# Presentation: 203064

## Improving Cancer Outcomes for African-Americans

- New Hanover Regional Medical Center
- Coastal Area Health Education Center
- University of North Carolina at Chapel Hill
- University of North Carolina at Wilmington
- Report given at the Program Steering Committee Meeting
- 22 June 2006, Toronto

## Yearly Patient Accruals and Total Enrollment

- Clinical Trials (through Apr 2006)

|  | 2003 | 2004 | 2005 | 2006 | total |
| --- | --- | --- | --- | --- | --- |
| # | 0 | 9 | 13 | 1 | 22 |
| #(%)
black |  | 2(22) | 4(31) | 0 | 6(26) |

## Yearly Patient Accruals and Total Enrollment

- Navigated Patients (through Apr 2006)

|  | 2003 | 2004 | 2005 | 2006 | total |
| --- | --- | --- | --- | --- | --- |
| # | 0 | 5 | 43 | 25 | 73 |
| #(%)
black |  | 4(80) | 33(77) | 14(56) | 51(70) |

## Yearly Patient Accruals and Total Enrollment

- Psychological Study (closed 2005)

|  | 2003 | 2004 | 2005 | 2006 | total |
| --- | --- | --- | --- | --- | --- |
| # | 0 | 89 | 171 | na | 260 |
| #(%)
black |  | 28 (31) | 93 (54) |  | 121 (47) |

## Status of Clinical Trials

- Head & Neck trial
- Hyperfractionated IMR with weekly concurrent Cisplatin
- First investigator-initiated clinical trial at NHRMC
- 17 patients enrolled (3 black)
- Good early outcomes
- Treatment efficacy
- Potentially less toxicity

## Additional Clinical Trials

- Small cell lung ca – Chemo plus chest radiotherapy
- Ca of anal canal – Chemo + radiotherapy
- Prostate Ca (RTOG 0232) – External beam plus brachytherapy versus brachytherapy alone (enrolled one black male in June)

## Additional Clinical Trials

- Non-small cell lung ca – Cranial irradiation vs observation
- Non-small cell lung ca – Selenium supplementation
- Pancreatic ca (NSABP)– Chemo + radiotherapy vs chemo
- DCIS (NSABP) – Anastrozole vs Tamoxifen

## Peer-reviewed Publications

- Manuscripts in preparation
- Maguire, Hamann, Menon
- Prostate cancer risk groups and treatment choices (ASTRO poster)
- Maguire
- Treatment planning using TELESYNERGY ® (ATA presentation)
- Hamann, Mathews, Johnson
- Effects of cancer on cultural and social beliefs and attitudes (ASTRO poster)

## Peer-reviewed Publications

- Manuscripts in preparation, cont’d
- Kotwall, Maguire, Dobson, Hamann
- Racial differences in rectal cancer outcomes
- Kotwall, Cyr
- Racial differences in frequency of breast conservation surgery and breast reconstruction in women with Stages 0,1,& 2 breast cancer

## Partnership Relations

- UNC-Chapel Hill
- visits to Chapel Hill by PI
- educational conferences
- patient consultations
- Second site for Head & Neck trial

## TELESYNERGY ® Use

- Educational conferences
- Treatment planning
- Meetings
- Two papers at ATA, May 2006
- Honaker, Maguire, Rosenman
- A Year & a half of TELESYNERGY® in southeastern NC
- Maguire
- TELESYNERGY®: Bridging academic and community radiology oncology treatment planning

## Patient Navigator Program

- Active recruitment of patients
- Heavy schedule of outreach events
- Partnered with Prostate Cancer Screening project
- Staffing
- 2 ftes
- 2 volunteers
- Products
- Video
- brochure

## Status of Psychological Research

- Conducted 260 interviews
- Analyzed 228  interviews
- Interventions based on results
- Web-based curriculum modules for MDs
- Clergy Day on Cancer
- Pending proposal
- Increasing the Utilization and Impact of the NCI’s Cancer Information Service