# Presentation: 356772

## Industry-University Partnerships in Pharmaceutical Development

**Azevan Pharmaceuticals, Inc.**
**Bethlehem, PA **

**Neal G. Simon, Ph.D.**

**Dept. of Biological Sciences**
**Lehigh University**
**Bethlehem, PA **

## Azevan Pharmaceuticals, Inc.

** ****Founded in 1999 as Serenix Pharmaceuticals, LLC**
** ****Began operations in January, 2000**
** ****Initial Funding: Ben Franklin ($150,000)**
** ****Financing and Investors:**
-      **1999-2002:** **Ben Franklin Technology Partners: $450,000**
**     ****2001- present: Natl. Institutes of Health: $2.0 million**
**     ****2004: Life Sciences Greenhouse of Central PA: $500,000**
**     ****2005: Series A (June, 2005)**
**                 **

** ****Azevan Pharmaceuticals, Inc.**

***Mission:  Develop next generation pharmaceuticals for the treatment of ***
***          ******	******central nervous system disorders and cardiovascular disease***

## Drug Development Timeline: A Formidable Barrier

** ****Azevan Pharmaceuticals, Inc.**

**0           2          4       5       6           8         10        12     13          15        16        ****	****    ****	****	****        **
**	****	****	**

**YEARS**

## Fostering Strategic Relationships

** ****University**
** ****State and Federal Funding**
** ****CROs and Consultants**
** ****Venture Capitalists**

** ****Azevan Pharmaceuticals, Inc.**

## Strategic Partnership: Lehigh University

** ****Incubator Space**
** ****Industrial Liaison Program**
** ****Access to Lehigh Infrastructure**
** ****Faculty Expertise**
** ****Build Credibility**

## Lehigh University Partnership: Getting Started

**Lehigh University Partnership: Getting Started**

** ****A Willing Partner**
** ****Initial Contact**
** ****University Structure**
** ****Programs for Industry**
** ****Formalizing the Relationship**
** ****Contractual obligations**
** ****University vs. Company Rights**

## University Partnerships: Policies, Practices, and Compliance

**Faculty Rules and Procedures**
**Conflict of Interest and Disclosures**
**Technology Transfer Office**
**Intellectual Property Policy**
**Licensing and Bayh-Dole Requirements**
**Company Rights**

## University Partnership: A Critical First Step

** ****Pennsylvania State Agencies**
** ****Ben Franklin Technology Partners**
** ****Life Sciences Greenhouse of Central PA**
** ****National Institutes of Health**
** ****STTR**
** ****SBIR**

## Funding: NIH STTR/SBIR Grants

** ****Support pre-clinical development**
** ****Non-dilutive effect on Company’s equity**
** ****Demonstrate technological feasibility**
** ****Add to Company credibility**
** ****Attract outside investors**

## Strategic Partnerships: CROs & Consultants

** ****Expertise**
** ****Network**
** ****Credibility**
** ****Cost Effective**
**    **

** ****Azevan Pharmaceuticals, Inc.**

**Strategic Partnerships: CROs & Consultants**

***It’s about people as much as technology***

## Strategic Partnerships:  The VC World 

** ****Know what makes you different**
-  **Know why you’re in business**
** ****Know what makes VCs tick**
** ****It takes time**

** ****Azevan Pharmaceuticals, Inc.**

## Establishing Credibility

** ****Azevan Pharmaceuticals, Inc.**

**0           2          4       5       6           8         10        12     13          15        16        ****	****    ****	****	****        **
**	****	****	**

**YEARS**

## Azevan Pharmaceuticals, Inc.