# Presentation: 000329

## NATIONAL CANCER INSTITUTE

- <date/time>

**DIAGNOSTIC IMAGING PROGRAM**

**NATIONAL CANCER INSTITUTE**

## National Institutes of HealthNational Cancer Institute

**Diagnostic Imaging Program**

## Diagnostic Imaging Program: Update

**Money**
**Organizational comments**
**Current Programs**
**Future Plans**
**Concluding comments**

## NIH Funding for Imaging

- <date/time>

**NIH Funding for Imaging**

- $Millions

## DIP Grant Funding

- <date/time>

**DIP Grant Funding**

**$M**

## Diagnostic Imaging Program(DIP)

- <date/time>

**Diagnostic Imaging Program(DIP)**

**Diagnostic**
**Imaging**
**Branch**

**Functional**
**Imaging**
**Branch**

**Image-guided**
**Therapy**
**Branch**

**Office of**
**Imaging**
**Technology**

**Division of Cancer Treatment and Diagnosis**
**(DCTD)**

**Cancer**
**Diagnosis**
**Program**
**(CDP)**

**Develop-**
**mental**
**Therapeutics**
**Program**
**(DTP)**

**Cancer**
**Therapy**
**Evaluation**
**Program**
**(CTEP)**

**Radiation**
**Research**
**Program**
**(RRP)**

**NCI**

## Organization

**10 FTE’s**
**D Sullivan, L Clarke, J Hoffman, A Menkens, B Croft, M Torres, J Smith, L Cooley, S Bowles, L Banh**
**3 Part-time**
**E Staab, J Tatum, C Langlotz**
**Further expansion is space limited**

## Positions available(of importance to imaging)

**NCRR Director of Bioengineering**
**NHLBI Program Director**
**NCI Scientific Review Administrator**

## Radiology 1999; 212:609-614

## Recent Programs

## Current Programs(1)

## Current Programs(2)

## Collaborative Programs

## CTEP Collaborative Programs

## DIP Standards Activities

**DICOM / Working Group on Clinical Trials Data**
**RSNA - IHE / RSNA - image archive collaborations**
**Structured reporting collaborations: DICOM, SNOMED, ACR, RSNA**
**Image database standards: RFA**

## NCI - Imaging Industry Relations Forum

**Clear description of HCFA decision rules**
**Policy for conditional coverage of emerging imaging technologies**
**Re-evaluation of FDA policies, esp. re: tracers or procedures of low risk**
**Assure full range of NCI support mechanisms for imaging science.**

## NCI Training Activities

## R 25

**Cancer Education and Career Development Program**

## R 25  Cancer Education and Career Development Program

**Multidisciplinary**
**Institutional award**
**Salary support for PI and core faculty**
**Trainee salary up to ****$75,000**
**Research support up to**** $20,000**** per trainee**
**5 yr. grant, renewable**
**8% indirect**

## K07 / K08 / K23

**K 07 Epidemiology**
**	**** ****(limited use by radiology)**
**K 08 Clinician:  Bench science**
**	****(limited use by radiology)**
**K23 Clinician:  Patient-oriented (hands-on; obtain consent form)**
**	****(no imaging applications yet)**
**Salary ****$75,000****/ Research ****$30,000**

## T32 Training Grants - Imaging

**From ****1/97-10/99   (6 NCI deadlines)**** **

**•  ****6.5% of applications submitted were ****	****	****imaging-related**

**•  ****57.1% of imaging-related T32s **
**	****       ****were funded**

**•  ****54.2% of T32 applications submitted to ****	****       NCI were funded **

## T32 Training Grants - Imaging

_**Yrs**__**	**__**PI**__**	**__**Title**_**	**
** ****24****	****Kuhl, David****	****Cancer Research Training in Nuclear Medicine**
** ****17****	****Wagner, Henry****	****Res. Training in Use of Tracer Principles in Oncology**
** ****14****	****Brady, Thomas****	****Nuclear Magnetic Research**
** ****10****	****Zerhouni, Elias****	****Research Training in Oncology Imaging**
**  ****7****	****Glazer, Gary****	****Advanced Techniques for Cancer Imaging**
**  ****5****	****Clouse, Melvin****	****Deaconess Research Training in Cancer Radiology**
**  ****4****	****Baum, Stanley****	****Training in Innovative Cancer Imaging Technologies**
**  ****3****	****Hawkins, Randall****	****Research Training in Diagnostic Oncology**
**  ****2****	****Wehrli, Felix****	****Training in Quantitative Magnetic Resonance Imaging**
**	****	****	****	**
** ****23****	****Hoffman, Edward****	****Research Training in Biomedical Physics**
** ****23****	****Bedford, Joel****	****Radiological Sciences Basic to Cancer Research **
** ****21****	****DeLuca, Paul****	****U.W. Radiological Sciences Training Program**
** ****18****	****Alpert, Nathaniel****	****Postgraduate Program in Radiological Science**
** ****10****	****Doi, Kunio****	****Research Training in Medical Physics**

## Research Training Grant Information

**Call Brian Kimes**
**	****301 496 8537**
**email:**
**	****bk34t@nih.gov**

## Future Plans - Devices

**Proposed PA: R21/R33 for imaging technology development**
**RFP for ultrasound research interface**
**RFA for spiral CT image database**
**Proposed program to support production of beta units for clinical trials**
**Proposed additional Centers with technology development component**

## Future Plans - Pharmaceuticals (Imaging agents)

**Pharmaceutical categories of interest:**
**1. Non-PET tracers**
**2. PET tracers**
**3. Bulk agents (pharmacologic effect)**
**4. Radiolabeled therapeutic agents (non-sealed-source agents)**

## Future Plans - Pharmaceuticals (Imaging agents)

**Proposed program to support development of novel imaging probes.**
**Proposed program to support R & D necessary for IND, and provide supply needed for clinical trials.**

## Concluding Comments

**Molecular imaging**** is future priority**
**DIP funding increased 40 %**
**More applications lead to more funding**
**Patient accrual needs attention**
**Rewards for team science need attention**
**Think ****R25**** for research training grants **

## Sources of NCI imaging information to public

**Website: URL = www.nci.nih.gov/dip/**
**Email Newsletter **

## Handouts available

**URLs of interest**
**Training program information**
**Copy of Acad Rad article: Radiologic Sciences Research in the Next Century**
**DIP Newsletter**
**Everything you ever wanted to know ...**
**Cancer information pamphlets**