# Presentation: 331834

## Semantic Medline:Multi-Document Summarizationand Visualization

- Thomas C. Rindflesch, Ph.D.Marcelo Fiszman, M.D., Ph.D. Halil Kilicoglu, M.S.

## Information management application

- Manipulate information in addition to documents
- Manage the results of PubMed searches
- Help users decide what to read
- Connect knowledge from various sources
- Integrate application interfaces

## Managing retrieval results

- breast cancer

**Notes:**
Manage the results of PubMed searches
Manipulate information in addition to documents
Help users decide what to read

## Managing retrieval results

- breast cancer

## Seamless integration of technologies

- Information retrieval
- PubMed - MEDLINE
- Natural language processing: SemRep
- Represent content of text with semantic predications
- Abstraction summarization
- Informative: Overview of most salient information
- Visualization
- Indicative: Links to source text and additional information

## Semantic Medline  Overview

- StructuredBiomedicalData

- UMLS

**Semantic****Predications**

- SemRep

**Informative****Graph**

- Visualize

**Salient****Semantic****Predications**

- Summarize

- Semantic Medline  Overview

**Text**

- MEDLINEClinicalTrials.gov

- PubMed

- Query

## Document selection

- UMLS

**Semantic****Predications**

- SemRep

**Informative****Graph**

- Visualize

**Salient****Semantic****Predications**

- Summarize

## MEDLINE citations

- UMLS

**Semantic****Predications**

- SemRep

**Informative****Graph**

- Visualize

**Salient****Semantic****Predications**

- Summarize

- MEDLINEClinicalTrials.gov

- PubMed

- Query

**Text**

## Semantic intepretation

**Informative****Graph**

- Visualize

**Salient****Semantic****Predications**

- Summarize

- MEDLINEClinicalTrials.gov

- PubMed

- Query

## Semantic interpretation

- ... aromatase inhibitor provides mortality benefit in early breast carcinoma ...

- ... determined the spectrum and frequency of ATM missense variants in 443 breast cancer patients ...

## Semantic predications

- UMLS

- SemRep

**Informative****Graph**

- Visualize

**Salient****Semantic****Predications**

- Summarize

**Text**

- MEDLINEClinicalTrials.gov

- PubMed

- Query

**Semantic****Predications**

## Summarization

- UMLS

- SemRep

**Informative****Graph**

- Visualize

**Text**

- MEDLINEClinicalTrials.gov

- PubMed

- Query

## Abstraction summarization

- Specify a topic
- Retain predications on the topic
- Eliminate uninformative predications
- Retain most frequent predications

## Salient semantic predications

- UMLS

- SemRep

**Informative****Graph**

- Visualize

- Summarize

**Text**

- MEDLINEClinicalTrials.gov

- PubMed

- Query

**Semantic****Predications**

**Salient****Semantic****Predications**

## Visualization

- UMLS

- SemRep

- Summarize

**Text**

- MEDLINEClinicalTrials.gov

- PubMed

- Query

**Semantic****Predications**

## Informative graph

- SemRep

- Summarize

- MEDLINEClinicalTrials.gov

- PubMed

- Query

**Semantic****Predications**

- Visualize

**Salient****Semantic****Predications**

## Semantic Medline  Live

## Home page

## Search MEDLINE

## Summarization options

## Summarization results

## More detail

## Substance interactions

## Acknowledgments

- Caroline Ahlers
- Marcelo Fiszman
- Philip Goetz
- Halil Kilicoglu
- Anna Ripple
- Graciela Rosemblat