+---------+---------+------------------------+-----------------------+---+
| 30-DAY  |         |                        |                       |   |
| ERROR   |         |                        |                       |   |
| R       |         |                        |                       |   |
| ESPONSE |         |                        |                       |   |
| TO      |         |                        |                       |   |
| "       |         |                        |                       |   |
| REVISED |         |                        |                       |   |
| D       |         |                        |                       |   |
| RINKING |         |                        |                       |   |
| WATER   |         |                        |                       |   |
| ASS     |         |                        |                       |   |
| ESSMENT |         |                        |                       |   |
| FOR     |         |                        |                       |   |
| NAPRO   |         |                        |                       |   |
| PAMIDE" |         |                        |                       |   |
| AND     |         |                        |                       |   |
| "D      |         |                        |                       |   |
| RINKING |         |                        |                       |   |
| WATER   |         |                        |                       |   |
| ASS     |         |                        |                       |   |
| ESSMENT |         |                        |                       |   |
| FOR     |         |                        |                       |   |
| NAPR    |         |                        |                       |   |
| OPAMIDE |         |                        |                       |   |
| FOR     |         |                        |                       |   |
| TERR    |         |                        |                       |   |
| ESTRIAL |         |                        |                       |   |
| USES".  |         |                        |                       |   |
| DP      |         |                        |                       |   |
| Barcode |         |                        |                       |   |
| D       |         |                        |                       |   |
| 305601. |         |                        |                       |   |
| 11      |         |                        |                       |   |
| /12/04. |         |                        |                       |   |
+=========+=========+========================+=======================+===+
| **H     | **Page  | **Error Correction**   | **EFED Response**     |   |
| eader** | and     |                        |                       |   |
|         | L       |                        |                       |   |
|         | ocation |                        |                       |   |
|         | (D      |                        |                       |   |
|         | ocument |                        |                       |   |
|         | is not  |                        |                       |   |
|         | pagin   |                        |                       |   |
|         | ated)** |                        |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Summary | 1,      | The vapor pressure     | The vapor pressure    |   |
|         | pa      | should be corrected to | used (4 x 10^-6^      |   |
|         | ragraph | 1.7x10^-7^ torr (see   | torr) is an error,    |   |
|         | 1       | Product Chemistry      | but substituting the  |   |
|         |         | Considerations,        | correct value (1.7 x  |   |
|         |         | D305599, 10/29/04).    | 10^-7^ torr) does not |   |
|         |         |                        | change the estimates  |   |
|         |         |                        | of surface water      |   |
|         |         |                        | exposure and risk     |   |
|         |         |                        | using PRZM-EXAMS. The |   |
|         |         |                        | correct value was     |   |
|         |         |                        | placed in the         |   |
|         |         |                        | document at this      |   |
|         |         |                        | time.                 |   |
+---------+---------+------------------------+-----------------------+---+
| Summary | 2,      | **The SCI-GROW surface | Substantive comment   |   |
|         | pa      | water drinking water   | that will be          |   |
|         | ragraph | concentration is       | addressed after       |   |
|         | 3       | overestimated and      | public comment has    |   |
|         |         | should be recalculated | been received.        |   |
|         |         | using correct input    |                       |   |
|         |         | values.**              |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Surface | 3,      | Add "ppb" after the    | "ppb" label will be   |   |
| Water   | pa      | value 1.67.            | added at this time.   |   |
| M       | ragraph |                        |                       |   |
| odeling | 2       | Modeling does not take | Banding comment is    |   |
| of      |         | into account that only | substantive comment   |   |
| Terr    |         | 1/3 of an orchard acre | and will be addressed |   |
| estrial |         | receives a napropamide | after public comment  |   |
| Uses    |         | treatment since band   | has been received.    |   |
| for     |         | applications are made. |                       |   |
| Napr    |         |                        |                       |   |
| opamide |         |                        |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Surface | 3,      | The EECs presented for | Substantive comment   |   |
| Water   | Table 1 | GA pecan reflect two   | that will be          |   |
| M       | and     | applications of 6 lb   | addressed after       |   |
| odeling | A       | ai/A at 7 day          | public comment has    |   |
| of      | ppendix | intervals. There are   | been received. The    |   |
| Terr    | A,      | no current labels with | modeling was          |   |
| estrial | Table 1 | a food crop use rate   | conducted based on    |   |
| Uses    |         | at 6 lb ai/A. Labels   | the Use Closure Memo  |   |
| for     |         | allow two applications | between the           |   |
| Napr    |         | only in the Western    | registrant and        |   |
| opamide |         | region. The minimum    | Agency.               |   |
|         |         | reapplication interval |                       |   |
|         |         | is 90 days. **A        | Error was corrected   |   |
|         |         | reassessment of the    | by adding references  |   |
|         |         | EEC values for various | in Table 1 to the     |   |
|         |         | scenarios should be    | footnotes.            |   |
|         |         | re-done using correct  |                       |   |
|         |         | label information.**   | Document will be      |   |
|         |         |                        | provided to the       |   |
|         |         | There is a footnote 1  | registrant.           |   |
|         |         | at the end of the      |                       |   |
|         |         | table but it is not    |                       |   |
|         |         | found in the table.    |                       |   |
|         |         |                        |                       |   |
|         |         | The registrant does    |                       |   |
|         |         | not have a copy of the |                       |   |
|         |         | "2/8/02                |                       |   |
|         |         |                        |                       |   |
|         |         | Input Parameter        |                       |   |
|         |         | Guidance" to verify    |                       |   |
|         |         | that the input values  |                       |   |
|         |         | are appropriate.       |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Surface | 4,      | There are no current   | Substantive comment   |   |
| Water   | Table 2 | labels with a pecan    | that will be          |   |
| M       | and     | use rate at 6 lb ai/A. | addressed after       |   |
| odeling | A       | The maximum use rate   | public comment has    |   |
| of      | ppendix | for pecans is 4 lb     | been received. The    |   |
| Terr    | A,      | ai/A. A second         | modeling was          |   |
| estrial | Table 2 | application is only    | conducted based on    |   |
| Uses    |         | allowed for pecans     | the Use Closure Memo  |   |
| for     |         | grown in the Western   | between the           |   |
| Napr    |         | region at a 90 day     | registrant and        |   |
| opamide |         | interval. Napropamide  | Agency.               |   |
|         |         | is mainly applied as a |                       |   |
|         |         | band application, not  | Substantive comment   |   |
|         |         | broadcast. Modeling    | that will be          |   |
|         |         | should be revised to   | addressed after       |   |
|         |         | take into              | public comment has    |   |
|         |         | consideration a lower  | been received. The    |   |
|         |         | total lb ai applied    | modeling was          |   |
|         |         | per acre.              | conducted based on    |   |
|         |         |                        | the Use Closure Memo  |   |
|         |         | Appendix A, Table 2    | between the           |   |
|         |         | Input Parameters:      | registrant and        |   |
|         |         |                        | Agency.               |   |
|         |         | GA pecans do not       |                       |   |
|         |         | receive a second       | The vapor pressure    |   |
|         |         | application so no      | used (4 x 10^-6^      |   |
|         |         | interval between       | torr) is an error,    |   |
|         |         | applications should be | but substituting the  |   |
|         |         | included in this       | correct value (1.7 x  |   |
|         |         | assessment.            | 10^-7^ torr) does not |   |
|         |         |                        | change the estimates  |   |
|         |         | The vapor pressure     | of surface water      |   |
|         |         | should be corrected to | exposure and risk     |   |
|         |         | 1.7 x 10^-7^ torr. The | using PRZM-EXAMS. Use |   |
|         |         | water solubility is    | of the correct water  |   |
|         |         | 7[4]{.underline} mg/L  | solubility value (74  |   |
|         |         | at 2[5]{.underline}    | mg/L) also does not   |   |
|         |         | °C; delete the "x 10"  | change estimated      |   |
|         |         | after the °C. (see     | exposure. The correct |   |
|         |         | Product Chemistry      | water solubility      |   |
|         |         | Considerations).       | value was placed in   |   |
|         |         |                        | the document at this  |   |
|         |         | The photolytic         | time.                 |   |
|         |         | half-life should be    |                       |   |
|         |         | corrected to 0.0047 d  | The correct half-life |   |
|         |         | (6.8 min x 1hr/60 min  | for parent            |   |
|         |         | x 1 day/24 hr) as      | napropamide (6.8      |   |
|         |         | noted in the EFED risk | minutes) was added to |   |
|         |         | assessment document    | the document.         |   |
|         |         | (D303453, 11/30/04,    |                       |   |
|         |         | pages 20, 28).         | Substantive comment   |   |
|         |         |                        | that will be          |   |
|         |         | Footnote 2 should be   | addressed after       |   |
|         |         | corrected to delete    | public comment has    |   |
|         |         | the reference to the 6 | been received.        |   |
|         |         | lb ai/A rate.          |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Ground  | 5,      | Delete reference to    | Substantive comment   |   |
| Water   | pa      | the 6 lb ai/A rate     | that will be          |   |
| Ass     | ragraph | since this is not a    | addressed after       |   |
| essment | 2       | use pattern for        | public comment has    |   |
|         |         | napropamide except in  | been received         |   |
|         |         | turf and ornamentals.  |                       |   |
|         |         | Repeat applications    | Substantive comment   |   |
|         |         | are only permitted for | that will be          |   |
|         |         | certain crops in the   | addressed after       |   |
|         |         | Western region.        | public comment has    |   |
|         |         |                        | been received.        |   |
|         |         | **The SCI-GROW surface | Modeling was          |   |
|         |         | water drinking water   | conducted using the   |   |
|         |         | concentration is       | Input Parameter       |   |
|         |         | overestimated and      | Guidance dated        |   |
|         |         | should be recalculated | 2/28/02.              |   |
|         |         | using current input    |                       |   |
|         |         | values.**              |                       |   |
+---------+---------+------------------------+-----------------------+---+
| Ground  | 5,      | The table mistakenly   | Reference to document |   |
| Water   | Table 3 | includes a reference   | is unclear. This      |   |
| Ass     | and     | to "NC Tobacco", which | comment will be       |   |
| essment |         | should be changed to   | addressed after       |   |
|         | A       | "GA Pecan".            | public comment has    |   |
|         | ppendix |                        | been received.        |   |
|         | B,      | There are no current   |                       |   |
|         | Table 1 | labels with a pecan    | Substantive comment   |   |
|         |         | use rate at 6 lb ai/A. | that will be          |   |
|         |         |                        | addressed after       |   |
|         |         | The maximum use rate   | public comment has    |   |
|         |         | for pecans is 4 lb     | been received.        |   |
|         |         | ai/A. A second         |                       |   |
|         |         | application is only    | Substantive comment   |   |
|         |         | allowed for pecans     | that will be          |   |
|         |         | grown in the Western   | addressed after       |   |
|         |         | region. Even if a      | public comment has    |   |
|         |         | second application     | been received. The    |   |
|         |         | were made, the typical | modeling was          |   |
|         |         | interval between       | conducted based on    |   |
|         |         | herbicide applications | the Use Closure Memo  |   |
|         |         | is 90 days.            | between the           |   |
|         |         |                        | registrant and        |   |
|         |         | Napropamide is mainly  | Agency.               |   |
|         |         | applied as a band      |                       |   |
|         |         | application, not       |                       |   |
|         |         | broadcast so that      |                       |   |
|         |         | modeling should take   |                       |   |
|         |         | into consideration a   |                       |   |
|         |         | lower total lb ai      |                       |   |
|         |         | applied per acre.      |                       |   |
|         |         | There is precedent for |                       |   |
|         |         | EFED to use 33% of the |                       |   |
|         |         | total use rate for     |                       |   |
|         |         | band applications in   |                       |   |
|         |         | tree nut and fruit     |                       |   |
|         |         | orchards and this      |                       |   |
|         |         | factor should be       |                       |   |
|         |         | applied to the risk    |                       |   |
|         |         | assessments for        |                       |   |
|         |         | napropamide.           |                       |   |
+---------+---------+------------------------+-----------------------+---+

+----------+-----------+-----------------------+----------------------+---+
| 30-DAY   |           |                       |                      |   |
| ERROR    |           |                       |                      |   |
| RESPONSE |           |                       |                      |   |
| TO "EFED |           |                       |                      |   |
| RISK     |           |                       |                      |   |
| AS       |           |                       |                      |   |
| SESSMENT |           |                       |                      |   |
| FOR THE  |           |                       |                      |   |
| NAP      |           |                       |                      |   |
| ROPAMIDE |           |                       |                      |   |
| REREGI   |           |                       |                      |   |
| STRATION |           |                       |                      |   |
| ELI      |           |                       |                      |   |
| GIBILITY |           |                       |                      |   |
| DO       |           |                       |                      |   |
| CUMENT". |           |                       |                      |   |
| DP       |           |                       |                      |   |
| Barcode  |           |                       |                      |   |
| D303453. |           |                       |                      |   |
+==========+===========+=======================+======================+===+
| **       | **Page    | **Error Correction**  | **EFED Response**    |   |
| Header** | and       |                       |                      |   |
|          | L         |                       |                      |   |
|          | ocation** |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 1, List   | Remove the 50-WP,     | Information on       |   |
|          | of end    | 5-G, and 2-E, since   | formulations         |   |
|          | use       | they have been        | supported in         |   |
|          | products  | cancelled. Current    | reregistration will  |   |
|          |           | products include:     | be corrected in      |   |
|          |           | Devrinol 50-DF        | document at this     |   |
|          |           | Selective, 2-G        | time.                |   |
|          |           | Ornamental, 10-G      |                      |   |
|          |           | Selective, 4-F        |                      |   |
|          |           | Selective, 4-F        |                      |   |
|          |           | Ornamental, 50-DF     |                      |   |
|          |           | Ornamental, 2-EC and  |                      |   |
|          |           | 2-EC Ornamental.      |                      |   |
|          |           | Remove 50-DF at the   |                      |   |
|          |           | end of the list since |                      |   |
|          |           | it is a duplicate.    |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| I.       | 4, first  | In the fourth line,   | Information on       |   |
| E        | paragraph | remove "wettable      | formulations will be |   |
| xecutive |           | powder", as all       | corrected in         |   |
| Summary  |           | registrations with    | document at this     |   |
|          |           | this formulation have | time.                |   |
|          |           | been cancelled.       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| I.       | 4, second | See comments under    | Registrant intends   |   |
| E        | p         | Section I.B of this   | to submit additional |   |
| xecutive | aragraph; | document for comments | information that     |   |
| Summary  | 8, 5^th^  | on the difference     | will be considered   |   |
|          | paragraph | between the           | at a later date.     |   |
|          |           | laboratory and field  | EFED will review the |   |
|          |           | data.                 | data when it is      |   |
|          |           |                       | submitted to the     |   |
|          |           |                       | Agency.              |   |
+----------+-----------+-----------------------+----------------------+---+
| I.       | 4, third  | Regarding the comment | Substantive comment  |   |
| E        | paragraph | "Because the label    | that will be         |   |
| xecutive |           | does not specifically | addressed after      |   |
| Summary  |           | require soil          | public comment has   |   |
|          |           | incorporation...."    | been received.       |   |
|          |           | All labels specify    |                      |   |
|          |           | that the product must |                      |   |
|          |           | be mechanically or    |                      |   |
|          |           | watered-in. Newer     |                      |   |
|          |           | labeling has included |                      |   |
|          |           | the comment that the  |                      |   |
|          |           | product should be     |                      |   |
|          |           | incorporated or       |                      |   |
|          |           | irrigated within 24   |                      |   |
|          |           | hours.                |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A.       | 4, first  | Devrinol 50-WP has    | Information on       |   |
| P        | paragraph | been cancelled.       | formulations will be |   |
| otential |           |                       | corrected in         |   |
| Risks to |           | No other label allows | document at this     |   |
| No       |           | for the 6 lb ai/A use | time.                |   |
| n-target |           | rate except on turf   |                      |   |
| Non-en   |           | and ornamentals.      | Substantive comment  |   |
| dangered |           |                       | that will be         |   |
| O        |           | For cranberries, the  | addressed after      |   |
| rganisms |           | 15 lb ai/A rate is    | public comment has   |   |
|          |           | for muck soils only   | been received.       |   |
|          |           | found in the PNW;     |                      |   |
|          |           | this rate represents  | Substantive comment  |   |
|          |           | less than 3% of the   | that will be         |   |
|          |           | entire cranberry      | addressed after      |   |
|          |           | acreage and is not    | public comment has   |   |
|          |           | representative of the | been received.       |   |
|          |           | maximum use rate (9   |                      |   |
|          |           | lb ai/A). Risk        |                      |   |
|          |           | assessments should be |                      |   |
|          |           | refined to reflect    |                      |   |
|          |           | these more            |                      |   |
|          |           | representative use    |                      |   |
|          |           | rates.                |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Aquatic  | 5, second | The registrant has    | Specific data on     |   |
| organism | p         | data for *Lemna* and  | *Lemna* and          |   |
| risks    | aragraph, | *Anabaena* which will | *Anabaena* will be   |   |
|          | 8         | be submitted.         | considered after the |   |
|          |           |                       | data is submitted to |   |
|          |           |                       | the Agency.          |   |
+----------+-----------+-----------------------+----------------------+---+
| M        | 5         | Risk assessment       | Substantive comment  |   |
| ammalian |           | inputs need to be     | that will be         |   |
| Risks    |           | corrected.            | addressed at a later |   |
|          |           |                       | date.                |   |
+----------+-----------+-----------------------+----------------------+---+
| B.       | 6, third  | Applications of       | Substantive comment  |   |
| P        | paragraph | napropamide are never | that will be         |   |
| otential |           | made at 7-day         | addressed at a later |   |
| Risks to |           | intervals between     | date.                |   |
| No       |           | applications but      |                      |   |
| n-target |           | rather 90 day         |                      |   |
| Listed   |           | intervals. Risk       |                      |   |
| and      |           | assessments should be |                      |   |
| En       |           | refined to include    |                      |   |
| dangered |           | this information.     |                      |   |
| O        |           |                       |                      |   |
| rganisms |           |                       |                      |   |
| /Aquatic |           |                       |                      |   |
| Listed   |           |                       |                      |   |
| Species  |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| C. Major | 8, bullet | Data are available    | Specific data on     |   |
| Uncer    | 1         | for *Lemma* and       | *Lemna* and          |   |
| tainties |           | *Anabaena* and will   | *Anabaena* will be   |   |
| and Data |           | be submitted.         | considered when they |   |
| Gaps     |           |                       | are submitted to the |   |
|          |           |                       | Agency.              |   |
+----------+-----------+-----------------------+----------------------+---+
| C. Major | 8, bullet | Applications of       | Substantive comment  |   |
| Uncer    | 2         | napropamide are never | that will be         |   |
| tainties |           | made at 7-day         | addressed after      |   |
| and Data |           | intervals between     | public comment has   |   |
| Gaps     |           | applications but 90   | been received.       |   |
|          |           | days. Risk            |                      |   |
|          |           | assessments should be |                      |   |
|          |           | refined to reflect    |                      |   |
|          |           | this actual use       |                      |   |
|          |           | pattern.              |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| C. Major | 8, bullet | The aqueous           | The correct          |   |
| Uncer    | 3, 4      | photolysis half-life  | half-life for parent |   |
| tainties |           | should be corrected   | napropamide (6.8     |   |
| and Data |           | to 6.8 min.           | minutes) was added   |   |
| Gaps     |           |                       | to the document.     |   |
+----------+-----------+-----------------------+----------------------+---+
| C. Major | 8, bullet | See comments under    | Substantive comment  |   |
| Uncer    | 5         | Section II.C.of this  | that will be         |   |
| tainties |           | document for a        | addressed after      |   |
| and Data |           | discussion of the     | public comment has   |   |
| Gaps     |           | difference between    | been received.       |   |
|          |           | the laboratory and    |                      |   |
|          |           | field data.           |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| C. Major | 8, bullet | Foliar dissipation    | Substantive comment  |   |
| Uncer    | 6         | data were never       | that will be         |   |
| tainties |           | developed for         | addressed after      |   |
| and Data |           | napropamide since it  | public comment has   |   |
| Gaps     |           | is applied to the     | been received.       |   |
|          |           | soil or areas under   |                      |   |
|          |           | trees and only a      |                      |   |
|          |           | small portion of the  |                      |   |
|          |           | applied product will  |                      |   |
|          |           | reach off-site areas  |                      |   |
|          |           | from spray drift or   |                      |   |
|          |           | runoff.               |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A.       | 9         | Remove the reference  | Information on       |   |
| Stressor |           | to the 50-WP and 2-E  | formulations will be |   |
| Source   |           | since these           | corrected in         |   |
| and      |           | registrations have    | document at this     |   |
| Dist     |           | been cancelled.       | time.                |   |
| ribution |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 2\.      | 10, first | The registrant notes  | EFED used best       |   |
| Overview | paragraph | that the data from    | available data from  |   |
| of       |           | NCFAP is almost 8     | all sources.         |   |
| P        |           | years old and not     |                      |   |
| esticide |           | representative of     |                      |   |
| Usage    |           | current sales. See    |                      |   |
|          |           | Section II of this    |                      |   |
|          |           | document for further  |                      |   |
|          |           | comments.             |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 10,       | Correct the following | Substantive comment  |   |
|          | second    | statement: "Maximum   | that will be         |   |
|          | paragraph | label rates...range   | addressed after      |   |
|          |           | from 2 lbs ai/A to 8  | public comment has   |   |
|          |           | lbs ai/A". No label   | been received.       |   |
|          |           | bears a single        |                      |   |
|          |           | application rate of 8 | Substantive comment  |   |
|          |           | lb ai/A for any crop. | that will be         |   |
|          |           |                       | addressed after      |   |
|          |           | Correct the following | public comment has   |   |
|          |           | statement: "Maximum   | been received.       |   |
|          |           | rates                 |                      |   |
|          |           | for...tomatoes...hot  |                      |   |
|          |           | peppers...            |                      |   |
|          |           | strawberries... are 2 |                      |   |
|          |           | applications per year |                      |   |
|          |           | at 4 lbs ai/A or one  |                      |   |
|          |           | application per year  |                      |   |
|          |           | at 6 lbs ai/A." All   |                      |   |
|          |           | labels for these      |                      |   |
|          |           | crops allow a single  |                      |   |
|          |           | application at 4 lbs  |                      |   |
|          |           | ai/A.                 |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 2\.      | 10, Table | Delete all references | Information on       |   |
| Overview | 1         | in the table to the   | formulations will be |   |
| of       |           | WP formulation.       | corrected in         |   |
| P        |           | Correct the           | document at this     |   |
| esticide |           | formulation type      | time.                |   |
| Usage    |           | "FIC" to              |                      |   |
|          |           | "F[l]{.underline}C:   |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 2\.      | 10,       | The footnotes c and d | The reference to     |   |
| Overview | Almond,   | deleted from the WP   | these footnotes was  |   |
| of       | Pistachio | rows should be moved  | placed in the table  |   |
| P        |           | elsewhere in the      | under the heading    |   |
| esticide |           | document.             | "application         |   |
| Usage,   |           |                       | interval."           |   |
|          |           |                       |                      |   |
| Table 1  |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 10-13,    | [All]{.underline} nut | Substantive comment  |   |
|          | Table 1   | crop application      | that will be         |   |
|          | Almond,   | methods should be     | addressed after      |   |
|          | Pistachio | corrected to C, BT,   | public comment has   |   |
|          |           | IR, DS.               | been received.       |   |
|          |           |                       |                      |   |
|          |           | For the DF, revise    |                      |   |
|          |           | the information to    |                      |   |
|          |           | separate use patterns |                      |   |
|          |           | for Almonds from      |                      |   |
|          |           | Pistachios. Almond    |                      |   |
|          |           | use should read as it |                      |   |
|          |           | now stands in the     |                      |   |
|          |           | section, but for      |                      |   |
|          |           | Pistachios the        |                      |   |
|          |           | information should    |                      |   |
|          |           | read: App Rate 4, No  |                      |   |
|          |           | App 1, App Interval   |                      |   |
|          |           | NA, Max Load 4.       |                      |   |
|          |           |                       |                      |   |
|          |           | Add information for   |                      |   |
|          |           | the FlC to include    |                      |   |
|          |           | all nuts (Almond,     |                      |   |
|          |           | Pecan, Filbert,       |                      |   |
|          |           | Pistachio, Walnut),   |                      |   |
|          |           | as follows: Max App   |                      |   |
|          |           | Rate 4, No App 1, App |                      |   |
|          |           | Interval NA, Max Load |                      |   |
|          |           | 4, App Method C, BT,  |                      |   |
|          |           | IR, DS.               |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 10-13,    | Correct the           | Substantive comment  |   |
|          | Berries   | application methods   | that will be         |   |
|          | and Small | to BT, C, IR, DS      | addressed after      |   |
|          | Fruit     | unless as specified   | public comment has   |   |
|          |           | for individual crops. | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 10-13,    | For the DF            | Substantive comment  |   |
|          | Blueberry | formulation, change   | that will be         |   |
|          |           | No. App to 1 and Max  | addressed after      |   |
|          |           | load to 4.            | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11,       | Correct application   | Substantive comment  |   |
|          | S         | methods to BT, IR,    | that will be         |   |
|          | trawberry | DS, C for             | addressed after      |   |
|          |           | [all]{.underline}     | public comment has   |   |
|          |           | formulations.         | been received.       |   |
|          |           |                       |                      |   |
|          |           | Add a row for the EC  |                      |   |
|          |           | formulation, as       |                      |   |
|          |           | follows:              |                      |   |
|          |           |                       |                      |   |
|          |           | Max App 4, No. App.   |                      |   |
|          |           | NS, App Interval NS,  |                      |   |
|          |           | Max Load NS.          |                      |   |
|          |           |                       |                      |   |
|          |           | For the DF            |                      |   |
|          |           | formulation, change   |                      |   |
|          |           | No. App. to 1, change |                      |   |
|          |           | App Interval to NA,   |                      |   |
|          |           | change Max Load to 4. |                      |   |
|          |           |                       |                      |   |
|          |           | Add a row for the FlC |                      |   |
|          |           | formulation as        |                      |   |
|          |           | follows: Max App 1,   |                      |   |
|          |           | No App 1, App         |                      |   |
|          |           | Interval NA, Max Load |                      |   |
|          |           | 4.                    |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11,       | For 15 lb ai/A,       | Substantive comment  |   |
|          | Cr        | change No. App. to 1, | that will be         |   |
|          | anberries | change App Interval   | addressed after      |   |
|          |           | to NA, change Max     | public comment has   |   |
|          |           | Load to 15. Note that | been received.       |   |
|          |           | this is not the most  |                      |   |
|          |           | representative use    |                      |   |
|          |           | rate in cranberries   |                      |   |
|          |           | (see comments under   |                      |   |
|          |           | "A. Potential Risks   |                      |   |
|          |           | to Non-target         |                      |   |
|          |           | Non-endangered        |                      |   |
|          |           | Organisms" in this    |                      |   |
|          |           | table).               |                      |   |
|          |           |                       |                      |   |
|          |           | Change the            |                      |   |
|          |           | application method    |                      |   |
|          |           | for the Granular      |                      |   |
|          |           | formulation to A, B,  |                      |   |
|          |           | IR, G.                |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11,       | Change No. App. to 1, | Substantive comment  |   |
|          | Currants  | change App Interval   | that will be         |   |
|          |           | to NA, change Max     | addressed after      |   |
|          |           | Load to 4.            | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11,       | Separate Asparagus    | Substantive comment  |   |
|          | Brassica  | from other listed     | that will be         |   |
|          | and Leafy | vegetables.           | addressed after      |   |
|          | V         |                       | public comment has   |   |
|          | egetables | New row for Asparagus | been received.       |   |
|          |           | should contain the    |                      |   |
|          |           | following information |                      |   |
|          |           | for the DF            |                      |   |
|          |           | formulation: Max App  |                      |   |
|          |           | 4, No. App. 1, App    |                      |   |
|          |           | Interval NS, Max Load |                      |   |
|          |           | 4.                    |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the           |                      |   |
|          |           | application methods   |                      |   |
|          |           | to BT, B, C, SI, IR   |                      |   |
|          |           | for all listed        |                      |   |
|          |           | Brassica and Leafy    |                      |   |
|          |           | Vegetables.           |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11,       | Remove Nectarines     | Substantive comment  |   |
|          | Citrus    | from this section and | that will be         |   |
|          |           | include in Stone      | addressed after      |   |
|          |           | Fruit, below.         | public comment has   |   |
|          |           |                       | been received.       |   |
|          |           | Add row for the FlC   |                      |   |
|          |           | formulation for all   |                      |   |
|          |           | citrus, as follows:   |                      |   |
|          |           | Max App Rate 4, No    |                      |   |
|          |           | App 1, App Interval   |                      |   |
|          |           | NA, Max Load 4.       |                      |   |
|          |           |                       |                      |   |
|          |           | Correct               |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | citrus application    |                      |   |
|          |           | methods to BT, DS, C, |                      |   |
|          |           | IR for                |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | formulations.         |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 11, Stone | Add a row for the FlC | Substantive comment  |   |
|          | Fruit     | formulation as        | that will be         |   |
|          |           | follows: Max App Rate | addressed after      |   |
|          |           | 4, No App 1, App      | public comment has   |   |
|          |           | Interval NA, Max Load | been received.       |   |
|          |           | 4.                    |                      |   |
|          |           |                       |                      |   |
|          |           | Correct               |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | application methods   |                      |   |
|          |           | to BT, DS, C, IR for  |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | formulations.         |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12,       | Add a row for the FlC | Substantive comment  |   |
|          | Apple,    | formulation, as       | that will be         |   |
|          | Pear      | follows:              | addressed after      |   |
|          |           |                       | public comment has   |   |
|          |           | Max App Rate 4, No    | been received.       |   |
|          |           | App 1, App Interval   |                      |   |
|          |           | NA, Max Load 4.       |                      |   |
|          |           | Correct               |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | application methods   |                      |   |
|          |           | for Pome Fruit to BT, |                      |   |
|          |           | DS, C, IR for         |                      |   |
|          |           | [all]{.underline}     |                      |   |
|          |           | formulations.         |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12,       | Correct application   | Substantive comment  |   |
|          | Eggplant  | methods for all       | that will be         |   |
|          |           | Fruiting Vegetables   | addressed after      |   |
|          |           | to BT, C, SI, IR.     | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12,       | Correct application   | Substantive comment  |   |
|          | Pepper    | methods for all       | that will be         |   |
|          | and       | Fruiting Vegetables   | addressed after      |   |
|          | Tomato    | to BT, C, SI, IR for  | public comment has   |   |
|          |           | all formulations.     | been received.       |   |
|          |           |                       |                      |   |
|          |           | Add a row for the DF  |                      |   |
|          |           | formulation, as       |                      |   |
|          |           | follows:              |                      |   |
|          |           |                       |                      |   |
|          |           | Max App Rate 2, No    |                      |   |
|          |           | App NS, App Interval  |                      |   |
|          |           | NS, Max Load 2.       |                      |   |
|          |           |                       |                      |   |
|          |           | Add a row for the FlC |                      |   |
|          |           | formulation, as       |                      |   |
|          |           | follows:              |                      |   |
|          |           |                       |                      |   |
|          |           | Max App Rate 2, No    |                      |   |
|          |           | App 1, App Interval   |                      |   |
|          |           | NA, Max Load 2.       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12, Other | For the DF row,       | Substantive comment  |   |
|          | V         | change No App to 1,   | that will be         |   |
|          | egetables | change App Interval   | addressed after      |   |
|          |           | to NA, and change Max | public comment has   |   |
|          |           | Load to 4. Correct    | been received.       |   |
|          |           | application methods   |                      |   |
|          |           | to BT, C, SI, IR.     |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12,       | Correct the spelling  | Spelling corrected   |   |
|          | Tropical  | of Avocado.           | in document.         |   |
|          | Fruits    |                       |                      |   |
|          |           | Correct application   | Substantive comment  |   |
|          |           | methods to BT, DS, C, | that will be         |   |
|          |           | IR for all            | addressed after      |   |
|          |           | formulations.         | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12,       | Add a row for the G   | Substantive comment  |   |
|          | Tobacco   | formulation, as       | that will be         |   |
|          |           | follows:              | addressed after      |   |
|          |           |                       | public comment has   |   |
|          |           | Max App Rate 1.4, No  | been received.       |   |
|          |           | App NS, App Interval  |                      |   |
|          |           | NS, Max Load unknown. |                      |   |
|          |           |                       |                      |   |
|          |           | Correct application   |                      |   |
|          |           | methods to B, BT, SI, |                      |   |
|          |           | IR for all            |                      |   |
|          |           | formulations.         |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 12, Sweet | For the DF row change | Substantive comment  |   |
|          | Potato    | No. App to 1, change  | that will be         |   |
|          |           | App Interval to NA,   | addressed after      |   |
|          |           | and change Max Load   | public comment has   |   |
|          |           | to 2.                 | been received.       |   |
|          |           |                       |                      |   |
|          |           | Correct application   |                      |   |
|          |           | methods to BT, B, SI, |                      |   |
|          |           | IR.                   |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 13, Mint  | For the DF row,       | Substantive comment  |   |
|          |           | change No. App to 1,  | that will be         |   |
|          |           | change App Interval   | addressed after      |   |
|          |           | to NA, and change Max | public comment has   |   |
|          |           | Load to 4.            | been received.       |   |
|          |           |                       |                      |   |
|          |           | Correct application   |                      |   |
|          |           | methods to B, IR for  |                      |   |
|          |           | all formulations.     |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 13, Olive | Correct application   | Substantive comment  |   |
|          |           | methods to BT, DS, C, | that will be         |   |
|          |           | IR.                   | addressed after      |   |
|          |           |                       | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 13,       | Add DF uses from EPA  | Substantive comment  |   |
|          | Trees/Orn | Reg. No. 70506-38.    | that will be         |   |
|          | amentals, |                       | addressed after      |   |
|          | Ground    | Add FlC uses from EPA | public comment has   |   |
|          | Covers,   | Reg. No. 70506-37.    | been received.       |   |
|          | H         |                       |                      |   |
|          | erbaceous | Correct application   |                      |   |
|          | pla       | methods for Shade     |                      |   |
|          | nts/woody | Trees, Ground cover,  |                      |   |
|          | shru      | Herbaceous plants to  |                      |   |
|          | bs/vines, | G, BT, SI, SB, DS, IR |                      |   |
|          | lawns and | for all formulations. |                      |   |
|          | turf,     |                       |                      |   |
|          | potting   | Correct application   |                      |   |
|          | soil      | methods for turf to   |                      |   |
|          |           | B, DS, IR, G for all  |                      |   |
|          |           | formulations.         |                      |   |
+----------+-----------+-----------------------+----------------------+---+
|          | 13,       | Add FlC = Flowable,   | Substantive comment  |   |
|          | Footnotes | A=air. The registrant | that will be         |   |
|          |           | assumed that there    | addressed after      |   |
|          |           | was no difference     | public comment has   |   |
|          |           | between the           | been received.       |   |
|          |           | application methods   |                      |   |
|          |           | ST and BT, and B and  |                      |   |
|          |           | SB.                   |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 2\.      | 14, Table | The number of         | Substantive comment  |   |
| Overview | 2         | applications to       | that will be         |   |
| of       |           | pecans should be 1    | addressed after      |   |
| P        |           | (based on UPI market  | public comment has   |   |
| esticide |           | research data).       | been received.       |   |
| Usage    |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 15, Table | Correct the vapor     | Vapor pressure,      |   |
| Chemical | 3         | pressure to 1.7 x     | Henry's Law, water   |   |
| and      |           | 10^-7^ mm at 25°C.    | solubility, soil     |   |
| Physical |           |                       | photolysis           |   |
| Pr       |           | Correct Henry's Law   | half-life, and       |   |
| operties |           | constant to 8.1x      | aqueous photolysis   |   |
|          |           | 10^-10^at 25°C.       | half-life values     |   |
|          |           |                       | will be corrected in |   |
|          |           | Correct the water     | document at this     |   |
|          |           | solubility to 74 at   | time. However,       |   |
|          |           | 25ºC (see comments to | correcting these     |   |
|          |           | "Napropamide RED      | input values in      |   |
|          |           | Product Chemistry     | modeling did not     |   |
|          |           | Considerations").     | change the estimates |   |
|          |           |                       | of exposure.         |   |
|          |           | Correct the soil      |                      |   |
|          |           | photolysis half life  |                      |   |
|          |           | to 28 days.           |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| a\. Fate | 16        | Correct the vapor     |                      |   |
| in the   |           | pressure to           |                      |   |
| Ter      |           | 1.7x10^-7^ mm.        |                      |   |
| restrial |           |                       |                      |   |
| Env      |           |                       |                      |   |
| ironment |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| a\. Fate | 16        | Correct Henry's Law   |                      |   |
| in the   |           | constant to           |                      |   |
| Aquatic  |           | 8.1x10^-10^           |                      |   |
| Env      |           | atm-m^3^/mole.        |                      |   |
| ironment |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| b\.      | 22,       | Correct the           |                      |   |
| Aquatic  | paragraph | laboratory data       |                      |   |
| Env      | 1         | half-life to 6.8      |                      |   |
| ironment |           | minutes.              |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| D. Key   | 27,       | Correct the aqueous   |                      |   |
| Uncer    | second    | photolysis half-life  |                      |   |
| tainties | bullet,   | to 6.8 minutes.       |                      |   |
| and      | third     |                       |                      |   |
| Inf      | bullet    |                       |                      |   |
| ormation |           |                       |                      |   |
| Gaps     |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 1\.      | 28,       | Correct the word      | Corrected in         |   |
| Specific | section   | "increased" to        | document at this     |   |
| Consid   | 1.d       | "increase".           | time.                |   |
| erations |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 2\.      | 30        | Paragraph 1: delete   | Corrected in         |   |
| Planned  |           | the reference to WP.  | document at this     |   |
| Analysis |           |                       | time.                |   |
|          |           | Paragraph 2: change   |                      |   |
|          |           | "Devrinol G" to       | Corrected in         |   |
|          |           | "Devrinol 10G".       | document at this     |   |
|          |           |                       | time.                |   |
+----------+-----------+-----------------------+----------------------+---+
| a\. Fate | 33,       | Correct the vapor     | Vapor pressure and   |   |
| in the   | paragraph | pressure to           | Henry's Law values   |   |
| Ter      | 1         | 1.7x10^-7^ mm.        | will be corrected in |   |
| restrial |           |                       | document at this     |   |
| Env      |           |                       | time.                |   |
| ironment |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| a\. Fate | 34, third | Correct Henry's Law   |                      |   |
| in the   | paragraph | constant to           |                      |   |
| Aquatic  |           | 8.1x10^-10^           |                      |   |
| Env      |           | atm-m^3^/mole (based  |                      |   |
| ironment |           | on the correct vapor  |                      |   |
|          |           | pressure and water    |                      |   |
|          |           | solubility).          |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 35        | The information from  | EFED used best       |   |
| Aquatic  |           | NCFAP is almost 8     | available data from  |   |
| Resource |           | years old and not     | all sources.         |   |
| Exposure |           | accurate for the      |                      |   |
| As       |           | current use data for  |                      |   |
| sessment |           | napropamide. See      |                      |   |
|          |           | Section II.A. of this |                      |   |
|          |           | document for further  |                      |   |
|          |           | comments.             |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 36,       | Correct the           | Substantive comment  |   |
| Aquatic  | paragraph | assumption regarding  | that will be         |   |
| Resource | 2         | the 7 day application | addressed after      |   |
| Exposure |           | interval to 90 days.  | public comment has   |   |
| As       |           |                       | been received.       |   |
| sessment |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 36,       | Correct the model     | Substantive comment  |   |
| Aquatic  | paragraph | assumptions for       | that will be         |   |
| Resource | 4         | cranberries to        | addressed after      |   |
| Exposure |           | reflect the fact that | public comment has   |   |
| As       |           | herbicides are not    | been received.       |   |
| sessment |           | applied to a field    |                      |   |
|          |           | which is flooded 0-4  |                      |   |
|          |           | hours after           |                      |   |
|          |           | application.          |                      |   |
|          |           | According to Dr.      |                      |   |
|          |           | Hilary Sandler,       |                      |   |
|          |           | University of         |                      |   |
|          |           | Massachusetts         |                      |   |
|          |           | Cranberry Research    |                      |   |
|          |           | Station, fields are   |                      |   |
|          |           | not flooded for at    |                      |   |
|          |           | least 5 months after  |                      |   |
|          |           | a napropamide (or     |                      |   |
|          |           | other herbicide)      |                      |   |
|          |           | application. A copy   |                      |   |
|          |           | of the "Best          |                      |   |
|          |           | Management Practices  |                      |   |
|          |           | Guide for             |                      |   |
|          |           | Massachusetts         |                      |   |
|          |           | Cranberry Production" |                      |   |
|          |           | can be provided to    |                      |   |
|          |           | support this use      |                      |   |
|          |           | pattern.              |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 37-38,    | Header: correct the   | Proper application   |   |
| Aquatic  | Table 7   | kg/h units for        | amounts in kg/ha     |   |
| Resource |           | Application           | were used as inputs  |   |
| Exposure |           | Rate---the rates in   | into Table 7.        |   |
| Ass      |           | the table are in lb   |                      |   |
| essment, |           | ai/A.                 | Substantive comment  |   |
| Table 7  |           |                       | that will be         |   |
|          |           | Correct maximum       | addressed after      |   |
|          |           | application rates for | public comment has   |   |
|          |           | all crops to 4 (the   | been received.       |   |
|          |           | WP formulation        |                      |   |
|          |           | registration is       | Substantive comment  |   |
|          |           | cancelled) except for | that will be         |   |
|          |           | turf which is applied | addressed after      |   |
|          |           | at either 4 or 6 lb.  | public comment has   |   |
|          |           | ai/A.                 | been received.       |   |
|          |           |                       |                      |   |
|          |           | Under "Maximum No. of | Vapor pressure,      |   |
|          |           | Applications" for 1   | water solubility,    |   |
|          |           | application, delete   | and soil photolysis  |   |
|          |           | all but PA turf since | half-life will be    |   |
|          |           | there are no other    | corrected in         |   |
|          |           | uses at the 6 lb ai/A | document at this     |   |
|          |           | rate. Under "Maximum  | time. However,       |   |
|          |           | No. of Applications"  | correcting these     |   |
|          |           | for two applications, | input values in      |   |
|          |           | delete OR, PA, NC     | modeling did not     |   |
|          |           | apples, GA pecan, and | change the estimates |   |
|          |           | FL citrus since the   | of exposure.         |   |
|          |           | labels only allow a   |                      |   |
|          |           | single application.   |                      |   |
|          |           | CA tomato and FL      |                      |   |
|          |           | pepper were not       |                      |   |
|          |           | included in the       |                      |   |
|          |           | modeling so these     |                      |   |
|          |           | should also be        |                      |   |
|          |           | deleted.              |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the model     |                      |   |
|          |           | input to 90 day       |                      |   |
|          |           | application intervals |                      |   |
|          |           | for Western region    |                      |   |
|          |           | crops only. Note that |                      |   |
|          |           | the granular may be   |                      |   |
|          |           | applied by air to     |                      |   |
|          |           | cranberries.          |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the vapor     |                      |   |
|          |           | pressure to           |                      |   |
|          |           | 1.7x10^-7^ mm at 25   |                      |   |
|          |           | °C. Correct the water |                      |   |
|          |           | solubility to 74 mg/L |                      |   |
|          |           | at 25 °C.             |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the           |                      |   |
|          |           | photolysis half-life  |                      |   |
|          |           | to 0.0047 days.       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 39, Table | Correct the time from | Substantive comment  |   |
| Aquatic  | 8         | application to        | that will be         |   |
| Resource |           | flooding to 135 days  | addressed after      |   |
| Exposure |           | (typical              | public comment has   |   |
| As       |           | ap                    | been received.       |   |
| sessment |           | plication-to-flooding |                      |   |
|          |           | dates range from      |                      |   |
|          |           | 120-150 days). The    |                      |   |
|          |           | typical application   |                      |   |
|          |           | dates for napropamide |                      |   |
|          |           | is from the end of    |                      |   |
|          |           | March to mid-April;   |                      |   |
|          |           | harvest is in         |                      |   |
|          |           | mid-September. Input  |                      |   |
|          |           | for cranberry model   |                      |   |
|          |           | from Dr. Hilary       |                      |   |
|          |           | Sandler, UMass        |                      |   |
|          |           | Amherst Cranberry     |                      |   |
|          |           | Research Station.     |                      |   |
|          |           | Copies of cranberry   |                      |   |
|          |           | BMP available upon    |                      |   |
|          |           | request.              |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the maximum   |                      |   |
|          |           | use rate to 9 since   |                      |   |
|          |           | the maximum use rate  |                      |   |
|          |           | of 15 is only for     |                      |   |
|          |           | muck soils in the PNW |                      |   |
|          |           | (WA and OR) and the   |                      |   |
|          |           | model does not model  |                      |   |
|          |           | this type of soil     |                      |   |
|          |           | (muck soils are high  |                      |   |
|          |           | in organic carbon     |                      |   |
|          |           | unlike the soil       |                      |   |
|          |           | modeled). Muck soils  |                      |   |
|          |           | represent less than   |                      |   |
|          |           | 3% of the total       |                      |   |
|          |           | cranberry acres in    |                      |   |
|          |           | the US.               |                      |   |
|          |           |                       |                      |   |
|          |           | Correct the aqueous   |                      |   |
|          |           | photolysis half-life  |                      |   |
|          |           | to 0.113 hr. (based   |                      |   |
|          |           | on the 6.8 min        |                      |   |
|          |           | half-life).           |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 3\.      | 40, Table | Correct all models    | Substantive comment  |   |
| Aquatic  | 9         | for maximum use rate  | that will be         |   |
| Resource |           | of 4 lb ai/A.         | addressed after      |   |
| Exposure |           |                       | public comment has   |   |
| As       |           |                       | been received.       |   |
| sessment |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| b\.      | 43, Table | The application       | Substantive comment  |   |
| Spray    | 11        | interval is 90 days,  | that will be         |   |
| Appl     |           | not 7 days and the    | addressed after      |   |
| ications |           | maximum use rate is 4 | public comment has   |   |
| and      |           | lbs ai/A.             | been received.       |   |
| Residues |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| 5\.      | 43-45,    | Correct model inputs  | Substantive comment  |   |
| No       | Tables    | to delete 6 lb ai/A   | that will be         |   |
| n-Target | 12, 13,   | scenarios.            | addressed after      |   |
| Plant    | 14        |                       | public comment has   |   |
| Exposure |           |                       | been received.       |   |
| Modeling |           |                       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Nap      | 46, Table | The footnote is       | EFED corrected       |   |
| ropamide | 15        | unclear since none of | statement: acute     |   |
| Toxicity |           | the fish acute        | toxicity \>1 mg/LH   |   |
| Ca       |           | toxicity tests        |                      |   |
| tegories |           | demonstrated acute    |                      |   |
|          |           | toxicity \< 1 mg/L.   |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Nap      | 47, Table | The accession number  | EFED agrees with     |   |
| ropamide | 16        | for acute toxicity    | comments and         |   |
| Toxicity |           | for mallard duck      | corrections will be  |   |
| Ca       |           | refers to other       | made.                |   |
| tegories |           | studies and the       |                      |   |
|          |           | appropriate MRIDs are |                      |   |
|          |           | 79548 and 79555. The  |                      |   |
|          |           | MRID for acute        |                      |   |
|          |           | toxicity for          |                      |   |
|          |           | laboratory rats is    |                      |   |
|          |           | not a valid number    |                      |   |
|          |           | and should be         |                      |   |
|          |           | corrected to 40362902 |                      |   |
|          |           | (for technical).      |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 49        | Paragraph 1: Correct  | Document was         |   |
| Es       |           | the last sentence     | corrected according  |   |
| timation |           | since                 | to the registrant's  |   |
| --       |           |                       | comment.             |   |
| Int      |           | Appendix G does not   |                      |   |
| egration |           | summarize the LOCs    | Substantive comment  |   |
| of       |           | used in the risk      | that will be         |   |
| Exposure |           | assessment. The       | addressed after      |   |
| and      |           | author might be       | public comment has   |   |
| Effects  |           | referring to Appendix | been received.       |   |
| Data     |           | E.                    |                      |   |
|          |           |                       | Substantive comment  |   |
|          |           | Paragraph 2: The use  | that will be         |   |
|          |           | patterns should be    | addressed after      |   |
|          |           | corrected since two   | public comment has   |   |
|          |           | applications are only | been received.       |   |
|          |           | allowed in the        |                      |   |
|          |           | Western region.       |                      |   |
|          |           |                       |                      |   |
|          |           | Paragraph 6: Correct  |                      |   |
|          |           | the interval between  |                      |   |
|          |           | applications for the  |                      |   |
|          |           | Western region from 7 |                      |   |
|          |           | days to 90 days.      |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 50, Table | None of the crop      | Substantive comment  |   |
| Es       | 18        | scenarios except turf | that will be         |   |
| timation |           | and ornamentals are   | addressed after      |   |
| --       |           | applied at 6 lb ai/A. | public comment has   |   |
| Int      |           | and these assessments | been received.       |   |
| egration |           | should be removed.    |                      |   |
| of       |           | The interval between  |                      |   |
| Exposure |           | applications should   |                      |   |
| and      |           | be corrected to 90    |                      |   |
| Effects  |           | days. The crop        |                      |   |
| Data     |           | scenarios with two    |                      |   |
|          |           | applications should   |                      |   |
|          |           | be deleted except for |                      |   |
|          |           | the Western region    |                      |   |
|          |           | scenarios \[i.e.,     |                      |   |
|          |           | delete FL citrus, PA  |                      |   |
|          |           | apple, NC apple, GA   |                      |   |
|          |           | pecan with two        |                      |   |
|          |           | applications of 4 lb  |                      |   |
|          |           | ai/A\].               |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 51, Table | A revised risk        | Substantive comment  |   |
| Es       | 19        | assessment should be  | that will be         |   |
| timation |           | conducted with        | addressed after      |   |
| --       |           | appropriate input     | public comment has   |   |
| Int      |           | parameters (see       | been received.       |   |
| egration |           | comments for Table 8) |                      |   |
| of       |           | and the RQs revised.  |                      |   |
| Exposure |           |                       |                      |   |
| and      |           | Correct the Note at   |                      |   |
| Effects  |           | the end of the        |                      |   |
| Data     |           | footnote section      |                      |   |
|          |           | which refers to Table |                      |   |
|          |           | 18---it should refer  |                      |   |
|          |           | to Table 10.          |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 51-52,    | None of the crop      | Substantive comment  |   |
| Es       | Table 20  | scenarios except turf | that will be         |   |
| timation |           | are applied at 6 lb   | addressed after      |   |
| --       |           | ai/A. and these       | public comment has   |   |
| Int      |           | assessments should be | been received.       |   |
| egration |           | removed. The interval |                      |   |
| of       |           | between applications  |                      |   |
| Exposure |           | should be corrected   |                      |   |
| and      |           | to 90 days. The crop  |                      |   |
| Effects  |           | scenarios with two    |                      |   |
| Data     |           | applications should   |                      |   |
|          |           | be deleted except for |                      |   |
|          |           | the Western region    |                      |   |
|          |           | scenarios \[i.e.,     |                      |   |
|          |           | delete FL citrus, PA  |                      |   |
|          |           | apple, NC apple, GA   |                      |   |
|          |           | pecan with two        |                      |   |
|          |           | applications of 4 lb  |                      |   |
|          |           | ai/A\].               |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 53, Table | None of the crop      | Substantive comment  |   |
| Es       | 21        | scenarios except turf | that will be         |   |
| timation |           | and ornamentals are   | addressed after      |   |
| --       |           | applied at 6 lb ai/A. | public comment has   |   |
| Int      |           | and these assessments | been received.       |   |
| egration |           | should be removed.    |                      |   |
| of       |           |                       | Footnote is already  |   |
| Exposure |           | Delete the crop       | in Table.            |   |
| and      |           | scenario "Aerial      |                      |   |
| Effects  |           | Airblast, Spray       |                      |   |
| Data     |           | Chemigation" since    |                      |   |
|          |           | only the 10G          |                      |   |
|          |           | formulation is        |                      |   |
|          |           | allowed to be applied |                      |   |
|          |           | by air and only to    |                      |   |
|          |           | cranberries.          |                      |   |
|          |           |                       |                      |   |
|          |           | The interval between  |                      |   |
|          |           | applications should   |                      |   |
|          |           | be corrected to 90    |                      |   |
|          |           | days. The crop        |                      |   |
|          |           | scenarios with two    |                      |   |
|          |           | applications should   |                      |   |
|          |           | be deleted except for |                      |   |
|          |           | the Western region    |                      |   |
|          |           | scenarios \[i.e.,     |                      |   |
|          |           | delete FL citrus, PA  |                      |   |
|          |           | apple, NC apple, GA   |                      |   |
|          |           | pecan with two        |                      |   |
|          |           | applications of 4 lb  |                      |   |
|          |           | ai/A\].               |                      |   |
|          |           |                       |                      |   |
|          |           | Footnote 1, found at  |                      |   |
|          |           | the end of the table, |                      |   |
|          |           | needs to be added to  |                      |   |
|          |           | the table.            |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 53        | The input parameters  | Substantive comment  |   |
| Es       |           | for TERRPLANT should  | that will be         |   |
| timation |           | be corrected so that  | addressed after      |   |
| --       |           | the orchard/vineyard  | public comment has   |   |
| Int      |           | rate is 4 lb ai/A and | been received.       |   |
| egration |           | the interval between  |                      |   |
| of       |           | applications          |                      |   |
| Exposure |           | corrected from 7 to   |                      |   |
| and      |           | 90 days. In addition, |                      |   |
| Effects  |           | the fact that in most |                      |   |
| Data     |           | cases (turf           |                      |   |
|          |           | excluded),            |                      |   |
|          |           | napropamide is        |                      |   |
|          |           | applied as a band     |                      |   |
|          |           | treatment such that   |                      |   |
|          |           | an entire acre is not |                      |   |
|          |           | treated is not taken  |                      |   |
|          |           | into account. Except  |                      |   |
|          |           | for mint, turf, and   |                      |   |
|          |           | cranberry,            |                      |   |
|          |           | napropamide is not    |                      |   |
|          |           | applied by air.       |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| A. Risk  | 54, Table | None of the crop      | Substantive comment  |   |
| Es       | 22        | scenarios except turf | that will be         |   |
| timation |           | and ornamentals are   | addressed after      |   |
| --       |           | applied at 6 lb ai/A. | public comment has   |   |
| Int      |           | and these assessments | been received.       |   |
| egration |           | should be removed.    |                      |   |
| of       |           | The interval between  | Footnote is already  |   |
| Exposure |           | applications should   | in Table.            |   |
| and      |           | be corrected to 90    |                      |   |
| Effects  |           | days. The crop        |                      |   |
| Data     |           | scenarios with two    |                      |   |
|          |           | applications should   |                      |   |
|          |           | be deleted except for |                      |   |
|          |           | the Western region    |                      |   |
|          |           | scenarios \[i.e.,     |                      |   |
|          |           | delete FL citrus, PA  |                      |   |
|          |           | apple, NC apple, GA   |                      |   |
|          |           | pecan with two        |                      |   |
|          |           | applications of 4 lb  |                      |   |
|          |           | ai/A\].               |                      |   |
|          |           |                       |                      |   |
|          |           | Footnote 1, found at  |                      |   |
|          |           | the end of the table, |                      |   |
|          |           | needs to be added to  |                      |   |
|          |           | the table.            |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 57        | Bullet 3: Correct the | Half-life was        |   |
| Des      |           | half-life to 6.8      | corrected in the     |   |
| cription |           | minutes.              | document.            |   |
| --       |           |                       |                      |   |
| Interp   |           | Bullet 4: Correct the | Substantive comment  |   |
| retation |           | statements after a    | that will be         |   |
| of       |           | reassessment of Fl    | addressed after      |   |
| Direct   |           | citrus and GA pecans  | public comment has   |   |
| Effects  |           | scenarios at a single | been received.       |   |
|          |           | application of 4 lb   |                      |   |
|          |           | a.i/A.                | Substantive comment  |   |
|          |           |                       | that will be         |   |
|          |           | Bullet 5: After the   | addressed after      |   |
|          |           | cranberry model is    | public comment has   |   |
|          |           | re-run with more      | been received.       |   |
|          |           | realistic input       |                      |   |
|          |           | parameters based on   | EFED will review the |   |
|          |           | discussions with Dr.  | data when it is      |   |
|          |           | Hilary Sandler, the   | submitted to the     |   |
|          |           | concentration cited   | Agency.              |   |
|          |           | should be corrected.  |                      |   |
|          |           | Based on the half     |                      |   |
|          |           | life in soil, it is   |                      |   |
|          |           | unlikely that water   |                      |   |
|          |           | will become           |                      |   |
|          |           | contaminated with     |                      |   |
|          |           | napropamide when      |                      |   |
|          |           | cranberry fields are  |                      |   |
|          |           | flooded 120-150 days  |                      |   |
|          |           | after the             |                      |   |
|          |           | application.          |                      |   |
|          |           |                       |                      |   |
|          |           | Bullet 6: Reports for |                      |   |
|          |           | some aquatic plant    |                      |   |
|          |           | species are available |                      |   |
|          |           | and will be           |                      |   |
|          |           | submitted.            |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 59        | Paragraph 1: The last | Substantive comment  |   |
| Des      |           | sentence should be    | that will be         |   |
| cription |           | revised after the     | addressed after      |   |
| --       |           | correct use pattern   | public comment has   |   |
| Interp   |           | (one application at 4 | been received.       |   |
| retation |           | lb ai/A) is included  |                      |   |
| of       |           | in the risk           |                      |   |
| Direct   |           | assessment.           |                      |   |
| Effects  |           |                       |                      |   |
|          |           | Paragraph 2: Correct  |                      |   |
|          |           | the use pattern for   |                      |   |
|          |           | orchards and          |                      |   |
|          |           | vineyards.            |                      |   |
|          |           |                       |                      |   |
|          |           | Paragraph 3: delete 6 |                      |   |
|          |           | lb ai/A as the        |                      |   |
|          |           | highest application   |                      |   |
|          |           | rate for food crop    |                      |   |
|          |           | uses.                 |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 60        | Second paragraph: The | Substantive comment  |   |
| Des      |           | first sentence should | that will be         |   |
| cription |           | be corrected to give  | addressed after      |   |
| --       |           | the correct use       | public comment has   |   |
| Interp   |           | pattern (one          | been received.       |   |
| retation |           | application at 4 lb   |                      |   |
| of       |           | ai/A). The chronic    |                      |   |
| Direct   |           | risk to mammals was   |                      |   |
| Effects  |           | carried out using the |                      |   |
|          |           | incorrect assumption  |                      |   |
|          |           | that the interval     |                      |   |
|          |           | between applications  |                      |   |
|          |           | in the Western region |                      |   |
|          |           | is 7 days; this       |                      |   |
|          |           | interval should be 90 |                      |   |
|          |           | days. The risk        |                      |   |
|          |           | assessment did not    |                      |   |
|          |           | take into             |                      |   |
|          |           | consideration the     |                      |   |
|          |           | fact that napropamide |                      |   |
|          |           | is most often applied |                      |   |
|          |           | by band application   |                      |   |
|          |           | such that an entire   |                      |   |
|          |           | acre is not treated.  |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 65        | Paragraph 1: the last | Document will be     |   |
| Des      |           | sentence is correct   | corrected at this    |   |
| cription |           | with the exception    | time.                |   |
| --       |           | that the 10G          |                      |   |
| Interp   |           | formulation can be    | Document will be     |   |
| retation |           | applied to            | corrected at this    |   |
| of       |           | cranberries by air.   | time.                |   |
| Direct   |           |                       |                      |   |
| Effects  |           | Bullet 2: Correct the | Substantive comment  |   |
|          |           | aqueous half-life to  | that will be         |   |
|          |           | 6.8 minutes.          | addressed after      |   |
|          |           |                       | public comment has   |   |
|          |           | Bullet 3: See         | been received.       |   |
|          |           | comments in Section   |                      |   |
|          |           | II.C. above.          | Substantive comment  |   |
|          |           |                       | that will be         |   |
|          |           | Bullet 4: the         | addressed after      |   |
|          |           | appropriate time      | public comment has   |   |
|          |           | between applications  | been received        |   |
|          |           | is 90 days, not 7.    |                      |   |
|          |           |                       | Substantive comment  |   |
|          |           | Bullet 5: Band        | that will be         |   |
|          |           | applications are      | addressed after      |   |
|          |           | appropriate for many  | public comment has   |   |
|          |           | crops. See Section    | been received        |   |
|          |           | II.B. above for       |                      |   |
|          |           | additional comments.  |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 66        | Bullet 1: Correct the | EFED used NC tobacco |   |
| Des      |           | first sentence since  | as a surrogate in    |   |
| cription |           | none of the labels    | the absence of other |   |
| --       |           | prohibit use on       | PRZM-EXAMS tobacco   |   |
| Interp   |           | tobacco in NC.        | scenarios.           |   |
| retation |           |                       |                      |   |
| of       |           | Bullet 6: Agronomic   | Substantive comment  |   |
| Direct   |           | factors are readily   | that will be         |   |
| Effects  |           | available from either | addressed after      |   |
|          |           | the cranberry grower  | public comment has   |   |
|          |           | associations or       | been received        |   |
|          |           | university personnel  |                      |   |
|          |           | involved with         | Document corrected   |   |
|          |           | cranberry production. | at this time.        |   |
|          |           |                       |                      |   |
|          |           | Bullet 8: correct the |                      |   |
|          |           | spelling of the word  |                      |   |
|          |           | "content".            |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| B. Risk  | 68        | Paragraph 1: Correct  | Document was         |   |
| Des      |           | the half-life to 6.8  | corrected.           |   |
| cription |           | minutes.              |                      |   |
| --       |           |                       | Substantive comment  |   |
| Interp   |           | Bullet 2: EFED should | that will be         |   |
| retation |           | conduct a review of   | addressed after      |   |
| of       |           | the open literature   | public comment has   |   |
| Direct   |           | from ECOTOX in case   | been received.       |   |
| Effects  |           | data are available to |                      |   |
|          |           | refine the risk       |                      |   |
|          |           | assessments.          |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | A-1,      | The MRID for          | Document was         |   |
| A        | Table     | accumulation in fish  | corrected.           |   |
|          |           | is missing and is     |                      |   |
|          |           | 39774. Footnote 2     |                      |   |
|          |           | should be corrected   |                      |   |
|          |           | to replace Syngenta   |                      |   |
|          |           | with United           |                      |   |
|          |           | Phosphorus.           |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | B-1-2,    | Inputs should be      | Substantive comment  |   |
| B        | Table B-1 | corrected for use     | that will be         |   |
|          |           | rates and application | addressed after      |   |
|          |           | interval.             | public comment has   |   |
|          |           |                       | been received        |   |
|          |           | The water solubility  |                      |   |
|          |           | is 74 mg/L at 25° C.  | Water solubility and |   |
|          |           |                       | the aqueous          |   |
|          |           | Correct the aqueous   | photolysis half-life |   |
|          |           | photolysis half-life  | were corrected in    |   |
|          |           | to 6.8 min.           | the document.        |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | B-3-46    | Comments were         | Correct input        |   |
| B        |           | previously noted      | parameters were      |   |
|          |           | regarding the input   | included in document |   |
|          |           | parameters for the    | but did not change   |   |
|          |           | PRZM-EXAMS modeling.  | the estimates of     |   |
|          |           |                       | exposure.            |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | B-44,     | The last sentence     | Document was         |   |
| B        | paragraph | refers to Table XXX   | corrected.           |   |
|          | 1         | and should be Table   |                      |   |
|          |           | B-2.                  |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | B-44,     | The last sentence     | Document was         |   |
| B        | paragraph | refers to Table YYY   | corrected.           |   |
|          | 2         | and should be Table   |                      |   |
|          |           | B-3.                  |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | Table B-3 | Application rate      | Substantive comment  |   |
| B        |           | should be 9 lb ai/A.  | that will be         |   |
|          |           |                       | addressed after      |   |
|          |           |                       | public comment has   |   |
|          |           |                       | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | C-1-3     | Comments were         | Substantive comment  |   |
| C        |           | previously noted      | that will be         |   |
|          |           | regarding the input   | addressed after      |   |
|          |           | parameters for the    | public comment has   |   |
|          |           | SCI-GROW modeling.    | been received.       |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix |           | The last page of what | Page number was      |   |
| D        |           | appears to be         | fixed.               |   |
|          |           | Appendix D is         |                      |   |
|          |           | paginated as E-1 but  | Redlining was        |   |
|          |           | labeled as Table D-1. | removed from the     |   |
|          |           |                       | document for public  |   |
|          |           | Highlighted           | comment.             |   |
|          |           | information in red    |                      |   |
|          |           | was blacked out in    | Registrant is        |   |
|          |           | the black and white   | referring to Table   |   |
|          |           | copy submitted to     | D.1. The MRIDs are   |   |
|          |           | registrant, making it | found in Table E.1.  |   |
|          |           | impossible to verify  |                      |   |
|          |           | the accuracy of the   |                      |   |
|          |           | information.          |                      |   |
|          |           |                       |                      |   |
|          |           | There are no MRIDs    |                      |   |
|          |           | associated with the   |                      |   |
|          |           | data and the          |                      |   |
|          |           | endpoints could not   |                      |   |
|          |           | be verified.          |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix |           | Pages should be       | Document was         |   |
| E        |           | repaginated.          | corrected.           |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-2,      | 71-1: the accession   | EFED agrees with the |   |
| E        | Table     | number is incorrect   | following comment:   |   |
|          |           | and should be MRID    |                      |   |
|          |           | 79548 and 79555       | 71-1: the accession  |   |
|          |           |                       | number is incorrect  |   |
|          |           | 71-2: The MRIDs       | and should be MRID   |   |
|          |           | 2005019, 2005025 and  | 79548 and 79555      |   |
|          |           | 2005026 are incorrect |                      |   |
|          |           | and not found in      | 71-2: In regards to  |   |
|          |           | NPIRS. One other MRID | MRIDs 2005019,       |   |
|          |           | for this guideline    | 2005025 and 2005026. |   |
|          |           | which should be added | The following        |   |
|          |           | is 41610202.          | corrections have     |   |
|          |           |                       | been made:           |   |
|          |           | 72-1: MRID 2005027 is |                      |   |
|          |           | not found in NPRIS.   | MRID 2005025 is      |   |
|          |           |                       | replaced with MRID   |   |
|          |           |                       | 25893                |   |
|          |           |                       |                      |   |
|          |           |                       | MRID 2005026 is      |   |
|          |           |                       | replaced with MRID   |   |
|          |           |                       | 25894                |   |
|          |           |                       |                      |   |
|          |           |                       | MRID 2005019 is      |   |
|          |           |                       | replaced with MRID   |   |
|          |           |                       | 49497 Additionally   |   |
|          |           |                       | the LC50 of this     |   |
|          |           |                       | study in this should |   |
|          |           |                       | be changed from 5600 |   |
|          |           |                       | ppm to \> 56,000     |   |
|          |           |                       | ppm.                 |   |
|          |           |                       |                      |   |
|          |           |                       | In response to the   |   |
|          |           |                       | comment: "One other  |   |
|          |           |                       | MRID for this        |   |
|          |           |                       | guideline which      |   |
|          |           |                       | should be added is   |   |
|          |           |                       | 41610202" EFED has   |   |
|          |           |                       | no record of this    |   |
|          |           |                       | MRID.                |   |
|          |           |                       |                      |   |
|          |           |                       | In response to the   |   |
|          |           |                       | comment "72-1: MRID  |   |
|          |           |                       | 2005027 is not found |   |
|          |           |                       | in NPRIS", this MRID |   |
|          |           |                       | is not listed in     |   |
|          |           |                       | Table E2.            |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-5,      | The accession number  | EFED agrees with     |   |
| E        | Table 1   | is not valid and the  | comment. Correction  |   |
|          |           | MRIDs should be 79548 | will be made.        |   |
|          |           | and 79555.            |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-5,      | The MRIDs 2005019,    | In response to       |   |
| E        | Table 2   | 2005025 and 2005026   | comment "The MRIDs   |   |
|          |           | are not valid. The    | 2005019, 2005025 and |   |
|          |           | MRID listed as 25894  | 2005026, the         |   |
|          |           | should be corrected   | corrections have     |   |
|          |           | to 125894. One        | been madents.        |   |
|          |           | additional study not  |                      |   |
|          |           | listed is a mallard   | In response to       |   |
|          |           | duck study 41610202.  | comment "The MRID    |   |
|          |           |                       | listed as 25894      |   |
|          |           |                       | should be corrected  |   |
|          |           |                       | to 125894". The      |   |
|          |           |                       | Agency records       |   |
|          |           |                       | indicate that MRID   |   |
|          |           |                       | 25894 is the correct |   |
|          |           |                       | number.              |   |
|          |           |                       |                      |   |
|          |           |                       | In response to       |   |
|          |           |                       | comment " One        |   |
|          |           |                       | additional study not |   |
|          |           |                       | listed is a mallard  |   |
|          |           |                       | duck study           |   |
|          |           |                       | 41610202", the       |   |
|          |           |                       | Agency will make the |   |
|          |           |                       | correction will be   |   |
|          |           |                       | made once the data   |   |
|          |           |                       | evaluation of the    |   |
|          |           |                       | study is located.    |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-6,      | The accession number  | The Agency agrees    |   |
| E        | Table 3   | 230602 is not valid   | with this comment.   |   |
|          |           | and should be         | The correction will  |   |
|          |           | 40362902.             | be made.             |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-7,      | The MRID 2005027 is   | The Agency agrees    |   |
| E        | Table 4   | not valid and should  | with this comment.   |   |
|          |           | be removed.           | The correction will  |   |
|          |           |                       | be made.             |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix | E-9,      | The accession number  | The Agency agrees    |   |
| E        | Table 7   | 229228 is not valid   | with this comment.   |   |
|          |           | for the listed        | The correction will  |   |
|          |           | species. The correct  | be made.             |   |
|          |           | MRID is 65360.        |                      |   |
+----------+-----------+-----------------------+----------------------+---+
| Appendix |           | Pages of this         | The Appendix G       |   |
| G        |           | appendix are numbered | should be labeled    |   |
|          |           | as part of Appendix   | Appendix F           |   |
|          |           | F.                    |                      |   |
+----------+-----------+-----------------------+----------------------+---+