website at PCMDI is “Live”

**Server Setup**
**Collaborative Website (Plone)**
**Discussion Forums (Trac)**
**Document Version Control (Subversion)**
**cfconventions.org**
**Content Transition**
**CF Conventions document fully ported to new website (DocBook XML)**
**Scripts for automatic generation of HTML, PDF documents**
**Discussion Transition (beta testing)**
**Standard mailing list, archives continue to be hosted at NCAR**
**Trac set up with mailing lists, “components” for working groups**

## Discussion Forums (Trac)

**View Tickets – shows “Open” tickets by default**

## Ticket Detail

**Ticket Metadata**

**Reply Buttons**

## New Ticket

**CF Template Button: **
**Insert text for **
**structured proposal**

## Outstanding Issues + Future Work

**Trac “blank screen” problem**
**Due to server software conflicts**
**New server ordered – dedicated to hosting collaborative webapps - is in the mail**
**Continued development of Trac Templates**
**Discussion templates for better standardization of discussion process**

## Discussion
# Presentation: 047905

## NHLBI Review of Clinical Trials 

- Valerie Prenger, PhD, MHS
- Chief, Review Branch
- National Heart, Lung, and Blood Institute

## Where are the trials reviewed?

- Single Site Clinical Trials (R01)
- Most are reviewed by Center for Scientific Review (CSR)
- Reviewed in appropriate study section according to standard referral guidelines
- Multi-site Clinical Trials (R01)
- Require a staff visit with NHLBI staff
- Program Division representative (DHVD, DLD, DBDR, DECA)
- Review representative
- Reviewed by NHLBI’s Clinical Trials Review Committee (CLTR)

## Grant review by CLTR

- Standing Committee made up of experts in clinical trials of Heart, Lung, and Blood diseases (i.e., clinicians, biostatisticians)
- 1-2 Ad-hoc reviewers brought in for each clinical trial reviewed
- Standing members of CLTR read all applications
- Standard review criteria and scoring system used
- Human Subjects issues scrutinized carefully
- Applications are percentiled against other R01s received for that round (i.e., no set aside money)

## Standing membership of CLTR

- 16 members total
- 1 chair (currently a pulmonologist)
- 6 cardiovascular clinicians
- 2 pulmonary clinicians
- 2 hematologists
- 4 biostatisticians
- 1 behavioral medicine/epidemiologist

## Types of studies reviewed by CLTR

- multi-site clinical trials
- ancillary studies to previously funded multi-site trials
- supplements to previously funded multi-site trials
- multi-site cohort studies requiring extraordinary coordination (across sites) of a clinical endpoint

## Characteristics of CLTR review

- workload – approximately 12 studies per round
- multiple applications per study
- 2 day in-person meeting
- multidisciplinary review
- each study receives 1 score
- if multiple applications were submitted, the whole group of applications sinks or swims together – with the same score
- 1 integrated summary statement per study – budget comments are organized by application at the end of the summary statement

## Typical study reviewed by CLTR

- enrollment of 2,000 patients
- 6-9 sites (have had as many as 150 sites)
- separate Data Coordinating Center application
- reviewed together with Clinical Center(s)
- “routine” conflicts of members handled using standard NIH policy

## Review of applications by standing members

- reviewed by a SEP in NHLBI
- organized and conducted by different SRA
- current CLTR members are not allowed to participate in SEP
- attempt made to recruit past CLTR members that did not serve with member being reviewed
- telephone review
- percentiled against all R01s received in that round
- anecdotally, no advantage or disadvantage to being reviewed in a SEP when compared to CLTR review
# Presentation: 085839

## SEB Innovations

*Debra Johnson**Director**Office of Procurement / JSC*

## Agenda

- New Space Exploration Vision
- JSC Core Competencies – Human Exploration
- Improvements in the JSC Procurement Process
- Open Communications Leads To:

## New Space Exploration Vision

-     “This cause of exploration and discovery is not an option we choose; it is a desire written in the human heart”.
-                                      President George W. Bush

## JSC Core Competencies – Human Exploration

**Synergy for Success**

**Flight Crew**

**Operations**

**Engineering**

**Space and Life Sciences**

**Program Management**

**EVA**

## Improvements in the JSC Procurement Process

- Specific website established for each significant competitive procurement which will include:
- Request for input regarding strategy
- Schedule
- Link to technical library
- Post rules for Communications with Industry

## Improvements in the JSC Procurement Process (cont’d)

- Limit proposal data to what is necessary for selection.
- Technical organizations and source evaluation boards have been requested to limit proposal data to only what is needed during the competitive process
- This is particularly relevant to the data requirements documents (DRDs)
- During the review/approval process RFPs are closely scrutinized regarding the necessity of each DRD and other procurement data
- Anything not needed for selection will be required after contract award

## Improvements in the JSC Procurement Process (cont’d)

- Improve Schedule accountability
- JSC will publish a schedule template on the website for each procurement
- Schedule changes will be communicated, with rationale, to potential offerors via the website
- JSC will consider impacts of holidays when schedules are created or changed

## Improvements in the JSC Procurement Process (cont’d)

- Encourage greater early participation from interested parties
- JSC will ask for feedback regarding the procurement strategy
- JSC will include schedule milestones for incorporating of feedback received from Industry on the draft RFP
- JSC will assure that draft RFP transmittal letters clearly request feedback

## Improvements in the JSC Procurement Process (cont’d)

- Publish all Source Selection Statements
- Source Selection Statements will be available on a centralized website; (http://procurement.jsc.nasa.gov/procpub.htm)
- Anonymous questions/comments to draft RFPs can be submitted
- Address used to submit anonymous questions or comments is located on the procurement website
- Responses to anonymous questions or comments will be posted on the procurement website

## Improvements in the JSC Procurement Process (cont’d)

- Make debriefings more open
- JSC has been providing data to offerors beyond the requirements of recently published debriefing guide (PIC 04-11)
- Conduct survey after procurement to get feedback from offerors

## Open Communications Leads To:

- Improved proposals
- Improved contracts
- Mission success

## Constellation Program Overview
# Presentation: 867278

## Reconfigurable Environmentfor Analysis and Test ofSoftware Systems

- Sam Martin
- 304-333-2680
- smartin@prologic-inc.com

***REATSS***

## REATSS Overview

- Provides NASA IV&V an ability to perform cost effective dynamic analysis
- Enables detection of critical problem classes beyond static analysis
- System/algorithm stability and performance margin
- Race conditions, synchronization
- Interface discordance
- Complex hardware (sensor/effector) management and control
- Error/exception handling
- Control/branching logic including state transitions
- Operation and stability at input domain boundaries
- Incorporates net centric architecture and specialized development tools for rapid integration of test environment components

## REATSS Architecture

## Key Technologies Employed

- Eclipse RCP
- REATSS User Interface
- RTI’s Network Data Distribution Service (NDDS)
- REATSS Net-Centric Communications
- Reliable, Real-time Communications
- Pitch Technologies’ IEEE 1516 Portable Run-Time Infrastructure (pRTI 1516)
- IEEE 1516 High Level Architecture (HLA) compliant
- Prescribed Standard For Military Simulation Interoperability Within NATO
- Outlined in The Crew Exploration Vehicle (CEV) Simulations and Support Plan
- Subversion
- REATSS Repository Management

## Key Technologies Developed

- Generic Reconfigurable Interface for Messaging (GRIM)
- Supports Object Management Group (OMG) Data Distribution Service (DDS) v1.0
- Supports IEEE 1516 High Level Architecture (HLA)
- Runtime Configurable (XML) Publish/Subscribe Interface
- Simulation Executive (SimExec)
- Mode Control
- Health Monitoring
- Exception Handling
- REATSS Management and Control (Eclipse Based)
- Create Component Based Simulations
- Create and Debug Scripts
- Automatic Version Controlling
- Repository Management
- Real-time Monitoring, Graphing
- Fault Injection, Variable Overriding
- Breakpoints
- Script Execution
- Checkpoint Saving/Loading
- Script Engine
- Python Based
- Compatible with Python Interpreter
- Managers
- Automatically and Intelligently Distributes Simulation Components at Runtime

## Future Activities

- Development
- Processor Emulation
- Increase library of models
- Real-time Capabilities
- Executive Time Control
- Real-time Violation Detection
- Component Synchronization
- Planning
- Preparation for Pilot Program
- Establish cooperative component sharing relationships across NASA
- Identify REATSS use opportunities
# Presentation: 030698

## University of Chicago MRSEC 0213745 

**MRSEC’s Contemporary Leonardos**
**Sidney R. Nagel**

- A new temporary exhibit on Leonardo DaVinci at the Museum of Science and Industry in Chicago highlights his work and genius and features specially commissioned prototypes of his inventions.  Part of this exhibit describe the work of Modern-Day Leonardos—contemporary artists and scientists displaying unusual creativity in the spirit of DaVinci.
- Profiles of our current and former Directors, _Sidney_** **_Nagel_ and _Heinrich_** **_Jaeger_ were included in this special section.  A brief biography of each was on display, highlighting their areas of scientific interest, and representative samples of their research.  These included replicas of our MRSEC’s classical experiment on the fission of water droplets, and a movie illustrating the dynamics of granular phenomenon were included in this exhibit.

- Timed to coincide with the release of the blockbuster movie, The DaVinci Code, this exceptional exhibit drew over 199,000 visitors—many of them school groups from the Chicagoland area.

**Notes:**
Placard at left profiles Contemporary Leonardo, Heinrich Jaeger, former director of the University of Chicago MRSEC.

Picture at right show profile of Modern Day Leonardo, current MRSEC Director Sidney Nagel (foreground), with a portrait of the break-up of a high viscosity droplet (PRL, 83, 1147, (1999)) and movie of the behavior of granular materials in a Hele Shaw cell.
# Presentation: 189592

## OZARK AQUIFER FORUM

- Walt Aucott
- USGS, Lawrence, Kansas
- Ozark Aquifer Project Coordinator
- Director, Kansas Water Science Center
- _[waucott@usgs.gov](mailto:waucott@usgs.gov)_
- 785-832-3505

## Why are we here?

- Study plan and objectives
- Study status and progress
- Some basic ground water 		information

## Why is a ground water study needed?

- Ground water level declines and water quality problems indicate a water availability issue
- Some information available, but it is incomplete and needs regional perspective, especially due to interstate aspects

## Meeting Format

- Primer on ground water hydrology
- Jim Vandike –
- 		    Missouri Division Natural Resources
- Al Macfarlane -
- 		    Kansas Geological Survey
- Study overview
- Informal discussions
- Modeling presentation
# Presentation: 383281

## Run-5 Update

## Status: 5 weeks

- _Total from January 11 (_nbarn-1)
- Phenix:		9.16
- Star:		9.00
- Brahms:	3.86
- Phobos: 	3.36

## Luminosity / week

## Week 5 - Highlights

- Phobos A (Tuesday)
- Machine development (Thursday – 5 h):
- 	solve blue loss at gammat4
- 	chromaticity measurements
- 	deal with loss yellow at snapback (dynamic tuning + yellow Qh0.215)
- Phobos pressure rise onset (Thursday)
- Phobos B (Friday)
- Machine maintenance necessary (Friday – 2-3)
- 	orbit at IR6, store  (Vadim)  STAR background, TPC
- stochastic cooling development – BTF measurements (Mike Br+Bl)
- Stable running over weekend
- Beam Ex (Monday)-> decoupling on ramp yellow (Yun)
- 				         IR correction yellow (Fulvia, Vadim)

## Intensity/collisions – Week 5

**Phobos********PolA**

**Phobos********PolB**

**maintenance**

**development**

**Phobos PR**

## Store 6165   37x(4.8-5.0) – 96% 93%

- No lifetime problems – Phenix initial ~50K
- 12 minutes ev-lumi to collimation done

## Phobos PR and background

- Bunch intensity 37x 4.8-5.0 e9

- Bunch intensity 37x 4.6-4.7 e9

## Phobos operations – status

- 	OBSERVATIONS
- Onset with 6139 – total intensity at store 170+e9
- Almost all stores had it from 6139 (Thu eve) to 6165 (Sun eve)
- Takes 1-3 h to subside
- 34x34 did not make a difference
- Static pressure rise increase factor 2-3 prior to 6139
- Limiting intensity to **37x4.6 **helps (5 ramps)
- 	REMEDIES
- Sublimation (Vacuum group, maintenance)
**Limit** **total intensity** **37x4.6**     luminosity impact:
- 	4.54.8 at injection  4.54.2 at store    initial rates:48K42K
- 	Limit to 37x4.6 *till Phobos achieves goal*, then increase to **37X(4.8 -5)e9**
- 	test again 34x34 bunch pattern
**28x28 6e9**  re-develop ramp (instabilities, ramp transmission)
**	****	****	****   ****time**, impact on **reliability** (i.e. injectors)

## Machine development  week 6

- Change Star, Phenix, Phobos  magnet polarity
- 	(RHIC shifts back ON until job is done – estimate ~2 shifts)
- IR BPM offsetsorbit *(Todd, Vadim)*
- Auto-orbit correction
- Investigate loss at IP4 (real?)
- Commission 37x38 pattern for stochastic cooling *(Wolfram)*
**Orbit correction yellow** vertical at beta* stones (Vadim)
**Coupling correction** yellow beta* stones (Vadim, Yun, Fulvia)
- Vernier scans** **at 4 experiments *(Angelika)*

## 3-way polarity switch

- After ~2 shifts  2 stores overnight
- Transmission 93% 87% needs improvement (was 96% 92% before ‘swotch’)
- Plan ~4 hours development after store tomorrow to improve efficiency – then hopefully straight physics running
# Presentation: 108870

## An X-Y-Z magnet for polarized neutron reflectometryR. Goyette, H. Belch, K. Volin, S.G.E. te Velthuis, S. Srinath and G.P. Felcher Argonne National Laboratory, Argonne IL 60439 and M.N. Jirmanus, Janis Research Company, Wilmington, MA 01887

-  The polarized neutrons reflectometer POSY I at IPNS has been equipped with a magnet composed of 3 mutually perpendicular pairs of superconducting coils.
-  The pairs provide magnetic fields on the sample up to 8 and 20 kOe in the horizontal plane (which is also the scattering plane), and 8 kOe in the vertical direction. The coils are independently controlled.
-  The sample -with a maximum diameter of 2.5 cm-  is temperature controlled between 1.6 and 300 K.
-  Clear passages are provided for neutrons transmitted through the major axes of the two horizontal fields, with only 2mm Al on the neutron path.
-  An automated horizontal motion allows precise positioning of the magnet in the neutron beam, and a jack lifts the magnet out of the way when not needed.

-  The 20 kOe field, when applied perpendicularly to the surface, is larger than the shape anisotropy for most magnetic systems, and is sufficient to nullify the magnetic scattering.
-  The applied field can orient the polarization of the neutron beam in any direction. These features will greatly increase the usefulness of polarized neutron reflectometry in studying the magnetic phenomenology of thin films and multilayers.

-  The X -Y-Z magnet provides a new degree of flexibility in reflectivity experiments. The magnetic state of a sample is dependent on its history, and the combination of fields and temperatures control allows virtually all kind of magnetic and  cooling cycles.
# Presentation: 313558

## How to increase H-dispersion for BL 5.3.1

- Simulation overview
- Preliminary results of two experiments
- Summary and perspectives

- _L. Nadolski_, S. Lidia, C. Steier, D. Robin, and S. Zholents

## Effects of the shunts on the dynamics

| shunt | alpha | etax (m) | Eff. etax (m) |  
etax (m) | Dbetax (%) | Dbetay (%) |
| --- | --- | --- | --- | --- | --- | --- |
| %  |   | 5.3.1 | 5.3.1 | 6.0 | beta-beating | beta-beating   |
| 0 | 1.37E-03 | 7.10E-02 | 8.10E-02 | 6.10E-02 | 0 | 0 |
| 3 | 1.39E-03 | 8.70E-02 | 9.80E-02 | -5.00E-04 | 20 | 10 |
| 6 | 1.41E-03 | 1.03E-01 | 1.17E-01 | -7.00E-02 | 40 | 20 |
| 9 | 1.42E-03 | 1.18E-01 | 1.35E-01 | -1.34E-01 | 80 | 35 |

| nux | nuy | xix | xiy |
| --- | --- | --- | --- |
| before |  any | correction |   |
| 14.25 | 8.20 | 0.40 | 1.40 |
| 14.22 | 8.21 | 1.20 | 1.80 |
| 14.19 | 8.23 | 2.00 | 2.19 |
| 14.15 | 8.24 | 2.86 | 2.59 |

## Experiment @ 1.5 GeV (wiggler open)
More convenient, since no need to ramp (smat, rfscan)
Rfscan more dynamics
Momentum acceptance scales with energy  (DA as well)
Wiggler does not impact so much @ 1.9 GeV

Tune the lattice (not a trivial exp.)
Measure response matrix (beta-beating)
Momentum acceptance (lifetime)

Low injection efficiency with shunts on

- More convenient, since no need to ramp (smat, rfscan)
- Rfscan more dynamics
- Momentum acceptance scales with energy  (DA as well)
- Wiggler does not impact so much @ 1.9 GeV
- Tune the lattice (not a trivial exp.)
- Measure response matrix (beta-beating)
- Momentum acceptance (lifetime)
- Low injection efficiency with shunts on

- Preliminary studies – experimental conditions

## 
Elastic Scattering

Touschek  Effect

Quantum Lifetime

Inelastic Scattering

- Elastic Scattering
- Touschek  Effect
- Quantum Lifetime
- Inelastic Scattering

- (1)

- (2)

- (3)

- (4)

- Lifetime Limiting Processes

## Measure Touschek lifetime as a function of RF-voltage

Fit Measured Data with:
a constant correction for the bunch volume
a correction for the change of bunch length with rf
the momentum apertures in the arc and straight section

- Fit Measured Data with:
- a constant correction for the bunch volume
- a correction for the change of bunch length with rf
- the momentum apertures in the arc and straight section

- Measurements of Momentum Aperture

## Momentum acceptance measurement

## Summary and perspectives

| Shunt (%) |  εarc (%) | Tlife (%) |
| --- | --- | --- |
| 0 | 2.44 | 100 |
| 3 | 2.11 | 75 |
| 6 | 2.03 | 69 |
| 9 | 1.94 | 63 |

-  Check fitting routine for momentum acceptance
-  Redo experiment @ 1.9GeV
-  If almost viable, compensation of the beta-beating
-  Get new lattice to operation

- @ 1.9 GeV: εarc =2.6%
# Presentation: 763989

## ILWS Activities 

**in Slovakia**

- Karel Kudela
- IEP SAS
- Košice, Slovakia

**ILWS Steering Committee and Working Group Meeting Prague, June 10–12, 2008**

## ILWS science in Slovakia

**Institute of Experimental Physics, SAS, Košice **
**    ****(Department of Space Physics)**
- Energetic particles in space (solar, interplanetary, magnetospheric processes)
- Cosmic Rays (ground based observations) and space weather *http://neutronmonitor.ta3.sk*
- More at ***http://space.saske.sk***

*Based on individual activities of the Institutes of Slovak Academy of Sciences, and of the Universities*

## ILWS science in Slovakia

**Astronomical Institute of SAS, Tatranská Lomnica**
- solar outer atmosphere activity using combined space-born satellite instruments (SOHO: SUMER, CDS, EIT;TRACE, RHESSI, STEREO) and ground-based telescopes (DOT/LaPalma, SST/LaPalma,VTT/Tenerife)
- Ground based coronographic measurements
- More at  ***http://www.astro.sk/****** ***

## Geophysical Institute of SAS, Bratislava
	- Magnetospheric physics

Faculty of Mathematics, Physics and Informatics, Comenius University Bratislava
    - cosmogenic nuclides, links of cosmic rays to  environmental 	studies 

- 	- Magnetospheric physics
**Faculty of Mathematics, Physics and Informatics, Comenius University Bratislava**
**    **- cosmogenic nuclides, links of cosmic rays to  environmental 	studies

- ILWS science in Slovakia

***More at http://nccospar.saske.sk***

## Participation in space missions

**  ****Presently**** in orbit**** (in cooperation with other laboratories in abroad)****:**
- 	 -  Double Star (TC-2), energetic neutral atoms NUADU
-       **Rocket experiment** (HotPay2, recently, in Norway, energetic electrons)

**Data from past satellite experiments:**
- Interball-1, 2 and subsatellite – energetic ***e,p***  DOK exp, 1 s data (IEP SAS)
- CORONAS-F – SONG (gamma and neutrons) – plots at ***http://space.saske.sk/projects/songm/data.php?lang=1***

## Future missions

**Radioastron (SPEKTR-R):**** **
**	****  **-   MEP-2 energetic particles (IEP SAS)
**Resonance****:**
- DOK-R energetic particles (IEP SAS)
**Interhelios****:****  **** **
- Solar neutrons, gamma (IEP SAS?)
**BepiColombo****:**
- PICAM ion mass spectrometer (partial contr. IEP SAS ?)
**Solar Probe****:**** **
- Solar neutrons, gamma (IEP SAS??, expression of interest)
**Cosmic Vision 2015 – 2025 proposals:**
**	****Cross-Scale**** **
**	**** ****-    **Energetic particle detector (expression of interest, IEP SAS, jointly
- 		 with others?**)**

##      IHY related activities

**Participating institutions**
-     Astronomical Institute of SAS, Tatranská Lomnica Geophysical Institute of SAS, BratislavaInstitute of Experimental Physics, SAS Košice Slovak Astronomical Society
- 	Slovak Union of Astronomers Amateurs
**IHY Slovakia website**
-       http://ihy.saske.sk

## Future meeting related partially to ILWS

***21******st****** European Cosmic Ray Symposium in Košice, Slovakia***9. - 12. September 2008
- http://ecrs2008.saske.sk
# Presentation: 828611

## Low pass filter and HV – prototype

- capacitor 1210 (3.9nF)
- (2.5 x 3.2 x 1.27 mm)

- 15.5 mm

- spacer for wire bonding

- substrate under cables

- resistance 0603 (10k)
- (1.6 x 0.81 x 0.9 mm)

- Al foil to back plane (2mm width)

- +HV

- GND

- 12 mm

- 8 mm

- 3 mm

## Connection to the sensor

- 15.5 mm

- 3mm

- n+ (+HV)

- p+ (GND)

- 4 mm

## HV connection to the backplane

- sensor

- kapton insulator

- electrically non-conductive glue

- Al foil

- electrically conductive glue

- thermally conductive material  need choice

- side view

- bottom view

- 2 mm

- 16.5 mm

- 5 mm

-  3 mm

-   5 mm
# Presentation: 740538

## NAI Website: Member Usage 

- This portion of the presentation provided at the request of the NRC committee, to answer questions on use of the website by NAI members.

- Title of Presentation

## NAI Website: Member Usage

- The NAI Website serves two important constituencies: The Astrobiology Community and the science-interested public
- The potential size of these constituencies is very different, of order 108 public and 103 astrobiologists, so it is natural that we get more traffic from the public
- The first priority, as reflected in quantity of material and commitment of staff time, is to serve the astrobiology community

- Title of Presentation

## Number of Page views by 12 Lead Team Institutions (May 2007)

- Ames: 750
- GSFC: 547
- Berkeley: 209
- IPTAI: 171
- Penn State: 184
- Carnegie: 159

- UCLA: 143
- Hawaii: 123
- Colorado: 119
- Arizona: 118
- SETI: 72
- MBL: 8

- Number of page views from 12 NAI Team sites.
- Does not include use from other team ~140 team institutions.
- Does not include member use from home, other sites.

- Title of Presentation

## NAI Member Targeted Webpage Usage (May, 2007)

- Member Targeted Webpage Usage (page views, May 2007)
- Team websites/Annual Reports- 10,429
- Newsletter – 4,949
- Seminar Series Archive- 3,463
- Research Archive- 532
- Funding Opportunities- 488
- Events Calendar- 305
- Handbook- 175
- Executive Council- 168
- Collaborative tools- 48

- Title of Presentation