# Presentation: 155444

## Renewing the Public Private Diabetes Research Partnership

**Cynthia Rice, Director of New Technology Access**
**Juvenile Diabetes Research Foundation**
**10****th**** Congressional District Diabetes Summit**
**October 8, 2007**

## The Costs of Diabetes are Staggering

- Diabetes effects millions of Americans
- More than 20 million Americans have diabetes
- 1 in 3 Americans born in 2000 are expected to develop the disease in their lifetimes
- Diabetes is a leading cause of heart attacks, strokes, amputations, blindness, and kidney failure
- Costs of diabetes are staggering
- $132 billion a year to the nation
- Health costs for people w diabetes are nearly 5 times higher
- 1 in 3 Medicare dollars is spent on people w diabetes

## Life with Diabetes is Very Difficult

- As these families told Rep. Kirk when they met with him in August, living with diabetes is very hard
- Painful glucose tests and insulin injections many times a day
- Middle of the night blood checks
- Lows interfere with sports and other activities
- Threat of seizures and comas
- Threat of complications such as stroke, heart attack, blindness, and kidney failure
- Constant stress – never a vacation

## Strong Public-Private Partnership for Diabetes Research

- Diabetes research a strong public private partnership
- National Institutes of Health (NIH) funds 75% of type 1 diabetes research ($433 million in 2005)
- JDRF funds 25% of type 1 diabetes research ($110 million)

## Public-Private Partnership is Moving Us Closer to A Cure

- This research partnership is making great strides:
- New technologies – Development and evaluation of continuous glucose monitors
- Prevention – Testing promising approaches to prevent or delay type 1 diabetes
- Complications  – Development of new drugs to treat diabetes complications such as diabetic eye disease

## The Promise of Continuous Glucose Monitors (CGM)

- Continuous glucose sensors give patients new tools with which to control glucose
- Continuous readings – see effects of insulin, food, exercise
- Trends – information to ward off highs and lows
- Alarms – alert patient or family member
- New studies validate that continuous glucose sensors enable patients to achieve better control
- 26% more time in target glucose range
- Improved HbA1C, the clinical measure of glucose control

## CGM an Example of the Public- Private Research Partnership

- National Institutes of Health
- Initial scientific research which led to new and better glucose sensing technologies
- Testing of CGM in children
- Companies
- Developed products
- Two now approved by FDA, one awaiting approval
- JDRF
- Clinical trial to gather data needed for health plan reimbursement of CGM

## Critically Important NIH Diabetes Program Set to Expire

- Special Diabetes Program at NIH
- Funds clinical trials with 60,000 patients
- Was created in 1997 and has been renewed and expanded twice
- Evaluation report to Congress demonstrates extensive progress being made in key areas including
- Identifying genetic & environmental causes of type 1 diabetes
- Preventing or reverse type 1
- Developing cell replacement therapy
- Preventing or reduce hypoglycemia
- Preventing or reducing complications from diabetes
- Attracting new talent and apply new technologies
- Research helps those with type 1 and type 2 diabetes as well as autoimmune diseases such as lupus and rheumatoid arthritis

## 	Without a Renewal, a 35% Cut

**	****Without a Renewal, a 35% Cut**

## How You Can Help

- Encourage your Representatives and Senators to co-sponsor legislation to renew the Special Diabetes Program (H.R. 2762 and S. 1494) and get it enacted this year
- Sign up to be a JDRF advocate and encourage your friends and family to do so at www.jdrf.org/advocacy
- Thank elected officials who support our cause
- Get involved in your local JDRF chapter to help JDRF fund research for a cure