BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 224074

## Energy Scale, offset(CC) determination

- I fixed a bug in my code, now the log likelihood plots look ok. For a set of 100k Z/γ*->ee pythia events, I did my toy MC smearing (parameters are copied from wz_epmcs for now) and varied scale and offset to compare with full MC to find the best values.
- What the toy smearing MC does: smear energy, eta and phi position.
- What the toy MC does not do:  no phi module shift correction, no EMID, preselection, trigger efficiency, trackmatching efficiency applied.

## Energy scale and offset (CC)

## Energy scale and offset(EC)

## Energy resolution constant term(CC)

- To determine constant term, I set other parameters to be the best ones. I used Z width method.

## Energy resolution constant term(EC)

## Comparison between Full MC and Toy smearing MC

- Discrepancy around 80 GeV, explain later

## Comparison between Full MC and Toy smearing MC

##  The discrepancy around 80 GeV for invariant mass between full MC and toy MC?

- When I exclude H matrix cut for full MC, and remove fiducial requirements,

## Z_pT(gen) Vs. Z_pT(smear)

- To see how much the smearing works:

- So 2 GeV binning is ok?

## Z_pT(gen) Vs. Z_pT(smear)

- 2 GeV binning up to 30 GeV

## Migration matrix

- To see the effect of detector smearing, I also measured the migration matrix by looking at my toy smearing program (which is tuned as according to Zee full MC ). Basically, I just look at each generator event(if 2 electrons with pt>25) and compute ZpT, then smear it and see which bin will the smeared ZpT goes in. So, finally, M(i)(j)=s(i)(j)/g(i). Where g(i) is the number of generator events in bin i, s(i)(j) is the number of events in bin j of smeared ZpT distribution coming from bin i of generator ZpT distribution.
- Next slide will show the migration matrix for 100k Z/γ*->ee events. To see the effect of smearing, I have not applied Z selection cuts yet. So basically every smeared event is considered a Z event and the normalization on each row is 1. The binning is: 2GeV/bin ,0-18 GeV

## Migration matrix

| bin | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1 | 0.66 | 0.33 | 0.028 | 0.0046 | 0.0046 | 0.0017 | 0.0032 | 0.0035 | 0.0022 |
| 2 | 0.13 | 0.66 | 0.2 | 0.012 | 0.0009 |  |  |  |  |
| 3 | 0.0053 | 0.15 | 0.65 | 0.19 | 0.01 | 0.0005 |  |  |  |
| 4 |  | 0.0077 | 0.16 | 0.63 | 0.19 | 0.012 | 0.0004 |  |  |
| 5 |  | 0.0004 | 0.0063 | 0.16 | 0.64 | 0.18 | 0.012 | 0.0005 |  |
| 6 |  | 0.0002 | 0.0007 | 0.005 | 0.16 | 0.62 | 0.2 | 0.0097 | 0.0002 |
| 7 |  |  |  |  | 0.0093 | 0.15 | 0.62 | 0.21 | 0.014 |
| 8 |  |  |  |  | 0.0004 | 0.0048 | 0.16 | 0.63 | 0.2 |
| 9 |  |  |  |  |  |  |  | 0.16 | 0.62 |

- Diagonal number is too low?should we increase bin width?
# Presentation: 009847

## Muon Trigger WBS Outline

- Electronics
- (update) specification: write/review/milestone
- preliminary design, behavioral simulation
- design capture, verification via simulation
- procure parts
- perform layout, emc analysis, fabricate
- assemble first, test first
- assemble balance, test balance
- (update) final specification, documentation
- review, rework as required, milestone (each board project)
- final review, rework as required, milestone (muon trigger)
- Packaging, Powering, Monitoring, Cooling and Protection
- Alarms and Limits Interface (to the C/M&T)
- Hardware and Software Specific To Muon Trigger Development and Testing
- Software
- Muon Trigger Integration and Testing
- ES&H
- Transportation to and Installation and Testing at C0
- Muon Trigger Task Management
# Presentation: 202492

## Refrigerant Choice In the Obama Administration:What Risks, What Benefits?

- Presentation
**Mobile AC Climate Protection Partnership Meeting **
- Frederick R. Anderson
- December 9, 2008

## Now Not LaterAffordable Climate Protection

- Unique opportunity right now to demonstrate climate commitment
- Regulation more likely when deadlock occurs – a lose-lose situation
- Look instead for prompt win-win-plus consensus
- Seek global leverage & harmony through a stakeholder-endorsed voluntary plan
- MAC community leadership is the solution

## Common Sense Global Choice:HFC-1234yf for Mobile AC

- Huge climate and energy efficiency benefits vastly outweigh costs
- Fuel savings pay for the low system cost
- Global equity: affordable in developed & developing markets
- Reliability will satisfy the most demanding car owners
- Much faster global transition than to CO2
- Safe and reliable repair by independent technicians

## CO2 Risk in Developing Countries

- Acute toxicity & high pressure risks from improper repair and fabricated tools and parts
- Poor energy efficiency and cooling in small cars undermine climate protection & cooling performance
- Insurmountable training & equipment requirements for safe repair in all but OEM dealers & elite shops
- Risks & benefits: comparison of fuel cost, toxicity, and safety strongly favors HFC-1234yf

## Challenges

- Accommodate German CO2 choice
- Communicate HFC-1234yf’s environmental superiority
- Rebut false flammability claims
- Remove final barriers in all markets
- Cooperate on successful HFC-1234yf introduction

## Getting out the Facts: Time for R-1234.com?

- Transparently report HFC-1234yf’s advantages
- Encourage cooperation and partnerships
- Provide technical reports for download
- Prompt response to misleading information
- Communicate with influential policy makers
# Presentation: 423180

## CASE Comprehensive Cancer CenterBob LaneseProgrammer / Analyst Clinical Trials Unitrobert.m.lanese@case.edu

- caBIG

- Clinical Trials Management Workspace
- Adopter

## Data Provided

- CASE Comprehensive Cancer Center

-  Demographic, Clinical, Laboratory, and Radiology data covering over 5000 patients and 450 protocols
-  Phases 1,1/2, 2, 3
-  Therapeutic and Non-therapeutic studies

## Envisioned Tools

- CASE Comprehensive Cancer Center

-  CDUS and Theradex electronic reporting
-  SAE electronic reporting
-  Elimination of double data entry by using a one-pass process from the initial data

## Evaluation of Tools

- CASE Comprehensive Cancer Center

- Clinical and data adopter teams
-  Clinical Process: clinical trials administrator, clinical trials research nurses
-  Data Process: database administration, data managers
-  Processes will overlap through feedback loops

## System Integration

- CASE Comprehensive Cancer Center

-  Adopted on a development environment proceeding to production environment
-  Hardware based on Intel chipset
-  OS based on Microsoft, (Windows 2000)

## End User Testing

- CASE Comprehensive Cancer Center

-  Interaction between Programmers, Data Manager, and Clinical Trials Administrator based on:
-  Application testing
-  Data validation testing

## Software Validation

- CASE Comprehensive Cancer Center

-  Define a precise scope with a set of functional requirements before development
-  Develop rule-based testing methodologies based on industrial testing standards as well as specific application testing standards

## Interaction

- CASE Comprehensive Cancer Center

-  Designation of a team from both development and adoption sides and development of  appropriate workflow processes
-  Web-based project workspace linked to developers and adopters to disseminate information.
-  Web-based discussion forum
-  Conference calls, meetings, technical support
-  Traditional methods
# Presentation: 298523

## Welcome!NASA / DHS UAV Capabilities Assessment Workshop

- July 6 & 7, 2005
- Herndon, VA

- Note:  This workshop is an open forum, no ITAR restrictions

## Workshop Structure

**DHS/NASA High**
**Level Briefings**

**Future**
**Mission**
**Analysis**

**Areas of **
**Collaboration?**

**Future UAV**
**Technology Brief**

- today

- 2015

- Civil UAV
- Capability
- Assessment

## Civil UAV Capabilities Assessment

- Task: Develop a Civil UAV Capability Assessment (2015 Time Frame)
- Customers: Sub-Orbital Science Program, Vehicle Systems Program
- Complement DOD roadmap
- Homeland Security, Commercial, Land and Coastal Regions Management, Earth Science focus areas
- Objectives:
- Influence the management of the UAV technology portfolio based on user defined future needs and missions
- Broad civil arena assessment vetted with participating agencies: NASA, NOAA, DOE, U. S. Forest Service, etc.
- Initial draft version is available via web-site: _[http://](http://www.nasa.gov/centers/dryden/research/civuav/index.html)__[www.nasa.gov/centers/dryden/research/civuav/index.html](http://www.nasa.gov/centers/dryden/research/civuav/index.html)_
- Information sources for initial version: 35 missions
- primarily Earth science missions (SSMF, GSFC Earth Science Missions, NASA/DOE/NOAA workshops and UAV Initiative Advocacy)
- 21 basic technologies and capabilities identified to support missions
# Presentation: 739556

## NCSLI PerspectiveConformity Assessment WorkshopDecember 3, 2001

- Georgia L. Harris
- NCSLI V.P. Publications
- (NIST, Office of Weights & Measures)

## NCSLI Involvement

- WHY?
- Primary focus: Laboratory Accreditation
- Policy on Laboratory Accreditation, Registration, and Certification
- Standards Writing & Adoption & Resources
- Participation with NACLA, ILAC, NMIs  (incl. NIST)
- Collaboration
- Secondary focus: Certification for product evaluation (barriers to trade)

## Policy

- NCSLI International Position Statement published April 2001 NCSLI Newsletter
- clarifies terminology related to Laboratory Accreditation, Registration, Certification, and Third Party
- focus on accreditation and *competence*

## Standards Writing and Adoption & Resources

- ANSI/NCSLI Z 540, Standards Writing Committee
- U.S. National Standards:
- Publications & Training

## Participation

- Representation on NACLA Board
- Sponsorship of NACLA (Patron Member)
- Stakeholder member in ILAC
- Annual meetings with NMI management (NIST, CENAM, NRC)

## Collaboration

- Requested NIST establish a laboratory accreditation program for “calibration laboratories” in NVLAP
- Includes government representatives on writing committees to encourage adoption of standards when published:
- Adoption of Z 540-1-1994 in NVLAP & OWM laboratory criteria at NIST
- Adoption of Z 540-1-1994 by DOD, DOE, etc for calibration laboratories
- E.g., DOE adoption of ISO/IEC 17025
- FAA contacted Airline Industry Committee - regarding Z 540-1 appplicability to FAA regulations

## Collaboration

- Met with Jim Turner, House Majority Counsel to Committee on Science, Commerce, Technology July 27, 2001
- laboratory accreditation issues; lack of uniformity in acceptance of accreditation by Federal agencies, effectiveness of NCSLI in representing interests of members
- possible proposal to OMB

## Suggestions

- Government agencies should recognize competence of laboratories accredited to international quality standards
- versus additional audits and requirements
- compare ISO/IEC 17025 and NRC 10 CFR 50, find out if there are gaps, then address the gaps by 17025 updates
- environmental, chemical, biological
- Collaboration among Federal & accredited labs to provide traceable calibration services
# Presentation: 438310

## A Chemical and Vegetative Characterization of the Ichetucknee River

- Sky K. Notestein and Thomas K. Frazer

## Sampling methods

- Surveyed April 2003 & 2004
- 31 Transects with 5 stations each
- Suite of parameters measured
- Depth, Flow, Terrestrial Cover, Substrate Type, Dissolved Oxygen, Conductivity, pH, Kd
- Coverage and Biomass of SAV
- Periphyton abundance on SAV
- Also in 2004
- Six Feeder Springs Sampled
- Water column TN, NH4+, NO3-, TP, SRP, color and chlorophyll measured

## Water Chemistry Results

- Elevated nitrate concentrations with a decline downstream
- Average Ichetucknee River Values (n=30)
- TN: 625,    NO3-: 523,    NH4+: 11,    TP: 47,    SRP: 43 μg/L

## Water Chemistry Results

- Among Spring Comparisons

## SAV Results

- Species observed similar to Dutoit (1979), Canfield & Hoyer (1988) studies
- High Biomass: 4.9 kg wet wt./m2 (2 year average)
- High Coverage: 78 percent (2 year average)

-  Correlations between SAV abundance:
- Negative for Terrestrial Cover
- Substrate type important
-  Positive for Depth
-  Positive for Flow

## Periphyton

- Periphyton abundance moderate in river
- Negatively correlated with flow rate and depth
- Periphyton abundance variable in feeder springs
- Positively correlated with phosphorus concentrations within feeder springs

- r2= 0.25, p = 0.04

- Feeder Springs 

## SAV comparison to other systems

- Ichetucknee River

- Chassahowitzka River

- SAV: 4.9 kg wet wt/m2
- Nitrate: 523 μg/L
- SRP: 43 μg/L
- Depth: 1.5 m
- Flow: 0.21 m/s

- SAV: 1.3 kg wet wt/m2
- Nitrate: 436 μg/L
- SRP: 15 μg/L
- Depth: 1.1 m
- Flow: 0.09 m/s

## Stream Flow and SAV

- Haze is calcium carbonate precipitate
- CO2 likely limiting SAV
- Periphyton and macroalgae better competitors for gas/nutrients (surface area to volume ratio)

- Chassahowitzka River at minimal flow rate

## Conclusions

- Premier spring-fed river
- SAV species composition appears to be stable, exotic species absent
- Biomass and cover are high relative to many other spring-fed systems
- Minimal amount of macroalgae present
- Water column nutrient concentrations
- Elevated relative to historic concentrations
- Are not likely limiting, however, phosphorus and periphyton abundance correlated in feeder springs
- High stream flow beneficial to SAV?
- Empirical relations suggest that reductions in flow or depth may reduce SAV coverage and biomass
- High stream flow moderating nutrient impacts by:
- increasing periphyton/macroalgae sloughing?
- increasing CO2 diffusion rates for SAV?
# Presentation: 099252

## J. Lahann Lab

**J. Lahann Lab**

- http://www.engin.umich.edu/dept/che/research/lahann/

**Grant No.: DMR-0449462**
**Program Director: Andrew J. Lovinger**

**CAREER: An Integrated Research and Education Plan for the Advancement of Surface Engineering via Thin Polymer Films**** **

**Controlled protein adsorption by digital micromirror-modulated UV projection for on-stent patterning.**

**Patterned click reaction using alkyne-functionalized *****reactive coatings.*****6**

**Controlled immobilization using multi-potent *****reactive coatings *****via CVD copolymerization.****5**

**Chemical vapor deposition polymerization within confined geometries.****3**

- H.Y. Chen, J. Lahann, Fabrication of Discontinuous Surface Patterns within Microfluidic Channels Using Photodefinable Vapor-based Polymer Coatings. *Analytical Chemistry* **2005**, *77*(21), 6909-6914.
- H. Nandivada, H. Y Chen, J. Lahann. Vapor-Based Synthesis of Poly[(4-formyl-p-xylylene)-co-(p-xylylene)] and Its Use for Biomimetic Surface Modifications. *Macromolecular Rapid Communications* **2005**, 26, 1794-1799.
- H.-Y. Chen, Y. Elkasabi, J. Lahann, Surface Modification of Confined Microgeometries via Vapor-Deposited Polymer Coatings. *Journal of the American Chemical* *Society* **2006**, *128*(1), 374-380.
- J.M. Wu, Y. Chung, K.J. Belford, G.D. Smith, S. Takayama, J. Lahann, A Surface-Modified Sperm Sorting Device with Long-Term Stability. *Biomedical Microdevices* **2006 **8, 99-107.
-  Y. Elkasabi, H.-Y. Chen, J. Lahann, Multi-Potent Polymer Coatings Based On Chemical Vapor Deposition Co-Polymerization. *Advanced Materials* **2006**,18, 1521-1526 (highlighted as cover article).
- H. Nandivada, H.-Y. Chen and J. Lahann, Reactive polymer coatings that “click”, *Angewandte Chemie International Edition*, **2006**,45, 20, 3360-3363.
- J. Lahann, Vapor-Based Polyreactions With Use For Biomedical Applications. *Polymer International,* **2006** (invited review, accepted for publication).
- M. Yoshida, R. Langer, A. Lendlein, and J. Lahann, From advanced biomedical coatings to intelligent biomaterials, *Polymer Reviews* **2006 **(invited review, guest editor: Marek Urban, accepted for publication).

**Publications:**

## J. Lahann Lab

- http://www.engin.umich.edu/dept/che/research/lahann/

**Grant No.: DMR-0449462**
**Program Director: Andrew J. Lovinger**

**CAREER: An Integrated Research and Education Plan for the Advancement of Surface Engineering via Thin Polymer Films**** **

**Patterned protein surface made by High-school student Radicia Laing during her summer research project in the Lahann Lab. As a demonstration, Radicia (with help of graduate student Hsien-Yeh Chen) wrote a text with proteins onto a surface.**

**Undergraduate Student Sandy Yu and graduate student Hsien-Yeh Chen working on a vapor-based polymer synthesis. **

**J. Lahann Lab**
# Presentation: 684710

## August 2, 2006

- Advisory Committee

- MTAC

**August 2, 2006**

**Robert J. Pedersen**
**Chief Financial Officer &**
**Executive Vice President (A)**

## Financial PerformanceMay Year-To-Date, FY 2006

## Income Statement – May Year-To-Date

**($ Millions)**

**$1,837  **

**Numbers may not add due to rounding.**

**[  ] = Unfavorable variance to plan.**

## Volume and Revenue – Change to SPLY– May YTD

**Volume and Revenue – Change to SPLY– May YTD**

## Total Revenue – May Year-To-Date

**Total Revenue = $49.2B**

## Total Commercial Revenue – May YTD

**$148.1M Under Plan, -0.4%**

## Total Retail Revenue – May Year-To-Date

**$519.8M Over Plan, +4.4%**

## Other Retail Channels Revenue – May YTD

**($ Millions)**

## Expense Increase over FY 2005 – May YTD

**($ Millions)**

**Consumer Price Index (CPI-U)                       4.2%                  **

## Total Factor Productivity – May YTD

** ****Total Factor Productivity       0.4%       0.9%       **

** ****Output Per Workhour             1.4%       1.3%      **

_**Actual**_

_**FY Plan**_

## CPI vs. CPI Excluding Energy

**(% SPLY)**

**CPI vs. CPI Excluding Energy**

## Rate Case Perspective

## Food For Thought

**Historically low 1% contingency**
**Record low recovery of prior years’ losses**
**Ambitious cost reductions [$1 billion per year]**
**High ROI from investments**
**Very low inflation and expense growth**
**Solid economic growth**

## Going Forward

**Revenue above plan – keep it growing**
**Expenses above plan – hold the line**
**Review assumptions, risks, and forecasts**
**Development of Integrated Financial Plan for 2007**

## August 2, 2006

- Advisory Committee

- MTAC

**August 2, 2006**

**Robert J. Pedersen**
**Chief Financial Officer &**
**Executive Vice President (A)**
# Presentation: 467235

## HHS Memo On FISMA and Grants

**Secure One HHS**
**Memorandum**
- From: Jaren Doherty - Chief Information Security Officer
- Sent: October 29, 2007
- To: Operatng Division (OPDIV) Chief Information Officers (CIO)
- Subject: Applicability of the Federal Information Security Management Act (FISMA) to Department of Health and Human Services (HHS) Grantees
- The Federal Information Security Management Act (FISMA) of 2002 (44 U.S.C. 3541 et seq.) was implemented in order to improve the security of federal information systems and federal information. While FISMA does not address applicability to grantees, annual FISMA reporting guidance released by the Office of Management and Budget (OMB) includes references to grantees and their responsibilities to protect the Federal Government's information. According to the most recent FISMA guidance, OMB Memorandum M-07-19, *FY 2007 Reporting Instructions for the Federal Information Security Management Act and Agency Privacy Management - *
*FISMA's requirements follow agency information into any system which uses it or processes it on behalf of the agency. That is, when the ultimate responsibility and accountability for control of the information continues to reside with the agency, FISMA applies.*
- As such, FISMA applies to grantees only when they collect, store, process, transmit or use information on behalf of HHS or any of its component organizations.1
- In all other cases, FISMA is not applicable to recipients of grants, including cooperative agreements with grantees. The grantee retains the original data and intellectual property, and is responsible for the security of this data, subject to all applicable laws protecting security, privacy and research. If and when information collected by a grantee is provided to HHS, responsibility for the protection of the HHS copy of the information is transferred to HHS and it becomes the agency's responsibility to protect that information and any derivative copies as required by FISMA.
- 1 The term "on behalf of" indicates that only those entities that are acting, under agency principles, as agents, where HHS (or a component) is the principal, are covered by FISMA. While the legislative history and reports connected to FISMA provide little guidance on the meaning of "on behalf of," the House Report on one of FISMA's predecessors, the Computer Security Act of 1987, H.R. Rep. 100-153, pt. 1, states that "on behalf of" means that the entity is acting as a "direct extension of the federal government" and "to accomplish a federal government function". This point must be appropriately communicated, especially to study participants. For example, if a patient participates in a medical study, identification of the study as an HHS project (whether it is the case or not) could establish and expectation that the information is being gathered by or on behalf of HHS and will be adequately protected by HHS. Conversely, a study which identifies the grantee as the conductor of the study would not establish such an expectation.
# Presentation: 218546

## The Genetic Testing Quality Assurance Program

**Michele Caggana, Sc.D., FACMG**
**Emory University/Centers for Disease Control and Prevention **
**Atlanta, GA**
**May 20, 2004**

## MY  ROLE  AS  SECTION  HEAD 

**Approve Certificate of Qualification**
**Review and Critique Method Validation**
**Review Non-Permitted Lab Requests**
**Review Survey Results**
**Compile Questionnaire Data**
**Liaison for Counselors, Testing, Coverage**
**Field**** ****Questions About CLEP or the Section**
**Insurance Companies**

***Wadsworth Center***

## INITIAL  LABORATORY  PERMIT APPLICATION  (GETE)

_**	**__**Requirements**_
**Application Form with Categories**
**Application Fees $1,100 **
**SOPM Validation**
**Certificate of Qualification Holder/Dir. or Asst.**
**Survey and Correction of Deficiencies**
**Issuance of Permit**
***http://www.wadsworth.org/labcert/***

***Wadsworth Center***

##  CERTIFICATE  OF  QUALIFICATION

**  **_**Requirements**_
**Earned Doctoral or Medical Degree **
**Four Years Post-doctoral Training; 2 in GETE**
**Knowledge of the Diseases and Methods**
**Knowledge of Linkage and Bayesian Analyses**
**Experience or Training in Clinical Laboratory       Management  **
***May be Restricted to Commensurate Experience***

***Wadsworth Center***

## IMPORTANT  !!!!

**In Genetic Testing:**
**Approvals To Offer Tests Are **
**ANALYTE-SPECIFIC**

***Wadsworth Center***

***This means that the laboratory has specific ***
***approval for each test they perform.***

## WHAT  IF  NO  LAB  IS APPROVED?

**Non-Permitted Lab Request Form**
**Test, Patient, Referral Information**
**Justification for Testing**
**Urgency**

***Wadsworth Center***

***CLEP generates admin letter to the ***
***requestor, referral lab, and referring lab***

## WHAT  REQUESTS ARE  APPROVED?

**Continuity of Care**
**Additional Testing After Approved Lab Has**
**Completed Testing**
**Compassion**

***Wadsworth Center***

***Approvals are not issued for financial reasons***

## LIMITATIONS

**Referral Laboratory CLIA-approved**
**	****	****Non-US -- limited**
**“****Restricted Laboratory Permit”**
**Up To Fifty Tests Annually For A Given Analyte**

***“******The patient, physician, and laboratory must ***
***acknowledge that these tests are conducted ***
***outside the regulatory oversight of the Clinical***
***Laboratory Evaluation Program and its quality***
***assurance surveillance.”***

***Wadsworth Center***

## SOME NUMBERS TO PONDER

**60+ Laboratories with Genetic Testing Category**
**224 Approved Certificate of Qualification Holders**
**130 Molecular Tests**
**50+ Biochemical Tests**
**620+ SOPM Reviews**
**1326 Non-Permitted Laboratory Request Reviews****  **

***Wadsworth Center***
# Presentation: 923883

## NASA Launch Services Manifest

** ****WISE (D3) **

**   ****11/1/09**

** **

** ****TBD (DH)  **

** ****10/15/08 **

**GOES-O (DIV)**

**     ****4/2008**

**GOES-P (DIV)**

**   ****4/2009**

**LRO/LCROSS (AV)   **

**        ****10/28/08**

**MARS SCIENCE**

**     ****LAB  (AV)**

**   ****NET 9/15/09**

** ****Juno (AV)**

** ****8/11/2011  **

**LDCM  (AV) **

**7/2011 **

**JWST (Ariane)**

**       ****6/2013**

**    ****SDO (AV) **

** ****12/01/08 (UR)  **

**SpaceX-1  **

**3-Qtr/2008**

** ****SpaceX-2**

**  ****2-Qtr/2009**

**  ****SpaceX-3 **

**  ****3-Qtr/2009**

**Discovery 11**

**      ****9/2011 **

** ****RBSP **

**   ****3/2012 **

**SMEX-13**

**  ****4/2013**

**SMEX-14**

**  ****4/2014**

**SMEX-12**

**  ****4/2012**

**TDRS-L  **

** ****9/2013 **

**GPMC**

**  ****6/2014**

**Discovery - 12  **

**      ****11/2012 **

**MARS SCOUT 2 **

**        ****12/2013 **

**   ****MMS **

**10/2014  **

** ****TDRS-K  **

** ****12/2012 **

**GOES-R**

** ****CY 2014**

**K**

**V**

**V**

**V**

**V**

**V**

**V**

**V**

**V**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**A**

**V**

**F**

**A**

**A**

**NOTE: COTS Demo launch dates shown**

**for informational purposes only - LSP**

**does not control these dates.**
# Presentation: 676650

## Time to Disease ProgressionStudy M00-211 – ITT

**Time to Disease Progression****Study M00-211 – ITT**

| P (G1,1) = .136 |
| --- |
| HR = 0.885 (95% CI = 0.755 – 1.037) |

**Scheduled radiographic scans**

## Time to Disease Progression Study M00-211 – Patients with Bone Metastases

| P = .016 |
| --- |
| HR = 0.813 (95% CI = 0.685 – 0.965) |

## Time to Disease Progression:O’Brien-Fleming AdjustmentStudy M00-211—Patients with Bone Metastases

| P = .023 |
| --- |
| HR = 0.818 (95% CI = 0.691 – 0.968) |

## Summary of Endpoints

|  | ITT |  |  |
| --- | --- | --- | --- |
| Time to disease progression

 | HR = 0.885 
(0.755, 1.037) 
P = .123 |  |  |
|  |  |  |  |
|  |  |  |  |

## Summary of Endpoints

|  | ITT |  |  |
| --- | --- | --- | --- |
| Time to disease progression

 | HR = 0.885 
(0.755, 1.037) 
P = .123 |  |  |
| BAP | P = .001 |  |  |
| PSA | P = .023 |  |  |
|  |  |  |  |
|  |  |  |  |

## Summary of Endpoints

|  | ITT |  |  |
| --- | --- | --- | --- |
| Time to disease progression

 | HR = 0.885 
(0.755, 1.037) 
P = .123 |  |  |
| BAP | P = .001 |  |  |
| PSA | P = .023 |  |  |
| Prostate Cancer Subscore | P = .032 |  |  |
| PCS pain | P = .015 |  |  |

## Summary of Endpoints

|  | ITT | Bone metastases(Unadjusted) |  |
| --- | --- | --- | --- |
| Time to disease progression

 | HR = 0.885 
(0.755, 1.037) 
P = .123 | HR = 0.813 (0.685, 0.965) 
P = .021 |  |
| BAP | P = .001 | P < .001 |  |
| PSA | P = .023 | P = .015 |  |
| Prostate Cancer Subscore | P = .032 | P = .035 |  |
| PCS pain | P = .015 |  |  |

## Summary of Endpoints

|  | ITT | Bone metastases(Unadjusted) | Bone metastases(O’Brien-Fleming) |
| --- | --- | --- | --- |
| Time to disease progression

 | HR = 0.885 
(0.755, 1.037) 
P = .123 | HR = 0.813 (0.685, 0.965) 
P = .021 | HR = 0.818(0.691, 0.968)
P = .023 |
| BAP | P = .001 | P < .001 |  |
| PSA | P = .023 | P = .015 |  |
| Prostate Cancer Subscore | P = .032 | P = .035 |  |
| PCS pain | P = .015 |  |  |

## Course of StudyStudy M00-211

**Powered to detect a treatment difference at 650 events **
**June 2001 – Study initiated **
**Sept. 2002 – IDMC halts enrollment at 809 patients**
**Jan. 2003 – IDMC recommends study stop (343 events)**
**Feb. 2003 – Sites notified of study closure**
**Mar. 2003 – Last patient’s final visit (610 events)**
**May 2003 – Study blind broken **
**Study blind maintained through collection of events**

## Time to Disease Progression Study M96-594 – ITT

| 10 mg vs. placebo |
| --- |
| P = .132 |
| HR = 0.769 (95% CI = 0.545, 1.085) |

## Group Sequential Stopping Rule

**One-sided symmetric ****(Emerson and Fleming, 1989)**
**Type I error 0.025, power 90%**
**“****Conservative early” boundaries**
**Efficacy: reject null hypothesis**
**Futility: reject alternative of effect similar ****to M96-594**
**G****1,1**** statistic**

## Time to Radiographic ProgressionStudy M00-211 – Patients With Bone Metastases

**Time to Radiographic Progression****Study M00-211 –**** ****Patients With Bone Metastases**

| P = .080 |
| --- |
| HR = 0.846 (95% CI = 0.698 – 1.025) |

**Events = 212/355 (59.7%)**
**Events = 206/335 (61.5%)**
# Presentation: 838160

## Institute for Federal Printing and Electronic PublishingU.S. Government Printing OfficeStop FP – Room C565732 North Capitol Street NWWashington, DC  20401202-512-1283ifpep-registrar@gpo.govHURRY - Enroll Now !The Institute only has a few more registrations available for the following class: “Proof and Press Sheet Inspections”   $200   October 22, 2007

## Institute for Federal Printing and Electronic Publishing

- U.S. Government Printing OfficeStop FP – Room C565732 North Capitol Street NWWashington, DC  20401202-512-1283**ifpep-registrar@gpo.gov****HURRY - Enroll Now !**
**The Institute only has a few more seats available for the following upcoming class:**
**“****Proof Getting the Best From Desktop Publishing”        **
**                  ****September 11-12, 2007        $420**
**“****Checking Desktop Publishing Files – Preflighting”**
**                      ****September 13, 2007****	****$300**
**“****Digital, On-Demand and Variable-Data Color Printing”**
**                   ****September 19-20, 2007      $400**
_**Note**_**:  For every two students enrolled, the third student can attend  for  half-price. **
# Presentation: 732140

## Richieste Addizionali Missioni Estere 2005

| Pisa | 94 KE |
| --- | --- |
| Udine | 5 KE |

## UDINE

- Diego Cauz  1 viaggio (manutenzione):  3 KE                           Mario Paolo Giordani: 2 viaggi(turni, analisi e Dilep. Trig.): 6 KE
- Giovanni Pauletta : 1 viaggio (manutenzione ed analisi): 3 KE
- Melisa Rossi: 1 mese - uomo  (analisi)  : 6 KE
- Totale  18 KE                                                                   Disponibilita:   13 KE                                                           Richiesta fondi aggiuntivi 5 KE

## PISA

| Bellettini | 2 mu |
| --- | --- |
| Ristori | 3 mu |
| Annovi (SVT) | 2 mu |
| Torre (SVT) | 1 mu |
| Ulteriori Interventi SVT Upgrade | 1 mu |
| Metabolismo residuo:
(35 FTE )x (3/12 anno)x 1.5 mu | 13 mu |
| TOTALE | 22 mu |
| RICHIESTI | 14 mu |

## Consuntivo Missioni Estero 2005

- Bologna       108         75        33    Frascati      107         76        31    Padova        120         98        22    Pavia          20         13         7    Pisa          509        487        22    Roma          220        130        90    Trento         40         39         1    Trieste        54         37        17    Udine          54         41        13
- Totale       1232        996       236

- Situazione al 1 Settembre 2005
# Presentation: 670499

## Mean Value = 0.85, Weighted Mean = 0.85

## Mean Value = 0.84, Weighted Mean = 0.85

## Mean Value = 0.88, Weighted Mean = 0.88

## Mean Value = 0.86, Weighted Mean = 0.86

## Mean Value = 0.86, Weighted Mean = 0.86

## Mean Value = 0.86, Weighted Mean = 0.85

## Mean Value = 0.91, Weighted Mean = 0.91

## Mean Value = 0.90, Weighted Mean = 0.90

## Mean Value = 0.91, Weighted Mean = 0.91

## Mean Value = 0.91, Weighted Mean = 0.91

## Mean Value = 0.87, Weighted Mean 0.87 

- Mean Value = 0.87, Weighted Mean 0.87

## Mean Value = 0.91, Weighted Mean = 0.90

## Mean Value = 0.91, Weighted Mean = 0.91

## Mean Value = 0.88, Weighted Mean = 0.88
# Presentation: 770768

## LASER SEARCH AND RESCUESenSytech, Inc.Ann Arbor, MI

**INNOVATION**
- Developed system that shortens rescue time, enhances the survival rate and reduces the cost of conducting a search and rescue mission.

**S****mall**
**B****usiness**
**I****nnovation **
**R****esearch**

**      **

**                        ****ACCOMPLISHMENTS**
- Created a new search and rescue instrument that uses passive retroreflecting material as a target marker and an ultrasensitive active airborne scanner with a modulated laser illuminator.
- Eye-safe system with a day/night search capability of 140 square-miles/hour, capable of detecting a one square-foot marker from an altitude of 4,000 feet, life preservers from 2,000 feet, and real-time data  processing for automatic target detection.
- GPS integrated with the L-SAR system establishes the ground position of each locator.
**            ****COMMERCIALIZATION**
- The  retroreflector material is commercially available and represents a whole new market for the suppliers of the material and to the manufacturers of marine and aircraft emergency gear.
- Potential worldwide market for this technology.

**   ****GOVERNMENT/SCIENCE APPLICATIONS**
- Pending NASA proposal to conduct a 1 year demonstration with the Civil Air Patrol in Alaska.

**Goddard Space Flight Center**

- 1994 Phase II, SS5-051, 2/16/01

***Laser Search and Rescue System (L-SAR)***

- Points of Contact:
- 	-  NASA -Jim Christo; 301-286-9015
- 	-  SenSytech, Inc. - Fred Osterwisch; 734-769-5649
# Presentation: 391199

## Data Taking Jan 26 – Feb 1

**Data Taking Jan 26 – Feb 1**

## First 4 Hours of Store 3214

## Beam Spot

**  ****0**

**–****0.1mm**

**  ****0.5mm**

**  ****0.9mm**

**Within specifications**
**(<1mm)**

## Beam Tilt

**  ****0**

**–****100********rad**

**Horizontal:**
**almost perfect**

**–****400********rad**

**–****200********rad**

**Vertical:**
**close to critical**
**specification:**
**<200********rad**

## Silicon Saga

- Beginning on Thursday around 6pm, we observed frequent (~ once per hour) ***trips of the Silicon power supplies on the ***_***East***_** **side (water drip detection)
- After several attempts to recover, the Silicon was left off, we requested an access, and continued to take data without half of the Silicon detectors
- Access started Friday 6:30 am. We expected one shift to complete the work (cathedral area)
- Experts quickly discovered that *trips were the result of a malfunction of the water drip detection system* (loose connections). Fix took about 5 hours – multiple layers of Silicon cables complicated the work. Bypassed the drip sensor, since water in that crate is not flowing following an earlier (real) water leak.
- Friday 2pm: Ready to start closing the detector, beginning to power up Silicon

## Silicon Saga cont.

- On power-up, ***failed on one of the power supplies on the ***_***West***_*** side***. Had no choice but to open up the West side as well
- After opening, discovered a **real water leak**. Found water accumulation in the power supply, rust, and apparently water had dripped on one of the interface boards located below the power supply, causing it to fail. Water leak was too small to trip the drip detectors
- The leak was quickly fixed, and it was attempted to dry the power supply in place. Gave up after 1.5 hours
- A **spare power supply was installed**, only to find that it was not holding as well. Suspicion that boards in the crate might be responsible, but couldn't find anything conclusive within the next 2 hours
- Friday 7pm... it's getting late – technicians have been around for more than 12 hours. Called MCR for search & secure, sending tech crew home
- Before S&S team arrived, swapped in another (not fully tested) spare power supply – this one worked!

## Slide 7

## Silicon Saga cont.

- Spent the next store (Saturday) collecting special runs for calorimeter. Detector in open configuration, magnets off
- Went in again Saturday 17:00 for 4 hours to close the power supply, install the replacement for the damaged interface board, adjust voltages, perform a system test, and finally close the detector
- _In summary_
- The originally scheduled work on the East side was performed efficiently and in time
- Another major problem (“luckily”?!?) uncovered itself during the access, and required an extension and a second access
- Thanks to the hard effort of Silicon experts, and the mechanical and electrical support teams, all problems were resolved as quickly as possible, and we came out of the access without any remaining damage

## Store 3212 (Sun/Mon)

## Slide 10
# Presentation: 517001

## Lithium Hydride Absorber Program

**A. Bross for**
**C. M. Lei**

## LiH Discs

**An instrumented LiH disc (30 cm diameter, 4 cm thick) for measuring thermal properties**
**Two small (1.25” diameter X 0.25” thick) samples for radiation stability tests**
**One or Two LiH discs (50 cm diameter, 6.5 cm thick) **
** ****For use in MICE Step III.1**

**LiH Discs**

## MICE Step III.1

## Y12 National Security Complex 

**After some reflection (and some input from Chemists from Argonne Lab), the vendor decided casting LiH was too dangerous (production of H****2**** gas)**
**Negotiating with Y12 to fabricate these discs.**
**We are also investigating if the UK equivalent (AWE, plc – Atomic Weapons Establishment) can help**
**Produced by Hot Isostatic Pressing (150 ****o****C, 30,000 psi)**
**Will use existing mold**
**Final parts will be**
**Tested for Chemical composition and purity**
**Radio-graphed to ensure no voids**
**Machined to size**
**Dimensional inspection**
**Coated with epoxy completely**

**Y12 National Security Complex**** **

## Instrumental Disc

**12 Blind holes for housing thermo-couples**

##   The Set Up of the Thermal Test

- Stainless steel base structure

- High temp glass ceramic

- High temp low k gasket

- 1” copper tube with heaters

- 12” dia steel ring

- Machined LiH disc

- Thermocouples X12

- Foam board & gasket

- Flexible cooling tube

## The Set Up Ready for the Thermal Test

## A Couple of Quick Checks

- Heat Sink Check:
- A coil of Parflex flexible thermoplastic polyethylene tubing,  (1⁄4”OD, 0.04” wall) was wrapped around the steel ring;
- Chiller temperature was set at -10C;
- Steel ring temperature was at -1C.
- Heat Source Check:
- 3 kapton flex heaters with R=157 ohms were glued to the inside of the copper sleeve evenly;
- +123C was achieved on sleeve surface at applied voltage of 30V

##    The Hardware Ready to take the Disc

## The MICE Energy Absorber

- The absorber is fastened by two M8 screws and nuts first.

- Carbon-fiber Clamp Shells

- LiH Disc (~ 10 kg)

##     Installation in MICE

**This absorber is lowered down through the slot of the ss spool piece**
# Presentation: 916360

## Analysis of Strategies for Reducing Multiple Emissions from Power Plants:  Sulfur Dioxide, Nitrogen Oxides, and Carbon Dioxide

**Scott Sitzer**
**Energy Information Administration**

## Modeling Tools

- National Energy Modeling System
- Comprehensive Model of the Energy/Economy/Environmental System
- Reference Case Based on *Annual Energy Outlook 2001*

## Key Assumptions

- Emission Cap and Trade System
- Competitive Electricity Pricing in the Wholesale Market
- Marginal Unit Sets the Price

## Key Assumptions (contd.)

- NOx and SO2 Emissions 75 % Below 1997 Levels by Either 2005 or 2008
- CO2 Emissions at 1990 Levels By Either 2005 or 2008
- CO2 Emissions at “Kyoto” Levels by 2008-2012

## Key Findings

- NOx and SO2 Cases Have Little Impact on Price, But Increase Industry Costs
- CO2 and Integrated Cases:
- 	-Have Greatest Impact on Price
- 	-Reduce Need for NOx/SO2 Retrofits
- Achieving Reductions by 2005 Will Pose Challenge to Electricity and Natural Gas Industries

## 1997 Emissions, Reference Case Projections for 2010 and 2020, and Target Caps for Electricity Generators

## Electricity Generation by Fuel, 1949-1998, and Projections for the Reference Case, 1999-2020

## Projected SO2 Allowance Prices, 2000,2010, and 2020

## Projected Carbon Fees, 1999-2020

## Projected Capacity Additions by Fuel andProjected Retirements in the Integrated1990-7% 2005 Case, 1999-2020

## Electricity Generation by Fuel, 1949-1998, and Projections for the Integrated 1990-7% 2005 Case, 1999-2020

## Projected Electricity Prices, 1999-2020

## Projected Average Annual Changes from Reference Case Power Plant Costs and Revenues in the SO2 and NOx 2005 Cap Cases, 2005-2020

## Projected Electricity Prices, 2000, 2010, and 2020

## Average Projected Changes in Annual Household Electricity Bills Relative to Reference CaseProjections, 2005-2020

## Projected Natural Gas Consumption for Electricity Generation, 1999-2020

## Projected Domestic Wellhead Natural Gas Prices, 1999-2020

## Projected Renewable Electricity Generation by Fuel in the Reference and CO2 1990-7% 2005 Cases, 2020

## Coal Mining and Oil and Gas Industry Employment, 1970-2020

## Uncertainties

- Impacts on Technology Costs
- Timing of Scenarios
- Response of Market Participants, Both Industry and Consumers
- Reliability and Volatility
# Presentation: 018728

## Lead in Pharmaceutical ProductsBackground and Introduction

- Norman R. Schmuff, Ph.D.
- Office of New Drug Quality Assessment
- ACPS-CP Meeting
- July 22, 2008

## Desired AC Outcome

- Identify what, if any further steps should be taken by the Agency regarding lead content in drug products.

## Albemarle’s Docket SubmissionLetter of Aug 28, 2003

- Related to Tentative Final Monograph for ibuprofen (IB) NDA  Monograph
- Raised the issue of lead in foreign-sourced ibuprofen drug substance
- Reported results from testing of IB
- Tested 30 products
- For 1200 mg max daily dose of IB
- 14 US — from “Not Detected” to 1.25 micrograms
- 16 foreign — from “Not Detected” to 13 micrograms

## Dept of Veterans Affairs

- Requested FDA testing of IB in 2003
- Tested 11 samples from two suppliers
- Five samples less than limit of detection
- Highest finding 0.25 ppm in one sample(0.3 micrograms per day for 1200 mg IB)

## Ibuprofen USP Lead Limits

- Ibuprofen
- 6 x 200 mg (1200 mg)
- 0.002% heavy metals limits USP 31–NF 26
- Excipient*
- 6 x 300 mg (1800 mg)
- 0.003% heavy metals limits USP 31–NF 26
- Result is 78 micrograms daily intake

- *Assume any of the calcium phosphates in USP-NF

## Regulatory Pb Limits

|  | ppm(mg/L or mg/kg) | Max daily intake (μg) |
| --- | --- | --- |
| USP (Pb)	(Heavy Metals) | 2 to 50 0.2 to 100 | 40 to 1000* 4 to 2000* |
| CDER | none(see next slide) | none(see next slide) |
| CFSAN (candy) | 0.1 | 5** |
| EPA (water) | 0.015 | 30 |
| EU (foods) | 0.05 to 1.0 | 50 to 1000 |

- *based on 20 g daily drug intake

- **based on 50 g daily candy intake

## CDER Pb Controls

- Indirect via USP/NF monographs
- Drug substance (~50% of 1213)
- Excipients (~50% of 397)
- Drug product (3% of 2254)
- Generally no additional controls expected, unless the product contains metals other than Na or K

## FDA’s 1993 Provisional Tolerable Total Intake Levels (PTTIL)

| Population | PTTIL(μg Pb / day) |
| --- | --- |
| Children aged 0 to 6 years | 6 |
| Children over 7 years | 15 |
| Pregnant women | 25 |
| Adults | 75 |

## Hypothetical Exposure to Lead for Adults as Affected by Drugs

## Working Group

- Offices
- Office of New Drugs (Div Pediatric Drug Dev)
- Office of New Drug Quality Assessment
- Office of Pharmaceutical Science
- Office of Non-Prescription Products
- Risk-based sampling plan
- Mined components (non-alkali metals)
- Used in pediatric population
- High volume product

## Lead in a Multivitamin (2007) 

- Vitamin Shoppe Multivitamins “Especially for Women”
- Reported to have 15 micrograms of lead in two tablets
- CFSAN collected more than 300 samples of vitamins/minerals
- Preliminary analysis indicated no significantly elevated levels of lead

## Agenda

## ACPS-CP QuestionsLead in Pharmaceutical Products

- What additional information would be necessary for us to gather to appropriately determine the next steps?
# Presentation: 789961

## MODLAND Science Testing Status

- MODIS Land Science Team Workshop
- July 15, 2003
- Robert Wolfe
- MODIS Land Team Support GroupNASA GSFC Code 922, Raytheon ITSS

## Science Testing Status (1/2)

- Test system performance is 2X
- Four tests performed before start of Terra C4
- MODLAND participated in 13 tests since C4 start
- 9 for land only (includes 2 repeated)
- 4 to evaluate downstream impacts of L1/atmosphere changes
- currently two MODLAND tests underway with one scheduled
- Science team response: good

- July 15, 2003  –  MODLAND Workshop  –  R. Wolfe

## Science Testing Status (2/2)

- Currently formalizing test design process
- Deciding on and saving a comparable test data set has been a challenge
- Global browse for science testing is valuable
- More SCF testing needed in some cases
- Additional time-series test is needed
- should be at least a year
- focus on LDOPE golden tiles augmented with a few recommended by SCFs (10 tiles)
- LDOPE time series plots would be helpful for analysis

- July 15, 2003  –  MODLAND Workshop  –  R. Wolfe
# Presentation: 666281

## NOAA's NWS National Performance Measures FY 2005 – FY 2011

| Government Performance Requirements Act
(GPRA) Performance Measure | Goals | Actual  | Goals |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- |
|  | 2005 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 |
| Tornado Warnings - Accuracy (%) | 73 | 75 | 76 | 76 | 76 | 76 | 76 | 76 |
| Tornado Warnings - False Alarm Rate (%) | 73 | 77 | 75 | 74 | 74 | 74 | 74 | 74 |
| Tornado Warnings - Lead Time (Min) | 13 | 13 | 13 | 14 | 15 | 15 | 15 | 15 |
| Flash Flood Warnings - Accuracy  (%) | 89 | 88 | 89 | 90 | 90 | 90 | 90 | 90 |
| Flash Flood Warnings - Lead Time  (Min) | 48 | 54 | 48 | 49 | 49 | 49 | 49 | 49 |
| Winter Storm Warnings - Accuracy  (%) | 90 | 91 | 90 | 90 | 90 | 91 | 92 | 92 |
| Winter Storm Warnings - Lead Time  (Hours) | 15 | 17 | 15 | 15 | 15 | 16 | 17 | 17 |
| Hurricane Track Forecasts (48 Hours Forecast Error, Nautical Miles) | 128 | 99* | 111 | 110 | 109 | 108 | 107 | 106 |
| Aviation Forecasts (Ceiling & Visibility) - Accuracy (%) | 46 | 46 | 47 | 48 | 51 | 52 | 53 | 59 |
| Aviation Forecasts - (Ceiling & Visibility) False Alarm Rate (%) | 68 | 63 | 65 | 64 | 58 | 57 | 56 | 50 |
| U.S. Seasonal Temperature – Skill | 18 | 19 | 18 | 19 | 19 | 19 | 20 | 20 |
| Precipitation Forecast – Day-1 Threat Score  (%) | 27 | 29 | 28 | 29 | 29 | 29 | 30 | 30 |
| Marine Wind Speed Forecasts - Accuracy  (%) | 57 | 57 | 58 | 58 | 58 | 59 | 59 | 59 |
| Marine Wave Height Forecasts - Accuracy  (%) | 67 | 67 | 68 | 68 | 68 | 69 | 69 | 69 |

**Preliminary; will be finalized 2**nd** quarter FY 06*

## Tornado Warnings

## Flash Flood Warnings

## Winter Storm Warnings

## Hurricane Track Forecasts (48Hrs)

- *Note: FY05 Actual is preliminary

## Aviation Forecasts(Ceiling/Visibility Forecast 3 Mile/1000 ft.)

## U.S. Seasonal Temperature - Skill

## Precipitation Forecast(Day-1 Threat Score)

## Marine Wind Speed Forecasts 

## Marine Wave Height Forecasts
# Presentation: 270958

## NIST/ASME Thermophysical Properties of Water Database

**Water/Steam**
**Ubiquitous in industry and science as solvent, calibration fluid, thermal transport fluid, working fluid in evaporative/condensation cycles, hydrological cycles, etc. **
**Improved representation of thermo-dynamic properties, especially in critical region and for supercooled liquid; based on ITS-90**
**New formulation for thermodynamic properties adopted; NIST to provide U.S. implementation of new standard**
**revision and replacement of old STEAM tables**
**Designed for easy incorporation into other software**
**distribution agreement with Aspen Technology, Inc.**

*** “******Combined-Cycle” Power Plant***
***Mojave Desert, California***

**NIST/ASME Thermophysical Properties of Water Database**

## Structure and Dynamics of Silica Gels

**Sol-gel technology can produce**
- ceramics at low temperatures
- high-purity materials with unique compositions and properties (*e.g*., superconductors, insulators)
- glasses of designed porosity
- containers for special purposes (*e.g*., nuclear and chemical waste storage)
**Advances in industrial & scientific applications require basic understanding of structure and dynamics of high-density silica gels**
- performed Small Angle Neutron Scattering to probe the gel structure and aggregation process on nanometer scale
- observed temporal self-similarity; used dynamic self-scaling relationship to improve model of aggregating system