# Presentation: 097239

## National Cancer Institute

- Dedicated to discovery aimed
- at the eradication of cancer

## NCI SBIR/STTR Budgets

**SBIR**
**FY 99****	****FY 2000**
- $55.8M	$63.7M

**STTR**
**FY 99****	****FY 2000**
- $3.4M	$3.8M

**Notes:**
Phase I applicant is non-profit organization
 Applicant must partner with for-profit small business who agrees to prepare the Phase II application.
Utilizes R25 (Cancer Education and Career Developoment Grant, and FastTrack SBIR grant (R44)
 PI for R25 must be retained

## NCI’S Interests

- Investigator-initiated research
- NCI Scientific Priorities
- Extraordinary Opportunities
- Targeted Initiatives

## NCI: Dedicated to Discovery

- Nature of Cancer: What is cancer and how does it develop?
- Cancer Risk: Who is at risk and why?
- Prevention: How can cancer be prevented?
- Detection: How do we screen for, detect, and diagnose cancer?
- Treatment: How is a given cancer best treated?
- Rehabilitation: How might the quality of life for cancer patients and survivors be improved?

- Key Questions About Cancer

## Slide 5

## NCI Extraordinary Opportunities

-    Areas where focused efforts and increased resources could produce dramatic progress toward reducing the burden of cancer

## Extraordinary Opportunities:Fiscal Year 2001

- Genes and the Environment
- Cancer Imaging
- Defining the Signatures of Cancer Cells: Detection and Diagnosis
- Molecular Targets of Prevention and Treatment
- Research on Tobacco and Tobacco-Related Cancers
- Cancer Communications

## Small Business Opportunities 

- Development of Novel Imaging Technologies (PAR-00-090)
- Molecular Target Drug Discovery for Cancer (NCI-PAR-00-061)
- Flexible System to Advance Innovative Research for Cancer Drug Discovery by Small Business (PAR-00-030)
- Diagnostic Imaging and Guided Therapy in Prostate Cancer (NCI-PAR-99-149)
- Cancer Communication and Interactive Media Technology (NCI-PA-99-141)
- Applications of Innovative Technologies for the Molecular Analysis of Cancer (NCI-PAR-99-103)

- http://www.cancer.gov/tech/small_fund.html

## Opportunities (con’t.)

- Innovative Technologies for the Molecular Analysis of Cancer (NCI-PAR-99-101)
- Development of Digital Mammography Displays and Workstations (NCI-PA-99-083)
- Technology to Improve the Utility of Animal Models (PA-99-048)
- Non-mammalian Organisms as Models for Anticancer Drug Discovery (NCI-PAR-99-020)
- Engineered Isogenic Cell Lines with Relevant Cancer Targets (NCI-PA-98-068)

- http://www.cancer.gov/tech/small_fund.html

## PAR-00-030:  Flexible System to Advance Innovative Research for Cancer Drug Discovery by Small Business (FLAIR)

**Objective**: Provide a flexible funding opportunity for cancer drug discovery from basic discovery through clinical evaluation
**Unique Features:**
- Special receipt dates (Nov 22, 2000)
- Review by NCI Division of Extramural Activities
- Additional review considerations
- Flexible budget and time specifications
- $250K per year.
- 2-year Phase I, 4-year Phase II

## NCI-PA-99-141:  Cancer Communication and Interactive Media

**Objective**: Promote collaborations between non-profit organizations and for-profit small businesses in the area of communication and interactive media
**Unique Features:**
- Alternative funding mechanism (R25 & R44)
- Provides second phase support of innovative research initiated by R25
- Project duration (4 years)
- R25--12 months
- R44, Phase I--6 to 12 months
- R44, Phase II--2 years

**Notes:**
Phase I applicant is non-profit organization
 Applicant must partner with for-profit small business who agrees to prepare the Phase II application.
Utilizes R25 (Cancer Education and Career Developoment Grant, and FastTrack SBIR grant (R44)
 PI for R25 must be retained

## PAR-99-101: Innovative Technologies for the Molecular Analysis of Cancer: SBIR/STTR Initiative

**Objective:** Provide opportunity to develop novel technologies to support molecular analysis of cancers
**Unique Features:**
- Runs parallel in scope with PAR-99-100
- Special receipt dates (Jul 21, Nov 21, 2000, and Mar 21, 2001)
- Review by NCI Division of Extramural Activities
- Flexible budget and time specifications
- Phase I, up to 2 years, $100K per year
- Phase II, up to 3 years, no official budget limit

**Notes:**
Phase I applicant is non-profit organization
 Applicant must partner with for-profit small business who agrees to prepare the Phase II application.
Utilizes R25 (Cancer Education and Career Developoment Grant, and FastTrack SBIR grant (R44)
 PI for R25 must be retained

## Slide 13

## Slide 14

## NCI Resources

- SBIR/STTR (http://www.cancer.gov/tech/small_biz.html)
- OTIR (http://www.cancer.gov/OTIR)
- By-Pass Budget (http://2001.cancer.gov/2001.htm)
- NCI initiatives (http://www.cancer.gov/initiatives/)
- NCI home page (http://www.cancer.gov)
- Resources (http://resresources.nci.nih.gov/)
- NCI SBIR/STTR Coordinator:
- 	Kay Etzler (301) 496-1550
- 	etzlerk@mail.nci.gov

**Notes:**
Phase I applicant is non-profit organization
 Applicant must partner with for-profit small business who agrees to prepare the Phase II application.
Utilizes R25 (Cancer Education and Career Developoment Grant, and FastTrack SBIR grant (R44)
 PI for R25 must be retained