AndreaBozzo/ceres-open-data-index huggingface dataset:
National Child Welfare Workforce Institute (NCWWI) Comprehensive Organizational Health Assessment [2014-2019]

Baseline assessments contained approximately 307 items, though the number of items displayed to respondents depended on skip logic, which was based on position and whether the respondent worked directly with families. Between July 2014 and July 2015, 2,832 participants completed the baseline COHA survey. At follow-up (approximately three years later), three measures from the baseline COHA were dropped and four new measures were added. Follow-up assessments contained approximately 340 items, and the number of items displayed to respondents depended on the same skip logic used in the baseline assessment. Between November 2017 and February 2019, 2,912 participants completed the follow-up assessment. A total of 1,034 participants completed both assessments. Items in the baseline and follow-up COHA covered individual-level factors (burnout, coping strategies, exposure to violence, intent to stay, job satisfaction, job stress, secondary trauma, self-efficacy, and time pressure), unit-level factors (peer support, supervision, professional sharing/support, team cohesion, and shared vision), organization-level factors (inclusivity, leadership, learning culture, organizational climate, organizational bias, physical environment, professional development and preparation for work, readiness for change, and workplace prejudice and discrimination) and community-level factors (public perceptions of child welfare, inter-professional collaboration, and community resources).

Investigators: Robin Leake, PhD 
Butler Institute for Families
University of Denver

Shauna L. Rienks, PhD 
Butler Institute for Families 
University of Denver 

Anna de Guzman, M.A. 
Butler Institute for Families 
University of Denver 

Amy S. He, PhD 
Butler Institute for Families 
University of Denver 

Mary Jo Stahlschmidt, PhD 
Butler Institute for Families 
University of Denver
MD COVID-19 - Cases by ZIP Code Archive (2020)

<b>Summary</b>
The cumulative number of positive COVID-19 cases among Maryland residents within a single Maryland ZIP code for the year 2020.

<b>Description</b>
The MD COVID-19 - Cases by ZIP data layer is a collection of positive COVID-19 test results that have been reported each day by the local health department via the NEDSS system.

<b>Terms of Use</b>
The Spatial Data, and the information therein, (collectively the "Data") is provided "as is" without warranty of any kind, either expressed, implied, or statutory. The user assumes the entire risk as to quality and performance of the Data. No guarantee of accuracy is granted, nor is any responsibility for reliance thereon assumed. In no event shall the State of Maryland be liable for direct, indirect, incidental, consequential or special damages of any kind. The State of Maryland does not accept liability for any damages or misrepresentation caused by inaccuracies in the Data or as a result to changes to the Data, nor is there responsibility assumed to maintain the Data in any manner or form. The Data can be freely distributed as long as the metadata entry is not modified or deleted. Any data derived from the Data must acknowledge the State of Maryland in the metadata.

Case data aggregates to ZIP Codes do not reflect cases with missing, out of state, or incorrect ZIP Codes. Therefore, statewide totals of aggregate ZIP Code data may not match other statewide aggregate totals.
Compound 525862: N,N-Dimethyl-2-phenyl-N'-decyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N'-decyl-N,N-dimethyl-2-phenylethanimidamide. Molecular Formula: C20H34N2. Molecular Weight: 302.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526061: trans-Methyl-i-butyl-diazene

Chemical compound data from PubChem database. IUPAC Name: methyl(2-methylpropyl)diazene. Molecular Formula: C5H12N2. Molecular Weight: 100.16. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding

The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is a prospective, randomized, multicenter clinical trial of carotid endarterectomy (CEA) versus carotid artery stenting (CAS) as prevention for stroke in patients with symptomatic stenosis greater than or equal to 50%. CREST is sponsored by the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH), with additional support by a device manufacturer, and will provide data to the US Food and Drug Administration (FDA) for evaluation of a stent device. Because of budget constraints for CREST, Health Care Financing Administration (HCFA) reimbursement for hospital costs incurred by CREST patients will be essential. The involvement of academic scientists, industry, and three separate government agencies (NIH, FDA, HCFA) has presented many challenges in conducting the trial. A review of the pathways followed to meet these challenges may be helpful to others seeking to facilitate sharing of the costs and burdens of conducting innovative clinical research.
National-Level Comparisons of Mental Health Estimates from the National Survey on Drug Use and Health (NSDUH) and Other Data Sources

The main objective of this methodological report is to provide comparisons between NSDUH and other national data sources for adult and adolescent mental health prevalence estimates, updating a previous report comparing 2009 NSDUH estimates with other data sources (Hedden et al., 2012).  Other sources of data are 2001 to 2003 National Comorbidity Survey Replication (NCS-R),  2001 to 2004 National Comorbidity Survey Adolescent Supplement (NCS-A), 2001 to 2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Wave 1, 2012 to 2013 NESARC-III, • 2011 to 2012 Behavioral Risk Factor Surveillance System (BRFSS), 2012 National Health Interview Survey (NHIS), 2012 Medical Expenditure Panel Survey (MEPS), 2011 to 2012 National Survey of Children\'s Health (NSCH), and 2009 and 2011 Youth Risk Behavior Survey (YRBS).
Patent AT-E401025-T1: [Translated] DEVICE FOR PREPARING A DRINK FROM A CARTRIDGE, WITH ACTIVATION AFTER READING AN OPTICAL CODE ON THE CARTRIDGE

In an apparatus for the preparation of a plurality of drinks from cartridges (K) that are provided with an optical code (C) on one of its faces (F) identifying the cartridge (K) itself and the corresponding drink, the reading of the optical code (C) is made more certain and reliable thanks to a projecting reading window (40).
NNDSS - TABLE 1OO. Viral hemorrhagic fevers, Machupo virus to Viral hemorrhagic fevers, Sabia virus

NNDSS - TABLE 1OO. Viral hemorrhagic fevers, Machupo virus to Viral hemorrhagic fevers, Sabia virus - 2019. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents. 

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published — CDC does not have data because of changes in how conditions are categorized.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2018 and 2019 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the US, a US territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-US Residents' category. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf. 
† Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data). 
§ Prior to 2015, CDC's National Notifiable Diseases Surveillance System (NNDSS) did not receive electronic data about incident cases of specific viral hemorrhagic fevers; instead data were collected in aggregate as "viral hemorrhagic fevers'. NNDSS was updated beginning in 2015 to receive data for each of the viral hemorrhagic fevers listed.
Doxycycline-induced expression of sense and inverted-repeat constructs modulates

Background
          A tetracycline-regulated (conditional) system for RNA interference (RNAi) would have many practical applications. Such a strategy was developed using RNAi of the gene for phosphogluconate mutase (Pgm). Pgm is a candidate lifespan regulator: PgmS allele frequency is increased by selection for increased lifespan, whereas PgmM and PgmF allele frequencies are decreased.
        
        
          Results
          The Pgm alleles were cloned and sequenced and were found to differ by amino-acid substitutions consistent with the relative electrophoretic mobilities of the proteins. The 'tet-on' doxycycline-regulated promoter system was used to overexpress PgmS in a wild-type (PgmM) background. Enzyme activity increases of two- to five-fold were observed in five independent transgenic lines. Tet-on was also used to drive expression of an inverted-repeat fragment of Pgm coding region. The inverted-repeat transcript was expected to form a dsRNA hairpin, induce RNAi, and thereby reduce endogenous Pgm gene expression at the RNA level. Endogenous Pgm RNA levels in adult flies were found to be reduced or eliminated by doxycycline treatment in five independent inverted-repeat transgenic lines. Our results show that doxycycline-regulated expression of inverted-repeat constructs can cause a conditional reduction in specific gene expression. The effect of sense and inverted-repeat construct expression on lifespan was assayed in multiple transgenic lines. Under the conditions tested, altered Pgm gene expression had no detectable effect on adult Drosophila lifespan.
        
        
          Conclusions
          A system for conditional RNAi in Drosophila adults shows promise for assay of gene functions during aging. Our results indicate that Pgm does not have a simple strong effect on longevity.
Patent AT-E40013-T1: [Translated] FILM GUIDE AND PROJECTOR, CAMERA OR AE. DEVICE WITH SUCH FACILITIES.

A film support element assembly (20) is disclosed, primarily for supporting film (42) in relation to a projection aperture in a motion picture projector having a rolling loop film transport mechanism. In a preferred embodiment the film support element (44; 44') is a so-called «field flattener» and has a cylindrically curved surface over which successive frames in the film are laid by the mechanism. Cleaning means (52, 54; 154, 156; 186, 188; 220, 222; 234; 234<sub>'</sub>) are provided adjacent the film path and the lens element can be displaced to bring a fresh portion of the surface into the film path. At the same time, the cleaning means remove debris from the surface. In one embodiment the lens element (44<sub>'</sub>) is vibrated (234; 234') to discourage adhesion of debris.
2016-2018 NSDUH Substate Region Shapefile

This report provides a guide to the development and presentation of 2016-2018 NSDUH substate estimates. A summary of the estimation methodology is included as well as sample sizes, response rates, and population estimates. This shapefile includes geographic boundaries of the 2016-2018 NSDUH substate regions along with prevalence rates, map group values, and the upper and lower bounds found in the map legends. It can be used for analysis and data display with Geographic Information Systems (GIS) software.
USF2 inhibits C/EBP-mediated transcriptional regulation of the RIIβ subunit of cAMP-dependent protein kinase

Background
          Cyclic AMP-dependent protein kinase (PKA) plays a central role in regulation of energy metabolism. Upon stimulation of testicular Sertoli cells by follicle stimulating hormone (FSH), glycolysis is activated to increase the production of nutrients for the germ cells, and a new regulatory subunit of cAMP-dependent protein kinase, RIIβ, is induced. We have previously shown that production of the transcription factor C/EBPβ is rapidly increased by FSH and cAMP in primary Sertoli cell cultures, and that C/EBPβ induces the RIIβ promoter.
        
        
          Results
          In this work we show that USF1, USF2 and truncated USF isoforms bind to a conserved E-box in the RIIβ gene. Interestingly, overexpression of USF2, but not USF1, led to inhibition of both cAMP- and C/EBPβ-mediated induction of RIIβ. Furthermore, Western blots show that a novel USF1 isoform is induced by cAMP in Sertoli cells.
        
        
          Conclusions
          These results indicate that the expression of various USF isoforms may be regulated by cAMP, and that the interplay between USF and C/EBPβ is important for cAMP-mediated regulation of RIIβ expression. The counteracting effects of USF2 and C/EBPβ observed on the RIIβ promoter is in accordance with the hypothesis that C/EBP and USF play opposite roles in regulation of glucose metabolism.
Prevalence of Children with No Caries, Sealant or Restorations in Maryland School Children, 2005-2006

This is historical data. The update frequency has been set to "Static Data" and is here for historic value. Updated on 8/14/2024

This is the weighted prevalence of 1,276 schoolchildren.  1,276 out of 1,280 cases examined had prevalence available.  One out of 1,276 cases had grade information missed, 564 were in Kindergarten and 711 in 3rd grade.  Prevalence is defined as occurrence of no caries, sealants, or restorations among all selected population.  Region Identifiers and Constituent Counties:	 Western (Allegany, Frederick, Garrett, Washington); Central D.C. (Howard, Montgomery, Prince George’s); Southern (Calvert, Charles, St. Mary’s); Central Baltimore (Anne Arundel, Baltimore City, Baltimore County, Carroll, Harford); Eastern Shore (Caroline, Cecil, Dorchester, Kent, Queen Anne’s, Somerset, Talbot, Wicomico, Worcester).
Workers' compensation claims related to natural rubber latex gloves among Oregon healthcare employees from 1987–1998

Background
          Occupational reaction to natural rubber latex (NRL) glove use by healthcare employees has been an area of increasing concern. Unfortunately, there is little data demonstrating the prevalence and severity of actual reactivity to NRL.
        
        
          Method
          Occupational reaction to NRL was estimated using workers' compensation claims filed by healthcare employees in Oregon for the period of 1987–1998. For the first ten years, these claims were estimated by source and conditions consistent with NRL glove reactions, while in the last two years a specific code developed in 1997 for NRL glove reactions was also employed.
        
        
          Results
          The claim rate was on average 0.58 per 10,000 healthcare workers annually, which constituted 0.29% of all workers' compensation claims. The most common condition experienced was dermatitis (80%) and most common body part affected was the hands (55.4%). The majority of claimants, 45 (69.2%), reported taking less than a month off work, suggesting most reactions were minor in nature, although one fatality was reported. The average NRL claim cost was $8,309.48. Overall the average cost per insured healthcare worker was approximately $0.50 per year. The occupational groups with the highest number of claims were nurses (30.8% of claimants) and nursing aides and orderlies (24.6% of claimants).
        
        
          Conclusions
          In comparison with other workers' compensation claims filed by healthcare workers during this period, 0.25% of the total was potentially related to NRL gloves. The rare incidence of respiratory and ocular claims is inconsistent with the hypothesis that asthmatic or conjunctival reactions to NRL gloves are common.
New York City – 5 Boros: Drug-Related Emergency Department Visits, 2004-2011 - Illicits (excluding alcohol)

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving illicit drugs for New York City\'s 5 boroughs, covering 2004-2011. These visits involve the use of drugs that have limited or no therapeutic value and are generally illegal if taken without a prescription. It also includes visits involving the inhalation of substances for their psychoactive properties (e.g., sniffing model airplane glue).
Arrestee Substance Use: Comparison of Estimates from the National Survey on Drug Use and Health and the Arrestee Drug Abuse Monitoring Program

Abstract The National Survey on Drug Use and Health (NSDUH) and the Arrestee Drug Abuse Monitoring (ADAM) Program provide information on alcohol and drug use by individuals who have recently been arrested. The studies differ in their target populations (civilian, noninstitutionalized individuals vs. arrestees in 39 sites recently booked into jails) and data collection methods. This study uses 2003 ADAM and 2002–2008 NSDUH data for adult males living in the 39 ADAM sites who reported a past year arrest and 2002–2008 Uniform Crime Reporting (UCR) data to examine how well NSDUH covers the arrestee population and to compare estimates of drug and alcohol use and substance abuse or dependence. In general, ADAM estimates of rates of self-reported drug use were higher. The magnitude of these differences cannot be accounted for by undercoverage in NSDUH. Other possible reasons for these differences and their implications for interpreting NSDUH and ADAM data are discussed.
Size does matter: overcoming the adeno-associated virus packaging limit

Recombinant adeno-associated virus (rAAV) vectors mediate long-term gene transfer without any known toxicity. The primary limitation of rAAV has been the small size of the virion (20 nm), which only permits the packaging of 4.7 kilobases (kb) of exogenous DNA, including the promoter, the polyadenylation signal and any other enhancer elements that might be desired. Two recent reports (D Duan et al: Nat Med 2000, 6:595-598; Z Yan et al: Proc Natl Acad Sci USA 2000, 97:6716-6721) have exploited a unique feature of rAAV genomes, their ability to link together in doublets or strings, to bypass this size limitation. This technology could improve the chances for successful gene therapy of diseases like cystic fibrosis or Duchenne muscular dystrophy that lead to significant pulmonary morbidity.
Compound 527394: 1,4-Dimethyl-2-n-butylbenzene

Chemical compound data from PubChem database. IUPAC Name: 2-butyl-1,4-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Information Memorandum (IM-17-04)

This Information Memorandum (IM) supersedes ACYF-CB-IM-02-06 issued May 23, 2002 which addressed procedures for requesting extensions of child welfare waiver demonstrations. This IM alerts title IV-E agencies to updated and streamlined procedures that the Department of Health and Human Services will follow in considering requests to extend child welfare waiver demonstration projects approved under the authority of section 1130 of the Social Security Act.

Metadata-only record linking to the original dataset. Open original dataset below.
Weekly Cumulative Influenza Vaccine Doses Distributed in the United States

Weekly Cumulative Influenza Vaccine Doses Distributed in the United States, 2016-2021

• Flu vaccine is produced by private manufacturers. For the 2020-2021 season, manufacturers have projected they will provide as many as 194 to 198 million doses of influenza vaccine for the U.S. market.
• Additional information is available: https://www.cdc.gov/flu/prevent/vaccine-supply-distribution.htm.
Expression of a crown gall biological control phenotype in an avirulent strain of

Background
          Agrobacterium vitis is a causal agent of crown-gall disease. Trifolitoxin (TFX) is a peptide antibiotic active only against members of a specific group of α-proteobacteria that includes Agrobacterium and its close relatives. The ability of TFX production by an avirulent strain of Agrobacterium to reduce crown gall disease is examined here.
        
        
          Results
          TFX was shown to be inhibitory in vitro against several A. vitis strains. TFX production, expressed from the stable plasmid pT2TFXK, conferred biological control activity to an avirulent strain of A. vitis. F2/5, against three virulent, TFX-sensitive strains of A. vitis tested on Nicotiana glauca. F2/5(pT2TFXK) is significantly reduces number and size of galls when co-inoculated with tumorigenic strain CG78 at a 10:1 ratio, but is ineffective at 1:1 or 1:10 ratios. F2/5(pT2TFXK) is effective when co-inoculated with tumorigenic strain CG435 at 10:1 and 1:1 ratios, but not at a 1:10 ratio. When F2/5(pT2TFXK) is co-inoculated with CG49 at a 10:1 ratio, the incidence of gall formation does not decline but gall size decreases by more than 70%. A 24 h pre-inoculation with F2/5(pT2TFXK) does not improve biological control at the 1:10 ratio.
        
        
          Conclusions
          TFX production by an avirulent strain of Agrobacterium does confer in that strain the ability to control crown gall disease on Nicotiana glauca. This is the first demonstration that the production of a ribosomally synthesized, post-translationally modified peptide antibiotic can confer reduction in plant disease incidence from a bacterial pathogen.
Patent AT-E401367-T1: [Translated] WATER SOLUBLE FILM ARTICLE WITH A SALT LAYER AND PRODUCTION METHOD THEREOF

Water-soluble articles such as films, which can be made resistant to contact with small amounts of water, and methods of making the same are disclosed. The water-soluble article is formed from a water-soluble film-forming composition, such as polyvinyl alcohol, and includes a salt that is distributed more closely to at least one of the surfaces than throughout its thickness.
Compound 526321: 2,3,6-Tribromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,3,6-tribromodibenzofuran. Molecular Formula: C12H5Br3O. Molecular Weight: 404.88. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.