*CURRICULUM VITAE*

PAT R. LEVITT

Business Address: Director

The John F. Kennedy Center for Research on Human Development

Vanderbilt University

Peabody Box 40, 230 Appleton Place

Nashville, TN 37203-5701

E-Mail: pat.levitt@vanderbilt.edu

Business Phone: 615-322-8242

Business Fax: 615-322-5910

**EDUCATION AND TRAINING**

1971-1975 University of Chicago B.A. Biological Sciences

Chicago, IL

1975-1978 University of California, San Diego Ph.D. Neurobiology

San Diego, CA

1979-1981 Yale University School of Medicine Postdoctoral Fellow

Section of Neuroanatomy

New Haven, CT

**APPOINTMENTS AND POSITIONS**

1981-82 Section of Neuroanatomy Assistant Professor

Yale University School of Medicine

New Haven, CT

1982-86 Department of Anatomy Assistant Professor

The Medical College of Pennsylvania

Philadelphia, PA

1986-89 Department of Anatomy Associate Professor

The Medical College of Pennsylvania

Philadelphia, PA

1989-93 Department of Anatomy & Neurobiology Professor

The Medical College of Pennsylvania

Philadelphia, PA

1991-93 Graduate School of Medical Sciences Associate Dean

The Medical School of Pennsylvania

Philadelphia, PA

**Appointments and Positions (cont.)**

1993-1996 Department of Neuroscience and Cell Biology Professor

UMDNJ

Robert Wood Johnson Medical School

Piscataway, NJ

1996- 2001 Department of Neurobiology Professor and Chairman

University of Pittsburgh School of Medicine

Pittsburgh, PA

1996-2001 Center for Neuroscience Co-Director

University of Pittsburgh

Pittsburgh, PA

1998-2002 Department of Neurobiology Thomas Detre Professor of

University of Pittsburgh Neuroscience

School of Medicine

Pittsburgh, PA

2002-present The John F. Kennedy Center for Research Director

on Human Development

Vanderbilt University

Nashville, TN

2002-present Department of Pharmacology Professor

Vanderbilt University School of Medicine

Nashville, TN

**HONORS AND AWARDS**

1978 Intrascience Foundation Graduate Student Research Award

1979-81 National Institutes of Health NINCDS Postdoctoral Fellowship

1981-83 March of Dimes Basil O-Connor Starter Research Grant

1981-84 NIH, NINCDS Research Grant

1982-85 Alfred P. Sloan Research Fellow

1983-85 National Down Syndrome Society Scholar Award

1985-89 Klingenstein Foundation Fellowship

1988-90 Scottish Rite Schizophrenia Research Foundation Award

1989-1999 NIH, NIMH Merit Award

1995-1997 NARSAD Windisch Established Investigator

1997, 2000 Grass Foundation Traveling Lecturer

2002 American Association for the Advancement of Science Research Fellow

2002-2005 McKnight Foundation Scholar

**PROFESSIONAL ORGANIZATIONS AND SCIENTIFIC SOCIETIES**

American Association for the Advancement of Science

American Society for Cell Biology

Society for Neuroscience

**EXTRAMURAL ACTIVITIES**

Co-Director, Cold Spring Harbor Neurobiology Summer Course,

Molecular Probes of the Nervous System*,* July-August 1987-1990

NIMH Task Force, Panel on Developmental Neurobiology, September 1993

Program Committee, International Society Developmental Neuroscience,
10th Biennial Meeting, July 1994

Program Committee, International Society Developmental Neuroscience,
11th Biennial Meeting, July1996

Program Committee, Society for Biological Psychiatry, 50th Annual
Meeting, May 1996

Program Committee, Society for Neuroscience, 1994-1997

Council, Society for Neuroscience, 1996-1997 (interim)

Member, Advisory Board, University of Arizona Program on Neural
Development, 1996-present

Task Force, American Jewish Healthcare Foundation, 1997-1999

Chairman, Program Committee, Society for Neuroscience, 1998

Council, Society for Neuroscience, 1998-2002

MacArthur Foundation Network, Brain Development and Development of
Behavior, 1998-present

Co-Organizer, Human Frontiers Science Program Symposium on Neural
Development, Riken, Japan, 1999

Member, Advisory Board, UCLA Center for the Study of Drugs of Abuse,
2000-present

Chair, NIMH Workshop on Developmental Neuroscience, Bethesda, MD, 2001

Member, Advisory Board, Cure Autism Now, 2001-present

National Panel to the Developing Child, 2003 - present

**Vanderbilt University School of Medicine**

2002-2003 Chair, Developmental Neurogenomics: Growing Connections from
the Genome to Behavior Conference

2002-present Member, Search Committee, Department of Psychiatry

2002-present Member, Executive Faculty Committee, School of Medicine

Member, Large Animal Faculty Advisory Committee

2002-present Member, MRB III Neuro Advisory Committee

2002-present Member, Neuroscience Council of the Vanderbilt Brain
Institute

2002-present Member, Research Enterprise Group

**Current Research Interests**

Development of circuitry in the vertebrate central nervous system

Molecular and developmental basis of neuropsychiatric disorders

Molecular specificity; role of genes and environment in cell fate and
assembly of functional systems

Prenatal exposure to drugs of abuse and effects on brain development

**EDITORIAL RESPONSIBILITIES**

1990-1997 Associate Editor, Journal of Neuroscience

1991-1998 Associate Editor, Perspectives on Developmental Neurobiology

1995-present Associate Editor, Biological Psychiatry

1996-present Associate Editor, Cerebral Cortex

1997-2001 Reviewing Editor, Journal of Neuroscience

1997-present Associate Editor, Neuron

2002-present Senior Editor, Journal of Neuroscience

## Ad Hoc Reviewer, Journals

Development; Developmental Biology; Experimental Neurology; European
Journal of Neuroscience; Journal of Comparative Neurology; Journal of
Neurobiology; Nature; Neuroscience; Science, Nature Neuroscience

**STUDY SECTIONS AND REVIEW BOARDS**

1984 Ad Hoc Member, NIH - Neurological Sciences Panel C2

1985 - 1988 Panel Member, NSF, Developmental Neurobiology

1990 - 1994 Regular Member, NIH, Neurological Sciences, Panel B1

1994 Ad Hoc Reviewer, NIMH, Laboratory of Neurophysiology

1994 - 1998 Member, NIH - National Review Reserve (NRR)

1996 - present March of Dimes Basil O'Connor Advisory Committee

1999 - present Board of Scientific Counselors, NIMH

2000 - present Scientific Advisory Board, Cure Autism Now

2002 - present Scientific Advisory Board, FDA National Center for
Toxicological Research

2003 - present Chair, Board of Scientific Counselors, NIMH

**GRANT AWARDS** (Only Grants as PI; titles denote active grants)

National Institutes of Health

NIMH R01 MH65299

June 2002 - May 2007

*Functional and Structural Adaptations in Forebrain Development*

National Institutes of Health

NIDA R01 DA11165

August 1996 - June 2006

*Brain Structure and Function after Fetal Cocaine Exposure*

McKnight Endowment Fund Neuroscience of Brain Disorders

June 2002 - 2005

*Molecular Strategies Towards Understanding Schizophrenia as a Disease
of the Synapse*

National Institutes of Health

NICHD P30 HD15052

July 2002 - July 2004

*John F. Kennedy Center for Mental Retardation*

National Institutes of Health

NIMH R01 MH45507-11

July 1989 - June 2004

*Factors Affecting Limbic System Assembly*

National Institutes of Health

NIMH Schizophrenia Center P50 MH45156

July 1998 - June 2003 (Project #2)

*Gene Expression Patterns in Prefrontal Cortical Circuitry*

National Institutes of Health

NIDA R01 DA13792-01

October 2000 - September 2003

*Fetal Cocaine and Gene Expression Defects in the Forebrain*

**Grant Awards (cont.)**

March of Dimes Basic Research Grant

July 2000 - June 2002

National Institutes of Health

NIMH Merit Award MH45507

September 1989 - June 1999

Human Frontiers Foundation

July 1996 - June 1999

March of Dimes

Basic Research Grant

July 1997 - May 1999

National Alliance for Research on Schizophrenia and Depression

NARSAD

May 1995 - April 1997

March of Dimes

Basic Research Grant

July 1994 - June 1996

National Institutes of Health

NIDA, Program Project Grant

April 1991 - June 1996 (PI, Project #2)

National Institutes of Health

NINDS

Program Project Grant

April 1986 - March 1995 (co-PI, Project #3)

National Institutes of Health

Minority Summer Research Apprenticeship Grant (Med. Coll. PA)

January 1993 - 1994

National Institutes of Health

NIA

September 1991 - August 1994

March of Dimes

Basic Research Grant

July 1983 - July 1990

National Institutes of Health-

NINCDS

December 1983 - April 1990

**Grant Awards (cont.)**

National Science Foundation

Basic Neuroscience Research Grant

March 1986 - February 1989

National Institutes of Health

NEI (Pilot Grant)

August 1985 - August 1986

**SEMINARS AND INVITED LECTURES**

**Invited Symposia and Workshops**

May 1981 1st International Tourettes Syndrome Symposium, New York

May 1983 Vieme Symposium International du Centre de recherche en
sciences neurologiques, University de Montreal, *Monoamine Innervation
of Cerebral Cortex*, Montreal

July 1983 International Society for Neurochemistry, Astrocyte Symposium,
Vancouver

January 1985 Winter Conference on Brain Research, University of Michigan

August 1985 International Society of Developmental Biology, *Cell
Interactions in Neural Development*,

Session Chairman, Los Angeles

October 1985 Neuroimmunology Social, Society for Neurosciences, Session
Organizer, Dallas

November 1985 *Neurobiology of Down Syndrome*, Session Chairman, New
York

January 1986 Winter Conference on Brain Research. Monoamine Oxidase
(MAO): *A Revisionist View of its Distribution and Function in the
Nervous System*, Workshop Chairman, Colorado

April 1986 Klingenstein Foundation Meeting of Neuroscience Fellows, New
York

May 1986 2nd Meeting in Neural Development (MIND), Columbia University,
New York

April 1988 Klingenstein Foundation Meeting of Neuroscience Fellows, New
York

November 1988 *Recovery of Function after Spinal Cord Injury*,
Pittsburgh, PA

October 1989 *From Early Embryogenesis to Neural Circuits: Cellular and
Molecular Strategies Applied to the Analysis of Vertebrate Brain
Development,* Society for Neuroscience, Co-Organizer, Phoenix

November 1991 Developmental Neurobiology Social, Society for
Neuroscience, New Orleans

February 1992 Hereditary Disease Foundation*, Transplantation as a Tool
for Understanding the Neurobiology of Huntington\'s Disease,* Los
Angeles

May 1992 Northeast Developmental Biology Meeting, *Cell-cell
Interactions and Signaling in Development*, Session Chairman and
Speaker, Woods Hole, MA

June 1993 NATO Meeting, *Neuronal Specificity: Maps & Molecules*,
Cargese, Corsica

July 1993 James S. McDonnell Summer Institute & Conference, *Neural &
Psychological Development*, Squaw Creek, Lake Tahoe, CA

November 1993 Society for Neuroscience 19th Annual Meeting, *Brain
Microglia in Development, Injury and Aging*, Washington, DC

July 1994 Gordon Conference, *Neuronal Development,* Newport, RI

July 1994 International Society Developmental Biology 10th Biennial
Meeting, San Diego, CA

November 1994 Ciba Foundation, *Development of the Cerebral Cortex*,
London

September 1995 Second Corsica International Workshop, *Generation of
Phenotypic Diversity in the Cortex*, Corsica

December 1995 ACNP, *Cell Recognition Molecules in Brain Development and
Psychiatric Disorders,* San Juan, PR

January 1996 Winter Conference on Brain Research, *Neural Recognition
Molecules in Development, Regeneration and Neuropsychiatric Disorders*,
Vale, CO

February 1996 21st Annual Seiriken Conference, *Development and
Differentiation of the Nervous System*,

Okazaki, Japan

March 1996 Association pour la Neuro-Psycho-Pharmacologie,
*Neurogenesis: From Egg to Brain*, Paris, France

**Invited Symposia and Workshops (cont.)**

May 1996 Society for Biological Psychiatry, 50th Anniversary Meeting,
*Neurodevelopment and Psychiatric Disorders*, New York

December 1996 Association for Research in Nervous and Mental Disease,
*Basics of Cortical Development,*

New York

December 1996 ACNP, *Thalamus and Schizophrenia*, San Juan, Puerto Rico

May 1997 New York Academy of Sciences, *Neural-immune interactions: the
role of cytokines in the nervous system, Opiates, Cytokines an
Neuroimmune Interactions Following Injury in the Developing Brain, New
York*

July 1997 National Institutes for Mental Health, Workshop,
*Developmental Etiology of Schizophrenia*, Washington, DC

September 1997 MacArthur Foundation Network Workshop III, *Neuronal
Development and Development of Behavior*, Chicago, IL

September 1997 New York Academy of Sciences Symposium, *Prenatal Cocaine
Exposure and Brain Development - Molecular and Structural Changes in
Cortical Development Following Prenatal Cocaine Exposure,* Washington,
DC

November 1997 MacArthur Foundation Network Workshop V, *Neuronal
Development and Development of Behavior,* Boston, MA

June 1998 McDonnell-Pew Summer Institute, N*euronal Development,* Lake
Tahoe, CA

March 1999 Human Frontiers Science Program Symposium on Neural
Development, *Progenitor Cell Regulation of Cortical Development,*
Riken, Japan

April, 1999 Novartis Foundation Meeting on Cortical Development and
Evolution: *Not All Progenitors are Created Equal: Role in Cortical
Development*, London

October 1999 Kärger Workshop, *Molecular Regulation of Regional
Specification in the Cortex,* Miami, FL.

October 1999 J.B. Johnson Club, *Role of Conserved Cell Adhesion
Molecules in Axon Guidance,* Miami FL.

April 2000 Modularity in Development, Delmenhorst Conference,
*Mechanisms of Cortical Patterning*, Delmenhorst, Germany

October 2000 Juan March Conference on Mechanisms of Cell Proliferation,
Migration and Assembly, Role of HGF/Scatter Factor in Forebrain
Development, Madrid, Spain

June 2001 24^th^ Annual Meeting of the Canadian College
Neuropsychopharmacology (CCNP), Banff, Alberta

July 2001 Gordon Conference on Catecholamines, *Prenatal Cocaine
Exposure and Adaptive Developmental Mechanisms*, Shrewsbury, NH

July 2001 NIMH Workshop of Brain Development and Behavior, Bethesda, MD

October 2001 National Association for Regulatory Administration, *The
Myths and Facts of Brain-Based Education*,

Pittsburgh, PA

January 2002 NIMH, NINDS Workshop: *Setting Priorities for Molecular
Neuroanatomy in the Postgenomic Era*, Laguna Beach, CA

April 2002 Cure Autism Now workshop: *Neurobiology of Autism*, Santa
Monica, CA

May 2002 Mead-Johnson LCPUFA, *Development of Primate Brain*,
Washington, DC

June 2002 4^th^ Neurogenomics Conference, Bar Harbor, ME

July 2002 International Narcotics Research Conference, Asilomar, CA

February 2003 Juan March Meeting: Synaptic Dysfunction and
Schizophrenia, Madrid Spain (Co-Organizer)

July 2003 IBRO: Development and Evolution of the Cerebral Cortex,
Prague, Czech Republic

**Community Outreach Invited Lectures**

September 1996 American Health Foundation, *Is there a Critical Period
in Brain Development*, Washington, DC

October 1996 Institute for Alternative Futures, Congressional Seminar,
*Current Advances in Neuroscience*, Washington, DC

May 1997 Nurturing Neurons, *Neurobiology of Prenatal and Postnatal
Development*, Pittsburgh, PA

November 1997 Leadership Pittsburgh XIV: *Preparing Our Kids: Models for
Learning. Brain Development and Development of Learning,* Pittsburgh, PA

October 1998 Allegheny County Intermediate Unit, Superintendents
Retreat. *Brain Development and Developing of Learning,* Dawson, PA

April 1999 American Education Research Association, *Brain Science and
Education: Current Thinking in Neuroscience - What Educators Should
Know,* Montreal, Canada

February 2000 Quaker Valley School District In-Service Keynote Address,
*Myths of Neuroscience-Based Education,* North Hills, PA

March 2000 Brain Awareness Week Public Lecture, Pittsburgh Neuroscience
Society, *Effects of Drug Abuse on Brain Formation and Function,*
Pittsburgh, PA

March 2000 Academy of Educational Leadership, Superintendents and
Administrators of Albuquerque Public Schools, *The Myths and Facts of
Brain-Based Education,* Albuquerque, NM

March 2000 Academy of Educational Leadership, Faculty, Albuquerque
Public Schools, *Are There Applications of Neuroscience-Based Research
in the Classroom,* Albuquerque, NM

October 2001 NIMH Workshop on Developmental Neuroscience, Chair,
Bethesda, MD

March 2002 Western PA Business and Legislative Leadership Meeting, The
Myths and Facts of

Brain-Based Education, Pittsburgh, PA

March 2003 Exchange Club of Nashville, Kennedy Center Update, Nashville,
TN

April 2003 Richmond Children's Museum, Neuroscience in our Neighborhood,
Richmond, VA

April 2003 Middle Tennessee Autism Society, Kennedy Center Update,
Nashville, TN

**Invited Seminars**

January 1981 University of Vermont School of Medicine, Department of
Anatomy and Neurobiology

November 1981 Stanford University School of Medicine, Department of
Neurobiology

January 1982 Cornell university College of Medicine, Department of Cell
Biology

April 1982 New York University School of Medicine, Department of
Pharmacology

January 1984 Jefferson University School of Medicine, Department of
Anatomy

March 1984 National Institutes of Health, Heart, Lung and Blood
Institute

December 1984 University of Virginia School of Medicine, Department of
Anatomy

January 1985 Temple University, Department of Biology

May 1985 University of Rochester, Department of Anatomy, SUNY, Upstate
Medical Center

Departments of Physiology and Biochemistry

June 1985 Hershey Medical Center, Departments of Pharmacology and
Genetics

August 1985 Stanford University School of Medicine, Department of
Neurobiology

> Mt. Sinai School of Medicine, Department of Psychiatry

September 1985 Boston University School of Medicine, Department of
Anatomy

November 1985 Columbia University College of Physicians and Surgeons,
Department of Anatomy and Cell Biology

May 1986 New York University, Department of Biology

August 1986 Cold Spring Harbor, Immunoglobulins and The Nervous System
Course

November 1986 Rutgers University, Robert W. Johnson Medical School,
Department of Anatomy

March 1987 E.K. Shriver Center, Department of Biochemistry, Waltham, MA

October 1987 University of Heidelberg, Department of Neurobiology

October 1987 University of Zurich, Pharmacology Institute

**Invited Seminars (cont.)**

February 1988 University of Pittsburgh School of Medicine, Department of
Anatomy and Cell Biology

March 1988 E.I. Dupont du Moirs Co., Division of Neurobiology

June 1988 University of Toronto School of Medicine, Department of
Anatomy

July 1988 New Jersey School of Osteopathic Medicine, Department of
Anatomy

September 1988 Case Western Reserve University School of Medicine,
Neuroscience Program

December 1988 Georgetown University School of Medicine, Department of
Anatomy & Cell Biology

January 1989 National Institutes of Health, Animal Research Center

April 1989 Florida State University, Psychobiology Program

May 1989 John Hopkins University School of Medicine, Department of
Neuroscience

January 1990 Columbia University College of Physicians and Surgeons,
Center for Reproductive Biology

February 1990 Genentech, Inc., Department of Developmental Biology

February 1990 University of California, San Francisco School of
Medicine, Program in Neuroscience

February 1990 University of California, Berkeley, Department of
Biochemistry

February 1990 Stanford University School of Medicine, Department of
Neurobiology

March 1990 University of Washington School of Medicine, Program in
Neuroscience

April 1990 University of Connecticut, Storrs, Department of Neurobiology
and Physiology

March 1991 SUNY, Buffalo, Program in Neurosciences

November 1991 University of Massachusetts, Neuroscience Program

November 1991 UCLA, Department of Psychiatry and Neuroscience Program

November 1991 UC, Irvine, Department of Anatomy & Neurobiology

November 1991 Genentech, Department of Neuroscience

March 1992 Cornell Medical College, Department of Neurology & Program in
Neuroscience

March 1992 University of Tennessee, Memphis, Department of Anatomy &
Neurobiology

September 1992 UMDNJ, Robert Wood Johnson Medical School, Center for
Neuroscience

October 1992 Albert Einstein School of Medicine, Kennedy Center for
Mental Retardation

November 1992 Bowman Gray School of Medicine, Wake Forrest University,
Department of Anatomy

January 1993 Albert Einstein School of Medicine, Department of Pathology

February 1993 University of California, Berkeley, Department of Cell &
Molecular Biology

February 1993 Barrow Neurological Institute of Phoenix

March 1993 University of North Carolina, Department of Anatomy & Cell
Biology

April 1993 University of Pittsburgh, Department of Behavioral
Neuroscience

May 1993 Hahneman University, Department of Physiology

October 1993 Rockefeller University, SUNY, Stonybrook, Department of
Neurobiology & Behavior

January 1994 NYU Medical Center, Department of Pharmacology

February, 1994 Mt. Sinai School of Medicine, Center for Neurobiology

March, 1994 Yale University School of Medicine, Section of Neurobiology

April 1994 University of Texas, Southwest Medical Center, Program in
Cell Biology

October 1994 University of Virginia, Program in Neuroscience, Princeton
University, Department of Biology

November 1994 University of Pennsylvania, Neuroscience Program

January 1995 National Institutes of Health, NIMH, Clinical Brain
Disorders Branch

March 1995 Cedar Crest College, Program in Genetic Engineering,
University of Chicago, Program in Neurobiology

January 1996 SUNY, Syracuse, Program in Neuroscience

March 1996 INSERM Unite 371, Program in Developmental Neurobiology,
Lyon, France

November 1996 University of Pittsburgh, Program in Pathology

January 1997 Emory University, Program in Neuroscience

May 1997 Hershey Medical School, Program in Neuroscience

October 1997 Case Western Reserve University, Department of Neuroscience

November 1997 Carnegie Mellon University, Department of Biological
Sciences

**Invited Seminars (cont.)**

December 1997 University of Pittsburgh School of Medicine, Department of
Neurology

January 1998 University of Pittsburgh, Department of Neuroscience

March 1998 University of Florida, Program in Neuroscience

May 1998 Chatham College, Seminars in Biology Program

July 1998 Campus Biomedicus, Department of Neuroscience, Rome, Italy

January 1999 University of California-Davis, Program in Neuroscience

March 1999 Cornell Medical College, Program in Neurobiology

March 1999 CUNY, Program in Biology

May 1999 Brown University, Department of Neuroscience

May 1999 Brown University, Department of Neurology Grand Rounds

July 1999 Max Planck Institute, Tubingen, Germany

March 2000 Oregon Regional Primate Center, Beaverton, OR

May 2000 Pasteur Institute, Neuroscience Program, Paris France

June 2000 Philadelphia Chapter, Society for Neuroscience, Grass Lecture

November 2000 Cleveland Clinic Foundation, Department of Neurosciences,
Lerner Research Inst Clinic

January 2001 Weizman Institute of Science, Rehovot, Israel

January 2001 The John F. Kennedy Center for Research on Human
Development, Vanderbilt University

January 2001 Center for Biotechnology and Medicine, Rutgers University

January 2001 Roche Biosciences, Palo Alto, CA

May 2001 Arkansas Chapter, Society for Neuroscience Grass Foundation
Lecture, University of Arkansas for Medical Sciences

May 2001 Arkansas Chapter, Society for Neuroscience Grass Foundation
Lecture, National Center for Toxicology Research

May 2001 The University of Tennessee-Memphis, Center for Neuroscience

May 2001 Wake Forest University School of Medicine, Neuroscience Program

October 2001 University of Maryland School of Medicine, Program in
Neuroscience

November 2001 UCLA, Neuropsychiatric Institute

March 2002 Vanderbilt University, Department of Pharmacology

May 2002 Boston University School of Medicine, Integrated Neuroscience
Program

October 2002 Wayne State University, Program in Neuroscience

January 2003 Stanford University School of Medicine, Stanford Brain
Research Institute

May 2003 UCLA, Department of Molecular Pharmacology

**PROFESSIONAL ACTIVITIES: Teaching**

**University of California, San Diego**

1976-1978 Basic Neuroscience (Laboratory)

**Yale University of Medicine**

1979-1982 Basic Neuroscience (Lectures and Lab)

> Graduate Course, Nerves, Genes and Behavior

**The Medical College of Pennsylvania**

1983-1993 Medical Histology & Cell Biology (Lectures and Lab)

1985-1993 Graduate Course Director, Advanced Topics in Neurobiology

1987-1993 Graduate Course Director, Developmental Neurobiology

1991-1993 Graduate Course Co-Director:, Cell & Molecular Biology

1991-1993 Basic Medical Neuroscience (Lectures and Lab)

**Teaching (con't)**

**Robert Wood Johnson Medical School and Rutgers University**

1994-1996 Graduate Course Co-Director, Developmental Neurobiology

1994-1996 Basic Medical Neuroscience

Graduate Course, Advanced Cell Biology

**University of Pittsburgh School of Medicine**

1997-2002 Graduate Course Co-Director, Neurobiology Journal Club

Graduate Course Co-Director, Developmental Neurobiology

Graduate Course, Neuroscience IV: Diseases

Graduate Course Director, Neuroscience III: Systems

Neuroscience MSII

**Vanderbilt University**

2003 Graduate Course, Advanced Molecular Neuroscience

Graduate Course, Introduction to Fundamental Neuroscience

**Woods Hole Marine Biology Laboratory**

2003 Neurobiology -- lectures in molecular neurobiology section of
course

**PUBLICATIONS**

1\. Levitt, P., Moore, R.Y. and Garber, B.B. Selective cell association
on catecholamine neurons in brain aggregates in vitro. *Brain Research*
111: 311-320, 1976.

2\. Levitt, P. and Moore, R.Y. Noradrenaline neuron innervation of the
neocortex in the rat. *Brain Research* 139: 219-231, 1978.

3\. Levitt, P. and Moore, R.Y. Developmental organization of raphe
serotonin neuron groups in the rat. *Anat. and Embryol.* 154: 241-251,
1978.

4\. Levitt, P. and Moore, R.Y. Development of the noradrenergic
innervation of the neocortex. *Brain Research* 162: 243-259, 1979.

5\. Levitt, P. and Moore, R.Y. Origin and organization of brainstem
catecholamine innervation in the rat. *J. Comp. Neuro.* 186: 505-528,
1979.

6\. Miller, A.L., Levitt, P., Ingram, H. and Lewis, L. Properties of
acid β-D galactosidase isolated from I-cell disease brain. *J.
Neurochem.* 32: 1479-1485, 1979.

7\. Levitt, P. and Moore, R.Y. Organization of brainstem noradrenaline
hyperinnervation following neonatal 6-hydroxydopamine treatment in rat.
*Anat. and Embryol.* 158: 133-150, 1980.

8\. Levitt, P. and Rakic, P. Immunoperoxidase localization of glial
fibrillary acidic protein in radial glial cells and astrocytes of the
developing Rhesus monkey brain. *J. Comp. Neuro.* 193: 817-848, 1980.

**Publications (cont.)**

9\. Levitt, P., Cooper, M.L. and Rakic, P. Coexistence of neuronal and
glial precursor cells in the ventricular zone of the fetal monkey
cerebrum: An ultrastructural immunoperoxidase analysis. *J. Neurosci.*
1: 27-39, 1981.

10\. Levitt, P. and Noebels, J. Mutant mouse tottering (tg): Selective
increase of locus coeruleus axons in a defined single locus mutation.
*Proc. Nat. Acad. Sci.* 78: 4630-4634, 1981.

11**.** Levitt, P. and Rakic, P. The time of genesis, embryonic origin
and differentiation of the brain stem monoamines neurons in the Rhesus
monkey. *Develop. Brain Res.* 4:35-57, 1982.

12\. Levitt, P. and Pintar, J.E., Breakfield, X.O. Immunocytochemical
demonstration of monoamine oxidase B in brain astrocytes and
serotonergic neurons. *Proc. Natl. Acad. Sci.* 79: 6385-6389, 1982.

13\. Pintar, J.E., Levitt, P., Salach, J.L., Weyler, W., Rosenberg, M.B.
and Breakefield, X.O. Specificity of antisera prepared against pure
bovine MAO-B. *Brain Research* 176: 127-139, 1983.

14\. Levitt, P., Cooper, M.L. and Rakic, P. Early divergence and
changing proportions of neuronal and glial precursor cells in the
primate cerebral ventricular zone. *Dev. Biol.* 96: 472-484, 1983.

15\. DeCamilli, P., Miller, P.E., Levitt, P., Walter, V. and Greengood,
P. Anatomy of cerebellar Purkinje cells in the rat determined by a
specific immunohistochemical marker. *Neuroscience* 11: 761-817, 1984.

16\. Levitt, P. A monoclonal antibody to limbic system neurons.
*Science* 223: 299-301, 1984.

17\. Levitt, P., Rakic, P., DeCamilli, P. and Greengood, P. Emergence of
cyclic Guanosine 3\':5\"-Monophosphate-dependent protein kinase
immunoreactivity developing rhesus monkey cerebellum: Correlative
immunocytochemical and electron microscopic analysis. *J. Neurosci*. 4:
2553-2564, 1984.

18\. Levitt, P., Rakic, P. and Goldman-Rakic, P. Region-specific
distribution of catecholamine afferents in primate cerebral cortex: A
fluorescence histochemical study. *J. Comp. Neuro.* 227: 23-36, 1984.

19\. Shaywitz, B.A., Teicher, M.H., Cohen, D.J., Anderson, G.M., Young,
J.G. and Levitt, P. Dopaminergic but not noradrenergic mediation of
hyperactivity and performance deficits in the developing rat pup.
*Psychopharm.* 82: 73-77, 1984.

20\. Levitt, P., Maxwell, G.D. and Pintar, J.E. Specific cellular
expression of monoamine oxidase-B during early stages of quail
embryogenesis. *Dev. Biol*. 110: 346-361, 1985.

21\. Levitt, P. Relating molecular specificity to normal and abnormal
brain development. *Ann. N.Y. Acad. Sci.* 450: 239-246, 1985.

22\. Levine, R.J.C., Kensler, R.W. and Levitt, P. Crossbridge and
backbone structure of invertebrate thick filaments. *Biophys. J.* 49:
135-136, 1985.

23\. Levitt, D., Bard, J., Daner, R. and Levitt, P. Selective infection
of astrocytes by *Chlamydia trachomatis* in primary mixed neuron-glial
cultures. *Infection and Immunity* 54: 913-916, 1986.

24\. Levitt, P., Lau, C., Pylypiw, A. and Ross, L.L. Central adrenergic
receptor changes in the inherited noradrenergic hyperinnervated mutant
mouse tottering. *Brain Research* 418: 174-177, 1987.

**Publications (cont.)**

25\. Levitt, P. Normal pharmacological and morphometric parameters in
the noradrenergic hyperinnervated mutant mouse, \"tottering.\" *Cell and
Tissue Res.* 252: 175-180, 1988.

26\. Horton, H.L. and Levitt, P. A unique membrane protein is expressed
on early developing limbic system axons and cortical targets. *J.
Neurosci.* 8: 4653-4661, 1988.

27\. Keller, F. and Levitt, P. Developmental and regeneration-associated
regulation of the limbic system-associated membrane protein in explant
cultures of the rat brain*. Neuroscience* 28: 455-474, 1989.

28\. Keller, F., Rimvall, K., Barbe, M.F. and Levitt, P. A membrane
glycoprotein associated with the limbic system mediates the formation of
the septo-hippocampal pathway in vitro. *Neuron* 3: 551-661, 1989.

29\. Zacco, A., Cooper, V., Hyland-Fisher, S., Chantler, P.D., Horton,
H.L. and Levitt, P. Isolation, biochemical characterization and
ultrastructural analysis of the limbic system-associated membrane
protein (LAMP), a protein expressed on neurons comprising functional
neural circuits. *J. Neurosci.* 10: 73-90, 1990.

30\. Murray, M., Wang, S.D., Goldberger, M.E. and Levitt, P.
Modification of astrocytes in the spinal cord following dorsal root or
peripheral nerve lesions. *Exp. Neurol.* 110: 248-257, 1990.

31\. Pennypacker, K.P., Fischer, I. and Levitt, P**.** Early *in vitro*
genesis and differentiation of axons and dendrites by hippocampal
neurons analyzed quantitatively with neurofilament-H and
microtubule-associated protein 2 antibodies. *Exp. Neurol.* 111: 25-35,
1991.

32\. Chesselet, M.-F., Gonzalez, C. and Levitt, P. Heterogeneous
distribution of the limbic system-associated membrane protein (LAMP) in
the caudate nucleus and substantia nigra of the cat. *Neurosci*. 40:
725-733, 1991.

33\. Barbe, M.F. and Levitt, P. The early commitment of fetal neurons to
limbic cortex. *J. Neurosci.* 11: 519-533, 1991.

34\. Rinaman, L., Milligan, C.E. and Levitt, P. Persistence of
fluoro-gold following degeneration of labeled motoneurons is due to
phagocytosis by microglia and macrophages. *Neuroscience* 44: 765-776,
1991.

35\. Rinaman, L. and Levitt, P. Access to gastric tissue promotes the
survival of axotomized neurons in the dorsal motor nucleus of the vagus
in neonatal rats**.** *J. Comp. Neurol.* 313: 213-226, 1991.

36\. Milligan, C.E., Cunningham, T.J. and Levitt, P. Differential
immunochemical markers reveal the normal distribution of brain
macrophages and microglia in the developing rat brain. *J. Comp.
Neurol.* 314: 125-135, 1991.

37\. Milligan, C.E**.,** Levitt, P. and Cunningham, T.J. Brain
macrophages and microglia respond differently to lesions of the
developing and adult visual system. *J. Comp. Neurol*. 314: 136-146,
1991.

38\. Miller, M., Bower, E., Levitt, P., Li, D. and Chantler, P.D. Myosin
II distribution is consistent with a role in growth cone motility but
not synaptic vesicle mobilization. *Neuron* 8: 25-44, 1992.

39\. Qian, J., Bull, M.S. and Levitt, P. Target-derived astroglia
regulate axonal growth in a region-specific manner. *Dev.* *Biol.* 149:
278-294, 1992.

40\. Barbe, M.F. and Levitt, P. Attraction of specific thalamic input by
cerebral grafts depends on the molecular identity of the implant. *Proc.
Natl. Acad. Sci*. 89: 3706-3710, 1992.

**Publications (cont.)**

41\. Levitt, P., Barbe, M.F. and Ferri, R.T. Transplants of limbic and
neocortex reveal mechanisms of generating phenotypic diversity in the
cerebral cortex. *J. Neur. Transpl. Plasticity* 3: 175, 1992.

42\. Battisti, W., Shinar, Levitt, P. and Murray, M. Temporal and
spatial patterns of expression of laminin, chondroitin sulfate
proteoglycan and HNK-1 immunoreactivity during regeneration in the
goldfish optic nerve. *J. Neurocytol*. 21: 557- 573, 1992.

43\. Silver, J., Edwards, M.A. and Levitt, P. Immunocytochemical
demonstration of early appearing astroglial structures that form
boundaries and pathways along axon tracts in the fetal brain. *J. Comp.
Neurol*. 328: 415-436, 1993.

44\. Ferri, R.T. and Levitt, P. Cerebral cortical progenitors are fated
to produce region-specific neuronal populations. *Cerebral Cortex* 3:
187-198, 1993.

45\. Levitt, P., Ferri, R.T. and Barbe, M.F. Progressive acquisition of
cortical phenotypes as a mechanism for specifying the developing
cerebral cortex. *Perspectives Dev. Neurobiol.* 1: 65-74, 1993.

46\. Rinaman, L. and Levitt, P. Establishment of vagal sensorimotor
circuits during fetal development in rats. *J. Neurobiol.* 24: 641-659,
1993.

47\. Prouty, S. and Levitt, P. Immunocytochemical analysis of a novel
carbohydrate differential antigen (CDA-3C2) associated with olfactory
and otic systems during embryogenesis in the rat. *J. Comp. Neurol.*
332: 444-470, 1993.

48\. Prouty, S. and Levitt, P. Immunoelectron microscopic analysis of a
novel carbohydrate differentiation antigen (CDA-3C2) in the developing
rat olfactory and otic systems. *J. Comp. Neurol*. 332: 471-486, 1993.

49\. Goldberger, M.E., Coleman, E., Croul, S. and Levitt, P. Partial
deafferentation of cat spinal neurons results in permanent changes in
cell surface molecular expression and metabolic activity. *Exp. Neurol.*
123: 74-80, 1993.

50\. Eberle-Wang, K., Levitt, P. and Simansky, K.J. Abdominal Vagotomy
dissociates the anorectic mechanisms for peripheral serotonin and
cholecystokinin. *Amer. J. Physiol.* 265: 602-608, 1993.

51\. Qian, J., Wang, H.-Y., Fisher, I., Friedman, E. and Levitt, P.
Involvement of protein kinase C in axonal growth-promoting effect on
spinal cord neurons by target-derived astrocytes. *J. Neurobiol.* 25:
1593-1612, 1994.

52\. Barbe, M.F. and Levitt, P. Age-dependent specification of the
cortico cortical connections of cerebral grafts.

*J**.*** *Neurosci.* 15: 1819-1834, 1995.

53\. Ferri, R.T. and Levitt, P. Regulation of regional differences in
the differentiation of cerebral cortical neurons by EGF family-matrix
interactions. *Development* 121: 1151-1160, 1995.

54\. Zhukareva, V. and Levitt, P. The limbic system-associated membrane
protein (LAMP) selectively mediates interactions with specific central
neuron populations. *Development* 121: 1161-1172, 1995.

55\. Milligan, C.E., Webster, L., Piros, E.T., Evans, C., Cunningham,
T.J. and Levitt, P. Induction of opioid receptor-mediated macrophage
chemotactic activity after neonatal brain injury. *J. Immunol.* 154:
6571-6581, 1995.

56\. Pimenta, A., Zhukareva, V., Barbe, M.F., Reinoso, B., Grimley, C.,
Henzel, W., Fischer, I. and Levitt, P. The limbic system-associated
membrane protein is an ig superfamily member that mediates selective
neuronal growth and axon targeting. *Neuron* 15: 287-297, 1995.

**Publications (cont.)**

57\. Cote, P.-Y., Sadikot, A.F., Levitt, P. and Parent, A. Distribution
of the limbic system-associated membrane protein immunoreactivity in
primate basal ganglia. *Neuroscience* 69: 71-81: 1995.

58\. Wang, X.-H., Levitt, P., Grayson, D.R. and Murphy, E.H.
Intrauterine cocaine exposure of rabbits: persistent elevation of
GABA-immunoreactive neurons in anterior cingulate cortex but not visual
cortex. *Brain Res.* 689: 32-46, 1995.

59\. Reinoso, B.S., Undie, A.S. and Levitt, P. Dopamine receptors
mediate differential morphological effects on cerebral cortical neurons
in vitro. *J. Neurosci. Res.* 43: 439-453, 1996.

60\. Jones, L., Fischer, I. and Levitt, P. Nonuniform alteration of
dendritic development in the cerebral cortex following prenatal cocaine
exposure. *Cereb. Cortex* 6: 431-445, 1996.

61\. Eagleson, K.L., Ferri, R.T. and Levitt, P. Complementary
distribution of collagen type IV and the epidermal growth factor
receptor in the embryonic telencephalon. *Cereb. Cortex* 6: 540-549,
1996

62\. Pimenta, A., Fischer, I. and Levitt, P. cDNA cloning and structural
analysis of the human limbic-system-associated membrane protein (LAMP).
*Gene* 170: 189-195, 1996.

63\. Wang, X.-W., Levitt, P., O\'Brien Jenkins, A. and Murphy, E.H.
Normal development of tyrosine hydroxylase and serotonin immunoreactive
fibers innervating anterior cingulate cortex and visual cortex in
rabbits exposed prenatally to cocaine. *Dev. Brain Res*. 715: 221-224,
1996.

64\. Ferri, R.T., Eagleson, K. and Levitt, P. Environmental signals
influence expression of a cortical areal phenotype *in vitro*
independent of effects on progenitor cell proliferation. *Dev. Biol.*
175: 184-190, 1996.

65\. Mermelstein, F., Yeung, K., Cao, J., Inostroza, J.A.,
Erdjument-Bromage, H., Eagleson, K., Landsman, D., Levitt, P., Tempst,
P. and Reinberg, D. Requirement of corepressor for Dr1-mediated
repression of transcription. *Genes and Dev.* 10: 1033-1048, 1996.

66\. Cote, P-.Y., Levitt, P. and Parent, A. Distribution of the limbic
system-associated membrane protein (LAMP) immunoreactivity in primate
amygdala complex and hippocampus. *Hippocampus* 6: 483-494, 1996.

67\. Reinoso, B.S., Pimenta, A.F. and Levitt, P. Expression of the mRNAs
encoding the limbic system-associated membrane protein (LAMP): I. Adult
rat brain. *J. Comp. Neurol*. 375: 274-288, 1996.

68\. Pimenta, A.F., Reinoso, B.S. and Levitt, P. Expression of the mRNAs
encoding the limbic system-associated membrane protein (LAMP) II. Fetal
rat brain. *J. Comp. Neurol.* 375: 289-302, 1996.

69\. Nicholson-Flynn, K., Hitchcock-DeGregori, S.E. and Levitt, P.
Restricted expression of the actin-regulatory protein, tropomyosin,
defines distinct boundaries, evaginating neuropithelium, and choroid
plexus forerunners during early CNS development. *J. Neurosci.* 16:
6853-6863, 1996.

70\. Hoffman, J.R., Boyne, L.J., Levitt, P. and Fischer, I. Short
exposure to methylazoxymethanol causes a long-term inhibition of axonal
outgrowth from cultured embryonic rat hippocampal neurons. *J. Neurosci.
Res.* 46: 349-359-1996.

71\. Smigrodzki, R. and Levitt, P. The α 1 subunit of soluble guanylyl
cyclase is expressed prenatally in the rat brain. *Dev. Brain Res.* 97:
226-234, 1997.

**Publications (cont.)**

72\. Levitt, P., Eagleson, K.L., Chan, A.V., Ferri, R.T. and Lillien, L.
Signaling pathways that regulate specification of neurons in developing
cerebral cortex. *Dev. Neurosci.* 19: 6-8, 1997.

73\. Eagleson, K.L., Lillien, L., Chan, A.V. and Levitt, P. Mechanisms
specifying area fate in cortex include cell-cycle-dependent decisions
and the capacity of progenitors to express phenotype memory.
*Development* 124: 1623-1630, 1997.

74\. Levitt, P., Harvey, John A., Friedman, E. and Murphy E. H. New
evidence for neurotransmitter influences on brain development. *TINS*
20: 269-274-1997.

75\. Burrows, R.C., Wancio, D., Levitt, P. and Lillien, L. Response
diversity and the timing of progenitor cell maturation are regulated by
developmental changes in EGF-R expression in the cortex. *Neuron* 19:
251-267, 1997.

76\. Murphy, Hazel, E., Itzhak, F., Friedman, E., Grayson, D., Jones,
L., Levitt, P., O\'Brien-Jenkins, A., Wang, H.-Y. and Wang, X.-H.
Cocaine administration in pregnant rabbits alters cortical structure and
function in their progeny in the absence of maternal seizures. *Exp.
Brain Res.* 114: 433-441, 1997.

77\. Zukareva, V., Chernevskaya, N., Pimenta, A., Nowycky, M. and
Levitt, P. Limbic system-associated membrane protein (LAMP) induces
neurite outgrowth and intracellular Ca2+ increase in primary fetal
neurons. *Molec. and Cell. Neurosci.* 10: 43-55, 1997.

78\. Zhang, J.-H., Pimenta, A.F., Levitt, P., Zhou, R. Dynamic
expression suggests multiple roles of the eph family receptor
brain-specific kinase (Bsk) during mouse neurogenesis. *Molec. Brain
Res.* 47: 202-214, 1997.

79\. Zhang, B., Levitt, P. and Murray, M. Induction of presynaptic
re-expression of an adhesion protein in lamina II after dorsal root
deafferentation in adult rat spinal cord. *Exp. Neurol*. 149: 468-472,
1998.

80\. Gao, P.-P., Yue, Y., Zhang, J.-H., Cerretti, D.P., Levitt, P. and
Zhou, R. Regulation of thalamic neurite outgrowth by the Eph ligand
ephrin-A-5: Implications in the development of thalamocortical
projections. *Proc. Nat. Acad. Sci.* 95: 5329-5334, 1998.

81\. Card, J.P., Levitt, P. and Enquist, L.W. Different patterns of
neuronal injection after intracerebral injections of two strains of
pseudorabies virus*. J. Virol.* 72: 4434-4441, 1998.

82\. Pimenta, A.F., Tsui, L.-C., Heng, H.H.Q. and Levitt, P. Assignment
of the gene encoding the limbic system-associated membrane protein
(LAMP) to mouse chromosome 16B5 and human Chromosome 3 q13.2-q21.
*Genomics* 49: 472-474, 1998.

83\. Cunningham, T.J., Hodge, L., Speicher, D., Reim, D., Tyler‑Polsz,
C., Levitt, P., Eagleson, K., Kennedy, S. and Wang, Y. Identification of
a Survival‑Promoting Peptide in Medium Conditioned by Oxidatively
Stressed Cell Lines of Nervous System Origin. *J. Neurosci.* 18:
7047-7060, 1998.

84\. Mann, F., Zhukareva, V., Pimenta, A., Levitt, P. and Bolz, J.
Membrane-associated molecules guide limbic and non-limbic
thalamocortical projections. *J. Neurosci.* 18: 9409‑9419, 1998.

85\. Eagleson, K.L., Daigneau, L., and Levitt, P. The role of erbB
receptor signaling in cell fate decisions by cortical progenitors:
Evidence for a biased, lineage-based responsiveness to different
ligands. *Molec. Cell. Neurosci.* 12: 349-362, 1998.

**Publications (cont.)**

86\. Eagleson, K.L. and Levitt, P. Complex signaling responsible for
molecular regionalization of the cerebral cortex. *Cereb. Cortex* 9:
562-568, 1999.

87\. Burrows, R.C., Lillien, L. and Levitt, P. Mechanisms of progenitor
maturation are conserved in the striatum and cortex. *Dev. Neurosci.*
22: 7-15, 2000.

88\. Burrows, R.C., Levitt, P., and Shors, T.J. Postnatal decrease in
TGFα is associated with enlarged ventricles, deficient amygdaloid
vasculature and performance deficits. *Neuroscience* 96: 825-836, 2000.

89\. Rinaman, L., Levitt, P., Card, J.P. Progressive postnatal assembly
of limbic-autonomic circuits revealed by central transneuronal transport
of pseudorabies virus. *J. Neurosci*. 20: 2731-2741, 2000.

90\. Jones, L.B., Stanwood, G.D., Reinoso, B.S., Washington, R.A., Wang,
H.-Y., Friedman, E. and Levitt, P. In utero cocaine-induced dysfunction
of dopamine D~1~ receptor signaling and abnormal differentiation of
cerebral cortical neurons. *J. Neurosci.* 20: 4606-4614, 2000.

91\. Mirnics, K., Middleton, F.A., Marquez, A., Lewis, D.A. and Levitt,
P. Molecular characterization of schizophrenia viewed by microarray
analysis of gene expression in prefrontal cortex. *Neuron* 28: 53-67,
2000.

92\. Pimenta, A.F., Strick, P.L. and Levitt, P. Novel proteoglycan
epitope expressed in functionally discrete patterns in primate cortical
and subcortical regions. *J. Comp. Neurol.* 430: 369-388, 2001.

93\. Mirnics, K., Middleton, F.A., Stanwood, G.D., Lewis, D.A. and
Levitt, P. Disease-specific changes in regulator of G-protein signaling
4 (RGS4) expression in schizophrenia. *Molecular Psychiatry* 6: 293-301,
2001.

94\. Stanwood, G.D., Washington, R.A., and Levitt, P. Identification of
a sensitive period of prenatal cocaine exposure that alters the
development of the anterior cingulate cortex. *Cerebral Cortex* 11:
430-440, 2001.

95\. Powell, E.M., Mars, W.M., and Levitt, P. Hepacocyte growth
factor/scatter factor is a motogen for interneurons migrating from the
ventral to dorsal telencephalon. *Neuron* 30: 79-89, 2001.

96\. Stanwood, G.D., Washington, R.A., Shumsky, J.S. and Levitt, P.
Prenatal cocaine exposure produces consistent developmental alterations
in dopamine-rich regions of the cerebral cortex. *Neuroscience* 106:
5-14, 2001.

97\. Eagleson, K.L., Fairfull, L.D., Salton, S.R.J., and Levitt, P.
Regional differences in neurotrophin availability regulate selective
expression of VGF in the developing limbic cortex. *J. Neurosci.* 21:
9315-9324, 2001.

98\. Middleton, F.A., Mirnics, K., Pierri, J.N., Lewis, D.A., and
Levitt, P. Gene expression profiling reveals alterations of specific
metabolic pathways in schizophrenia. *J. Neurosci.* 22: 2718-2729, 2002.

99\. Gil, O.D., Zhang, L., Chen, S., Ren, Y.Q., Pimenta, A., Zanazzi,
G., Hillman, D., Levitt, P**.** and Salzer, J.L. Complementary
expression and heterophilic interactions between IgLON family members
neurotrimmin and LAMP. *J. Neurobiol.* 51:190-204, 2002.

100\. Chowdari, K.V., Mirnics K., Semwal, P., Wood, J., Lawrence, E.,
Bhatia, T., Deshpande, S.N., Thelma, B.K., Ferrell, R.E., Middleton,
F.A., Devlin, B.**,** Levitt, P., Lewis, D.A., Nimgaonkar, V.L.
Association and linkage analyses of *RGS4* polymorphisms in
schizophrenia. *Human Molec. Genetics* 11(12):1373-80, 2002.

**Publications (cont.)**

101\. Uziel, D., Muhlfriedel S., Zarbalis, K., Wurst, W., Levitt, P.,
Bolz, J. Miswiring of limbic thalamocortical projections in the absence
of ephrin-A5. *J. Neurosci.* 22(21): 9352-9357, 2002.

102\. Pongrac, J., Middleton F., Levitt P., Lewis D.A., Mirnics K. Gene
expression profiling with DNA microarrays: Advancing our understanding
of psychiatric disorders. *Neurochem Res.* 10:1047-1061, 2002.

103\. Powell, E.M., Campbell, D.B., Stanwood, G.D., Davis, C., Noebels,
J.L., and Levitt, P. Genetic Disruption of cortical interneuron
development causes region-and GABA cell type-specific deficits,
epilepsy, and behavioral dysfunction. *J. Neurosci* 23(2): 622-631,
2003.

**REVIEWS, INVITED PUBLISHED PAPERS, CONFERENCE AND SYMPOSIA
PROCEEDINGS, MONOGRAPHS, BOOKS, BOOK CHAPTERS**

1\. Levitt, P. and Moore, R.Y. (1979). Catecholamine innervation of the
developing neocortex in rat. In E. Usdin (Ed.), *Catecholamines: Basal
and Clinical Frontiers* (pp. 809-81). Pergamon Press.

2\. Levitt, P.(1982). The central monoamine neuron systems: Their
organization in the developing and mature primate brain and the genetic
regulation of their terminal fields. In A. J. Friedhoff and T.N. Chase
(Eds.), *Adv. in Neurology Vol. 35, Tourette Syndrome* (pp. 41-59). New
York: Raven Press.

3\. Levitt, P., Rakic, P. and Goldman-Rakic, P. (1984). Comparative
assessment of monoamine afferents in mammalian cerebral cortex. In L.
Descaries, T. Reader, and H. Jasper (Eds.), *Monoamine Innervation of
Cerebral Cortex* (pp. 41-59). New York: Alan R. Liss, Inc.

4\. Horton, H.L. and Levitt, P**.** (1986). Developmental studies with a
specific cell surface marker for limbic system neurons. In H.C. Slavkin
(Ed.), *Progress in Developmental Biology Part A* (pp. 111-114)*.* New
York: Alan R. Liss, Inc.,

5\. Levitt, P., Pawlak-Byczkowska, E., Horton, H.L. and Cooper, V.
(1986). Assembly of functional systems in the brain: Molecular and
anatomical studies of the limbic system. In C.J. Epstein (Ed.),
*Neurobiology of Down Syndrome* (pp. 195-209). New York: Raven Press.

6\. Hockfield, S., Carlson, S., Evans, C., Levitt, P., Pintar, J. and
Silverstein, L. (1994). *Molecular Probes of the Nervous System.* New
York: Cold Spring Harbor Press.

7\. Levitt, P. and Murphy, E.H. (1994). Events in central nervous system
development as the bases for susceptibility to neurotoxicity. In L.W.
Chang, (Ed.), *Principles of Neurotoxicology* (pp. 681-698). New York:
Marcel Dekker Inc.

8\. Levitt, P. (1994). Experimental approaches that reveal principles of
cerebral cortical development. In M.S. Gazzaniga (Ed.), *The Cognitive
Neurosciences* (pp. 147-163). New York: MIT Press.

**Publications (cont.)**

9\. Levitt, P., Ferri, R.T. and Eagleson, K. (1995). Molecular
contributions to cerebral cortical specification. In C. Blakemore (Ed.),
*Development of the Cerebral Cortex: Ciba Foundation Symposium 193* (pp.
200-213). London: Ciba Foundation Press.

10\. Levitt, P., Barbe, M.F. and Eagleson, K.E. (1997). Patterning and
specification of the cerebral cortex. *Ann. Rev. Neurosci.* 20: 1-24.

11\. Levitt, P. (1998). Neurodevelopment and Adult Psychopathology.
Matcheri S.Keshavan and Robin M. Murray (Eds.). *TINS.* 21: 130-131.

12\. Levitt, P. (1998). Prenatal effects of drugs of abuse on brain
development. *Drug and Alcohol Dependence* 51: 109-125.

13\. Levitt, P., Reinoso, B. and Jones, L. (1998). The critical impact
of early cellular environment on neuronal development. *Prev. Med*. 27:
180-183.

14\. Levitt, P. (1999). Molecular determinants of regionalization of the
forebrain and cerebral cortex. In M.S. Gazzaniga (Ed.), *The Cognitive
Neurosciences* (2nd ed., pp. 23-32)*.* New York*:* MIT Press.

15\. Levitt, P. and Pimenta, A. (1999). The Limbic system-associated
membrane protein. In T. Kreis and R. Vale (Eds.), *Guidebook to the
Extracellular Matrix, Anchor, and Adhesion Proteins* (pp. 224-226). New
York: Oxford University Press.

16\. Levitt, P. (1999). Development of the vertebrate nervous system. In
M.T.T. Wong-Riley (Ed.), *Neuroscience Secrets, 3* (pp. 46-57).
Philadelphia: Hanley & Belfus, Inc.

17\. McLaughlin, B. and Levitt, P. (1999). Molecular basis of
neurological disease. In M.T.T. Wong-Riley (Ed.), *Neuroscience Secrets,
23* (pp. 349-356). Philadelphia: Hanley & Belfus, Inc.

18\. Levitt, P. and Eagleson, K.L. (2000). Regionalization of the
cerebral cortex: Developmental Mechanisms and Models. In H. Karten and
Z. Molnar (Eds), *Evolutionary Development of the Cerebral Cortex:
Novartis Foundation Symposium 228* (pp. 173-187). London: Wiley & Sons.

19\. Mirnics, K., Middleton, F., Lewis, D.A. and Levitt, P. (2001).
Analysis of complex brain disorders with gene expression microarrays:
schizophrenia as a disease of the synapse. *TINS* 8: 479-486.

20\. Mirnics, K., Middleton, F.A., Lewis, D.A. and Levitt, P. (2001).
Delineating novel signature patterns of altered gene expression in
schizophrenia using gene microarrays. *The Scientific World* 1: 114-116.

21\. Stanwood, G.D. and Levitt, P. (2001). The effects of cocaine on the
developing nervous system. In C. Nelson and M. Luciana (Eds.), *Handbook
of Developmental Cognitive Neuroscience* (pp. 519-536). Cambridge, MA:
MIT Press.

22\. Stanwood, G.D. and Levitt, P. (2001). Prenatal cocaine exposure as
a risk factor for later developmental outcomes**.** *JAMA* 286: 46-47.

23\. Mirnics, K., Middleton, F.A., Lewis, D.A. and Levitt, P. (2001).
The human genome: Gene expression profiling and schizophrenia. *Am. J.
Psychiatry* 158: 1384.

24\. Mirnics, K., Lewis, D.A. and Levitt, P. (2001). DNA microarrays and
human brain disorders. In H.R. Chin and S.O. Moldin (Eds.), *Methods in
Genomic Neuroscience, 8* (pp. 171-204). Boca Raton, FL: CRC Press.

25\. Lewis, D.A. and Levitt, P. (2001). Schizophrenia as a disorder of
neurodevelopment. *Ann. Rev. Neurosci*. 25:409-432.