Number range CHAPTERMarch 2007

[CURRICULUM VITAE]{.underline}

[Name]{.underline}: Francis W. Ruscetti

[Date & Place of Birth]{.underline}: February 6, 1943; Boston, MA

[Citizenship]{.underline}: United States

[Marital Status]{.underline}: Married; one child

[Education]{.underline}:

1968 B.S. (Biology), Boston University, Boston, MA

1972 Ph.D (Microbiology), University of Pittsburgh, Pittsburgh, PA

[Brief Chronology of Employment]{.underline}:

1972-1975 Research Instructor, Department of Medicine

University of Pittsburgh, School of Medicine

Pittsburgh, PA

1975-1978 Cell Biologist, Department of Cell Biology,

Litton Bionetics, Inc., Kensington, MD

1978-1983 Cancer Expert, Laboratory of Tumor Cell Biology

National Cancer Institute

Bethesda, MD

1983-1984 Cancer Expert, Laboratory of Molecular Immunoregulation

Biological Response Modifiers Program

National Cancer Institute

Frederick, MD

1984-1992 Senior Investigator, Head, Lymphokine Section

Laboratory of Molecular Immunoregulation

Biological Response Modifiers Program

National Cancer Institute

Frederick, MD

1992-2002 Chief, Laboratory of Leukocyte Biology

Division of Basic Sciences

National Cancer Institute - Frederick Cancer Research

& Development Center

Frederick, MD

2002-2004 Principal Investigator, Leukocyte Biology Section

Basic Research Laboratory

National Cancer Institute - Frederick

Frederick, MD

2004 - Date Principal Investigator, Leukocyte Biology Section

Laboratory of Experimental Immunology

Center for Cancer Research

National Cancer Institute - Frederick

[Military Service]{.underline}:

1964-1968 United States Air Force

[Societies]{.underline}:

American Society for Microbiology

> International Association for Comparative Research on Leukemia and
> Related Diseases

International Society for Experimental Hematology

American Society of Hematology

American Association for Immunologists

[Honors & Other Special Scientific Recognition]{.underline}:

Andrew Mellow Fellowship, 1969-1972

NIAMDD Consultant in Hematology Research, 1979-1981

Member, Cell Proliferation Committee of Amer. Soc. of Hematology,
1983-1986

Editorial Board, Experimental Hematology, 1986-1988

Adjunct Professor of Biochemistry and Molecular Biology, George
Washington University, 1988-Date

HHS Distinguished Service Award for Biomedical Research, 1991

Scientific Advisory Board, Guthrie Institute for Medical Research,
1991-2003

Editorial Board, Experimental Hematology, 1994-1996

Editorial Board, J. of Interferon & Cytokine Res., 1994-2000

Editorial Board, Stem Cells, 1994-Present

Award for Contribution to Human Retrovirology, Human Retrovirology
Society, 2005

[Research Interests]{.underline}:

> Regulation of growth and differentiation of human leukocytes; biology
> and etiology of human leukemia; interactions of regulatory factors,
> chemicals, and oncogenic viruses with hematopoietic cells; tumor and
> viral mediated immunosuppression.

[Present Address]{.underline}: 6933 Meadow Lake Road

New Market, MD 21774

[BIBLIOGRAPHY]{.underline}

1\. Ruscetti, F.W. and Jacobson, L.A.: Accumulation of 70S monoribosome
in [Escherichia coli]{.underline} after energy source shift-down. [J.
Bact]{.underline}. 111: 142-151, 1972.

2\. Chervenick, P.A., Ruscetti, F.W., and LoBuglio, A.F.:
Monocyte-macrophage stimulation of granulocytic and mononuclear colonies
in vitro. In: [Second International Workshop on Hematopoiesis in
Culture]{.underline} (DHEW) Publ. No. 73-804, Robinson, W. A. (Ed),
1973, pp. 117-126.

3\. Ruscetti, F.W. and Chervenick, P.A.: Release of colony-stimulating
factor from monocytes by endotoxin and polyino-sinic-polycytidylic acid.
[J. Lab. Clin. Med.]{.underline} 83: 64-72, 1974.

4\. Ruscetti, F.W. and Chervenick, P.A.: The release of
colony-stimulating activity from thymus-derived lymphocytes. [J. Clin.
Invest.]{.underline} 55: 520-527, 1975.

5\. Ruscetti, F.W. and Chervenick, P.A.: Regulation of the release of
colony- stimulating activity from mitogen stimulated lymphocytes. [J.
Immunol.]{.underline} 114: 1513-1517, 1975.

6\. Ruscetti, F., Cypress, R., and Chervenick, P.: Specific release of
neutrophil and eosinophil stimulating factors from sensitized
lymphocytes. [Blood]{.underline} 47: 757-765, 1976.

7\. Ruscetti, F.W., Boggs, D.R., Torok, B.J., and Boggs, S.S.: Reduced
blood and marrow neutrophils and granulocyte colony-forming cells in
S1/S1^d^ mice. [Proc. Soc. Exp. Biol. Med.]{.underline} 152: 398-402,
1976.

8\. Morgan, D.A., Ruscetti, F.W., and Gallo, R.C.: Growth of
thymus-derived lymphocytes from normal human bone marrow.
[Science]{.underline} 193: 1007-1008, 1976.

9\. Wu, A., Ruscetti, F., and Gallo, R.: Cell-factor inter-actions in
populations of normal and leukemic blood cells. In: [Experimental
Hematology Today]{.underline}, Baum, S. and Ledney, G. (Eds),
Springer-Verlag, New York, 1977, pp. 165-176.

10\. Gallo, R., Saxinger, W., Gallagher, R., Gillespie, D., Aulakh, G.,
Wong-Staal, F., Ruscetti, F., and Reitz, M.: Some ideas on the origin of
human leukemia in man and recent evidence for the presence of type-C
viral related information. In: [Origins of Human Cancer]{.underline},
Watson, J.D. and Hiatt, H. (Eds), Cold Spring Harbor Press, Cold Spring
Harbor, New York, 1977, pp. 1253-1265.

11\. Ruscetti, F.W., Morgan, D.A., and Gallo, R.C.: Functional and
morphological characteristics of human thymus-derived lymphocytes
continuously growing *in vitro*. [J. Immunol.]{.underline} 119: 131-138,
1977.

12\. Ruscetti, F.W., Allulunis, J., and Chervenick, P.A.: Mechanism of
release of colony stimulating activity from
mitogen-stimulatedlymphocytes: Effect of cytochalasin B. [Cell.
Immunol.]{.underline} 36: 3348-3392, 1978.

13\. Gallagher, R., Ruscetti, F., Collins, S., and Gallo, R.: Growth and
differentiation of human myelogenous leukemia cells in conditioned
medium from human embryo cultured cells. In: [Advances in Comparative
Leukemia Research]{.underline}, P. Benjvelzen and J. Hilgers (Eds),
Elsevier Press, Amsterdam, 1977, pp. 303-306.

14\. Gallo, R., Gallagher, R., and Ruscetti, F.: Human hematopoietic
cells: A search for retrovirus-related information in primary tissues of
leukemic cells and development of liquid suspension culture systems for
the study of cell growth and differentiation and viral-cell
interactions. In: [Differentiation of Normal and Neoplastic
Hematopoietic Cells]{.underline}, Marks, P., Clarkson, B., and Watson
J.(Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New
York, 1978, pp. 671-694.

15\. Gallo, R., Gallagher, R., Wong-Staal, F., Aoki, T., Markham, P.,
Schetters, H., Ruscetti, F., Varerio, M., O\'Keefe, R., Saxinger, W.,
Smith, R., Gillespie, D., and Reitz, M.: Isolation and tissue
distribution of type-C virus and viral components from a gibbon ape
([Hylobates]{.underline} [lar]{.underline}) with lymphocytic leukemia.
[Virol.]{.underline} 84: 359-373, 1978.

16\. Gillis, S., Baker, P., Ruscetti, F., and Smith, K.: Long-term
culture of human antigen specific cytotoxic T-cell lines. [J. Exp.
Med.]{.underline} 148: 1093-1098, 1978.

17\. Gallo, R., Ruscetti, F., Collins, S., and Gallagher, R.: Human
myeloid leukemia cells: Studies on oncornaviral related information and
in vitro growth and differentiation. In: [Hematopoietic Cell
Differentiation]{.underline}, Golde, D., Cline, M., Metcalf, D. and Fox,
C. (Eds), ICN-UCLA Symposium on Molecular and Cellular Biology, Vol. X.
Academic Press, New York, 1978, pp. 335-353.

18\. Gallo, R., Reitz, M. Saxinger, W., Jacquemin, P., and Ruscetti, F.:
Studies in human hematopoietic cells: Cellular and viral aspects. In:
[Antiviral Mechanisms forthe Control of Neoplasia]{.underline}, Chandra,
P. (Ed), Plenum Publishing Co., New York, 1978, pp. 153-175.

19\. Collins, S., Ruscetti, F., Gallagher, R., and Gallo, R.: Terminal
differentiation of human promyelocytic leukemia cells induced by
dimethyl sulfoxide and other polar compounds. [Proc. Natl. Acad.
Sci.]{.underline} 75: 2458-2462, 1978.

20\. Metzgar, R., Bertoglio, J., Bonnard, G., and Ruscetti, F.:
Detection of HLA-dRw (Ia-like) antigens on human T-lymphocytes grown in
tissue culture. [J. Immunol.]{.underline} 122: 949-953, 1979.

21\. Markham, P., Ruscetti F., Salahuddin, S., Gallagher, R., and Gallo,
R.: Enhanced induction of growth of B-lymphocytes from fresh human blood
by primate type-C retroviruses. [Int. J. Cancer]{.underline} 23:
148-156, 1979.

22\. Collins, S. J., Ruscetti, F. W., Gallagher, R. E., and Gallo, R.
C.: Normal functional characteristics of culture human promyelocytic
leukemia cells (HL-60) after induction of differentiation by
dimethyl-sulfoxide. [J. Exp. Med.]{.underline} 149: 969-976, 1979.

23\. Gallagher, R., Collins, S., Trujillo, J., McCredie, K., Ahearn, M.,
Tsai, S., Metzgar, R., Aulakh, G., Ting, R., Ruscetti, F., and Gallo, R.
C.: Characterization of the continuous, differentiating myeloid cell
line (HL-60) from a patient with acute promyelocytic-leukemia.
[Blood]{.underline} 54: 713-733, 1979.

24\. Smith, K., Gillis, S., Baker, P., McKenzie, D., and Ruscetti, F.:
T-cell growth factor mediated T-cell proliferation. [Ann. NY Acad.
Sci.]{.underline} 332: 423-428, 1979.

25\. Ruscetti, F., Collins, S., Gallagher, R., and Gallo, R.: Normal
functional characteristics of cultured human promyelocytic leukemia
cells. In: [Adv. in Comparative Leukemia Res.]{.underline}, Yohn, D.,
Lapin, B. and Blakeslee, W. (Eds), Elsevier Holland, Amsterdam, 1979,
pp. 13-15.

26\. Gallo, R., Wong-Staal, F., Markham, P., Ruscetti, F., Kalyanaraman,
V., Ceccharini-Nelli, L., Dalla-Favera, R., Joseph, S., Miller, N., and
Reitz, M.: Recent studies with infectious primate retroviruses:
Hybridization to primate DNA and some biological effects on fresh human
blood leucocytes by simian sarcoma virus and Gibbon ape leukemia virus.
In: [Viruses in Naturally Occuring Cancers]{.underline}, Essex, M.,
Todaro, G., and zur Hansen, H. (Eds), Cold Spring Harbor Laboratories,
New York, 1980, pp. 753-773.

27\. Boggs, D., Boggs S., and Ruscetti, F.: The W/Wv mouse as a model
system for the study of aplastic anemia. In: [Aplastic Anemia: A Stem
Cell Disease]{.underline}, Finch, C. and Levine, A. (Eds), (NHLBI) Publ.
#79-781, 1980, pp. 323-326.

28\. Smith, K.A., Baker, P.E., Gillis, S., and Ruscetti, F.W.:
Functional and molecular characteristics of T-cell growth factor. [Mol.
Immunol.]{.underline} 17: 579-589, 1980.

29\. Gallo, R. and Ruscetti, F.: New human hematopoietic cell systems
for the study of growth, differentiation and involved factors: Some
therapeutic implications. In: [Molecular Actions and Targets for Cancer
Chemotherapeutic agents]{.underline}, Lazo, J., Bertino, J. and
Sartorelli, J.(Eds), Academic Press, New York, 198l, pp. 555-577.

30\. Bradley, E.C. and Ruscetti, F.W.: The effect of interferons on
human tumor colony formation *in vitro*. [Cancer Res.]{.underline} 41:
244-249, 1980.

31\. Poiesz, B.J., Ruscetti, F.W., Mier, J.W., Woods, A.M., and Gallo,
R.C.: T-cell lines established from human T-lymphocytic neoplasias by
direct response to T-cell growth factor. [Proc. Natl. Acad. Sci.
USA]{.underline} 77: 6815-6819, 1980.

32\. Poiesz, B., Ruscetti, F., Gazdar, A., Bunn, P, Minna, J., and
Gallo, R.: Isolation of type-C retrovirus particles from cultured and
fresh lymphocytes from a patient with cutaneous T-cell lymphoma. [Proc.
Natl. Acad. Sci. USA]{.underline} 77: 7415-7419, 1980.

33\. Ruscetti, F.W. and Gallo, R.C.: Human T-lymphocyte growth factor:
Regulation of growth and function of T-lymphocytes. [Blood]{.underline}
57: 379-394, 1980.

34\. Ruscetti, F.W., Mier, J.W., and Gallo, R.C.: Human T-cell growth
factor: Parameters for production. [J. Supramol. Str.]{.underline} 13:
229-241, 1980.

35\. Ruscetti, F.W. and Gallo, R.C.: Production of T-cell growth factor
by cultured human T-lymphocytes. [Behring Inst. Res.
Commun.]{.underline} 67: 240-244, 1980.

36\. Reitz, M.S., Poiesz, B.J., Ruscetti, F.W., and Gallo, R.C.:
Characterization and distribution of nucleic acid sequences of a novel
type-C retrovirus isolated from neoplastic T-lymphocytes. [Proc. Natl.
Acad. Sci. USA]{.underline} 78: 1883-1887, 1981.

37\. Gallo, R., Poiesz, B., and Ruscetti, F.: Regulation of human T-cell
proliferation: T-cell growth factor and isolation of a new class of
type-C retrovirus from T-cells. In: [Modern Trends in Human
Leukemia]{.underline}, Neth, R., Gallo, R. Graf, T., Mannweiler, K., and
Winkler, K. (Eds), Springer-Verlag, Vol. IV, Berlin, 1981, pp. 502-514,
1981.

38\. Reitz, M., Poiesz, B., Ruscetti, F., and Gallo, R.C.:
Characterization by nucleic acid hybridization of HTLV, a novel
retrovirus, from neoplastic T-lymphocytes. In: [Modern Trends in Human
Leukemia]{.underline}, Neth, R., Gallo, R., Graf, T., Mannweiler, K.,
and Winkler, K. (Eds), Springer-Verlag, Berlin, Vol IV, 1981, pp.
515-517.

39\. Kalyanaraman, V.S., Sarngadharan, M.G., Poiesz, B.J., Ruscetti,
F.W., and Gallo, R.C.: Immunological properties of a type-C retrovirus
isolated from cultured human T-lymphoma cells and comparison to other
mammalian retroviruses. [J. Virol.]{.underline} 38: 906-915, 1981.

40\. Rho, H.M., Poiesz, B.J., Ruscetti, F.W., and Gallo, R.C.:
Characterization of the reverse transcriptase of a new retrovirus (HTLV)
produced by a human cutaneous T-cell lymphoma cell line.
[Virol.]{.underline} 112: 355-360, 1981.

41\. Ruscetti, F.W., Collins, S.J., Woods, A.M., and Gallo, R.C.: Clonal
analysis of the response of human myeloid leukemia cell lines to colony
stimulating activity. [Blood]{.underline} 58: 285-291, 1981.

42\. Markham, P., Ruscetti, F., Kalanaraman, V., Ceccherini-Nelli, L.,
Miller, N., Reitz, M., Salahuddin, S., and Gallo, R.: Restricted
expression of retrovirus nucleic acids and proteins in primate type-C
virus (Gibbon age leukemia virus-Simmian sarcoma virus) initiated human
B-lymphoblast cultures. [Cancer Res.]{.underline} 41: 2738-2744, 1981.

43\. Rabin, H., Hopkins, R., Ruscetti, F., Neubauer, R., Brown, R., and
Kawakami, T.: Spontaneous release of a factor with T-cell growth factor
activity from a continuous line of primate tumor T-cells. [J.
Immunol.]{.underline} 127: 1852-1857, 1981.

44\. Gallo, R., Popovic, M., Ruscetti, F., Wainberg, M., Royston, I.,
Reitz, M., Broder, S. and Robert-Guroff, M.: Interaction of T-cell
growth factor and a new retrovirus (HTLV) with human T-cells. In:
[Differentiation and Function of Hematopoietic Cell
Surfaces]{.underline} (ICN-UCLA Symposium on Molecular and Cellular
Biology), Vol. XIV, Marchesi, V., Gallo, R., Majerus, P., and Fox, C.,
(Eds), Alan R. Liss, Inc., NY, 1981, pp. 231-245.

45\. Robert-Guroff, M., Ruscetti, F.W., Posner, L.E., Poiesz, B.J., and
Gallo, R.C.: A monoclonal antibody specific for the human T-cell
lymphoma (leukemia) virus p19. [J. Exp. Med.]{.underline} 154:
1957-1964, 1981.

46\. Gallo, R., Wong-Staal, F., and Ruscetti, F.: Viruses and adult
leukemia-lymphoma of man and relevant animal models. In: [Adult
Leukemia]{.underline}, C. Bloomfield (Ed), Gruen-Stratton, NY, 1982,
Vol. 1, pp. 1-41.

47\. Posner, L.E., Robert-Guroff, M., Kalyanamaran, V.S., Poiesz, B.J.,
Ruscetti, F.W., Bunn, P.A., Minna, J.D., and Gallo, R.C.: Natural
antibodies to the retrovirus HTLV in patients with cutaneous T-cell
lymphomas. [J. Exp. Med.]{.underline} 154: 333-346, 1981.

48\. Salahuddin, S.Z., Markham, P.D., Ruscetti, F.W., and Gallo, R.C.:
Long-term suspension cultures of human cord blood myeloid cells.
[Blood]{.underline} 58: 931-938, 1981.

49\. Rabin, H., Hopkins, R.F., Yuan, L., Neubauer, R., and Ruscetti,
F.W.: Studies on the growth of primate T-cell lines using a primate
T-cell growth factor. In: [Advances in Comparative Leukemia
Research]{.underline}, Yohn, D., Strickland, D., and Blakeslee, W.
(Eds), Elsevier North Holland, Amsterdam, 1981, pp. 141-144.

50\. Ruscetti, F.W., Gootenberg, J., and Gallo, R.C.: Establishment of
cell lines from mature human T-cell neoplasias: Role of T-cell growth
factor. In: [Advances in Comparative Leukemia Research]{.underline},
Yohn, D. and Blakeslee, J. (Eds), Elsevier, NY, 1982, pp. 143-144.

51\. Poiesz, B.J., Ruscetti, F.W., Reitz, M.S., Kalyanaraman, V.S., and
Gallo, R.C.: Isolation of a new type-C retrovirus (HTLV) in primary
uncultured cells of a patient with Sezary T-cell leukemia.
[Nature]{.underline} 294: 268-271, 1982.

52\. Gootenberg, J.E., Ruscetti, F.W., Mier, J.W., Gazdar, A., and
Gallo, R.C.: Human cutaneous T-cell lymphoma cell lines produce and
respond to T-cell growth factor. [J. Exp. Med.]{.underline} 154:
1403-1418, 1982.

53\. Ruscetti, F.W., Foiesz, B.J., Tarella, C., and Gallo, R.C.: T-cell
growth factor and the establishment of cell lines from human T-cell
neoplasias. In: [Progress in Cancer Research and Therapy]{.underline},
Moore, M. (Ed), Raven Press, NY, 1982, pp. 153-166.

54\. Gallo, R.C., Breitman, T.R., and Ruscetti, F.W.: Proliferation and
differentiation of human myeloid cell lines in vitro. In: [Progress in
Cancer Research and Therapy]{.underline}, Moore, M.A.S. (Ed), Raven
Press, NY, 1982, pp. 96-114.

55\. Gallo, R., Robert-Guroff, M., Kalyanaraman, V., Ceccherini-Nelli,
L., Ruscetti, F., Broder, S., Sarngadharan, M., Ito, Y., Maeda, M.,
Wainberg, M., and Reitz, M.: Human T-cell retrovirus and adult T-cell
leukemia and lymphoma: Possible factors on viral incidence. In:
[Biochemical and Biological Markers in Neoplastic
Transformation]{.underline}, Candra, S. (Ed), Plenum Press, NY, 1982,
pp. 191-205.

56\. Ruscetti, F.W., Chou, J.Y., and Gallo, R.C.: Human trophoblasts: A
cellular source of CSA production in placental tissue.
[Blood]{.underline} 59: 86-90, 1982.

57\. Tarella, C., Ferraro, D., Gallo, E., Pagliardi, G.L., and Ruscetti,
F.W.: Induction of differentiation of HL-60 cells by dimethylsulfoxide:
Evidence for a stochastic model not linked to the cell division cycle.
[Cancer Res.]{.underline} 42: 445-449, 1982.

58\. Smith, K.A. and Ruscetti, F.W.: T-cell growth factor and the
culture of cloned functional T-cells. [Adv. in Immunol.]{.underline} 31:
139-172, 1982.

59\. Tarella, C., Ruscetti, F.W., Poiesz, B.J., Woods, A.M., and Gallo,
R.C.: Factors which affect human hemopoiesis are produced by T-cell
growth factor dependent and independent cultured neoplastic T-cells.
[Blood]{.underline} 59: 1330-1337, 1982.

60\. Gallo, R., Popovic, M., Ruscetti, F., Kalyanaraman, V. S., Reitz,
M., Royston, I., Broder, S., and Robert-Guroff, M.: Effects of human
T-cell lymphoma-leukemia virus (HTLV) and T-cell growth factor on human
T-cells. In: [Expression of Differentiated Functions in Cancer
Cells]{.underline}, Rossi, G. and Revoltella, R. (Eds), Raven Press, NY,
1982, pp. 191-205.

61\. Ceccherini-Nelli, L., Dalla-Favera, R., Markham, P., Ruscetti, F.,
Wong-Staal, F., Gallo, R.C., and Reitz, M.: Restricted expression of
integrated primate type-C virus and proviral A in non-productively
infected human B-lymphoblasts. [Virology]{.underline} 117: 195-206,
1982.

62\. Ruscetti, F.W., Mier, J., Gootenberg, J., and Gallo, RC.: The
interaction of human T-cell growth factor with normal and neoplastic
T-cells. In: [Progress in Clinical and Biological Responses in
Cancer]{.underline}, Mihich, E. (Ed), Plenum Press, NY, 1982, pp.
121-168.

63\. Gootenberg, J.E., Ruscetti, F.W., and Gallo, R.C.: A biochemical
variant of T-cell growth factor from a human T-cell lymphoma cell line.
[J. Immunol.]{.underline} 129: 1499-1505, 1982.

64\. Eastment, C., Ruscetti, F., Denholm, E. Arnold, E. and T\'So, P.:
The presence of hematopoietic mixed colony-forming cells in long-term
suspension cultures of hamster bone marrow. [Blood]{.underline} 60:
495-502, 1982.

65\. Eastment, C.E. and Ruscetti, F.W.: An evaluation of erythyropoiesis
in long-term hamster bone marrow cultures: Absence of a need for an
adherent monolayer. [Blood]{.underline} 60: 999-1006, 1982.

66\. Gallo, R., Mann, D., Broder, S., Ruscetti, F.W., Maeda, M.,
Kalyanaraman, V., Robert-Guroff, M., and Reitz, M.: Human T-cell
leukemia-lymphoma virus (HTLV) is in T but not B lymphocytes from a
patient with cutaneous T-cell lymphoma. [Proc. Natl. Acad. Sci.
USA]{.underline} 79: 5680-5684, 1982.

67\. Ferrero, D., Tarella, C., Gallo, E., Ruscetti, F., and Breitman,
T.: Terminal differentiation of the human promyelocytic leukemia cell
line, HL-60, in the absence of cell proliferation. [Cancer
Res.]{.underline} 42: 4421-4426, 1982.

68\. Ruscetti, F.: Biology of Interleukin-2. In: [Surv. Immunol.
Res.]{.underline}, Vol. 3, Schwartz, L. (Ed), Karger, Basel,
Switzerland, 1982, pp 122-126.

69\. Ruscetti, F. and Smith, K.: Glucocorticoid hormone suppression of
T-cell growth factor dependent growth of leukemic T-cells. In: [Leukemia
Rev. Internatl]{.underline}., Rich, M. (Ed), Marcel Dekker, NY, 1983,
pp. 217-218.

70\. Ruscetti, F.W.: The role of T-cell growth factor in the development
of allergic reactivity. [Proc. New Engl. Soc. Allergy]{.underline} 4:
79-85, 1983.

71\. Leverand, C., Harrison, D., Ruscetti, F., and Nebert, D.: Bone
marrow toxicity induced by oral benzopyrene: Protection resides at the
level of the intestine and liver. [Toxicol. Appl.
Pharmacol.]{.underline} 20: 90-401, 1983.

72\. Bradley, E., Ruscetti, F., Steinberg, H., Paradise, C., and Blaine,
K.: Inhibition of differentiation and proliferation of
colony-stimulating factor-induced clonal growth of normal human marrow
cells in vitro by retinoic acid. [J. Natl. Cancer Inst.]{.underline} 71:
1189-1192, 1983.

73\. Gootenberg, J., Ruscetti, F., and Gallo, R.: A biochemical variant
of human T-cell growth factor produced by a cutaneous T-cell lymphoma
cell line. In: [Interleukins, Lymphokines and Cytokines]{.underline},
Cohen, S. and Oppenheim, J. (Eds), Academic Press, NY, 1983, pp. 3-10.

74\. Ruscetti, F.W., Robert-Guroff, M., Ceccherini-Nelli, L., Minowada,
J., and Gallo, R.C.: Persistent in vitro infection by human T-cell
leukemia-lymphoma (HTLV) of normal human T-lymphocytes from blood
relatives of patients with HTLV associated mature T-cell neoplasias.
[Int. J. Cancer]{.underline} 31: 171-180, 1983.

75\. Zamkoff, K.W., Poiesz, B.J., Ruscetti, F.W., Moore, J.L., Davey,
F.R., Planas, A.T., and Lamberson, H.: Functional diversity within the
suppressor phenotype as defined by monoclonal antibody in T-cell
prolymphocytic leukemia. [Am. J. Hematol]{.underline}. 16: 409-417,
1984.

76\. Eastment, C.E. and Ruscetti, F.W.: Evaluation of hematopoiesis in
long-term bone marrow culture: Comparison of species differences. In:
[Long-Term Bone Marrow Cultures]{.underline}, Greenberger, J. and
Wright, D. (Eds), Alan R. Liss, Inc., NY, 1984, pp. 97-118.

77\. Eastment, C. and Ruscetti, F.: Regulation of erythropoiesis in
long-term hamster marrow cultures: Role of bone marrow adherent cells.
[Blood]{.underline} 65: 736-743, 1985.

78\. Poiesz, B., Moore, J., Merl, S., Tomar, R., Zamkoff, K.W., Davey,
F., Planas, A., Ehrlich, G., Ruscetti, F., Han, T., Cabradilla, C., and
Comis, R.: Biology and epidemology of HTLV. In: Cancer Cells #3, [Human
T-Cell Leukemia Virus]{.underline}., Gallo, R. and Essex, M. (Eds), Cold
Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1984, pp.
237-245.

79\. Oppenheim, J., Ruscetti, F., and Steeg, P.: In Fundenberg, H.,
Stiles, D., Caldwell, J., Wells, J. (Eds.): Basic and Clinical
Immunology 5th Edition. [Interleukins and Interferons]{.underline}.
Lange Medical Pub., Los Altos, CA, 1984, pp. 89-103.

80\. Ruscetti, F.W.: T-cell colony formation: absolute requirement for
T-cell growth factor. [Natural Immunity Cell Growth Reg.]{.underline} 3:
102-112, 1984.

81\. Owens, G., Jen-Jacobson, L., Ruscetti, F., and Jacobson, L.:
Functional and chemical modification of initiation factor 2 during
translational control of protein synthesis in E. Coli*.* [J.
Bacteriol.]{.underline} 125: 451-458, 1985.

82\. Eastment, C.E. and Ruscetti, F.W.: The development of
factor-producing and factor-dependent clones from hamster long-term
marrow in suspension cultures. [Exp. Hematol]{.underline}. 13: 525-531,
1985.

83\. Reeves, W., Zamkoff, K.W., Poiesz, B.J., Paolozzi, F.P., Tomar,
R.H., Moore, J.L., and Ruscetti, F.W.: T-cell growth factor required for
optimal induction of T-cell growth factor expression in PHA stimulated
T-cells. [J. Biol. Response Modifiers]{.underline} 4: 83-85, 1985.

84\. Brown, R.L., Griffith, R. L., and Ruscetti, F.W.: Modulation of
interleukin 2 release from a primate lymphoid cell line in serum-free
and serum-containing media. [Cell Immunol.]{.underline} 92: 14-21, 1985.

85\. Foon, K., Rossio, J., Schroff, R., Wahl, S., Ruscetti, F., Abrams,
P., Rager, H., Pickeral, S., and Fidler, I.: Generation of stable human
T-cell hybridomas which constitutively produce interleukin 2 and
chemotactic factor. [Hybridoma]{.underline} 4: 211-222, 1985.

86\. Oh, S-K., Farrar, W., and Ruscetti, F.: Modulation of E-receptor
expression on activated T-cells. [Clin. Exp. Immunol.]{.underline} 38:
55-67, 1985.

87\. Farrar, W.L., Ruscetti, F.W., and Young, H.A.: 5-Azacytidine
treatment of a murine cytotoxic T-cell line alters gamma interferon gene
induction by interleukin-2. [J. Immunol.]{.underline} 135: 1551-1554,
1985.

88\. Hoffman, P., Festoff, B., Giron, L., Hollenbeck, L., Garruto, R.,
and Ruscetti, F.: Isolation of LAV/HTLV-III from a patient with
amytrophic lateral sclerosis. [New Eng. J. Med.]{.underline} 325: 324,
1985.

89\. Ruscetti, F.: 1985 year of the interleukin-2 receptor. In: [Surv.
Immunol. Res.]{.underline}, Schwartz, L. (Ed), Karger, Basel,
Switzerland, 1985, Vol. 4, pp. 106-111.

90\. Rossio, J.L., Ruscetti, F.W., and Farrar, W.: Calcium mobilization
by specific recombinant ligands in IL-2 and IL-3-dependent cell lines.
[Lymphokine Res.]{.underline} 5: 163-172, 1986.

91\. Ruscetti, F.W.: Immunopathology associated with human T-cell-tropic
retroviruses. [Surv. Syn. Pathol. Res.]{.underline} 4: 216-226, 1985.

92\. Thurman, G., Maluish, A., Rossio, J., Scholick, E., Onozaki, K.,
Talmadge, J., Procopio, A., Ortaldo, J., Ruscetti, F., Stevenson, H.,
Cannon, G., Iyar, S., and Herberman, R.: Comparative evaluation of
multiple lymphoid and recombinant human IL-2 preparations. [J. Biol.
Res. Mod.]{.underline} 5: 85-107, 1985.

93\. Farrar, W.L. and Ruscetti, F.W.: Association of protein kinase C
activation with IL-2 receptor expression. [J. Immunol.]{.underline}
136:1266-273, 1986.

94\. Farrar, W., Evans, S., Ruscetti, F., Bonvini, E., Young, H., and
Birchnell-Sparks, M. C.: Biochemical mechanism(s) of interleukin-2
regulation of lymphocyte growth. In: [Role of Leucocytes in Host
Defense]{.underline}, Oppenheim, J. and Jacobs, D. (Eds), Alan R. Liss,
Inc., NY, 1986, pp. 125-130.

95\. Ruscetti, F., Kalyanaraman, V., Overton, R., Mikovits, J.,
Stevenson, H., Stromberg, K., Herberman, R., Farrar, W., and Ortaldo,
J.: Analysis of effector mechanisms against HTLV-I and HTLV-III/LAV
infected lymphoid cells. [J. Immunol.]{.underline} 136: 3619-3624, 1986.

96\. Lee, J., Rebar, L., Young, P., Ruscetti, F., Hanna, N., and Poste,
G.: Identification and characterization of a human T-cell line-derived
lymphokine with Maf-like activity distinct from interferon-gamma. [J.
Immunol.]{.underline} 136: 1322-1328, 1986.

97\. Schlick, E. and Ruscetti, F.: In vivo induction of terminal
differentiation of malignant myelopoietic progenitor cells by
CSF-inducing biological response modifiers. [Blood]{.underline} 67:
980-987, 1986.

98\. Ruscetti, F.W., Farrar, W.L., Hill, J.M., and Pert, C.:
Visualization of the human helper T-lymphocyte related antigen (T4) in
primate brain: Implications for HTLV-III/LAV infection.
[Peptide]{.underline} 9: 97-104, 1986.

99\. Faltynek, C., Princler, G., Rossio, J., Ruscetti, F., Maluish, A.,
Abrams, P., and Foon, K.: Relationship of the clinical response and
binding of recombinant interferon alpha in patients with
lympho-proliferative diseases. [Blood]{.underline} 67: 1077-1082, 1986.

100\. Abe, H., Rossio, J. L., Ruscetti, F. W., Matsushima, K., and
Oppenheim, J. J.: Establishment of a human B-cell line that proliferates
in response to B-cell growth factor. [J. Immunol. Meth.]{.underline} 90:
111-123, 1986.

101\. Farrar, W. and Ruscetti, F.: Developments concerning the
biochemical and molecular basis of IL 2 mediated T-cell growth. In:
[Surv. Immunol. Res]{.underline}., Cruse, J. (Ed), Karger, Basel,
Switz., 1986, Vol. 5, pp. 3043-3047.

102\. Sparks, M., Farrar, W., Rennick, D., and Ruscetti, F.: Interleukin
3 regulates expression of IL-2 receptors on IL-3 dependent cells by
increased transcription of the IL-2 receptor gene. [Science]{.underline}
233: 455-458, 1986.

103\. Bettens, F., Schlick, E., Farrar, W., and Ruscetti, F.: 1,2,5
Dihydroxychole-calciferol-induced differentiation of myelomonocytic
leukemic cells unresponsive to colony-stimulating factors and phorbol
esters. [J. Cell. Physiol.]{.underline} 129: 295-302, 1986.

104\. Pert, C., Hill, J., Ruff, M., Berman, R., Robey, W., Arthur L.,
Ruscetti, F., and Farrar, W.: Octapeptides deduced from the neuropeptide
receptor-like pattern of antigen T4 in potently inhibit human
immunodeficiency viral envelope receptor binding and human T-cell
infectivity. [Proc. Natl. Acad. Sci. USA]{.underline} 83: 9254-9258,
1986.

105\. Ferrero, D., Pregno, P., Tarella, C., Ruscetti, F., Pileri, A.,
and Gallo, E.: Improved culture conditions for in vitro growth of acute
myeloid leukemia clonogenic cells. [Cancer Res.]{.underline} 47:
6413-6417, 1987.

106\. Yamada, S., Ruscetti, F., Overton, W.R., Herberman, R.,
Birchenall-Sparks, M. C., and Ortaldo, J.R.: Regulation of human large
granular lymphocyte and T-cell growth and function by recombinant
interleukin 2: Induction of interleukin 2 receptors and promotion of
growth of growth of cells with enhanced cytotoxicity. [J. Leucocyte
Biol.]{.underline} 41: 505-517, 1987.

107\. Holbrook, N.J., Guliano, A., and Ruscetti, F.W.: Cis-acting
transcriptional regulatory sequences in the Gibbon ape leukemia virus
(GALV) long terminal repeat. [Virology]{.underline} 157: 211-219, 1987.

108\. Starkebaum, G., Kalyanaraman, V., Kidd, P., Loughran, T., Kadin,
M., Singer, J., and Ruscetti, F.: Serum reactivity to human T-cell
leukemia virus type I in patients with large granular lymphocytic
leukemia. [Lancet]{.underline} 1: 596-598, 1987.

109\. Bonvini, E., Ruscetti, F., Ponzoni, M., Hoffman, T., and Farrar,
W.: Interleukin 2 rapidly stimulates synthesis and breakdown or
polyphosinositides in interleukin 2 dependent, murine T-cell lines. [J.
Biol. Chem.]{.underline} 262: 4160-4164, 1987.

110\. Faltynek, C., Princler, G., Ruscetti, F., and Birchenall-Sparks,
M.: Lectins modulate the internalization of recombinant interferon  and
the induction of 2\'5\'-Oligo (A) synthetase. [J. Biol.
Chem.]{.underline} 263: 7112-7117, 1988.

111\. Keller, J., Mantel, C., Sing, G., Ellingsworth, L., Ruscetti, S.,
and Ruscetti, F.: Transforming growth factor-beta selectively inhibits
early murine hematopoietic progenitor cells and the growth of IL-3
dependent myeloid leukemic cell lines. [J. Exp. Med.]{.underline} 168:
737-750, 1988.

112\. Young, H., Birchenall-Sparks, M., and Ruscetti, F.:
Characterization of interleukin 2 and phorbol myristate acetate
augmentation of transfected human  interferon genomic DNA. [J.
Interferon Res.]{.underline} 8: 527-538, 1988.

113\. Sing, G., Keller, J., Ellingsworth, L., and Ruscetti, F.:
Transforming growth factor-beta selectively inhibits normal and leukemic
human bone marrow cells in vitro. [Blood]{.underline} 72: 1504-1511,
1988.

114\. Loughran, T., Starkebaum, G., and Ruscetti, F.: Similar
rearrangements of T-cell receptor  gene in cell lines and uncultured
cells from patients with large granular leukemia. [Blood]{.underline}
72: 613-615, 1988.

115\. Brownell, E., Ruscetti, F., Smith, R.G., and Rice, N.: Expression
of c-rel mRNA in human lymphoid populations. [Oncogene]{.underline} 3:
93-98, 1988.

116\. Takacs, L., Ruscetti, F., Kovacs, E., Rocha, B., Brocke S.,
Diamantstein, T., and Mathieson, B.: Immature double negative (CD4^-^~,~
CD8^-^) rat thymocytes do not express IL-2 receptors. [J.
Immunol.]{.underline} 141: 3810-3818, 1988.

117\. Ruscetti, F., Sing. G., Ellingworth, L., Ruscetti, S., and Keller,
J.: Transforming growth factor-beta a selective growth inhibitor for
hematopoietic progenitor cells. In: [Monokines and Other
Cytokines]{.underline}, Oppenheim, J. (Ed), Alan R. Liss, Inc., NY,
1988, pp 307-312.

118\. Pert, C. B., Ruff, J., Ruscetti, F., Farrar, W., and Hill, J. M.:
HIV receptor in brain and deduced peptides that block viral infectivity.
In: [Psychological, Neuro-Psychariatric and Substance Abuse Aspects of
AIDS]{.underline}, Bridge, T.B., et al. (Eds), Raven Press, NY, 1988, pp
73-83.

119\. Ruscetti, F., Sing, G., Ellingsworth, L., and Keller, J.:
Transforming growth factor a negative regulator of normal and leukemic
hematopoietic progenitor cell growth. In: [Experimental Hematology
Today]{.underline}, Baum, S. J., Dicke, K. A., Lotzova, E., and Pluznik,
D. (Eds), Springer-Verlag, Berlin, 1988, pp. 119-124.

120\. Papsidero, L., Sheu, M., and Ruscetti, F.: Human immunodeficiency
virus type 1 neutralizing monoclonal antibodies which react with p17
core protein: Characterization and epitope mapping. [J.
Virol.]{.underline} 63: 267-272, 1989.

121\. Ruscetti, F. W. and Mikovits, J. A.: Differential regulation of
the two IL-2 binding proteins. In: [Year in Immunology -
1988]{.underline}, Cruise, J. and Lewis, R. (Eds), Basel, Karger, 1989,
pp. 38-45.

122\. Birchenall-Roberts, M., Engelmann, G.L., Keller, J.R., Lohrey, N.,
and Ruscetti, F.: Retroviral v-myc infection of primary fetal liver
cells: Transformation of monocytes in vivo. [Oncogene]{.underline} 4:
731-735, 1989.

123\. Talmadge, J. E., Schneider, M., Keller, J., Ruscetti, F., Longo,
D., Pennington, R., Bowersox, O., and Tribble, H.: Myelostimulatory
activity of recombinant human interleukin 2 in mice. [Blood]{.underline}
73: 1458-1467, 1989.

124\. Keller, J., Sing, G., Ellingsworth, L., and Ruscetti. F.:
Transforming growth factor-beta: Possible roles in the regulation of
normal and leukemic hematopoietic cell growth. [J. Cell.
Biochem.]{.underline} 39: 175-184, 1989.

125\. Sing, G., Keller, J., Ellingsworth, L., and Ruscetti, F.:
Transforming growth factor-beta synerzies with tumor necrosis factor and
interferon in inhibiting hematopoietic cell growth. [J. Cell.
Biochem.]{.underline} 39: 117-128, 1989.

126\. Goey, H., Keller, J., Back, T., Longo, D. L., Ruscetti, F., and
Wiltrout, R.: Inhibition of early hematopoietic progenitor cell
proliferation with in vivo locoregional administration of transforming
growth factor-beta. [J. Immunol.]{.underline} 143: 877-880, 1989.

127\. Ruscetti, F., Sing, G., Burke, P., Schlick, E., Ruscetti, S., and
Keller, J.: Biological response modifiers in the growth and
differentiation of myeloid leukemic cells. In: [Current Topics in
Microbiol & Immunol]{.underline}. Vol. 149, Shen-Ong, G., Potter, M.,
and Copeland, N. (Eds), Springer-Verlag, Berlin, 1989, pp 165-172.

128\. Ruscetti, S. and Ruscetti, F.: Apparent Epo-independence of
SFFV-infected erythroid cells is not due to Epo production or change in
Epo receptors. [Leukemia]{.underline} 3: 703-707, 1989.

129\. Steis, R., Clark, J., Longo, D.L., Smith, J., Miller, R.,
Ruscetti, F., Hursey, J., and Urba, W.: A phase 1b evaluation of human
granulocyte-macrophage colony-stimulating factor. In: [Cancer
Therapy]{.underline}, Bergeret, H. et al. (Eds), Springer-Verlag,
Berlin, 1989, pp 103-111.

130\. Ruscetti, F.W.: Interleukin-2. In: [Immunophysiology]{.underline},
Oppenheim, J. and Shevach, E. (Eds), Oxford Press, Oxford, 1989, pp
49-73.

131\. Rossio, J.L. and Ruscetti, F.W.: Immunomodulation of neoplasia by
interleukin-2. In Cruise, J. and Lewis, R. (Eds.): [Prog. Tumor.
Res.]{.underline} 32: 174-186, 1989.

132\. Keller, J.R., Ellingsworth, L.R., McNiece, I.K., Quesenberry,
P.J., Sing, G.K., and Ruscetti, F.W.: Transforming growth factor-beta
directly regulates primitive murine hematopoietic cell proliferation.
[Blood]{.underline} 75: 596-602, 1990.

133\. De Benedetti, F., Ruscetti, F., Ellingsworth, L., and Faltynek,
C.: Synergy between transforming growth factor-beta and tumor necrosis
factor- in the induction of monocytic differentiation of human leukemic
cell lines. [Blood]{.underline} 75: 626-632, 1990.

134\. Loughran, Jr., T.P., Aprile, J.A., Strakebaum, G., and Ruscetti,
F.W.: Cellular and molecular analyses of activation of leukemic large
granular lymphocytes by anti-CD3 monoclonal antibody.
[Blood]{.underline} 75: 936-940, 1990.

135\. Twardzik, D., Mikovits, J., Ranchalis, J., Purchio, A.,
Ellingsworth, L., and Ruscetti, F.:  Interferon induced activation of
latent transforming growth factor by human monocytes. In: [Transforming
Growth Factor βs: Chemistry, Biology and Therapeutics]{.underline},
Piez, K.A., and Sporn, M.B. (Eds). [Ann. NY Acad. Sci.]{.underline} 593:
237-248, 1990.

136\. Keller, J., Sing, G., Ellingsworth, L., Ruscetti, S., and
Ruscetti, F.: Two forms of transforming growth factor  (TGF-β1 and
TGF-β2) are equally potent selective growth inhibitors of early murine
hematopoiesis. In: [Transforming Growth Factor βs: Chemistry, Biology
and Therapeutics]{.underline}, Piez, K.A. and Sporn, M.B. (Eds). [Ann.
NY Acad. Sci.]{.underline} 593: 172-180, 1990.

137\. Falk, L., DeBenedetti, F., Faltynek, C., and Ruscetti, F.: Effect
of retinoic acid on TGF 1 receptor expression in HL-60 cells. In:
[Transforming Growth Factor βs: Chemistry, Biology and
Therapeutics]{.underline}, Piez, K. and Sporn, M. (Eds). [Ann. NY Acad.
Sci.]{.underline} 593: 310-312, 1990.

138\. Falk, L.A. and Ruscetti, F.W.: Differential TGF-beta1 receptor
expression on quiescent and activated murine macrophages. In: [Molecular
and Cellular Biology of Cytokines]{.underline}, Powanda, M., Oppenheim,
J., Kluger, M., and Dinarello, C. (Eds), Alan R. Liss, Inc, NY, 1990,
pp. 137-142.

139\. Oppenheim, J., Dubois, C., Ruscetti, F., and Keller, J.:
Regulation of production and receptor expression for Interleukin-1 and
tumor necrosis factor. In: [Cytokines and Lipocortins in Inflammation
and Differentiation]{.underline}, Powanda, M., Oppenheim, J., Kluger,
M., and Dinarello, C. (Eds), Alan R. Liss, NY, 1990, pp. 178-184.

140\. Sing, G.K. and Ruscetti, F.W.: Preferential suppression of
myelopoiesis in normal human bone marrow cells following in vitro
challenge with human cytomegalovirus. [Blood]{.underline} 75: 1965-1973,
1990.

141\. Keller, J. R., Ruscetti, S. K., and Ruscetti, F. W.: Introduction
of the v-abl oncogene induces monocytic differentiation of an IL- 3
dependent myeloid progenitor cell line. [Oncogene]{.underline} 5:
549-555, 1990.

142\. Steis, R., VanderMolen, L. Lawrence, J., Sing, G., Ruscetti, F.,
Smith, J., Urba, W., Clark, J., and Longo, D.: Erythrocytosis in Hairy
Cell Leukemia following treatment with interferon-α. [Brit. J.
Hematol.]{.underline} 75: 133-135, 1990.

143\. Mikovits, J. A., Raziuddin, Gonda, M., Ruta, M., Lohrey, N., Kung,
H-F., and Ruscetti, F.: Negative regulation of HIV replication in
monocytes: Distinctions between restricted and latent expression in
THP-1 cells. [J. Exp. Med.]{.underline} 171: 1705-1720, 1990.

144\. Dubois, C., Ruscetti, F., Palazynski, E., Falk, L., Oppenheim, J.,
and Keller, J.: Transforming growth factor-beta is a potent inhibitor of
interleukin 1 (IL-1) receptor expression: proposed mechanism of
inhibition of IL-1 action. [J. Exp. Med.]{.underline} 172: 737-744,
1990.

145\. Birchenall-Roberts, M., Ferrer, C., Falk, L., and Ruscetti, F.:
Inhibition of murine monocyte proliferation by a CSF-1 antisense
oligodeoxy-nucleotides: Evidence for autocrine regulation. [J.
Immunol.]{.underline} 145: 3290-3296, 1990.

146\. Sing, G., Ruscetti, F., Beckwith, M., Keller, J., Ellingsworth,
L., Urba, W., and Longo, D.L.: Growth inhibition of human lymphoma cell
lines: Induction of a TGF-beta-mediated autocrine negative loop by
phorbol myristate. [Growth and Cell Diff.]{.underline} 1: 549-557, 1990.

147\. Bristol, L., Ruscetti, F., Brody, D., and Durum, S.: Interleukin
1 induces expression of active TGF-beta in non-proliferating T-cells
via a post-transcriptional mechanism. [J. Immunol.]{.underline} 145:
4108-4114, 1990.

148\. Birchenall-Roberts, M., Ruscetti, F., Kasper, J., Lee, H-D.,
Friedman, R., Drew, A., Sporn, M., Roberts, A., and Kim, S-J.:
Transcriptional regulation of the TGF-beta-1 promoter by v-src gene
products is mediated through the AP-1 complex. [Mol. Cell.
Biol.]{.underline}, 10: 4978-4983, 1990.

149\. Latham, P., Lewis, A., Varesio, L., Pavalakis, G., Felber, B.,
Ruscetti, F., and Young, H.: The effect of cytokines on the expression
of human immuno-deficiency virus long terminal repeat in the human
promonocyte cell line, U937. [Cell. Immunol.]{.underline} 129: 513-518,
1990.

150\. Steis, R., VanderMolen, L., Longo, D.L., Clark, J., Smith, J.,
Kopp, W., Ruscetti, F., Creekmore, S., Elwood, L., Hursey, J., and Urba,
W.: Recombinant human granulocyte-macrophage colony-stimulating factor
in patients with advanced malignancy: a phase 1b trial. [J. Natl. Cancer
Inst.]{.underline} 82: 697-703, 1990.

151\. Futami, H., Jansen, R., Keller, J., McCormick, K., Longo, D.L.,
Oppenheim, J., Ruscetti, F., and Wiltrout, R.: Chemoprotective effects
of rh-IL-1 in normal and tumor-bearing mice: Protection from acute
toxicity, hematologic effects, development of late toxicity and enhanced
therapeutics. [J. Immunol.]{.underline} 145: 4121-4130, 1990.

152\. Ruscetti, F., Dubois, C., Falk, L., Jacobsen, S.E.W., Sing, G.,
Longo, D. L., Wiltrout, R., and Keller, J.: In vivo and in vitro effects
of TGF-beta on normal and leukemic hematopoiesis. In: [Proceedings of
the Meeting Clinical Applications of TGF-beta]{.underline}, Brock, G.
and Marsh, J. (Eds), Chichester Ciba Foundation Symposium, 1991, pp.
212-132.

153\. Jacobsen, S.E., Ruscetti, F., Dubois, C., and Keller, J.:
Transforming growth factor-beta modulates the expression of GM-CSF and
G-CSF receptors on murine hematopoietic progenitor cell lines.
[Blood]{.underline} 77: 1706-1716, 1991.

154\. De Benedetti, F., Falk, L., Ruscetti, F.W., Colburn, N.H.,
Faltynek, C.R., and Oppenheim, J.J.: Inhibition of PMA-induced
transformation of JB6 by transforming growth factor-beta: Synergy
between TGF-beta and retinoic acid. [Cancer Res.]{.underline} 51:
1158-1164, 1991.

155\. Falk, L., De Benedetti, F., Lohrey, N., Birchenall-Roberts, M.,
Ellingsworth, L., Faltynek, C., and Ruscetti, F.: Induction of TGF
beta-1 receptor expression and TGF-beta-1 protein production in retinoic
acid-treated HL-60 cells: Possible TGF-beta-1-mediated autocrine
production. [Blood]{.underline} 77: 1246-1255, 1991.

156\. Altiok, A., Bejarno, M., Ruscetti, F., Altiok, E., Klein, G., and
Klein, E.: Effects of transforming growth factor beta-1 and beta-2 on
the proliferation of burkitt and lymphoblastoid cell lines. [Growth
Factors]{.underline} 4: 117-128, 1991.

157\. Birchenall-Roberts, M., Falk, L., Kasper, J., Keller, J.,
Faltynek, C., and Ruscetti, F.: Differential modulation of TGF-beta-1
receptors in murine myeloid cell lines: Correlation with differential
growth inhibition by TGF-beta-1. [J. Biol. Chem.]{.underline} 266:
9617-9621, 1991.

158\. Ruscetti, F., Jacobsen, S.E.W., Birchenall-Roberts, M., Broxmeyer,
H., Engelmann, G., Dubois, C., and Keller, J.: Role of TGF-beta-1 in the
regulation of hematopoiesis. In: [Negative Regulators of
Hematopoiesis]{.underline}, Anagnostou, A., et al. (Eds), Ann. NY Acad.
Sci., 628: 31-44, 1991.

159\. Hestdal, K., Ruscetti, F., Jacobsen, S.E.W., Dubois, C. M., Kopp,
W., Longo, D.L., and Keller, J.: Characterization and regulation of 8C5
(GR-1) antigen expression on murine bone marrow cells. [J.
Immunol.]{.underline} 147: 22-28, 1991.

160\. Keller, J., Jacobsen, S.E.W., Sill, K., Ellingsworth, L., and
Ruscetti, F.: Stimulation of granulopoiesis by transforming growth
factor-beta: [Proc. Natl. Acad. Sci.]{.underline} 88: 7190-7194, 1991.

161\. Geller, R., Strobl, S., Bach, F., Ruscetti, F., Longo, D.L., and
Ochoa, A.C.: Generation of lymphokine activated killer activity in T
cells: Possible regulatory circuits. [J. Immunol.]{.underline} 146:
3280-3288, 1991.

162\. Ortaldo, J., Mason, A., O\'Shea, J., Smyth, M., Falk, L., Kennedy,
I., Longo, D.L., and Ruscetti, F.: Mechanisms of TGF- inhibition of
IL-2 dependent activation of CD3^-^ LGL functions: Regulation of IL-2R 
(p75) signal transduction. [J. Immunol.]{.underline} 146: 3791-3798,
1991.

163\. Oppenheim, J., Dubois, C., Neta, R., Keller, J., Falk, L., and
Ruscetti, F.: Suppressive effects of transforming growth factor-beta on
the expression of interleukin 1 receptors (IL-1R). In: [Japanese Society
of Reproductive Immunology]{.underline}, Hojo, K. and Kasakura, S.
(Eds), 1991, pp. 33-38.

164\. Migdalska, A., Molineux, G., Demuynck, H., Evans, G. S., Ruscetti,
F., and Dexter, M.: Growth inhibitory effects of transforming growth
factor-beta-1 *in vivo*. [Growth Factors]{.underline} 4: 239-245, 1991.

165\. Jacobsen, S.E.W., Ruscetti, F.W., Longo, D.L., and Keller, J.R.:
The antineoplastic dolastatins are potent inhibitors of hematopoietic
progenitor cells. [J. Natl. Cancer Inst.]{.underline} 83: 1672-1677.

166\. Starkebaum, G., Loughran, T.P., Jr., Waters, C., and Ruscetti,
F.W.: Establishment of an IL 2-independent, human T-cell line possessing
only the  chain of the IL-2 receptor. [Int'l. J. Cancer]{.underline}
49: 246-253, 1991.

167\. Raziuddin, Mikovits, J., Clavert, I., Ghosh, S., Kung H-F., and
Ruscetti, F.: Negative regulation of HIV-1 expression in monocytes: Role
of the 65+50 kD NF κB heterodimer. [Proc. Natl. Acad. Sci.]{.underline}
88: 9426-9430, 1991.

168\. Jansen, R., Damia, G., Keller, J., Futami, H., Goey, H., Back, T.,
Longo, D.L., Ruscetti, F., and Wiltrout R.: Effect of recombinant
transforming growth factor-beta-1 (rTGF-beta-1) on hematopoietic
recovery following treatment of mice with 5-fluorouracil. [J.
Immunol.]{.underline} 147: 3342-3347, 1991.

169\. Dubois, C., Ruscetti, F., Keller, J., Oppenheim, J., Hestdal, K.,
Chizzonite, R., and Neta, R.: In vivo IL-1 administration indirectly
promotes Type II IL-1 receptor expression on hematopoietic progenitor
cells: Novel mechanism for the hematopoietic effects of IL-1.
[Blood]{.underline} 78: 2841-2848, 1991.

170\. Jacobsen, S.E.W., Keller, J., Ruscetti, F., Roberts, A., and Falk,
L.: Bidirectional effects of TGF-beta on CSF-stimulated human
myelopoesis: Differential effects of TGF-beta isoforms.
[Blood]{.underline} 78: 2239-2247, 1991.

171\. Broxmeyer, H.E., Sherry, B., Cooper, S., Ruscetti, F.W., Williams,
D.E., Arosio, P., Kwon, B.S., and Cerami, T.: Influence of recombinant
murine macrophage inhibitory proteins (MIP)-beta-1 on myeloid
progenitor cell suppression by MIP-beta-1 and comparison with H-ferritin
inhibitory activity. [J. Immunol.]{.underline} 147: 2586-2594, 1991.

172\. Baylor, N.W., Fu, T., Yan, Y-D, and Ruscetti, F.W.: In vitro
inhibition of human T-cell leukemia virus (HTLV-I) replication by
baicalin, a purified flavonoid compound. [J. Inf. Dis.]{.underline} 165:
433-437, 1992

173\. Johnston, P., Connaughton, G., Sullivan, F., Ruscetti, F., and
Longo, D.: Transient reversal of bone marrow aplasia associated with
lymphocyte depleted Hodgkin\'s disease after combination chemotherapy.
[Amer. J. Hematol.]{.underline} 38: 54-60, 1991.

174\. Keller, J.R. and Ruscetti, F.W.: Transforming growth factor beta
(TGF-beta) and its role in hematopoiesis. [Intl. J. Cell
Cloning]{.underline} 10: 2-11, 1992

175\. Ruscetti, F.W. and Palladino, M.A.: TGF-beta in the immune
response. [Prog. in Growth Factor Res.]{.underline} 3: 159-175, 1991.

176\. Mikovits, J., Lohrey, N., Schuloff, R., Courtless, J., and
Ruscetti, F.: Immune activation of HIV expression from latently infected
monocytes from asymptomatic seropositive patients. [J. Clin.
Invest.]{.underline} 90: 1486-1491, 1992

177\. Wiltrout, R., Damia, G., MacPhee, M., Futami, H., Faltynek, C.,
Ruscetti, F., and Komschilies, K.: Cytokine-based combined modality
approaches to the treatment of murine renal cancer. In: [Cancer
Treatment: New Therapeutic Approaches]{.underline}, Goldstein, A. (Ed),
Plenum Press, NY, 1992, pp. 269-274.

178\. Ruscetti, F., Dubois, C., Jacobsen, S. E., and Keller, J.:
Transforming growth factor-beta and interleukin 1: A paradigm for
opposing regulation of hematopoiesis. In: [Growth Factors in
Haemopoiesis Bailliere\'s Clinical Hematology]{.underline}, Lord, B. and
Dexter, T. (Eds), W.B. Saunders Company, London, 1992, 703-721.

179\. Damia G., Komschilies, K., Faltynek, C., Ruscetti, F., and
Wiltrout R.: Administration of recombinant human interleukin 7 alters
the pattern of myeloid progenitor differentiation in mice.
[Blood]{.underline} 79: 1121-1129, 1992.

180\. McNiece, I., Bertoncello, I., Keller, J., Ruscetti, F. Hartley,
C., and Zsebo, K.: Transforming growth factor-beta inhibits the action
of stem cell factor on mouse and human hematopoietic progenitors. [Intl.
J. Cell Cloning]{.underline}, 10: 80-86, 1992.

181\. Jacobsen, S. E. W., Ruscetti, F., Dubois, C., Wine, J., and
Keller, J.R.: Induction of CSF receptor expression on hematopoietic
progenitor cells: Proposed mechanism for growth factor synergism.
[Blood]{.underline} 80: 678-687, 1992.

182\. Jacobsen, S.E., Ruscetti F., Dubois, C., and Keller, J.: Tumor
necrosis factor alpha is a bidirectional modulator of CSF receptor
expression on hematopoietic progenitor cells: Proposed mechanisms of
action for its multifunctional effects in hematopoiesis. [J. Exp.
Med.]{.underline} 175: 1759-1772, 1992.

183\. Dubois, C., Ruscetti, F., Jacobsen S. E., Oppenheim, J., and
Keller, J.: Hematopoietic growth factors upregulate the p65 type II IL-1
receptor on bone marrow progenitor cells in vitro. [Blood]{.underline}
80: 600-608, 1992.

184\. Damia, G., Komschlies, K., Futami, H., Back, T., Gruys, E., Longo,
D.L., Ruscetti, F., and Wiltrout, R.: Prevention of acute
chemotherapy-induced death in mice by rhIL-1: Protection from
hematological and non-hematological toxicities. [Cancer
Res.]{.underline} 52: 4082-4089, 1992.

185\. Engelmann, G., Boehm, K., Sparks, M., and Ruscetti, F.:
Transforming growth factor-β1 in the developing neo-natal heart of
spontaneously hypertensive and normotensive rats. [Mech. of
Develop.]{.underline} 38: 85-98, 1992.

186\. Loughran, T., Coyle T., Sherman, M., Starkebaum, G., Ehrlich, G.,
Ruscetti, F., and Poiesz, B.: Human T-cell leukemia/lymphoma virus, type
II in a patient with LGL Leukemia. [Blood]{.underline} 80: 1116-1119,
1992.

187\. Hestdal, K., Jacobsen, S.E., Ruscetti, F., Dubois, C., Longo,
D.L., Chizzonite, R., Oppenheim, J., and Keller, J.: In vivo effect of
IL-α1 on hematopoiesis: Role of colony stimulating factor receptor
modulation. [Blood]{.underline} 80: 2486-2494, 1992.

188\. Hoffman, P., Dhib-Jalbut, S., Mikovits, J., Robbins, D., Wolf, A.,
Bergey, G., Lohrey, N., Weislow, O., and Ruscetti, F.: HTLV-1 infection
of monocytes and microglial cells in primary human cultures. [Proc.
Natl. Acad. Sci.]{.underline} 89: 11784-11788, 1992.

189\. Engelmann, G., Birchenall-Roberts, M., Ruscetti, F., and Samarel,
A.: Formation of fetal rat cardiac cell clones by retroviral
transformation: retention of select myocyte characteristics. [J. Mol. &
Cell. Cardiol.]{.underline} 25: 197-213, 1993.

190\. West, M., Mikovits, J., Princler, G., Liu, Y-L., Ruscetti, F.,
Kung, H-F., and Raziuddin.: Characterization and purification of a novel
transcriptional repressor from Hela Cell nuclear extracts recognizing
the negative regulatory element of HIV-1 Long Terminal Repeat. [J. Biol.
Chem.]{.underline} 267: 24948-24952, 1992.

191\. Dubois, C.M., Neta, R., Keller, J.R., Jacobsen, S.E.W., Oppenheim,
J.J., and Ruscetti, F.W.: Hematopoietic growth factors and
glucocorticoids synergize to promote hematopoiesis *in vivo* partly
through induction of IL-1 receptor expression on bone marrow cells.
[Exp. Hematol.]{.underline} 21: 303-310, 1993.

192\. Hestdal, K., Jacobsen, S.E.W., Ruscetti, F., Longo, D.L.,
Oppenheim, J., and Keller, J.: Increased granulopoiesis after sequential
administration of transforming growth factor β1 and
granulocyte-macrophage colony stimulating factor. [Exp.
Hematol.]{.underline} 21: 799-805, 1993.

193\. Jacobsen, S.E., Ruscetti F.W., and Keller, J.R.: Transforming
growth factor-β is a bidirectional modulator of colony stimulating
factor receptor expression on murine bone marrow progenitor cells. [J.
Immunol.]{.underline} 151: 4534-4544, 1993.

194\. Ruscetti, F.W., Varesio, L., Ochoa, A., and Ortaldo, J.:
Pleiotropic effects of transforming growth factor-β on cells of the
immune system. [NY Acad. Sci.]{.underline} 685: 488-500, 1993.

195\. Li, C-C., Ruscetti, F., Rice, N., Chen, E., Mikovits, J., Yang,
N-S., and Longo, D. L.: Differential Expression of Rel family members in
HTLV-1 infected cells: Transcriptional activation of c-rel by tax
protein. [J. Virol.]{.underline} 67: 4205-4213, 1993.

196\. Ruscetti, F.W., Jacobsen, S.E.W., Dubois, C. M., Hestdal, K., and
Keller, J: Hematopoietic cell growth is regulated by balance between
positive and negative regulators: Potential role for receptor
modulation. In: [Negative regulation of hematopoiesis]{.underline},
Guigon, M., et al. (Eds), Colloque INSERM/John Libbey Eurotext Ltd.,
Montrouge France, 229: 23-30, 1993.

197\. Li, B-Q., Tao, F., Yan, Y-D., Baylor, N., Ruscetti, F., and Kung,
H-F.: Inhibition of HIV infection by Baicalin-A Flavonoid compound
purified from Chinese herbal medicine. [Cellular and Molecular
Res.]{.underline} 39: 119-124, 1993.

198\. Loughran, T., Sherman, M., Ruscetti, F.W., Frey, S., Coyle, T.,
Montagna, R., Jones, B., Starkebaum, G., and Poiesz, B.: Prototypical
HTLVI/II is rare in LGL Leukemia. [Leukemia Res.]{.underline} 18:
423-429, 1994.

199\. Grzegorzewski, K., Komschlies, K.L., Mori, M. Kaneda, K., Usui,
N., Faltynek, C.R., Keller, J.R., Ruscetti, F.W., and Wiltrout, R.H.:
Administration of recombinant human interleukin-7 to mice induces the
exportation of myeloid progenitor cells from the bone marrow to
peripheral sites. [Blood]{.underline} 83: 377-385, 1994.

200\. Hestdal, K., Welte, K., Lie, S., Keller, J., Ruscetti, F.W., and
Abrahamsen, T.G.: Severe congential neutrophenia: Abnormal growth and
differentiation of myeloid progenitors to G-CSF but normal response to
G-CSF plus SCF. [Blood]{.underline} 82: 2991-2997, 1993.

201\. Dhib-Jalbut, S., Hoffman, P.M., Yamabe, T., Sun, D., Xia, J.,
Eisenberg, H., Bergey, G., and Ruscetti, F.W.: Extracellular HTLV-I
tax-protein induces cytokine production in adult human microglial cells.
[Ann. of Neurol]{.underline}. 36: 787-790, 1994.

202\. Aiello, F.B., Gusella, L., Longo, D.L., Birchenall-Roberts, M.,
Takacs, L., Takei, F., Ruscetti, F., Musiani, P., and Durum, S.K.:
Inducible accessory function of a macrophage cell line. [Immunopharmacol
Immunotoxicol]{.underline} 15: 327-353, 1993.

203\. de Jong, R., van Lier, R., Ruscetti, F., Schmitt, C., Debre, P.,
and Mossalayi, M. J.: Differential effect of transforming growth factor-
β1 on activation of human naive and memory CD4+ T lymphocytes. [Int'l.
Immunol.]{.underline} 6: 631-638, 1994.

204\. Dubois, C., Ruscetti, F., Stankova, J., and Keller, J.:
Transforming growth factor-beta regulates c-kit message stability and
cell-surface expression in hematopoietic progenitors.
[Blood]{.underline} 83: 3138-3145, 1994.

205\. Hestdal, K., Ruscetti, F., Chizzonite, R., Ortiz, M., Gooya, J.,
Longo, D.L., and Keller, J.: Interleukin-1 directly and indirectly
promotes hematopoietic cell growth through type I Interleukin-1
receptor. [Blood]{.underline} 84: 125-132, 1994.

206\. Sing, G. and Ruscetti, F.: Cytomegalovirus: Effects on
hematopoiesis. In: [Viruses as Agents of Haematological
Disease]{.underline}, Young, N. (Ed), Bailliere\'s Clinical Hematology,
W.B. Saunders Company, London, Vol 8, 1995, pp. 149-164.

207\. Jacobsen, S.E., Ruscetti, F., Okkenhaug, C., Lien, E., Ortiz, M.,
Smeland, E., Veiby, O., and Keller, J.: Distinct and direct effects of
IL-1 and IL-6 on colony stimulating factor and stem cell factor induced
proliferation and differentiation of primitive murine bone marrow
progenitors in vitro. [Exp. Hematol.]{.underline} 22: 1064-1069, 1994.

208\. Urba, W., Ruscetti, F., and Clark, J.: Adult T-cell
lymphoma/leukemia. In: [Clinical Oncology]{.underline}, Abeloff, M.,
Armitage, J., Lichter, A., Niederhuber, J. (Eds), Churchill Livingstone
International, NY, 1995, pp. 2173-2190.

209\. Jacobsen, S.E., Ruscetti, F., Ortiz, M., Gooya, J., and Keller,
J.: Growth response of hematopoietic progenitors to cytokines is
determined by the balance between the synergy of multiple stimulators
and negative cooperation of multiple inhibitors. [Exp.
Hematol.]{.underline} 22: 985-989, 1994.

210\. Ruscetti, F.: The hematopoietic effects of interleukin-1 and
interleukin-6. In: Dale, D. and Adamson, J. (Eds): [Current Opinion in
Hematol.]{.underline} 1: 210-215, 1994.

211\. Tiberghien, P., Reynolds, C., Keller, J., Spence, S., Murphy, W.,
Lyons, R., Chiang, W., Longo, D.L., and Ruscetti, F.W.: Ganciclovir
treatment of herpes simplex thymidine kinase-transduced primary T
lymphocytes: An approach for specific in vivo donor T-cell depletion
after bone marrow transplantation. [Blood]{.underline} 84: 1333-1341,
1994.

212\. Mikovits, J.A., Meyers, A.M., Ortaldo, J. R., and Ruscetti, F.W.:
IL-4 and IL-13 have overlapping but distinct effects on HIV production
in monocytes. [J. Leukoc. Biol.]{.underline} 56: 340-346, 1994.

213\. Espinoza-Delgado, I., Bosco, M.C., Musso, T., Mood, K., Ruscetti,
F.W., Longo, D.L., and Varesio, L.: Inhibitory circuits involving
transforming growth factor-β, interferon , and interleukin-2 in human
monocyte activation. [Blood]{.underline} 83: 3332-3338, 1994.

214\. Keller, J., Bartelmez, S., Sitnicka, E., Ruscetti, F., Ortiz, M.,
Gooya, J., and Jacobsen, S.E.W.: Distinct and overlapping direct effects
of macrophage inflammatory protein-1 and transforming growth factor-β
on hematopoietic progenitor/stem cell growth. [Blood]{.underline} 84:
2175-2181, 1994.

215\. Grzegorzewski, K., Ruscetti, F., Usui, N., Damia, G., Longo, D.L.,
Carlino, J., Keller, J., and Wiltrout, R.: Recombinant transforming
growth factor-β1 and β2 protect mice from acutely lethal doses of
5-fluoro-uracil and doxorubicin. [J. Exp. Med.]{.underline} 180:
1047-1057, 1994.

216. Wong, P.M. C., Han, X-D., Ruscetti, F.W., and Chung, S-W.:
     Immortalized hemopoietic cells with stem cell properties.
     [Immunity]{.underline} 1: 571-583, 1994.

217. Grzegorzewski, K., Komschlies, K., Jacobsen, S., Ruscetti, F.,
     Keller, J., and Wiltrout, R.: Mobilization of long term
     reconstituting hematopoietic stem cells in mice by hIL-7. [J. Exp.
     Med.]{.underline} 181: 369-374, 1995.

218. Jacobsen, F., Keller, J., Ruscetti, F., and Jacobsen, S.E.W.:
     Interleukin-4 and interleukin-11: Direct and pure synergistic
     effects on primitive hematopoietic progenitor cells. [Exp.
     Hematol.]{.underline} 23: 990-995, 1995.

219. Derse, D., Mikovits, J., Polianova, M., Felber, B., and Ruscetti,
     F.: Virions released from cells transfected with a molecular clone
     of HTLV-1 give rise to primary and secondary infections of T-cells.
     [J. Virol.]{.underline} 69: 1907-1912, 1995.

220. Spence, S., Keller, J. Ruscetti, F., Taylor, K., Gooya, J.,
     Funakoshi, S., Longo, D.L., and Murphy, W.: Engraftment of SCID
     mice by human bone marrow hematopoietic cells cultured in vitro: An
     in vivo model for human gene transfer. [Leukemia]{.underline}, 9
     suppl, 1: 543-547, 1995.

222\. Muszynski, K.W., Ruscetti, F.W., Heidecker, G., Rapp, U.,
Troppmair, J., Gooya, J.M., and Keller, J.: Raf-1 protein is required
for growth factor-induced growth of hematopoietic cells. [J. Exp.
Med.]{.underline} 181: 2189-2199, 1995.

223\. Beckwith, M., Ruscetti, F., Sing, G., Urba, W., and Longo, D.L.:
Anti-IGM induces TGF-β sensitivity in a human B-lymphoma cell line:
Inhibition of growth is associated with a down-regulation of mutant p53.
[Blood]{.underline} 85: 2461-2470, 1995.

224\. Fong, S., Pallansch, L., Mikovits, J., Lackman-Smith, C.,
Ruscetti, F., and Gonda, M.: cis-acting regulatory elements in the
bovine immuno-deficiency virus long terminal repeat.
[Virol.]{.underline} 209: 604-614, 1995.

225\. Mossalayi, M. D., Mentz, F., Ouaaz, F., Dalloul, A. H., Blanc, C.,
Debre, P., and Ruscetti, F.W.: Early human thymocyte proliferation is
regulated by an externally controlled autocrine transforming growth
factor-β1 mechanism. [Blood]{.underline} 85: 3594-3601, 1995.

226\. Turley, J., Fuankoshi, S., Ruscetti, F., Kasper J., Murphy W.,
Longo, D., and Birchenall-Roberts, M.: Growth inhibition and apoptosis
of RL human B lymphoma cells by vitamin E succinate and retinoic acid:
Role for transforming growth factor-β. [Cell Growth & Diff.]{.underline}
6: 655-663, 1995.

227\. Keller, J.R., Ortiz, M., and Ruscetti, F.W.: Steel factor (c-kit
ligand) promotes the survival of hematopoietic progenitor/stem cells in
the absence of cell division. [Blood]{.underline} 86: 1757-1764, 1995.

228\. Murphy, W., Funakoshi, S., Beckwith, M., Rushing, S., Conley D.,
Armitage, R., Fanslow, W., Rager, H., Taub, D., Ruscetti, F., and Longo,
D.L.: Antibodies to CD40 inhibit Epstein-Barr Virus-mediated human
B-cell lymphomagenesis in huPBL-SCID mice. [Blood]{.underline} 86:
1946-1953, 1995.

229\. Birchenall-Roberts, M., Ruscetti, F.W., Kasper, J., Bertolette,
D.C., Yoo, Y.D., Roberts, M.S., Ferris, D.K., and Kim S-J.: Nuclear
Localization of v-Abl leads to complex formation with CREB and
transactivates via CRE motifs. [Mol. Cell. Biol.]{.underline} 15:
6088-6099, 1995.

230\. Ouaaz, F., Ruscetti, F., Dugas, B., Mikovits, J., Agut, H., Debré,
P., and Mossalayi M. D: Effects of IgE immune complexes on HIV-1
replication and cell death in infected U1 monocytes: Involvement of
CD23/FcRII mediated nitric oxide and cyclin AMP pathways. [Mol.
Med.]{.underline} 2: 38-49, 1996.

231\. Bang O., Ruscetti F., Lee, M., Kim S-J., and Birchenall-Roberts,
M.: Transforming growth factor-β1 modulates p107 function in myeloid
cells. [J. Biol. Chem]{.underline}. 271: 7811-7819, 1996.

232\. Keller J., Ruscetti F., Heidecker G., Linnekin D., Rapp U.,
Troppmain J., Gooya J., and Muszynski K.: The effect of c-raf antisense
oligonucleotides on growth factor-induced proliferation of hematopoietic
cells. [Current Topics in Microbiol. & Immunol]{.underline}. 211: 43-54,
1996.

233\. Mikovits, J., Hoffman, P., Rethwilm, A., and Ruscetti, F: *In
vitro* infection of primary and retroviral infected human leukocytes by
human foamy virus. [J. Virol.]{.underline} 70: 2774-2779, 1996.

234\. Schwarzenberger, P., Spence, S., Lohrey, N., Kmiecik, T., Longo,
D.L., Murphy, W., Ruscetti, F., and Keller, J.: Gene transfer of
multidrug resistance into a factor dependent human hematopoietic
progenitor cell line: In vivo model for genetically transferred
chemoprotection. [Blood]{.underline} 87: 2723-2731, 1996.

235\. Schwarzenberger, P., Spence, S., Lohrey, N., Kmiecik, T., Longo,
D.L., Murphy, W., Ruscetti, F., and Keller, J.: Targeted gene transfer
to human hematopoietic progenitor cell lines through the c-kit receptor.
[Blood]{.underline} 87: 472-478, 1996.

236\. Linnekin, D., Weiler, S., Mou, S., DeBerry, C., Keller, J.,
Ruscetti, F., Ferris, D., and Longo, D.L.: JAK2 is constitutively
associated with c-kit and is phosphorylated in response to stem cell
factor. [Blood]{.underline} 87: 3688-3693, 1996.

237\. Keller, J., Gooya, J., and Ruscetti, F.: The direct synergistic
effects of leukemia inhibitory factor on hematopioetic progenitor cell
growth: Comparison with other hematopoietins that utilize the gp130
receptor subunit. [Blood]{.underline} 88: 863-869, 1996.

238\. Derse, D., Mikovits, J., Waters, D., Brining S., and Ruscetti, F.:
Examining the molecular genetics of HTLV-1 with an infectious molecular
clone and permissive cell culture systems. [J. AIDS and Human
Retrovirol.]{.underline} 12: 1-5, 1996.

239. Sitnicka, E., Ruscetti, F., Priestley, G, Wolf, N., and Bartelmez,
     S: Transforming Growth Factor-β directly and reversibly inhibits
     the initial cell divisions of long-term repopulating hematopoietic
     stem cells. [Blood]{.underline} 88: 82-88, 1996.

240. Keller, J., Muszynski, K., Gooya, J., Roppmair, J., Rapp, U.,
     Linnekin D., Heidecker, G., and Ruscetti, F.: The effect of c-raf
     antisense oligonucleotides on growth factor induced proliferation
     of hematopoietic cells. [Curr. Top. Microbiol.
     Immunol.]{.underline} 211: 43-53, 1996.

241. Birchenall-Roberts, M.C., Kim, S-J., Bertolette, D.C., Turley,
     J.M., Fu, T., Bang,

> O-S., Kasper, J.J., Yoo, Y.D., and Ruscetti, F. W.: p120-v-Abl
> expression overcomes TGF-β1 negative regulation of c-myc transcription
> but not cell growth. [Oncogene]{.underline} 13: 1499-1509, 1996.

242. Turley, J.M., Falk, L.A., Ruscetti, F.W., Kasper, J.J., Francomano,
     T., Fu, T., Bang, O-S., and Birchenall-Roberts, M. C.: TGF-β1drives
     monocytic differentiation of hematopoietic cells. [Cell Growth and
     Diff.]{.underline} 7: 1535-1544, 1996.

243\. Funakoshi, S., Taub, D.D., Asai, O., Hirano, A., Ruscetti, F.W.,
Longo, D.L., and Murphy, W.J.: Effects of CD40 stimulation in the
prevention of human EBV-lymphomagenesis. [Leukemia and
Lymphoma]{.underline} 24: 187-199, 1997.

244\. Birchenall-Roberts, M.C., Yoo, Y.D., Bertolette, D.C., Lee, K-H.,
Turley, J.M., Bang, O-S., Ruscetti, F.W., and Kim, S-J: The p120-v-Abl
protein interacts with E2F-1 and regulates E2F-1 transcriptional
activity. [J. Biol. Chem.]{.underline} 272: 8905-8911, 1997.

245\. Grgurevich, S., Linnekin, D., Musso, T., Zhang, X., Modi, W.,
Varesio, L., Ruscetti, F.W., Ortaldo, J.R., and McVicar, D.W.: The
Csk-like proteins Lsk, Hyl, and MatK represent the same CSK homologous
kinase (ChK) and are regulated by stem cell factor in the
megakaryoblastic cell line, Mo7e. [Growth Factors]{.underline} 14:
103-115, 1997.

246\. Linnekin, D., DeBerry, C.S., Weiler, S.R., Keller, J.R., Ruscetti,
F.W., and Longo, D.L.: Stem cell factor, the JAK-STAT pathway and signal
transduction. [Leuk. Lymphoma]{.underline} 27: 439-444, 1997.

247\. Turley, J., Fu, T., Ruscetti, F., Mikovits, J., Bertolette, D.,
and Birchenall-Roberts, M.: Vitamin E succinate induces Fas-mediated
apoptosis in estrogen receptor negative human breast cancer cells.
[Cancer Res.]{.underline} 57: 881-890, 1997.

248\. Turley, J., Ruscetti, F., Kim, S-J., Fu, T., Gou, V., and
Birchenall-Roberts, M.: Vitamin E succinate inhibits proliferation of
BT-20 human breast cancer cells: increased binding of cyclin A
negatively regulates E2F transcriptional activity. [Cancer
Res]{.underline}. 57: 2688-2675, 1997.

249\. Muszynski, K.W., Ruscetti, F.W., Gooya, J.M., Linnekin, D.M., and
Keller, J.R.: C-raf antisense oligonucleotides inhibit growth
factor-induced synergistic responses in hematopoietic progenitor cells.
[Stem Cells]{.underline} 15: 63-72, 1997.

250\. Derse, D., Mikovits, J., and Ruscetti, F.: X-I and X-II open
reading frames of HTLV-I are not required for virus replication or for
immortalization of primary T-cells in vitro. [Virol]{.underline}. 237:
123-128, 1997.

251. Keller, J., Ruscetti, F., Grzegorzewski, K., Wiltrout, R.,
     Bartelmez, S., Sitnicka, E., and Jacobsen, S. E. W.: Transforming
     growth factor-β, tumor necrosis factor-α and macrophage
     inflammatory protein-1α are bidirectional modulators of
     hematopoietic cell growth. In: [Colony Stimulating Factors,
     Molecular and Cellular Biology, 2nd Ed]{.underline}, Garland, J.,
     Quesenberry, P. and Hilton, W. (Eds), Marcel Dekker Inc., New York,
     NY, 1998, pp 445-466.

252. Ruscetti, F., Birchenall-Roberts, M., McPherson, J., and Wiltrout,
     R: Transforming Growth Factor-β. In: [Cytokines]{.underline},
     Sluis, A. (Ed), Academic Press., New York, NY, 1998, pp. 415-432.

253. Spence, S., Keller, J., Ruscetti, F., McCauslin, C., Gooya, J.,
     Funakoshi, S., Longo, D. L., and Murphy, W.: Engraftment of *ex
     vivo* expanded and cycling human cord blood hematopoietic
     progenitor cells in SCID mice. [Exp. Hematol.]{.underline} 26:
     507-514, 1998.

254. Asai, O., Longo, D.L., Tian, Z-G., Hornung, R., Taub, D.D.,
     Ruscetti, F.W., and Murphy, W.: Suppression of graph-versus-host
     disease and amplification of graft-versus-tumor effects by
     activated NK cells after allogeneic bone marrow transplantation.
     [J. Clin Invest]{.underline}.101: 1835-1842, 1998.

255. Mikovits, J., Taub, D., Turcovski-Corrales, S., and Ruscetti, F.:
     Similar levels of HIV-I replication in human TH1 and TH2 clones.
     [J. Virol]{.underline}. 72: 5231-5238, 1998.

256. Mikovits, J., Young, H., Vertino, P., Pitha, P., Taub, D.,
     Turcovski-Corrales S., Petrow, C., Baylin, S., and Ruscetti, F.:
     HIV-I infection upregulates DNA methyltransferase resulting in de
     novo methylation of the IFN-γ promoter and subsequent
     downregulation of IFN-γ production. [Mol. Cell. Biol]{.underline}.
     18: 5166-5177, 1998.

257. Wang, J-M., Ueda, H., Howard, O.M.Z., Grimm, M.C., Chertov, O.,
     Gong, X., Gong, W., Resau, J., Broder, C., Evans, G., Arthur, L.O.,
     Ruscetti, F., and Oppenheim, J.: HIV-I envelope gp120 inhibits
     monocyte responses to chemokines through CD4 signal-dependent
     chemokine receptor down-regulation. [J. Immunol]{.underline}. 161:
     4309-4317, 1998.

258. Ueda, H., Howard, O.M.Z., Grimm, M.C., Su, S., Gong, W., Evans, G.,
     Ruscetti, F., Oppenheim, J., and Wang, J-M.: HIV-I envelope gp41 is
     a potent inhibitor of chemoattractant receptor expression and
     function in monocytes. [J. Clin. Invest]{.underline}. 102: 504-412,
     1998.

259. Heidecker, G., Munoz, H., Lloyd, P., Hodge, D., Brehm, K.,
     Ruscetti, F., Kuller, L., Firpo, P., Hu, S-L., Morton, W., and
     Beneveniste R.: Sequence Diversity of SIV Mne Nef *in vivo* and *in
     vitro*. [J. Med. Primatol]{.underline}. 27: 73-80, 1998.

260. Heidecker, G., Munoz, H., Lloyd, P., Hodge, D., Ruscetti, F.,
     Morton, W., Hu, S-L., and Beneveniste, R.: Macaque infected with
     cloned simian immunodeficiency virus show recurring nef gene
     alterations. [Virol]{.underline}. 249: 260-274, 1998.

261. Ortiz, M., Wine, J.W., Lohrey, N., Ruscetti, F.W., Spence, S.E.,
     and Keller, J.R.: Functional characterization of a novel
     hematopoietic stem cell and its place in the c-kit maturation
     pathway in bone marrow cell development. [Immunity]{.underline} 10:
     173-182, 1999.

262. Zeller, J.C., Panoskaltsis-Mortari, A., Murphy, W.J., Ruscetti,
     F.W., Narula, S., Roncarolo, M.G., and Blazer, B.R.: Induction of
     CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and
     TGF-beta. [J. Immunol]{.underline}. 163: 3684-3691, 1999.

263. Su, S.B., Ueda, H., Howard, O.M.Z., Grimm, M.C., Gong, W.,
     Ruscetti, F.W., Oppenheim, J.J., and Wang, J.M.: Inhibition of the
     expression and function of chemokine receptors on human CD4+
     leukocytes by HIV-1 envelope protein gp120. [Chem.
     Immunol]{.underline}. 72: 141-160, 1999.

264. Kopp, W., Reynolds, C., and Ruscetti, F.: Immunoassay of cytokines
     and growth factors in biological fluids. In: [Characterization and
     Assay of Cytokines and Growth Factors. Developments in Biological
     Standardization]{.underline}, Brown F., and Mire-Sluis AR (Eds),
     Basel, Karger, Vol 97, 1999, pp. 29-37.

265. Haga, S.B., Fu, S., Karp, J.E., Ross, D.D., Williams, D.M.,
     Hankins, W.D., Behm, F., Ruscetti, F.W., Chang, M., Becton, D.,
     Raimondi, S.C., and Berg, P.E.: BP1, a new homeobox gene is
     freqently expressed in acute leukemias. [Leuk.]{.underline} 14:
     1867-1875, 2000.

266. Welniak, L.A., Tian, A.G., Sun, R., Keller, J.R., Richards, S.,
     Ruscetti, F.W., and Murphy, W.J.: Effects of growth hormone and
     prolactin on hematopoiesis. [Leuk. Lymphoma]{.underline} 38:
     435-445, 2000.

267. Akiyama, Y., Watanabe, M., Maruyama, K., Ruscetti, F.W., Wiltrout,
     R.H., and Yamaguchi, K.: Enhancement of antitumor immunity against
     B16 melanoma tumor using genetically modified dendritic cells to
     produce cytokines. [Gene Ther.]{.underline} 7: 2113-2121, 2000.

268. Li, B.Q., Fu, T., Dongyan, Y., Mikovits, J.A., Ruscetti, F.W., and
     Wang, J.M.: Flavonoid baicalin inhibits HIV-1 infection at the
     level of viral entry. [Biochem. Biophys, Res. Commun]{.underline}.
     276: 534-538, 2000.

269. Park, S.H., Birchenall-Roberts, M.C., Yi, Y., Lee, B.I., Lee, D.G.,
     Bertolette, D.C., Fu, T., Ruscetti, F., and Kim, S-J.: Mechanism of
     induction of TGF-β type II receptor gene expression by v-Src in
     murine myeloid cells. [Cell Growth & Differ.]{.underline} 12: 9-18,
     2001.

270. Li, B-Q., Wetzel, M.A., Mikovits, J.A., Henderson, E.E., Rogers,
     T.J., Gong, W., Le, Y., Ruscetti, F.W., and Wang, J-M.: The
     synthetic peptide WKYMVm attenuates the function of the chemokine
     receptors CCR5 and CSCR4 through activation of the formyl peptide
     receptor like 1. [Blood]{.underline} 97: 2941-2947, 2001.

271. Welniak, L.A., Khaled, A.R., Anver, M.R., Komschlies, K.L.,
     Wiltrout, R.H., Durum, S., Ruscetti, F.R., Blazer, B.R., and
     Murphy, W.J.: Gastrointestinal cells of IL-7 receptor null mice
     exhibit increased sensitivity to irradiation. [J.
     Immunol]{.underline}.166: 2924-2928, 2001.

272. Poiesz, B.J., Papsidero, L.D., Ehrlich G., Sherman, M., Dube, S.,
     Poiesz, M., Dillon, K., Ruscetti, F.W., Slamon, D., Fang, C.,
     Williams, A., Duggan, D., Glaser. J., Gottlieb, A., Goldberg, J.,
     Ratner, L., Phillips, P., Han, T., Friedman-Kien A., Siegal, F.,
     Rai, K., Sawitsky A., Sheremata, L.W.A., Dosik, H., Cunninghan, C.,
     and Montagna, R.: Prevalence of HTLV-1 associated T-cell lymphoma.
     [Am. J. Hemat]{.underline}. 66: 32-38, 2001.

273. Fang, J-Y, Mikovits, J.A., Bagni, R., Petrow-Sadowski, C.L., and
     Ruscetti, F.W.: Infection of lymphoid cells by
     replication-defective HIV-1 increases de novo methylation. [J.
     Virol]{.underline}. 75: 9753-9761, 2001.

274. Mikovits, J., Ruscetti, F., Zhu, W., Bagni, R., Dorjsuren, D., and
     Shoemaker, R.: Potential cellular signatures of viral infections in
     human hemaotpoietic cells. [Disease Markers]{.underline} 17:
     173-178, 2001.

275. Ruscetti, F.W. and Bartelmez, S.H.: Transforming growth factor
     beta, pleiotropic regulator of hematopoietic stem cells: potential
     physiological and clinical relevance. [Int. J.
     Hematol]{.underline}. 74: 18-25, 2001.

276. Ruff, M.R., Melendez-Guerrero, L.M., Yang, Q, Ho, W., Mikovits,
     J.A., Pert, C.B., and Ruscetti, F.W.: Peptide T inhibits HIV-1
     infection mediated by the chemokine receptor-5 (CCR5). [Antiviral
     Res]{.underline}. 52: 63-75, 2001.

277. Lee, J.K., Back, T.C., Komschlies, K.L., Ruscetti, F.W., Young,
     H.A., and Wiltrout, R.H.: Hematopoietic switch from lymphoid to
     granulocytic development in 3LL tumor-bearing mice. [In
     Vivo]{.underline} 15: 255-263, 2001.

278. Oppenheim, J. J. and Ruscetti, F. W.: Cytokines. In: [Medical
     Immunology]{.underline}, Parslow, T., Stites, D., Terr, A., and
     Imboden, J. (Eds), Lange Press, San Francisco, CA, 2001, pp
     148-166.

279. Jones, K.S., Nath, M., Petrow-Sadowski, C., Baines, A.C. Dambach,
     M., Huang, Y., and Ruscetti, F.W.: Similar regulation of cell
     surface human T-cell leukemia virus type 1 (HTLV-1) surface binding
     proteins in cell highly and poorly transduced by HTLV-1 pseudotyped
     virions. [J. Virol]{.underline}. 76: 12723-12734, 2002.

280. Viard, M., Parolini, I., Sargiacomo, M., Fecchi, K., Ramoni, C.,
     Ablan, S., Ruscetti, F.W., Wang, J.M., and Blumenthal, R.: Role of
     cholesterol in human immunodeficiency virus type 1 envelope
     protein-mediated fusion with host cells. [J. Virol]{.underline}.
     76: 11584-11595, 2002.

281. Cao, Z., Flanders, K.C., Bertolette, D., Lyakh, A., Wurthner, J.U.,
     Parks, W.T., Letterio, J.J., Ruscetti, F.W., and Roberts, A.:
     Levels of phospho-Smad2/3 are sensors of the interplay between
     effects of TGF-beta and retinoic acid on monocytic and granulocytic
     differentiation of HL-60 cells. [Blood]{.underline} 101: 498-507,
     2003.

282. Nath, M.D., Ruscetti F.W., Petrow-Sadowski, C., and Jones, K.S.:
     Regulation of the cell surface expression of an HTLV-1-binding
     protein in human T cells during immune activation.
     [Blood]{.underline} 101: 3085-3092, 2003.

283. Ruff, M.R., Polianova, M., Yang, Q.E., Leoung, G.S., Ruscetti,
     F.W., and Pert, C.B.: Update on D-Ala-Peptide T-Amide (DAPTA): A
     viral entry inhibitor that blocks CCR5 chemokine receptors. [Curr.
     HIV Res]{.underline}. 51-67, 2003.

284. Muegge, K., Young, H., Ruscetti, F., and Mikovits, J.: Epigenetic
     control during lymphoid development and immune responses: aberrant
     regulation, viruses, and cancer. [Ann. NY Acad. Sci.]{.underline}
     983: 55-70, 2003.

285. Akel, S., Petrow-Sadowski, C., Laughlin, M.J., and Ruscetti, F.W.:
     Neutralization of autocrine transforming growth factor-β1 in human
     cord blood CD34+CD 38-Lin cells promotes stem cell factor-mediated
     erythropoietin independent early erythroid progenitor development
     and reduces terminal differentiation. [Stem Cells]{.underline} 21:
     557-567, 2003.

286. Polianova, M.T., Ruscetti, F.W., Pert, C.B., Tractenberg, R.E.,
     Leoung, G., Strong, S., and Ruff, M.R.: Antiviral and immunological
     benefits in HIV patients receiving intranasal peptide T (DAPTA).
     [Peptides]{.underline} 24: 1093-1098, 2003.

287. Puri, A., Rawat, S.S., Lin, H.M., Finnegan, C.M., Mikovits, J.,
     Ruscetti, F.W., and Blumenthal, R.: [AIDS]{.underline} 18: 849-858,
     2004.

288. Birchenall-Roberts, M.C., Fu, T., Bang, O.S., Dambach, M., Resau,
     J.H., Sadowski, C.L., Bertolette, D.C., Lee, H.J., Kim, S.J., and
     Ruscetti, F.W.: Tuberous sclerosis complex 2 gene product interacts
     with human SMAD proteins: A molecular link of two tumor suppressor
     pathways. [J. Biol. Chem]{.underline}. 279: 25605-25613, 2004.

289. Finnegan, C.M., Rawat, S.S., Puri, A., Wang, J-M., Ruscetti, F.W.,
     and Blumenthal. R: Ceramide, a target for antiviral therapy. [Proc.
     Natl. Acad. Sci. (USA)]{.underline} 101: 15452-15457, 2004.

290. Taub, D.D., Mikovits, J.A., Nilsson, G., Schaffer, E.M., Key, M.L.,
     Petrow-Sadowski, C., and Ruscetti, F.W. Alterations in mast cell
     functions and survival following in vitro infection of human
     immunodeficiency virus through CXCR4. [Cell. Immunol]{.underline}.
     230: 65-80, 2004.

291\. Ruscetti, F.W. and Bartelmez S.H.: Cell Cycle Control and Check
Points in Hematopoietic Stem Cells. In: [Handbook of Stem
Cells,]{.underline} Lanza R, Balu H, Melton D, Moore, M.A.S., Verfallie,
C, Weissman, I. and West, M. (Eds), Academic Press, Vol 2, pp. 115-126,
2004.

292\. Wielgosz, M., Rauch, D.A., Jones, K.S., Ruscetti, F.R., and
Ratner, L.: Cholesterol dependence of HTLV-1 infection. [AIDS Res. Human
Retroviruses]{.underline} 21: 43-50, 2005.

293\. Jones, K.S., Akel, S., Petrow-Sadowski, C., Huang, Y., Bertolette,
D., and Ruscetti F.W. Induction of human T-cell leukemia type 1 (HTLV-1)
receptors on quiescent naive T lymphocytes by TGF-beta. [J.
Immunol]{.underline}. 174: 4262-4270, 2005.

294\. Polianova, M., Ruscetti, F.W., Pert, C.B., Brener, J., and Ruff,
M.R.: CCR5 is the receptor for the HIV entry inhibitor peptide T
(DAPTA). [Antiviral Res.]{.underline} 67: 83-92, 2005.

295\. Ruscetti, F., Akel. S., and Bartelmez S.H.: Autocrine transforming
growth factor-beta Regulation of hematopoiesis: Many outcomes that
depend on the context. [Oncogene]{.underline} 24: 5751-5763, 2005

296. Jones, K.S., Petrow-Sadowski, C., Huang Y., Bertolette, D., and
     Ruscetti F.W.: Heparan

> sulfate proteoglycans mediate the attachment and entry of human T-cell
> leukemia virus
>
> type 1 (HTLV-1) virions into CD4^+^ T cells. [J. Virol]{.underline}.
> 79: 12692-12702, 2005.

297. Takenouchi, N., Jones, K.S., Lisinski, I., Fugo, K., Yao, K.,
     Cushman, S.W., Ruscetti, F.W., and Jacobson, S.: BLUT1 is not the
     primary binding receptor but is associated with cell-cell
     transmission of HTLV-1. [J. Virol]{.underline}. \[Epub ahead of
     print\]

298. Jones, K.S., Petrow-Sadowski, C., Bertolette, D., Huang, Y., and
     Ruscetti, F.W.: Human T-cell leukemia virus type 1 (HTLV-1) and
     HTLV-2 use different receptor complexes to enter T cells. [J.
     Virol.]{.underline}, 80: 8291-302, 2006.

299. Birchenall-Roberts, M.C., Fu, T., Kim, S-G, Huang, Y.K., Dambach,
     H.M., Resau, J.H., and Ruscetti, F.W.: K-Ras4B proteins are
     expressed in the nucleolus: Interaction with nucleolin. [Biochem.
     Biophys. Res. Commun.]{.underline} 348: 540-549, 2006.

     [IN PRESS]{.underline}

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1.  Letterio, J.J., and Ruscetti, F.W.: Role of TGF-β in myeloid and
    lymphoid homeostatis. In: [TGF-β Biology,]{.underline} Derynck, R.
    (Ed), Cold Spring Harbor Press, Cold Spring Harbor, NY, in press.

    [SUBMITTED]{.underline}

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1.  Akel, S., Bertolette, D., Petrow-Sadowski, C., and Ruscetti, F.W.:
    Crosstalk between the Smad and miotgen activated protein kinase
    (MAPKs) pathways regulate erythroid differentiation of
    erythroleukemia cells induced by TGF-β, activin, hydoxyurea and
    butyrate. [Submitted to Leukemia (2/2006)]{.underline}.

2.  Akel, S., Bertolette, D., Petrow-Sadowski, C., and Ruscetti, F.W.:
    Levels of Smad7 regulate the signaling of Smad2/3 and mitogen
    activated kinases (MAPKs) and control erythroid and megakaryocytic
    differentiation of erythroleukemia cells. [Submitted to Stem Cells
    (2/2006)]{.underline}.

3.  Number range CHAPTEROrtaldo, J.R., Mason, A., Willette-Brown, J.,
    Ruscetti, F.W., Wine, J., Back, T., Stull, T., Bere, E.W.,
    Feigenbaum, L., Winkler-Pickett, R., and Young, H.A.: Modulation of
    lymphocyte function with inhibitory CD2: Loss of NK and NKT
    function. **[Submitted to Blood, 2/15/07.]{.underline}**