**Testing of Certain High Production Volume Chemicals; Second Group of
Chemicals**

***(Exposure Findings Supporting Information)***

U.S. Environmental Protection Agency

Office of Pollution Prevention and Toxics

Economics, Exposure and Technology Division

July 2008

**Table of Contents**

PREFACE

[[1.0]{.smallcaps} [Data Source Descriptions
3]{.smallcaps}](#data-source-descriptions)

[2.0 Summary of HPV2 Chemicals and Findings
4](#summary-of-hpv2-chemicals-and-findings)

[**Attachment A - NLM Printouts** A-1](#__RefHeading___Toc175984751)

[**Attachment B -- NOES Printouts** B-2](#__RefHeading___Toc175984753)

[**Attachment C -- TRI Printout** C-3](#__RefHeading___Toc175984755)

Preface

This findings document was prepared to support EPA's Proposed TSCA
Section 4 Test Rule for Certain High Production Volume Chemicals; Second
Group of Chemicals. Prior to promulgating a test rule under section 4 of
the Toxic Substances Control Act (TSCA), 15 U.S.C. §§2601 *et seq*, EPA
is required to make certain findings identified in section 4(a) of TSCA
relating to the chemical's risk and potential exposure, the sufficiency
of data to allow EPA to determine the human health or environmental
effects of the chemical, and the need to conduct testing.

Under TSCA section 4(a)(1)(B), EPA must make the following findings to
support a test rule based on concerns for exposure: (1) that a chemical
substance is or will be produced in substantial quantities and that it
enters or may reasonably be anticipated to enter the environment in
substantial quantities and/or that there is or may be substantial and/or
significant human exposure to such substance; (2) that there are
insufficient data and experience upon which the effects of the
manufacture, distribution in commerce, processing, use or disposal of
such substance or mixture or of any combination of such activities on
health or the environment can reasonably be determined or predicted; and
(3) that testing of the substance or mixture with respect to such
effects is necessary to develop such data. The criteria and standards
used by EPA for evaluating the terms "substantial production,"
"substantial release," and "substantial or significant human exposure"
as used in TSCA section 4(a)(1)(B)(i) are explained in EPA's Final
Statement of Policy; Criteria for Evaluating Substantial Production,
Substantial Release, and Substantial or Significant Human Exposure set
forth at 58 FR 28736 (May 14, 1993) (hereinafter referred to as the "B
Policy").

This document provides a detailed discussion of EPA's evaluation of each
of the chemical substances identified in the proposed test rule to
determine that preliminary TSCA section 4(a)(1)(B) findings concerning
"substantial production," "substantial release," and "substantial or
significant human exposure" can be made.

# Data Source Descriptions

**TSCA Inventory Update Reporting Rule**: In 1986, EPA promulgated the
Inventory Update Reporting (IUR) regulations, under TSCA section 8(a),
to facilitate the periodic updating of the TSCA Inventory database and
to otherwise support activities associated with implementing TSCA. As
originally promulgated, the IUR required chemical manufacturers
(including importers) to report to EPA every 4 years the identity of
chemical substances manufactured (including imported) annually in
quantities of 10,000 pounds or more at each plant site they owned or
controlled. In 2003 EPA adjusted the universe of chemicals and plant
sites that are required to report, and the type of information reported.
In 2005, EPA changed the reporting frequency to once every 5 years,
revised the manner in which amounts of a chemical substance manufactured
or imported must be reported, and changed the submission period for
reporting after 2006.

To protect the claims of confidential business information (CBI)
asserted by some IUR submitters on the amount of the chemical substance
manufactured (including imported) at a specific site, all production
volumes reported by IUR submitters (i.e., CBI and non-CBI) for each
chemical are combined by EPA for an aggregate total. Confidential
business information claims are further protected by using eight ranges
to identify the total for any specific chemical and then making
available to the public the range that corresponds to the aggregate
production volume. Publicly-available information from the 1986, 1990,
1994, 1998, and 2002 (and 2006) IUR reporting cycles are available
on-line at:
[[http://www.epa.gov/oppt/iur/index.htm]{.underline}](http://www.epa.gov/oppt/iur/index.htm)

The **Toxics Release Inventory (TRI)** contains information about
releases of certain chemicals and management of wastes at a wide variety
of sources, including manufacturing operations, certain service
businesses, and federal facilities. Publicly-available information from
the 2005 TRI reporting cycle is available on-line at:
[[http://www.epa.gov/triexplorer/]{.underline}](http://www.epa.gov/triexplorer/)

The National Institute for Occupational Safety and Health (NIOSH)
conducted the **National Occupational Exposure Survey (NOES)** that
collected data on potential occupational exposures to chemical,
physical, and biological agents from 1981 to 1983. The survey involved
on-site visits to 4,490 establishments in 522 industry types employing
approximately 1,800,000 workers in 377 occupational categories.
Publicly-available information from the NOES is available on-line at:
[[http://www.cdc.gov/noes/default.html]{.underline}](http://www.cdc.gov/noes/default.html)

The **National Library of Medicine Household Products Database**
provides information on the chemical ingredients and their percentage in
specific brands of household products. Information in the database is
from a variety of publicly available sources including brand-specific
labels and Material Safety Data Sheets when available from manufacturers
and manufacturers\' web sites. Publicly-available information from the
database is available on-line at:
[[http://householdproducts.nlm.nih.gov/]{.underline}](http://householdproducts.nlm.nih.gov/)

# Summary of HPV2 Chemicals and Findings

Table 2-1 below presents a summary of the high production volume (HPV)
chemicals and data collected to support an exposure-based finding. Table
2-2 presents a chemical-by-chemical explanation of the supporting
findings information.

Table 2-1

Summary of Data Searched for Exposure Based Findings

<table>
<colgroup>
<col style="width: 7%" />
<col style="width: 13%" />
<col style="width: 7%" />
<col style="width: 7%" />
<col style="width: 12%" />
<col style="width: 6%" />
<col style="width: 9%" />
<col style="width: 6%" />
<col style="width: 7%" />
<col style="width: 6%" />
<col style="width: 15%" />
</colgroup>
<thead>
<tr class="header">
<th><strong>CAS#</strong></th>
<th><strong>Chemical Name</strong></th>
<th><strong>IUR Number of Workers Information</strong></th>
<th><strong>NOES</strong></th>
<th><strong>NLM Household Chemicals Database</strong></th>
<th><strong>2005 TRI Data(Total On- and Off-site Disposal or Other
Releases, lbs)</strong></th>
<th><p><strong>2006 IUR Production Volume</strong></p>
<p><strong>[Million lbs]</strong></p></th>
<th><p><strong>Meet Exposure Based Criteria</strong></p>
<p><strong>For Workers</strong></p></th>
<th><strong>Meet Exposure Based Criteria for Consumers</strong></th>
<th><strong>Meet Exposure Based Criteria for Release</strong></th>
<th><strong>Non-CBI Commercial/ Consumer Code Description</strong></th>
</tr>
</thead>
<tbody>
<tr class="odd">
<td>75-07-0</td>
<td>Acetaldehyde</td>
<td>&gt; 1,000</td>
<td>216,533</td>
<td>3 hobby/craft glues; 1 home maintenance product</td>
<td>13,567,452</td>
<td>&gt; 100 - 500</td>
<td>Yes</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
</tr>
<tr class="even">
<td>78-11-5</td>
<td>1,3-Propanediol, 2,2-bis[(nitrooxy)methyl]-, dinitrate (ester)</td>
<td>&gt; 1,000</td>
<td>2,650</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C20 - Other</td>
</tr>
<tr class="odd">
<td>84-65-1</td>
<td>9,10-Anthracenedione</td>
<td>&gt; 1,000</td>
<td>6,187</td>
<td>no</td>
<td> </td>
<td>&gt; 10 - 50</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C13-Paper Products</td>
</tr>
<tr class="even">
<td>89-32-7</td>
<td>1H,3H-Benzo[1,2-c:4,5-c']difuran-1,3,5,7-tetrone</td>
<td>&gt; 1,000</td>
<td>1,926</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr class="odd">
<td>110-44-1</td>
<td>2,4-Hexadienoic acid, (E,E)-</td>
<td>&gt; 1,000</td>
<td>69,243</td>
<td>yes, 13 personal care products</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C16-Rubber &amp; Plastic Products, C20-Other</td>
</tr>
<tr class="even">
<td>118-82-1</td>
<td>Phenol, 4,4'-methylenebis[2,6-bis(1,1-dimethylethyl)-</td>
<td>&gt; 1,000</td>
<td>120,009</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C10-Lubricants, Greases &amp; Fuel Additives</td>
</tr>
<tr class="odd">
<td>119-61-9</td>
<td>Methanone, diphenyl-</td>
<td>&gt; 1,000</td>
<td>41,516</td>
<td>5 personal care products; 1 auto product</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C05-Electtrical &amp; Electronic Products, C12-Paints &amp;
Coatings,C13-Paper Products, C20 - Other</td>
</tr>
<tr class="even">
<td>144-62-7</td>
<td>Ethanedioic acid</td>
<td>&gt; 1,000</td>
<td>142,000</td>
<td>4 auto products; 1 brass polish; 1 cleanser; 2 wood brighteners; 1
bathroom cleanser</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td>Yes</td>
<td>C06-Fabrics, Textiles, &amp; Apparel, C07-Glass &amp; Ceramic
Products,C13-Paper Products, C15-Polishes &amp; Sanitation Goods,
C17-Soaps &amp; Detergents, C20-Other</td>
</tr>
<tr class="odd">
<td>149-44-0</td>
<td>Methanesulfunic acid, hydroxyl-, monosodium salt</td>
<td>&gt; 1,000</td>
<td>239,465</td>
<td>no</td>
<td></td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C01-Adhesives &amp; Sealants, C16-Rubber &amp; Plastics Goods</td>
</tr>
<tr class="even">
<td>2524-04-1</td>
<td>Phosphorochloridothioic acid, O,O-diethyl ester</td>
<td>&gt; 1,000</td>
<td>1,088</td>
<td>no</td>
<td> </td>
<td>&gt; 10 - 50</td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr class="odd">
<td>4719-04-4</td>
<td>1,3,5-Triazine-1,3,5(2H,4H,6H)-triethanol</td>
<td>&gt; 1,000</td>
<td>225,251</td>
<td>yes, 7 reported uses of Grotan BK (a disinfectant) in 4 laundry
detergents, 1 dishwashing detergent, 1 all purpose cleaner, and 1 glass
&amp; surface cleaner</td>
<td> </td>
<td>&gt; 10 - 50</td>
<td>Yes</td>
<td>Yes</td>
<td>Yes</td>
<td>C20-Other</td>
</tr>
<tr class="even">
<td>6381-77-7</td>
<td>D-erythro-Hex-2-enonic acid, .gamma.-lactone, monosodium salt</td>
<td>&gt; 1,000</td>
<td>19,468</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr class="odd">
<td>31138-65-5</td>
<td>D-gluco-Heptonic acid, monosodium salt, (2.xi.)-</td>
<td>&gt; 1,000</td>
<td>74,165</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>CBI</td>
</tr>
<tr class="even">
<td>66241-11-0</td>
<td>C.I. Leuco Sulphur Black 1</td>
<td>&gt; 1,000</td>
<td>38,555</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C06-Fabrics, Textiles &amp; Apparel</td>
</tr>
<tr class="odd">
<td>68187-76-8</td>
<td>Castor oil, sulfated, sodium salt</td>
<td>&gt; 1,000</td>
<td>11,164</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C17-Soaps &amp; Detergents</td>
</tr>
<tr class="even">
<td>68187-84-8</td>
<td>Castor oil, oxidized</td>
<td>&gt; 1,000</td>
<td>36,381</td>
<td>1 auto product; 1 oil-based primer/sealer; 14 personal care
products; 1 insect repellent</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td>Yes</td>
<td></td>
<td>C20-Other</td>
</tr>
<tr class="odd">
<td>68479-98-1</td>
<td>Benzenediamine, ar,ar-diethyl-ar-methyl-</td>
<td>&gt; 1,000</td>
<td>4,121</td>
<td>no</td>
<td> </td>
<td>&gt; 10 - 50</td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr class="even">
<td>68527-02-6</td>
<td>Alkenes, C12-24, chloro</td>
<td>&gt; 1,000</td>
<td>84,192</td>
<td>no</td>
<td> </td>
<td>&gt; 1 - 10</td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr class="odd">
<td>68647-60-9</td>
<td>Hydrocarbons, C&gt;4</td>
<td>&gt; 1,000</td>
<td>1,257</td>
<td>no</td>
<td> </td>
<td><em>&gt; 1Billion lbs</em></td>
<td>Yes</td>
<td></td>
<td></td>
<td></td>
</tr>
</tbody>
</table>

**Table 2-2**

**Chemical-by-Chemical Explanation of Findings**

+------+---------------+----------------------------------------------+
| CAS# | Chemical Name | Summary of Findings                          |
+======+===============+==============================================+
| 75-  | Acetaldehyde  | This chemical reports \>1 million lb release |
| 07-0 |               | to TRI. The total number of potentially      |
|      |               | exposed workers exceeds 1,000 based on       |
|      |               | reported IUR data. This chemical exceeds     |
|      |               | 1,000 workers based on NOES data.            |
|      |               | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the uses (hobby/craft glues;  |
|      |               | home maintenance product) cited in the NLM   |
|      |               | Household Chemicals Database. It is expected |
|      |               | that hobby or craft glues and home           |
|      |               | maintenance products will be widely used by  |
|      |               | consumers (including children) and hence,    |
|      |               | may likely exceed 10,000 people. Based on    |
|      |               | this information, this chemical would meet   |
|      |               | the exposure based findings criteria of      |
|      |               | \"substantial or significant human           |
|      |               | exposure." The production volume data for    |
|      |               | the 2006 IUR data collection was compared to |
|      |               | the production volume data for the 1986 IUR  |
|      |               | data collection for this chemical to see if  |
|      |               | the production volume stayed the same or     |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 500 million -1   |
|      |               | billion lbs. The 2006 IUR production volume  |
|      |               | range is 100 million -- 500 million lbs.     |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (100     |
|      |               | million -500 million lb)                     |
|      |               |                                              |
|      |               | \- Substantial Release (Greater than 13.5    |
|      |               | million lb reported to TRI)                  |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | IUR data                                     |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (217,000 workers)                  |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 78-  | 1             | The total number of potentially exposed      |
| 11-5 | ,3-Propanedio | workers exceeds 1,000 workers based on NOES  |
|      | l,2,2-bis\[(n | data. Additionally, the IUR                  |
|      | itrooxy)methy | commercial/consumer product category         |
|      | l\],dinitrate | C20-Other (*chemicals contained in           |
|      | (ester)       | commercial and consumer products not         |
|      |               | elsewhere classified*) was reported for this |
|      |               | chemical. This indicates that this chemical  |
|      |               | is present in an unknown number of           |
|      |               | commercial and consumer products that may    |
|      |               | potentially have a high number of exposures. |
|      |               | Based on this information, this chemical     |
|      |               | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -10 million lbs.  |
|      |               | The 2006 IUR production volume range is 1    |
|      |               | million -10 million lbs**.** *(All stated    |
|      |               | IUR commercial/consumer product categories   |
|      |               | are non-CBI)*                                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based NOES  |
|      |               | data                                         |
|      |               |                                              |
|      |               | (2,650 workers)                              |
+------+---------------+----------------------------------------------+
| 84-  | 9,10-An       | The total number of potentially exposed      |
| 65-1 | thracenedione | workers is likely to exceed 1,000 based on   |
|      |               | reported IUR data. The number of potentially |
|      |               | exposed total workers exceeds 1,000 based on |
|      |               | NOES data. Additionally, the number of       |
|      |               | potentially exposed consumers is estimated   |
|      |               | to be very large based on the reported IUR   |
|      |               | commercial/consumer product category for     |
|      |               | this chemical (C13 -- paper products).       |
|      |               | Chemicals reporting in this category are     |
|      |               | contained in commercial and consumer paper   |
|      |               | products. It is expected that paper products |
|      |               | will be widely used by commercial workers    |
|      |               | and consumers (including children) and       |
|      |               | hence, may likely exceed 1,000 commercial    |
|      |               | workers and 10,000 consumers. Based on this  |
|      |               | information, this chemical would meet the    |
|      |               | exposure based findings criteria of          |
|      |               | \"substantial or significant human           |
|      |               | exposure." The production volume data for    |
|      |               | the 2006 IUR data collection was compared to |
|      |               | the production volume data for the 1986 IUR  |
|      |               | data collection for this chemical to see if  |
|      |               | the production volume stayed the same or     |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 500 thousand --  |
|      |               | 1 million lbs. The 2006 IUR production       |
|      |               | volume range is 10 million -- 50 million     |
|      |               | lbs. *(All stated IUR commercial/consumer    |
|      |               | product categories are non-CBI)*             |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (10      |
|      |               | million -50 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based NOES  |
|      |               | data (6,187 workers)                         |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on IUR commercial/consumer product     |
|      |               | category (C13)                               |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 89-  | 1H,3H-Benzo\  | The total number of potentially exposed      |
| 32-7 | [1,2-c:4,5-c\ | workers exceeds 1,000 based on NOES data.    |
|      | '\]difuran-1, | Based on this information, this chemical     |
|      | 3,5,7-tetrone | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      | []{.mark}     | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs.                 |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based NOES  |
|      |               | data (1,926 workers).                        |
+------+---------------+----------------------------------------------+
| 110- | 2,            | The total number of potentially exposed      |
| 44-1 | 4-Hexadienoic | workers exceeds 1,000 based on NOES data.    |
|      | acid, (E,E)-  | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the uses cited in the NLM     |
|      |               | Household Chemicals Database (personal care  |
|      |               | products) and the reported IUR               |
|      |               | commercial/consumer product categories for   |
|      |               | this chemical (C16 -- rubber and plastic     |
|      |               | products and C20 - other). Chemicals         |
|      |               | reporting in these categories are contained  |
|      |               | in such products as tires, footwear,         |
|      |               | flooring, bottles, sporting equipment,       |
|      |               | games, and toys. It is expected that these   |
|      |               | products will be widely used by consumers    |
|      |               | (including children) and hence, may likely   |
|      |               | exceed 10,000 people. Additionally, products |
|      |               | such as tires and flooring are also used in  |
|      |               | a commercial setting, which may lead to      |
|      |               | exposures of \>1,000 commercial workers.     |
|      |               | Based on this information, this chemical     |
|      |               | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs. *(All stated    |
|      |               | IUR commercial/consumer product categories   |
|      |               | are non-CBI)*                                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (69,243 workers)                   |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on the IUR commercial/consumer product |
|      |               | categories (C16 )                            |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 118- | P             | The total number of potentially exposed      |
| 82-1 | henol,4,4\'-m | workers exceeds1,000 based on NOES data.     |
|      | ethylenebis\[ | Additionally, the number of potentially      |
|      | 2,6-bis(1,1-d | exposed consumers is estimated to be very    |
|      | imethylethyl) | large based on the reported IUR              |
|      |               | commercial/consumer product category for     |
|      |               | this chemical (C10 -- lubricants, greases, & |
|      |               | fuel additives). Chemicals reporting in this |
|      |               | category are contained in gasoline,          |
|      |               | kerosene, and distillate fuel oil after      |
|      |               | refining. These are generally commercial or  |
|      |               | consumer additives to enhance performance or |
|      |               | clean components of combustion devices. It   |
|      |               | is expected that these products will be      |
|      |               | widely used by commercial workers and        |
|      |               | consumers and hence, may likely exceed 1,000 |
|      |               | commercial workers and 10,000 consumers.     |
|      |               | Based on this information, this chemical     |
|      |               | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs. *(All stated    |
|      |               | IUR commercial/consumer product categories   |
|      |               | are non-CBI)*                                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (120,009 workers)                  |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on and the IUR commercial/consumer     |
|      |               | product category (C10)                       |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 119- | Methanone,    | The total number of potentially exposed      |
| 61-9 | diphenyl-     | workers exceeds 1,000 based on NOES data.    |
|      |               | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the uses cited in the NLM     |
|      |               | Household Chemicals Database (personal care  |
|      |               | products and auto products) and the reported |
|      |               | IUR commercial/consumer product categories   |
|      |               | for this chemical (C05 -- electrical and     |
|      |               | electronic products, C12 -- paints and       |
|      |               | coatings, C13 -- paper products, and C20 -   |
|      |               | other). Chemicals reporting in these IUR     |
|      |               | product categories are contained in          |
|      |               | computers, office equipment, household       |
|      |               | appliances, electric lighting and wiring,    |
|      |               | video and audio recording and communication  |
|      |               | equipment; commercial and consumer paints    |
|      |               | (paste or ready-mix) including artists'      |
|      |               | paints, varnishes, lacquers, enamels and     |
|      |               | shellac, paint and varnish removers and      |
|      |               | cleaners and commercial and consumer paper   |
|      |               | products. It is expected that these products |
|      |               | will be widely used by commercial workers    |
|      |               | and consumers (including children) and       |
|      |               | hence, may likely exceed 1,000 commercial    |
|      |               | workers and 10,000 consumers. Based on this  |
|      |               | information, this chemical would meet the    |
|      |               | exposure based findings criteria of          |
|      |               | \"substantial or significant human           |
|      |               | exposure." The production volume data for    |
|      |               | the 2006 IUR data collection was compared to |
|      |               | the production volume data for the 1986 IUR  |
|      |               | data collection for this chemical to see if  |
|      |               | the production volume stayed the same or     |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 1 million -- 10  |
|      |               | million lbs. The 2006 IUR production volume  |
|      |               | range is 1 million -- 10 million lbs. *(All  |
|      |               | stated IUR commercial/consumer product       |
|      |               | categories are non-CBI)*                     |
|      |               |                                              |
|      |               | []{.mark}                                    |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (41,516 workers)                   |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on the IUR commercial/consumer product |
|      |               | categories (C05, C12, C13 )                  |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 144- | Ethanedioic   | The total number of potentially exposed      |
| 62-7 | acid          | workers is likely to exceed 1,000 based on   |
|      |               | reported IUR data. The total number of       |
|      |               | potentially exposed workers exceeds 1,000    |
|      |               | based on NOES data. The number of            |
|      |               | potentially exposed consumers is estimated   |
|      |               | to be very large based on the uses cited in  |
|      |               | the NLM Household Chemicals Database (auto   |
|      |               | products, cleansers, wood brighteners, and   |
|      |               | polishes) and the reported IUR               |
|      |               | commercial/consumer product categories for   |
|      |               | this chemical (C06 -- fabrics, textiles, &   |
|      |               | apparel, C07 -- glass & ceramic products,    |
|      |               | C13 -- paper products, C15 -- polishes &     |
|      |               | sanitation goods, C17 -- soaps &             |
|      |               | detergents). Additionally, the IUR           |
|      |               | commercial/consumer product category         |
|      |               | C20-Other (*chemicals contained in           |
|      |               | commercial and consumer products not         |
|      |               | elsewhere classified*) was reported for this |
|      |               | chemical. This indicates that this chemical  |
|      |               | is present in an unknown number of           |
|      |               | commercial and consumer products that may    |
|      |               | potentially have a high number of exposures. |
|      |               | Chemicals reporting in these IUR product     |
|      |               | categories are contained in commercial and   |
|      |               | consumer products made of cotton, silk,      |
|      |               | wool, or manmade fibers; commercial and      |
|      |               | consumer glass and ceramic products;         |
|      |               | commercial and consumer paper products;      |
|      |               | furniture, metal, glass, and other polishes  |
|      |               | and cleaners; waxes and dressings for        |
|      |               | leather and other materials; household and   |
|      |               | industrial disinfectants and bleaches;       |
|      |               | liquid, granulated, caked, and flaked        |
|      |               | washing detergents and personal soaps;       |
|      |               | dishwashing compounds; presoaks and scouring |
|      |               | compounds for commercial and consumer use;   |
|      |               | and sporting equipment, games and toys. It   |
|      |               | is expected that these products will be      |
|      |               | widely used by commercial workers and        |
|      |               | consumers (including children) and hence,    |
|      |               | may likely exceed 1,000 commercial workers   |
|      |               | and 10,000 consumers. It is also expected    |
|      |               | that based on the nature of the C17 use that |
|      |               | over 90 % of the soaps & detergent products  |
|      |               | that contain this chemical will be released  |
|      |               | into the environment (exceeding the          |
|      |               | significant release threshold of 10% of the  |
|      |               | production volume). Based on this            |
|      |               | information, this chemical would likely meet |
|      |               | the exposure based findings criteria of      |
|      |               | \"substantial or significant human           |
|      |               | exposure\" and "substantial or significant   |
|      |               | release." The production volume data for the |
|      |               | 2006 IUR data collection was compared to the |
|      |               | production volume data for the 1986 IUR data |
|      |               | collection for this chemical to see if the   |
|      |               | production volume stayed the same or         |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 1 million -- 10  |
|      |               | million lbs. The 2006 IUR production volume  |
|      |               | range is 1 million -- 10 million lbs. *(All  |
|      |               | stated IUR commercial/consumer product       |
|      |               | categories are non-CBI)*                     |
|      |               |                                              |
|      |               | []{.mark}                                    |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Substantial Release based on IUR          |
|      |               | commercial/consumer product category (C17 -- |
|      |               | soaps & detergents)                          |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on IUR data                            |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (142,000 workers)                  |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 149- | Me            | The total number of potentially exposed      |
| 44-0 | thanesulfunic | workers exceeds 1,000 based on NOES data.    |
|      | acid,         | Additionally, the number of potentially      |
|      | hydrox        | exposed consumers is estimated to be very    |
|      | yl-monosodium | large based on the reported IUR              |
|      | salt          | commercial/consumer product categories for   |
|      |               | this chemical (C01 -- adhesives & sealants   |
|      |               | and C16 -- rubber and plastics goods).       |
|      |               | Chemicals reporting in these product         |
|      |               | categories are contained in industrial and   |
|      |               | household adhesives; glues; caulking         |
|      |               | compounds; sealants; linoleum, tile, and     |
|      |               | rubber cements; tires; footwear; flooring;   |
|      |               | and bottles. It is expected that these       |
|      |               | products will be widely used by commercial   |
|      |               | workers and consumers and hence, may likely  |
|      |               | exceed 1,000 commercial workers and 10,000   |
|      |               | consumers. Based on this information, this   |
|      |               | chemical would meet the exposure based       |
|      |               | findings criteria of \"substantial or        |
|      |               | significant human exposure." The production  |
|      |               | volume data for the 2006 IUR data collection |
|      |               | was compared to the production volume data   |
|      |               | for the 1986 IUR data collection for this    |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs. *(All stated    |
|      |               | IUR commercial/consumer product categories   |
|      |               | are non-CBI)*                                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (239,465 workers)                  |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on and the IUR commercial/consumer     |
|      |               | product categories (C01 and C16)             |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 2    | Phosphoro     | The total number of potentially exposed      |
| 524- | chloridthioic | workers exceeds 1,000 based on NOES data.    |
| 04-1 | acid,         | Based on this information, this chemical     |
|      | O,O-diethyl   | would meet the exposure based findings       |
|      | ester         | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 10 million -- 50 million    |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 10 million -- 50 million lbs.                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (10      |
|      |               | million -50 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based NOES  |
|      |               | data (1,088 workers).                        |
+------+---------------+----------------------------------------------+
| 4    | 1,            | The total number of potentially exposed      |
| 719- | 3,5-Triazine- | workers is likely to exceed 1,000 based on   |
| 04-4 | 1,3,5(2H,4H,6 | reported IUR data. The number of workers     |
|      | H)-triethanol | exceeds 1,000 based on NOES data.            |
|      |               | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the uses cited in the NLM     |
|      |               | Household Chemicals Database (laundry and    |
|      |               | dishwashing detergents; and all-purpose and  |
|      |               | surface cleaners). Additionally, the IUR     |
|      |               | commercial/consumer product category         |
|      |               | C20-Other (*chemicals contained in           |
|      |               | commercial and consumer products not         |
|      |               | elsewhere classified*) was reported for this |
|      |               | chemical. This indicates that this chemical  |
|      |               | is present in an unknown number of           |
|      |               | commercial and consumer products that may    |
|      |               | potentially have a high number of exposures. |
|      |               | It is expected that these products will be   |
|      |               | widely used by consumers (including          |
|      |               | children) and hence, may likely exceed       |
|      |               | 10,000 people. Additionally, products such   |
|      |               | as laundry detergents and all-purpose        |
|      |               | surface cleaners may be used by commercial   |
|      |               | enterprises that may lead to exposures of    |
|      |               | \>1,000 commercial workers. It is also       |
|      |               | expected that based on the nature of the     |
|      |               | laundry and dishwashing detergents use       |
|      |               | described in the NLM Household Chemicals     |
|      |               | Database that over 90 % of the production    |
|      |               | volume of the soaps & detergent products     |
|      |               | that contain this chemical will be released  |
|      |               | into the environment (exceeding the          |
|      |               | significant release threshold of 10% of the  |
|      |               | production volume). Based on this            |
|      |               | information, this chemical would meet the    |
|      |               | exposure based findings criteria of          |
|      |               | \"substantial or significant human           |
|      |               | exposure\" and "significant or substantial   |
|      |               | release." The production volume data for the |
|      |               | 2006 IUR data collection was compared to the |
|      |               | production volume data for the 1986 IUR data |
|      |               | collection for this chemical to see if the   |
|      |               | production volume stayed the same or         |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 1 million -- 10  |
|      |               | million lbs. The 2006 IUR production volume  |
|      |               | range is 10 million -- 50 million lbs. *(All |
|      |               | stated IUR commercial/consumer product       |
|      |               | categories are non-CBI)*                     |
|      |               |                                              |
|      |               | []{.mark}                                    |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (10      |
|      |               | million -50 million lb)                      |
|      |               |                                              |
|      |               | \- Substantial Release (Greater than 10% of  |
|      |               | production volume released)                  |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on NLM Household Chemicals Database    |
|      |               | information                                  |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based on NOES |
|      |               | data (225,251 workers)                       |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 6    | D-erythro     | The total number of potentially exposed      |
| 381- | -Hex-2-enonic | workers exceeds 1,000 based on NOES data.    |
| 77-7 | acid,.ga      | Based on this information, this chemical     |
|      | mma.-lactone, | would meet the exposure based findings       |
|      | monosodium    | criteria of \"substantial or significant     |
|      | salt          | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      | []{.mark}     | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 10 thousand -- 500 thousand |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs.                 |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based NOES    |
|      |               | data (19,468 workers).                       |
+------+---------------+----------------------------------------------+
| 31   | D-g           | The total number of potentially exposed      |
| 138- | luco-Heptonic | workers exceeds 1,000 based on NOES data.    |
| 65-5 | acid,         | Based on this information, this chemical     |
|      | monosodium    | would meet the exposure based findings       |
|      | salt,         | criteria of \"substantial or significant     |
|      | (2.xi.)-      | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs.                 |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based NOES  |
|      |               | data (74,165 workers).                       |
+------+---------------+----------------------------------------------+
| 66   | C.I. Leuco    | The total number of potentially exposed      |
| 241- | Sulphur Black | workers exceeds 1,000 based on NOES data.    |
| 11-0 | 1             | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the reported IUR              |
|      |               | commercial/consumer product category for     |
|      |               | this chemical (C06 -- fabrics, textiles      |
|      |               | &apparel). Chemicals reporting in this       |
|      |               | category are contained in commercial and     |
|      |               | consumer products made of cotton, silk,      |
|      |               | wool, or manmade fibers. It is expected that |
|      |               | these products will be widely used by        |
|      |               | commercial workers and consumers (including  |
|      |               | children) and hence, may likely exceed 1,000 |
|      |               | commercial workers and 10,000 consumers.     |
|      |               | Based on this information, this chemical     |
|      |               | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 1 million -- 10 million     |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 1 million -- 10 million lbs. *(All stated    |
|      |               | IUR commercial/consumer product categories   |
|      |               | are non-CBI)*                                |
|      |               |                                              |
|      |               | []{.mark}                                    |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (38,555 workers)                   |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on reported IUR commercial/consumer    |
|      |               | product category (C06 -- fabrics & textiles) |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 68   | Castor oil,   | The total number of potentially exposed      |
| 187- | sulfated,     | workers exceeds 1,000 based on NOES data.    |
| 76-8 | sodium salt   | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the reported IUR              |
|      |               | commercial/consumer product category for     |
|      |               | this chemical (C17 -- soaps & detergents).   |
|      |               | Chemicals reporting in this category are     |
|      |               | contained in liquid, granulated, caked, and  |
|      |               | flaked washing detergents and personal       |
|      |               | soaps; dishwashing compounds; and presoaks   |
|      |               | and scouring compounds for commercial and    |
|      |               | consumer use. It is expected that these      |
|      |               | products will be widely used by commercial   |
|      |               | workers and consumers and hence, may likely  |
|      |               | exceed 1,000 commercial workers and 10,000   |
|      |               | consumers. The production volume data for    |
|      |               | the 2006 IUR data collection was compared to |
|      |               | the production volume data for the 1986 IUR  |
|      |               | data collection for this chemical to see if  |
|      |               | the production volume stayed the same or     |
|      |               | increased, thereby indicating that the usage |
|      |               | of these chemicals is no less than when NOES |
|      |               | data were gathered. The 1986 reported IUR    |
|      |               | production volume range was 1 million -- 10  |
|      |               | million lbs. The 2006 IUR production volume  |
|      |               | range is 1 million -- 10 million lbs. *(All  |
|      |               | stated IUR commercial/consumer product       |
|      |               | categories are non-CBI)*                     |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeding 1,000 based on    |
|      |               | NOES data (11164 workers)                    |
|      |               |                                              |
|      |               | \- Total workers potentially exceeding 1,000 |
|      |               | based on IUR commercial/consumer product     |
|      |               | category (C17 - soaps & detergents)          |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 68   | Castor oil,   | The total number of potentially exposed      |
| 187- | oxidized      | workers exceeds 1,000 based on NOES data.    |
| 84-8 |               | Additionally, the number of potentially      |
|      |               | exposed consumers is estimated to be very    |
|      |               | large based on the uses cited in the NLM     |
|      |               | Household Chemicals Database (auto care      |
|      |               | products and personal care products).        |
|      |               | Additionally, the IUR commercial/consumer    |
|      |               | product category C20-Other (*chemicals       |
|      |               | contained in commercial and consumer         |
|      |               | products not elsewhere classified*) was      |
|      |               | reported for this chemical. This indicates   |
|      |               | that this chemical is present in an unknown  |
|      |               | number of commercial and consumer products   |
|      |               | that may potentially have a high number of   |
|      |               | exposures. It is expected that these         |
|      |               | products will be widely used by consumers    |
|      |               | (including children) and hence, may likely   |
|      |               | exceed 10,000 people. Additionally, products |
|      |               | such as auto care products may be used by    |
|      |               | commercial enterprises that may lead to      |
|      |               | exposures of \>1,000 commercial workers.     |
|      |               | Based on this information, this chemical     |
|      |               | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. There were no reports for this     |
|      |               | chemical for the 1986 IUR data collection.   |
|      |               | The 2006 IUR production volume range is 1    |
|      |               | million -- 10 million lbs. *(All stated IUR  |
|      |               | commercial/consumer product categories are   |
|      |               | non-CBI)*                                    |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based on NOES |
|      |               | data (36,381workers)                         |
|      |               |                                              |
|      |               | \- Total workers potentially exceeds 1,000   |
|      |               | based on NLM Household Chemicals Database    |
|      |               | information                                  |
|      |               |                                              |
|      |               | \- Consumers potentially exceeding 10,000    |
|      |               | people.                                      |
+------+---------------+----------------------------------------------+
| 68   | Be            | The total number of potentially exposed      |
| 479- | nzenediamine, | workers exceeds1,000 based on NOES data.     |
| 98-1 | ar,ar-dieth   | Based on this information, this chemical     |
|      | yl-ar-methyl- | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 10 million -- 50 million    |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | 10 million -- 50 million lbs.                |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (10      |
|      |               | million -50 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based NOES    |
|      |               | data (4,121 workers).                        |
+------+---------------+----------------------------------------------+
| 68   | Alkenes,      | The total number of potentially exposed      |
| 527- | C12-24,       | workers exceeds 1,000 workers based on NOES  |
| 02-6 | chloro        | data. Based on this information, this        |
|      |               | chemical would meet the exposure based       |
|      | []{.mark}     | findings criteria of \"substantial or        |
|      |               | significant human exposure." The production  |
|      |               | volume data for the 2006 IUR data collection |
|      |               | was compared to the production volume data   |
|      |               | for the 1986 IUR data collection for this    |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. There were no IUR reports for this |
|      |               | chemical in 1986. The 2006 IUR production    |
|      |               | volume range for this chemical is 1 million  |
|      |               | -10 million lbs.                             |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range (1       |
|      |               | million -10 million lb)                      |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based NOES    |
|      |               | data (84,192 workers).                       |
+------+---------------+----------------------------------------------+
| 68   | Hydrocarbons, | The total number of potentially exposed      |
| 647- | C\>4          | workers exceeds 1,000 based on NOES data.    |
| 60-9 |               | Based on this information, this chemical     |
|      | []{.mark}     | would meet the exposure based findings       |
|      |               | criteria of \"substantial or significant     |
|      |               | human exposure." The production volume data  |
|      |               | for the 2006 IUR data collection was         |
|      |               | compared to the production volume data for   |
|      |               | the 1986 IUR data collection for this        |
|      |               | chemical to see if the production volume     |
|      |               | stayed the same or increased, thereby        |
|      |               | indicating that the usage of these chemicals |
|      |               | is no less than when NOES data were          |
|      |               | gathered. The 1986 reported IUR production   |
|      |               | volume range was 100 million -500 million    |
|      |               | lbs. The 2006 IUR production volume range is |
|      |               | \> 1 billion lb.                             |
|      |               |                                              |
|      |               | This chemical met exposure based findings    |
|      |               | criteria based on:                           |
|      |               |                                              |
|      |               | \- 2006 IUR Production Volume Range          |
|      |               | (\>1billion lb)                              |
|      |               |                                              |
|      |               | \- Total workers exceeds 1,000 based NOES    |
|      |               | data (1,257 workers).                        |
+------+---------------+----------------------------------------------+

**Attachment A**

**Attachment B**

**Attachment C**