# Presentation: 153409

## Overall Summary of Progress

- Elaine Z. Francis
- National Program Director, Pesticides and Toxics Research

*EDCs Research Program Mid-Cycle BOSC Review*

- September 18, 2007

## Review of Recommendations & Actions - 1	

- Overall Conclusions
- ‘Introduction’ of draft MYP clarifies what is and is not covered in the EDCs research program
- Strengthening/defining NPD’s role is a work in progress
- Using innovative methods to supplement/ complement EDCs researchers
- Draft document on ORD Senior Managers’ Roles and Responsibilities (August 2007)

## Review of Recommendations & Actions - 2

**Long Term Goal 1 – Provide Underlying Science**
- Leveraging with wildlife toxicity researchers in other ORD programs and other Agencies; improving communication of research results
- Collaborating across ORD programs on cross-species extrapolation and the development of predictive tools for prioritization
- Conducting research toward the development of new risk assessment paradigms – cumulative risk; incorporation of ‘omics into assessments

## Review of Recommendations & Actions - 3

**Long Term Goal 2 – Determine the impact**
- Improving interagency interactions, particularly as related to exposures, and exploring research on pharmaceuticals as environmental EDCs
- Mining of data conducted in other ORD research programs
- Research from epidemiology grantees is closely monitored and PIs will be invited to the next BOSC review

## Review of Recommendations & Actions - 4

**Long Term Goal 2 – Determine the impact**
- Investigating common ground between ecological and human health through case study development, interagency activities, research on cross-species extrapolation and exposure methods’ development
- Playing a role in research and policy developments on ‘omics applications under auspices of EPA’s Office of Science Advisor

## Review of Recommendations & Actions - 5

**Long Term Goal 3 – Support screening and testing program**
- Enhancing our capabilities in the area of bioinformatics
- Made significant progress in completing research to develop/standardize assays for EDSP; all Tier 1 and two Tier 2 assays completed, two Tier 2 assays remain
- Improving communications of research results
- Accomplishments report, bibliography, Appendix in MYP, website

## Collaborators – Academic & Other Research Institutions

- Purdue U
- U of Cincinnati
- Texas A & M U
- U of FL
- Xavier U of LA
- Portland State U
- UC-Davis
- U of GA
- UC-Berkeley
- EOSHI at Rutgers U
- U of NV
- U of WI
- U of NE-Lincoln
- U of MD
- VIMS at the College of W&M

- Georgetown U
- U Mass-Amherst
- UMDNJ
- UNC-Chapel Hill
- U of Rochester
- Harvard U
- Fred Hutchinson Cancer Research Center
- St. Cloud State U
- U of OK
- U of TN-Knoxville
- U of SC-Columbia
- NC State U
- Wye Institute

## Other Collaborators

- US Federal Agencies
- USGS
- USFWS
- DOE
- Through IWGs on ED and PiE
- USDA, FDA, CDC, NIEHS, Smithsonian, NOAA, ATSDR, CPSC, OMB, OSTP, DOD
- Countries/International Organizations
- Dept of Fisheries and Oceans – Canada
- European Union
- Japan
- Organization for Economic Cooperation and Development (OECD)
- World Health Organization (WHO)

- State and City Agencies
- WI Dept of Health & Family Services
- OH EPA
- OH River Valley Water Sanitation Commission (ORSANCO)
- IN Dept of Environ Mgmt
- NM Environ Dept
- CA Water Quality Board
- Metropolitan Water Reclamation District of Greater Chicago
- Denver Metro Sewage District
- Fairfield, OH
- Trinity River Authority
- Water Industry Research Foundations
- Global Water Research Coalition
- AWWARF
- WERF
- PPCPs Industry
- Procter and Gamble

## Next Steps

- Solicit comments on MYP and Accomplishments Report from Program and Regional Offices
- Finalize the MYP and Accomplishments Report
- Finalize development of website
- Convene ORD-OPPTS (and                                 other) senior managers
- Research progress overview
- Confirm/prioritize research                             needs