**[2005 cancer Biomedical Informatics Grid (]{.smallcaps}ca[BIG™)
]{.smallcaps}**

**[Industry Partners Meeting]{.smallcaps}**

***"Linking Communities and Information to Eliminate Suffering and Death
due to Cancer"***

Natcher Conference Center

National Institutes of Health

Bethesda, Maryland

Friday, September 30, 2005

[]{.mark}

[]{.mark}

**AGENDA AT A GLANCE**

+-----------+----------------------------+------------------+---------+
| **Session | **Session Description**    |                  | *       |
| Time**    |                            |                  | *Room** |
+-----------+----------------------------+------------------+---------+
| [8:00am   | **Registration (coffee     |                  |         |
| --        | service provided)**        |                  |         |
| 9         |                            |                  |         |
| :00am]{.s |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [9:00am   | **Introduction by NCI      |                  | Aud     |
| --        | Senior Leadership -- *Anna |                  | itorium |
| 9         | Barker***                  |                  |         |
| :15am]{.s |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [9:15am   | **NCICB Welcome and caBIG™ |                  | Aud     |
| -- 9:45   | Program Overview --        |                  | itorium |
| am]{.s    | *Kenneth Buetow***         |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [9:45am   | **caBIG™ Compatibility --  |                  | Aud     |
| -- 10:30  | *Peter Covitz & Sue        |                  | itorium |
| am]{.s    | Dubman***                  |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| []{.mark  | **BREAK**                  |                  |         |
| }[10:30am |                            |                  |         |
| -- 10:45  |                            |                  |         |
| am]{.s    |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [10:45am  | **caBIG™ - Cancer Center   |                  | Aud     |
| --11:15   | Perspective -- *J. Robert  |                  | itorium |
| am]{.s    | Beck***                    |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [11:15am  | **caBIG™ - Commercial      |                  | Aud     |
| -- 11:45  | Opportunities -- *Kenneth  |                  | itorium |
| am]{.s    | Buetow***                  |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [11:45am  | **LUNCH -- on your         |                  | See     |
| --        | own\*\***                  |                  | Be      |
| 12        |                            |                  | low\*\* |
| :45pm]{.s |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [12:45pm  | **CONCURRENT BREAKOUT      |                  |         |
| -- 2:30   | SESSIONS**                 |                  |         |
| pm]{.s    |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
|           | ***caBIG™ Compatibility*** | ***caBIG™        |         |
|           |                            | Commercial       |         |
|           |                            | Opportunities*** |         |
+-----------+----------------------------+------------------+---------+
|           | -   **caBIG™ Architecture  | -   **Commercial |         |
|           |     -- *Avinash            |     Perspectives |         |
|           |     Shanbhag***            |     -- *David    |         |
|           |                            |     Aronow       |         |
|           | -   **Vocabulary & Common  |     (Ardais) &   |         |
|           |     Data Elements --       |     Sharon       |         |
|           |     *George Komatsoulis*** |     Settnek      |         |
|           |                            |     (SAIC)***    |         |
|           | -   **Compatibility        |                  |         |
|           |     Governance and         | ```{=html}       |         |
|           |     Certification Models   | <!-- -->         |         |
|           |     -- *Peter Covitz***    | ```              |         |
|           |                            | -   **Funding    |         |
|           | *Ad hoc discussions        |     Mechanisms   |         |
|           | following presentation*    |     for          |         |
|           |                            |     Commercial   |         |
|           | **Room: E1/E2**            |     Entities --  |         |
|           |                            |     *Kenneth     |         |
|           |                            |     Buetow***    |         |
|           |                            |                  |         |
|           |                            | -   **Licensing  |         |
|           |                            |     and          |         |
|           |                            |     Intellectual |         |
|           |                            |     Property --  |         |
|           |                            |     *Wendy       |         |
|           |                            |     Patterson*** |         |
|           |                            |                  |         |
|           |                            | *Ad hoc          |         |
|           |                            | discussions      |         |
|           |                            | following        |         |
|           |                            | presentation*    |         |
|           |                            |                  |         |
|           |                            | **Room:          |         |
|           |                            | Auditorium**     |         |
+-----------+----------------------------+------------------+---------+
| [2:30pm   | **BREAK**                  |                  |         |
| -- 2:45   |                            |                  |         |
| pm]{.s    |                            |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+
| [2:45pm   | **General Session: Open    |                  | Aud     |
| -- 3:30   | Questions and Answers with |                  | itorium |
| pm]{.s    | Panel**                    |                  |         |
| mallcaps} |                            |                  |         |
+-----------+----------------------------+------------------+---------+

**\*\*LUNCH** -- [Meal Tickets for Natcher Cafeteria Available at
Registration for \$10 cash only]{.smallcaps}

**About the Speakers**

**Anna Barker, Ph.D.**

***Deputy Director for Advanced Technologies and Strategic Partnerships
of the National Cancer Institute (NCI)***

Dr. Barker serves as the Deputy Director for Advanced Technologies and
Strategic Partnerships of the National Cancer Institute (NCI). In this
role she plans and coordinates the implementation of integrative,
multi-disciplinary and multi-sector programs to accelerate the
development and translation of new knowledge and advanced technologies
into effective interventions to prevent, detect and treat cancer. Under
her leadership, the NCI has recently launched programs in bioinformatics
and nanotechnology and is currently developing initiatives in proteomics
and biospecimens to enable cancer research. Dr. Barker completed her
Ph.D. at Ohio State University, where she trained in immunology and
microbiology. Her research interests include experimental therapeutics,
tumor immunology, and free-radical biochemistry in cancer etiology,
prevention and treatment.

Dr. Barker has a long history in research and the leadership and
management of research and development, technology transfer and product
commercialization in the non-profit and private sectors. Prior to
entering the biotechnology sector, she was a senior executive at
Battelle Memorial Institute for 18 years where she developed and led a
large group of scientists and technical staff working in areas such as
drug discovery and development, pharmacology and biotechnology,
including several NCI-sponsored research programs. In the private sector
she co-founded and served as the CEO of a public biotechnology company,
focused in therapeutics discovery and development; and subsequently
founded and served as the CEO of a private company dedicated to the
transfer and deployment of technologies to prevent, diagnose and treat
cancer.

She is a member of the Steering Committee of C-Change and Chairperson of
the C-Change Cancer Research Team. She is a member of the DOD Breast
Cancer Research Program Integration Panel, and a past chairperson of the
BCRP Integration Panel. Dr. Barker has served in several capacities for
the American Association for Cancer Research (AACR), including the Board
of Directors and chairperson of the Public Science Policy and
Legislative Affairs Committee; and the NCI, including membership on the
Board of Scientific Counselors for the Division of Cancer Etiology and
chairperson of the Cancer Center Support Review Study Section. Dr.
Barker has received a number of awards for her contributions to
research, cancer patients, professional and advocacy organizations and
the ongoing national effort to prevent and cure cancer, including a
named fellowship from the AACR.

**Kenneth Buetow, Ph.D.**

***Director, National Cancer Institute Center for Bioinformatics***

Dr. Buetow received a B.A. in Biology from Indiana University in 1980,
and a Ph.D. (1985) in Human Genetics from the University of Pittsburgh.
From 1986 to 1998 Dr. Buetow was at the Fox Chase Cancer Center in
Philadelphia, where his group generated and electronically distributed
the human genetic map. Dr. Buetow serves a dual role for the National
Cancer Institute. He is the Director of the NCI Center for
Bioinformatics (NCICB) and Chief of the Laboratory of Population
Genetics (LPG). His research interests include the application of
genetics and genomics tools to understand the genetic basis of complex
traits.

The NCICB coordinates and deploys informatics in support of NCI research
initiatives. Its goal is to maximize the interoperability and
integration of NCI research and its related information. The Center
participates in the evaluation and prioritization of the NCI\'s
bioinformatics research portfolio, conducts or facilitates research that
is required to address the NCICB\'s mission, serves as the locus for
strategic planning to address the informatics needs of NCI\'s expanding
research initiatives, establishes information technology standards (both
within and outside of NCI), and communicates, coordinates, or
establishes information exchange standards.

The LPG conducts human genetic and genomics research, both at the bench
and using informatics tools. The major goal of this research program is
to apply and extend human genetic analysis methods and resources to
better understand the genetics of complex phenotypes, specifically human
cancer.

Dr. Buetow has spearheaded efforts of the Genetic Annotation Initiative
(GAI), an attempt to identify variant forms of the cancer genes
identified through the NCI Cancer Genome Anatomy Project (CGAP). He is
particularly interested in genetic variations that make individuals more
susceptible to liver, lung, prostate, breast, and ovarian cancer. His
group combines computational tools with bench-top laboratory findings to
understand how genes and environment interact to increase cancer risk.

**Peter Covitz, Ph.D.**

***Director, Bioinformatics Core Infrastructure, National Cancer
Institute Center for Bioinformatics***

Peter Covitz is currently Director of Bioinformatics Core Infrastructure
at the NCI Center for Bioinformatics in Rockville, Maryland. Prior to
joining the NCI, Dr. Covitz was Vice President of Professional Services
at InforMax, Inc. where he ran the bioinformatics service and support
division of the company. Earlier in his career Dr. Covitz worked as a
research scientist and manager at Incyte Pharmaceuticals and Molecular
Applications Group. Dr. Covitz did his graduate work on transcriptional
regulation at Columbia University, and post-doctoral training in
genomics and bioinformatics at Stanford University.

**Sue Dubman**

***Director Applications, National Cancer Institute Center for
Bioinformatics***

Currently Director of Applications for the Center for Bioinformatics at
the National Cancer Institute, Ms. Dubman has responsibility for
managing developments that cross multiple domains, from support of basic
scientific investigation to drug approval. Prior to NCI, Ms. Dubman
served as CIO at 4 health care and services companies, including a \$2
billion subsidiary of Bristol-Myers Squibb, an information services
company owned by Cardinal Health, an e-commerce startup providing
Internet-based health care products and services in partnership with the
United Nations, and a \$2 billion services organization with 2000
locations worldwide. Ms. Dubman did her graduate work at Brown
University in population sciences and her undergraduate work at the
University of Missouri.

**J. Robert Beck, MD**

***Vice President for Information Services and Chief Information Officer
at Fox Chase Cancer Center***

Dr. J. Robert Beck is Vice President for Information Services and Chief
Information Officer at Fox Chase Cancer Center. In this role he has
responsibility for bioinformatics, clinical computing and administrative
information technology. He also is a Senior Member in Population
Sciences, where he leads the academic Program in Evaluative Sciences
(biostatistics, bioinformatics, and health services research). Dr.
Beck's undergraduate education was completed at Dartmouth College with a
mathematics major modified with biology. After medical school at Johns
Hopkins University, and a pathology residency, he took a fellowship in
Clinical Decision Making at the New England Medical Center. He has held
faculty and administrative positions at Dartmouth Medical School, Oregon
Health Sciences University, and Baylor College of Medicine.

Dr. Beck as a principal investigator has held grants from various
institutes within the National Institutes of Health and from major
foundations and corporations. His major research focus is on decision
modeling in medicine, where his work has centered on the development and
refinement of methods of outcome assessment. Two products of his early
work, the Declining Exponential Approximation of Life Expectancy (DEALE)
and the Markov process outcome model, are now standard methods in
clinical decision analysis. In the bioinformatics arena Dr. Beck is
interested in genetic pathways, and the application of information
technology to problems in biological data management.