**Publications (John N. Weinstein, M.D., Ph.D.)**

1.  Weinstein, J.N., and Caplan, S.R.: Charge-mosaic membranes: Enhanced
    permeability and negative osmosis with a symmetrical salt.
    [Science]{.underline} 1968; 161: 70-72.

2.  Weinstein, J.N., Bunow, B., Yanowitz, I., and Caplan, S.R.: Water
    transport in charge-mosaic resin membranes. [Polymer
    Preprints]{.underline}. 1968; 9: 1564-1565.

3.  Weinstein, J.N., and Caplan, S.R.: Charge-mosaic membranes: Dialytic
    separation of electrolytes from nonelectrolytes and amino acids.
    [Science]{.underline} 1970; 169: 296-298.

4.  Weinstein, J.N., Bunow, B., and Caplan, S.R.: Transport properties
    of charge-mosaic membranes I. Theoretical considerations.
    [Desalination]{.underline} 1972; 11: 341-377.

5.  Gardner, C., Weinstein, J.N., and Caplan, S.R.: Transport properties
    of charge-mosaic membranes III. Piezodialysis.
    [Desalination]{.underline} 1973; 12: 19-33.

6.  Weinstein, J.N., and Caplan, S.R.: The definition of volume flow in
    the Kedem- Katchalsky description of membrane transport. [J. Phys.
    Chem.]{.underline} 1973; 77: 2710-2711.

7.  Weinstein, J.N., Kalif, D., and Caplan, S.R.: Transport properties
    of charge-mosaic membranes II. Experimental studies.
    [Desalination]{.underline} 1973; 12: 1-17.

8.  Weinstein, J.N., and Caplan, S.R.: [Charge-Mosaic
    Membranes.]{.underline} National Tech. Info. Service, Springfield,
    Va., 1974. INT-OSW-RDPR-74-987 (300 pages plus summaries).

9.  Weinstein, J.N., and Leitz, F.B.: Piezodialysis: A comparison of
    theoretical treatments. [Desalination]{.underline} 1975; 16:
    245-247.

10. Weinstein, J.N., and Leitz, F.B.: Electric power from differences in
    salinity: The dialytic battery. [Science]{.underline} 1976; 191:
    557-559.

11. Blumenthal, R., Weinstein, J.N., Sharrow, S.O., and Henkart, P.:
    Liposome-lymphocyte interactions: Saturable sites for transfer and
    intracellular release of liposome contents. [Proc. Natl. Acad.
    Sci.]{.underline} 1977; 74: 5603-5607.

12. Weinstein, J.N., Yoshikami, S., Henkart, P., Blumenthal, R., and
    Hagins, W.A.: Liposome-cell interaction: Transfer and intracellular
    release of a trapped fluorescent marker. [Science]{.underline} 1977;
    195: 489-492.

13. Blumenthal, R., Weinstein, J.N., and Henkart, P.: Lipid model
    membrane studies on immune cytotoxic mechanisms. In: Shamoo, A.E.
    and Miller, M.W. (Eds) Membrane Toxicity. New York: Plenum, 1977;
    495-507.

14. Pagano, R., and Weinstein, J.N.: Interactions of liposomes with
    mammalian cells. [Ann. Rev. Biophys. Bioeng.]{.underline} 1978; 7:
    435-468.

15. Yatvin, M.B., Weinstein, J.N., Dennis, W.H., and Blumenthal, R.: Use
    of hyperthermia to promote selective local release of drugs from
    liposomes. Proceedings of the Conference on Clinical. Prospects for
    Hypoxic Cell Sensitizers and Hyperthermia. Wisconsin, Madison
    Printing and Publishing Co., 1978; 105-112.

16. Weinstein, J.N., Blumenthal, R., Sharrow, S.O., and Henkart, P.:
    Antibody-mediated targeting of liposomes: Binding to lymphocytes
    without incorporation of vesicle contents into the cells. [Biochim.
    Biophys. Acta]{.underline} 1978; 509: 272-288.

17. Yatvin, M.B., Weinstein, J.N., Dennis, W.H., and Blumenthal, R.:
    Design of liposomes for enhanced local release of drugs by
    hyperthermia. [Science]{.underline} 1978; 202: 1290-1293.

18. Dragsten, P.R., Henkart, P., Blumenthal, R., Weinstein, J.N., and
    Schlessinger, J.: Lateral diffusion of surface immunoglobulin, Thy-l
    antigen, and a lipid probe in lymphocyte plasma membranes. [Proc.
    Natl. Acad. Sci.]{.underline} 1979; 76: 5163-5167.

19. Leserman, L.D., Weinstein, J.N., Blumenthal, R., Sharrow, S.O., and
    Terry, W.D.: Binding of antigen-bearing fluorescent liposomes to the
    murine myeloma tumor MOPC 3l5. [J. Immunol.]{.underline} 1979; 122:
    585-591.

20. Weinstein, J.N., Magin, R.L, Yatvin, M.B., and Zaharko, D.S.:
    Liposomes and local hyperthermia: Selective delivery of methotrexate
    to heated tumors. [Science]{.underline} 1979; 204: 188-191.

21. Wlodawer, A., Segrest, J.P., Chung, B.H., Chiovetti, R., Jr., and
    Weinstein, J.N.: High density lipoprotein recombinants: Evidence for
    a bicycle tire micelle structure obtained by neutron scattering and
    electron microscopy. [FEBS Letters]{.underline} 1979; 104: 231-235.

22. Blumenthal, R., Klausner, R.D., and Weinstein, J.N.:
    Voltage-dependent translocation of the asialoglycoprotein receptor
    across lipid membranes. [Nature]{.underline} 1980; 288: 333-338.

23. Leserman, L.D., and Weinstein, J.N: Receptor mediated binding and
    endocytosis of drug-containing liposomes by tumor cells. In: Tom,
    B.H., and Six, H.R. (Eds) Liposomes and Immunobiology. Amsterdam,
    Elsevier, 1980; 241-251.

24. Magin, R.L., and Weinstein, J.N.: Selective delivery of drugs in
    \"temperature-sensitive\" liposomes. In: Tom, B.H., and Six, H.R.
    (Eds) Liposomes and Immunobiology. Amsterdam, Elsevier, 1980;
    315-325.

25. Blumenthal, R., Klausner, R.D., Weinstein, J.N., Bridges, K.,
    Tsunoo, H., and Ashwell, G.: Voltage-dependent translocation of
    hepatic binding protein across lipid model membranes. [Annals N.Y.
    Acad. Sci.]{.underline} 1980; 358: 368-369.

26. Guo, L.S.S., Hamilton, R., Goerke, J., Weinstein, J.N., and Havel,
    R.J.: Interaction of unilamellar liposomes with serum lipoproteins
    and apolipoproteins. [J. Lipid Research]{.underline} 1980; 21:
    993-1003.

27. Klausner, R.L., Bridges, K., Tsunoo, H., Blumenthal, R., Weinstein,
    J.N., and Ashwell, G.: Reconstitution of the hepatic
    asialoglyco-protein receptor with phospholipid vesicles. [Proc.
    Natl. Acad. Sci.]{.underline} 1980; 77: 5087-5091.

28. Leserman, L.D., Barbet, J., Kourilsky, F.M., and Weinstein, J.N.:
    Liposomes directed to specific cellular targets by
    covalently-coupled monoclonal antibody, protein A, and avidin.
    [Nature]{.underline} 1980; 288: 602-604.

29. Leserman, L.D., Weinstein, J.N., Blumenthal, R., and Terry, W.D.:
    Receptor-mediated endocytosis of antibody-opsonized liposomes by
    tumor cells. [Proc. Natl. Acad. Sci.]{.underline} 1980; 77:
    4089-4093.

30. Leserman, L.D., Weinstein, J.N., Moore, J.J., and Terry, W.D.:
    Specific interaction of myeloma tumor cells with hapten-bearing
    liposomes containing methotrexate and carboxyfluorescein. [Cancer
    Research]{.underline} 1980; 40: 4768-4774.

31. Ralston, E., Blumenthal, R., Weinstein, J.N., Sharrow, S.O., and
    Henkart, P.: Lysophosphatidylcholine in liposomal membranes:
    Enhanced permeability but little effect on transfer of a
    water-soluble fluorescent marker into human lymphocytes. [Biochim.
    Biophys. Acta]{.underline} 1980; 597: 543-551.

32. Van Renswoude, A.J.B.M., Blumenthal, R., and Weinstein, J.N.:
    Thin-layer chromatography with agarose gels: A quick, simple method
    for evaluating liposome size. [Biochim. Biophys. Acta.]{.underline}
    1980; 595: 151-156.

33. Weinstein, J.N., Magin, R.L., Cysyk, R.L., and Zaharko, D.S.:
    Treatment of solid Ll2l0 murine tumors with local hyperthermia and
    temperature-sensitive liposomes containing methotrexate. [Cancer
    Research]{.underline} 1980; 40: 1388-1395.

34. Klausner, R.D., Kumar, N., Weinstein, J.N., Blumenthal, R., and
    Flavin, M.: Interaction of tubulin with phospholipid vesicles I:
    Association with vesicles at the phase transition. [J. Biol.
    Chem.]{.underline} 1981; 256: 5879-5885.

35. Kumar, N., Klausner, R.D., Weinstein, J.N., Blumenthal, R., and
    Flavin, M.: Interaction of tubulin with phospholipid vesicles II:
    Physical changes of the protein. [J. Biol. Chem.]{.underline} 1981;
    256: 5886-5889.

36. Parker, R.J., Sieber, S.M., and Weinstein, J.N.: The effect of
    liposome encapsulation of a fluorescent dye on its uptake by the
    lymphatics of the rat. [Pharmacology]{.underline} 1981; 23: 128-136.

37. Pitas, R.E., Innerarity, T.L., Weinstein, J.N., and Mahley, R.W.:
    Acetoacetylated lipoproteins used to distinguish fibroblasts from
    macrophages [in vitro]{.underline} by fluorescence microscopy.
    [Arteriosclerosis]{.underline} 1981; 1: 177-185.

38. Ralston, E., Hjelmeland, L.M., Klausner, R.D., Weinstein, J.N., and
    Blumenthal, R.: Carboxyfluorescein as a probe for liposome-cell
    interactions: Effect of impurities, and purification of the dye.
    [Biochim. Biophys. Acta]{.underline} 1981; 649: 133-137.

39. Weinstein, J.N.: Liposomes as \"targeted\" drug carriers: A physical
    chemical perspective. [Pure and Applied Chemistry]{.underline} 1981;
    53: 2241-2254.

40. Weinstein, J.N., Klausner, R.D., Innerarity, T.L., Ralston, E., and
    Blumenthal, R.: \"Phase transition release\", a new approach to the
    interaction of proteins with lipid vesicles: Application to
    lipoproteins. [Biochim. Biophys. Acta]{.underline} 1981; 647:
    270-284.

41. Yatvin, M.B., Muhlensiepen, H., Porschen, W., Weinstein, J.N., and
    Feinendegen, L.E.: Selective delivery of liposome encapsulated
    cis-dichlorodiammineplatinum (II) by heat: Influence on tumor drug
    uptake and growth. [Cancer Research]{.underline} 1981; 41:
    1602-1607.

42. Blumenthal, R., Klausner, R.D., and Weinstein, J.N.:
    Voltage-dependent changes in a membrane protein: Studies with the
    asialoglycoprotein receptor. [Biophysical Journal]{.underline} 1982;
    37: 122-124.

43. Magin, R.L., and Weinstein, J.N.: Delivery of drugs in
    temperature-sensitive liposomes. In: Gregoriadis, G., Senior, J.,
    and Trouet, A. (Eds) Targeting of Drugs. New York: Plenum, 1982;
    203-221.

44. Blumenthal, R., Ralston, E., Dragsten, P., Leserman, L.D., and
    Weinstein, J.N.: Lipid vesicle-cell interactions: Analysis of a
    model for transfer of contents from adsorbed vesicles to cells.
    [Membrane Biochemistry]{.underline} 1982; 4: 283-303.

45. Kempf, C., Klausner, R.D., Weinstein, J.N., van Renswoude, J.,
    Pincus, M., and Blumenthal, R.: Voltage-dependent transbilayer
    orientation of melittin. [J. Biol. Chem.]{.underline} 1982; 257:
    2469-2476.

46. Weinstein, J.N., Leserman, L.D., Henkart, P.A., and Blumenthal, R.:
    Antibody-mediated targeting of liposomes. In: Gregoriadis, G.,
    Senior, J., and Trouet, A. (Eds) Targeting of Drugs. New York:
    Plenum, 1982; 185-202.

47. Klausner, R.D., Berman, M., Blumenthal, R., Weinstein, J.N., and
    Caplan, S.R.: Compartmental analysis of light-induced proton
    movement in reconstituted bacteriorhodopsin vesicles.
    [Biochemistry]{.underline} 1982; 21: 3643-3650.

48. Kumar, N., Blumenthal, R., Henkart, M., Weinstein, J.N., and
    Klausner, R.D.: Aggregation and calcium-induced fusion of
    phosphatidylcholine vesicle-tubulin complexes. [J. Biol.
    Chem.]{.underline} 1982; 257: 15137-15144.

49. Weinstein, J.N., Leserman, L.D., Henkart, P.A., and Blumenthal, R.:
    Antibody-mediated targeting of liposomes. In: Gregoriadis, G.,
    Senior, J., and Trouet, A. (Eds) Targeting of Drugs. New York:
    Plenum, 1982; 185-202.

50. Weinstein, J.N., Blumenthal, R., Kempf, C., van Renswoude, J., and
    Klausner, R.D.: Charge clusters and the orientation of membrane
    proteins. [J. Membr. Biol.]{.underline} 1982; 66: 203-212.

51. Weinstein, J.N., Parker, R.J., Keenan, A.M., Dower, S.K., Morse,
    H.C., 3rd, and Sieber, S.M.: Monoclonal antibodies in the
    lymphatics: Toward the diagnosis and therapy of tumor metastases.
    [Science]{.underline} 1982; 218: 1334-1337.

52. Blumenthal, R., Kempf, C., van Renswoude, J., Weinstein, J.N., and
    Klausner, R.D.: Voltage-dependent orientation of membrane proteins.
    [J. Cell Biochem.]{.underline} 1983; 22: 55-67.

53. Klausner, R.D., van Renswoude, J., Kempf, C., Blumenthal, R., and
    Weinstein, J.N.: The folding of ovalbumin: Renaturation [in
    vitro]{.underline} versus biosynthesis [in vitro]{.underline}.
    [Biochem. J.]{.underline} 1983; 212: 801-810.

54. Miller, M., Weinstein, J.N., and Wlodawer, A.: Preliminary x-ray
    analysis of single crystals of ovalbumin and plakalbumin. [J. Biol.
    Chem.]{.underline} 1983; 258: 5864-5866.

55. Weinstein, J.N., Steller, M.A., Keenan, A.M., Covell, D.G., Key,
    M.E., Sieber, S.M., Oldham, R.K., Hwang, K.M., and Parker, R.J.:
    Monoclonal antibodies in the lymphatics: Selective delivery to lymph
    node metastases of a solid tumor. [Science]{.underline} 1983; 222:
    423-427.

56. Weinstein, J.N.: Liposomes as drug carriers in cancer therapy.
    [Cancer Treat. Reports, Twenty-fifth Anniversary Issue]{.underline}
    1984; 68: 127-135.

57. Weinstein, J.N., and Leserman, L.D.: Liposomes as drug carriers in
    cancer chemotherapy. [Pharmacology and Therapeutics]{.underline}
    1984; 24: 207-233.

58. Weinstein, J.N., Steller, M.A., Covell, D.G., Dower, S.K., Segal,
    D.M., Keenan, A.M., Sieber, S.M., and Parker, R.J.: Use of
    monoclonal antibodies for diagnosis and therapy of tumor metastases
    in lymph nodes. [Affinity Chromatography and Biological
    Recognition]{.underline} 1984; 33-42.

59. Blumenthal, R., Kempf, C., Renswoude, J.V., Weinstein, J.N., and
    Klausner, R.D.: Voltage-dependent orientation of membrane proteins.
    In: Oxender, D.L. (Ed) Protein Transport and Secretion. New York:
    Alan R. Liss, 1984; 1-13.

60. Blumenthal, R., Kempf, C., Renswoude, J.V., Weinstein, J.N., and
    Klausner, R.D.: Voltage-dependent orientation of membrane proteins.
    In: Oxender, D.L. (Ed) Protein Transport and Secretion. New York:
    Alan R. Liss, 1984; 1-13.

61. Weinstein, J.N., Ralston, E., Leserman, L.D., Klausner, R.D.,
    Dragsten, P., and Blumenthal, R.: Self-quenching of
    carboxyfluorescein fluorescence: Uses in studying liposome stability
    and liposome-cell interaction. In: Gregoriadis, G. (Ed) Liposome
    Technology, Vol. 3. Boca Raton, FL: CRC Press, 1984; 183-204.

62. Weinstein, J.N., Steller, M.A., Covell, D.G., Holton, O.D., III,
    Keenan, A.M., Sieber, S.M., and Parker, R.J.: Monoclonal anti-tumor
    antibodies in the lymphatics. [Cancer Treat. Reports, Twenty-fifth
    Anniversary Issue]{.underline} 1984; 68: 257-264.

63. Covell, D.G., Steller, M.A., Parker, R.J., and Weinstein, J.N.:
    Delivery of monoclonal antibodies through the lymphatics:
    Characterization by compartmental modeling. [Computer Applications
    in Medical Care]{.underline} 1985; 10: 884-888.

64. Klausner, R.D., Blumenthal, R., Innerarity, T., and Weinstein, J.N.:
    The interaction of apolipoprotein A-I with unilamellar vesicles of
    L--dipalmitoyl phosphatidylcholine. [J. Biol. Chem.]{.underline}
    1985; 260: 13719-13727.

65. Weinstein, J.N., Holton, O.D., Black, C.D.V., Keenan, A.M., Covell,
    D.G., Spaulding, G.F., Barbet, J., Steller, M.A., Sieber, S.M.,
    Talley, M.J., and Parker, R.J.: Monoclonal antitumor antibodies in
    the lymphatics. In: Hickey, R.C., and Sunders, G.F., (Eds) 1985 Year
    Book of Cancer. Chicago, IL: Year Book Medical Publishers, 1985;
    264-266.

66. Weinstein, J.N., Keenan, A.M., Holton, O.D., III, Covell, D.G.,
    Sieber, S.M., Black, C.D.V., Barbet, J., and Parker, R.J.: Use of
    monoclonal antibodies to detect metastases of solid tumors in lymph
    nodes. In: Ceriani, R.L. (Ed) Monoclonal Antibodies and Breast
    Cancer. Martinus Nijhof, Boston, 1985; 218-232.

67. Weinstein, J.N., Parker, R.J., Holton, O.D., III, Keenan, A.M.,
    Covell, D.G., Black, C.D.V., and Sieber, S.M.: Lymphatic delivery of
    monoclonal antibodies: Potential for detection and treatment of
    lymph node metastases. [Cancer Investigation]{.underline} 1985; 3:
    85-95.

68. Covell, D.G., Barbet, J., Holton, O.D., III, Black, C.D.V., and
    Weinstein, J.N.: The pharmacokinetics of monoclonal IgG1, F(ab\')2
    and Fab\' in mice. [Cancer Research]{.underline} 46: 3969-3978,
    1986.

69. Covell, D.G., Barbet, J., Holton, O.D. III, Black, C.V.D., Keenan,
    A.M., Sieber, S.M., and Weinstein, J.N.: Global and local factors in
    the pharmacology of monoclonal antibodies. [American Statistical
    Society Symposium]{.underline}, 1986.

70. Lotze, M.T., Carrasquillo, J.A., Weinstein, J.N., Bryant, G.J.,
    Perentesis, P., Reynolds, J.C., Matis, L.A., Eger, R.R., Keenan,
    A.M., Hellstrom, I., Hellstrom, K.-E., and Larson, S.M.: Monoclonal
    antibody imaging of human melanoma: Radioimmunodetection by
    subcutaneous or systemic injection. [Annals of Surgery]{.underline}
    1986; 204: 223-235.

71. Weinstein, J.N., Black, C.D.V., Barbet, J., Eger, R.R., Parker,
    R.J., Holton, O.D., III, Mulshine, J.L., Keenan, A.M., Larson, S.M.,
    Carrasquillo, J.A., Sieber, S.M., and Covell, D.G.: Selected issues
    in the pharmacology of monoclonal antibodies. In: Tomlinson, E., and
    Davis, S.S. (Eds) Site-specific Drug Delivery: Cell Biology,
    Medicinal and Pharmaceutical Aspects. New York: John Wiley, 1986;
    81-91.

72. Steller, M.A., Parker, R.J., Covell, D.G., Holton, O.D., III,
    Keenan, A.M., Sieber, S.M., and Weinstein, J.N.: Optimization of
    monoclonal antibody delivery via the lymphatics: The
    dose-dependence. [Cancer Research]{.underline} 1986; 46: 1830-1834.

73. Weinstein, J.N., Black, C.D.V., Keenan, A.M., Holton, O.D., III,
    Larson, S.M., Sieber, S.M., Covell, D.G., Carrasquillo, J., Barbet,
    J., and Parker, R.J.: Use of monoclonal antibodies for detection of
    lymph node metastases. In: Reisfeld, R.A., and Sell, S. (Eds)
    Monoclonal Antibodies in Cancer Therapy. New York: Alan R. Liss,
    1986; 473-488.

74. Weinstein, J.N., Blumenthal, R., and Klausner, R.D.:
    Carboxyfluorescein leakage assay for lipoprotein-liposome
    interaction. In: Segrest, J.P., and Albers, J.J. (Eds) Methods in
    Enzymol. Vol. 128, Part A, Academic Press, London, 1986; 657-668.

75. Weinstein, J.N., Holton, O.D., III, Black, C.D.V., Keenan, A.M.,
    Covell, D.G., Spaulding, G.F., Barbet, J., Steller, M.A., Sieber,
    S.M., Talley, M.J., and Parker, R.J.: Regional delivery of
    monoclonal antitumor antibodies: Detection and possible treatment of
    lymph node metastases. [Prog. Clin. Biol. Res.]{.underline} 1986;
    212: 169-181.

76. Weinstein, J.N., and Leserman, L.D.: Liposomes as drug carriers in
    cancer chemotherapy. In: Goldman, I.D. (Ed) The International
    Encyclopedia of Pharmacology and Therapeutics, Vol. 118: Membrane
    Transport of Anti-neoplastic Agents. New York: Pergamon Press, 1986;
    169-194.

77. Eger, R.R., Covell, D.G., Carrasquillo, J., Larson, S.M., Reynolds,
    J., Abrams, P., Morgan, A.C., Schroff, R., Foon, K., and Weinstein,
    J.N.: A kinetic model for the biodistribution of an In-111 labeled
    monoclonal antibody in humans. [Cancer Research]{.underline} 1987;
    47: 3328-3336.

78. Holton, O.D., III, Black, C.D.V., Parker, R.J., Covell, D.G.,
    Barbet, J., Sieber, S.M., Talley, M.J., and Weinstein, J.N.:
    Biodistribution of monoclonal IgG1, F(ab\')2, and Fab\' in mice
    after intravenous injection: A comparison between anti-B cell
    (anti-LyB8.2) and irrelevant (MOPC-21) antibodies. [J.
    Immunol.]{.underline} 1987; 139: 3041-3049.

79. Weinstein, J.N.: Liposomes in the diagnosis and treatment of cancer.
    In: Ostro, M. (Ed) Liposomes. New York: Marcel Dekker, 1987;
    277-338.

80. Keenan, A.M., Weinstein, J.N., Carrasquillo, J.A., Bunn, P.A., Jr.,
    Reynolds, J.C., Foon, K.A., Smarte, N.C., Ghosh, B., Fejka, R.M.,
    Larson, S.M., and Mulshine, J.L.: Immunolymphoscintigraphy and the
    dose-dependence of indium-111-labeled T101 monoclonal antibody in
    patients with cutaneous T-cell lymphoma. [Cancer
    Research]{.underline} 1987; 47: 6093-6099.

81. Keenan, A.M., Weinstein, J.N., Mulshine, J.L., Carrasquillo, J.A.,
    Bunn, P.A., Jr., Reynolds, J.C., Foon, K.A., Perentesis, P., Ghosh,
    B., and Larson, S.M.: Evaluation of lymphoma by
    immunolymphoscintigraphy: Subcutaneous injection of
    indium-111-labeled T101 monoclonal antibody. [J. Nucl.
    Med.]{.underline} 1987; 28: 42-46.

82. Mulshine, J.L., Keenan, A.M., Carrasquillo, J.A., Walsh, T.,
    Linnoila, R.I., Holton, O.D., Harwell, J., Larson, S.M., Bunn, P.A.,
    and Weinstein, J.N.: Immunolymphoscintigraphy of pulmonary and
    mediastinal lymph nodes: A new approach to lung cancer imaging.
    [Cancer Research]{.underline} 1987; 47: 3572-3576.

83. Weinstein, J.N., Black, C.D.V., Holton, O.D., III, Covell, D.G.,
    Parker, R.J., Mulshine, J.L., Lotze, M.T., Carrasquillo, J., Eger,
    R.R., Lewis, A., Larson, S.M., and Keenan, A.M.: Delivery of
    monoclonal antibodies to lymph nodes via the lymphatics. In:
    Winkelhake, J.L., and Holcenberg, J.S. (Eds) The Pharmacology and
    Toxicology of Proteins. New York: Alan R. Liss, 1987; 75-89.

84. Weinstein, J.N., Covell, D.G., Barbet, J., Eger, R.R., Holton, O.D.
    III, Talley, M.J., Parker, R.J., and Black, C.D.V.: The pharmacology
    of monoclonal antibodies. In: Bonavida, B., and Collier, R.J. (Eds)
    Membrane-mediated Cytotoxicity. New York: Alan R. Liss, Inc., 1987;
    279-289.

85. Parker, R.J., Weinstein, J.N., Keenan, A.M., Dower, S.K., Steller,
    M.A., Holton, O.D., and Sieber, S.M.: Targeting of radiolabelled
    monoclonal antibodies in the lymphatics. [Cancer
    Research]{.underline} 1987; 47: 2073- 2076.

86. Quill, H., Carlson, L., Fox, B.S., Weinstein, J.N., and Schwartz,
    R.H.: Optimization of antigen presentation to T cell hybridomas by
    purified Ia molecules in planar membranes: Ia molecule polymorphism
    determines the antigenic fine specificity of the response to
    cytochrome [c]{.underline} peptides. [J. Immunol.
    Methods]{.underline} 1987; 98: 29-41.

87. Weinstein, J.N., Eger, R.R., Covell, D.G., Black, C.D.V., Mulshine,
    J., Carrasquillo, J.A., Larson, S.M., and Keenan, A.M. The
    pharmacology of monoclonal antibodies. [Annals N.Y. Acad.
    Sci.]{.underline} 1987; 507: 199-210.

88. Barbet, J., Black, C.D.V., Holton, O.D., III, and Weinstein, J.N.:
    Specific toxicity to activated T and B lymphocytes of a ricin A
    immunotoxin directed against the class I MHC antigen H-2 K. [J.
    Antibody, Immunoconjugates and Radiopharmaceuticals]{.underline}
    1988; 1: 169-180.

89. Black, C.D.V., Atcher, R.W., Barbet, J., Brechbiel, M.W., Holton,
    O.D. III, Hines, J.J., Gansow, O.A., and Weinstein, J.N.: Selective
    ablation of B lymphocytes in vivo by an alpha emitter, 212bismuth,
    chelated to a monoclonal antibody. [J. Antibody, Immunoconjugates
    and Radiopharmaceuticals]{.underline} 1988; 1: 43-53.

90. Black, C.D.V., Kroczek, R.A., Barbet, J., Weinstein, J.N., and
    Shevach, E.M.: Induction of IL-2 receptor expression in vivo:
    Response to concanavalin A. [Cellular Immunol.]{.underline} 1988;
    111: 420-432.

91. Weinstein, J.N.: Immunolymphoscintigraphy and other regional
    applications of monoclonal antibodies. In: Zalutsky, M.R. (Ed)
    Antibodies in Radiodiagnosis and Therapy. Boca Raton, FL: CRC Press,
    1988; 153-167.

92. Borden, E.C., Bradley, E.C., Evans, C.H., Fox, C.F., Metzgar, R.S.,
    Mitchell, M.S., and Weinstein, J.N.: Biotechnology products in
    cancer therapy. [Cancer Research]{.underline} 1988; 47: 223-225.

93. Weinstein, J.N., and Fujimori, K.: Predictive pharmacology of
    monoclonal antibodies. In: Bannasch, P. (Ed) Cancer Therapy: New
    Trends. Berlin: Springer-Verlag, 1989; 197-199.

94. Fujimori, K., Covell, D.G., Fletcher, J.E., and Weinstein, J.N.: A
    modeling analysis of IgG, F(ab\')2, and Fab in tumors. [Cancer
    Research]{.underline} 1989; 49: 5656-5663.

95. Fujimori, K., and Weinstein, J.N.: Pharmacokinetics and organ
    targeting of monoclonal antibodies. [Advances in
    Immunopharmacology]{.underline} 1989; 4: 127-129.

96. Szebeni, J., Wahl, S.M., Popovic, M., Wahl, L.M., Gartner, S., Fine,
    R.L., Skaleric, U., Friedman, R.M., and Weinstein, J.N.:
    Dipyridamole potentiates the inhibition by azidothymidine and other
    dideoxynucleosides of human immunodeficiency virus replication in
    monocyte/macrophages. [Proc. Natl. Acad. Sci.]{.underline} USA 1989;
    86: 3842-3846.

97. Fujimori, K., Covell, D.G., Fletcher, J.E., and Weinstein, J.N.: A
    modeling analysis of monoclonal antibody percolation through tumors:
    A binding site barrier. [J. Nucl. Med.]{.underline}, 1990; 31:
    1191-1198.

98. Weinstein, J.N.: Antibody lymphoscintigraphy. In: Goldenberg, D.M.
    (Ed) Cancer Imaging with Radiolabeled Antibodies. Kluwer, Boston,
    1990, pp. 365-385.

99. Weinstein, J.N., and Fujimori, K.: Antibody-mediated drug delivery.
    In: J.B. Hooke and G. Poste (Eds) Protein Design and the Development
    of New Therapeutics and Vaccines. New York: Plenum Press, 1990;
    359-370.

100. Viswanadhan, V.N., Weinstein, J.N., and Elwood, P.C.: Secondary
     structure of the human membrane-associated folate binding protein
     using a joint prediction approach. [J. Biol. Structure and
     Dynamics]{.underline} 1990; 7: 985-1001.

101. Szebeni, J., Wahl, L.M., Gartner, S., Popovic, M., Parker, R.,
     Black, C., and Weinstein, J.N.: Inhibition of HIV-1 in
     monocyte/macrophage cultures by
     2\',3\'-dideoxycytidine-5\'-triphosphate, free and in liposomes.
     [AIDS Research and Human Retroviruses]{.underline} 1990; 5:
     691-702.

102. Weinstein, J.N. and Fujimori, K.. The pharmacokinetics of
     monoclonal antibodies and derived peptides. In: Sundwall, A. (Ed.)
     Preclinical Evaluation of Peptides and Recombinant Proteins.
     Stockholm: Skogs Grafiska AB, 1990; 35-41.

103. Betageri, G.V., Szebeni, J., Hung, K., Wahl, L.M., Corcoran, M.,
     and Weinstein, J.N.: Effect of dipyridamole on transport and
     phosphorylation of thymidine and azidothymidine in human
     monocyte/macrophages. [Biochemical Pharmacology]{.underline} 1990;
     40: 867-870.

104. Viswanadhan, V.N., Ghose, A.K., Szebeni, J., and Weinstein, J.N.:
     Mapping the binding site of the nucleoside transporter protein: A
     3D-QSAR study. [Biochim. Biophys. Acta]{.underline} 1990; 1039:
     356-366.

105. Ashorn, P., Moss, B., Weinstein, J.N., Chaudhary, V.K., FitzGerald,
     D.J., Pastan, I., and Berger, E.A.: Elimination of infectious HIV
     from human T-cell cultures by synergistic action of CD4-pseudomonas
     exotoxin and reverse transcriptase inhibitors. [Proc. Natl. Acad.
     Sci.]{.underline} 1990; 87: 8889-8893.

106. Bunow, B. and Weinstein, J.N.: Combo: A new approach to the
     analysis of drug combinations in vitro. [Annals N.Y. Acad.
     Sci.]{.underline} 1990; 616: 490-494.

107. Weinstein, J.N., Schinazi, R.F., Wahl, S.M., Bunow, B., Gartner,
     S., Popovic, M., Wahl, L.M., Weislow, O.S., and Szebeni, J.:
     Synergistic drug combinations in AIDS therapy:
     Dipyridamole-zidovudine in particular and principles of analysis in
     general. [Annals N.Y. Acad. Sci.]{.underline} 1990; 616: 367-384.

108. Szebeni, J., Wahl, S.M., Schinazi, R.F., Popovic, M., Gartner, S.,
     Wahl, L.M., Weislow, O.S., Betageri, G., Fine, R.L., Dahlberg,
     J.E., Hunter, E., and Weinstein, J.N. Dipyridamole potentiates the
     activity of zidovudine and other dideoxynucleosides against HIV-1
     in cultured cells. [Annals N.Y. Acad. Sci.]{.underline} 1990; 616:
     613-616.

109. Patel, S.S., Szebeni, J., Wahl, L.M., and Weinstein, J.N. Effect of
     dipyridamole on transport and phosphorylation of dideoxycytidine
     and cytidine in human monocyte-macrophages. [Antimicrobial Agents
     and Chemother.]{.underline} 1991; 35: 1250-1253.

110. Szebeni, J., Patel, S.S., Hung, K., Wahl, L.M., and Weinstein, J.N.
     The effect of thymidine and uridine on the phosphorylation of
     3\'-azido-3\'-deoxythymidine (Zidovudine) in human mononuclear
     cells. [Antimicr. Agents. Chemother.]{.underline} 1991; 198-200.

111. Szebeni, J. and Weinstein, J.N.: Dipyridamole binding to proteins
     in human plasma and in tissue culture media. [J. Lab. Clin.
     Med.]{.underline} 1991[;]{.underline} 117: 485-492.

112. Mulshine, J.L., Carrasquillo, J.A., Weinstein, J.N., Keenan, A.M.,
     Reynolds, J.C., Herdt, J., Bunn, P.A., Sausville, E., Eddy, J.,
     Cotelingam, J.D., Perentesis, P., Pinsky, C., and Larson, S.M.:
     Direct intralymphatic injection of radiolabeled 111-In-T101 in
     patients with cutaneous T-cell lymphoma. [Cancer
     research]{.underline} 1991; 51:.688-695.

113. Fujimori, K., Fisher, D.R., and Weinstein, J.N.: Integrated
     microscopic-macroscopic pharmacology of monoclonal antibody
     radioconjugates: The radiation dose distribution. [Cancer
     Research]{.underline} 1991; 51: 4821-4827.

114. van Osdol, W., Fujimori, K., and Weinstein, J.N. An analysis of
     monoclonal antibody distribution in microscopic tumor nodules:
     Consequences of a \"binding site barrier.\" [Cancer
     Research]{.underline} 1991; 51: 4776-4784.

115. Viswanadhan, V.N., Denckla, B., and Weinstein, J.N. A joint
     prediction algorithm (Q7-JASEP) improves the prediction of protein
     secondary structure: Application to / proteins.
     [Biochemistry]{.underline}, 1991; 30: 11164-11172.

116. Szebeni, J., Dieffenbach, C., Wahl, S.M., Venkateshan, C.N., Yeh,
     A., Popovic, M., Gartner, S., Wahl, L.M., Peterfy, M., Friedman,
     R.M., and Weinstein, J.N. Induction of interferon- by human
     immunodeficiency virus type-1 in human monocyte-macrophage
     cultures. [Journal of Virology,]{.underline} 1991; 65: 6362-6364.

117. Reddy, M.R., Viswanadhan, V.N., and Weinstein, J.N.: Relative
     differences in the binding free energies of HIV1 protease
     inhibitors: A thermodynamic cycle perturbation approach. [Proc.
     Natl. Acad. Sci. U.S.A.]{.underline}, 1991; 88: 10287-10291.

118. Weinstein, J.N., and Bunow, B. COMBO: New concepts and methods for
     designing and analyzing experiments on combination therapy. In:
     A L. Goldstein and E. Garaci (Eds), Combination Therapies:
     Biological Response Modifiers in the Treatment of Cancer and
     Infectious Diseases. Plenum Press, N.Y., 1992, pp. 29-38.

119. Hui, T.E., Fisher, D.R., Press, O.W., Eary, J.F., Weinstein, J.N.,
     Badger, C.C., and Bernstein, I.D. Localized beta dosimetry of
     131I-labeled antibodies in follicular lymphoma. [Medical
     Physics]{.underline}, 1992; 19: 97-104.

120. Weinstein, J.N, and van Osdol, W. Early intervention in cancer
     using monoclonal antibodies and other biological ligands:
     Micropharmacology and the \"binding site barrier.\". [Cancer
     Research]{.underline}, 1992; 52: 2747s-2751s.

121. Weinstein, J.N., and van Osdol, W. The macroscopic and microscopic
     pharmacology of monoclonal antibodies. [Intl J.
     Immunopharm.]{.underline}, 1992; 14: 457-463.

122. Weinstein, J.N. and van Osdol, W.: Immunolymphoscintigraphy in the
     diagnosis of lymphoma and solid tumors. [Progress in
     Lymphology]{.underline} 1992; 13: 295-302.

123. Kageyama, S., Weinstein, J.N., Shirasaka, T., Kempf, D.J., Norbeck,
     D.W., Plattner, J.J., Erickson, J., and Mitsuya, H.: In vitro
     inhibition of HIV-1 replication by c2 symmetry-based HIV protease
     inhibitors as single agents or in combination. [Antimicr. Agents.
     Chemother.]{.underline}, 1992; 36: 926-933.

124. Juweid, M., Neumann, R., Paik, C., Perez-Bacete, M.J., Sato, J.,
     van Osdol, W., Weinstein, J.N.: Microdistribution of monoclonal
     antibodies in solid tumors: Effect of the binding site barrier,
     [Cancer Research]{.underline}, 1992; 52: 5144-5153.

125. Weinstein, J.N., Kohn, K.W., Grever, M.R., Viswanadhan, V.N.,
     Rubinstein, L.V., Monks, A., Scudiero, D.A., Welch, L., Koutsoukos,
     A., Chiausa, A.J., and Paull, K.D. Neural computing in cancer drug
     development: Predicting mechanism of action. [Science]{.underline},
     1992; 258: 447-451.

126. Weinstein, J.N., Rubinstein, L.V., Koutsoukos, A.D., Kohn, K.W.,
     Grever, M.R., Monks, A., Scudiero, D.A., Welch, L., Chiausa, A.J.,
     Fojo, A.T., Viswanadhan, V.N., and Paull, K.D. Neural networks in
     the discovery of new treatments for cancer and AIDS. [Symp. World
     Congress on Neural Networks]{.underline}, 1993; 1: 111-116.

127. Betageri, G.V., Black, C.D.V., Szebeni, J., Wahl, L.M., and
     Weinstein, J.N. Fc-receptor mediated targeting of antibody-bearing
     liposomes to human monocyte/macrophages. [J. Pharmacy and
     Pharmacology]{.underline}, 1993; 45: 48-53.

128. Juweid, M., Sato, J., Paik, C., Onay-Basaran, S.O., Weinstein,
     J.N., and Neumann, R.: A simple method for affinity purification of
     labeled monoclonal antibodies. [Nuclear Medicine
     Biology]{.underline}, 1993; 20: 311-316.

129. van Osdol, W.W., Sung, C., Dedrick, R.L., and Weinstein, J.N. A
     distributed pharmacokinetic model of two-step imaging and treatment
     protocols: Application to streptavidin-conjugated monoclonal
     antibodies and radiolabeled biotin. [J. Nucl. Med.]{.underline},
     1993; 34: 1552-1564.

130. Chabner, B.A., Weinstein, J.N., Paull, K.D., and Grever, M.R. Cell
     line-based screening for new anticancer drugs. In: Banzet, P.,
     Holland, J.F., Khayat, D., and Weil, M. (Eds.) [Cancer Treatment,
     an Update]{.underline}. Paris: Springer-Verlag France, 1994; 10-16.

131. Weinstein, J.N., Neural networks and predictive statistics in drug
     discovery. [Handbook for the International Forum on Advances in
     Screening Technology and Data Management]{.underline}, 1994; 79-83.

132. Weinstein, J.N., Casciari, J.J., Raghavan, K., Buolamwini, J., and
     Myers, T.G. Neural networks in the biomedical sciences: A survey of
     386 publications since the beginning of 1991. [Symp. World Congress
     on Neural Networks]{.underline}, 1994; 1: 121-126.

133. Weinstein, J.N., Myers, T., Buolamwini, J., Raghavan, K.,
     Viswanadhan, V.N., Licht, J., Rubinstein, L.V., Koutsoukos, A.D.,
     Kohn, Zaharevitz, D., K.W., Grever, M.R., Monks, A., Scudiero,
     D.A., Chabner, B.A., Anderson, N.L., Paull, K.D. Predictive
     statistics and artificial intelligence in the U.S. National Cancer
     Institute\'s drug discovery program for cancer and AIDS. [Stem
     Cells]{.underline}, 1994; 12: 13-22.

134. Hendrix, C.W., Flexner, C. Szebeni, J., Kuwahara, S., Pennypacker,
     S., Weinstein, J.N., and Lietman, P.S.: Dipyridamole\'s effect on
     zidovudine pharmacokinetics and tolerance in asymptomatic
     HIV-infected subjects. [Antimicrob. Agents and
     Chemother.]{.underline}, 1994; 38: 1036-1040.

135. Koutsoukos, A.D., Rubinstein, L.V., Faraggi, D., Kalyandrug, S.,
     Weinstein, J.N., Paull, K.D., Kohn, K.W., and Simon, R.M.
     Discrimination techniques applied to the NCI in vitro antitumor
     drug screen: Predicting biochemical mechanism of action.
     [Statistics in Medicine]{.underline}, 1994; 13: 719-730.

136. Saga, T., Weinstein, J.N., Jeong, J.M., Heya, T., Lee, J.T., Le,
     Nhat, Paik, C.H., Sung, C., and Neumann, R.D. Two-step targeting of
     experimental lung metastases with biotinylated antibody and
     radiolabeled streptavidin. [Cancer Research]{.underline}, 1994; 54:
     2160-2165.

137. Sung, C., van Osdol, W.W., Saga, T., Neumann, R.D., Dedrick, R.L.,
     and Weinstein, J.N. Steptavidin distribution in metastatic tumors
     pretargeted with a biotinylated monoclonal antibody: Theoretical
     and experimental pharmacokinetics, [Cancer Research]{.underline},
     1994; 54: 2166-2175.

138. Weinstein, J.N., Myers, T.G., Fan, Y., Paull, K.D., Zaharevitz,
     D.W., Kohn, K.W., and van Osdol, W.W. An \"information-intensive\"
     strategy for drug discovery at the National Cancer institute: The
     role of neural networks. [Symp. World Congress on Neural
     Networks]{.underline}, 1995; II: 750-753.

139. van Osdol, W.W., Myers, T.G., Paull, K.D., Kohn, K.W., and
     Weinstein, J.N. [Symp. World Congress on Neural
     Networks]{.underline}, 1995; II: 762-766.

140. Raghavan, K., Buolamwini, J.K., Fesen, M.R., Pommier, Y., Kohn,
     K.W., and Weinstein, J.N. Three-dimensional QSAR of HIV integrase
     inhibitors: A comparative molecular field analysis (CoMFA) study.
     [J. Med. Chem.]{.underline}, 1995; 38: 890-897.

141. Casciari, J.J., Hollingshead, M., Alley, M., Mayo, J., Malspeis,
     L., Miyauchi, S., Grever, M.R., and Weinstein, J.N. Growth and
     chemotherapeutic response of human tumor cells grown as solid in
     vitro tumors inside hollow fibers. [J. Natl. Cancer
     Inst.]{.underline}, 1994; 86: 1846-1852.

142. Chung, K.N., Paik, T.H., Roberts, S., Kim, C.H., Kirassova, M.,
     Weinstein, J.N., Trepel, J.B., and Elwood, P.C. Site-directed
     mutagenesis of tryptophan residues to conserved hydrophobic
     residues inhibits the processing of human KB cell folate receptor.
     [Arch. Biochem. and Biophys.]{.underline} 1994; 315: 407-414.

143. van Osdol, W.W., Myers, T.G., Paull, K.D., Kohn, K.W., and
     Weinstein, J.N. Use of the Kohonen self-organizing map to study the
     mechanisms of action of chemotherapeutic agents. [J. Natl. Cancer
     Inst.]{.underline}, 1994; 86: 1853-1859.

144. Lori, F., Malykh, A., Cara, A., Sun, D., Weinstein, J.N.,
     Lisziewicz, J., and Gallo, R.C. Hydroxyurea as a novel and potent
     inhibitor of human immunodeficiency virus type 1 replication.
     [Science]{.underline}, 1994; 266: 801-805.

145. Weinstein, J.N. and Myers, T.G. Information resources for liposome
     research: The drug discovery program of the U.S. National Cancer
     Institute. [J. Liposome Research]{.underline}, 1995; 5: 837-844.

146. Mazumder, A., Raghavan, K., Weinstein, J.N., Kohn, K.W., and
     Pommier, Y. Inhibition of human immunodeficiency virus type-1
     integrase by curcumin. [Biochem. Pharmacol.]{.underline}, 1995;
     49:1165-1170.

147. Chokekjichai, S., Shirasaka, T., Weinstein, J.N., and Mitsuya, H.
     In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in
     resting and activated cells: Implications for its combined use with
     AZT or ddI. [Antiviral Research]{.underline}, 1995; 28: 25-38.

148. Alvarez, M., Paull, K., Hose, C., Lee, J.-S., Weinstein, J.N.,
     Grever, M., Bates, S., Fojo, T. Generation of a drug resistance
     profile by quantitation of mdr-1/P-glycoprotein expression in the
     cell lines of the NCI anticancer drug screen. [J. Clinical
     Investig.]{.underline}, 1995; 95: 2205-2214.

149. Saga, T., Neumann, R.D., Heya, T., Sato, J., Kinuya, S., Le, N.,
     Paik, C.H., and Weinstein, J.N.: Targeting cancer micrometastases
     with monoclonal antibodies: A \"binding site barrier.\" [Proc. Natl
     Acad. Sci. U.S.A.]{.underline}, 1995; 92: 8999-9003.

150. Bates, S.E., Fojo, A.T., Weinstein, J.N., Paull, K.D., Myers, T.G.,
     and Chabner, B.A. Molecular targets in the National Cancer
     Institute Drug Screen. [J Cancer Res Clin Oncol.]{.underline},
     1995; 121: 495-500.

151. Viswanadhan, V.N., Mueller, G.A., Basak, S.C., and Weinstein, J.N.
     A new QSAR algorithm combining principal component analysis with a
     neural network: Application to calcium channel antagonists.
     [NetSci]{.underline} (electronic publication), January, 1996
     (<http://www.netsci.org/Science/Compchem/feature07.html>).

152. Viswanadhan, V.N., Reddy, M.R., Wlodawer, A., Varney, M.D., and
     Weinstein, J.N. An approach to rapid estimation of relative binding
     affinities of enzyme inhibitors: Application to peptidomimetic
     inhibitors for the HIV-1 protease. [J. Med. Chem.]{.underline}
     1996; 39: 705-712.

153. Casciari, J., Sato, H., Durum, S.K., Fiege, J., Weinstein, J.N.
     Reference databases of cytokine structure and function. In: Pinedo,
     H.M., Longo, D.L., and Chabner, B.A. (Eds.) [Chemotherapy and
     Biological Response Modifiers Annual 16.]{.underline} Amsterdam:
     Elsevier, 1996; 315-346.

154. Weinstein, J.N., Waltham, M.C., and Myers, T.G. Neural networks in
     drug discovery. [Symp. World Congress on Neural
     Networks]{.underline}, 1996; 1.

155. Casciari, J., Sato, H., Durum, S.K., Fiege, J., and Weinstein, J.N.
     Tabular lexicon of cytokine structure and function. In: Chabner,
     B.A. and Longo, D. (Eds.) [Cancer Chemotherapy and Biotherapy:
     Principles and Practice]{.underline}. Philadelphia:
     Lippincott-Raven, 1996; 787-810.

156. Dearing, M.P., Englee-Miller, M.J., Kratzke, R.A., Kramer, B.S.,
     Chu, E., Weinstein, J.N., Anderson, M., Venzon, D., Mulshine, J.L.,
     and Gazdar, A.F. Dipyridamole mediated enhanced antiproliferative
     activity of 10-ethyl-10-deazaaminopterin (10-EDAM) against human
     lung cancer cell lines, [J. Cell. Biochem]{.underline} 1996;
     24:165-172.

157. Buolamwini, J., Raghavan, K., Fesen, M.R., Pommier, Y., Kohn, K.W.,
     and Weinstein, J.N. Electrotopological state analysis of flavones
     as HIV-1 integrase inhibitors. [Pharm. Research]{.underline} 1996;
     13: 1891-1894, 1996.

158. Shi, L.M., Fan, Y., Myers, T.G., and Weinstein, J.N. Genetic
     function approximation in the molecular pharmacology of cancer.
     [Symp. Intl. Congress on Neural Networks,]{.underline} 1997; 1-.

159. Li, G., Waltham, M., Unsworth, E., Treston, A., Anderson, N.L., and
     Weinstein, J.N. Rapid protein identification from two-dimensional
     polyacrylamide gels by MALDI mass spectrometry.
     [Electrophoresis]{.underline} 1997; 18:391-402.

160. Myers, T.G., Waltham, M., Li, G., Buolamwini, J.K., Scudiero, D.A.,
     Rubinstein, L.V., Paull, K.D., Sausville, E.A., and Anderson, N.L.,
     and Weinstein, J.N. A protein expression database for the molecular
     pharmacology of cancer. [Electrophoresis]{.underline} 1997;
     18:647-653.

161. O\'Connor, P.M., Jackman, J., Bae, I., Myers, T.G., Fan, S.,
     Scudiero, D.A., Monks, A., Sausville, E.A., Weinstein, J.N.,
     Friend, S., Fornace, A.J., Jr., and Kohn, K.W. Characterization of
     the p53 tumor suppressor pathway in the NCI anticancer drug screen
     cell lines and relationships with chemosensitivity, [Cancer
     Research,]{.underline} 1997; 57: 4285-4300.

162. Burke, H.B., Goodman, P.H., Rosen, D.B., Weinstein, J.N., Hellier,
     J.H., Winchester, D.P., Harrell, F.E., Marks, J.R., Bostwick, D.G.,
     Osteen, R.T., Zincke, H., and Henson, D.E. Improving cancer
     survival prediction accuracy. [Cancer]{.underline} 1997; 79:
     857-862.

163. Wosikowski, K., Schuurhuis, D., Johnson, K., Paull, K.D., Myers,
     T.G., Weinstein, J., and Bates, S.E. Use of EGF receptor, c-erbB2
     and TGF gene expression profiles in the National Cancer Institute
     anticancer drug screen to identify EGF receptor and c-erbB2 pathway
     inhibitors. [J. Natl. Cancer Inst.]{.underline}, 1997; 89:
     1505-1515.

164. Weinstein, J.N., Myers, T.G., O\'Connor, P.M., Friend, S.H.,
     Fornace, A.J., Kohn, K.W., Fojo, T., Bates, S.E., Rubinstein, L.V.,
     Anderson, N.L., Buolamwini, J.K., van Osdol, W.W., Monks, A.P.,
     Scudiero, D.A., Sausville, E.A., Zaharevitz, D.W., Bunow, B.,
     Viswanadhan, V.N., Johnson, G.S., Wittes, R.E., and Paull, K.D. An
     information-intensive approach to the molecular pharmacology of
     cancer. [Science]{.underline} 1997; 275:343-349.

165. Shi, L.M., Fan, Y., Myers, T.G., Waltham, M., Paull, K.D., and
     Weinstein, J.N. Mining the anticancer activity database generated
     by the U.S. National Cancer Institute\'s drug discovery program
     using statistical and artificial intelligence techniques,
     [Mathematical Modeling and Scientific Computing]{.underline} 1998;
     38:189-199.

166. Shi, L.M., Myers, T.G., Fan, Y., O\'Connor, P.M., Paull, K.D.,
     Friend, S.H., and Weinstein, J.N. Mining the National Cancer
     Institute anticancer drug discovery database: Cluster analysis of
     ellipticine analogs with p53-inverse and central nervous
     system-selective patterns of activity. [Molecular
     Pharmacology]{.underline} 1998; 53: 241-251.

167. Shi, L.M., Fan, Y., Myers, T.G., Paull, K.D., and Weinstein, J.N.
     Mining the NCI anticancer drug discovery databases: Genetic
     function approximation for the quantitative structure-activity
     relationship study of anticancer ellipticine analogs. [J. Chem.
     Inf. Comput. Sci.]{.underline} 1998; 38: 189-199.

168. Fan, Y., Weinstein, J.N., Kohn, K.W., Shi, L.M., and Pommier, Y.
     Molecular modeling studies of the DNA - topoisomerase I ternary
     cleavable complex with camptothecin. [J. Med. Chem.]{.underline}
     1998; 41: 2216-2226.

169. Weinstein, J.N., Fishing expeditions, [Science]{.underline} 1998;
     282: 628-629 (letter in Genome issue).

170. Carrier, F., Georgel, P.T., Pourquier, P., Blake, M., Kontny, H.U.,
     Antinore, M.J., Gariboldi, M., Myers, T.G., Weinstein, J.N.,
     Pommier, Y., and Fornace, A.J., Jr. Gadd45, a p53-responsive stress
     protein, modifies DNA on damaged chromatin. [Molec. Cell
     Biol.]{.underline} 1999; 19: 1673-1685.

171. Fornace, A.J., Jr., Amundson, S.A., Bittner, M., Myers, T.G.,
     Meltzer, P., Weinstein, J.N., and Trent, J. The complexity of
     radiation stress responses: Analysis by informatics and functional
     genomics approaches. [Gene Expression]{.underline} 1999; 7:
     387-400.

172. Tanabe, L., Smith, L.H., Lee, J.K., Scherf, U., Hunter, L., and
     Weinstein, J.N. MedMiner: An internet tool for filtering and
     organizing biomedical information, with application to gene
     expression profiling. [BioTechniques]{.underline}. 1999; 27:
     1210-1217.

173. Weinstein, J.N., Waltham, M., Reinhold, W., Lee, J.K., Smith, L.H.,
     Andrews, D., Tanabe, L., Zhou, Y., Myers, T.G., Buolamwini, J.K.,
     and Scherf, U. The current revolution in cancer drug discovery:
     Genomics, proteomics, and bioinformatics. In [Fighting against
     Cancer: Progress and New Hopes]{.underline}, pg 21-36; 2000 \[ISSN
     1344-2368\].

174. van Osdol, W.W., Myers, T.G., and Weinstein, J.N. Neural network
     techniques for the informatics of cancer drug discovery. [Methods
     Enzymol.]{.underline} 2000; 321: 369-395.

175. Rindflesch, T.C., Tanabe, L., Weinstein, J.N., and Hunter, L.
     EDGAR: Extraction of drugs, genes and relations from the biomedical
     literature. [Pac. Symp. Biocomput.]{.underline} 2000; 571-528.
     (refereed)

176. Shi, L.M., Lee, J.K., Fan, Y., Waltham, M., Andrews, D.T., Scherf,
     U., Paull, K.D., and Weinstein, J.N. Mining and visualizing large
     anticancer drug discovery databases. [J. Chem. Information and
     Comput. Sci.]{.underline} 2000; 40: 367-379.

177. Lisziewicz, J., Zeng, G., Weinstein, J.N., and Lori, F. Combination
     gene therapy: Synergistic inhibition of HIV-1 Tat and Rev function
     by one RNA molecule, [Hum. Gene Ther.]{.underline} 2000; 11:
     807-815.

178. Weinstein, J.N. and Buolamwini, J.K. Molecular targets in cancer
     drug discovery: Cell-based profiling. [Current Pharmaceutical
     Design]{.underline} 2000; 6: 473-483.

179. Ross, D.T., Scherf, U., Eisen, M.B., Perou, C.M., Spellman, P.,
     Iyer, V., Jeffrey, S.S., Van de Rijn, M., Waltham, M.,
     Pergamenschikov, A., Lee, J.C.F., Lashkari, D., Shalon, D., Myers,
     T.G., Weinstein, J.N., Botstein, D., and Brown, P.O. Systematic
     variation in gene expression patterns in human cancer cell lines.
     [Nature Genetics]{.underline} 2000; 24: 227-235.

180. Scherf, U., Ross, D.T., Waltham, M., Smith, L.H., Lee, J.K., Kohn,
     K.W., Reinhold, W.C., Myers, T.G., Andrews, D.T., Scudiero, D.A.,
     Eisen, M.B., Sausville, E.A., Pommier, Y., Botstein, D., Brown,
     P.O., and Weinstein, J.N. A cDNA microarray gene expression
     database for the molecular pharmacology of cancer. [Nature
     Genetics]{.underline} 2000; 24: 236-244.

181. Weinstein, J.N. Pharmacogenomics: Teaching old drugs new tricks.
     [New England J. Med.]{.underline} 2000; 343: 1408-1409.

182. Hastie, T., Tibshirani, R., Eisen, M., Brown, P., Ross, D., Scherf,
     U., Weinstein, J.N., Alizadeh, A., Staudt, L., and Botstein, D.
     Gene shaving: A new class of clustering methods for expression
     arrays. Technical Report, Statistics Department, Stanford
     University, 2000

183. Fan, Y., Shi, L.M., Myers, T., Kohn, K.W., Pommier, Y., and
     Weinstein, J.N. Quantitative structure-antitumor activity
     relationships of camptothecin analogs: Cluster analysis and genetic
     algorithm-based studies. [J. Med. Chem]{.underline}. 2001;
     44:3254-3263.

184. Viswanadhan, V.N., Mueller, G.A., Basak, S.C., and Weinstein, J.N.
     Comparison of a neural net-based QSAR algorithm (PCANN) with
     hologram- and multiple linear regression-based QSAR approaches:
     Application to 1,4-dihydropyridine-based calcium channel
     antagonists. [J. Chem. Inf. Comput. Sci]{.underline}. 2001;
     41:505-511.

185. Viswanadhan, V.N., Ghose, A.K., Kiselyov, A., Weinstein, J.N., and
     Wendeloski, J.J. Knowledge-based approaches for the design of small
     molecule libraries for drug discovery. In: Ghose, A.K. and
     Viswanadhan, V.N. (Eds) [Combinatorial library design and
     evaluation for drug discovery: Principles, methods, software tools
     and applications]{.underline}. Marcel-Dekker, New York

186. Buckner, J.C., Moynihan, T.J., Quinn, D.I., Schlegel, U.,
     Ali-Osman, F., Srivenugopal, K., Sawaya, R., Esteller, M., Herman,
     J.G., and Weinstein, J.N. The DNA-Repair Gene MGMT and the Clinical
     Response of Gliomas to Alkylating Agents. [New England J.
     Med.]{.underline} 2001; 344:686-688 (commentary).

187. Weinstein, J.N. Searching for pharmacogenomic markers: The synergy
     between omic and hypothesis-driven research. [Disease
     Markers]{.underline} 2001; 17:77-88.

188. Staunton, J.E., Slonim, D.K., Coller, H.A., Tamayo, P., Angelo,
     M.J., Park, J., Scherf, U., Lee, J.K., Weinstein, J.N., Mesirov,
     J.P., Lander, E.S., and Golub, T.R. Chemosensitivity prediction by
     transcriptional profiling. [Proc. Natl. Acad. Sci.
     U.S.A.]{.underline} 2001; 98:10787-10792.

189. Weinstein, J.N., Scherf, U., Lee, J.K., Nishizuka, S., Gwadry, F.,
     Ajay, Bussey, K., Kim, S., Smith, L.H., Tanabe, L., Richman, S.,
     Alexander, J., Kouros-Mehr, H., Maunakea, A., and Reinhold, W.C.
     The bioinformatics of Microarray gene expression profiling.
     [Cytometry]{.underline} 2002; 47:46-49.

190. Weinstein, J.N. Searching for pharmacogenomic markers: The synergy
     between omic and hypothesis-driven research. [Disease
     Markers]{.underline} 2001; 17:77-88.

191. Zhou, Y., Gwadry, F.G., Reinhold, W.C., Miller, L., Smith, L.H.,
     Scherf, U., Liu, E., Kohn, K.W., Pommier, Y., and Weinstein, J.N.
     Transcriptional regulation of mitotic genes by camptothecin-induced
     DNA damage: Microarray analysis of dose- and time-dependent
     effects. [Cancer Res.]{.underline} 2002; 62:1688-1695.

192. Weinstein, J.N. 'Omic' and hypothesis-driven research in the
     molecular pharmacology of cancer. [Current Opinion in
     Pharmacology]{.underline} 2002; 2:361-365.

193. Blower, P., Jr., Yang, C., Fligner, M.A., Verducci, J.S., Yu, L.,
     Richman, S., and Weinstein, J.N. Pharmacogenomic Analysis:
     Correlating molecular substructure classes with microarray gene
     expression data. [The Pharmacogenomics Journal
     (Nature)]{.underline} 2002; 2:259-271.

194. Feng, W., Wang, G., Zeeberg, B.R., Guo, K., Fojo, A.T., Kane, D.W.,
     Reinhold, W.C., Lababidi, S., Weinstein, J.N., Wang, M.D.
     Development of gene ontology tool for biological interpretation of
     genomic and proteomic data. [Proc. AMIA Symp.]{.underline} 2003;
     839.

195. Daoud, S.S., Munson, P.J., Reinhold, W.C., Young, L., Prabhu, V.V.,
     Yu, Q., LaRose, J., Kohn, K.W., Weinstein, J.N., and Pommier, Y.
     Impact of p53-knockout and topotecan treatment on gene expression
     profiles in human colon carcinoma cells: A pharmacogenomics study.
     [Cancer Res.]{.underline} 2003; 63:2782-2793.

196. Bussey, K.J., Kane, D., Sunshine, M., Narasimhan, S., Nishizuka,
     S., Reinhold, W.C., Zeeberg, B., Ajay, Weinstein, J.N. MatchMiner:
     A tool for batch navigation among gene and gene product
     identifiers. [Genome Biol.]{.underline} 2003; 4:R27.

197. Reinhold, W.C., Kouros-Mehr, H., Kohn, K.W., Maunakea, A.K.,
     Lababidi, S., Roschke, A., Stover, K., Alexander, J., Pantazis, P.,
     Miller, L., Liu, E., Kirsch, I.R., Urasaki, Y., Pommier, Y., and
     Weinstein, J.N. Apoptotic susceptibility of cancer cells selected
     for camptothecin resistance: Gene expression profiling, functional
     analysis, and molecular interaction mapping. [Cancer
     Res]{.underline}. 2003; 63:1000-1011.

198. Lee, J.K., Bussey, K.J., Gwadry, F.G., Reinhold, W., Riddick, G.,
     Pelletier, S.L., Nishizuka, S., and Weinstein, J.N. Comparing cDNA
     and oligonucleotide array data: Concordance of gene expression
     across platforms for the NCI-60 cancer cells. [Genome
     Biology]{.underline} 2003; 4: R82.

199. Weinstein, J.N., Nishizuka, S., Reinhold, W.C., Bussey, K., Kim,
     S., Major, S., Lababidi, S., Feng, W., Wang, G., Raffeld, M.,
     Sunshine, M., Narasimhan, S., Zeeberg, B., Wang, M., Lee, J.K., and
     Kane, D. Cancer drug discovery: Genomics, Proteomics, and
     Bioinformatics. [Molecular Target Therapy of Cancer]{.underline},
     Vol. 1, 2004.

200. Zeeberg, B.R., Feng, W., Wang, G., Wang, M.D., Fojo, A.T., Kane,
     D.W., Reinhold, W.C., Lababidi, S., Bussey, K., Riss, J., Barrett,
     J.C., and Weinstein, J.N. GoMiner: A resource for biological
     interpretation of genomic and proteomic data. [Genome
     Biology]{.underline} 2003; 4:R28.

201. Nishizuka, S., Chen, S.-T., Gwadry, F.G., Alexander, J., Scherf,
     U., Reinhold, W.C., Waltham, M., Charboneau, L., Young, L., Bussey,
     K.J., Kim, S., Lababidi, S., Lee, J.K., Pittaluga, S., Munson,
     P.J., Petricoin, E.F., III, Liotta, L.A., Hewitt, S.M., Raffeld,
     M., and Weinstein, J.N. Diagnostic markers that distinguish colon
     and ovarian adenocarcinomas: Identification by genomic, proteomic,
     and tissue array profiling. [Cancer Res.]{.underline}
     2003;65:5243-5250.

202. Yoshida, A., Urasaki, Y., Waltham, M., Bergman, A-C., Pourquier,
     P., Rothwell, D.G., Inuzuka, M., Weinstein, J.N., Ueda, T.,
     Appella, E., Hickson, I.D., and Pommier, Y. Human
     apurinic/apyrimidinic endonuclease (Ape 1) and its N-terminal
     truncated form (AN34) are involved in DNA fragmentation during
     apoptosis. [J. Biol. Chem.]{.underline} 2003; 278: 37768-37776.

203. Nishizuka, S., Charboneau, L., Young, L., Major, S., Reinhold,
     W.C., Waltham, M., Kouros-Mehr, H., Bussey, Lee, J.K., Munson,
     P.J., Petricoin, E., III, Liotta, L.A., Weinstein, J.N. Proteomic
     profiling of the NCI60 cancer cell lines using new high density
     'reverse-phase' lysate microarrays. [Proc. Natl. Acad.
     Sci]{.underline}. 2003; 100: 14229-14234.

204. Weinstein, J.N. and Pommier, Y. Transcriptomic analysis of the
     NCI-60 cancer cell lines. [Comptes Rendus Biology]{.underline}
     2003; 326:909-920.

205. Kim, S., Weinstein, J.N., and Grefenstette, J.J. Inference of
     large-scale topology of gene regulation networks by neural nets.
     Proc. IEEE International Conference of Systems, Man, and
     Cybernetics, 2003; 3969-3975.

206. Roschke, A.V., Tonon, G., Gehlhaus, K.S., McTyre, N., Bussey, K.J.,
     Lababidi, S., Scudiero, D.A., Weinstein, J.N., Kirsch, I.R.
     Karyotypic complexity of the "NCI-60" drug-screening panel. [Cancer
     Res.]{.underline}, 2003; 63: 8634-8647.

207. Weinstein, J.N. Linking drugs and genes: Pharmacogenomics,
     pharmacoproteomics, bioinformatics, and the NCI-60. In: Brenner, C.
     and Duggan, D. (Eds.), [Oncogenomics: Molecular Approaches to
     Cancer.]{.underline} , Hoboken, N.J.,: John Wiley & Sons. 2004;
     117-137.

208. Weinstein, J.N. Integromic analysis of the NCI-60 cancer cell
     lines. [Breast Disease]{.underline} 2004; 19: 11-22.

209. Zeeberg, B.R.,\* Riss, J.\*, Kane, D.W., Bussey, K.J., Uchio, E.,
     Linehan, W.M.,Barrett, J.C., Weinstein, J.N. Mistaken identifiers:
     Gene name errors can be introduced inadvertently when using Excel
     in bioinformatics. [Biomed. Central Bioinformatics]{.underline}
     2004; 5: 80. \*joint first authors.

210. Kohn, K.W., Riss, J., Aprelikova, O., Weinstein, J.N., Pommier, Y.,
     Barrett, J.C. Properties of switch-like bioregulatory networks
     studied by simulation of the hypoxia response control system.
     [Molec. Biol. of the Cell,]{.underline} 2004; Mol Biol Cell. 2004;
     15: 3042-3052.

211. Huang, Y., Anderle, P., Bussey, K.J., Barbacioru, C., Shankavaram,
     U., Dai, Z., Reinhold, W.C., Papp,A., Weinstein, J.N., and
     Sadee, W. Membrane transporters and channels: role of the
     transportome in cancer chemosensitivity and chemoresistance.
     [Cancer Res.]{.underline} 2004; 64: 4294-4301.

212. Szakacs, G., Annereau, J.-P., Lababidi, S., Shankavaram, U.,
     Arciello, A., Bussey, K.J., Reinhold, W.C., Guo, Y., Kruh, G.D.,
     Reimers, M., Weinstein, J.N., Gottesman, M.M. Predicting drug
     sensitivity and resistance: Profiling ABC transporter genes in
     cancer cells. [Cancer Cell]{.underline} 2004; 6: 129-137.

213. Mulshine, J.L. and Weinstein, J.N. Is the gene expression pattern
     of lung cancer detected by screening with spiral computed
     tomography different from that of symptom-detected lung cancer?
     [Clinical Cancer Research]{.underline} 2004; 10: 5973-5974.

214. Annereau, J.-P., Szakacs, G., Tucker, J., Arciello, A., Cardarelli,
     C., Collins, J., Grissom, S., Zeeberg, B., Reinhold, W.C.,
     Weinstein, J.N., Pommier, Y., Paules, R., and Gottesman, M.M.
     Analysis of ABC transporter-expression in drug-selected cell lines
     by a microarray dedicated to multidrug resistance. [Molec.
     Pharmacol.]{.underline} 2004; 66(6): 1397-1405.

215. Aladjem, M.I., Pasa, S., Parodi, S., Weinstein, J.N., Pommier, Y.,
     Kohn, K.W. Molecular Interaction Maps\--A Diagrammatic Graphical
     Language for Bioregulatory Networks. [Science]{.underline} STKE
     2004; 222: pe8.

216. Roschke, A.V., Lababidi, S., Tonon, G., Gehlhaus, K.S., Weinstein,
     J.N., and Kirsch, I.R. Chromosomal "state" as a potential target
     for cancer therapy. [Proc. Natl. Acad. Sci. U.S.A.]{.underline}
     2005; 102: 2964-2969.

217. Lotze, M.T., Wang, E., Marincola, F., Hanna, N., Panelli, M.C.,
     Weinstein, J.N., Perricone, M.A., Shivers, S.C., Bugelski, J.,
     Sauter, G., Burns, C.A., Howell, M., Damle, N., Taylor, L.,
     Godfrey, T., Petricoin, E., Scheibenbogen, C., Whiteside, T.L., and
     Coukos, G. Identifying Biomarkers and Surrogates of Tumors in
     Patients, [J. Immunother.]{.underline} 2005; 28: 79-119.

218. Stevens, E.V., Nishizuka, S., Antony, S., Reimers, M., Young, L.,
     Munson, P.J., Weinstein, J.N., Kohn, E.C., and Pommier, Y. A novel
     proteomic approach for predicting cisplatin and Et-743 drug
     sensitivity. [J. Exptl. Med.]{.underline}, submitted.

219. Petersen, D., Gadisetti, C., Geoghegan, J., Hilburn, J., Paarlberg,
     J., Kim, C.H., Munroe, D., Gangi, L. Han, J., Puri, R., Staudt, L.,
     Weinstein, J.N., Barrett, J.C., Green, J., and Kawasaki, E.S. Three
     microarray platforms: An analysis of their concordance in profiling
     gene expression. [BMC Genomics]{.underline} 2005; 6: 63.

220. Fojo, T., Farrell, N., Ortuzar, W., Tanimura, H., Weinstein, J.N.,
     Myers, T.G. Identification of non-cross-resistant platinum
     compounds with novel cytotoxicity profiles using the NCI anticancer
     drug screen and clustered image map visualizations, [Crit. Rev.
     Hematol./Oncol]{.underline}. 2005; 53: 25-34.

221. Zeeberg, B.R., Qin, H., Narasimhan, S., Sunshine, M., Cao, H.,
     Kane, D.W., Reimers, M., Stephens, R.M., Bryant, D., Burt, S.K.,
     Elnekave, E., Hari, D.M., Wynn, T.A., Cunningham-Rundles, C.,
     Stewart, D.M., Nelson, D., and Weinstein, J.N. High-Throughput
     GoMiner, an "industrial-strength" Gene Ontology tool for
     interpretation of multiple-microarray experiments, with application
     to studies of Common Variable Immune Deficiency (CVID), [BMC
     Bioinformatics]{.underline} 2005; 6:168.

222. Reimers, M. and Weinstein, J.N.. Quality assessment of microarrays:
     Visualization of spatial artifacts and quantitation of regional
     biases, [BMC Bioinformatics]{.underline} 2005; 6:166.

223\. Ludwig, J.A. and Weinstein, J.N: Biomarkers in cancer staging,
prognosis, and treatment selection. [Nature Reviews Cancer]{.underline}
2005; 5: 845-856.

224\. Ule, J., Ule, A., Spencer, J., Williams, A., Hu, J.-S., Cline, M.,
Wang, H., Clark, T., Fraser, C., Ruggiu, M., Zeeberg, B., Weinstein,
J.N., Blume, J., and Darnell, R.B.: Nova regulates brain-specific
splicing to shape the synapse, [Nature Genetics]{.underline} 2005; 37:
844-852.

225\. Staib, F., Robles, A.I., Varticovski, L., Wang, Sirotin, M.,
Zhurkin, V.B., Hofseth, L.J., Hussain, S.P., Galle, P.R., Zeeberg, B.,
Weinstein, J.N., and Harris, C.C. The p53 tumor suppressor network
microenvironment components of chronic inflammation stress, [Cancer
Res.]{.underline} 2005; 65; 10255-10264.

226\. Bussey, K.J., Chin, K., Lababidi, S., Reinhold, W.C., Kuo, W.-L.,
Gwadry, F., Ajay, Kouros-Mehr, H., Fridlyand, J., Jain, A., Collins, C.,
Nishizuka, S., Tonon, G., Roschke, A., Gehlhaus, K., Kirsch, I.,
Scudiero, D.A., Reimers, M., Gray, J., and Weinstein, J.N.: Integrating
data on DNA copy number with gene expression levels and drug
sensitivities in the NCI-60 cell line panel, [Molecular Cancer
Therapeutics]{.underline} 2006; 5: 853-867.

227\. Major, S.M., Nishizuka, S., Morita, D., Rowland, Sunshine, M.,
Shankavaram, U., Washburn, F., Asin, D., Kouros-Mehr, H., Kane, D., and
Weinstein, J.N. AbMiner: An information resource of validated antibodies
and corresponding gene identifiers for genomic, proteomic, and
immunologic studies. [BMC Bioinformatics]{.underline} 2006;7: 192.

228\. Blower, P.E., Cross, K.C., Eichler, G.S., Myatt, G.J., Weinstein,
J.N., and Yang, C. Comparison of methods for sequential screening of
large compound sets, [Comb. Chem. High Throughput Screen]{.underline}
2006; 9: 115-122.

229\. Ludwig, J.A., Szakacs, G., Martin, S.E., Chu, B.F., Cardarelli,
C., Sauna, Z.E., Caplen, N.J., Fales, H.M., Ambudkar, S.V., Weinstein,
J.N., and Gottesman, M.M. Selective toxicity of NSC 73306 in
MDR1-positive cells as a new strategy to circumvent multidrug resistance
in cancer. [Cancer Research]{.underline} 2006; 66: 4808-4815.

230\. Morin, R.D., [Chang,
E](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Chang+E"%5BAuthor%5D).,
[Petrescu,
A](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Petrescu+A"%5BAuthor%5D).,
[Liao,
N](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Liao+N"%5BAuthor%5D).,
[Griffith,
M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Griffith+M"%5BAuthor%5D).,
[Kirkpatrick,
R](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Kirkpatrick+R"%5BAuthor%5D).,
[Butterfield,
Y.S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Butterfield+YS"%5BAuthor%5D).,
[Young,
A.C](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Young+AC"%5BAuthor%5D).,
[Stott,
J](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Stott+J"%5BAuthor%5D).,
[Barber,
S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Barber+S"%5BAuthor%5D).,
[Babakaiff,
R](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Babakaiff+R"%5BAuthor%5D).,
[Dickson,
M.C](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Dickson+MC"%5BAuthor%5D).,
[Matsuo,
C](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Matsuo+C"%5BAuthor%5D).,
[Wong,
D](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Wong+D"%5BAuthor%5D).,
[Yang,
G.S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Yang+GS"%5BAuthor%5D).,
[Smailus,
D.E](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Smailus+DE"%5BAuthor%5D).,
[Wetherby,
K.D](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Wetherby+KD"%5BAuthor%5D).,
[Kwong,
P.N](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Kwong+PN"%5BAuthor%5D).,
[Grimwood,
J](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Grimwood+J"%5BAuthor%5D).,
[Brinkley, C.P.
3rd](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Brinkley+CP+3rd"%5BAuthor%5D),
[Brown-John,
M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Brown-John+M"%5BAuthor%5D).,
[Reddix-Dugue,
N.D](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Reddix-Dugue+ND"%5BAuthor%5D).,
[Mayo,
M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Mayo+M"%5BAuthor%5D).,
[Schmutz,
J](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Schmutz+J"%5BAuthor%5D).,
[Beland,
J](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Beland+J"%5BAuthor%5D).,
[Park,
M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Park+M"%5BAuthor%5D).,
[Gibson,
S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Gibson+S"%5BAuthor%5D).,
[Olson,
T](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Olson+T"%5BAuthor%5D).,
[Bouffard,
G.G](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Bouffard+GG"%5BAuthor%5D).,
[Tsai,
M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Tsai+M"%5BAuthor%5D).,
[Featherstone,
R](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Featherstone+R"%5BAuthor%5D).,
[Chand,
S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Chand+S"%5BAuthor%5D).,
[Siddiqui,
A.S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Siddiqui+AS"%5BAuthor%5D).,
[Jang,
W](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Jang+W"%5BAuthor%5D).,
[Lee,
E](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Lee+E"%5BAuthor%5D).,
[Klein,
S.L](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Klein+SL"%5BAuthor%5D).,
[Blakesley,
R.W](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Blakesley+RW"%5BAuthor%5D).,
[Zeeberg,
B.R](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Zeeberg+BR"%5BAuthor%5D).,
[Narasimhan,
S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Narasimhan+S"%5BAuthor%5D).,
[Weinstein,
J.N](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Weinstein+JN"%5BAuthor%5D).,
[Prange, Pennacchio,
C](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Prange+Pennacchio+C"%5BAuthor%5D).,
[Myers,
R.M](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Myers+RM"%5BAuthor%5D).,
[Green,
E.D](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Green+ED"%5BAuthor%5D).,
[Wagner,
L](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Wagner+L"%5BAuthor%5D).,
[Gerhard,
D.S](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Gerhard+DS"%5BAuthor%5D).,
[Marra,
M.A](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Marra+MA"%5BAuthor%5D).,
[Jones,
S.J](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Jones+SJ"%5BAuthor%5D).,
and [Holt,
R.A](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term="Holt+RA"%5BAuthor%5D).
Sequencing and analysis of 10,967 full-length cDNA clones from *Xenopus
laevis* and *Xenopus tropicalis* reveals post-tetraploidization
transcriptome remodeling, [Genome Res.]{.underline} 2006; 16: 796-803.

231\. Kohn, K.W., Aladjem, M.I., Weinstein, J.N., Pommier, Y. Molecular
interaction maps of bioregulatory networks: a general rubric for systems
biology. [Mol. Biol Cell]{.underline} 2006; 17: 1-13.

232\. Simmons, S., Zeeberg, B.R., Bussey, K.J., Major, S., Nishizuka,
S., Kohn, K.W., Aladjem, M., Pommier, Y., Shankavaram, U., Tanabe, L.,
Smith, L.H., Kim, S., Reimers, M., Kane, D., Weinstein, J.N. Integromic
analysis of diverse molecular. databases: The 'Miner Suite' of
bioinformatic tools, [Chance]{.underline}, in press.

233\. Pommier, Y., Weinstein, J.N., Aladjem, M.I., Kohn, K.W. Chk2
molecular interaction map and rationale for Chk2 inhibitors, [Clinical
Cancer Res.]{.underline} 2006; 12: 2657-2661.

234\. Ikediobi, O.N., Edkins, S., Stevens, C., O'Meara, S., Bignell, G.,
Teague, J., Butler, A., Buck, G., Gray, K., Halliday, K., Kosmidou, V.,
Lugg, R., Menzies, A., Perry, J., Petty, R., Raine, K., Shepherd, R.,
Small, A., Widaa, S., Varian, J., Reinhold, W., Weinstein, J.N.,
Stratton, M.R., Futreal, P.A., and Wooster, R. DNA sequence analysis of
32 known cancer genes in the NCI-60 cell lines. [Molecular Cancer
Therapeutics,]{.underline} in press.

235\. Reinhold, W.C., Reimers, M., Maunakea, A.K., Kim, S., Lababidi,
S., Scherf, U., Ziegler, M.S., Steward, C., Kouros-Mehr, H., Cui, H.,
Bussey, K.J., Chin, K., Gray, J., Dolginow, D., Nishizuka, S., Scudiero,
D.A., Pommier, Y., Munroe, D.J., Feinberg, A., and Weinstein, J.N.:
E-cadherin in the NCI-60 cancer cells: Integrating DNA methylation
status with mRNA and protein expression, DNA copy number, and
transcription factors. [Cancer Research]{.underline}, submitted.

236\. Riss, J., Khanna, C., Koo, S., Gadisetti, V.R., Chandramouli, H.,
Yang, H., Hu, Y., Kleiner, D.E., Rosenwald, A., Schaefer, C.F.,
Ben-Sasson, S.A., Yang, L., Powell, J., Kane, D.W., Star, R.A.,
Aprelikova, O., Bauer, K., Vasselli, J.R., Maranchie, J.K., Kohn, K.W.,
Zeeberg, B.R., Buetow, K.H., Linehan, W.M., Weinstein, J.N., Lee, M.P.,
Klausner, R.D., and Barrett, J.C. Cancers as Wounds that Do Not Heal:
Similarities and Differences between Renal Regeneration and Renal Cell
Carcinoma. [Cancer Research]{.underline} 2006; 66: 7216-7224.

237\. Lorenzi, P.L., Reinhold, W.C., Rudelius, M., Gunsior, M.,
Shankavaram, U., Bussey, K.J., Scherf, U., Eichler, G.S., Martin, S.E.,
Chin, K., Gray, J.W., Kohn, E.C., Horak, I.D., Von Hoff, D.D., Raffeld,
M., Goldsmith, P.K., Caplen, N.J., and Weinstein, J.N. Asparagine
synthetase as a causal, predictive biomarker for L-asparaginase activity
in ovarian cancer cells. [Molec. Cancer Therapeutics]{.underline}, in
press.

238\. Meng, L.-H., Shankavaram, U., Chen, C., Agama, K., Fu, H.-Q.,
Gonzalez, F.J., Weinstein, J.N., and Pommier, Y. Activation of
aminoflavone (NSC 686288) by a sulfotransferase is required for the
drug's antiproliferative effect and for induction of histone gamma-H2AX.
[Cancer Res.]{.underline}, in press.

239\. Lee, J.K., Havaleshko, D.M., Cho, H.J., Weinstein, J.N.,
Karpovich, J., Grimshaw, A., and Theodorescu, D. A new strategy for
predicting the chemosensitivity of human cancers and its application to
drug discovery. [Nature]{.underline}, submitted.

240\. Martin, S.E., Jones, T.L., Thomas, C.L., Lorenzi, P.L., Nguyen,
D.A., Runfola, T., Gunsior, M., Weinstein, J.N., Goldsmith, P.K., Lader,
E., Huppi, K., and Caplen, N.J. Increased efficiency of synthetic siRNA
screens using multiplexed, multi-gene RNA interference in human cells.
[Nature Methods]{.underline}, submitted.

241\. Kahn, A.B., Ryan, M.C., Liu, H.-F., Zeeberg, B.R., Jamison, D.C.,
Weinstein, J.N. SpliceMiner: A High-Throughput Database Implementation
of the NCBI Evidence Viewer for Microarray Splice Variant Analysis. [BMC
Bioinformatics]{.underline}, submitted.

242\. Boersma, B.J., Reimers, M., Yi, M., Ludwig, J.A., Luke, B.T.,
Stephens, R.M., Yfantis, H.G., Lee, D.H., Weinstein, J.N., and Ambs, S.
The stromal gene expression signature is associated with inflammatory
breast cancer and disease outcome. [J. Natl. Cancer Inst.]{.underline},
submitted.

243\. Ben-Dor, A, Lipson, D., Tsalenko, A., Baumbusch, L., Barrett,
M.M., Weinstein, J.N., Reimers, M., Boressen-Dale, A.-L., Yakhini, Z.
Framework for identifying common aberrations in DNA copy number data.
[RECOMB]{.underline}, submitted.

244\. Shankavaram, U., Reinhold, W.C., Nishizuka, S., Major, S., Morita,
d., Reimers, M., Chary, K., Scherf, U., Kahn, A., Dolginow, D., Cossman,
J., Kaldjian, E., Scudiero, D.A., Petricoin, E., Liotta, L., Lee, J.K.,
and Weinstein, J.N. Transcript and protein expression profiles of the
NCI-60 cancer cell panel: An integromic microarray study. [Molecular
Cancer Therapeutics]{.underline}, submitted.

245\. Weinstein, J.N. Spotlight on molecular profiling: 'integromic'
analysis of the NCI-60 cancer cell lines. [Molecular Cancer
Therapeutics]{.underline}, in press.

246\. Weinstein, J.N. and Pommier, Y. Connecting genes, drugs, and
diseases: Filling the pipelines? [Nature Biotechnol.]{.underline}, in
press.

247\. Weinstein, J.N. Molecular targets in the NCI-60 cancer cell lines:
A case study in integrative systems biology and pharmacology. [Nature
Reviews Cancer]{.underline}, submitted (invited).

Bibliography includes 14 publications in Science (10 as first author)