# Presentation: 575621

## ENG Advisory Committee May 11, 2005

**BES**
**OVERVIEW**
**Bruce Hamilton**
**Acting Division Director**

## BESStructure & Funding Profile 

**Three (3) Clusters:**
- Biochemical Engineering/Biotechnology **(BEB)**
- Biomedical Engineering/Research to Aid Persons with Disabilities **(BME/RAPD)**
- Environmental Engineering and Technology **(EET)**
**Each cluster is funded at about 1/3 of BES’s overall budget (~ $50 million/year)**

## BES Team

**Program Officers:**** **
**	****Pat Brezonik****	****	****Gil Devey (PT) ****	****   ****	****Fred Heineken****	**
**	****Lenore Clesceri (PT)****	****Cindy Ekstein****	****   ****	****Marshall Lih**
**	****Semahat Demir****	****Leon Esterowitz****	****   ****	****Tom Waite**
**	****Mike Domach (PT)****	****Bruce Hamilton (ADD)   ****	****Bill Weigand (PT)**
**	****	****	****	**
**Support Staff:**
**	****Toni Baker****	****	****LaWanda Prailow       ****	****Sherri Swann**
**	****Eula Patterson****	****Marcia Rawlings****	****	****LaTanya Darby**
**	****Sunny Phelps****	****Joyce Simpson****	****	**
**	****	****	****	**

## BES Draft VisionAn Aspiration for the Future...

**BES ****is an important and significant**
** **_***Catalytic Driver***_** ****for the role of **
**Biology**** and the ****Environment**** **
**in advancing the**
**Frontiers of Engineering**** **
**research, innovation, and education.**

## Why the Role of BES Is As a Catalytic Driver:

**1. Resources needed.**
**2. At NSF,**** the involvement of ****Engineering****  with ****Biology**** and the ****Environment**** has become pervasive,****going way beyond ****BES.**

## Biology: All 6 NSF ENG DivisionsSupport Biology-Oriented Awards

**BES: All aspects of biology and engineering**

**CMS: Biomechanical Eng (e.g., bone biomaterials)**

**CTS: Biotransport Eng (e.g., blood flow fluid dynamics)**

**DMII: Engineering Health Care Delivery**

**ECS: Many aspects of biology and engineering **
**	****	****(e.g., biomedical imaging)**

**EEC: Centers, Dept. Reform (biology and engineering)**

**Notes:**
Suggestion: Delete the word “Major.”  IT can cause confusion.  It these are the major programs, what are the minor?  Also, could imply that the whole program budget is spent on biomass research.   

## CISE Directorate AlsoSupports Engineering/Biology-Oriented Awards

**Example--**
**ITR 0205741:  “Simulation-Based Medical Planning for Cardiovascular Disease”**
**PI = Charles Taylor**
**Department of Bioengineering**
**Stanford University**
**$3.7 million over 5 years**

**Notes:**
Suggestion: Delete the word “Major.”  IT can cause confusion.  It these are the major programs, what are the minor?  Also, could imply that the whole program budget is spent on biomass research.   

## EHR Directorate AlsoSupports Engineering/Biology-Oriented Awards

***Example (undergraduate course):***
**NSF 0231313**
**“****Development of Educational Materials that Strengthen Students’ Problem-Solving Skills for a Bioengineering Fundamentals Course”**
**PI = Ann Saterbak**
**Rice University**
**$75K over 2 years**

## And for the case of the Environment:

**Just as for the pervasiveness of**** ****Biology ****in**** ****Engineering****,**
**so also for the pervasiveness of the ****Environment ****in ****Engineering****.**
** **
**(goes way beyond BES, therefore the role of BES as *****Catalytic Driver****** *****is appropriate)**

## BES Draft Mission 

**Research and Innovation:**** Enable and facilitate the deployment of new innovations in BES’s fields in service to society for use in the medical, biotechnology, and environmental arenas**
**Education:**** Advance bioengineering and environmental engineering through the development of creative programs by new and diverse faculty (example: Emphasis on ****CAREER awards****, including ****under-represented group PECASE awardees****)**

## BES Strategies 

**To pursue our Vision and Mission,**
**BES has evolved **
**7 Key Strategies**
**(Time to cover only 4)**

## BES Strategy #1 

**Develop and support **
** ****the best and the brightest**** researchers, innovators, & educators**
**in BES’s fields,  **
**with one emphasis being on **
**new faculty**

## BES Strategy #1: Develop and support the best and the brightest researchers, innovators, & educators in BES’s fields, with one emphasis on new faculty. 

**Examples:**
**2004 Waterman Award Winner:**** Kristi Anseth (1998 BES CAREER awardee).**
**1999 Waterman Award Winner:**** Chaitan Khosla (1994 NSF Young Investigator awardee from BES).**
**2004 IOM Inductees:**** Cato Laurencin (BES PI from early in career) and Frances Arnold (1989 BES PYI; also NAE in 2000).**
**2002 HHMI $1 Million Undergraduate Educator Award Winner:**** Rebecca Richards-Kortum (1991 BES PYI).**
**2002 NAE Draper Award and 1998 Lemelson Invention Prize Winner: ****Bob Langer (long-time BES PI, starting early in his career).**
**2002 NAE Inductee (Industrial Ecology): ****Tom Graedel (BES is principal source of support, starting early in his academic career)**
**2005 NAE Inductees: ****George Georgiou**** (1987 BES PYI) and Harvey Blanch (long-time BES PI).**
**Future Goal: ****Develop and support more winners!**

## BES Strategy #2 

**Aggressively pursue and implement **
** ****partnerships with other ENG divisions, directorates, and agencies,**** even if tolerance of high risk is required**
**(e.g., solicitation risk)**

## BES Strategy #2: Aggressively pursue and implement partnerships with other ENG divisions, directorates, and agencies.

**Examples:**
**Metabolic Engineering:**** NSF, NIH, DOE, EPA, NASA, NIST, DOD, USDA**
**MATES:**** NSF, NIH, NIST, DOD, FDA, DOE, NASA**
**QSB:**** ENG (5 divisions), BIO, MPS, CISE.**
**Biophotonics: ****NSF, NIH, DARPA.**
**Multiscale Bio Modeling: ****NSF, NIH, NASA, DOE.**
**CRCNS: ****ENG (BES, ECS), CISE, BIO, SBE, NIH.**
**MUSES: ****ENG (5 divisions), SBE, CISE, MPS**
**IGI: ****ENG (BES, ECS), CISE, NIH, NASA**
**Forum on the Interface of the Life Sciences and Physical Sciences: ****NSF, NIH, NASA, NIST, DOE, USDA, EPA, DOD, FDA, NOAA**
**Future Goal: **
**Additional innovative partnerships with high-return leverage.**

## BES Strategy #3 

**Dynamically interact, **
**through extensive outreach, with**
** ****universities, industry, foundations, non-profits, other agencies, and professional societies and topical meetings.**

## BES Strategy #3: Dynamically interact, through extensive outreach, with universities, industry, foundations, non-profits, other agencies, and professional societies and topical meetings.

**Examples:**
**Universities:**** Workshops (e.g., for CL*****EAN*****ER, at Stanford, U. of Minn., Duke, U. of Iowa, RPI)**
**Industry:**** BES Biochemical Engineering Workshop (Amgen, Biogen, Chiron, Genencor, Genetics Institute, engeneOS Biosystems, Inc.) and 2005 Metabolic Engineering Conference with industry.**
**Foundations:**** Whitaker, HHMI.**
**Non-profits: **** MdBio, Inc., the National Academies.**
**Professional Societies: ****AIChE, ACS, IEEE, BMES, AIMBE, AEESP, WEF, ASEE, SWE, WEPAN and others.**
**Future Goal: ****Strengthen outreach, with high-return (intellectual, financial, diversity).**

## BES Strategy #4 

**Create and implement**
**“****Big Ideas.”**

## BES Strategy #4: Create and implement “Big Ideas.”

**Examples:**
**	****	****- CL*****EAN*****ER**
**	****	****- Engineering Systems Biology**
**	****	****- Biophotonics (BP) / IGI**
**Future Goals: **
**	****	****- Implement CL*****EAN*****ER, include other agencies.**
**	****	****- Extend QSB and include other agencies.**
**	****	****- Grow BP / IGI partnership with other agencies.**

## BES Draft VisionAn Aspiration for the Future...

**BES ****is an important and significant**
** **_***Catalytic Driver***_** ****for the role of **
**Biology**** and the ****Environment**** **
**in advancing the**
**Frontiers of Engineering**** **
**research, innovation, and education.**