BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 354147

## U.S. Department of EnergyOffice of ScienceOffice of Biological & Environmental ResearchSupport for Structural Biology at SynchrotronsPresentation for the Protein SocietyJuly 26, 1999Roland F. Hirsch

## MISSION IN STRUCTURAL MOLECULAR BIOLOGY

- OBER has for 50+ years been responsible for research on health effects of radiation—this research has become more and more oriented to molecular understanding of health effects
- OBER structural biology program serves as an interface between developers of major user facilities and the biomedical research community
- OBER is guided by formal and informal input from the structural biology community:
- Advisory committee reports
- BioSync reports
- Synchrotron user groups
- Professional society recommendations

## PROGRAM ACTIVITIES DURING THE 1990S

- Funded new stations for structural biology at all DOE synchrotrons
- Funded laboratory/office space for structural biology users at all DOE synchrotrons
- Supported detector research leading to two commercially successful CCD designs (Princeton/Cornell and Argonne) for crystallography
- Upgraded computer systems at NSLS and SSRL_x0008_ for optimum management and transfer of large amounts of data by visiting scientists
- Increased funding of beamline operations from $1 million to $7 million annually

## CURRENT FUNDING OF STRUCTURAL BIOLOGY

- Facility Development—$3 million*
- Facility Operation—$8 million
- Facility Equipment Upgrades—$1.5 million
- Instrumentation Research—$2 million
- Biological Research—$7 million
- Computational Structural Biology—$3.5 million
- Database Development and Operation—$1 million
** Primarily neutron facility development in Fiscal Year 1999*

## PLANS FOR THE FUTURE

*Near term:*
- Maintain full operating support for existing OBER beamlines at the four doe synchrotrons, in coordination with other agencies
- Provide adequate funding for equipment replacement/upgrading ($250,000/beamline/year)
- Sponsor research into next generation of detectors
*Long term*:
- Develop additional beamlines as warranted by community needs
- Evaluate new technologies proposed by physics community for relevance to experimental structural molecular biology
# Presentation: 798436

## SPL Demonstration

**June 4, 2004**

## Who is FCG?

## Who is FCG?

**Who is FCG?**

***A leading provider of consulting, technology, applied research and outsourcing services to the life sciences and healthcare industries***

**Over 20 years in business serving life sciences and healthcare**
**Operations in North America, Europe and Asia**
**One of the Top 50 Management Consulting Firms in the world* and the only one serving life sciences and healthcare****exclusively  ****Kennedy Information*
**Strong balance sheet and no debt**

**Consulting**
**10%**

**Technology****& Integration****Services**
**41%**

**Outsourcing****Services**
**39%**

**Other**
**10%**

## FCG Services

***Our services and methods have been developed and honed in on literally thousands of engagements.***

**FCG Services**

**Technology **

- Enterprise Architecture
- Enterprise Integration
- Enterprise Technology
- Enterprise Portal Development
- Messaging Services Optimization
- Staff Augmentation Services

**Consulting**

- Business & Clinical Process Improvement
- Strategic Information Planning
- Revenue Optimization
- Systems Selection & Implementation
- Regulatory Compliance

**Outsourcing**

- Assessment & Due Diligence
- Discrete IT Outsourcing
- Full IT Outsourcing
- Business Process Outsourcing

**Emerging ****Practices**

- Applied Research
- Industry Surveys
- Publications

- World WideHealth Care

## First in Life Sciences

**First in Life Sciences**

**Consulting Services**
- IM Strategy
- Business Process Consulting
- Regulatory Compliance
- Performance Improvement
**Technology Services**** **
- Software Design, Development, and Testing
- System Implementation and Integration
- Training
- Computer Systems Validation
- FirstDocTM Solution Suite
**Outsourcing and Staffing Services**** **
- Full Outsourcing
- Discrete Outsourcing
- Application Hosting
- Staff Augmentation

## Tools Used in FCG SPL Submission

**Content Management**
- Documentum
- FirstDoc R&D with optional Labeling Module
**XML Authoring Environment**
- Arbortext’s EPIC
**Publishing**
- Arbortext’s E3

## From Component Library ...

- DTD’s and Schema’s

_**Illustrative**_

**Publish**

## ... and Impact Assessment Example

**Component**
**Library**

_**Illustrative**_

## Additional Information

**Contacts – United States**
- Greg Kalten
- _[gkalten@fcg.com](mailto:gkalten@fcg.com)_
- 610-989-7051
- Sarah Powell
- _[spowell@fcg.com](mailto:spowell@fcg.com)_
- 610-989-7872
**Contacts - Europe**
- Romuald Braun
- _[rbraun@fcg.com](mailto:rbraun@fcg.com)_
- +49 171 4930350
**Company Information**
- _[http://lifesciences.fcg.com](http://lifesciences.fcg.com/)_
# Presentation: 704948

## Northeastern Forest Soils ConferenceJuly 18-21, 2005

- Northeastern Forest Soils ConferenceJuly 18-21, 2005

- Join us in wonderful West Virginia for the 2005 Northeastern Forest Soils Conference!
**Where:** Earl Ray Tomblin Convention Center, and surrounding areas
**When:** July 18 (4:00 p.m.) to July 21 (12 p.m.), 2005
- Concurrent with the summer meeting of the West Virginia Association of Professional Soil Scientists (WVAPSS)

- Program Description
- July 18  7 p.m. Introduction to West Virginia soils, forests and issues
- July 19 Visit reclaimed mines to evaluate soil  development, restoration success, and learn about research on soil biology.
- 	WVAPSS Business meeting 7 p.m.
- July 20 View forests experiencing repeated fire and evaluate effects on soil development.  Also, an afternoon workshop on collecting soil monoliths
- 	Evening conversation with “Devil” Anse Hatfield.
- July 21 visit to an active mine and discuss soil development, reforestation and other research. Workshop ends at noon.

**Lodging **
- You will need to make your own reservations.  Here are suggestions that are very close to the Conference Center:
- A block of rooms has been reserved at the Best Western Logan Inn  ($75.60 for double rooms). Please id yourself as part of the US Forest Service event. (866-700-7293 toll free). Please make reservations before June 27, 2005.
- Chief Logan State Park : camping$20 /site (304-792-7125) www.chiefloganstatepark.com
- Aracoma Hotel , Logan, WV (304-752-1000)
- The Manor House B&B, Logan, WV (304-752-5824)

**Registration **
- We are still negotiating registration costs, but they will run approximately $150-175 per person, or $60 for a single day.  Registration fees include meals (Monday evening through Thursday breakfast) breaks, evening programs, and field tour costs.
- Registration materials will follow shortly.
# Presentation: 278824

## Airborne Volcanic Ash:  Perspectives, Challenges and Opportunities

*“**Where America’s Climate and Weather Services Begin”*

- Louis W. Uccellini
- Director, NCEP
- 2nd International Conference on Volcanic Ash and Aviation Safety
- June 21, 2004

## Biggest Service Delivery Challenge

- Observations
- Model Prediction
- Product Delivery

- Goal:  “5 minutes from detection to warning”

-   Basic components of Volcanic Ash detection and   prediction services

## Need more accurate and higher resolution data

- Observations:  Principally Satellites for Global Coverage

- Need higher temporal resolution and global coverage (GEO and LEO)
- Need faster delivery and processing of data

**Current Goes**

**Future Goes R**

**Goes 10**

**MODIS**

**Processing the data in a timely fashion will constitute a major**
**challenge  in meeting 5 minute goal. **
**Is it possible for either LEO or GEO?**

## Model Prediction

|  | NOW
VAFTAD | August
HYSPLIT* | Future
HYSPLIT* |
| --- | --- | --- | --- |
| Initialization
(Source) | Point | Point | Point or area |
| Time step (minimum eruption duration) | 1 hour | Dependent on gridsize and wind speed; ~ 15 min GFS;
6 min Eta  | No change  |
| Meteorology Resolution | 190 km | 1 degree GFS
12 km Eta (CONUS)  | Half-degree GFS
45 km Eta North Pacific  |
| Dispersion Resolution | 1 deg | User-set; defaults to 0.25 degrees  | No change  |

- Timing for model delivery is critical for flight planning purposes,
- But not relevant to the “5 minutes from detection to warning” goal

- * As configured for Volcanic Ash Dispersion

## Product Delivery

- Another major challenge facing the service providers in meeting 5 minute goal
- Currently takes 20-25 minute to assess situation and produce products after detection
- Points to possible need for automation – but at what cost to quality control?
# Presentation: 658454

- LHC IRQ Interconnect Engineering Design ReviewJanuary 29, 2002T. Page - Fermilab

## Topics

- Interconnect Kit
- Automatic Welding Clearances
- Shield Line Bellows Pressure Test

## Interconnects

## IC Q1-Q2

## IC Q2-Q3

## Interconnect Kit

- Absorber (T.Nicol).
- Pipes with integrated bellows.
- Pipe supports.
- Bellows protectors.
- Weld rings.
- Shield bridge.
- MLI blanket.
- Outer vacuum sleeve.

## Interconnect pipe with integrated bellows

## Hx Outer Bellows

- Added Hx Outer Bellows

## Helium Pipe Layout

## Pipe Supports

## Bellows Protector

## Interconnect - Welded Joint

## Shield Bridge – IC Q1-Q2

## Shield Bridge

- Fixed End

- Free End

## Shield Bridge

## Outer Vacuum Sleeve

- CERN Bellows
- LHCQBB_A0030

## Vacuum Vessel Bellows

- IC Q1-Q2 and IC Q2-Q3 will use the CERN Bellows.
- Drawing No. LHCQBB_A0030
- Bellows length:  1130 mm
- A special bellows is needed for the Q3 to Feedbox Interconnect.
- Interconnect Length: 510 mm
- Bellows Length: 540 mm
- Modify CERN Bellows

## Weld Clearances

## Automatic Welding Clearances

- (2) Locations where automatic welder will be difficult.
- Cold mass pipe flanges around BPM.
- Hx inner corrugated pipe flange.

## Automatic Welding Clearances - BPM

## Automatic Welding Clearances - BPM

## Automatic Welding Clearances – Hx Inner

## Automatic Welding Clearances – Hx Inner 

## Shield Line Pressure Test

- Full Scale Test
- Bellows Internal Sleeves
- Test Pressure: 400 psi (hydrostatic)

## Shield Line Bellows Cross Section

## Test Setup

## Test Pressure

## Bellows Squirm
# Presentation: 924140

## SSG-WI Planning:Two Time Frames

- 5 Years Out (2008)
- Purpose is to identify uneconomic congestion so that sub-regional entities can develop fixes. One scenario was studied; only generation well under construction.
- 10 Years Out (2013)
- Purpose – To provide Energy Policy decision makers with insights into the transmission impacts of their decisions. Three generation development scenarios were studied (coal, gas, and renewable)

***Seams Steering Group of the Western Interconnection***

## Results Summary 2008

- Existing WECC Transmission Costs
- WECC 2008 Case shows some bottle-necked inexpensive resources - ~$110 million VOM savings, and ~$600 million net benefit
- Resource Development
- New resources are mostly gas-fired CCCTs
- Capacity by fuel type is shifting toward gas, the % change in energy is greater than the rate of capacity increase
- Total VOM Cost Estimates
- More sensitive to gas scenario than hydro scenario
- In 2008, for every $1/MMbtu change in gas price, fuel costs in the Western Interconnection change ~$2 billion

***Seams Steering Group of the Western Interconnection***

## Slide 3

## Slide 4

## Slide 5

## SSG-WI Study Conclusions

***Seams Steering Group of the Western Interconnection***

- Gas resources require less new transmission to develop
- Resources at remote areas require more transmission and longer time
- Transmission additions, common to all three scenarios, were designed to relieve congestion seen in 2008 and 2013
- Emphasis on reliability to be addressed in the sub-regional process as a necessity
- All scenario additions show to be cost effective
- Other supportive benefits from building transmission:
- Loss savings benefits
- lost time for maintenance
- Symbiotic effects of transmission paving the way for more opportunities (i.e. wind developments in Montana, Coal in the eastern states of WECC)
- There are areas on the grid that will be congested in the near future and solutions should be investigated in sub regional forums

## Background map courtesy of Western Electricity Coordinating Council

**Background map courtesy of Western Electricity Coordinating Council**

## Slide 8

## 2013 Incremental

- JB

- Snake

- CHB

- Colstrip

- Alberta

- WA

- Oregon

- MT

- ID

- Utah

- WY

- Colorado

- Mexico

- AZ

- NM

- Snake

- Oregon

- Alberta

- WA

- MT

- Colstrip

- ID

- JB

- Utah

- WY

- Colorado

- CHB

- Mexico

- AZ

- NM

**2013 Incremental**

**Renewables**

**Total **

**MWs **

**= 66,793**

**On Existing Transmission System**

- JB

- Colstrip

- Alberta

- WA

- Oregon

- MT

- Snake

- ID

- Utah

- WY

- Colorado

- CHB

- Mexico

- AZ

- NM

## Path Expansion values 

**Path Expansion values **
**The Gas Scenario has the lowest Expansion Values as the VOM differences between CCCTs in different areas tend to be low.**
**The Renewable Scenario has more remote low cost generators and higher Expansion Values.**
**The Coal Scenario has the highest Expansion Values, due to the quantity of remote MWhs trying to move.**
# Presentation: 143342

## Searching for Silicate Bioweathering

- <date/time>

**Searching for Silicate Bioweathering**
** ****on Earth and Mars**

- _Martin Fisk, Oregon State University_
- _Michael Storrie-Lombardi, Kinohi Institute_
- contributors
- Radu Popa, Portland State University
- Olivia Mason, Oregon State University
- Ed Vicenzi, Smithsonian Institution

## Slide 2

## Slide 3

## Slide 4

## Probabilistic Classification of Biotic Alteration in Basalts

- Elemental Abundance Signatures for Abiotic & Biotic Alteration of Ocean Basalts
- [Na, Mg, Al, Si, P, Cl, K, Ca, Ti, Mn, & Fe]

*Storrie-Lombardi, M. C. and Fisk, M. R. (2004) Elemental abundances in sub-ocean basalt glass and secondary minerals: evidence of biotic and abiotic alteration Geochem., Geophys., and Geosys. 5 (10), doi:10.1029/2004GC000755.*

- PCA

- ANN

***(Sans Expert)***

## Hawaiian HSDP Archaea

## Slide 7

## Fisk, M.R, Popa, R., Mason, O.U., Storrie-Lombardi, M.C., and Vicenzi, E.

- 2006, Iron-Magnesium Silicate Bioweathering on Earth (and Mars?),
- Astrobiology, 6 (1), p. 48-68.

## Nakhla

- Observations in a
- Martian Meteorite

## Why Choose an Ancient Igneous Rock Site?

- Provides information on earliest volcanism on the planet.
- Provides a record to test the hypothesis of early aqueous alteration.
- Igneous rocks preserve evidence of life for billions of years.
- Biosignature in igneous rocks can incorporate but do not depend on the presence of classical organic constituents [ H, C, O, N, P].
-  Biosignatures in igneous rocks are amenable to automated pattern recognition techniques.
- Igneous rock sites are dry and comply with planetary protection constraints.
- Multiple sites exist (many already well-surveyed) exhibiting low altitude, low latitude, minimal slope, and minimal wind characteristics.

## Ideal Igneous Site

- Mandatory
- Exposed Noachian igneous rocks.
- Excellent if
- Prolonged exposure to water
- Dry ever since for preservation.
- Ideally
- “Go to” availability of sulfates and layered terrain
- And of course
- Surveyed by MOC, MOLA, TES, THEMIS, HSRC, and OMEGA and targeted by MRO/CRISM.
- Optimize engineering constraints for wind, altitude, latitude, and slope.

## What Site?

- 						(km)
- NE Syrtis Major 	10oN 	70oE 		0.5-1.5		Harvey
- Nili Fossae 		22oN 	75oE 		-0.6		 Mustard
- Marwth Vallis 	22.3oN	343.5oE 	-2		Bibring
- Eos Chasma		10.9oS	321.7oE	-4.1		Hamilton

***What Site?***

## Slide 13
# Presentation: 476432

##   PMDB

** **** ****PMDB**

**Personal Safety Skills**** **

**VIDEO IV**

## LEVELS OF STRESS

| Stress Level | Staff Action |
| --- | --- |
| Moderate Stress | Verbal Intervention |
| Severe Stress | Limit Setting |
| Panic | Personal Safety Skills or Therapeutic Containment |
| Tension Reduction | Therapeutic Rapport |

## PERSONAL SAFETY SKILLS

**Personal Space**
**Different Ways **
**	****Someone May Harm Us**
**Escape Techniques – A Plan of Escape, Rather than Instinctively Striking Back**

## EXERCISES

**Walk up to your partner and stand nose to nose until told to stop.**
**Walk up to your partner and stand in the supportive stance outside of the **
**	****patient’s striking distance.**
**Punch at your partner's nose **
**	****stopping short of contact.**
**Practice blocking punch.**
**Show grabs**

**EXERCISES**

## GRABS

**2.  Double wrist grab**
**3.  Two hands grabbing one wrist**
**4.  Wrist grab with startle reflex - Demo Only**
**5.  Choke (front & rear)**
**6.  Hair pull (front & rear)**
**7.  Kick**
**8.  Death Grip (Headlock) - Demo Only**

**GRABS**

## PMDB

**Personal Safety Skills**** **

**PMDB**
# Presentation: 322616

## Charge to the Breakout GroupsPBARC Workshop

**Molly Kretsch**
**Acting PWA Associate Area Director**
**May 28, 2008**

## Purpose of the Breakout Sessions:

- To listen to you
- To learn from you
- Synthesize the information

## Agenda: Remainder of the Today

- 1:30	Convene into Breakout Groups 		(Session #1)
- 3:30	Break
- 4:00	Reconvene in Plenary Session -- 		Reports from Breakout Groups
- 5:00	Adjourn for the Day

## Breakout group process:

- 1.       Introductions – record names of group members
- 2.       Ground rules, process, timeline, product
- 3.       Group selects a reporter (stakeholder or customer)
- 4.       Brainstorming stakeholders and customers.  ARS 	   	    scientists to listen/clarify technical concerns.
- 5.       Prioritize research needs as utmost important, very 	    important, or important.
- 6.       Report preparation
- 7.	    Presentation by the reporter at the General Session

## Ground Rules

- One speaker at a time
- All ideas are welcome without criticism
- No interrupting
- Everyone participates

## Questions for Breakout Session #1

- What crop and cropping systems are the future of agriculture in Hawaii and the Pacific Basin?
- What are the key constraints to future agricultural sustainability, productivity and profitability from a National perspective?
- What are the current and future regulatory research needs for APHIS and other action agencies that PBARC could address?
- Taking these factors into account, along with the ARS National Programs as a backdrop, what are the future research needs that PBARC is uniquely positioned to address?

## Questions for Breakout Session #2:

- Are there additional research needs that should be added to the questions addressed in Session #1?
- Prioritize the identified research needs into utmost importance, very important, and important taking into consideration PBARC’s unique strengths.
- Develop a proposed vision statement for PBARC that would capture these priorities.

## Breakout Group Assignments:

***Green Group  – Room 1 ***
- Discussion Facilitator:  Peter Bretting
- Recorders:  Lisa Keith, Marisa Wall
***Blue Group  – Right-side of Main Room***
- Discussion Facilitator:  Sally Schneider
- Recorder: Robert Hollingsworth
***Purple Group  – Room 2***
- Discussion Facilitator:  Dan Strickman
- Recorders:  Stella Chang and Grant McQuate
***Red Group  –  Left-side of Main Room ***
- Discussion Facilitator:  Molly Kretsch
- Recorders:  Peter Follet, Tracie Matsumoto

- Mahalo!
# Presentation: 685816

## Chronic Liver DiseaseDeaths, 2000

|  | Rank | % Total
Deaths | Death
Rate |
| --- | --- | --- | --- |
| All US | 12 | 1.1 | 9.6 |
| Black | 14 | 1.0 | 9.5 |
| Hispanic | 6 | 3.0 | 15.7 |
| AI/AN | 6 | 4.7 | 28.6 |

**Notes:**
Now let’s consider hepatitis C. Since chronic hepatitis C infection is more difficult to identify than acute cases of hepatitis A or B, we often use surrogate measures of its impact, such as deaths from chronic liver disease. Evidence that chronic liver disease morbidity and mortality vary by race is abundant. I obtained these year 2000 age-adjusted death rates from chronic liver disease and cirrhosis from the National Center for Health Statistics. They show that as measured by either rank order, percentage of total deaths, or death rate, the impact of chronic liver disease is particularly large for American Indians and Hispanics. Of particular note is that the death rate in Indians is around three times higher than the national average. Some of this difference may be explained by differences in risk factors such as alcohol use, but these data still compel us to take a careful look at race and ethnicity and their effects on patterns of viral hepatitis. 

## Years of Potential Life Lost (YPLL) 

|  | YPLL
AI/AN | YPLL
US | Ratio
AI/AN:US |
| --- | --- | --- | --- |
| Heart disease | 1244 | 1271 | 1.0 |
| Cerebrovascular disease | 239 | 226 | 1.1 |
| Diabetes | 367 | 181 | 2.0 |
| Chronic liver disease (CLD) | 648 | 166 | 3.9 |

**Notes:**
The answer is made clear when we consider data of the type presented by Dr. Cheek. The fact is, liver disease has a huge impact in Indian communities. Let’s look at som edata from the National Center for Health Statistics from 2000. The first two columns present years of potential life lost before age 75 per 100,000 population in American Indians and Alaska natives as well as the YPLL in the US as a whole. The last column is the ratio between YPLL in natives and YPLL in the US for the given condition. For heart disease, the ratio is 1.0. For cerebrovascular disease, the ratio is 1.1. For diabetes, the ratio is 2.0. For chronic liver disease, the ratio is 3.9. I will say this again: the impact of death from chronic liver disease is almost 4 times higher in Indian communities than in the country as a whole. Liver disease in Natives, then, deserves the same attention and financial support as other conditions, such as diabetes, to which IHS has devoted considerable resources.
# Presentation: 526713

## Electrical Systems Efficiency

**Electrical Systems Efficiency**

- Bill Tschudi, LBNLWFTschudi@lbl.gov

## Electrical Systems Efficiency

- Electrical distribution systems
- Lighting
- Standby generation
- On-site generation

## Electrical Distribution		

- Every power conversion (AC  DC, DC  AC, AC  AC) loses some power and creates heat
- Distributing higher voltage is more efficient and saves capital cost (wire size is smaller)
- Uninterruptible power supplies (UPS’s) efficiency varies
-  Power supplies in IT equipment efficiency varies

## Overall Power Use in Data Centers

- Courtesy of Michael Patterson, Intel Corporation

## Data Center Power Conversions

**Data Center Power Conversions**

**Power Distribution Unit (PDU)**

**Server**

**Uninterruptible Power Supply (UPS)**

- AC

- DC

- AC

- DC

## UPS Factory Measurements 

**UPS Factory Measurements**** **

**Typical Operation**

## Measured Power Supply Efficiency

**Measured Power Supply Efficiency**

- Typical operation

## Typical AC Distribution Today

- 480 Volt AC

## Facility-Level DC Distribution

- 380V.DC

- 480 Volt AC

## Rack-Level DC Distribution

- 480 Volt AC

##  AC System Loss Compared to DC

- 7-7.3% measured improvement

- 2-5% measured improvement

**Rotary UPS**

## Video of DC Demonstration 

**Video of DC Demonstration **
**is Available**

## Data Center Lighting

- Lights are on and nobody’s home
- Lighting controls are well proven – why not use them?
- Small benefit but easy to accomplish – also saves HVAC energy
- DC lighting would compliment DC distribution

## Standby Generation Loss

**Standby Generation Loss**

- Several load sources
- Heaters
- Battery chargers
- Transfer switches
- Fuel management systems
- Heaters (many operating hours) use more electricity than the generator will ever produce (few operating hours)
- Opportunity may be to reduce or eliminate heating, batteries, and chargers

## Standby Generator Heater

## On-Site Generation

- On-site generation with utility back-up
- Thermal host required for combined heat and power
- Absorption or adsorption chillers
- Other campus use
- Renewable sources (future)
- Fuel cells
- Solar
- Wind

## Take Aways

- Distributing higher voltage (AC or DC) is more efficient
- Electrical power conversions are inefficient
- Highly efficient UPS’s should be specified
- Highly efficient IT equipment power supplies should be specified
- Lighting is a small but low hanging opportunity
- Standby generation losses can be minimized
- On-site generation can improve reliability and efficiency

## 

website: http://hightech.lbl.gov/datacenters/

**website: **http://hightech.lbl.gov/datacenters/
# Presentation: 484281

## Hydrogen and Ultra-High Vacuum

- Jefferson Lab
- Photo-Electron Gun

-  Baked Stainless chamber
-  Base pressure ~1e-11 Torr
-  Pumped with Ion and NEG pumps
-  Hydrogen dominates residual gas

## Photocathode Lifetime

- Cathode Degradation

- >15.0E-11 Torr

- ~5.0E-11 Torr

- ~2.5E-11 Torr

- Lifetime vs. Pressure

- J. Grames, Jefferson Lab

## Vacuum Improvements

- Chamber material
- Al, 304SS, 316L SS
- Coatings
- TiN, SiO2, Getter
- Pump Speed measurements at UHV

## Conclusions

- Vacuum quality directly affects photocathode lifetime
- Hydrogen is the primary residual gas in UHV/XHV systems
- We are researching diffusion barriers and pumping for UHV

## Slide 5
# Presentation: 687225

## Online Calibration of VLPC chips

- Calibration event
- All fibers illuminated with  LED chips
- All SVX II chips connected to VLPC chips read out
- Can we take calibration events during the store ?
- Yes, if time used less than 0.1 % of total time

## Data Flow

- Analog signals from VLPC chips flow to SVX II chips on electronic boards on the top of cassettes
- Digitized data from SVX II chips fed via fiber links to VRB modules-VME Readout Buffer modules
- 8 SVX II chips readout serially into VRB modules-data stream
- all streams get into VRB modules in parallel

- VRB module

- streams of data
**1 stream also into monitoring buffer**

**8 SVX chips**

## Data Flow

- VME crate
- Processor-reads in monitoring buffer through a 1394 bus
- VRB modules, 10 in a crate
- monitoring buffer = 1/8 of data buffer
- Three VME crates for VLPC data
- Data to Data cable from VME bus

**VME ****crate**

- V
- R
- B

**VME ****crate**

**VME ****crate**

**Data cable to Level 3,    48 Mbytes/s**

**Processor**

**Monitoring data, 1394 bus**

- Data from VME bus to Level 3

## SVX initialization

- For calibration event *Read All Channels *bit set to 1 has too be clocked into SVX
- This can be done only by executing full initialization of SVX, which constitutes of clocking in **serially** **of 190 bits**.
- Eight SVX chips are daisy chained and the internal registers are download in sequential order
- 1553 :1.3 s/bit
- SVX II manual: 19 ns/bit

- Chip #1

- 190
- bits

- Chip #8

- 190
- bits

-       8190 bits
- downloaded  serially
-        by 1553

- 190
- bits

## Calibration with Embedded Processors*

- Time to read out calibration event with embedded processors
- If calibration events use 0.1 % of time then:

**Frequency of Calibration Events:**
** ****112/h(1553)          4000/h(53 MHz)**

- *Nobody works on driver for 1394 bus

## Calibration in Level 3

- Size of calibration event: 400kbytes
- Speed on data cable:                48 Mbytes/s
- Read out time for data:             10 ms (400kbytes/48 Mbytes/s)
- Total time for calibration event: 12 ms             ( 2 ms for initialization of SVX)

- 100000 VLPC • 2bytes/hit • 2 for unused SVX channels

**Frequency of Calibration Events: **
**                   ****300/hour**

## Sampling Calibration EventEight VLPC Chips Only

- Only eight VLPC chips reading out axial fibers calibrated
- Two SVX chips to which these VLPC chips are connected are permanently in *Read All channels* mode
- This adds 0.5kbytes to each data event     (2•128 •2) increasing event size (74240 fibers •0.02 occupancy •2 ) by 17%
- With Embedded Processor total time for calibration event : 48 s
- VME bus could be used for read out
**With Level 3** total time is  58 s
- Size of calibration event: 2kbytes (960 fibers in one wedge •2)-**One wedge illuminated by LED**
- Time for transfer of data : 50 s
- Frequency of calibration events: 3600s/hour/50000 s

**Frequency of Calibration Events: **
**               ****60000/hour**
# Presentation: 548841

## Information Sharing Java Interface for Storm Targeted Radar Wind Retrievals at Very High Resolution

- PI:  Qin Xu, NSSL
- Co-PI: Pengfei Zhang, CIMMS
- Co-PI: Kevin Kelleher, NSSL
- Co-PI: Don Burgess, CIMMS

**COL/CE/08**

- 6/1/05

## High Resolution Storm Targeted Radar Wind Retrieval System

## Real-time Interactive Communication System 

- Real-time Interactive Communication System

- Index Linear Buffer
- Real-time radar data

- Index Linear Buffer Output of
- TVS or Mesocyclone Detection

- Control Linear Buffer
- Interactive Selection of
- Wind Retrieval Para.

- Automatic Trigger of
- Wind Retrieval Process

- The signals in the system are managed
- by RSSD (Remote System Service Daemon).

## Graphic Information Share Interface

- (3) Execute wind retrieval

- (2) Set the parameters

## Developed Features of the System 

- Real-time;
- Graphic selection of domain location;
- Interactive interface and multi-functional display;
- Event driven data manager;
- Automatic target following wind retrieval.
# Presentation: 823441

## Congratulations!!

**You have made it to the end of the day**

## But...before you go

**Recap today’s lectures**
**Discuss some items we did not cover today**
**OIVD updates**

## Questions??

**1.  What is the difference between a Traditional 510(k), an Abbreviated 510(k) and a Special 510(k)?**

**2.  What is needed for a Turbo 510(k) submission?**

**3.  When should you submit a Pre-IDE (protocol review)?**

**4.  What to do if you do not have a classification for your device?**

**5.  Where do you go for CLIA questions or problems?**

## http://www.fda.gov/cdrh/oivd/

## www.fda.gov/cdrh/oivd/guidance/1171.html

## Thank you	

**Any Questions??**

- _[www.fda.gov/cdrh/clia](http://www.fda.gov/cdrh/clia)_
- _[www.fda.gov/cdrh/oivd](http://www.fda.gov/cdrh/oivd)_
# Presentation: 136118

## S. A. David and S. S. Babu 
Metals and Ceramics Division
Oak Ridge National Laboratory
Oak Ridge, TN 37831-6095

http://mjndeweb.ms.ornl.gov/Babu

***Metals and Ceramics Division***
***Oak Ridge National Laboratory***
***Oak Ridge, TN 37831-6095***
***http://mjndeweb.ms.ornl.gov/Babu***

***Trends in Welding Science***

## Outline of the course

***Introduction***
***Weld solidification***
***Non-equilibrium Solidification & Crystallography***
***Details of weld solidification - Transparent metal analog***
***Extension to single crystal nickel base superalloys***
***New welding processes***
***Friction stir welding process***
***Laser assisted arc welding***
***New tools for characterization***
***Computational tools for weld process modeling***

## Interaction of thermal, chemical, electrical and metallurgical processes control the microstructure and properties of welds.

***Therefore, there is a need to develop a science based approach to design new welding processes and materials for optimum performance of welded structures.***

## In this lecture, different research areas will be reviewed.

***Solidification Research***
***Solid State Transformation Research***
***New Welding Processes Research***
***Advanced Characterization Research***
***Computational tools for weld process modeling***
# Presentation: 530382

## Chinese Criminal Justice and IPR-Related Issues

- <date/time>

- Dr. James V. Feinerman
- Associate Dean
- Georgetown University Law Center

## INTRODUCTION 

**Function of Criminal Law in PRC**
**Sources of Criminal Law**
**Kinds of Law** – Formal v. Administrative

## HISTORY 

**Criminal Law through the Ages**
**Communism’s Effect on the Law**
**The Post-1949 Experience **
**The Chinese Legal Profession**

## COURT ORGANIZATION

**Functions of Chinese Courts**
**Jurisdiction of Courts**
**The Structure of Courts**
**Basic People’s Courts** (Trial)
**Intermediate People’s Courts (Appeals)**
**Provincial High Courts**
- Supreme People’s Court
**Alternative Dispute Resolution **
**Arbitration and Mediation**

## PROCEDURAL ISSUES (1 of 2)

**Criminal Procedure**
**Pre-trial Proceedings**
**Custody and Detention**
**Arrest**
**Search and Seizure**
**Preliminary Hearings**
**Arraignment**
**Right to a Speedy Trial**

## PROCEDURAL ISSUES (2 of 2)

**Criminal Procedure (cont.)**
**Criminal Trials **
**Piecemeal “Trial” **
**NO Trial by Jury **
**“****Fair and Public” Trial **
**Prosecution – People’s Procuratorates**
**Sentencing**
**Appeal and Habeas Corpus **
**Punishment and Correction**

## Criminal IPR Penalties (1 of 2)

- Trademark (arts. 213-215)
- Imprisonment or criminal detention of 3 years or less
- Fine – may be separate or simultaneous
- More serious cases – 3 to 7 years’ imprisonment AND fine
**Patent (art. 216)****	**
- Imprisonment or criminal detention of 3 years or less
- Fine – may be separate or simultaneous
**Amendments**

## Criminal IPR Penalties (2 of 2)

- Copyright and Trade Secrets (arts. 217-219)
**Similar Penalties **
**Expansive definition of circumstances (copying, distributing, producing written and audio or video works)**
**Unit Liability (art. 220)****	**
- Imprisonment or criminal detention of 3 years or less for “person in charge”
- Fine for unit to pay

## The Campaign Trail in China

- China’s Recent Vows to Crack Down
**Sept. 2004 – Aug. 2005**
**National IPR Protection Working Group**
**Regional and Product Focus**
**Beijing, Shanghai and Tianjian**
**12 other provinces and autonomous regions**
**Pirated CDs and DVDs and Trademark Infringement**
**Foodstuffs, Drugs and Public-Health Related agricultural materials**

## Recent Statistics

**1,710 IPR Cases since 2000**
**Up 56.42 percent from same period in previous four years **
**Crackdown related to WTO accession**
**2,462 arrests in 1,539 criminal cases**
**2,491 person in 1,500 cases were initially prosecuted**

## Recent Case – Progress?

- Huawei Technologies
- Sued Former Employees
- 3 Defendants given 2-3 year prison terms and fines of 50,000 yuan (US $6,024) EACH
- Founded a company making optical network products similar to those of their former employer (sold technology and some assets for 2 million yuan AND shares worth US $15 million!)
- Why Progress?
- Wholly domestic – no outside pressure
- Realization of genuine economic harm to domestic actors in the economy
# Presentation: 422888

## What Do Workforce Issues Have To Do With Patient Safety?

**Jack Needleman, Ph.D. **
**Assistant Professor of Economics and Health Policy **
**Department of Health Policy and Management**
**Harvard School of Public Health **
**Boston, MA**

## Higher RN staffing was associated with:

- For medical patients:
- Shorter length of stay
- Lower rates of urinary tract infections, shock and cardiac arrest, upper gastrointestinal bleeding, pneumonia, and “failure to rescue”
- For surgical patients:
- Lower rates of “failure to rescue” and urinary tract infections
- Source: Needleman, Buerhaus et al, “Nurse Staffing and Quality of Care in Hospitals,” *NEJM*, May 30, 2002

## Variation in Hospital Staffing

**Variation in Hospital Staffing**

## Estimate of increasing RN staffing from 25th to 75th percentile

## Why these outcomes are important

- Longer length of stay adds to cost, discomfort, may reflect other complications
- Urinary tract infections common
- Failure to rescue deaths among patients with serious complications
- Pneumonia, upper GI bleed, shock/cardiac arrest have risk of death
***These impacts are lower bound estimates of effect of nursing***

## Other research needed

- Quantifying impact of other factors influencing nursing’s impact on patients
- Why staffing varies so much
- Improvements in measures of nursing need of patients
- How to improve hospital nursing work environment

## Other factors potentially influencing nursing’s impact on patient outcomes

- Working conditions
- Nursing organization at unit level
- Organizational culture & climate
- Overtime
- Physical organization of nursing unit
- Technology

## How much would increasing nursing cost

***Rough*** estimate to move from 25th to 75th percentile:
- Change RN/LP mix only:
- $  15/day  (  2% increase)
- Change RN/LP mix and increase hours
- $100/day  (10% increase)
- Estimates need further refinement

## Potential cost offsets of increasing nursing

- To hospital
- Reduced costs of shorter length of stay
- Reduced costs of treating complications
- To patients
- Lost time at hospital
- Avoided death or discomfort
- How to measure willingness to pay or value?

## Why is the association observed with RNs, not LPNs or Aides?

- Not sure.  Possible explanations:
- RNs largest nursing category, most variation
- Preventing these outcomes draws on RN skills
- Most accurately measured
- Don’t draw conclusion that can cut back LPNs or Aides with impunity

## Some implications for policy making

- Nursing matters to patient safety in hospitals
- Efforts to assure adequate nursing are legitimate
- Adequacy needs to be clearly defined
- Possible to monitor nursing sensitive indicators as measures of patient safety in hospitals

## Quality and usefulness of state data

- Used state discharge data sets and state staffing survey data.  Invaluable assets
- Improvements needed:
- Discharge data
- Present on admission coding of secondary diagnoses
- Selected “must report” secondary diagnoses
- Staffing data
- Inpatient/outpatient split
- Aide data
# Presentation: 678627

## Recent work on the MAGIC Ionosphere Modeling Software

*Douglas.Robertson@noaa.gov*

**Recent work on the MAGIC Ionosphere Modeling Software**

## Slide 2

## Slide 3

## Slide 4

## DD ionosphere: reference and tested solutions

**DD ionosphere: reference and tested solutions**
**18 February 2005, 162 km baseline (CHSN-MIO1)**

**Minor geomagnetic**
** ****storm**

-         DD ionosphere: MPGPS model (residuals with respect to reference ionosphere)

## Slide 6

## Slide 7

## Slide 8

## Network geometry

**Network geometry**

**MIO1**

**SOWR**

**CLRE**

**CHSN**

**292**

**162**

**158**

**248**

**247**

**135**

**   ****247-292 km CORS station****     separation**
**   ****135-162 km base-rover distances**
**   ****The network provides****     atmospheric corrections to the****     rover solution**

**Distances in Km**

**N**

## Experiments and test results

**Experiments and test results**

- DD ionospheric correction statistics: *percentage of residuals within *
*predefined limits w.r.t. reference ionosphere*

- 2-4 UTC

- 14-16 UTC

## Slide 11

## Slide 12

## Cors Stations 10/02/05, 817 Stations

## Decimated to One Degree Minimum Spacing, 283 stations

## Present MAGIC Station List, 187 Stations

## Decimated to Two Degree Minimum Spacing, 130 stations

## Decimated to Five Degree Minimum Spacing, 44 stations

## New 1x1 Station Set

- Old Station Set

## Need to be able to download:
A list of stations available for each day, with
Names, with correct lower case
Coordinates
Quality, i.e., residual size, average availability

**A list of stations available for each day, with**
**Names, with correct lower case**
**Coordinates**
**Quality, *****i.e*****., residual size, average availability**

## Real-time ionosphere modeling

## Slide 21

## Conclusions:

- There are four principal areas where GPS ionosphere modeling is susceptible of significant improvements in the foreseeable future:
- Input data
- Model parameterization
- Computer power
- Validation and intercomparison
# Presentation: 165387

## Privilege Project

- Ian Fisk
- GDM Report
- February 8, 2005

- GDM Project Presentation

## Project  Drivers  & Scope

- The primary goal of this phase of the project was to deliver the execution call-out for finer-grained authorization of processing resources
- Generate an extended proxy based on role information stored in VOMS
- Module to parse extended attribute certificates
- Communicate the information to a identity mapping service in a secure manner
- Return the information to the Globus gatekeeper
- Map the user to a specified UID

- GDM Project Presentation

## What we can do with that

- Three possible installation methods
- Do nothing.   In the process of verifying the extended proxies don’t interfere with sites that have not added a callout
- Try not to break anything
- Install basic mappings in GUMS that maps most users to old Grid3 group accounts.    Very coarse mapping for users to perform VO level administration tasks
- Would already make a better system for user analysis
- Use pools of user accounts to map individuals to separate accounts that are maintained for the life of the certificate.    Keep coarse mappings for users to perform VO administration tasks.
- Improve tracking of users and satisfy some sites with problems with the current techniques
- User individual accounts for everyone mapped with GUMS.    Admin accounts for people with extended proxies
- Satisfy all sites with problems regarding group accounts

- GDM Project Presentation

## Project  Milestones

- We are on schedule to role of phase one functionality for the OSG deployment workshop
- End-to-end testing works
- Working on packaging, testing, deployment, and documentation
- Basic binary distributions look good.
- Working on getting into VDT packaging, compilation, and deployment
- This is an on-going program of work
- Storage Interface is close to working
- Intended for dCache SRM
- Should also work for DRM
- Service level authorization is still a goal
- Would be interesting for site security
- Glide-in applications and services

- GDM Project Presentation

## Effort Profile

- Basic Support for deployment support should take about 0.25FTE
- Should decrease as packaging and experience improves
- Development of phase 2 requires about the effort we have

- GDM Project Presentation

## Risks

- Due to the hard work of a lot of folks, we basically have what we wanted for processing
- Need to finish the same basic functionality for storage
- We have to replace Markus Lorch who is going back to Germany
- Markus was a huge asset he’ll be hard to replace
- We tried to meet the needs of US-CMS, US-ATLAS, and OSG.   We could have easily missed SAM-Grid or FermiGrid requirements.

- GDM Project Presentation
# Presentation: 253731

## Radiation Assessment Detector (RAD)

- D.M. Hassler, A. Posner, M. Bullock, S. Rafkin, D. Grinspoon (Southwest Research Institute)
- R.F. Wimmer-Schweingruber, R. Beaujean, S. Burmeister, R. Muller-Mellin, S. Bottcher (Univ. of Kiel)
- G. Reitz (DLR/Koln)
- F. Cucinotta, T. Cleghorn (NASA/JSC)

## Slide 2

## Slide 3

| 
MSL RAD Scientific Objectives
To characterize fully the broad
spectrum of radiation at the
surface of Mars, ...measuring all of the relevant energetic particle species, including secondary neutrons and other particles both created in the atmosphere and the Martian regolith. 
 | Characterize the energetic particle spectrum incident at the surface of Mars, including direct and indirect radiation created in the atmosphere and regolith. |
| --- | --- |
|  | Determine the radiation Dose rate and Equivalent Dose rate for humans on the Martian surface. |
|  | Validate Mars atmospheric transmission models and radiation transport codes. |
|  | Determine the radiation hazard and mutagenic influences to life, past and present, at and beneath the Martian surface. |
|  | Determine the chemical and isotopic effects of energetic particles on the Martian surface and atmosphere. |

## Validating Radiation Transport Codes and Models

- Penetration Depths for Various Energy Particles.

- Secondary Particle Production from Galactic Cosmic Rays

## Atmospheric Shielding at Mars:

**Atmospheric Shielding at Mars:**
- Strong dependence on atmospheric column mass

## Slide 6

## HEND/Odyssey: Global Map of Neutron Albedo of Mars

**HEND/Odyssey: Global Map of Neutron Albedo of Mars**

## RAD Time Resolution Required to Characterize a Solar Particle Event (SPE)

## Astronaut Safety: Determining the Radiation Dose Rate for Humans on Mars

- GCRs produce near-constant background flux of radiation, modulated by solar cycle.
- Composed mostly H+ and He2+, but heavy ions contribute disproportionately to the Dose Equivalent due to their high quality factor, Q. (Wilson et al. 1997)

## Preparation for Human Exploration of Mars: Astronaut Safety Requires Monitoring Certain Particle Species

**Preparation for Human Exploration of Mars:** Astronaut Safety Requires Monitoring Certain Particle Species

## MSL RAD Measurement Capability

## RAD Instrument Overview

- RAD proto-type (top) being tested at Brookhaven National Lab (bottom)

## RAD Species Identification Approach:Distinguish Ion Species using dE/dx vs E method

- Bethe-Bloch Equation:

- Ion Identification:

- substitute *v**2* with:

- Thus:

- Ion kinetic energy deposited per unit length:

## RAD Species Identification uses dE/dx vs E Method

## Slide 15
# Presentation: 284680

## Flight Standards Division

**Western-Pacific Region**** **

- Pacific Aviation Directors Workshop

- Mike McCarthy, Assistant Division Manager
- Ron Waterman, Manager, Technical Standards Branch
- Chris Collins, Manager, Honolulu FSDO

- March 31-April 2, 2008

## Flight Standards

-  8 Regional Offices                 98 Field Offices

## Western-Pacific RegionRegional Office     17 Field Offices

**Fresno (FAT) FSDO**
**Honolulu (HNL) FSDO**
**Las Vegas LAS) FSDO**
**Long Beach (LGB) FSDO**
**Los Angeles (LAX) FSDO**
**Oakland (OAK) FSDO**
**Reno (RNO) FSDO**
**Riverside (RAL) FSDO**
**Sacramento (SAC) FSDO**
**San Diego (SAN) FSDO**
**San Francisco (SFO) CMO**
**San Francisco (SFO) IFO**
**San Jose (SJC) FSDO**
**Scottsdale (SDL) FSDO**
**Singapore (SIN) IFO**
**Van Nuys (VNY) FSDO**

**Western-Pacific Region****Regional Office     17 Field Offices**

## Western-Pacific Region

## Slide 5

## Ron Waterman

**Manager**
**Technical Standards Branch**
**AWP-230**

## Work Functions

**Air Carrier Labor Unrest Issues**
**Air Operator Maintenance Programs**
**Air Operator Certifications**

## Work Functions

**Aging Aircraft Programs**
**Approval of Extended Over Water Operations**
**Authorization of Designated Pilot Examiners**

## Work Functions

**Human Factors**
**International Programs**
**Maintenance Reliability Programs**

## Work Functions

**Maintenance Schools**
**Manned Balloon and Airship Operations**
**Motion Picture and Movie Manuals**

## Work Functions

**Pilot Training Schools**
**Public Use Aircraft**
**Region Aviation Events**

## Work Functions

**Special Flight Authorizations**
**Suspected Unapproved Parts**
**Ultra Light Aircraft**

## All Weather Operations

## All Weather Operations

**Airport Airspace Analysis**
**Comment of Airspace Studies**
**Foreign Instrument Approach Procedures**

## All Weather Operations

**Review Proposed Airspace Changes**
**Special Instrument Approach Procedures**
**Terminal Obstruction Evaluations**

## Chris CollinsManagerHonolulu FSDO

**Honolulu FSDO is located on Lagoon Drive on the east side of the Honolulu International Airport**
**District includes: State of Hawaii, Wake Island, American Samoa, Guam, and the Commonwealth of the Northern Marianas**

## Slide 17

## FSDO Responsibilities

**Surveillance**
**Investigation**
**Certification**

## The HNL FSDO is Responsible for:

**121 Air Carrier Certificates**
**135**
**141**
**Part 91**
**Part 61**

## Surveillance

**Inspectors observe aviation activities**
**Results of most surveillance activity show compliance**
**When non-compliance is discovered, initiate an investigation**

## Investigation     

**Enforcement Action**
**Administrative Action**
**No Action**

**Investigation ****    **

## Certification 

**Pilots, Instructors, Mechanics, Dispatchers**
**Appointment of Designated Examiners**
**Certification of Air Carriers and Operators**

## QUESTIONS?