Curriculum Vitae

**Name:** **Maria N. Garnovskaya, Ph.D.**

**Laboratory Address:** 401 Strom Thurmond **Phone:** 843 789-6774

Biomedical Center 843 789-6784

114 Doughty St. **Fax:** 843 876-5129

Ralph H. Johnson VA Medical Center

Charleston, S.C.,29403

**Office Address:** 829 CSB, Div. of Nephrology, **Phone:** 843 792-2939

Department of Medicine,

Medical University of South Carolina, **Fax:** 843 792-8399

96 Jonathan Lucas St, **E-Mail:** garnovsk@musc.edu

Charleston, S.C., 29425

**Education:**

[Years]{.underline} [Institution/Location]{.underline}
[Degree]{.underline}

1973-1977 Leningrad State University, St.Petersburg, Russia B.S.,Biology

1977-1979 Leningrad State University, St.Petersburg, Russia M.S.,
Biology/

Biochemistry

1979-1983 I.M.Sechenov Institute of Evolutionary Ph.D., Biology/

Physiology and Biochemistry, USSR Academy Biochemistry

of Sciences, St.Petersburg, Russia

**Internship:** Not Applicable

**Post Doctoral and Research Experience:**

[Years]{.underline} [Place]{.underline} [Position]{.underline}

1981-1983 I.M. Sechenov Institute, St.Petersburg,

Russia Research Assistant

1983-1986 I.M. Sechenov Institute, Russia Research Associate

1990-1991 Syracuse University, Dept. of Physics,

Syracuse, N.Y., USA Visiting Professor

1991-1993 Syracuse University, Biophysical Group,

Syracuse, N.Y., USA Research Associate

1993-1996 Duke University, Dept. of Medicine,

Durham, N.C., USA Research Associate

**Specialty/Board Certification:** Not Applicable

**Licensure:** Not Applicable

**Military Service:** None

**Faculty Appointments:**

[Years]{.underline} [Rank]{.underline} [Institution]{.underline}
[Department]{.underline}

1986-1989 Junior Scientific Researcher I.M.Sechenov Institute
Biochemistry

(Equivalent of Assistant Professor)

1989-1992 Scientific Researcher I.M.Sechenov Institute Biochemistry

(Equivalent of Associate Professor)

1996-2003 Assistant Professor of Medicine MUS C Medicine

1999-present Research Health Scientist Ralph H. Johnson VA Medical
Center

2003-present Associate Professor of Medicine MUS C Medicine

**Administrative Appointments:**

[Years]{.underline} [Description]{.underline} [Institution]{.underline}
[Department]{.underline}

1988-1991 Deputy Laboratory Chief I.M.Sechenov Institute Biochemistry

Laboratory of Molecular Basis Russia

of Sensory Reception

**Hospital Appointments/Privileges:** Not Applicable

**Membership in professional/scientific societies:**

1999-present Member, American Society for Biochemistry and Molecular
Biology

05/2007-07/2008 Member, American Heart Association

**Editorial Positions:** None

**Extramural Grants:**

As Principal Investigator

[Years]{.underline} [Organization]{.underline} [Description]{.underline}
[Award amount]{.underline}

1998- Department of Veterans Awarded Merit Review Entry Program
\$294,400

2001 Affairs, Washington DC for proposal: *Signaling Pathway of the
(62.5% effort) Activation of the Na^+^/H^+^ Exchanger by Osmotic Shock.*

2002- Department of Veterans Awarded Merit Review Type 1 proposal:
\$527,700

2005 Affairs, Washington DC *Early Regulation of the Retinoblastoma (75%
effort) Gene Product in Vascular Smooth Muscles*

2006- Department of Veterans Awarded Merit Review Type 1 proposal:
\$837,200

2010 Affairs, Washington DC *Integrin and GPCR-Induced Signaling in*

*(50% effort) Vascular Smooth Muscles Cells.*

2006- AHA, Mid-Atlantic Affiliate Awarded Grant-in Aid:
*Metalloproteinases*

2008 (*30% effort*) *and Epidermal Growth Factor Receptor* \$132,000

*Transactivation by the Bradykinin B2*

*Receptor in Kidney Cells*

As Co-Investigator

[Years]{.underline} [Organization]{.underline} [Description]{.underline}

> 1999- Department of Veterans Awarded Co-investigator for proposal:
>
> 2002 Affairs, Washington DC *Mechanisms of Bradykinin Inhibition of*
>
> > *(10% effort) Renal Absorption* Merit Award (PI=Dr. D. Ploth).
>
> 2001*-* Department of Health Awarded Co-Principal-investigator for
> proposal:
>
> 2006 and Human Services *G Protein Regulation of NHE Activity*
>
> > *(25% effort)* (PI=Dr. J. Raymond, direct cost: \$1,150,000).
>
> 2005- Department of Veterans Awarded Co-investigator for proposal:
>
> 2009 Affairs, Washington DC *Inflammatory Mediators of Renal
> Diseases.*
>
> VA REAP (PI Raymond and Gilkeson)

**Intramural Grants:**

[Years]{.underline} [Organization]{.underline} [Description]{.underline}
[Award amount]{.underline}

1996- Medical University of Awarded URC grant for project: \$18,000

1997 South Carolina *Signal* *transduction pathways in cellular*
*regulatory volume increase.*

**Honors and Awards:**

[Date]{.underline} [Organization]{.underline} [Description]{.underline}

1988 I.M.Sechenov Institute Individual Award for Leningrad, Russia
Outstanding Research: 1^st^ Prize

1990 I.M.Sechenov Institute Individual Award for Leningrad, Russia
Outstanding Research: 2 ^nd^ Prize

**Academic Committee Activities:**

1999-2002 Chair of Biosafety Committee Ralph H. Johnson VA Medical
Center

2001-2002 Member of Research Service Ralph H. Johnson VA Medical Center

Space Subcommittee

2002-present Member of Biosafety Committee Ralph H. Johnson VA Medical
Center

2007-2010 Member of Peer Review Committee American Heart Association,
Mid-

Molecular Signaling Study Section Atlantic Affiliate

**Major Teaching Responsibilities:**

1983-1991 I.M. Sechenov Institute, Laboratory of Supervised 4 graduate

Molecular Basis of Sensory Reception students

1991-1993 Biophysical Group, Dept. of Physics Trained 3 graduate
students to

Syracuse University assist with biochemical methods

1993-1996 Renal Signal Transduction Lab Supervised the laboratory

> at Duke University Medical Center experience of clinical fellows

1996-present Medical University of South Carolina

Nephrology Lab

Participating faculty member on the Glomerular Diseases training grant

Qualifying investigator in the REAP program (VA-sponsored training
grant)

Supervise the laboratory training of clinical fellows, graduate
students, and summer students to assist with biochemical and molecular
biological methods

Supervise the day to day use of the microphysiometry shared resource at
the Charleston Ralph H. Johnson VAMC. Provided assistance with
microphysiometry for several Laboratories at MUSC.

Give a didactic lecture on the use of FLIPR and Microphysiometer as part
of the Advanced cell Biology Course at the MUSC

Give lectures on Signal Transduction as part of the Nephrology
Fellowship program

**Major Research Interests:**

Molecular regulation of growth signals in fibroblasts, smooth muscle,
and kidney cells.

Signal transduction in cell volume regulation.

The mechanisms of regulation of sodium/proton (Na^+^/H^+^) exchange in
different cell types.

Regulation of cell cycle in vascular smooth muscle cells -- role of
integrins.

**Invited Lectures:** See abstract list

# Publications in Refereed Journals:

1.  E. Kh. Safaryan and **M. N. Garnovskaya**. Chemoreceptor structures
    of the catfish *Ictalurus nebulosus*: Isolation and properties of
    plasmatic membranes from barbles. *J. Evol. Biochem. & Physiol.*
    1981; **17**:248-252.

2.  **M. N. Garnovskaya,** I. L. Dumler, R. N. Etingof. The influence of
    nucleotide triphosphates on cyclic nucleotide phosphodiesterase:
    Role of protein modulators. *Biochemistry (Biokhimiya)* 1982;
    **47**:181-185.

3.  **M. N. Garnovskaya**, I. L. Dumler, R. N. Etingof. Role of cyclic
    nucleotide phosphodiesterase in the action of estradiol in uterine
    tissue. *Bull. Exp. Biol. & Med.* 1982; **93**:831-834 .

4.  R. N. Etingof, **M. N. Garnovskaya,** A. A. Usova, I. L. Dumler.
    Effect of 17-β- estradiol on 3',5'-AMP-phosphodiesterase activity in
    rat uterus: The role of hormonal receptor and guanyl nucleotide
    binding proteins. *Ukrains. Biokhim. Zh. (Russian)* 1983; **55**:
    53-57.

5.  **M. N. Garnovskaya.** The relationship between cyclic nucleotide
    phosphodisterase and β-estradiol receptors in uterine tissue.
    *Ph. D. Thesis* I. M. Sechenov Institute, Leningrad 1983.

6.  R. N. Etingof, I. L. Dumler, **M. N. Garnovskaya**, S. N. Kalinina.
    Estradiol receptor and cyclic nucleotide phosphodiesterase:
    Functional relationship, possible role of guanine nucleotide binding
    proteins. *Biochem. Intern.* 1984; **9**: 229-236 .

7.  I. L. Dumler, **M. N. Garnovskaya**, N. O. Artem'ev, R. N. Etingof.
    Comparative immunochemical analysis of various cyclic nucleotide
    phosphodiesterases. *Biochemistry (Biokhimiya)* 1984; **49**:
    1478-1482.

8.  **M. N. Garnovskaya**, I. L. Dumler. Participation of the estradiol
    receptor in the hormonal inhibition of cyclic nucleotide
    phosphodiesterase in the uterus. *Ukrains. Biokhim. Zh. (Russian)*
    1984; **56**: 633-638.

9.  **M. N. Garnovskaya**, I. L. Dumler, G. A. Savitskii. Effect of
    17-β-estradiol on 3',5'-AMP-cyclic phosphodiesterase of uterine
    tissue in myoma. *J. Obst. Gynecol. (Russian)* 1986; **2**: 20-22.

10. N. O. Artem'ev, **M. N. Garnovskaya**, I. L. Dumler, R. N. Etingof.
    Detection of a peptide activator of cyclic nucleotide
    phosphodiesterase in uterine tissue. *Biochemistry (Biokhimiya)*
    1987; **52**: 1240-1246.

11. N. O. Artem'ev, **M. N. Garnovskaya**, I. L. Dumler. Purification
    and properties of cyclic nucleotide phosphodiesterase of uterine
    tissue. *Biochemistry (Biokhimiya)* 1988; **53**:1134-1139.

12. S. A. Shelkovnikov, L. A. Starshinova, **M. N. Garnovskaya**, N. O.
    Artem'ev, R. N. Etingof, I. L. Dumler. Cyclic nucleotide
    phosphodiesterase activator peptide: Effect on contractility of
    muscles. *Bull. Exp. Biol. & Med.* 1988; **106**: 1670-1673.

13. V. V. Gurevich, S. A. Zozulya, T. A. Zvyaga, M. Yu. Natochin, E. P.
    Shirokova, **M. N. Garnovskaya**, I. L. Dumler, B. E.
    Shmukler, N. V. Korotkova. Functional activity of visual rhodopsin
    expressed *in vitro*. *Biol. Membr. (Russian)* 1989; **6**: 647-649.

14. S. N. Korolkov, **M. N. Garnovskaya**, A. S. Basov, I. L. Dumler.
    The functional similarity of vertebrate rhodopsin and of a
    photosensitive pigment from the unicellular flagellate alga
    *Chlamydomonas reinhardtii.* *J. Evol. Biochem. & Physiol.
    (Russian)* 1989; **25**: 777-780.

15. S. A. Zozulya, V. V. Gurevich, T. A. Zvyaga, I. L. Dumler, **M. N.
    Garnovskaya**, B. E. Shmukler, M. Yu. Natochin, E. P.
    Shirokova, P. R. Badalov. *In vitro* synthesis of visual rhodopsin
    for a protein engineering study. *J. Prot. Chem.* 1989; **8**:
    380-382.

16. L. Dumler, S. N. Korolkov, **M. N. Garnovskaya**, E. V.
    Parfenova, R. N. Etingof. The system of photo-& pheromone signal
    transduction in unicellular eukaryots. *J. Prot. Chem.* 1989; **8**:
    387-389.

17. **M. N. Garnovskaya**, G. A. Savitskii. Peptide-activator of cyclic
    nucleotide phosphodiesterases in the rat and human uterine tissue.
    *Ukrains. Biokhim. Zh. (Russian)* 1989; **61**: 100-103.

18. **M. N. Garnovskaya**, A. V. Tret'yakov, M. N. Maslova, R. N.
    Etingof. Aminobenzoic acid derivatives as specific inhibitors of
    cyclic nucleotide phosphodiesterase in the rat uterus. *Ukrains.
    Biokhim. Zh. (Russian)* 1990; **62**:97-101.

19. **M. N. Garnovskaya**, N. O. Artem'ev, I. L. Dumler, R. N. Etingof.
    Is the γ-subunit of 3',5'-cyclic GMP phosphodiesterase of the rod
    outer segments unique? A new protein with similar properties. *Biol.
    Membr. (Russian)* 1990; **7**:101-105.

20. S. A. Zozulya, V. V. Gurevich, T. A. Zvyaga, E. P. Shirokova, I. L.
    Dumler, **M. N. Garnovskaya**, M. Yu. Natochin, B. E.
    Shmuckler, P. R. Badalov. Functional expression *in vitro* of bovine
    visual rhodopsin. *Prot. Engineering* 1990; **3**:453-458.

21. V. V. Gurevich, S. A. Zozulya, E. P. Shirokova, T. A. Zvyaga,
    **M. N. Garnovskaya**, I. L. Dumler, P. R. Badalov, M. Yu.
    Natochin, I. D. Pokrovskaya, B. E. Shmukler. Synthesis of visual
    rhodopsin in a cell-free translation system. II. Functional
    properties of recombinant rhodopsin and its mutant forms. *Sov. J.
    Bioorg. Chem.* 1990; **16**: 303-308.

22. S. N. Korolkov, **M. N. Garnovskaya**, A. S. Basov, A. S.
    Chunaev, I. L. Dumler. The detection and characterization of
    G-proteins in the eyespot of *Chlamydomonas reinhardtii*. *FEBS
    Lett.* 1990; **270**: 132-134.

23. V.V.Gurevich, S.A.Zozulya, E.P.Zerf, I.D.Pokrovskaya,
    **M.N.Garnovskaya**, I.L. Dumler, M.P. Rychkova, T.A. Obukhova.
    Bovine visual rhodopsin: Amino acid substitutions asp-83-asn and
    glu-134-gln prevent activation of cyclic GMP phosphodiesterase.
    *Biomed. Sci.* 1990; **1**: 527-530.

24. L. Dumler, S. N. Korol'kov, **M. N. Garnovskaya**, E. V.
    Parfenova, M. G. Efimova, Yu. V. Chistyakova, R. N. Etingof.
    Evolutionary aspects of the molecular mechanism of the transmission
    of sensory signals. *J. Evol. Biochem. & Physiol.* 1991; **27**:
    102-109.

25. N. O. Artem'ev, **M. N. Garnovskaya**, I. A. Ostapenko, M. P.
    Rychkova. A native model for function and structure studies of
    cyclic GMP-phosphodiesterase photoreceptor. *Biol. Membr. (Russian)*
    1991; **8**:85-87.

26. V. V. Gurevich, I. D. Pokrovskaya, **M. N. Garnovskaya**, I. L.
    Dumler, S. A. Zozulya. Proper cotranslational insertion of visual
    rhodopsin into the lipid bilayer occurs in the absence of protein
    translation machinery. *Biomed. Sci.* 1991; **2**:187-192.

27. J. G. Milheron, S. J. Casanas, J. M. Arthur, **M. N.
    Garnovskaya**, T. W. Gettys, J. R. Raymond. Human 5-HT1A receptor
    expressed in insect cells activates endogenous Goα-like G-proteins.
    *J. Biol. Chem.* 1994; **269**:12954-12962.

28. C. G. Nebigil, **M. N. Garnovskaya**, R. F. Spurney, J. R. Raymond.
    Identification of a rat glomerular mesangial cell mitogenic 5-HT2A
    receptor. *Am. J. Physiol.* 1995; **268**:F122-F127.

29. C. G. Nebigil, **M. N. Garnovskaya**, S. J. Casanas, J. G.
    Mulheron, E. M. Parker, T. W. Gettys, J. R. Raymond. Agonist-induced
    desensitization and phosphorylation of human 5-HT1A receptor
    expressed in Sf9 insect cells. *Biochemistry* 1995; **34**:
    11954-11962.\*

30. **M. N. Garnovskaya**, C. G. Nebigil, J. M. Artur, R. F.
    Spurney, J. R. Raymond. 5-Hydroxytriptamine~2A~ receptors expressed
    in rat renal mesangial cells inhibit cyclic AMP accumulation . *Mol.
    Pharmacol.* 1995; **48**: 230-237.

31. **M. N. Garnovskaya**, T. van Biesen, B. E. Hawes, S. G.
    Casanas-Ramos, R. J. Lefkowitz, J. R. Raymond. Ras-dependent
    activation of fibroblast mitogen-activated protein kinase by 5-HT1A
    receptor *via* a G protein *βγ*-subunit-initiated pathway.
    *Biochemistry* 1996; **35**: 13716-13722.

32. **M. N. Garnovskaya**, T.W. Gettys, T. van Biesen, J.K. Chuprin,
    V.Prpic, J. R. Raymond. G-protein-coupled 5-HT1A receptor activates
    Na^+^/H^+^ exchange in CHO-K1 cells through Giα2 and Giα3. *J. Biol.
    Chem.* 1997; **272**:7770-7776.

33. **M. N. Garnovskaya**, Y. V. Mukhin, J. R. Raymond. Rapid activation
    of sodium-proton exchange and extracellular signal-regulated protein
    kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves
    distinct signaling cascades. *Biochemical J*. 1998; **330**:489-495.

34. V. Prpic, G.J. Fitz, Yu Wang, J.R. Raymond, **M.N. Garnovskaya**,
    R.A. Liddle. Inhibition of Na^+^/H^+^ exchange stimulates
    cholecystokinin secretion in STC-1 cells. *Am. J. Physiol.* 1998;
    **275**: G689-G695.

35. Della Rocca, G.J., Mukhin, Y.V., **Garnovskaya, M.N.,** Daaka, Y.,
    Clark, G., Luttrell, L.M., Lefkowitz, R.J., and Raymond, J.R.
    Serotonin 5-HT1A receptor-mediated Erk activation requires
    calcium/calmodulin-mediated receptor endocytosis. *J. Biol. Chem.*
    1999; **274**: 4749-4753.

36. R. Chen, E.L. Greene, G. Collinsworth, J. Grewal, O. Houghton, H.
    Zeng, **M.N. Garnovskaya**, R.V. Paul, and J.R. Raymond. Enrichment
    of transiently transfected mesangial cells by cell sorting after
    cotransfection with green fluorescent protein. *Am. J. Physiol.*
    1999; **276**: F777-F785.

37. J.S.Grewal, Y.V. Mukhin, **M.N. Garnovskaya**, J.R. Raymond, and
    E.L. Greene. Serotonin 5HT2A receptor induces TGF-β1 mRNA and
    protein in rat mesangial cells *via* ERK: proliferative and fibrotic
    signals. *Am. J. Physiol.* 1999; **276**: F922-F930.

38. K.P. Becker, **M.N. Garnovskaya**, T.W. Gettys, P.V. Halushka.
    Coupling of TXA~2~ receptor isoforms to G~α13~: Effects on ligand
    binding and signalling. *Biochimica et Biophysica Acta* 1999;
    **1450**:288-296.

39. J.R. Raymond, Y.V. Mukhin, T.W. Gettys, and **M.N. Garnovskaya.**
    The recombinat 5-HT1A receptor: G protein coupling and signalling
    pathways. *British J. of Pharmacology* 1999; **127**:1751-1764.

40. **M. N. Garnovskaya**, Y. V. Mukhin and J. R. Raymond. Role for
    janus kinase in the activation of sodium-hydrogen exchange by
    osmotic shock. *Miami Nature Biotechnology Short Reports* **10**, 37
    (1999).

41. Y.V. Mukhin, **M.N. Garnovskaya**, G. Collinsworth,
    DK.Pendergrass, T. Nagai, S. Pinckney, J.S.Grewal, E.L. Greene, and
    J.R. Raymond. 5-HT1A receptor/ G~i~βγ stimulates mitogen-activated
    protein kinase *via* NAD(P)H oxidase and reactive oxygen species
    upstream of Src in CHO fibroblasts. *Biochemical J*. 2000;
    **347**:61-67.

42. E.L.Greene, O. Houghton, G. Collinsworth, **M.N. Garnovskaya**, T.
    Nagai, T. Sajjad, V. Bheemanathini, J. Grewal, R.V.Paul, and J.R.
    Raymond. 5HT2A receptor stimulate mitogen-activated protein kinase
    *via* hydrogen peroxide generation in rat renal mesangial cells.
    *Am. J. Physiol.* 2000; **278**: F650-F658.

43. R. Chen, Y. Mukhin, **M.** **Garnovskaya**, T. Thielen, Y.
    Iijima, C. Huang, J.R. Raymond, M.E. Ullian, R.V. Paul. A Fully
    Functional Angiotensin II Type 1A Receptor-GFP Fusion Protein:
    Evidence for Agonist-Dependent Nuclear Translocation. *Am. J.
    Physiol.* 2000; **279**, F440-F448.

44. Y.V. Mukhin, T. Vlasova, A.A. Jaffa, G. Collinsworth, J.L. Bell,
    B.G. Tholanikunnel, T. Pettus, W. Fitzgibbon, D.W. Ploth, J.R.
    Raymond, and **M.N. Garnovskaya**. Bradykinin B~2~ receptors
    activate Na^+^/H^+^ exchange in mIMCD-3 cells *via* Janus kinase 2
    and Ca^2+^/calmodulin. *J. Biol. Chem.* **276**, 17339-17346 (2001).

45. J.R. Raymond, Y.V. Mukhin, A. Gelasco, J. Turner, G. Collinsworth,
    T.W. Gettys, J.S. Grewal, and **M.N. Garnovskaya**. Multiplicity of
    mechanisms of serotonin receptor signal transduction. *Pharmacol.
    Ther.* **92**, 179-212 (2001).

46. Mukhin YV, Garnovsky, E.A., Ullian, M.E., and **Garnovskaya MN**.
    Bradykinin B~2~ receptor activates extra-cellular signal regulated
    protein kinase in mIMCD-3 cells via epidermal growth factor receptor
    transactivation. *JPET* **304**, 968-977 (2003).

47. **Garnovskaya MN**, Mukhin YV, Vlasova T, and Raymond JR.
    Hypertonicity activates Na^+^/H^+^ exchange through Janus kinase 2
    and Calmodulin *J. Biol. Chem.* **278**,16908-16915 (2003).

48. D. Lefler, Y.V. Mukhin, T. Pettus, L.M. Fredrik Leeb-Lundberd,
    **M.N. Garnovskaya**, and J.R. Raymond. Jak2 and Ca2^+^/calmodulin
    are key intermediates for bradykinin B~2~ receptor-mediated
    activation of Na^+^/H^+^ exchange in KNRK and CHO cells. *ASSAY and
    Drug Development Technologies* **1**, 281-289 (2003).

49. **Garnovskaya MN**, Mukhin YV, Turner, J.H., Vlasova T, Ullian,
    M.E., and Raymond JR. Mitogen-induced activation of Na^+^/H^+^
    exchange in vascular smooth muscle cells involves Janus kinase 2 and
    calmodulin. *Biochemistry* **42**, 7178-7187 (2003).

50. Y.V. Mukhin, **M.N. Garnovskaya**, M.E. Ullian, and J.R. Raymond.
    ERK is regulated by sodium-proton exchanger in rat aortic vascular
    smooth muscle cells. *J. Biol. Chem.* **279**, 1845-1852 (2004).

51. **M.N. Garnovskaya**, Y.V. Mukhin, M.E. Ullian, B.G. Tholanikunnel,
    J.S.Grewal, and J.R. Raymond. Mitogen-Induced Rapid Phosphorylation
    of Serine^795^ of the Retinoblastoma Gene Product in Vascular Smooth
    Muscle Cells Involves ERK Activation*.* *J. Biol. Chem.* **279**;
    24899-24905 (2004).

52. Scholz D, McDermott P, **Garnovskaya M**, Gallien TN, Huettelmaier
    S, DeRienzo C, Cooper G. Microtubule-associated protein-4 (MAP-4)
    inhibits microtubule-dependent distribution of mRNA in isolated
    neonatal cardiocytes. *Cardiovascular Research* **71**; 506-516
    (2006)

53. Y.V. Mukhin, M. Gooz, and J.R. Raymond, and **M.N. Garnovskaya**.
    Collageneses 2 and 3 Mediate Epidermal Growth Factor Receptor
    Transactivation by Bradykinin B~2~ receptor in Kidney Cells. *JPET*
    **318**; 1033-1043 ( 2006).

54. Turner JH, **Garnovskaya MN,** Coaxum SD, Vlasova TM, Yakutovich MD,
    Lefler DM, and Raymond JR, Sr. Ca^2+^-calmodulin and Jak2 are
    Required for Activation of Sodium-proton Exchange by the Gi-coupled
    5-hydroxytryptamine~1A~ Receptor. *JPET* **320**; 314-322 ( 2007).

55. Turner JH, **Garnovskaya MN,** Raymond JR, Serotonin 5-HT~1A~
    receptor stimulates c-Jun N-terminal kinase and induces apoptosis in
    Chinese hamster ovary fibroblasts. *Biochimica et Biophysica Acta
    (BBA) - Molecular Cell Research* **1773**; 391-399 (2007).

56. Kramarenko II, Bunni MA, Morinelli TA, Raymond JR, and **Garnovskaya
    MN**. Identification of a Functional Bradykinin B~2~ Receptors
    Endogenously Expressed in HEK293 Cells. *Biochem Pharmacology*
    **77**; 269-276 (2009).

# Chapters in Books:

1\. Dumler I.L., **Garnovskaya M.N.**, Korolkov S.N., Parfenova E.V.,
and Etingof R.N. Molecular mechanisms of sensory signal transduction.
*In* *Intracellular Signalling (Russian).* Kostyuk P.G. and Ostrovsky
M.A. eds., 1990 Science Press, Moscow.

2\. Raymond JR, Turner JH, Gelasco A, Ayiku H, Coaxum S., Arthur JM and
**Garnovskaya MN**. 5-HT Receptor Signal Transduction Pathways. In: *The
Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics.*
Ed. Bryan Roth. 2005 The Humana Press, Inc. Totowa, NJ, USA.

3\. Turner JH, Coaxum SD, Gelasco AK, **Garnovskaya MN**, Raymond JR.
Calmodulin is a 5-HT Receptor Interacting and Regulatory Protein In:
Frontiers in Neuroscience. Serotonin Receptors in Neurobiology.
(Chattopadhyay, A. Ed.), (Nicolelis, M. and Simon, S. Series Eds.), 2007
CRC Press, Boca Raton, FLA, pp.61-80.

# Manuscripts in Press: 

None currently

**Manuscripts Submitted or in Revision:**

Mukhin Y.V., **Garnovskaya M.N.**, Bell J., Collinsworth G.P., Ploth,
D.W., and Raymond J.R. Bradykinin B~2~ receptor activation induces
multiple cellular responses in M-1 cortical collecting duct cells. In
Revision *AJP: Renal Physiology* (2007).

Gelasco AK, Tyson AM, Sweet GH, Andy JC, **Garnovskaya MN**, and Raymond
JR Indoxyl sulfate induces ERK mediated cell proliferation in rat
mesangial cells. In Revision *AJP: Renal Physiology* (2007).

Coaxum S, Gooz M, Baldys A, **Garnovskaya M**, and Raymond J

Epidermal Growth Factor Activates Na+/H+ Exchange in Podocytes through a
Mechanism that Involves Janus Kinase and Calmodulin. In Revision *BBA*
(2008).

**Manuscripts in Preparation:**

Kramarenko II, Bunni MA, Raymond JR, and **Garnovskaya MN**. Bradykinin
B~2~ Receptor Interacts with Integrin α5/β1 to Transactivate Epidermal
Growth Factor Receptor in Kidney Cells.

Bunni MA, Kramarenko II, Raymond JR, and **Garnovskaya MN**. Role of
Integrins in Angiotensin II-induced Proliferation of Vascular Smooth
Muscle Cells.

**Garnovskaya MN**. Serotonin 5-HT Receptor Signal Transduction: Focus
on 5- HT2C Receptors, a chapter in the book \"The Pathophysiology of
Central 5-HT2C Receptors\", to be published by Humana Press/Springer,
New York, USA (Dr. Giuseppe Di Giovanni, and Dr Esposito, Di Matteo Ed.)

# Selected Published Abstracts:

1a. **Garnovskaya M.N**., Dumler I.L., Etingof R.N. The pole of protein
modulators in ATP and GTP influence on the cyclic nucleotide
phosphodiesterase.*Proceedings of the 6^th^ Joint symposium of the
Biochemical societies of the GDR and the USSR.* Tallinn, p.52 (1981).

2a. **Garnovskaya M.N.**, Dumler I.L., Etingof R.N. Cyclic nucleotide
phosphodiesterase and steroid hormon reception. *Proceedings of the
16^th^ Meeting of the Federation of Experimental Biological Scientists.*
Moscow, p.168 (1984).

3a. **Garnovskaya M.N.**, Artemyev N.O., Dumler I.L. The detection in
the uterus of a new peptide-activator of cyclic nucleotide
phosphodiesterase. *Proceedings of the 7^th^ All-Union Meeting,
"Chemistry of Proteins and Peptides."* Tallinn, p.44 (1987).

4a. **Garnovskaya M.N.** The peptide activator of cyclic nucleotide
phosphodiesterases: possible physiological role. *Proceedings of the
7^th^ All-Union Meeting 'Cyclic Nucleotides and other second messengers
in enzyme regulation."* Petrozavodsk, (1988).

5a. Dumler I.L., **Garnovskaya M.N.**, Artemyev N.O., Etingof R.N. The
new protein inhibitor of cyclic GMP phosphodiesterase. *Proceedings of
the Conference "Purine Nucleosides and Nucleotides in Cell Signalling:
Targets for New Drugs."* Bethesda, MD, U.S.A., G-1 (1989).

6a. Gurevich V.V., Zozulya S.A., Zvyaga T.A., Dumler I.L., **Garnovskaya
M.N.**, Shmucler B.E., Natochin M., Shirokova E.P., Badalov P.R.
Functional analysis of site-directed mutations in visual rhodopsin.
*Proceedings of the 3^rd^ International Conference of Young Scientists
from Socialist Countries.* Prieros, GDR, p.24. (1989).

7a. **Garnovskaya M.N.** the role of the cyclic nucleotide
phosphodiesterases in steroid hormone action. *Proceedings of the
9^th^All-Union Meeting "Mechanism of Action of Mediators and Hormones on
Effector Cells."* Suzdal, p.84 (1989).

8a. Korolkov S.N., **Garnovskaya M.N.** Dumler I.L. Biochemical
evolution of photo-sensory systems: functional similarity of vertebrate
rhodopsin and photosensory pigment of *Chlamydomonas reinhardtii*..
*Proceedings of the 9^th^ All-Union Meeting "Mechanism of Action of
Mediators and Hormones on Effector Cells."* Suzdal, p.84 (1989).

9a. Zozulya S.A., Gurevich V.V., Zvyaga T.A., Dumler I.L., **Garnovskaya
M.N.**, Shmucler B.E., Natochin M., Shirokova E.P., Badalov P.R. *In*
*vitro* synthesis of visual rhodopsin for a protein engineering study.
*Proceedings of the Bilateral Symposium of the USSR -West Berlin:
"Receptors and Ion Channels",* West Berlin (1989).

10a. Dumler I.L., Korolkov S.N., **Garnovskaya M.N.**, Parfenova E.V.,
Etingof R.N. The systems of photo- and pheromone signal transduction in
unicellular eukaryotes. *Proceedings of the Bilateral Symposium of the
USSR - West Berlin: "Receptors and Ion Channels",* West Berlin (1989).

11a. **Garnovskaya M.N.**, Korolkov S.N., Gurevich V.V., Zozulya S.A.,
Pokrovskaya I.D., Dumler I.L. Structural and functional analysis of
visual rhodopsin: identification of domains interacting with transducin
in the process of photoexitation. *Proceedings of the 8^th^ Meeting of
the European Society for Neurochemistry.* Leipzig, (1990).

12a. Dumler I.L., Artemyev N.O., **Garnovskaya M.N.** cGMP
phosphodiesterase of retina rod outer segments: molecular mechanisms of
function. *Proceedings of the 9^th^ International Congress on Eye
Research.* Helsinki, p.3 (1990).

13a. Dumler I.L., Korolkov S.N., **Garnovskaya M.N.** Rhodopsin-like
pigment and G-proteins of *Chlamydomonas reinhardtii*. *Proceedings of
the 5^th^ International Conference on Retinal Proteins.* Dourdan,
(1992).

14a. Lipson E.D., Sineshchekov A.V., Chen X., **Garnovskaya M.N.**
Cellular physiology of phototropism in *Phycomyces*. *Proceedings of the
21^st^ Annual Meeting American Society for Photobiology.* Chicago,
(1993).

15a. Raymond J.R., Nebigil C.G., Gettys T.W. Arthur J.M., **Garnovskaya
M.N.** Interaction of an endogenous receptor kinase with human 5-HT1A
receptors in insect cells. Presented at the Annual Meeting of the
American Federation for Clinical Research, Baltimore, *Clin.Res*.
(1994).

16a. Nebigil C.G., Raymond J.R., Spurney R.F., **Garnovskaya M.N.**
Molecular cloning and multiple second messenger pathways of a 5-HT2
receptor expressed in rat mesangial cells. Presented at the Annual FASEB
Meeting, San Diego, *FASEB J.* 8:A87, (1994).

17a. Nebigil C.G., **Garnovskaya M.N.**, Casanas S., Parker E., Raymond
J.R. Agonist-induced phosphorylation and desensitization of 5-HT1A
receptors expressed in baculovirus-infected insect cells. Presented at
the International Congress of Pharmacology, Montreal, Canada, (1994).

18a. Liu X., Gao Y., **Garnovskaya M.N.**, Raymond J.R., Kebabian J.W.
Novel molecular probes for the 5-HT1A receptor. Presented at the 210^th^
Annual Meeting of the American Chemical Society, Chicago, (1995).

19a. Prpic V., **Garnovskaya M.N.**, Fitz J.G., Gettys T.W.,
Collinsworth G., Raymond J.R., Liddle R.A. Bombesin stimulates proton
efflux and CCK secretion in STC-1 cells. *Proceedings of the 9^th^
International Conference* *on Second* *Messengers and Phosphoproteins*,
Nashville, 371, p.132, (1995).

20a. Gao Y., Liu X., **Garnovskaya M.N.**, Raymond J.R., Kebabian J.W.
Interactions of (S)-UH-301 derivatives with recombinant 5-HT1A
receptors. Presented at the Annual Meeting of the Society for
Neuroscience, San Diego, (1995).

21a. **Garnovskaya M.N.**, van Biesen T., Hawes B., Lefkowitz R.J.,
Raymond J.R. Divergent pertussis toxin-sensitive pathways for 5-HT1A
receptor activation of NHE and ERK. Presented at the 29^th^ Annual
Meeting of the American Society of Nephrology, New Orleans, (1996).

22a. **Garnovskaya M.N.**, van Biesen T., Hawes B., Lefkowitz R.J.,
Raymond J.R. Specific α-subunits from the Gi/o/z family mediate acute
agonost-induced activation of NHE. Presented at the 29^th^ Annual
Meeting of the American Society of Nephrology, New Orleans, (1996).

23a. Raymond J.R., **Garnovskaya M.N.** Regulation of NHE-1
activity*via* Gi proteins. Presented at the Annual Meeting of the
Southern Kidney, Salt and Water Club, Longboat Key, Florida, (1996).

24a. Greene E.L., Collinsworth G., **Garnovskaya M.N.** Raymond J.R.
Renal mesangial cell 5-HT2A receptor activates mitogen-activated protein
kinases ERK1/ERK2 by an anti-oxidant-sensitive pathway. Presented at the
Annual Meeting of the American Society for Clinical Investigation,
Washington, D.C., *J.Investigative Med*. 45, 232S, (1997).

25a. Greene E.L., Collinsworth G., **Garnovskaya M.N.**, Grewal J.,
Sajjad T., Raymond J.R. Receptor activation of MAP kinases ERK1/ERK2
occurs by an anti-oxidant-sensitive mechanism. Presented at the Annual
Meeting of the California Oxidant Society, (1997).

26a. Raymond J.R., **Garnovskaya M.N.** Regulation of NHE-1 activity
*via* Gi proteins. Presented at the First Annual Meeting of
Microphysiometer and FLIPR Users Group, Paris, France, (1997).

27a. **Garnovskaya M.N.**, Mukhin Y.V., Raymond J.R. Shrinkage induced
activation of Na^+^/H^+^ exchange: in search of signaling intermediates
involved in regulatory volume increase in fibroblasts. *Proceedings of
the 33^d^ International Congress of Physiological Sciences,* St.
Petersburg, Russia, P025.02, (1997).

28a. Mukhin Y., Della Rocca G., Raymond J.R., **Garnovskaya M.N.**
Involvement of calmodulin in 5-HT~1A~ receptor-activation of mitogen
activated protein kinase and Na^+^/H^+^ exchange in fibroblasts.
Presented at the Annual FASEB Meeting, San Francisco, *FASEB J*. **12**:
A745, (1998).

29a. **Garnovskaya M.N.**, Mukhin Y.V., Ullian M.E., Raymond J.R.
Mitogen-induced activation of Na^+^/H^+^ exchange in vascular smooth
muscle cells involves Janus kinase. Presented at the Annual FASEB
Meeting, San Francisco, *FASEB J.* **12**:A744, (1998).

30a. Raymond J.R., Collinsworth G.P., Mukhin Y.V., **Garnovskaya M.N.**
Evaluating unusual G protein-coupled signals with the Cytosensor^TM^.
Presented at the Second International Cell Analysis Products Users
Meeting, Hilton Head, S.C., (1998).

31a. **Garnovskaya M.N.**, Collinsworth G.P., Raymond J.R., Ploth D.W.
Multiple receptors activate Na^+^/H^+^ exchange in mIMCD-3 cells.
Presented at the Second International Cell Analysis Products Users
Meeting, Hilton Head, S.C., (1998).

32a. Mukhin Y.V., Ullian M.E., Raymond J.R., **Garnovskaya M.N.**
Mitogens use different pathways to activate Na^+^/H^+^ exchange in
vascular smooth muscle cells. Presented at the Second International Cell
Analysis Products Users Meeting, Hilton Head, S.C., (1998).

33a. **Garnovskaya M.N.**, Mukhin Y.V., Raymond J.R. Role for Janus
kinase in the activation of sodium-hydrogen exchange by osmotic shock.
Presented at the Miami Nature Biotechnology Winter Symposia, Miami, FL,
February 6-10 (1999); *MNB Short Reports* **v.10**, 37 (1999).

34a. Mukhin Y.V., **Garnovskaya M.N.**, Collinsworth G.P., Greene E.L.,
and Raymond J.R. 5-HT~1A~ receptor stimulate extracellular
signal-regulated protein kinase via NAD(P)H oxidase and reactive oxygen
species upstream of Src in CHO-K1 fibroblasts. Presented at the Miami
Nature Biotechnology Winter Symposia, Miami, FL, February 6-10 (1999);
*MNB Short Reports* **v.10**, 43 (1999).

35a. Mukhin Y.V., Collinsworth G.P., Fitzgibbon, W., Ploth, D.W.,
Raymond J.R. **Garnovskaya M.N.** Bradykinin B~2~ receptor activation
increase Na^+^/H^+^ exchange in mIMCD-3 cells. Presented at the Annual
FASEB Meeting, Washington, DC, *FASEB J.* **13**:A135, (1999).

36a. **Garnovskaya M.N.**, Mukhin Y.V., Raymond J.R. Angiotensin II and
serotonin induce the phosphorylation of serine 727 of STAT3 in vascular
smooth muscle cells. Presented at the Annual FASEB Meeting, Washington,
DC, *FASEB J.* **13**:A468, (1999).

37a. Mukhin Y.V., Bell J., Collinsworth G.P., Raymond J.R., Ploth, D.W.,
**Garnovskaya M.N.** Bradykinin B~2~ receptor activation induces
multiple cellular responses in M-1 cortical collecting duct cells.
Presented at the International Nephrology Meeting, Buenos Aires,
Argentina (May 1999).

38a. Raymond J.R., Mukhin Y.V., Reilly C., Collinsworth G.P., and
**Garnovskaya M.N.** Use of the Cytosensor and FLIPR to probe methabolic
pathways. Presented at the Third International Cell Analysis Products
Users Meeting, Monterey, CA., (1999).

39a. Mukhin Y.V., Bell J., Collinsworth G.P., Raymond J.R., Ploth, D.W.,
and **Garnovskaya M.N.** The use of FLIPR and Cytosensor to study
bradykinin-induced cellular responses in M-1 cortical collecting duct
cells. Presented at the Third International Cell Analysis Products Users
Meeting, Monterey, CA., (1999).

40a. **Garnovskaya M.N.**, Mukhin Y.V., Collinsworth G.P., Fitzgibbon,
W., Raymond J.R., and Ploth, D.W. Characterization of bradykinin B~2~
receptors in inner medullary collecting duct cells with FLIPR and
Cytosensor^TM^ microphysiometer. Presented at the Third International
Cell Analysis Products Users Meeting, Monterey, CA., (1999).

41a. Chen R., Paul R.V., **Garnovskaya M.N.**, Mukhin Y.V., Raymond
J.R., and Ullian M.E. A functional angiotensin type 1 receptor-GFP
fusion protein. Presented at the 53^rd^ Annual Fall Conference and
Scientific Sessions of the Council for High Blood Pressure Reaserch,
September 13-16, (1999).

42a. Andy J., Grewal J., Greene E., **Garnovskaya M.N.**, Mukhin Y.V.,
Collinsworth G.P., and Raymond J.R. Indoxyl Sulfate stimulates
phosphorylation of ERK in cultured rat mesangial cells. Presented at the
32^nd^ Annual Meeting of the American Society of Nephrology, November
5-8 (1999).

43a. Mukhin Y, **Garnovskaya M**, Collinsworth G. Fitzgibbon W, Raymond
J, Ploth D. Bradykinin Stimulates a Complex Formation between Calmodulin
and Janus Kinase in mIMCD-3 Cells. Presented at the Annual FASEB
Meeting, San Diego, CA; *FASEB Journal*; **14**:A589 (442.16) (2000).

44a. **Garnovskaya M**, Mukhin Y, Collinsworth G, Ulian M, Raymond J.
The Role of the Na^+^/H^+^ Exchanger in the Mitogen-Induced Activation
of Extracellular Signal Regulated Protein Kinase in Vascular Smooth
Muscle Cells. Presented at the Annual FASEB Meeting, San Diego, CA;
*FASEB Journal*; **14**:A592 (442.29) (2000).

45a. Chen R, Mukhin Y.V., **Garnovskaya M.N.**, Raymond J.R., and Paul
R.V. Use of Rodamine-Angiotensin II Conjugate to Trace the Angiotensin
Receptor. Presented at the Annual FASEB Meeting, San Diego, CA; *FASEB
Journal*; **14**:A724 (499.18) (2000).

46a. Mukhin Y.V., Vlasova T.M., Grewal J.S., Ullian M.E., Tholanikunnel
B.G., Raymond J.R., and **Garnovskaya M.N.** ERK is an intermediate for
rapid phosphorylation of serine ^795^ of the retinoblastoma gene product
in vascular smooth muscle cells. Presented at the annual FASEB Meeting,
Orlando, FL (April 2001); *FASEB Journal* 2001 **15**: A205(193.10).

47a. Lefler D.M., Collinsworth G., Mukhin Y.V., **Garnovskaya M.N.**,
Raymond J.R. Jak2 and Calmodulin are critical mediators of bradykinin 2
receptor activation of Na^+^/H^+^ exchange in three cell lines.
Presented at the 2001 ASN/ISN World Congress of Nephrology, San
Francisco, CA (October 2001).

48a. Mukhin Y.V., Garnovsky E.A., Raymond J.R., and **Garnovskaya M.N.**
Bradykinin B2 receptor activates ERK in mIMCD3 cells via epidermal
growth factor transactivation. Presented at the annual FASEB Meeting,
New Orleans (April 2002); *FASEB Journal* 2002 **16**: A171(158.19).

49a. Mukhin Y.V., Garnovsky E.A., Raymond J.R., and **Garnovskaya M.N.**
Bradykinin B2 receptor activates ERK in mIMCD3 cells via epidermal
growth factor transactivation.Presented at the 16^th^ International
Conference KININ 2002, Charleston, SC (May 2002); MUSC: Program and
Abstracts, 2002; 63 (P-21).

50a. **Garnovskaya MN**, Mukhin YV, Raymond JR. The Mechanism of
Epidermal Growth Factor Receptor Transactivation by Bradykinin B~2~
Receptor in mIMCD-3 Cells. Presented at the 16^th^ International
Conference KININ 2002, Charleston, SC (May 2002); MUSC: Program and
Abstracts, 2002; 62 (P-20).

51a. **Garnovskaya MN**, Mukhin YV, Raymond JR. The Na^+^/H^+^ exchanger
regulates mitogen-activated protein kinase upstream of Ras in vascular
smooth muscle cells. Presented at the annual FASEB Meeting, San Diego,
CA (April 2003); *FASEB Journal* 2003 **17**: A1016 (635.20).

52a. Mukhin Y.V., Raymond J.R., and **Garnovskaya M.N.** Novel mechanism
of EGF receptor transactivation by bradykinin B~2~ receptor in kidney
cells. Presented at the annual FASEB Meeting, San Diego, CA (April
2003); *FASEB Journal* 2003 **17**: A1013 (635.04).

53a. Turner J.H., **Garnovskaya M.N.**, Mukhin YV, and Raymond JR.
Regulation of the type 1 Na^+^/H^+^ exchanger by Janus kinase and
Ca^2+^/calmodulin. To be presented at the annual FASEB Meeting, San
Diego, CA (April 2003); *FASEB Journal* 2003 **17**: A1029 (647.10).

54a. Gooz, M., Raymond JR, and **Garnovskaya MN**. Cross talk between
serotonin (5HT~2A~) and epidermal growth factor receptors (EGFR)
involves heparin-binding EGF-like growth factor (HB-EGF) and activation
of metalloproteinase-like enzyme(s) in rat mesangial cells. Presented at
World Congress of Nephrology 2003, Berlin, Germany (June 2003).

55a. **Garnovskaya MN**, Mukhin YV, Gooz, M., and Raymond JR. Matrix
metalloproteinases are involved in bradykinin B~2~ receptor-induced
epidermal growth factor receptor transactivation in kidney cells.
Presented at the HUPO 2^nd^ Annual & IUBMB XIX Joint World Congress,
Montreal, Canada (October 2003*)*; *Mol & Cell Proteomics* 2003
**2**,#9, p.910 (87.10).

56a. **Garnovskaya MN**, Mukhin YV, Gooz, M., and Raymond JR. Matrix
metalloproteinases 8 and 13 mediate epidermal growth factor receptor
transactivation by bradykinin B~2~ receptor in kidney cells. Presented
at 12^th^ International conference on second messengers and
phosphoproteins, Montreal, Canada (August, 2004); *Book of Abstracts*
2004, p.128 (THP037).

57a. Gooz, M., Raymond JR, and **Garnovskaya MN**. Cross-talk between
Gq-coupled 5HT2A and EGF receptor involves HB-EGF, ADAM17 and integrin
activation in human mesangial cells. Presented at 12^th^ International
conference on second messengers and phosphoproteins, Montreal, Canada
(August, 2004); *Book of Abstracts* 2004, p.129 (THP038).

58a. **Garnovskaya MN**, Gooz M, Mukhin YV, and Raymond JR. Bradykinin
B~2~ receptor-induced ERK activation in kidney cells involves integrins.
Presented at the annual FASEB Meeting, San Diego, CA (April 2005);
*FASEB Journal* 2005 **19**:A1548 (876.6).

59a. Mukhin YV, Raymond JR, Ploth DW, and **Garnovskaya MN**. Small
GTP-binding proteins differentially regulate bradykinin-induced H^+^
effluxes in mIMCD-3 and M-1 cells. Presented at the annual FASEB
Meeting, San Diego, CA (April 2005); *FASEB Journal* 2005 **19**:A521
(314.11).

60a. Scholz D, McDermott PJ, **Garnovskaya M**, Huettelmaier S,
Mimore-Kiyosue Y, Goetze B, Derienzo C, Cooper G. MAP-4 inhibits the
microtubule-dependent distribution of mRNA in cardiocytes. Presented at
the 9^th^ annual scientific meeting of the Heart Failure Society of
America Boca Raton, FL (September 2005); J of Cardiac Failure 2005
**11**; S103 (049).

61a. Scholz D, **Garnovskaya M**, Huettelmaier S, Goetze B, Kiebler M,
Mimore-Kiyosue Y, Cooper G. Microtubule-dependent distribution of
cardiocyte mRNA: Inhibition by MAP4 decoration of microtubules.
Presented at the AHA Scientific Sessions, Dallas TX (November 2005).

62a. Coaxum S, Gooz M, Baldys A, **Garnovskaya MN** and Raymond JR.
Epidermal growth factor activates Na^+^/H^+^ exchange in podocytes
through a mechanism that involves Janus kinase and calmodulin. Presented
at the annual FASEB Meeting, San Francisco, CA (April 2006); *FASEB
Journal* 2006 **20**:A764 (472.25).

63a. Marlene Bunni, Inga Kramarenko, Linda Walker, John R. Raymond, and
**Maria N Garnovskaya**. Role of Integrins in Angiotensin II-induced
Proliferation of Vascular Smooth Muscle Cells. Presented at the
Experimental Biology Meeting, San Diego, CA; April 2008 (822.8).

64a. Inga Kramarenko, Marlene Bunni, John R Raymond, and **Maria N
Garnovskaya**. Bradykinin B~2~ Receptor Interacts with Integrin α5/β1 to
Transactivate Epidermal Growth Factor Receptor in Kidney Cells.
Presented at the Experimental Biology Meeting, San Diego, CA; April 2008
(829.5).

65a. Inga Kramarenko, Marlene Bunni, John R Raymond, and **Maria N
Garnovskaya**. Bradykinin B~2~ Identification of a Functional Bradykinin
B~2~ Receptor Expressed in HEK293 Cells. Presented at the Experimental
Biology Meeting, San Diego, CA; April 2008 (LB305).

66a. **Maria N Garnovskaya**, Inga Kramarenko, Marlene Bunni, John R
Raymond, and Thomas A Morinelli. Bradykinin B~2~ Receptor Induces
Multiple Cellular Responses Leading to Proliferation of Renal Carcinoma
Cells. Presented at the Experimental Biology Meeting, San Diego, CA;
April 2008 (LB297).