# Presentation: 685977

## Budget ConsiderationsCenters for Medical Countermeasures Against Radiation (CMCR) 

- Gregory Smith
- NIAID Grants Management
- 301-451-2686
- gs225y@nih.gov

## Centers for Medical Countermeasures Against Radiation (CMCR)

- Plan to fund 6 to 8 CMCR
- $28 Million available for the entire program in FY 2005
- Applicant may request a project period up to 5 years and a budget for total cost (includes F&A) up to $5 million per year
- Mechanism of Support – NIH (U19) Cooperative Agreement Award Mechanism
- Letter of Intent due:  January 24, 2005
- Application Receipt Date: February 22, 2005
- Earliest Possible Award Date: September 2005

## Centers for Medical Countermeasures Against Radiation (Structure)

- Each CMCR application must include the following components:
- Center Management and Operations including an Administrative Core
- Research and Development Projects
- Pilot Research Projects Program (Core)
- Scientific Cores (if needed)
- Training and Education Program (Core)
- Separate detailed budget page for each component (Pages 4 & 5)

## Page 4

- 398 Kit

## Page 5

- 398 Kit

## Center Management and Operations including Administrative Core

- The Administrative Core must submit detailed budget page (Pages 4 and 5)
- Administrative Core must include:
- 10% effort of the CMCR Principal Investigator
- Any proposed Alterations & Renovations must be included in the Administrative Core budget – one time max of $300,000 total cost allowed

## Research/Development Projects

- At least 3 R01-type Research/Development Projects
- Focused on product development
- Clinical trials beyond Phase 1 trials will not be supported by this program

## Research/Development Projects

- Research/development project must include :
- 	 -  face page
- 	 -  PHS 398 Form Page 2
- An individual budget for the initial budget period (Page 4)
-  A budget for the entire proposed period of support (Page 5)
- If project includes a consortium a separate PHS 398 Face page, Page 4 and 5 for the consortium must be included.

## CONSORTIUM

## Pilot Research Program (Core)

- Submit detailed budget page (pages 4 & 5)
- Must submit concept budget estimates or it may be left out of the budget
- Specific number of Pilot Research Projects to be funded at discretion of the applicant
- Total funding for these projects may not exceed $500,000 direct cost in any one year, with no more than $100,000 annual direct cost for any one study
- Each Research Pilot Project may be supported for no more than 2 years

## Scientific Core (if needed)	

- Must submit detailed budget page (pages 4 & 5)
- Scientific facilities to support the Research/Development Projects if they will be utilized by at least two (2) of the Research/Development Projects
- Core funds need prior approval for re-budgeting within the CMCR

## Training and Education Core	

- Must submit detailed budget page (pages 4 and 5)
- Proposed training and education programs should be multidisciplinary and provide short-term education for technicians, medical or graduate students, postdoctoral fellows, and/or independent investigators, either within or beyond the CMCR

## Composite Budget for the Entire Application

- Except for the information that contradicts the instructions provided today use “The Instructions for Applications for Multi-project Award”at _[http://www.niaid.nih.gov/ncn/grants/ ](http://www.niaid.nih.gov/ncn/grants/)__ as guidance._

## Other Important Information

- Any domestic institution can apply
- For-profit or non-profit
- Foreign institutions are _not eligible_ to apply but may be members of consortia headed by US institutions
- Public or private research institutions, universities, colleges, hospitals or laboratories
- Fiscal and administrative cost _are_ included in the 5 million dollar cost cap
- Federal Agencies that are not part of the HHS appropriation can apply
- Agencies that are part of the HHS appropriation can be collaborators without compensation (includes NIH intramural labs, CDC, etc.)

## Other Important Information (cont) 

- Intellectual Property Rights
- NIH policy that results/accomplishments with NIH funds should be made available to the public
- If research results in inventions, see the NIH Grants Policy Statement. Other related references include:
- Bayh-Dole Act of 1980, as implemented in 37 CFR Part 401
- Technology Transfer Commercialization act of 2000 (P.L. 106-404)

## Intellectual Property Rights (cont)

- NIH grantees may retain intellectual property rights to subject inventions provided they do the following:
- Report all inventions to NIH
- Make effort to commercialize the subject invention through patent or licensing
- Formally acknowledge the Federal government’s support in all patents that arise from the subject invention
- Formally grant the Federal government a limited use license to the subject invention
- While not stated specifically in the RFA, consortium partners should develop an intellectual property plan at the time of award

## Assembly of Application

- Please carefully follow in assembly instructions outlined in the RFA
- Provide a face page for the overall CMCR, as well as each, core, project, subject project, consortium partner, pilot project, etc.