of a false positive screening RNA [HIV] test in a recently exposed person is significant. With the high false positive rate, we do not advocate the routine use of HIV RNA tests to screen asymptomatic people. The high rate of repeat false positive tests in a given sample (50%) suggests a possible biologic mechanism.? ?A small number (15% to 20%) [!] of [ELISA and WB antibody] tests from low-risk patients will be indeterminate and remain so even if repeated over many months.? Semin Perinatol. 1998 Aug;22(4):293-308. ? Minkoff HL , Aids Researcher ?HIV-1 p24 is the HIV-1 protein most prone to ?false-positive? reactions?false-positive reactions have been observed with every single HIV-1 protein.? Clin Chem. 1991;37(10):1667-8. ? Ng V.L. , Aids Researcher ?68% to 89% of all repeatedly reactive ELISA tests are likely to represent false positive results...each year we might expected to find 175 to 209 truly antibody-positive donors [in Minnesota] and between 371 and 1701 falsely positive donors among those who have repeatedly positive screening tests.? New England Journal of Med, 1985;312:1185-8. ? Osterholm MT , et al, Aids Researchers ?In 1990, of 20.2 million HIV tests done in Russia only 112 were confirmed and about 20,000 were false positives, 1991 saw some 30,000 false positives out of 29.4 million tests, with only 66 confirmations...in 1991 alone some 8000 false-positive results were reported in pregnant women, with only 6 confirmations [presumably with the Western Blot test]? Lancet. 1992;339:1548 ? Voevodin A. , Aids Researcher ?One difficulty in assessing the