AndreaBozzo/ceres-open-data-index huggingface dataset:
Basic Product Monograph Information for Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

This guidance is intended to harmonize and to update the prescribing information for nonsteroidal anti-inflammatory drugs () indicated for controlling pain and inflammation associated with rheumatic diseases and other less severe conditions. Each Product Monograph is expected to contain objective, adequate and concise information on properties common to the active component and specific to the drug product. It should provide guidance on the safe and effective use of the drug, not only to the practitioner but also to the patient.

Organization: Health Canada | Santé Canada
Questions and Answers: Plain Language Labelling Regulations for Prescription Drugs - document

This document provides information for industry on how Health Canada's Health Products and Food Branch interprets and applies the 2014 Regulations Amending the Food and Drug Regulations (Labelling, Packaging and Brand Names of Drugs for Human Use) for prescription products and those administered or obtained through a health professional. Please note that this includes prescription pharmaceutical drugs, biologic drugs (Schedule D), and radiopharmaceuticals (Schedule C). 

Organization: Health Canada | Santé Canada
Guidance Document: Questions and Answers: Plain Language Labelling Regulations for Non-prescription Drugs

This document provides information for industry on how Health Canada's Health Products and Food Branch interprets and applies the 2014 Regulations Amending the Food and Drug Regulations (Labelling, Packaging and Brand Names of Drugs for Human Use) for non-prescription (Over-the-Counter, OTC) drug products. These amendments are commonly referred to as the Plain Language Labelling (PLL) Regulations. 

Organization: Health Canada | Santé Canada
Labelling requirements for non-prescription drugs guidance document

The safe use of non-prescription drugs depends on consumers being able to identify the desired product and also being able to understand and act upon the information presented. The label and package are the first points of interaction between a health product and a consumer or healthcare professional. Prior to the implementation of the Plain Language Labelling (PLL) initiative, the general practice in Canada was to present key information within blocks of text on the product label. This guidance document provides prescriptive information on the design specifications, required sections of the CDFT, and labelling content.

Organization: Health Canada | Santé Canada
Guidance Document: Pre-market Evaluation of Hepatotoxicity in Health Products

Hepatotoxicity caused by exposure to a drug or non-infectious agent is injury or damage to the liver that may be associated with impaired liver function. This document is intended to provide basic considerations for the detection, assessment, mitigation and reporting requirements of hepatotoxicity caused by human health products, both alone and in the presence of other health products, foods or xenobiotics, prior to market authorization by Health Canada.

Organization: Health Canada | Santé Canada
Guidance for Industry - Product Monographs of Non-Contraceptive Estrogen/Progestin-Containing Products

Health Canada initiated a Hormone Replacement Therapy (HRT) class labelling project in light of new safety information derived from the results of the Women's Health Initiative (WHI) trial and the Women's Health Initiative Memory Study (WHIMS). This document is intended to help the pharmaceutical industry revise the content of the Product Monograph and associated labelling materials. 

Organization: Health Canada | Santé Canada
Guidance Document - Human-Use Antiseptic Drugs

An antiseptic product is considered to be one that inactivates, reduces, prevents or arrests growth of microorganisms with the inherent intent to mitigate or prevent disease. This includes antiseptic products whether they are regulated under the Food and Drug Regulations (FDR) or the Natural Health Products Regulations (NHPR). This guidance document provides recommendations regarding the information considered necessary by Health Canada in order to support these types of claims.

Organization: Health Canada | Santé Canada
Haemodialysis Solutions

This monograph applies to products in the form of liquid concentrate that are intended to be used for acute and chronic haemodialysis. The medicinal ingredients, their concentrations and combinations are restricted to those specified in this monograph. Full justification supported with information in the public domain should be provided for any deviations in ingredients, concentrations and indications. The medicinal ingredients must be identified on product labelling by the names given in this monograph.

Organization: Health Canada | Santé Canada
Guidance when Developing Therapeutic Regimens for the Eradication of Helicobacter pylori in GI diseases

The purpose of this document is to suggest elements for consideration when designing clinical trials dealing with eradication of H. pylori in GI diseases and to outline elements to be reviewed in the submissions. It expands on the design of clinical trials when patients with active duodenal ulcers are included as subjects in clinical trials. For other Hp associated GI diseases, the guide provides elements to be considered in the study design. 

Organization: Health Canada | Santé Canada
Good manufacturing practices guide for drug products (GUI-0001) - Summary

These guidelines interpret the requirements for good manufacturing practices (GMP) in Part C, Division 2 of the Regulations. Guidance documents like this one are meant to help industry and health care professionals understand how to comply with regulations. They also provide guidance to Health Canada staff, so that the rules are enforced in a fair, consistent and effective way across Canada.

Organization: Health Canada | Santé Canada
Guidance Document: Regulatory requirements for Drug Identification Numbers (DINs) - Summary

When Health Canada authorizes a drug to be marketed in Canada, a Drug Identification Number (DIN) is issued to the manufacturer and printed on the package labels. A DIN indicates that the evaluation of the drug determined that it met the relevant requirements of the Food and Drugs Act and its regulations and the drug has a favourable risk/benefit profile. Manufacturers of prescription and non-prescription drugs must obtain a DIN before they are marketed in Canada

Organization: Health Canada | Santé Canada
Guidance Document: Drug Identification Numbers for Schedule C Drugs (Radiopharmaceuticals and Kits)

On December 13, 2017, Health Canada published the Regulations Amending the Food and Drug Regulations (DIN Requirements for Drugs in Dosage Form Listed in Schedule C to the Food and Drugs Act) in Canada Gazette, Part II. The objective of this regulatory amendment is to apply to Schedule C Drugs (radiopharmaceuticals and kits), the requirement to have a Drug Identification Number (DIN) in order for a drug to be sold in Canada. Along with the new requirement for all Schedule C drugs to have a DIN, the labelling requirements have also been updated to reflect the new requirement: instead of requiring the Establishment Licence number to be on the label, there will now be a requirement for the DIN to be on the label.

Organization: Health Canada | Santé Canada
Guideline on Preparation of DIN Submissions

(DIN) has been assigned for that drug and the assignment of the number has not been cancelled pursuant to section C.01.014.6. In the case of a new drug, a new drug submission filed pursuant to Division 8 of the Food and Drug Regulations is regarded as an application for a DIN. When a product is not subject to Division 8, the application is called a DIN submission.

Organization: Health Canada | Santé Canada
Guidance document - Safety and effectiveness requirements for high-level disinfectants and sterilants for use on reusable semi-critical and critical medical devices (2018)

This guidance document outlines the information considered necessary to support the safety and effectiveness of chemical products that are represented for use as high-level disinfectants and sterilants on reusable semi-critical and critical medical devices, which are regulated as medical devices under the Medical Devices Regulations.

Organization: Health Canada | Santé Canada
Emerald Ash Borer Regulated Areas

This dataset represents city, county, district, district municipality, municipality, regional municipality, town, township, and united county boundaries for the Emerald Ash Borer regulated areas of Canada.File naming convention:Three-letter Pest's scientific name + Geographic Area Abbreviation + Layer Content Abbreviation + Region. Example: aplCANregr == apl (Agrilus planipennis) + CAN (Canada) + reg (Regulated) + r (Region).

Organization: Canadian Food Inspection Agency | Agence canadienne d'inspection des aliments
Hemlock Woolly Adelgid Regulated Areas

To slow the spread of the Hemlock woolly adelgid to new areas, the Canadian Food Inspection Agency (CFIA) uses measures to control the movement of potentially infested materials. Slowing the spread of HWA will protect Canada's environment and forest resources. It also helps keep international markets open to the forest industry and nurseries in non-regulated parts of Nova Scotia and in non-regulated parts of Canada.

Organization: Canadian Food Inspection Agency | Agence canadienne d'inspection des aliments
Brown Spruce Longhorn Beetle Regulated Areas

To slow the spread of the Brown spruce longhorn beetle to new areas, the Canadian Food Inspection Agency (CFIA) uses measures to control the movement of potentially infested materials. Slowing the spread of the Brown spruce longhorn beetle will protect Canada's environment and forest resources. It also helps keep international markets open to the forest industry and nurseries in non-regulated parts of Ontario and Quebec and in the rest of Canada.

Organization: Canadian Food Inspection Agency | Agence canadienne d'inspection des aliments
Asian Longhorned Beetle Regulated Areas

The Canadian Food Inspection Agency (CFIA) established a regulated area as part of its efforts to eradicate the Asian longhorned beetle (ALHB). With the regulation of this area, there are restrictions on the movement of nursery stock, trees, logs, lumber, wood, wood chips and bark chips from certain deciduous trees identified as hosts of the ALHB and firewood of all species. These restrictions are necessary to prevent the spread of the ALHB. This protects Canada's environment and forest resources, and also helps keep international markets open to the forest industry and nurseries in non-regulated parts of Ontario and in the rest of Canada.

Organization: Canadian Food Inspection Agency | Agence canadienne d'inspection des aliments
Extended dose intervals for COVID-19 vaccines to optimize early vaccine rollout and population protection in Canada in the context of limited vaccine supply

Contains NACI's independent advice and recommendations, which are based upon the best current available scientific knowledge. The objective is to provide guidance for the equitable, ethical, and efficient allocation of authorized COVID-19 vaccines in the context of staggered arrival of vaccine supply.

Organization: Public Health Agency of Canada | Agence de la santé publique du Canada
Access Consortium statement on COVID-19 vaccines evidence

The medicine regulators from Australia, Canada, Singapore, Switzerland and the United Kingdom (Access Consortium) have discussed the regulatory evidence requirements for COVID-19 vaccine approvals and considerations for post-market pharmacovigilance. This collective statement on COVID-19 vaccines builds on the Consortium's May 2020 pledge to work together to counter the COVID-19 global pandemic. 

Organization: Health Canada | Santé Canada
Interim guide on isopropyl alcohol for use in alcohol-based hand sanitizers and disinfectants: Overview

Health Canada developed a licensing approach to produce and distribute alcohol-based hand sanitizers on March 27, 2020 (updated on July 13, 2020) for companies. The guide has useful information on the authorizations required to manufacture, package, label, import and/or distribute alcohol-based hand sanitizers. It also includes information on how to obtain the required authorizations (a product licence and/or a site licence) during this emergency.

Organization: Health Canada | Santé Canada
Guidance on safety and performance specifications for filtering facepiece respirators (FFRs) during COVID-19: Background 

The Minister of Health signed the Interim Order Respecting the Importation and Sale of Medical Devices for Use in Relation to COVID-19 on March 18, 2020. A second Interim Order was introduced on March 1, 2021 and replaced the first one. The Interim Order (IO) expedites the authorization of Class I to IV medical devices used for COVID-19: sets out the safety, effectiveness and quality requirements for filtering facepiece respirators (FFRs) and provides criteria for Canadian manufacturers developing respirators in Canada

Organization: Health Canada | Santé Canada
Interim order regulating certain UV radiation-emitting and ozone-generating devices under the Pest Control Products Act: Notice

The Interim Order Respecting Ultraviolet Radiation-emitting Devices and Ozone-generating Devices under the Pest Control Products Act was made on June 7, 2021. This interim order (IO) applies to devices used to control, destroy, make inactive or reduce the level of bacteria, viruses and other micro-organisms that are human pathogens. 

Organization: Health Canada | Santé Canada
Short Rotation Woody Crop Site Suitability: Hybrid Poplar

This data depicts site suitability for the establishment of area-based Short Rotation Woody Crops (SRWC) of hybrid poplar on lands eligible (i.e. non-forested) for afforestation across Canada.  
  
  Determining the feasibility of a large-scale afforestation program is one approach being investigated by the Government of Canada to increase Canada's potential to sequester carbon from the atmosphere and/or produce bioproducts and bioenergy. Large-scale afforestation, however, requires knowledge of where it is suitable to establish and grow trees. Spatial models based on Boolean logic and/or statistical models within a geographic information system may be used for this purpose, but empirical environmental data are often lacking, and the association of these data to land suitability is most often a subjective process. As a solution to this problem, a fuzzy-logic modeling approach to assess site suitability for afforestation of hybrid poplar (Populus spp.) and willow (Salix spp.) in Canada was developed. Expert knowledge regarding the selection and magnitudes of environmental variables were integrated into fuzzy rule sets from which estimates of site suitability were generated and spatially presented. The environmental variables selected included growing season precipitation, climate moisture index, growing degree days, the Canada Land Inventory capability for agriculture and elevation.   
  
  Site suitability is generally defined as the fitness of a given type of land for a particular use. For this assessment, site suitability was defined as the fitness of edaphic, climatic and topographic conditions to establish and grow SRWC species at rates 8 times those of native species. Suitability index values range from 1-100, with higher values corresponding to higher suitability. Approximately 246,000 km2, or 38% of the eligible land base within Canada was found to be suitable for afforestation using Short Rotation Woody Crops (SRWC) of hybrid poplar and/or willow.

Organization: Natural Resources Canada | Ressources naturelles Canada
Symptoms of posttraumatic stress disorder (PTSD) during the COVID-19 pandemic

PTSD is a mental disorder that can happen after exposure to potentially psychologically traumatic events (e.g., actual or threatened death, natural disasters, violence). Symptoms of PTSD include recurring and distressing memories, avoiding reminders of the event(s), and disturbed sleep. The COVID-19 pandemic has impacted individuals, families, and communities in many ways. Stressors from the pandemic may increase the number of Canadians experiencing symptoms of PTSD. Those who already had PTSD may experience more severe symptoms.

Organization: Public Health Agency of Canada | Agence de la santé publique du Canada
Symptoms of anxiety and depression during the COVID-19 pandemic

The COVID-19 pandemic has affected individuals, families, and communities in several ways. Almost 7 out of 10 Canadians reported being negatively impacted by COVID-19. Almost 2 out of 5 Canadians reported some level of distress in the past month. With social distancing and repeated lockdown measures, feelings of isolation and loneliness can increase levels of anxiety and depression.

Organization: Public Health Agency of Canada | Agence de la santé publique du Canada
A Common Vision for increasing physical activity and reducing sedentary living in Canada: Let’s Get Moving

A Common Vision for Increasing Physical Activity and Reducing Sedentary Living in Canada: Let’s Get Moving is the first-ever call to action of its kind in Canada. Never before has Canada had a singular policy focus on physical activity and its relationship to sport, recreation, health, as well as other relevant policy areas.  What’s more, this document also addresses the critical issue of sedentary living. It is a new, collective way forward that will guide the country towards ways of increasing physical activity and reducing sedentary living in Canada.  It is a national policy document that is intended to move the country.

Organization: Public Health Agency of Canada | Agence de la santé publique du Canada
Evaluation of National Microbiology Laboratory 2014-15 to 2018-19

As part of the Public Health Agency of Canada (PHAC), the National Microbiology Laboratory (NML) works with provincial, national, and international public health and laboratory partners to prevent the spread of infectious diseases. It does so by conducting laboratory-based surveillance and applied and discovery research, as well as helping to prepare for public health emergencies and responding to outbreaks. The NML is also part of multiple networks. One of its key functions is to provide leadership and capacity development in the area of infectious diseases, both domestically and internationally.

Organization: Public Health Agency of Canada | Agence de la santé publique du Canada
Secure, Reliable and Easy to Access: Transforming Your Experience with the Government of Canada

This Digital Strategy reinforces SSC's role as the IT engine of government and the lead for IT modernization throughout the Government of Canada. It details the work underway to deliver quality digital services to Canadians and SSC is involved in each one:
	
Modernize how the government replaces, builds and manages major IT systems;
	Provide services to people when and where they need them;
	Take a coordinated approach to digital operations; and
	Transform how SSC works.

Organization: Shared Services Canada | Services partagés Canada
Canada - Grid Spacing: 2km - Gravity - Observed

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canada - Grid Spacing: 2km - Gravity - Bouguer

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canada - Grid Spacing: 2km - Gravity - 1st Vertical Derivative

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canada - Grid Spacing: 2km - Gravity - Isostatic Residual

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canada - Grid Spacing: 2km - Gravity - Gravity Anomalies

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canada - Grid Spacing: 2km - Gravity - Free Air

The Canadian Gravity Anomaly Data Base consists of approximately 660 000 gravity observations, including 165 000 on land, acquired between 1944 and the present. The data spacing ranges from less than 1 km to over 20 km, with an average spacing between 5 and 10 km. All measurements were reduced to the IGSN71 datum. Theoretical gravity values were calculated from the Geodetic Reference System 1967 (GRS67) gravity formula. Bouguer anomalies were calculated using a vertical gravity gradient of 0.3086 mGal·m-1 and a crustal density of 2 670 kg·m-3.

Organization: Natural Resources Canada | Ressources naturelles Canada
Canadian Crude Oil Exports: A 30 Year Review

The Canada Energy Regulator (CER) and Statistics Canada have combined expertise to put together a 30-year look back at the evolution of Canadian crude oil exports. This retrospective highlights some of the factors that influenced the trends in Canadian crude oil exports, coupled with other key indicators, including impacts on Canadian balance of trade, crude oil production, and industry investment. These datasets provide historical Canadian crude oil production, export and import values, investment, trade balance and export values for products categorized by NAPCS Group Codefor 1991 to 2019.  These data were compiled by the Canada Energy Regulator and Statistics Canada.

Organization: Canada Energy Regulator | La Régie de l’énergie du Canada