# Presentation: 567681

- Toxicological Data System

- CDR Gary Perlman, US Public Health Service
- Agency for Toxic Substances and Disease Registry
- 7May2008

## Toxicological Data System: PDAs

**Data System Overview**
**PDA Overview**
**Resources**
**Usage**
**Hardware/software**
**Contacts**

## Toxicological Data System: PDAs

**Developed shortly after 911 for field use w/out need for laptop or internet**
**Ready reference of toxicological emergency values**
**Used in USA, CA, FR**
**Used by USCG, EPA, others...**

## PDA Overview

**PDA Overview**

**Icons are Programs**
**Programs Loaded****by Tapping**

## PDA Overview

**PDA Overview**

**Field Use***** ***
*** ***
*Assist**** - EPA (Chemical spills)***
*Inform**** - First Responders (share data)***
*Reply**** - to Citizen’s request at Meetings***
*Prepare**** - phone, fax, email list***

- Share data via infrared beam

## Resources

**One database contains the following:**
**AEGLs (Exposure Guideline Levels)**
**ATSDR Toxicological Profiles (full text-172 chemicals)**
**ATSDR ToxFAQs (1 page summary-172 chemicals)**
**ATSDR Medical Management Guides for Acute Exposures to Chemicals MMGs (50 chemicals)**
***DOE PACs***
**EPA Risk Based Concentrations (RBC), Preliminary Remediation Goals (PRG)**
**EPA IRIS database (560 chemicals)**
**Occupation Levels**
**NIOSH RTECS: Registry of Toxic Effects of Chemical Substances **

## Resources (cont.)

**These resources are saved as individual databases:**
**AFRRI Medical Mgmt of Radiological Causalities**** **
**ATSDR Risk Communication Primer**** **
**DOT Emergency Response Guidebook, and Spills (as a stand alone database)**** **
**National Library of Medicine’s HSDB (Hazardous Substances Data Bank for 5,000 compounds)**** **
**USAMRIID Handbook Medical Mgmt of Biological Casualties**** **
**USAMRICD Handbook Medical Mgmt of Chemical Casualties**

## Hardware

- PDA with SD slot

- 256 MB SD card

- SD card Reader/Writer

## Software

- iSilo Document reader ($20) www.store.isilo.com

## Anthrax Decontamination, ClO2 Dec2007 – Danbury, CT

- Containment Breach Scenario
- What is IDLH (5ppm)
- What is Community Level (0.001ppm)

## Databases

- Every database is an iSilo “document”
- The file you will use most is called: “Toxicological data for PDAs”
- Other iSilo document include: HSDB, ERG2004, and Medical Management of... Biol, Chem, Rad Casualties; Risk Communication Primer; and Environmental Glossaries (English and Spanish)

## Usage

- Tap the iSilo icon

## Usage

**Tap on the database name to open it.**

## Usage

**Usage**

**Tap on the database name to open it.**

**This is the main database**

**These are the Bio, Chem, Rad, Casualties Guides**

**This is the Emergency Response Guide**

## Slide 15

## Medical Management Guides

## Medical Management Guides

## Toxicological Profiles

## Toxicological Profiles

- Hyper-Links from Table of Contents.

## ToxFAQs

## Risk Communication Primer

## Hazardous Substances Data Bank (HSDB)

**Hazardous Substances Data Bank (HSDB)**

## Hazardous Substances Data Bank (HSDB)

**Hazardous Substances Data Bank (HSDB)**

## DOE’s Protective Action Criteria

## Medical Management of Biological Casualties

**Medical Management of Biological Casualties**

## Medical Management of Biological Casualties

**Medical Management of Biological Casualties**

## Medical Management of Chemical Casualties

## Medical Management of Chemical Casualties

**Medical Management of Chemical Casualties**

## Medical Management of Radiological Casualties

## Medical Management of Radiological Casualties

**Medical Management of Radiological Casualties**

## RTECS

## Usage

- Tap the iSilo icon

## Usage

**Usage**

**Tap on the main database: **
**Toxicological data for PDAs**

## Usage

**Usage**

**Tap on **_Introduction_

## Usage

**Usage**

**Tap on ** _Go to Top_ **to return to the start page.**

## Usage

**Usage**

**Tap on** _Table of Contents_

## Usage

**Usage**

**Tap on the first character of the chemical (e.g. **_B_**)**

## Usage

**Usage**

**Tap on the first three characters of the chemical (e.g. **_Ben_**)**

## Usage

**Usage**

**Scroll **_Up_**or**_Down_** ****to locate the chemical.**
**You can also **_**tap and hold**_** the stylus in the WHITE area to drag the page either up or down.**

## Usage

**Usage**

**Tap on the database (e.g. **_AEGL_**)**

## Usage

**Usage**

**AEGL definitions**

## Usage

**Usage**

**AEGL data**

## Usage

**Usage**

**AEGL data (cont...)**

## Usage

**Usage**

**IRIS**

## Usage

**Usage**

**IRIS RfD summary**

## Usage

**Usage**

**IRIS RfD summary**

## Usage

**Usage**

**Medical Management Guides (MMG)**

## Usage

**Usage**

**Medical Management Guides (MMG)**

## Usage

**Usage**

**Minimal Risk Levels (MRL)**

## Usage

**Usage**

**Minimal Risk Levels (MRL)**

## Usage

**Usage**

**Occupational Standards**

## Usage

**Usage**

**Occupational Standards**

## Usage

**Usage**

**Immediately dangerous to Life and Health (IDLH)**

## Usage

**Usage**

**Immediately dangerous to Life and Health (IDLH)**

## Usage

**Usage**

**Preliminary Remediation Goals  (PRG)**

## Usage

**Usage**

**Preliminary Remediation Goals  (PRG)**

## Usage

**Usage**

**Risk Based Concentrations (RBC)**

## Usage

**Usage**

**Risk Based Concentrations (RBC)**

## Usage

**Usage**

- REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES** (**RTECS )

## Usage

**Usage**

- REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES** (**RTECS )

## Usage

**Usage**

- Protective Action Criteria (PAC)

## Usage

**Usage**

- Results are displayed in mg/m3 and ppm

## Usage

**Usage**

- Definitions for each PAC level...

## Usage

**Usage**

- ToxFAQ

## Usage

**Usage**

- ToxFAQ

## Usage

**Usage**

- Toxicological Profiles

## Usage

**Usage**

- Toxicological Profiles

## Usage

**Tap on the database name to open it.**

**This is the Emergency Response Guide**

## Usage

**Usage**

- Emergency Response Guidebook

## Usage

**Usage**

- Emergency Response Guidebook

## Usage

**Tap on the database name to open it.**

**Hazardous Substance DataBank**

## Usage

**Usage**

- HSDB

## Usage

**Usage**

- HSDB

## Usage

**To return to the Start Page (with the main table of contents), tap the **_Home icon_**.**

## Usage

**To go to the previous page, tap on the **_Left arrow_**.**

## Usage

**To close the database, tap on the **_X_**. Note: the next time you open the database, it will return to the location that was viewed when you tapped on the **_X_**. It is a good idea to always tap on the **_Home icon_**, then close the database.**

## Usage

**To search for text, tap on the **_**magnifying glass**_** icon.**

## Backing-up Data

- Place PDA in cradle
- Connect to USB port on Computer
- Press HotSync Button

## Updates

- Insert the update CD.
- Insert the 256MB SD card.

## Updates

- Remove the 256MB SD card manually.

## Hardware

- PDA with SD slot

- 256 MB SD card

- SD card Reader/Writer

## Desktop versions- HSDB

## Selecting a Chemical

**Start typing the initial letters for the chemical for which you seek information. Then click on the chemical name.**

## Selecting a Chemical

**Selecting a Chemical**

**All fields that are available for this chemical will be bolded, those fields unavailable will be shaded.**

## Selecting a Chemical

**Selecting a Chemical**

**Select the information from any category by clicking on the drop-down box, and selecting the title (****e.g., Evidence for Carcinogenicity****).**

## Selecting a Chemical

**Selecting a Chemical**

**The information is then listed in the main box to the right.**

## Selecting a CASN

**Selecting a CASN**

**Start typing the numbers of the CASN for the chemical for which you seek information. Then click on the CASN that matches.**

## Selecting a CASN

**Selecting a CASN**

**Select the category, and title. **

## Selecting a CASN

**Selecting a CASN**

**The information will be displayed on the box to the right.**

## Exporting Data

**Exporting Data**

**Click on the button labeled “Export Data” to save data for this chemical (you then will be asked for a file name and which fields to export).**

## Exporting Data

**Exporting Data**

**Select the fields to export, then click on the button labeled “Export selected fields”).**

## Exporting Data

**Exporting Data**

**In order to select all fields for exporting, click on the button labeled “Export all fields”.**

## Exporting Data

**Exporting Data**

**Enter the file name for the exported data, then click on the button labeled “Save”.**

## Exporting Data

**A confirmation dialog box will be displayed confirming that the data were exported.**

## Desktop versions-PACs

## PACs database (draft)

- Select by chemical or CASN

## PACs database (draft)

- Start typing chemical and select from list

## PACs database (draft)

- Values are then displayed

## PACs database (draft)

- Common units and molecular wt are displayed

- mg/m3

- }

- ppm

- }

## PACs database (draft)

- Click on the Definitions button for description.

## PACs database (draft)

- Definitions

## PACs database (draft)

- The notes describe the basis for the each PAC.
- e.g.,
- TEEL-0 is based on PEL
- PAC-1 is based on AEGL-1
- PAC-2 is based on AEGL-2
- PAC-3 is based on AEGL-3

## PACs database (draft)

- Click Exit to quit

## Contact Information

**CDR Gary D. Perlman MPH, RS, EMT-B**
**ATSDR-New England,**
**US Public Health Service**
**Voice: 617-918-1492    **
**Fax: 617-918-1494**
**Email: **_[GAP6@CDC.GOV](mailto:GAP6@CDC.GOV)_