# Presentation: 447246

## WHO Collaborating Centre for Influenza - Australia

## Influenza in Australia 1992 - 2000

## Influenza in New Zealand

## Monthly distribution of influenza isolates

**Thailand 2000**

## Source of Virus Isolates Analysed Jan 2000 - Jan 2001

## Distribution of Types/SubtypesJan 2000 - Jan 2001

## Influenza A(H1) Analysis (1)

## Influenza A(H1) Analysis (2)

## Antigenic Analysis of A(H1N1) Isolates

**Jan - Aug 2000****	****	****Sept 2000  - Jan 2001**

## Influenza A(H1N1) Isolates

**Influenza A(H1N1) Isolates**
**HA1 Sequence Analysis**

## Influenza A(H1N1) Isolates

**Influenza A(H1N1) Isolates**
**NA Sequence Analysis**

## Influenza A(H3) Analysis

**Influenza A(H3) Analysis**

**ANTISERUM**

**A**

**B**

**C**

**D**

**E**

**F**

**Passage**

**Sample**
**Date**

**REF. Ag**

**SYD/5**

**MOS/10**

**PAN/2007**

**TEHRAN**

**SYD/203**

**ULAN**

**A**

- A/SYDNEY/5/97

**640**

- 640

- 640

- 640

- 1280

- 640

- 80

- CEK2,E5

**B**

- A/MOSCOW/10/99

- 320

**>2560**

- 640

- 640

- 1280

- 1280

- 160

- E7

**C**

- A/PANAMA/2007/99

- 80

- 40

**640**

- 160

- 160

- 640

- 40

- E7

**D**

- A/TEHRAN/14/99

- 160

- 640

- 640

**1280**

- 1280

- 1280

- 80

- X2,E3

**E**

- A/SYDNEY/203/2000

- 640

- 1280

- 640

- 640

**>2560**

- 1280

- 80

- E4

**F**

- A/ULAN/UDE/01/2000

- 320

- 80

- 320

- 640

- 320

**1280**

- 80

- E6

**TEST Ag**

- A/VICTORIA/346/2000

- 320

- 1280

- 640

- 640

- 640

- 640

- 160

- X,MD1

- A/WELLINGTON/13/2000

- 80

- 320

- 320

- 320

- 320

- 320

- 40

- MDX,MD1

- A/WAIKATO/7/2000

- 640

- 1280

- 640

- 1280

- 1280

- 1280

- 80

- MDX,MD1

- A/WAIKATO/10/2000

- 320

- 1280

- 1280

- 1280

- >2560

- 1280

- 160

- MEKX,MD1

- A/WAIKATO/14/2000

- 640

- 1280

- 1280

- 1280

- >2560

- >2560

- 320

- MDX,MD1

- A/WAIKATO/15/2000

- 320

- 640

- 640

- 640

- 640

- 640

- 80

- MEKX,MD1

- A/WAIKATO/17/2000

- 40

- 160

- 80

- 160

- 80

- 80

- <20

- MEKX,MD1

- A/STH AUST/101/2000

- 40

- 160

- 160

- 160

- 160

- 160

- 20

- MDX,MD1

- 28.09.00

- A/STH AUST/136/2000

- 160

- 640

- 640

- 1280

- 1280

- 320

- 40

- MDX,MD1

- 11.10.00

- A/BRISBANE/71/2000

- 80

- 160

- 160

- 160

- 160

- 160

- <20

- MDX,MD1

- 20.09.00

- A/BRISBANE/72/2000

- 80

- 640

- 640

- 640

- 1280

- 320

- 40

- MDX,MD1

- 23.09.00

- A/BRISBANE/75/2000

- 80

- 160

- 160

- 320

- 320

- 320

- 20

- MDX,MD1

- 03.10.00

## Antigenic Analysis of A(H3N2) Isolates

**A/Sydney**

**5.9%**

**A/Sydney (low)**

**12.3%**

**A/Moscow**

**67.8%**

**A/Moscow (low)**

**14.0%**

**Jan - Aug 2000****	****	****Sept 2000  - Jan 2001**

## Influenza A(H3N2) Isolates

**Influenza A(H3N2) Isolates**
**HA1 Sequence Analysis**

## Influenza A(H3N2) Isolates

**Influenza A(H3N2) Isolates**
**NA Sequence Analysis**

## Influenza B Analysis (1)

## Influenza B Analysis (2)

**ANTISERUM**

**PASSAGE**

**A**

**B**

**C**

**D**

**E**

**BEIJ/184**

**YAM/166**

**SICH/379**

**B/JOH/5**

**VIC/504**

**REF. Ag**

**A**

- B/BEIJING/184/93

**320**

- 320

- 640

- 640

- 320

- E10

**B**

- B/YAMANASH/166/98

- 320

**320**

- 1280

- 320

- 160

- E11

**C**

- B/SICHUAN/379/99

- 160

- 160

**640**

- 320

- 320

- E9

**D**

- B/JOHANNESBURG/5/99

- 320

- 320

- 1280

**320**

- 320

- E5

**E**

- B/VICTORIA/504/2000

- 80

- <20

- 160

- 160

**320**

- CEK1E1

**TEST Ag**

- B/C’CHURCH/22/2000

- 160

- 40

- 640

- 320

- 640

- MD3

- 02.10.00

- B/VICTORIA/114/2000

- 160

- 80

- 640

- 320

- 640

- MDX,MD1

- 26.09.00

- B/VICTORIA/107/2000

- 160

- 20

- 320

- 160

- 320

- MKX,MD1

- 16.08.00

- B/WELLINGTON/21/2000

- 160

- 40

- 640

- 320

- 640

- MD2

- 27.09.00

- B/BRISBANE/30/2000

- 160

- 40

- 640

- 320

- 640

- MDX,MD1

- 19.09.00

- B/BRISBANE/38/2000

- 320

- 80

- 640

- 320

- 320

- MDX,MD1

- 25.09.00

- B/STH AUST/85/2000

- 80

- <20

- 160

- 160

- 320

- MDX,MD1

- 07.09.00

- B/STH AUST/86/2000

- 80

- 20

- 320

- 160

- 320

- MDX,MD1

- 07.09.00

- B/VICTORIA/321/2000

- 80

- <20

- 320

- 160

- 640

- X,MD1

- 12.09.00

**SAMPLE**
**  ****DATE**

## Antigenic Analysis of Type B Isolates

**B/Shangdong**

**6.7%**

**B/Beijing**

**90.5%**

**B/Sichuan**

**2.9%**

**B/Beijing**

**60.3%**

**B/Sichuan**

**39.7%**

**Antigenic Analysis of Type B Isolates**

**Jan - Aug 2000****	****	****Sept 2000  - Jan 2001**

## 0

**0**

**2**

**4**

**6**

## Influenza B Isolates

**Influenza B Isolates**
**NA Sequence Analysis**

## Influenza Type A(H1N1) VaccineResponses - Older Adults 2000

**Influenza Type A(H1N1) Vaccine****Responses - Older Adults 2000**

## Influenza Type A(H3N2) VaccineResponses - Older Adults 2000

## Influenza Type B VaccineResponses - Older Adults 2000

## Slide 24