# Presentation: 265064

## The Application Process

**The Application Process**

*Jean L. Flagg-Newton, PhD*
*Program Director*
*Office of Capacity Building and Infrastructure*

## Definitions

- Applicant Institution
- Collaborating Institution
- Complementary Applications
- Complementary Budget

## Selecting the Funding Mechanism

- R24: Resource Related Research Grant
- Four-year Institutions
- Four-year Institutions @ Masters Degree Programs

- RESEARCH PROGRAMS ARE GENERALLY DEVELOPMENTAL AS DETERMINED BY EXISTING RESEARCH SUPPORT

## Selecting the Funding Mechanism

- P20: Exploratory Grant
- Have not had a comprehensive (P60) or specialized center (P50) grant funded by other NIH institutes and centers
- Eligible for support by the NCRR COBRE Program

**DEVELOPMENT OF INTERDISCIPLINARY PROGRAMS THAT OFFER POTENTIAL SOLUTIONS TO PROBLEMS OF SPECIAL SIGNIFICANCE TO NCMHD**

## Selecting the Funding Mechanism

- P60: Comprehensive Center
- Have had NIH support through either the P60 or P50 mechanisms

- INSTITUTIONS WITH SUBSTANTIAL FEDERAL FUNDING SUPPORT AS JUDGED BY THE 1998 REPORT ON RESEARCH INSTITUTIONS

## Complementary Applications

- The Face Page
- Item 7a: Combined Direct Costs of Partnering Institutions
- Item 7b: Combined Total Costs of Partnering Institutions

## Application Process

- Performance Site (Form Page 2)

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Biographical Sketches

- All professional personnel & consultants with percent effort – applicant/collaborating institutions
- Arrange alphabetically
- Do not duplicate in individual component cores/pilots

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Participating Faculty

- Provide listing in tabular format:
- Name including degree
- Institution and department affiliation or equivalent
- Research or other interest (e.g., research component area, shared resource core, training, etc.)

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Resources

- Resources format page
- Describe, by institution, the relevant resources available to the proposed export center/program

- IDENTICAL IN COMPLEMENTARY APPLICATION

## Overview/Description of EXPORT Center

- Describe scientific area of inquiry
- Specific aims and objectives
- Research
- Training
- Community outreach
- Infrastructure development (if applicable)

- IDENTICAL IN COMPLEMENTARY APPLICATION

## Overview/Description of EXPORT Center

- Background and Significance
- 25-page limit
- Establish the significance of proposed center’s objectives (critical review/ synthesis of relevant research, theory, methods)
- Rationale and justification for the proposed institutional partnership (emphasizing how each institution will contribute and benefit)
- Plans to develop productive collaborations

## Overview/Description of EXPORT Center

- Background and significance (cont’d)
- Preliminary studies
- Provide detailed description/discussion of funded research projects that constitute the proposed center’s research base
- Establish relevance to minority health/health disparities issues and strengths and limitations of scientific foundation of specific aims

## Overview/Description of EXPORT Center

- Background and Significance (cont’d)
- Present preliminary studies in tabular format
- Names  and institutional affiliation of the PI
- Study title and grant number
- Percent effort
- Funding organization
- Period of committed support
- Direct costs for project period
- Current annual year direct costs
- May also present non-related funded research In tabular format

## Overview/Description of EXPORT Center

- Background and Significance (cont’d)
- Also include the following:
-  A description of the qualifications of the center director and co-director
- General plans for collaborations between the partnering institution

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Administrative Core

- 15 page limit
- Provide the following:
- Detailed description/discussion of the objectives, functions, and organizational infrastructure, administrative procedures
- Key personnel, including core director
- Relationships and lines of authority by appropriate officials at partnering institutions
- Diagram showing integration of export center in institution’s administrative structure

## Administrative Core (cont’d)

- Also provide the following:
- Plans for assistance of a business official for fiscal matters
- Resources of the administrative core
- Committee structure, including a description of the qualifications for membership
- Discuss the institutional commitment and include letter(s) of commitment

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Shared Resource Core(s)

- 15 page limit
- Provide detailed description/discussion:
- Objectives, functions, organizational infrastructure
- Administrative procedures, key personnel, including the core director
- Resources of the shared resource core within context of overall center

**SHARED FACILITIES THAT PROVIDE NEEDED SERVICES TO CENTER INVESTIGATORS ENABLING THEM TO CONDUCT THEIR FUNDED INDIVIDUAL RESEARCH PROJECTS MORE EFFICIENTLY AND MORE EFFECTIVELY.**

## Shared Resource Core(s) (cont’d)

- Also:
- Delineate shared resource(s) to be provided at each participating institution
- Describe relationships and lines of authority at the partnering institutions
- If charge back system developed to help defray cost - provide justification for charge

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Research Component Core(s)

- May establish multiple, interrelated research component cores, if feasible
- Each core should have a director and may include several investigators
- Conditions for establishing a research core: strong research base in an area(s) of emphasis
- Can include research at other institutions if collaborations exist with scientists at applicant institution

## Research Component Core(s) (cont’d)

- Provide the following:
- Overview of area of emphasis – provide in sufficient detail to allow reviewers to judge relevance to minority health/health disparities
- Detailed description and discussion of the specific aims/objectives as related to addressing health disparities
- Indication of how center will provide added dimensions (e.g., greater focus and increased cooperation, communication and collaboration)

- 15-PAGE LIMIT PER RESEARCH COMPONENT CORE

## Research Component Core(s) (cont’d)

- Also:
- Indicate the performance site and key personnel, including the research component core director [use PHS Form 398 Form Page 2]
- Provide a listing in tabular format of the funded research projects that comprise the research base of each research component core

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Community Outreach and Information Dissemination

- Purpose:
- Integration of export centers into local communities
- Focus:
- Development and dissemination of culturally sensitive health information
- Encouraging/equipping for involvement in clinical studies and for participating in (or conducting) prevention and intervention activities
- Science education outreach activities

- 15-PAGE LIMIT

## Community Outreach and Information Dissemination

- Provide the following:
- Performance site(s) and proposed core director
- Overview of areas(s) of emphasis
- Target audience and participants
- Discussion of specific aims and objectives
- Discussion of relationships and lines of authority at partnering institutions
- Any committee structure and qualifications for committee

## Community Outreach and Information Dissemination

- Provide the following:
- Staffing plans and rationale for organization of component
- Methods, techniques and technologies to be used
- Issues of cultural sensitivity, if any
- Indication of how this component will assist in integrating center into the community

- IDENTICAL IN COMPLEMENTARY APPLICATIONS

## Pilot Project/Feasibility Study Core

- Purpose:
- Provide modest research support (up to two years) to enable eligible investigators to explore the feasibility of a concept related to the Center’s goal
- Focus:
- Initial support for new investigators
- Exploration of innovative new leads or new directions
- Stimulate investigators from other areas to lend expertise to minority health/health disparity

## Pilot Project/Feasibility Study Core

- Part 1 – Administrative Issues
- Describe/discuss:
- Objectives, functions, organizational infrastructure, including lines of authority
- Administrative procedures
- Any committee structure and qualifications for membership
- Proposed resources of core
- Activities designed to facilitate development/ completion of pilot/feasibility studies

- 15-PAGE LIMIT

## Pilot Project/Feasibility Study Core

- Part 2 -  Proposed Pilot Project/Feasibility Study
- Each pilot/feasibility study proposed should:
- Be on a topic related to the objectives of an area of emphasis for the Center
- Present a testable hypotheses
- Clearly delineate the question being asked
- Detail procedures to be followed
- Discuss how the data will be analyzed

## Pilot Project/feasibility Study Core

- Part 2 -  Proposed Pilot Project/Feasibility Study
- Provide for each pilot/feasibility study proposed:
- An abstract and listing of key personnel and performance site (form Page 2)
- Detailed budget
- Justification of eligibility of PI
- Justification of study as a pilot study, including how it fits into the Center’s area of inquiry
- Scientific proposal as outlined in PHS 398 (including justification for core use if applicable) 5-pages maximum

## Pilot Project/feasibility Study Core

- Part 2 -  proposed pilot project/feasibility study
- Provide for each pilot/feasibility study proposed:
- Information regarding human subjects or vertebrate animals, if applicable
- Literature cited

## Mentoring Core (R24)

- Describe/discuss:
- Objectives, functions, organizational infrastructure, administrative procedures
- Key personnel, including the core director
- Resources of the mentoring component within context of the program
- Detailed description of core activities, resources, research opportunities designed to assist junior faculty in enhancing research skills and career trajectory

- 15-PAGE MAXIMUM

## Mentoring (R24) 

- Mentoring core (cont’d)
- Mentoring and training activities may include:
- Didactics
- Opportunities to train in research laboratories
- Other activities designed to enhance competitiveness

## Training (P20 and P60)

- Undergraduates and graduates – activities:
- Didactics
- Opportunities to train in research laboratories
- Other activities to enhance competitiveness

## Training (P20 and P60)

- Describe/discuss:
- Objectives, functions, and administrative procedures
- Organizational infrastructure,including lines of authority at both partnering institutions
- Any committee structures and membership
- Key personnel, including the core director
- Resources of the training component within the context of the Center

- 15-PAGE MAXIMUM

## Training (P20 and P60)

- Training (cont’d)
- Also discuss/describe:
- Core activities, resources and research opportunities designed to assist junior faculty in enhancing research skills and research career trajectories

**TRAINING CORE: IDENTICAL IN COMPLEMENTARY ACTIVITIES**

## Health Disparities Education Core

- PURPOSE:	To augment existing or create new curricula among partners to apprise and culturally sensitize undergraduates, graduate students, post doctoral trainees in research, medicine, or public health of the need to reduce and eliminate disparities in health status

## Health Disparities Education Core

- Describe/discuss:
- Objectives, functions, administrative procedures
- Organizational infrastructure, including lines of authority at both partnering institutions
- Key personnel, including core director
- Any committee structure and membership
- Proposed core activities
- Resources available to core

**15-PAGE MAXIMUM**

## The Application Process

- The application process has two steps:
- Step 1.  Complete the application packet
- Step 2.  Deliver the application packet
***Watch out for that first step, it’s a doozy!***

## References and Letters of Support

- References
- Follow instructions in PHS 398
- List all references - include title, all authors, book or journal, volume number, page numbers, and year of publication
- Limit list to relevant and current literature
- Letters of Support
- Provide letters of support for the Applicant Institution, only

## Consortium/Contractual Arrangements

- Follow instructions in PHS 398
- Explain the programmatic, fiscal, and administrative arrangements to be made between the applicant organization and the consortium organization(s)
- Obtain signature of authorized organizational official on the Face Page to signify understanding of NIH consortium agreement policy

## Checklist

- Use Checklist Form Page in PHS 398, for Applicant Institution, only
- Identify type of application, check all that apply
- Include program income, if anticipated
- Obtain official signature for Assurances/Certifications
- Include established Facilities and Administrative (F&A) cost rates
- Identify whether environment is smoke-free (no impact on funding)

## Appendix Material

- Follow instructions in PHS 398, for Applicant Institution, only
- Include five collated sets (3 to CSR, 2 to NCMHD)
- No page numbering necessary
- Identify each item with the name of the Principal Investigator

## Personal Data on Principal Investigator/Program Director

- Use Personal Data Form Page in PHS 398
- Place this form at the end of the signed original copy of application
- Do not duplicate

## Confidentiality of Information

- Proprietary information (trade secrets, privileged or confidential information) should be included ONLY if it is deemed essential to the application
- Any pages containing confidential information should be identified according to the PHS 398 instructions
*Proprietary information is furnished to the Government in confidence with the understanding that the information will be used and disclosed only for evaluation of the application*

## Delivery Logistics

- Center for Scientific Review
- National Institutes of Health
- 6701 Rockledge Drive, Room 1040,
- MSC 7710
- Bethesda, MD  20892-7710
- Bethesda, MD  20817 (for express/courier service)

- Submit two additional copies of the application to:
- Dr. Jean L. Flagg-Newton
- Deputy Director, National Center on Minority Health and Health Disparities
- 6707 Democracy Blvd., Suite 800,
- MSC 5465
- Bethesda, MD  20892-5465
- Phone: 301-402-1366   Fax: 301-480-4049
- E-mail: Flaggnej@ncmhd.nih.gov

- Total number of applications to CSR plus NCMHD cannot exceed six

**Delivery Logistics**

## Application Receipt

- CSR and NCMHD document receipt of packet
- Date and time of receipt are stamped on packet
- If received after specified date and time:
- May be accepted if legible proof-of-mailing date no later than one week prior to deadline date
- Will be accepted if waiver request included, AND waiver approved after review
- Applications with receipt confirmations are submitted for review