BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 231009

## Penetration Depth in Organic Superconductors

- R.W. Giannetta   DMR-05-03882

- Just as ice may coexist with liquid water, electrons in what are called “strongly correlated metals”  may form coexisting phases, namely magnetism and superconductivity.   We are studying this coexistence in conductors made from the organic molecule “ET” , shown in the graph box.  Below 11.5 Kelvin, superconducting regions (shown as blue spheres) develop in the midst of a magnetic background (shown in green).  To study this mixture , we measure how far a magnetic field can penetrate into the material.   The amount is known as the London penetration depth, which is plotted in the graph below.   Here, we have varied the rate at which the material is first cooled to very low temperatures (0.5 Kelvin). It is then slowly warmed while we measure the penetration depth as a function of temperature.  Rapid cooling at 180 K/min reduces the amount of superconducting phase and makes the penetration depth increase more rapidly with temperature.  This last effect may occur because rapid cooling produces more  defects in the organic material, in turn weakening its intrinsic superconductivity.

- Magnetic phase

- Superconducting
- phase

- Organic superconductor for T < 11.5 Kelvin

## Penetration Depth in Organic Superconductors

- R.W. Giannetta   DMR-05-03882

- Education

- Two PhD students, Tyson Olheiser and Nicholai Salovich, are involved in the penetration depth measurements.   Two undergraduates (Andrew McCormick and Zane Shi) were previously involved:  Andrew McCormick is now a PhD student in physics at Harvard.  Zane Shi is now a PhD student in physics at Princeton.

- Societal Impact

- The relationship of  magnetism to superconductivity is one of the major unsolved problems in physics.  Understanding this problem will lead to new ways of controlling the passage of electrons through matter, devices with increased functionality, and insights into the design and synthesis of sophisticated new materials.   The organic conductors are a large class of materials where these problems can be studied and tested against current theories of matter.
# Presentation: 685182

## High Performance Flexible Heat Pipe

-   Reduced heat pipe weight through the development of composite 	materials, with weight reduction at least 50%
-   Received patent no. 4,917,177, cooled artery extension
**                              ****COMMERCIALIZATION**
-   Developed product line of miniature heat pipes for 			notebook computer based on sintered powdered metal wick 		technology
-   Product provides thermal management for notebook computers
-   Notebook heat pipe production rates exceed 1000/day at 		present, expected to exceed 5000/day by end of 1995

***THERMACORE INC.***
***LANCASTER, PA***

**S****mall**
**B****usiness**
**I****nnovation **
**R****esearch**

**      ****GOVERNMENT/SCIENCE APPLICATIONS**
**  **Spin-offs of composite material technology include 			lightweight tubing, tanks and valves for spacecraft
-   Spacecraft thermal controls

-  1983 Phase 2; SS-94; 10/26/95

- Johnson Space Center

**High Performance Flexible Heat Pipe**

***50 Foot Long Flexible Radiator Heat Pipe***
# Presentation: 825363

## Modeling and Visualizing Species MovementPresented at: NASA Joint Science Workshop onBiodiversity, Terrestrial Ecology, and Applied ScienceCollege Park, Maryland, August 21-25, 2006

**Funding: NASA NCC2-1186 & NCC13-03009, NSF DEB 0074444 & DEB-0413570, and NPS**

- Fred Watson1
-   Simon Cornish1
-   Bob Garrott2
-   PJ White3
-   Rick Wallen3
-   Susan Alexander1
-   Wendi Newman1
-   Thor Anderson1
-   Jon Detka1
-   Jason Bruggeman2

- 1California State University Monterey Bay
- 2Montana State University Bozeman3National Park Service

## National Park Servicebison monitoring & management activities

## A selection of productsin the pipeline

- Landscape visualization kiosk
- Canyon Visitor Education Center
- Real-time snowpack modeling
- Information that supports bison management at the boundary
- Landscape inputs to wildlife studies
- The hard science upon which policy is based
- A model for predicting species movement
- Potential contributions to any application where species move:
- biodiversity
- invasive species
- ecological forecasting
- disease vectors

## Landscape visualization kiosk

- Old visitor center

- Idea of what kiosk will look like(debuts this week in new VC)

## Real-time snowpack modeling

## Landscape model (snowpack)helps inform decision on when to release bison

- Landscape model (snowpack)helps inform decision on when to release bison

- Optimal time for release?

## Remaining 12 slides removed from web version of presentation(material in various formal submission processes)
# Presentation: 074242

## The role of variation in finding functional genetic elements

- Andy Clark – Cornell
- Dave Begun – UC Davis

## The Human Encode project

- Sequencing the regions in multiple mammals.
- Identifying genes by conservation (twinscan), by promoter signatures, etc..
- Identifying motifs by ChIP/Chip, and interspecific conservation
- Identifying motifs by phylogenetic shadowing

- Seeks to identify all functional genetic elements
- in 1% of the human genome by:

## What ENCODE won’t do

- Identify the genes that are important in determining *variation* in risk of common complex diseases.

## Low resolution of linkage methods

- Typical confidence in gene location is 10-20 Mbp.

## Equilibrium relation between LD and recombination rate

- E(*r*2)

## Linkage disequilibrium is rare beyond 100 kb or so

- 533 regions, The SNP Consortium data

## Beyond 500 kb, there is almost zero Linkage disequilibrium

## ...so observing LD means the sites are likely to be close together

- ...so observing LD means the sites are likely to be close together

## Empirical observation of linkage disequilibrium

- Reich et al. (2001 *Nature* 411:199-204)

- |D’|

- kb

**Notes:**
This is Figure 1b, showing sample size effect.  The final version would include Sweden, Yoruba, half-Yourba, quarter-Yoruba

## LD in the human genome has a “block” structure

## The HapMap project

- Genotype 2.5 million SNPs across the genome in 90 individuals from each  Europe, Asia and Africa.
- Identify regions of high and low linkage disequilibrium.
- Identify SNPs that are most informative for the neighboring regions in the genome.

*All of this is in the hope that HapMap SNPs will help to map*
*genes for complex traits by association tests.*

## HapMap woes

- HapMap is a big gamble – no model system.
- Assumes variation in risk of complex diseases is driven by a few simple, common SNPs of large effect.

## The intersection between human ENCODE and HapMap

- Resequence the ENCODE regions in 48 humans from the HapMap project.
- Genotype all SNPs discovered in all 270 HapMap individuals.
- Use the ENCODE regions to ask whether higher density HapMap would be more informative, and whether low density HapMap distorts the picture.

## ENCODE needs to have measurements of functional variation

- Not feasible in human ENCODE study.
- But it would be feasible in flies.
- The Drosophila community has a long history of innovation in studies of the genetics of complex traits.

## The role of variation in a Drosophila ENCODE project

- Nearly all functional sites will exhibit variation in sequence.
- Do they exhibit variation in function?
- Natural populations provide an important source of mutations for understanding function.

## Advantages of a Drosophila ENCODE project

**Validation** – we can do efficient experiments to test function.
- Flies have more **complex phenotypes**.
- Experimental studies are needed for the challenge of assembling **gene regulatory networks**.
- The Drosophila community is best prepared to deal with **VARIATION** at multiple levels.
# Presentation: 711476

## Attaining Greenhouse Gas Reductions at Modest and Predictable Cost

- Raymond J. KoppVice President for Programs and Senior FellowResources for the Future
- National Energy Modeling System
- Annual Energy Outlook 2001 Conference
- March 27, 2001

## A Mandatory Program

- In lieu of new voluntary measures, we propose that the U.S. initiate an early  domestic tradable permit program extending from 2002 to 2007, with three key features:
-  broad coverage,
-  modest goal with cost containment, and
-  equitable burden sharing.

## Broad Coverage = Upstream 

- To obtain the broadest possible coverage, we propose that the program be administered “upstream” at:
- Mine mouths for coal
- Well heads for natural gas
- Refinery gates for crude petroleum

## Carbon Content Permits 

- In particular, we would require raw energy producers to obtain permits equivalent to the volume of carbon dioxide eventually released by the fuels they sell.  Examples of such producers include:
- Coal processors,
- Natural gas producers, and
- Crude petroleum suppliers.

## The Target

- Issue permits for 1,347 million metric tons of carbon—roughly equivalent to 1990 annual emission levels
- Consistent with the intent of the United Nations Framework Convention on Climate Change (ratified by the U.S. Senate in October, 1992)

## Cost Containment 

- In order to prevent the program from becoming too expensive, we propose capping the price of permits.
-   Initial ceiling price of $25/ton carbon
-   Ceiling price rises by 7% (real) each year

## Equitable Burden Sharing 

- Permits are to be auctioned by the U.S. Treasury department.
- Revenues generated through permit auctions are returned to states and households.

## Equity Parameters 

- Quarterly permit auctions, with 75% of all   proceeds in the first year funding a direct   payment to all legal U.S. residents
- Remaining 25% would be given to states to address special hardships
- Reducing the share that accrues to states by 2.5% annually
# Presentation: 035518

## Spire 

- Semantic Prototypes In
- Ecoinformaics

**UMBC**
**CS**

**UMD **
**MIND SWAP**

- _[UMBC](file:///Users/js/Desktop/Spire/Virtual%20Telescopes%20in%20Education.html)_
- _[GEST](file:///Users/js/Desktop/Spire/Virtual%20Telescopes%20in%20Education.html)_

**NASA**
**GSFC**

**RMBL**
**Peace **

**UC Davis**
**ICE**

- NBII

**Semantic Web Tools**

**Agents**
**Information Retrieval**

**Education**
**Science as a Process**

**Invasive Species Forecasting System**
**Remote Sensing Data**

**Food Webs**

**Semantic CAIN**
**Ontology Development**
**Dissemination**

**Prototype applications**

- infrastructure

**Ontology of **
**Ecological **
**Interaction**

## Prototypes

- SWOOGLE
- Google for the semantic web
- Find ontologies
- Find instance data
- Study the structure of the semantic web
- Semantic CAIN
- Pond Project
- Middle school class in Vermont will study the ecosystem of their local pond with help from the semantic web.
- MINDSWAP tools (eg SMORE, Photostuff, QUIDICRC)
- http://owl.mindswap.org/downloads
- ELVIS
- Lunch of a Lunch

## ELVIS

- Species List

- Species Attributes

- Generate Food Web

- Foodweb Visualization

- Analysis

- Infer Dynamical Properties

- No data

- Distribution
- Models

- Model
- (most similar
- Species)

- No data

- data

- data

- Mapping
- Application

## Fish 1

- Fish 2

- Fish 3

- Plant 1

- Plant 2

- Plant 3

- Taxonomic Neighbors

- Taxonomic Neighbors

- Lunch of a Lunch
- We know Fish 1 eats Plant 1. We infer that Fish 1 may also eat the taxonomic siblings of Plant 1: Plants 2 and 3. Similarly, we infer that the taxonomic siblings of Fish 1 - Fishes 2 and 3 - may eat Plant 1.

## Semantic ISFS

- Add trophic data to mining runs
- Publish ISDS in RDF/OWL
- Open Database Initiative
- ISAMS as a semantic web service
- Electronic field forms
- Annotation services
# Presentation: 316560

## Proper motion surveysand theGalactic dark matter

- Bertrand Goldman
- N.M.S.U. – N.A.S.A./Ames

## Summary

- White dwarfs contribution to the Galactic halo
- Constraints from proper motion surveys	(EROS 2 proper motion survey)
- Some positive results
- SNAP surveys
- Halo white dwarfs
- Brown dwarfs

## Why white dwarfs?

- Microlensing results towards the Magellanic Clouds
- MACHO positive signal: 20%, ≈0.5 Mo

- Alcock et al, 2001

- EROS 20% upper limits

- Various indirect constraints
- C and N pollution (Brook et al. 2003)
- D and He pollution (Fields et al. 2000)
- TeV rays surviving the progenitors’ redshifted light		(Graff et al. 2000)

## Why not white dwarfs?

- No strong direct constraints:
- HWD LF depends on cooling function, WD mass and progenitors’ IMF(bias toward high masses makes WD cooler)
- Liebert et al, 1998

- Chabrier, 1999

- disk WD LF

*v**tan *>250km/sWD LF

## EROS 2 proper motion survey

- Uses the EROS 2two-broad band,wide-field imager1o2, 2x 32 Mpix

- 250o 2 over five years,mid and high Galactic latitudes
- Data shared with the nearby SNe search program

## EROS 2 proper motion surveyresults

- no candidate	 95% CL limits
- Color-dependent when combining both bands
-   7% for *M**V *=17 to30% for *M**V *=18
- if 5+% DA WDs,  age > 14 Gyr

- Goldman et al, 2002

## Other proper motion surveys

- Several other failed to detect halo WDs
- Knox et al, 1999 (stacked plates)
- Crézé et al, 2004 (CFHT 12k)
- Other reported halo white dwarf discoveries:
- Ibata et al, 2001: ≈10% (2 confirmed fast, cool WDs 					in survey plates)
- Oppenheimer et al. 2001 (and Salim et al. 2003): 			1–2% of the halouncertainties on the nature of those objects:young (Hansen, 2001); thick disk dynamics and contamination (Reylé et al, Reid et al, Flynn et al, 2001)

## SNAP contribution

- Detection of 14 Gyr white dwarfs, in most bands, high above the Galactic plan:1,500 pc with proper motion (deep fields)3,000 pc by color, flattening measurementthousands of WDs if halo is made of 1% WDs
- WD LF of the thick disk to the end 	with height distribution
- LSST will also solve these questions
*Using the Chabrier et al, 1999 cooling functions*

## Brown dwarfs

- 8 detection in two or more bands of *T**eff *= 300 K BDs (9 MJ @ 5 Gyr, or 4 MJ @ 1 Gyr)     375 pc3 with proper motion and parallaxes   6,000 pc3 with the deep field surveys12,500 pc3 with a 500o2 wide field survey
- Detection of *T**eff *= 220K planets 	(5 MJ @ 5 Gyr, or 2 MJ @ 1 Gyr) in the deep surveys up to 15pc (5pc3)
*Using the Baraffe et al, 2003 models*
- WISE would do better
# Presentation: 202177

## THE ADR PROCESS~~~~~~~~~~KEY ISSUES AND ELEMENTS

**PRESENTED BY:**
**Anthony N. Palladino**
**Associate Chief Counsel and Director**
**FAA Office of Dispute Resolution**
** ****for Acquisition**
**May 19, 1999**

## DECIDING WHETHER TO USE ADR IN YOUR CASE

**DIFFERING  VIEWS ON ADR USAGE**
**APPLYING CASE SCREENING CRITERIA**
**The ADRA of 1996**
**DoJ Guidelines**

## CHOOSING A FORM OF ADR

**THE RANGE OF ADR OPTIONS**
**BINDING V. NON-BINDING**
**FACILITATIVE MEDIATION**
**NEUTRAL EVALUATION**

## THE ROLE OF LEGAL COUNSEL IN ADR

**DECISIONMAKING AUTHORITY RETAINED BY**** ****CONTRACT MANAGER OR IPT**
**COUNSEL PROVIDES GUIDANCE ON: **
**LEGALITY**
**LITIGATIVE RISK**
**PRESENTATION ISSUES**
**SETTLEMENT AGREEMENTS **

## NEGOTIATING AN ADR AGREEMENT

**WRITTEN AGREEMENT DESIRABLE**
**AGREEMENT SHOULD INCLUDE:**
**SPECIFIC ADR PROCEDURE**
**SCHEDULE**
**SELECTION & COMPENSATION OF NEUTRAL**
**AVAILABLE SAMPLE AGREEMENTS**

## CONFIDENTIALITY 

**A KEY ADR CONSIDERATION**
**ADR AGREEMENT MUST COVER**
**USE  IN LITIGATION **

## CHOOSING AN ADR NEUTRAL

**CONSIDERATIONS:**
**REPUTATION**
**ADR EXPERIENCE**
**SUBSTANTIVE KNOWLEDGE**
**IN-HOUSE OR OUTSIDE NUETRALS**
**BCA JUDGES**

## PREPARING FOR ADR

**DEVELOP FACTUAL & LEGAL ISSUES**
**DOCUMENT EXCHANGES & DISCOVERY**
**PREPARE POSITION STATEMENTS**
**DESIGNATE PRINCIPAL **

## DECIDING TO SETTLE

**RISK ASSESSMENT ESSENTIAL**
**EVALUATE COSTS & BENEFITS**
**CONSIDER:**
**RELATIVE STRENGTHS & WEAKNESSES**
**COSTS TO PROGRAM **
**EFFECTS ON RELATIONSHIP**
**BENEFITS OF SETTLEMENT**

## MEMORIALIZING THE SETTLEMENT

**REQUIRE A WRITTEN AGREEMENT**
**SIGN PRELIMINARY BEFORE LEAVING THE ADR SESSION**
**ADAPT AVAILABLE FORM AGREEMENTS**
**SIGNATORIES WITH AUTHORITY**

## MEASURING SUCCESS

**VARIOUS METHODS AVAILABLE**
**COMPARE  TO RISK ANALYSIS**
** ****COMPARE SETTLEMENT TO CLAIM**
**COMPUTE SAVINGS COMPARED TO :**
**FURTHER LITIGATION COSTS & TIME**
**NEGATIVE IMPACT OF CONTINUED LIT. ON PROGRAM OR OTHER WORK**
# Presentation: 534676

## Effects of fetal exposure to isoflurane on 

**postnatal memory and learning in rats **
**Huafeng Wei, MD, PhD**
**Assistant Professor**
**Department of Anesthesiology and Critical Care**
**University of Pennsylvania**

## Financial Disclosure

**Grant Support:**
**March of Dimes Birth Defect Foundation **
**( #12-FY05-62)**
**NIH NIGMS K08 073224-02**
**Department of Anesthesiology and**
**Critical Care at University of Pennsylvania**
**E+D fund**

## Is Isoflurane Neurotoxic to Fetus Developing Brain?

**Isoflurane induced apoptosis dose-and time-dependently in different neuronal cultures. **
**Isoflurane induced apoptosis in the developing brains of 7-day-old rat pups and subsequent memory and learning disability. **
**Isoflurane caused permanent memory loss, learning disability in aged rats.**
**Hypothesis: Isoflurane inhaled to pregnant mothers induced apoptosis in fetus developing brain and postnatal memory and learning disability.**

## 1.3% Isoflurane Inhibited Apoptosis in Fetus Hippocampus CA1 and Retrosplenial Cortex

**Caspase-3 Density**

**Hippocampus CA1**

**Retrosplenial Cortex**

## Isoflurane Improved Spatial Reference Memory In Juvenile But Not Adult Rats

**Probe Test, * Means P<0.05**

## Summary 

**1.3% isoflurane for 6 hour in pregnant rats inhibited spontaneous apoptosis in fetus brain at 2 hour, but not at 18 hour or postnatal day 5 after treatment.**
**1.3% isoflurane for 6 hour in pregnant rats improved spatial reference memory in postnatal juvenile rats (P36), but not in adult rats (P119). **
**1.3% isoflurane for 6 hour in pregnant rats did not affect learning in postnatal rats.**

## Acknowledgement 

_**University of Pennsylvania**_
**	****	****Grace Liang, Yujuan Li, Shouping Wang,**** ****Qiujun Wang, Wenlin Wei, Baobin Kang, Qing Cheng Meng **
**	****	**
**	****	****Roderic Eckenhoff, Randy Pittman, Maryellen Eckenhoff**

*rodent memory, learning and behavior.*

**Cued test (Swimming ability, P28)**

**  ****Place test (Learning and memory, P32, P115)**

**Probe test (Memory, P36, P120)**

**	**
# Presentation: 691703

## NIH/NASA Meeting onSpace-Related Health Research

**NIH/NASA Meeting on****Space-Related Health Research**

**Henry Rodriguez, Ph.D., M.B.A.**
**Director, Clinical Proteomic Technologies Initiative**
**National Cancer Institute**

**December 8, 2006**

## Technology Benefits

- Bio-Technology Benefits to NASA

- Technology Benefits to NCI

**Miniaturized biochemical analytic laboratories**

**Bio-Astronautics and Human Exploration**

**Fabrication of ultra rugged materials and structures**

**Early detection**

**Accurate diagnosis**

**Prevention and improved therapies**

## Fundamental Technologies in Biomolecular Sensors (NCI-NASA)

- Workshop (June 1999) on Sensors for Bio-Molecular Signatures
- Richard Klausner, *Director NCI*;  Daniel Goldin, *NASA Administrator*
- April 2000 MOU, Oct. 2000 launched
- Total 6 awards, $13.6M over 4 yrs.
- Launching companies & Building foundation for NCI Alliance for Nanotechnology in Cancer
- Peptide Functionalized Nanoparticles (Alnis Biosciences Inc., collaboration with UNC Center of Cancer Nanotechnology Excellence)
- Ultra-bright Near Infrared Fluorophores (possible synergy with Emory and MIT/Harvard Centers of Cancer Nanotechnology Excellence)
- Molecular Beacons (PI became co-PI of MIT/Harvard Center of Cancer Nanotechnology Excellence)

**Nanogel**
**(carbohydrate or PEG nanoparticle**
**– ****targeted drug delivery tool)**

**A**

**B**

**C**

## Object Oriented Data Technology(NCI-NASA/JPL)

**Object Oriented Data Technology****(NCI-NASA/JPL)**

- OODT’s architecture originally developed for NASA’s planetary data system (PDS) project by JPL
- Open source & Based on open standards: Java, XML, Web Services
- Distributed network that is secure and confidential
- EDRN’s Virtual Specimen distributed query system (ERNE) is based on NASA’s OODT
- Existing sites specimen databases maintained locally
- Uses EDRN Common Data Elements (CDEs)
- OODT Framework includes:
- Name Server; Query Server; Archive Server; Profile Server; Product Server; Server Manager

## Nanowire arrays for early detection (NCI/NASA-Goddard/U. Maryland)

**Nanowire arrays for early detection (NCI/NASA-Goddard/U. Maryland)**

- Controlled on-chip synthesis (SiNWs and carbon nanotubes)
- Surface mod. readily achieved for affinity-capture material
- Ultra-sensitive and fast sensors for electrical, real-time and label-free detection sensing of chemical or biological species (amplicon - femtomolar)
- Nucleic acid sequence detection, protein marker detection, and single viral particle detection

*Nanomedicine (2006) 1(1), 51-65*

*Nature Protocols (2006) 1(4), 1711-1724*
# Presentation: 360560

## ENERGY CONSERVATION

**Louisiana Office of **
**State Fire Marshal, Code Enforcement, and Building Safety**
**Henry C. Reed, Sr.**** **
**Architect Supervisor**
**1-800-256-5452 **

## ENFORCEMENT OF THE ENERGY CODE  

**WHO WOULD ENFORCE**
**HOW TO ENFORCE **
**WHAT TO ENFORCE **
**WHEN TO ENFORCE**

## WHO WOULD ENFORCE THE LAW 

**Office of State Fire Marshal**
**Code Compliance Managers (C.C.M.’s)**
**Increase Number of C.C.M. Staff  **
**No On-Site Inspections**
**Attorneys**

## HOW TO ENFORCE THE LAW

**Additional Training for C.C.M.’s**
**Additional Equipment (desks & computers)**
**Additional Compliance Management Procedures and Policies**
**Additional Forms and Standard Letter Templets**

## WHAT  LAW  / RULE TO ENFORCE

**All Buildings Over 100 Square Feet **
**Buildings Required by State Law to be Constructed by Architects and Engineers**
**All Buildings Over 1,000 Sq. Ft. (90% of all new buildings)**

## WHEN TO ENFORCE THE LAW

**January 1, 1998 - $20 Fee Increase**
**July 1, 1998 - Voluntary Examinations**
**January 1, 1999 - Mandatory Compliance For Architects and Engineers **
**January 1, 2001 - ALL Buildings in Excess of 1,000 Square Feet (except certain storage & industrial buildings)**

## Non-exempt New Buildings Fiscal Year 1999/2000

**2nd Quarter Total****	****Projected  850****	****Actual       915**
**3rd Quarter Total****	****Projected 1275****	****Actual      1310**

## Louisiana’s Energy Strategy 

- Realistic Exemptions
- Professional’s Liability
- Owner’s Liability
- Phased Implementation
- Professional Threshold
- Small Buildings Submitted By Owners
# Presentation: 877401

- (Trying to have)
- Fun at the Supercomputing 2006

## Layout

- Open flow
- Cheap
- Flexible
- Easy to assemble/present/disassemble
- SLAC is responsible/will come up with, but it is good to have an opinion/alternatives

## Content

- Theme: ‘(Postcards from?) the Quantum Universe’
- Keywords: Einstein, Powerful, Beyond Imagination, (Quantum) Universe, Discovery, Colliders
- Non-scietific audience  Minimum of words, maximum of images
- Dynamic images rather than static (_short_) movies/slideshows/presentations (image rich)
- Whenever possible: expose the role of computing and computers

## Hardware/equipment

- 7 display segments:
- 4 plasma (LCD?) screens
- 3 posters
- 4 projection screens
- 2 interactive workstations

## Static posters

- Questions for (about?) the Universe
- Einstein’s dream of unified forces
- The particle world
- Birth of the Universe

## Presentations/slide shows

- Experiments and Detectors
- World Wide Web of Laboratories (FNAL/SLAC/CERN/KEK/DESY)
- Images of the universe
- Faces of Fermilab
- Hadron Colliders
- Arts and Physics
-  Tracking down particles
- Oddone’s talk for summer students (abbreviated)

## Movies

- SDSS  (3D?)
- The CMS quest
- Atlas detector
- LHC machine
- MINOS experiment
- Gravity waves
- Gravitational lensing
- Black hole
- Powers of ten

## Movies (the lighter side)

- NOVA: The Elegant Universe
- The Quantum Café
- Extra Dimensions?
- LHC (Les Horribles Cernettes)
- Quantum Universe by Fermi Singers (?)

## Interactive displays/activities

- Cloud chamber
- Silicon chip probe station
- Hitting the beams head-on (?)
- E-mailing postcards from the Quantum Universe
- Live video link to CDF/MINOS control rooms and to some selected physicists

## Handouts

- Quantum Universe
- Discovering the Quantum Universe
- Bluff your way in the  Quantum Universe
- Pieces of scintillator
- Pieces of scintillating/waveshifting fibers
- ILC Handouts
- Neutrino Handouts
# Presentation: 054643

## The Case for Component Reconnection

- Indicators
- Reconnection in subsolar region for most Bz.
- Reconnection poleward of the cusp near NBz.
- Ionospheric leakage suggests subsolar even for NBz.
- Extent of the X-line is inferred to be 4-5 Re.
- An anti-parallel X-line has little extent.
- X-line integrates to an S or Z shape, looping cusps.
- Sunward sub-solar plasma flows inside magnetopause.
- Objections:
- Non-reconnecting field magnetizes electrons, inhibits rate.
- Counterpoint: “guide” field does not obstruct current flow.
- Counterpoint: 3D PIC simulations support this assertion.

## Component vs Antiparallel Reconnexion

- Crooker, 1979; Luhmann, 1984

- Cowley 1976; Moore, 2000 AGU SM

## Component Reconnection

- Observations
- Gosling et al., 1990 JGR.
- Chandler et al. 1999 JGR (sub-cusp even for NBz)
- Scudder et al. 2002 JGR in press (large, stable region)
- Mozer et al., 2002 PRL (near antiparallel, near equator)
- Khan et al. 2002 GRL
- Chandler and Avanov, 2002 (in review)
- Theory
- Gonzalez and Mozer, 1974 JGR.
- Cowley and Owen, 1989 PSS.
- Shay et al., 2001 JGR; Pritchett, 2001 JGR.
- also Drake, Rogers, Shay AGU presentations)
- Moore et al., 2002 JGR in press
- DOI 10.1029/2002JA009381

## X-line Integrates to S or Z Loop

- Antiparallel Sites

- Component X-Line

## Open Flux Tube Motion at M’pause

- Cowley and Owen [PSS 1989]
- Assume SH and BL fields are equal in magnitude
- (MP as rotational discontinuity)
- Plasma flows across boundary freely:
- pressure balance established inward of BL, where SH plasma drops in pressure and MS field increases.
- Assume HT frame where
- Vplasma // BSH, in SH
- Vplasma = VHT, at MP
- Vplasma // BBL, in BL
- Geometric Construction:
- Flux tube motion at MP (HT)
- Plasma motion in SH, BL
- Results along straight X-line

- VBL

- BSH

- BBL

- Earth

- HT

- VSH

- VHT

- VSH=VAbSH

- VBL=VAbBL

- Velocity Space Diagram

## Subsolar Sunward Plasma Flows 

- 03/20/01

- 04/02/02

- Vz

- Vy

- Vx

- Vx

- GSE

- Sun

## Conclusion

- Component reconnection certainly exists.
- Along an integrable X-line, rate will vary with local conditions.
- Rate may vanish only for exactly parallel fields.
- Subsolar limiting rate ≥ high latitude rate except exact NBz
- Carried to the low shear extreme:
- Do slightly sheared auroral flux tubes reconnect?
- Produce spiral flux tubes wrapped around currents?
- Diffusion of auroral shear significant as viscosity?
- Smooth transition to high shear case.
- Anti-parallel sites tend to have largest rates, potential energy
- Hypothesis: begins at or near anti-parallel sites and spreads
- Actions:
- Cluster investigations map X-line orientation
- Global simulations map X-lines
# Presentation: 394183

## 2007 Commodity Flow Survey Purpose, Uses & Products Joy SharpAssistant Director for Survey ProgramsBureau of Transportation Statistics

**Talking Freight Seminar**
**December 10, 2008**

## CFS Purpose

- The CFS provides a comprehensive multi – modal picture of national freight flows, and represents the only available source of data for the highway mode that carries about 75 percent of the value and 70 percent of the tonnage of freight transported.

## Survey Results (2002 CFS)

**Survey Results (2002 CFS)**

- On a typical day, about 43 million tons of goods, valued at about $29 billion, moved nearly 12 billion ton-miles on the nation's transportation network.
- Trucking continues to dominate the freight industry in value and weight, accounting for nearly 3⁄4 of all freight transported.
- Approximately 19% (by weight) of all goods shipped in were classified as hazardous materials.

## Data Uses

- analyzing trends in goods movement over time;
- conducting national, regional and sectoral economic analysis;
- developing models and analytical tools for policy analyses, management and investment decisions;
- forecasting future demand for goods movement and associated infrastructure and equipment needs;
- establishing benchmarks for estimating national accounts; and
- analyzing and mapping spatial patterns of commodity and vehicle flows.

## Major Differences: 2002 to 2007 

**Major Differences: ****2002 to 2007**** **

- Scope and Coverage
- Forms and Content
- Sample Size and Design
- Processing
- Data Products

## CFS Data Products

**CFS Data Products**

**Preliminary Data Release - Dec. 9th**
-  6 National-level Tables: Mode, Total Modal Activity, Distance, Weight, & Commodity
-  New for 2007:  Industry Tables
-  Shipment Characteristics (value, tons, ton-miles, and ave. miles)
-  Available on BTS and Census websites
-  Cautionary Note

## Table 1 

## Table 2

## Table 3

## Table 4

## Table 5

## Table 6

## Final Data Release 

**Final Data Release**** **

**Final Data Release – December 2009**
- National, State, MSA
- O-D Flow Tables
- Hazmat & Export
- 3PL Providers
- Web and Print Publications

## More information

- BTS Website:
- _[http://www.bts.gov/publications/commodity_flow_survey/](http://www.bts.gov/publications/commodity_flow_survey/preliminary_tables_december_2008/index.html)_
- _[preliminary_tables_december_2008/index.html](http://www.bts.gov/publications/commodity_flow_survey/preliminary_tables_december_2008/index.html)_
- Census Website:
- _[http://factfinder.census.gov/servlet/DatasetMainPageServlet](http://factfinder.census.gov/servlet/DatasetMainPageServlet_program=ECN&_submenuId=datasets_4&_lang=en)_
- _[_program=ECN&_submenuId=datasets_4&_lang=en](http://factfinder.census.gov/servlet/DatasetMainPageServlet_program=ECN&_submenuId=datasets_4&_lang=en)_

## Contact Information

- Joy Sharp
- _[joy.sharp@dot.gov](mailto:joy.sharp@dot.gov)_
- (202) 366-0881
# Presentation: 704168

## PROTEIN EXPRESSION LABORATORY

- Jim Hartley, Director
- “Helping you get the proteins you need.”
- SAIC / NCI Frederick
- Research Technology Program
- Joe Kates, Director

## PROTEIN EXPRESSION LABORATORY

- Cloning

- Expression Optimization

- Eukaryotic Cell Production

- Microbial Fermentation

- Protein Purification

- _Complete pathway or any step_

- In vitro
- transcription/
- translation

## Cloning and Expression Optimization

- Dominic Esposito, Group Leader
- _Cloning_
- PCR      Gateway      Sequencing
- Restriction enzymes and ligase
- Multiple expression vectors (>50)
- _Expression optimization (E. coli)_
- Strains
- Temperature
- Fusion tags
- Induction time, level

## Expression optimization:

- E. coli strain (rare codons)

## Expression optimization:

- Temperature after induction

## Expression optimization:

- Fusion tags

## Expression optimization:

- Fusion tags and solubility

## Microbial Fermentation

- David Miller, Group Leader
- E. coli, yeast
- Shake flasks to 60 liters
- Batch and fed batch
- Cell lysis and processing (membranes)
- Isotopic labeling

## Microbial Fermentation:

- _Microbial Fermentation:_
-  Computer controlled 80
- liter fermenter, working
- volume 20 – 60 liters
-  4 x 20 liter fermenters,
- computer controlled, 5 –
- 15 liter working volumes

## Microbial Fermentation:

- Batch (tank) vs. fed batch

## Eukaryotic Cell Production

- Butch Hopkins, Group Leader
- Mammalian and insect cell culture
- Transfections
- Transient and stable expression
- Baculovirus amplification, titer
- Antibody production

## Eukaryotic Cell Production: high efficiency production of monoclonal antibodies

## Transfection of insect cells with GFP baculovirus

## Protein Purification

- William Gillette, Group Leader
- Native and affinity purification
- Microgram to gram scale
- Refolding

## Protein Purification Group:

- His6-tagged protein,
- overexpressed in E. coli

## Protein Purification Group:

- Lower expression in
- E. coli, His6-tagged

## In Vitro Transcription / Translation

- Deb Chatterjee, Group Leader (July 2002)
- E. coli lysates
- T7 RNA pol
- PCR products or plasmids
- High productivity
- Affinity purification
- Avoids toxicity

## PEL: Future

- New expression systems per requests
- Hosts
- Vectors
- IVT
- Membrane proteins
- Insoluble proteins
- Highly parallel testing of many expression states

## Slide 19

## Protein Expression Laboratory 

- SAIC / NCI Frederick
- Jim Hartley, Director
- Dominic Esposito, Cloning and Expression Optimization
- David Miller, Microbial Fermentation
- Butch Hopkins, Eukaryotic Cell Production
- William Gillette, Protein Purification
- Deb Chatterjee, In Vitro Transcription / Translation
# Presentation: 337065

## International Space Station Procurement Office

**ISS Procurement Office**
**Gail Skowron, Manager**
- Katherine Autry, Deputy Manager
- Tracy Quintanilla, Secretary (*RCJV*)

**       **
**MTLO Bus. Mgr. (OK111)**
- 	Lisa Munday

**ISS Sustaining**
**Procurement Team**
- John Trahan, Lead

**ISS Program Integration and Operations Procurement Team**
- Michelle Isermann, Lead

*Mod Manager*
*Anne Greer (Anadarko)*

- Michele Ladrach, CS

- Lee Ann Audet, CO Limited

- Yaranet Marquez (out)

- Marianne Ruiz, CO

**International Space Station Procurement Office**

- Renee Falls, CO

- Carol Neeley, CO

- Bermuda Brittingham, CS

- Lauren Johnson, CS

- Eric Schell, CO

- 5/14/08

- Rob Chapman, CO

- Carolyn Flure, Anadarko
- New DCMA (in)

- Stephanie Hunter, CO

- Jenny Arkinson, CS

- Darrell Johnson, DCMA

- Craig Burridge, CO (out)
-  Judy Ross (CO) (in)

- Sheela Logan, CS

- Kelly Jennings, CS

- Danielle Ross, (Intern)

- LaToy White, CS (out)
- Kirby Condron (in)

- Vacant, coop
# Presentation: 667862

## Week of September 9 to September 16 D0 Summary

- Delivered luminosity and operating efficiency
- Delivered: 4.0pb-1
- Recorded: 2.7pb-1 (~68%)
- Data taking efficiency
- no major hardware/software problems
- New records over last week
- global run efficiency 92% (up from 85%)
- daily operating efficiency 87% (up from 75%)
- weekly operating efficiency 68% (up from 65%)
- Issues caused 1+ hours downtime
- Silicon readout and HV trips issues
- CFT readout and downlaads
- Loss of SCL signals for L1 calorimeter crate
- Muon PDT failure
- Accelerator halo
- reasonable
-  Beam position
- stable within 0.3mm from the detector center

- Dmitri Denisov

## D0 Detectors Status

- Luminosity detector
- Stable operation
- Estimated luminosity measurement error is 10%
- Silicon detector
- Power supplies are running well - no problems for 3+ months
- Noises stable: ~94% of channels are in operation
- Fiber tracker
- Stable operation with all channels in readout
- Major issue is  hot/empty groups of channels
- in progress of studying this issue
- Calorimeter
- Stable
- Different sources of low energy noises are under investigation
- Muon
- Stable operation
- Major issue is “data integrity”
- on the 10-3-10-4 level there is data format corruption
- Forward proton detector
- inserting pots during most stores

- Dmitri Denisov

## He Concentration in the Hall

- After multiple improvements He concentration in the collision hall is stable on the 10-20ppm level
- We can even “detect” Tevatron quenches in the vicinity of D0

- Dmitri Denisov

## Data Taking and Triggering

- Running smoothly physics trigger list 8.2
- stable over last 3 weeks
- designed for luminosity in the range (5-25)1030
- keeping high pt triggers un-prescaled at any luminosity
- efficiency of top detection is ~90+%
- Typical trigger rates
- L1 trigger 0.3kHz
- L2 trigger 0.15kHz
- L3 trigger (to tape) ~50 Hz
- Total number of events collected over last week
- 7.5 mln
- Reco reconstruction speed is improved in reco version 11.11
- processing about 4 mln events per week
- new nodes for the D0 farm are at Fermilab and burn in is in progress

- Dmitri Denisov

## Summary

- D0 experiment is progressing well with physics data taking
- no major problems with detectors/electronics/triggers/DAQ
- all detectors are in readout
- trigger list 8.20 is running on-line
- Data taking efficiency is ~68% over a week, ~87% over a “good” day, and ~92% for a “good” run
- multiple items designed to improve D0 operating efficiency are starting to pay off
- voice instructions to shift crew
- automatic crates restart after crash
- etc.
- record daily downtime is reduced from 25% to 13% - almost factor of 2

- Dmitri Denisov
# Presentation: 182754

## Collaboration prospects on 325MHz front end 

-  Most promising is RFQ – J-PARC design is almost exactly what we need.
-  Possibility of copying JPARC DTL, SDTL.
-  Chopper, bunchers, diagnostics for MEBT also of interest
- With ANL
-  Linac low energy end – RT resonators, focusing, beam dynamic simulation,
-   finally baseline design and options.
-  Single, double and triple spoke SCRF resonators. Cavity designs go first, beam
-   dynamic iteration with RT part, optimization, finally baseline lattice.
-  Next-generation test cryostat for spoke resonators (for both SMTF & RIA/ANL)
- NIU (Court Bohn et al.) seems to be enthusiastic about helping out with anything
- 	that gets 325 MHz beam going in SMTF ASAP.  Have access to non-DoE
- 	funding sources for collaborations with ANL and FNAL.
- Other SMTF collaborators including MSU on 1300 beta<1 cavities, simulations,...

- _Collaboration prospects on 325MHz front end_

- _Possible Areas of the collaboration include:_

- Gennady Romanov

- October 12, 2004

## RFQ  design parameters

- _RFQ  design parameters_

- SNS

- J-PARC

- J-PARC is closer to our requirements

- Gennady Romanov

- October 12, 2004

## Contact persons & possible Collaboration Projectsat KEK / JPARC

- Ioshi Yamazaki
- Akira Ueno (RFQ)
- Fujio Naito (DTL, SDTL)

- Gennady Romanov

- October 12, 2004

## We asked KEK for technical documentation

- including RFQ drawings. We might
- just correct them if needed, place an order
- in industry and save a lot of time and effort.
- KEK plans to replace their 30mA RFQ with a
- new 50 mA design.  Their future plans for the
- 30 mA RFQ are unknown. Might it be possible
- to re-tune it from 324 MHz to 325 MHz?

- Gennady Romanov

- October 12, 2004

## Contact persons & possible Projects at ANL

- Peter Ostroumov ( general accelerator physics, beam dynamic simulation.
- Ken Shepard ( SC accelerating resonators)
- Ken will be supervising a graduate student from University of Illinois / Urbana Champaign who will be doing his thesis on pulsed-mode operation of RIA-type resonators as they would be used for Proton Driver.
- Joel Fuerst (cryogenics)
- FNAL & ANL are interested in co-producing two copies of a next-generation test cryostat for spoke resonators.  (one for Meson Lab, one for ANL/RIA)

- Gennady Romanov

- October 12, 2004

## Front end based on DTL

- SSR      3-28 Mev	16 m	2 cryostat	1.6 MeV/m				         **Base**
**DTL      3-36 MeV****	****18 m****	****2 tanks****	****1.83 MeV/m    two klystrons (****for 50 mA****)                              Proposal**
- 					               = 0.27, DSC ->   = 0.4

- 27 m

- DSR, TSR, Tesla1, Tesla

- J-PARC
- lattice

- _Front end based on DTL_

- SSR, DSR, TSR, Tesla1, Tesla

- or

- Gennady Romanov

- October 12, 2004

## Front end based on individual RT resonators

- _Front end based on individual RT resonators_

- P.N.Ostroumov.

- Focusing by SC
- solenoids in indi-
- vidual cryostats.

- CH-cavity – possible candidate

- Gennady Romanov

- October 12, 2004
# Presentation: 366183

## Boston Public SchoolsHigh School RenewalMay 2004

- Boston Public SchoolsHigh School RenewalMay 2004

**Archived Information**

## High School Renewal 

- High School Renewal

-  Major focus area for the past four years
-  High schools slower to improve than other levels
-  Grants from Carnegie, Gates to improve high schools
-  Support in high schools for improved teaching - literacy, coaches, Workshops
-  New structural approaches needed

## Why small high schools?

- Increased sense of belonging for students and staff
- High expectations for students and work
- a culture of depth over breadth and on-going self-reflection
- student-centered instruction and inquiry-based learning
- on-going self-assessment by students and teachers
- school climate that supports a professional learning community for adults and an engaging learning environment for students
- increased parental involvement and community collaboration
- locally generated professional development correlated to capacity-building and improved instruction

## Lessons learned 

- When small high schools are:
- teacher-designed
- have more control over budget, time, curriculum, staffing and instruction
- the differences in student achievement can be significant.

## Lessons Learned (cont.)

- Small schools can be an effective strategy for improvement of large high schools.
- Small learning communities can result in more personalization and improved instruction - if they are not layered onto a comprehensive school framework.
- Community involvement is an essential component of high school renewal.

## New high school policy for Boston

- District high schools will divide into small schools or small learning communities
- Small schools or small learning communities will all be grade 9-12
- Six new high schools will be created at West Roxbury and Hyde Park Highs
-  A new Policy for Ungraded High Schools is now being considered

## Challenges 

- Continuing the scale-up of teaching and learning for all students to get all students to proficiency and narrow the achievement gaps
- Aligning central office support and resources
- Developing interventions for over-age and other youth at risk of not graduating
- Engaging more students in the reform effort
- Building community support and demand for high school renewal

## Importance of Partnerships

- New partnerships - with families, community-based organizations, and businesses - focused on smaller schools
- Partnerships at all levels closely aligned to learning priorities and themes in schools
- Emphasis in partnerships of bringing students into workplaces and bringing community into schools
# Presentation: 215427

## Clinical Bioinformatics Ontology (CBO) 

- Maki Moussavi, M.S.
- Genomics strategist

## The Clinical Bioinformatics Ontology (CBO)

- Cerner Initiated
- The Clinical Bioinformatics Ontology (CBO) is a semantically structured controlled vocabulary for clinical molecular diagnostics.
- The CBO addresses the need for consistent descriptions and representations of molecular biological and cytogenetic entities currently performed in clinical diagnostics in a standardized and machine readable format.

## The Clinical Bioinformatics Ontology (CBO)

- CBO combines the attributes of a controlled vocabulary by providing standardized naming conventions and coded values.
- The CBO provides a set of concepts that share complex relationships that provide biological context.
- Combines attributes of a medical vocabulary with positional information offered by bioinformatics resources.
- The CBO focuses on gaps in existing clinical vocabularies (SNOMED-CT®, LOINC®) to meet the needs of clinical molecular diagnostics and cytogenetics.

## Controlled Medical Terminology (CMT) TM

- The Cerner Controlled Medical Terminology (CMT)TM is a meta-vocabulary associating most of the common medical vocabularies, including SNOMED and LOINC. CMT enables integration of concept-based capabilities into the Cerner Millennium® suite of clinical software.
- The CBO was designed to reflect a structure similar to that of SNOMEDCT in order to favor compatibility with the phenotypic information that is codified in clinical information systems. Hierarchical relationships were combined with lateral definitional relationships to create the semantic network.
# Presentation: 291697

## scarlet globemallow Sphaeralcea  coccinea (Nutt.) Rydb. Other common names; red false mallow, false mallow, common globemallow, scarlet globemallow, prairie mallow, desert mallow, flame mallow, copper mallow, cowboy’s delight.

**Medicinally:**
- A poultice was applied to burns, scalds and sores as a cooling agent.  This paste was also applied to the outer skin of hands and arms so they would be protected when put into very hot water.
- A dried root powder or a root lotion was applied to skin lesions.
- When made into a tea it is used as a beverage, and as a way to sweeten other medicines.
- It was used as a tonic to improve appetite, cure rabies, for joint swellings or pain and by pregnant women.
**Culturally**:
- This plant is used as a ceremonial fumigant and when drank is to thought to give a singer greater strength.

- Photo courtesy of:  Margaret Williams. Courtesy of _[Nevada Native Plant Society](http://heritage.nv.gov/nnps.htm)_. ©Nevada Native Plant Society. This copyrighted image may be freely used for any non-commercial purpose. For commercial use please contact _[Gary A. Monroe](mailto:gmonroe@softcom.net)_.   Please credit the artist, original publication if applicable, and the USDA-NRCS PLANTS Database. The following format is suggested and will be appreciated:   **Margaret Williams** @ USDA-NRCS PLANTS Database.

- Slide developed by Pat Broyles, Soil Conservationist, Manhattan, KS. PMC.  USDA is an equal opportunity employer.
# Presentation: 772584

## IGS, Regional and Local Networks

**IGS, Regional and Local Networks**

- Michael Moore

## An Australian Perspective...

## Outline

- What is Happening Now
- What is About to Happen
- What we want would like to see from IGS

## Australian Situation (Data) 

## South Pacific Network

## Other Stations

## Australian Situation Past/Now

- Only now submit new stations to be part of IGS if they are collocated with another technique:
- VLBI
- SLR
- Timing
- Stopped producing a regional solution
- Have not received data from external sources to GA for processing

## Now + Future

- Funding for the Densification
- VLBI
- SLR upgrade + campaigns
- Gravity (Absolute & relative)
- GNSS

## Slide 9

## Slide 10

## Implications

- Data Centre
- Data Flows
- Analysis Products

## Data Flows

**Data Flows**

- Regional DC

- Global DC

- Global DC

- Local DC

## Analytical Products

- RNAAC solutions now viable again, and we are investigating how to routine contribute again.
- Make solutions available to IGS and public
- Will need to develop a new product for general users in australia,

## Things to Keep in Mind

- Money for infrastructure but not people
- Need to do more for less
- Need to agree to adhere to certain standards

## IGS

- Standards
- ACs do a great job
- We love feedback (_[michael.moore@ga.gov.au](mailto:michael.moore@ga.gov.au)_ )
- Maintain high standards
- More open-source tools

## Make life easier

- Like to see a defined protocol from IGS to be used in a web service
- Data discovery
- Alerts
- Updates
- SOH, etc

## Questions/ Comments?