BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 337913

## Take Home Messages--Aromatase

- Consider a 2-stage assay
- 1st stage to answer whether chemical is an inhibitor
- 2nd stage to develop quantitative measure
- Investigate changing the experimental design to calculate Ki and km rather than IC50 since they are independent of substrate concentration.
- Ask pharmaceutical companies to sell us aromatase inhibitors that will not be commercialized.
- Ask GeneTest about their studies comparing plancental assays and their recombinant assay system.

## Take Home Messages--Steroidogenesis

- More thought needs to be given to chemical selection.
- Find chemicals with only a single, well defined mode of action
- Consider use of a Ca++ channel blocker as a steroidogenesis inhibitor
- Fenarimol may inhibit all P450
- Revisit the cell toxicity issue
- Should focus on Leydig cells.
- Leydig cell toxicity may be a relatively slow event compared with enzyme inhibition

## Steroidogenesis (cont)

- Dose selection should be carefully considered.  Discuss at August meeting.
- Check the ECVAM website for guidance on dose verification and analytical chemistry.
- E-mail questions.
# Presentation: 158484

## D0 Weekly Summary: May 11th to May 18th 

- Delivered Luminosity and operating efficiency
- Delivered 8.5pb-1
- Recorded 7.8pb-1 (92%)
- Very smooth data taking. Inefficiency down to 8% this week from 14% last week
- HV down closer to the end of store
- Less frequent change of runs.
- FEBs reduced
**Less L2 monitoring, fewer noisy silicon channels**
- Performance of the Tevatron was very stable
- Total number of events collected
- 13 million.
- Beam halo
- Mainly close to be within specs
- Beam position
- Within 1mm from the detector center and stable

**Day of the week **

- Nirmalya Parua

## Accesses

- D0 had requested 2 accesses over the past week
- 20 minutes long access on Saturday was used to improve the grounding of the FPD detector. Earlier grounding could have adverse effect on the calorimeter noise performance
- An hour long access on  Sunday was used to replace a failed power supply in the Forward Muon system. 25% of the C-layer forward muon system was affected due to this failure that occurred on Saturday.
- Right now no access is requested from D0.

- Nirmalya Parua

## D0 Summary

- Stably collecting physics data with full detector in readout
- 92% weekly data taking efficiency
- Stably above 85% during month of May
- Clearly see improvements in Tevatron luminosity lately
- 4 of the 10 best Run II days in terms of recorded luminosity are last week
- 5 of the 5 best Run II stores in terms of highest initial luminosity are from last week
- Plan for this week
- Physics data taking during stack and store operations
- No access requests

- Nirmalya Parua

## Status of the Calorimeter

**Calorimeter is performing well and stably.**
**L1 calorimeter trigger is fully commissioned and being readout **
**Trigger coverage is improved from |********|<2.4 before January Shutdown to |********|<3.2 since March 2003.**

**>99% channels**

- Nirmalya Parua

## Status of the calorimeter

**Only few non working channels ~40 (<0.1%) scattered across the detector.**

- Nirmalya Parua
# Presentation: 202733

## RHIC Machine/Detector Planning Meeting 17 November 2004

_**Agenda**_
**Schedule Issues (Montag)**
**General Remarks (Pile)**
**Report from Accelerators (Pilat)**
**The plan to get to Cu-Cu physics operation**
**Other**
**Polarized Proton Update (Bai)**
**Report from experiments (STAR,PHOBOS,PHENIX,BRAHMS)**
**Work left to be done in preparation for Cu-Cu physics run**
**When do 24 hr shifts begin**
**Physics goals for Cu-Cu run**
**Required run conditions to achieve goals – luminosity, ********* etc. **
**Special requests**
**RCF Issues (Throwe)**
**Other business**

## RHIC Machine/Detector Planning Meeting 17 November 2004

_**Purpose of this meeting:**_
- To address issues and priorities relating to the optimization of physics output from RHIC experiments.
- To discuss and promulgate policy (when needed).

## RHIC Machine/Detector Planning Meeting 17 November 2004

_**PAC Recommendations (very short summary):**_
- 8-10 week pp run should have highest priority
- Cu-Cu run should accumulate an integrated delivered luminosity of at least 7 nb-1 at        = 200 GeV
- Cu-Cu at         = 62.4 GeV and 1 day at injection is advisable if above goals are met
- 1-2 day pp (unpolarized) run at        = 400-500 GeV desirable

## RHIC Machine/Detector Planning Meeting as of 16  Nov 2004

**Overall Plan **(based on presidential budget)
**18 Nov 04 - Cryo on**
**19 May 04 – RHIC Run 4 ends**
**26 May 04 – RHIC cryo switched to LN****2 ****(27 weeks total)**
**Details – as run/planned**** *****(some details based on ’04 run and are subject to change)***
**18 Nov 04 – Cool down begins**
**25 Nov 04 – Blue Ring Cold**
**2 Dec 04 – Yellow Cold**
**3 Dec 04 - “2 week” RHIC setup with beam begins**
***16 Dec 04 – “2 week” ramp-up with colliding beams begins***
**Late evening stores for experiments**
**2, 8 hr accesses for experiments if needed (based on last year’s plan) **
***30 Dec 04 – 8 week physics with 100 GeV/n x 100 GeV/n Cu-Cu begins***
**12 Jan 05 - First experiment access, bi-weekly thereafter (all up to 8 hrs and only if needed)**
**5 Jan 05 - First beam experiment, weekly thereafter (up to 12 hrs/week)**
**24 Feb 05 – Nominal end of 8 week Cu-Cu run**
***24 Feb 05 – begin 3 week pp setup***
***17 Mar 05 – Begin 9 week pp Physics run***
**19 May 05 – end 9 week pp run, RHIC Run 5 ends**
**26 May 04 – Cryo switch to LN****2**** complete, 27 weeks of RHIC cryo operation ends**

## RHIC Machine/Detector Planning Meeting

**End of Run?**

**Minimum Goal**

## CRYO

**CRYO**

**AGS**

**RHIC**

**as of 16 Nov 04**

**BNL Base**
# Presentation: 106485

## Restricted Data in the Social Sciences

**Restricted Data in the Social Sciences**

- Prepared for the Breakout session on Privacy Issues vs. Public Access, NDIIPP,
- July 9, 2008

## Evolution of Social Science Data

- Since the 1960’s ICPSR has been disseminating public-use, quantitative  data files

## Evolution of Social Science Data

- Long-term investigations – many data points for a given individual
- Data about places, contexts
- Commercial data accessible for merging

## Evolution of Social Science Data

- Increasing pressure to balance access to data with protection of confidentiality
- Large public investment in social science data

## Evolution of Social Science Data

- Around 2000, ICPSR developed restricted data dissemination procedures
- Not long after ICPSR’s Data Enclave was established

## Examples of Sensitive Data

- Exploring Women's Histories of Survival of Violence and Victimization in a Midwestern State, 2004-2005
- Sensitive Topic
- Narrow Geography
- Qualitative information
- Michigan Student Study, 1990-1994
- Known timeframe
- Narrow sampling frame
- Detailed demographic and educational data

## Disclosure Analysis

- Attributes that can be known by an outsider (age)
- Usually not attitudes or beliefs
- Availability of geographic data.
- The more specific the geography, the more attention must be paid to disclosure risk.

## Two Types of Disclosure Risk

- Type I disclosure: when an intruder has knowledge that a given person (or organization) is included in a survey and the intruder attempts to find this record.
- Type II disclosure: when an intruder does not know the identity ahead of time and uses externally available resources (linking databases) to attempt to find survey respondents.

## Common Methods of Reducing Disclosure Risk

- Release a sample (of a larger data collection)
- “Collapse” data categories (e.g., combine categories, top- and bottom-coding, converting continuous variables to categories)

## Methods of Reducing Disclosure Risk

- Suppress data that illuminate unique cases (e.g., blanking variables with sensitive information or removing unique cases altogether)
- Perturb values of the data (e.g., adding random noise or distortion, microaggregating, swapping cases, suppressing, and re-imputing data)

## Restricting Access

- Restricted-Use Data
- Restricted-use agreement
- Application, Bonafied researcher with a research plan, IRB approval, Data security plan, Data mailed, User’s institution legally bound in the agreement, Data destroyed after agreed upon time
- Secure Data Enclave
- On-site analysis at ICPSR, non-networked computing environment, monitored, output reviewed

## Data-PASS Results

- Data-PASS has dealt with primarily public-use data
- ICPSR has uncovered through LEADS a non-trivial number of “at risk” studies that have disclosure risk problems (e.g. audio clips, video clips, qualitative interviews)
- Out of scope for Data-PASS, but ICPSR will pursue many of these collections outside of Data-PASS.

## Thank you!	

- For more information:
- www.icpsr.umich.edu
- Amy Pienta
- apienta@umich.edu
# Presentation: 002417

## Estimating electricity use “associated with the internet”:  A cautionary tale

- Jonathan Koomey, Ph.D.
- Lawrence Berkeley National Laboratory
- JGKoomey@lbl.gov, 510/486-5974, http://enduse.lbl.gov/
- Talk is on the web at http://enduse.lbl.gov/shareddata/telecomtalk.ppt
- Presented at the Telecommunications Industry Energy Workshop
- AT&T Technology Center, Washington DC
- March 20, 2000

## Background

- _x0008__x0008__x0008__x0008_“The Internet Begins with Coal”, by Mark Mills, was published in *Forbes* in May 1999.
- Overall results were widely cited.
- Memo to EPA dated 9 December 1999 was our response.
- Congressional testimony given by Mills and Joe Romm on 2 February 2000.

## Mills’ analysis was fatally flawed

- Bad data: 1-2 kW PCs, 500 kW central offices, 250 kW mainframes, confusion of web sites and servers.
- Bad boundary definitions: Just what part of a PC or a server is “associated with the internet”, anyway?
- Overlooked systemic effects: information tech. can affect the efficiency of many processes.

## Mills’ electricity “used by the internet”, corrected by LBNL

**TWh per year**

## Conclusions

- Misinformation seems to spread more quickly than truth.
- Electricity used by computers and network equipment is at least a factor of eight smaller than Mills implies.
- Understanding the systemic effects of information technology is critically important.
- Credible data are urgently needed.
# Presentation: 518541

## COTS MEMS Technology Assessment(new for FY04)

** **

| Cost   |   | 55K/0.1 |
| --- | --- | --- |
| Schedule |   | 6 months |
| Technical |   |  |
| Programmatic |   | Immediate applications in code R wind tunnels |

**Total ROM Cost (non-CS) = $ 55K **

**Description:**

**Benefits:**

**Schedule/Costs:**

**Risks:**

- Red, Yellow, or Green

**Lead Center/PI: ****LaRC – 55K/0.1**

**CS FTEs =  0.1 **

**Deliverables:**

- Commercial Off-the-Shelf (COTS) Micro-Electromechanical (MEM)
- devices provide a smaller, cheaper alternative to conventional sensors.
- Reduced package mass and volume allows sensor arrays to be
- embedded more densely and in tighter locations.  “Cheaper” not only
- means a lower implementation cost, but entire sensor solutions could
- be classified “throwaway”. This study compares and contrasts
- MEMS technical solutions with their conventional counterparts. Wind
- tunnel testing using MEMS accelerometers and gyroscopes will be
- discussed. Benefits and determents of cost, size, bandwidth, and science
- accuracy of several COTS MEMS sensor types will be explored.

- COTS MEMS solutions seem ideal for a wide range of technical
- issues, but drawbacks seem to include fabrication costs, power requirements, and size of supporting PCBs.  This study will aid in the development of cheap, tiny sensors for flight experiments, wind tunnel measurements, etc. and acts as a basis for future COTS MEMS research.

- Survey of available MEMS technologies and their non-MEMS counterparts
- Survey of technical evaluation of MEMS devices and their non-MEMS counterparts
# Presentation: 066106

## Membership Component

- Process Workflow Model

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## Membership Component

- Object and State Models

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# Presentation: 021238

## Ground Based Inerting Proof of

- Concept Flight Test in Conjunction
- with the Boeing Company

## Outline

- Background
- System
- Status

## Background

- Focus of the testing is to determine if the Existing Fleet Vented Fuel Tanks Will Maintain NEA Benefit for a Significant Amount of Time
- Boeing Offered Use a Boeing B-737NG as the Test Aircraft
- Air Liquide Provided a NEA Generator with Delivery Regulator at Low Cost
- Boeing to Provide Aircraft NEA Manifold, Support Personnel, Data Acquisition, and Some Instrumentation.
- Tech Center to Provide Oxygen Analysis Equipment

## Oxygen Analysis System

- System to Provide 8 Channels of Continuous Oxygen Concentration Data at 8 Different Fuel Tank Locations
- Actively Controls Sample Inlet and Outlet Pressure.
- Flow Through Sensor Design
- Fluid Traps, Ejector/Evacuator, Flame Suppressors for Safety
- Safety Analysis Must Be Completed and Accepted at the Readiness Review
- FMECA Done
- Fault Tree Failure Mode Analysis Done
- Failure Rate Data Still Incomplete

## System Block Diagram

## OBOAS Photo

## Status

- Aircraft Identified as B-737-900 Approximate Date of Aircraft Modification Start 2/1/2001
- OBOAS Has Been Shipped to Boeing Field
- System to Undergo EMI Testing on December 18th 2000
- Safety Analysis Must Be Completed and Accepted at the Readiness Review Date TBD
- Approximate Start of Testing Date 2/15/2001
# Presentation: 534164

##   Cocaine- and Extinction-Induced

**Neuroplasticity in AMPA Receptors Regulate**
**Drug-Seeking Behavior **

**DAVID W. SELF, PH.D.**
**Associate Professor of Psychiatry and Neuroscience**
**The Seay Center for Basic and Applied**
**Research in Psychiatric Illness**
**Southwestern Medical Center**

## Drug-Induced Neuroplasticity in the Mesolimbic Dopamine System

**DA**

**VTA**

**White et al., 1995**
**Zhang et al., 1997**
**Ungless et al., 2001**
**Saal  et al., 2003**

**Notes:**
Our work suggests that this bi-directional regulation of synaptic plastciticy in  the VTA and NAc both contribute to enhanced cocaine seeking and a propensity for relapse.

## Herpes Simplex (HSV) Viral Vectorfor In Vivo GluR1 Over-Expression

**HSV-lacZ**
**HSV-GluR1 WT **
**HSV-GluR1 S845A**
**HSV-GluR1 S831A**
**HSV-GluR1 Q582E**
**HSV-GluR2 WT **

- Adapted from Bredt and Nicoll, 2003

**Notes:**
Studies conducted by Malinow and others indicate that over-expression of WT and dominant negative  GluR constructs alters AMPA-mediated synaptic responses both in vitro and and in vivo 

## NAc Glutamatergic Deficits in Cocaine Addiction

_**Input to NAc**_
**	**
**Hypofrontality in humans****	****	****(Volkow et al., 1992, 2000; ****	****	****London et al., 1999)**
**Reduced basal extracellular glutamate**** ****	****	****	****	****(Keys et al., 1998; Bell et al., 2000)**
**Reduced AMPA response**
**	****(White et al., 1995)**
**LTD in PfC-NAc synapses w/sensitization****	****	****	****(Thomas ****	****et al., 2001)**

**NAc Glutamatergic Deficits in Cocaine Addiction**

## mRNA Levels

**Sutton et al., 2003**

## Cocaine-Seeking Behavior

**Drug-paired lever responses**

**Sutton et al., 2003**

## HSV-GluR1/R2 reduces cocaine only

_**Cocaine**_

**Extinction**

**Sutton et al., 2003**

## Acknowledgements

_**VTA Studies**_
**Kwang-Ho Choi**
**Scott Edwards**

_**Collaborators**_
_**Southwestern Med. Ctr.**_
**Lisa Monteggia**
**Amelia Eisch**
_**Harvard University**_
**Rachael Neve**

**Supported by NIDA grants DA 10460, DA 08227, DA 13796,**
**and the Wesley Gilliland Professorship in Biomedical Research**

_**NAc Studies**_
**Ryan Bachtell**
**Kwang-Ho Choi**
**Mike Sutton**
**Eric Schmidt**
**Kim Whisler**
# Presentation: 773624

## Statement before the Food and Drug Administration Public Hearing on Direct-to-Consumer Advertising

- Judith A. CahillExecutive DirectorAcademy of Managed Care Pharmacy
- November 2, 2005

## Academy of Managed Care Pharmacy (AMCP)

- Professional society
- Individual pharmacists
- Apply managed care principles
- 4,800 members nationwide
- Servicing 200 million Americans

## AMCP on DTC Advertising

*Supports* advertising to educate about:
- Disease symptoms
- Alternative treatment options
*Discourages* advertising that promotes specific prescription drug products

## DTC Advertising Can Improve Health Status

- Increases awareness about disease symptoms
- Informs consumers about treatment options and diagnostic procedures
- Stimulates patient/physician dialogue
- Encourages healthier lifestyles

## Product Specific DTC Advertising  Does a Disservice If . . .

- Its aim is to induce name recognition and  increase market share
- It creates an unwarranted patient demand
- It is misleading
- Risks are not fully explained
- It is silent about alternative treatment options

## Growth of DTC SpendingPost August 1997

- 1996
- 2004

- $791 Million
- $3 Billion

## August 1997 Guidance

- Ability to identify product by name
- Shift from patient information to marketing
- FDA Remedies
- Regulatory letter requiring withdrawal or revision
- No mandatory pre-approval

## 2002 GAO Findings

- DTC advertising appears to increase drug spending and utilization
- DTC advertising is concentrated among a small number of drugs for chronic conditions and many of the same are also promoted to physicians

## 2002 GAO Report (Cont.)

- Some manufacturers have repeatedly disseminated misleading ads for the same drugs
- Manufacturers have failed to submit, or to submit in a timely manner, all newly disseminated ads to FDA for review

## Medication Risks

- DTC advertising does not have a direct causal effect on the safety of medications, *however*
- Unwarranted demand attributed to DTC advertising can put patients in risk situations

## AMCP Suggestions

- Give FDA more authority over DTC advertising
- Mandatory prior approval
- Fund the agency sufficiently to be able to enforce requirements
- Oversee content
- Focus on raising awareness of disease
- Explore treatment options
- Stimulate patient/provider dialogue
- Encourage healthier lifestyles
# Presentation: 531577

## ARM Aerosol IOP – May 2003

**CIRPAS Twin Otter**

**ARM Aerosol IOP – May 2003**

- Twin Otter data used in 10 (8 in press, 2 in revision) publications for AIOP JGR special issue.
- Beat Schmid (PI and Platform Scientist) contributed to 8 of these through his current ARM ST activity.

## Aerosol Lidar Validation Experiment (ALIVE)

- Micro Pulse Lidar

- Raman Lidar

**NASA Ames Airborne Tracking 14-channel**
**Sun photometer (AATS-14)**

**Cessna 206**

**Research Scanning Polarimeter (RSP)**
**Navigational and Meteorological **
**Parameters**

**DOE**
**Oklahoma, Sep 11-22, 2005**
**Lead Scientist: B. Schmid**

**Sky Research J-31**

## Purpose

- Validate Aerosol Extinction Profiles over ARM CRF in Oklahoma derived from ground-based Raman and Micropulse Lidars
- Validate Aerosol Extinction Profiles derived from ARM Cessna 206 in-situ aerosol plane (IAP)
- Derive aerosol optical properties by combining AATS-14 and RSP measurements.

## Status and Schedule

- J-31
- Various DOE and NASA Safety Reviews
- AATS-14: Currently being calibrated at Mauna Loa, HI.
- RSP: Successfully integrated and test flown Aug 8-10, Ashland, OR.
- Reintegration and test flight of entire payload Sep 8-10, Moffett Field CA.
- C206: Expected in Oklahoma end of August.
- Raman Lidar: Mods completed last week with one exception: Mirrors not up top spec – vendor is producing replacement mirror(s) to be sent to site on 9/7
- MPL: 2 systems will be deployed. New system has 300 m blind spot. Older system: double pulse problem being worked.

## Operations

**Flights centered on ARM CRF 36.60°N, 97.48°E. **
**Timeframe: Sep. 11 – 22, 2005**
**10 days on site **
**23 on-site research flight hours**
**10-15 short duration flights**
**Two types of flight patterns**
**VFR only, avoid sun obscured by cirrus clouds**

## Type 1: Regular ALIVE Flights

## 
J-31 will wait until Cessna starts its 15K’ leg then take off (~25 min lag)
Vertical separation is always more than 1500 ft
ATC radar flight following at all times
Continuos radio contact between 2 aircraft
J-31 will RTB immediately if radio contact is lost
3-4 such flights

- Type 2: Intercomparison Flights

- J-31 will wait until Cessna starts its 15K’ leg then take off (~25 min lag)
- Vertical separation is always more than 1500 ft
- ATC radar flight following at all times
- Continuos radio contact between 2 aircraft
- J-31 will RTB immediately if radio contact is lost
- 3-4 such flights

## SGP Cloud and Land Surface Interaction Campaign (CLASIC)

**Planned for Summer 2007, Proposal submitted July 14, 2005**

**Steering Committee:**
**Mark Miller (BNL), Greg McFarquhar (University of Illinois), Larry Berg (PNNL),**
**Qilong Min (SUNY Albany), Beat Schmid (BAER Inst.), Dave Turner (PNNL)**

**SGP Cloud and Land Surface Interaction Campaign (CLASIC)**

- Platform Scientist, suggested potential payload within budget constraints
# Presentation: 937611

## Protecting Personal Information at Fermilab

## Outline

- Why must we protect personal information?
- What is Protected Personally Identifiable Information (Protected PII)?
- What are your obligations?

## Why?

- Identity theft based on improper disclosure of personal information is a serious problem
- Several government agencies have been embarrassed by losses of large quantities of personal data
- Orders from White House --> DOE --> Office of Science mandate more careful treatment of personal information
- Fermilab deeply respects the privacy of employees and users

## What is Protected PII?

- At Fermilab, Protected PII is defined as an individual’s name in combination with one or more of the following items:
- social security number or foreign national ID number
- passport number or visa number
- driver’s license number
- personal credit card number
- bank account number
- date and place of birth (both together, not one by itself)
- mother’s maiden name
- security clearance information
- biometric information (fingerprints, retinal scan, DNA)
- criminal records
- detailed personal financial information (not merely salary history)
- detailed medical records
- detailed educational transcripts (not merely a list of degrees)

## Your Obligations

- You must not have any Protected PII on any of your computers
- You will need to sign a statement that you have inspected your computers and deleted any Protected PII you discovered
- “Your computer” means any computer that you are the sole user of, and any file space you have on shared systems or servers.  System administrators will NOT examine users’ files; this is the responsibility if each user.

## Examples of PII that must be deleted

- Resumes or transcripts containing social security numbers or other Protected PII
- Conference databases with credit card numbers or visa numbers
- Spreadsheets with credit card or passport numbers of division/section travelers
- Word documents of trip reports or foreign travel forms containing passport numbers or other Protected PII
- Note that it is OK to enter Protected PII into external databases (like FTMS for foreign travel) as long as no local copies of reports containing things like passport numbers are kept on your computer.

## For more information

- If you need to access any of the Protected PII maintained by the laboratory (for example, in HR or financial databases) you will need additional training about proper procedures
- If you think you have a business need for keeping PII (or have any other questions) contact your division/section privacy representative

## Division/Section Privacy Reps

- AD
- CD
- PPD
- TD

- BSS
- Directorate
- ES&H
- FESS
- FIN
- HR
# Presentation: 716298

## Community meeting

**4-1**

**Training of Trainers  **

**LUNCH**

- CPT presentations

- CPT presentations
- Phase Five overview

## Purpose: Implement and evaluate the plan, and refine as needed.

**4-2**

**Training of Trainers  **

- •  Implement selected programs, policies and practices.
- •  Evaluate the process and outcomes.
- •  Adjust the plan.
- Support: Community Plan Implementation Training; 	Technical Assistance as needed

## 4-3

**4-3**

**Training of Trainers  **

## Any questions?

- What’s next?
- Practice presentation assignments
- Evaluations

**4-4**

**Training of Trainers  **
# Presentation: 076289

## The Tropical Tape Recorders of Aura’s MLS

**The Tropical Tape Recorders of Aura’s MLS**

- The “Tape Recorder” is the name given to the slow upward movement of trace gases into the tropical stratosphere. The tape recorder in water vapor was discovered by Mote et  al. [1996] analyzing UARS data.  A CO2 tape recorder is seen in tropical balloon data [Andrews et al., 1999].  With the launch of EOS Aura’s Microwave Limb Sounder we can clearly see the H2O tape recorders well as tape recorders in CO [Schoeberl et al., 2006], HCN [Pumphery et al. 2006] and O3! Apparently all that is required for a tape recorder is a trace gas that varies in concentration with time near the tropical tropopause.  For CO, HCN, and ozone  seasonal variations in tropical biomass burning and convection provide such variation.  Because CO and ozone have strong photochemical sinks in the stratosphere, their tape recorder signals do not extend much above the tropopause.

- M. Schoeberl and B. Duncan
- NASA/GSFC
- L. Froidevaux, N. Livesey, W. Read
- MLS Team/ JPL
- H. Pumphrey
- U. of Edinburgh

- The water vapor tape recorder. Above about 35 km the signal is disrupted by stratospheric SAO winds.  Black lines separate the positive and negative anomalies. White lines are temperature contours.  The dry regions originate with colder temperature periods. [also see Read et al., 2004]

- tropopause

- The CO tape recorder.  The CO signal tilts with height starting a little below the tropopause.  CO in the boundary layer is lofted by convection and high values occur coincident with to tropical biomass burning. The signal fades as CO is chemically destroyed by OH.  The black lines are the water vapor. [Schoeberl et al., 2006]

- The HCN tape recorder.  HCN is also is produced by burning peat and forest fires. HCN is fairly inert in the stratosphere.  This tape recorder is more difficult to detect because the concentration of HCN is low. HCN seems to have a more impulsive source. [data from H. Pumphery - see his poster!]

- The ozone tape recorder.  Boundary layer ozone is lofted by convection like CO and HCN, but above 18 km the tape recorder signal is erased by stratospheric production and dynamics.  Seasonal variations of tropical upper troposphere ozone and CO are anti-correlatted as expected with convective sources [Folkins et al., 2006].

- tropopause

- tropopause

- tropopause

| Species | Range | Cause |
| --- | --- | --- |
| H2O | Up to 35 km | Seasonal variations in  TTL temperature |
| CO2 | Up to 30 km
(detected by balloons) | Seasonal variations in tropospheric CO2 due to growing season |
| CO | Up to 22 km | Seasonal variations in tropical biomass burning and convection |
| HCN | Up to 35 km  | Burning peat, forest fires? |
| O3 | Up to 18 km | Seasonal variation in convection |

- CO Tape Recorder

- HCN Tape Recorder

- 2005

- O3 Tape Recorder

- Relative Ranges of the Tape Recorders

- 2006

- 2005

- 2006

- 2005

- 2006

- 2005

- 2006

- H2O Tape Recorder

- 2006

- 2005

- tropopause
# Presentation: 228350

## Woodstove Replacement Programs

- Cooperative Partnerships to Reduce Impacts from RWC
- USEPA’s Air Innovations Conference
- Chicago, August 10 -12

## Why a Changeout Program?

- Old Woodstoves _don’t wear out_
- Although seasonal, RWC can be major localized source of Fine PM
- Woodsmoke also Air Toxics issue
- Woodstove Households burn most of the Firewood – Make most of the Woodsmoke
- Majority of woodstove owners not aware of clearer technology

## “Why” – continued

- EPA – Certified Woodstoves are emit less small particulates, 50 – 90 % less
- During the Changeout, some Woodburning families switch to gas or pellet heaters – with even lower emissions
- Programs can also inform media on RWC impacts, & on deposition issues

## One approach – “Great Stove Changeout”

- Woodstove Industry created and tested the program in 1990 – Tested in Southern Oregon
- Seattle was first major metro area Changeout
- Industry program asks only minimal assistance from Government –

## Key Components of                               Great Stove Changeout  

- Consumer receives a Discount – Usually 10-15% on new EPA stove, Pellet Stove, Gas Heater
- Consumer **must** turn in their old woodstove
- Woodstove Dealer commits to oversee the disposal of old stove
- Woodstove Dealers will also  remove old stoves during program for reduced fee
- Government principally assists in Promotion Press event, although occasionally adds incentive funds
- _Program is primarily an education program_
- Each Program is unique, reflecting partners and targets

## Why Bother?  - Does it work?

- Majority of woodstove owners have owned stoves since 1980’s – oblivious to other options – serious education challenge
- 1990-91 Crested Butte project validates the approach –
- RWC app 80% of PM-10 inventory
- 80+% of old stoves changed in one year
- Dramatic 60% reduction in Fine PM

## “Great Stove Changeout Programs – the short list

- 1991 Metropolitan Seattle
- 1992 Reno, Nevada
- 1991-93 Oregon
- 1992 Washington
- 1994 Metro Denver & Colorado
- 1998 Northern California
- 2000 Great lake Pilot Project
- 2001 Great Lakes Great Stove Changeout

## Clean Air Act Excellent Award -2001

- _[http://www.woodstovechangeout.org](http://www.woodstovechangeout.org/)_
- Bi-National, Multi-State Effort
- Kick-Off Press events in 3 States
- St. Paul, Lansing, Madison
- Feb 1 – April 30, 2001

## Slide 9

## Canadian Version is Burn it Smart

## SEPs and Settlements

- Mt Zirkel Wilderness Settlement
- Majority of Colorado’s portion of LP Wood products Settlement – Delta County Colorado
- Focused on Very Low Income
- Subsidies for all fuel, but skewed to gas
- Regional “subsidies” during Great Stove Changeouts in Wisconsin & Nor Calif.

## Future Plans

- Work with Government & NGO partners wherever appropriate
- Interested in another ‘whole town changeout’ opportunity
- HPBA - Contacts
- Arlington, Va. – 703.522.0086
- Ontario, Canada – 705.788.2221
- Sacramento, Ca – 916.536.2390
# Presentation: 426127

## Aarohi Vijh
Midwest Optelectronics LLC

Chandan Das and Xunming Deng
University of Toledo

**Aarohi Vijh**
**Midwest Optelectronics LLC**
**Chandan Das and Xunming Deng**
**University of Toledo**

- NREL a-Si Meeting
- San Francisco, April 17, 2006

## Objectives

*To obtain IV characteristics of individual component cells in tandem and triple junction solar cell stacks*
*To build instrumentation to automate this process*

## Procedure developed at UT

- Get Voc-Isc relationships for top and bottom cells
- Measure Iscs under illumination of interest
- Obtain Voc values from Voc-Isc relations
- Scan IV of tandem cell under illumination of interest with top and bottom cells limiting
- Subtract Voc of other cell (shift the IV curve) to the left

- (Tandem Cells)

## Obtaining Voc-Isc (Tandem)

- With a blue probe light ON, measure Voc
- Add a stronger red bias light, measure Isc
- Turn red bias off, step up blue probe, repeat
- Gives Voc-Isc for top cell

- Top Cell Voc-Isc

- Bottom Cell Voc-Isc

- (Tandem Cell)

## Obtaining Cell VOCs and IV curves

- Measure Iscs at given illumination, get corresponding VOCs
- Reduce red light slightly, measure top-cell limited IV, shift to the left by an amount equal to VOC (bot)

- (Top)

- (Bottom)

## Response of Tandem Cell

| VOC=0.952V
ISC=1.78A
 | VOC=0.940V
SC
 |
| --- | --- |
| VOC=0.354V
ISC=22.6nA
 | VOC=0.040V
ISC=-150pA |

**Blue ON             Blue OFF**

**Red ON**
**                ****Red OFF**

- Blue light: 400nm from monochromator
- Red light: 800nm longpass filtered incandescent light

- Different Cell, Expected Voc=1.4V, Voc(bot)=0.4V, Voc(top)=1.0V

## Response of Tandem Cell

| VOC=0.768V
ISC=262nA
 | VOC=0.660V
SCn
 |
| --- | --- |
| VOC=0.355V
ISC=23.5nA
 | VOC=0.010V
ISC=-170pA |

**Blue ON             Blue OFF**

**Red ON**
**                ****Red OFF**

- Blue light: 400nm from monochromator
- Red light: 940nm IR LED

- 800 nm/940 nm fluxes were comparable

## Test setup with LED optical bias

## Bottom Cell IV with New System

- Voc = 0.39 V
- Isc = 1.24A
- FF = 49.5%

- Isc=1.24A

- Voc=0.55V

## Top Cell IV

## Status

- Have applied UT method for component cell IV determination in tandem cells
- Have assembled a computerized system for applying biases and acquiring data
- Trying to improve the determination of Vocs in a tandem cell

## Plan

- Use filters with LEDs to eliminate any tails, or better, use lasers
- Move further into IR for bottom cell probe light to reduce top cell response
- Instead of a fixed bias light intensity, use one that tracks the expected Isc of the probed cell
- If Voc-Isc relationship is accurately obtained for one cell, use that information to correct the Voc estimate for the other cell(s)
- Test procedure for higher intensities
- Test procedure for triple-junction cells
# Presentation: 530812

## Global Observations of HCHO and CHOCHO from the Ozone Monitoring InstrumentStatus Update

- Global Observations of HCHO and CHOCHO from the Ozone Monitoring InstrumentStatus Update

- Thomas P. Kurosu
- Harvard-Smithsonian Center for Astrophysics
- Cambridge, MA
- Aura Validation Workshop
*Boulder, CO, September 2006*

## Status of Products

- Official OMI data product
- Provisionally released - public release in October 2006
- Current version: v0.9.50 (reprocessing is at ~1 July 2006)
- Older versions: ≤v0.9.46 should not be used since they are wrong by a factor of ~2-4 (hence reprocessing)
- CHO-CHO
-  Research product; still under development
-  Available for Aura Science/Validation Team Members only
-  Public availability not before public release of L1b data
-  Processing of 1 year of data currently in progress

## Status and Currently Known Issues

-  Monthly averages comparable to GOME (v0.9.50)
-  Individual granules improving, but still limited usefulness
-  Further quality assessment awaits more feedback from validation
-  Patches in averaged columns due to coarse AMF (4 ̊x 5 ̊)
-  AMF needs general update (GEOS-Chem from T.-M. Fu/D. Jacob, Harvard)
-  Still significant striping; may be reduced with ECS 3 L1b
- CHO-CHO
-  Fitting window needs to be finalized
-  Requires AMF that includes scattering weights
-  Stripes, of course; may be reduced with ECS 3 L1b

## HCHO August 2006 (regular columns)

- HCHO August 2006 (regular columns)

## HCHO August 2006 (destriped columns)

- HCHO August 2006 (destriped columns)

## HCHO August 2006 (column uncertainties)

- HCHO August 2006 (column uncertainties)

## HCHO March 2006 (destriped Columns)

- HCHO March 2006 (destriped Columns)

## CHO-CHO March 2006 (destriped columns)

- CHO-CHO March 2006 (destriped columns)

## CHO-CHO July 2006 (destriped columns)

- CHO-CHO July 2006 (destriped columns)
# Presentation: 739012

## Application of molecular marker technologies on cereal crops improvement

- Shiaoman Chao
- USDA-ARS, Fargo, ND

## Slide 2

## Exploitation of High Throughput Marker Systems

- SSRs
- SNPs - detection system
- _Fluorescent Polarization_ (FP), a single SNP assay system, suitable for genotyping a small number of SNPs on a large number of samples, such as MAS.
- _Illumina’s BeadArray_, a high throughput platform for 1,536-plex SNP GoldenGate assay, suitable for whole genome scan and association mapping studies
- DArT - Diversity Array Technology, an arrayed based marker system, developed by Andrzej Kilian at Canberra in Australia. (Cost: US$3,500/96 samples)

## Slide 4

## Genotyping Project Work Flow

## Sample Submission Protocol from Breeders

- 96-deep-well plates (2ml) are provided
- Add ~0.25 gm of silica gel (16-20  mesh) into each well
- Cut and insert one piece of 11/2’’ leaf fragment in each well, dry samples at room temp
- Seal plates and mail plates to Fargo
- Store plates at room temp

## High Throughput Genotyping Protocol

**High Throughput Genotyping Protocol**
** **Liquid handling is automated.
- Plant DNA extraction
- PCR reaction setup
- Gel electrophoresis
- Data analysis – allele calls is done using a software

## Current Projects on MAS - Sample Processing

- Approximate current capacity:
- DNA extraction - process 12 to 16 plates per day
- Generate 8,000 data points/week
- A maximum 30,000-data point project (or 8,000 samples genotyped with up to 4 markers) is expected to take ~2 months from sample submission to data delivery

## Current Marker-Assisted Breeding Projects - collaborative projects with breeders in the public sector through grants

- wheat and barley MAS projects for FHB resistance.
- Marker validation associated with FHB resistance derived from various sources in wheat.
- MAS projects from wheat CAP

## Cost per Genotype

_**SSR marker**_
- DNA extraction		$0.12
- PCR reactions		$0.06
- Gel electrophoresis	$0.12 (4-marker assay)					$0.50 (1-marker assay)
- Labor			$0.30
- Total cost		$0.60 for 4-marker assay
- 			$1.00 for single marker assay
_**SNP marker**_
- FP assay		$0.60
- Total cost		$1.10
- Illumina’s system	<$0.05 (consumables)

## Effectiveness and Cost Efficiency of MAS

- Improving marker technologies, developing diagnostic markers.
- Breeding strategies
- backcrossing vs. two-way or topcrossing
- selection strategies, allele enrichment vs. fixation, population size
- number of marker/trait to be screened

## Fargo Genotyping Lab Staff

- Lee Brady (Cat 3) - coordinate and perform MAS projects
- Jamie Rust (Technician) - perform research projects and assist MAS projects
- Term appointment (Technician) - SNP development using Illumina’s technology and assist MAS projects

## Acknowledgements

- Funding sources,
- USDA-ARS/US Wheat and Barley Scab Initiative
- USDA CSREES wheat and barley CAP funds
- USDA-ARS CRIS funds
# Presentation: 431517

## a semi-analytic expression determining the influence of pressure-gradient and average shear on ballooning stability is determined
this equation provides the marginal stability diagrams

Collaboration with C.C.Hegna
thanks also to N.Pomphrey, A.Ware, R.Torasso, N.Nakajima

- this equation provides the marginal stability diagrams
- Collaboration with C.C.Hegna
- thanks also to N.Pomphrey, A.Ware, R.Torasso, N.Nakajima

- Influence of pressure-gradient, shearon ballooning stability

## The ballooning equation takes the form...

- depends on s2

## The pressure-gradient & shear are varied

- zero-order change in
- gradients

- first-order change in
- pressure and transform

- two free parameters p, 

## the coordinates are varied to preserve MHD equilibrium

It is the only the local shear which is affected to zero-order

The perturbed ballooning equation takes the form

- It is the only the local shear which is affected to zero-order
- The perturbed ballooning equation takes the form

- The coordinate response & perturbed ballooning equation are determined

## Eigenvalue perturbation theory is applicable

## Theory determines . . . .if increasing pis stabilizing or destabilizing; if a second stable region is likely to exist

|  |  |  |
| --- | --- | --- |
|  |  |  |
|  |  |  |

## Quasi-poloidal (m3b15) configuration

- quasi-poloidal configuration studied by Ware et al. has strong second stable region
- solid curve is stability boundary determined by exactly re-solving ballooning equation on grid 200x200
- dotted curve from analytic expression – single eigenfunction calculation

## LHD has second stable region near core

- LHD
- solid line is exact calculation; that is, solving the perturbed eigenvalue equation exactly on a grid 200x200
- dotted curve from analytic expression; requires only one ballooning calculation.

## NCSX li383

- li383
- solid line is exact calculation; that is, solving the perturbed eigenvalue equation exactly on a grid 200x200
- dotted curve from analytic expression; requires only one ballooning calculation.

## Usefulness of profile-variation method is verified by equilibrium reconstruction

- A sequence of equilibria,
- with increasing pressure,
- is constructed.
- Though the geometry is changing,
- the marginal stability diagram
- is a good predictor of stability limits
- The equilibrium is indicated with
-  + if unstable
-   if stable
# Presentation: 030723

## MTAC # 104List CertificationStatus Update

**MTAC # 104****List Certification****Status Update**

- USPS Co-chairs: Charles Hunt, James Wilson
- Industry Co-chair: Chris Lien
- USPS Sponsors: Charles Bravo, Nick Barranca
- Industry Sponsors: Ernie Rojas, Joe Lubenow

- February 22, 2007

## Pillars of List Certification

- List Criteria
- Pre-mailing

- Validation
- During Mailing

- Dynamic Feedback
- Post-mailing

## List Certification Criteria

- Applies **proactive** steps to ensure that each address within the list represents the **best** and most **current** information regarding the recipient and the physical address elements.  The following products would be applied no less than every 95 days on a given address.
- Goes beyond CASS standards
- All required elements are present
- DPV return code of ‘Y’
- Updated using LACSLink data
- Updated using a USPS approved pre-mailing solution
- Address data was obtained directly from the end mail recipient

## Validation During Mailing

- Can the Intelligent Mail® Barcode provide a solution for identifying the address source?
- Certified Address List Identifier (CALI) mapping to the Business Entity Identifier (BEI)

## Post-mailing Update

- Provides a feedback system to notify certified list administrators of suspect UAA
- Uses SHA (secure hash algorithm) versions of the addresses
- Any certified list administrator can check their SHA values against the Corrective Action Required List (CARL) to determine if a suspect UAA is in their list prior to renting or leveraging the data

## List Administrator

- Publisher
- Direct Marketer

- Printer
- Mail Service Provider

- USPS
- (PARS and possiblyFSS)

- Escrowed
- SHA-1
- data

- NCSC
- Memphis

- (CARL)
- Escrowed
- SHA-1
- data

- Mailing
- database

- Corrective Action Required(LACSLink) 150AFE12

- 1AFEB232
- 21034B1E
- 150AFE12

- 150AFE12 = John Smith
- RR 1 Box 6300
- Mount Sidney VA  24467

## Next Steps

- Forming subgroups centered around the three pillars
- Certification criteria
- Validation
- Post-mailing Update
- Teleconference planned in March
- Specific date and time to be announced
- Current workgroup conclusion date set for June, 2007
# Presentation: 001016

## Proton Source 2/2/07

- Operational Issues
- Ion Source Notching Status: Moehs
- Booster Corrector Sign Conventions: Prebys + discussion

## General

- My only requirement:
- All corrector packages will be wired with the same polarity, and this is the polarity that the MTF will use
- Two possible conventions:
- “Generic” (a la Syphers and Edwards)
- For normal elements, at y=0, positive currents give positive coefficients for
- Skew elements rotated half a pole *counterclockwise* from normal elements (as seen from beam)
- Determined by beam behavior
- Traditionally by effect in horizontal plane

## Proposal

- A “positive” current for each elements will do the following:
- “Horizontal” dipole: bend beam outward
- “Vertical” dipole: bend beam up
- Normal quad: horizontally focusing (increase horizontal tune)
- Normal sextupole: positive horizontal chromaticity
- Follow traditional convention between normal and skew elements
- Rotate skew quadrupole 45 degrees counterclockwise
- Rotate skew sextupole 30 degrees counterclockwise

## Dipoles (beam view)

- Bend outward (+x)
- Same as now
- Same as generic

- Bend upward (+y)
- Opposite now
- Opposite generic

- “Horizontal” dipole

- “Vertical” dipole

- B

- B

## Quads

- By

- x

- Bx

- x

- Normal:

- Skew:

- Opposite “generic”
- Same as now
- Positive horizontal tune change
- Negative vertical tune change

## Sextupole

- Opposite “generic”
- Same as now (?)
- Positive horizontal chromaticity
- Negative vertical chromaticity

- By

- x

- Bx

- y

- Normal:

- Skew:
# Presentation: 210387

## Antiproton source startup reportBill Ashmanskas 2006-06-02

- DVM elog titles evolved from “sad, sad story” to “fun & games”
- Got reverse protons to Accumulator & Debuncher by Saturday
- Many little trim supply cable swaps, etc.
- Obie changed out D:IB contactor
- Repercussions of kicker 165  465 ramp card swaps
- Accumulator aperture work.  Running wave correctly identified several limiting apertures, e.g. tank 301 moved during leak fix
- Acceptances comparable to February, except Deb V, Acc Inj V
- Prototype tank backwards; got data Thurs; swap arrays Friday
- Aim to remove tank (regain full Deb V acceptance) on Monday
- Got 120 GeV beam to target, some secondaries to end of AP2, by Thursday night
# Presentation: 458162

## Database Data Exchange

**Jerry Nunn**
**West Gulf River Forecast Center****November 19, 2002**

## Program Overview

**Three Main Components:**
**Standardization Component (SNOOPY/UPDATEDB)**
**Transfer Component (WHFSTran)**
**Consistency Check Component (in production – dependent on CR project )**

## Database Standardization Package

**UPDATEDB**** – Batch scripts to update selected table entries ****(automatic)**
**SNOOPY**** - a GUI used to make changes ****(interactive)**
**Final design yet to be determined;**
**Input from every region during the development and testing phase;**
**National Headquarters also involved**
** ****Goal:  Build consensus and “nationalize” the code.**

## Database Transfer Program (WHFSTran)

**Preliminary version in almost every SR office with WHFS**
**Shell program**
**Runs twice weekly on cron**

## Database Transfer Program (WHFSTran - continued)

**Unloads database tables & schema**
**Transfers ****(tarred and compressed) ****files to central server**

## Consistency Check Program

**Under development**
**Most likely a “C” program **
**Designed to be run at RFC and backup WFO**

## Consistency Check Program (continued)

**Automatically downloads files ****(created by WHFSTran) ****from selected WFOs**
**Creates version of WFO database in INFORMIX at RFC ****(or backup WFO)**

## Consistency Check Program (continued)

**GUI-based program then checks each table**
**Looks for differences in databases**
**Changes approved by user**

## Consistency Check Program (continued)

**Discrepancies stored in new database tables**
**Known discrepancies can be skipped with next pass**
**Considerable user freedom to make changes ****(or not)**

## In Summary...

**Standardization and transfer functions almost complete**
**Consistency check function expected Spring 2003**
**More details from Patrick...**