**HH3. What are the trends in exposure to environmental pollutants
including across population subgroups and geographic regions?**

+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Table         |        |         |       |     |     |     |    |
| > 104-2O        |        |         |       |     |     |     |    |
| rganophosphate. |        |         |       |     |     |     |    |
| > Geometric     |        |         |       |     |     |     |    |
| > mean and      |        |         |       |     |     |     |    |
| > selected      |        |         |       |     |     |     |    |
| > percentiles   |        |         |       |     |     |     |    |
| > for           |        |         |       |     |     |     |    |
| > unadjusted    |        |         |       |     |     |     |    |
| > and           |        |         |       |     |     |     |    |
| > crea          |        |         |       |     |     |     |    |
| tinine-adjusted |        |         |       |     |     |     |    |
| > urinary       |        |         |       |     |     |     |    |
| >               |        |         |       |     |     |     |    |
|  concentrations |        |         |       |     |     |     |    |
| > of selected   |        |         |       |     |     |     |    |
| >               |        |         |       |     |     |     |    |
| organophosphate |        |         |       |     |     |     |    |
| > metabolites   |        |         |       |     |     |     |    |
| > for the       |        |         |       |     |     |     |    |
| > United States |        |         |       |     |     |     |    |
| > population,   |        |         |       |     |     |     |    |
| > aged 6-59     |        |         |       |     |     |     |    |
| > years,        |        |         |       |     |     |     |    |
| > National      |        |         |       |     |     |     |    |
| > Health and    |        |         |       |     |     |     |    |
| > Nutrition     |        |         |       |     |     |     |    |
| > Examination   |        |         |       |     |     |     |    |
| > Survey        |        |         |       |     |     |     |    |
| > (NHANES),     |        |         |       |     |     |     |    |
| > 1999-2000 and |        |         |       |     |     |     |    |
| > 2001-2002.    |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
|                 | >      | >       | Geom  | >   | >   | >   | >  |
|                 | Survey |  Sample | etric | 50^ | 75^ | 90^ | 95 |
|                 | >      | > Size  | Mean  | th^ | th^ | th^ | ^t |
|                 |  Years |         |       |     |     |     | h^ |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Di            |        |         |       |     |     |     |    |
| methylphosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,949 | NC    | > 0 | > 2 | > 7 | >  |
|                 | 9-2000 | >       |       | .74 | .80 | .90 | 13 |
|                 | >      | > 2,519 | NC    | >   | >   | >   | .0 |
|                 | > 200  |         |       | >   | > 3 | > 8 | >  |
|                 | 1-2002 |         |       |  \< | .25 | .22 | >  |
|                 |        |         |       | LOD |     |     | 13 |
|                 |        |         |       |     |     |     | .4 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,949 | NC    | > 0 | > 2 | > 8 | >  |
| > creatinine\*  | 9-2000 | >       |       | .81 | .93 | .46 | 16 |
|                 | >      | > 2,518 | NC    | >   | >   | >   | .1 |
|                 | > 200  |         |       | >   | > 3 | > 7 | >  |
|                 | 1-2002 |         |       |  \< | .00 | .83 | >  |
|                 |        |         |       | LOD |     |     | 12 |
|                 |        |         |       |     |     |     | .7 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Dimeth        |        |         |       |     |     |     |    |
| ylthiophosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,948 | 1.82  | > 2 | > 1 | > 3 | >  |
|                 | 9-2000 | >       |       | .70 | 0.0 | 8.0 | 46 |
|                 | >      | > 2,518 | NC    | >   | >   | >   | .0 |
|                 | > 200  |         |       | > 0 | > 4 | > 1 | >  |
|                 | 1-2002 |         |       | .45 | .02 | 6.2 | >  |
|                 |        |         |       |     |     |     | 32 |
|                 |        |         |       |     |     |     | .6 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,948 | 1.64  | > 2 | > 9 | > 3 | >  |
| > creatinine\*  | 9-2000 | >       |       | .12 | .57 | 2.0 | 51 |
|                 | >      | > 2,517 | NC    | >   | >   | >   | .0 |
|                 | > 200  |         |       | > 0 | > 3 | > 1 | >  |
|                 | 1-2002 |         |       | .85 | .79 | 3.2 | >  |
|                 |        |         |       |     |     |     | 27 |
|                 |        |         |       |     |     |     | .2 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Dimethyl      |        |         |       |     |     |     |    |
| dithiophosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,949 | NC    | >   | > 2 | > 1 | >  |
|                 | 9-2000 | >       |       |  \< | .30 | 2.0 | 19 |
|                 | >      | > 2,518 | NC    | LOD | >   | >   | .0 |
|                 | > 200  |         |       | >   | > 0 | > 2 | >  |
|                 | 1-2002 |         |       | >   | .89 | .49 | >  |
|                 |        |         |       |  \< |     |     | 4. |
|                 |        |         |       | LOD |     |     | 95 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,949 | NC    | >   | > 1 | > 1 | >  |
| > creatinine\*  | 9-2000 | >       |       |  \< | .86 | 0.1 | 21 |
|                 | >      | > 2,517 | NC    | LOD | >   | >   | .7 |
|                 | > 200  |         |       | >   | > 0 | > 2 | >  |
|                 | 1-2002 |         |       | >   | .67 | .60 | >  |
|                 |        |         |       |  \< |     |     | 5. |
|                 |        |         |       | LOD |     |     | 80 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > D             |        |         |       |     |     |     |    |
| iethylphosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,949 | 1.03  | > 1 | > 3 | > 7 | >  |
|                 | 9-2000 | >       |       | .20 | .10 | .50 | 13 |
|                 | >      | > 2,520 | NC    | >   | >   | >   | .0 |
|                 | > 200  |         |       | >   | > 2 | > 6 | >  |
|                 | 1-2002 |         |       |  \< | .76 | .33 | >  |
|                 |        |         |       | LOD |     |     | 11 |
|                 |        |         |       |     |     |     | .4 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,949 | 0.92  | > 0 | > 2 | > 7 | >  |
| > creatinine\*  | 9-2000 | >       |       | .92 | .73 | .94 | 12 |
|                 | >      | > 2,519 | NC    | >   | >   | >   | .1 |
|                 | > 200  |         |       | >   | > 2 | > 5 | >  |
|                 | 1-2002 |         |       |  \< | .39 | .23 | >  |
|                 |        |         |       | LOD |     |     | 8. |
|                 |        |         |       |     |     |     | 53 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Dieth         |        |         |       |     |     |     |    |
| ylthiophosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,949 | NC    | > 0 | > 0 | > 1 | >  |
|                 | 9-2000 | >       |       | .49 | .76 | .30 | 2. |
|                 | >      | > 2,519 | 0.46  | >   | >   | >   | 20 |
|                 | > 200  |         |       | > 0 | > 1 | > 2 | >  |
|                 | 1-2002 |         |       | .57 | .48 | .46 | >  |
|                 |        |         |       |     |     |     | 3. |
|                 |        |         |       |     |     |     | 94 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,949 | NC    | > 0 | > 0 | > 1 | >  |
| > creatinine\*  | 9-2000 | >       |       | .25 | .71 | .70 | 2. |
|                 | >      | > 2,518 | 0.45  | >   | >   | >   | 64 |
|                 | > 200  |         |       | > 0 | > 1 | > 2 | >  |
|                 | 1-2002 |         |       | .52 | .33 | .84 | >  |
|                 |        |         |       |     |     |     | 4. |
|                 |        |         |       |     |     |     | 61 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > Diethyl       |        |         |       |     |     |     |    |
| dithiophosphate |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/L of urine | > 199  | > 1,949 | NC    | > 0 | > 0 | > 0 | >  |
|                 | 9-2000 | >       |       | .08 | .20 | .47 | 0. |
|                 | >      | > 2,516 | NC    | >   | >   | >   | 87 |
|                 | > 200  |         |       | >   | >   | > 0 | >  |
|                 | 1-2002 |         |       |  \< |  \< | .61 | >  |
|                 |        |         |       | LOD | LOD |     | 0. |
|                 |        |         |       |     |     |     | 83 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| > µg/g of       | > 199  | > 1,949 | NC    | > 0 | > 0 | > 0 | >  |
| > creatinine\*  | 9-2000 | >       |       | .07 | .20 | .55 | 0. |
|                 | >      | > 2,515 | NC    | >   | >   | >   | 86 |
|                 | > 200  |         |       | >   | >   | > 0 | >  |
|                 | 1-2002 |         |       |  \< |  \< | .58 | >  |
|                 |        |         |       | LOD | LOD |     | 1. |
|                 |        |         |       |     |     |     | 01 |
+-----------------+--------+---------+-------+-----+-----+-----+----+
| \* µg per gram  |        |         |       |     |     |     |    |
| of creatinine   |        |         |       |     |     |     |    |
| in urine        |        |         |       |     |     |     |    |
|                 |        |         |       |     |     |     |    |
| \<LOD= Less     |        |         |       |     |     |     |    |
| than the limit  |        |         |       |     |     |     |    |
| of detection of |        |         |       |     |     |     |    |
| the analytical  |        |         |       |     |     |     |    |
| method.         |        |         |       |     |     |     |    |
|                 |        |         |       |     |     |     |    |
| NC= Not         |        |         |       |     |     |     |    |
| calculated --   |        |         |       |     |     |     |    |
| Proportion of   |        |         |       |     |     |     |    |
| results below   |        |         |       |     |     |     |    |
| limit of        |        |         |       |     |     |     |    |
| detection was   |        |         |       |     |     |     |    |
| too high to     |        |         |       |     |     |     |    |
| provide a valid |        |         |       |     |     |     |    |
| result.         |        |         |       |     |     |     |    |
|                 |        |         |       |     |     |     |    |
| > Source:       |        |         |       |     |     |     |    |
|                 |        |         |       |     |     |     |    |
| Centers for     |        |         |       |     |     |     |    |
| Disease Control |        |         |       |     |     |     |    |
| and Prevention. |        |         |       |     |     |     |    |
| Third National  |        |         |       |     |     |     |    |
| Report on Human |        |         |       |     |     |     |    |
| Exposure to     |        |         |       |     |     |     |    |
| Environmental   |        |         |       |     |     |     |    |
| Chemicals. July |        |         |       |     |     |     |    |
| 2005. (Accessed |        |         |       |     |     |     |    |
| August 29,      |        |         |       |     |     |     |    |
| 2005)           |        |         |       |     |     |     |    |
| <http:          |        |         |       |     |     |     |    |
| //www.cdc.gov/e |        |         |       |     |     |     |    |
| xposurereport/3 |        |         |       |     |     |     |    |
| rd/results.htm> |        |         |       |     |     |     |    |
+-----------------+--------+---------+-------+-----+-----+-----+----+