+-----------------------------------------------------------------------+
| # For New a                                                           |
| nd Competing Applications (PHS 398) -- DO NOT SUBMIT UNLESS REQUESTED |
|                                                                       |
| # For Non-competing Progre                                            |
| ss Reports (PHS 2590) -- Submit only Active Support for Key Personnel |
+-----------------------------------------------------------------------+
| # PHS 398/2590 OTHER SUPPORT                                          |
+-----------------------------------------------------------------------+

Provide active support for all key personnel. **Other Support includes
all financial resources, whether Federal, non-Federal, commercial or
institutional, available in direct support of an individual\'s research
endeavors, including but not limited to research grants, cooperative
agreements, contracts, and/or institutional awards.** Training awards,
prizes, or gifts do not need to be included.

There is no \"form page\" for other support. Information on other
support should be provided in the *format* shown below, using
continuation pages as necessary. ***Include the principal
investigator\'s name at the top and number consecutively with the rest
of the application.*** The sample below is intended to provide guidance
regarding the type and extent of information requested.

For instructions and information pertaining to the use of and policy for
other support, see Other Support in the PHS 398 Part III, Policies,
Assurances, Definitions, and Other Information.

Note effort devoted to projects must now be measured using person
months. Indicate calendar, academic, and/or summer months associated
with each project.

**Format**

+---------------------------------+-----------------------+-----------+
| **NAME OF INDIVIDUAL**          |                       |           |
|                                 |                       |           |
| [ACTIVE]{.u                     |                       |           |
| nderline}/[PENDING]{.underline} |                       |           |
+---------------------------------+-----------------------+-----------+
| Project Number (Program         | Dates of              | Person    |
| Director/Principal              | Approved/Proposed     | Months    |
| Investigator)                   | Project               |           |
|                                 |                       | (Cal/A    |
| Source                          | Annual Direct Costs   | cademic/\ |
|                                 |                       | Summer)   |
| Title of Project *(or           |                       |           |
| Subproject)*                    |                       |           |
|                                 |                       |           |
| The major goals of this project |                       |           |
| are...                          |                       |           |
+---------------------------------+-----------------------+-----------+
| [OVERLAP]{.underline}           |                       |           |
| *(summarized for each           |                       |           |
| individual)*                    |                       |           |
+---------------------------------+-----------------------+-----------+

**Samples**

**ANDERSON, R.R.**

[ACTIVE]{.underline}

2 R01 HL 00000-13 (Anderson) 3/1/1997 -- 2/28/2002 3.60 calendar

NIH/NHLBI \$186,529

Chloride and Sodium Transport in Airway Epithelial Cells

> The major goals of this project are to define the biochemistry of
> chloride and sodium transport in airway epithelial cells and clone the
> gene(s) involved in transport.

5 R01 HL 00000-07 (Baker) 4/1/1994 -- 3/31/2002 1.20 calendar

NIH/NHLBI \$122,717

Ion Transport in Lungs

The major goal of this project is to study chloride and sodium transport
in normal and diseased lungs.

R000 (Anderson) 9/1/1996 -- 8/31/2002 1.20 calendar

Cystic Fibrosis Foundation \$43,123

Gene Transfer of CFTR to the Airway Epithelium

> The major goals of this project are to identify and isolate airway
> epithelium progenitor cells and express human CFTR in airway
> epithelial cells.

[PENDING]{.underline}

DCB 950000 (Anderson) 12/01/2002 -- 11/30/2004 2.40 calendar

National Science Foundation \$82,163

Liposome Membrane Composition and Function

> The major goals of this project are to define biochemical properties
> of liposome membrane components and maximize liposome uptake into
> cells.

[OVERLAP]{.underline}

There is scientific overlap between aim 2 of NSF DCB 950000 and aim 4 of
the application under consideration. If both are funded, the budgets
will be adjusted appropriately in conjunction with agency staff.

**RICHARDS, L.**

[NONE]{.underline}

**HERNANDEZ, M.**

[ACTIVE]{.underline}

5 R01 CA 00000-07 (Hernandez) 4/1/1995 -- 3/31/2002 3.60 academic

NIH/NCI \$110,532

Gene Therapy for Small Cell Lung Carcinoma

> The major goals of this project are to use viral strategies to express
> the normal p53 gene in human SCLC cell lines and to study the effect
> on growth and invasiveness of the lines.

5 P01 CA 00000-03 (Chen) 7/1/2000 -- 6/30/2002 1.80 academic

NIH/NCI \$104,428 (sub only) 3.00 summer

Mutations in p53 in Progression of Small Cell Lung Carcinoma

> The major goals of this subproject are to define the p53 mutations in
> SCLC and their contribution to tumor progression and metastasis.

BE 00000 (Hernandez) 9/1/1996 -- 8/31/2002 1.80 academic

American Cancer Society \$86,732

p53 Mutations in Breast Cancer

> The major goals of this project are to define the spectrum of p53
> mutations in human breast cancer samples and correlate the results
> with clinical outcome.

[OVERLAP]{.underline}

> Potential commitment overlap for Dr. Hernandez between 5 R01 CA
> 00000-07 and the application under consideration. If the application
> under consideration is funded with Dr. Hernandez committed at 3.60
> person months, Dr. Hernandez will request approval to reduce her
> months on the NCI grant.

**BENNETT, P.**

[ACTIVE]{.underline}

Investigator Award (Bennett) 9/1/1999 -- 8/31/2002 9.00 calendar

Howard Hughes Medical Institute \$581,317

Gene Cloning and Targeting for Neurological Disease Genes

This award supports the PI's program to map and clone the gene(s)
implicated in the development of Alzheimer's disease and to target
expression of the cloned gene(s) to relevant cells.

[OVERLAP]{.underline}: None