BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 075162

## DAQ 100  - (Jeff Landgraf)

- Only write clusters to .daq files
- Remove some current bottlenecks in DAQ
-    	- Cluster finder optimization
- 	- Formatting optimization / bypass
- 	- Formatting buffer management

- This Gives us:

-  ~5-fold reduction in data size
-  High instantaneous rates approaching
- 100 Hz  (Min Bias  ~50MB/sec)
- 50 Hz (Central ~100MB/sec)
-  Better dead time management
- Last year 20 Hz MinBias  80-100% dead
- This year 20 Hz MinBias  ~20% dead
-  Full buffered use of the 30 MB/sec (2.7 TB/day) HPSS link
- Could approach 1.3 million Central/day
- 		5 million MinBias/day

- * Last years record:  2.0 TB
-  	     210,000 Central events

## STATUS

- DAQ technical bottlenecks
-  Cluster finder optimization					(done)
-  Formatting optimization / bypass				(done)
-  Formatting / cluster buffer management			(done)
-  Second myrinet card on BB					(done)
-  Study Disks on BB			  (done / not implemented)
- Clustering / interface issues
-  Cluster finder  Offline Chain				(done)
-  Cluster finder physics evaluation			           (ongoing)
-  Gain Corrections and T0 corrections need to be done online
- Mechanism inside DAQ exists
- Need procedures for the corrections 		             (august)
- 		(Automated & manual)
- Need procedures for monitoring them
- 		(Automated in EVP & Shift requirements)
- Offline chain needs to be aware of correction status

##            Comparison between 

-      DAQ / TCL cluster finders...

|  | /t3 (daq) | /t4 (tcl) |
| --- | --- | --- |
| nEvents | 9123 | 9123 |
| nReconstructed | 9011 | 9120 |
| nVtx | 5243 | 5310 |
| nGlobal | 6.28E6 | 6.46E6 |
| nPrimary | 2.54E6 | 2.54E6 |

##  More events with large number of primary tracks

-  More events with large number of primary tracks
-  Fewer events with large number of global tracks

- DAQ cluster finder gets...

## DAQ Cluster finder gets...

-  Smaller RMS distance from global track to hits
-  More short tracks  (more track splitting)
-  Better peak for long tracks

- Why? Consistent with wide distribution of tracking cuts in tcl

## 2-Hit Resolution  (Fabrice Retiere)

## Track Splitting  (Mercedes Noriega)

## Track Merging  (Mercedes Noriega)

## Correlation Functions  (Mercedes Noriega)

- 3D correlation functions:

## Summary

-  We should be able to turn on clusters for next run.
-  Initial studies on the quality of the clusters are promising
-  Responsibility for evaluation of the cluster finder should
-   be (and is) moving to the physics groups...
# Presentation: 684698

**Top**

**Higgs**

**The HiT**

## 

What’s the Higgs mass?

The Higgs vev is
<>=246 GeV

The Top quark mass is 

Mtop=246/sqrt(2)=174 GeV

           The Higgs boson mass is

Mhiggs=174/sqrt(2)= 123 GeV

Disclaimer: We were told back in 1977 that the Top
                    quark mass is Mtop=3*Mbottom~14 GeV

**What’s the Higgs mass?**
- The Higgs vev is
- <>=246 GeV
- The Top quark mass is
- Mtop=246/sqrt(2)=174 GeV
-            The Higgs boson mass is
- Mhiggs=174/sqrt(2)= 123 GeV
- Disclaimer: We were told back in 1977 that the Top
-                     quark mass is Mtop=3*Mbottom~14 GeV

## 

HiT – “workshop” channels

**HiT – “workshop” channels**

**pp      W+Higgs**
**W      ********+****E****T**
**Higgs        ****bb**

**pp      tt      WbWb       ****e****+********+****2b****+ ****E****T**

## 

HiT – Higgs and Top

(Monday, June 19, 2000)

Introduction, news - Boaz/Meenakshi

Top Quark Physics - Su Yong Choi

Higgs Boson Physics - Ela Barberis

Plans, discussion - Meenakshi/ Boaz + All

**HiT – Higgs and Top**
**(Monday, June 19, 2000)**
**Introduction, news - Boaz/Meenakshi**
**Top Quark Physics - Su Yong Choi**
**Higgs Boson Physics - Ela Barberis**
**Plans, discussion - Meenakshi/ Boaz + All**

## 
HiT – Higgs and Top

(Thursday, June 22, 2000)

News - Boaz/Meenakshi
Trigger Simulator Status – Dugan O’Neil
Proposal for a HiT workshop – Meenakshi/Boaz
Reports regarding the two selected analyses:
Monte Carlo
Triggers
Event Access and Selection
Jets
Electrons
Muons
Tau
Missing Energy
b-tagging
Calibration
What’s next?

**HiT – Higgs and Top**
**(Thursday, June 22, 2000)**
**News - Boaz/Meenakshi**
**Trigger Simulator Status – Dugan O’Neil**
**Proposal for a HiT workshop – Meenakshi/Boaz**
**Reports regarding the two selected analyses:**
- Monte Carlo
- Triggers
- Event Access and Selection
- Jets
- Electrons
- Muons
- Tau
- Missing Energy
- b-tagging
- Calibration
**What’s next?**
# Presentation: 486187

## Regional Planning Activities

- _DOE Congestion Study_
- WCATF summarizing existing studies, defining “corridor” and developing “congestion criteria”
- SSG-WI finishing up 2015 IRP/RPS Reference case
- CDEAC to analyze 4 clean energy resource scenarios with ABB
- High Efficiency
- High Renewables
- Clean Fossil
- Combination alternative(?)
- WCATF to run other identified studies and complete DOE study

## Regional Planning Activities

***2006***

***Jan***

***Feb***

***Mar***

***Apr***

***May***

***Jun***

***Jul***

***Aug***

***Sep***

***Oct***

***Nov***

***Dec***

***WECC Board Meeting***

***Congestion Study due to DOE***

***Congestion Study due to Congress***

***WECC Transmission ***
***Expansion ***
***Workshop***

***Final Dec***
# Presentation: 373975

## EPA  NAQC 2005   San Francisco, CA

**Optical Transmissometer****:**
**Rapid optical analysis of filter samples**
**for EC and UVPM content**
- Tony Hansen
- Magee Scientific Company
- Berkeley, CA

## Diesel Exhaust    -   Listed Air Toxic

- Toxic Components : ***Specific Compounds ***require ***Specific Chemical Analyses***
- Accompanying components may permit more rapid detection by optical means:
- 	***Black Soot*** and ***UV-Absorbing Material***

## Analytical Premise

- Optically-absorbing material is a         ***surrogate tracer*** for diesel exhaust.
- 	“Black” carbon (‘BC’, ‘EC’)
- 	“UV-absorbing material” (‘UVPM’)
- Optical analysis is fast, sensitive, can be performed in real time or on filter samples.

## Analytical Method  -  Optical Absorption

## Optical vs. chemical analyses

- “Harvard 6 Cities Study”

## Analytical Instrument  :  AethalometerTM

- While continuously collecting sample, measures ***optical absorption*** in real time    at 2 wavelengths (880 nm and 370 nm UV)
- Converts ***optical absorption*** to                   ***mass concentration*** of BC and UVPM
- Real-time data:  1 second / 1 minute / 1 hour

## Analytical Instrument  :  AethalometerTM

- 19-inch rack mount model

## “Portable” AethalometerTM

- Battery-powered: 1-, 2- or 7-wave optics

## Large Networks / Baseline Monitoring

_**The Need**_:
- 	Time-integrated BC measurements at many locations
_**The Problem**_:
- 	Real-time instrumentation is expensive

## Analytical Instrument:Optical Transmissometer

## Principle of Operation:

- Performs _optical transmission analysis_ of aerosol samples collected on filter media
- Optical components and wavelengths are _identical_ to those in the Aethalometer
- Calculates absorption (‘ATN’)

## Features:

- Accepts 25, 37 and 47-mm diameter filters.
- Fully automatic operation with second position for reference blank filter.
- Barcode scanner for sample ID.
- COM port transmits optical and barcode data to laptop with software provided for direct import into spreadsheet.

## Optical Transmissometer:accepts 47, 37 and 25 mm. diam. filters

## Applications:

- Routine analysis of time-integrated filter samples

## Summary

***Black Carbon*** and ***UV-Absorbing Carbon*** are good surrogates for diesel exhaust***.***
- The _Optical Transmissometer_ uses the same optical analysis as the Aethalometer to determine the ***BC*** and ***UVPM*** content of filter-collected samples.

## Acknowledgments

- Harvard School of Public Health
- U.S. Environmental Protection Agency
- For further information:
**www . mageesci . com**
# Presentation: 307836

## Strategic Plan Performance Assessment and Reporting

- Appropriate target setting and data verification are critical to a viable performance assessment
- Dr. Richard Beck
- Director, Planning and Performance Management

## Evolution of Planning and Performance 

**1993: Government Performance and Results Act**
**Formalized government-wide practice of strategic planning with performance assessment**
**Adds performance aspect** to see how well you were progressing against your advertised plans
- Implications for budget decisions
- But first efforts to focus on developing plans with annual performance targets and reporting
**Greatly increased focus on outcome / results** vs. government performance being expressed often in terms of outputs / products of process
- How do you know if a program is truly effective if you do not measure its benefits to the American public
- A means to answering the age-old question as to whether government programs  are “effective”

## Benefits of Performance Assessments

**Introspective**
- Can I clearly define what I am trying to achieve and its benefits?
- Do I have a plan, especially in terms of targets that express what I expect to achieve, how much, and when?
- How am I progressing against those targets, and if I didn’t reach those targets, why not? What should I do differently?
- Performance assessment is not just a case of goal met vs goal not met; it’s understanding why it was not met and determining what needs to be done and if I still want to achieve it
**Readily provides insight as to the nature of the task, its benefits, and range of resources required to decision makers and external stakeholders**
**Builds credibility in your ability to deliver **
- Not only do I have a plan but I am willing to track my progress openly against targets
- I have adequate knowledge of the topic to set targets and to determine the reasons for not making the targets and the subsequent corrective actions
- Helps promote support for your program
- Traceability/Continuity of performance targets from start of performance period to evaluation and data verification is crucial to demonstrate a responsible performance process

## Target SettingExample for the FY 2007 Budget

## Policy References

- “Policy for Establishing and Adjusting GPRA Strategic Plan Performance Measure Targets”
- November 9, 2004 memo from AS/PMB
- “Performance Data Credibility”
- Detailed data validation and verification requirements
- January 16, 2003 memo from AS/PMB
# Presentation: 859393

## Brazing for Furnace ComponentsMaterials Resources International (MRi)North Wales, PA

**ACCOMPLISHMENTS**
- Developing braze techniques for the fabrication of a furnace for space experimentation.  Furnace temperatures of 1000 - 1450C have been targeted in which Fe, Mg, and SiO2  materials will be rapidly heated and vaporized in argon atmospheres.
- MRi has proven the feasibility of brazing graphite to molybdenum, graphite to alumina and molybdenum to alumina.
- Project is developing several preform methods: paste, tapes, press and sinter, and hot isostatic pressing.
**COMMERCIALIZATION**
- Developed five new materials systems (Cu Ti-Mo, BNi5-Ti-Mo,NiCr-Ti-Mo, BNi-5-TI-SiC, & NiCr-Ti-SiC).
- MRi has received two commercial orders, one from Lockheed Martin and the other from EG&G Sealol.
- Market potential for such brazing preforms exceeds $25M annually with applications in chemical, power generation, aerospace, and cutting/tooling industries.
- 1998 Sales of $30K, expected 1999 sales $75K.

**S****mall**
**B****usiness**
**I****nnovation**
**R****esearch**

- 1995 Phase II; 5/26/98; SS5-011

**GOVERNMENT SCIENCE/APPLICATIONS**
- The project goal is to use MRi’s WideGapTM brazing technology to fabricate heating elements and crucibles for constructing integral furnaces for Space Shuttle experiments.
- Other applications include rocket engine ducts and nozzles.

**Goddard Space Flight Center**

**INNOVATION**

- Points of Contact:
- 	-  NASA - Dr. Joe Nuth - 301-286-9467
- 	-  MRi - Dr. Ron Smith - 215-616-0400
- 	-  email - solution@mri-bluebell.com

- WideGapTM brazing technology is a powder based/braze alloy preform that permits high temperature brazing for joining dissimilar, refractory and/or refractory composite materials.
# Presentation: 372796

## FCC EN BANC PRESENTATION 

- January 29, 1998
- Heather Burnett Gold
- President, ALTS

## Roadmap to Local Competition

- Late 1980s
- Niche players
- 1992 Interconnection Order
- 1996 Telecommunications Act
- First ever national framework for effective local competition
- 1997 and the future
- Implement effective local competition

## Redefinition of Local Infrastructure Model

- Customer demands have forged a new model
- ATM networks
- SONET-based fiber
- Broadband wireless
- Frame relay
- Local hand-off for fast-packet Internet providers

## Characteristics of the Local Market

- Incumbent begins with 100% of the market
- All dialtone providers must interconnect
- Facilities-based competition is highly capital intensive, and there are significant volume-dependent economies of scale
- High reliability is essential
- Multi-tiered regulation must be confronted

## YE97 Yardsticks of CLEC Progress

- Over 100 CLECs
- $2.7B 1997 Revenue
- 1.4M access lines
- 50% on-net, 20% unbundled loops, 30% TSR
- $14B in capital raised since passage of the Act

## However, in comparison...

- CLECs*
- $2.7B 1997 Revenue
- $26B enterprise value
- 1.4M access lines
- 50% on-net, 20% unbundled loops, 30% TSR
- 1998 access line projection of 3M

- ILECs*
- $101B 1997 Revenue
- $400B enterprise value
- 161M access lines
- 1998 access line projection of 168M

- *All numbers are approximate

## Impediments to Progress

- Interconnection agreements lack measurements, standards and enforcement mechanisms to provide quick and effective dispute resolution
- Network build-out requirements are extensive
- Labor intensive construction
- Major switch installations
- Access to rights-of-way
- Access to private buildings
- Systems Development
- Systems Integration between carriers

## FCC 1998 Plan of Action:Factors that would Speed Effective  Competition

- Factor: 		Interconnection agreements are	 			about to be renegotiated
- Solution:	- Require performance 					   measurements and standards 				- Require compliance penalties 				- Initiate expedited  					  dispute/resolution process

## FCC 1998 Plan of Action:Factors that would Speed Effective  Competition

- Factor: 		Access to rights-of-way must 	 			be reasonable and nondiscriminatory
- Solution:	- Work with the states to ensure 			   cities do not unfairly regulate  		   	   or tax new entrants

## FCC 1998 Plan of Action:Factors that would Speed Effective  Competition

- Factor: 		Systems integration (OSSs)  	 			standards and processes must be 			established, tested and put in place
- Solution:	- National standards to promote 			   economic and efficient handling of 			   inter-company traffic and 				   transactions

## FCC 1998 Plan of Action:Factors that would Speed Effective  Competition

- Factor: 		Inter-company pricing of services 			needs to be managed during the 			transition to full local competition
- Solution:	- Pro-competitive pricing for 				   interconnection, unbundled 				   elements and resale
# Presentation: 127660

## ELIMINATION OF REQUIREMENTS FOR TREATMENT OF TRICHINA (TRICHINELLA SPIRALIS)

**Amelia K. Sharar, Ph.D.**
**United States Department of Agriculture**
**Food  Safety and Inspection Service**
**Office of Policy, Program Development, and Evaluation**
**Technical Analysis Staff**

## ELIMINATION OF REQUIREMENTS FOR TREATMENT OF TRICHINA (TRICHINELLA SPIRALIS)

**Amelia K. Sharar, Ph.D.**
**United States Department of Agriculture**
**Food  Safety and Inspection Service**
**Office of Policy, Program Development,****and Evaluation**
**Technical Analysis Staff**

## Proposed Rule	

**Remove the provisions for the prescribed treatment of pork and products containing pork to destroy *****Trichinella spiralis***** or trichina under ****9 CFR 318.10 for both RTE and not-RTE products**

## RTE Products

**Cooked products**** **
**If process used achieves the proposed lethality performance standards for Salmonella, the process should eliminate trichina.**

**Notes:**
Time 

## RTE Products

**Salt-cured, dried and fermented products**
**If lethality requirements for *****Salmonella***** and also *****E. coli***** O157:H7 for fermented products are achieved, it is likely that trichina will be destroyed.**** **
**No published studies comparing lethalities of *****Salmonella***** and *****E. coli *****O157:H7 to destruction of trichina in these products.**** **
**If establishment identifies trichina as a hazard likely to occur, the establishment has to ensure that the process, used effectively, eliminates trichina.**

## Not-RTE Products

**Products that are raw may appear to have been cooked because they contain ingredients such as wine, paprika and other spices and curing agents that masked their raw appearance**** **
**These products maybe eaten rare or undercooked because of their appearance.**
**Products are raw and bear safe handling instructions on their label.**

## Not-RTE Products

**Trichina treatment provisions on these raw pork products are overly prescriptive and are contrary to HACCP.**** **
**Proposed rule would provide establishments the flexibility to determine whether they need to treat products to eliminate trichina.**

## Not-RTE Products

**HACCP plan must address trichina if the establishment identifies it as a hazard likely ****to occur.**** **
**HACCP plans for these products may provide for conspicuous labeling and instructions for fully cooking product for safety.**

## Incidence of Trichinosis

**First implementation of trichina regulations**** **
**Reported decrease incidence of trichinosis**** **
**Meat and Poultry Hotline and Industry Consumer surveys**

## National Trichina Certification Program

**Cooperative agreement among USDA agencies (APHIS, ARS, CSREES, FSIS), National Pork Producers Council and two pork producers**

## Trichina and HACCP

**lethality that achieves a 6.5 log reduction ****of *****Salmonella***
**trichina treatment**
**trichina certified herd**
**safe handling instructions**
**cooking instructions**
**conspicuous labeling**
# Presentation: 717838

## Truck Transportation During Natural Disasters: Florida’s Experience

**Lt. Colonel David B. Binder**
** ****Deputy Director**
**Florida Department of Transportation**
**Motor Carrier Compliance Office**

## Areas of Focus	

- Fuel
- Emergency Orders and Permits
- Pre-staging
- Road closures and detours
- Traffic flow

## Fuel

- Trucks are less impacted than cars due to fuel capacity
- Refueling for trucks at Logistical Staging Areas (LSA’s)
- Fuel trucks for first responder vehicles are given escorts by  marked DOT/MCCO patrol cars

## Relief From Regulations

- Governor’s Executive Order triggers relief from safety regulations pursuant to 49 CFR part 390.23 which includes hours of service
- Order provides for revised size and weight regulations (up to 95,000 lbs with 5 axles and outer bridge of not less than 51’)
- Order also provides for relief from IFTA and IRP requirements

## Industry Notifications

- Trucking Associations
- CVSA
- FMCSA
- Individual Carriers
- Communication with neighboring states
- Web site (_[www.dot.state.fl.us/mcco](http://www.dot.state.fl.us/mcco)_ or _[www.floridatruckinginfo.com](http://www.floridatruckinginfo.com/)_)

## Pre-Staging

- FEMA relief supplies pre-staged at LSA’s and at the comfort stations at DOT weigh in motion (WIM) facilities
- Other trucks are welcomed at the WIM Comfort Stations
- Locations are in an area that is not expected to be impacted but close enough to respond quickly

## FDOT Comfort Station

**FDOT Comfort Station**

## Road and Bridge Closures

- Erosion
- Deck displacement
- Obstructions by objects
- Obstructions by debris
- Flooding

## Interstate 10 Bridge

**Interstate 10 Bridge**

## Interstate 10 Bridge

## Mississippi State Bridge

## U. S. 90 Bridge in Mississippi

## Bridge Approach Washout

## Roadway Erosion

**Roadway Erosion**

## Unusual Roadway Obstruction

**Unusual Roadway Obstruction**

## Unusual Roadway Obstruction

**Unusual Roadway Obstruction**

## Motorist Information Systems

- Dial 511
- _[www.fl511.com](http://www.fl511.com/)_
- _[www.floridadisaster.org](http://www.floridadisaster.org/)_
- Variable message boards
- Signs
- Motorist information radio systems

## Special Considerations

- Driver should be prepared to meet their own sustenance needs for at least 3 days
- Local curfews may effect deliveries during night time hours
- Request for law enforcement escorts should be limited to actual security needs
- Anticipate bridge closures when winds are 39 mph or greater

## Detour Routes

- Bridge damage and roadway obstructions may require extensive detours
- Vehicle size and weight may require additional detours

## Florida’s 2006 Legislative Cargo Security Summit 

- The 2006 summit will be held on January 25th and 26, 2006 at the Ramada Inn, North Monroe Street in Tallahassee.
- This summit is co-hosted by the International Cargo Security Council, the Florida Trucking Association and Florida's Statewide Truck and Cargo Theft Task Force.
- Registration information is available online at www.dot.state.fl.us/mcco

## Questions?
# Presentation: 545350

## ICR HTP WG, September 26 2007

**GForge: **_**[https://](https://gforge.nci.nih.gov/projects/htpd/)**__**[gforge.nci.nih.gov/projects/htpd](https://gforge.nci.nih.gov/projects/htpd/)**__**[/](https://gforge.nci.nih.gov/projects/htpd/)**_
**Issues raised during F2F**
- Semantics and security of end-point references
- Standardized APIs for common EPR ‘choreography’
- Specification of large data objects
- Need for additional grid-level infrastructure
- These need to be prioritized and acted upon as appropriate
- 	1: Arch; 3: VCDE; 2, 4: caGrid
**Additional issues arising**
- Where do GridFTP benefits come from?
- Transfer? Avoiding XML?
- Have we adequately addressed issues of XML parsing – large, complicated objects, rather than numerous simple objects
- Other issues ??
**Next meeting (3 October) cancelled**
# Presentation: 495377

## Vibrational characterization of glasses using IR reflectance and Raman scattering  P. Boolchand, University of Cincinnati, DMR-0315491

-    ●  Recently, we  have synthesized pure AgPO3 glass samples with Tgs substantially higher than those reported in the literature. AgPO3  forms a chain-glass consisting  of  PO4 tetrahedra (Q2 species in the NMR notation). In Raman and IR, we observe  symmetric and asymmetric modes (red) of PO4 units respectively, and note that they follow the exclusion rule. Presence of monomers composed of small- and large-rings in addition to long-chains contributes to the richness of observed lineshapes.  Tgs drop remarkably, and  vibrational features  evolve systematically as water is co-doped in AgPO3 glass.
-    ●    The IR response was obtained using a specular reflectance accessory to an 870 bench from ThermoNicolet. Raman scattering was excited in the visible (514 nm) using a dispersive T64000 unit from JY-Horiba.

##  Vibrational characterization of glasses using IR reflectance and Raman scattering  P. Boolchand, University of Cincinnati, DMR-0315491

- Education**-**
-  ●The versatile FTIR (Nicolet Nexus 870) with a  Raman module (top) is used to illustrate physical principles of IR and Raman scattering as vibrational probes of local structures in glasses. The  complimentary nature of these probes is demonstrated in a graduate course (ECECS 810).  Group theoretical predictions are tested against  experiments.
-  ● The instrument is  also used by graduate students of the PI ( bottom) and of faculty colleagues and of collaborators to complete their M.S. and Ph.D. Dissertation work.

- Outreach-
-  ●  IR and Raman scattering as  non-invasive and trace analysis probes of materials is illustrated to undergraduate and high- school students.
-  ● The instruments are also made available to industry desiring characterization of  samples.
# Presentation: 804748

## LH / Q3012R Molecular Biology, Immunology, & Genetics of Coagulation Factors

***Jay Lozier, M.D., Ph.D.***
***Principal Investigator***
***Report to the Blood Products Advisory Committee, September 29, 2005 on February 25, 2005 LH Site Visit***

## LH Regulatory Issues:Inhibitors to Factors VIII/IX

***Public Health Impact/Mission Relevance***
- Antibodies to coagulation factors prevent the use of therapeutic products in ~20% of patients with hemophilia.
- Understanding factors that control whether patients make antibodies to therapeutic products is important for evaluation of their immunogenicity.

***LH / Q3012R Lozier, PI***

## Research Questions/Problems

- Are there genetic factors in patients that influence inhibitors?
- Are there animal models in which to study the problem?
- How can we leverage FDA resources to study this problem using outside resources and collaborators?

***LH / Q3012R Lozier, PI***

## Mouse Animal Models

-     *Using genetically well-characterized inbred mouse strains we have shown:*
- MHC genes, T-cell receptors, and zinc--2-glycoprotein 1 genes influence the antibody response to human factor VIII
- MHC genes and to a lesser extent, cytokine genes (IL10, Interferon-) control the antibody response to human factor IX.

*Lozier, et al., Blood  2005;105:1029-1035.*

***LH / Q3012R Lozier, PI***

## Hemophilia A Dog Model

- The Chapel Hill hemophilia A dogs have a gene inversion identical to that in ~40% of humans with severe hemophilia A.
- The bleeding phenotype is identical to human hemophilia A.
- The dogs can & do make inhibitors when treated with dog factor VIII.

*Lozier  et al, PNAS 2002;99:12991-12996*

***The Chapel Hill hemophilia A dogs are an ideal model in which to study mechanisms for inhibitor antibodies:***

***LH / Q3012R Lozier, PI***

## Future Directions: Pharmacogenomics I

**	**We will test the hypothesis that genes identified in the mouse have similar influence on inhibitor antibodies in hemophilia dogs, and the hypothesis that differences in the normal factor VIII protein can influence development of inhibitors in hemophilia A.

***LH / Q3012R Lozier, PI***

## Future Directions: Pharmacogenomics II

- 	We will test the hypothesis that candidate genes identified in the mouse have similar influence on inhibitor antibodies in humans with hemophilia A.

***LH / Q3012R Lozier, PI***

## Jay Lozier, M.D., Ph.D., Principal Investigator
Nahid Tayebi, Ph.D., Staff Fellow
Laura Wood, B.S., Biologist

Pei Zhang, M.D., Collaborator (DH/LPD)

Timothy Nichols, M.D., Collaborator (UNC)
James Goedert, M.D., Collaborator (NCI)
Marjory Brooks, D.V.M., Collaborator (Cornell)

- Nahid Tayebi, Ph.D., Staff Fellow
- Laura Wood, B.S., Biologist
- Pei Zhang, M.D., Collaborator (DH/LPD)
- Timothy Nichols, M.D., Collaborator (UNC)
- James Goedert, M.D., Collaborator (NCI)
- Marjory Brooks, D.V.M., Collaborator (Cornell)

-  **Personnel/Collaborators**

***LH / Q3012R Lozier, PI***
# Presentation: 481743

## MRSEC Northwestern University DMR-0076097 IRG2 Seng-Tiong Ho, Tobin Marks, Bruce WesselsDevice Optimization and Characterization of EO Modulators Based on MOCVDGrown BaTiO3 Thin Films and Organic Polymeric Materials

**In collaboration with Prof. Bruce Wessels’ group, Ho’s group has (1) derived the optimal performance geometry of electro-optic (EO) modulators based on thin films of BaTiO3 grown on MgO substrate for a wide range of film thickness, (2) demonstrated BaTiO3 based EO modulator with >2GHz bandwidth, (3) investigated contact poling effect with respect to external bias voltage.**
**In collaboration with Prof. Tobin Marks’ group, successfully (1)**
**engineered the electrical/optical properties of transparent conducting oxides (TCO) including conductivity, refractive index, and optical loss, (2) fabricated unconventional TCO electrode based EO modulators with poled polymer and BaTiO3 thin films, (3) achieved factor of 3-4x improvement on the half-wave driving voltage of EO modulators.**
# Presentation: 089018

## Weissleder et al., NEJM 2003;348;2491-2499

**Notes:**
*******************************
Dear Dr. Weissleder,

October 1, 2006 will mark the 10th Anniversary of the establishment   of the Cancer Imaging Program at the NCI.  To highlight the impact   that CIP-supported research has had on the field of in vivo cancer   imaging, we plan to compile examples of that research for use in   presentations to the scientific community as well as the NCI/NIH   leadership.

On behalf of the CIP planning committee, we would like to invite   you to contribute some very brief materials representing an example  
of CIP-supported research that you have conducted on nanotechnology   for this series of presentations.  We would like the following, in   electronic form:

1)  A single image representing your nanotechnology research.  The   image must be a minimum of 720 x 486 at 300 dpi.  A jpg format is  
preferred, but tiff and pdf will also be acceptable.

2)  A one sentence quote about the impact the funding has had on   your research and/or on the field of cancer imaging

3)  A photograph of yourself to accompany the quote in the  presentation

We are likely to use these materials in presentations in the   technical exhibits area at a variety of scientific meetings.   
Please send your submissions Sept. 15, 2006 to Anne Menkens  (am187k@nih.gov).

## Weissleder et al., Nature Biotech 2005;23:1418-1423

**Notes:**
In one approach, we have previously used small molecules for targeting. Indeed several hundred small molecules can be attached to 30 nm partciles which than acts as ”Velcro”. We have used this approach to identify agents with low Mø uptake agents, and those with high affinity for cancer. (advance)
Without going into details (as it is published) we were able to develop one agent with specificity for pancreatic cancer. Indeed ratio imaging of magnetofluorescent NP without (top) and with (middle) targeting ligands at different wavelengths now allows us rapidly screen compounds in vivo and thus rapidly identify imaging agents of promise
# Presentation: 513489

## Research to Operations:The Pathway to Operational Implementation

- Presented at the 3rd National Surface Transportation Weather Symposium, July 28, 2007
- by
- Leland D. Smithson, PE
- AASHTO SICOP Coordinator

## Research to Operations

- Identify User Needs
- Survey
- Stakeholder Meetings
- Foundational Research and Reports Address User Needs
- Solutions address the problems
- Solutions are reasonable and affordable
- Identify the payoff

## Pathway to Operational Implementation

- Proactive Snow & Ice Control Operations Foundational Research
- SHRP H-350, *Road Weather Information Systems *by Ed Boselly, 1993
- SHRP H-385, *Development of Anti-icing Technology,* by Robert Blackburn, 1994
- FHWA, *Manual of Practice for an Effective Anti-icing Program: A Guide for Highway Maintenance Personnel, *1996

## Pathway to Operational Implementation

- Identify and address the barriers
- Institutional issues
- Funds for equipment, chemicals & facilities
- Funds and time for training
- Cultural change
- Learn from the success of others
- Identify the champions
- Provide field demonstrations
- Education
- Develop effective methods of teaching

## Pathway to Operational Implementation

- Address Emerging Problems
*Benefit/Cost Study of RWIS and Anti-icing Technologies,* by Ed Boselly, 2001
- NCHRP 526, *Snow & Ice Control: Guidelines for Materials & Methods, *2004
- NCHRP 577, *Guidelines for the Selection of Snow & Ice Control Materials to Mitigate Environmental Impacts,* 2007

## Pathway to Meeting Tomorrows Needs

- Deepen the science and optimize the results
- FHWA MDSS, MODSS & Clarus
- Benchmark the performance
- Develop reliable processes
- Share the results
_**COMMUNICATIONS **_is the glue that holds the improvement process together!!!

## Research to Implementation:The Pathway to Operational Implementation

**QUESTIONS**
**OR**
**COMMENTS?**
# Presentation: 325968

## National Institute on Drug Abuse (NIDA)Mentored K Awardees Meeting:Making the Transition to IndependenceJuly 24 – 25, 2008
1) Lessons Learned Along the Way: Gonzalo E. Torres, Ph.D.

2) Becoming Independent With a K

3) Learning the Duties of an Independent Academic Career: 
	Teaching
	Service
	Research
	Funding
	Mentoring
	Administration

4) Life After the K:  My Own Experience and Mistakes

**1) Lessons Learned Along the Way: Gonzalo E. Torres, Ph.D.**
**2) Becoming Independent With a K**
**3) Learning the Duties of an Independent Academic Career: **
**	****Teaching**
**	****Service**
**	****Research**
**	****Funding**
**	****Mentoring**
**	****Administration**
**4) Life After the K:  My Own Experience and Mistakes**
# Presentation: 255111

## Cationic Inorganic MaterialsScott Oliver, University of California, Santa Cruz, DMR-0506279

- The goal of this project create mineral-like inorganic structures that bear a positive (cationic) charge.  These materials are templated by oppositely charged molecules (anions).  We have discovered the first examples known to date, beyond the naturally occurring clay known as hydrotalcite.
- One recent example is shown on the right.  We hope to use these open cationic materials to trap anionic pollutants such as arsenate, technetate and pharmaceuticals.

- This structure is one of the first examples of a synthetic cationic inorganic material.  Here, lead fluoride (pink and green) layers are separated by organic templating anions (red, yellow and gray).

**Notes:**
We are about to submit this paper, so I only describe the template as and organic anion on the slide.  In case the info is needed, it’s an organosulfonate.

## Cationic Inorganic MaterialsScott Oliver, University of California, Santa Cruz, DMR-0506279

- 8 graduate students, 27 undergraduates and 2 postdoctoral researcher have contributed to this project to date. Tolulope Salami, Dat Tran, Daniel Brennan, and Tedmann Onyango all graduated with their Ph.D.in Chemistry or Materials Science.  Each was first author on several publications from this project.  Many undergraduates have continued on to graduate studies in Materials.  Tran is now a postdoctoral researcher with Lara Estroff at Cornell University, Department of Materials Science and Engineering.
- Brennan received an NSF K-12 Graduate Fellowship over 4 academic years (2002 through 2006) to teach Chemistry to local Grade 3, 4 and 5 students.

- Demonstration of the TGA-MS system in the lab of the PI (back, left) to the analytical chemistry class.

**Curriculum Development**
- The PI taught analytical chemistry in Fall 2006.  This senior level course is the only analytical course offered to chemistry majors at UCSC.  The 16 students first learned the principles of TGA, DTA and DSC in lecture. A demo was then conducted of the TGA-MS system in the PI’s lab. Claudia Swanson (graduate student and one of the course TAs), describes the equipment to the students.

- Cationic Inorganic MaterialsScott Oliver, University of California, Santa Cruz, DMR-0506279

**Notes:**
I just taught this course, which focuses on instrumental methods.  I incorporated the TGA-MS into the lecture material and we demonstrated the equipment in my lab to the class, in two groups of 8.  Further development will follow when I teach the two inorganic lab courses at UCSC next academic year.
# Presentation: 667536

## Toolkit Build 66

- Toolkit Reporting Tab
- Business rules
- Uploading Contract Items to ProTracts
- ProTracts updates to Toolkit through the NCP
- Reporting Applied Amounts from ProTracts

## Report a new plan from Toolkit

- The Plan Approval Date must be in the current fiscal year.

## Report a planned practice from Toolkit for a new plan

- The Plan Approval Date (month and year) must be in the current fiscal year.
- The practice must be included in a conservation system.
- The practice must be scheduled on a land unit where a CRA, latitude and longitude have been determined.
- For digitized land units, Toolkit calculates CRA, latitude and longitude automatically.
- For tabular land units, CRA is selected from the Land Units tab, but latitude and longitude are set in PRS. The practice can be reported from Toolkit only if the map pin was set previously in PRS. If not, the practice must be reported from PRS.
- The planned *Month* and *Year* of the practice must be in the current or future fiscal year.
- The practice must not have been reported previously in PRS.

## Report a planned practice due to a plan revision

- The Plan Approval Date (month and year) is changed to the current fiscal year.
- The practice must be included in a conservation system.
- The practice must be scheduled on a land unit where a CRA, latitude and longitude have been determined.
- For digitized land units, Toolkit calculates CRA, latitude and longitude automatically.
- For tabular land units, CRA is selected from the Land Units tab, but latitude and longitude are determined by setting a map pin in PRS. The practice can be reported from Toolkit if the map pin was set previously in PRS. If not, the practice  must be reported from PRS.
- The planned *Month* and *Year* of the practice must be in the current or future fiscal year.
- The practice must not have been reported previously in PRS.

## Report an applied practice

- The *Applied Date* of the practice that was entered in the Practice Schedule must be in the current fiscal year.
*Plan Approval Date (FY)* is ignored.

## Upload Contract Items to ProTracts

- Contract items developed in the Contract Wizard may be uploaded to ProTracts.
- Contract items can be uploaded once.
- Once uploaded, contract items must be changed in ProTracts or they can be deleted in ProTracts and uploaded again from Toolkit.
- The ProTracts-generated contract number is written to the NCP.

## ProTracts Updates to NCP

- When a contract is signed and obligated in ProTracts, the obligation flag for the Toolkit is updated in the NCP.
- The contract can no longer be opened in the Toolkit Contract Wizard.
- All changes to the contract are done in ProTracts through a modification.

## Reporting Applied Practices from ProTracts

- Business issues yet to be resolved:
- Thousands of contract items are not linked to a Toolkit plan.
- Certifying an extent for one contract item in ProTracts that covers several land units in Toolkit.
- How much of the extent should be applied to each land unit?
- PRS reporting rules may need to be relaxed to allow reporting of applied amounts with no plan, land units, etc.
# Presentation: 167808

## Waterbird Conservation Council Membership Committee

## Vision of Membership Committee

- Ensures vigor of Waterbird Conservation Council
- Identifies and recruits members to Council in consultation with Council committees
- Facilitates active participation and promotes member benefits

## Objectives of Membership Committee

- Provide engaged representation of the Initiative’s breadth of geographical, taxonomic, expertise and conservation issues
- Facilitate membership participation

## Priority Tasks 2005-2006

- Complete policy and operational documents
- Develop and implement strategy for populating Council
- Promote benefits of membership

## Policy Document:  Waterbird Conservation Council—Principles of Membership

- Draft containing committee recommendations to Council available for discussion
- Seeking comments/suggestions for improvement from Council and adoption

## Principles of Membership: summary

- Initiative guidance
- Strategic composition to leverage critical conservation objectives
- Meeting the urgent needs of high priority species and habitats
- Institutionalization of  waterbird conservation in governments and ngos

## Principles of Membership: guidelines

- Governments—national representation
- NGOs—identify and recruit
- Balance areas of conservation expertise
- Build regional conservation capacity
- Strategic problem-solving

## Principles of Membership: operational

- Council size—60+?
- Committee structure; regional councils?
- Focus on organizations and individuals (no proxies)
- Renewable terms
- Optimize mutual benefits of participation

## Next Steps

- Refine, develop consensus on principles
- Draft operational documents
- Develop, promote benefits
- Prioritized list of organizations, regions, areas of expertise, etc
- Recruit
# Presentation: 909380

## Small Business Programs

- HUBZone Program
- 8(a) Business Development Program
- Womens Program
- Veterans Program
- Small Disadvantaged Business Program
- Set-aside Program

## Small Business Contracting Programs

- Certificate of Competency (COC) Program
- Size Standards Program
- Subcontracting Program (Primes)
- PRO-Net Program
- SUB-Net Program (Primes)

## Small Business Certification

- Small Business Certification Requirement
- HUBZone Program	- SBA
- 8(a) Business Development Program - SBA
- Small Disadvantaged Business Program - SBA
- Veteran Program - VA card / DD214
- Disabled Veteran Program -  VA card

## Small Business Contracting Representatives

- Procurement Center Representatives
- Commercial Marketing Representatives
- Certificate of Competency Specialists
- Size Specialists
- Business Development Specialists
- 8(a) Business Development Program
- HUBZone Empowerment Program
- Small Disadvantaged Business Program

## Small Business Contracting Representative

- Procurement Center Representatives
- 		Monitors/Evaluates Assigned Federal Agencies
- 		Reviews Small Business Coordination Record Forms
- 		DI-1886
- 		DD From 2579
- 		DOE F- 4220.2
- 		Reviews Subcontracting Plans

## Small Business Contracting Representative

- Commercial Marketing Representatives
- Monitors/Evaluates Prime Government Contractors
- Monitors Subcontracting Plans
- Provides Small Business Sources
- Monitors SF294 - Subcontracting Report Individual
- Monitors SF295 - Summary Subcontracting Report
- (www.arnet.gov)
- (Virtual Library)
- (Forms)

## Small Business Contracting Representative

- Certificate of Competency Representatives
- Evaluates Small Businesses that are low bidders
- on federal solicitation that apply for a
- Certificate of Competency (COC)
- Provide monthly status on COC’s issued to the
- Contracting Activity
- Responsible for the Small Business throughout
- the life of the awarded contract.

## Small Business Contracting Representative

- Size Specialist
- Makes determinations on Size Protests
- Small Business Set-aside
- Very Small Business
- Certificate of Competency
- 8(a) Business Development
- HUBZone
- Provides North American Industry Classification System (NAICS) information

## Small Business Contracting Representative

- 8(a) Business Development Specialist
- Partnership Agreements
- 8(a) Participants Portfolio
- 8(a) Participants Compliance & Eligibility
- Business Development Training
- HUBZone Program
- Small Disadvantaged Business Program
- Certification Verification
# Presentation: 707790

## MC generation for the B group

- Realistic MC update/remind
- Existing samples summary
- Plan: requested samples
- Developments: SAM-store and filters

## Monte Carlo samples for B-group

**Some statistics for summer production** ( > 4.10.0int3) :
- Number of official samples: 44
- Number of events simulated: 35,323,897
- No. of events produced and stored to disk: 13,087,953
- Most samples are on CAF server only fcdfdata032
- 12 bigger samples are on DFC, available via dCache.
- List available from web page
- _[http://www-](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[cdf](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[.](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[fnal](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[.](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[gov](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[/internal/physics/bottom/](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[realisticMC](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)__[/available_samples.html](http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html)_
- http://www-cdf.fnal.gov/internal/physics/bottom/realisticMC/available_samples.html
- Follow the links for full information on the sample
- Look also for the filtered samples, when available.

*All the above sample produced in Glasgow (cdfg/scotgrid)*

## Monte Carlo samples for B-group

**Structure of realistic B-MC ** :
- Step 1
- Generation (Only Pythia and Bgenerator used to now)
- Simulation with Silicon clustering
- Step 2
- Trigger Simulation TRGSim++  4.9.1hpt3
- Step 3
- svtfilter or Prereq
- Production   Use mcProduction here
- Tcl files are produced the same way as in standard MC, but number of events and run number change:
- Use script ./multirun.pl with input list of runs.
- Input: total number of events, max events per job (Filter included !)
- >= 1 job per run number
- Tar file available from fcdflnx2/scratch/dauria/jim_submit

- }cdfSim

## Monte Carlo samples for B-group

- Plan:
- Generic samples:
- At least 2 big samples requested: hadronic and l+svt details to be defined
- Inclusive samples
- J/Psi X with Pythia
- Single-channel decay:
- many samples, including charm. charm has low trigger efficiencly.

## Monte Carlo samples for B-group

- Developments:
- Smart filters required to improve efficiency
- Use SAM to store files and to make bookeeping. Tests were good. It will improve.
- Move from web page to searchable database.
- Problem report:
- QQ decayer has bad behaviour in 4.11.2 for lifetimes
- HepgFilter had limit to pdg < 10000 (excluding D1 (aka 1P10) )
# Presentation: 587709

## Adolph Link Elementary SchoolElk Grove Village, IL

- Barbara Schremser, Principal
- Katie Schneider, Teacher

- Using Data and Goal Setting to Build Classroom Communities and Improve Students’ Learning

## School Facts

- One of twenty-seven schools in Schaumburg School District 54 with kindergarten through sixth grade, located twenty-five miles west of Chicago.
- Our school serves 540 of the 14,000 students in the district.
- Our population continues to diversify, we began to question, “What can we do to ensure success for EACH student?”

## Why and How Goal Setting Works

- Why?
- Increases motivation which leads to achievement
- Enables teachers and students to track and assess progress on assessments
- How?
- Move From Concrete to Abstract
- Introduce through read aloud and discussion
- Set a classroom goal
- Have students set individual goals
- Share and reflect multiple times in a school year

**Notes:**
Explain the duration of the presentation.  Students from last year reflecting on the whole year with setting goals and clips from last year’s class.  Explain the Hand-Outs

**Notes:**
Introduction to Goal Setting – Move from concrete to abstract little piece from Board Meeting.  

**Notes:**
Classroom Goal Setting – quick points about modeling and success for all

## Slide 6

**Notes:**
Conferencing – Specific, Measurable Goals – after students work to set their goals, we check them together.  Then, they put together a power point for conferences and any tracking devices that they’ll need.

**Notes:**
Student – Led Conference Point out template in the hand-out for conference 1 and 2.  Quickly explain and state that we do twice a year.  

## Celebration and Reflection

- PEP ASSEMBLIES

- CELEBRATE LEARNING

**Notes:**
Barbara will explain how we celebrate throughout the year and at the end of the year.

**Notes:**
Overall Reflection Student Conclusions

## Learning

- Using Data and Goal Setting to Build Classroom Communities and Improve Students’ Learning

- =

- Challenges

- Challenges

- "Write it down.  Written goals have a way of
- transferring wishes into wants; can'ts into cans;
- dreams into plans; and plans into reality.
- Don't just think it - INK IT!"   -Author Unknown