**Supplementary Instructions for Native American Research Centers for
Health (NARCH) Applications in 2004**

Since the NARCH applications can be quite complex, please follow the
instructions in the PHS 398 application book except where noted below.
Please note that [it is essential]{.underline} to use the most current
version of application forms and instructions for the PHS 398 ([updated
09/09/2003]{.underline}). Use of the electronic versions, downloaded
directly from NIH, is strongly encouraged. These can be found at:
<http://grants.nih.gov/grants/funding/phs398/phs398.html> .

**SECTION I -- PHS 398 GENERAL INFORMATION REQUIREMENTS**

I.  **FACE PAGE** (Use Form PHS 398 Form Face Page) (Page 1 \[AA\]).

Item 1. Title of Project. The title should be related to the overall
thrust of the program (e.g. IHS NARCH Program at\_\_\_\_\_\_\_\_\_Tribe
and \_\_\_\_\_\_\_\_\_University) and not to a particular research or
student development project.

Item 2. Response to Specific Request for Application or Program
Announcement. Check the box marked "YES". Under "Number" type in "NOT
GM-04-107" and under "Title" type in the words "Native American Research
Centers for Health (NARCH)."

II. **DESCRIPTION, PERFORMANCE SITES AND KEY PERSONNEL** (Use PHS 398
    Page 2 \[BB\]). In preparing the abstract of the proposed program,
    in addition to the instructions given in Form PHS 398, outline the
    overall program goals and objectives, anticipated outcomes and how
    the proposed research projects relate to achieving these objectives
    and the goals of the IHS NARCH Program.

III. **TABLE OF CONTENTS** (Page 3 \[CC\])

Reviewers may find the application easier to read if the pages in the
NARCH applications are arranged in the order shown in the *Sample* Table
of Contents below. Pages should be numbered consequently at the bottom
throughout the application. Do [not]{.underline} use suffixes such as
5a, 5b.

> ***SAMPLE***
>
> TABLE OF CONTENTS
>
> [SECTION 1 PHS 398 GENERAL INFORMATION REQUIREMENTS]{.underline}

I.  FACE
    PAGE.......................................................................
    1

II. DESCRIPTION, PERFORMANCE SITES AND PERSONNEL.................... 2

III. TABLE OF
     CONTENTS......................................................\...
     3

IV. ADMINISTRATIVE
    BUDGET.................................................... 4

V.  OVERALL SUMMARY
    BUDGET................................................ 5

VI. BIOGRAPHICAL SKETCH OF NARCH DIRECTOR............................ 6

VII. OTHER SUPPORT FOR NARCH DIRECTOR ONLY)........................... 7

VIII. INSTITUTIONAL SETTING AND GENERAL PLAN............................
      8

> [SECTION 2 (2a., 2b., 2c., etc.) -- FORMAT FOR EACH RESEARCH
> PROJECT/PILOT]{.underline}

IX. FACE
    PAGE.....................................................................
    \_\_

X.  DESCRIPTION, PERFORMANCE SITES AND PERSONNEL........ \_\_

XI. TABLE OF CONTENTS...................................................
    \_\_

XII. ADMINISTRATIVE BUDGET.............................................
     \_\_

XIII. OVERALL SUMMARY BUDGET.........................................
      \_\_

XIV. BIOGRAPHICAL SKETCH OF NARCH DIRECTOR.................. \_\_

XV. OTHER SUPPORT FOR NARCH DIRECTOR ONLY)............... \_\_

XVI. INSTITUTIONAL SETTING AND GENERAL PLAN................. \_\_

> [SECTION 3 CHECKLIST (Use Form PHS
> 398)]{.underline}..................................... \_\_

IV and V. **ADMINISTRATIVE BUDGET OVERALL BUDGET SUMMARY**

General Budget Instructions

NARCH proposals should submit two types of budgets:

> \(1\) Overall administrative budget and
>
> \(2\) Budgets for each of the projects.

Each budget must consist of two separate parts:

> \(1\) Detailed Budget for the First 12-Month Period (Form PHS 398 Page
> 4) and
>
> \(2\) Budget for the Entire Proposed Project Period (Form PHS 398 Page
> 5).

Place the administrative budget pages (2 pages) and the overall program
summary budget (2 pages) after the page showing the table of contents.
The budget pages for individual research projects and pilot research
projects (each 2 pages) are placed at the beginning of each individual
project.

Label each budget page in the [bottom right hand corner]{.underline}
(i.e., "Administrative Budget" "Overall Program Summary Budget" or
"Project \# - Name of Investigator").

Follow the budget guidelines in Form PHS 398 instructions. The budget
items should be described in detail, and justify the need for all
requested items. Do not assume that the need is obvious.

An overall summary of the estimated costs for the entire project period
must be included on this page. The total direct and indirect costs for
the entire project period should be entered under item 8 on the face
page.

The total direct and indirect costs for the first 12-month period should
be entered under item 7 on the face page.

Entire Project Period (PHS 398 Page 5)

VI\. **BIOGRAPHICAL SKETCH FOR NARCH DIRECTOR** (Use Form PHS 398 Page
6)

VII. **OTHER SUPPORT (FOR NARCH DIRECTOR ONLY)** (Use Form PHS 398 Page
     6)

VIII. **INSTITUTIONAL SETTING AND GENERAL PLAN** (Use Form PHS 398
      Continuation Pages)

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A.  **[Description of the Partnership]{.underline}**

> (Do not exceed four pages, not including tables and graphs.)

The information below must also be provided in the application. This
information is necessary for determining the appropriateness of the
environment for a NARCH program.

1.  Describe the origins and development of the collaboration through
    the submission of the application.

2.  Briefly summarize, in tabular Form, for each of the past four years,
    the distribution of American Indian/Alaska Native students and
    faculty (number and percentage) for the whole partner institution
    and for each NARCH Program participating school and/or department.

3.  Provide brief evidence of the academic institution's commitment to
    the hiring of American Indian/Alaska Native faculty (including those
    in science departments) and to the training of American
    Indian/Alaska Native students. Briefly describe and summarize any
    significant achievements within the last three years of any
    specialized programs at the institution that have encouraged and
    have helped to recruit/retain American Indian/Alaska Native students
    and faculty in the NARCH Program participating departments.

4.  Provide a brief summary, by year and American Indian/Alaska Native
    group, of the degrees awarded by each proposed NARCH participating
    department for the last four years. Use a separate table for
    undergraduate and graduate students.

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B.  **[Proposed NARCH Program Plan and Its Anticipated Value to the
    Partnership]{.underline}**

> (Do not exceed four pages, not including tables and graphs.)

Provide a concise description of goals and objectives of the overall
NARCH program. Clearly state how the proposed NARCH Program will
enhance/assist the partnership's efforts to provide expanded
opportunities for American Indians/Alaska Natives in biomedical and
health services research, and to strengthen the institutional research
and research training capability. Describe specific measurable
improvements, anticipated as a consequence of NARCH grant, in faculty
accomplishments (e.g. publications, grant applications, grant funds,
etc.). Provide a brief overview of the research interests, stage in
research career (beginning, established, retooling, etc.) and potential
for growth (improvement) of the faculty members applying for research
support as well as availability of senior faculty willing and able to
serve as mentors. Describe the probable research career goals (e.g.
ability to successfully participate in open competition for research
grants) for the individual investigators beyond successful completion of
the proposed research project. Describe the plans and activities to
develop the partnership and the capacities of the individual tribal and
institutional partners, from the submission of the application through
the end of the proposed program. Sufficient information should be
provided so that a proper review can be conducted, e.g., 1) specific
objective(s), 2)rationale for and feasibility of the proposed activity,
3) detailed description of the activity, including a timetable if
appropriate, and 4) resources available.

**SECTION 2 -- FORMAT FOR EACH PROJECT PROPOSED (WHETHER FOR STUDENT
DEVELOPMENT, FACULTY DEVELOPMENT, RESEARCH, OR PILOT RESEARCH)**

(Each Project should have all eight of the parts listed below, where
appropriate, collected together by project)

**I.** The following FACE PAGE replaces Form PHS 398 face page for
individual projects.

**[Investigator(s):]{.underline}** The Project Investigators should be
listed first followed by collaborating investigators, if any, which
should be listed in alphabetical order.

> [**Type of Application**:]{.underline} Indicate whether the project is
> a student development project, faculty development project, regular
> research project, or pilot research project.
>
> [**Protection Against Research Risks**:]{.underline} Provide the
> appropriate information for the proposed research project. See Form
> 398 instructions for information required when human subjects or
> vertebrate animals are involved. Where hazardous conditions or
> substances are involved, details for training and protecting workers
> must be included in Part 4 of the Research Plan: Experimental Design
> and Methods, Form PHS 398.
>
> *SAMPLE FORMAT*
>
> NARCH INDIVIDUAL RESEARCH PROJECT

1\. Descriptive Title: (80 characters or less)

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

2\. Investigator(s)

Last Name First Name MI Degree Departments

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_

3\. Type of Project:

Student Development Project \[ \] Faculty Development Project \[ \]

Regular Research Project \[ \] Pilot Research Project \[ \]

> 4\. Protection Against Research Risks:

A. Will Human Subjects be involved? Yes \[ \] No \[ \]

If yes, what is the status of IRB review? Completed \[ \] Documentation
Enclosed \[ \]

Pending \[ \]

5\. Vertebrate Animals

A. Will Vertebrate Animals be used? Yes \[ \] No \[ \]

B. If yes, list the species\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_and estimate
the number to be used\_\_\_\_\_\_\_\_\_\_\_\_

If yes, what is the status of IACUC review? Completed \[ \]
Documentation Enclosed \[ \] Pending \[ \]

6\. Are there potential hazards to laboratory workers (carcinogens,
pathogens, ionizing radiation, etc.) involved in the proposed research?
No \[ \] Yes \[ \] If yes, identify these below:

A.

B.

C.

D.

**II**. **DESCRIPTION, PERFORMANCE SITES AND PERSONNEL** (Use Form PHS
398 Form Page 2)

**III** **BUDGETS** (Use Form PHS 398 Form Pages 4 and 5)

Prior to preparation of budgets for each project, please carefully
review the Form PHS 398 instructions and also additional instructions
included herein. Allowable costs are outlined in the NARCH Request for
Application. Pay careful attention to instructions for budget
justification on pages 11-13 and on page 5 of form PHS 398.
Justification of budget items should be presented on Form PHS 398 Page 5
and any continuation page(s) required. Individual budget items should be
combined in preparing the Overall Summary Budget, Section I, V.

[Personnel]{.underline}. Technical assistant(s) should be listed
separately. An explanation of the fringe benefits and rates should be
given. The rate should be that applicable for all employees based on
their classification as full time, or part-time, temporary status.

IV. **BIOGRAPHICAL SKETCH FOR EACH PROJECT INVESTIGATOR**

(Use Form PHS 398 Page 6)

V.  **OTHER SUPPORT FOR EACH PROJECT INVESTIGATOR** (Use Form PHS 398
    Page 7)

VI. **RESOURCES** (Use Form PHS 398, Form 8)

VII. **PUBLICATIONS** (Use Form PHS 398, Form 6)

VIII. **PROJECT PLAN** (Use Form PHS 398 Continuation Pages)

**VIII** **Option A: If a Student Development Project is proposed**:

Provide detailed information on plans to provide opportunities for
students to become acquainted with and to participate in biomedical or
health services research, including interaction with American
Indian/Alaska Native role models.

Information required includes: i) goals and specific objective, ii)
rationale for and feasibility of the approach chose, iii)detailed
description of the activity, iv)plan for attracting desired student
pool, v) resources available, including commitments and other
expressions of interest by off-campus scientists, laboratories and/or
other facilities, vi) description of faculty/student involvement, and
vii) evaluation plans and other follow-up activities. Include
timetables.

Examples of supportable student developmental efforts are on-campus
research, seminars, workshops, and informal discussions by visiting
scientists, attendance at regional and national scientific meetings, and
participation in off-campus laboratory, clinical or health services
research and/or didactic research activities at other institutions
conducting high quality research. Other developmental activities may
also be supported.

Describe how students are to be selected to participate in developmental
activities, specifying the criteria to be used.

**VIII** **Option** **B**: **If a Faculty Development Project is
proposed:**

Provide detailed information on plans to provide opportunities for
selected faculty. For each activity include the name, faculty rank, and
tenure status, along with: i) specific objective(s), ii) rationale for
and feasibility of the proposed activity, iii) detailed description of
the activity, including a timetable if appropriate, iv) resources
available; for activities involving participation in an active research
group include letters of commitment and other expressions of interest by
the PI at the potential on-campus or off-campus facilities, and v) plans
for establishing collaborative or other follow-up activities.

**VIII** **Option C: If a Regular Research Project is proposed**:

Follow Form PHS 398 instructions, including page limitations. The
sequential format should be:

> Introduction; (1) Specific Aims; (2) Background and Significance; (3)
> Progress Report/Preliminary Studies; (4) Research Design and Methods;
> (5) Human Subjects; (6) Vertebrate Animals; (7)
> Consultants/Collaborators; (8) Consortium/Contractual arrangements;
> (9) Literature Cited.

**VIII** **Option D: If a Pilot Project Research Project is proposed**:

Follow Form PHS 398 instructions, including page limitations. The
sequential format should be:

Introduction; (1) Specific Aims; (2) Background and Significance; (3)
Progress Report/Preliminary Studies; (4) Research Design and Methods;
(5) Human Subjects; (6) Vertebrate Animals; (7)
Consultants/Collaborators; (8) Consortium/Contractual arrangements; (9)
Literature Cited.

**SECTION 3 CHECKLIST** (Use Form PHS 398)

**SECTION 4 APPENDIX (**List in TABLE OF CONTENTS and item included in
APPENDIX)