Reaction SMILES: [Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([CH2:32][CH2:33][C:34]4C=CC=CC=4)[CH:14]=[C:15]([O:18][CH:19]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:20][N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)[CH:16]=3)[N:11]([CH3:40])[C:10](=[O:41])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C(N1C(CCOC2C=C3C(=CC=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C=C3C(=C(CCC)C=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C=C3C(=C(CCC4C=CC=CC=4)C=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.ClC1C=C(C2C3C(=C(CCC)C(OC(C4C=CC=CC=4)CN4C=CN=C4)=CC=3)N(C)C(=O)C=2)C=CC=1.ClC1C=C(C2C3C(=C(CCC4C=CC=CC=4)C(OC(C4C=CC=CC=4)CN4C=CN=C4)=CC=3)N(C)C(=O)C=2)C=CC=1.C(N1C(CCOC2C=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC)=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC3C=CC=CC=3)=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.ClC1C=CC=CC=1C1C2C(=C(CCC)C(OC(C3C=CC=CC=3)CN3C=CN=C3)=CC=2)OC(=O)C=1.ClC1C=CC=CC=1C1C2C(=C(CCC3C=CC=CC=3)C(OC(C3C=CC=CC=3)CN3C=CN=C3)=CC=2)OC(=O)C=1.C(N1C(CCOC2C=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC)=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC3C=CC=CC=3)=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([CH2:32][CH2:33][CH3:34])[CH:14]=[C:15]([O:18][CH:19]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:20][N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)[CH:16]=3)[N:11]([CH3:40])[C:10](=[O:41])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1
Reactant: Cn1c(=O)cc(-c2cccc(Cl)c2)c2cc(OC(Cn3ccnc3)c3ccccc3)cc(CCc3ccccc3)c21
Agent: CCCc1c(OC(Cn2ccnc2)c2ccccc2)ccc2c(-c3cccc(Cl)c3)cc(=O)n(C)c12
Agent: CCCc1c(OC(Cn2ccnc2)c2ccccc2)ccc2c(-c3ccccc3Cl)cc(=O)oc12
Agent: CCCc1c(OCCc2cncn2Cc2ccccc2)ccc2c(-c3cccc(Cl)c3)cc(=O)n(C)c12
Product: CCCc1cc(OC(Cn2ccnc2)c2ccccc2)cc2c(-c3cccc(Cl)c3)cc(=O)n(C)c12

Procedure:
##STR11## 4-(3-Chloro-phenyl)-6-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR12## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-1H-quinolin-2-one: ##STR13## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR14## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR15## 4-(3-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR16## 4-(3-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR17## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-1H-quinolin-2-one: ##STR18## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR19## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR20## 4-(2-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-8-propyl-chromen-2-one: ##STR21## 4-(2-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-8-phenethyl-chromen-2-one: ##STR22## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-chromen-2-one: ##STR23## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-8-propyl-chromen-2-one: ##STR24## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-8-phenethyl-chromen-2-one: ##STR25##