BEE-spoke-data/govdocs1-by-extension huggingface dataset:
# Presentation: 004612

## Monolithic, Active Pixel InGaAs Near Infrared Focal Plane Array Sensors Unlimited, Inc.Princeton, NJ

**ACCOMPLISHMENTS**
- Technology incorporated into hybrid focal plane array (FPA) consisting of an InGaAs photodiode array operable in the 0.9 μm to 1.7 μm spectrum at room temperature.
- Contains a single stage thermoelectric cooler with an integrated thermistor allowing the user to reduce the temperature for "high sensitivity" applications, such as low light level detection, or to stabilize the FPA in a varying ambient temperature.
- Easy to operate because the clock drivers and analog gain are all on one chip.
- High-resolution, active pixel architecture.
**GOVERNMENT SCIENCE/APPLICATIONS**
- Technology is utilized in Atmospheric Corrector (AC) instrument which will be flown on NASA’s Earth Observing-1 (EO-1) mission.  The AC will be tested for its ability to increase the accuracy of surface reflectance estimates.

**S****mall**
**B****usiness**
**I****nnovation**
**R****esearch**

- 1995 Phase II, SS5-040; 11/1/00

**COMMERCIALIZATION**
- A number of the processing techniques developed while working on this program have made their way into commercial devices that Sensors Unlimited sells to various customers.
- Technology used in many industrial and commercial applications such as fiber optics inspection, eye-safe covert surveillance, spectroscopy, laser beam profiling, laser and light detection and ranging (Ladar, Lidar), machine vision, telecommunications, and many other applications where near infrared detection is required.
- Sensors Unltd. was recently acquired by Finisar Corp., a fiber optic systems manufacturer in Sunnyvale, CA, in a stock deal presently worth over $800 million.

**Goddard Space Flight Center**

**INNOVATION**
- Developed an InGaAs/InP active pixel sensor wherein monolithic circuit functionality is integrated at every pixel.

- Points of Contact:
- 	-  NASA - Murzy Jhabvala; 301-286-5232
- 	-  Sensors Unlimited, Inc.- Gregory Olsen - 609-520-0610

**PHOTOGRAPH**

***InGaAs/InP Focal Plane Array***
# Presentation: 160768

## Laser Diode Reliability: BOKTask 04-032

** **

|  |   |   |
| --- | --- | --- |
|  |   |   |
|  |   |  |
|  |   |  |

**Total ROM Cost (non-CS) = $30K  **

**Description:**

**Benefits:**

**Schedule/Costs:**

**Risks:**

- Red, Yellow, or Green

**Lead Center/PI: Is: ****GSFC/Ott**
**Center Funding: ****30K (NEPAG will provide additional support to this task)**

**Non-NASA Organizations/Procurements:**
**none**

**CS FTEs = ?**

**Deliverables:**

- Laser diodes are key components of Lidar and communication systems.  They are used as the power source for communication transceivers and are used to pump high power lasers and fiber lasers for science data instrumentation.  Failure of these components results in failure of the instrument or system.
- Laser diode components are commercial off the shelf products at this time. Although some reliability issues are understood at the wafer level, the lack of knowledge related to the  the issues of packaging are still causing failures on space flight instrumentation. Recently, ICESAT experienced failures due to this lack of sufficient knowledge.  This task will focus of providing guidance and information related to the reliability of laser diodes to avoid future failures and ease usage of these components into space flight systems.

- This  task will provide the necessary guidance to usage and reliability of laser diodes such that systems depending on these components will function adequately throughout the life of the mission.  There is an extreme lack of sufficient information on this subject with a major emphasis on the lack of knowledge related to the higher power devices in which the failure modes are more pronounced.  Recently it has become apparent that this area of photonics must be investigated to avoid further failures such as ICESAT.

- Reports will be provided on the NEPP website on the usage, implementation, testing, and failure modes of laser diodes with emphasis on packaging and COTS devices.

- ICESAT, MOLA, Calipso
-                  Data collection

- Investigation of Issues

- Drafting guidelines and
-               reliability report

- Tactical  # 13 , Slide A
# Presentation: 721833

## NTSB review of crew actions during in-flight fires has resulted 

- in a series of recommendations calling for improved crew training
- and modification of cabin interiors to improve access to fires burning behind panels.

- -Jan 2002

## Incidents Included:

- Delta Flight 2030, MD-88, emergency landing at Cincinnati, Sept 17, 1999
- Flight attendant discharged halon extinguisher into return grills to extinguish fire.

- AirTran Flight 913, DC-9-32, emergency landing at Greensboro Aug 8, 2000
- Electrical fire in cockpit bulkhead, no attempt made by flight attendants to
- extinguish fire.

- American Flight 1683, MD-80, emergency landing at Dulles Nov 29, 2000
- Lightening strike induced arcing above cabin ceiling.  Halon extinguisher
- discharged into access hole cut with pocketknife, extinguishing fire.

- Air Canada Flight 797, DC-9, emergency landing at Cincinnati June 2, 1983
- Fire in aft lavatory behind sidewall, eventually destroyed aircraft, 23 fatalities.

## New Recommendations for 2002

- (A-01-83) Issue Advisory Circular (AC) that describes the need for crewmembers
- to take immediate and aggressive action in response to signs of an inflight fire.

- (A-01-84) Require principal operations inspectors to ensure that the contents of the
- advisory circular are incorporated into crewmember training programs.

- (A-01-85) Amend Part 121.417 to require participation in firefighting drills that
- involve actual or simulated fires during crewmember recurrent training and to
- require that those drills include realistic scenarios on recognizing potential fire
- situations, locating the origin of the fire, and fighting hidden fires.

- (A-01-86) Develop and require implementation of procedures or airplane modifi-cations that will provide the most effective means for crewmembers to gain access to areas behind interior panels for the purpose of applying extinguishing agent to hidden fires.  As part of this effort, the FAA should evaluate the feasibility of equipping interior panels of new and existing planes with ports, access panels, or some other means to apply extinguishing agent behind interior panels.

## Coordinated Approach to Hidden Fire Protection

- Accessibility

- Detection

- Suppression

- Fire Fighting Procedures

- Training and Equipment for Pilots & F/A’s

- Material Flammability

## Detection and Suppression of Hidden Fires

- Accessibility

- Feasibility of ports, access panels for discharging handheld extinguishers

- Detection

- Particle Sensing (Photoelectric, Laser, Light Attenuation, Ionization)

- Gas Sensing (Semiconductor, Infrared, Electrochemical)

- Temperature Sensing (Metallic Resistance, Thermistors, Piezoelectric, Fiberoptic)

- Suppression

- Manual (handheld extinguishers)

- Automatic (heat activated, or other control system linked to detection)

*What is the role of ventilation?*

## Future Hidden Fire Test Article

## Future Hidden Fire Test Article
# Presentation: 340041

## Measuring Disparitiesin Health at the State Level

**Jay S. Buechner, Ph.D.**
**Rhode Island Department of Health**

**NCHS Data Users Conference, July 15, 2002**

## Healthy People 2010 Goal:

_**Eliminate Health Disparities**_

**How do we measure progress?**

## Conceptual Challenges

**Operational Challenges**

## Operational Challenges

**  ****Small Numbers**
**  ****Comparability**
**  ****Data Quality  **

## Operational Challenges

**  *****Small Numbers***
**  ****Comparability**
**  ****Data Quality  **

## HP 2010 LHI Data Sources

**  ****Data from sample surveys****	****[e.g., BRFSS, YRBS]****	****	****=> Small **_**percentages**_
**  ****Data from “registries” ****	****[e.g., births, deaths] ****	****=> Small **_**numbers**_

## Minority Populations, Rhode Island, 2000

***Group***

***Number***

***Percent***

## HP2010 Leading Health Indicators by Race and Ethnicity, Rhode Island, 2002

## HP2010 Leading Health Indicators by Race and Ethnicity, Rhode Island

## Operational Challenges

**  ****Small Numbers**
**  *****Comparability***
**  ****Data Quality  **

## Comparability Issues

**  ****Demographic differences ****	****	****among areas**
**  ****Demographic changes ****	****	****	****over time**
**  ****Differences in targets ****	****	****	****across areas **
**  ****Changes in measurability ****	****	****of indicators  **

## Operational Challenges

**  ****Small Numbers**
**  ****Comparability**
**  *****Data Quality*****  **

## Data Quality Issues

** ****Sample surveys****	****Self-reported****	****	****Non-standard responses****	****Refusals****	****Bias**** ****“Registries”****	****Self-reported?****	****Missing data****	****Under-reporting**

## Hispanic Surname Study, RI Cancer Rates

**  ****From Bureau of Census:****	****List of 639 “heavily Hispanic” surnames**** ****	****Apply to:****	****RI Cancer Incidence (Males)****	****RI Cancer Deaths (Males, Females)**

## Hispanic Male Cancer Cases, Rhode Island, 1989-1998

**0**

**10**

**20**

**30**

**40**

**50**

**60**

**70**

**80**

**1989**

**1990**

**1991**

**1992**

**1993**

**1994**

**1995**

**1996**

**1997**

**1998**

**Year of Diagnosis**

**Number of Cases**

**Combined**

**Surname**

**Reported**

**Method**

**Hispanic Male Cancer Cases, Rhode Island, 1989-1998**

## Recommendations/Suggestions

**  ****Oversample/stratify in sample****	****	****	****	****	****surveys**
**  ****Choose an index that accommodates ****	****	****	****variety among states and localities**
**  ****Establish and support improved data ****	****	****	****collection  **
# Presentation: 886808

## Lynn M. Schuchter, M.D.Associate Professor of MedicineUniversity of  Pennsylvania Cancer Center

## Why is there so much controversy regarding the role of IFN in patients with high risk melanoma?

**Reasonable people disagree about the results from clinical trials and draw different conclusions from the data.**

## Does IFN improve overall survival in patients with melanoma?

## If IFN does improve overall survival in patients with melanoma, is the 10% difference worth the substantial toxicity associated with therapy?

## Does IFN improve overall survival?

**E1684: HD dose IFN vs observation**
**10% difference in OS**
**One sided log rank test used p=.0237**
**When two sided log rank test used p=.07**** **
**E 1684:Patients not stratified for the most important predictor of relapse and survival: *****the number of positive nodes*****. Therefore, possible imbalance between the two arms**

## Does IFN improve overall survival?

**E1690 High dose IFN vs low dose IFN vs observation**
**Intended as a confirmatory study to 1684**
_**No differences in OS**_
**5 year OS IFN 52%**
**5 year OS observation 55%**
**These efficacy results need to be considered in light of the substantial toxicity associated with one year of HDIFN. **** **

## IFN and Melanoma

**High dose IFN improves RFS by 10%.**
**Unclear whether HD IFN improves OS**
**Patients and physicians must consider making treatment decisions on RFS data and measures of quality of life. Many patients refuse to take IFN.**
**The majority of patient with Stage III melanoma die from their disease, despite high dose IFN**
**Critical to continue evaluating new agents in patients with high risk melanoma.**

## COLON CANCERAdjuvant Therapy of Stage II Disease

**Conclusion: therapy for stage II patients is controversial**
**In US, patients with stage II colon cancer may be randomized to:**
- CALGB trial: 	surgery alone vs MoAb 17-1a
- NSABP trial:	FU/LV vs FU/LV/oxaliplatin

## Treatment options for a patients with high risk melanoma should remain:

**Observation **
**High dose IFN**
**Participation in a clinical trial****- Vaccine****- Biochemotherapy****- Alternative IFN doses/schedule**
# Presentation: 683931

## Multi-Hit Reconstruction

-  **Analysis**
** ****Results**
** ****Conclusions**

- Samples
- Clusters
- Cuts (Unique Cut)
- Multiplicity of combination of segments

- Efficiency for each sample
-  distribution

## Clusters

- Using clusters definition to determine which segments to use in our analysis.

**Minimum number of segments**

**In cluster size ****5**** and ****3**** there is more than one possible segments configuration.**** **

## Samples

-  Using 6 different input files (from same sample of elastic events) differentiated by the number of channels turned on allowed per layer, from 1 to 6.

## Cuts

- Cuts before try to find positions:
- Multiplicity M of combination of segments  0 < M < 200.
- Cuts before track reconstruction:
- Must have one segment/plane (tougher cut).
- Fiducial cuts (same as used in elastic analysis).
- Data x  MC simulation  (same for single-hit and tougher for multi-hit).
- After reconstruction, we do** ****one** more cut:
**Unique cut** : We accept events in which only one track was reconstructed, or if the tracks have  values within our  resolution (0.0182).

## Unique Cut

-                observe  difference (delta ) between tracks reconstructed within same event.

- delta  = max - min

## Multiplicity of Combination of Segments

- The higher the combinations, harder to extract reliable information

- M<200

- 6 hits/layer

## Efficiency

- We define an efficiency for each file analyzed.
**eff = **_**          (events accepted-events discarded)           .        **_
**          ****170130**

## Efficiency

- It seems the efficiency flattens around 4 channels allowed per layer

- May use more channels (10), since no more CPU time is required

- Sample with 10 channels/layer on:   efficiency = 1.630.03
- (more than 10 channels/layer: noisy events)

**efficiency** (%)

**maximum hits/layer**

##  Distribution ( 10 channels/layer)

-  Distribution ( 10 channels/layer)

- 

- 

**Constant = (6.5********0.2)********10****2**
**Mean = (5.1********24.8)********10****-5**
**Sigma = (1.26********0.03)********10****-2**

**Constant = (3.4********0.1)********10****2**
**Mean = (4.6********0.5)********10****-3**
**Sigma = (1.47********0.04)********10****-2**

**Only single-hit**

**All events**

## Conclusion

-   CPU Time/event improves when multiplicity of combination of segments cut are used.
-  Efficiency seems to be independent of fiber hits above 4 hits/layer  may use 10 hits per layer without harm.
-  Improved sigma value and mean value (two orders of magnitude).
- - Next => Study diffractive events
# Presentation: 340038

## Emergency Data Distribution Network

***Proposal***
***to add an independent***
***GOES DCS Reception and Distribution System***
***to complement the***
***NESDIS Wallops Island Facility***

## GOALS

- Receive data from all DCPs transmitting in GOES DCS independently of Wallops Island.
- Locate facility a site sufficiently distant from Wallops Island to achieve event independence.
- Implement additional pilot signal at a location other than Wallops Island.
- Distribute data independently of Wallops Island.

## DRGS Project for GOES DCS emergency distribution system

- Locate DRGS systems at the USGS EROS Data Center in Sioux Falls, South Dakota to backup the GOES DCS Wallops Facility.
- USGS and NESDIS to share the costs for procurement of the DRGS systems.
- System to be primarily operated by USGS with support from NESDIS.
- Operational costs to be shared among users who agree to participate and NESDIS.

## STATUS

- A system model and component diagram has been developed.
- A meeting was held between representatives from USGS/WRD,  USGS/EDC and NESDIS to discuss requirements and responsibilities.
- The USGS/EDC has proposed a service level agreement to USGS/WRD which is being reviewed.
- A Specifications and a Statement of Work have been prepared and are being reviewed.
# Presentation: 690587

## 30th Annual FAA Aviation Forecast Conference   March 18, 2005

**30th Annual FAA Aviation Forecast Conference**   **March 18, 2005**

**Mainline Air Carrier & Regional/Commuter Breakout Panel:**
**  **
***Yield Trends***
**Bob Harrell -- Harrell Associates – New York City**

## Discussion Outline

**Discussion Outline**

- Database & Methodology
- Yields by Trip Length – 4 Groupings
- Short, Medium, Long, Transcon
- Yields by Carrier Type
- Legacy Carriers vs. Low Cost Carriers (LCCs)
- Yields by Origin City
- All Cities
- Cities with 5 or More Routes
- High/Low Routes
- Questions and Discussion

## Database & Methodology

**Database & Methodology**

- Top 40 Directional Routes – Sized by DOT Revenue
- 7 Major Carriers – 280 Directional Routes
- AA/DL/UA/CO/US/NW/HP
- Regular Business Fares
- Fare generally used by the business traveler.
- Refundable, No minimum stay, Advance purchase not to exceed 3 days
- Lowest One Way Fare – In effect on report date -- Weekly
- Yield – Based on DOT Mileage
- $/Mile
- Min/Max Range
- By Trip Length Group
- Position within Range -- % (1 – 100%)

## Yields Over Time – Short Trips

## Yields Over Time – Medium Trips

## Yields Over Time – Long Trips

## Yields Over Time – Transcon Trips

## Premium Over Time – Short Trips

## Premium Over Time – Medium Trips

## Premium Over Time – Long Trips

## Premium Over Time – Transcon Trips

## Yields Over Time – Short Trips

## Yields Over Time – Medium Trips

## Yields Over Time – Long Trips

## Yields Over Time – Transcon Trips

## Relative Yields by City

## Company Information – Harrell Associates

**Company Information – Harrell Associates**

**Bob Harrell**
**Harrell Associates**
**89 Washington Place**
**New York, NY 10011**
**Telephone:  212-358-1709 Fax: 212-656-1696**
**E-mail: **_[Bob@HarrellAssociates.com](mailto:Bob@HarrellAssociates.com)_** **
**Website: **_[www.HarrellAssociates.com](http://www.harrellassociates.com/)_
_**Company Profile and Brief Biography**_
**Harrell Associates **focuses in two areas: **Airfare and Airline Industry Consulting **and **Travel Industry Public Relations**.  It is currently providing benchmarking and media relations consulting on the travel and airline industries to a number of major financial institutions including: **American Express, Goldman Sachs **and** Merrill Lynch**.  **Harrell Associates **also engages in ad hoc consulting and market research projects in the travel industry.* *
- Mr. Harrell has extensive experience both with the distribution and supplier side of the travel industry.  At American Express, where he worked as a vice president for more than 7 years, he was responsible for the Airfare Management Unit and Airline Supplier Relations.  Prior to that, he was with Pan American Airways for more than 15 years.
# Presentation: 090122

## Annotating mRNAs & proteins

**Goals**
- Improve melanogaster annotation by using new genome sequences
- Annotate new genome sequences
- Provide a model for human annotation

- D-ENCODE 2004

## Dual genome predictors:The state of the art

- D-ENCODE 2004

## Right multi-genome model yields accuracy breakthrough

**GENSCAN**

**Mouse**
**comparison**

**Many small**
**improvements**

**Mouse, rat,**
**& chicken**

- D-ENCODE 2004

## Verification by RT-PCR

**Infrastructure in place**
- Automated target selection & primer design
- Automated analysis of results
- Shared archival databases for experiments
**Cost is low**
- PCR mix sequenced directly (skip the gel)
- Supplies & services ~$10 / RT-PCR + 2 reads
- 55% of novel *elegans* predictions confirmed

- D-ENCODE 2004

## We predict TSS and UTR exons in mammals

- D-ENCODE 2004

## Traces reveal alternative splices

- D-ENCODE 2004

## Translation start sites

**State of the art**
- Guess! Longest ORF or 1st ATG or Kozak...
- I am not aware of any standard methodology
- If there are experimentally confirmed starts, I don’t know how to find them in the databases
**What can be done?**
- Old fashioned protein sequencing?
- Mass spectrometry?
- What about N-terminal clipping?

- D-ENCODE 2004

## Why buy the fly and spurn the worm?

**Better model for human**
- Intron length & prediction difficulty
- Species at a variety of evolutionary distances
- No pair of worms is as close as mammals
**Better system for method development**
- Species at a variety of evolutionary distances

- D-ENCODE 2004
# Presentation: 659447

## Flats Container Development

**November 6, 2002**

***Flats Container Development***

## Goal

**Goal**
**To demonstrate Flats mail processing of trayed palletized loads received directly from mailers**
**Reduce labor intensive mail prep operations**
**Incremental improvement not enough**

## Background

**Flat Mail provided by several Mailers**
**Engineering developed Alternative Flats Tray for testing (15 & 20 in.)**
**ATR modified Flats Feeder Assist System for Flats Tray handling**
**Engineering to evaluate methods & equipment requirements**

## Methods Tested

**Methods Tested**

**Assisted loading using a bridge table for manual loading from pallet**
**Manually unload from tray to feeder**
**Setting load directly on extended table with FFAST**
**Using FFAST: rotate load, load directly on ledge, remove strapping and container**

## Slide 5

## Slide 6

## Results

**Results**

**New methodology for processing flats with**
**Alternative Flats Tray**
**FFAST**
**Reduction in work hours associated with mail prep operations**
**Impact on bundle processing**

## Issues

**Further testing of trays on pallets needed **
**stacking of trays & transportability**
**Mailer feedback**
**Can trays be utilized in their process?**
**Will there be sufficient volume to build full trays?**
**Current Presort requirements**
**FFAST deployment`**

**Notes:**
Postal Service
All 3 digit presort will ensure full trays but will impact AFSM processing windows by forcing a primary sort. 
Do the workhour savings from bypassing the SPBS and 035 operation justify the change to AFSM processing ? 
5 digit trays may require a mini 035 operation to HASH the schemed 5 digit trays for a compatible AFSM run.  
What workhours would be involved with this ?  
Will a FFAST be required in this operation as well ?
Will a mix of 3 & 5 digit be palatable for USPS and mailers?

Mailers
Will the alternate tray cost them in time or equipment ?
Will parallel bundle/ tray makeup be required during transition?
Are mailer costs offset by reduced number of bundles, reduced shrink-wrap & strapping costs, reduced makeup requirements, etc ?
# Presentation: 313529

## Simulations Required for ReviewPeter Jacobs, LBNL

- Basis for EMCal physics case:
-  Trigger: 0/, e, jet
-  Full jet reconstruction
-  Gamma/pi0 discrimination
-  Electron/hadron discrimination
-  (neutron background)
**Need to assess impact of EMCal on key physics measurements**
- not sufficient only to quote resolutions or background suppression factors
- Need to assess impact of reduces acceptances (staging and “upgrade”  scenarios)

- An EMC for ALICE

## Trigger

- 0/ trigger: PHOS technology in hand
-  no simulations needed of hardware performance (?)
- Jet trigger: see talks by pmj and Chris
-  imho understood sufficiently except for HLT rejection performance (use offline reco to study)
- Electrons: new topic, needs targeted study
-  some back of envelope calculations would help and may be all that is possible in time remaining
-  compare to other ALICE lepton measurements
-  new manpower needed!

- An EMC for ALICE

## /0

-  See Marco’s talk
-  need to incorporate cross sections, 0 ratio
-  estimate fragmentation photon contributions

- An EMC for ALICE

## Electron/hadron discrimination

- Role of EMCal in ALICE for electrons:
- vs TRD?
- in coincidence with TRD?
- e-mu coincidence w/ muon arm?
- No time before December to dig into this in detail
**needs new effort**

- An EMC for ALICE

## Full jet reconstruction

- IMHO this is the centerpiece of the physics case for the EMCAL
- Thus far there are detailed studies of specific response but afaik only partial assessment of physics performance
- Need to assess finite resolution in light of physical spectrum
- Need to assess effects of jet quenching
- Varying background: p+p, minbias Pb+Pb, central Pb+Pb
**Need to compare leading hadrons vs charged jets vs full jets (w/ EMCal)**

- An EMC for ALICE

## A. Morsch, ECT talk Oct 05

- ?

- An EMC for ALICE

## -fn input

- -fn input

- physical
- spectrum

- Not the clearest way to plot it , need to redo and expand...

- Ereco/Ethrown

- Ethrown

- An EMC for ALICE

##  Jet physics simulations

- TPC+EMCal response: use detailed geant w/ -fn input parameterize
- Throw physical distribution w/ parameterized response
- Look at bias on parton energy distribution
-  Leading particle vs charged jets vs full jets
-  pp vs PbPbminbias vs PbPbcentral
-  quenching models

- IMHO this issue is central to physics case: need to make signficant progress in next month

- An EMC for ALICE

## Reduced acceptance

- 0 etc: rate scales linearly with acceptance
- Finite size jet patch: slightly more complicated but still geometric
- No advantage to detailed simulations:
-  Tom  should define the scenarios, then redo the simple acceptance calculations:

- Full acceptance

- An EMC for ALICE
# Presentation: 760559

## Community Planning Training  

**Community Planning Training  **

**8-1**

## Community Planning Training    

**Community Planning Training    **

**8-2**

## Identify the next steps in the Communities That Care process.

**Community Planning Training  **

**8-3**

- Identify the next steps in the *Communities **That Care* process.

## Participants will be able to:
Explain the tasks involved in Phase Five: Implementing and Evaluating the Community Action Plan.
Develop and agree on a final work plan and time line for transitioning to Phase Five.

- Participants will be able to:
- Explain the tasks involved in Phase Five: Implementing and Evaluating the Community Action Plan.
- Develop and agree on a final work plan and time line for transitioning to Phase Five.

**Community Planning Training  **

**8-4**

## Community Planning Training  

**Community Planning Training  **

**8-5**

## Secure funding.

**Community Planning Training  **

**8-6**

- Implement tested, effective programs with fidelity.
- Complete evaluations.
- Plan for Community Board maintenance.
- Maintain public relations efforts.

## Members of the Funding work group

**Community Planning Training  **

**8-7**

- Members of the Resources Assessment and Evaluation work group
- Representatives from agencies involved inplan or program implementation
- Outside evaluators
- Other Community Board members, as appropriate

## Finalize systems-change strategies, and community-level and program-level outcomes.

**Community Planning Training  **

**8-8**

- Finalize systems-change strategies, and community-level and program-level outcomes.
- Complete program investigation and selection.
- Address preliminary evaluation plans.
- Prepare and distribute the Community Action Plan.

## Brainstorm actions.

- Assign actions and set deadlines.
- For each action, identify necessary resources and any barriers or issues to address.

**Community Planning Training  **

**8-9**

## Include dates for:

- key actions from the work plan
- the Community Plan Implementation Training
- the next Community Board meeting
- conferences and community events
- other Community Board activities

**Community Planning Training  **

**8-10**

## Community Planning Training  

**8-11**
# Presentation: 675225

## PerfluoropolyetherLubricating Fluids

-  Development of a series of fluids with good low temperature 		(-40oC) and high temperature  (260oC) properties as well as 		oxygen stability
**                             ****COMMERCIALIZATION**
-  Company has leveraged this technical knowledge to expand into 	specialty fluorocarbon chemical production for uses other than 		lubrication
-  Technology licensed to the 3M Company
-  Received $750K Air Force contract for optimizing a chemical 		structure for use in high performance jet engines
- Firm employment doubled as a result of SBIR activities

***EXFLUOR RESEARCH CORP.******AUSTIN, TX***

**S****mall**
**B****usiness**
**I****nnovation **
**R****esearch**

**     ****GOVERNMENT/SCIENCE APPLICATIONS**
-  Useful in the electronic industry and in Space Shuttle and 	high performance aircraft where lubricants are required 		that have a wide liquid range and a low volatility
-  Technology can increase the operating temperature of jet 	engines, thus increasing engine efficiency

- 1984 Phase 2; SS-114; 8/29/96

- Lewis Research Center

**Perfluoropolyether****Lubricating Fluids**

***Structure for perfluoropolyether***
# Presentation: 500685

## THORpex (Hawaii 2003) field program planning and EOS objectives Univ. Wisconsin 

- Chris Moeller (CIMSS; U. Wisc.)
- Steve Ackerman (CIMSS; U. Wisc.)
- Bryan Baum (NASA; U. Wisc.)
- Rich Frey (CIMSS; U. Wisc.)

## Hawaii-2003 ER-2 DeploymentWisconsin EOS-related objectives

- Aqua MODIS L1B validation (clear sky)
- multi-angle
- warm and cold scenes
- Aqua MODIS Cloud product validation
- Cloud heights (primarily cirrus)
- Cloud particle phase (multi-layer, supercooled)
- Cloud Mask validation (thin cirrus detection)
- Cloud overlap studies
- Ocean color (clear sky)

## Logistics to accomplish Wisconsin EOS objectives
Align ER-2 with Aqua orbital track
fly racetracks (L1B) or parallel lines (Clouds) with Aqua overhead
overfly MOBY buoy near Hawaii (ocean color)

- Logistics to accomplish Wisconsin EOS objectives
- Align ER-2 with Aqua orbital track
- fly racetracks (L1B) or parallel lines (Clouds) with Aqua overhead
- overfly MOBY buoy near Hawaii (ocean color)

## March 19

- Terra orbital
- track

- Balloon

- B

- A

- D

- C

- Strawman
- ER-2 flight lines
- for Gulf Mexico
- MODIS Cal/Val
- mission on
- Mar 19, 2001

- Flight Sequence:
- A-B-C-D-
- A-B-C-D

## BF#1

- BF#4

- BF#6

- BF#5

- March 22
- Terra orbital
- track

- A

- B

- C

- D

- E

- F

- G

- H

- CF

- Strawman #2
- ER-2 flight lines
- for SGP Central
- Facility mission
- on Mar 22, 2001

- Flight Sequence:
- A-B-C-D-
- E-F-G-H-
- A-B-C-D-
- E-F-G-H

## Hawaii-2003 ER-2 Flight Range.  

- Hawaii-2003 ER-2 Flight Range.

## Slide 7

## ER-2 Payload Positions (TX-2001 configuration)

## Slide 9

## Slide 10

## Slide 11

## Slide 12

## Slide 13

## Intentionally Blank

## Slide 15
# Presentation: 759725

## Free Space Laser Communications

- Phillip Dykstra
- WareOnEarth Communications Inc.
- phil@sd.wareonearth.com

- 25 June 2001

## Introduction

- Free space laser communications
- a.k.a. Free Space Optics, Optical Wireless
- Basically a laser and a telescope
- Most are protocol independent
- Typical range < 4 km (.5, 1, 2, 4, 8km)
- Typical bandwidths: 10, 100, 1000 Mbps
- Lucent 10 Gbps DWDM (TeraBeam)

## Example Systems

- LightPointe
- Flight series

- ICS
- Sky series

- LSA
- Supraconnect

## Transmitters

- LED (single or multiple)
- 1 mW typical
- Laser (single or multiple)
- 10-20 mW typical, up to 100 mW
- Usually 785 or 850 nm, some 1310 nm
- Eye safety limit: 1.5 mW/cm^2 at 785 nm
- Multiple transmitters boost power, may also reduce scintillation fades

## Detectors

- PIN Diodes
- -43 dBm typical
- Avalanche Photo Diodes (APD)
- -53 dBm typical (also greater dynamic range)
- Single or multiple detectors
- Larger aperture increases receive power, reduces scintillation fades
- Design goal: BER < 10^-9 typical

## Laser Link GeometryCritical Design Parameters

**Beam Divergence = 3 mrad**

**Diameter = 3 m**
**Beam area = 70686 cm****2**

**Distance = 1km**

**Receive area = 200 cm****2**

- Adapted from a LightPointe Technology slide

**Transmit Power**

**Receiver sensitivity**

## System Comparison(OC3 1km products)

- System Comparison(OC3 1km products)

-                                             **OpticalAccess           ICS              LightPointe**
**Transmit Power (mW)**   10 (10 dBm)     100 (20 dBm)       4 (6 dBm)
**Beam Diverg (mrad)**             2.5                     11                       3
**Receive Area (cm^2)**             52                     232                    200
**Min Recv Power (nW)**    100 (-40 dBm)   32 (-45 dBm)    50 (-43 dBm)
**Price**                                    $19.5k                $25k                   $24k

## Example Loss BudgetOptical Access T1000X

- Tx Power (dBm) =  10.00
- Distance =        686 meters
- Beam Diameter =  1.72 meters
- Beam Area =      2.31 meters^2
- Geometric loss =  -26.65 dB
- Rx Max (dBm) =  -16.65
- Rx Min (dBm) =   -40.00
- Margin (dBm) =    23.35
-                                -3 dB mispointing
-                             - 10 dB scintillation
-                            = 10 dB for atmospheric attenuation

- +10 dBm

- -40 dBm

- -17 dBm

- -20 dBm

- -30 dBm

## Equipment Delivery

## T1000X Interface Box

## T1000X Full View

## Platform Mount

## Eastward View

## Westward View

## Concrete Pedestal Base

## Front of T1000X

## Slide 17

## Fog Event (19 June 01)

## Fog Event (cont)

## Packet Loss

## Availability

- Availability = Prob (Visibility > Vmin)

-                       V > 1.5km      V > 0.5km
- San Diego         98%                99.1%
- Las Vegas        99.9%              100%

-  99.999% is nearly impossible, except in the desert
-  Some products add backup microwave (lower speed)

## For More Info

- _[http://wcisd.hpc.mil/](http://wcisd.hpc.mil/)_
-  Served by the laser link
-  Laser and Weather stats
-  Links to laser company web sites
- phil@sd.wareonearth.com
# Presentation: 527905

## NGS Help Desk Operations and Procedures

- Marc Muher
- Help Desk Manager
- MSW, MCP, A+

## NGS Uses Dell PCs

- “One throat to choke”
- One number to call
- Consistency within enterprise and NOS
- Known quantity
- Interoperability of parts

## Minimum system standards

- Technology changes very quickly
- New part numbers, new technology
- Minimum specs, as of 10/05

## Minimum Desktop

- 3 Ghz Pentium 4 processor (DC or HT)
- 1 GB DDR2 RAM
- Dual monitor capable
- DVD +/- RW drive
- <100 GB SATA hard drive
- Windows XP Pro
- Floppy drive

## Minimum Laptop

- Standardize on Latitude 610/810
- 2 Ghz Pentium M processor
- 1 GB DDR2 RAM
- Largest hard drive available
- DVD +/- RW drive
- Warranty with “complete care”
- Wireless will be discussed later

## Microsoft Office Software

- MS Office XP
- No plans to upgrade to 2003 at this time
- No site license for any Microsoft product
- Install Word, PowerPoint, and Excel
- Outlook not usually installed – security risk
- Visio and Project separate products

## Standard Software

- MS Office XP
- Adobe Acrobat 6 (7 under discussion)
- ArcGIS 9.1
- Mozilla Thunderbird (email standard)
- Mozilla Firefox
- Winzip 9.x
- Oracle Calendar client
- McAfee Antivirus
- CoreFTP

## Peer to Peer software

- Bittorrent, Napster, Limewire, etc
- Completely unacceptable
- If needed for business use, requires prior written permission from NGS Deputy Director
- Also covers using Realplayer, ITunes to download music onto NGS computer

## Inappropriate Files

- Anything without legitimate business use
- Licensed, copyrighted, or other
- MP3, WMA, AAC, WMV, MPG, etc
- PCs are scanned on a regular basis for these files

## Passwords and Screen Lock

- Enforced in SSMC/ Norfolk
- Should be used on all NOAA PCs
- Passwords change every 90 days
- At least 8 characters
- At least one upper and one lower case
- At least one number and special character
- No dictionary words
- Unique passwords
- Screens lock after 15 minutes

## Backups

- Users are still responsible for backing up their own data
- Data put on home drives (“Z”) are redundant and backed up daily
- Help Desk is working on backup of all systems

## McAfee antivirus software

- Can be used for home PCs
- The only software licensed for home use
- Can be acquired by:
- Link on intranet ngsweb.ngs.noaa.gov
- NOAA IT Security page _[https://csp.noaa.gov](https://csp.noaa.gov/)_
- Asking help desk for a CD
- Should be set to update daily
# Presentation: 720809

## Common Review Initiative Update

- Boston Guaranty Agency Summit
- August 31, 2005

## CRI Concept

- Guarantors are combining resources to conduct a single review of large lenders and servicers
- These CRI reviews will go toward meeting the requirements of 682.410(c)(1) for each CRI-participating guarantor

## Significant Events

- By the end of the CRI pilot, review teams will have conducted 11 CRI reviews
- On-site visits completed at Suntech, MOHELA, Wells Fargo, AES, ACS, Edfinancial, KHESLC, Nelnet, SLMA, Educaid
- Citicorp visit scheduled for 9/26

## Significant Events

- One new participant - Georgia
- Non-participants currently are:
- Alaska
- CSAC/EdFund
- New Hampshire
- North Carolina

## Significant Events

- New leadership for current and next biennium
- Rick Buckingham, USA Funds *Chair through 2005*
- Becky Collins, Student Loan Guarantee Foundation of Arkansas *Chair for 2006-2007*

## Significant Events

- Successful reviewer training session
- October 2004 meeting in Texas
- Approximately 60 attendees
- Another training session scheduled for October 25-26, 2005

## Significant Events

- Change in review scheduling policy
- Not all guarantors using same standards for review selection
- Agreed to selection based on previous year’s volume as of 9/30

## Significant Events

- Creation of quality assurance group
- Co-chaired by Greg Schweitzer (Great Lakes) and Bernie Girata (AES/PHEAA)
- Conducted by two reviewers NOT part of review team
- Performing analyses of completed reviews to ensure proper documentation
- Before reports issued, reviewing workpapers and reports for consistency and quality

## Significant Events

## Significant Events

- Planning for CRI’s future
- Currently a pilot program approved through 12/31/2005
- Met with ED to discuss CRI’s future
- Delivering request for permanence today

## CRI Goals and Report Card

- Improve the quality of lender program reviews conducted by guarantors (including non-CRI reviews)
- Reduce redundancy of reviews by guarantors

## Report Card on Quality

- Attribute testing
- Statistically valid sampling
- Continual tweaking of workpapers
- Six reviewers instead of 1-2
- Consistent documentation
- Reviewer training
- Quality review process

## Report Card on Redundancy

- Can look at this two ways
- If all guarantors had conducted servicer reviews, CRI eliminated 125 guarantor reviews that would have been conducted
- 11 CRI reviews covered 248 reviews required by 682.410(c), eliminating 237 individual lender reviews

## Report Card on Redundancy

- Average cost of CRI review = $5,783 (6 reviewers)
- Average cost of non-CRI review = $964 (1 reviewer)
- Guarantor savings
- Servicer reviews - $67,491
- All reviews - $175,459

- Questions??
# Presentation: 681951

## Keith Cogdill, PhD

October 2, 2004
Seattle, Washington
Pacific Northwest Chapter
Medical Library Association

- October 2, 2004
- Seattle, Washington
- Pacific Northwest Chapter
- Medical Library Association

**Measuring and Communicating the Value of Library and Information Services**

## Slide 2

## Overview:Approaches to Value

- Background: journal prices & hospital closures
- Quantifying value
- Measuring performance
- Contributions as indicators of value – CLIS approach

## Average Journal Costs

- 	1984           $125.57                ---
- 	1994           $321.39	       	156%
- 	2002           $789.44           528%

## Hospitals

- 						_**1975**__**	**_**	**_**2000**_
- All hospitals 		 	 	7,156 		5,810
- 	Federal 		 	     	   382 	   	   245
- 	Non-Federal 		  		6,774 	  	5,565
- 		Community 	 	  	5,875 		4,915 				Non-profit 	 	3,339 		3,003 				For-profit	 	   775 		   749 				State/local gov’t 	1,761 		1,163
- _[Health, United States, 2003. Table 106](http://www.cdc.gov/nchs/data/hus/tables/2003/03hus106.pdf)_

## Approaches to Value:Quantifying Value

- Valuing intangibles
- Cost-benefit analyses (CBA)
- Return on investment (ROI)
- Findings from studies of IT –    The “IT Paradox”

## Approaches to Value:Quantifying Value

- “In FY01 Mn/DOT Library services provided an estimated total of $8,386,500 in reduced costs and added value for a benefits to cost ratio of 12:1.”

**Approaches to Value:****Quantifying Value**

- _[http://](http://www.dot.state.mn.us/library/mndot_library_benefits.html)__[www.dot.state.mn.us/library/mndot_library_benefits.html](http://www.dot.state.mn.us/library/mndot_library_benefits.html)_

## Approaches to Value: Measuring Performance

- LibQUAL+
- Balanced Scorecard Approach (BSA)
- Financial
- Internal business
- Customer
- Learning and innovation

## Contributions to individual/organization
Development of taxonomy 
Literature review
Key informant interviews
Focus group
Questionnaires

- Development of taxonomy
- Literature review
- Key informant interviews
- Focus group
- Questionnaires

**Approaches to Value:****Contributions as ****Indicators of Value**

## Approaches to Value:Contributions as Indicators of Value

- Taxonomy of LIS contributions
- Mission concepts
- Clinical care
- Management of operations
- Education
- Research and innovation
- Service
- Organizational goals
- LIS contributions

## Approaches to Value:CLIS Approach

- Select appropriate organizational goals
- Identify LIS contributions relevant to organizational goals
- Obtain data on correspondence between LIS contributions and LIS services
- Select measures for services
- Collect and analyze data for selected measures
- Plan and sustain communication with administrators
- Evaluate findings and revise as necessary

## Next Steps to Consider

- Request administrator’s input
- Begin/review data collection
- Develop communication plan

## Keith Cogdillcogdilk@mail.nlm.nih.gov
# Presentation: 149509

## Hypersonic Neurocontrol Actuator and Testbed (LoFLYTE®)

**Hypersonic Neurocontrol Actuator and Testbed (LoFLYTE®)**
- Accurate Automation Corporation, Chattanooga, Tennessee

- Innovation

- Accomplishments

- Commercialization

- Government/Science Applications

**Points of Contact:**
- NASA LaRC, J. Larry Hunt, (757) 864-3732
- Accurate Automation, Richard Saeks, (423) 894-4646
- 1993 SBIR Phase II; NAS1-20404

- The LoFLYTE® vehicle was the first known powered flight of a hypersonic waverider configuration at low speed, which proves that this shape can takeoff and land from a runway.
- Accurate Automation has developed a neural controller representing the first of a new generation of “smart” actuator controllers and a testbed vehicle on which to test fly the neural control system.

- Designed and developed a hybrid/adaptive controller which automatically adapts to changing flight environments, such as speed, altitude, wind, and turbulence
- Designed a test apparatus to allow evaluation of the performance of the hybrid neural/adaptive controller in various flight environments and simulated the effect of control surface and actuator damage
- Built a 100” wind tunnel model and performed an extensive series of wind tunnel tests to evaluate the low speed performance of a Mach 5 waverider configuration to compare to real flight data
- Flight tested a 100” radio-controlled model of a jet-powered vehicle with the 419th Flight Test Squadron at the Air Force Flight Test Center at Edwards AFB
- Flight tested the neural network flight control system

- LoFLYTE® on takeoff at Edwards AFB

- The LoFLYTE® shape can be scaled up to a faster and larger configuration for an unmanned combat aerial vehicle, a cruise missile, or a hypersonic transport aircraft.
- The LoFLYTE® testbed aircraft is being used to test additional aerospace technologies including Accurate Automation’s Neural Air Data Sensor subsystem, neural network engine controller, “Fly-by-Light” communications protocol, an advanced health monitoring system, and an advanced real-time data acquisition and control system.

- The technologies developed in this program were included in the proposal submitted by the Accurate Automation-led team for NASA’s Future-X Pathfinder program.
- Accurate Automation has proposed the use of this shape as a UCAV, a hypersonic cruise missile, and a hypersonic target to the U.S. Navy.
- The LoFLYTE® team was awarded a Small Business Administration Tibbetts Award in 1996.
- LoFLYTE®’s neural network flight control system was awarded “Best of What’s New” by *Popular Science* in 1996.
- Accurate Automation has licensed this technology to a major aerospace corporation.
# Presentation: 912658

## Reconsolidation, Cocaine and

- Matrix Metalloproteinases

- Barbara A. Sorg
- Washington State University

## Addiction is Learned

## Enzyme                                    MMP      

- Collagenases			MMPs-1, 8, 13, 18
- Gelatinases			MMPs-2, 9
- Stromelysins			MMPs-3, 10, 11
- Membrane-type			MMPs 14-17, 24, 25
- 					(= MT1-6 MMPs)
- Others:
- (Matrilysins				MMP-7, 26
- Metalloelastase			MMP-12

## pre

**NMDA** **R**

- glutamate

- ECM Molecules

- post

## pre

**NMDA** **R**

- Active MMP

- ECM Molecules

- post

## MMP inhibition with FN-439 impairs 

- MMP inhibition with FN-439 impairs
- water maze performance

- Meighan et al. J. Neurochem. (In Press)

## Does MMP inhibition prevent acquisition or

- consolidation of cocaine-induced CPP?

## MMP inhibition attenuates acquisition

- & consolidation of CPP

## Slide 9

## Does MMP inhibition prevent reconsolidation?

## MMP inhibition disrupts reconsolidation of CPP

## Activity

- 0

- 25

- 50

- 75

- 100

- FN-439

- aCSF

- Photocell counts per min
- spent on cocaine-paired side

## Repeated exposure to MMP inhibitor in context only 

- Repeated exposure to MMP inhibitor in *context only*
- does not alter reinstatement of CPP

## Conclusion

## Amygdala

- MMP-3

- GAPDH

- Cocaine Prime

- Saline Prime

- Time After Cocaine-Primed Reinstatement

**MMP-3 mRNA**
**(% Saline)**

**Amygdala**

- 0

- 50

- 100

- 150

- 200

- 250

- 300

- 1 hr

- 3 hr

- *

- 3 hr

- Cocaine-Primed Reinstatement
- Increases MMP-3 mRNA in Amygdala

## Summary of reconsolidation studies 

-  as applied to drug abuse

- _Pharmacological agents can be used to:_

-   Disrupt the conditioned reward value of the CS 		(light) (Pavlovian to instrumental transfer, in 		absence of drug) Lee et al. (2005) Neuron 47:795.

-   Disrupt  the drug-associated contextual memory
- 	(in absence of drug)
- 	also, Miller and Marshall (2005) Neuron 47:873.

-   Disrupt the drug-associated contextual memory
- 	(in presence of drug)

## Slide 17

## Questions/Challenges Ahead

-   Does disruption of reconsolidation reduce *craving* (in 		addition to *expression* of cocaine-seeking 			behavior)?

-   If the memory is partially present after disruption of 	reconsolidation, does relapse to drug-taking 	cause reconsolidation and therefore 		strengthening of the memory?

-   Is the memory impairment from disruption of 			reconsolidation long-lasting, or will “maintenance 	treatments” be required?

-   Does extinction alter (facilitate or impair) reconsolidation
- 	of a drug memory?

## ?

**Collaborators: Drs. Joseph Harding & Jay Wright**

## “Use almost can change the stamp of nature”

-     *Hamlet*

- Can disruption of reconsolidation change the stamp of drugs?

## Slide 21

## Examples of stimuli affecting brain MMPs

- MMP-2	Hippocampus	Seizures, transient ischemia
- 					 traumatic brain injury
- MMP-3	Cortex		transient ischemia,
- 					traumatic brain injury
- MMP-9	Hippocampus	Spatial learning,
- 					Sleep deprivation,
- 					Alzheimer’s disease
- MMP-9	Cortex		Spatial learning, transient
- 					ischemia

- _    __MMP      Brain structure          Up/downregulation     _