BEE-spoke-data/govdocs1-by-extension huggingface dataset:
**Center for Scientific Review**

**Advisory Committee**

**AGENDA**

**May 8-9, 2000**

**National Institutes of Health**

**6701 Rockledge Drive**

**Rockledge 2 Building, Room 9100**

**Monday, May 8**

I. Call to Order and Opening Remarks Dr. Keith Yamamoto (8:30)

Approval of January Minutes

II\. CSR Update Dr. Ellie Ehrenfeld (8:40)

III\. Panel on Scientific Boundaries for Review Dr. Shu Chien (9:30)

Dr. Michael Martin

Discussants Dr. Richard Lifton

Dr. Raphael Pollock

BREAK (10:30)

IV\. Expanding the Scope of Review Topics and

Approaches Dr. Shu Chien (11:00)

Dr. Eileen Bradley

Dr. Christine Melchior

Dr. Jean Sipe

Discussants Dr. Tadataka Yamada

Dr. Gabriel Navar

LUNCH (12:00)

V. Periodic Review of Study Sections Dr. Leonard Epstein (1:30)

Dr. Keith Yamamoto

Dr. Arnold Revzin

Dr. Rona Hirschberg

Discussants Dr. James Kushner

Dr. Lucia Rothman-Denes

VI\. Fellowship Review Dr. Gabriel Navar (2:30)

Dr. Nancy Pearson

Discussants Dr. Karen Matthews

Dr. Susan Berget

BREAK (3:30)

VII\. Reviewer Workload Dr. Raphael Pollock (4:00)

Dr. Sherry Dupere

Discussants Dr. Michael Colvin

Dr. Susan Berget

Dr. Keith Yamamoto

ADJOURN (5:00)

**Tuesday, May 9**

VIII\. Qualifications for Study Section Members Dr. Michael Colvin
(8:30)

Dr. James Kushner

Discussants Dr. Karen Matthews

Dr. Raphael Pollock

IX\. Redefining Study Section Service Dr. Karen Matthews (9:15)

Dr. Tadataka Yamada

Dr. Joanne Fujii

Dr. Daniel McDonald

Discussants Dr. Raphael Pollock

Dr. Gabriel Navar

**BREAK** (10:00)

X. Promoting Best Practices Dr. Richard Lifton (10:30)

Dr. Alex Politis

Discussants Dr. Leonard Epstein

Dr. Lucia Rothman-Denes

XI\. Additional Issues, Plans for September

Meeting, and Concluding Remarks Dr. Keith Yamamoto (11:30)

ADJOURN (12:00)
> **[Corrections for Macugen Briefing Document (NDA
> 21-756).]{.underline}**
>
> **Page 18 of briefing document:**
>
> **Primary Efficacy Results -- PP population observed cases only--
> Study 1003**

+------------+--------+-----------+-----------+----------+-----------+
| **Number   |        | **0.3     | **1 mg**  | **3 mg** | **Sham**  |
| of         |        | mg**      |           |          |           |
| Patients   |        |           |           |          |           |
| (%)**      |        |           |           |          |           |
+------------+--------+-----------+-----------+----------+-----------+
| Res        | Month  | 122       | **131     | 122      | 120       |
| ponders^1^ | 3      | (87.8%)   | (92.9%)** | (86.5%)  | (82.8%)   |
|            |        |           |           |          |           |
|            |        | *N=139*   | *N= 141*  | *N= 141* | *N= 145*  |
+------------+--------+-----------+-----------+----------+-----------+
|            | Month  | **110     | **125     | 116      | 101       |
|            | 6      | (85.3%)** | (86.8%)** | (82.3%)  | (69.7%)   |
|            |        |           |           |          |           |
|            |        | *N= 129*  | *N= 144*  | *N= 141* | *N= 145*  |
+------------+--------+-----------+-----------+----------+-----------+
|            | Month  | **103     | 115       | 110      | 93 (66%)  |
|            | 9      | (78.3%)** | (79.9%)   | (79.1%)  |           |
|            |        |           |           |          | *N= 141*  |
|            |        | *N= 131*  | *N= 144*  | *N= 139* |           |
+------------+--------+-----------+-----------+----------+-----------+
|            | Month  | [98       | [105      | 90       | 82        |
|            | 12     | (73.7%    | (75.5%    | (66.7%)  | (58.6%)   |
|            |        | )]{.mark} | )]{.mark} |          |           |
|            |        |           |           | *N= 135* | *N= 140*  |
|            |        | [p=0.0    | [p=0.00   |          |           |
|            |        | 1]{.mark} | 5]{.mark} |          |           |
|            |        |           |           |          |           |
|            |        | *N= 133*  | *N= 139*  |          |           |
+------------+--------+-----------+-----------+----------+-----------+

> ^1^ Patients who lost \< 15 letters of vision. Note: Patients who lost
> \< 15 letters of vision from baseline to 54 weeks is the primary
> efficacy endpoint
>
> ^2^ 3 mg dose was omitted from statistical analysis prior to unmasking
> data

**Page 24 of briefing document:**

![](media/image1.wmf)

**Page 25 briefing document:**

![](media/image2.wmf)

**Page 34 briefing document:**

![](media/image3.wmf)
***Abstract:***

Undergraduate Study in Senegal and South Africa for Non-Traditional U.S.
Students

The African Studies Center and the Office Study Abroad at Michigan State
University in collaboration with Washington, D.C.-based Council for
Opportunity in Education, representing more than 900 universities and
colleges in the United States, will coordinate a program that will
facilitate twelve (12) U.S. undergraduates to study for a semester in
either Senegal or South Africa. The GPA will provide the opportunity for
twelve students from disadvantaged and non-traditional backgrounds to
study for a semester in Michigan State University-developed study abroad
programs at either the *Université Cheikh Anta Diop* in Senegal, or at
the *University of KwaZulu-Natal,* in South Africa.

The proposed GPA will take place in the spring semester (January-June)
2005 and is designed (i) to significantly expand participants knowledge
and understanding of the history, culture, society and contemporary
issues in Senegal or South Africa, (ii) to increase the participants'
understanding of global issues that impact the U.S. and countries in
Africa, (iii) to provide non-traditional U.S. college students the
opportunity to study in Africa by participating in a semester length
study abroad program, (iv) to heighten awareness and understanding of
Africa within some communities across the US, and (v) to strengthen
linkages with host institutions in Senegal and South Africa.

The proposed project will comprise of three phases: (a) Pre-departure
communication and planning and orientation at departure (September 2004
-- January 2005); (b) Semester length study abroad program in Senegal or
South Africa (January -- June 2005); and (c) Reentry activities (June --
Fall 2005).

Cynthia Felbeck Chalou, Project Director

Assistant Director\
Office of Study Abroad\
Michigan State University\
109 International Center\
East Lansing, MI 48824-1035\
Tel: (517) 432-4345\
Fax: (517) 432-2082\
E-mail: <chalouc@msu.edu>
\(14\)

\[ACT OF MAY 19, 1828\]

Continuing the Mint at Philadelphia, and for other purposes.

SECTION 1. Continues the Mint at Philadelphia until

otherwise provided by law.

SEC. 2. Establishes the brass toy weight procured in

1827 as the standard troy pound of the Mint.

SEC. 3. Provides that the Director of the Mint shall pro-

cure a series of weights, requisite subdivisions and mul-

tiples of this pound weight, and that all transfers of the

Mint shall be regulated by this standard, to be tested an-

nually in the presence of the Assay Commissioners.

SEC. 4. *And be it further enacted,* That when silver bul-

lion, brought to the Mint for coinage, is found to require

the operation of the test, the expense of the materials em-

ployed in the process, together with a reasonable allowance

for the wastage necessarily arising therefrom, to be deter-

minded by the melter and refiner of the Mint, with the appro-

bation of the Director, shall be retained from such deposit,

and accounted for by the treasurer of the Mint to the Treas-

ury of the United States.

SEC. 5. *And be it further enacted,* That, when silver bul-

lion, brought to the Mint for coinage, shall be found to con-

tain a proportion of gold, the separation thereof shall be

effected at the expense of the party interested therein:

*Provided, nevertheless,* That, when the proportion of gold is

such that it cannot be separated advantageously, it shall

be lawful, with the consent of the owner, or, in his absence,

at the discretion of the Director, to coin the same as an or-

dinary deposit of silver.

SEC. 6. Authorizes employment of clerks and other force.

SEC. 7. *And be it further enacted,* That it shall be lawful

for the Director of the Mint to receive, and cause to be as-

sayed, bullion not intended for coinage, and to cause cer-

tificates to be given of the fineness thereof by such officer

as he shall designate for that purpose, at such rates of

charge, to be paid by the owner of said bullion, and under

such regulations, as the said Director may, for time to

time, establish.
***Luke Day and Daniel Shays to Springfield Court, Dec. 26^th^, 1786***

NORTHAMPTON, January 3.

The Court of General Sessions of the Peace and the Court of Common
Pleas, by a late resolve of the General Court, were directed to be
holden at Springfield, on the 26th ulta. In the morning of that day, a
number of armed men took possession of the ground near the Court-House
with an avowed design to prevent the Justices from entering the houses.
A Committee from the insurgents waited on the Justices with a request,
that the Courts might not be opened, and intimations were given that
very disagreeable consequences would follow in case of non compliance
and sentinels were placed at the door of the room where the Justices had
assembled. As no Jurors had been summoned, and no business was proposed
to be done, if there had been no opposition, except choosing a Clerk,
and as no force had been collected or attempted to be collected to
support the Courts, the Justices present thought it prudent and
necessary to inform the said Committee, that the Courts would not be
opened at that time. The Committee requested an answer in writing; the
Justices informed them, if they expected a written answer, they must
exhibit their request in writing; they retired and soon after produced
their written request, of which the following is a copy:

\"Springfield, Dec. 26, 1786.\
\"WE request the Hon. Judges of this Court, not to open said Court at
this term nor do any kind of business whatever, but all kinds of
business remain as though no such Court had been appointed.\
LUKE DAY\
DANIEL SHAYS,\
THOMAS GROVER\"

To which the following answer was returned:\
\"Springfield, Dec 26, 1786.\
\"THE Justices of the Court of Common Pleas and Court of General
Sessions of the Peace, now assembled at Springfield, in consideration of
the opposition made to the opening the said Courts, have determined not
to do any business, or open the said Courts at this term.\
\"ELEAZER PORTER.\"\
Soon after which the insurgents, amounting, as was supposed, to about
300, quietly dispersed.

**HAMPSHIRE GAZETTE, Jan. 3^rd^, 1787, #L04.073**

**Memorial Libraries, Deerfield, MA**
Computer Science

**ENHANCING A VIRTUAL REALITY SIMULATOR OF THE ENIAC**

John Glover, Computer Science Department, DePauw University,
johnglover_2009@depauw.edu

LaVaughn Johnson, DePauw University, Computer Science Department,
Greencastle, IN, 46135, dharms@depauw.edu

In 1943, Dr. John Mauchly and. J. Pres Eckert of the University of
Pennsylvania's Moore School of Electrical Engineering developed the
ENIAC computer to calculate firing tables of artillery shells. The ENIAC
(Electronic Numerical Integrator and Computer) is considered the first
fully implemented electronic programmable computer. Unlike computers of
today it was programmed manually through dials, switches, and cables.
Though it only took few seconds to do the necessary calculations to
solve a problem, the computer operators often spent 2 or more days
programming it.

Our work extended a virtual reality simulator of the ENIAC that was
developed by Dr. Harms and a team of REU students in 2003. The simulator
runs on a Fedora Linux computer and is written in C++ using the openGL
graphics library and the openGL Utility Toolkit (GLUT).

We extended the simulator in four ways: 1) we implemented the high speed
multiplier unit, 2) we improved the graphical environment, 3) we
implemented the ability to save the current configuration of the ENIAC,
and 4) we incorporated the use of menus to change the ENIAC
configuration.

Our simulation creates a virtual 3D room to fit the large ENIAC instead
of just a flat visualization. The 3-D version equips the simulation with
depth and a realistic look. Through a user's hands-on experience with
the simulation, we hope to produce a model for learning about the
ENIAC's function, programming, and relativity to today's computers.

Our process of implementing designs and functionality depended on
finding the correct and most accurate documentation of the individual
units. Circuitry diagrams and the original ENIAC patent helped us the
most in our efforts. While adapting the original ENIAC units to our
virtual simulator, we changed the operations within some of them to
coincide with the work previously done by other REU groups. For example,
instead of running the virtual simulator on clock speed to cycle through
operations, each of the ENIAC unit's run on a 4 cycle process.

During the summer we implemented the multiplier unit, capable of
multiplying two ten digit numbers and outputting a product of 20 digits,
improved the graphical appearance on the previous units by adding status
lights, covers under the cabinets, and redecorated the room walls. We
also added GLUT menus to the interface and implemented a save feature.
Introducing the multiplier into the virtual ENIAC allows for more
complex programming which permits us to solve some actual problems
combined with the other units we have implemented already. The result of
our graphics work provides a fuller looking ENIAC room without as many
gaps and unfilled spaces, more functionality and capabilities. For the
simulation's interface to be more user-friendly we introduced the menus
to configure the ENIAC in real-time.
Frontiers in Tribology at the Atomic Scale

Mark Stevens, Sandia National Laboratories

Title: Chemical Effects on the Adhesion and Friction between Alkanethiol
Monolayers: Molecular Dynamics Simulations

Abstract:

The chemical effects on the adhesion and friction between alkanethiol
self-assembled monolayers (SAMs) on gold are studied using molecular
dynamics simulations. Alkanethiol SAMs (S(CH~2~)~n~X) are investigated
as a function of terminal group (X= CH~3~, CF~3~, OH and COOH) and chain
length *n*. The adhesive force is calculated as a function of the
separation between two SAMs with the same terminal group. The maximum
attraction is strong for the OH and COOH terminated SAMs which form
interlayer hydrogen bonds, and the adhesion-separation curves depend
strongly on *n*. The magnitude of the attractive minimum varies little
for OH terminated SAMs and the variation is also small for COOH
terminated SAMs once the odd:even effect is considered. The source of
the *n* dependence are structural changes within the SAMs. For
separations within the attractive region of the adhesion curve, the
interlayer hydrogen bond interactions pull the chains to a more upright
tilt angle than the equilibrium, single monolayer tilt angle. Longer
chains have more upright tilt angles for separations in the attractive
region. For COOH SAMs with *n* ≤ 13 the maximum adhesion is
significantly larger for odd *n* in comparison to even *n* -- 1. The
difference between even and odd cases decreases with *n*, and for *n* \>
13 the difference is smaller than our uncertainty. Friction simulations
between two SAMs with the same *n* show that the shear stress is
significantly larger for X=COOH than for CH~3~. In agreement with
experiment, the friction for CF~3~ terminated alkanethiols is larger
than that for CH~3~ terminated SAMs in spite of the lower surface energy
of the former.
**IN THE UNITED DISTRICT COURT**

**FOR THE NORTHERN DISTRICT OF ILLINOIS**

**EASTERN DIVISION**

**UNITED STATES OF AMERICA, )**

**)**

**Plaintiff, )**

**)**

**v. ) Civ. No. 58-C-1158**

**)**

**TRUE TEMPER CORPORATION, )**

**)**

**Defendant. )**

**\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
)**

# ORDER TERMINATING 1959 FINAL JUDGMENT

The Court having received the motion of True Temper Sports, Inc. (\"True
Temper\"), successor in interest to defendant True Temper Corporation,
for termination of the Final Judgment entered on August 20, 1959, in the
above-captioned matter (\"1959 Final Judgment\"), and the United States
having represented to the Court that it has no objection to the motion,
and notice of the motion having been published in the *Federal
Register*, *The Wall Street Journal*, and *Golf World*, and all
interested parties having been given an opportunity to submit comments
concerning the proposed termination of the 1959 Final Judgment, and the
Court having considered all papers and comments filed in connection with
this motion, and and the Court finding that it is in the public interest
to terminate the 1959 Final Judgment, it is

**ORDERED, ADJUDGED, AND DECREED:**

That said 1959 Final Judgment is hereby terminated.

Dated:\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

United States District Judge
**EXHIBIT B TO SC LBR 2081-2**

UNITED STATES BANKRUPTCY COURT

FOR THE DISTRICT OF SOUTH CAROLINA

+-----------------------------------+-----------------------------------+
| IN RE:                            | CASE NO:                          |
|                                   |                                   |
| Debtor(s).                        | CHAPTER:                          |
|                                   |                                   |
|                                   | CERTIFICATION REGARDING           |
|                                   |                                   |
|                                   | REFILED CASES                     |
+-----------------------------------+-----------------------------------+

The undersigned certifies the following pursuant to SC LBR 2081-2 and
subject to Fed. R. Bankr. P. 9011.

\(1\) The undersigned advises that the debtor has filed a previous
bankruptcy case in this District that has been dismissed, confirmed, or
otherwise closed within one (1) year of the filing of the
above-captioned case and that this filing constitutes a refiling for
that entity.

\(2\) The above-captioned debtor had previously filed a bankruptcy case
in this District, or currently has a pending bankruptcy case in this
District, as follows:

(Designate case numbers and date of filing).

\(3\) The undersigned recognizes that sanctions may be imposed for an
improper certification.

Date:\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_, \_\_\_\_\_\_
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

Signature of Attorney/*Pro Se* Debtor

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

Typed/Printed Name/Address/Telephone/

Facsimile/E-mail

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

District Court I.D. Number
**Reply to 2008 ESRL Global Monitoring Annual Conference**

I plan to attend ( ); I do not plan to attend ( ) the **ESRL Global
Monitoring Annual Conference** in Boulder, Colorado, on May 14 and May
15, 2008.

I would like to give a short (\~15 min) oral presentation ( ) or a
poster presentation ( ).

Proposed Title:

I am *uncertain at this time*; but please keep me on your list for
further information ( ).

Please take me off your mailing list ( ).

Name:

Address:

Telephone No.:

Fax No.:

E-mail address:

Return to: Misti Hinson

NOAA ESRL GMD

325 Broadway

Boulder, CO 80305-3328

Email: <Misti.Hinson@noaa.gov>

Fax: (303) 497-6546

You may send the information online at:

<http://www.esrl.noaa.gov/gmd/annualconference/reply.html>

Information about the meeting is at:

<http://www.esrl.noaa.gov/gmd/annualconference>

SAMPLE ABSTRACT

**Updated Trends for Halocarbons from Ground-Based Measurements**

[S.A. Montzka]{.underline}^1^, J.H. Butler^1^, T.M. Thompson^1^, G.S.
Dutton^2^, B.D. Hall^1^, J.A. Lind^2^, D.J. Mondeel^2^,\
and J.W. Elkins^1^

^1^NOAA Earth System Research Laboratory, 325 Broadway, Boulder, CO
80305;\
303-497-6657, Fax: 303-497-6290, E-mail: smontzka@noaa.gov

^2^Cooperative Institute for Research in Environmental Sciences,
University of Colorado, Boulder 80309

Chlorine and bromine from halocarbons catalyze the destruction of ozone
in the stratosphere. CMDL\'s measurements of anthropogenic halocarbons
show that while mixing ratios of chlorine have decreased since the early
1990s, bromine from halons continues to increase. The decrease in
chlorine has slowed recently owing to the lessening influence of methyl
chloroform, but growth rates of CFCs have continued to decline in recent
years; chlorine from aggregated CFCs was no longer increasing in 2000.
The gases used as CFC substitutes, the HCFCs, are no longer increasing
exponentially. Annual increases in chlorine from HCFCs have remained
fairly constant at about 10 ppt Cl yr^-1^ since the mid-1990s. Methyl
chloride and methyl bromide also transport a significant fraction of
halogen to the stratosphere, but have substantial natural sources. These
gases have exhibited significant interannual variability in recent years
because of variability in their natural sources. Global mixing ratios of
both of these methyl halides have decreased since 1998, but it is
difficult to conclude that the decreases in methyl bromide arise from
production restrictions in developed countries during recent years.

![](media/image1.wmf){width="5.75625in" height="3.7in"}

**Figure 1.** Earth System Research Laboratory measurements of
halocarbon mixing ratios from a combination of on-site instrumentation
and flask sampling techniques. The indicated curves are estimates of
global means at Earth's surface. For CH~3~Br and CH~3~Cl, thin curves
are global means and thick curves are 12-month running global means. The
gases shown represent over 90% of the chlorine and bromine transported
to the stratosphere in the form of long-lived gases.
Congressional Veteran Commendation

On behalf of a grateful nation and the citizens of the Twenty-Sixth
District of Texas, the Congressional Veteran Commendation is hereby
awarded to **Colonel Walter W. Pine** (U.S. Army/U.S. Air Force, Ret.)
for honorable service performed while a member of the Armed Forces of
the United States of America.

Colonel Walter Pine's patriotism, loyalty, and dedication to the United
States Air Force demonstrate the highest quality of service. Colonel
Pine volunteered for military service in 1941, graduating from flight
training in December 1944. He was recalled to active duty and served
honorably during the Korean War, flying C-47's in over 200 sorties into
Korean bases. Colonel Pine continued his decorated aviation career;
serving our nation in the Vietnam War, he flew the B-29 and transferred
to flying the Lockheed C-130. He was awarded the Silver Star for
gallantry in action against an enemy of the United States. This was one
of his many commendations for his bravery and meritorious service
including the Legion of Merit, Distinguished Flying Cross, Bronze Star,
Meritorious Service Medal, and a Presidential Unit citation. Serving
during World War II, the Korean War and the Vietnam War, Colonel Pine
dedicated 37 years of his life in service to the people of our great
country through his skill as a leader and pilot. Colonel Walter Pine
embodies the time honored history and patriotic spirit of the United
States Armed Services, and we are forever indebted to him for his long,
committed service to our nation.

His actions are consistent with the finest traditions of military
service and reflect great credit upon himself, the State of Texas, and
the United States of America.

> Signed under my hand this 11^th^ of this November 2008,
>
> [\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_]{.underline}
>
> Michael C. Burgess, M.D.
>
> Member of Congress
>
> Representing Texas' 26^th^ District
**[Summary of Modifications to 2008 Interim Guidelines]{.underline}**

*Overall*

Margins and spacing have been increased for better document readability.

The term 'transdisciplinary' is now used consistently in place of
'multi' and 'inter' - disciplinary.

The guidelines for application and review of consortia, previously
consolidated as separate sections, have been inserted into the relevant
individual components.

*Table of Contents*

A more detailed Table of Contents is included.

*Clarifications (previously posted on our website and distributed to
reviewers)*

Categories of Staff Investigator (i.e., Research v Clinical) and their
relevant criteria have been better defined (pages 20 and 51).

Specifics relevant to the application and review for Clinical and
Protocol Data Management Shared Resource, the Protocol Review and
Monitoring System, Data and Safety Monitoring, and Protocol Specific
Research Support have been added to the Guidelines (pages 32-36 and
53-54)

Text on minority accrual has been modified to reflect consideration of
all interventional trials in decisions relevant to approval (pages 40
and 54).

Application instructions and review criteria for the 2^nd^ stage
non-scientific review of comprehensiveness have been clarified (pages 40
and 55-56).

*Other Changes*

Standard language (paralleling that found in new National Cooperative
Group and SPORE guidelines) regarding consideration/reward for
participation/leadership in all types of clinical trials (including
cooperative group trials, etc.) has been incorporated (pages 8 and 52).

New application dates have been inserted (page 13).

Shared resource reporting criteria have been modified to request the top
75% of users, rather than 90% (page 30-31).

Templates provided for clinical study reporting have been modified to
eliminate sections not useful for review and provide greater clarity.
More explicit instructions have been added for their completion (pages
32-33 and 35).

*Peer Review*

Overall Quality of the Programs and Duration of Award have been
re-inserted as review criteria (pages 52 and 55).
03M03/29/06

S416-03M.doc

  -----------------------------------------------------------------------
  Use on projects when specifying Continuous Cold Recycled Asphalt Base
  Course.

  -----------------------------------------------------------------------

**Section 416. -- CONTINOUOUS COLD RECYCLED**

**ASPHALT BASE COURSE**

**Construction Requirements**

**416.08 Spreading, Finishing, and Compacting.**

**(a) Initial Compaction.**

> **(1) Type A.** [Delete the last sentence of the second paragraph and
> substitute the following:]{.underline}
>
> Measure the density of the inplace recycled mix according to ASTM D
> 2950.

**(d) Curing.**

> **(2) Recycled mix without quicklime.** [Delete the last sentence and
> substitute the following:]{.underline}
>
> Do not overlay until the moisture content of the recycled base is less
> than or equal to 1.5 percent according to ASTM D 2950 or until 21 days
> after recycling.

**Table 416-1 Sampling and Testing Requirements.** [Delete reference to
AASHTO T 310 in the Test Methods Specifications column, and substitute
ASTM D 2950.]{.underline}
[Highlights Video]{.underline}

The "Highlights video" is an 8-12 minute collection of some of the "best
of" video footage collected during the cruise, and other footage
representing signature segments of the mission. Generally, video clips
should not exceed one minute each, unless extended time is needed to
fully communicate an event of significant news interest. The tape should
be accompanied by a narrative description. "Wild sound," or natural
sound, especially the voices of excited scientists as they view a
discovery, may add to the news and public interest value of a particular
video clip, and so should be considered. Footage should include ROV
footage from any deep-sea discoveries, great general footage captured of
underwater resources investigated during the cruise (deep sea coral
community, shipwreck, hydrothermal vent, etc.), and any "first, deepest,
best," etc.

Additional footage should include:

-   The vessel

-   Primary technology deployment

-   A brief clip of the Chief Scientist stating where they are located
    and what they are doing. Objectives.

-   Great footage of the area being explored

-   Scientists at work

And might include:

-   Scenic footage of the surroundings

-   Students at work

-   Technicians at work

-   First look at samples brought on board

-   Ship's crew and/or science team working together

-   Incoming sonar data with specialist's explanation

-   Anything else weird and wonderful!

The most newsworthy video clip should be placed first on the MiniDV. The
highlights video should include a narrative description of each segment
(if not already included in the audio), and be output as a MiniDV tape.
A document containing the written narrative, and time codes for each
segment including a written description should be included with the
tape.

The video should be approved by the Web Coordinator, Chief Scientist and
any other contributing Videographer. A copy of the video should be
provided to the ship and a member of each Institution taking part in the
cruise. Ten additional copies (15 to 20 if significant news is involved)
should be made while on board and be ready to hand off to NOAA's Office
of Ocean Exploration and any requesting media venues when the Web
Coordinator steps off the ship.

**For More Information**

Fred Gorell, NOAA Office of Ocean Exploration  

Email: <fred.gorell@noaa.gov> 

Phone: (301) 713-9444 x181
**Map Finishing Certification**

**[SSAN here]{.underline} [STSSAID here]{.underline}**

Soil Survey Area Name STSSAID

# 

# Part I

1\. Map finishing was performed according to NRCS specifications as
described in the National Soil Survey Handbook (NSSH) Part 647, Soil Map
Development.

2\. A 100 percent edit has been completed.

I certify that these statements are true for the Soil Survey Area.

Digital Map Finishing Site Leader Date

# Part II

1\. The correlation document and amendments are current with the map
finished material.

2.  The soils data are derived from the Soil Survey Geographic Database.

3\. A 10 percent map finishing edit has been completed.

I certify that these statements are true for the Soil Survey Area.

MLRA Region 11 Team Leader Date
**[Olivet Nazarene University -- Master of Science in Nursing Degree:
Emergency Preparedness Disaster Readiness Track]{.underline}**

Olivet Nazarene University is offering a Master of Science in Nursing
Degree with an Emergency Preparedness Disaster Readiness Track. The
program is designed in the belief every nurse must have sufficient
knowledge and skill to recognize the potential for a mass casualty
incident, identify when such an event might occur, know how to protect
oneself, know how to provide immediate care for those individuals
involved, recognize their own role and limitations, and know where to
seek additional information and resources. The Master of Science in
Nursing with Emergency Preparedness Disaster Readiness Track is a
32-credit-hour program.

[Emergency Preparedness Disaster Readiness Track Required
Curriculum:]{.underline}

-   Emergency & Disaster Preparedness, Management and Nursing Education
    (4 credits)

-   Natural, Accident, Chemical, Biological & Radiological Disasters (4
    credits)

-   Emergency Preparedness Disaster Readiness Practicum (4 credits)

Olivet Nazarene University\'s Department of Nursing is accredited by the
Commission on Collegiate Nursing Education (CCNE) and the North Central
Association of Colleges and Schools.

For more information:

> Contact: Dr. Linda Davison, Chair
>
> Department of Nursing
>
> Olivet Nazarene University
>
> One University Avenue
>
> Box 6046
>
> Bourbonnais, IL 60914
>
> Ph: (815) 939-5340
>
> Fax: (815) 939-5383
>
> Email: <ldaviso@olivet.edu>
>
> Additional Information:
> [www.olivet.edu/academics/GCS/msn.asp](http://www.olivet.edu/academics/GCS/msn.asp).
>
> Additional Phone: Cathy McMullian: <cmcmulli@olivet.edu>; Ph: (815)
> 939-5340
>
> Update: 8/22/08

**"Please note: Some of the Web sites linked to in this document are not
federal government Web sites, and may not necessarily operate under the
same laws, regulations, and policies as federal Web sites."**
Topics to be covered in the accelerator physics section of the review:

Overview of separation method, achieved performance

Short summary of wiggler issues (specs, beam dynamics impact)

How to generate vertical dispersion bump

Scheme used

Magnet modifications

Beam dynamics impact

Measurements

Outstanding issues

> (aperture -- dispersion bump -- will simulate until review)
>
> long term 'stability' of dispersion

beamsize impact on other beamlines

How to minimize vertical emittance, spurious vertical dispersion

Measurements/Results

Relation to fs performance

ALS upgrade scenario -\> incompatibility (current/beamsize)!

Long term 'stability' of correction

Long+short term orbit stability (important for smaller beamsize)

How to maintain vertical beamsize stable everywhere if undulator is
scanning

Optimization possibilities

Use horizontal separation as well

Distribute dispersion bump between straight 5 and 6 (several unsolved
issues)

Insertion Device related issues (in vacuum PM/superconducting)

• Lifetime

> •Field Quality
>
> •Gap
>
> •Vacuum

• Injection Efficiency

> •Same as Lifetime

• Resistive Wall or HOM heating -\> how to split between me and Steve

• Impedance/Instability Thresholds -\> how to split between me and Steve

• Vacuum Issues (radiation/lifetime) -\> some remarks

• Radiation Damage -\> Steve, some remarks from me (collimation, ...)

• Performance -\> some remarks ?

• Cost -\> Steve

• Schedule -\> Steve

Chicane arrangement? Upgrade paths for beamline (EPU)? Space
considerations?

How to align undulator? (to stored beam or sliced beam)? What impact
does that have?

Split my talk into 2 or 3 ? Let Weishi and/or David give part of the
talk.
**Ford** is recalling 211,432 MY 2006 F-150 and Lincoln Mark LT pickup
trucks for failing to comply with either the requirements of Federal
Motor Vehicle Safety Standard (FMVSS) No. 105, \'Hydraulic And Electric
Brake Systems\' or FMVSS No. 135, \'Passenger Car Brake Systems.\' These
vehicles were built with a software error in the instrument cluster.
This error could prevent the antilock brake system (ABS) warning light
from illuminating if the ABS module ever became inoperative. Dealers
will recalibrate the instrument cluster in these vehicles. The recall is
expected to begin on February 15, 2006. 06V-033
**DA 08-2553**

**November 24, 2008**

**MM Docket No. 99-325**

**FILING DEADLINES EXTENDED**

**COMMENT SOUGHT ON JOINT PARTIES REQUEST**

**FOR FM DIGITAL POWER INCREASE AND**

**ASSOCIATED TECHNICAL STUDIES**

**Comment Date: December 5, 2008**

**Reply Comment Date: January 12, 2009**

By this Public Notice, the Media Bureau (Bureau) hereby extends the
filing deadline for comments on several recent filings in the pending
digital audio broadcasting proceeding, MM Docket No. 99-325.[^1] This
action is taken in response to a request from Media Access Project, on
behalf of Prometheus Radio Project.[^2] Interested parties may file
comments on or before December 5, 2008. The Bureau, on its own motion,
extends the filing deadline for reply comments to January 12, 2009.

For additional information, contact Susan Crawford, Ann Gallagher, or
Charles Miller of the Audio Division at (202) 418-2700.

**By: Chief, Media Bureau**

**-FCC-**

[^1]: *See* *Comment Sought on Joint Parties Request for FM Digital
    Power Increase and Associated Technical Studies,* Public Notice, DA
    08-2340 (rel. Oct. 23, 2008). *See also Digital Audio Broadcasting
    Systems and Their Impact on the Terrestrial Radio Broadcast
    Service*, Second Report and Order, First Order on Reconsideration
    and Second Further Notice of Proposed Rulemaking, 22 FCC Rcd 10,344
    (2007) (prior history omitted).

[^2]: *See* Motion for Extension of Time, Media Access Project, filed
    Nov. 21, 2008.
RFQ 1-057-RFJ.1326

Addenda to 52.212-1

INSTRUCTIONS TO OFFERORS: The offeror shall submit the following
information with its quote:

**Technical Information**:

Offerors shall submit technical data. Technical data, as a minimum shall
include the following: manufacturer's name, model and part number and
product specifications. Technical data may be in the form of product
brochures, advertisements, spec sheets etc. The technical data shall
readily identify how the proposed product complies with the government's
specifications.

This information shall be submitted in accordance with FAR 52.212-1 (d)
Product Samples.

**Past Performance Information:**

The offeror shall submit information identifying at least three (3)
references of whom it sold **similar** \[enter product description\] to
within the last three (3) years from the date of this request for quote
(RFQ). As a minimum, the reference information shall include the
following:

a.  Name of company or Federal, State or Local Government Agency

b.  Name of Point of Contact (POC), phone #, FAX \# and e-mail address

c.  Contract/Purchase Order number

d.  Date of Contract or Purchase Order and dollar value

e.  Brief description of items

Accuracy and Adequacy of Information:

The offeror is responsible for ensuring that the information required is
accurate and complete. The government may determine the offeror to be
non-responsive if the information provided is inaccurate or incomplete
to allow the Government to conduct a past performance or technical
evaluation.

ADDITIONAL INFORMATION:

\*\*\*[ADVANCE PAYMENTS ARE NOT AUTHORIZED]{.underline}. PAYMENT WILL BE
AUTHORIZED IN FULL 30 DAYS AFTER DELIVERY AND ACCEPTANCE.

REPRESENTATIONS AND CERTIFICATIONS MUST BE FILLED OUT AS INSTRUCTED.

PLEASE QUOTE FOB DESTINATION ONLY.

PLEASE PROVIDE A PUBLISHED PRICE LIST.
**\[DOE LETTERHEAD\]**

March 28, 2003

MEMORANDUM TO: EVERET H. BECKNER

> DEPUTY ADMINISTRATOR FOR DEFENSE PROGRAMS

JESSIE HILL ROBERSON

> ASSISTANT SECRETARY
>
> OFFICE OF ENVIRONMENTAL MANAGEMENT

FROM: ***BEVERLY A. COOK***

> ***ASSISTANT SECRETARY***
>
> ***OFFICE OF ENVIRONMENT, SAFETY AND HEALTH***

SUBJECT: Designation of Initial Safety Analysis "Tool Box Codes"

Commitment 4.2.1.1 of the Department's Implementation Plan for Defense
Nuclear Facilities Safety Board Recommendation 2002-1 is to "Identify
the codes used for safety analysis to be part of the Safety Analysis
Code Toolbox." The purpose of this memorandum is to document
identification of the initial list of codes.

The Safety Analysis Software Group conducted a detailed survey and
analysis to determine the codes that are widely used to support safety
basis documentation. The results of that analysis are documented in a
report titled, *Selection of Computer Codes for DOE Safety Analysis
Applications*, dated August 2002. This report can be found in the
Recommendation 2002-1 section of the Departmental Representative's web
page at https://www.doe.gov/deprep/. Based upon that report, the
following six codes have been selected as the initial safety analysis
toolbox codes:

-   Fire Source Term Code: CFAST

-   Leakpath Factor Code: MELCOR

-   Chemical Release/Dispersion and Consequence Codes: ALOHA and EPI
    code

-   Radiological Dispersion and Consequence Codes: MACCS2 and GENII

As stated in the Implementation Plan, additional work will be done to
bring these codes into compliance with new software quality assurance
requirements. Eventually these codes will be managed by a Central
Registry that will be designated in August 2003.

I would like to acknowledge the support you and your staff have
willingly provided in this area as we work to institutionalize the
Department's software quality assurance program. If you have any
questions concerning this matter, please call me or Ray Hardwick at
(202) 586-0307.

cc :

R. Card, US

D. Garman, EE-1

G. Staffo, EE-3C

R. Hardwick, EH-2

F. RUSSO, EH-3

P. Golan, EM-3

S. Johnson, EM-5

C. Smith, FE-1

C. Zamuda, FE-7

L. Brooks, NA-1

C. Przybylek, NA-1

J. Mangeno, NA-3.6

D. Crandall, NA-11

D. Beck, NA-12

K. Baker, NA-20

G. Rudy, NA-50

D. Miotla, NA-117

X. Ascanio, NA-124

W. Magwood, NE-1

R. Lange, NE-70

M. Chu, RW-1

R. Milner, RW-2E

R. Brown, RW-3

R. Orbach, SC-1

J. Decker, SC-2

M. Johnson, SC-3

L. Dever, SC-80

M. Whitaker, S-3.1

T. Wyka, S-3.1

I. Triay, CBFO

M. Gunn, CH

S. McCracken, FPO

D. Bergman-Tabbed, GJO

E. Sellers, ID & KCSO

R. Erickson, LASO

C. Yuan Soo Hoo, LSO

K. Carlson, NSO

G. Boyd, OR

B. Brumley, ORSO

R. Schepens, ORP

R. Warther, OH

D. Glenn, PSO

K. Klein, RL

E. Schmitt, RF

K. Boardman, SSO

J. Allison, SR

E. Wilmot, SRSO

A. Williams, WVO
### gDNA extractions from groundwater filters (7-13-05)

1.  Homogenize filter in whirl-pak bag by hand, making sure all filter
    surface is separated from sealing ring and is almost powder
    consistency.

2.  Add 1000 µL Miller phosphate buffer to bag, rinse down inside of bag
    to collect small filter dust particles.

3.  Using a wide bore pipette tip (cut tip with sterile scissors),
    collect buffer and filter material and transfer to a sterile 2 ml
    tube containing silica beads (0.3g of 0.5mm and 0.6g 0.1mm).

4.  Centrifuge tube at 16,000 x g for 2 min at 4^o^C and remove 700 μl
    of supernatant.

5.  Add 300µL Miller SDS lysis buffer.

6.  Add 300µL Phenol:Chloroform:Isoamyl alcohol (25:24:1). Invert tube
    several times to mix buffers and distribute silica beads.

7.  Shake tubes with Fast Prep machine for 30 seconds at speed 5.5 m/s.

8.  Centrifuge tubes at 16,000 x g for 5 minutes at 4^o^C.

9.  Transfer all aqueous supernatant to a 2.0 mL pre-spun phase-lok gel
    tube (Heavy).

10. Add an equal volume of chloroform and mix by hand inverting several
    times.

11. Centrifuge tubes at 16,000 x g for 3 minutes at 4^o^C.

12. Transfer upper phase to a new sterile 2 mL tube.

13. Add 2 volumes of MoBio solution S3 to tube.

14. Mix contents by inverting 20 times.

15. Load MoBio Spin Filter with up to 650µL and centrifuge 10,000 x g
    for 30 seconds. Discard the flow-through and repeat with remainder
    of mixture.

16. Add 300 µL Solution 4 to the filter and centrifuge 10,000 x g for 30
    seconds. Repeat this again.

17. Discard the flow-through and centrifuge again at 10,000 x g for 1
    min.

18. Carefully place spin filter in a new clean 2.0 mL tube. Avoid
    splashing any Solution S4 onto the spin filter.

19. Carefully add 50 µL sterile ddH~2~O to the center of the white
    filter membrane.

20. Centrifuge 30 seconds at 16,000 x g to elute the DNA.

21. Load the flow through back onto the same filter and centrifuge again
    for 30 seconds at 16,000 x g.

22. Store DNA at -20°C short term or -80^o^C long term.

This is a modification of the Miller Method:

Miller, D.N., Bryant, J.E., Madsen, E.L., and Ghiorse, W.C. 1999.
Evaluation and Optimization of DNA extraction and purification
procedures for soil and sediment samples. AEM 65:4715-4724.
Attachment 1

ORS FIP Justification Checklist

\$500,000 or less

Requisition \#

1\. **Is this a FIP request?** (ADP Hardware, ADP Software,
Telecommunications, ADP Maintenance, Support Services or Services)

2\. **Statement of Organization\'s Mission** (Background of the ICD and
Laboratory/Branch/Program function)

3\. **Explain the specific requirement that motivated this
acquisition.** What does the program need to accomplish in functional
terms?

4\. **What are the expected benefits of the acquisition?** What are you
doing now to meet the need, and how will this acquisition help you in
measurable ways, such as service delivery improvement, faster
throughput, etc.

5\. **What other alternatives were considered?**

6\. **Type and explanation of acquisition proposed.** (Competitive ‑
Open Market, Federal Supply Schedule, 8(a), Competitive 8a, Small
Business, or Non-competitive)

7\. **Is the equipment Energy Star compliant or is an exemption
required?**

8\. **Are there special FIP accommodation needs for persons with
disabilities?**

9\. **Have appropriate security and privacy requirements been met?**
+-------------+---------+------------+--------------+-----------------+
| # BUILDING  | *       | **FLOOR**  | **Sq. Ft.**  | **Drawing No.** |
|             | *WING** |            |              |                 |
+-------------+---------+------------+--------------+-----------------+
| 1           |         | 1          | 434          | FHP-1-1         |
+-------------+---------+------------+--------------+-----------------+
| 30          | L       | 1          | 953          | FHP-30-1L       |
+-------------+---------+------------+--------------+-----------------+
| 30          | L       | 3          | 4,279        | FHP-30-3L       |
+-------------+---------+------------+--------------+-----------------+
| 102         |         | 1          | 60           | FHP-102-1       |
+-------------+---------+------------+--------------+-----------------+
| 103         |         | 1          | 60           | FHP-103-1       |
+-------------+---------+------------+--------------+-----------------+
| 105         |         | 1          | 49           | FHP-105-1       |
+-------------+---------+------------+--------------+-----------------+
| 110         |         | 1          | 2,352        | FHP-110-1       |
+-------------+---------+------------+--------------+-----------------+
| 204         |         | 1          | 60           | FHP-204-1       |
+-------------+---------+------------+--------------+-----------------+
| 262         |         | 1          | 296          | FHP-262-1A-1    |
+-------------+---------+------------+--------------+-----------------+
| 305         |         | 1          | 60           | FHP-305-1       |
+-------------+---------+------------+--------------+-----------------+
| 324         |         | 1          | 416          | Not available   |
+-------------+---------+------------+--------------+-----------------+
| 420         |         | 1          | 1820         | FHP-420-1W      |
+-------------+---------+------------+--------------+-----------------+
| E139        |         | 1          | 57           | FHP-E139-1      |
+-------------+---------+------------+--------------+-----------------+
| E261        |         | 1          | 46           | FHP-E261-1      |
+-------------+---------+------------+--------------+-----------------+
| Building 30 |         | 1          | 60           | Not available   |
| parking lot |         |            |              |                 |
| guard house |         |            |              |                 |
| -South      |         |            |              |                 |
+-------------+---------+------------+--------------+-----------------+
| Building 30 |         | 1          | 60           | Not available   |
| parking lot |         |            |              |                 |
| guard house |         |            |              |                 |
| --North     |         |            |              |                 |
+-------------+---------+------------+--------------+-----------------+

**Hard Copies of the Facility Drawings are in the TRL.**