# Presentation: 920769

## Prevention Research Centers

**Prevention Research Centers**
**Funding Opportunity Announcement**
**Category 1**

**August 12, 2008**

## General Information

- Conference call is being recorded
- We will provide specific information and allow time after each section for questions and answers
- PRC FOA Information website: _[http://www.cdc.gov/prc/news/2008-foa-announcement.htm](http://www.cdc.gov/prc/news/2008-foa-announcement.htm)_
- We will reference the FOA throughout the session

## Agenda 

- Introductions
- Overview of PRC Program
- FOA DP09-001
- Category 1 Applications
- CDC Extramural Research Review Process
- PRC Application Review Process – Category 1
- Questions and Answers

## Introductions

- Jo Anne Grunbaum, Research and Evaluation Team Lead, Prevention Research Centers (PRC) Program office
- Brenda Colley-Gilbert, Director, Extramural Research Program Office (ERPO)

## Overview of PRC Program

## PRC Program History

-   1984:  Congress authorizes Prevention Research 			Centers (PRC) Program
-   1986: First 3 Centers funded
-   1993: 9 PRCs funded
- Special Interest Projects (SIPs) began
-   1998: 23 PRCs funded
-   2004: 33 PRCs funded

## PRC Program Core Funding1986–2007

- Year

## Special Interest Project Funding1993–2007

- Year

## PRC Mission

**	**
**	****T**he PRCs work as an interdependent **network** of community, academic, and public health **partners** to conduct **prevention research** and promote the wide use of practices proven to promote good health

## PRC Committees

- Steering Committee
- Research Committee
- Evaluation Committee
- Program Committee
- Communication and Dissemination Committee
- Policy Committee
- National Community Committee**	**

## 
FOA DP09-001
Health Promotion and Disease Prevention Research Centers

**FOA DP09-001**
**Health Promotion and Disease Prevention Research Centers**

## Intent of the FOA

- This FOA will support a network of PRCs that:
- Focuses on major causes of disease and disability with an emphasis on underserved and minority populations
- Improves public health practice through community-based participatory research (CBPR) process
- Designs, tests, disseminates, or translates effective public health programs at state and community levels
-  **	**

## Timeline

- Letter of Intent receipt date:	September 8, 2008
- Application submission date:	October 8, 2008
- Peer review date:			December 2008
- Council review date:		January 2009
- Anticipated start date:		September 30, 2009

## Eligibility

- Schools of public health accredited by the Council on Education in Public Health (CEPH)
- Accredited schools of osteopathy and accredited schools of medicine that offer an accredited Preventive Medicine Residency program, or are in the process of obtaining accreditation for a preventive medicine residency program
- NOTE:  An institution may submit, or be part of, only a 	  single application
**	**

## Eligibility (cont.)

- Have a multidisciplinary faculty with expertise in public health and a working relationships with relevant groups (e.g.,  medicine, psychology, nursing, social work, education, and business)
- Have graduate training programs relevant to disease prevention
- Have core faculty in epidemiology, biostatistics, social sciences, behavioral and environmental health sciences, and health administration
- Have demonstrated curriculum in disease prevention
- Have capability for residency training in public health or preventive medicine
- Meet other such qualifications as the Secretary [of HHS] may prescribe

## 2009 FOA: Categories of Support

- Two categories of support:
- Category 1:  Comprehensive organizational infrastructure, strong community relationships, and plans in place with their community partners to conduct a core project using CBPR
- Category 2:  Need to develop infrastructure or community relationships in order to develop and implement a core pilot study using CBPR

## Category 1

- Comprehensive organizational infrastructure and leadership model
- Experience supporting multidisciplinary prevention research
- Defined partner community
- Experience in CBPR activities including communication and dissemination, training, and evaluation
- Able to implement innovative, high-quality prevention research

## Category 2

- Environment and available resources to support development of a comprehensive center capable of leading CBPR and related endeavors
- Capacity to support long-range planning and implement PRC key activities in community engagement and partnerships, communication and dissemination, training, and evaluation
- Institutional commitment to the PRC Program

## Budget

- 5 years of support
- $25,000,000 in fiscal year 2009
- Up to 33 PRCs funded
- Category 1:**	**$700,000 - $1,000,000 (total costs) per year
- Category 2:	$300,000 - $500,000 (total costs) per year
- 			Up to three may be funded
-    Applications that submit a first year budget greater than the ceiling of the category for which they are applying will be considered non-responsive and will not be reviewed.

## 
QUESTIONS

**QUESTIONS**

## 
Category 1
Applications

**Category 1**
**Applications**

## Application

- A complete application will contain **two separate proposals** prepared using the PHS 398:**	**
- 1.   Center proposal
- 2.   Core research project proposal
- Each proposal is reviewed and scored separately
- Paper submission only – original and three signed copies of each proposal

## PHS 398 Content of Research Plan

- 2. Specific Aims
- 3. Background and Significance
- 4. Preliminary Studies/Progress Report
- 5. Research Design and Methods

## Center Proposal

- Composite 12-month budget and justification for center and core research project
- PD/PI for overall center and key personnel
- 25 page limit for items 2-5 of Research Plan
- Key elements – infrastructure and administration, community engagement and partnerships, communication and dissemination, training, evaluation
- Applicants funded under PA04-003 must include a progress report highlighting PRC achievements from current funding cycle

## Core Research Project Proposal

- 12-month budget and justification for research project
- PD/PI and key personnel for core research activities
- 20 page limit for items 2-5 of Research Plan
- Research plan – same level of detail required for traditional research grant applications
- Applicants funded under PA 04-003 must provide evidence of successful and timely implementation of a CBPR project within the past five years

## Appendix Instructions

- One appendix for each proposal – Center and Core Research
- Five CDs for each proposal
- PDF format when possible
- Label each disk with the PD/PI name and application title
- For MAC, select ISO 9660 format
- Do not use compression, passwords, encryption, digital signature or certification

## Appendix Materials

- Up to 3 publications
- Accepted not published
- Published if online link not available
- Patents
- Surveys, questionnaires, data collection instruments, clinical protocols, consent documents
- Publicly accessible documents include URL or PMC ID number with full citation

##    Category 1:  Center ProposalInfrastructure and Administration 

- Organizational chart
- Description of PRC’s mission, goals, and health priorities and disparities
- Evidence of institutional commitment
- Qualifications of PRC director
- Staffing plan
- Multidisciplinary faculty; experience partnering with the community
- Faculty and staff experience
- Evidence of on-going prevention projects and activities
- Evidence of funds to support travel to Directors’ meeting

##      Category 1:  Center ProposalCommunity Engagement and Partnerships

- Expertise engaging in CBPR
- Defined partner community
- Existing community committee
- Community support for center and proposed research project
- Plans to obtain community input
- Engagement with appropriate partners
- Identification of NCC representative and funds to support travel

##    Category 1:  Center ProposalCommunication and Dissemination

- Infrastructure of resources and personnel
- Ability to develop and maintain a PRC website
- Focused and realistic center-wide communication plan
- Capacity and experience developing and disseminating materials to stakeholders
- Experience communicating activities related to research projects

##     Category 1:  Center ProposalTraining

- Evidence of previous training, technical assistance, and mentoring of:
- Community partners involved in core research project
- Partners, practitioners, researchers, and students
- Training plan that reflects the mission of the PRC
- Description of how training is integral to CBPR and capacity building of the community and other partners

##   Category 1:  Center ProposalEvaluation

- Logic model based on national logic model tailored to the PRC
- Realistic and focused evaluation plan aligned with the logic model
- Ability to engage stakeholders in evaluation activities
- Infrastructure to support evaluation and monitoring activities
- Description of how evaluation results are intended to be used

##     Other Submission RequirementsPRCs Funded Under PA04-003

- In Center Proposal report on accomplishments and achievements:
- Efficient and timely implementation and dissemination of prevention research
- Specific aims, progress, collaborations, innovative work, and important research findings
- Relevant publications and other products
- Served as local, state, or national resource

## 
QUESTIONS

**QUESTIONS**

##     Category 1 Core Research Project Proposal

- Core research project using CBPR
- Related to PRC mission and the community
- Evidence of successful and timely implementation of CBPR in past 5 years

##  Category 1:  Core Research ProjectInformation

- Specific aims, relationship of research project to center’s mission and health priorities and needs of the research community
- Background and significance with evidence of community and partner support
- Evidence of partner and community input into identification of health priorities and how they will be engaged throughout research process

## Category 1:  Core Research Project Information (cont.)

- Project team’s experience conducting research with the community and in the research topic and methods
- Study participants
- Power calculations
- Implementation timeline
- Report and dissemination plans

## Category 1:  Core Research ProjectGuidelines

- Determinant
- Intervention*+
- Dissemination*
- *   Identify or modify an existing evidence-based intervention to new population or setting
- *   Identify or modify an existing practice-based intervention to a different setting
- +  New intervention must provide rationale and demonstrate no applicable intervention exists

##     Other Submission RequirementsPRCs Funded Under PA04-003

- 	In core research project proposal report on how center successfully conducted a CBPR project in a timely manner that
- Provided new knowledge
- Impacted the field of prevention research for an underserved community

## 
Questions

**Questions**

## CDC Extramural Research Review Process

## Two-Level Review Process for Extramural  Research Applications

- Initial Merit Review (External)
-   Panels of external subject matter experts
-    (Special Emphasis Panel [SEP])
-   Scientific and Technical Evaluation
-   Priority Score/Ranked List
- Secondary Review (Internal)
- Panel of senior federal officials
-        (Secondary Review Committee)
- Programmatic priority/relevance
- Agency and Center goals and priorities	**	****	**

##  Special Emphasis Panel

- A consistent process that is:
- Guided by extensive federal requirements
- Addresses real and potential conflicts of interest
- Fair, objective, transparent
- Recognized by the extramural research community
- Provides valuable feedback to the applicant
**	****	****	**

## Selection and Appointment of SEP Reviewers

- Extensive federal government requirements for SEP
- Balanced membership of minority, gender, and geographic representation
- Appointed by CDC Director
- Members serve for a single SEP

## Results of the SEP

- Each application is discussed and scored
- Research Review Criteria:  Significance, Approach, Innovation, Investigators, Environment
- Each applicant receives a Summary Statement:
- Priority Score
- Reviewer Critiques
- Panel Roster
- Ranked list of applications by priority score** **

## Secondary Review Committee

- Internal federal officials
- Reviews results from SEP and program recommendations
- Makes recommendations for funding based on scientific merit, program recommendations, funding preferences, and alignment with Agency and Center goals and priorities

## Review Processfor Category 1 Applications

- Initial merit review (SEP)
- Two separate panels will be convened:
- Center Proposal
- Core Research Proposal
- Application numerical score will reflect the evaluation of the center proposal and the core research proposal
- Secondary review
- Results of initial merit review from both panels
- Program recommendations
- Make recommendations for funding based on scientific merit, program recommendations, funding preferences, and alignment with Agency and Center goals and priorities

## Category 1:  Center Proposal Review Criteria

-  Significance
-  Approach
-  Innovation
-  Investigators
-  Environment
-  Community Engagement and Partnerships
-  Communication and Dissemination
-  Training, Technical Assistance, and Mentoring
-  Evaluation

## Category 1:  Core Research Project ProposalReview Criteria

-  Significance
-  Approach
-  Innovation
-  Investigators
-  Environment

## Category 1:  Applicants Funded under PA04-003

- Center Proposal
- Develop and maintain community and partner engagement
- National, state, and local resource in prevention research, CBPR, working with a specific community
- Core Research Project Proposal
- Successfully conducted a CBPR project in a timely manner

## 
Questions and Answers

**Questions and Answers**