did his dad, does this mean it only gets passed on through the males in my family or do i still have a chance if im a girl? Name: Kirsten Age: 15 Question: my dad has huntingtons disease and my grandad did and do did his dad, does this mean it only gets passed on through the males in my family or do i still have a chance if im a girl? Huntington's Disease is inherited in an autosomal dominant fashion. This means that each child of a person carrying the HD gene has a 1 in 2 or 50% chance of inheriting the gene. Men and women are equally likely to inherit the gene. The fact that your dad, grandfather & great grandfather all had HD is a fluke. That is, the women of the family have been lucky. You are at a 1 in 2 risk of inheriting the gene from your dad. So are your brothers & sisters. If  you or one of  your brothers & sisters has the gene all the otters are still at a 1 in 2 risk of inheriting the gene also. That is, the 1 in 2 risk applies to each child regardless of the gene status of other family members. My mother, elder brother and younger sister all had or have huntingtons. As I am 52 and show no signs can I presume I am free of the desease? The only way to be certain of your gene status and hence