# Presentation: 071089

## What is CDRP?

- Unique 5-year grant program in Radiation Oncology
-   Addresses cancer disparities in a substantial way
-   Support for human and technical infrastructure
-   Development of trials and partnership
-   Ongoing clinical trials and partnerships
-   Telecommunication - TELESYNERGY®

## Objectives of CDRP

- Increase access to radiation oncology clinical trials.
- Increase the number of clinical and translational scientists studying cancer disparities.
- Development of long-term relationships
- Competitive application for ongoing funding.
- Explore the applications of telemedicine.

## Why Radiation Oncology?

- Involves the specialty in this important national effort.
- A major treatment alternative for those in advanced stages of disease.
- Radiation Research Program experience in:
-  Clinical trials network building;
-  Construction and maintenance of partnerships;
-  Applying telemedicine to clinical research settings.
- IT nature makes the specialty more receptive to field training approaches and network arrangements.

## Cancer Disparities Research Partnerships Program

- Awardee

- Telesynergy®

- Partner

- Patient
- Navigator

- Patient

## Populations

- _Populations_
- 	African Americans, American Indians, Asians, Hispanics/Latinos, native Alaskans, Pacific Islanders, and those of low socioeconomic status.
- _Institutions_:
- Up-to-date facilities and staff expertise;
- % of one or more of the populations served is greater than the state average and;
- A greater cancer incidence and/or mortality than the national average.

- Target Populations and Institutions

## NCI-designated Cancer Centers

- RTOG participating institutions
- Other NCI-sponsored cooperative group participating institutions
- By end of 1st year – Submission and approval of detailed Partnership Plan.
- By end of 2nd year – Full implementation of Partnership Plan.

- Partner & Plan

## Submission of Pilot Clinical Trials with Application

- Year 1:
- Build Clinical Trials Infrastructure
- Define Partner Role
- Refine Clinical Trials
- IRB Approval
- Year 2:
- Begin accrual of patients onto clinical trials

- Clinical Trials

##    Some Key CDRP Metrics

-  “significant” increase in the number of all patients on study at the end of 5 years.
- The provision of stage appropriate therapy.
- Establishment of additional multi-modality clinics.
- Number of papers and abstracts (co)authored by physicians.
- The health and activity of the institution’s long-term affiliation with a Cooperative Group, Cancer Center and NCI.
- Ultimate Success: Obtaining ongoing grant funding

## CDRP Funding Areas

**Specialized Infrastructure** (Restricted Funds)
-  telemedicine/teleconferencing
-  networking/communication expenses
-  clinical trials data system (NCI Expense)
**Administrative Core**
-  equipment, supplies, administrative support personnel
-  partnership funding
**Developmental Core**
-  research projects
-  support for data management and research nursing
-  training and education
-  outreach/trials recruitment

## CDRP Timeline

- _Year             1             2             3             4             5_

- Baseline Metrics

- Hire/Train
- Personnel

- Acquire/Install
- TELESYNERGY®

- Select Clinical Trials
- IRB Approval

- Clinical Trials Accrual

- TELESYNERGY Applications

- Consultation/ Advice from Radiation Oncology Sciences Program

- Select and Define
- Primary Partner

- Develop Long-term Affiliation with Partner

- Database
- Implementation

- Results/Performance Measured By CDRP Metrics

- Final Report

- Obtain Long-term Funding

- Evaluation of Prog.
- by NCI

- Cancer Disparities Research Partnerships
- Award Recipients

- _1__st__ Round of Awards (2002)_
- Daniel Petereit, MD
- Rapid City Regional Hospital
- Cancer Care Institute
- Rapid City, SD
- Yadvindera Bains, MD
- Mercy Health Center
- Sanchez Cancer Center
- Laredo, TX

- _2__nd__ Round of Awards (2003)_
- Singing River Hospital        New Hanover Medical Center
- Pascagoula, Mississippi      Wilmington, North Carolina
- Raymond Wynn, MD          Patrick McGuire, MD
- Daniel Freeman Memorial Hospital
- Inglewood, California
- Michael Steinberg, MD
- UPMC-McKeesport Hospital
- McKeesport, Pennsylvania
- Dwight Heron, MD

- CDRP Grant Required Meetings

-  Program Steering Committee (PSC) - Two
- “...review, resolve any operation or implementation issues, or propose recommendations to changing program priorities.”
-  PI, Partner Co-PI, Prog. Scientist
-  April 30, 2004 – Denver, CO
- TCon Using TELESYNERGY®
-  Program Advisory Committee (PAC) - One
- “...provide advice in the guidance and direction of the CDRP program.”
- 3 National Experts, Prog. Director
-  CDRP Annual Mtg. – Wash. D.C. - One
- PI’s, PAC members, Program Scientist, Advocates