AndreaBozzo/ceres-open-data-index huggingface dataset:
Localities for 2015B

For January 1, 2015 through March 31, 2015, the PFS update was set at 0.0 percent by the Protecting Access to Medicare Act. After applying the budget neutrality adjustment of 0.9981, the conversion factor for January 1, 2015, through March 31, 2015 is $35.7547. Under the provisions of current law regarding the SGR, the conversion factor will change to $28.1872 on April 1, 2015 in the absence of Congressional action. In addition, the geographic practice cost index work floor of 1.0 expires on March 31, 2015 in the absence of legislative action.
Genetic stabilization by p53 involves growth regulatory and repair pathways

p53 performs a plethora of activities, which are directed towards
the maintenance of the genomic integrity and constitute its
universal role as a tumor suppressor. 1000 to 10000 latent p53
molecules are permanently available in order to monitor DNA
exchange processes in mitotically growing cells. After the
introduction of major DNA injuries the levels of
posttranslationally modified p53 proteins rise, which in turn
transcriptionally signal transient cell cycle arrest or apoptotic
cell death, depending on the extent of damage. Taken together,
p53 inhibits the manifestation of genomic instabilities at
different control levels both during naturally occurring metabolic
processes and in response to genotoxic treatments.
Compound 527441: 3-Mercapto-3-methylbutanal

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-3-sulfanylbutanal. Molecular Formula: C5H10OS. Molecular Weight: 118.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Table 25. Any Mental Illness in the Past Year among Persons Aged 18 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year any mental illness among those aged 18 or older by State and substate regions.
Cumulative Percentage of Children Ages 6 Months -17 Years Who Are Up to Date with the Updated 2023-24 COVID-19 Vaccine

• COVID-19 vaccination coverage among children 6 months to 17 years is assessed through the National Immunization Survey providing weekly COVID-19 vaccination coverage estimates (https://www.cdc.gov/vaccines/imz-managers/nis/about.html). 

• Weekly estimates of COVID-19 vaccination coverage and parental intent for vaccination among children through December 31, 2023, were calculated using data from the National Immunization Survey-Child COVID Module (NIS-CCM) (https://www.cdc.gov/vaccines/imz-managers/nis/about.html#nis-ccm). Beginning January 2, 2024, the NIS-CCM was discontinued, and questions regarding receipt of COVID-19 vaccination among children were added to the NIS-Flu (https://www.cdc.gov/vaccines/imz-managers/nis/about.html#nis-cim). 

• Starting in September 2023, the CDC recommended the 2023-2024 updated COVID-19 vaccine to protect against serious illness from COVID-19 (https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html).
Laser-induced breakdown spectroscopy: a tool for real-time,

Background
          Laser Induced Breakdown Spectroscopy (LIBS) can be used to measure trace element concentrations in solids, liquids and gases, with spatial resolution and absolute quantifaction being feasible, down to parts-per-million concentration levels. Some applications of LIBS do not necessarily require exact, quantitative measurements. These include applications in dentistry, which are of a more "identify-and-sort" nature – e.g. identification of teeth affected by caries.
        
        
          Methods
          A one-fibre light delivery / collection assembly for LIBS analysis was used, which in principle lends itself for routine in vitro / in vivo applications in a dental practice. A number of evaluation algorithms for LIBS data can be used to assess the similarity of a spectrum, measured at specific sample locations, with a training set of reference spectra. Here, the description has been restricted to one pattern recognition algorithm, namely the so-called Mahalanobis Distance method.
        
        
          Results
          The plasma created when the laser pulse ablates the sample (in vitro / in vivo), was spectrally analysed. We demonstrated that, using the Mahalanobis Distance pattern recognition algorithm, we could unambiguously determine the identity of an "unknown" tooth sample in real time. Based on single spectra obtained from the sample, the transition from caries-affected to healthy tooth material could be distinguished, with high spatial resolution.
        
        
          Conclusions
          The combination of LIBS and pattern recognition algorithms provides a potentially useful tool for dentists for fast material identification problems, such as for example the precise control of the laser drilling / cleaning process.
Chicago: Drug-Related Emergency Department Visits, 2004-2011 - Illicits (excluding alcohol)

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving illicit drugs for the Chicago metropolitan area, covering 2004-2011. These visits involve the use of drugs that have limited or no therapeutic value and are generally illegal if taken without a prescription. It also includes visits involving the inhalation of substances for their psychoactive properties (e.g., sniffing model airplane glue).
Compound 528114: 2-Chloro-5-isopropyl-3-methylpyrazine

Chemical compound data from PubChem database. IUPAC Name: 2-chloro-3-methyl-5-propan-2-ylpyrazine. Molecular Formula: C8H11ClN2. Molecular Weight: 170.64. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
A new automated method for the determination of the Total Antioxidant Capacity (TAC) of human plasma, based on the crocin bleaching assay

Background
          Antioxidant molecules, which scavenge free radical species to prevent or delay oxidative damage of important macromolecules, membrane lipids and lipoproteins, are prevalent in plasma and other biological fluids. Among them, bilirubin, uric acid and protein thiols are the major endogenous antioxidants, while vitamins C and E, as well as a number of food-derived (poly)aromatic substances, belonging to stilbens, flavonoids and phenolic acids, are the main classes of nutritional antioxidants. Assays for total antioxidant capacity in plasma differ in their type of oxidation source, target and measurement used to detect the oxidized product.
        
        
          Methods
          In the present work we present an automated assay for the estimation of blood total antioxidant capacity (TAC assay), based on the crocin bleaching (oxidation) method. This method was adapted on a modern autoanalyzer, was linear over a wide range of values (0–3 mmol/L), and performed using an end point measurement.
        
        
          Results
          The TAC method presented a linear correlation with another automated commercial Total Antioxidant Status (TAS) test. Detection of the interference of different metabolites revealed a significant participation of TAC from uric acid, bilirubin, albumin, a minor interference from ascorbic acid, and no interference from hemoglobin. TAC was not modified by two freeze/thawing cycles, and was stable in samples stored at room temperature for 4 hours. K-EDTA and heparin were the best anticoagulants, while citrate decreased TAC by 20%. Reference values derived from samples of normal blood donors was 1.175 ± 0.007 mmol/L (mean ± SEM), while a diet rich in antioxidants more than doubled this value.
        
        
          Conclusions
          The proposed TAC assay, is fully automated, stable and reliable, and could be of value in the estimation of the AC of plasma. It is further proposed to calculate the antioxidant capacity of plasma after a subtraction of all interference deriving from endogenous and/or exogenous metabolites. The antioxidant capacity of plasma thus calculated can be used as a useful indicator of the antioxidant value of foods and beverages in the daily diet.
Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients

Background
          Red blood cell (RBC) transfusion is commonly used to increase oxygen transport in patients with sepsis. However it does not consistently increase oxygen uptake at either the whole-body level, as calculated by the Fick method, or within individual organs, as assessed by gastric intra-mucosal pH.
        
        
          Aim
          This study evaluates the hemodynamic and oxygen utilization effects of hemoglobin infusion on critically ill septic patients.
        
        
          Methods
          Fifteen septic patients undergoing mechanical ventilation whose hemoglobin was <10 g% were eligible. Ten patients (APACHE II: 25.5 ± 7.6) received an infusion of 1 unit of packed RBC over 1 h while sedated and paralyzed. The remaining five control patients (APACHE II: 24.3 ± 6.0) received a 5% albumin solution (500 ml) over 1 h. Hemodynamic data, gastric tonometry and calorimetry were obtained prior to and immediately after RBC transfusion or 5% albumin infusion.
        
        
          Results
          Transfusion of RBC was associated with an improvement in left ventricular systolic work index (38.6 ± 12.6 to 41.1 ± 13.0 g/min/m2; P = 0.04). In the control group there was no significant change in the left ventricular systolic work index (37.2 ± 14.3 to 42.2 ± 18.9 g/min/m2). An increase in pulmonary vascular resistance index (203 ± 58 to 238 ± 49 dyne/cm5/m2; P = 0.04) was also observed, while no change was produced by colloid infusion (237 ± 87.8 to 226.4 ± 57.8 dyne/cm5/m2). Oxygen utilization did not increase either by Fick equation or by indirect calorimetry in either group. Gastric intramucosal pH increased only in the control group but did not reach statistical significance.
        
        
          Conclusion
          Hemoglobin increase does not improve either global or regional oxygen utilization in anemic septic patients. Furthermore, RBC transfusion may hamper right ventricular ejection by increasing the pulmonary vascular resistance index.
Compound 528576: (1,1-Dimethylethyl)dimethylsilyl 2-(((1,1-dimethylethyl)dimethylsilyl)oxy)acetate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[tert-butyl(dimethyl)silyl]oxyacetate. Molecular Formula: C14H32O3Si2. Molecular Weight: 304.57. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528104: 2,2,2-Trichloroethyl 2,3,4,5,6-pentafluorobenzoate

Chemical compound data from PubChem database. IUPAC Name: 2,2,2-trichloroethyl 2,3,4,5,6-pentafluorobenzoate. Molecular Formula: C9H2Cl3F5O2. Molecular Weight: 343.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E39995-T1: [Translated] COMPRESSED AIR DELIVERY AND DOSING DEVICE.

1. Method of fluidizing and blowing-in coal dust with compressed air into the conveying and metering line of a cupola furnace, wherein the material to be conveyed is fluidized in the vessel and is blown by means of nozzles out of the fluidized zone intermittently into the conveying and metering line, characterized in that, between the conveying intervals, only pressurized air is blown into the conveying and metering line (016).
The DAWN Report: Emergency Department Visits Involving Buprenorphine

This Drug Abuse Warning Network (DAWN) short report shows the estimated number of emergency room visits involving buprenorphine between 2005 and 2011. Buprenorphine is used to treat dependence on heroin and narcotic pain medications. The report also shows buprenorphine-related visits broken out by non-medical use, adverse reactions and seeking detoxification or treatment. The report talks about emergency room visits for buprenorphine alone and in combination with other drugs such as marijuana, cocaine, heroin and benzodiazepines.
Patent AT-E400322-T1: [Translated] DYE FOR KERATIN FIBERS CONTAINING N-(2-HYDROXYBENZENE) CARBAMAT OR N-(2-HYDROXYBENZENE) UREA DERIVATIVES AS COUPLERS AND DYEING PROCESSES

Composition (A) for oxidation dyeing of keratin fibers comprises at least one oxidation base (II) and, as coupler, at least one N-(2-hydroxyphenyl)-carbamate or -urea derivative (I), or their acid addition salts. The couplers are of formula (I); R1 = hydrogen or a 1-15C linear or branched group (the branches may form one or more carbocyclic rings with 3-7 members), optionally containing one or more multiple bonds (optionally forming aromatic groups) and with one or more carbons replaced by oxygen, nitrogen, sulfur or sulfonyl, and the carbon atoms are optionally independently substituted by one or more halo, provided that a sulfonyl is not attached to the nitrogen atom shown and that R1 does not contain a peroxide bond nor diazo, nitro or nitroso group; X = OR5 or NR6R7; R groups = variously hydrogen, substituents or together form rings, subject to certain provisos; Y = hydrogen, halo, OR8, SR8 or NHSO2R8; R8 = 1-8C linear or branched alkyl (branches may form one or more rings of 3-6 members), optionally substituted by one or more of halo, hydroxy, 1-4C alkoxy, amino or 1-4C alkylamino; phenyl (optionally substituted by one or two of 1-4C alkyl or alkoxy, trifluoromethyl, carboxy, 1-4C alkoxycarbonyl, halo, hydroxy, amino or 1-4C alkylamino) or benzyl. The full definitions are given in the DEFINITIONS (Full Definitions) Field. Independent claims are also included for: (a) method for dyeing keratin fibers, especially human hair, by application of (A) and development of color with an oxidizing agent; and (b) dyeing kit containing, in separate containers, (A) and the oxidizing agent.
Compound 528991: Heneicosane, 1,2-bis(methylthio)

Chemical compound data from PubChem database. IUPAC Name: 1,2-bis(methylsulfanyl)henicosane. Molecular Formula: C23H48S2. Molecular Weight: 388.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529375: Tyr isoBOC TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-(2-methylpropoxycarbonylamino)-3-[4-(2-methylpropoxycarbonyloxy)phenyl]propanoate. Molecular Formula: C25H41NO7Si. Molecular Weight: 495.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Survey of Early Care and Education 2019

The 2019 National Survey of Early Care and Education (2019 NSECE) is a set of four nationally-representative integrated surveys conducted in 2019 of 1) households with children under age 13, 2) home-based early care and education (ECE) providers, 3) center-based ECE providers, and 4) the center-based ECE provider workforce. Together these four surveys characterize the supply of and demand for ECE in the United States and create a better understanding of how well families' needs and preferences coordinate with providers' offerings and constraints. The NSECE surveys make particular effort to measure the experiences of low-income families, as these families are the focus of a significant component of ECE and school-age public policy.

The NSECE was first conducted in 2012. Before that effort, there had been a 20-year long absence of nationally representative data on the use and availability of ECE. The NSECE was conducted again in 2019 to update the information from 2012 and shed light on how the ECE and school-age care landscape changed from 2012 to 2019. The 2019 NSECE followed a similar design as the 2012 survey, including surveying households with children under age 13, home-based providers, center-based providers, and staff working in center-based classrooms.

<b>Units of Response: </b>Households, Early Care and Education Providers, early childhood workforce

<b>Type of Data: </b>Survey

<b>Tribal Data: </b>No

<b>Periodicity: </b>Irregular

<b>Demographic Indicators: </b>Disability;Ethnicity;Geographic Areas;Household Income;Housing Status;Indigenous Population;Military;Race;Sex

<b>SORN: </b>https://www.federalregister.gov/documents/2022/09/19/2022-20139/privacy-act-of-1974-system-of-records

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>https://www.childandfamilydataarchive.org/cfda/archives/cfda/studies/37941/datadocumentation

<b>Granularity: </b>Childcare Providers;Classroom;Family;Household;Individual;Nation;State

<b>Spatial: </b>United States

<b>Geocoding: </b>Not Applicable
Compound 528797: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26-Hexacosamethylcyclotridecasiloxane

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26-hexacosamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25-tridecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26-tridecasilacyclohexacosane. Molecular Formula: C26H78O13Si13. Molecular Weight: 964.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527677: Butanoic acid, 2-chloro, 1-methylpropyl ester

Chemical compound data from PubChem database. IUPAC Name: butan-2-yl 2-chlorobutanoate. Molecular Formula: C8H15ClO2. Molecular Weight: 178.65. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527831: N-alpha-Acetyl lysine, butyl ester

Chemical compound data from PubChem database. IUPAC Name: butyl 2-acetamido-6-aminohexanoate. Molecular Formula: C12H24N2O3. Molecular Weight: 244.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Publications Using SAMHSA DataSeattle: Drug-Related Emergency Department Visits, 2004-2011 - Adverse Reactions

Excel file with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving adverse reactions in the Seattle metropolitan area. It includes ED visits in which an adverse health consequence (e.g., side effects or an allergic reaction) resulted when taking prescription drugs, over-the-counter medications, or dietary supplements as prescribed or recommended.  This analytic category does not include drug misuse or abuse.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.
Compound 528152: alpha,alpha-Diphenyl-2-piperidinepropanol

Chemical compound data from PubChem database. IUPAC Name: 1,1-diphenyl-3-piperidin-2-ylpropan-1-ol. Molecular Formula: C20H25NO. Molecular Weight: 295.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401685-T1: [Translated] HOLLOW OPTICAL FIBER

The invention relates to optical fibers incorporating cavities in their structure. This is an optical fiber comprising: a central core (1); a first annular region (ra) surrounding the central core (1); a second annular region (rb) surrounding the first annular region (ra) and comprising medium-size cavities (3) the cross section whereof remains strictly between a given first threshold and a given second threshold strictly higher than the first threshold; a third annular region (rc) surrounding the second annular region (rb) and comprising large cavities (4) the cross section whereof remains strictly above the second threshold; in a cross section of the optical fiber, any radius that goes from the center of the core towards the exterior of the optical fiber encounters at least either a medium-size cavity (3) in the second annular region (rb) or a large cavity (4) in the third annular region (rc); and the average distance between the outer perimeter (Ca) of the second annular region (rb) and the inner perimeter (Cb) of the third annular region (rc) is less than half the average dimension of a large cavity (4).
Compound 527100: Fluvoxamine, acetyl

Chemical compound data from PubChem database. IUPAC Name: N-[2-[[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethyl]acetamide. Molecular Formula: C17H23F3N2O3. Molecular Weight: 360.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
North Carolina: 2011-2012 NSDUH

This report presents North Carolina\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 529362: Gly isoBOC TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-(2-methylpropoxycarbonylamino)acetate. Molecular Formula: C13H27NO4Si. Molecular Weight: 289.44. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.