Ecstasy (E) / MDMA Ecstasy (E) can lead to emotional openness, euphoria, and an intense, energetic, spiritual high. It can connect people freely and openly with each other, promote deep inner thinking and analysis, or lead to a reduction in cynical or critical thoughts. The main risks with 'E' use are: Dehydration and overheating: The likelihood of this increases if you dance in a crowded, hot club or dance party. Difference in pills: The chemical that gives 'E' its good reputation is MDMA. Because 'E' is illegal, the production of 'E' is unregulated. This means there is no guarantee that what you buy is what you get: ecstasy is often cut with other substances, some of which can be very harmful. (See below for more on the differences between MDMA and 'E'.) Depression: Many users report feeling "down" for a couple of days after using 'E'. Jaw clenching: There is research to show that 'E' users have greater tooth wear than non-users, a product of jaw clenching while high or in the days after an 'E' trip. Water toxicity: You can have serious problems if you drink too much water and do not piss (or sweat if you dance). Drug Class: Entactogen. Individual drugs: MDMA, MDA, MDEA Common Terms: E, Ecstasy, Disco biscuits, MDMA, pills, X. Standard Dose: E is usually sold as a pill. These pills come in various sizes and colours, usually stamped with different logos. "Pure MDMA" usually come in a capsule as a white to off-white