Reaction SMILES: C[Li].[Cl:3][C:4]1[CH:5]=[C:6]([C:30]([O:32][CH2:33][C:34]2([C:47]3[CH:52]=[CH:51][C:50]([F:53])=[CH:49][CH:48]=3)[CH2:39][CH2:38][N:37]([C:40]([O:42][C:43]([CH3:46])([CH3:45])[CH3:44])=[O:41])[CH2:36][CH2:35]2)=O)[C:7]2[N:11]([CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:19])([CH3:18])[CH3:17])[C:10](=[O:20])[N:9]([CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[C:8]=2[CH:29]=1.[CH:54]1(N(C)C2CCCCC2)CCCCC1>C1(C)C=CC=CC=1.[Cl-].[Cl-].[CH-]1C=CC=C1.[CH-]1C=CC=C1.[Ti+2]>[Cl:3][C:4]1[CH:5]=[C:6]([C:30]([O:32][CH2:33][C:34]2([C:47]3[CH:48]=[CH:49][C:50]([F:53])=[CH:51][CH:52]=3)[CH2:39][CH2:38][N:37]([C:40]([O:42][C:43]([CH3:45])([CH3:46])[CH3:44])=[O:41])[CH2:36][CH2:35]2)=[CH2:54])[C:7]2[N:11]([CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:19])([CH3:17])[CH3:18])[C:10](=[O:20])[N:9]([CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:28])[CH3:27])[C:8]=2[CH:29]=1
Reactant: CN(C1CCCCC1)C1CCCCC1
Reactant: CC(C)(C)OC(=O)N1CCC(COC(=O)c2cc(Cl)cc3c2n(COCC[Si](C)(C)C)c(=O)n3COCC[Si](C)(C)C)(c2ccc(F)cc2)CC1
Agent: [Ti+2]
Agent: [Cl-]
Agent: [Li]C
Solvent: Cc1ccccc1
Product: C=C(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)cc2c1n(COCC[Si](C)(C)C)c(=O)n2COCC[Si](C)(C)C
Temperature: 0 °C
Reaction time: 1 h

Procedure:
General Note: The reaction was run in such a way as to minimize exposure to light. Reactions were run under a layer of foil to block light and the lab lights were turned off while manipulating the reaction mixtures. To a suspension of titanocenedichloride (0.560 g, 2.198 mmol) in toluene (18 mL) at 0° C. was added methyllithium (1.6 M in diethyl ether, 3.4 mL, 5.5 mmol) dropwise. The reaction was stirred at 0° C. for 1 h. The reaction was quenched by addition of 9 mL of a 6% ammonium chloride solution. The heterogeneous mixture was filtered through a course frit and added to the sep funnel. The layers were separated and the organic layer dried over magnesium sulfate. The solution was filtered and treated with (1-(tert-butoxycarbonyl)-4-(4-fluorophenyl)piperidin-4-yl)methyl 6-chloro-2-oxo-1,3-bis((2-(trimethylsilyl)ethoxy)methyl)-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate (0.560 g, 0.733 mmol) and N-cyclohexyl-N-methylcyclohexanamine (0.078 mL, 0.366 mmol) and the mixture concentrated to ca. ⅓ its volume. The bath temperature was maintained at 30° C. while the reaction mixture was being concentrated. The reaction flask was flushed with a stream of nitrogen and fitted with a reflux condenser and the resulting solution was placed in an oil bath preheated to 80° C. The bath temperature was set to 80° C. and stirred at that temperature for 2 h. The reaction was diluted with ˜20 mL of hexanes to precipitate some of the titanocenes with stirring. To decompose the remaining titanocene, silica gel (excess) was added as a solid with vigorous stirring to the suspension at 0° C. The ice bath was removed and stirring continued for 15 min. The resulting suspension was filtered and the resulting pad washed with 25% ethyl acetate/n-hexane. The mother liquor was concentrated and loaded onto a silica gel column (10% ethyl acetate/n-hexane). After several volumes at 10%, the gradient was ramped to 25% ethyl acetate/n-hexane to give 470 mg (84%) as a very faint yellow solid. 1H-NMR (CD3OD, 500 MHz) δ 7.36 (dd, J=8.9, 5.2 Hz, 2H), 7.19 (d, J=2.1 Hz, 1H), 7.02 (m, 2H), 6.84 (d, J=2.1 Hz, 1H), 5.24 (s, 2H), 4.59 (s, 2H), 4.43 (d, J=2.7 Hz, 1H), 4.22 (d, J=2.5 Hz, 1H), 3.78 (s, 2H), 3.69 (m, 2H), 3.54 (t, J=7.8 Hz, 2H), 3.26 (m, 2H), 2.94 (bs, 2H), 2.19 (m, 2H), 1.78 (m, 2H), 1.36 (s, 9H), 0.85 (t, J=7.9 Hz, 2H), 0.66 (t, J=7.9 Hz, 2H), −0.10 (s, 9H), −0.16 (s, 9H); 13C NMR (126 MHz, CD3OD) δ ppm 163.0 (d, J=245 Hz), 158.7, 156.5 (d, J=14 Hz), 139.4 (d, J=3.8 Hz), 131.8, 130.6 (d, J=7.7 Hz), 128.3, 125.6, 125.1, 124.1, 116.3 (d, J=21 Hz), 110.7, 89.2, 81.1, 77.8, 71.6, 67.4, 66.9, 41.8, 33.2, 28.7, 18.63, 18.58, −1.29, −1.32. Mass spec.: 784.01 (MNa)+.