Tdms web page

Toxicology Data Management Systems

Chemical Directory Quick Reference

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Toxicology data management systems

Chemical Directory Quick Reference

> Prepared for: National Institute of Environmental Health Sciences
>
> Research Triangle Park, NC 2779
>
> Contract no.: 273-95-I-0012
>
> Prepared by: Technology Planning & Management Corporation
>
> Imperial Center
>
> Canterbury Hall, Suite 310
>
> 4815 Emperor Boulevard
>
> Durham, NC 27703

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Table of Contents

**Introduction**

Home Page for TDMS

**Figure 2A** TDMS Home Page.

**Figure 2B** Adding A Bookmark for the TDMS Home Page

Understanding the Output

Report Format and Variables

**Figure 3A** Example of a Chemical Directories WWW Report

Finding Items of Interest

**Figure 3B** Finding Chemical Directories

**Figure 3C** "Find What" box

Printing

**Figure 3D** Printing Chemical Directories

**Figure 3E** Printer Destination

Appendix

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Introduction

All TDMS users should become familiar with the instructions in this
guide.

In this reference, readers will find instructions on how to retrieve
information from TDMS Chemical Directories, via the World Wide Web
(WWW).

Before using this guide, readers should be familiar with TDMS and
Netscape. For detailed information about the chemical directories, refer
to *Obtaining TDMS Reports from the NIEHS VAX Computers.* Your user
support liaison can help you to obtain documentation.

Chemical Directories via the Web are available by way of PC and
Macintosh workstations that meet the requirements listed in the chart
below. If you are assigned to an NIEHS project and question whether or
not your workstation is fitted with these terms, contact your computer
support person (CSP).

  ----------------------- ----------------------- -----------------------
                          **PC**                  **MAC**

  Hardware Requirements   486 Processor or        68040, Power PC or
                          greater; at least 8MB   greater; at least 8MB
                          RAM                     RAM

  Software Requirements   Netscape 2.0 or greater Netscape 2.0 or greater
  ----------------------- ----------------------- -----------------------

The first step toward generating a report from the Web is accessing the
TDMS Home Page. An explanation of how to get to the home page is offered
in ***Section 2***.

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Home Page for TDMS

Here we explain how to access the TDMS home page and link to the
Chemical Directories.

The home page for TDMS furnishes a link to the Chemical Directory.
Complete the following instructions to reach the home page:

+-----+----------------------------------------------------------------+
| S   | Procedure                                                      |
| tep |                                                                |
+-----+----------------------------------------------------------------+
| 1   | Open your Netscape Navigator                                   |
| .   |                                                                |
+-----+----------------------------------------------------------------+
| 2   | In the Location input box type, http://ntp-db.niehs.nih.gov/.  |
| .   | The document in ***Figure 2A*** should appear.                 |
+-----+----------------------------------------------------------------+
|     |                                                                |
+-----+----------------------------------------------------------------+

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**Figure 2A** TDMS Home Page.

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+-----+----------------------------------------------------------------+
| 3   | To facilitate access, it is a good idea to bookmark the WWW    |
| .   | pages you frequent. From the Bookmarks menu, choose **Add      |
|     | Bookmark.** Your browser will automatically name and store the |
|     | active document. The next time you want to access the          |
|     | document, select it from the Bookmarks menu. Refer to          |
|     | ***Figure 2B***.                                               |
+-----+----------------------------------------------------------------+

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**Figure 2B** Adding A Bookmark for the TDMS Home Page

  ------ ----------------------------------------------------------------
  4      At the home page, you are prompted to select one of the
         available link options. Make a selection by clicking your mouse
         on one of the highlighted options (shown in ***Figure 2C***).

  ------ ----------------------------------------------------------------

On the Toxicology Data Management System web page, you may choose from
four options:

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**TDMS Inlife and Pathology Reports**

See the *TDMS Web Reports Quick Reference* guide when choosing this
option.

**TDMS Chemical Directory for All Studies**

Displays a list of all chemicals studied from 1981 to the current
period; sorted alphabetically by chemical name.

**Active Studies by Chemical**

Displays a list of all active studies currently active; sorted
alphabetically by chemical name.

**Active Studies by Lab**

Displays a list of all studies currently active; sorted alphabetically
by laboratory code.

***Section 3*** describes the information found in the directories and
offers tips on how to find specific items of interest.

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Understanding the Output

This section describes the information returned by the TDMS Chemical
Directories..

What follows is a general overview provided for readers that aren't
experienced in reading Chemical Directory reports.

Chemical Directory reports from the Web appear similar to those output
directly from the operating system at NIEHS. Thus, readers who have
experience reading TDMS reports may not require this overview.

# Report Format and Variables

All of the reports from the Chemical Directory component of TDMS are
formatted similarly and have the same variables. Reports are segmented
into four sections. The four sections are shown in ***Figure 3A*** and
summarized as follows.

**Report Title**

Provides the date on which the data for your report was last updated.
Regardless of which report is requested, all reports have the same
name--- *Chemical Directory of NTP Studies.*

**Chemical Name or Laboratory Name**

A header that introduces the succeeding segment of information; depends
on the type of report requested. As an example, assume that you have
requested Active Studies Only, Sorted by Lab. In this example, the
Sorted By header will be a lab code (BC, for instance) that leads into
the data recorded for that lab.

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**General Test Information**

Lists general and administrative information about a study. Includes...

-   Test type

-   Route

-   Species tested

-   Date on which animals received first dose

-   TDMS, CAS, and NTP numbers

-   Code for laboratory performing (or that performed) the test

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height="3.8131944444444446in"}

**Figure 3A** Example of a Chemical Directories WWW Report

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**Designation of Treatment Groups**

The Designation of Treatment Groups section of the Chemical Directories
WWW Reports lists general and administrative information about the
treatment groups used in a study. It includes the following:

-   Dosage applied to each group

-   Role (see the ***Appendix*** for codes)

-   Sex

-   Vehicle(s)

Note

> With respect to the variable, vehicle: When no vehicle is (was) used
> for a treatment group, the comment No Vehicle Assigned is displayed.
> When the vehicle does not change among treatment groups, the vehicle
> is listed only once. Subsequent vehicles are the same as the last
> vehicle commented.

# Finding Items of Interest

Chemical Directory reports are extensive. And yet, you may only require
a fraction of the data returned. You may search the report to find more
specific information.

Using the Find command, you can perform keyword searches for chemical
names, laboratory codes, study numbers, and any other data in a report.
There are a couple of ways to start the search function in a WWW
document. Each are listed below:

-   From the Edit menu, choose Find in Page (see ***Figure 3B***)

-   *or* Press [ctrl + f]{.smallcaps}

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**Figure 3B** Finding Chemical Directories

Either action displays the Find input box, shown in ***Figure 3C*** on
the next page. To execute a search, complete the instructions that
follow.

+-----+----------------------------------------------------------------+
| S   | Procedure                                                      |
| tep |                                                                |
+-----+----------------------------------------------------------------+
| 1   | In the Find What input box, type a keyword. Choose Find Next   |
| .   | to submit the command. The search function moves the cursor to |
|     | the first instance of the keyword.                             |
+-----+----------------------------------------------------------------+
| 2   | Click on the Cancel button to exit the modal dialog.           |
| .   |                                                                |
+-----+----------------------------------------------------------------+
| 3   | To find subsequent instances of your keyword, press            |
| .   | [f3]{.smallcaps}.                                              |
+-----+----------------------------------------------------------------+

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height="1.3333333333333333in"}

**Figure 3C** "Find What" box

# Printing

Chemical Directory reports can be printed in their entirety by selecting
**Print** from the File menu (see ***Figure 3D***). On selection, the
Print dialog box appears. Make certain that your choice printer is
denoted in the Name input box, before choosing OK. (Refer to ***Figure
3E***.)

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**Figure 3D** Printing Chemical Directories

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**Figure 3E** Printer Destination

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Appendix

The Treatment Role Table

  ------------- ---------------------------------------------------------
  Code          Description

  I             Initiator Control

  n             Negative Control

  p             Positive Control

  r             Promoter Control

  s             Sentinel

  t             Treated

  u             Untreated Control

  v             Vehicle Control

  x             Special Control
  ------------- ---------------------------------------------------------

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