for providing the screenshots. I don't see anything suspect in the list or processes or the proxy settings. You didn't explicitly state that deleting the opm.db file didn't have any effect, but I assume that was the case. If deleting the opm.db didn't have an effect, I don't really expect this will have an effect either, but please delete the "MBLStore" and "OOBE" folders found in ~/Library/Application Support/Adobe and delete the "AdobeMuse" folder found in ~/Library/Preferences Then launch Muse. It will go through the first launch experience of asking for UI language, AdobeID, etc. Please confirm the result is the same. Is there an error number in the error screen that appears? If not, could you post a screenshot of it? (You'll need to use the browser interface to the forum to include the screenshot.) On launching Muse the same "Please connect to the internet" appears. There is no error number in that screen. Did you mean post a screen shot of the screen without the error number? I am not quite sure I followed that bit. Muse 2.1 includes an error code in virtually every screen of the launch/login process. Can you once again delete your copy of Muse and re-install from this link http://www.adobe.com/go/muse_latest_mac ? (Perhaps I provided the link last time before the server had been updated to point to Muse 2.1.) I am glad to see someone helping out so much with this.  I am having the same issue that the above users are having.  I