Amendment #2

to RFP NIH-NIAID-DMID-06-10

**Pathogen Functional Genomics Resource Center (PFGRC)**

+-----------------------------------+-----------------------------------+
| **Amendment to Solicitation       | NIH-NIAID-DMID-06-10              |
| No.:**                            |                                   |
+-----------------------------------+-----------------------------------+
| **Amendment No.:**                | 2                                 |
+-----------------------------------+-----------------------------------+
| **Amendment Date:**               | November 4, 2005                  |
+-----------------------------------+-----------------------------------+
| **RFP Issue Date:**               | September 15, 2005                |
+-----------------------------------+-----------------------------------+
| **Proposal Due Date:**            | December 15, 2005 (unchanged)     |
+-----------------------------------+-----------------------------------+
| **Issued By:**                    | Robert J. Singman\                |
|                                   | Contracting Officer\              |
|                                   | DHHS/NIH/NIAID\                   |
|                                   | Office of Acquisition\            |
|                                   | 6700-B Rockledge Drive\           |
|                                   | Room 3214, MSC 7612\              |
|                                   | Bethesda, Maryland 20892-7612     |
+-----------------------------------+-----------------------------------+
| **Point of Contact:**             | Robert J. Singman, Contracting    |
|                                   | Officer                           |
|                                   |                                   |
|                                   | 301-451-2607                      |
|                                   |                                   |
|                                   | <rsingman@niaid.nih.gov>          |
+-----------------------------------+-----------------------------------+
| **Name and Address of Offeror:**  | To All Offerors                   |
+-----------------------------------+-----------------------------------+

The hour and date for receipt of the offeror HAS NOT BEEN EXTENDED.
Offerors shall acknowledge receipt of this amendment by noting, on the
face page of the original technical and business proposal, that the
offer has been prepared in accordance with the original solicitation and
all its amendments. Failure of the offeror to submit this
acknowledgement may result in the rejection of your offer.

Purpose of Amendment: To replace Section L1.c. on page 31 and to replace
the table in Attachment 4 on page 93 of the subject RFP.

Section L.1.c is replaced with the following:

c\. **TYPE OF CONTRACT AND NUMBER OF AWARD(S)**

> It is anticipated that One Award will be made from this solicitation
> and that the award will be made on or about September 1, 2006.
>
> It is anticipated that the award from this solicitation will be a
> multiple-year cost reimbursement completion type contract for a period
> of performance of five years, and that incremental funding will be
> used \[see Section L.2.c. Business Proposal Instructions\].

The table in Attachment 4 [Packaging and Delivery of the
Proposal]{.underline} on page 93 of the subject RFP is replaced. The
replacement table is attached to this amendment.

End of Amendment #2 to RFP NIH-NIAID-DMID-06-10

+------------------+----------------------------------+---------------+
| **Document**     | Number of Copies                 | Page Limits   |
+------------------+----------------------------------+---------------+
| Technical        | **[PAPER]{.underline}**          | Limited to    |
| Proposal &       |                                  | not-to-exceed |
| Appendices       | One (1) unbound SIGNED ORIGINAL. | 150 pages     |
|                  |                                  |               |
|                  | Twenty (20) unbound COPIES       |               |
|                  |                                  |               |
|                  | **[ELECTRONIC FILES ON           |               |
|                  | CD]{.underline}**                |               |
|                  |                                  |               |
|                  | Fifteen (15) Compact Disks       |               |
|                  | containing an electronic copy of |               |
|                  | the Technical Proposal in a      |               |
|                  | Portable Document Format (PDF).  |               |
|                  | 1 file on each disk.             |               |
+------------------+----------------------------------+---------------+
| **Business       | [PAPER]{.underline}              | N/A           |
| Proposal**       |                                  |               |
|                  | One (1) unbound SIGNED ORIGINAL. |               |
|                  |                                  |               |
|                  | Five (5) unbound COPIES          |               |
|                  |                                  |               |
|                  | **[ELECTRONIC FILES ON           |               |
|                  | CD]{.underline}**                |               |
|                  |                                  |               |
|                  | Ten (10) Compact Disks           |               |
|                  | containing an electronic copies  |               |
|                  | of the Business Proposal in a    |               |
|                  | Portable Document Form (PDF). 1  |               |
|                  | PDF file on each disk.           |               |
+------------------+----------------------------------+---------------+
| **Breakdown of   | Attachment 13 of SECTION J       | N/A           |
| Proposed         | should be submitted also as a    |               |
| Estimated Cost** | separate excel file on the       |               |
|                  | Business Proposal Compact Disks. |               |
+------------------+----------------------------------+---------------+