AndreaBozzo/ceres-open-data-index huggingface dataset:
Metformin: Environmental fate and effects on freshwater plankton

Zooplankton and phytoplankton were collected during the 56-day metformin in-lake mesocosm exposure conducted Lake 114 at the International Institute for Sustainable Development-Experimental Lakes Area (IILSD-ELA) in northern Ontario, Canada. Samples were collected three times throughout the exposure (beginning, middle and end) and analysed under microscope to determine species diversity and total counts. Biomass of phytoplankton was also calculated. The experiment consisted of three metformin treatments (0, 4, and 40 μg/L) each with 4 replicates for a total of 12 mesocosms.


Supplemental Information


Supporting projects: Chemicals Management Plan (CMP)


The Chemicals Management Plan (CMP) is a Government of Canada initiative aimed at reducing the risks posed by chemicals to Canadians and their environment. A key element of the Chemicals Management Plan is the monitoring and surveillance of levels of harmful chemicals in Canadians and their environment. Monitoring and surveillance are essential to identify and track exposure to hazards in the environment and associated health implications. Monitoring and surveillance programs provide the basis for making sound and effective public health and environmental health policies and interventions, as well as measuring the efficacy of control measures.


In support of the Chemicals Management Plan, monitoring and surveillance initiatives were established to support Health Canada and Environment and Climate Change Canada scientists, in collaboration with external partners and researchers, to advance our knowledge. This initiative has allowed the Government of Canada to increase its commitment to a number of existing monitoring initiatives, as well as to support new efforts.


For more information on the Chemicals Management Plan, please visit: https://www.canada.ca/en/health-canada/services/chemical-substances/chemicals-management-plan.html

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Whitemans Creek Water Quality

Stream sampling was conducted in the Whitemans Creek watershed in February 2012 to assess water quality during winter baseflow conditions.  A total of 30 stream sites were sampled where streams in the watershed intersected roadways.  In addition to conventional water quality parameters (e.g., major anions, major cations, ammonium, soluble reactive phosphorus, alkalinity, dissolved organic carbon), stable isotopes of nitrate and sulfate were analyzed to provide insights into the sources of these compounds in the streams. Select artificial sweeteners (acesulfame, cyclamate, saccharin, sucralose) and anionic herbicides (glyphosate, AMPA, 2,4-D, glufosinate, fosamine, MCPA, picloram) were also measured as novel tracers of certain anthropogenic activities that potentially impact water quality.  These data, as well as information on the sampling and analytical methods used, and interpretation of the data, are presented in the report, Water quality snapshot of Whitemans Creek during winter baseflow conditions (https://open-science.canada.ca/items/a9626ada-8a8c-4647-9e02-7efc19c9779a).

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Metformin: Environmental fate and effects on the fathead minnow (Pimephales promelas)

This study aimed to address the toxicological effects the type-2 diabetes drug, metformin has on wild fathead minnows (Pimephales promelas). Fathead minnow embryos and adults were exposed to metformin via in-lake mesocosm and their survival, development and growth was assessed. Exposures were conducted at Lake 114 located at the International Institute for Sustainable Development-Experimental Lakes Area (IILSD-ELA) in northern Ontario, Canada. Adults were exposed for 56 days to three concentrations of metformin (0, 4, and 40 micrograms per liter (ug/L)) each with four replicates. Fish behavior and mortality was observed daily during the exposure period. After 56 days, fish were captured, dissected and assessed for various health endpoints. Additionally, blood, brain and tissue samples were collected for metabolic endpoints. Additionally, wild fathead minnow eggs spawned in the lake were collected in glass mason jars and transported back to the on site laboratory. One fertilized egg was placed in each well for a total of 20 eggs per plate (thus 20 eggs per replicate for the 3 replicates for a total of 60 eggs per mesocosm and a total of 240 eggs per treatment). Hatching time, measurements, survival and deformities were observed.


Supplemental Information


Supporting projects: Chemicals Management Plan (CMP)


The Chemicals Management Plan (CMP) is a Government of Canada initiative aimed at reducing the risks posed by chemicals to Canadians and their environment. A key element of the Chemicals Management Plan is the monitoring and surveillance of levels of harmful chemicals in Canadians and their environment. Monitoring and surveillance are essential to identify and track exposure to hazards in the environment and associated health implications. Monitoring and surveillance programs provide the basis for making sound and effective public health and environmental health policies and interventions, as well as measuring the efficacy of control measures.


In support of the Chemicals Management Plan, monitoring and surveillance initiatives were established to support Health Canada and Environment and Climate Change Canada scientists, in collaboration with external partners and researchers, to advance our knowledge. This initiative has allowed the Government of Canada to increase its commitment to a number of existing monitoring initiatives, as well as to support new efforts.


For more information on the Chemicals Management Plan, please visit: https://www.canada.ca/en/health-canada/services/chemical-substances/chemicals-management-plan.html

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Human exposure to harmful substances

The Canadian Environmental Sustainability Indicators (CESI) program provides data and information to track Canada's performance on key environmental sustainability issues.These indicators present the concentrations of 4 substances (mercury, lead, cadmium and bisphenol A) in the Canadian population for the 6 survey cycles from 2007 to 2019 based on data collected as part of the Canadian Health Measures Survey. These substances were chosen from the Canadian Health Measures Survey because they complement other indicators from the Canadian Environmental Sustainability Indicators program. For each substance, the concentration in blood or urine is provided by age group and by sex when data are available. The Government of Canada uses a variety of methods, tools and models to assess human exposure to environmental chemicals and their potential health effects. Human exposure to chemicals can be estimated indirectly by measuring chemicals in the environment, food or products, or directly by biomonitoring. The Canadian Health Measures Survey measures environmental chemicals and/or their metabolites in blood and urine of participants. These indicators provide a snapshot of the survey results. Information is provided to Canadians in a number of formats including: static and interactive maps, charts and graphs, HTML and CSV data tables and downloadable reports. See the supplementary documentation for the data sources and details on how the data were collected and how the indicator was calculated.

Canadian Environmental Sustainability Indicators: https://www.canada.ca/environmental-indicators

Supplemental Information

Canadian Environmental Sustainability Indicators - Home page:
               https://www.canada.ca/environmental-indicators

               Supporting Projects: Canadian Environmental Sustainability Indicators (CESI)

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Selected T1 Statistics 2022 edition (for the 2021 tax year)

This publication presents statistics for 21 selected T1 line items such as employment income, old age security pension, net federal tax and total tax payable. These line items are presented by province and territory and then further broken down by income class, major source of income, age, and gender. The most recent assessment is used.

Organization: Canada Revenue Agency | Agence du revenu du Canada
Selected T1 Statistics 2023 edition (for the 2022 tax year)

This publication presents statistics for 21 selected T1 line items such as employment income, old age security pension, net federal tax and total tax payable. These line items are presented by province and territory and then further broken down by income class, major source of income, age, and gender. The most recent assessment is used.

Organization: Canada Revenue Agency | Agence du revenu du Canada
Notice: Proposed Modification to Bioequivalence Standards for Multiphasic Modified-Release Drug Products

This Notice serves to inform sponsors of drug submissions pursuant to Division C.08 of the Food and Drug Regulations (i.e., new drug and abbreviated new drug submissions), of proposed modifications to Health Canada’s comparative bioavailability requirements when multiphasic plasma concentration profiles have been demonstrated to be integral to the product’s therapeutic effect.

Organization: Health Canada | Santé Canada
Notice: Phase III of Pre-Market Transparency Initiatives for Prescription Drugs

As a regulator, Health Canada plays an important role in protecting the health and safety of Canadians. Health Canada is committed to being transparent and open about its activities and to making timely and useful information available about health products and health product submissions. Greater transparency and openness with Canadians strengthens the trust in our regulatory decisions, and ultimately supports Canadians in making better decisions about their health.

Organization: Health Canada | Santé Canada
Notice: Medical Device Cybersecurity

In recent years, there has been a dramatic increase in the level of interconnectedness and data exchange between medical devices and their network environments. Increased connectivity in medical devices can: improve access to health care information; facilitate more timely diagnoses and treatments; and, improve access to care for patients. However, it can leave medical devices vulnerable to unauthorized access in a manner similar to computer systems. These vulnerabilities can impact the safety of the medical device by affecting clinical operations, causing diagnostic errors, or causing direct harm to patients.

Organization: Health Canada | Santé Canada
Briefing Package for the hearing before the Standing Committee on Environment and Sustainable Development on 2023 Reports 6 to 10 of the Commissioner of the Environment and Sustainable Development

Briefing Package for the hearing before the Standing Committee on Environment and Sustainable Development on 2023 Reports 6 to 10 of the Commissioner of the Environment and Sustainable Development

Organization: Office of the Auditor General of Canada | Bureau du vérificateur général du Canada
Priority Species for Species at Risk

This dataset displays the Canadian geographic ranges of the priority species identified under the Pan-Canadian Approach for Transforming Species at Risk Conservation in Canada (“Pan-Canadian Approach”). These species include Barren-ground Caribou (including the Dolphin and Union population); Greater Sage-Grouse; Peary Caribou; Wood Bison; Caribou, Boreal population (“Boreal Caribou”); and Woodland Caribou, Southern Mountain population (“Southern Mountain Caribou”). The priority species were chosen following a number of criteria and considerations in collaboration with federal, provincial, and territorial partners. These include, but were not limited to, the species' ecological role on a regional or national scale, their conservation status and achievability of conservation outcomes, their social and cultural value (particularly to Indigenous peoples), and the leadership/partnership opportunities that they present. Delivering conservation outcomes for targeted priority species can have significant co-benefits for other species at risk, and wildlife in general. For more information on the Pan-Canadian Approach and the priority species, see https://www.canada.ca/en/services/environment/wildlife-plants-species/species-risk/pan-canadian-approach.html.  
  
  This dataset includes: 1) the range for the Boreal Caribou (see https://species-registry.canada.ca/index-en.html#/consultations/2253); 2) the local populations for the Southern Mountain Caribou (see https://species-registry.canada.ca/index-en.html#/consultations/1309); 3) the range for the Greater Sage-Grouse (see https://species-registry.canada.ca/index-en.html#/consultations/1458); 4) local populations for the Peary Caribou (see https://species-registry.canada.ca/index-en.html#/consultations/3657); 5) range for the Barren-ground Caribou (see https://www.maps.geomatics.gov.nt.ca/Html5Viewer/index.html?viewer=NWT_SHV English only); 6) range for the Barren-ground Caribou, Dolphin and Union population (https://www.maps.geomatics.gov.nt.ca/Html5Viewer/index.html?viewer=NWT_SHV English only); 7) range for the Wood Bison (see https://species-registry.canada.ca/index-en.html#/consultations/2914).

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Questions and Answers - Access to Drugs in Exceptional Circumstances

Urgent public health needs can occur, for example, during a flu pandemic, situations such as the opioid crisis or a military health emergency. Sometimes a drug that is needed for immediate use to respond to an exceptional public health crisis is not authorized for sale in Canada, but may be authorized for sale in another country. This guidance document provides an overview of the regulatory process under Division 10 of the FDR for the importation of drugs for an urgent public health need and outlines the roles and responsibilities of Health Canada, public health officials, DEL holders, and health care institutions.

Organization: Health Canada | Santé Canada
Opioid Warning Sticker and Patient Information Handout, and Risk Management Plans

Health Canada has identified the need for patients to receive clear information about the safe use of opioids and the risks associated with their use. As such, requirements have been added, under the Food and Drug Regulations, for a warning sticker and patient information handout to be provided with all prescription opioids that appear in Part A of the “List of Opioids”, at the time of dispensing. 

Organization: Health Canada | Santé Canada
Opioid Pain Medications

Opioid pain medications include a broad range of drugs, such as morphine, codeine and oxycodone. When used as directed, opioid pain medications are effective and the side effects (e.g., drowsiness, nausea, constipation, etc.) are generally manageable. However, abuse of these medications can have serious health effects and may lead to addiction.

Organization: Health Canada | Santé Canada
Guidance Document - Supporting Evidence for Implantable Medical Devices Manufactured by 3D Printing

This guidance document is intended to aid manufacturers and regulatory representatives in preparing medical device licence applications for 3D printed medical devices. As with all Class III and IV medical devices, devices produced by additive manufacturing or 3D printing, are subject to the Medical Devices Regulations (Regulations) and require a review of submitted evidence of safety and effectiveness before a licence can be issued.

Organization: Health Canada | Santé Canada
SIU Authorizations: April 1st to September 30th, 2022 (Quarterly Report Q1 & Q2)

Structured Intervention Units (SIUs) were incorporated into the Correctional Service of Canada (CSC) on November 30th, 2019. Such units are intended to provide intervention-focused accommodations to offenders who cannot be safely managed in the mainstream offender population.

Organization: Correctional Service of Canada | Service correctionnel du Canada
Criminal Risk Index Validation for Indigenous and Non-Indigenous Men

Based on the CRI development data, a total of 24,972 men first releases (4,850 Indigenous and 19,996 Non-Indigenous) were gathered over a six-year period (2006-07 to 2011-12) and followed-up for returns to federal custody for any offence within a 3-year period. Cramer’s V and Area under the Curve (AUCs) were computed for overall men, Indigenous and Non-Indigenous.

Organization: Correctional Service of Canada | Service correctionnel du Canada
Regional Profiles of Canadian In-Custody Women Federal Offenders

The current study examined regional profiles for in-custody women at three different time points to further understand these differences and to provide more nuanced findings that can be used to inform future planning around resource allocation, infrastructure needs, and population management. Please note that this report is a one page summary. If you wish to have a copy of the full report, please send a request comment via the Open Government Portal or email the OG team: opengovernmentgen-nhq@csc-scc.gc.ca.

Organization: Correctional Service of Canada | Service correctionnel du Canada
Understanding the Profile Characteristics and Correctional Experiences of Indigenous Federal Offenders: A Review of Research Results

Recognizing the overrepresentation of Indigenous persons in the federal correctional system, the Correctional Service of Canada (CSC) has incorporated a model of Indigenous corrections. This model includes specialized interventions and services at all sentence stages and ongoing knowledge-building efforts to understand the profile and needs of Indigenous offenders. Please note that this report is a one page summary. If you wish to have a copy of the full report, please send a request comment via the Open Government Portal or email the OG team: opengovernmentgen-nhq@csc-scc.gc.ca.

Organization: Correctional Service of Canada | Service correctionnel du Canada
Virtual Correctional Program Delivery: A Literature Review

The Correctional Service of Canada (CSC) delivers in-person correctional programs to target offenders’ criminogenic need areas. However, the COVID-19 pandemic acted as a catalyst to change how CSC delivers these programs. Please note that this report is a one page summary. If you wish to have a copy of the full report, please send a request comment via the Open Government Portal or email the OG team: opengovernmentgen-nhq@csc-scc.gc.ca.

Organization: Correctional Service of Canada | Service correctionnel du Canada
National hydrometric network basin polygons

The Water Survey of Canada (WSC) is the national authority responsible for the collection, interpretation and dissemination of standardized water resource data and information in Canada. In partnership with the provinces, territories and other agencies, WSC operates over 2800 active hydrometric gauges across the country. WSC maintains and provides real-time and historic hydrometric data for some 8000 active and discontinued stations. This dataset consists of a set of polygons that represent the drainage areas of both active and discontinued discharge stations. Users are encouraged to report any errors using the “Contact Us” webpage at: https://weather.gc.ca/mainmenu/contact_us_e.html?site=water

Organization: Environment and Climate Change Canada | Environnement et Changement climatique Canada
Provisional weekly estimates of the number of deaths, expected number of deaths and excess mortality, by age group and sex, inactive

Provisional estimates of excess mortality, adjusted numbers of deaths, and expected numbers of deaths to monitor weekly death trends, by age group and sex, in Canada. Given the delays in receiving the data from the provincial and territorial vital statistics offices, death data have been adjusted to account for undercoverage. Data in this table will be available by province and territory.<br>

Organization: Statistics Canada | Statistique Canada
Debt financing terms and conditions for small and medium enterprises

<p>Debt financing (mortgage, line of credit, term loan, credit card) terms and conditions, average interest rates and average length of term for small and medium enterprises in 2020 by region, CMA level, North American Industry Classification System (NAICS), demographics, age of business, employment size, rate of growth, etc. <br>
</p>


Organization: Statistics Canada | Statistique Canada
Business or organization expectations of inflation to be a bigger issue when discussing wage increases with employees over the next 12 months, second quarter of 2022

<p>Business or organization expectations of inflation to be a bigger issue when discussing wage increases with employees over the next 12 months, North American Industry Classification System (NAICS), business employment size, type of business, business activity and majority ownership, second quarter of 2022.  <br></p>

Organization: Statistics Canada | Statistique Canada
Advanced technology and website adoption for small and medium enterprises

<p>Adoption of advanced technologies (business intelligence, design, security, logistic, processing, internet of things, clean, other) and wesbites by small and medium enterprises in 2020 by region, CMA level, North American Industry Classification System (NAICS), demographics, age of business, employment size, rate of growth, etc. <br></p>

Organization: Statistics Canada | Statistique Canada
Reasons for not adopting advanced technologies by small and medium enterprises

<p>Reasons for small and medium enterprises not adopting advanced technologies  (business intelligence, design, security, logistic, processing, internet of things, clean, other) in 2020 by region, CMA level, North American Industry Classification System (NAICS), demographics, age of business, employment size, rate of growth, etc. <br></p>

Organization: Statistics Canada | Statistique Canada
Interprovincial Migration by Mother Tongue for Interprovincial Migrants Aged 5 Years and Over, Provinces and Territories, 1971 to 2016, inactive

The table provides in-migration, out-migration and net migration counts according to mother tongue for interprovincial migrants in all provinces and territories since 1971. External migrants, intraprovincial migrants, non-migrants and non-movers are not shown. Multiple responses to the mother tongue question were equally redistributed among "English", "French" and "Other" responses.These data are based on the Census of Population and the 2011 National Household Survey.<br>

Organization: Statistics Canada | Statistique Canada
Interprovincial Migration by First Official Language Spoken for Interprovincial Migrants Aged 5 Years and Over, Provinces and Territories, 1971 to 2016, inactive

The table provides in-migration, out-migration and net migration counts according to the first official language spoken for interprovincial migrants in all provinces and territories since 1971. External migrants, intraprovincial migrants, non-migrants and non-movers are not shown. The "English-French" response was equally redistributed among "English" and "French" single responses. These data are based on the Census of Population and the 2011 National Household Survey.<br>

Organization: Statistics Canada | Statistique Canada
OGGO committee briefing binder: Appearance by the Deputy Minister of Employment and Social Development Canada – June 21, 2023

Appearance by the Deputy Minister of Employment and Social Development Canada, Jean-François Tremblay, before the Standing Committee on Government Operations and Estimates (OGGO), Study: Federal Government Consulting Contracts Awarded to McKinsey & Company (redaction and translation of documents), June 21, 2023 

Organization: Employment and Social Development Canada | Emploi et Développement social Canada