National Research Initiative Competitive Grants Program

FY 2008 Request for Applications

U.S. Department of Agriculture

Cooperative State Research, Education, and Extension Service

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**NRI REQUIRES ELECTRONIC SUBMISSION FOR ALL APPLICATIONS**

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Initial Announcement

This Request for Applications (RFA) is being released prior to the
passage of the Fiscal Year (FY) 2008 Agricultural Appropriations Act in
response to requests from our applicant community, as well as the need
to continue to fund critical agricultural research and integrated
programs. However, the enactment of the FY 2008 Appropriation Act and
passage of the 2007 Farm Bill may not only impact the overall level of
funding for the National Research Initiative (NRI) program, but also the
overall research and integrated grant portfolio. Hence, the Cooperative
State Research, Education, and Extension Service (CSREES) reserves the
right to amend, delete, or otherwise alter any programs. As indicated in
the title of this RFA, this is an initial announcement for the NRI
Program and, depending on the FY 2008 Appropriation Act, CSREES may be
issuing a supplemental RFA to address topics already identified in this
RFA. The Integrated Research, Education, and Extension Competitive
Grants Programs are not included in the RFA. A separate RFA will be
issued to solicit applications for those programs. Updated information
about this RFA will be made available at
[**http://www.csrees.usda.gov/fo/nri.html**](http://www.csrees.usda.gov/fo/nri.html).

**Executive Summary:**

> CSREES requests applications for the NRI Program for FY 2008 to
> support (1) high priority fundamental and mission-linked research of
> importance in the biological, environmental, physical, and social
> sciences relevant to agriculture, food, the environment, and rural
> communities and (2) competitively awarded research, extension, and
> education grants addressing key issues of national and regional
> importance to agriculture, forestry, and related topics. In FY 2008,
> CSREES anticipates that approximately \$190 million will be available
> for support of this program. Of this amount, no more than 22 percent
> will be made available to fund integrated projects. The remaining
> funds will be used to fund research projects.
>
> This notice identifies research and integrated program objectives. It
> describes separate eligibility criteria and matching requirements for
> each type of project and instructs applicants regarding the submission
> and review of applications.

**Stakeholder Input:**

> The Competitive Programs staff utilizes the input of diverse
> stakeholder groups to develop program descriptions that will solicit
> the highest-quality applications to meet the needs of U.S.
> agriculture, food, forestry, the environment, and rural communities.
> Setting program priorities is an important means of facilitating the
> scientific and technological advances needed to meet the challenges
> facing U.S. agriculture. Program priorities are developed using
> several criteria, including 1) mission relevance; 2) scientific
> opportunity; 3) impact to science and society; 4) linkages to other
> Federal programs; and 5) stakeholder input.
>
> The new stakeholder page on the CSREES Web site illustrates the
> diverse input used to generate new research and integrated priorities
> for NRI programs. The stakeholder Web page can be viewed at
> [www.csrees.usda.gov/business/reporting/stakeholder.html](http://www.csrees.usda.gov/business/reporting/stakeholder.html).
> The NRI relies on legislatively mandated guidance from the National
> Agricultural Research, Extension, Education, and Economics Advisory
> Board (NAREEEAB) as well as input from coalitions and stakeholders to
> provide a broad perspective on current research, extension, and
> education needs and priorities. The NRI staff participates in meetings
> with representatives of key commodity groups and other user groups to
> discuss stakeholders' current research priorities, to solicit comments
> and suggestions on NRI Program priorities, and to determine how the
> NRI can best meet stakeholders' needs. The NRI scientific staff
> attends scientific and professional meetings and coordinates program
> priorities with other federal agencies to ensure scientific trends are
> reflected in the RFA. In addition, the NRI receives input on its
> programs from academia, including administrators, staff members, and
> scientists at land grant and other universities.
>
> CSREES welcomes comments from any interested party for use in
> developing the next RFA for this program. Such comments will be used
> to meet the requirements of section 103(c)(2) of the Agricultural
> Research, Extension, and Education Reform Act of 1998 (7 U.S.C.
> 7613(c)(2)). This section requires the Secretary to solicit and
> consider input on a current RFA from persons who conduct or use
> agricultural research, education, and extension for use in formulating
> future RFAs for competitive programs. Comments should be submitted as
> provided in the Deadlines portion of this announcement.
>
> Written stakeholder comments should be submitted by mail to:  Policy,
> Oversight, and Funds Management Branch Staff; Office of Extramural
> Programs; USDA-CSREES; STOP 2299; 1400 Independence Avenue, SW;
> Washington, DC 20250-2299; or via e-mail to: 
> <RFP-OEP@csrees.usda.gov>. This e-mail address is intended only for
> receiving comments regarding this RFA and not requesting information
> or forms. In your comments, please state that you are responding to
> the National Research Initiative RFA.

**Deadlines:**

> **All applications must be submitted via Grants.gov by Close of
> Business (COB), which is 5:00 p.m. Eastern Time ([not local
> time]{.underline}),** on the deadline indicated in the program
> description (see Part II, E), as well as in Table 5 at the end of this
> announcement. Applications received after the applicable deadline will
> not be considered for funding. Comments regarding this RFA are
> requested within six months from the issuance of this notice. Comments
> received after this date will be considered to the extent practical.

**\*\*\*\*\*\*\*\*PLEASE READ\*\*\*\*\*\*\*\***

**Important Changes for NRI FY 2008 Application Submission**

**\*\*\*\*\*\*\*\*PLEASE READ\*\*\*\*\*\*\*\***

**Electronic Application Submission Required:**

All applications must be submitted via Grants.gov by Close of Business
(COB), which is 5:00 p.m. Eastern Time ([not local time]{.underline}),
on the deadline indicated in the program description (see Part II, E),
as well as in Table 5 at the end of this announcement. Applications
received after the applicable deadline will normally not be considered
for funding. Information about submitting an application using
grants.gov can be found in Part IV. **[All attachments must be submitted
in portable document format (PDF)]{.underline}.** Additional time may be
needed for assembling and submitting an electronic application. Please
plan accordingly. **Grants.gov does not currently support the Windows
Vista operating system. The PureEdge software used by Grants.gov for
forms may not be compatible with MS Vista.**

+-----------------------------------+----------------------------------+
| **Helpful Information for         | **Website Address**              |
| Submission**                      |                                  |
+-----------------------------------+----------------------------------+
| News, information, and resources  | [www.csrees.usda.gov/fu          |
| related to electronic submission. | nding/electronic](http://www.csr |
|                                   | ees.usda.gov/funding/electronic) |
+-----------------------------------+----------------------------------+
| All applications must be          | > [Gra                           |
| submitted through the Grants.gov  | nts.gov](http://www.grants.gov/) |
| Web site.                         |                                  |
+-----------------------------------+----------------------------------+

If you have any questions related to preparing an application for
electronic submission, contact CSREES' helpdesk:

> Email: <electronic@csrees.usda.gov>
>
> Phone: 202-401-5048, Business hours are M-F, 7:00 am -- 5:00 pm ET,
> excluding Federal holidays.

If you have any questions related to Grants.gov, contact their helpdesk:

> Email: <support@grants.gov>
>
> Toll Free: 1-800-518-4726, Business hours are M-F, 7:00 am -- 9:00 pm
> ET.

FY 2008 Appropriations:

> This RFA is being released prior to the passage of the FY 2008
> Agricultural Appropriations Act in response to requests from our
> applicant community, as well as the need to continue to fund critical
> agricultural research and integrated programs. However, the FY 2008
> Appropriations Act may not only impact the overall level of funding
> for the NRI Program, but also the overall research and integrated
> grant portfolio for FY 2008. Hence, CSREES reserves the right to
> amend, delete, or otherwise alter any programs. As indicated in the
> title of this RFA, this is an initial announcement for the NRI Program
> and depending on the FY 2008 Agricultural Appropriations Act, CSREES
> may issue a supplemental RFA to address topics already identified in
> this RFA. Updated information about this RFA will be made available at
> [**http://www.csrees.usda.gov/fo/nri.html**](http://www.csrees.usda.gov/fo/nri.html).

**Budget Restrictions Require Strict Adherence to Funding Limits:**

> Each program description details mandatory funding limits for a given
> grant type. **[Applications requesting budgets exceeding the program's
> funding limit (including indirect costs) will be returned without
> review]{.underline}.** Applicants are strongly encouraged to read the
> entire Program Description and contact the appropriate National
> Program Leader for additional information.

**Acceptance of an Application:**

> Each Program Description in the FY 2008 RFA (see Part II, E) contains
> priorities for research and/or integrated research, education, and
> extension projects and the contact information for the National
> Program Leader responsible for the program. **[The National Program
> Leader will return applications without review that exceed program
> funding limits, do not meet FY 2008 program priorities, are missing
> required documents (e.g. the Conflict of Interest list), or do not
> follow formatting guidelines (e.g. PDF attachment requirement, page
> limitations, margin size, font size, etc.]{.underline}).** See Part
> II, E for program priorities and program funding limits (including
> indirect costs) and Part IV for formatting guidelines for electronic
> submission. Please note, Grants.gov [will not]{.underline} check the
> application for agency-specific documents. Nor will Grants.gov convert
> documents to PDF or check to ensure all attached documents are saved
> in PDF format. [See Part IV of this RFA for a full list of documents
> that are required for a complete application]{.underline}.

**Letters of Intent Required for Specific Programs:**

> A letter of intent is required for 14 programs spanning 22 program
> codes in FY08. A letter of intent provides the National Program Leader
> a method to ensure applications align closely with program priorities.
> A letter of intent applies to standard research projects, integrated
> projects, standard strengthening grants, postdoctoral fellowships, and
> new investigator applications. A letter of intent is not required for
> sabbatical awards, equipment grants, conference grants, and seed
> grants.
>
> A letter of intent must follow specific deadline dates, format, and
> content outlined in the Other Key Information section of the program
> description, Part II, E. The letter of intent [must]{.underline} be
> saved in PDF format and attached to an email addressed to the
> appropriate National Program Leader with the subject heading, 'Letter
> of Intent Program\_ *program code_PD's last name*'. An acknowledgement
> receipt will be sent by email indicating the letter was received.
> Project Directors are discouraged from submitting more than one letter
> of intent per program. Project Directors who receive an invitation to
> submit a full application must do so by the program deadline. The
> invited applications will be reviewed by the program panel.
>
> Programs requiring a Letter of Intent in FY 2008

  ----------- ---------------------------------------------------------------------------
  **Program   **Program or Program Element**
  Code**      

  20.2        [Plant Biosecurity](#_C._Project_Types)

  23.1        [Managed Ecosystems](#managed-ecosystems)

  25.0        [Soil Processes](#soil-processes)

  28.0        [Air Quality](#air-quality)

  31.0        [Bioactive Food Components for Optimal
              Health](#bioactive-food-components-for-optimal-health)

  43.0        [Animal Genome (A) Translational Animal Genomics (integrated proposals
              only)](#animal-genome)

  43.0        [Animal Genome (D) Functional Genomics](#animal-genome)

  43.0        [Animal Genome (E): Whole Genome Enabled Animal Selection](#animal-genome)

  44.0        [Animal Protection and Biosecurity (A): Animal
              Disease](#animal-protection-and-biosecurity)

  51.2        [Arthropod and Nematode Biology and Management (A): Organismal and
              Population Biology](#_51.2_Arthropod_and)

  51.2        [Arthropod and Nematode Biology and Management (B): Suborganismal
              Biology](#_51.2_Arthropod_and)

  51.2        [Arthropod and Nematode Biology and Management (C): Tools, Resources, and
              Genomics](#_51.2_Arthropod_and)

  51.2        [Arthropod and Nematode Biology and Management (D): Protection of Managed
              Bees CAP](#_51.2_Arthropod_and)

  51.8        [Microbial Biology (B): Microbial Associations with
              Plants](#microbial-biology)

  51.9        [Biology of Weedy and Invasive Species in
              Agroecosystems](#biology-of-weedy-and-invasive-species-in-agroecosystems)

  52.1        [Plant Genome (D): Applied Plant Genomics Coordinated Agricultural Project
              (CAP)](#_C._Project_Types)

  56.0        [Plant Biology (A): Gene Function and Regulation](#_56.0_Plant_Biology:)

  56.0        [Plant Biology (B): Environmental Stress](#_56.0_Plant_Biology:)

  56.0        [Plant Biology (C): Biochemistry](#_56.0_Plant_Biology:)

  56.0        [Plant Biology (D): Growth and Development](#_56.0_Plant_Biology:)

  56.0        [Plant Biology (E): Plant Breeding and Education](#_56.0_Plant_Biology:)

  71.1        [Improving Food Quality and Value](#_C._Project_Types)

  71.2        [Biobased Products and Bioenergy
              Production](#biobased-products-and-bioenergy-production-research)
              [Research]{.underline}
  ----------- ---------------------------------------------------------------------------

**Program Priorities:**

> In the Project Summary, applicants must address at least one of the
> stated research or integrated priorities detailed in the program
> description of interest. Applications that do not address at least one
> of the program priorities will be returned without review.

**Integrated Projects:**

> An integrated project brings together at least two of the three
> components of the agricultural knowledge system (i.e. research,
> education, and extension) around a problem or issue. In FY 2008,
> integrated project proposals should interweave at least two of the
> three components throughout the course of the project. In general,
> strong integrated projects will be stakeholder driven, issue focused,
> and outcome based. They will exhibit a collaborative team approach,
> contain strong plans for project management and project evaluation,
> and produce sustained education/extension initiatives. Please note,
> integrated project eligibility requirements are different than for
> research applications. For more information on integrated programs in
> the NRI please visit
> <http://www.csrees.usda.gov/funding/integrated/integrated.html>.
>
> Eligibility and requirements for matching funds and types of projects
> differ by application type. Applicants are strongly encouraged to read
> the entire RFA and contact the appropriate National Program Leader
> with any questions. The NRI will use no more than 22 percent of
> available funds to support integrated research, extension, and
> education grants (see Part I, A). These funds will not be distributed
> uniformly across all NRI programs.
>
> Applications for integrated projects must include the elements of a
> logic model detailing the activities, outputs, and outcomes of the
> proposed project. This information may be provided as a narrative or
> formatted into a logic model chart. More information and resources
> related to the logic model planning process are provided at
> <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

**Social Science Research and Integrated Grant Opportunities:**

There are an increasing number of opportunities in the NRI for those
interested in funding for social science research and integrated
projects. These include the three programs with opportunities for many
different social science disciplines (Economics, Sociology, Geography,
Human Sciences, Agricultural Education, etc): 

-   Agricultural Prosperity for Small and Medium-Sized Farms (Program
    Code 66.0);

-   Agribusiness Markets and Trade (Program Code 61.0); and

-   Rural Development (Program Code 62.0).

The NRI also has opportunities for agricultural economists, rural
sociologists, and other social and behavioral scientists in topics
related to:

-   Markets for ecosystem services (Program Code 23.1);

-   Water resources (Program Code 26.0);

-   Economic efficiency of biobased products (Program Code 71.2);

-   Social, behavioral and economic factors that influence the adoption
    of practices to reduce agricultural emissions to the atmosphere
    (Program Code 28.0);

-   Economic costs of food safety regulations and its impacts on trade
    (Program Code 32.0)

-   Social and economic factors that influence obesity (Program Code
    31.5);

-   Economics of invasive species management (Program Code 51.9); and

-   Perception and acceptance of nanotechnology (Program Code 75.0)

Although some programs do not clearly identify social sciences in the
list of priorities, most integrated programs that include extension can
have opportunities in agricultural education and economic analysis. To
identify all the opportunities available for social sciences within the
NRI, it is important to review the different program solicitations and
contact the relevant National Program Leaders.

**Electronic Subscription to NRI Announcements:**

If you would like to receive notifications of all new announcements
pertaining to the NRI RFA, you can register via Grants.gov at
<http://www.grants.gov/search/subscribeAdvanced.do>.

Enter the e-mail address at which you would like to receive the
announcements

Enter "10.206" for CFDA Number

Select "Subscribe to Mailing List"

Other criteria may be selected; however, your e-mail address and the
CFDA number are the only data required to receive NRI announcements. You
do not need to be a registered user of Grants.gov to use this service.
You may modify your email subscriptions or unsubscribe at any time.

Changes in Strengthening Requirements:

In FY 2007, the NRI implemented changes to eligibility requirements for
Strengthening awards.

Please review Part II, C 2(c) for more details.

TABLE OF CONTENTS

[PART I − FUNDING OPPORTUNITY DESCRIPTION
9](#part-i-funding-opportunity-description)

[A. Legislative Authority and Background
9](#a.-legislative-authority-and-background)

[B. Purpose and Priorities 9](#b.-purpose-and-priorities)

[PART II − AWARD INFORMATION 11](#part-ii-award-information)

[A. Available Funding 11](#a.-available-funding)

[B. Types of Applications 11](#__RefHeading___Toc176921661)

[C. Project Types 12](#c.-project-types)

[D. The NRI and CSREES Strategic Planning
19](#d.-the-nri-and-csrees-strategic-planning)

[E. Program Opportunities 20](#e.-program-opportunities)

[Agricultural Genomics and Biosecurity Cluster Overview
21](#agricultural-genomics-and-biosecurity-cluster-overview)

[20.2 Plant Biosecurity 23](#plant-biosecurity)

[43.0 Animal Genome 25](#animal-genome)

[44.0 Animal Protection and Biosecurity
35](#animal-protection-and-biosecurity)

[51.0 Microbial Genomics 41](#microbial-genomics)

[51.2 Arthropod and Nematode Biology and Management
43](#arthropod-and-nematode-biology-and-management)

[51.8 Microbial Biology 50](#microbial-biology)

[52.1 Plant Genome 53](#plant-genome)

[Agricultural Production and Value-Added Processing Cluster Overview
61](#agricultural-production-and-value-added-processing-cluster-overview)

[41.0 Animal Reproduction 62](#animal-reproduction)

[42.0 Animal Growth and Nutrient Utilization
64](#animal-growth-and-nutrient-utilization)

[56.0 Plant Biology 66](#plant-biology)

[61.0 Agribusiness Markets and Trade
76](#agribusiness-markets-and-trade)

[71.2 Biobased Products and Bioenergy Production Research
77](#biobased-products-and-bioenergy-production-research)

[75.0 Nanoscale Science and Engineering for Agriculture and Food Systems
79](#nanoscale-science-and-engineering-for-agriculture-and-food-systems)

[Nutrition, Food Safety and Quality Cluster Overview
81](#nutrition-food-safety-and-quality-cluster-overview)

[31.0 Bioactive Food Components for Optimal Health
82](#bioactive-food-components-for-optimal-health)

[31.5 Human Nutrition and Obesity 85](#__RefHeading___Toc176921685)

[32.0 Food Safety and Epidemiology 87](#food-safety-and-epidemiology)

[71.1 Improving Food Quality and Value
91](#improving-food-quality-and-value)

[Agroecosystems and Rural Prosperity Cluster Overview
95](#agroecosystems-and-rural-prosperity-cluster-overview)

[23.1 Managed Ecosystems 96](#managed-ecosystems)

[25.0 Soil Processes 99](#soil-processes)

[26.0 Water and Watersheds 101](#water-and-watersheds)

[27.0 Global and Climate Change 102](#global-and-climate-change)

[28.0 Air Quality 103](#air-quality)

[51.9 Biology of Weedy and Invasive Species in Agroecosystems
106](#biology-of-weedy-and-invasive-species-in-agroecosystems)

[62.0 Rural Development 109](#rural-development)

[66.0 Agricultural Prosperity for Small and Medium-Sized Farms
111](#agricultural-prosperity-for-small-and-medium-sized-farms)

[PART III---ELIGIBILITY INFORMATION
113](#part-iiieligibility-information)

[A. Eligible Applicants 113](#a.-eligible-applicants)

[B. Request for Determination 113](#b.-request-for-determination)

[C. Cost Sharing or Matching 113](#c.-cost-sharing-or-matching)

[PART IV---APPLICATION AND SUBMISSION INFORMATION
114](#part-ivapplication-and-submission-information)

[A. Electronic Application Package
114](#a.-electronic-application-package)

[B. Content and Form of Application Submission
115](#b.-content-and-form-of-application-submission)

[C. Submission Dates and Time 134](#c.-submission-dates-and-time)

[D. Funding Restrictions 134](#d.-funding-restrictions)

[E. Other Submission Requirements
134](#e.-other-submission-requirements)

[PART V---APPLICATION REVIEW REQUIREMENTS
136](#part-vapplication-review-requirements)

[A. General 136](#a.-general)

[B. Evaluation Criteria 136](#b.-evaluation-criteria)

[C. Conflicts of Interest and Confidentiality
139](#c.-conflicts-of-interest-and-confidentiality)

[D. Organizational Management Information
139](#d.-organizational-management-information)

[PART VI---AWARD ADMINISTRATION 140](#part-viaward-administration)

[A. General 140](#a.-general-1)

[B. Award Notice 140](#b.-award-notice)

[C. Administrative and National Policy Requirements
140](#c.-administrative-and-national-policy-requirements)

[D. Expected Program Outputs and Reporting Requirements
141](#d.-expected-program-outputs-and-reporting-requirements)

[PART VII---AGENCY CONTACTS 142](#part-viiagency-contacts)

[PART VIII---OTHER INFORMATION 142](#part-viiiother-information)

[A. Access to Review Information 142](#a.-access-to-review-information)

[B. Use of Funds; Changes 142](#b.-use-of-funds-changes)

[C. Confidential Aspects of Applications and Awards
143](#c.-confidential-aspects-of-applications-and-awards)

[D. Regulatory Information 143](#d.-regulatory-information)

[E. Application Disposition 143](#e.-application-disposition)

[F. Materials Available on the Internet
143](#f.-materials-available-on-the-internet)

[G. Electronic Subscription to NRI Announcements
143](#g.-electronic-subscription-to-nri-announcements)

[H. Definitions 144](#h.-definitions)

[TABLE 1. Most Successful Universities and Colleges Receiving Federal
Funds
146](#table-1.-most-successful-universities-and-colleges-receiving-federal-funds)

[TABLE 2. Lowest One Third of Universities and Colleges Receiving
Federal Funds
148](#table-2.-lowest-one-third-of-universities-and-colleges-receiving-federal-funds)

[TABLE 3. Most Successful Universities and Colleges Receiving Federal
and/or NRI Funds
152](#table-3.-most-successful-universities-and-colleges-receiving-federal-andor-nri-funds)

[TABLE 4 NRI Personnel Contact Information
156](#table-4-nri-personnel-contact-information)

[TABLE 5 NRI Program Deadline Date
157](#table-5-nri-program-deadline-date)

[FIGURE 1. Flow Chart for Strengthening Research Award Eligibility
159](#figure-1.-flow-chart-for-strengthening-research-award-eligibility)

[FIGURE 2. Flow Chart for Bridge Grant Eligibility
160](#figure-2.-flow-chart-for-bridge-grant-eligibility)

[NRI Application Checklist 161](#nri-application-checklist)

#   {#section .unnumbered}

# PART I − FUNDING OPPORTUNITY DESCRIPTION 

# 

## A. Legislative Authority and Background 

The authority to support research projects through this program is
contained in 7 U.S.C. 450i(b). Under this authority, subject to the
availability of funds, the Secretary may award competitive research
grants, for periods not to exceed five years, for the support of
research projects to further the programs of the USDA.

In FY 2006, Section 710 of the General Provisions of the Consolidated
Appropriations Act, 2004 (Pub. L. 108-447) provided the Cooperative
State, Research, Education, and Extension Service (CSREES) with the
authority to use up to 22 percent of the amount made available in the
Act for the National Research Initiative program (NRI), to carry out a
competitive grants program under the same terms and conditions as those
provided in Section 401 of the Agricultural Research, Extension, and
Education Reform Act of 1998 (AREERA) (7 U.S.C. 7621). Section 101 of
the Revised Continuing Appropriations Resolution, 2007, (Pub. L. 110-5)
sustained that authority. In FY 2008, CSREES anticipates similar
language; however, funding for integrated projects is contingent on the
inclusion of the integrated authority in the FY 2008 Agricultural
Appropriations Act and the availability of appropriated funds.

Section 401 of AREERA authorizes the Secretary of Agriculture to
establish a research, extension, and education competitive grants
program to address critical emerging U.S. agricultural and rural issues
related to future food production; environmental quality and natural
resource management; farm income; and rural, economic and business, and
community development policy. In addition, the Secretary of
Agriculture is authorized to make grants that address priority mission
areas related to: (1) agricultural genomics, (2) food safety, food
technology, and human nutrition, (3) new and alternative uses and
production of agricultural commodities and products, (4) agricultural
biotechnology, (5) natural resource management, including precision
agriculture, and (6) farm efficiency and profitability, including the
viability and competitiveness of small and medium-sized dairy,
livestock, crop, and other commodity operations.

## B. Purpose and Priorities 

CSREES Competitive Programs Unit administers the NRI. The purpose of the
NRI is to support research grants and integrated research, extension,
and education grants that address key problems of National, regional,
and multi-state importance in sustaining all components of agriculture,
including farming, ranching, forestry (including urban and
agroforestry), aquaculture, rural communities, human nutrition, and
processing. Providing this support requires that NRI advances
fundamental sciences in support of agriculture and coordinates
opportunities to build on these discoveries. This will necessitate new
efforts in education and extension that deliver science-based knowledge
to people, allowing them to make informed practical decisions. Hence,
the NRI is accepting applications for fundamental research,
mission-linked research, and integrated research, extension, and
education projects. However, applicants should know that the NRI will
use no more than 22 percent of available funds to support integrated
projects (see Part I, A) and that these funds will not be distributed
uniformly, but targeted to specific priorities. Targeted priorities for
integrated projects are clearly identified within the detailed
descriptions of program offerings (see Part II, E).

CSREES may also solicit applications for NRI funds through other
announcements, including supplemental FY 2008 NRI RFAs or in conjunction
with multi-agency programs. Such announcements will be made public in
the same manner as this announcement.

**1.** **Fundamental research project**

> Research testing scientific hypotheses and providing basic knowledge
> that enables advances in applied research and from which major
> conceptual breakthroughs are expected to occur.

**2.** **Mission-linked research project**

> Research conducted on specifically identified agricultural problems
> that, through a continuum of efforts, provide information and
> technology that may be transferred to users and may relate to a
> product, practice, or process.

**3. Multidisciplinary project**

> Multidisciplinary projects are research or integrated by nature in
> which investigators from two or more disciplines collaborate closely.
> These collaborations, where appropriate, may integrate the biological,
> physical, chemical, or social sciences.

**4. Integrated projects**

> An integrated project brings together at least two of the three
> components of the agricultural knowledge system (i.e. research,
> education, and extension) around a problem or issue. In FY 2008,
> integrated project proposals must interweave at least two of the three
> components (research, education, and extension) into the project. In
> general, strong integrated projects will be stakeholder driven,
> problem focused, and outcome oriented. They will exhibit a
> collaborative team approach, contain strong plans for project
> management and project evaluation, and produce sustained
> education/extension initiatives.

The programs, described herein, were developed within the context of the
authorized purposes of USDA research, extension, and education and
within the framework of the CSREES Strategic Plan. In addition, the NRI
obtains input from Congress, the National Agricultural Research,
Extension, Education, and Economics Advisory Board, as well as many
university, scientific, and agricultural committees and organizations.
CSREES developed a new stakeholder's Web page
(<http://www.csrees.usda.gov/business/reporting/stakeholder.html>) to
document stakeholder resources that are considered when developing and
updating program descriptions and priorities each year.

# PART II − AWARD INFORMATION 

## 

## A. Available Funding 

There is no commitment by USDA to fund any particular application or to
make a specific number of awards. Contingent on congressional action, in
FY 2008, CSREES anticipates that approximately \$190 million will be
available for support of this program. Of this amount, CSREES
anticipates that no more than 22 percent will be made available to fund
integrated projects (see Part I, A). The remaining funds will be used to
fund research projects. No less than 10 percent of the funds available
to support research projects will be made available for Agricultural
Research Enhancement Awards, excluding New Investigator Awards, and no
more than two percent will be made available for equipment grants.
Further, no less than 30 percent of the funds available for research
projects shall be made available for research to be conducted by
multidisciplinary teams. No less than 40 percent shall be made available
for grants for mission-linked systems research. NRI funds may be used to
fund applications submitted to supplementary NRI RFAs and/or
solicitations for multi-agency programs in which the NRI is
participating.

## B. Types of Applications

In FY 2008, applications may be submitted to the NRI Program as one of
the following four types of requests:

#### 1. New application {#new-application .Style3}

> This is a project application that has not been previously submitted
> to the NRI. All new appropriate applications will be reviewed
> competitively using the selection process and evaluation criteria
> described in Part V.

#### 2. Renewal application {#renewal-application .Style3}

> This is a project application that requests additional funding beyond
> the period that was approved in an original or amended award.
> Applications for renewed funding must contain the same information as
> required for new applications. Additionally, a renewal application
> must contain a Progress Report. Renewal applications must be received
> by the relevant due dates, will be evaluated in competition with other
> pending applications in the appropriate area to which they are
> assigned, and will be reviewed according to the same evaluation
> criteria as new applications, see Part V.

#### 3. Resubmitted application {#resubmitted-application .Style3}

> This is an application that had previously been submitted to the NRI,
> but was not funded. Project Directors (PDs) must respond to the
> previous panel review summary. Resubmitted applications must be
> received by the relevant due dates, will be evaluated in competition
> with other pending applications in the appropriate area to which they
> are assigned, and will be reviewed according to the same evaluation
> criteria as new applications, see Part V. Applications which appear to
> be resubmissions (regardless of the designation) are regarded as such
> by the program and the panel, and compete on the same basis with all
> other applications (new, renewal, and resubmissions) submitted to the
> program at the same time.

#### 4. Resubmitted renewal application {#resubmitted-renewal-application .Style3}

> This is a project application that requests additional funding for a
> project beyond the period that was approved in the original or amended
> award and that had previously been submitted for renewal to the NRI
> Program, but was not approved. The PD must provide a Progress Report
> as required under the Project Description and must respond to the
> previous panel review summary as required under Response to Previous
> Review. Resubmitted renewal applications must be received by the
> relevant due dates, will be evaluated in competition with other
> pending applications in the appropriate areas to which they are
> assigned, and will be reviewed according to the same evaluation
> criteria as new applications, see Part V.

##  

## C. Project Types 

For applications proposing research or integrated research, education,
and extension projects, support will be provided through Standard
Research Grants, Integrated Project Grants, Conference Grants,
Postdoctoral Fellowships, New Investigator Awards, and Strengthening
Awards.

In FY 2008, applications are being solicited for the following project
types:

#### 1. Conventional Projects {#conventional-projects .Style3}

> **(a) Standard Research Grants**
>
> Research will be supported that is **fundamental** or
> **mission-linked** and that is conducted by **individual**
> investigators, co-investigators within the same discipline, or
> **multidisciplinary** teams. Certain programs within the NRI require a
> letter of intent prior to submitting a full application. See specific
> program description to determine whether a letter of intent is
> required.
>
> In 2004, the Coordinated Agricultural Project (CAP) was created to
> support large-scale, multi-million dollar projects to promote
> collaboration, open communication, and the exchange of information;
> reduce duplication of effort; and coordinate activities among
> individuals, institutions, States, and regions. CAP awards are
> [only]{.underline} solicited in defined programs. Project participants
> serve as a team that conducts targeted research in response to
> emerging or priority area(s) of National need. Applications articulate
> how a CAP will complement and/or link with existing programs or
> projects at the National level. A research CAP project contains the
> needed science-based expertise, as well as expertise from principal
> stakeholders and partners to accomplish project goals and objectives.
> Applications should outline the potential of the project, the
> structure, coordination, and plan of implementation, and propose
> several research areas that will be evaluated during the study period.
>
> CAP awards are typically made as continuation grants. A continuation
> grant is a grant instrument by which the Department agrees to support
> a specified level of effort for a predetermined period of time with a
> statement of intention to provide additional support at a future date,
> provided that performance has been satisfactory, appropriations are
> available for this purpose, and continued support would be in the best
> interest of the Federal government and the public.
>
> **(b) Conference Grants**
>
> Scientific meetings that bring together scientists to identify
> research, education, or extension needs, update information, or
> advance an area of science are recognized as integral parts of
> scientific efforts. Support for a limited number of meetings covering
> subject matter encompassed by this solicitation will be considered for
> partial or, if modest, total support. Conference awards are not
> expected to exceed \$10,000 and are not renewable. Indirect costs are
> not allowed. Conference Grant applications should be submitted by the
> deadline date for the appropriate program described under Part II, E.
> Certain programs within the NRI require a letter of intent prior to
> submitting a full application. A letter of intent, however, is not
> required for Conference Grant applications. Applicants interested in
> submitting conference applications are strongly advised to consult the
> appropriate NRI staff before preparing an application.

#### 2. Agricultural Research Enhancement Awards (AREA)  {#agricultural-research-enhancement-awards-area .Style3}

Agricultural Research Enhancement Awards (AREA) strengthen research
capabilities in research programs. These awards are designed to help
institutions develop competitive research programs and to attract new
scientists into careers in high-priority areas of National need in
agriculture, food, and environmental sciences. The AREA program provides
support for Postdoctoral Fellowships, research awards for New
Investigators, and Strengthening Awards. Specific eligibility
requirements for these awards are described below. Applications
submitted by non-United States organizations will not be considered for
support. However, United States citizens applying as individuals for
Postdoctoral Fellowships may do all or part of the proposed work at a
non-United States organization.

> **(a) Postdoctoral Fellowships**
>
> Individuals who have recently received or will soon receive their
> doctoral degree are encouraged to submit an application for a
> Postdoctoral Fellowship. **These applications may be submitted either
> directly by the individual or through the mentor\'s institution. The
> postdoctoral applicant must be the sole PD listed on the
> application**. Certain programs within the NRI require a letter of
> intent prior to submitting a full application. See specific program
> description to determine whether a letter of intent is required.
>
> The following requirements apply for all Postdoctoral Fellowships: 
>
> \(1\) the doctoral degree must be received after January 1, 2005 and
> can not be received later than nine months after the application due
> date for the NRI program of interest;
>
> \(2\) the individual must be a citizen of the United States;
>
> \(3\) the application must contain (A) documentation that arrangements
> have been made with an established investigator to serve as mentor;
> (B) documentation that arrangements have been made for the necessary
> facilities, space, and materials for conduct of the research; and (C)
> documentation from the host institution\'s authorized organizational
> representative (AOR) indicating that the host institution concurs with
> these arrangements; and
>
> \(4\) the research proposed must be solicited in and submitted
> directly to a specific program described under Part II, E.
>
> Although a proposed project may fit in the context of the mentor\'s
> existing research area, the postdoctoral award should initiate an
> independent research program, rather than serve as an extension of
> ongoing projects in the mentor\'s laboratory. Postdoctoral awards are
> limited to a total award of \$125,000 for a two-year duration and are
> not renewable. Funds should be requested primarily for salary support,
> although other expenditures (e.g. supplies, travel, and publication)
> are allowable costs if properly justified. Institutional allowance,
> not to exceed \$2,400/year, may be requested within the \$125,000
> maximum award limit. Indirect costs are not allowed.
>
> An institution may provide compensation for non-research services, but
> such compensation is not considered stipend supplementation. However,
> it is expected that compensated services will occur on a limited,
> part-time basis apart from the normal postdoctoral research
> activities, which require a minimum of 40 hours per week. Under no
> circumstances may the conditions of stipend supplementation or the
> services provided for compensation interfere with, detract from, or
> prolong the fellow\'s two year approved NRI postdoctoral fellowship.
>
> Applications should be submitted to the appropriate research program
> described in this solicitation by the designated deadline for that
> particular program. A separate peer review panel will not be assembled
> to review these applications. Applicants are urged to contact the
> appropriate National Program Leader concerning questions related to
> eligibility, budget, and similar matters.
>
> **(b) New Investigator Awards**
>
> A new investigator is defined as an individual who is beginning
> his/her research career, does not have an extensive research
> publication record, and has less than five years postgraduate,
> career-track research experience. The new investigator may not have
> received competitively awarded Federal research funds with the
> exception of pre- or postdoctoral research awards or USDA NRI Seed
> Grants. The application must contain documentation that lists all
> prior Federal research support. New Investigator award applications
> are subject to letter of intent guidelines. See specific program
> description to determine whether a letter of intent is required.
>
> Applications may be submitted by any State agricultural experiment
> station, college, university, other research institution or
> organization, Federal agency, national laboratory, private
> organization, corporation, or individual. Applications submitted by
> non-United States organizations will not be considered for support.
> The research proposed shall be appropriate to a program described
> under Part II, E and the application must be submitted directly to
> that program by the designated deadline date. A separate peer review
> panel will not be assembled to review these applications.
>
> **(c) Strengthening Awards**
>
> Strengthening Awards consist of Research Career Enhancement Awards
> (Sabbatical Awards), Equipment Grants, Seed Grants, and Strengthening
> Standard Research Awards. **The NRI particularly encourages
> applications for Research Career Enhancement Awards (Sabbatical
> Awards).** All applications submitted for Strengthening Awards must
> fulfill the requirements for a Strengthening Award, as well as be
> appropriate to one of the programs described in this document.
>
> **Flow Chart for Strengthening Award Eligibility**
>
> A flow chart is provided at the end of the document, see Figure 1, for
> determining eligibility for Strengthening Awards.

-   Equipment Grants will be available to PDs at **academic institutions
    not** **among the top 100 universities and colleges for receiving
    Federal funds** **for science and engineering research**, see Table
    1 at the end of the document for a list of the most successful
    institutions. If the institution is listed in Table 1, the Project
    Director is not eligible for an Equipment Grant.

-   Research Career Enhancement Awards, Seed Grants, and Strengthening
    Standard Research Awards will be available to PDs at **small and
    mid-sized academic institutions** (not among the top 100
    universities and colleges for receiving Federal funds for science
    and engineering research) or at an **institution located in an
    Experimental Program for Stimulating Competitive Research (EPSCoR)**
    state. See Table 1 for a list of the most successful institutions.
    If your institution is listed in Table 1 and is not in an EPSCoR
    state, you are not eligible for a Research Career Enhancement Award,
    Seed Grant, or Strengthening Standard Research Award.

> **Strengthening Award Definitions**
>
> **(1) EPSCoR States**
>
> Every three years, the NRI calculates which states are eligible for
> USDA EPSCoR funding. This list is generated by calculating the states
> that have had a funding level from the NRI no higher than the 38^th^
> percentile of all states, based on total funding for the previous
> three-year period (excluding strengthening set-aside funds). For FY
> 2008, the following States meet the requirements for this category:

  ----------- ---------- ---------- ---------- ---------- ---------- ----------
  Alabama     Alaska     Arkansas   Delaware   Hawaii     Idaho      Kentucky

  Louisiana   Maine      Nevada     New Jersey New Mexico North      Oklahoma
                                                          Dakota     

  South       South      Vermont    West       Wyoming               
  Carolina    Dakota                Virginia                         
  ----------- ---------- ---------- ---------- ---------- ---------- ----------

> Other entities eligible for USDA-EPSCoR funds in FY 2008 include the
> following United States commonwealths, territories, possessions and
> their successors, and the District of Columbia:

  ----------------- ---------- ----------------- ------ ----------------- -----------------
  American Samoa    District                     Guam                     Micronesia
                    of                                                    
                    Columbia                                              

  Northern Mariana             Puerto Rico              Virgin Islands of 
  Islands                                               the U.S.          
  ----------------- ---------- ----------------- ------ ----------------- -----------------

> **(2) Small and mid-sized institutions for Research Projects** are
> academic institutions with a current total enrollment of 15,000 or
> less, including graduate and undergraduate and full- and part-time
> students. Applicants applying under this category should indicate the
> current total enrollment of the institution in a cover letter. An
> institution in this instance is an organization that possesses a
> significant degree of autonomy. Significant degree of autonomy is
> defined by being independently accredited as determined by reference
> to the current version of the *Higher Education Directory*, published
> by Higher Education Publications, Inc., 6400 Arlington Boulevard,
> Suite 648, Falls Church, Virginia 22042. (703-532-2300).
>
> **(3) Limited institutional success** is defined as institutions that
> are **not** among the most successful universities and colleges for
> receiving Federal funds for science and engineering research. See
> Table 1 at the end of this document for an alphabetical list of the
> [most]{.underline} successful institutions.
>
> **An individual applicant may submit only one of the following types
> of strengthening applications (research career enhancement, equipment
> grants, and seed grants) as PD or co-PD this fiscal year.**
> Investigators are encouraged to contact the National Program Leader of
> the appropriate program, described in Part II, E, regarding questions
> about suitability of research topics or research topics for which
> equipment would be used to verify allowability.
>
> **[(i) Research Career Enhancement Awards (Sabbatical
> Awards)]{.underline}**
>
> The purpose of these awards is to provide an opportunity for faculty
> to enhance their research capabilities by funding sabbatical leaves.
> These awards will be limited to individual faculty who have
> appointments at small and mid-sized degree-granting institutions that
> previously had limited institutional success and to faculty who have
> appointments at degree-granting institutions eligible for USDA-EPSCoR
> funding. Collaborative arrangements are encouraged. Research
> colleagues who serve as collaborators should not be listed on the
> Senior/Key Person Profile. Awards will be limited to one year of
> salary and funds for travel and supplies. These awards are not
> renewable. Certain programs within the NRI require a letter of intent
> prior to submitting a full application. A letter of intent, however,
> is not required for Research Career Enhancement Award applications.
>
> CSREES also encourages and will support the concept of
> "mini-sabbaticals" for faculty desiring short-term training to learn
> new techniques that will improve their competitiveness. These
> short-term training opportunities generally follow all of the
> sabbatical items described below but for a shorter duration. These
> awards may be used to participate in short courses offered at various
> research institutions.

-   The sabbatical description must include the research interests and
    goals of the PD, the research project to be pursued while on
    sabbatical leave, an indication of how the sabbatical leave will
    enhance the research capabilities of the PD, and a statement of
    future research goals and how the sabbatical will enable the PD to
    pursue these goals.

-   The application should include a letter detailing the particulars of
    the arrangement with the home institution (e.g. dates and duration
    of sabbatical and salary arrangements).

-   The application should also include a letter from the established
    investigator who will be the host. The host's letter should provide
    intent and assurance that all facilities and space necessary to
    conduct the proposed research will be available.

> **[(ii) Equipment Grants]{.underline}**
>
> Equipment grants are designed to strengthen the research capacity of
> institutions. Eligibility for equipment grants is open to any
> degree-granting institution that is not among the most successful
> universities and colleges in receiving Federal funds for science and
> engineering research. See Table 1 for most successful institutions. If
> the institution is listed in Table 1, Project Directors employed by
> the institution are not eligible for Equipment Grants.
>
> These awards are not intended to replace requests for equipment in
> individual research projects. Rather, they are intended to help fund
> items of equipment that will upgrade research infrastructure. Requests
> for computer equipment are allowed only if the equipment is to be used
> in an activity integral to the proposed project. Requests for computer
> equipment will not be permitted if the equipment will primarily serve
> as a word processor or perform administrative functions.
>
> Each request shall be limited to one major piece of equipment within
> the cost range of \$10,000-\$250,000. The amount requested shall not
> exceed 50 percent of the cost or \$50,000, whichever is less. Unless
> waived, it is the responsibility of the PD to secure the required
> matching funds with non-Federal funds. No installation, maintenance,
> warranty, or insurance expenses may be paid from these awards, nor may
> these costs be part of the matching funds. Indirect costs are not
> permitted on Equipment Grant Awards. Certain programs within the NRI
> require a letter of intent prior to submitting a full application. A
> letter of intent, however, is not required for Equipment Grant
> applications. The following requirements apply to all Equipment Grant
> applications.

-   A letter(s) from the organization(s) committed to providing the
    remaining matching non-Federal funds must be included in the
    application.

    -   The application should include a description of the research
        project(s) for which the equipment will be used and detail how
        the equipment will fit into or enhance the research program and
        allow the applicant to become more competitive for future
        funding.

    -   The application should also include a description of similar or
        complementary equipment currently available to the PD and an
        explanation as to why the requested equipment is necessary.

    -   PDs are encouraged to provide evidence of institutional
        commitment for operation and maintenance of requested equipment.
        Arrangements for sharing equipment among faculty are encouraged.
        However, it must be evident that the PD is a principal user of
        the requested equipment.

-   The requirement for matching funds may be waived if three criteria
    are met.

1.  The award is made to a college, university, or research foundation
    maintained by a college or university that ranks in the lowest
    one-third of academic institutions receiving Federal research funds
    (see Table 2 for a list of institutions that are eligible for waiver
    of matching funds for equipment grants);

2.  The equipment to be acquired costs not more than \$25,000; and

3.  The equipment will have either multiple uses within a single
    research project or is useable in more than one research project.

> **[(iii) Seed Grants]{.underline}**
>
> The purpose of these awards is to provide funds to enable
> investigators to collect preliminary data in preparation for applying
> for a Standard Research Grant. The awards are not intended to fund
> stand-alone research projects, but rather projects that will lead to
> further research applicable to one of the research areas in the NRI.
>
> These awards will be limited to faculty with appointments at small and
> mid-sized degree-granting institutions that have had limited
> institutional success and to faculty with appointments at
> degree-granting institutions eligible for USDA-EPSCoR funding. These
> awards will be limited to a total of \$100,000 (including indirect
> costs) for two years and are not renewable*.* Certain programs within
> the NRI require a letter of intent prior to submitting a full
> application. A letter of intent, however, is not required for Seed
> Grant applications. The following requirement applies to all Seed
> Grant applications.

-   Applications for seed grants are expected to indicate how the
    research will enhance future competitiveness of the PD in applying
    for Standard Research Grants from the NRI.

> **[(iv) Strengthening Standard Research Project Awards]{.underline}**
>
> These awards will be limited to faculty with appointments at small and
> mid-sized degree-granting institutions that have had limited
> institutional success and to faculty with appointments at
> degree-granting institutions eligible for USDA-EPSCoR funding. Certain
> programs within the NRI require a letter of intent prior to submitting
> a full application. See specific program description to determine
> whether a letter of intent is required.

#### 3. Integrated Projects  {#integrated-projects .Style3}

> **(a) Integrated Project Grants**
>
> An integrated project, as defined in Part VIII, H, includes two of the
> three components of the agricultural knowledge system (i.e. research,
> education, and/or extension) within a project. The components
> addressed in the project should be interwoven throughout the life of
> the project and act to complement and reinforce one another.

(1) The proposed research component of an integrated project should
    address knowledge gaps that are critical to the development of
    practices and programs to address the stated problem.

(2) The proposed extension component of an integrated project should
    lead to measurable, documented changes in learning, actions, or
    conditions in an identified audience or stakeholder group. Extension
    related activities designed to build institutional capacity are also
    allowable. Extension programs should incorporate a wide range of
    research results, not just those of the current project. Please note
    that research-related activities such as publication of papers, or
    speaking at scientific meetings are not considered extension for the
    purposes of this program.

(3) The proposed education (teaching and teaching-related) component of
    an integrated project should strengthen institutional capacities and
    result in curricula and related products that will be sustained
    beyond the life of the project. The following activities are
    appropriate for the education component of an integrated project:
    curriculum development; instructional materials development;
    education delivery systems; student experiential learning
    (internships, externships, clinics); student recruitment and
    retention efforts; career planning materials and counseling;
    pedagogy; student learning styles and student-centered instruction;
    faculty development programs; student study abroad and international
    research opportunities relevant to overall program goals for U.S.
    agriculture; and faculty and student exchanges.

The bullets below describe additional requirements for integrated
project proposals.

-   Integrated projects should aim to resolve today's problems through
    the application of science-based knowledge;

-   Integrated projects should address needs identified by stakeholders,
    and stakeholder involvement in project development, implementation,
    and evaluation is strongly encouraged, where appropriate;

-   Integrated projects should clearly identify anticipated outcomes and
    must have a plan for evaluating and documenting the success of the
    project. The applicant is strongly advised to consult with an
    evaluation specialist to develop appropriate measures of success;

-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

-   Integrated proposals should contain objectives for each component of
    the project. Please note that extension and education activities are
    expected to differ (see enumerated descriptions above and
    definitions in Part VIII, H) and should be described in separate
    project objectives;

-   Integrated projects must budget sufficient resources to carry out
    the set of extension, research, and/or education activities that
    will lead to the desired outcomes. No more than two-thirds of a
    project's budget may be focused on a single component. In other
    words, no more than two-thirds of the project's budget may be
    allocated to research (or education, or extension);

-   Integrated projects must include individuals on the project team
    with significant expertise in each component of the project
    (research, education, and/or extension);

> Those interested in submitting integrated applications are encouraged
> to contact the appropriate National Program Leader to discuss the
> anticipated project parameters and outcomes to ensure the application
> content appropriately meets the requirements of an integrated project.
>
> See <http://www.csrees.usda.gov/funding/integrated/integrated.html>
> for additional information on integrated programs, including tips for
> writing integrated project proposals and an example of an integrated
> proposal.

**Programs soliciting integrated applications in FY 2008.**

  ----------- ------------------------------------------------------------------------------
  **Program   **Program and Program Element**
  Code**      

  20.2        [Plant Biosecurity[^1]](#_C._Project_Types)

  23.1        [Managed Ecosystems[^2]](#_C._Project_Types)

  28.0        [Air Quality](#air-quality)^2^

  31.0        [Bioactive Food Components for Optimal
              Health](#bioactive-food-components-for-optimal-health)^2^

  31.5        [Human Nutrition and Obesity](#_31.5_Human_Nutrition)^2^

  41.0        [Animal Reproduction](#_C._Project_Types)^2^

  42.0        [Animal Growth and Nutrient
              Utilization](#animal-growth-and-nutrient-utilization)^2^

  43.0        [Animal Genome (A) Translational Animal Genomics](#animal-genome)^2^

  44.0        [Animal Protection and Biosecurity (B): Animal
              Well-Being](#animal-protection-and-biosecurity)^2^

  44.0        [Animal Protection and Biosecurity (C): Animal Biosecurity Coordinated
              Agricultural Project (CAP)](#animal-protection-and-biosecurity) ^1^

  51.2        [Arthropod and Nematode Biology and Management (D): Genes to Practice --
              Protection of Managed Bees Coordinated Agricultural Project
              (CAP)^1^](#_51.2_Arthropod_and)

  51.9        [Biology of Weedy and Invasive Species in
              Agroecosystems^2^](#biology-of-weedy-and-invasive-species-in-agroecosystems)

  52.1        [Plant Genome (D): Applied Plant Genomics Coordinated Agricultural Project
              (CAP)](#_C._Project_Types)^1^

  56.0        [Plant Biology (E): Plant Breeding and Education](#_56.0_Plant_Biology:)^1^

  62.0        [Rural Development](#rural-development)^1^

  66.0        [Agricultural Prosperity of Small and Medium-Sized
              Farms](#_C._Project_Types)^1^

  71.1        [Improving Food Quality and Value](#_C._Project_Types)^2^
  ----------- ------------------------------------------------------------------------------

> A limited number of programs (those with Program Codes 44.0C and
> 52.1D) solicit applications for the Integrated Coordinated
> Agricultural Project (CAP) award. Integrated CAP awards support
> large-scale multi-million dollar projects to promote collaboration,
> open communication, and the exchange of information; reduce
> duplication of effort; and coordinate activities among individuals,
> institutions, States, and regions. Like integrated projects,
> Integrated CAP projects address problems through research, education,
> and extension. Project participants serve as a team that conduct
> targeted research, extension, and education in response to emerging or
> priority area(s) of National need. Applications articulate how an
> Integrated CAP award will complement and/or link with existing
> programs or projects at the National level. An Integrated CAP project
> contains the needed science based expertise in teaching, extension,
> and research, as well as expertise from principal stakeholders and
> partners to accomplish project goals and objectives. Applications
> should outline the potential of the project, the structure,
> coordination, and plan of implementation, and propose several
> research, extension, and education areas that will be addressed during
> the study period. All integrated project requirements described
> earlier in this section apply to integrated CAP projects.

An integrated CAP award is typically made as a continuation grant. A
continuation grant is a grant instrument by which the USDA-CSREES agrees
to support a specified level of effort for a predetermined period of
time, typically one year, with a statement of intention to provide
additional support at a future date, provided that performance has been
satisfactory, appropriations are available for this purpose, and
continued support would be in the best interest of the Federal
government and the public.

> **(b) Bridge Grants**
>
> Bridge grants are a type of integrated award designed to assist small,
> mid-sized, and minority-serving institutions that have not previously
> been successful in obtaining competitive grants under subsection (b)
> of the Competitive, Special, and Facilities Research Grant Act (7
> U.S.C. 450i(b)) (i.e. NRI). Bridge Grants provide funding to sustain
> and enhance important collaborations and activities with the goal of
> leading to future program success or success in obtaining other
> grants. A flow chart for determining applicant eligibility for bridge
> grants is provided at the end of this document in Figure 2.
> Institutions eligible for bridge grants will be considered for up to
> \$100,000 if an integrated project application is considered
> meritorious, but ranks below the funding cutoff during the peer review
> process.
>
> **Applicants may not apply directly for bridge grants.** Bridge grants
> will be awarded only to eligible small- and mid-sized institutions and
> minority-serving institutions (as defined below) which are
> [not]{.underline} among the most successful universities and colleges
> for receiving Federal and/or NRI funds for science and engineering
> research. See Table 3 at the end of this document for an alphabetical
> listing of the most successful institutions. If the institution
> appears in Table 3, Project Directors employed by the institution may
> not be eligible for Bridge Grants. Applicants in this category should
> indicate whether the institution qualifies as a small, mid-sized
> institution or a minority-serving institution (as defined in Part
> VIII, H) and include the documentation requested below.
>
> **(1) Small and mid-sized institutions** for integrated projects are
> defined as academic institutions with a current total enrollment of
> 15,000 or less including graduate, undergraduate, as well as full and
> part-time students. The institutions are not higher than the 50^th^
> percentile of academic institutions funded by the NRI Program in the
> past three years and not within the top 100 Federally-funded
> institutions. See Table 3 at the end of this document for an
> alphabetical listing of the most successful institutions for Federal
> and NRI funding. If the institution appears in Table 3, Project
> Directors employed by the institution are not eligible for Bridge
> Grants.

-   Applicants applying under this category should indicate the current
    total enrollment of the institution in a cover letter. An
    institution in this instance is an organization that possesses a
    significant degree of autonomy. Significant degree of autonomy is
    defined by being independently accredited as determined by reference
    to the current version of the *Higher Education Directory*,
    published by Higher Education Publications, Inc., 6400 Arlington
    Boulevard, Suite 648, Falls Church, Virginia 22042. (703-532-2300).
    Other institutions or organizations involved in small- and mid-sized
    institution eligible projects need not meet the criteria described
    in the definitions for small- and mid-sized institution, but will
    not be eligible for bridge grant funds.

> **(2) Minority-serving institution** is defined as an academic
> institution whose enrollment of a single minority group or a
> combination of minority groups (as defined in Part VIII, H) exceeds 50
> percent of the total enrollment, including graduate and undergraduate
> and full- and part-time students.

-   Applicants applying under this category should indicate the current
    percentage of applicable minority students enrolled at the
    institution in a cover letter. An institution in this instance is an
    organization that possesses a significant degree of autonomy.
    Significant degree of autonomy is defined by being independently
    accredited as determined by reference to the current version of the
    *Higher Education Directory*, published by Higher Education
    Publications, Inc., 6400 Arlington Boulevard, Suite 648, Falls
    Church, Virginia 22042. (703-532-2300). Other institutions or
    organizations involved in minority-serving institution eligible
    projects need not meet the criteria described in the definitions for
    minority-serving institutions, but will be not be eligible for
    bridge grant funds. A list of post-secondary minority-serving
    institutions can be found at
    <http://www.ed.gov/about/offices/list/ocr/edlite-minorityinst.html>.

## D. The NRI and CSREES Strategic Planning

The NRI supports the objectives and goals identified in the CSREES
Strategic Plan
(<http://www.csrees.usda.gov/about/offices/pdfs/csrees_stratic_plan.pdf>).
The CSREES plan has the following goals:

> 1\. [Strategic Goal 1: Enhance International Competitiveness of
> American Agriculture](http://www.ocfo.usda.gov/usdasp/pdf/sp05-03.pdf)
>
> 2\. [Strategic Goal 2: Enhance the Competitiveness and Sustainability
> of Rural Farm
> Economics](http://www.ocfo.usda.gov/usdasp/pdf/sp05-04.pdf)\
> 3. [Strategic Goal 3: Support Increased Economic Opportunities and
> Improved Quality of Life in Rural
> America](http://www.ocfo.usda.gov/usdasp/pdf/sp05-05.pdf)\
> 4. [Strategic Goal 4: Enhance Protection and Safety of the Nation\'s
> Agriculture and Food
> Supply](http://www.ocfo.usda.gov/usdasp/pdf/sp05-06.pdf)\
> 5. [Strategic Goal 5: Improve the Nation\'s Nutrition and
> Health](http://www.ocfo.usda.gov/usdasp/pdf/sp05-07.pdf)\
> 6. [Strategic Goal 6: Protect and Enhance the Nation\'s Natural
> Resource Base and
> Environment](http://www.ocfo.usda.gov/usdasp/pdf/sp05-08.pdf)

The CSREES plan is compatible with the goals of the USDA Strategic Plan
and is a dynamic working document that evolves in response to changes in
National needs. Decisions about NRI priorities are also informed by
stakeholder input, congruence with Presidential initiatives, and reports
from the National Academy of Sciences and National Agricultural
Research, Extension, Education, and Economics Advisory Board (NAREEEAB).
These priorities are further designed to address the purposes of Section
401 of AREERA including all statutorily-identified, critical, emerging
agricultural and rural issues and priority mission areas (See Part I,
A).

## E. Program Opportunities 

CSREES offers a number of programs that support research, education, and
extension, or a combination thereof. CSREES solicits separately for the
Integrated Research, Education, and Extension Program and other programs
that deal with biotechnology risk assessment and higher education. The
programs provide funding for many topic areas related to, but not
duplicated by NRI programs. Applicants are encouraged to examine other
CSREES program descriptions to find the most appropriate source of
funding. Eligibility for these programs is noted in the RFA of a given
program. RFAs can be accessed through the Agency's Web site
(<http://www.csrees.usda.gov/fo/funding.cfm>).

The following program opportunities provide a base from which
applications for Standard Projects, AREA, and Integrated Projects may be
developed. These descriptions provide boundaries on the scope of each
individual program. The NRI encourages submission of innovative
"high-risk" projects with potential for future high impact on
agriculture, as well as innovative applications with potential for
near-term use.

Research projects addressing biological issues should focus on
agriculturally-important organism(s) to accomplish the research
objectives. The use of other organisms as experimental model systems
**MUST** be justified relative to the goals of the appropriate research
program.

**Note to multidisciplinary research teams:** The NRI recognizes the
value of research performed as a team effort and recommends the
following be taken into consideration when assembling a project team and
developing an application for funding. To be competitive, the number of
objectives and the level of personnel involved in the application should
be appropriate to the NRI program and to the activities proposed. A
clear management strategy should be provided which identifies the
contribution of each member of the team.

## Agricultural Genomics and Biosecurity Cluster Overview

The Agricultural Genomics and Biosecurity program cluster primarily
addresses CSREES\' strategic goal to enhance protection and safety of
the Nation\'s agriculture and food supply and to enhance economic
opportunities for agricultural producers. It also supports CSREES\'
strategic goal of protecting and enhancing the Nation\'s natural
resource base and environment.

The Agricultural Genomics and Biosecurity program cluster helps improve
agricultural efficiency and sustainability, lower production costs, and
aid the discovery of new and improved food and forest products for
consumers, as well as alternatives to pesticides and antibiotics to
control disease outbreaks. Crop, forestry, and animal improvements are
supported. Knowledge from this cluster also provides a foundation to
respond to new and re-emerging pathogens or pests of major economic
significance in the U.S. and that threaten both industry viability and
consumer access to safe and affordable food. These programs also
contribute to an agrosecurity program for animals and plants that will
effectively respond to the intentional or accidental entry of a foreign
pathogen, pest, or other biological threat to the United States.
Activities emphasize basic and applied research approaches, as well as
integrated research, education, and extension solutions for identified
priorities.

**[Microbial, Arthropod, or Nematode Sequence Data and Distribution of
Genomic Resources]{.underline}**

Investigators funded by CSREES to work with microbial, arthropod or
nematode genome applications (e.g. genome sequencing, microarrays, etc.)
must include a plan for timely dissemination of information and
deliverables to a clearly identified community of users, as well as to
the scientific community as a whole. In addition to the scientific plan,
applications must include a clear, complete, and workable plan for
sharing results. The plan should be specific about the nature of the
results to be shared, the timing and means of release, constraints on
release, long-term maintenance of data accessibility, and plans for
updating data in response to new information about functional
assignments. If proposing microarray studies, applicants are strongly
encouraged to include a statement addressing Minimum Information About
Microarray Experiment (MIAME) compliance, see
[www.mged.org](http://www.mged.org/). Applications involving the
development of microarrays should include plans for distributing the
arrays as a community resource.

**[Animal or Plant Genome Sequence Data and Distribution of Animal or
Plant Genomic Resources]{.underline}**

Investigators funded by CSREES must make animal and plant genome
sequences, protein sequences, and genomic resources available to all for
use without restriction. Investigators are also encouraged to
collaborate and make information available via the relevant worldwide
Web sites. DNA sequence assemblies of 2kb or greater are to be deposited
in a pre-existing public nucleotide sequence database, such as GenBank:
[www.ncbi.nlm.nih.gov](http://www.ncbi.nlm.nih.gov/), within 24 hours of
generation. Sequence traces from these projects are to be deposited in a
trace archive, such as the National Center for Biotechnology Information
{NCBI} Trace Repository, within one week of production. Sequence traces
from whole genome shotgun projects are to be deposited in a trace
archive, such as NCBI Trace Repository or Ensemble Trace Server, within
one week of production. Whole genome assemblies are to be deposited in a
public nucleotide sequence database as soon as possible after the
assembled sequence has met a set of quality evaluation criteria. Other
nucleotide sequences, such as ESTs, full-length cDNA sequences, etc.,
must be submitted to a pre-existing public nucleotide sequence database,
such as Genbank: [www.ncbi.nlm.nih.gov](http://www.ncbi.nlm.nih.gov/),
according to the currently accepted community standards (Bermuda and Ft.
Lauderdale agreements;
[www.wellcome.ac.uk/assets/wtd003207.pdf](http://www.wellcome.ac.uk/assets/wtd003207.pdf))
following the current guidelines for quality assessment. At a minimum,
these sequences should be deposited within one month of production and
quality assessment. CSREES requires that results of community resource
projects be made immediately available for free and unrestricted use by
the scientific community as soon as the quality of these resources is
verified. CSREES requires that data collection and analysis for
microarray projects comply with the Minimum Information about Microarray
(MIAME; [www.mged.org](http://www.mged.org/)) guidelines. CSREES also
encourages use of the MIAME checklist
([www.mged.org/Workgroups/MIAME/miame_checklist.html](http://www.mged.org/Workgroups/MIAME/miame_checklist.html))
to enable unambiguous interpretation of the data and potential
verification of the conclusions. Data from microarray projects funded by
CSREES must be submitted to a pre-existing public repository for
microarray data, such as Gene Expression Omnibus {GEO}:
[www.ncbi.nlm.nih.gov/geo](http://www.ncbi.nlm.nih.gov/geo), as part of
the process for publishing the experimental results in a peer-reviewed
scientific journal. Data from plant microarrays should also be submitted
to the PLEXdb ([www.plexdb.org/](http://www.plexdb.org/)) to enable
comparative analysis with additional plant gene expression data sets.
Protein sequences generated with CSREES funding must be deposited in a
pre-existing public database, such as the Universal Protein Resource
{UniProt}: [www.uniprot.org](http://www.uniprot.org/), as part of the
process for publishing the experimental results in a peer-reviewed
scientific journal. If the Project Director decides not to publish the
microarray data or protein sequence data generated with CSREES funding,
CSREES requires the Project Director to submit the microarray data to a
pre-existing public repository for microarray data within six months
after performing quality control tests on the data or upon termination
of the CSREES funding, whichever comes first. If CSREES funding produces
additional genomic resources (e.g. libraries, biological reagents,
software, plant genetic stocks, etc.) these should be made available to
the public as soon as their quality is verified according to community
standards. Budgeting and planning for short-term and long-term
distribution of these resources and the timing of release to a clearly
identified community of users, as well as to the scientific community as
a whole should be as described in the original application or in a
revised plan of work prior to funding. When the project involves the use
of proprietary data or materials from other sources, the data or
materials resulting from research supported by this program must be
readily available without any restrictions to the users (no
reach-through rights). The terms of any usage agreements should be
stated clearly in the application or revisions prior to funding. If a
project will use genetic resources from outside the United States, it is
strongly recommended that the Project Director seek information
regarding any required prior informed consent from and benefit-sharing
with the appropriate host country authorities. For further information,
see "Information for U.S. Government Funded Researchers Collecting In
Situ Genetic Resources Outside the United States," housed on the U.S.
Department of State's web site at:
[www.state.gov/g/oes/rls/or/25962.htm](http://www.state.gov/g/oes/rls/or/25962.htm),
or contact the Plant Exchange office, ARS, USDA, at:
[www.ars.usda.gov/Main/docs.htm?docid=7456](http://www.ars.usda.gov/Main/docs.htm?docid=7456),
or contact the National Animal Germplasm Program at:
[www.ars-grin.gov/animal/index.html](http://www.ars-grin.gov/animal/index.html),
as appropriate.

In FY 2008, the NRI invites applications in the following programs
related to Agricultural Genomics and Biosecurity:

> [20.2 Plant Biosecurity]{.underline}
>
> [43.0 Animal Genome]{.underline}
>
> 43.0 Animal Genome (A): Translational Animal Genomics
>
> 43.0 Animal Genome (B): Tools and Resources
>
> 43.0 Animal Genome (C): Bioinformatics
>
> 43.0 Animal Genome (D): Functional Genomics
>
> 43.0 Animal Genome (E): Whole Genome Enabled Selection
>
> [44.0 Animal Protection and Biosecurity]{.underline}
>
> 44.0 Animal Protection and Biosecurity (A): Animal Disease
>
> 44.0 Animal Protection and Biosecurity (B): Animal Well-Being
>
> 44.0 Animal Protection and Biosecurity (C): Animal Biosecurity
> Coordinated Agricultural Project (CAP)
>
> [51.0 Microbial Genomics]{.underline}
>
> 51.0 Microbial Genomics (A): Genome Sequencing
>
> 51.0 Microbial Genomics (B): Functional Genomics of Microorganisms
>
> [51.2 Arthropod and Nematode Biology and Management]{.underline}
>
> 51.2 Arthropod and Nematode Biology and Management (A): Organismal and
> Population Biology
>
> 51.2 Arthropod and Nematode Biology and Management (B): Suborganismal
> Biology
>
> 51.2 Arthropod and Nematode Biology and Management (C): Tools,
> Resources, and Genomics
>
> 51.2 Arthropod and Nematode Biology and Management (D): Protection of
> Managed Bees CAP
>
> [51.8 Microbial Biology]{.underline}
>
> 51.8 Microbial Biology (A): Microbial Observatories
>
> 51.8 Microbial Biology (B): Microbial Associations with Plants
>
> [52.1 Plant Genome]{.underline}
>
> 52.1 Plant Genome (A): Tools, Resources, and Bioinformatics
>
> 52.1 Plant Genome (B): Functional Genomics
>
> 52.1 Plant Genome (C): Genome Structure and Organization
>
> 52.1 Plant Genome (D): Applied Plant Genomics Coordinated Agricultural
> Project (CAP)

## Agricultural Genomics and Biosecurity Program Descriptions

### 20.2 Plant Biosecurity 

[National Program Leaders]{.underline} −

Dr. Liang-Shiou Lin (202-401-5042 or <llin@csrees.usda.gov>)

Dr. John L. Sherwood (202-690-1659 or
[jsherwood@csrees.usda.gov]{.underline})

[Total Program Funds]{.underline} − approximately \$4.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed
    \$1million for project periods of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due March 14, 2008 (5:00 P.M. ET); see
the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M. ET)

**Background**

This program only supports integrated projects aimed at ensuring a
continued supply of safe, high-quality, affordable food and fiber for
consumers in the U.S. and international trade partners. The goal of the
program is to harness our Nation's scientific and technological
resources to help agricultural producers and professionals implement
strategies to safeguard agriculture in the U.S. from critical and
emerging high-consequence plant pathogens and arthropods. To accomplish
this, the program will focus on integrated research, education, and
extension projects that counter threats to the agriculture system in the
U.S., both by stepwise improvements to current responses and by
development of innovative new capabilities.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are: to provide the understanding and
technologies needed to anticipate, deter, protect against, detect,
mitigate, and recover from threats to the Nation's agricultural plant
security; to provide decision makers and responders with knowledge and
decision support tools needed to anticipate, prevent, prepare for, and
respond to agricultural threats of high-consequence plant pathogens and
arthropods; and to enable strategies for control and elimination of
high-consequence plant pathogens and arthropods.

The proposed integrated project must address, by direct investigation of
a high consequence pathogen or arthropod (or with appropriate proxy
species), gaps in knowledge of pathogens and arthropods of high
economic/social impact to the United States. Species of concern to U.S.
plant biosecurity are characterized as emerging, invasive, or
threatening pathogens or arthropods that may be introduced through
intentional or natural pathways and once in the U.S. pose a high risk of
becoming established with significant consequences.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Development of rapid detection/diagnostic procedures that build on
    genomic sequences as available to facilitate monitoring and
    mitigation of plant pathogens and arthropods of high consequence and
    importance. The application must contain a compelling case for the
    proposed work relative to plant biosecurity as outlined in the
    "Background" section of the program description.

```{=html}
<!-- -->
```
1.  2.  Monitoring and mitigation of diseases caused by high consequence
        plant pathogens and arthropods through extension/education
        programs to implement strategies resulting from, or developed in
        conjunction with, etiological and epidemiological
        investigations. The application must contain a compelling case
        for the proposed work relative to plant biosecurity as outlined
        in the "Background" section of the program description.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **March 14, 2008, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

                -   Attach the PDF letter of intent to an email
                    addressed to Dr. Liang-Shiou Lin
                    (<llin@csrees.usda.gov>) [and]{.underline} Dr.
                    John L. Sherwood (<jsherwood@csrees.usda.gov>) with
                    the subject heading '*Letter of Intent Program
                    20.2_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

```{=html}
<!-- -->
```
-   Letters of intent will be reviewed relative to suitability, scope,
    and needs of the program as delineated in the program description
    and priorities.

```{=html}
<!-- -->
```
-   Submission of more than one letter of intent is discouraged.

```{=html}
<!-- -->
```
-   Project Directors will receive a response from the National Program
    Leader inviting or rejecting a full application by **March 28,
    2008**. The National Program Leader will not provide feedback
    regarding content in the letter.

```{=html}
<!-- -->
```
-   Only invited full applications will be reviewed by the panel.

```{=html}
<!-- -->
```
-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

    -   For either priority 1 or 2, the budget should reflect how the
        integration of the research/education/extension activities will
        be achieved.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 43.0 Animal Genome 

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$11 million total

[Proposed Budget Requests]{.underline} − This program contains five
elements. See each program element for additional budgetary information.

Animal Genome (A) Translational Animal Genomics

Animal Genome (B) Tools and Resources

Animal Genome (C) Bioinformatics

Animal Genome (D) Functional Genomics

Animal Genome (E): Whole Genome Enabled Animal Selection

[Letter of Intent]{.underline} − See each program element for additional
details.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

The Animal Genome program provides science-based knowledge and
technologies to generate new or improved high-quality products/processes
and to promote the efficiency of agricultural production systems. This
information will also enhance protection and safety of the Nation's
agriculture and food supply through development and delivery of
information/technologies to genetically improve animals of agricultural
importance. Program success will result in a reduction in the number and
severity of animal disease outbreaks and a decreased dependence on the
widespread use of antibiotics. These program priorities will also
contribute to the protection and enhancement of the Nation's natural
resource base and environment by increasing productivity while
minimizing the environmental consequences.

To meet these identified needs of agriculture, the program's near-term
goals (1-3 years) include using the EST sequence information in dbEST in
an increasing number of ways, particularly as mapping tools and for the
development of gene expression profiling tool. In addition, the program
aims to continue the development and use of micro-arrays to further our
understanding of gene function, develop computational and biological
tools necessary to proceed in the post sequence era, and identify QTL
and ETL for traits of importance to improve livestock production
efficiency and animal health. The mid-term (five year) goals include
developing *in silico* methods that pave the \'virtual path\' leading
from sequence to global function identifying, validating, and fine
mapping of new QTL or ETL for use in genetic improvement and developing
high density SNP marker maps for important livestock species. The
long-term goals (10 years) include using sequence information to
identify new genes, discover and understand regulatory elements, and
study individual genes, their functional products on a molecular level,
and their interactions with other genes or gene networks. Additional
long-term goals include identifying candidate genes for economically
important traits that can be quickly tracked and identified to improve
animal health, product quality, and production efficiency, make these
technologies available to producers, and promote unanticipated
discoveries that have significant impacts on animal agriculture.

[43.0 Animal Genome (A): Translational Animal Genomics]{.underline}

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$450,000
    for a project period of up to 3 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$550,000 for a project period of up to 4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Required for integrated proposals only.
Due March 14, 2008 (5:00 P.M., ET); see the **Other Key Information**
section for format and submission instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

Applications should be developed with Translational goals in mind,
including acceleration of animal breeding, mapping and deployment of
quantitative trait loci (QTLs) and markers in breeding programs, and
molecular identification of beneficial alleles of any particular gene of
agricultural significance. Translational genomics, or \"applied
genomics,\" refers to the investigation of the genome of animals of
agricultural importance and the application of knowledge of the animal
genome to the understanding of more efficient animal production,
superior product quality, and disease prevention. This program element
provides the opportunity to develop new approaches to improve
agriculturally important animals and their products or to aid in disease
prevention. Translational genomics research employs innovative advances
arising from the genome mapping projects and other basic advancements in
animal genomics and applies these advances to the development of
improved animal products. Mapping of the genome is only the first step.
Research is now needed to translate variations in animal genes to
discover the underlying cause for differences in the efficiency of
production, susceptibility or resistance to disease, and improved and/or
healthier products from animals. Although many pieces of the animal's
genetic make-up have been identified, scientists now have the formidable
task of interpreting how they fit together in order to apply the genome
information to improve animal production. Cutting edge translational
genomic research allows investigators to unravel the genetic components
of common and complex traits.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Identification and mapping of genomic markers, including
    quantitative-trait loci (QTL), economic trait loci (ETL), causative
    mutations, and candidate genes for traits of importance to animals
    in agriculture, including aquaculture species.

2.  SNP-based cost-effective genotyping as it relates to whole genome
    enabled animal selection, genomic capabilities that enable
    parentage, and identity verification (traceability) and genetic
    diversity.

3.  Development and application of methods to modify the animal genome
    to aid in the understanding of gene function or expression (e.g.
    RNAi, nuclear transfer, embryonic stem cells, and transgenics).

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Implementation of programs to manipulate and manage the animal's
    genome through the application of new genomic technology. These
    projects are aimed at developing the research needed to fill
    critical knowledge gaps and innovative extension programming
    necessary to enable stakeholders to manipulate and manage the
    animal's genome through the use of molecular markers, including
    quantitative-trait loci (QTL), economic trait loci (ETL), SNPs,
    and/or whole animal genotypes. The results of these research and
    extension projects should be aimed at genetically improving animal
    health, product quality, and/or production efficiency for animals of
    agricultural importance. Projects need to lead to measurable changes
    in the ability of the identified audience or stakeholder group to be
    able to manipulate and manage the animal's genome.

**Other Key Information for Research and Integrated Projects**

-   A letter of intent is required for integrated projects for this
    program element. The letter of intent deadline is **March 14, 2008,
    by 5:00 P.M., Eastern Time**. Please use the formatting guidelines
    below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Peter Burfening (<pburfening@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 43.0A_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **March 28, 2008**. The National Program Leader will not provide
        feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
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```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

-   In the full application, a one-page appendix to the proposal titled
    "Meeting Program Goals" is expected to articulate how their proposal
    meets the near-, mid-, and long-term goals of the Animal Genome
    program. It is not anticipated that any particular proposal will
    meet all of the program goals, but each should meet at least one of
    the near-, mid- and long-term program goals. Attach as a PDF to the
    R&R Other Project Information form in Field 11. Other Attachments.

-   Applications whose primary aim is to improve the efficiency in the
    production of clones or transgenic animals through manipulation of
    the nucleus will no longer be accepted by the Animal Genome program.

```{=html}
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```
-   All model systems, especially the use of laboratory animals, cell
    cultures, etc., must be thoroughly justified in terms of the program
    guidelines and relevance to U.S. animal agriculture. This program
    will no longer accept applications whose studies primarily utilize
    non-agricultural or non-aquacultured species as animal models.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[43.0 Animal Genome (B): Tools and Resources]{.underline}

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$1.5 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$1million
    for a project period of up to 4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program element.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

The Tools and Resources program element will emphasize the development
of basic tools and resources to accelerate research in agricultural
animal genomics. The goal is to develop state-of-the-art tools and
resources that will advance the understanding of animal genomes in terms
of organization and function.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Generation of comparative maps (contig maps and high density linkage
    maps) for use in comparative genomics.

2.  Development of high density SNP maps where these do not already
    exist.

**Other Key Information**

-   Applicants must demonstrate that they can apply the most recent
    technologies to the production of these tools and resources and that
    they will adequately and efficiently store and distribute the tools
    and resources once they are available. A description of quality
    control measures must be included in the application.

1.  

-   Investigators applying under this program element must make a strong
    case that the tools and resources are needed by the community of
    scientists involved and that they do not duplicate resources
    available elsewhere.

-   In a one-page appendix to the proposal titled "Meeting Program
    Goals", PD's are expected to articulate how their proposal meets the
    near-, mid-, and long-term goals of the Animal Genome program. It is
    not anticipated that any particular proposal will meet all of the
    program goals, but each should meet at least one of the near-, mid-,
    and long-term program goals. Attach as a PDF to the R&R Other
    Project Information form in Field 11. Other Attachments.

-   Investigators are encouraged to develop national and international
    collaborations with research groups already working on the species
    of interest to minimize duplication of effort and maximize cost
    effectiveness.

2.  

-   Model systems (especially the use of laboratory animals, cell
    cultures, etc.) will no longer be accepted by the Tools and
    Resources program element.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[43.0 Animal Genome (C): Bioinformatics]{.underline}

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$2.25 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$1.0
    million for a project period of up to four years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this element.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

The Bioinformatics program requests applications for the development of
bioinformatic tools that will assist in functional genomics, annotation
and comparative genomics, *in silico* analysis, and use of genomic data
in genetic improvement programs of agriculturally important animals.
These tools need to be designed to integrate with existing
data/databases (not create new ones), serve as tools for genome
analysis, provide for practical applications of genomic data, and have a
biological framework.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Tools that integrate genome sequence, genome annotations, and
    pedigree information with biological function and phenotypic
    information for a single species or across multiple species.

2.  Animal bioinformatic tools that efficiently and effectively handle
    and interpret the genomic/genetic data being generated to accelerate
    the knowledge discovery process. Examples include technology
    platforms, computational resources, and analytical tools for
    integrative and comparative research.

3.  Development of tools to integrate the use of genomic data (i.e.
    SNPs, haplotypes, and/or whole animal genotypes) into large-scale
    genetic evaluation programs and the use of genomic information to
    design precision mating systems.

**Other Key Information**

-   Investigators applying under this program element must make a strong
    case that the tools are needed by the community of scientists
    involved and that they do not duplicate resources available
    elsewhere.

-   In a one-page appendix to the proposal titled "Meeting Program
    Goals", PD's are expected to articulate how their proposal meets the
    near-, mid-, and long-term goals of the Animal Genome program. It is
    not anticipated that any particular proposal will meet all of the
    program goals but each should meet at least one of the near-, mid-,
    and long-term program goals. Attach as a PDF to the R&R Other
    Project Information form in Field 11. Other Attachments.

-   The research plan must include an exit strategy beyond the requested
    award period, without assuming long-term NRI support.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[43.0 Animal Genome (D): Functional Genomics]{.underline}

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$750,000
    for a project period up to 3 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due March 14, 2008 (5:00 P.M., ET); see
the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

Although progress has been made in understanding the mechanisms that
regulate individual genes in isolated systems, many of the basic
mechanisms that regulate gene expression in the context of the whole
animal still need to be determined. The Functional Genomics program
element aims to assess gene function through development and application
of global (genome-wide or system-wide) experimental approaches. Such
approaches should make use of the information and reagents provided by
genome sequencing and mapping and should employ high-throughput major
innovative technologies for genome-wide analysis supported by
information technology.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Increase the understanding of the biological role of genomic
    sequence, including coding and regulatory sequences, in
    agriculturally important animals and link these sequences to
    biological functions, product quality, or production efficiency.

2.  Increase the understanding of mechanisms that regulate
    agriculturally relevant genes in a systems biology framework.

**Other Key Information**

-   Applications should make creative and innovative use of available
    sequence information and should focus on the function of genes and
    their associate sequence information relative to biological
    function.

```{=html}
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```
-   A letter of intent is required for standard research projects for
    this program element. The letter of intent deadline is **March 14,
    2008, by 5:00 P.M., Eastern Time**. Please use the formatting
    guidelines below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Peter Burfening (<pburfening@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 43.0D_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **March 28, 2008**. The National Program Leader will not provide
        feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
<!-- -->
```
-   In a one-page appendix to the proposal titled "Meeting Program
    Goals", PD's are expected to articulate how their proposal meets the
    near-, mid-, and long-term goals of the Animal Genome program. It is
    not anticipated that any particular proposal will meet all of the
    program goals but each should meet at least one of the near-, mid-,
    and long-term program goals. Attach as a PDF to the R&R Other
    Project Information form in Field 11. Other Attachments.

```{=html}
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```
-   Applications should use tissue or cell-specific high-through-put
    gene expression profiling to identify novel gene products that are
    temporally expressed in these animals. A significant bioinformatics
    component is expected in the application and must be budgeted for
    appropriately. The bioinformatics component of the application must
    include:

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```
-   Data collection protocols;

-   Curation protocols, including quality assessment and quality
    control;

-   Procedures for archiving of data to prevent accidental loss;

-   Protocols and policies related to release of data and submission of
    raw and processed data to public database; and

-   Data warehousing for online-access, including web-interfaces and
    bulk download capability.

```{=html}
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```
-   Collaboration with international partners is appropriate; however,
    applications must be submitted by eligible U.S. institutions.

```{=html}
<!-- -->
```
-   All model systems, especially the use of laboratory animals, cell
    cultures, etc., must be thoroughly justified in terms of the program
    guidelines and relevance to U.S. animal agriculture. This program
    will no longer accept applications whose studies primarily utilize
    non-agricultural or non-aquacultured species as animal models.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[43.0 Animal Genome (E): Whole Genome Enabled Animal
Selection]{.underline}

[National Program Leaders]{.underline} −

Dr. Peter J. Burfening (202-401-5823 or <pburfening@csrees.usda.gov>)

Dr. Muquarrab Qureshi (202-401-4895 or <mqureshi@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.0 million over
five years

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$1.25
    million per year for up to 4 years in duration for a total request
    of \$5.0 million (including indirect costs). It is anticipated that
    one award will be made for this program element.

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due by November 26, 2007 (5:00 P.M.,
ET); see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The Whole Genome Enabled Animal Selection Project element is seeking
applications from a community of researchers to focus on large-scale
application and translation of genome discoveries and technologies for
whole genome animal selection for animals of agricultural importance,
including aquaculture species. The goal of the project is to move animal
genome science from the laboratory to the field to the marketplace and,
in the process, to solve real world problems. To accomplish this goal,
the program is seeking applications that respond to existing or emerging
problems, opportunities, and issues through the development and
application of science-based knowledge to whole genome animal selection.

Applications are expected to demonstrate coherent and complementary
activities with the ultimate goal of being a National strategy or
solution that could be implemented for U.S. agricultural animal
improvement through the application of genome-wide selection to
livestock populations. Applications are expected to take advantage of
recent advances in genomics, including sequenced genomes and high
density SNPs and to translate these basic discoveries and knowledge to
practical applications. Comprehensive approaches are expected to include
coordinated work on several of the following areas, but not limited to:
identification of knowledge gaps and research to close these gaps;
development and implementation of easy-to-use whole genome high
through-put SNP panels; utilization of functional genomic tools,
resources, and knowledge; implementation of bioinformatic-based tools
for data management, selection, and breeding decisions; and effective
communication of whole genome animal selection to end-users, producers,
breeding organizations, livestock producers, scientists, students, and
the lay public.

This project seeks to bring together a multi-institutional and
multi-disciplinary team to integrate genomic discoveries and
technologies with breeding practice and accelerate identification of
traits of interest directly useful to animal breeders. International
collaborations are also encouraged. The project aims to reduce
duplication of efforts and integrate activities among individuals,
institutions, and states. Therefore, applications should clearly
articulate how this award will complement and/or link with existing
programs or projects.

Participants would serve as a team comprised of members working to
conduct research on this emerging genomic area to improve animals
important to U.S. agriculture. This team would contain expertise in
genomics, quantitative genetics and animal breeding, bioinformatics,
animal molecular biology, as well as expertise from principal
stakeholders and partners. Partnerships with end user groups (e.g. breed
associations, breeding organizations, livestock producers, etc.) are a
principal component of this project. The application should outline the
potential of the project team, its structure, coordination, plan of
implementation, and proposed research project will be evaluated during
the project period.

**FY 2008 Priority for Research Projects − Applicants must address the
following priority.**

1.  Whole Genome Enabled Animal Selection Project will focus on the
    application of genome discoveries and technology applied to whole
    genome animal selection for U.S. agriculturally important animal
    improvement. This priority is open to all applicants and is not
    animal species specific.

**Other Key Information**

-   The program anticipates making awards as a continuation grant, which
    is a grant instrument by which the Department agrees to support a
    specified level of effort for a predetermined project period (e.g.
    annually) with a statement of intention to provide additional
    support at a future date provided that performance has been
    satisfactory, appropriations are available for this purpose, and
    continued support would be in the best interest of the Federal
    government and the public.

```{=html}
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```
-   A letter of intent is required for standard research projects for
    this program element. The letter of intent deadline is **November
    26, 2007, by 5:00 P.M., Eastern Time**. Please use the formatting
    guidelines below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director and institutional
                affiliation;

            -   the names of collaborating investigators, institutional
                affiliation; and

            -   the program priority addressed by the project.

        -   On Page 2 include:

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Peter Burfening (<pburfening@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 43.0E_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
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```
-   In a one-page appendix to the proposal titled "Meeting Program
    Goals", PD's are expected to articulate how their proposal meets the
    near-, mid-, and long-term goals of the Animal Genome program. It is
    not anticipated that any particular proposal will meet all of the
    program goals but each should meet at least one of the near-, mid-,
    and long-term program goals. Attach as a PDF to the R&R Other
    Project Information form in Field 11. Other Attachments.

-   An aim of this award is to encourage maximum flexibility in
    translational animal genomics research. Applications will be
    evaluated based on how well their goals and objectives respond to
    current needs utilizing genomic tools and resources. As an award\'s
    comprehensive approach unfolds, unexpected advances and promising
    leads, or unforeseen new National needs related to project goals and
    objectives, may be identified. The project management plan is
    expected to be capable of responding to these opportunities.

-   Invited applications for the Whole Genome Enabled Animal Selection
    Project should include the following information in a single
    project:

    -   A budgeted project management plan to ensure efficient
        functioning of the project team that includes an organizational
        chart, administrative timeline, a description of how the project
        will be governed, identification of short-, medium- and
        long-term metrics to be evaluated, what expectations are
        required from each team member, a mechanism whereby progress
        metrics can be evaluated for future budgetary allocations, and
        how the project will complement and/or link to existing programs
        or projects to include multi-disciplinary, multi-institutional,
        multi-state and international collaborations. The plan must
        include an exit strategy beyond the requested award period,
        without assuming long-term NRI support;

    -   A budgeted data management plan that includes a description of
        how project information, data, and results will be made publicly
        available. The plan must include capacity to freely interface
        with major community databases and with all project locations, a
        description of the database development, deployment,
        nomenclature standardization, data mining and analysis,
        interoperability, web presentation, etc. Applicants must aim to
        release the results of their research to the public in a timely
        manner and in an accessible and usable form. If a professional
        managed community database exists, the plan must demonstrate
        coordination with that database and a letter of support
        submitted with the application. The plan should adapt software
        and data structures already available through an open source
        system, training for all project personnel who will generate or
        analyze data, agreement on nomenclature at every level,
        assurance that the data are compatible with databases or
        information services for long-term curation and storage,
        dedicated personnel to provide day-to-day management of the
        database and compliance monitoring, etc.;

    -   Applications must include an assessment of the present state of
        the genome map, the availability of existing genetic materials
        and technologies, the rationale for choice of the population,
        genotypes or breeding line, and the short and long-term
        applications for animal breeding or other research;

    -   If needed for successful completion of the objectives of this
        research a budgeted plan to develop or improve web accessible
        informatics-based tools for animal breeders that enable
        efficient access to genetic, trait, physical, and expression
        data, etc. The plan may focus on: providing informatics training
        and education opportunities that foster a collaborative
        interface between project participants, computational
        scientists, and end users; the improvement of statistical and
        computational methods for analyzing genome/genetic data critical
        for animal breeding objectives that include controlled
        vocabularies; the improvement of resources for the acquisition,
        management, storage, and interoperability of genome/genetic data
        that can incorporate increasingly diverse information for animal
        improvement;

    -   If needed for successful completion of the objectives of this
        research, a budgeted plan to develop or improve SNP panels
        and/or molecular markers needed to apply whole genome selection
        to U.S. animal breeding objectives and to utilize new genome
        technologies to address problems not readily solved by
        conventional quantitative breeding methods. To prevent
        duplication of effort, applicants are strongly encouraged to use
        the available genetic tools and resources, such as existing
        genomic/genetic maps, SNPs, molecular markers or other existing
        information and technologies to locate, identify and isolate
        traits for selection that are directly useful to breeders;

    -   A budgeted plan for sharing results and management of
        intellectual property that includes a description of what, how,
        and when the user community would have public access to the
        research, education and extension deliverables and outcomes of
        the project; and

    -   A budgeted plan and timeline for an advisory group of principal
        stakeholders and scientists relevant to the proposed research
        projects (e.g. include letters of commitment and rationale for
        their role) to assess and evaluate the quality, potential
        outcomes and impacts, and how they could function effectively to
        support the goals and objectives of the projects.

        -   Applications that do not address at least one of the stated
            research program priorities will be returned without review.

### 44.0 Animal Protection and Biosecurity

National Program Leaders −

Dr. Peter J. Johnson (202-401-1896 or <pjohnson@csrees.usda.gov>)

Dr. Peter R. Brayton (202-401-4399 or <pbrayton@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$15.5 million

[Proposed Budget Requests]{.underline} − This program contains three
elements. See each program element for additional budgetary information.

Animal Protection and Biosecurity (A): Animal Disease

Animal Protection and Biosecurity (B): Animal Well-Being

Animal Protection and Biosecurity (C): Animal Biosecurity Coordinated
Agricultural Project (CAP)

[Letter of Intent]{.underline} − Required for program element (A) Animal
Disease priority 2. See the **Other Key Information** section for format
and submission instructions.

[Application Deadline]{.underline} - December 19, 2007 (5:00 P.M., ET)

**Overview**

This program supports research and integrated projects ranging from
fundamental science to practical application for the protection and
well-being of agriculturally important animal species, including equine
and aquaculture species. The ultimate goal of the program is to
contribute knowledge about agriculturally important animal diseases so
that their severity and economic impacts are eliminated or reduced. In
addition, the program will contribute to knowledge that will improve the
well-being of agriculturally important animals.

[44.0 Animal Protection and Biosecurity (A): Animal Disease]{.underline}

National Program Leaders −

Dr. Peter J. Johnson (202-401-1896 or <pjohnson@csrees.usda.gov>)

Dr. Peter R. Brayton (202-401-4399 or <pbrayton@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$10.0 million

[Proposed Budget Requests]{.underline}

-   Proposed research project budget requests must not exceed \$375,000
    for a project period from 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent Deadline]{.underline} − Due October 9, 2007 (5:00
P.M., ET); **Priority 2 ONLY.** See the **Other Key Information**
section for format and submission instructions.

[Program Deadline]{.underline} -- December 19, 2007 (5:00 P.M., ET)

**Background**

The Animal Disease section of the Animal Protection program focuses on a
select group of high priority diseases of economic importance to U.S.
animal agriculture, including equine and aquaculture species.
Applications will increase knowledge and technology needed to prevent or
reduce the severity of animal diseases. They will also contribute to an
increase in the efficiency of animal production systems, a reduction in
non-tariff trade barriers, and safe guard, high-quality foods for
consumers.

The element addresses a major limiting factor in animal agriculture;
insufficient basic and applied information is currently available about
diseases in animals of agricultural importance. This knowledge gap
impedes our ability to reduce costly economic losses from animal
diseases present in the United States and to prepare for foreign
diseases that may enter accidentally or intentionally. Information gaps
also jeopardize food security and the future viability of animal
industries. Applications should focus on one or more of the following:
pathogen biology; mechanisms of host/pathogen interactions; immunology;
etiology; prevention; control; epidemiology; and ecology.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Species-Specific High Priority Areas **(This priority does NOT
    require a letter of intent).**

    a.  Aquaculture: *Edwardsiella ictaluri*, *Flavobacterium
        psychrophilum*, and *Viral Hemorrhagic Septicemia (VHS)-Great
        Lakes Strain;*

    b.  Equine: Laminitis, *Streptococcus equi* (strangles), and
        *Rhodococcus equi*;

    c.  Poultry: Avian *Clostridium perfringens*, Marek's Disease, and
        Avian pneumovirus;

    d.  Ruminants: Bovine viral diarrhea, Bovine and ovine respiratory
        disease complex, Infectious causes of dairy cattle mastitis, and
        Johne's Disease;

    e.  Swine: Porcine Reproductive and Respiratory Syndrome (PRRS),
        Porcine Circovirus 2, and Swine influenza.; and

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2.  Non-Species-Specific High Priority Areas. **(This priority requires
    a Letter of Intent\
    prior to application submission.** See the **Other Key Information**
    section for format and submission instructions).

    a.  Endemic:

        i.  Diseases that may be introduced to agriculturally important
            animals through interactions with wildlife, including
            Chronic Wasting Disease, with a required emphasis on the
            interface between livestock and the relevant wildlife
            species; Model species are not appropriate (e.g. for Chronic
            Wasting Disease non-cervid models are not appropriate).

        ii. An immunologic approach that seeks to develop a novel
            vaccine or control strategy involving a disease agent other
            than one of the listed species-specific high-priority agents
            if convincing justification is presented that the outcome
            will be broadly applicable to multiple diseases. Also,
            immunology applications that do not include work with a
            specific disease agent provided there is convincing
            justification for broad applicability.

    b.  Foreign or Emerging:

        i.  High consequence, economically relevant Foreign Animal
            Diseases of agricultural species (e.g. Foot and Mouth
            Disease, Avian Influenza, Exotic Newcastle Disease, or
            Classical Swine Fever), as well as high consequence,
            economically relevant Emerging Animal Diseases of
            agricultural species.

**Other Key Information**

-   A letter of intent is required for **Priority 2**. The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Ms.
        Leslie Gilbert (<lgilbert@csrees.usda.gov>) with the subject
        heading '*Letter of Intent Program 44.0A_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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-   Inclusion of power analyses is required if the project uses
    experimental animals.

-   Applications that address Avian Influenza, Johne's Disease, and
    Porcine Reproductive and Respiratory Syndrome (PRRS) remain a high
    priority for funding within the program, which seeks to support and
    strengthen efforts initiated under the Coordinated Agricultural
    Projects (CAPs). Applications on Avian Influenza, Johne's Disease,
    or Porcine Reproductive and Respiratory Syndrome (PRRS) are expected
    to document in the Project Description: (1) how the proposed work
    fits within the framework of the community objectives established
    for the CAPs in the relevant area; (2) that the Project Director is
    not already funded by the CAP for the specific proposed objectives;
    and (3) the Project Director will participate in reporting and
    coordinating activities associated with those projects. Project
    Directors submitting applications on the three diseases who are not
    already affiliated with the projects should consult the websites
    established for these community efforts. Avian Influenza:
    [http://www.aicap.umd.edu](http://www.aicap.umd.edu/);\
    Johne's Disease: [http://www.jdip.org](http://www.jdip.org/); and
    PRRS: [http://www.prrs.org](http://www.prrs.org/).

-   Surveillance as a principal objective is not suitable for this
    program.

-   The program encourages applicants to take advantage of genomic
    approaches (e.g. functional genomics and proteomics) in order to
    accelerate the discovery of new targets for diagnostics, vaccines,
    and treatments. The program supports international efforts to better
    capture the current and future value of microarray data. If
    proposing microarray studies, applicants are required to include a
    statement addressing Minimum Information about Microarray Experiment
    (MIAME) compliance, see:
    [http://www.mged.org](http://www.mged.org/). Applicants must plan to
    release the results of their research to the public in a timely
    manner.

-   Studies of secondary effects or indirect effects of disease (e.g.
    muscle growth) are not suitable for this program.

-   Proposals studying plant-based vaccines for animal diseases are not
    suitable in this program.

-   Applications that develop new or improved diagnostic tests are
    expected to include an appropriate validation plan.

-   Animal genetics applications (i.e. applications with a primary focus
    on identifying, isolating, and characterizing the genetic basis for
    disease resistance in the host animal) should consider submission to
    the Animal Genome program (43.0).

-   Vaccine development applications that may approach or enter the
    commercialization stage are also encouraged to explore the USDA
    Small Business Innovation Research program for possible funding. The
    RFA for that program is available at
    <http://www.csrees.usda.gov/funding/sbir/sbir.html>.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget. Meetings are expected to be held in conjunction
    with the Conference of Research Workers in Animal Disease (CRWAD) in
    early December.

[44.0 Animal Protection and Biosecurity (B): Animal
Well-Being]{.underline}

[National Program Leader]{.underline} − Dr. Peter R. Brayton
(202-401-4399 or <pbrayton@csrees.usda.gov>).

[Total Program Funds]{.underline} − approximately \$1.5 million, with up
to \$1 million for integrated projects

[Proposed Budget Requests]{.underline}

-   Proposed research project budget requests must not exceed \$375, 000
    for a project period of 2--4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$450,000 for a project period of 2--4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} -- Not required for this program element.

[Application Deadline]{.underline} -- December 19, 2007 (5:00 P.M., ET)

**Background**

This element focuses on enhancing animal well-being throughout the food
production cycle by providing information on how animals of agricultural
importance in the U.S. interact with the production environment and
respond to animal management practices. Where appropriate, management
practices will be developed that improve animal well-being. Such
knowledge is needed to remain competitive globally and to maintain
consumer trust through science-based studies. Research to ensure animal
well-being may also help decrease animal management and health-care
costs. This area addresses agricultural food security by helping to
assure continued access of U.S. animal products to National and
international markets.

**FY 2008 Priority for Research Projects − Applicants must address the
following priority.**

1.  Develop science-based criteria to: standardize measurements of
    well-being, including pain, stress, fear, and behavioral needs; and
    assess how each impact animal well-being.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Develop, test, and recommend alternative management practices to
    promote animal well-being and adaptability. Areas of interest
    include housing, handling, transportation, and harvest, for example
    gas stunning/slaughter procedures for food animals.

**Other Key Information for Research Projects**

-   Both basic and applied research applications are solicited that
    contribute to the development of long-term management options and/or
    short-term production practices that assure animal well-being.
    Multi-disciplinary approaches are encouraged.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**Other Key Information for Integrated Projects**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

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-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[44.0 Animal Protection and Biosecurity (C): Animal Biosecurity
Coordinated Agricultural Projects (CAP)]{.underline}

[National Program Leader]{.underline} − Dr. Peter J. Johnson
(202-401-1896 or <pjohnson@csrees.usda.gov>).

[Total Program Funds]{.underline} − approximately \$4.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed \$1.2
    million per year not to exceed four years, providing a total award
    of \$4.8 million (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} -- Not required for this program element.

[Application Deadline]{.underline} -- December 19, 2007 (5:00 P.M., ET)

**Background**

Strengthening the Nation's capacity to protect animal agriculture from
disease losses and threats arising from high impact endemic diseases,
new or re-emerging challenges, or foreign diseases accidentally or
intentionally introduced is a major challenge facing the United States.
The Animal Biosecurity CAP program was initiated in FY 2004 and serves
as a catalyst to bring the larger animal health community together for
specific diseases or issues. The result will better integrate,
coordinate, and complement current and future programs or projects
related to that area beyond those objectives supported by an Animal
Biosecurity award. The program develops and delivers science-based
information and technologies to reduce the number and severity of
agricultural disease outbreaks*.* Studies of zoonotic diseases, such as
Avian Influenza, also benefit public health.

To meet these identified needs of agriculture, the long-term (10-year)
goal for this program is to implement biosecurity protocols on a
national scale for program-identified issues that detect, contain,
minimize, and eliminate the spread of diseases from animal to animal,
site to site, and animal to human (where applicable). This will include
improving the management of program-identified animal diseases that
represent a threat to animal production, biosecurity, and public health.
It will also include major progress towards diminishing the economic
impact of animal diseases, and/or eradicating selected diseases, or
preventing disease introduction into the United States.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  This program [only]{.underline} invites a renewal application for
    the existing Coordinated Agricultural Project (CAP) for Porcine
    Reproductive Respiratory Syndrome (PRRS) Virus.

**Other Key Information**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

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```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

-   This program initiates or maintains CAPs that develop an integrated
    (research, education, and extension) community approach for a
    limited number of program-identified diseases or issues.

    -   Community products such as:

        -   Community roadmaps, including gap analysis;

        -   Standardized protocols for various areas (e.g. diagnostics,
            vaccine trials, animal studies, and genetic resistance
            studies);

        -   Sample repositories and databases, including surveillance
            activities;

        -   Genomics/proteomics tools, reagents, and protocols (e.g.
            mutants, arrays, clone sets, immunological typing of
            animals, bioinformatics tools, and services); or

        -   Extension and communication programs (e.g. training tools,
            demonstrations, conferences, continuing education,
            publications, impact assessment, and websites).

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-   Leveraging and coordinating project resources with other USDA and
    non-USDA efforts for the same area;

-   Filling critical knowledge gaps (e.g. pathogen biology, mechanisms
    of host/pathogen interactions, epidemiology, and effective
    communication protocols) including the exploration of some high-risk
    approaches; the award size is not sufficient to support all needed
    research, some of which is leveraged and supported by other
    programs; and

-   Piloting the implementation of new disease control strategies and
    tools (e.g. vaccines, new or improved diagnostics and detection
    systems, preventatives, and achieve producer outreach programs) for
    the adoption of improved biosecurity measures and awareness.

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-   A PRRS CAP Renewal application should:

    -   Respond to the previous panel summary;

    -   Summarize originally funded research, education, and extension
        project objectives and describe progress to date, including
        milestones achieved for each objective;

    -   Document stakeholder/partner assessment of project impact;

    -   Outline research, education, and extension activities proposed
        for a renewal period, including a discussion of how the proposed
        activities support the Animal Biosecurity program's long-term
        objectives; include a logic model that captures the CAP's
        integrated activities during the next four year period.
        Additional information on logic models can be found at
        <http://www.uwex.edu/ces/pdande/evaluation/evallogicmodel.html>.
        The overall plan should include an approach(es) to measure
        outcomes. CSREES also encourages participation by minority
        serving institutions;

    -   Summarize and assess project management and structure to date,
        including interactions among project participants (e.g. project
        director, co-project directors, collaborators, advisory
        board(s), other relevant partners, and stakeholders); and

    -   Describe proposed changes in project management (if any).

        -   Applications that do not address at least one of the stated
            integrated program priorities will be returned without
            review.

        -   If a competitive renewal is received by the PRRS CAP, the
            program anticipates that a second competitive renewal would
            not be solicited. Instead, the program would initiate a
            focused effort for another high impact disease or issue.
            Therefore, renewal applications should also articulate an
            exit strategy or an alternative self-sustaining strategy
            from continued Animal Biosecurity program support as a
            multi-million dollar CAP.

### 51.0 Microbial Genomics 

[National Program Leader]{.underline} −

Dr. Ann Lichens-Park (202-401-6460 or <apark@csrees.usda.gov>)

Dr. Daniel Jones (202-401-6854 or <djones@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5 million

[Proposed Budget Requests]{.underline} − This program contains two
elements. See each program element for additional budgetary information.

> 51.0 Microbial Genomics (A): Genome Sequencing
>
> 51.0 Microbial Genomics (B): Functional Genomics of Microorganisms

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

The Microbial Genomics program is part of the larger effort at CSREES to
use the understanding of the biological role of gene sequences and gene
expression to address the CSREES strategic goals to enhance economic
opportunities for agricultural producers and to enhance the protection
and safety of the Nation's agriculture and food supply. Investment in
microbial genomics has and will continue to enable improvements in the
quality of agricultural commodities and products and the realization of
more efficient and sustainable production practices. Public investment
in genome sequencing of agriculturally relevant microbial species will
result in improved traits of commodities and more efficient breeding
programs; discovery and utilization of microbes to enhance innate
properties of agriculturally important organisms; improved animal and
plant production and protection; and facilitate better stewardship of
land, air, and water resources.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are to increase the ability to manipulate
microorganisms to benefit U.S. agriculture based on improved
understanding of microbial processes, create faster, more accurate and
cost-effective detection and diagnosis of plant and animal pathogens,
and improve methods of managing plant and animal pathogens and other
agriculturally relevant microbes.

[51.0 Microbial Genomics (A): Genome Sequencing]{.underline}

[National Program Leader]{.underline} −

Dr. Ann Lichens-Park (202-401-6460 or <apark@csrees.usda.gov>)

Dr. Daniel Jones (202-401-6854 or <djones@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$2.5 million for
    project periods for up to 3 years (including indirect costs).

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − This program element is in
partnership with the National Science Foundation (NSF).

Please note that proposals submitted for review in this program element
must be submitted through NSF in accordance with submission instructions
outlined in the separate program solicitation for the FY 2008
NSF/USDA-CSREES Microbial Genome Sequencing program. Visit the program
website (see
<http://www.csrees.usda.gov/fo/microbialgenomesequencingnri.html>) for
detailed application submission and project deadline information.

**Background**

The availability of genome sequences provides the foundation for
understanding how microorganisms function and live, as well as how they
interact with their environments and with other organisms. The sequences
are expected to be available to and used by a community of investigators
to address issues of scientific and societal importance including:

-   Novel aspects of microbial biochemistry, physiology, metabolism,
    development, and cellular biology.

-   The diversity and the roles microorganisms play in complex
    ecosystems and in global geochemical cycles.

-   The impact that microorganisms have on the productivity and
    sustainability of agriculture and natural resources (e.g. forestry,
    soil, and water), as well as on the safety and quality of the
    Nation\'s food supply.

-   The organization and evolution of microbial genomes and the
    mechanisms of transmission, exchange, and reshuffling of genetic
    information.

[51.0 Microbial Genomics (B): Functional Genomics of
Microorganisms]{.underline}

[National Program Leader]{.underline} − Dr. Ann Lichens-Park
(202-401-6460 or <apark@csrees.usda.gov>)

[Total Program Funds]{.underline} − anticipated level of approximately
\$6 million in FY 2009

[Proposed Budget Requests]{.underline} − Not accepting applications for
FY 2008

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − Microbial Genomics (B): Functional
Genomics of Microorganisms will not be offered in FY 2008. This program
is offered in alternate years and it is anticipated that the program
will be accepting applications again in FY 2009.

[]{#_51.2_Arthropod_and .anchor}

### 51.2 Arthropod and Nematode Biology and Management

[National Program Leader]{.underline} − Dr. Mary Purcell-Miramontes
(202-205-0440 or <mpurcell@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$12.9 million

[Proposed Program Funds]{.underline} − This program contains four
elements. See each program element for additional budgetary information.

Arthropod and Nematode Biology and Management (A): Organismal and
Population Biology

> Arthropod and Nematode Biology and Management (B): Suborganismal
> Biology
>
> Arthropod and Nematode Biology and Management (C): Tools, Resources,
> and Genomics
>
> Arthropod and Nematode Biology and Management (D): Protection of
> Managed Bees

[Letter of Intent]{.underline} − See each program element for additional
details.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

The intentional or accidental introduction of arthropod or nematode
pests into the U.S. is a major threat to the security of agricultural
systems, our food supply, and communities. To combat these threats,
conventional agricultural chemicals are the primary means to control
most of these pests, despite concerns about adverse effects on public
health, non-target organisms, and natural resources. Environmentally
safer alternatives have been developed in some systems, such as the use
of biological control organisms (e.g. parasites, predators, and
microbes), semiochemicals, resistant plant varieties, and genetically
modified crops that resist attack by pests. However, fundamental
knowledge of arthropod and nematode biology, which could lead to better
usage of these alternatives or novel approaches to management, is still
lacking in many areas. In addition, growing demands for
organically-grown commodities in the U.S. has led to increased needs for
biologically-based approaches to managing pests. Also, the health of
pollinator populations could be greatly improved if the mechanisms that
affect susceptibility to pests, diseases, disorders, and environmental
stressors were better understood.

To meet these identified needs of agriculture, the long-term (10-year)
goals of this program area are to 1) improve our understanding of the
biotic and abiotic factors associated with establishment and
distribution of pests and beneficial species; and 2) develop the
scientific and technological framework for environmentally sound pest
management strategies. Examples of promising outcomes include
genetically modified arthropods or nematodes for pest control, improved
utilization of biological control organisms, development of novel
pheromone blends or biologically-based pesticides, and adoption of
pest-resistant strains of managed bees.

All four program elements in the Arthropod and Nematode Biology and
Management program area support research in the following systems:
Horticultural and field crops, forests, rangelands, urban landscapes,
livestock, and food or feed transported and stored for human
consumption. Pest organisms are limited to insects, mites, ticks,
plant-parasitic nematodes, and weeds in the context of a biological
control agent. Beneficial species include biological control organisms
(e.g. insects, microbes, or nematodes) of the above pests and
pollinators. Arthropods, which vector plant or livestock diseases
important to agriculture, are also appropriate.

[51.2 Arthropod and Nematode Biology and Management (A): Organismal and
Population Biology]{.underline}

[National Program Leader]{.underline} − Dr. Mary Purcell-Miramontes
(202-205-0440 or <mpurcell@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.3 million

[Proposed Program Funds]{.underline} −

-   Proposed research budget requests must not exceed \$350,000 for
    single-investigator projects and \$450,000 for multi-institutional
    or multidisciplinary projects for project periods of 2-4 years
    (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − November 26, 2007 (5:00 P.M., ET); see
the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} -- February 14, 2008 (5:00 P.M., ET)

**Background**

The Organismal and Population Biology element of the Arthropod and
Nematode Biology and Management program will support fundamental and
applied research at the organismal and population level to address the
challenges of managing arthropod or nematode pests and enhancing use of
beneficial organisms.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Determine chemical-ecological or eco-physiological mechanisms that
    affect abundance of pests or beneficial species.

2.  Characterize population genetic processes that affect establishment
    and/or movement of pests or beneficial species.

3.  Elucidate multitrophic interactions between pests, beneficial
    organisms, or microbes and commodities (e.g. plants or livestock).

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 26, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Mary Purcell-Miramontes **(**<mpurcell@csrees.usda.gov>**)**
        with the subject heading\
        '*Letter of Intent Program 51.2A_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
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```
-   The Project Description portion of the application must include a
    section providing a clear justification for the system studied, in
    terms of economic and/or societal benefit to agriculture and rural
    communities. Studies of model systems may be submitted to the
    program only if knowledge gained is applied to systems of economic
    or societal importance within the submitted project.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[51.2 Arthropod and Nematode Biology and Management (B): Suborganismal
Biology]{.underline}

[National Program Leader]{.underline} − Dr. Mary Purcell-Miramontes
(202-205-0440 or <mpurcell@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3.1 million

[Proposed Program Funds]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project periods of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due March 14, 2008 (5:00 P.M., ET); see
the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

The Suborganismal Biology element of the Arthropod and Nematode Biology
and Management program supports fundamental and applied research at the
cellular and molecular levels to address the problem of managing
arthropod and nematode pests and the Nation's over-dependence on harmful
pesticide applications. Advances in the molecular genetics, physiology,
biochemistry, and genomics of arthropods and nematodes are poised to
provide novel solutions to these problems that threaten the Nation's
food supply and natural resources.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Characterization of digestive physiology, endocrine,
    neurophysiological, or biochemical processes of arthropods and
    nematodes.

2.  Understanding the cellular, biochemical, and molecular level
    interactions of arthropods or nematodes with associated organisms
    (e.g. host plants, livestock, microbes, or beneficial organisms).

3.  Elucidation of the mechanism of action of novel targets for pest
    control, including semiochemicals and fundamental pesticide
    resistance studies.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **March 14, 2008, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Mary Purcell-Miramontes **(**<mpurcell@csrees.usda.gov>**)**
        with the subject heading\
        '*Letter of Intent Program 51.2B_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **March 28, 2008**. The National Program Leader will not provide
        feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
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```
-   The Project Description portion of the application must include a
    section providing a clear justification for the system studied, in
    terms of economic and/or societal benefit to agriculture and rural
    communities. Studies of model systems may be submitted to the
    program only if knowledge gained is applied to systems of economic
    or societal importance within the submitted project.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[51.2 Arthropod and Nematode Biology and Management (C): Tools,
Resources, and Genomics]{.underline}

[National Program Leader]{.underline} − Dr. Mary Purcell-Miramontes
(202-205-0440 or <mpurcell@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3.5 million

[Proposed Program Funds]{.underline} −

-   Proposed research project budget requests must not exceed \$750,000
    for project periods of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − March 14, 2008 (5:00 P.M., ET); see the
**Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

The Tools, Resources, and Genomics element of the Arthropod and Nematode
Biology and Management program will support research to better develop
genomic resources, tool development, and fundamental knowledge about the
functions of genes for arthropods and nematodes of agricultural
importance.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Develop innovative approaches for mapping, identification,
    sequencing, and/or expression of genes to enable future studies on
    genome organization and lead to hypothesis testing research.

2.  Generate bioinformatic tools to manage and interpret sequence data
    (e.g. analytical tools for integrative and comparative genomics),
    technology platforms, and computational resources.

3.  Characterize, on a large scale, the function(s) of genes or networks
    of genes.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **March 14, 2008, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Mary Purcell-Miramontes **(**<mpurcell@csrees.usda.gov>**)**
        with the subject heading\
        '*Letter of Intent Program 51.2C_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **March 28, 2008**. The National Program Leader will not provide
        feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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```
-   We encourage submission of proposals for organisms with extensive
    genomic information (e.g. ESTs and physical maps).

-   The Project Description portion of the application must include a
    section providing a clear justification for the system studied, in
    terms of economic and/or societal benefit to agriculture and rural
    communities. Studies of model systems may be submitted to the
    program only if knowledge gained is applied to systems of economic
    or societal importance within the submitted project.

```{=html}
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```
-   The outcome of all draft sequencing projects is expected to include
    generation of high quality sequence data, organization of sequence
    reads into contiguous sequences (contigs), correlation with physical
    maps when appropriate, annotation of open reading frames, and
    deposition of information in a publicly accessible database.

-   Investigators are encouraged to seek support from other sources so
    that complete sequence data can be obtained in a reasonable time
    frame. If parallel support from another agency is under
    consideration or being planned, investigators should indicate in the
    proposal how the funded activity will be organized and coordinated
    within the larger project.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[51.2 Arthropod and Nematode Biology and Management (D): Protection of
Managed Bees Coordinated Agricultural Project (CAP)]{.underline}

[National Program Leader]{.underline} − Dr. Mary Purcell-Miramontes
(202-205-0440 or <mpurcell@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4 million

[Proposed Program Funds]{.underline} −

-   Proposed integrated project budget requests must not exceed \$1
    million per year, not to exceed 4 years, providing a total award of
    \$4.0 million (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − November 26, 2007 (5:00 P.M., ET); see
the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

Coordinated Agricultural Project (CAP) proposals will be solicited for a
community of researchers, extension specialists and/or educators
focusing on an existing or emerging issue of national importance on the
biology and management of arthropods or nematodes, and which is poised
to lead to practical management solutions for pests or beneficial
species.

Due to the award size, only 1 proposal is likely to be funded for a 4
year period. The program anticipates making awards as a continuation
grant, which is a grant instrument by which the Department agrees to
support a specified level of effort for a predetermined project period
(e.g. annually). Additional support will be made at a future date.
Provided that performance has been satisfactory, appropriations are
available for this purpose, and continued support is in the best
interest of the Federal government and the public. Solicitation for new
CAP proposals on this topic is not anticipated the following year.

In FY 2008, the issue will focus on the decline of managed bee
pollinators. Bee pollination is responsible for \$15 billion in added
crop value, particularly for specialty crops, such as almonds and other
nuts, berries, fruits, and vegetables. Bee populations throughout the
U.S. are in serious decline due to pests, diseases, and environmental
stresses, including pesticide exposure, inadequate nutritional
resources, and extreme temperatures. In addition, a potentially new
phenomenon, tentatively termed Colony Collapse Disorder, is threatening
the honey bee industry and potentially may impact the Nation's food
supply. It has become increasingly difficult for beekeepers to meet the
pollination demand for several crops and the cost of bees used for
pollination services has more than doubled. The recent completion of the
honey bee genome and whole genome microarray may allow researchers to
develop effective strategies to better protect managed bees and to
improve the viability of the apiculture industry. A coordinated approach
that links basic and applied research, in conjunction with extension and
educational activities to better protect and manage bee pollinators is
encouraged.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Improve the health of managed bee populations in agricultural
    systems. Submitted proposals should include at least two of the
    following activities:

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```
a.  Research that could be applied to future extension and/or
    educational programs. Research is expected to be multidisciplinary,
    addressing genomics, breeding, pathology, immunology, and/or applied
    ecology that elucidates the interaction of population declines of
    managed bees with biotic and abiotic factors (e.g. pests, diseases,
    disorders, environmental stressors, or current management
    practices).

b.  Extension programs that develop and implement novel management
    strategies for protection of managed bees.

> c\. Educational programs that develop innovative curricula on the
> intersection of ecology and genomics with student experiential
> learning elements to facilitate practical application of knowledge.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 26, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Mary Purcell-Miramontes **(**<mpurcell@csrees.usda.gov>**)**
        with the subject heading\
        '*Letter of Intent Program 51.2D_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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```
-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
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```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
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```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
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```
-   Applications that do not address the stated integrated program
    priority will be returned without review.

```{=html}
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```
-   Applicants are strongly encouraged to see the previously funded CAP
    awards for guidance\
    (e.g. <http://www.aicap.umd.edu/>; <http://www.prrs.org/>;
    <http://maswheat.ucdavis.edu/>;
    http://www.uark.edu/ua/ricecap/[)]{.underline}

-   Flexibility in attainment of project goals is an important feature
    of CAP projects. It is recognized that unexpected advances and
    promising leads, or unforeseen needs related to project goals and
    objectives, may emerge during the project. As a result, objectives
    may be revised and/or new objectives may be developed with
    associated budget adjustments. In addition, the program does not
    expect that all investigators associated with the proposed project
    will be supported throughout its duration. It is suggested that
    investigators involved in shorter-term, specific tasks be supported
    through a series of renewable subcontracts.

-   CAP projects should include an advisory board of principal
    stakeholders and partners (to aid in evaluation of scientific merit,
    agricultural relevance, and progress). The advisory board will also
    serve to identify the most promising objectives and work plans to
    pursue in the coming year (for which sub-contracts and plans of work
    would subsequently be submitted for approval from the Authorized
    Departmental Officer).

```{=html}
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```
-   The lead project director is expected to make a significant time
    commitment to assure that the project remains his or her top
    priority. To support the lead project director, as well as other
    project personnel, applicants are encouraged to include additional
    administrative support in the budget request.

-   A project management plan should be included to ensure efficient
    functioning of the CAP team. The plan should include an
    organizational chart, administrative timeline, a description of how
    the project will be governed, and identification of short-, medium-
    and long-term metrics to be evaluated, roles and responsibilities of
    team members, a mechanism whereby progress metrics can be evaluated
    for future budgetary allocations, and how the project will
    complement and/or link to existing programs or projects. The plan
    must include an exit strategy beyond the requested award period,
    without assuming long-term NRI support

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```
-   For projects with an educational objective, an integral part of the
    project should be a broadening educational experience for students,
    postdoctoral research associates and others to participate in the
    CAP. The plan must include examples of measurable outcomes (e.g.
    development of integrative university-level teaching
    modules/curricula utilizing the knowledge for the problem area).
    Also, the plan should include approaches to evaluate educational
    deliverables (e.g. curricula design; exceptional expertise
    development). We also encourage coordination with the CSREES
    educational programs to partner with minority serving institutions.
    The following link has been included to access CSREES educational
    funding opportunities,
    <http://www.csrees.usda.gov/about/offices/serd_funding.html>;

```{=html}
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```
-   The CAP program must develop publicly accessible products such as
    (but not limited to):

    -   Standardized protocols for various areas (e.g. diagnostics for
        pest or pathogen detection, resistance, or breeding studies);

    -   Sample repositories and databases;

    -   Genomics/proteomics tools, reagents, and protocols (e.g. arrays,
        clone sets, bioinformatics tools, and services); or

    -   Extension and communication programs (e.g. training tools,
        demonstrations, conferences, continuing education, publications,
        impact assessment, and Web sites).

```{=html}
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```
-   Leveraging and coordinating project resources with other USDA and
    non-USDA efforts for the same area;

-   Filling critical knowledge gaps including the exploration of some
    high-risk approaches

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```
-   If a project is funded, beginning in the first year of funding,
    project directors are required to organize annual meetings for the
    CAP group. Reasonable travel expenses should be included as part of
    the project budget.

### 51.8 Microbial Biology 

[National Program Leaders]{.underline} −

Dr. John L. Sherwood (202-690-1659 or <jsherwood@csrees.usda.gov>)

Dr. Ann Lichens-Park (202-401-6460 or <apark@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$7.4 million

[Proposed Budget Restrictions]{.underline} − This program contains two
elements. See each program element for additional budgetary information.

Microbial Biology (A): Microbial Observatories

Microbial Biology (B): Microbial Associations with Plants

[Letter of Intent]{.underline} − See each program element for additional
details.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

Microorganisms have a tremendous impact on the productivity and
profitability of U.S. agriculture. Microorganisms associated with plants
and animals may increase productivity, cause or help prevent disease,
and/or affect the safety and quality of the Nation's food supply. New
microbes and microbial communities are routinely being discovered and
characterized as genomic and metagenomic tools become readily available
to the research community. The pattern and distribution of microbes can
have a tremendous effect on the environment. Understanding both the
interaction of individual microbes with their host and how communities
of microbes become established, communicate, and prosper are essential
to elucidate the mechanisms by which microbes impact agricultural
production.

This program enhances the protection and safety of the Nation's
agriculture and food supply. More specifically, through science-based
knowledge and education, information and technologies are developed and
delivered that reduce the incidence of food-borne illnesses and
contaminants and reduce the number and severity of agricultural pest and
disease outbreaks. Understanding the nature of microbes and their
communities will assure sustainable agricultural production systems to
provide food, fiber, and biofuels for tomorrow. Additionally, aspects of
these programs also enhance economic opportunities for agricultural
producers and protect the Nation's natural resource base and
environment.

[51.8 Microbial Biology (A): Microbial Observatories]{.underline}

[National Program Leaders]{.underline} − Dr. John L. Sherwood
(202-690-1659 or <jsherwood@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$2.0 million will be
provided by USDA-CSREES

[Proposed Budget Restrictions]{.underline} −

-   Proposed awards are expected to range between \$500,000 and
    \$2,000,000 for project periods from 2-4 years (including indirect
    costs).

[Letter of Intent]{.underline} − Not required for this program element.

[Application Deadline]{.underline} − This program element is in
partnership with the National Science Foundation (NSF).

Please note that proposals submitted for review in this program element
must be submitted through NSF in accordance with submission instructions
outlined in the separate program solicitation for the FY 2008
NSF/USDA-CSREES Microbial Observatories program.

**Background**

Microorganisms are critical to the productivity and sustainability of
agricultural ecosystems. They can be detrimental (e.g. by causing
disease) or beneficial (e.g. by reducing the incidence of disease or by
contributing to nutrient cycling). Methods of managing agricultural
systems can significantly impact microbial community composition and
functioning. Very little is currently known about the extent and
significance of such impacts.

CSREES, in partnership with the National Science Foundation, has
announced an expanded competitive grants program on Microbial
Observatories. This program will now support research to discover and
characterize novel microorganisms and microbial communities and to study
their roles in agriculturally relevant environments. Additional
information regarding this program has been released as a separate
program announcement. Please visit:
[www.csrees.usda.gov/fo/fundview.cfm?fonum=1460](http://www.csrees.usda.gov/fo/fundview.cfm?fonum=1460)
.

[51.8 Microbial Biology (B): Microbial Associations with
Plants]{.underline}

[National Program Leaders]{.underline} − Dr. Ann Lichens-Park
(202-401-6460 or <apark@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.4 million

[Proposed Budget Restrictions]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project periods of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due October 9, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

Unlocking the information in microbial genomes is essential to
understanding the molecular mechanisms underlying agriculturally
relevant processes in microbes and managing microorganisms for the
benefit of U.S. agriculture. These processes include pathogenicity,
disease suppression by biological control agents, and mechanisms of
microbial communication. This program supports fundamental
hypothesis-driven research on the interactions between microorganisms
and plants with which they are associated. The program encourages
application of knowledge gained to systems of economic importance to
U.S. agriculture or of importance to agricultural sustainability.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are: improved resistance to high-impact plant
diseases based on knowledge of plant pathogens, their plant hosts, and
host-pathogen interactions; improved methods of manipulating
plant-associated microorganisms to develop more effective,
environmentally sound, profitable, and safer disease management
practices by interfering with microbial cell to cell signaling; and
improved understanding of how pathogens spread within a plant.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Elucidation of molecular mechanisms of disease and resistance
    interactions between microbial plant pathogens and their host
    plants. This priority area will accept research applications that
    focus only on the microorganism, as well as applications that focus
    on the association between the microorganism and the plant.
    Applications that address plant defense or plant disease resistance
    genes without a significant focus on the microorganism are not
    appropriate for this program element, but may be appropriate for the
    Plant Biology (A): Gene Function and Regulation program.

2.  Molecular mechanisms of communication among plant-associated
    microorganisms (e.g. plant pathogens, microbial biological control
    agents, and nitrogen-fixing bacterial endosymbionts) and their plant
    hosts. Within communities of microorganisms, there are communication
    and interaction among the same and different species of microbes.
    Microbes are also communicating with the plants within and on which
    they live. This priority area includes communication associated with
    microbial quorum sensing, as well as signaling between plants and
    their associated microbial communities.

3.  Mechanisms by which pathogens spread over short distances, within a
    plant host or between neighboring plants. Pathogens studied under
    this priority area can be either plant pathogens or human food
    safety pathogens.

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```
1.  

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr. Ann
        Lichens-Park (<apark@csrees.usda.gov>) with the subject heading\
        '*Letter of Intent Program 51.8B_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel

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-   Applications must address microbial associations with plants using
    microorganisms and/or plants that are economically important or that
    are important to agricultural sustainability (e.g. microorganisms
    that contribute to more environmentally sustainable crop
    production). In the "Rationale and Significance" section of the
    project description, applicants are required to include a subsection
    entitled "Justification of Relevance to U.S. Agriculture" providing
    a clear justification for the system studied in terms of economic
    and/or societal benefit to U.S. agriculture.

-   Studies of model systems may be submitted to the program only if
    knowledge gained is applied to systems of economic or societal
    importance to U.S. agriculture within the experimental design of the
    submitted project and to be implemented during the project period.
    If the application focuses significantly on the plant side of the
    association in addition to the microbes, knowledge gained from a
    model plant must be applied to a plant of economic importance to
    U.S. agriculture or to agricultural sustainability.

-   Applications that focus on how microbial processes affect the soil
    environment should consider submission to the Soil Processes program
    (25.0).

-   Applicants proposing to study long-distance spread of plant
    pathogens of significant consequence should consider submission to
    the Plant Biosecurity program (20.2).

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 52.1 Plant Genome 

[National Program Leader]{.underline} − Dr. Ed Kaleikau (202-401-1931 or
<ekaleikau@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$10.0 million, with
up to \$5.0 million for integrated projects.

[Proposed Budget Requests]{.underline} − This program contains four
elements. See each program element for additional budgetary information.

Plant Genome (A): Tools, Resources, and Bioinformatics

Plant Genome (B): Functional Genomics

Plant Genome (C): Genome Structure and Organization

Plant Genome (D): Applied Plant Genomics Coordinated Agricultural
Project (CAP)

[Letter of Intent]{.underline} − Required for Plant Genome (D): Applied
Plant Genomics Coordinated Agricultural Project (CAP).

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Overview**

This program supports research and integrated projects ranging from
technology development to fundamental science and practical application
for crop or forestry improvement in the United States. The ultimate goal
of the program is to contribute knowledge about the biology of
agriculturally important plant processes and traits, which can be used
to develop plants with enhanced economic value and expanded utilities.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program include increased fundamental knowledge of the
structure, function and organization of plant genomes to improve
agricultural efficiency and sustainability; effective integration of
modern molecular breeding technologies and classical breeding practice
for U.S. crop and forestry improvement; and improved U.S. varieties for
agricultural growers and producers.

In FY 2008, the program will continue to focus on agriculturally
significant plant families or species. The program elements Plant Genome
(A): Tools, Resources, and Bioinformatics and (B): Functional Genomics
are focused on agriculturally important specialty crops in Rosaceae
(e.g. apple, cherry, peach, strawberry, etc.) and Compositae (e.g.
lettuce, sunflower, etc.). Plant Genome (C): Genome Structure and
Organization will focus on wheat (*Triticum aestivum*); and Plant Genome
(D): Applied Plant Genomics CAP is open to all applicants and is NOT
plant species specific.

Next year, in FY 2009, the program anticipates focusing on the
agriculturally important crops or reference model species in Poaceae
(e.g. rice, wheat, barley, maize, sorghum, etc.) and/or Fabaceae (e.g.
soybean, peanut, alfalfa, Phaseolus, *Medicago truncatula,* etc.).

[52.1 Plant Genome (A): Tools, Resources, and
Bioinformatics]{.underline}

[National Program Leader]{.underline} − Dr. Ed Kaleikau (202-401-1931 or
<ekaleikau@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$2.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$400,000 for
    project periods of 2-3 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program element.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The Plant Genome (A): Tools, Resources, and Bioinformatics program
element will focus on research to advance knowledge of the genome in
agriculturally significant specialty crops in Rosaceae (e.g. apple,
cherry, peach, strawberry, etc.) and Compositae (e.g. lettuce,
sunflower, etc.) for U.S. agriculture. The development and transfer of
genome-wide high-throughput technologies can lead to improved quality of
human nutrition, health and well-being, enhanced economic opportunities,
and protection of the environment.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Use of genome-wide high-throughput approaches for mapping and
    identification of important genes (e.g. Physical maps, ESTs, cDNAs,
    BAC libraries, SNPs, FISH, micro-arrays, transformation
    technologies, etc.) including MAS and QTL analysis (e.g. biotic and
    abiotic tolerance, quality, yield, growth habit, root morphology,
    branching, seed dormancy, heterosis, male sterility, fertility
    restoration, flowering time, seed shattering, self-incompatibility,
    etc.) and comparative genomics (e.g. enabling cross-species markers,
    etc.). These tools and resources can be developed with fundamental
    or applied goals in mind, including but not limited to mapping and
    deployment of beneficial QTL in classical breeding programs and
    molecular identification of beneficial alleles of any particular
    gene of agricultural significance.

2.  Plant bioinformatics to enable genome-wide high-throughput
    cross-species comparisons and to link genomic data to agronomic and
    quality traits of economic value in agricultural plants.

**Other Key Information**

-   Applicants must justify the potential impact of the proposed
    research and demonstrate that they can apply the most recent
    technologies. If tools and resources are developed (e.g. biological
    materials, germplasm, software, etc.), an applicant must budget for
    and demonstrate an adequate and efficient storage and distribution
    of the tools and resources once they are available. A description of
    quality control measures must be included in the application.

-   Applicants must include a budgeted plan for the release of the
    results of their research to the public in a timely manner. All
    sequence and expression data must be released to public repositories
    (e.g. Genbank under the Bermuda standards; GEO under MIAME
    compliance; etc.). All phenotype and map data must be deposited into
    an appropriate public database (e.g. major community databases,
    etc.) in a rapid timeframe after quality control tests. Arrangements
    must be documented in the application.

-   Applicants are encouraged to develop National and international
    collaborations with research groups already working on the species
    of interest to minimize duplication of effort and maximize cost
    effectiveness. U.S. collaboration with international partners is
    appropriate; however, applications must be submitted by eligible
    U.S. institutions.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[52.1 Plant Genome (B): Functional Genomics]{.underline}

[National Program Leader]{.underline} − Dr. Ed Kaleikau (202-401-1931 or
<ekaleikau@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$2.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$400,000 for
    project periods of 2-3 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program element.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The Plant Genome (B): Functional Genomics program element will focus on
assessing gene function through development and application of
genome-wide high-throughput experimental approaches in agriculturally
significant specialty crops in Rosaceae (e.g. peach, apple, strawberry,
cherry, etc.) and Compositae (e.g. lettuce, sunflower, etc.) for U.S.
agriculture.

**FY 2008 Priority for Research Projects − Applicants must address the
following priority.**

1.  Increase the understanding of the biological role of genomic
    sequence, including coding, regulatory and repeated sequences, and
    to link these sequences to physiological functions or agricultural
    and food processes.

**Other Key Information**

-   Applicants must justify the potential impact of the proposed
    research. If tools and resources are developed (e.g. biological
    materials, germplasm, software, etc.), an applicant must budget for
    and demonstrate an adequate and efficient storage and distribution
    of the tools and resources once they are available. A description of
    quality control measures must be included in the application.

-   Applicants must include a budgeted plan for the release of the
    results of their research to the public in a timely manner. All
    sequence and expression data must be released to public repositories
    (e.g. Genbank under the Bermuda standards; GEO under MIAME
    compliance; etc.). All phenotype and map data must be deposited into
    an appropriate public database (e.g. major community databases,
    etc.) in a rapid timeframe after quality control tests. Arrangements
    must be documented in the application.

-   Applicants are encouraged to develop National and international
    collaborations with research groups already working on the species
    of interest to minimize duplication of effort and maximize cost
    effectiveness. U.S. collaboration with international partners is
    appropriate; however, applications must be submitted by eligible
    U.S. institutions.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[52.1 Plant Genome (C): Genome Structure and Organization]{.underline}

[National Program Leader]{.underline} − Dr. Ed Kaleikau (202-401-1931 or
<ekaleikau@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$1.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$1million for
    project periods of 2-3 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program element.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The Plant Genome (C): Genome Structure and Organization program element
will focus on research to advance knowledge of the genome of wheat
(*Triticum aestivum*) as an international effort
(<http://www.wheatgenome.org/>) and in coordination with other U.S.
Federal Agencies and currently funded projects.

**FY 2008 Priority for Research Projects − Applicants must address the
following priority.**

1.  Develop or improve the physical map of the genome of hexaploid wheat
    (*Triticum aestivum*) as a prerequisite for genome sequencing or
    other basic and applied research.

**Other Key Information**

-   Applicants must justify the potential impact of the proposed
    research. If tools and resources are developed (e.g. biological
    materials, germplasm, software, etc.), an applicant must budget for
    and demonstrate an adequate and efficient storage and distribution
    of the tools and resources once they are available. A description of
    quality control measures must be included in the application.

-   Applicants must include a budgeted plan for the release of the
    results of their research to the public in a timely manner. All
    sequence and expression data must be released to public repositories
    (e.g. Genbank under the Bermuda standards; GEO under MIAME
    compliance; etc.). All phenotype and map data must be deposited into
    an appropriate public database (e.g. major community databases,
    etc.) in a rapid timeframe after quality control tests. Arrangements
    must be documented in the application.

-   Applicants are encouraged to develop National and international
    collaborations with research groups already working on the species
    of interest to minimize duplication of effort and maximize cost
    effectiveness. U.S. collaboration with international partners is
    appropriate; however, applications must be submitted by eligible
    U.S. institutions.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[52.1 Plant Genome (D): Applied Plant Genomics Coordinated Agricultural
Project (CAP)]{.underline}

[National Program Leader]{.underline} − Dr. Ed Kaleikau (202-401-1931 or
<ekaleikau@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed a
    cumulative \$5 million for a four year period (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 26, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The applied plant genomics Coordinated Agricultural Project (CAP)
element is seeking applications for a community of researchers,
educators, and extension specialists to focus on large-scale application
and translation of genome discoveries and technology for U.S. crop or
forestry improvement. The goal of the CAP is to move science from the
lab to the field to the marketplace and, in the process, to solve real
world problems. To accomplish this goal, the program is seeking
applications that respond to existing or emerging problems,
opportunities, and issues through the development and application of
science-based knowledge.

CAP applications are expected to demonstrate coherent and complementary
integrated activities with the ultimate goal of being a National
strategy or solution that could be implemented for U.S. agricultural
crops or forestry improvement. Applications are expected to take
advantage of recent advances in genomics and to translate basic
discoveries and knowledge to practical applications. Comprehensive
approaches are expected to include coordinated work on several of the
following areas but not limited to: development and implementation of
easy-to-use molecular markers for breeding; establishment of mapping
populations; utilization of functional genomic tools, resources, and
knowledge; identification of genomic intervals carrying genetic traits
of interest (e.g. yield, quality, and disease) and pest resistance,
stress tolerance, bioenergy, etc.; implementation of informatics-based
tools for breeding; development and use of extension tools to provide
appropriate audiences with information on agricultural advances and
challenges; and educate future generations of agricultural scientists in
technology use and transfer.

A CAP should seek to bring together a multi-state, multi-institutional,
and multi-disciplinary team to integrate genomic discoveries and
technology with breeding practice; accelerate identification of traits
of interest directly useful to breeders to develop improved varieties;
develop related education and degree program training for students and
emerging scientists in the practical application of genomics-based
tools; and provide complementary extension efforts to bring
science-based information to relevant audiences that will allow them to
make informed decisions. The intent of the CAP is to promote
collaboration, open communication, the exchange of information and the
development of resources that accelerate application of genome discovery
and technology to plant improvement. The CAP aims to reduce duplication
of efforts and integrate activities among individuals, institutions,
states, and regions. Therefore, applications should clearly articulate
how a CAP award will complement and/or link with existing programs or
projects.

CAP participants would serve as a team comprised of members working in
discovery, learning, and engagement to conduct research, education, and
extension utilizing an integrative approach on an emerging or priority
area to improve plants important to U.S. agriculture. This integrated
team would contain expertise in genomics, genetics, breeding, genetic
resources, bioinformatics, plant biology, extension education, program
evaluation, agricultural education, curriculum development, economics,
sociology, and human sciences, as appropriate, as well as expertise from
principal stakeholders and partners. Partnerships with end user groups
(e.g. industry, processors, growers, etc.) are strongly encouraged. The
application should outline the potential of the CAP team, its structure,
coordination and plan of implementation, as well as propose an
integrated research, education, and extension project that will be
evaluated during the project period.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Improvements in U.S. crop and forestry production through the
    application and translation of knowledge generated via genome-wide
    discoveries and high-throughput technologies for traditional
    breeding practice. This priority is open to all applicants and is
    NOT plant species specific.  Submitted proposals should include the
    following activities:

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a.  Extension programs to deliver timely, sound and objective
    translation of genomic, genetic and breeding information directly
    useful to U.S. growers and producers to make informed decisions and
    adopt new technologies that result in measurable changes in
    practice.

b.  Education programs to develop graduate curriculums in modern
    molecular breeding technologies, including the use of genomic tools
    to train the next generation of plant breeders and strengthen U.S.
    plant breeding capacity.

c.  Research programs to fill knowledge gaps and adopt new genomic
    technologies that significantly reduce the breeding cycle time and
    cost of phenotypic evaluations for improvements in U.S. crop or
    forestry production.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 26, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to three pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 and 3 include

            -   a descriptive title; and

            -   a brief statement of **integrated** approaches and
                objectives

    -   Attach the PDF letter of intent to an email addressed to Dr. Ed
        Kaleikau (202-401-1931 or <ekaleikau@csrees.usda.gov>) with the
        subject heading\
        '*Letter of Intent Program 52.1D_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is not permitted.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

-   Support will be provided as a Coordinated Agricultural Project (CAP)
    award that will not exceed a total budget (including indirect costs)
    of \$5 million (\$1.25 million per year) for a period of time not to
    exceed 4 years. The program anticipates making awards as a
    continuation grant, which is a grant instrument by which the
    Department agrees to support a specified level of effort for a
    predetermined project period (e.g. annually) with a statement of
    intention to provide additional support at a future date, provided
    that performance has been satisfactory, appropriations are available
    for this purpose, and continued support would be in the best
    interest of the Federal government and the public.

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-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

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-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

-   Applicants are encouraged to see the previously funded CAP awards
    for guidance (e.g. <http://www.aicap.umd.edu/>;
    <http://www.prrs.org/>; <http://maswheat.ucdavis.edu/>;
    <http://www.uark.edu/ua/ricecap/>[).]{.underline} Projects may not
    reflect this current FY CAP program description that has evolved
    from earlier descriptions.

-   Applicants are encouraged to develop National and international
    collaborations with research groups already working on the species
    of interest to minimize duplication of effort and maximize cost
    effectiveness. U.S. collaboration with international partners is
    appropriate; however, applications must be submitted by eligible
    U.S. institutions.

-   An aim of a CAP award is to encourage maximum flexibility in applied
    plant genomics research, education and extension. Applications will
    be evaluated based on how well their goals and objectives respond to
    current needs utilizing genomic tools and resources. It is
    recognized however, that as an award\'s comprehensive approach
    unfolds, unexpected advances and promising leads, or unforeseen new
    National needs related to project goals and objectives, may be
    identified. The CAP team members are expected to be capable of
    responding to these opportunities. As a result, there is an
    expectation that objectives may be redirected and/or new objectives
    may be developed with associated budget adjustments. To encourage
    flexibility, the program does not expect that all investigators
    associated with the proposed project will be supported throughout
    its duration. It is suggested that investigators involved in
    shorter-term, specific tasks be supported through a series of
    renewable subcontracts. In their original budgets, applicants may
    request that no more than 25 percent of the requested funds be
    available to accomplish time-critical objectives of National
    interest that they will determine at a later date. The requested
    funds should be indicated on\
    Field H, Other Direct Costs, of the budget form and identified as
    \"Future National Interests\" in the budget narrative.

-   In a Single Integrated Research, Education, and Extension
    Application, applied plant genomic projects are requested that
    incorporate the following:

> \(a\) A budgeted plan and timeline for extension initiatives leading
> to measurable behavior change or adoption of technology in an
> identified audience or stakeholder group. Collaboration with Extension
> personnel is encouraged to transform developed plant genomics
> information into eXtension Communities of Practice
> [http://about.extension.org/university-researcher/](http://about.extension.org/)
> where appropriate;
>
> \(b\) A budgeted plan and timeline for education (teaching)
> initiatives must include approaches to evaluate educational
> deliverables (e.g. curricula design and exceptional core competencies
> in plant genomics) for expertise development through undergraduate and
> graduate training. As an integral part of the project approach, a
> broadening educational experience for students (e.g. provide
> innovative frameworks for curriculum development); undergraduate and
> graduate training; and/or exceptional learning opportunities in
> emerging knowledge areas, postdoctoral research associates and others,
> to participate in the CAP. The plan must include education (e.g.
> development of integrative university-level teaching modules/curricula
> utilizing the knowledge for the problem area) opportunities with
> measurable outcomes for groups under-represented in science to
> participate. We also strongly encourage coordination with the CSREES
> educational programs as an opportunity, for example, to partner with
> minority serving institutions. The following link has been included to
> access CSREES educational funding opportunities,
> <http://www.csrees.usda.gov/about/offices/serd_funding.html>;
>
> \(c\) A budgeted project management plan and timeline to ensure
> efficient functioning of the CAP team that includes an organizational
> chart, administrative timeline, a description of how the project will
> be governed, and identification of short-, medium- and long-term
> metrics to be evaluated, what expectations are required from each team
> member, a mechanism whereby progress metrics can be evaluated for
> future budgetary allocations, and how the project will complement
> and/or link to existing programs or projects to include
> multi-disciplinary, multi-institutional, multi-state and international
> collaborations. The plan must include an exit strategy beyond the
> requested award period, without assuming long-term NRI support. The
> management of the research, education, and extension integrative
> activities must be clearly incorporated in the overall management
> plan;
>
> \(d\) A budgeted data management plan and timeline that includes a
> description of how project information, data, and results will be made
> publicly available (e.g. capacity to freely interface with major
> community databases and with all project locations), a description of
> the database development, deployment, nomenclature standardization,
> data mining and analysis, interoperability, web presentation, etc.
> Applicants must aim to release the results of their research to the
> public in a timely manner and in an accessible and usable form. If a
> professional managed community database exists, the plan must
> demonstrate coordination to that database and a letter of support
> submitted with the application. To the extent possible, the plan
> should adapt software and data structures already available through an
> open source system, adopt a LIMS convention for the project with
> breeder input into the ontogeny and design of the system, training for
> key project personnel who will generate or analyze data, agreement on
> nomenclature at every level, assurance that the data are compatible
> with databases or information services for long-term curation and
> storage, dedicated personnel to provide day-to-day management of the
> database and compliance monitoring, etc.;
>
> \(e\) A budgeted plan and timeline to develop or improve
> high-throughput mapping and marker development, establish mapping
> populations, and identify genomic intervals carrying traits of
> agronomic interest directly useful to breeders and to other biologists
> for fundamental plant science research. The plan may include
> production of localized or total-genome maps that will be useful in
> improvement or in cloning genes of agricultural importance. The
> application should clearly justify the nature of the map to be
> constructed (e.g. genetic, physical, or comparative); high density or
> low density. Applications must include an assessment of the present
> state of the genome map, the availability of existing genetic
> materials and technologies, the rationale for choice of the mapping
> population, genotype or breeding line, and the short- and long-term
> applications of the map for plant breeding or other research;
>
> \(f\) A budgeted plan and timeline to develop or improve web
> accessible informatics-based tools for plant breeders that enable
> efficient access to genetic, trait, physical, and expression data,
> etc. The plan may focus on to the extent possible: providing
> informatics training and education opportunities that foster a
> collaborative interface between CAP participants, breeders,
> biologists, computational scientists, and end users; the improvement
> of statistical and computational methods for analyzing genome/genetic
> data critical for plant breeding objectives that include controlled
> vocabularies; the improvement of resources for the acquisition,
> management, storage, and interoperability of genome/genetic data that
> can incorporate increasingly diverse information for plant
> improvement; the enhancement of tools for analysis of plant genome
> sequence data including quantitative and graphical representation of
> germplasm relatedness, comparison of data across species, and QTL
> analysis; and the improvement of resource Web pages for specific
> classes of traits, proteins, genes, or metabolic pathways for plant
> improvement, etc.;
>
> \(g\) A budgeted plan and timeline to develop or improve molecular
> markers and apply marker-assisted breeding/selection to U.S. plant
> breeding objectives and to utilize new genome technologies to address
> problems not readily solved by conventional breeding methods. The CAP
> will support projects to locate, identify, and isolate genes that are
> important to the productivity and sustainability of U.S. agriculture.
> To prevent duplication of effort, applicants are strongly encouraged
> to use the available genetic tools and resources, such as existing
> genomic/genetic maps, cytogenetic stocks, alien addition lines, near
> isogenic lines, mutants, transposons, molecular markers, or other
> existing information and technologies to locate, identify, and isolate
> genes that are directly useful to breeders;
>
> \(h\) A budgeted plan and timeline for sharing results and management
> of intellectual property that includes a description of what, how, and
> when the user community would have public access to the research,
> education, and extension deliverables and outcomes of the project; and
>
> \(i\) A budgeted plan and timeline for an integrated advisory group of
> principal stakeholders and scientists relevant to the proposed
> research, education, and extension projects (e.g. include letters of
> commitment and rationale for their role) to assess and evaluate the
> quality, potential outcomes, and impacts, and how they could function
> effectively to support the goals and objectives of the CAP.

-   Applications that do not address at least one of the stated
    integrated program priorities will be returned without review.

## Agricultural Production and Value-Added Processing Cluster Overview

The Agricultural Production and Value-Added Processing program cluster
addresses CSREES' strategic goals to enhance competitiveness and
sustainability of rural and farm economies and to enhance international
competitiveness of American agriculture. The programs in this cluster
also generate knowledge that will assist CSREES' strategic goals to
support increased economic opportunities and improved quality of life in
rural America; enhance protection and safety of the Nation's agriculture
and food supply; improve the Nation's nutrition and health; and protect
and enhance the Nation's natural resource base and environment.

Agricultural production and marketing play a crucial role in the success
and growth of the Nation's economy. The programs in the Agricultural
Production and Value-Added Processing program cluster support
fundamental and mission-linked research and integrated projects to
address current and future challenges to food, feed, and fiber
production, post-harvest processing, and competitiveness of U.S.
agricultural in domestic and international markets. The programs also
support the science-based knowledge and technology development that will
lead to new and improved uses for agricultural and forestry biomass in
bioenergy and industrial applications. Research supported by
Agricultural Production programs forms the scientific knowledge base
needed to use the increasing amounts of genomics data, tools, and
resources for food, feed, fiber, and fuel production. Projects supported
by the programs apply cutting edge technologies and tools, such as
nanotechnology, genomics, proteomics, and metabolic engineering, to
ensure that agricultural production in the U.S. remains competitive,
innovative, and sustainable.

Programs in this cluster range from fundamental research on plant and
animal biology to applied research on product development, improvement,
and agricultural markets and trade, thus linking basic research to
application, policy, and practice. Education and extension projects will
enable transfer of knowledge from researchers to producers, consumers,
industry, and other stakeholders. Projects supported by these programs
will provide vital science-based knowledge, education, and extension to
ensure future growth and development of agricultural production and\
value-added processes, as well as competitiveness of U.S. agriculture.
The knowledge, education, and extension will, in turn, increase economic
opportunities for agricultural producers and provide agricultural
products with enhanced value and lower cost for consumers.

In FY 2008, the NRI invites applications in the following programs
related to Agricultural Production and Value-Added Processing:

> [41.0 Animal Reproduction]{.underline}
>
> [42.0 Animal Growth and Nutrient Utilization]{.underline}
>
> [56.0 Plant Biology]{.underline}
>
> 56.0 Plant Biology (A): Gene Function and Regulation
>
> 56.0 Plant Biology (B): Environmental Stress
>
> 56.0 Plant Biology (C): Biochemistry
>
> 56.0 Plant Biology (D): Growth and Development
>
> 56.0 Plant Biology (E): Plant Breeding and Education
>
> [61.0 Agribusiness Markets and Trade]{.underline}
>
> [71.2 Biobased Products and Bioenergy Production Research]{.underline}
>
> [75.0 Nanoscale Science and Engineering for Agriculture and Food
> Systems]{.underline}

##  {#section-4 .Style-Heading-2-+-10-pt-Not-Italic-Black}

## Agricultural Production and Value-Added Processing Program Descriptions

### 41.0 Animal Reproduction

[National Program Leader]{.underline} − Dr. Mark Mirando (202-401-4336
or <mmirando@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.5 million, with up
to \$900,000 for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$350,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$450,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − November 15, 2007 (5:00 P.M., ET)

**Background**

Reducing infertility and improving fertility in breeding populations of
agriculturally important animals, including aquacultured species, is of
major importance for efficient animal production. In several species,
fertility has declined significantly over the past several decades. New
knowledge is needed to improve fertility and facilitate implementation
of integrated animal production systems that will contribute to
sustainability of the animal production unit. Approaches to managing
animal reproduction also are key to future application of
biotechnologies. Therefore, the objective of this program is to increase
the knowledge base for reproductive biology of agriculturally important
animals with the goal of reducing infertility and improving overall
reproductive management in animal production systems.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are to improve fertility and decrease
infertility; develop improved methods for sterilization and production
of monosex populations of animals; and improve reconstitution of
germplasm from preserved sources, including cryopreserved gametes and
embryos.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Gonadal function, including production, function, and preservation
    of gametes.

2.  The hypothalamic-pituitary axis.

3.  Embryonic and fetal development, including interaction between the
    conceptus and its uterine environment.

**Other Key Information for Research Projects**

-   All model systems, especially the use of laboratory animals, cell
    cultures, etc., must be thoroughly justified in terms of the program
    guidelines and relevance to U.S. animal agriculture. This program no
    longer accepts applications whose studies primarily utilize
    non-agricultural or non-aquacultured species as animal models.

-   Applications that focus on uterine defense mechanisms (e.g.
    non-disease specific immunology) should be submitted to the Animal
    Protection and Biosecurity program (44.0). Applications addressing
    the effects of disease, animal health, or alterations in the immune
    system on reproduction should not be submitted to this program.
    Applications that involve transcriptional profiling or sequencing of
    genes involved in reproduction must include physiological or
    functional studies at the cellular, systemic, or whole animal level.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Development, delivery, and implementation of approaches or
    management practices to regulate fertility through manipulation or
    management of gonadal function, the hypothalamic-pituitary axis,
    and/or embryonic and fetal development.

#### Other Key Information for Integrated Projects {#other-key-information-for-integrated-projects .Style1}

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
<!-- -->
```
-   Applications that focus on uterine defense mechanisms, e.g.,
    non-disease specific immunology, should be submitted to the Animal
    Protection and Biosecurity program (44.0). Applications addressing
    the effects of disease, animal health, or alterations in the immune
    system on reproduction should not be submitted to this program.
    Applications that involve transcriptional profiling or sequencing of
    genes involved in reproduction must include physiological or
    functional studies at the cellular, systemic, or whole animal level.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 42.0 Animal Growth and Nutrient Utilization

[National Program Leader]{.underline} − Dr. Mark Mirando (202-401-4336
or <mmirando@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.5 million, with up
to \$900,000 for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$350,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$450,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

Suboptimal nutrition and growth are limiting factors in animal
productivity. New information regarding these processes in
agriculturally important animals, including aquaculture and aquacultured
species, is lacking. The primary objective of the program is to increase
our understanding of the biological mechanisms underlying animal growth,
development of skeletal muscle, lactation, and nutrient digestion and
metabolism. New knowledge for contemporary and future agricultural
systems is needed to improve animal production and control muscling,
growth, metabolism, and mammary function. Novel research is also needed
to identify biological mechanisms for improving dietary nutrient
availability, directing nutrient partitioning toward more protein and
less fat, and minimizing excretion of nutrients as waste products.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are to improve quality and efficiency of meat,
milk, and egg production; improve animal utilization of nutrients; and
reduce output of nutrients into the environment as animal waste
products.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Improve quality and efficiency of meat, milk, and egg production.

2.  Control of nutrient intake, digestion, absorption, and availability
    to improve nutrient utilization and minimize excretion of nutrients
    as waste products.

**Other Key Information for Research Projects**

-   All model systems, especially the use of laboratory animals, cell
    cultures, etc., must be thoroughly justified in terms of the program
    guidelines and relevance to U.S. animal agriculture. This program
    will no longer accept applications whose studies primarily utilize
    non-agricultural or non-aquacultured species as animal models.

-   Applications that involve transcriptional profiling or sequencing of
    genes involved in animal growth, lactation, or nutrient utilization
    must also include physiological or functional studies at the
    cellular, systemic, or whole-animal level.

-   Applications concerning the developmental biology or nutritional
    regulation of the immune system should be submitted to the Animal
    Protection and Biosecurity (44.0A): Animal Disease program element.
    Applications addressing developmental biology of the reproductive
    system, including embryonic, gonadal, and placental development, and
    applications dealing with nutritional regulation of reproduction,
    should be submitted to the Animal Reproduction program (41.0).
    Applications focusing on the effects of diseases or alterations in
    the immune system on animal growth, lactation or nutrient
    utilization, or those that emphasize nutritional regulation of
    animal health or immune function, should not be submitted to this
    program. Applications seeking to create functional foods (e.g. to
    increase the amount of omega-3 fatty acids, conjugated linoleic
    acids, or nutritional components in meat, milk, or eggs) should not
    be submitted to this program.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Application and translation of knowledge, discoveries, and
    technologies in animal growth to improve quality and efficiency of
    meat, milk, and egg production, thereby improving animal production
    and increasing beneficial contributions to the environment.

2.  Application and translation of knowledge, discoveries, and
    technologies in animal nutrient utilization to control nutrient
    intake, digestion, absorption, and availability, thereby improving
    animal production and increasing beneficial contributions to the
    environment.

**Other Key Information for Integrated Projects**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

-   Applications that involve transcriptional profiling or sequencing of
    genes involved in animal growth, lactation, or nutrient utilization
    must also include physiological or functional studies at the
    cellular, systemic, or whole-animal level.

```{=html}
<!-- -->
```
-   Applications concerning the developmental biology or nutritional
    regulation of the immune system should be submitted to the Animal
    Protection and Biosecurity (44.0A): Animal Disease program element.
    Applications addressing developmental biology of the reproductive
    system, including embryonic, gonadal, and placental development, and
    applications dealing with nutritional regulation of reproduction,
    should be submitted to the Animal Reproduction program (41.0).
    Applications focusing on the effects of diseases or alterations in
    the immune system on animal growth, lactation or nutrient
    utilization, or those that emphasize nutritional regulation of
    animal health or immune function, should not be submitted to this
    program. Applications seeking to create functional foods (e.g. to
    increase the amount of omega-3 fatty acids, conjugated linoleic
    acids, or nutritional components in meat, milk, or eggs) should not
    be submitted to this program.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 56.0 Plant Biology 

[National Program Leaders]{.underline} −

> Dr. Liang-Shiou Lin (202-401-5042 or <llin@csrees.usda.gov>)
>
> Dr. Gail McLean (202-401-6060 or <gmclean@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$16.6 million, with
up to \$1.35 million for integrated projects

[Proposed Budget Requests]{.underline} − This program contains five
elements. See each program element for additional budgetary information.

> Plant Biology (A): Gene Function and Regulation
>
> Plant Biology (B): Environmental Stress
>
> Plant Biology (C): Biochemistry
>
> Plant Biology (D): Growth and Development
>
> Plant Biology (E): Plant Breeding and Education

[Letter of Intent]{.underline} − Required for each program element. See
the **Other Key Information** section of each program element for
additional details.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

This program supports projects that will provide fundamental knowledge
and training for improvement and sustainability of agricultural plant
and forestry production. Knowledge of plant biology from the molecular
to the systems level provides the foundation for development of plants
with increased productivity, fitness, and use. Such fundamental
understanding of plant biology will allow scientists to make use of the
increasing wealth of genomics data and tools and to develop new
varieties of agricultural plants through biotechnology and plant
breeding approaches.

The science-based knowledge and education contributed by this program
can lead to increased economic opportunities for producers and consumers
by reducing production costs, improving quality, and increasing value of
agricultural plant products. This knowledge will allow U.S. agriculture
to face critical needs in the areas of bioenergy, climate change, loss
of agricultural land, and increasing global competition.

In FY 2008, the program elements Plant Biology (A): Gene Function and
Regulation; Plant Biology (B): Environmental Stress; Plant Biology (C):
Biochemistry; and Plant Biology (D): Growth and Development are
soliciting research projects only. The program element Plant Biology
(E): Plant Breeding and Education is soliciting integrated projects
only. Please see specific program elements below for submission details
and element-specific instructions.

[56.0 Plant Biology (A): Gene Function and Regulation]{.underline}

[National Program Leader]{.underline} − Dr. Liang-Shiou Lin
(202-401-5042 or <llin@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3.45 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due October 9, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

The plant research community is poised to apply recent advances in plant
genomics to traits of economic value in important agricultural species.
For this application to occur, the basic genetic processes and
mechanisms must be well understood. The goal of this program element is
to supply such fundamental knowledge to support the development of
genetically superior varieties of crop and forest species that are more
cost-effective to grow and will provide greater profit for farmers in
the ever more competitive global market.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program element are to obtain a detailed understanding of
the function of agriculturally important genes and the regulation of
gene expression in agricultural plants to better use these genes for
improved crop and forest production and quality.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Functional analyses of agriculturally important genes in plants.
    Studies of plant disease/pest resistance genes are appropriate for
    this program but are limited in FY 2008 to studies focusing on genes
    conferring resistance to diseases caused by fungi, oomycetes,
    bacteria, or viruses. Studies on genes conferring resistance to
    arthropod or nematode pests are not solicited this year. Studies may
    also include the development of improved mutational and gene
    silencing approaches.

2.  Research on regulatory mechanisms of gene expression. Research is
    encouraged that aims at understanding gene regulatory networks at
    the systems level.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

```{=html}
<!-- -->
```
-   Format the letter with one-inch margins and six lines per inch and
    font no smaller than 12 point. The letter of intent must be
    submitted in portable document format (PDF).

-   The letter of intent is limited to two pages.

    -   On Page 1 include a cover letter with the following information:

        -   the name of the lead project director;

        -   the names of collaborating investigators; and

        -   the program priority addressed by the project.

    -   On Page 2 include

        -   a descriptive title; and

        -   a brief statement of approaches and objectives

-   Attach the PDF letter of intent to an email addressed to Dr.
    Liang-Shiou Lin (<llin@csrees.usda.gov>) with the subject heading\
    '*Letter of Intent Program 56.0A_PD's Last Name'*.

-   An acknowledgement receipt will be sent indicating the letter was
    received.

-   A letter of intent is not required for conference grant proposals,
    career enhancement grant proposals, equipment grant proposals, and
    seed grant proposals.

-   Letters of intent will be reviewed relative to suitability, scope,
    and needs of the program as delineated in the program description
    and priorities.

-   Submission of more than one letter of intent is discouraged.

-   Project Directors will receive a response from the National Program
    Leader inviting or rejecting a full application by **October 19,
    2007**. The National Program Leader will not provide feedback
    regarding content in the letter.

-   Only invited full applications will be reviewed by the panel.

```{=html}
<!-- -->
```
-   For the plant disease/pest resistance aspect of Research Priority 1,
    the program will focus on the following groups on a rotational
    basis: arthropods/nematodes, fungi/oomycetes, and bacteria/viruses.
    The anticipated priority rotation schedule is:

> FY 2009: bacteria/viruses and arthropods/nematodes
>
> FY 2010: arthropods/nematodes and fungi/oomycetes

-   Use of Model Species - Studies of non-agricultural model systems may
    still be submitted to the program if the knowledge gained is
    utilized for study of plants of economic or societal importance in
    the submitted project [and]{.underline} such study is a significant
    and integral component within the experimental design. This program
    will no longer accept projects solely using non-agricultural model
    species. Importance of the proposed research to agricultural
    productivity and sustainability should be clearly indicated in the
    application.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[56.0 Plant Biology (B): Environmental Stress]{.underline}

[National Program Leader]{.underline} − Dr. Gail McLean (202-401-6060 or
<gmclean@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$3.4 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$350,000
    for project period of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due October 9, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

The future of agricultural productivity and sustainability depends on
the ability of agricultural and forestry plants to grow and be
productive in response to a changing environment, for example in light
of short-term challenges, such as flooding, and long-term challenges,
such as global climate change, sustained drought, and loss of arable
land. This program element supports fundamental research projects to
improve plant tolerance and resistance to environmental stress.
Research, ranging from genomics to physiology, will provide the basic
knowledge to devise new or improved strategies for decreasing the impact
of environmental stress on agricultural and forest productivity and
sustainability.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program element are: to generate fundamental knowledge
regarding the genetic, genomic, molecular, physiological,
ecophysiological, and biochemical components involved in plant abiotic
stress response; to use fundamental knowledge to develop approaches and
tools to aid agricultural plant productivity in response to reduced
inputs or increased environmental stresses; and to develop, through
biotechnology and/or breeding, new plant lines or populations for
improved stress-resistance or tolerance in agricultural plants.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

Research should identify and/or characterize genes, proteins, processes,
and/or networks that contribute to abiotic stress tolerance for the
program priorities below. Applications must focus on characterization
and understanding of the mechanism(s) used by particular plant species
in adaptation to or tolerance of specific environmental condition(s).
Such research should be hypothesis-driven and may include molecular,
physiological, biochemical, and/or cell biological approaches.

1.  Water stress, including drought, salt, and flooding stress.

2.  Global change stress, including increased carbon dioxide, ozone.

3.  Temperature stress.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Gail McLean (<gmclean@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 56.0B_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
<!-- -->
```
-   Starting in FY 2009, proposals in the priority areas of Global
    Change, Nutrient Stress, and Temperature Stress will be solicited on
    a rotating basis. It is anticipated that proposals on Water Stress
    will continue to be solicited each year. The anticipated priority
    rotation schedule is:

> FY 2009: Global Change and Nutrient Stress
>
> FY 2010: Nutrient Stress and Temperature Stress
>
> FY 2011: Temperature Stress and Global Change

1.  

-   All applications must demonstrate a clear link to a realistic
    environmental problem and use realistic treatments and measurement
    of plant stress status and environmental conditions. Applications
    where the proposed research integrates molecular biology methods
    with physiological or ecophysiological approaches will be most
    competitive.

-   Research projects should be hypothesis-driven. Applications
    combining hypothesis-driven research and plant breeding techniques
    to develop products (germplasm) beneficial to the community are
    appropriate for this program element. Projects which develop
    stress-tolerant varieties without proposing research to characterize
    plant stress response mechanisms are not appropriate for the
    program. Phytoremediation and adaptation to biotic stresses, such as
    herbivory or pests, should not be submitted to this program. For
    applications containing ecosystem level studies, applicants should
    consider submission to the Managed Ecosystems program (23.1). For
    functional analyses of agriculturally important genes not directly
    related to abiotic plant stress mechanisms, applicants should
    consider submission to the Plant Biology (A): Gene Function and
    Regulation program element.

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-   Use of Model Species - Studies of non-agricultural model systems may
    still be submitted to the program if the knowledge gained is
    utilized for study of plants of economic or societal importance in
    the submitted project [and]{.underline} such study is a significant
    and integral component within the experimental design. This program
    will no longer accept projects solely using non-agricultural model
    species. Importance of the proposed research to agricultural
    productivity and sustainability should be clearly indicated in the
    application.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[56.0 Plant Biology (C): Biochemistry]{.underline}

[National Program Leader]{.underline} − Dr. Gail McLean (202-401-6060 or
<gmclean@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.2 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 26, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

Identification and characterization of biochemical processes and
pathways in the cell, as well as the genes and proteins involved in
biochemical processes and pathways, will facilitate development of
agricultural and forestry plants with improved or optimized performance.
The lack of knowledge about a biochemical pathway or process often
limits the application of genomic and genetic information in improving
agricultural plant and forest productivity, quality, and sustainability.
The goal of this program element is to provide basic knowledge about
biochemical processes, pathways, and interactions in agriculturally and
economically important plants and related organisms. Fundamental
knowledge in biochemistry, combined with genomics and other crop
improvement techniques, will lead to practical applications, such as
enhancing the nutritional value of plant-based foods, increasing the
productivity and fitness of agricultural plants and trees, better
utilizing trees and agricultural plants for sustainable production of
bioenergy, and developing agricultural plants as bioreactors to produce
important industrial compounds.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program element are: to contribute fundamental knowledge
of biochemical pathways, processes, and mechanisms for potential
utilization of genomic sequences in agricultural plants; to use
knowledge in plant biochemistry to increase plant production,
efficiency, and/or protection, to enhance nutrient content, utilization,
and/or uptake and to improve or develop new plant-based products; to
create improved agricultural plant lines or populations through use of
basic biochemical knowledge and biotechnology; and to develop at least
one reference agricultural species for biochemical studies.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

For the program priorities listed, research should be hypothesis-driven
and either focus on characterization of a biochemical process or pathway
important for plant agricultural production systems or address a
significant problem in agricultural plant biology using a predominantly
biochemical approach. Use of small-scale proteomics or metabolomics is
acceptable as part of a hypothesis-driven project to gain insight into
biological systems.

1.  Primary and secondary metabolism, with particular emphasis on
    improving plant productivity, fitness, or quality.

2.  Plant cell wall structure, formation, and modification, such as
    lignin, cellulose, or hemicellulose synthesis and modification.

3.  Photosynthesis and respiration with particular emphasis on
    increasing photosynthetic efficiency.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 26, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Gail McLean (<gmclean@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 56.0C_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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-   Starting in FY 2009, proposals in the priority areas of Cell Walls,
    Photosynthesis/Respiration, and Nitrogen Fixation will be solicited
    on a rotating basis. It is anticipated that proposals on Primary and
    Secondary Metabolism will continue to be solicited each year. The
    anticipated priority rotation schedule is:

> FY 2009: Plant Cell Wall and Nitrogen Fixation
>
> FY 2010: Nitrogen Fixation and Photosynthesis/Respiration
>
> FY 2011: Photosynthesis/Respiration and Plant Cell Wall

1.  

-   Use of Model Species: Importance of the proposed research to
    agricultural productivity and sustainability should be clearly
    indicated in the application. Researchers are strongly encouraged to
    conduct research directly in a crop or forest species important to
    agriculture. Use of non-agricultural model systems is acceptable if
    tools are not yet available in the agricultural species of interest.
    **However, the investigator must clearly indicate** (1) how such
    non-agricultural model studies are relevant to agriculture and food
    systems or forest species, (2) the strategy for transferring the
    knowledge to these species for agricultural or forestry benefit,
    and (3) the potential timeframe for such transfer.

-   Applications on phytoremediation and the biochemistry of pest
    management should not be submitted to this program. Applications
    that focus on plant environmental response and stress should
    consider submission to Plant Biology (B): Environmental Stress
    program element. Applications that focus on plant cell biology, such
    as studies on cytoskeleton, membrane transport, signal transduction,
    and macromolecular trafficking that are critical for plant
    development, should consider submission to the Plant Biology (D):
    Growth and Development program element unless the emphasis is on
    biochemistry, which will be supported by this program element. For
    functional analyses of agriculturally important genes related to
    plant disease, applicants should consider submission to Plant
    Biology (A): Gene Function and Regulation program element. For
    projects focused on metabolic engineering, the purposeful alteration
    of metabolic pathways to understand and use cellular pathways for
    chemical transformation, energy transduction, and supramolecular
    assembly, applicants may want to consider submission to the
    Interagency Metabolic Engineering program (see
    [http://www.metabolicengineering.gov](http://www.metabolicengineering.gov/)).

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[56.0 Plant Biology (D): Growth and Development]{.underline}

[National Program Leader]{.underline} − Dr. Liang-Shiou Lin
(202-401-5042 or <llin@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.2 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 26, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

The plant research community is poised to apply recent advances in plant
genomics to traits of economic value in important agricultural species.
For this application to occur, the fundamental knowledge on plant growth
and development must be well understood. The goal of this program
element is to provide such knowledge over various phases of the plant
life cycle to improve crop plants through modification of plant growth
patterns or developmental processes. This will provide greater profit
and less risk for U.S. farmers in the ever more competitive global
market.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program element are: to develop crop models for studying
plant developmental processes; to provide detailed understanding of
signal transduction mechanisms, such as hormones, light, gravity, etc.,
in agricultural plants in order to improve their performance; and to
enhance our ability to alter developmental processes of agricultural
plants to improve plant characteristics.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Developmental pathways leading to the formation of vegetative
    (particularly roots) or reproductive structures, including the
    development of gene profiling, genetic, and proteomic tools for
    these studies.

2.  Hormonal regulation of growth and development, including studies of
    "cross talk" between different hormones or between hormones and
    other signals. Use of metabolomic tools for these studies is
    encouraged.

3.  Characterization of cellular structures and processes that are
    crucial for plant development. Proposals that integrate cell biology
    with physiology are expected to be more competitive. In FY 2008,
    these studies are limited to cytoskeleton and membrane transport
    processes.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 26, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Liang-Shiou Lin (<llin@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 56.0D_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 10, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

        -   Research Priority 3 will focus on cytoskeleton, membrane
            transport, and macromolecular trafficking on a rotational
            basis. Investigators working on enzyme characterization or
            biochemical aspects of these studies should consult with the
            National Program Leader for the Plant Biology (C):
            Biochemistry program. The anticipated priority rotation
            schedule is:

> FY 2009: membrane transport and macromolecular trafficking
>
> FY 2010: macromolecular trafficking and cytoskeleton

-   Use of Model Species - Studies of non-agricultural model systems may
    still be submitted to the program if the knowledge gained is
    utilized for study of plants of economic or societal importance in
    the submitted project [and]{.underline} such study is a significant
    and integral component within the experimental design. This program
    will no longer accept projects solely using non-agricultural model
    species. Importance of the proposed research to agricultural
    productivity and sustainability should be clearly indicated in the
    application.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[56.0 Plant Biology (E): Plant Breeding and Education]{.underline}

[National Program Leaders]{.underline} −

> Dr. Liang-Shiou Lin (202-401-5042 or <llin@csrees.usda.gov>)
>
> Dr. Gail McLean (202-401-6060 or <gmclean@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$1.35 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed
    \$500,000 for project period of 2-4 years (including indirect
    costs)**.**

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due October 9, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

Plant breeding provides the genetic resources and diversity needed for
agricultural plant and forestry production to face challenges, such as
global change, increasing population size, decreasing land availability
and quality, and sustainable production of bioenergy and biobased
products. Whether through traditional approaches or combined with
biotechnology, plant breeding can enable development of new plant and
forestry varieties with desired traits, including improved pest and
plant disease resistance, enhanced flavor and nutritional content,
increased fecundity and productivity, enhanced environmental stress
tolerance, and new, alternative uses. These new varieties can provide
producers with increased economic opportunities and consumers with
affordable food, fiber, fuel, and other products with new qualities.
Education activities in plant breeding will aid in the transfer of
science-based knowledge to agricultural producers by providing necessary
expertise for plant biotechnology and breeding approaches and by
training future generations of plant breeders. The goal of this program
element is to support integrated research and education projects to
enhance germplasm and advance training in plant breeding in
agriculturally and economically important plant and forestry species.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program element are: to increase the number of students
and scientists trained in plant breeding and in careers requiring plant
breeding expertise; and to improve transfer of science-based knowledge
to producers and consumers through breeding or breeding combined with
biotechnology.

**FY 2008 Priority for Integrated Projects − Applicants must address at
least one of the following priorities.**

1.  Education and training in an academic setting to build expertise in
    plant breeding combined with research focusing on germplasm
    enhancement for abiotic environmental stress tolerance, with
    particular emphasis on drought tolerance.

2.  Education and training in an academic setting to build expertise in
    plant breeding combined with research focusing on germplasm
    enhancement for improved nutrient uptake and/or utilization, with
    particular emphasis on nitrogen.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one-inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to
        **[both]{.underline}** Dr. Liang-Shiou Lin
        (<llin@csrees.usda.gov>) [and]{.underline} Dr. Gail McLean
        (<gmclean@csrees.usda.gov>) with the subject heading '*Letter of
        Intent Program 56.0E_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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-   Applicants are encouraged to utilize germplasm from the National
    Plant Germplasm System (NPGS). Applications using specialty crops
    are encouraged.

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-   Integrated projects for this program element should include mutually
    dependent research and education objectives. These include: a)
    hypothesis-driven research to fill knowledge gaps that are critical
    to the development of practices and programs to address the problem
    area; and b) educational deliverables (e.g. interdisciplinary
    curricula and/or experiential learning for graduate and
    undergraduate students) that will train the next generation of
    scientists and educators who will work in the problem area. Projects
    should provide a plan for creating a stakeholder advisory board (if
    not already in place) and include the types of stakeholders who are
    expected to be involved and how their input would be used. Projects
    must also include a management plan (developed with input from
    stakeholder advisory groups) that leads to measurable improvements
    in the problem area. This management plan should provide information
    on how the team members will communicate including a schedule for
    communication.

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-   The education component of an integrated application must go beyond
    the level of laboratory training for graduate students or
    postdoctoral researchers supported by the grant. Examples of
    education activities in agricultural plant breeding and germplasm
    enhancement include curriculum and/or degree program development,
    multi-college/university approaches to regional or interstate
    curriculum development, faculty sharing, and joint degrees.
    Internships placing graduate or undergraduate students in industry,
    academic, or government settings for experiential learning in plant
    breeding technology are encouraged. The education component is
    expected to describe institutional resources and must clearly
    indicate how and why the proposed new curriculum or degree will
    complement, enhance, or replace any existing curriculum or programs
    at the institution. Projects should also include plans for
    assessment and performance outcome measurement, for continuation or
    expansion beyond the period of USDA support and potentially for
    tracking of participant accomplishments after course completion. The
    research component of an integrated application for this program
    element is not limited to biological problems and may include
    comprehensive studies to evaluate institutional capacity building
    and efficacy of established plant breeding education programs.

-   Integrated projects that identify and recruit undergraduate students
    for careers in plant breeding and for pipelining into graduate
    training in plant breeding are particularly encouraged.

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-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 61.0 Agribusiness Markets and Trade

[National Program Leader]{.underline} − Dr. S. (Suresh) Sureshwaran
(202-720-7536 or <ssureshwaran@csrees.usda.gov>)

[Total Program Funds]{.underline} − anticipated funding at approximately
\$ 5.1 million

[Proposed Budget Requests]{.underline} − **Not accepting applications
for FY 2008**

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − Agribusiness Markets and Trade will
not be offered in FY 2008. This program is offered in alternate years
and will be accepting applications again in FY 2009.

**Background**

Success of the U.S. economy in general, and agribusiness and rural
communities in particular, is increasingly dependent on maintaining and
expanding domestic and international markets. It is also dependent on
the development of new products, production practices, and business and
marketing tools and information that enhance efficiency, equity, and the
competitiveness of the producer. The Agribusiness Markets and Trade
program is designed to maintain and expand domestic and international
markets and to identify public policies and private strategies that may
be employed to enhance efficiency, equity, and the competitiveness of
the U.S. agribusiness sector.

Industrialization, increased concentration and the trend towards
industrial clusters in agriculture, has caused concern about the
long-run structure and viability of the agricultural sector. To maintain
and enhance the efficiency and equity of the U.S. agribusiness sector,
new science based information is continuously needed, especially on the
structure, conduct, and performance of firms in different industries;
effects of integration on producers, prices, etc; and the impacts of
food chain clusters on independent producers, markets, etc. To maintain
and expand international market opportunities for U.S. agribusiness,
more research is needed on rapid changes in consumer demand for
agricultural products, the impacts of expanding agricultural markets on
domestic producers and consumers, the benefits and costs of regulation,
and alternative market solutions; the influence of existing and new
policy and technology, etc. The competitiveness of the U.S. agribusiness
sector is determined by new product development and placement of these
products in the value chain. Therefore, to enhance competitiveness, the
agribusiness sector needs research based information on marketing new
products, including packaging, labeling, etc; on product
differentiation, including characteristics, production process,
geographic origin, etc; impacts of changing demand patterns for
differentiated products, etc.

The Agribusiness Markets and Trade program seeks to achieve three
objectives during the next ten years: (1) provide knowledge to enhance
economic efficiency and equity in U.S. agribusiness sector; (2) support
research that builds international market opportunities; and (3) provide
economic analysis to assist with new product development and insertion
in the value chain.

**FY 2009 Priority for Research**

1.  Enhance understanding of the changes in agribusiness structure and
    conduct, as well as its effectiveness in the development of markets
    at home and abroad.

2.  Provide knowledge to increase market access and reduce trade
    impediments for major agricultural products.

3.  Develop new models and theories to enhance understanding of changes
    in domestic and foreign consumer tastes and preferences.

### 71.2 Biobased Products and Bioenergy Production Research 

[National Program Leader]{.underline} − Dr. Chavonda Jacobs-Young
(202-401-6188 or <cjacobs@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.4 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$500,000
    for project period of 3-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent Deadline]{.underline} − November 2, 2007 (5:00 P.M.,
ET); see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − January 17, 2008 (5:00P.M., ET)

**Background**

The Biobased Products and Bioenergy Production Research program supports
fulfillment of the Energy Policy Act of 2005(P.L. 109-58) to promote
dependable, affordable, and environmentally sound production and
distribution of energy for America's future, available at
<http://www.epa.gov/oust/fedlaws/publ_109-058.pdf> . Fulfillment of the
Act also includes promoting research and development leading to the
production of biobased industrial products. The program, through
improving the utilization of forestry residuals, supports the [Healthy
Forests Restoration Act of 2003 (P.L. 108-148)]{.underline} that seeks
to reduce forest wildfires through the creation of healthy forests by
the thinning of undergrowth and trees in nearly 20 million acres of
federal lands, available at <http://www.healthyforests.gov/index.html> .

Program activities will expand science-based knowledge and technologies
to support the efficient, economical, and environmentally friendly
conversion of biomass, more specifically agricultural and forestry
residuals, into value-added industrial products and biofuels.

The long term goals (10-years) for the program include increasing the
production of fuels, chemicals, and materials from biomass; increasing
the inventory of biobased products for replacement of petroleum based
products; and reducing the costs associated with the conversion of
biomass to fuels and industrial products by developing biocatalysts that
can convert low cost agricultural and forestry feedstocks.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

The program will support research to advance the biological conversion
of post-harvest lignocellulosic biomass to value-added industrial
products and fuels. Specific priorities for FY 2008 include:

1.  Improvement/Development of cost effective biocatalysts. The program
    is specifically seeking applications that produce biocatalysts more
    resistant to inhibitors, capable of degrading multiple sugar types,
    and capable of increasing product yield in the biological conversion
    of agricultural and forestry lignocellulosic biomass to value-added
    industrial products and fuels.

2.  Improved production and processing technologies to facilitate the
    biological conversion of agricultural and forestry lignocellulosic
    biomass to aid in the production of high-value industrial biobased
    products and fuels. The program is seeking applications that
    specifically address the long term goal of simultaneous
    saccharification and fermentation and other conversion steps
    limiting the technical and economic efficiency of the biological
    production of fuels and industrial biobased products from
    agricultural and forestry residuals.

3.  Novel, cost effective, and affordable agriculturally-based
    co-products and industrial biobased products that are direct
    substitutes for traditionally petroleum based products. Products
    must be innovative and demonstrate the potential for economic
    competitiveness within the next 10 years.

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2.  

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 2, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Chavonda Jacobs-Young (<cjacobs@csrees.usda.gov>) with the
        subject heading\
        '*Letter of Intent Program 71.2_PD's Last Name*'.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **November 21, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

-   Applications that focus on plant biochemistry should be submitted to
    the Plant Biology (C): Biochemistry program. Applications focused on
    plant genetics should be submitted to the Plant Biology (A): Gene
    Function and Regulation program. Animal feed, fertilizer,
    bioremediation, thermo-chemical processes (i.e. pyrolysis,
    gasification, syngas production or conversion), algae, market
    analysis, and economic analysis applications should not be submitted
    to this program.

-   Engine performance testing and emissions characterization will not
    be supported.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 75.0 Nanoscale Science and Engineering for Agriculture and Food Systems

[National Program Leader]{.underline} − Dr. Hongda Chen (202-401-6497 or
<hchen@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests with emphasis on high
    risk/high return "proof of concept" studies must not exceed
    \$100,000 (including indirect costs).

-   Proposed research project requests must not exceed \$300,000 for
    project period of 2-4 years (including indirect costs) for single
    investigator led projects.

-   Proposed standard research project budget requests must not exceed
    \$500,000 for project period of 3-4 years (including indirect costs)
    for multidisciplinary projects.

-   NEW: Up to three projects at no more than \$200,000 each for project
    period of 2-4 years (including indirect costs) for addressing
    societal issues as defined in the Priorities for Research section
    below.

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − January 17, 2008 (5:00 P.M., ET)

**Background**

Nanoscale science, engineering, and technology, herein referred to as
nanotechnology for brevity, is the fundamental understanding and
technological advances arising from the exploitation of new physical,
chemical, and biological properties of matter at the length of scale of
approximately 1 to 100 nanometers. Exciting novel structures, phenomena,
and processes have been observed at the nanoscale in recent years and
new experimental, theoretical, and simulation tools have been developed
for investigating them. Nanotechnology, as a new enabling technology,
has the potential to revolutionize agriculture and food systems. In a
concerted effort with the National Nanotechnology Initiative (NNI), this
interagency program spearheads nanoscale science and engineering
research relevant to agriculture and food systems.

To meet the identified needs of agriculture, the ultimate goal of this
program is to provide knowledge, expertise, and highly qualified R&D
human capital for nanoscale science, engineering, and technology for
food and agricultural systems. The specific long term (10 year) goals
are to build a rich set of knowledge matrices to effectively aid the
design of nano-based devices and systems, which are highly sensitive and
specific for monitoring, detection, and intervention of food quality,
safety, and biosecurity; to develop a mature knowledge base of nanoscale
processing, product formulation, and shelf-stability of food with
enhanced nutrition value as a part of individualized health management
(IHM) practices; and to develop the capability to integrate nano-based
product identification and tracking technologies compatible with the
contemporary IT and other auxiliary technologies to build functional
devices and systems to aid knowledge management throughout agriculture
and food production to the consumption chain.

Responsible development and deployment of nanotechnology is one of the
four principal goals of the 2004 NNI Strategic Plan. The broad societal
dimensions of nanotechnology must be proactively addressed to assure a
societally acceptable and public supported course for developing new
nanotechnologies and novel products. Public engagement, namely providing
information to and seeking input from the public, will allow the
Government to make well-informed decisions and build trust among all
stakeholders. Public perception and acceptance of nanotechnology and new
products are especially critical in the realization of societal benefits
of nanotechnology research and development for agriculture and food
systems. Social science research, including economics, law, ethics,
sociology, policy and governance, communications and others, will
provide useful insight of the societal dimensions of developing
nanotechnology.

**FY2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Nanoscale recognition, reception, and transmission mechanisms and
    novel materials for developing nanobased sensors specifically for
    targets important to food safety and agriculture biosecurity.

2.  Novel nanoscale processes, materials, and systems with improved
    delivery efficacy, controlled release, modification of sensory
    attributes, and protection of micronutrients and functional
    ingredients suitable for food matrices.

3.  Understanding nanoscale phenomena and processes to support the
    development of nano-based technologies for food and agricultural
    product quality monitoring, identity tracking, and preservation.

4.  NEW: Assessment and analysis of perceptions and acceptance of
    nanotechnology and nano-based products by the general public,
    agriculture, and food stakeholders using appropriate social science
    tools.

**Other Key Information**

-   Applications for studying the public perceptions and acceptance of
    nanotechnology for agriculture and food systems are required to link
    with the NRI or other NNI agency funded research projects relevant
    to agriculture and food production and processes to foster
    interdisciplinary dialogues and collaboration, as well as to assure
    high relevance. To view the information of the NRI funded
    nanotechnology research project, please see the webpage
    [http://cris.csrees.usda.gov/cgi-bin/starfinder/0?path=nrinselink.txt&id=anon&pass=&search=CG=\*-35603-\*%20NOT%20PS=TERM\*&format=WEBTITLESG](http://cris.csrees.usda.gov/cgi-bin/starfinder/0?path=nrinselink.txt&id=anon&pass=&search=CG=*-35603-* NOT PS=TERM*&format=WEBTITLESG).

-   Applications dealing with broad societal impacts of nanotechnology
    are encouraged to submit to the NSF led cross-disciplinary research
    programs.

-   Applications dealing with safety, health, and environmental
    implications, both beneficial and risk oriented, should be directed
    to the NNI interagency solicitation (<http://nano.gov/>).

-   Applications seeking support to develop educational opportunities,
    such as curriculum development and graduate fellowships, should
    consult the program staff of CSREES Science and Education Resources
    Development (SERD). National Science Foundation has provided strong
    supports through several programs, including the National Informal
    Science Education (NISE) Network and the National Center for
    Learning and Teaching in Nanoscale Science and Engineering
    (<http://nano.gov/>).

-   Applications seeking support to bridge benchtop discovery to
    commercialization should consult the CSREES National Program Leaders
    of the Small Business Innovation Research (SBIR) program for various
    funding opportunities.
    <http://www.csrees.usda.gov/funding/sbir/sbir.html>.

-   Applications that do not address at least one of the stated research
    program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

## Nutrition, Food Safety and Quality Cluster Overview

The Nutrition, Food Safety and Quality program cluster addresses CSREES'
strategic goals to improve the Nation's nutrition and health, to enhance
protection and safety of the Nation's agriculture and food supply and to
enhance economic opportunities for agricultural producers.

The maintenance of human health is significantly affected by the
quantity and types of food consumed and foods that are contaminated with
disease-causing microorganisms or toxins. Nutrition, obesity prevention,
and food safety are of paramount importance to the producer, processor,
distributor, and consumer. The overall goals of the Nutrition, Food
Safety and Quality program cluster are to:

1.  Improve our understanding of the behavioral and environmental
    factors that influence obesity and lead to the development and
    evaluation of effective interventions for obesity prevention.

2.  Contribute to our knowledge of the requirements and bioavailability
    of food components and factors, including food processing
    technologies and interrelationships among dietary components that
    impact optimal human nutrition or food quality.

3.  Increase our understanding of disease-causing pathogens and toxins,
    the risk factors that influence food-borne organisms and food
    safety, and the risk factors that lead to the development and
    implementation of mitigation or control strategies.

Data generated from these studies will be used for updating dietary
recommendations, formulating National nutrition and food safety policy,
and stimulating new product developments by the food industry.

In FY 2008 the NRI invites applications in the following cluster of
programs related to Nutrition, Food Safety and Quality:

> [31.0 Bioactive Food Components for Optimal Health]{.underline}
>
> [31.5 Human Nutrition and Obesity]{.underline}
>
> [32.0 Food Safety and Epidemiology]{.underline}
>
> [71.1 Improving Food Quality and Value]{.underline}

## Nutrition, Food Safety and Quality Program Descriptions

### 31.0 Bioactive Food Components for Optimal Health

[National Program Leader]{.underline} − Dr. Etta Saltos (202-401-5178 or
[esaltos@csrees.usda.gov]{.underline})

[Total Program Funds]{.underline} − approximately \$4.6 million, with up
to \$1.5 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$500,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$750,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 5, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − January 17, 2008 (5:00 P.M., ET)

**Background**

The consumption of a nutritious diet is important for maintaining
long-term health and decreasing the risk for chronic disease. The
primary objective of this program is to support research to improve our
understanding of the role of foods and their biologically active
components in promoting health throughout the life cycle, including
pregnancy, early development, and aging. Bioactive food components are
constituents in foods, other than those needed to meet basic human
nutritional requirements that are responsible for changes in health
status. This program also continues to support novel research regarding
the function of nutrients. Program objectives are relevant to the
research recommendations outlined in the Report of the Dietary
Guidelines Advisory Committee on the Dietary Guidelines for Americans,
2005.

To meet these identified needs of agriculture, the long-term (10-year)
goal of the program is to provide evidence concerning health effects of
bioactive food components that can be used by scientific organizations
in setting dietary reference intakes and tolerable upper limits for such
components (e.g. omega-3 fatty acids, conjugated linoleic acid, soy
phytoestrogens, and resveratrol). The program will coordinate with other
NRI programs in supporting the development of novel and health-enhancing
foods.

**FY 2008 Priority for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Mechanistic studies of the bioavailability, function, efficacy, and
    safety of bioactive dietary components at levels that would be
    expected to be consumed in the diet.

2.  Interrelationships among bioactive dietary components and/or
    nutrients in promoting health.

3.  Novel studies of the functions and mechanisms of regulation of
    vitamins and minerals.

**Other Key Information for Research Projects**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 5, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Etta Saltos (<esaltos@csrees.usda.gov>) with the subject heading
        '*Letter of Intent Program 31.0_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **November 21, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel

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-   Projects to develop biomarkers to measure human health outcomes,
    projects using dose-response methodology, or projects that use
    agriculturally important domestic species as models for human health
    outcomes are encouraged.

-   Applications dealing with food processing techniques should consider
    submission to the Improving Food Quality and Value program (71.1)
    unless they are clearly oriented toward dietary effects on optimal
    human health. 

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-   Support will [not]{.underline} be provided for research on the
    development of dietary supplements, research on dietary therapies
    for metabolic disorders, infectious diseases, cancer, and
    alcohol-related disorders, or for the establishment, expansion, or
    maintenance of dietary databases**.**

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-   Surveys of the nutritional status of population groups are not
    acceptable for this program, but may qualify for submission to the
    Human Nutrition and Obesity program (31.5).

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priority for Integrated Projects − Applicants must address at
least one of the following priorities.**

1.  *This is a shared priority of Programs 31.0 and 71.1.*
    Identification, processing, and tailoring of functional foods to
    promote energy balance, with an emphasis on efficacy and safety.
    Integrated projects should include a whole foods approach to
    developing functional foods that promote energy balance and optimal
    health.

    a.  Applicants integrating extension with other components should
        document evidence for stakeholder involvement in the development
        and implementation of the project.  Stakeholders may include
        consumers or representatives from industry.

    b.  Applicants are strongly encouraged to seek collaboration with
        industry.

    c.  Where applicable, use of populations at high-risk for developing
        obesity in studies is strongly encouraged.

    d.  Projects should include expertise in multiple disciplines,
        including nutrition and food science.

    e.  Projects that incorporate interdisciplinary training of graduate
        students and postdoctoral researchers in nutrition, food
        science, and related disciplines are strongly encouraged.

**Other Key Information for Integrated Projects**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 5, 2007, by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Etta Saltos (<estaltos@csrees.usda.gov>) with the subject
        heading '*Letter of Intent Program 31.0_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **November 21, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel

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-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

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```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

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```
-   Surveys of the nutritional status of population groups are not
    acceptable for this program, but may qualify for submission to the
    Human Nutrition and Obesity program (31.5).

    -   Applications that do not address the stated integrated program
        priority will be returned without review.

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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[]{#_31.5_Human_Nutrition .anchor}

### 31.5 Human Nutrition and Obesity

[National Program Leaders]{.underline} −

> Dr. Etta Saltos (202-401-5178 or <esaltos@csrees.usda.gov>)
>
> Dr. Susan Welsh (202-720-5544 or <swelsh@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$10.5 million, with
up to \$9.5 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$500,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed \$1.5
    million for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests over \$1 million are
    expected to be multi-investigator or multi-institutional (including
    indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

This crosscutting program addresses the complex problem of obesity
prevention. Projects funded by this program should lead to a better
understanding of the behavioral and environmental factors that influence
obesity and to the development and evaluation of effective interventions
to prevent obesity. Obesity is the number one nutritional problem in
America. Food is an integral part of the process that leads to obesity
and USDA has a unique responsibility for the food system in the United
States.

To meet the identified needs of agriculture, the long-term (10-year)
goals for this program include identifying the behavioral and
environmental factors that influence obesity to develop effective
obesity prevention strategies; developing valid behavioral and
environmental instruments for measuring progress in obesity prevention
efforts; and promoting effective strategies for preventing overweight
and obesity. The ultimate goal of the program is to stem the rising tide
of obesity.

The milestones toward reaching these long-term goals include developing
theories on how behavioral and environmental factors influence obesity;
testing validity of behavioral and environmental measures for evaluating
progress in obesity prevention efforts; and testing the effectiveness of
strategies for preventing overweight and obesity.

**FY 2008 Priority for Integrated Projects − Applicants must address at
least one of the following priorities.**

1.  Improve understanding of the behavioral and environmental factors
    that influence obesity and use this new information to develop
    effective intervention strategies for preventing overweight and
    obesity and/or develop educational programs to help prepare the next
    generation of researchers and educators to address the complex
    problems of obesity. See Other Key Information -- Research and
    Integrated Projects below for examples of priority focus areas.

2.  Develop and implement behavioral and environmental instruments to
    measure progress in obesity prevention efforts. This activity may
    necessitate the development of new instruments or the modification
    and validation of existing ones related to food, physical activity,
    and environmental factors.

**Other Key Information for Integrated Projects**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
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```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
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```
-   Complex projects involving multiple institutions or functions should
    include a management plan that demonstrates that the project will be
    carried out efficiently.

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-   Because food is an integral part of the development of obesity, all
    projects should address some aspect of food from production to
    consumption. Because obesity is such a multifaceted problem, it is
    expected that the project team will have appropriate training and
    experience in multiple disciplines, especially nutrition.

-   Potential study areas for factors influencing obesity may include
    social and psychological factors, the role of lifestyle, including
    physical activity, as well as the influence of family, peers, and
    community, the influence of the physical environment, economic
    factors, and agricultural and public policy issues.

-   Priority will be given to projects involving population groups at
    risk for obesity, such as children, racial and ethnic minorities,
    and those with limited resources, such as those served by USDA's
    Expanded Food and Nutrition Education program, Cooperative
    Extension, and nutrition assistance programs. The rationale for the
    selection of a particular population group, community, or market
    segment for study or intervention should be documented.

-   Graduate student participation in projects is encouraged.

-   Applications that focus on the use of functional foods to prevent
    obesity should consider submission to the Bioactive Food Components
    for Optimal Health program (31.0). Applications that focus on food
    processing or production related to energy balance should consider
    submission to the Improving Food Quality and Value program (71.1).
    Applications that focus primarily on medical therapies for disease
    should not be submitted to this program.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priority for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Improve understanding of the behavioral and environmental factors
    that influence obesity. See Other Key Information for examples of
    priority focus areas.

2.  Epidemiological studies related to these priorities may involve
    secondary analyses of large national databases.

**Other Key Information for Research Projects**

-   Because food is an integral part of the development of obesity, all
    projects should address some aspect of food from production to
    consumption. Because obesity is such a multifaceted problem, it is
    expected that the project team will have appropriate training and
    experience in multiple disciplines, especially nutrition.

-   Potential study areas for factors influencing obesity may include
    social and psychological factors, the role of lifestyle, including
    physical activity, as well as the influence of family, peers, and
    community, the influence of the physical environment, economic
    factors, and agricultural and public policy issues.

-   Priority will be given to projects involving population groups at
    risk for obesity, such as children, racial and ethnic minorities,
    and those with limited resources, such as those served by USDA's
    Expanded Food and Nutrition Education program, Cooperative
    Extension, and nutrition assistance programs. The rationale for the
    selection of a particular population group, community, market
    segment, or intervention group should be documented.

-   Graduate student participation in projects is encouraged.

-   Applications that focus on metabolism or on the use of functional
    foods to prevent obesity should consider submission to the Bioactive
    Food Components for Optimal Health program (31.0). Applications that
    focus on food processing or production related to energy balance
    should consider submission to the Improving Food Quality and Value
    program (71.1). Applications that focus primarily on medical
    therapies for disease should not be submitted to this program.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 32.0 Food Safety and Epidemiology

[National Program Leaders]{.underline} −

> Dr. Chris Wozniak (202-401-6020 or <cwozniak@csrees.usda.gov>)

Dr. Mary E. Torrence (202-401-6357 or <mtorrence@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$10.2 million

[Proposed Budget Requests]{.underline} − This program contains two
elements. See each program element for additional budgetary information.

> Food Safety and Epidemiology (A): Biological Approaches for Food
> Safety
>
> Food Safety and Epidemiology (B): Epidemiological Approaches for Food
> Safety

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − See each program element for
additional details.

**Overview**

The area of food safety remains a high National priority. This is
especially true given recent concerns with bioterrorism and food-borne
outbreaks in produce, seafood, and other foods. Food safety research is
necessary to fill data gaps and reduce the incidence of food-borne
disease on the health care system. Research is needed to understand the
emergence, persistence, and transmission of food-borne organisms, as
well as to develop better interventions and control and prevention
strategies along the entire food safety continuum. Food production is a
highly complex set of systems that spans microbial, chemical, and
physical hazards. Therefore, improved food safety is a shared
responsibility.

The complex nature of food safety necessitates multi-disciplinary
solutions. Integration of microbiology, epidemiology, animal science,
plant pathology, veterinary medicine, food science, virology, and many
other disciplines are vital for the success of research and educational
outcomes. The goal of this program is to fund research efforts that
provide an increased knowledge of food-borne organisms and disease, and
reduce food-borne illness.

[32.0 Food Safety and Epidemiology (A): Biological Approaches for Food
Safety]{.underline}

[National Program Leader]{.underline} − Dr. Chris Wozniak (202-401-6020
or <cwozniak@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5.2 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

One of the main objectives of this program is to fund research efforts
that result in a demonstrable reduction in food-borne illness. This
program supports hypothesis driven research that seeks to increase our
knowledge of microbial ecology with regard to the routes of
contamination of food; this includes on-farm investigations,
post-harvest incidence, processing, and distribution of food. Aspects of
microbial ecology that provide for avenues of intervention and
mitigation of food-borne illnesses or toxicities are also relevant to
this program.

The long-term (10-year) goals of this program are to reduce the number
of food-borne illnesses in the U.S. and provide for the safe and
economic regulation of food safety issues. A primary function of this
program is to provide data and information to risk assessors
investigating emerging and ongoing food safety problems. In this regard,
areas of focus will be assessed year to year to re-examine priorities
and adjust the emphasis in response to emerging issues, as appropriate.

**FY 2008 Priorities for Research − Applicants must address at least one
of the following priorities.**

1.  Human enteric viruses, *Vibrio* spp., *Salmonella spp.*, Listeria*,*
    or microbial toxins associated with seafood: Proposed studies need
    to address imposition of mitigation measures aimed at reducing the
    incidence of human enteric viruses *Vibrio spp*., *Salmonella spp.*,
    and microbial toxins in shellfish, finfish, and derived products.
    Focus on harvesting methods, post-harvest storage, or processing
    technologies should include practical methods to reduce pathogen
    load.

2.  Human enteric viruses, *E. coli, Salmonella spp.*, Listeria, or
    microbial toxins on fresh fruits, nuts, and vegetables: Proposed
    studies need to address mitigation measures aimed at reducing
    colonization by these pathogens or cross contamination during
    packaging and processing of fresh produce, including fruits, nuts,
    vegetables, and sprouts, which undergo minimal processing
    post-harvest; multiplication on or within produce; or
    sensor/detection methodologies linked to practical mitigation
    measures. Studies elucidating the source and persistence of
    pathogens in the environment, as they relate to fresh produce and
    production of toxins, are included.

3.  *Salmonella spp.* or *Campylobacter spp.* in poultry and swine:
    Proposed studies need to address the pathogen load of *Salmonella
    spp.* or *Campylobacter spp.* on farm and the methods of
    transmission to poultry and swine; effective mitigation measures
    during processing and distribution; or genetics of strain
    development for antibiotic resistance as it relates to enhanced
    colonization or pathogen load and other virulence determinants.

**Other Key Information**

-   Fresh fruits, nuts, and vegetables include those sold without
    processing and fresh-cut: fresh fruits and vegetables for human
    consumption that have been peeled, sliced, chopped, shredded, cored,
    trimmed, or mashed, with or without washing, prior to being packaged
    (e.g. pre-cut, packaged, ready-to-eat salad mixes). Studies directed
    at irrigation, water re-use, and related hydrological issues as they
    pertain to food safety should consider submission to the Water and
    Watersheds program (26.0). Proposed studies that focus on worker
    hygiene as it relates to produce contamination or contain an
    integrated approach involving extension or educational components
    should consider submission to the Integrated Research, Education,
    and Extension Competitive Grants Program National Integrated Food
    Safety Initiative for submission of applications
    (<http://www.csrees.usda.gov/funding/rfas/food_safety.html>).

-   Surveillance as a principal objective is not suitable for this
    program. Research to quantify or monitor the incidence of organisms
    or toxins responsible for food-borne illness must also seek to
    ascertain other aspects of virulence, pathogenicity, biochemistry of
    toxin production, ecology, or genetics in addition to the
    enumeration of incidence, pathogen load, or frequency.

-   Research proposed to examine antibiotic resistance mechanisms must
    include a direct connection to food safety. Studies which focus on
    an examination of molecular mechanisms or incidence of antibiotic
    resistance within populations will not be considered for funding
    unless they consider aspects of antibiotic resistance associated
    with increased probability of food-borne illness (e.g. colonization
    potential, increased pathogen load, persistence, and viability).
    Antibiotic resistance as it relates to therapeutic treatment of
    humans or the etiology of pathogenesis will not be considered within
    this program.

-   Applications that contain hypothesis driven research targeting
    improved or novel detection methods for the designated
    microorganisms will be considered for funding; however, they must be
    of direct value in mitigating, reducing, or managing the offending
    agent or disease causing entity or in providing a greater
    understanding of the routes of food contamination, environmental
    persistence, and the biology of the offending agent. Research aimed
    solely at development of a detection methodology will not be
    considered for review. Applicants are encouraged to speak with the
    National Program Leader before submission of applications regarding
    detection methodologies. Coordinating the proposed study with the
    appropriate industry is highly recommended.

-   Applications may be structured from a pre-harvest or post-harvest
    approach as appropriate. Economic or model-based analyses of these
    priority areas will also be considered for review, especially if
    they address issues of regulatory burden and impacts on trade.

-   Applications dealing with food processing techniques or the
    utilization and production of foods designed to improve food quality
    should consider submission to the Improving Food Quality and Value
    program (71.1). Food safety applications examining the
    epidemiological aspects of microbes associated with food-borne
    illness should consider submission to the Epidemiological Approaches
    for Food Safety program (32.0 B).

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

[32.0 Food Safety and Epidemiology (B): Epidemiological Approaches for
Food Safety]{.underline}

[National Program Leader]{.underline} − Dr. Mary E. Torrence
(202-401-6357 or <mtorrence@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$1 million for
    project period of 3-4 years (including indirect costs).

-   Requests exceeding the budgetary guideline above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − December 19, 2007 (5:00 pm, ET)

**Background**

Epidemiological studies are necessary to develop an understanding of the
factors involved in food safety and provide the science-based data for
policy decisions. Epidemiological studies of pre- and post-harvest areas
are vital to identify and characterize pathogenic organisms, including
their sources and reservoirs, and to understand the transmission of the
pathogen along the entire continuum. These goals may be achieved using
several different epidemiological research methodologies. Environmental
and ecological data are needed to increase our understanding of
disease-causing microorganisms, their products, and naturally occurring
contaminants in meats, poultry, seafood, and fresh fruits and
vegetables. Understanding the distribution and determinants of disease
and health-related events in a population may be used for prevention and
control. Projects should focus on interactions among the environment,
agriculture, and human populations with the goal of decreasing
food-borne disease, as well as antimicrobial resistance.

The long term goals (10-year) for this program include enhancing the
epidemiologic methods available for the study of food-borne diseases and
other public health issues, advancing the understanding of the
epidemiology of food-borne disease and the food system on a continuum,
and providing more recommendations for specific intervention
strategies/prevention and control programs for food-borne disease and
antimicrobial resistance.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Development of [novel]{.underline} epidemiologic approaches (with or
    without a microbial component) that will provide the ability to
    [evaluate]{.underline} the impact of intervention or management
    strategies on microbial contamination or food safety. These may
    include epidemiological methods that will facilitate the
    understanding of quantitative data on pathogen load within the
    farm-to-fork continuum and facilitate the linking of\
    pre-harvest and post-harvest food safety outcomes to public health
    outcomes.

2.  Innovative studies which seek to [quantify]{.underline} the
    effectiveness of new or existing interventions or management
    strategies in reducing pathogen loads across farm-to-fork.

3.  Innovative studies which seek to [identify new]{.underline} risk
    factors or [quantitative evaluation]{.underline} of existing risk
    factors that may affect prevalence, transmission, or persistence of
    food-borne organisms across the farm-to-fork continuum.

**Other Key Information**

-   Near term goals that will help fulfill the long term goals
    include: 1) emphasizing new innovative epidemiologic and statistical
    methodology; 2) emphasizing more intervention studies and
    discouraging simple prevalence studies; and 3) emphasizing potential
    projects/methodologies for emerging issues in food safety and public
    health, including food biosecurity and antimicrobial resistance. One
    parallel activity will be to encourage the food safety Coordinated
    Agricultural Project (CAP) to fund high risk pilot research that can
    be used as preliminary data for epidemiologic applications and to
    encourage research and methods for dealing with emerging issues,
    specifically food biosecurity.

-   Proposals should involve collaboration with institutions,
    organizations, and communities of interest. Strong partnerships are
    encouraged, such as those that form consortiums or collaborative
    networks. Innovative multidisciplinary collaborations and
    partnerships are those designed to build solutions to understanding
    the interrelationships of the various factors that affect the safety
    of our food supply. Applications that combine the knowledge of
    multiple disciplines (i.e. veterinarians, food microbiologists,
    epidemiologists, public health specialists, or other scientific
    disciplines) are encouraged to develop the comprehensive
    understanding needed to solve complex problems.

    -   Applications [must have]{.underline} a primary central focus on
        population-based epidemiological studies. The applications [must
        have]{.underline} an epidemiologist as an active participant of
        the study, such as a co-investigator.

    -   Population-based studies that provide data for identified data
        gaps from risk assessments or provide epidemiologic data for
        on-going risk assessments will be considered.

    -   Applications focusing on method developments should be submitted
        to the Biological Approaches for Food Safety program (32.0 A).
        Applications concentrating on laboratory methods or techniques
        prevalence studies or studies that have already been done, pure
        risk assessment methodologies or modeling studies, and
        surveillance studies without additional components are **NOT**
        eligible.

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    ```
    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 71.1 Improving Food Quality and Value 

[National Program Leaders]{.underline} −

Dr. Ram Rao at (202-401-6010 or <rrao@csrees.usda.gov> )

Dr. Hongda Chen at (202-401-6497 or <hchen@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$6.5 million, with up
to \$1.5 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$300,000 for
    project period of 2-4 years (including indirect costs) for single
    investigator led projects.

-   Proposed research budget requests must not exceed \$500,000 for
    project period of 2-4 years (including indirect costs) for
    multidisciplinary and multiple researchers or multi-institution
    projects.

-   Proposed integrated project budget requests must not exceed
    \$750,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 5, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − January 17, 2008 (5:00 P.M., ET)

**Background**

Improving food quality and value is driven by the application of
physical, chemical, and biological principles and is essential in
meeting the needs of the consumer, as well as enhancing competitiveness
in global markets.

The long term goals (10-year) of this program are to formulate
ingredients based on the knowledge of chemical and physical interactions
for better functionality of foods; develop new and improved technologies
to produce better foods; and produce foods to promote optimum health of
individual citizens.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Basic mechanisms involved in the interaction of micro- and
    macro-molecules in the food matrix (e.g. protein-polysaccharide
    interaction) in controlling structure, texture, stability, and
    flavor delivery in foods. This includes (a) the fundamental
    understanding of the mechanism of interaction of proteins,
    polysaccharides, and lipids in foods (e.g. covalent, ionic,
    hydrophilic, and hydrophobic structures and kinetics) and (b)
    factors influencing the complexation and segregation of these
    macromolecules (e.g. processing environment, storage conditions,
    other food ingredients), and the resultant quality of foods (such as
    predictive modeling and food product quality).

2.  Advanced and innovative processing, engineering, and technologies
    that enhance food quality attributes and development and application
    of analytical characterization techniques of physical, chemical,
    biological, and sensory natures.

3.  Chemistry and fates of proven bioactive compounds in foods and food
    ingredients during processing, packaging, storage, distribution, and
    delivery.

**Other Key Information for Research Projects**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 5, 2007, by 5:00 P.M., Eastern Time**.
    Please use the formatting guidelines below. Format the letter with
    one inch margins and six lines per inch and font no smaller than 12
    point. The letter of intent must be submitted in portable document
    format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director and institutional
                affiliation;

            -   the names of collaborating investigators and
                institutional affiliation; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr. Ram
        Rao at <rrao@csrees.usda.gov> with the subject heading '*Letter
        of Intent Program 71.1_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **November 21, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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-   Improving Food Quality and Value program funds applications in the
    post harvest area.

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-   Multi-disciplinary approaches are highly encouraged.

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```
-   Applications addressing combined and inseparable quality and safety
    objectives will be entertained in this program. However,
    applications dealing primarily with issues of food safety should
    consider submission to the Food Safety and Epidemiology program
    (32.0). Applications dealing with bioavailability, metabolism, and
    mechanism of action of bioactive food components should be sent to
    the Bioactive Food Components for Optimal Health program (31.0).

-   Applications that do not address at least one of the stated research
    program priorities will be returned without review.

-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Advanced and innovative processing engineering and technologies that
    enhance food quality attributes, development, and application of
    analytical characterization techniques of physical, chemical,
    biological, and sensory natures.

2.  *This priority is shared among Programs 31.0 and 71.1.*
    Identification, processing, and tailoring of functional foods to
    promote energy balance, with an emphasis on efficacy and safety.
    Integrated projects should include a whole foods approach to
    developing functional foods that promote energy balance and optimal
    health.

    a.  Applicants integrating extension with other components should
        document evidence for stakeholder involvement in the development
        and implementation of the project.  Stakeholders may include
        consumers or representatives from industry.

    b.  Applicants are strongly encouraged to seek collaboration with
        industry.

    c.  Where applicable, use of populations at high risk for developing
        obesity in studies is strongly encouraged.

    d.  Projects should include expertise in multiple disciplines,
        including nutrition and food science.

    e.  Projects that incorporate interdisciplinary training of graduate
        students and postdoctoral researchers in nutrition, food
        science, and related disciplines are strongly encouraged.

**Other Key Information for Integrated Projects**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 5, 2007, by 5:00 P.M., Eastern Time**.
    Please use the formatting guidelines below. Format the letter with
    one inch margins and six lines per inch and font no smaller than 12
    point. The letter of intent must be submitted in portable document
    format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr. Ram
        Rao at <rrao@csrees.usda.gov> with the subject heading '*Letter
        of Intent Program 71.1_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **November 21, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

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-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

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-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

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-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

-   Collaboration with the industry is strongly encouraged. Where
    appropriate, involvement of the industry is required from concept to
    completion of the project.

```{=html}
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```
-   Improving Food Quality and Value program funds applications in the
    post-harvest area.

```{=html}
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```
-   Multi-disciplinary approaches are highly encouraged.

```{=html}
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```
-   Applications addressing combined and inseparable quality and safety
    objectives will be entertained in this program. However,
    applications dealing primarily with issues of food safety should
    consider submission to the Integrated Research, Education, and
    Extension Competitive Grants Program National Integrated Food Safety
    Initiative program
    (<http://www.csrees.usda.gov/funding/rfas/food_safety.html>).

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```
-   Applications that do not address at least one of the stated
    integrated program priorities will be returned without review.

```{=html}
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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

## Agroecosystems and Rural Prosperity Cluster Overview

The Agroecosystems and Rural Prosperity program cluster primarily
addresses CSREES' strategic goals to protect and enhance the Nation's
natural resource base and environment and to support increased economic
opportunities and improved quality of life in rural America. It also
supports CSREES' strategic goal of enhancing protection and safety of
the Nation's agriculture and food supply.

Agroecosystems are inherently complex, being composed of agricultural,
natural, and social systems. The fundamental concept behind this cluster
of programs is the application of ecological, economic, and sociological
principles to agricultural and community systems. The concept of
agroecosystems can be applied within agriculture, rangeland, forested,
or community systems at a range of spatial scales including the field,
family, the farm level enterprise, the landscape, watershed,
institution, or community. Agricultural and community systems, as
managed systems involving human interactions and use of inputs, are
influenced by and, in turn, influence the natural systems surrounding
them.

Human well-being is inextricably linked to the sustainable use and
management of agroecosystems. The fundamental purpose of agriculture is
to manage ecological structures, functions, and processes to favor human
needs. The concept of sustainable agroecosystem management allows for
achieving the traditional agricultural goal of production while
balancing the goals of conservation and protection of natural resources,
mitigation of environmental impacts, maintenance of ecosystem services,
and rural community viability. One benefit of the agroecological
approach is that it accommodates a broad range of performance criteria
in addition to increased production, such as ecological goods and
services, sustainability, food security, economic viability, resource
conservation, social equity, and community vitality. These criteria
provide focus for the various programs.

The overall goal of the Agroecosystems and Rural Prosperity program
cluster is to support research and integrated projects that will address
the design or function of productive agriculture and rural communities
that sustains yields and rural prosperity while minimizing the negative
environmental impacts of agricultural practices and technologies on
surrounding natural ecosystems. Addressing the degree to which
agriculture and rural communities are sustainable is a critically
important goal relevant to all USDA mission areas.

In FY 2008, the NRI invites applications in the following cluster of
programs related to Agroecosystems and Rural Prosperity:

> [23.1 Managed Ecosystems]{.underline}
>
> [25.0 Soil Processes]{.underline}
>
> [26.0 Water and Watersheds]{.underline}
>
> [27.0 Global and Climate Change]{.underline}
>
> [28.0 Air Quality]{.underline}
>
> [51.9 Biology of Weedy and Invasive Species in
> Agroecosystems]{.underline}
>
> [62.0 Rural Development]{.underline}
>
> [66.0 Agricultural Prosperity of Small and Medium-Sized
> Farms]{.underline}

## Agroecosystems and Rural Prosperity Program Descriptions

### 23.1 Managed Ecosystems

[National Program Leader]{.underline} − Dr. Diana Jerkins (202-401-6996
or <djerkins@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4 million, with
\$1.5 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budgets requests must not exceed
    \$500,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due October 9, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − December 19, 2007 (5:00 P.M., ET)

**Background**

The goals of the Managed Ecosystems program are to protect and enhance
the natural resource base and environment through the appropriate use
and management of agricultural ecological production systems; enhance
economic opportunities by increasing productivity and ecosystem
services; and improve the quality of life in rural America through
improved environmental quality.

To meet these identified needs of agriculture, the long-term (10-year)
goals for this program are: to develop, quantify, and verify predictive,
multifunctional agroecosystem management systems and conduct
experimental studies that will concurrently optimize resource use
efficiency while increasing product and environmental quality; and
develop indicators for land resource use assessment and quantify
agroecosystem changes. Over the long term, projects will involve the
design and verification of managed ecosystems, dissemination use of, and
education about innovative management strategies.

This program will take a systems approach. Systems research is
multidisciplinary and focuses on the interrelationship between
management practices and response to biological, physical, economic, and
social processes. A systems approach will be able to demonstrate
agricultural sustainability and identify points of sensitivity and
synergy between system components. Managed ecosystems that will be
designed and evaluated must be multi-functional (i.e. provide
agricultural product and other ecosystem services) and lead to increased
sustainability (system balance) over time.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Multifunctional agricultural production management systems --
    Create, quantify, and verify adaptive management systems that
    *concurrently* provide for both agricultural products (e.g. food,
    fiber, fuel), and other ecosystem services. Management
    recommendations must be multifunctional and lead to improved (1)
    productivity of multiple ecosystem services and (2) environmental
    quality of multiple, linked natural resource components. Systems are
    encouraged to include economic valuation of market and non-market
    ecosystem services. Models developed should be predictive to allow
    for changes in the system over time as system functions
    respond/adapt to management practices and external drivers.

2.  Monitoring systems quality -- Develop interdisciplinary approaches
    and processes to monitor agroecosystems to quantify improvements in
    production quality and environmental quality or ecosystem changes
    due to implementation of multifunctional management systems and
    strategies. Creation of monitoring technologies may be part of the
    monitoring process and should be verified as part of an applied
    research project. Creation of monitoring technologies exclusively
    will not be funded through this program, but should consider
    submission to the Small Business Innovation Research (SBIR)
    Competitive Grants Program.

**Other Key Information for Research Projects**

-   A letter of intent is required for **all** applications submitted to
    this program, including **standard research, strengthening,
    conference, and new investigator applications.** The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Please use the formatting guidelines below. Format the letter with
    one inch margins and six lines per inch and font no smaller than 12
    point. The letter of intent must be submitted in portable document
    format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Diana Jerkins (<djerkins@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 23.1_PD's Last Name*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
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```
-   Applications must address agricultural production systems.
    Development of management strategies should be limited to the
    following areas: 1) crop, 2) range/prairie, 3) forest, and 4)
    grazing and grassland. These systems may be at the rural level or
    urban agricultural interface. Animal systems may be incorporated as
    part of the listed four agriculture production systems. Projects may
    also have systems integration by combining systems, for example
    crop/range/livestock.

-   If the project involves model development, the model should
    conceptualize either new or improve existing models. The project
    must include field testing for verification of the model.

-   Specifically identify the types of ecosystem services being
    analyzed.

-   In order to better understand the interrelationship between
    agroecosystem functions, management systems being investigated must
    include multiple ecosystem services that are considered stacked or
    bundled.

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priority for Integrated Projects − Applicants must address the
following priority.**

1.  Development and use of multifunctional agricultural production
    management strategies (see description in managed ecosystem research
    priority 1) with emphasis on information dissemination and training
    on management methods, as well as development of curricula on
    systems research procedures and/or ecological systems functions.

**Other Key Information for Integrated Projects**

-   A letter of intent is required for this program**.** The letter of
    intent deadline is **October 9, 2007, by 5:00 P.M., Eastern Time**.
    Please use the formatting guidelines below. Format the letter with
    one inch margins and six lines per inch and font no smaller than 12
    point. The letter of intent must be submitted in portable document
    format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Diana Jerkins (<djerkins@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 23.1_PD's Last Name*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **October 19, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

```{=html}
<!-- -->
```
-   Extension and educational efforts should lead to the:

    -   Creation of strategies for the adoption of multifunctional
        agricultural production systems.

    -   Development of programs to train producers about the use and
        value of new systems and how ecosystems function.

    -   Incorporation of curriculum on systems management and ecosystem
        services in K-12 and/or university level education.

    -   Creation of methods for tracking the adoption rates of new
        systems by producers and educational outcomes of students.

    -   Offering of training and support to develop environmental
        stewardship skills and expertise as part of production
        management.

    -   Development of creative education and extension models to
        increase ecological and sustainable agriculture literacy and
        adoption within the university, agricultural, and larger
        communities.

```{=html}
<!-- -->
```
-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
<!-- -->
```
-   If the integrated project involves education, the approach should
    utilize integrative, multidisciplinary managed ecosystem thematic
    areas for: curricula design, development, and implementation; the
    identified degree level (i.e. baccalaureate, masters, or doctoral);
    and/or experiential learning opportunities for undergraduate
    programs or provide a cutting edge scientific research environment
    for graduate level training. For additional support of educational
    opportunities refer to the Higher Education Challenge Grants
    Program, Higher Education Multicultural Scholars Program, or Food
    and Agricultural Sciences National Needs Graduate and Postgraduate
    Fellowship Grants Program funding opportunities. To learn more about
    these programs, visit the website
    <http://www.csrees.usda.gov/fo/funding.cfm>.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 25.0 Soil Processes 

[National Program Leader]{.underline} − Dr. Nancy Cavallaro
(202-401-4082 or <ncavallaro@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.0 million

[Proposed Budget Requests]{.underline} −

-   Proposed research budget requests must not exceed \$400,000 for
    multi-institution for project period of 2-4 years (including
    indirect costs).

-   Proposed research budget requests must not exceed \$325,000 for a
    single institution for project period of 2-4 years (including
    indirect costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due November 19, 2007 (5:00 P.M., ET);
see the **Other Key Information** section for format and submission
instructions.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

Soil is a vital natural resource that not only sustains plant and animal
productivity, but also has profound effects on the health and quality of
the environment. As such, agriculturally-related sustainability hinges
on the interactions among the biological, chemical, and physical
properties and processes in this below-ground ecosystem. Research is
needed to fill knowledge gaps regarding interactions of the many dynamic
soil properties and processes affecting soil quality as it relates to
agricultural sustainability and agroecosystem goods and services in
order to better manage this critical resource.

Soils play an important role in ecosystem scale processes and
biogeochemical cycles at the catchment to regional scales, but it is
critical to recognize the spatial and temporal variability of soil
properties and processes, many of which occur only at microsites within
the soil. These small-scale interfaces are of central importance to
understanding the soil's role in many larger scale biogeochemical cycles
and to improving soil management in field, plot, and farm. Soil
scientists have the opportunity to significantly improve our
understanding of the role soil plays in large scale environmental
processes through utilization of ground-based observations and remotely
sensed spatial data in concert with advanced tools to analyze
microsite-, as well as meso-scale processes in these complex systems.

Science-based knowledge is needed that leads to the clarification and
understanding of the interactions among soil physical, chemical, and
biological processes, their responses to changing conditions, and their
impact on agroecosystems. Understanding these complex interactions
related to isolated, as well as coupled processes requires an
interdisciplinary approach that recognizes the unique matrix of the soil
in place. Ultimately, this approach should lead to the development of
practical tools, strategies, and predictive models that enhance
sustainable agricultural productivity at the farm level, while avoiding
or ameliorating detrimental effects on natural resources and
environmental health.

The long-term goal (10-year) for this program is to generate
science-based knowledge that will lead to the development, adoption, and
implementation of practices and tools that will ensure improved soil
health and productivity. This means reduced contamination and increased
efficiency of resource management and agricultural production, while
maintaining soil and ecosystem health. It also will require improved
predictive and conceptual models of dynamic soil properties and soil
change for reducing negative impacts and feedbacks under changing
conditions. Improving soil quality and health will increase productivity
and enhance sustainability while protecting and enhancing the Nation's
natural resources and environment.

**FY2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Interdisciplinary studies involving the interrelationships among
    soil physical, chemical, and biological characteristics and
    processes related to soil quality and sustainability, especially
    regarding water and nutrients in relation to agricultural quality,
    productivity, and environmental health.

2.  Multi-scale research that can help bridge the gap between molecular
    and microscopic site process studies and field landscape and/or
    watershed-scale studies relating to soil quality.

3.  Development and/or application of new or improved technologies,
    methodologies, tools, or strategies to enhance our understanding of
    biological, biogeochemical, and physical processes. In addition,
    these methods or tools should be used to enhance our understanding
    of dynamic properties in soils related to agricultural production,
    as well as soil and environmental health, focusing specifically on
    water, carbon, and nutrient cycles at multiple scales where
    appropriate.

**Other Key Information**

-   A letter of intent is required for this program. The letter of
    intent deadline is **November 19, 2007, by 5:00 P.M., Eastern
    Time**. Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

    ```{=html}
    <!-- -->
    ```
    -   On Page 1 include a cover letter with the following information:

    ```{=html}
    <!-- -->
    ```
    -   the name of the lead project director;

    -   the names of collaborating investigators; and

    -   the program priority addressed by the project.

        -   On Page 2 include

```{=html}
<!-- -->
```
-   a descriptive title; and

-   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Nancy Cavallaro (<ncavallaro@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 25.0_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 3, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel.

    -   Multi-disciplinary approaches are encouraged; projects
        addressing priorities 1 and 2 [must]{.underline} be
        interdisciplinary.

    ```{=html}
    <!-- -->
    ```
    -   Applicants must articulate the relevance of their research to
        agriculture, range, and/or forestry.

1.  -   Proposed projects should be interdisciplinary and address
        relevant biotic and abiotic factors and processes. Projects may
        be fundamental or applied, but must address physical, chemical,
        and biological aspects from a point of view of the soil in situ.

    -   Model systems are appropriate, but must articulate steps needed
        to validate interpretations for application to the field.

    -   Fate and transport of selected pathogens will be addressed in
        the Water and Watersheds program (26.0). Applications addressing
        water quality combined with extension and education components
        should consider submission to the CSREES Integrated Research,
        Education, and Extension Competitive Grants Program National
        Integrated Water Quality program
        (<http://www.csrees.usda.gov/funding/rfas/water_quality.html>).

    -   Applications addressing soil insect and arthropod pests or
        soil-borne plant pathogens should consider submission to the
        CSREES Integrated Research, Education, and Extension program in
        Pest Management. From the Funding Ops Web page
        ([www.csrees.usda.gov/fo/funding.cfm](http://www.csrees.usda.gov/fo/funding.cfm))
        select 'Pest Management from the Emphasis Area pull down box and
        'Integrated Programs' from the Program Group pull down box.

    -   Applications addressing interactions of plants and soil microbes
        should focus on the soil process. Interdisciplinary rhizosphere
        process studies are appropriate to this program, while studies
        focused on plant-microbe interactions or root processes within
        the plants and removed from the influence of the soil, should
        consider the Microbial Biology (51.8) or Plant Biology (56.0)
        programs.

        -   Applications that do not address at least one of the stated
            research program priorities will be returned without review.

-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 26.0 Water and Watersheds

[National Program Leader]{.underline} − Ms. Mary Ann Rozum (202-401-4533
or <mrozum@csrees.usda.gov>[)]{.underline}

[Total Program Funds]{.underline} − approximately \$5.3 million

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

```{=html}
<!-- -->
```
-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − January 17, 2008 (5:00 P.M., ET)

**Background**

The goals of the Water and Watersheds program are to protect and enhance
the natural resource base and environment by improving and maintaining
healthy watershed habitat and water supply protection; improve the
quality of life in rural America through adequate clean water supplies;
and protect food safety through clean irrigation and livestock drinking
water supplies.

The long-term (10-year) goals for this program are: reduce pathogens,
such as bacteria, viruses, and protozoa in waters derived from
agricultural and rural watersheds, as well as maintain adequate water
supplies for agricultural crop and livestock production and rural use.

**FY 2008 Priorities for Research Projects − Applicants must address at
least one of the following priorities.**

1.  Understand the sources, fate, and transport of pathogens, such as
    bacteria, protozoa, and viruses in soil, surface and ground water,
    and irrigation systems of agricultural and rural watersheds to
    reduce zoonotic pathogens in the environment. Special emphasis is
    considered for *Escherichia coli*, Cryptosporidium, and enteric
    viruses.

2.  Identify, evaluate, and understand producer management behaviors
    that improve agricultural water conservation in crop, livestock, and
    poultry production, with an emphasis on a) projects that integrate
    hydrologic, economic, and policy components; b) social determinants
    of water use; and c) documented water savings, especially at spatial
    scales greater than a single field.

**Other Key Information**

-   Applications addressing integrated research, extension, and
    education for water resources should consider submission to the
    CSREES Integrated Research, Education, and Extension Competitive
    Grants Program National Integrated Water Quality program
    (<http://www.csrees.usda.gov/funding/rfas/water_quality.html>).

    -   Applications that do not address at least one of the stated
        research program priorities will be returned without review.

```{=html}
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```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 27.0 Global and Climate Change

[National Program Leaders]{.underline} --

Dr. Nancy Cavallaro (202-401-4028 or <ncavallaro@csrees.usda.gov>)

Dr. Louie Tupas (202-401-4926 or <ltupas@csrees.usda.gov>)

[Total Program funds]{.underline} -- approximately \$1 million per year

[Proposed budget requests]{.underline}-

-   Proposed budget requests for both research and integrated projects
    are expected to range between \$300,000 and \$600,000 for project
    period of 2-3 years (including indirect costs).

[Letter of intent]{.underline} -- Not required for this program.

[Application Deadline]{.underline} -- For FY 2006-2008 funds, this
program element is in partnership with the Environmental Protection
Agency (EPA) for the priority involving land use change and invasive
species, and with the National Aeronautics and Space Administration
(NASA) for Carbon Cycle Science priority. Please note that proposals
submitted for review for these two themes in this program element must
be submitted through EPA or NASA, for the two respective priorities, in
accordance with submission instructions outlined in separate program
solicitations. The program deadlines were in June, 2007.

**Background**

The sustainability of agriculture, forest and rangelands depends on
understanding the factors that influence climate change, the mechanisms
that may enhance or mitigate this change, and its effects on food and
fiber production and natural resources. Program priorities are drawn
primarily from the US Climate Change Strategic Plan
(<http://www.climatescience.gov/Library/stratplan2003/default.htm>), and
include human dimensions of these issues. Past solicitations have
included priorities in the areas of carbon cycle science, land use and
land cover change, and invasive species. Within the U.S. Climate Change
Science Program (CCSP), CSREES participates in interagency working
groups on Carbon Cycle, Water Cycle, Ecosystems, and Land Use and Land
Cover Change.

### 28.0 Air Quality

[National Program Leader]{.underline} − Dr. Ray Knighton (202-401-6417
or <rknighton@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5 million, with
approximately \$3 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$600,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due March 5, 2008 (5:00 P.M., ET) for
**integrated projects**; see the **Other Key Information** section for
format and submission instructions.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

Agriculture, forest, and range production practices have increasingly
become subject to state and federal regulations aimed at protecting air
resources. In many instances, data do not exist or are not
representative of agricultural industries for the purpose of estimating
emissions to the atmosphere of regulated pollutants and greenhouse
gases, other than carbon dioxide, from agriculture, as well as public
nuisances, such as odors and fugitive dust. In addition, there is a need
to develop practices and technologies to assist producers in preventing
or mitigating air emissions.

The long-term (10 year) goals of this program are: 1) to develop
emission data for agriculture, forest, and range production practices
leading to science-based emission reduction targets to improve air
quality and protect human and environmental health; 2) to develop
effective mitigation strategies and increase adoption of best management
practices to reduce agricultural emissions; and 3) to improve
understanding of the measurement, production, flux, and fate and
transport of odor, gases, and particulate matter (PM) leading to
knowledge of the environmental fate of agricultural atmospheric
emissions.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Measurement and Monitoring Integrated projects are solicited to
    improve measurement protocols/instrumentation and remote sensing to
    measure and characterize particulate matter and gases for within
    field/facility and edge-of-field/facility boundaries. Emission data
    for particulates, odors, and gases is of primary concern and is
    needed for all aspects of production practices and naturally
    occurring events such as wind and wet/dry deposition to update
    existing inventories. Projects are especially encouraged that focus
    on crop production practices. High priority emission sources and
    corresponding constituents are: 

    a.  tillage, nutrient management, and pest management, practices
        that emit PM, ammonia, nitrous oxide, and highly reactive
        volatile organic compounds (VOCs).

    b.  crop harvest and post-harvest practices that emit PM and gases.

    c.  controlled burning practices as sources of PM, gases, and smoke.

    d.  animal feeding operations as sources of ammonia, PM, VOCs,
        hydrogen sulfide, methane, odor and odorants.

> For projects addressing emissions from animal feeding operations,
> measurement and monitoring projects that complement and do not
> duplicate the National Air Emissions Monitoring Study (NAEMS) are
> encouraged. Projects that include the same animal species, production
> practices, geographic regions, and analytes currently in the NAEMS
> study will not be considered for funding.
>
> The characterization of the physical, chemical, and biological nature
> of aerosols from agriculture, range, and forest sources is needed.
> Projects should identify whether they will address fine particulate
> matter\
> (\< 2.5 μm in diameter) or coarse particulate matter (2.5 to 10 μm in
> diameter). Methods to determine the scale-dependence of spatial and
> temporal processes and the accuracy of techniques for monitoring and
> characterizing agriculturally important gases, odors, odorants, and
> aerosols are also requested.

2.  Fate and Transport Integrated projects should examine the fate and
    transport of emitted particulates and gases with specific emphasis
    placed on ammonia and nitrous oxide. Improved models are needed to
    predict movement and dispersion of air pollutants from production
    practices and management operations. Process-based mechanistic
    models using mass balance techniques for component processes of the
    whole enterprise are of specific interest. Projects to better
    understand the processes controlling wet and dry deposition of
    reactive nitrogen compounds from agricultural sources are solicited.

3.  Mitigation Integrated projects should examine the efficacy of new
    and existing methods for mitigating emissions of nitrogen and other
    agricultural air pollutants to the atmosphere and the development of
    best management practices. Projects are especially encouraged that
    evaluate the efficacy of conservation practices and other control
    technologies to reduce particulate and gaseous emissions. To ensure
    the relevance and adoption of practices, these projects should also
    analyze economic, behavioral, cultural, or policy barriers to
    implementing practices that reduce emissions. Evidence of
    commensurate investigator expertise to address and evaluate the
    human dimensions of the above mentioned barriers is required.

**Other Key Information for Integrated Projects**

-   A letter of intent is **required** for **integrated projects** in
    this program. The letter of intent deadline is **March 5, 2008, by
    5:00 P.M., Eastern Time**. Format the letter of intent using the
    criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

        -   The letter of intent is limited to two pages.

        ```{=html}
        <!-- -->
        ```
        -   On Page 1 include a cover letter with the following
            information:

    ```{=html}
    <!-- -->
    ```
    -   the name of the lead project director;

    -   the names of collaborating investigators; and

    -   the program priority addressed by the project.

        -   On Page 2 include

```{=html}
<!-- -->
```
-   a descriptive title; and

    -   a brief statement of **integrated** objectives and approaches;

    -   list stakeholders/audience and their involvement in the project;

    -   a brief statement of the project management plan including
        stakeholder interactions;

    -   anticipated outcomes and impacts;

    -   a brief statement of performance metrics; and

    -   a brief statement of your project evaluation plan.

        -   Attach the PDF letter of intent to an email addressed to Dr.
            Ray Knighton (<rknighton@csrees.usda.gov>) with the subject
            heading\
            '*Letter of Intent Program 28.0_PD's Last Name'*.

        -   An acknowledgement receipt will be sent indicating the
            letter was received.

        -   A letter of intent is not required for conference grant
            proposals, career enhancement grant proposals, equipment
            grant proposals, and seed grant proposals.

        -   Letters of intent will be reviewed relative to suitability,
            scope, and needs of the program as delineated in the program
            description and priorities.

        -   Submission of more than one letter of intent is discouraged.

        -   Project Directors will receive a response from the National
            Program Leader inviting or rejecting a full application by
            **March 19, 2008**. The National Program Leader will not
            provide feedback regarding content in the letter.

        -   Only invited full applications will be reviewed by the
            panel.

```{=html}
<!-- -->
```
-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    component area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

    -   Applications that do not address at least one of the stated
        integrated or research program priorities will be returned
        without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

**FY 2008 Priorities for Research − Applicants must address at least one
of the following priorities.**

1.  Characterizing particulate matter and gases and techniques for
    monitoring and characterizing emissions as outlined in priority 1
    under integrated projects.

2.  Fate and transport as outlined in priority 2 under integrated
    projects.

**Other Key Information for Research Projects**

-   Applications that do not address at least one of the stated
    integrated or research program priorities will be returned without
    review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 51.9 Biology of Weedy and Invasive Species in Agroecosystems

[National Program Leader]{.underline} − Dr. Michael Bowers (202-401-4510
or <mbowers@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$4.6 million, with
\$2.0 million for integrated projects

[Proposed Budget Requests]{.underline} −

-   Proposed research project budget requests must not exceed \$400,000
    for project period of 2-4 years (including indirect costs).

-   Proposed integrated project budget requests must not exceed
    \$500,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Due **December 6, 2007 (5:00 P.M.,
ET);** see the **Other Key Information** section for format and
submission instructions.

[Application Deadline]{.underline} − March 5, 2008 (5:00P.M., ET)

**Background**

It has been estimated that approximately 50,000 species of plants and
animals have been introduced into the

United States resulting in more than \$100 billion in losses and damage
each year. Invasive species threaten biodiversity, habitat quality, and
ecosystem function. It is estimated that invasive species have
contributed to the decline of 42 percent of the endangered and
threatened species in the United States. The National Research Council
in its report, *Grand Challenges in Environmental Sciences***,** cited
the critical importance of addressing invasive species issues[^3].
Non-indigenous weeds alone cost U.S. agriculture \$7-27 billion per
year. Exotic, invasive species are a particularly prevalent feature of
agroecosystems and a major threat to food and fiber production. The
Council for Agricultural Science and Technology has emphasized the
escalating risk of invasive species to agricultural systems[^4].
Increased globalization and climate change will likely increase the
introduction, spread, and impact of invasive species.

The long-term (10-year) goal of the program is to provide ecologically
and economically rational strategies for management, control, or
elimination of weedy or invasive species.

**FY 2008 Priority for Research** **Projects − Applicants must address
the following priority.**

1.  Research that establishes mechanisms determining the abundance and
    distribution of weedy and invasive species and the individual or
    collective impact of these species on agroecosystem functionality.
    Proposed research might investigate how different cultivation and
    nutrient management regimes/practices, past and current land use, or
    disturbance, including fire, pests, and grazing, affects the
    abundance of weedy and invasive species and how these species, in
    turn, impact the conditions and processes through which
    agroecosystems provide food, fuel, fiber, and fresh water or by
    regulating air quality, climate, erosion control, and human
    diseases. Research that provides an economic accounting of such
    impacts is encouraged but not required in FY 2008.

**FY 2008 Priorities for Integrated Projects − Applicants must address
the following priority.**

1.  Development, delivery, and implementation of ecologically-based,
    invasive species management programs (e.g. use of cover crops,
    grazing, tillage, and biocontrol agents) that includes economic
    decision support tools to evaluate tradeoffs of different management
    strategies.

**Other Key Information for Research and Integrated Projects**

-   A letter of intent is required for this program. The letter of
    intent deadline is **December 6, 2007 by 5:00 P.M., Eastern Time**.
    Format the letter of intent using the criteria below.

    -   Format the letter with one inch margins and six lines per inch
        and font no smaller than 12 point. The letter of intent must be
        submitted in portable document format (PDF).

    -   The letter of intent is limited to two pages.

        -   On Page 1 include a cover letter with the following
            information:

            -   the name of the lead project director;

            -   the names of collaborating investigators; and

            -   the program priority addressed by the project.

        -   On Page 2 include

            -   a descriptive title; and

            -   a brief statement of approaches and objectives

    -   Attach the PDF letter of intent to an email addressed to Dr.
        Michael Bowers (<mbowers@csrees.usda.gov>) with the subject
        heading\
        '*Letter of Intent Program 51.9_PD's Last Name'*.

    -   An acknowledgement receipt will be sent indicating the letter
        was received.

    -   A letter of intent is not required for conference grant
        proposals, career enhancement grant proposals, equipment grant
        proposals, and seed grant proposals.

    -   Letters of intent will be reviewed relative to suitability,
        scope, and needs of the program as delineated in the program
        description and priorities.

    -   Submission of more than one letter of intent is discouraged.

    -   Project Directors will receive a response from the National
        Program Leader inviting or rejecting a full application by
        **December 20, 2007**. The National Program Leader will not
        provide feedback regarding content in the letter.

    -   Only invited full applications will be reviewed by the panel

```{=html}
<!-- -->
```
-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
<!-- -->
```
-   The program will consider projects (research and integrated) that
    focus on the biology of weedy and invasive plant and animal species
    of economic importance to agriculture. Currently, the program does
    not support research on pathogenic organisms. The projects proposed
    should have direct and obvious relevance to the elimination,
    management, or control of invasive species in agroecosystems,
    including cropping systems, managed forests, or rangeland.
    Successful applications will establish links between fundamental
    biological or ecological relationships and invasive species
    management plans and strategies. Research that proposes to combine
    organismal biology (genomics, physiology, and cell biology) with
    ecological processes is encouraged. Collaborative teams of land
    managers, economists, weed biologists, soil scientists, population
    biologists, ecologists, physiologists, biogeochemists, and wildlife
    managers or those with expertise in simulation modeling and GIS are
    encouraged to apply. Applications that do not meet the above
    criteria or do not match the priority areas will be returned without
    review.

-   **New Project Opportunity: REE NET -** Beginning in FY 2008 NRI
    Program 51.9 will accept research and integrated proposals that
    coordinate networking activities around either the research or
    integrated program priority. These projects should move the field
    forward or create new research directions or opportunities through
    increased coordination, networking and synthesis. Moreover, these
    projects should: foster communication and promote collaboration
    among Research, Education, and Extension (REE) faculty with common
    interests across disciplinary, geographical, and organizational
    boundaries; establish networks and collaborations between faculty at
    Tier 1and 2 intuitions, and faculty at small, mid-size, and minority
    serving institutions (1890s, HSI, 1994); minimize isolation and
    maximize cooperation so as to eliminate unnecessary duplication of
    efforts; and coordinate the development of new tools and methods and
    generate community resources such as databases. Additional
    considerations include:

    -   The size of a group/network will vary depending on the theme and
        needs of the proposed activity and may be regional, national, or
        international in scope.

    -   Each network will include a diversity of members---from
        established researchers at tier 1 and 2 schools to new
        researchers, post-docs, graduate students, and faculty at small,
        mid-size, and minority serving institutions (1890s, HSI, 1994s).

    -   Each project will include clearly define management plan that
        includes a description of the specific roles and
        responsibilities of the PD/Coordinator and other members of the
        group/network. The management plan should include provisions for
        flexibility to allow the structure of the group to change over
        time as membership and the network\'s foci evolve.

    -   Awards are expected to be no more than \$50,000/yr for three or
        four years. Although REE-Net activities are expected to involve
        investigators from multiple sites, a single organization must
        serve as the submitting organization for each proposal. When the
        proposed activity involves generation of community resources
        such as databases, a plan for their timely release and the
        mechanism of sharing must be in-place. In addition, there must
        be a plan for the long-term maintenance of such resources. The
        application must state in the first sentence in the summary that
        the project is a REE-Net proposal.

        -   Applications that do not address at least one of the stated
            integrated or research program priorities will be returned
            without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 62.0 Rural Development

[National Program Leader]{.underline} − Dr. S. (Suresh) Sureshwaran
(202-720-7536 or <ssureshwaran@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$ 5.1 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed
    \$500,000 for project period of 2-4 years (including indirect
    costs).

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − February 14, 2008 (5:00 P.M., ET)

**Background**

During the last 30 years, dramatic social, economic, and technological
changes have occurred in many rural areas in the United States. Although
farming continues to be an important source of income, most of rural
America is moving from agrarian to post-agrarian economies. Some
communities are facing economic decline and rural exodus, while other
regions, especially coastal and mountainous areas, have experienced
increased economic growth and new resident influx. However, these
changes have not benefited all rural people.

Despite decades of intervention and billions of dollars in public
investment, many rural residents have a lower quality of life than many
urban residents. Economic development and employment have been hampered
by the lack of trained workforce, entrepreneurship skills, public
services, and sufficient market size for the provision of some goods and
services. Rural poverty remains as one of the most difficult social
problems facing legislators and other public policy makers. Some
industrial development strategies have adversely affected the
environment and the long term sustainability of viable economic
development. In addition, population gain driven by migration has
increased diversity. The influx of migrant labor and senior citizens, as
well as the exodus of educated youth may have exacerbated the economic
vitality and increased poverty in some rural communities.

To meet these identified problems and opportunities of rural
development, the long-term (10 year) goals for this program is to help
develop sustainable rural communities through integrated projects
focused on: 1) enhancing economic vitality of rural communities and, in
turn, reduce rural poverty; 2) protecting and enhancing economic growth
and the natural resource base of rural areas by developing strategies
that reduce the competition between economic growth and the environment;
and 3) building a diversified workforce to meet the needs of the present
and for the future.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Enhance knowledge, evaluate policy options, and implement practical
    strategies to create employment opportunities and income growth,
    including appropriate entrepreneurship and small business
    development strategies.

2.  Estimate the costs, benefits, and societal impacts of protecting the
    environment, using market and non market techniques, and implement
    practical strategies to enhance ecosystem services while promoting
    economic development and employment growth.

3.  Enhance understanding of and develop innovative strategies to build
    the rural workforce for the present and for the future, including
    projects to attract and retain rural youth.

**Other Key Information**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
<!-- -->
```
-   Integrated projects that identify and recruit undergraduate students
    for pipelining into graduate programs in rural development or
    related disciplines are particularly encouraged. Such training and
    experiential learning component must go beyond the level of
    laboratory or other data collection and analysis projects. Examples
    of education projects include curriculum and/or degree program
    development in rural development,
    multi-college/university/department approaches to mentoring and
    experiential learning in rural development, faculty sharing, and
    joint degrees. The education component is expected to describe
    institutional resources and must clearly indicate how and why the
    proposed new curriculum or degree will complement, enhance, or
    replace any existing curriculum or programs at the institution and
    help promote rural development. Projects should also include plans
    for assessment and performance outcome measurement for continuation
    or expansion beyond the period of USDA support and potentially for
    tracking of participant accomplishments after course completion.

```{=html}
<!-- -->
```
-   Interdisciplinary applications focused on the creation of
    sustainable rural communities by protecting the environment,
    reducing poverty, and enhancing community economic vitality are
    strongly encouraged.

-   Applications that focus on small and medium-sized farms and not
    directly related to the larger rural community should be directed to
    the Agricultural Prosperity for Small and Medium-Sized Farms (66.0)
    program. Applications not focused on rural community development
    should not be directed to this program.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

### 66.0 Agricultural Prosperity for Small and Medium-Sized Farms

[National Program Leader]{.underline} −

Dr. S. (Suresh) Sureshwaran (202-720-7536 or
<ssureshwaran@csrees.usda.gov>)

Dr. Diana Jerkins (202-401-6996 or <djerkins@csrees.usda.gov>)

[Total Program Funds]{.underline} − approximately \$5 million

[Proposed Budget Requests]{.underline} −

-   Proposed integrated project budget requests must not exceed
    \$500,000 for project period of 2-4 years (including indirect
    costs).

-   Proposed budget requests over \$400,000 are expected to be
    multi-investigator and/or multi-institutional.

-   Requests exceeding the budgetary guidelines above will be returned
    without review.

[Letter of Intent]{.underline} − Not required for this program.

[Application Deadline]{.underline} − June 5, 2008 (5:00 P.M., ET)

**Background**

Small and medium-sized farms are challenged by limited economic
opportunities and increasing concerns about environmental quality, as
indicated by their low value of agricultural products sold, decreasing
share of the food dollar, and the perceived trade-off between
agricultural sustainability and economic viability. In recent years,
these challenges have been magnified by changes in market conditions
caused by tremendous demographic shifts, new global markets and vertical
integration, and the increasing competition for farm land for
non-agricultural uses. Therefore, the purpose of this program is to
foster interdisciplinary projects that enhance interactions between the
economic and environmental components important to the long-term
viability, competitiveness and efficiency of small and medium-sized
farms (including social, biological and other components, if necessary).
These include small and medium-sized dairy, livestock, forestry, crop
and other commodity operations. While small and medium-sized farms with
less than \$500,000 in annual sales account for less than 25 percent of
the value of all agricultural products sold in the U.S., the long-term
viability of these farms is critical to the prosperity of rural people
and places as these farms account for approximately 92 percent of all
farms in the U.S. Therefore, the program will also foster
interdisciplinary studies to enhance income accruing to small and
medium-sized farms through value-added activities and in turn, their
contribution to rural prosperity.

To meet these identified needs of agriculture, the long-term (10 year)
goals for this program are: increase the value of agricultural products
sold per farm by small and medium-sized farms through the adoption of
environmentally sustainable, economically viable best management
practices; increase the share of the food dollar accruing to the small
and medium-sized farms and to rural communities by creating on-farm
value added activities based on enhanced knowledge of the interactions
between changing consumer needs, environmental sustainability and
economic profitability; and adopt ecological practices that will enhance
the economic value of the land, operated by small and medium-sized
farms, in agricultural use.

**FY 2008 Priorities for Integrated Projects − Applicants must address
at least one of the following priorities.**

1.  Increasing the productivity and profitability of new and existing
    small and medium sized farms and ranches through education and
    extension programs based on new knowledge generated by research on
    factors that advance the economic and environmental integration of
    on-farm agricultural production and soil and water conservation
    practices.

2.  Identification and dissemination of information to enhance the net
    economic, environmental and social benefits to small and
    medium-sized farms of on- and off-farm agricultural business
    activities, including impacts of innovative marketing and regional
    food systems, off-farm employment, migrant labor, etc.

3.  Through innovative, research-based education and/or extension
    programs, enhance the understanding of students, current and future
    policymakers, farmers and others on how land use change, farm
    transition, and farm entry issues affect the prosperity of small and
    medium-sized farms, the ecosystem, and rural prosperity. 

**Other Key Information**

-   Integrated project proposals must include at least two of the three
    components of the agricultural knowledge system (i.e., research,
    education, and/or extension) with each component represented by one
    or more objectives within the proposal. Projects must budget
    sufficient resources to carry out the proposed set of extension,
    education, and/or research activities, with **no more than
    two-thirds** of a project's budget being allocated to a single
    knowledge area. Please see Part II.C.3 for a full listing of
    integrated project requirements, which should be followed closely to
    ensure success in the peer review process.

-   Please see Part V, B for the criteria that will be used to evaluate
    integrated proposals. Applicants are also encouraged to see
    [http://www.csrees.usda.gov/funding/integrated/integrated](http://www.csrees.usda.gov/funding/integrated/integrated.html)
    for an example of an integrated proposal and other grant-writing
    resources.

```{=html}
<!-- -->
```
-   Applications for integrated projects must include the elements of a
    logic model detailing the activities, outputs, and outcomes of the
    proposed project. This information may be provided as a narrative or
    formatted into a logic model chart. The logic model planning process
    is a tool that should be used to develop your project **before**
    writing your proposal. Two additional pages are allowed for this
    information. See Part IV.B.1c(10) for details on where to attach
    this information to your application. More information and resources
    related to the logic model planning process are provided at
    <http://www.csrees.usda.gov/funding/integrated/integrated_logic_model.html>.

```{=html}
<!-- -->
```
-   The NRI encourages integrated projects that develop content suitable
    for delivery through eXtension. This content is for "end users" as
    opposed to staff development and must align with the eXtension
    Guiding Principles, Implementation Plan and other requirements as
    presented at
    [http://about.extension.org/university-researcher/](http://about.extension.org/).
    Funds may be used to contribute to an existing Community of Practice
    or to form a new Community of Practice as appropriate.

```{=html}
<!-- -->
```
-   The Agricultural Prosperity for Small and Medium-Sized Farms program
    encourages projects that enhance graduate student interactions with
    teachers in K-12 schools to share their research findings, improve
    communication and team building skills, enhance curriculum for and
    enrich learning and interest in agricultural science education among
    K-12 students (including social sciences), and help strengthen
    partnerships between institutions of higher education and local
    school districts. Examples of such projects can be found through
    NSF's GK-12 program at:
    <http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5472&org=NSF>

```{=html}
<!-- -->
```
-   Applications should be interdisciplinary and focused on the economic
    profitability and the environmental sustainability of small and
    medium-sized farms.

-   Applications that focus on community development activities not
    directly related to agriculture should be directed to the Rural
    Development (62.0) Program. Applications not focused on the
    profitability and viability of small and medium-sized farms should
    not be directed to this program.

    -   Applications that do not address at least one of the stated
        integrated program priorities will be returned without review.

```{=html}
<!-- -->
```
-   If a project is funded, beginning in the first year of funding, the
    project director will be required to attend annual investigator
    meetings. Reasonable travel expenses should be included as part of
    the project budget.

#  

# PART III---ELIGIBILITY INFORMATION 

# 

## A. Eligible Applicants 

For **research projects**, the eligibility requirements for the NRI are
as follows: except where otherwise prohibited by law, State agricultural
experiment stations, all colleges and universities, other research
institutions and organizations, Federal agencies, national laboratories,
private organizations or corporations, and individuals are eligible to
apply for and to receive a competitive grant. The Agricultural Research
Enhancement Awards (AREA) have some notable differences in eligibility
from these requirements. See Part II C, 2 for details.

For **integrated projects**, the eligibility requirements for the NRI
are as follows: except where otherwise prohibited by law, State
agricultural experiment stations, all colleges and universities,
research foundations maintained by colleges or universities, private
research organizations with established and demonstrated capacities to
perform research or technology transfer, Federal research agencies, and
national laboratories are eligible to apply for and receive a
competitive grant. The bridge grants have some notable differences in
eligibility from these requirements. See Part II, C, 3(b) for details.

Applicants must respond to the program priorities and deadlines found in
the FY 2008 RFA. Applications from scientists at non-United States
organizations will not be accepted. Award recipients may subcontract to
organizations not eligible to apply provided such organizations are
necessary for the conduct of the project.

## 

## B. Request for Determination 

If an applicant's institution can be considered a minority-serving
institution and wishes to be considered for a bridge grant (as described
in Part II, C, 3(b)), but does not work with one or more of the minority
groups criteria specified in the Definitions section of this RFA (see
Part VIII, H), the applicant must submit to CSREES documentation
supporting the request. This documentation must be submitted as part of
the requestor's application package and must be received by CSREES by
the applicable program deadline. The Secretary of Agriculture or
designated individual will determine whether the group or groups
identified are eligible under this program.

The Request for Determination may be submitted as a PDF attachment in
Field 11 in the Other Attachments portion of the R&R Other Project
Information Form. In addition, the following information must be
provided in the order specified below:

> \(a\) A description of each minority group that is being submitted for
> determination;
>
> \(b\) Data or studies supporting this group's designation as a
> minority group; and
>
> \(c\) Data indicating that enrollment of the minority group(s) exceeds
> 50 percent of the total enrollment at the academic institution,
> including graduate and undergraduate and full- and part-time students.

## 

## C. Cost Sharing or Matching 

For research projects, unless otherwise indicated, cost sharing or
matching is not required for NRI awards. See Part II, C, 2, (c), (ii)
for matching requirements for equipment grants.

For integrated projects, if a grant is for applied research that is
commodity-specific and not of national scope, the grant recipient is
required to match the USDA funds awarded on a dollar-for-dollar basis
from non-Federal sources with cash and/or in-kind contributions.

# PART IV---APPLICATION AND SUBMISSION INFORMATION

## A. Electronic Application Package 

Applications to NRI programs must be submitted electronically through
Grants.gov in response to this RFA.

Prior to assembling an application to the NRI, first contact the
organization's **Authorized Organizational Representative (AOR)** to
confirm the organization is prepared to submit applications through
Grants.gov. See <http://www.grants.gov/GetStarted> for steps on
registering with Grants.gov.

The NRI electronic application package may be accessed through the NRI
Funding Opportunity page on the CSREES Web site or the Grants.gov Web
site. To access the application package through the NRI Funding
Opportunity Web page, go to <http://www.csrees.usda.gov/fo/nri>. Locate
the table at the bottom of the page and select the live link associated
with "Funding Opportunity Number". To access the application package via
Grants.gov, go to [http://www.grants.gov](http://www.grants.gov/).
Select the "[Apply for
Grants](http://www.grants.gov/applicants/apply_for_grants.jsp)" link on
the left-hand side of page. Selecting "Step 1: [Download a Grant
Application Package](https://apply.grants.gov/forms_apps_idx.html),"
enter the CFDA number 10.206 and select "Download Package." From the
search results, select "download" to access the instructions and
application. **Grants.gov does not currently support the Windows Vista
operating system. The PureEdge software used by Grants.gov for forms may
not be compatible with MS Vista.**

The electronic application package contains the "[CSREES Grants.gov
Application Guide: A Guide for Preparation and Submission of CSREES
Applications via
Grants.gov](http://www.csrees.usda.gov/funding/grant_forms/electronic_app_guide.pdf)."
**This guide contains an introduction and general Grants.gov
instructions, information about how to use a Grant Application Package
in Grants.gov, and instructions on how to complete the application
forms.** If electronic assistance is needed, refer to Part III sections
7.1 and 7.2 for contact information. **Please note, if the application
instructions in this RFA differ from those in the CSREES Grants.gov
Application Guide, the instructions in this RFA should be followed.**

Technical questions pertaining to the electronic submission process,
including registration through Grants.gov, the PureEdge Viewer software
required to download, complete, and submit electronic applications, or
problems related to the Grants.gov website should be directed to
Grants.gov staff. They can be reached by phone at 1-800-518-GRANTS or
via email at <support@grants.gov>.

Online resources to help potential applicants with the new electronic
application package and submission requirements are available at
[http://www.grants.gov](http://www.grants.gov/). Additional online
resources are provided by CSREES to help applicants, including tips for
preparing an electronic application and electronic submission frequently
asked questions at <http://www.csrees.usda.gov/funding/electronic>.

**[Closing Date for Applications]{.underline}**

Applications must be received by 5:00 PM Eastern Time (ET) on the date
detailed in the program description listed in the Program Opportunities
(Part II E) section of this RFA and in **TABLE 5 NRI PROGRAM DEADLINE
DATES** at the end of the document.

**[Application Receipt Notices]{.underline}**

After an application is submitted, the AOR will receive a series of four
e-mails. It is extremely important that the AOR watch for and save each
of the e-mails. The Grants.gov validation (email #2) may take up to two
business days from application submission. Please plan accordingly and
submit early. Receipt of e-mail Number 4 by the AOR indicates the
application reached CSREES, USDA. To track a submission, use the
Submission Receipt Number in e-mail Number 1. The titles of the four
e-mails are:

Number 1 -- Grants.gov Submission Receipt Number

Number 2 -- Grants.gov Submission Validation Receipt for Application
Number

Number 3 -- Grants.gov Grantor Agency Retrieval Receipt for Application
Number

Number 4 -- Receipt of Grant Application Number for Review at USDA

Receipt of the four e-mails does not indicate the application has been
accepted for review. The AOR and/or PD will be notified in up to two
subsequent e-mails if the application has been accepted or declined for
program review. If accepted, the application will be assigned a CSREES
application number (i.e. 2008-XXXXX). This number should be cited on all
future correspondence, see this section part E for additional
information.

## B. Content and Form of Application Submission 

**Electronic applications should be prepared according to the document
entitled** "[CSREES Grants.gov Application Guide: A Guide for
Preparation and Submission of CSREES Applications via
Grants.gov](http://www.csrees.usda.gov/funding/grant_forms/electronic_app_guide.pdf)."
This guide is part of the corresponding electronic application package,
see this section part A. The following is **additional information**
needed to prepare an application in response to this RFA. **If any
discrepancy between the two documents exists, the information contained
in this RFA is overriding.**

> **1. Integrated and Standard Research Grant Applications**
>
> **a. [General]{.underline}**
>
> Use the CSREES Grants.gov Application Guide and the following
> guidelines to prepare an application. Proper preparation of
> application will assist reviewers in evaluating the merits of each
> application in a systematic, consistent fashion:
>
> \(1\) Attachment Format
>
> CSREES will only accept attachments in the portable document format
> (PDF). See Part III of the CSREES Grants.gov Application Guide. PDF
> generating software can be obtained from the Grants.gov Customer
> Resources Web page
> (<http://www.grants.gov/resources/download_software.jsp>). **SUBMITTED
> PROPOSALS THAT DO NOT MEET THESE REQUIREMENTS FOR PDF ATTACHMENTS ARE
> AT RISK FOR BEING RETURNED WITHOUT REVIEW. Submitted PDF documents
> must have one-inch margins, line spacing of no less than six lines per
> inch, and no font smaller than 12 point. Number each page of the
> attachment sequentially. Please follow the page limitations for a
> given attachment in this RFA. Title each attachment in the document
> header [and]{.underline} save each file with name listed below, see
> this section part B(3).**
>
> \(2\) Grant Application Package
>
> \(a\) "*Competition ID*" no information will be auto-populated because
> CSREES does not utilize this feature. Please leave this field blank.
>
> \(b\) "*Application Filing Name*" is required. There are no specific
> guidelines for this field. However, it must be completed and the
> applicant may enter a name or number they deem appropriate.
>
> \(3\) In the process of submitting your proposal electronically, you
> will complete at least seven components of the SF 424 Research and
> Related (R&R) Application Package:

-   SF 424 R&R Cover Sheet

-   R&R Other Project Information

-   R&R Senior/Key Person Profile

-   R&R Personal Data

-   R&R Budget

-   Supplemental Information Form (including Conflict of Interest)

-   NRI Proposal Type Form

-   R&R Sub-award, as appropriate

> **All applications must be submitted through Grants.gov.**
>
> **b. [SF 424 R&R Cover Sheet]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part V, 2. of the CSREES Grants.gov Application Guide.
>
> \(1\) *Field 5.* *Legal Name* -- Enter the legal name of the
> organization to which the award should be made.
>
> \(2\) *Person to be contacted on matters involving this application*
> -- Enter the information for the contact person related to this
> application preferred by the institution. It is anticipated that the
> NRI official program correspondence will be maintained with the AOR or
> PD depending if the topic is administrative or scientific.
>
> \(3\) *Field 11.* *Descriptive Title of Applicant's Project* -- The
> title should be a brief (**140-character-maximum including spaces**),
> clear, and concise description of the proposed project.
>
> \(4\) *Field 13.* *Proposed Project* -- For the start date of the
> project, select a date at least six months after the submission due
> date for the program. Choose the end date to correspond to the correct
> duration of the project.
>
> \(5\) *Field 20.* *Pre-application* -- Do not fill out this portion of
> the form. The NRI is [not]{.underline} accepting pre-applications in
> fiscal year 2008 in any of the programs. Some programs may require a
> Letter of Intent. See program descriptions for more details.
>
> **c. [R&R Other Project Information]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part V, 3. of the CSREES Grants.gov Application Guide.
>
> For the purpose of this RFA, questions in Field 4 pertain to the
> National Environmental Policy Act of 1969 (NEPA). Under 7 CFR Part
> 3407 (CSREES's implementing regulations of NEPA), CSREES must
> determine whether the proposed activity requires the preparation of an
> environmental assessment or an environmental impact statement, or
> whether such activity can be excluded from this requirement on the
> basis of several categories. Note that even though the applicant
> considers that a proposed project may or may not fall within a
> categorical exclusion, CSREES may determine that an environmental
> assessment or an environmental impact statement is necessary for a
> proposed project should substantial controversy on environmental
> grounds exist or if other extraordinary conditions or circumstances
> are present that may cause such activity to have significant
> environmental effect. **It is requested that Field 4 be completed in
> the following manner.**
>
> \(1\) *Field 4a*. -- Check yes.
>
> \(2\) *Field 4b. If yes, please explain* -- Type "See Field 4d below."
>
> \(3\) *Field 4c. If this project has actual or potential impact on the
> environment, has an exemption been authorized or an environmental
> assessment (EA) or environmental impact statement (EIS) been
> performed?*
>
> The applicant should review the categorical exclusions in the table on
> the next page and determine if the proposed project falls within one
> or more of the exclusions.
>
> Check "Yes" if one of the categorical exclusion listed in the table on
> the next page applies. Also, check yes if an EA or EIS has been
> performed. Attach a copy of the EA or EIS, if performed, in Field 11.
> Other Attachments.
>
> Check "No" if the proposed activity does [not]{.underline} fall into
> one of the categorical exclusions listed in the table below OR if an
> EA or EIS has [not]{.underline} been performed. If "No" is checked,
> attach an explanation of the potential environmental impacts of the
> proposed activity in Field 11. Other Attachments. This may require
> completion of an EA or EIS.
>
> \(4\) *Field 4d*. If applicable, enter the appropriate Exclusion Code
> in Field 4d. If an EA or EIS file is attached in "Field 11. Other
> Attachments," enter "Please see attached."

**USDA CSREES NEPA Exclusion Codes Table**

  ----------------- -------------------------------------------------------
  **Exclusion       **Description**
  Code**            

  *Department of    
  Agriculture       
  Categorical       
  Exclusions (found 
  at 7 CFR 1b.3 and 
  restated at 7 CFR 
  3407.6(a)(1)(i)   
  through (vii))*   

  (a)(1)(i)         Policy development, planning, and implementation which
                    are related to routine activities such as personnel,
                    organizational changes, or similar administrative
                    functions

  (a)(1)(ii)        Activities that deal solely with the functions of
                    programs, such as program budget proposals,
                    disbursement, and transfer or reprogramming of funds

  (a)(1)(iii)       Inventories, research activities, and studies such as
                    resource inventories and routine data collection when
                    such actions are clearly limited in context and
                    intensity

  (a)(1)(iv)        Educational and informational programs and activities

  (a)(1)(v)         Civil and criminal law enforcement and investigative
                    activities

  (a)(1)(vi)        Activities that are advisory and consultative to other
                    agencies and public and private entities, such as legal
                    counseling and representation

  (a)(1)(vii)       Activities related to trade representation and market
                    development activities abroad

                    

  *CSREES           
  Categorical       
  Exclusions (found 
  at 7 CFR          
  3407.6(a)(2)(i)   
  through (ii))*    

  The following     
  categories of     
  research programs 
  or projects of    
  limited size and  
  magnitude or with 
  only short-term   
  effects on the    
  environment:      

  (a)(2)(i)(A)      Research conducted within any laboratory, greenhouse,
                    or other contained facility where research practices
                    and safeguards prevent environmental impacts

  (a)(2)(i)(B)      Surveys, inventories, and similar studies that have
                    limited context and minimal intensity in terms of
                    changes in the environment

  (a)(2)(i)(C)      Testing outside the laboratory, such as in small
                    isolated field plots, which involves the routine use of
                    familiar chemicals or biological materials

  (a)(2)(ii)        Routine renovation, rehabilitation, or revitalization
                    of physical facilities, including the acquisition and
                    installation of equipment, where such activity is
                    limited in scope and intensity
  ----------------- -------------------------------------------------------

> \(5\) *Field 6. Project Summary/Abstract* -- **PDF Attachment**. The
> Project Summary is limited to **250 words**. Title the attachment as
> 'Project Summary' in the document header [and]{.underline} save file
> as 'Project Summary'.
>
> A suggested template for the Project Summary/Abstract can be found at:
> <http://www.csrees.usda.gov/funding/templates/project_summary.doc>.
>
> The Project Summary must indicate which specific FY 2008 Program
> Priority(ies) the proposed project addresses. Program Priorities are
> stated within each Program Opportunity description (see Part II, E.).
> The importance of a concise, informative Project Summary cannot be
> overemphasized.
>
> \(6\) *Field 7. Project Narrative* (formerly Project Description) --
> **PDF Attachment. 18-Page or 7-Page Limit (explained below).** Title
> the attachment as 'Project Narrative' in the document header
> [and]{.underline} save file as 'Project Narrative'.
>
> **PLEASE NOTE: For Integrated, Standard Research, Strengthening
> Standard Research, Postdoctoral Fellowships, New Investigator, and
> Conference grant applications, the Project Narrative section may not
> exceed a total of 18 single- or double-spaced pages, including figures
> and tables. For Research Career Enhancement, Equipment, and Seed Grant
> Applications, the Project Narrative section may not exceed a total of
> 7 single- or double-spaced pages, including figures and tables.** This
> page limitation applies regardless of whether figures or tables are
> included. All pages, including those with figures and tables, should
> be numbered sequentially. Applications exceeding the applicable page
> limitation will be returned without review. The page limit has been
> established to ensure fair and equitable competition.
>
> **Project Narrative must include all of the following**:
>
> \(a\) *Response to Previous Review* (if applicable). This requirement
> only applies to "Resubmitted Applications" and "Resubmitted Renewal
> Applications" as described in Part II, B. PDs must respond to the
> previous review panel summary on **no more than one page**, titled
> "RESPONSE TO PREVIOUS REVIEW." If desired, additional comments may be
> included in the text of the Project Narrative, which is subject to the
> 18 page limitation for this section. When a Response to Previous
> Review is included in the Project Narrative, the attachment page
> limitation is increased to 19 total pages to include the 1-page
> response. Note, the Project Narrative itself, with or without the
> Response to Previous Review, must not exceed 18-pages.
>
> \(b\) *Introduction*. The introduction should include a clear
> statement of the long-term goal(s) and supporting objectives or
> research questions of the proposed project. Summarize the body of
> knowledge or other past activities that substantiate the need for the
> proposed project. Describe ongoing or recently completed significant
> activities related to the proposed project including the work of key
> project personnel. Include preliminary data/information pertinent to
> the proposed research. All works cited should be referenced (see item
> (7) Bibliography & Reference Cited of this section).
>
> \(c\) *Progress Report*. If the application is a renewal of an
> existing project supported under this program (or its predecessor),
> include a clearly marked progress report describing results to date
> from the previous award. The progress report must be contained within
> the 18-page limit and should contain the following information:

1.  A comparison of actual accomplishments with the objectives
    established for the previous award;

2.  The reasons established objectives were not met, if applicable; and

3.  A listing of any publications resulting from the award.

> Copies of no more than two preprints or reprints may be appended to
> the application (see item (10)(g) Appendices to Project Narrative of
> this section). Appendices are not counted toward the 18-page Project
> Narrative limit.
>
> \(d\) *Rationale and Significance*.

1.  Concisely present the rationale behind the proposed research,
    extension, or education;

2.  The specific relationship of the project's objectives to one or more
    of the particular program priorities; and

3.  The potential long-range improvement in and sustainability of U.S.
    agriculture and food systems should be shown clearly. These purposes
    are described under Part I, B., Purpose and Priorities. Any novel
    ideas or contributions that the proposed project offers should also
    be discussed in this section.

> \(e\) *Approach.* The activities proposed or problems being addressed
> must be clearly stated and the approaches being applied clearly
> described. Specifically, this section must include:

-   A description of the activities proposed and the sequence in which
    the activities are to be performed;

-   Methods to be used in carrying out the proposed project, including
    the feasibility of the methods;

-   Expected outcomes;

-   Means by which results will be analyzed, assessed, or interpreted;

-   How results or products will be used;

-   Pitfalls that may be encountered;

-   Limitations to proposed procedures;

-   A full explanation of any materials, procedures, situations, or
    activities related to the project that may be hazardous to
    personnel, along with an outline or precautions to be exercised to
    avoid or mitigate the effects of such hazards; and

-   A brief timeline of the proposed project.

> \(7\) *Field 8. Bibliography & References Cited* -- **PDF
> Attachment**. **No Page Limit.** Title the attachment as 'Bibliography
> & References Cited' in the document header [and]{.underline} save file
> as 'Bibliography & References Cited'.
>
> All work cited in the text, including that of key personnel, should be
> referenced in this section of the application. All references must:
>
> \(a\) Be complete;
>
> \(b\) Include titles and all co-authors;
>
> \(c\) Conform to an acceptable journal format; and
>
> \(d\) Be listed in alphabetical order using the last name of the first
> author or listed by number in the order of citation.
>
> See the example provided Part III, 3.8. of the CSREES Grants.gov
> Application Guide. References are not considered in the
> page-limitation for the Project Narrative.
>
> \(8\) *Field 9. Facilities & Other Resources* -- **PDF Attachment. No
> Page Limit.** Title the attachment as 'Facilities & Other Resources'
> in the document header [and]{.underline} save file as 'Facilities &
> Other Resources'.
>
> \(9\) *Field 10. Equipment* **-- PDF Attachment**. **No Page Limit.**
> Title the attachment as 'Equipment' in the document header
> [and]{.underline} save file as 'Equipment'.
>
> In addition to describing available equipment, items of nonexpendable
> equipment necessary to conduct and successfully complete the proposed
> project should be listed in Field C. of the R&R Budget and described
> in the Budget Justification (Field K of the R&R Budget).
>
> \(10\) *Field 11. Other Attachments*
>
> \(a\) **See item (6) Project Narrative of this section for the
> Response to Previous Review.** The Response to Previous Review will
> now be located within the Project Narrative attachment. Do not attach
> the Response to Previous Review in this section.
>
> \(b\) *Key Personnel Roles* -- **PDF Attachment. 2-Page Limit.** Title
> the attachment as 'Key Personnel' [and]{.underline} save file as 'Key
> Personnel'.
>
> Clearly describe the roles and responsibilities of the PD, co-PD(s),
> and/or collaborator(s). Biographical sketches for key personnel should
> be attached in the R&R Senior/Key Person Profile. If it will be
> necessary to enter into formal consulting or collaborative
> arrangements with others, such arrangements should be fully explained
> and justified. If the consultant(s) or collaborator(s) are known at
> the time of application, a biographical sketch should be provided in
> the R&R Senior/Key Person Profile. Collaborators simply providing
> services or materials should not be listed in the R&R Senior/Key
> Person Profile and a biographical sketch is not required. Evidence
> (letters of support) for this type of collaboration should be provided
> in the 'Documentation of Collaboration', see this section part B. 1,
> c., (10)(e) of this document.
>
> \(c\) *Logic Model* -- **PDF Attachment. For Integrated Projects Only.
> 2-Page Limit**. Title the attachment as 'Logic Model'
> [and]{.underline} save file as 'Logic Model'.
>
> \(d\) *Management Plan* -- **PDF Attachment. For Integrated Projects
> Only. 3-Page Limit.** Title the attachment as 'Management Plan'
> [and]{.underline} save file as 'Management Plan'.
>
> Because of the complexity of integrated projects, it is important to
> have a clearly articulated management plan. Include a timeline for
> attainment of objectives and for production of deliverables, as well
> as a strategy to enhance coordination, collaboration, communication,
> and data sharing and reporting among members of the project team and
> stakeholder groups.
>
> \(e\) *Documentation of Collaboration* -- **PDF Attachment**. **No
> Page Limit.** Title the attachment as 'Documentation of Collaboration'
> in the document header [and]{.underline} save file as 'Documentation
> of Collaboration'.
>
> Evidence, e.g. letter(s) of support, should be provided that the
> collaborators involved have agreed to render services. The applicant
> also will be required to provide additional information on consultants
> and collaborators in the budget portion of the application.
>
> \(f\) *Results from Prior NRI Support* -- **PDF Attachment**. **1-Page
> Limit per Award.** Title the attachment as 'Results from Prior NRI
> Support' in the document header [and]{.underline} save file as
> 'Results from Prior NRI Support'.
>
> If the PD or a co-PD has received NRI support in the past five years,
> information on results from that prior funding is required. This
> information will be used in the review of the application. For renewal
> applications, provision of the Progress Report, see Project Narrative,
> is sufficient and information need not be repeated in this section.
> For each award, list the CSREES award number, the amount and period of
> support, the title of the project, a summary of the results of the
> completed work, the long-term effects of these results, and the
> publications resulting from the NRI award.
>
> \(g\) *Appendices to Project Narrative* -- **PDF Attachment.** Title
> the attachment as 'Appendices' in the document header
> [and]{.underline} save file as 'Appendices'.
>
> Appendices are strictly limited to a **maximum of 2** of the following
> items in any combination:

-   Reprints (papers that have been published in peer-reviewed
    journals); and

-   Preprints (only manuscripts in press for a peer-reviewed journal
    will be accepted and must be accompanied by letters of acceptance
    from the publishing journals). Preprints attached in support of the
    application should be single-spaced. Each preprint must be
    identified with the name of the submitting organization, the name(s)
    of the PD(s), and the title of the application.

> Each Project Narrative is expected to be complete; however, additions
> to the Project Narrative (appendices) are allowed if they are directly
> germane to the proposed project. Information may not be appended to an
> application to circumvent page limitations prescribed for the Project
> Narrative. Extraneous materials [will not]{.underline} be used during
> the peer review process.
>
> \(h\) *Other Documents (as requested)* - **PDF Attachment.** Title the
> attachment as indicated in the program description or RFA directions.
> In the document header [and]{.underline} save file with the same
> title.
>
> **d. [R&R Senior/Key Person Profile]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part V, 4. of the CSREES Grants.gov Application Guide. A
> Senior/Key Person Profile should be completed for the PD and each
> co-PD, senior associate, and other professional personnel, including
> collaborators playing an active role in the project. Collaborators
> only providing services or materials should not be listed in the R&R
> Senior/Key Person Profile. Evidence (letters of support) for this type
> of collaboration should be provided in the Documentation of
> Collaboration, see this section part B,1 c. (10)(e) of this document.
>
> \(1\) *Attach Biographical Sketch Field* -- **PDF Attachment. 2-Page
> Limit (excluding publications listings) per PD, co-PD, senior
> associate, and other professional personnel.** Title the attachment as
> 'Biographical Sketch' in the document header [and]{.underline} save
> file as 'Biographical Sketch'.
>
> A biographical sketch (vitae) of the PD and each co-PD, senior
> associate, and other professional personnel should be included.
>
> The Conflict of Interest list should not be included in the
> biographical sketch, but it must be provided as a separate document,
> see this section B, 1 g.(3) of this document.
>
> \(2\) *Attach Current and Pending Support Field* -- **PDF Attachment.
> No Page Limit.** Title the attachment as 'Current and Pending Support'
> in the document header [and]{.underline} save file as 'Current and
> Pending Support'.
>
> A suggested template for the Current and Pending Support can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/current_pending.doc>.
>
> Current and Pending Support information is only required for personnel
> with PD or co-PD indicated as their Project Role on the R&R Senior/Key
> Person Profile. All applications must contain a list of all Current
> and Pending Support detailing public or private support (including
> in-house support) to which personnel identified in the application
> have committed portions of their time, whether or not salary support
> for person(s) involved is included in the budget, see template. Please
> note that the project being proposed should be included in the pending
> section of the form. Total project time listed for each PD should be
> indicated as percent effort and not exceed 100% for concurrent
> projects.
>
> **e. [R&R Personal Data]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part V, 5. of the CSREES Grants.gov Application Guide.
> Provide a brief summary for a current or pending project that appears
> similar to the current proposal.
>
> **f. [R&R Budget]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part V, 6. of the CSREES Grants.gov Application Guide.
>
> \(1\) *Budget Periods*. Applications must contain a budget for each
> budget period for the entire duration of the proposed project. Annual
> and cumulative budgets are required. Applicants must complete the
> mandatory fields on each page of the first budget period and attach
> the Budget Justification (see item (4) Field K. Budget Justification,
> of this section) to enable the "Next Period" button to become active.
>
> \(2\) *Subcontract Arrangements*. If it will be necessary to enter
> into a formal subcontract agreement with another institution,
> financial arrangements must be detailed in the "R&R Subaward Budget
> Attachment(s) Form." Annual and cumulative budgets and a budget
> justification are required for each subcontract agreement. Refer to
> Part V, 7. of the CSREES Grants.gov Application Guide for instructions
> on completing this form.
>
> \(3\) *Field H. Indirect Costs* -- See Section D in this section of
> this guide for indirect cost information.
>
> \(4\) *Field K. Budget Justification* -- **PDF Attachment. No Page
> Limit.** Title the attachment as 'Budget Justification' in the
> document header [and]{.underline} save file as 'Budget Justification'.
>
> All budget categories, with the exception of Indirect Costs, for which
> support is requested must be individually listed (with costs) in the
> same order as the budget. If consulting, collaborative, or
> subcontractual arrangements are included in the application, these
> arrangements should be fully explained and justified. The rate of pay
> for any consultant must be included, if known at the time of
> application. Please include a cost breakdown for the consultant,
> including the number of days in service, travel, and per diem, as well
> as the rate of pay. Letters of consent or collaboration and other
> evidence should be provided in the Documentation of Collaboration (see
> item c., (10)(e) of this section) to show that collaborators have
> agreed to participate. A proposed statement of work, biographical
> sketch, and a budget for each arrangement involving the transfer of
> substantive programmatic work or the provision of financial assistance
> to a third party must be supplied. In multi-institutional
> applications, a budget and budget narrative must be included for each
> institution involved. The lead institution and each participating
> institution must be identified.
>
> \(5\) *Matching*
>
> Equipment grants requiring matching funds must include a letter signed
> by the institution's authorized organizational representative stating
> that the necessary non-Federal matching funds will be made available
> from an institution or other source. If the institution is eligible
> for the waiver for matching funds, the budget justification must
> include a letter signed by the institution's authorized organizational
> representative stating this information (see Table 2 for eligibility).
>
> Applicants submitting an integrated application that the applicant
> determines does not require matching funds (as specified under Part
> III, C.) should include a justification in the Budget Justification.
> CSREES will consider this justification when ascertaining final
> matching requirements. CSREES retains the right to make final
> determinations regarding matching requirements.
>
> Applicants submitting an integrated application that does require
> matching funds (as specified under Part III, C.) should provide
> written verification of commitments of matching support (including
> both cash and in-kind contributions) from third parties (non-federal
> sources) in the Budget Justification file. Written verification means
> third party cash contributions should include a separate pledge
> agreement for each donation, signed by the authorized organizational
> representative of the donor organization and the applicant
> organization. Each agreement should include: (1) the name, address,
> and telephone number of the donor; (2) the name of the applicant
> organization; (3) the title of the project for which the donation is
> made; (4) the dollar amount of the cash donation; and (5) a statement
> that the donor will pay the cash contribution during the grant period.
>
> The sources and the amount of all matching support from outside the
> applicant organization should be summarized on a separate page and
> placed in the application immediately following the Budget
> Justification. All pledge agreements must be placed in the application
> immediately following the summary of matching support.
>
> The value of applicant contributions to the project shall be
> established in accordance with the applicable cost principles.
> Applicants should refer to OMB Circulars A-21, Cost Principles for
> Educational Institutions, A-87, Cost Principles for State, Local, and
> Tribal Governments, A-122, Cost Principles for Non-Profit
> Organizations, and the cost principles in the Federal Acquisition
> Regulation at 48 CFR 31.2 for further guidance and other requirements
> relating to matching and allowable costs.
>
> **g. [Supplemental Information Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 1. of the CSREES Grants.gov Application Guide.
>
> \(1\) *Field 1. Funding Opportunity* -- Funding Opportunity Name is
> pre-populated with "National Research Initiative Competitive Grants
> Program" and "USDA-CSREES-NRI-001030" for Funding Opportunity Number
> in Field 1.
>
> \(2\) *Field 2. Program to which you are applying* -- Use the chart
> below to determine the\
> Program Code Name and Program Code to which you are applying. A
> proposal can only be submitted to one program. It is extremely
> important that the Program Code Name and Program Code are spelled
> correctly and match this RFA. If you have a question about which topic
> area is appropriate for your proposal, please contact the National
> Program Leader for that program.

  --------------------------------------------------------------- -----------
  **Program Code Name**                                           **Program
                                                                  Code**

  Plant Biosecurity                                               20.2

  Managed Ecosystems                                              23.1

  Soil Processes                                                  25.0

  Water and Watersheds                                            26.0

  Global and Climate Change                                       27.0

  Air Quality                                                     28.0

  Bioactive Food Components for Optimal Health                    31.0

  Human Nutrition and Obesity                                     31.5

  Food Safety and Epidemiology (A): Biological Approaches for     32.0
  Food Safety                                                     

  Food Safety and Epidemiology (B): Epidemiological Approaches    32.0
  for Food Safety                                                 

  Animal Reproduction                                             41.0

  Animal Growth and Nutrient Utilization                          42.0

  Animal Genome (A): Translational Animal Genomics                43.0

  Animal Genome (B): Tools and Resources                          43.0

  Animal Genome (C): Bioinformatics                               43.0

  Animal Genome (D): Functional Genomics                          43.0

  Animal Genome (E): Whole Genome Enabled Animal Selection        43.0

  Animal Protection and Biosecurity (A): Animal Disease           44.0

  Animal Protection and Biosecurity (B): Animal Well-Being        44.0

  Animal Protection and Biosecurity (C): Animal Biosecurity       44.0
  Coordinated Agricultural Project (CAP)                          

  Microbial Genomics (A): Genome Sequencing                       51.0

  Microbial Genomics (B): Functional Genomics of Microorganisms   51.0

  Arthropod and Nematode Biology and Management (A): Organismal   51.2
  and Population Biology                                          

  Arthropod and Nematode Biology and Management (B):              51.2
  Suborganismal Biology                                           

  Arthropod and Nematode Biology and Management (C): Tools,       51.2
  Resources, and Genomics                                         

  Arthropod and Nematode Biology and Management (D): Protection   51.2
  of Managed Bees CAP                                             

  Microbial Biology (A): Microbial Observatories                  51.8

  Microbial Biology (B): Microbial Associations with Plants       51.8

  Biology of Weedy and Invasive Species in Agroecosystems         51.9

  Plant Genome (A): Tools, Resources, and Bioinformatics          52.1

  **Program Code Name**                                           **Program
                                                                  Code**

  Plant Genome (B): Functional Genomics                           52.1

  Plant Genome (C): Genome Structure and Organization             52.1

  Plant Genome (D): Applied Plant Genomics Coordinated            52.1
  Agricultural Project (CAP)                                      

  Plant Biology (A): Gene Function and Regulation                 56.0

  Plant Biology (B): Environmental Stress                         56.0

  Plant Biology (C): Biochemistry                                 56.0

  Plant Biology (D): Growth and Development                       56.0

  Plant Biology (E): Plant Breeding and Education                 56.0

  Agribusiness Markets and Trade                                  61.0

  Rural Development                                               62.0

  Agricultural Prosperity for Small and Medium-Sized Farms        66.0

  Improving Food Quality and Value                                71.1

  Biobased Products and Bioenergy Production Research             71.2

  Nanoscale Science and Engineering for Agriculture and Food      75.0
  Systems                                                         
  --------------------------------------------------------------- -----------

> \(3\) **IMPORTANT -** *Field 8. Conflict of Interest* List -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>.
>
> A Conflict of Interest List [must]{.underline} be provided for all
> individuals who have submitted a Biographical Sketch in response to
> item d., (1) of this section. Collate all Conflict of Interest lists
> into a single document. The lists can only be submitted as a single
> PDF attachment.
>
> For all individuals who have submitted a Biographical Sketch, list
> [alphabetically by last name]{.underline} (and with last name first)
> the full names of individuals and indicate which categorical
> conflict(s) listed below applies:
>
> \(a\) All [co-authors]{.underline} on publications within the past
> three years, including pending publications and submissions;
>
> \(b\) All [collaborators]{.underline} on projects within the past
> three years, including current and planned collaborations;
>
> \(c\) All thesis or postdoctoral [advisees/advisors]{.underline}; and
>
> \(d\) All persons in your field with whom you have had a
> [consulting/financial arrangement/other]{.underline}
> conflict-of-interest in the past three years.
>
> Note: Other individuals working in the applicant\'s specific area are
> not in conflict with the applicant unless those individuals fall
> within one of the listed categories. The National Program Leader
> responsible for the topic area [must]{.underline} be informed of any
> additional conflicts of interest that arise after the application is
> submitted.
>
> **h. [NRI Proposal Type Form]{.underline} -**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.
>
> \(1\) *Field 1. Proposal Type* --
>
> For Integrated Grant Applications, select "Integrated Project
> Proposal."
>
> For Standard Research Grant Applications, select "Research Project
> Proposal" and "Standard Research Project."
>
> **2. Research Conference Applications**
>
> Submit applications requesting support for conferences to appropriate
> programs, described in Part II, E., by applicable deadlines.
> **Potential applicants are strongly advised to consult the appropriate
> National Program Leader before preparing their conference
> application.** To submit a Research Conference application, follow the
> guidelines for Integrated and Standard Research Grant Applications
> (Part IV, B., 1.), noting the following differences:
>
> **a. [R&R Other Project Information Form]{.underline}**
>
> \(1\) *Field 6. Project Summary/Abstract* -- **PDF Attachment.** Title
> the attachment as 'Project Summary' in the document header
> [and]{.underline} save file as 'Project Summary'.
>
> State the objectives of the conference, symposium, or workshop, as
> well as the proposed location and probable inclusive date(s) of the
> conference. Please state in the summary the specific program
> priority(ies) to which the project applies.
>
> \(2\) *Field 7. Project Narrative* (formerly Project Description) --
> **PDF Attachment. 18-Page Limit.** Title the attachment as 'Project
> Narrative' in the document header [and]{.underline} save file as
> 'Project Narrative'.
>
> **PLEASE NOTE: For Research Conference Grant Applications, the Project
> Narrative section may not exceed a total of 18 single- or
> double-spaced pages, including figures and tables.** These page
> limitations apply regardless of whether figures or tables are
> included. All pages, including those with figures and tables, should
> be numbered sequentially. Applications exceeding the applicable page
> limitation will be returned without review. The page limitations have
> been established to ensure fair and equitable competition.
>
> Describe the conference proposed, including:
>
> \(a\) A justification for the meeting;
>
> \(b\) Recent meetings on the same subject with dates and locations;
>
> \(c\) Names and organizational affiliations of the chair and other
> members of the organizing committee;
>
> \(d\) A proposed program (or agenda) for the conference, including a
> listing of scheduled participants and their institutional
> affiliations; and
>
> \(e\) The method of announcement or invitation that will be used.
>
> **b. [R&R Senior/Key Person Profile]{.underline}**
>
> \(1\) *Attach Biographical Sketch Field* -- **PDF Attachment. 2-Page
> limit (including publications listings) per submitting PD(s).** Title
> the attachment as 'Biographical Sketch' in the document header
> [and]{.underline} save file as 'Biographical Sketch'.
>
> Include a Biographical Sketch for submitting PD(s) with a
> [brief]{.underline} listing of relevant publications.
>
> The Conflict of Interest lists should not be included in the
> biographical sketch and must be provided as a separate document, see
> item d. (1) of this section.
>
> **c. [R&R Budget]{.underline}**
>
> The budget for the conference may include an appropriate amount for
> transportation and subsistence costs for participants and for other
> conference-related costs. Conference awards are not expected to exceed
> \$10,000 and are not renewable. Conference awards may not include
> indirect costs. Include an itemized breakdown of all support requested
> from the NRI in the Budget Justification (Field K. of the R&R Budget).
>
> **d. [Supplemental Information Form]{.underline}**
>
> \(1\) **IMPORTANT -** *Field 8. Conflict of Interest List* -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>.
>
> Include for all submitting PD(s).
>
> **e. [NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.
>
> \(1\) *Field 1. Proposal Type* -- For Research Conference
> Applications, select "Research Project Proposal" and "Conference."
>
> **3. Agricultural Research Enhancement Award (AREA) Applications**
>
> **a. [Postdoctoral Fellowships]{.underline}**
>
> See Part II, C., 2(a) and Part III, A. for eligibility requirements.
>
> Submit applications requesting support for postdoctoral fellowships to
> appropriate research programs, described in Part II, E., by applicable
> deadlines. An individual may submit an application directly or through
> the mentor\'s institution. Postdoctoral applicants must be the sole PD
> listed on the application. The mentor should not be listed as a co-PD
> (see item (3)(b) of this section). To submit a Postdoctoral Fellowship
> application, follow the guidelines for Integrated and Standard
> Research Grant Applications (see this section B., 1.), noting the
> following differences:
>
> \(1\) **[SF 424 R&R Cover Sheet]{.underline}**
>
> If the application is submitted through an institution, the SF 424 R&R
> Cover Sheet must be endorsed by the AOR who possesses the necessary
> authority to commit the applicant\'s time and other relevant
> resources. If an application is to be submitted by an individual, the
> submitting individual must be the proposing postdoctoral applicant.
>
> \(2\) **[R&R Other Project Information]{.underline}**
>
> \(a\) *Field 1 and 2.* *Are Human Subjects Involved?* and *Are
> Vertebrate Animals Used?* -- Postdoctoral fellowship applicants whose
> research requires use of human subjects or vertebrate animals must
> have their project reviewed by the appropriate committee(s) at the
> institution where the research will be conducted.
>
> \(b\) *Field 7. Project Narrative* (formerly Project Description) --
> **PDF Attachment. 18-Page Limit.** Title the attachment as 'Project
> Narrative' in the document header [and]{.underline} save file as
> 'Project Narrative'.
>
> **PLEASE NOTE: For Postdoctoral Grant Applications, the Project
> Narrative section may not exceed a total of 18 single- or
> double-spaced pages, including figures and tables.** These page
> limitations apply regardless of whether figures or tables are
> included. All pages, including those with figures and tables, should
> be numbered sequentially. Applications exceeding the applicable page
> limitation will be returned without review. The page limit has been
> established to ensure fair and equitable competition.
>
> \(c\) *Field 9.* *Facilities & Other Resources* -- **PDF Attachment.**
> Title the attachment as 'Facilities & Other Resources' in the document
> header [and]{.underline} save file as 'Facilities & Other Resources'.
>
> Provide documentation that arrangements have been made for the
> necessary facilities & other resources for conduct of the research.
>
> \(d\) *Field 10. Equipment* **-- PDF Attachment.** Title the
> attachment as 'Equipment' in the document header [and]{.underline}
> save file as 'Equipment'.
>
> Provide documentation that arrangements have been made for the
> necessary equipment for conduct of the research.
>
> \(e\) *Field 11. Other Attachments, Documentation of Collaboration* --
> **PDF Attachment.** Title the attachment as 'Documentation of
> Collaboration in the document header [and]{.underline} save file as
> 'Documentation of Collaboration.
>
> Provide documentation that arrangements have been made with an
> established investigator to serve as mentor. *The letter must provide
> assurance that the proposed project initiates the postdoctoral
> student\'s independent research program. Although the project may fit
> in the context of the mentor\'s existing research area, it should not
> simply be an extension of ongoing projects in the mentor\'s
> laboratory.*
>
> Also provide documentation from the host institution\'s AOR indicating
> that the host institution concurs with the proposed arrangements.
> Postdoctoral applicants from Federal laboratories must notify the
> appropriate regional office.
>
> \(3\) **[R&R Senior/Key Person Profile]{.underline}**
>
> A Senior/Key Person Profile must be completed for the Postdoctoral
> Fellowship applicant and their corresponding scientific mentor(s).
>
> \(a\) *Project Role* *Field* -- Select "Post Doctoral" for the
> Postdoctoral Fellowship applicant. Select "Other (Specify)" for the
> corresponding scientific mentor(s).
>
> \(b\) *Other Project Role* *Category Field* -- Enter "Mentor" for
> corresponding scientific mentor(s).
>
> \(c\) *Attach Current and Pending Support Field* -- **PDF
> Attachment.** Title the attachment as 'Current and Pending Support' in
> the document header [and]{.underline} save file as 'Current and
> Pending Support'.
>
> Current and Pending Support for both the postdoctoral applicant and
> the scientific mentor(s) (as documentation of on-going work in the
> mentor\'s laboratory) must be completed.
>
> \(4\) **[R&R Budget]{.underline}**
>
> The budget is limited to \$125,000 and 2 year duration. Funds should
> be requested primarily for salary support although other expenditures
> (e.g. supplies, travel, and publication costs) are allowable costs if
> properly justified. An institutional allowance not exceeding \$2,400
> per year is allowed. Indirect costs are not allowed. The institutional
> allowance should be included in Field F., Other Direct Costs, Line 8.
> of the R&R Budget.
>
> \(5\) **[Supplemental Information Form]{.underline}**
>
> \(a\) **IMPORTANT -** *Field 8.* *Conflict of Interest List* -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> Conflict of Interest list for both the postdoctoral applicant and the
> scientific mentor(s) must be completed.
>
> A suggested template for the Conflict of Interest List can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>.
>
> \(6\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.
>
> \(a\) *Field 1. Proposal Type* -- For Postdoctoral Fellowship
> Applications, select "Research Project Proposal," "Agricultural
> Research Enhancement Award (AREA)," and "Postdoctoral Fellowship."
>
> **b. [New Investigator Awards]{.underline}**
>
> See Part II, C., 2(b) and Part III, A. for eligibility requirements.
>
> New investigators should submit research applications to appropriate
> research programs, described in Part II, E., by applicable deadlines.
> To submit a New Investigator Award application, follow the guidelines
> for Integrated and Standard Research Grant Applications (Part IV, B.,
> 1.), noting the following differences:
>
> \(1\) **[R&R Other Project Information]{.underline}**
>
> \(a\) *Field 7.* *Project Narrative* (formerly Project Description) --
> **PDF Attachment. 18-Page Limit.** Title the attachment as 'Project
> Narrative' in the document header [and]{.underline} save file as
> 'Project Narrative'.
>
> **PLEASE NOTE: For New Investigator Grant Applications, the Project
> Narrative section may not exceed a total of 18 single- or
> double-spaced pages, including figures and tables.** These page
> limitations apply regardless of whether figures or tables are
> included. All pages, including those with figures and tables, should
> be numbered sequentially. Applications exceeding the applicable page
> limitation will be returned without review. The page limit has been
> established to ensure fair and equitable competition.
>
> \(2\) **[Supplemental Information Form]{.underline}**
>
> \(a\) **IMPORTANT -** *Field 8.* *Conflict of Interest List* -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>.
>
> \(3\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.
>
> \(a\) *Field 1.* *Proposal Type* -- For New Investigator Applications,
> select "Research Project Proposal," "Agricultural Research Enhancement
> Award (AREA)," and "New Investigator."
>
> **c. [Strengthening Awards]{.underline}**
>
> \(1\) [Research Career Enhancement Awards (Sabbatical
> Awards)]{.underline}. See Research Career Enhancement Awards
> (Sabbatical Awards) in Part II, C., 2(c) and Part III, A. for
> eligibility requirements. Applications from eligible faculty wishing
> to enhance their research capabilities through sabbatical leaves are
> encouraged.
>
> Applications should be submitted to appropriate research programs,
> described in Part II, E., by applicable deadlines. Applications should
> originate through the applicant\'s home institution. To submit a
> Research Career Enhancement Awards (Sabbatical Awards) application,
> follow the guidelines for Integrated and Standard Research Grant
> Applications (Part IV, B., 1.) noting the following differences:
>
> \(a\) **[R&R Other Project Information Form]{.underline}**

-   *Field 1 and 2. Are Human Subjects Involved?* and *Are Vertebrate
    Animals Used?* -- Applicants whose research requires use of human
    subjects or vertebrate animals must have their project reviewed by
    the appropriate committee(s) at the institution where the research
    will be conducted.

-   *Field 6.* *Project Summary/Abstract* -- **PDF Attachment.** Title
    the attachment as 'Project Summary' in the document header
    [and]{.underline} save file as 'Project Summary'.

> Indicate overall project goals and supporting objectives.
>
> *Field 7. Project Narrative* (formerly Project Description) -- **PDF
> Attachment. 7-Page Limit.** Title the attachment as 'Project
> Narrative' in the document header [and]{.underline} save file as
> 'Project Narrative'.
>
> **PLEASE NOTE: For Research Career Enhancement Grant Applications, the
> Project Narrative section may not exceed a total of 7 single- or
> double-spaced pages, including figures and tables.** These page
> limitations apply regardless of whether figures or tables are
> included. All pages, including those with figures and tables, should
> be numbered sequentially. Applications exceeding the applicable page
> limitation will be returned without review. The page limit has been
> established to ensure fair and equitable competition.

Describe the proposed sabbatical, including:

-   A general description of the research interests and goals of the
    applicant in order to provide perspective for the application;

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-   A description of the research project to be pursued while on the
    sabbatical leave;

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-   A statement of how the proposed activities will enhance the
    scientific research capabilities of the applicant; and

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-   A statement of future research goals and objectives once the
    sabbatical is complete and how the sabbatical will enable the
    applicant to pursue these goals.

> *Field. 11. Other Attachments, Documentation of Collaboration* --
> **PDF Attachment.** Title the attachment as 'Documentation of
> Collaboration' in the document header [and]{.underline} save file as
> 'Documentation of Collaboration'.
>
> Provide documentation that arrangements have been made with an
> established investigator(s) to serve as host, including:

-   A letter from the home institution detailing the particular
    arrangements at the home institution with respect to salary, and
    date and duration of sabbatical;

-   A letter from the scientific host(s) indicating willingness to serve
    in this capacity and a description of the host\'s contribution to
    the proposed activities both scientifically and with regard to use
    of facilities and equipment; and

-   A statement signed by the Department Head or equivalent official at
    the host institution indicating a commitment to provide research
    space and facilities for the period of the applicant\'s presence.

> \(b\) **[R&R Senior/Key Person Profile]{.underline}**
>
> A Senior/Key Person Profile must be completed for the Research Career
> Enhancement Awards (Sabbatical Awards) applicant, the corresponding
> scientific host(s), and any other personnel whose qualifications merit
> consideration in the evaluation of the application.

-   *Project Role Field* -- Select "PD/PI" for the Research Career
    Enhancement Awards (Sabbatical Awards) applicant. Select "Other" for
    the corresponding scientific host(s) and any other personnel whose
    qualification merit consideration in the evaluation of the
    application.

-   *Attach Biographical Sketch Field* -- **PDF Attachment.** Title the
    attachment as 'Biographical Sketch' in the document header
    [and]{.underline} save file as 'Biographical Sketch'.

> A Biographical Sketch must be submitted for the Research Career
> Enhancement Awards (Sabbatical Awards) applicant, the scientific
> host(s), and any other personnel whose qualifications merit
> consideration in the evaluation of the application.
>
> The Conflict of Interest lists should not be included in the
> biographical sketch and must be provided as a separate document (see
> item (d) of this section).

-   *Attach Current and Pending Support Field* -- **PDF Attachment.**
    Title the attachment as 'Current and Pending Support' in the
    document header [and]{.underline} save file as 'Current and Pending
    Support'.

> Current and Pending Support for both the Research Career Enhancement
> Awards (Sabbatical Awards) applicant and the scientific host(s) (as
> documentation of on-going work in the mentor\'s laboratory) must be
> completed.
>
> \(c\) **[R&R Budget]{.underline}**
>
> Limit to one year\'s salary and funds for travel and supplies.
>
> \(d\) **[Supplemental Information Form]{.underline}**
>
> **IMPORTANT -** *Field 8. Conflict of Interest* List -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> [http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc.](http://www.csrees.usda.gov/).
>
> Conflict of Interest list for the Research Career Enhancement Awards
> (Sabbatical Awards) applicant, the scientific host(s), and any other
> personnel whose qualifications merit consideration in the evaluation
> of the application must be completed.
>
> \(e\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.

-   *Field 1.* *Proposal Type* -- For Research Career Enhancement Award
    (Sabbatical Awards) Applications, select "Research Project
    Proposal," "Agricultural Research Enhancement Award (AREA),"
    "Strengthening," and "Career Enhancement."

> \(2\) [Equipment Grants]{.underline}. See Equipment Grants, in Part
> II, C., 2(c) and Part III, A. for eligibility requirements.
> Applications requesting assistance in purchasing one major piece of
> equipment must be submitted as Equipment Grant applications.
> Applications should be submitted to appropriate research programs,
> described in Part II, E., by applicable deadlines. To submit an
> Equipment Grant application, follow the guidelines for Integrated and
> Standard Research Grant Applications (Part IV, B., 1.), noting the
> following differences:
>
> \(a\) **[R&R Other Project Information Form]{.underline}**

-   *Field 6.* *Project Summary/Abstract* -- **PDF Attachment.** Title
    the attachment as 'Project Summary' in the document header
    [and]{.underline} save file as 'Project Summary'.

> Indicate equipment sought and overall project goals for its use.

-   *Field 7. Project Narrative* (formerly Project Description) -- **PDF
    Attachment. 7-Page Limit.** Title the attachment as 'Project
    Narrative' in the document header [and]{.underline} save file as
    'Project Narrative'.

> **PLEASE NOTE: For Equipment Grant Applications, the Project Narrative
> section may not exceed a total of 7 single- or double-spaced pages,
> including figures and tables.** These page limitations apply
> regardless of whether figures or tables are included. All pages,
> including those with figures and tables, should be numbered
> sequentially. Applications exceeding the applicable page limitation
> will be returned without review. The page limit has been established
> to ensure fair and equitable competition.
>
> Include general description of the research project(s) for which the
> equipment will be used, how the equipment will fit into or enhance the
> research program, and how the equipment will allow the applicant to
> become competitive for future funding or move into new research areas.
> Also include a brief description of other similar or complementary
> equipment available to the PD at the institution and why the requested
> equipment is necessary.
>
> \(b\) **[R&R Senior/Key Person Profile]{.underline}**
>
> A Senior/Key Person Profile must be completed for the Equipment Grant
> applicant and other major users of the equipment.

-   *Project Role* *Field* -- Select "PD/PI" for the Equipment Grant
    applicant. Select "Faculty" for the other major users of the
    equipment.

-   *Attach Biographical Sketch Field* -- **PDF Attachment.** Title the
    attachment as 'Biographical Sketch' in the document header
    [and]{.underline} save file as 'Biographical Sketch'.

> A Biographical Sketch for both the Equipment Grant applicant and other
> major users of the equipment must be submitted.
>
> The Conflict of Interest lists should not be included in the
> biographical sketch and must be provided as a separate document (see
> item (d) of this section).

-   *Attach Current and Pending Support Field* -- **PDF Attachment.**
    Title the attachment as 'Current and Pending Support' in the
    document header [and]{.underline} save file as 'Current and Pending
    Support'.

> Current and Pending Support for both the Equipment Grant applicant and
> other major users of the equipment must be completed. If the applicant
> has significant funding from other sources, a justification must be
> provided in the Project Narrative for how this equipment will
> strengthen the applicant's research program or institution.
>
> \(c\) **[R&R Budget]{.underline}**
>
> Each request shall be limited to one major piece of equipment within
> the cost range of \$10,000-\$250,000. The amount requested shall not
> exceed 50 percent of the cost or \$50,000, whichever is less. Unless
> waived, it is the responsibility of the PD to secure the required
> matching funds with non-Federal funds. No installation, maintenance,
> warranty, or insurance expenses may be paid from these awards, nor may
> these costs be part of the matching funds. Indirect costs are not
> permitted on Equipment Grant Awards.

-   *Field K. Budget Justification* -- **PDF Attachment.** Title the
    attachment as 'Budget Justification' in the document header
    [and]{.underline} save file as 'Budget Justification'.

> The Budget Justification should describe the instrument requested
> including the manufacturer and model number, if known; provide a
> detailed budget breakdown of the equipment and accessories required;
> and indicate the amount of funding requested from USDA for each
> component of equipment requested. A letter signed by the institution's
> AOR stating that the necessary non-Federal matching funds will be made
> available from an institutional or other source is required. An
> institution eligible for the waiver of the matching funds should
> include a letter stating and documenting the eligibility that is
> signed by the institution's AOR (see Table 2 for eligibility). A
> justification must be given for how this equipment will strengthen the
> applicant\'s research program or institution.
>
> \(d\) **[Supplemental Information Form]{.underline}**
>
> **IMPORTANT -** *Field 8. Conflict of Interest* List -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> [http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc.](http://www.csrees.usda.gov/).
>
> Conflict of Interest list for the Equipment Grant applicant and other
> major users of the equipment must be completed.
>
> \(e\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.

-   *Field 1. Proposal Type* -- For Equipment Grant Applications, select
    "Research Project Proposal," "Agricultural Research Enhancement
    Award (AREA)," "Strengthening," and "Equipment."

> \(3\) [Seed Grants]{.underline}. See Seed Grants, in Part II, C., 2(c)
> and Part III, A. for eligibility requirements. Applications from
> eligible faculty wishing to collect preliminary data should be
> submitted as Seed Grant applications. Applications should be submitted
> to appropriate research programs, described in Part II, E., by
> applicable deadlines. To submit a Seed Grant application, follow the
> guidelines for Integrated and Standard Research Grant Applications
> (Part IV, B., 1.), noting the following differences:
>
> \(a\) **[R&R Other Project Information Form]{.underline}**

-   *Field 7.* *Project Narrative* (formerly Project Description) --
    **PDF Attachment. 7-Page Limit.** Title the attachment as 'Project
    Narrative' in the document header [and]{.underline} save file as
    'Project Narrative'.

> **PLEASE NOTE: For Seed Grant Applications, the Project Narrative
> section may not exceed a total of 7 single- or double-spaced pages,
> including figures and tables.** These page limitations apply
> regardless of whether figures or tables are included. All pages,
> including those with figures and tables, should be numbered
> sequentially. Applications exceeding the applicable page limitation
> will be returned without review. The page limit has been established
> to ensure fair and equitable competition.
>
> Include all the components of a Standard Research Project application
> and present enough experimental detail to allow adequate evaluation.
> In order to be competitive, long-term research goals and a statement
> describing how this seed grant will allow the applicant to become
> competitive for future funding should be included.
>
> \(b\) **[R&R Budget]{.underline}**
>
> These awards will be limited to a total of \$100,000 (including
> indirect costs) for two years and are not renewable*.*
>
> \(c\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.

-   *Field 1. Proposal Type* -- For Seed Grant Applications, select
    "Research Project Proposal," "Agricultural Research Enhancement
    Award (AREA)," "Strengthening," and "Seed Grant."

> \(4\) [Strengthening Standard Research Project Awards]{.underline}.
> See Strengthening Standard Research Project Awards, in Part II, C,
> 2(c) for eligibility requirements. Faculty who are eligible for the
> Strengthening Award Program may wish to apply for a Standard Research
> Project Award. Applications should be directed to appropriate research
> programs, described in Part II, E., by applicable deadlines. To submit
> a Strengthening Standard Research Project Awards application, follow
> the guidelines for Integrated and Standard Research Grant Applications
> (Part IV, B., 1.), noting the following differences:
>
> \(a\) **[R&R Other Project Information]{.underline}**

-   *Field 7. Project Narrative* (formerly Project Description) -- **PDF
    Attachment. 18-Page Limit.** Title the attachment as 'Project
    Narrative' in the document header [and]{.underline} save file as
    'Project Narrative'.

> **PLEASE NOTE: For Strengthening Standard Research Project
> Applications, the Project Narrative section may not exceed a total of
> 18 single- or double-spaced pages, including figures and tables.**
> These page limitations apply regardless of whether figures or tables
> are included. All pages, including those with figures and tables,
> should be numbered sequentially. Applications exceeding the applicable
> page limitation will be returned without review. The page limit has
> been established to ensure fair and equitable competition.
>
> \(b\) **[Supplemental Information Form]{.underline}**
>
> **IMPORTANT -** *Field 8. Conflict of Interest* List -- **PDF
> Attachment. No Page Limit.** Title the attachment as 'Conflict of
> Interest' in the document header [and]{.underline} save file as
> 'Conflict of Interest'.
>
> **[A Conflict of Interest List is required for all applications
> submitted to the NRI. The Conflict of Interest List should be provided
> as a separate PDF attachment and not included in the vitae or
> resume.]{.underline}**
>
> A suggested template for the Conflict of Interest List can be found
> at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>.
>
> A Conflict of Interest List [must]{.underline} be provided for all
> individuals who have submitted a Biographical Sketch in response to
> item d., (1) of this section.
>
> \(c\) **[NRI Proposal Type Form]{.underline}**
>
> Information related to the questions on this form is dealt with in
> detail in Part VI, 2. of the CSREES Grants.gov Application Guide.

-   *Field 1. Proposal Type* -- For Strengthening Standard Research
    Project Award Applications, select "Research Project Proposal,"
    "Agricultural Research Enhancement Award (AREA)," "Strengthening,"
    and "Standard Strengthening."

## C. Submission Dates and Time

Electronic applications must be submitted by Grants.gov by COB (5:00 P.M
Eastern Time, not local time) on the dates indicated in the TABLE 5 NRI
PROGRAM DEADLINE DATES at the end of this RFA. Applications received
after applicable deadlines (5:00 P.M Eastern Time, not local time) will
be returned without review.

## D. Funding Restrictions 

For FY 2007, sections 101 (a) and (c) of the Revised Continuing
Appropriation Resolutions, 2007 (Pub. L. 110-5), limited indirect costs
to 20 percent of the total Federal funds provided under each award.
CSREES anticipates that the FY 2008 Appropriations Act will include a
similar limitation. Therefore, when preparing budgets (including
subcontract budgets), applicants should limit their requests for
recovery of indirect costs to the lesser of their institution's official
negotiated indirect cost rate or the equivalent of 20 percent of total
Federal funds awarded. Another method of calculating the maximum
allowable is 25 percent of the total direct costs. Please note that if
the 2008 Appropriations Act contains a different indirect cost
limitation CSREES will contact each successful applicant to apply the
correct rate prior to the award of a grant.

Funds may not be used for the renovation or refurbishment of research
spaces (including energy retrofitting); purchase or installations of
fixed equipment in such spaces; or planning, repair, rehabilitation,
acquisition, or construction of buildings or facilities.

## E. Other Submission Requirements

**1. Submission and Receipt of Applications**

> Applications must be submitted electronically via Grants.gov. The
> applicant should follow the submission requirements noted in "CSREES
> Grants.gov Application Guide: A Guide for Preparation and Submission
> of CSREES Applications via Grants.gov" and the additional information
> provided in this RFA. **Note instructions in this RFA supersede those
> in the CSREES Grants.gov Application Guide.**
>
> The receipt of all applications will be acknowledged by e-mail (see
> Section A. of this Part for description of the four e-mails that will
> acknowledge receipt). Therefore, applicants are strongly encouraged to
> provide accurate e-mail addresses where designated.
>
> **If an applicant has not received within 30 days of the submission an
> e-mail either providing a CSREES application number (i.e. 2008-XXXXX)
> or indicating the application was not accepted for review, the
> applicant must contact the agency contact (see Part VII) immediately
> and ask for the status of the application. Failure to do so may result
> in the application not being considered for funding by the peer review
> panel.** Once the application has been assigned an application number,
> this number should be cited on all future correspondence.

**2. Multiple Submissions**

> See Part III, 5. of "[CSREES Grants.gov Application Guide: A Guide for
> Preparation and Submission of CSREES Applications via
> Grants.gov.](http://www.csrees.usda.gov/funding/grant_forms/electronic_app_guide.pdf)"
> Duplicate, essentially duplicate, or predominantly overlapping
> applications submitted to one or more program areas within the NRI
> (including the programs described under Agricultural Research
> Enhancement Awards) in any one fiscal year **will be returned without
> review**. In addition, applicants also may not submit to the NRI an
> application that is considered duplicate, essentially duplicate, or
> predominantly overlapping with an application submitted to another
> CSREES program in the same fiscal year.

# PART V---APPLICATION REVIEW REQUIREMENTS 

# 

## A. General 

Each application will be evaluated in a two-part process. First, each
application will be screened to ensure that it meets the administrative
requirements as set forth in this RFA. **Applications that do not fall
within the guidelines, as stated in the RFA, will be eliminated from
program competition and will be returned to the applicant without
review.** Second, a review panel will technically evaluate applications
that meet these requirements. In addition to the review panel, written
comments will be solicited from *ad hoc* reviewers when necessary. Prior
to recommending an application for funding, the peer review panel and
*ad hoc* reviewer comments will be presented and discussed.

Reviewers will be selected based upon their training and experience in
relevant scientific, extension, or education fields, taking into account
the following factors: (a) the level of relevant formal scientific,
technical education, or extension experience of the individual, as well
as the extent to which an individual is engaged in relevant research,
education, or extension projects; (b) the need to include as reviewers
experts from various areas of specialization within relevant scientific,
education, or extension fields; (c) the need to include as reviewers
other experts (e.g. producers, range or forest managers/operators, and
consumers) who can assess relevance of the applications to targeted
audiences and to program needs; (d) the need to include as reviewers
experts from a variety of organizational types (e.g. colleges,
universities, industry, state and Federal agencies, private profit, and
non-profit organizations) and geographic locations; (e) the need to
maintain a balanced composition of reviewers with regard to minority and
female representation and an equitable age distribution; and (f) the
need to include reviewers who can judge the effective usefulness to
producers and the general public of each application.

## B. Evaluation Criteria 

Projects supported under this program shall be designed, among other
things, to accomplish one or more of the purposes of agriculture
research, education, and extension, subject to the varying conditions
and needs of States. Therefore, in carrying out its review, the peer
review panel shall take into account the following factors.

**[Applications for Research, Including Standard Research, Strengthening
Standard Research, Postdoctoral Fellowship, and New
Investigator:]{.underline}**

**1. Scientific Merit of the Application for Research**

> \(a\) Novelty, innovation, uniqueness, and originality;
>
> \(b\) Where model systems are used, ability to transfer knowledge
> gained from these systems to organisms of importance to U.S.
> agriculture;
>
> \(c\) Conceptual adequacy of the research, as applicable;
>
> \(d\) Clarity and delineation of objectives;
>
> \(e\) Adequacy of the description of the undertaking and suitability
> and feasibility of methodology;
>
> \(f\) Demonstration of feasibility through preliminary data and/or,
> for postdoctoral fellowships, publication record of the mentor; and
>
> \(g\) Probability of success of the project is appropriate given the
> level of scientific originality, and risk-reward balance.

**2. Qualifications of Project Personnel, Adequacy of Facilities, and
Project Management**

> \(a\) Qualifications of applicant (individual or team) to conduct the
> proposed project, including performance record and potential for
> future accomplishments (for Postdoctoral Fellowship applications, this
> applies to the mentor, as well as to the postdoctoral applicant);
>
> \(b\) Demonstrated awareness of previous and alternative approaches to
> the problem identified in the application;
>
> \(c\) Institutional experience and competence in subject area;
>
> \(d\) Adequacy of available or obtainable support personnel,
> facilities, and instrumentation; and
>
> \(e\) Planning and administration of the proposed project, including:
> time allocated for systematic attainment of objectives; and
> **planned** administration of the proposed project and its
> maintenance, partnerships, collaborative efforts, and the planned
> dissemination of information for multi-institutional projects over the
> duration of the project.

**3. Project Relevance**

a.  Documentation that the research is directed toward specific priority
    areas identified for the program in this RFA. These priorities are
    designed to yield improvements in and sustainability of U.S.
    agriculture, the environment, human health and well-being, and rural
    communities.

**Applications for a Postdoctoral Fellowship** will also be evaluated on
the quality of the training environment, including:

> \(a\) Documentation that arrangements have been made with an
> established investigator to serve as mentor; 
>
> \(b\) Documentation that arrangements have been made for the necessary
> facilities, space, and materials to conduct the proposed research; and
>
> \(c\) Potential for the postdoctoral fellow to initiate an independent
> research program.

**[For Conference Applications:]{.underline}**

**1. Relevance of the Proposed Conference to Agriculture and Food
Systems in the U.S. and Appropriateness of the Conference in Fostering
Scientific Exchange;**

**2. Qualifications of the Organizing Committee and Appropriateness of
Invited Speakers to Topic Areas Being Covered;**

**3. Uniqueness and Timeliness of the Conference; and**

**4. Appropriateness of Budget Request.**

**[Applications for Research Career Enhancement Awards, Equipment
Grants, and Seed Grants:]{.underline}**

**1. The Merit of the Proposed Activities or Research Equipment as a
Means of Enhancing the Research Capabilities and Competitiveness of the
Applicant and/or Institution;**

**2. The Applicant\'s Previous Research Experience and Background;**

**3. The Appropriateness of the Proposed Activities or Research
Equipment for the Goals Proposed; and**

**4. Relevance of the Project to Long-Range Improvements in and
Sustainability of U.S. Agriculture, the Environment, Human Health and
Well-being, and Rural Communities.**

**[Applications for Integrated Projects:]{.underline}**

These evaluation criteria should be used for the review of all
integrated research, education, and extension applications.

**1. Merit of the Application for Science Research, Education, and/or
Extension**

(a) Project objectives and outcomes are clearly described, adequate, and
    appropriate. All project components (i.e., research, education,
    extension)\--at least two are required\--are reflected in one or
    more project objectives;

(b) Proposed approach, procedures, or methodologies are innovative,
    original, clearly described, suitable, and feasible;

(c) Expected results or outcomes are clearly stated, measurable, and
    achievable within the allotted time frame;

(d) Proposed research fills knowledge gaps that are critical to the
    development of practices and programs to address the stated problem
    or issue;

(e) Proposed extension leads to measurable, documented changes in
    learning, actions, or conditions in an identified audience or
    stakeholder group; and

(f) Proposed education (teaching) has an impact upon and advances the
    quality of food and agricultural sciences by strengthening
    institutional capacities and curricula to meet clearly delineated
    needs and train the next generation of scientists and educators.

**2. Qualifications of Project Personnel, Adequacy of Facilities, and
Project Management**

(a) Roles of key personnel are clearly defined;

(b) Key personnel have sufficient expertise to complete the proposed
    project, and where appropriate, partnerships with other disciplines
    (e.g., social science or economics) and institutions are
    established;

(c) Evidence of institutional capacity and competence in the proposed
    area of work is provided;

(d) Support personnel, facilities, and instrumentation are sufficient;

(e) A clear plan is articulated for project management, including time
    allocated for attainment of objectives and delivery of products,
    maintenance of partnerships and collaborations, and a strategy to
    enhance communication, data sharing, and reporting among members of
    the project team; and

(f) The budget clearly allocates sufficient resources to carry out a set
    of research, education (teaching), and/or extension activities that
    will lead to desired outcomes, with no more than two-thirds of the
    budget focused on a single project component.

**3. Project Relevance**

(a) The project addresses a stated program priority.

(b) Project components (research, education, and/or extension)---at
    least two are required---are fully integrated and necessary to
    address the problem or issue;

(c) The proposed work addresses identified stakeholder needs;

(d) Stakeholder involvement in project development, implementation, and
    evaluation is demonstrated, where appropriate;

(e) Plan and methods for evaluating success of project activities and
    documenting potential impact against measurable short and mid-term
    outcomes are suitable and feasible;

(f) For extension or education (teaching) activities, curricula and
    related products will sustain education or extension functions
    beyond the life of the project; and

(g) For extension or education (teaching) activities, the resulting
    curricula or products share information and recommendations based on
    knowledge and conclusions from a broad range of research
    initiatives.

## 

## C. Conflicts of Interest and Confidentiality 

During the peer evaluation process, extreme care will be taken to
prevent any actual or perceived conflicts of interest that may impact
review or evaluation. For the purpose of determining conflicts of
interest, the academic and administrative autonomy of an institution
shall be determined by reference to the current Higher Education
Directory, published by Higher Education Publications, Inc., 6400
Arlington Boulevard, Suite 648, Falls Church, VA 22042. Phone: (703)
532-2300. Web site: [http://www.hepinc.com](http://www.hepinc.com/).

Names of submitting institutions and individuals, as well as application
content and peer evaluations, will be kept confidential, except to those
involved in the review process, to the extent permitted by law. In
addition, the identities of peer reviewers will remain confidential
throughout the entire review process. Therefore, the names of the
reviewers will not be released to applicants.

## 

## D. Organizational Management Information 

Specific management information relating to an applicant shall be
submitted on a one-time basis as part of the responsibility
determination prior to the award of a grant identified under this RFA,
if such information has not been provided previously under this or
another CSREES program. CSREES will provide copies of forms recommended
for use in fulfilling these requirements as part of the pre-award
process. Although an applicant may be eligible based on its status as
one of these entities, there are factors that may exclude an applicant
from receiving Federal financial and nonfinancial assistance and
benefits under this program (e.g. debarment or suspension of an
individual involved or a determination that an applicant is not
responsible based on submitted organizational management information).

#  

# PART VI---AWARD ADMINISTRATION 

## A. General 

Within the limit of funds available for such purpose, the awarding
official of CSREES shall make grants to those responsible, eligible
applicants whose applications are judged most meritorious under the
procedures set forth in this RFA. Note that the project need not be
initiated on the grant effective date, but as soon thereafter as
practical so that project goals may be attained within the funded
project period. All funds granted by CSREES under this RFA shall be
expended solely for the purpose for which the funds are granted in
accordance with the approved application and budget, the regulations,
the terms and conditions of the award, the applicable Federal cost
principles, and the applicable Department's assistance regulations (e.g.
parts 3015 and 3019 of 7 CFR). The total period for which a grant is
awarded, including all funded and no-cost time extensions, may not
exceed 5 years.

## 

## 

## B. Award Notice 

The award document will provide pertinent instructions and information
shall include at a minimum the following:

1\. Legal name and address of performing organization or institution to
which the Administrator has awarded a grant under the terms of this RFA;

2\. Title of project;

3\. Name(s) and institution(s) of PDs chosen to direct and control
approved projects;

4\. Identifying grant number assigned by the Department;

5\. Project period, specifying the amount of time the Department intends
to support the project without requiring recompetition for funds;

6\. Total amount of Departmental financial assistance approved by the
Administrator during the project period;

7\. Legal authority(ies) under which the grant is awarded;

8\. Appropriate Catalog of Federal Domestic Assistance (CFDA) number; 

9\. Applicable award terms and conditions (see
<http://www.csrees.usda.gov/business/awards/awardterms.html> to view
CSREES award terms and conditions);

10\. Approved budget plan for categorizing allocable project funds to
accomplish the stated purpose of the grant award; and

11\. Other information or provisions deemed necessary by CSREES to carry
out its respective granting activities or to accomplish the purpose of a
particular grant.

## 

## C. Administrative and National Policy Requirements 

Several Federal statutes and regulations apply to grant applications
considered for review and to project grants awarded under this program.
These include, but are not limited to:

7 CFR Part 1, subpart A---USDA implementation of the Freedom of
Information Act.

7 CFR Part 3---USDA debt collection regulations.

7 CFR Part 15, subpart A---USDA implementation of Title VI of the Civil
Rights Act of 1964, as amended.

7 CFR Part 331 and 9 CFR Part 121---USDA implementation of the
Agricultural Bioterrorism Protection Act of 2002.

7 CFR Part 3015---USDA Uniform Federal Assistance Regulations,
implementing OMB directives (i.e. OMB Circular Nos. A-21 and A-122) and
incorporating provisions of 31 U.S.C. 6301-6308 (formerly the Federal
Grant and Cooperative Agreement Act of 1977, Pub. L. No. 95-224), as
well as general policy requirements applicable to recipients of
Departmental financial assistance.

7 CFR Part 3017---USDA implementation of Government wide Debarment and
Suspension (Nonprocurement) and Government wide Requirements for
Drug-Free Workplace (Grants).

7 CFR Part 3018---USDA implementation of Restrictions on Lobbying.
Imposes prohibitions and requirements for disclosure and certification
related to lobbying on recipients of Federal contracts, grants,
cooperative agreements, and loans.

7 CFR Part 3019---USDA implementation of OMB Circular No. A-110, Uniform
Administrative Requirements for Grants and Other Agreements with
Institutions of Higher Education, Hospitals, and Other Nonprofit
Organizations.

7 CFR Part 3052---USDA implementation of OMB Circular No. A-133, Audits
of States, Local Governments, and Non-profit Organizations.

7 CFR Part 3407---CSREES procedures to implement the National
Environmental Policy Act of 1969, as amended.

29 U.S.C. 794 (section 504, Rehabilitation Act of 1973) and 7 CFR Part
15b (USDA implementation of statute)---prohibiting discrimination based
upon physical or mental handicap in Federally assisted programs.

35 U.S.C. 200 et seq.---Bayh-Dole Act, controlling allocation of rights
to inventions made by employees of small business firms and domestic
nonprofit organizations, including universities, in Federally assisted
programs (implementing regulations are contained in 37 CFR Part 401).

## 

## D. Expected Program Outputs and Reporting Requirements 

Grantees are required to submit annual and summary evaluation reports
via the CSREES Current Research Information System (CRIS). CRIS is an
electronic, Web-based inventory system that facilitates both grantee
submissions of project outcomes and public access to information on
Federally-funded projects. It can be accessed at
http://cris.csrees.usda.gov/.

If a project is funded, beginning in the first year of funding, the
project director will be required to attend annual investigator
meetings. Reasonable travel expenses should be included as part of the
project budget.

# PART VII---AGENCY CONTACTS 

# 

Applicants and other interested parties are encouraged to contact the
NRI: 

Telephone: (202) 401-5022;

fax, (202) 401-6488;

e-mail, <nricgp@csrees.usda.gov> .

Specific questions pertaining to technical matters may be directed to
the appropriate National Program Leader listed in the directory at the
end of the document.

# 

# PART VIII---OTHER INFORMATION 

# 

## A. Access to Review Information 

Copies of reviews, excluding the identity of reviewers, and a summary of
the panel comments will be sent to the applicant PD after the review
process has been completed.

## 

## B. Use of Funds; Changes 

**1. Delegation of Fiscal Responsibility**

Unless the terms and conditions of the grant state otherwise, the
grantee may not, in whole or in part, delegate or transfer to another
person, institution, or organization the responsibility for use or
expenditure of grant funds.

**2. Changes in Project Plans**

> \(a\) The permissible changes by the grantee, PD(s), or other key
> project personnel in the approved project grant shall be limited to
> changes in methodology, techniques, or other similar aspects of the
> project to expedite achievement of the project\'s approved goals. If
> the grantee or the PD(s) is uncertain as to whether a change complies
> with this provision, the question must be referred to the Authorized
> Departmental Officer (ADO) for a final determination. The ADO is the
> signatory of the award document, not the program contact.
>
> \(b\) Changes in approved goals or objectives shall be requested by
> the grantee and approved in writing by the ADO prior to effecting such
> changes. In no event shall requests for such changes be approved which
> are outside the scope of the original approved project.
>
> \(c\) Changes in approved project leadership or the replacement or
> reassignment of other key project personnel shall be requested by the
> grantee and approved in writing by the ADO prior to effecting such
> changes.
>
> \(d\) Transfers of actual performance of the substantive programmatic
> work in whole or in part and provisions for payment of funds, whether
> or not Federal funds are involved, shall be requested by the grantee
> and approved in writing by the ADO prior to effecting such transfers,
> unless prescribed otherwise in the terms and conditions of the grant.
>
> \(e\) Changes in Project Period: The project period may be extended by
> CSREES without additional financial support, for such additional
> period(s) as the ADO determines may be necessary to complete or
> fulfill the purposes of an approved project, but in no case shall the
> total project period exceed five years. Any extension of time shall be
> conditioned upon prior request by the grantee and approval in writing
> by the ADO, unless prescribed otherwise in the terms and conditions of
> a grant.
>
> \(f\) Changes in Approved Budget: Changes in an approved budget must
> be requested by the grantee and approved in writing by the ADO prior
> to instituting such changes if the revision will involve transfers or
> expenditures of amounts requiring prior approval as set forth in the
> applicable Federal cost principles, Departmental regulations, or grant
> award.

## C. Confidential Aspects of Applications and Awards 

When an application results in a grant, it becomes a part of the record
of CSREES transactions, available to the public upon specific request.
Information that the Secretary determines to be of a confidential,
privileged, or proprietary nature will be held in confidence to the
extent permitted by law. Therefore, any information that the applicant
wishes to have considered as confidential, privileged, or proprietary
should be clearly marked within the application. Such an application
will be released only with the consent of the applicant or to the extent
required by law. The original copy of an application that does not
result in a grant will be retained by the Agency for a period of three
years. Other copies will be destroyed. An application may be withdrawn
at any time prior to the final action thereon.

## 

## D. Regulatory Information 

For the reasons set forth in the final Rule-related Notice to 7 CFR part
3015, subpart V (48 FR 29114, June 24, 1983), this program is excluded
from the scope of the Executive Order 12372 which requires
intergovernmental consultation with State and local officials. Under the
provisions of the Paperwork Reduction Act of 1995 (44 U.S.C. chapter
35), the collections of information requirements contained in this
Notice have been approved under OMB Document No. 0524-0039.

## 

## E. Application Disposition 

When each peer review panel has completed its deliberations, the
responsible program staff of the NRI will recommend that the project: 
(a) be approved for support from currently available funds or (b) be
declined due to insufficient funds or unfavorable review.

The NRI reserves the right to negotiate with the PD and/or with the
submitting organization or institution regarding project revisions (e.g.
reductions in the scope of work, funding level, period, or method of
support) prior to recommending any project for funding.

An application may be withdrawn at any time before a final funding
decision is made regarding the application; however, withdrawn
applications normally will not be returned. One copy of each application
that is not selected for funding, including those that are withdrawn,
will be retained by the NRI for a period of three years. The remaining
copies will be destroyed.

## 

## 

## F. Materials Available on the Internet 

The following are among the materials available on the NRI page
(<http://www.csrees.usda.gov/funding/nri/nri.html>).

1\. NRI 2008 Request for Applications

2\. NRI Abstracts of Funded Research and Integrated Projects

3\. NRI Annual Reports

## 

## 

## G. Electronic Subscription to NRI Announcements

If you would like to receive notifications of all new announcements
pertaining to the NRI RFA, you can register via Grants.gov at
<http://www.grants.gov/search/subscribeAdvanced.do>.

-   Enter the e-mail address at which you would like to receive the
    announcements

-   Enter "10.206" for *CFDA Number*

-   Select "Subscribe to Mailing List"

Other criteria may be selected; however, your e-mail address and the
CFDA number are the only data required to receive NRI announcements. You
do not need to be a registered user of Grants.gov to use this service.
You may modify your email subscriptions or unsubscribe at any time.

## H. Definitions 

For the purpose of this program, the following definitions are
applicable:

*Administrator* means the Administrator of the Cooperative State
Research, Education, and Extension Service (CSREES) and any other
officer or employee of the Department to whom the authority involved is
delegated.

*Authorized departmental officer* means the Secretary or any employee of
the Department who has the authority to issue or modify grant
instruments on behalf of the Secretary.

*Authorized organizational representative* means the president,
director, or chief executive officer or other designated official of the
applicant organization who has the authority to commit the resources of
the organization.

*Department* or *USDA* means the United States Department of
Agriculture.

*Education Activity* means formal classroom instruction, laboratory
instruction, and practicum experience in the food and agricultural
sciences and other related matters such as faculty development, student
recruitment and services, curriculum development, instructional
materials and equipment, and innovative teaching methodologies.

*Extension Activity* means an act or process that delivers science-based
knowledge and informal educational programs to people outside of the
traditional classroom, enabling them to make more informed practical
decisions.

*Fundamental research* is research that tests scientific hypotheses and
provides basic knowledge that enables advances in applied research and
from which major conceptual breakthroughs are expected to occur.

*Grant* means the award by the Secretary of funds to an eligible
organization or individual to assist in meeting the costs of conducting,
for the benefit of the public, an identified project that is intended
and designed to accomplish the purpose of the program as identified in
these guidelines.

*Grantee* means an organization designated in the grant award document
as the responsible legal entity to which a grant is awarded.

*Integrated* means to bring together two or more of the three components
of the agricultural knowledge system (research, education, and
extension) together around a problem area or issue.

*Matching* means that portion of allowable project costs not borne by
the Federal Government, including the value of in-kind contributions.

*Minority* means Alaskan Native, American Indian, Asian-American,
African-American, Hispanic American, Native Hawaiian, or Pacific
Islander. The Secretary will determine on a case-by-case basis whether
additional groups qualify under this definition, either at the
Secretary's initiative, or in response to a written request with
supporting explanation (see Part III, B.).

*Minority-serving institution* means an academic institution whose
enrollment of a single minority or a combination of minorities, as
defined in this section, exceeds fifty percent of the total enrollment,
including graduate and undergraduate applied research and full- and
part-time students. (Applicants applying under this category should
indicate the current total enrollment of the institution in a cover
letter). An institution in this instance is an organization that
possesses a significant degree of autonomy. Significant degree of
autonomy is defined by being independently accredited as determined by
reference to the current version of the *Higher Education Directory*,
published by Higher Education Publications, Inc., 6400 Arlington
Boulevard, Suite 648, Falls Church, Virginia 22042. (703-532-2300).

*Mission-Linked Research* is research on specifically identified
agricultural problems which, through a continuum of efforts, provides
information and technology that may be transferred to users and may
relate to a product, practice or process.

*Multidisciplinary project* means research, education and extension
projects in which investigators from two or more disciplines are
collaborating closely. These collaborations, where appropriate, may
integrate the biological, physical, chemical, or social sciences.

*Peer review* means an evaluation of a proposed project for scientific
or technical quality and relevance performed by experts with the
scientific knowledge and technical skills to conduct the proposed work
or to give expert advice on the merits of an application.

*Prior approval* means written approval evidencing prior consent by an
authorized departmental officer, as defined above.

*Project* means the particular activity within the scope of the program
supported by a grant award.

*Project director* means the single individual designated in the grant
application and approved by the Secretary who is responsible for the
direction and management of the project.

*Project period* means the period, as stated in the award document,
during which Federal sponsorship begins and ends.

*Research activity* means a scientific investigation or inquiry which
results in the generation of knowledge.

*Secretary* means the Secretary of Agriculture and any other officer or
employee of the Department to whom the authority involved is delegated.

*Small and mid-sized institutions* **for Integrated Projects** are
academic institutions with a current total enrollment of 15,000 or less
including graduate and undergraduate and full- and part-time students
and that are no higher than the 50^th^ percentile of academic
institutions funded by the NRI Program in the past three years and are
not within the top 100 Federally funded institutions (See Table 3 at the
end of this document for an alphabetical listing of the most successful
institutions). Applicants applying under this category should indicate
the current total enrollment of the institution in a cover letter. An
institution, in this instance, is an organization that possesses a
significant degree of autonomy. Significant degree of autonomy is
defined by being independently accredited as determined by reference to
the current version of the *Higher Education Directory*, published by
Higher Education Publications, Inc., 6400 Arlington Boulevard, Suite
648, Falls Church, Virginia 22042. (703-532-2300).

*Small and mid-sized institutions* **for Research Projects** are
academic institutions with a current total enrollment of 15,000 or less
including graduate and undergraduate and full- and part-time students.
Applicants applying under this category should indicate the current
total enrollment of the institution in a cover letter. An institution,
in this instance, is an organization that possesses a significant degree
of autonomy. Significant degree of autonomy is defined by being
independently accredited as determined by reference to the current
version of the *Higher Education Directory*, published by Higher
Education Publications, Inc., 6400 Arlington Boulevard, Suite 648, Falls
Church, Virginia 22042 (703-532-2300).

## TABLE 1. Most Successful Universities and Colleges Receiving Federal Funds

## 

**Use to Determine Eligibility for Strengthening Research Awards - Most
Successful Universities and Colleges Receiving Federal Funds for Science
and Engineering Research and Development in FY 2003**

The following institutions are NOT eligible for equipment grants:

  ----------------------------------- -----------------------------------
  Baylor College of Medicine          University of California Santa
                                      Barbara

  Boston University                   University of Chicago

  Brown University                    University of Cincinnati

  California Institute of Technology  University of Colorado Boulder 

  Carnegie-Mellon University          University of Colorado Health
                                      Sciences Center

  Case Western Reserve University     University of Connecticut

  Colorado State University           University of Florida

  Columbia University                 University of Georgia

  Cornell University                  University of Hawaii Manoa

  CUNY Mount Sinai School of Medicine University of Kentucky

  Dartmouth College                   University of Illinois
                                      Urbana-Champaign

  Duke University                     University of Illinois Chicago

  Emory University                    University of Iowa

  Florida State University            University of Maryland Baltimore
                                      Prof School

  Georgetown University               University of Maryland College Park

  Georgia Institute of Technology     University of Massachusetts Amherst

  Harvard University                  University of Massachusetts Medical
                                      School Worcester

  Indiana University Purdue           University of Medicine and
  University at Indianapolis          Dentistry of New Jersey

  Iowa State University               University of Miami

  Johns Hopkins University            University of Michigan Ann Arbor

  Massachusetts Institute of          University of Minnesota Twin Cities
  Technology                          

  Medical College of Wisconsin        University of Missouri Columbia

  Medical University of South         University of New Mexico
  Carolina                            

  Michigan State University           University of North Carolina Chapel
                                      Hill

  New York University                 University of Pennsylvania

  North Carolina State University     University of Pittsburgh

  Northwestern University             University of Rochester

  Ohio State University               University of South Florida

  Oregon Health Sciences University   University of Southern California

  Oregon State University             University of Texas at Austin

  Pennsylvania State University       University of Texas Health Science
                                      Center Houston

  Princeton University                University of Texas Health Science
                                      Center San Antonio

  Purdue University                   University of Texas MD Anderson
                                      Cancer Center

  Rockefeller University              University of Texas Medical Branch
                                      Galveston

  Rutgers, The State University of    University of Texas SW Medical
  New Jersey                          Center Dallas

  Scripps Research Institute          University of Utah

  Stanford University                 University of Vermont

  State University of New York at     University of Virginia
  Stony Brook                         

  Thomas Jefferson University         University of Washington

  Tulane University                   University of Wisconsin Madison

  University Corporation for          Utah State University
  Atmospheric Research                

  University of Alabama Birmingham    Vanderbilt University

  University of Arizona               Virginia Commonwealth University

  University of California Berkeley   Wake Forest University

  University of California Davis      Washington University

  University of California Irvine     Wayne State University

  University of California Los        Woods Hole Oceanographic Institute
  Angeles                             

  University of California San Diego  Yale University

  University of California San        Yeshiva University, New York
  Francisco                           
  ----------------------------------- -----------------------------------

Based on data from the table Federal obligations for science and
engineering research and development to the 100 universities and
colleges receiving the largest amounts, ranked by total amount received:
in FY 2003 of Federal Science and Engineering Support to Universities,
Colleges, and Nonprofit Institutions (National Science Foundation).

##  

## TABLE 2. Lowest One Third of Universities and Colleges Receiving Federal Funds

**Use to Determine Eligibility for Possible Waiver of Matching Funds
Requirement for Equipment Grants -- Lowest One Third of Universities and
Colleges Receiving Federal Funds for Science and Engineering Research
and Development in FY 2002^5^**

  ------------------------------------ ----------------------------------
  Abilene Christian University         Ms-Al Sea Grant Consortium

  Adelphi College                      MT State University Northern

  Agnes Scott College                  Mt. Mercy College

  Ak Pacific University                Muhlenberg College

  Alamo Community College District All Niagara University
  Campuses                             

  Albany College Of Pharmacy           Nj City University

  Albany State University              North GA College And State
                                       University

  Albion College                       Northern Mi University

  Alderson-Broaddus College            Northland College

  Alma College                         Northwest Mo State University

  American Indian Higher Ed.           Northwestern College (Orange City,
  Consortium                           IA)

  American River College               Northwestern State University

  Andrews University                   NY Institute Of Technology All
                                       Campuses

  Angelo State University              Occidental College

  Appalachian State University         Oklahoma City Community College

  Ar Tech University                   Pacific Lutheran University

  Ashland University                   Paine College

  Assumption College                   Pasadena City College

  Augustana College (Rock Island, Il)  Paul Smith\'s College Of Arts And
                                       Sciences

  Austin College                       Philadelphia University

  Avila University                     Phoenix College

  Bank Street College Of Ed.           Pontifical Catholic University PR,
                                       The

  Beloit College                       Prince George\'s Community College

  Bentley College                      Radford University

  Berry College                        Ramapo College Nj

  Bethel College And Seminary All      Regis University
  Campuses                             

  Bethune Cookman College              Rhodes College

  Bevill State Community Collegewalker Richard Stockton College Nj
  Campus                               

  Birmingham Southern College          Rider University

  Bloomsburg University PA             Roanoke College

  Bradley University                   Rockhurst University

  Brenau University                    Rocky Mountain College

  Butler University                    Rogue Community College

  Cameron University                   Rollins College

  Canisius College                     Rose-Hulman Institute Of
                                       Technology

  Cankdeska Cikana Community College   Rust College

  Central CT State University          Salisbury University

  Central Ga Technical College         San Jacinto College

  Chaminade University Honolulu        Savannah State University

  Chapman University                   Science & Engineering Alliance,
                                       InCollege

  Chief Dull Knife College             Siena College

  City Colleges Chicago All Campuses   Simpson College (Indianola, Ia)

  Claremont Mckenna College            Sisseton-Wahpeton Community
                                       College

  Coe College                          Sistema Universitario Ana G.
                                       Mendez

  Colby College                        Sitting Bull College

  College Of Menominee Nation          Sojourner-Douglas College

  College Of St. Catherine             South Tx Community College

  College Of St. Scholastica           Southeast Mo State University

  College Of The Holy Cross            Southeastern Ok State University

  College Wooster                      Southern Ct State University

  Columbus State University            Southern IL University

  Contra Costa Community College       Southwest FL College

  Cooper Union                         Southwest Mo State University

  Coppin State College                 Southwestern Indian Polytechnic
                                       Institute

  Culture And Arts Development         Springfield College (Springfield,
                                       Ma)

  Cuny                                 St. Anselm College

  Cuny Medgar Evers College            St. Francis College (Brooklyn, Ny)

  Daytona Beach Community College      St. Joseph\'s College (North
                                       Windham, Me)

  Delta State University               St. Mary\'s College CA

  Dillard University                   St. Mary\'s University (San
                                       Antonio, Tx)

  Dowling College                      St. Norbert College

  Drake University                     St. Paul Technical College

  D\'Youville College                  St. Peter\'s College

  Earlham College And Earlham School   State University West Ga
  Of Religion                          

  Eastern WA University                Stephens College

  Eckerd College                       Sterling College (Craftbury
                                       Common, Vt)

  Emerson College                      Stillman College

  Emporia State University             Suny College Cortland

  Estrella Mountain Community College  Suny College Fredonia

  Evergreen State College              SUNY College Of Technology Alfred

  Fairmont State College               Suny College Oneonta

  Five Colleges, InCollege             Suny College Potsdam

  FL Gulf Coast University             Suny New Paltz

  Francis Marion University            Suny Purchase College

  Frederick Community College          Sweet Briar College

  Frostburg State University           Talladega College

  Ft. Berthold Community College       Taylor University Upland

  Ft. Hays State University            Thomas More College

  Ft. Lewis College                    Trinity College (Harford, Ct)

  GA Perimeter College                 Trinity College (Washington, Dc)

  Gallaudet University                 Tri-State University

  Gem National Consortium For Graduate Tx A&M International University
  Degrees For Minorities In            
  Engineering And Science              

  Geneva College                       Tx A&M University System Health
                                       Science Ctr.

  Gordon-Conwell Theological Seminary  Uniformed Services University Of
                                       The Health Sciences

  Goucher College                      United Tribes Technical College

  Grand Valley State University        Universidad Del Este

  Grinnell College                     Universidad Del Turabo

  Gulf Coast Ed. Initiative Consortium University Ar Monticello

  Gustavus Adolphus College            University Central Ar

  Hartwick College                     University Central Ok

  Haskell Indian Nations University    University Charleston

  Hostos Community College Cuny        University Consortium For
                                       Geographic Information Science

  Il Wesleyan University               University Detroit Mercy

  Immaculata University                University Evansville

  Indiana University PA All Campuses   University Md University College

  Institute Of American Indian And AK  University Me Farmington
  Native                               

  International American University Pr University Mt-Western, The

  Isim University                      University NC Asheville

  Jacksonville State University        University New Haven

  Jacksonville University              University Of St. Thomas (Houston,
                                       Tx)

  Jarvis Christian College             University Of The Incarnate World

  Judson College (Elgin, Il)           University Of The Sacred Heart

  Juniata College                      University Of The South

  Kettering University                 University Puget Sound

  Keuka College                        University Scranton

  Lac Courte Oreilles Ojibwa Community University Southern Co
  College                              

  Lake Forest College                  University TN Space Institute

  Lamar University                     University Wi Stevens Point

  Lane College                         University WI Stout

  Lawrence Technological University    University Wi Whitewater

  Lawson State Community College       UniversityS. Military Academy

  Le Moyne-Owen College                Va Union University

  Le Tourneau University               Valdosta State University

  Liberty University                   Wabash College

  Los Angeles Community College        Washington And Lee University

  Loyola College                       Washington County Technical
                                       College

  Loyola University Of New Orleans     West Chester University Pa

  Lubbock Christian University         West Tx A&M University

  Luther College                       Western Carolina University

  Lynchburg College                    Western New England College

  Lyon College                         Western Wi Technical College

  Ma Bay Community College             Westmont College

  Macon State College                  Wheaton College (Wheaton, Il)

  Mary Baldwin College                 Whitworth College

  Marymount College (Tarrytown, Ny)    Wi Lutheran College

  Mcdaniel College                     Widener University All Campuses

  Mcpherson College                    Wilkes University

  Medaille College                     Willamette University

  Medvance Institute                   Winona State University

  Millsaps College                     Winthrop University

  MN State Colleges & Universities     Xavier University

  MN State University Moorhead         Yavapai College
  ------------------------------------ ----------------------------------

Based on data from the table, Federal obligations for science and
engineering research and development to universities and colleges,
ranked by total amount received, by agency: FY 2002 Survey of Federal
Science and Engineering Support to Universities, Colleges, and Nonprofit
Institutions (National Science Foundation).

^5^ University-administered foundations must contact CSREES' Competitive
Programs Unit to determine their eligibility (see contact information on
p. 136).

## TABLE 3. Most Successful Universities and Colleges Receiving Federal and/or NRI Funds

**Use to Determine Eligibility for Bridge Grants-Most Successful
Universities and Colleges Receiving Federal and/or National Research
Initiative Funds**

  ---------------------------------- ------------------------------------
  Alabama A & M University\*         University of California Los Angeles

  Auburn University \*               University of California Riverside
                                     \*

  Baylor College of Medicine         University of California San Diego

  Baylor University \*               University of California San
                                     Francisco

  Boise State University \*          University of California Santa
                                     Barbara

  Boston University                  University of California Santa Cruz
                                     \*

  Brown University                   University of Chicago

  California Institute of Technology University of Cincinnati

  California State Polytechnic       University of Colorado Boulder 
  University \*                      

  Carnegie-Mellon University         University of Connecticut

  Case Western Reserve University    University of Delaware \*

  City University of New York, City  University of Florida
  College\*                          

  Clemson University \*              University of Georgia

  Colorado State University          University of Hawaii Manoa

  Columbia University                University of Idaho \*

  Cornell University                 University of Illinois Chicago

  CUNY Mount Sinai School of         University of Illinois
  Medicine                           Urbana-Champaign

  Dartmouth College                  University of Iowa

  Drew University\*                  University of Kansas

  Duke University                    University of Kentucky

  Emory University                   University of Maine Orono \*

  Florida State University           University of Maryland Baltimore
                                     Prof Sch

  Georgetown University              University of Maryland Biotechnology
                                     Institute \*

  Georgia Institute of Technology    University of Maryland College Park

  Harvard University                 University of Massachusetts Amherst
                                     \*

  Illinois State University \*       University of Massachusetts Medical
                                     School Worcester

  Indiana University Bloomington \*  University of Medicine and Dentistry
                                     of New Jersey

  Indiana University Purdue          University of Miami
  University at Indianapolis         

  Iowa State University \*           University of Michigan Ann Arbor

  Johns Hopkins University           University of Minnesota Twin Cities

  Kansas State University \*         University of Mississippi \*

  Louisiana State University \*      University of Mississippi Medical
                                     Center \*

  Loyola University Chicago \*       University of Missouri Columbia

  Massachusetts Institute of         University of Missouri Rolla \*
  Technology                         

  Medical College of Wisconsin       University of Missouri St. Louis \*

  Medical University of South        University of Montana \*
  Carolina                           

  Miami University\*                 University of Nebraska Lincoln \*

  Michigan State University          University of Nebraska Kearney \*

  Michigan Technological University  University of Nevada Las Vegas \*
  \*                                 

  Mississippi State University       University of Nevada Reno \*

  Montana State University \*        University of New Hampshire \*

  New Mexico Institute of Mining and University of New Mexico
  Technology \*                      

  New Mexico State University \*     University of North Carolina Chapel
                                     Hill

  New York University                University of North Carolina
                                     Greensboro \*

  North Carolina State University \* University of North Texas \*

  North Dakota State University \*   University of Notre Dame \*

  Northern Arizona University \*     University of Oklahoma Health
                                     Sciences Center \*

  Northwestern University            University of Oregon \*

  Ohio State University              University of Pennsylvania

  Oklahoma State University \*       University of Pittsburgh

  Oregon Health Sciences University  University of Rhode Island \*

  Oregon State University            University of Rochester

  Pennsylvania State University      University of South Florida

  Princeton University               University of Southern California

  Purdue University                  University of Tennessee Knoxville \*

  Rice University \*                 University of Texas at Austin

  Rockefeller University             University of Texas Health Science
                                     Center San Antonio

  Rutgers, The State University of   University of Texas Health Science
  New Jersey                         Center Houston

  Scripps Research Institute         University of Texas MD Anderson
                                     Cancer Center

  South Dakota State University \*   University of Texas Medical Branch
                                     Galveston

  Southern Illinois University       University of Texas SW Medical
  Carbondale \*                      Center Dallas

  Southwestern Indian Polytechnic    University of Utah
  Institute \*                       

  Stanford University                University of Vermont

  State University of New York at    University of Virginia
  Albany \*                          

  State University of New York at    University of Washington
  Stony Brook                        

  State University of New York       University of Wisconsin Madison
  College of Environmental Science & 
  Forestry \*                        

  Texas A&M University \*            University of Wyoming \*

  Texas Tech University \*           Utah State University

  Thomas Jefferson University        Vanderbilt University

  Tufts University \*                Virginia Commonwealth University

  Tulane University                  Virginia Institute of Marine Science
                                     \*

  University of Alabama Birmingham   Wake Forest University

  University of Alaska Fairbanks \*  Washington State University \*

  University of Arizona              Washington University

  University of Arkansas             Wayne State University
  Fayetteville \*                    

  University of California Berkeley  West Virginia University \*

  University of California Davis     Woods Hole Oceanographic Institute

  University of California Irvine    Yale University

                                     Yeshiva University New York
  ---------------------------------- ------------------------------------

Based on data from the table Federal obligations for science and
engineering research and development to the 100 universities and
colleges receiving the largest amounts, ranked by total amount received:
in FY 2003 of Federal Science and Engineering Support to Universities,
Colleges, and Nonprofit Institutions (National Science Foundation).

\*Annotated institutions are not in the list for the most successful
Federally funded, but were among the top 50th percentile of those funded
by the National Research Initiative (Competitive, Special, and
Facilities Research Grant Act (7 U.S.COLLEGE 450i(b)).

###  

### NRI DEADLINE DATES FOR FY 2008

The following dates have been established for FY 2008 application
submission deadlines within the NRI Program, CSREES, United States
Department of Agriculture. To be considered for funding in any fiscal
year, applications must be SUBMITTED TO Grants.gov by Close of Business
(5:00 P.M., Eastern Time) on the date listed below. When the deadline
date falls on a weekend or Federal holiday, transmission must be made by
the following business day.

In FY 2008 several programs require a letter of intent prior to
submission of the full application. Select individuals will be invited
to submit a complete application by the program's deadline. Applications
submitted to programs requiring a letter of intent without the proper
invitation will be returned without review.

Programs offered in any fiscal year depend on availability of funds and
deadlines may be delayed due to unforeseen circumstances. Consult the
NRI home page (<http://www.csrees.usda.gov/funding/nri/nri.html>) for
up-to-date information.

## TABLE 4 NRI Personnel Contact Information

+----------------------------+------------+-----------------+--------+
| Deputy Administrator       | Dr. Anna   | apalmisano@     | \      |
|                            | Palmisano  | csrees.usda.gov | (202\) |
|                            |            |                 | 40     |
|                            |            |                 | 1-1761 |
+----------------------------+------------+-----------------+--------+
| Research Director          | Dr. Mark   | mpoth@          | \      |
|                            | Poth       | csrees.usda.gov | (202\) |
|                            |            |                 | 40     |
|                            |            |                 | 1-5244 |
+----------------------------+------------+-----------------+--------+
| Integrated Programs        | Dr.        | dsheely@        | \      |
| Director                   | Deborah    | csrees.usda.gov | (202\) |
|                            | Sheely     |                 | 40     |
|                            |            |                 | 1-1924 |
+----------------------------+------------+-----------------+--------+
|                            |            |                 |        |
+----------------------------+------------+-----------------+--------+
| Extension and Education    | Dr. Elbert | edickey@        | \      |
| Advisor                    | Dickey     | csrees.usda.gov | (202\) |
|                            |            |                 | 20     |
|                            |            |                 | 5-5700 |
+----------------------------+------------+-----------------+--------+
|                            |            |                 |        |
+----------------------------+------------+-----------------+--------+
| Science Advisor            | Dr. Larry  | lrobinson@c     | \      |
|                            | Robinson   | sreesu.usda.gov | (202\) |
|                            |            |                 | 72     |
|                            |            |                 | 0-1765 |
+----------------------------+------------+-----------------+--------+
| Microbial Genomics         | Dr. Ann    | apark@          | (2     |
|                            | Li         | csrees.usda.gov | 02) 40 |
|                            | chens-Park | djones@         | 1-6460 |
|                            | Dr. Daniel | csrees.usda.gov | (202)  |
|                            | Jones      |                 | 40     |
|                            |            |                 | 1-6854 |
+----------------------------+------------+-----------------+--------+
| Microbial Biology          | Dr. John   | jsherwood@      | (2     |
|                            | L.         | csrees.usda.gov | 02) 69 |
|                            | Sherwood   | apark@          | 0-1659 |
|                            | Dr. Ann    | csrees.usda.gov | (2     |
|                            | Li         |                 | 02) 40 |
|                            | chens-Park |                 | 1-6460 |
+----------------------------+------------+-----------------+--------+
| Plant Genome               | Dr. Ed     | ekaleikau@      | (2     |
|                            | Kaleikau   | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-1931 |
+----------------------------+------------+-----------------+--------+
| Plant Biosecurity          | Dr.        | llin@           | (2     |
|                            | L          | csrees.usda.gov | 02) 40 |
|                            | iang-Shiou | jsherwood@      | 1-5042 |
|                            | Lin Dr.    | csrees.usda.gov | (2     |
|                            | John L.    |                 | 02) 69 |
|                            | Sherwood   |                 | 0-1659 |
+----------------------------+------------+-----------------+--------+
| Arthropod and Nematode     | Dr. Mary   | mpurcell@       | (2     |
| Biology and Management     | Purcell-   | csrees.usda.gov | 02) 20 |
|                            | Miramontes |                 | 5-0440 |
+----------------------------+------------+-----------------+--------+
| Animal Genome              | Dr. Peter  | pburfening@     | (2     |
|                            | Burfening  | csrees.usda.gov | 02) 40 |
|                            | Dr.        | mqureshi@       | 1-5823 |
|                            | Muquarrab  | csrees.usda.gov | (202)  |
|                            | Qureshi    |                 | 40     |
|                            |            |                 | 1-4895 |
+----------------------------+------------+-----------------+--------+
| Animal Protection and      | Dr. Peter  | pbrayton@       | (2     |
| Biosecurity                | Brayton    | csrees.usda.gov | 02) 40 |
|                            | Dr. Peter  | pjohnson@       | 1-4399 |
|                            | Johnson    | csrees.usda.gov | (2     |
|                            |            |                 | 02) 40 |
|                            |            |                 | 1-1896 |
+----------------------------+------------+-----------------+--------+
| Animal Reproduction        | Dr. Mark   | mmirando@       | (2     |
|                            | Mirando    | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-4336 |
+----------------------------+------------+-----------------+--------+
| Animal Growth and Nutrient | Dr. Mark   | mmirando@       | (2     |
| Utilization                | Mirando    | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-4336 |
+----------------------------+------------+-----------------+--------+
| Plant Biology              | Dr.        | llin@           | (2     |
|                            | L          | csrees.usda.gov | 02) 40 |
|                            | iang-Shiou | gmclean@        | 1-5042 |
|                            | Lin Dr.    | csrees.usda.gov | (2     |
|                            | Gail       |                 | 02) 40 |
|                            | McLean     |                 | 1-6060 |
+----------------------------+------------+-----------------+--------+
| Agribusiness Markets and   | Dr. Siva   | ssureshwaran@   | (2     |
| Trade                      | S          | csrees.usda.gov | 02) 72 |
|                            | ureshwaran |                 | 0-7536 |
+----------------------------+------------+-----------------+--------+
| Biobased Products and      | Dr.        | cjacobs@        | (2     |
| Bioenergy Production       | Chavonda   | csrees.usda.gov | 02) 40 |
| Research                   | Ja         |                 | 1-6188 |
|                            | cobs-Young |                 |        |
+----------------------------+------------+-----------------+--------+
| Nanoscale Science and      | Dr. Hongda | hchen@          | \      |
| Engineering for            | Chen       | csrees.usda.gov | (202\) |
| Agriculture and Food       |            |                 | 40     |
| Systems                    |            |                 | 1-6497 |
+----------------------------+------------+-----------------+--------+
|                            |            |                 |        |
+----------------------------+------------+-----------------+--------+
| Bioactive Food Components  | Dr. Etta   | esaltos@        | (2     |
| for Optimal Health         | Saltos     | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-5178 |
+----------------------------+------------+-----------------+--------+
| Human Nutrition and        | Dr. Etta   | esaltos@        | (2     |
| Obesity                    | Saltos Dr. | csrees.usda.gov | 02) 40 |
|                            | Susan      | swelsh@         | 1-5178 |
|                            | Welsh      | csrees.usda.gov | (202)  |
|                            |            |                 | 72     |
|                            |            |                 | 0-5544 |
+----------------------------+------------+-----------------+--------+
| Food Safety and            | Dr. Chris  | cwozniak@       | \      |
| Epidemiology               | Wozniak    | csrees.usda.gov | (202\) |
|                            | Dr. Mary   | mtorrence@      | 40     |
|                            | Torrence   | csrees.usda.gov | 1-6020 |
|                            |            |                 | (202)  |
|                            |            |                 | 40     |
|                            |            |                 | 1-6357 |
+----------------------------+------------+-----------------+--------+
| Improving Food Quality and | Dr. Ram    | rrao@           | \      |
| Value                      | Rao Dr.    | csrees.usda.gov | (202\) |
|                            | Hongda     | hchen@          | 40     |
|                            | Chen       | csrees.usda.gov | 1-6010 |
|                            |            |                 | (202)  |
|                            |            |                 | 40     |
|                            |            |                 | 1-6497 |
+----------------------------+------------+-----------------+--------+
| Managed Ecosystems         | Dr. Diana  | djerkins@       | (2     |
|                            | Jerkins    | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-6996 |
+----------------------------+------------+-----------------+--------+
| Soil Processes             | Dr. Nancy  | ncavallaro@     | (2     |
|                            | Cavallaro  | csrees.usda.gov | 02) 40 |
|                            |            |                 | 1-4082 |
+----------------------------+------------+-----------------+--------+
| Water and Watersheds       | Ms. Mary   | mrozum@         | \      |
|                            | Ann Rozum  | csrees.usda.gov | (202\) |
|                            |            |                 | 40     |
|                            |            |                 | 1-4533 |
+----------------------------+------------+-----------------+--------+
| Global and Climate Change  | Dr. Nancy  | ncavallaro@     | \      |
|                            | Cavallaro  | csrees.usda.gov | (202\) |
|                            | Dr. Louie  |                 | 40     |
|                            | Tupas      | ltupas@         | 1-4082 |
|                            |            | csrees.usda.gov |        |
|                            |            |                 | \      |
|                            |            |                 | (202\) |
|                            |            |                 | 40     |
|                            |            |                 | 1-4926 |
+----------------------------+------------+-----------------+--------+
| Air Quality                | Dr. Ray    | rknighton@      | \      |
|                            | Knighton   | csrees.usda.gov | (202\) |
|                            |            |                 | 40     |
|                            |            |                 | 1-6417 |
+----------------------------+------------+-----------------+--------+
| Biology of Weedy and       | Dr.        | mbowers@        | \      |
| Invasive Species in        | Michael    | csrees.usda.gov | (202\) |
| Agroecosystems             | Bowers     |                 | 40     |
|                            |            |                 | 1-4510 |
+----------------------------+------------+-----------------+--------+
| Rural Development          | Dr. Siva   | ssureshwaran@   | (2     |
|                            | S          | csrees.usda.gov | 02) 72 |
|                            | ureshwaran |                 | 0-7536 |
+----------------------------+------------+-----------------+--------+
| Agricultural Prosperity    | Dr. Siva   | ssureshwaran@   | (2     |
| for Small and Medium-Sized | S          | csrees.usda.gov | 02) 72 |
| Farms                      | ureshwaran | djerkins@       | 0-7536 |
|                            | Dr. Diana  | csrees.usda.gov | (202)  |
|                            | Jerkins    |                 | 40     |
|                            |            |                 | 1-6996 |
+----------------------------+------------+-----------------+--------+

## TABLE 5 NRI Program Deadline Date

  ---------- ---------------------------------------------------------------------------------- -------------------- ---------------- ------------ ---------------
  **Code**   **Program**                                                                        **National Program   **Integrated**   **Letter of  **Application
                                                                                                Leader**                              Intent       Deadline**
                                                                                                                                      Deadline**   

  20.2       [Plant Biosecurity^6^](#_C._Project_Types)                                         Dr. Liang-Shiou Lin  Yes              3/14/2008    6/5/2008
                                                                                                Dr. John L. Sherwood                               

  23.1       [Managed Ecosystems^7^](#managed-ecosystems)                                       Dr. Diana Jerkins    Yes              10/9/2007    12/19/2007

  25.0       [Soil Processes^8^](#soil-processes)                                               Dr. Nancy Cavallaro  No               11/19/2007   2/14/2008

  26.0       [Water and Watersheds^8^](#water-and-watersheds)                                   Ms. Mary Ann Rozum   No               No           1/17/2008

  27.0       [Global and Climate Change](#_C._Project_Types)                                    Dr. Nancy Cavallaro  No               No           not offered
                                                                                                Dr. Louie Tupas                                    

  28.0       [Air Quality^7^](#air-quality)                                                     Dr. Ray Knighton     Yes              3/5/2008     6/5/2008

  31.0       [Bioactive Food Components for Optimal                                             Dr. Etta Saltos      Yes              11/5/2007    1/17/2008
             Health^7^](#bioactive-food-components-for-optimal-health)                                                                             

  31.5       [Human Nutrition and Obesity^7^](#_31.5_Human_Nutrition_1)                         Dr. Etta Saltos Dr.  Yes              No           6/5/2008
                                                                                                Susan Welsh                                        

  32.0       [Food Safety and Epidemiology (A): Biological Approaches for Food                  Dr. Chris Wozniak    No               No           12/19/2007
             Safety^8^](#food-safety-and-epidemiology)                                                                                             

  32.0       [Food Safety and Epidemiology (B): Epidemiological Approaches for Food             Dr. Mary E. Torrence No               No           12/19/2007
             Safety^8^](#food-safety-and-epidemiology)                                                                                             

  41.0       [Animal Reproduction^7^](#_C._Project_Types)                                       Dr. Mark Mirando     Yes              No           11/15/2007

  42.0       [Animal Growth and Nutrient                                                        Dr. Mark Mirando     Yes              No           6/5/2008
             Utilization^7^](#animal-growth-and-nutrient-utilization)                                                                              

  43.0       [Animal Genome (A): Translational Animal Genomics^7^](#animal-genome)              Dr. Peter J.         Yes              3/14/2008    6/5/2008
                                                                                                Burfening Dr.                                      
                                                                                                Muquarrab Qureshi                                  

  43.0       [Animal Genome (B): Tools and Resources^8^](#animal-genome)                        Dr. Peter J.         No               No           6/5/2008
                                                                                                Burfening Dr.                                      
                                                                                                Muquarrab Qureshi                                  

  43.0       [Animal Genome (C):Bioinformatics^8^](#animal-genome)                              Dr. Peter J.         No               No           6/5/2008
                                                                                                Burfening Dr.                                      
                                                                                                Muquarrab Qureshi                                  

  43.0       [Animal Genome (D): Functional Genomics^8^](#animal-genome)                        Dr. Peter J.         No               3/14/2008    6/5/2008
                                                                                                Burfening Dr.                                      
                                                                                                Muquarrab Qureshi                                  

  43.0       [Animal Genome (E): Whole Genome Enabled Animal Selection^8^](#animal-genome)      Dr. Peter J.         No               11/26/2007   2/14/2008
                                                                                                Burfening Dr.                                      
                                                                                                Muquarrab Qureshi                                  

  44.0       [Animal Protection and Biosecurity (A): Animal                                     Dr. Peter Johnson    No               10/9/2007    12/19/2007
             Disease^8^](#animal-protection-and-biosecurity)                                    Dr. Peter Brayton                                  

  44.0       [Animal Protection and Biosecurity (B): Animal                                     Dr. Peter Brayton    Yes              No           12/19/2007
             Well-Being^7^](#animal-protection-and-biosecurity)                                                                                    

  44.0       [Animal Protection and Biosecurity (C):Animal Biosecurity                          Dr. Peter Johnson    Yes              No           12/19/2007
             CAP^6^](#animal-protection-and-biosecurity)                                                                                           

  51.0       [Microbial Genomics (A): Genome Sequencing^8^](#microbial-genomics)                Dr. Ann Lichens-Park No               No           see NSF
                                                                                                Dr. Daniel Jones                                   

  51.0       [Microbial Genomics (B): Functional Genomics of                                    Dr. Ann Lichens-Park No               No           not offered
             Microorganisms](#microbial-genomics)                                                                                                  

  51.2       [Arthropod and Nematode Biology and Management (A): Organismal and Population      Dr. Mary             No               11/26/2007   2/14/2008
             Biology^8^](#arthropod-and-nematode-biology-and-management)                        Purcell-Miramontes                                 

  51.2       [Arthropod and Nematode Biology and Management (B): Suborganismal                  Dr. Mary             No               3/14/2008    6/5/2008
             Biology^8^](#arthropod-and-nematode-biology-and-management)                        Purcell-Miramontes                                 

                                                                                                                                                   

  **Code**   **Program**                                                                        **National Program   **Integrated**   **Letter of  **Application
                                                                                                Leader**                              Intent       Deadline**
                                                                                                                                      Deadline**   

  51.2       [Arthropod and Nematode Biology and Management (C): Tools, Resources, and          Dr. Mary             No               314/2008     6/5/2008
             Genomics^8^](#arthropod-and-nematode-biology-and-management)                       Purcell-Miramontes                                 

  51.2       [Arthropod and Nematode Biology and Management (D): Protection of Managed Bees     Dr. Mary             Yes              11/26/2007   2/14/2008
             CAP^6^](#arthropod-and-nematode-biology-and-management)                            Purcell-Miramontes                                 

  51.8       [Microbial Biology (A): Microbial Observatories^8^](#microbial-biology)            Dr. John Sherwood    No               No           see NSF

  51.8       [Microbial Biology (B): Microbial Associations with Plants^8^](#microbial-biology) Dr. Ann Lichens-Park No               10/9/2007    12/19/2007

  51.9       [Biology of Weedy and Invasive Species in                                          Dr. Michael Bowers   Yes              12/6/2007    3/5/2008
             Agroecosystems^7^](#biology-of-weedy-and-invasive-species-in-agroecosystems)                                                          

  52.1       [Plant Genome (A): Tools, Resources, and Bioinformatics^8^](#_C._Project_Types)    Dr. Ed Kaleikau      No               No           2/14/2008

  52.1       [Plant Genome (B): Functional Genomics^8^](#_C._Project_Types)                     Dr. Ed Kaleikau      No               No           2/14/2008

  52.1       [Plant Genome (C):Genome Structure and Organization^8^](#_C._Project_Types)        Dr. Ed Kaleikau      No               No           2/14/2008

  52.1       [Plant Genome (D): Applied Plant Genomics CAP^6^](#_C._Project_Types)              Dr. Ed Kaleikau      Yes              11/26/2007   2/14/2008

  56.0       [Plant Biology (A): Gene Function and Regulation^8^](#_56.0_Plant_Biology:)        Dr. Liang-Shiou Lin  No               10/9/2007    12/19/2007

  56.0       [Plant Biology (B): Environmental Stress^8^](#_56.0_Plant_Biology:)                Dr. Gail McLean      No               10/9/2007    12/19/2007

  56.0       [Plant Biology (C): Biochemistry^8^](#_56.0_Plant_Biology:)                        Dr. Gail McLean      No               11/26/2007   2/14/2008

  56.0       [Plant Biology (D): Growth and Development^8^](#_56.0_Plant_Biology:)              Dr. Liang-Shiou Lin  No               11/26/2007   2/14/2008

  56.0       [Plant Biology (E): Plant Breeding and Education^6^](#_56.0_Plant_Biology:)        Dr. Liang-Shiou Lin  Yes              10/9/2007    12/19/2007
                                                                                                Dr. Gail McLean                                    

  61.0       [Agribusiness Markets and Trade](#_C._Project_Types)                               Dr. Siva Sureshwaran No               No           not offered

  62.0       [Rural Development^6^](#rural-development)                                         Dr. Siva Sureshwaran Yes              No           2/14/2008

  66.0       [Agricultural Prosperity for Small and Medium-Sized Farms^6^](#_C._Project_Types)  Dr. Siva Sureshwaran Yes              No           6/5/2008
                                                                                                Dr. Diana Jerkins                                  

  71.1       [Improving Food Quality and Value^7^](#_C._Project_Types)                          Dr. Ram Rao          Yes              11/5/2007    1/17/2008

  71.2       [Biobased Products and Bioenergy Production                                        Dr. Chavonda         No               11/2/2007    1/17/2008
             Research^8^](#biobased-products-and-bioenergy-production-research)                 Jacobs-Young                                       

  75.0       [Nanoscale Science and Engineering for Agriculture and Food                        Dr. Hongda Chen      No               No           1/17/2008
             Systems^8^](#nanoscale-science-and-engineering-for-agriculture-and-food-systems)                                                      
  ---------- ---------------------------------------------------------------------------------- -------------------- ---------------- ------------ ---------------

## 

## ^6^ This program only solicits integrated projects.

## ^7^ This program solicits integrated and research projects.

## ^8^ This program only solicits research projects. 

## FIGURE 1. Flow Chart for Strengthening Research Award Eligibility 

## 

(Seed Grants, Research Career Enhancement Awards, Strengthening Standard
Awards; **NOT Equipment Grants\***)

  --- --- ---------- -- ---------- ----------------- --- ------------- -- ---- -------------- --- --- ----- ---------- --- ---------- --- -- ---------- --
                                   Do you have an                                                                                                       
                                   appointment at a                                                                                                     
                                   degree-granting                                                                                                      
                                   institution?                                                                                                         

                                                                                                                                                        

                                   Yes                                                                      No                                          

                                                                                                                                                        

                                                                                                                                                        

          Are you                                                                                           Not                                         
          eligible                                                                                          Eligible                                    
          for EPSCoR                                                                                                                                    
          Funds?                                                                                                                                        

                                                                                                                                                        

          Yes                                                             No                                                                            

                                                                                                                                                        

          Eligible                                       Is the                                                                                         
                                                         current                                                                                        
                                                         enrollment of                                                                                  
                                                         your                                                                                           
                                                         institution                                                                                    
                                                         \< 15,000?                                                                                     

                                                                                                                                                        

                                   No                                                                 Yes                                               

                                                                                                                                                        

                                                                                                                                                        

                        Not                                                    Is your                                                                  
                        Eligible                                               institution                                                              
                                                                               among the most                                                           
                                                                               successful                                                               
                                                                               institutions                                                             
                                                                               (see Table 1)?                                                           

                                                                                                                                                        

                                                                               Yes                                         No                           

                                                                                                                                                        

                                                                               Not Eligible                                Eligible                     
  --- --- ---------- -- ---------- ----------------- --- ------------- -- ---- -------------- --- --- ----- ---------- --- ---------- --- -- ---------- --

\*The only requirements for Equipment Grants are that the institution is
degree granting and not among the Most Successful Universities and
Colleges (see Table 1).

## FIGURE 2. Flow Chart for Bridge Grant Eligibility

## 

  --- -- --------------- -- --- -- -- -- -- -- -- -- ------------------ -- -- -- -- -- -- -- -- ---------- ---- -- -- -- -- -- -- -- -- -- -- -- -- --------------- ---------- -- -- ----- -- -- -- -- ---- -- -- -- -- -- -- -- -- -- ------------- ---------- -- -- ----- ---- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- ---------- ---- -- -- -- -- -- -- -- -- --
                                                     Is your                                                                                                                                                                                                                                                                                                          
                                                     institution a                                                                                                                                                                                                                                                                                                    
                                                     minority-serving                                                                                                                                                                                                                                                                                                 
                                                     institution (see                                                                                                                                                                                                                                                                                                 
                                                     definition in Part                                                                                                                                                                                                                                                                                               
                                                     VIII. H.)?                                                                                                                                                                                                                                                                                                       

                                                                                                                                                                                                                                                                                                                                                                      

                                                     Yes                                                                                                                                               No                                                                                                                                                             

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                                                                                                                                      

         Is your                                                                                                                                                                                                                       Is your                                                                                                                        
         institution                                                                                                                                                                                                                   institution                                                                                                                    
         among the most                                                                                                                                                                                                                small- or                                                                                                                      
         successful                                                                                                                                                                                                                    mid-sized                                                                                                                      
         institutions?                                                                                                                                                                                                                 (total                                                                                                                         
         (See Table 3)                                                                                                                                                                                                                 enrollment                                                                                                                     
                                                                                                                                                                                                                                       \<15,000)?                                                                                                                     

                                                                                                                                                                                                                                                                                                                                                                      

         Yes                                                                                               No                                                                                                                                                         Yes                                                                No                           

                                                                                                                                                                                                                                                                                                                                                                      

         Not Eligible                                                                           Eligible                                            Is your                                                                                                                                                                   Not                                     
                                                                                                                                                    institution                                                                                                                                                               Eligible                                
                                                                                                                                                    among the most                                                                                                                                                                                                    
                                                                                                                                                    successful                                                                                                                                                                                                        
                                                                                                                                                    institutions?                                                                                                                                                                                                     
                                                                                                                                                    (See Table 3)                                                                                                                                                                                                     

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                     Yes                                                                                    No                                                                                        

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                    Not                                                                              Eligible                                                                                                         
                                                                                                                                                                    Eligible                                                                                                                                                                                          

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                                                                                                                                      

                                                                                                                                                                                                                                                                                                                                                                      
  --- -- --------------- -- --- -- -- -- -- -- -- -- ------------------ -- -- -- -- -- -- -- -- ---------- ---- -- -- -- -- -- -- -- -- -- -- -- -- --------------- ---------- -- -- ----- -- -- -- -- ---- -- -- -- -- -- -- -- -- -- ------------- ---------- -- -- ----- ---- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- ---------- ---- -- -- -- -- -- -- -- -- --

>  

## NRI Application Checklist 

Only electronic applications may be submitted to CSREES via Grants.gov
in response to this RFA. All applications submitted under the NRI must
contain the applicable elements outlined in these guidelines. The
following checklist has been prepared to assist in ensuring that the
application is complete prior to submission:

� Are you eligible to apply for the funding offered in this RFA?
Eligibility information is detailed in Part III, Eligibility
Information.

� Have all attachments been submitted in portable document format (PDF)?
CSREES will only accept PDF attachments. See Part III of the CSREES
Grants.gov Application Guide.

� Have you followed the guidelines for filling out your electronic
application provided in the CSREES Grants.gov Application Guide, which
is posted along with the electronic SF 424 R&R application package on
Grants.gov?

� Have you followed the guidelines for filling out your electronic
application provided in this RFA?

� Do all submitted PDF documents have one-inch margins and are typed or
word processed using no font size smaller than 12 point and six lines
per inch? Are all PDF documents numbered sequentially on each page of
the attachment? Are all page limitations for a given attachment
followed? Submitted proposals that do not meet these requirements for
PDF attachments are at risk for being returned without review.

� Have all components of the SF 424 Research and Related (R&R)
Application Package been completed? Did you use the "Check Package for
Errors" feature of the PureEdge viewer (see section 1.8 of the CSREES
Grants.gov Application Guide)?

-   SF 424 R&R Cover Sheet

-   R&R Other Project Information

-   R&R Senior/Key Person Profile

-   R&R Personal Data

-   R&R Budget

-   CSREES Supplemental Information Form

-   NRI Proposal Type Form

-   R&R Subaward Budget Attachment Form (if applicable)

� **[SF 424 R&R Cover Sheet]{.underline}**

-   Have all required fields been completed?

� **[R&R Other Project Information]{.underline}**

-   Has field 4, describing project potential or actual environmental
    impact, been properly completed?

-   [Project Summary/Abstract]{.underline}

> Did you use the suggested Project Summary/Abstract Template found at:
> <http://www.csrees.usda.gov/funding/templates/project_summary.doc>?
>
> Has the Project Summary PDF been attached to this form in Field 6?
>
> Are the names and affiliated organizations of all Project Directors
> listed at the top of the page in addition to the title of the project?
>
> Has a specific program priority been identified in the Project
> Summary?
>
> Does the Project Summary include research, education, and/or extension
> objectives, as appropriate?
>
> Does this section adhere to the format and page limitations?
>
> If the application is a resubmission, does it respond to previous
> review?

-   [Project Narrative]{.underline}

> Has the Project Narrative PDF been attached to this form in Field 7?
>
> Is the project fully described?
>
> If a renewal application, is a clearly marked progress report
> included?
>
> Does this section adhere to the format and page limitations?

-   [Response to Previous Review]{.underline} (for resubmissions and
    resubmitted applications)

> Has the Response to Previous Review been included in the Project
> Narrative?
>
> Are comments from the previous review addressed?
>
> Has the application been clearly and meaningfully revised and are the
> revisions briefly described?

-   [Bibliography & References Cited]{.underline}

> Has the Bibliography & References Cited PDF been attached to this form
> in Field 8?
>
> Are all references cited and are all citations referenced?
>
> Do all citations contain a title, the names of all authors, and are
> they in accepted journal format?

-   [Facilities & Other Resources]{.underline}

> Has the Facilities & Other Resources PDF been attached to this form in
> Field 9?
>
> Has a description of facilities, sufficient to indicate you will be
> able to carry out this project, been given?

-   [Equipment]{.underline}

> Has the Equipment PDF been attached to this form in Field 10?
>
> Is the description of your equipment sufficient to indicate that you
> will be able to carry out this project?

-   [Key Personnel & Management Plan]{.underline}

> Has the Key Personnel & Management Plan PDF been attached to this form
> in Field 11?
>
> Are roles and responsibilities of the PD, co-PD(s), and/or
> collaborator(s) clearly described?
>
> For integrated projects only, are the management plan and timeline for
> project implementation clearly described?

-   [Collaborative Arrangements]{.underline}

> Has the Collaborative Arrangements PDF been attached to this form in
> Field 11?

-   [Results from Prior NRI Support (if appropriate)]{.underline}

> Has the Results from Prior NRI Support PDF been attached to this form
> in Field 11?
>
> Does this section adhere to the format and page limitations?

-   [Appendices to Project Description]{.underline}

> Has the Appendices to Project Description PDF been attached to this
> form in Field 11?
>
> Are the reprints/preprints limited to 2 (as described in the
> instructions)?

� **[R&R Senior/Key Person Profile]{.underline}**

-   [Biographical Sketch]{.underline}

> Has the biographical sketch (vitae) PDF for the PD and each co-PD,
> senior associate, and other professional personnel been attached?

-   [Current and Pending Support]{.underline}

> Did you use the suggested Current and Pending Support Template found
> at:
> <http://www.csrees.usda.gov/funding/templates/current_pending.doc>?
>
> Has the Current and Pending Support PDF for personnel with PD or
> co-PD(s) been attached?
>
> Have all current and pending projects been listed and summarized,
> **including this proposal**?

� **[R&R Personal Data]{.underline}**

-   Have all fields been completed?

� **[R&R Budget]{.underline}**

-   ::: Definition-Term
    Have all fields been completed for each PD and co-PD(s)?
    :::

-   Are annual and summary budgets included? For multi-institution
    applications, has a subaward budget been included for each
    institution involved?

-   [Budget Justification]{.underline}

> Has the Budget Justification PDF been attached to this form in Field
> K?
>
> Are budget items individually justified?
>
> For multi-institutional applications, has a budget justification been
> included for each institution involved?
>
> Have any matching requirements been addressed, if applicable?

� **[Supplemental Information Form]{.underline}**

-   Has Field 1 been pre-populated such that "National Research
    Initiative Competitive Grants Program" appears for Funding
    Opportunity Name and "USDA-CSREES-NRI-001030" for Funding
    Opportunity Number?

-   Does Field 2 indicate the Program Code Name and Program Code to
    which you are applying?

-   [Conflict of Interest List]{.underline}

> Did you use the suggested Conflict of Interest Template found at:
> <http://www.csrees.usda.gov/funding/templates/conflict_of_interest.doc>?
>
> Has the Conflict of Interest List PDF been attached to this form in
> Field 8?
>
> Has a Conflict of Interest List been provided for all individuals who
> have submitted a Biographical Sketch?
>
> Does the Conflict of Interest list include the four categories as
> appropriate?

� **[NRI Proposal Type Form]{.underline}**

-   Is proposal type properly indicated on the NRI Proposal Type Form?

> []{#_C._Project_Types .anchor}

[^1]: Program soliciting only grants for integrated projects.

[^2]: Program soliciting grants for integrated and research projects.

[^3]: National Research Council 2001. *Grand Challenges in Environmental
    Sciences*. National Academy

    Press. 106 pp.

[^4]: Council for Agricultural Science and Technology. 2002. Invasive
    Pest Species: Impacts on Agricultural

    Production, Natural Resources, and the Environment. Louisiana State
    University, Baton Rouge. 18 pp.