AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E400227-T1: [Translated] DEVICE FOR OSTEOSYNTHESIS

Osteosynthesis device, particularly for the spine by means of internal implantation, comprising firstly one or more bars (2) used to support or move the spine, and secondly at least one implant (3) connecting the bars and the vertebrae, said implant comprising firstly bone anchorage means attached to the body of said implant and secondly fixation means for said bars, said fixation being carried out by clamping means (31) clamping said bar against the internal walls (320) of a channel (32), with an opening, formed in said body of the implant (3), characterised in that said bars comprise a transversal bearing surface (21) on at least part of their length, said transversal bearing surface being produced by a cross-section of said bars comprising at least one part of lower or opposed convexity in relation to the rest of said cross-section, and in that the axis of the clamping means is merged with or parallel to the symmetrical axis of the bone anchorage means of the body, and the clamping means comprise a surface (310) which is adapted to the transversal bearing surface (21) of the bar (2),the contact surface, between the bar and surface (310) of the clamping means or the internal wall (320) of the channel (32), being adapted to allow to carry out a rotation or transversal shift of the bar to adjust the transversal position and the angular position of this bar on the body.
Compound 528839: Glycerol, 2,3-dimethyl, 1-(14-methylpentadecanoate)

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethoxypropyl 14-methylpentadecanoate. Molecular Formula: C21H42O4. Molecular Weight: 358.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529447: Phenanthrene, 9,10-dihydro, 1,10-propano

Chemical compound data from PubChem database. IUPAC Name: 5,6,6a,7-tetrahydro-4H-benzo[a]phenalene. Molecular Formula: C17H16. Molecular Weight: 220.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527717: Isobutyl 2,3-dichloropropanoate

Chemical compound data from PubChem database. IUPAC Name: 2-methylpropyl 2,3-dichloropropanoate. Molecular Formula: C7H12Cl2O2. Molecular Weight: 199.07. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Face mask fit modifications that improve source control performance dataset

SARS-CoV-2 is a highly infectious respiratory virus that is primarily transmitted by respiratory aerosols and droplets emitted during activities such as talking, breathing, and coughing.  Because symptomatic and asymptomatic individuals with COVID-19 can exhibit a high viral load of SARS-CoV-2 in their respiratory fluids, the CDC recommends that people wear a face mask that covers the nose and mouth to reduce community transmission during the COVID-19 pandemic. Wearing a face mask to protect others from potentially infectious droplets, called source control, has been shown to be a highly effective infection control strategy to limit the spread of COVID-19.  The presence of mask face seal leaks enables respiratory aerosols to escape out rather than pass through the filtering materials of the mask, consequently reducing the benefits of wearing a face mask for source control.  As such, the current investigation examines various modifications that improve the fit of a medical or cloth face mask and reduce the amounts of expelled aerosols during simulated coughs and exhalations.
Program Instruction (PI-18-06)

This Program Instruction (PI) provides guidance to states, territories, and insular areas (hereafter "states," unless otherwise noted) administering titles IV-B and IV-E of the Act and the Child Abuse Prevention and Treatment Act (CAPTA) and to Indian Tribes, Indian Tribal Organizations, or Indian Tribal Consortia (hereafter "tribes" unless otherwise noted) administering titles IV-B and IV-E of the Act of changes in law and funding affecting the information that must be submitted with the Annual Progress and Services Report due June 30, 2018.

Metadata-only record linking to the original dataset. Open original dataset below.
Miami - Dade Div: Drug-Related Emergency Department Visits, 2004-2011 - Suicide Attempts

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving suicide attempts in the Dade division of the Miami metropolitan area, covering 2004-2011.  Drug-related suicide attempts include visits for drug overdoses and for suicide attempts by other means (e.g., using a firearm) if drugs were involved or related to the suicide attempt.
Compound 528790: Cyclopentatricontasiloxane, heptacontamethyl

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36,38,38,40,40,42,42,44,44,46,46,48,48,50,50,52,52,54,54,56,56,58,58,60,60,62,62,64,64,66,66,68,68,70,70-heptacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59,61,63,65,67,69-pentatriacontaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70-pentatriacontasilacycloheptacontane. Molecular Formula: C70H210O35Si35. Molecular Weight: 2595.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2013 NSDUH Trend Tables  (Prevalence Estimates) - 7.1 to 7.45

These detailed tables show trends in population totals and prevalence estimates of illicit drug use, risk and protective factors, substance initiation, substance dependence/abuse, and need/receipt of substance use treatment from the 2013 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens (including LSD, PCP, Ecstasy, Ketamine, DMT/AMT/Foxy, Salvia divinorum), inhalants, and the nonmedical use of prescription-type pain relievers (including OxyContin), tranquilizers, stimulants (Adderall) , sedatives (GHB, Ambien), non-prescription cold medicine, alcohol, and tobacco products (including cigarettes, smokeless tobacco, cigars, pipes). Results are provided for lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area. Comparisons are made between 2013 and 2002 through 2012.
Compound 528591: tert-Butyl(dimethyl)silyl phenylacetate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-phenylacetate. Molecular Formula: C14H22O2Si. Molecular Weight: 250.41. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400769-T1: [Translated] LOW STRETCH DRIVE BELT

A power transmission belt, and more particularly a toothed power transmission belt, comprising a longitudinally extending tensile member composed of one or more carbon fiber cords, wherein the cords are treated with an elastomer latex coating, and that the cord treatment composition further comprises a resorcinol-formaldehyde reaction product, and that such cord treatment composition possesses an elastic modulus at a temperature of 20° C. to be within the range of from about 1.0x10<7 >dynes/cm<2 >to about 5.0x10<8 >dynes/cm<2>, and at a temperature of 100° C. to be within the range of from about 5.0x10<8 >dynes/cm<2 >to about 4.0x10<8 >dynes/cm<2>.
Patent AT-E40177-T1: [Translated] ANCHORING ELEMENT FOR MOUNTING CLIMBING DEVICES IN WALL SURFACES.

1. Step iron anchor element which can be fastened in wall surfaces (34) and has an internal reinforcement (5) of metal, with at least one insert end (5a) and an anchor sleeve (7) of plastic which sits firmly on the insert end, said anchor sleeve having a frontal terminating cone (8), a central anchoring portion (10) which is a continuation of the terminating cone and is provided with transverse ribs (9), an elastic sealing collar (11) being arranged to be freely displaceable on the end of said anchor sleeve that is opposite the terminating cone (8), characterised in that a) the end of the anchor sleeve (7) is provided with a series of adjacent, continuously encircling annular ribs (13, 18) and annular grooves which form retention members, and b) the sealing collar (11) is a flexible elastomer collar which fits snugly on the annular ribs (13, 18) and on its inside face likewise has a series of annular ribs (15) which cooperate elastically with the annular ribs (13, 18) of the anchor sleeve (7) to form a sealing system of teeth.
Washington: 2011-2012 NSDUH

This report presents Washington\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Weekly Cumulative RSV Vaccination Coverage and Intent, Overall, by Selected Demographics and Jurisdiction, Among Adults 75 and Older and 50-74 Years with High-Risk Conditions Ever Vaccinated, United States

• Weekly Cumulative RSV Vaccination Coverage and Intent Among Adults 75 Years and Older and 50-74 Years with High Risk Conditions Ever Vaccinated with RSV Vaccine by Demographic Characteristics and Jurisdiction 

• Weekly estimates of RSV vaccination coverage and intent among adults 75 years and older and 50-74 years with high risk conditions are calculated using data from National Immunization Surveys (NIS) – Fall Respiratory Virus Module (NIS–FRVM) https://www.cdc.gov/nis/about/index.html. The NIS-FRVM is an ongoing random-digit-dial cellular telephone survey of households with adults 18 years and older.  

• In June 2025, the Advisory Committee on Immunization Practices (ACIP) voted to recommend that adults aged 50–74 years who are at increased risk for severe RSV disease may receive a single dose of an RSV vaccine. In June 2024, the ACIP voted to recommend a single dose of RSV vaccine for all adults 75 years and older. The data below capture ever receiving a dose of an RSV vaccine by adults 50 years and older. 
 
• The NIS-FRVM data posted on the dashboard below are currently a few days behind the data that are posted on the Respiratory Illnesses Data Channel (https://www.cdc.gov/respiratory-viruses/data/index.html). This lag is due to the time it takes to review data by geographic and sociodemographic characteristics and summarize the findings.
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overload

Background
          Icodextrin is a high molecular weight, starch-derived glucose polymer, which is capable of inducing sustained ultrafiltration over prolonged (12–16 hour) peritoneal dialysis (PD) dwells. The aim of this study was to evaluate the ability of icodextrin to alleviate refractory, symptomatic fluid overload and prolong technique survival in PD patients.
        
        
          Methods
          A prospective, open-label, pre-test/post-test study was conducted in 17 PD patients (8 females/9 males, mean age 56.8 ± 2.9 years) who were on the verge of being transferred to haemodialysis because of symptomatic fluid retention that was refractory to fluid restriction, loop diuretic therapy, hypertonic glucose exchanges and dwell time optimisation. One icodextrin exchange (2.5 L 7.5%, 12-hour dwell) was substituted for a long-dwell glucose exchange each day.
        
        
          Results
          Icodextrin significantly increased peritoneal ultrafiltration (885 ± 210 ml to 1454 ± 215 ml, p < 0.05) and reduced mean arterial pressure (106 ± 4 to 96 ± 4 mmHg, p < 0.05), but did not affect weight, plasma albumin concentration, haemoglobin levels or dialysate:plasma creatinine ratio. Diabetic patients (n = 12) also experienced improved glycaemic control (haemoglobin Alc decreased from 8.9 ± 0.7% to 7.9 ± 0.7%, p < 0.05). Overall PD technique survival was prolonged by a mean of 11.6 months (95% CI 6.0–17.3 months). On multivariate Cox proportional hazards analysis, extension of technique survival by icodextrin was only significantly predicted by baseline net daily peritoneal ultrafiltration (adjusted HR 2.52, 95% CI 1.13–5.62, p < 0.05).
        
        
          Conclusions
          Icodextrin significantly improved peritoneal ultrafiltration and extended technique survival in PD patients with symptomatic fluid overload, especially those who had substantially impaired peritoneal ultrafiltration.
Table 8. Nonmedical Use of Pain Relievers in the Past Year, by Age Group and State: Percentages, Annual Averages Based on 2010 and 2011 NSDUHs

This report presents State estimates for measures of past year non-medical use of pain relievers based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Resuts are provided by age group.
PLACES: ZCTA Data (GIS Friendly Format), 2023 release

This dataset contains model-based ZIP Code Tabulation Area (ZCTA) level estimates in GIS-friendly format. PLACES covers the entire United States—50 states and the District of Columbia—at county, place, census tract, and ZIP Code Tabulation Area levels. It provides information uniformly on this large scale for local areas at four geographic levels. Estimates were provided by the Centers for Disease Control and Prevention (CDC), Division of Population Health, Epidemiology and Surveillance Branch. PLACES was funded by the Robert Wood Johnson Foundation in conjunction with the CDC Foundation. Data sources used to generate these model-based estimates are Behavioral Risk Factor Surveillance System (BRFSS) 2021 or 2020 data, Census Bureau 2010 population estimates, and American Community Survey (ACS) 2015–2019 estimates. The 2023 release uses 2021 BRFSS data for 29 measures and 2020 BRFSS data for 7 measures (all teeth lost, dental visits, mammograms, cervical cancer screening, colorectal cancer screening, core preventive services among older adults, and sleeping less than 7 hours) that the survey collects data on every other year. These data can be joined with the census 2010 ZCTA boundary file in a GIS system to produce maps for 36 measures at the ZCTA level. An ArcGIS Online feature service is also available for users to make maps online or to add data to desktop GIS software.
https://cdcarcgis.maps.arcgis.com/home/item.html?id=2c3deb0c05a748b391ea8c9cf9903588
Compound 527114: 1-Butanamine, 3-methyl, N-(1-methylethyl)

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-N-propan-2-ylbutan-1-amine. Molecular Formula: C8H19N. Molecular Weight: 129.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400292-T1: [Translated] USE OF LEPTIN IN INFERTILITY

Chemical patent from PubChem database. Patent Number: AT-E400292-T1. Title: Polymorphic Forms of Active Compounds. Filing Date: 2000-06-09. Inventors: Smith, John A., Johnson, Mary B.. Abstract: The invention describes polymorphic forms of active pharmaceutical compounds, each characterized by distinct crystallographic and thermal properties. IPC Classifications: C07H, A61K, A61P. This patent covers 36 claims related to 7 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Patent AT-E401593-T1: [Translated] CONTACT LENS MANUFACTURING

A method for controlling a production line for the manufacture and/or packaging of contact lenses which production line simultaneous by processes at least two lots, the method comprising dividing at least a portion of the production line into a series of cells through which the contact lens pass sequentially, and providing a control system comprising at least three shifts registers each containing information about each of said cells, including: (a) a location shift register which indicates whether a cell should be empty or occupied, (b) a lot data shift register which is a non-binary shift register and contains manufacturing and/or prescription data about the contact lens which should be in the cell and (c) a condition shift register which provides an indication of the condition of the product in the cell, and simultaneously indexing all of said shift registers as a lens passes down the production line from one cell to the next cell.
2013 NSDUH Sample Design Report

The respondent universe for the 2013 National Survey on Drug Use and Health (NSDUH) was the civilian, noninstitutionalized population aged 12 years or older residing within the 50 States and the District of Columbia. Consistent with the NSDUH designs since 1991, the 2013 NSDUH universe included residents of noninstitutional group quarters (e.g., shelters, rooming houses, dormitories, and group homes), residents of Alaska and Hawaii, and civilians residing on military bases. Coverage before the 1991 survey was limited to residents of the coterminous 48 States, and it excluded residents of group quarters and all persons (including civilians) living on military bases. Persons excluded from the 2013 universe included those with no fixed household address (e.g., homeless and/or transient persons not in shelters), the active military, and residents of institutional group quarters, such as jails and hospitals.
Compound 526249: 1,2,6,9-Tetrabromo-3,7-dichloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 1,2,6,9-tetrabromo-3,7-dichlorodibenzo-p-dioxin. Molecular Formula: C12H2Br4Cl2O2. Molecular Weight: 568.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526069: 1-Eicosanol, 18-methyl, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(18-methylhenicosoxy)silane. Molecular Formula: C25H54OSi. Molecular Weight: 398.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526744: 2-Nonyloxyethanol, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(2-nonoxyethoxy)silane. Molecular Formula: C14H32O2Si. Molecular Weight: 260.49. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Joint disease caused by defective gp130-mediated STAT signaling

IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling is mediated exclusively by the common signal-transducing component gp130, which is also essential for signal transduction of other cytokines of the leukemia inhibitory factor (LIF)/IL-6 family. M Ernst and colleagues generated and studied knock-in mice (gp130ΔSTAT/ΔSTAT), in which all STAT-binding sites (sites binding signal transducers and activators of transcription) were deleted from their gene encoding gp130 but binding sites for both Janus kinases (JAKs) and for the protein tyrosine phosphatase-2 (SHP-2) were preserved. They found that this mutant mouse displayed a blastocyst implantation defect, gastrointestinal ulceration, and, interestingly, severe joint disease with representative features of rheumatoid arthritis. Synovial cells from this mouse exhibited mitogenic hyper-responsiveness to cytokines of the LIF/IL-6 family, a phenomenon that was caused by sustained gp130-mediated SHP-2/Ras/Erk activation due to a defect in the induction of SOCS-1 (suppressor of cytokine signaling-1; also known as SSI or JAB). This suppressor, induced by STAT signaling, regulates cytokine signaling. It is, therefore, conceivable that the disturbance of the balanced activation between the STAT and SHP-2/Ras/Erk signal pathways causes the joint disease in the gp130ΔSTAT/ΔSTAT mouse. These findings may be beneficial in the elucidation of the cause and the treatment of rheumatoid arthritis in humans.
Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

Background
          Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its efficacy on non-nuclear genes and its effect on the interferon pathway remain unexplored. Since directed mutation of RNA genomes is not possible through conventional mutagenesis, we have tested sequence-specific 21-nucleotide long double-stranded RNAs (dsRNAs) for their ability to silence cytoplasmic RNA genomes.
        
        
          Results
          Short dsRNAs were generated against specific mRNAs of respiratory syncytial virus, a nonsegmented negative-stranded RNA virus with a cytoplasmic life cycle. At nanomolar concentrations, the dsRNAs specifically abrogated expression of the corresponding viral proteins, and produced the expected mutant phenotype ex vivo. The dsRNAs did not induce an interferon response, and did not inhibit cellular gene expression. The ablation of the viral proteins correlated with the loss of the specific mRNAs. In contrast, viral genomic and antigenomic RNA, which are encapsidated, were not directly affected.
        
        
          Conclusions
          Synthetic inhibitory dsRNAs are effective in specific silencing of RNA genomes that are exclusively cytoplasmic and transcribed by RNA-dependent RNA polymerases. RNA-directed RNA gene silencing does not require cloning, expression, and mutagenesis of viral cDNA, and thus, will allow the generation of phenotypic null mutants of specific RNA viral genes under normal infection conditions and at any point in the infection cycle. This will, for the first time, permit functional genomic studies, attenuated infections, reverse genetic analysis, and studies of host-virus signaling pathways using a wild type RNA virus, unencumbered by any superinfecting virus.
Compound 526260: 1,2,9-Tribromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,9-tribromodibenzofuran. Molecular Formula: C12H5Br3O. Molecular Weight: 404.88. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527103: 5-Methoxy-4'-(trifluoromethyl)valerophenone

Chemical compound data from PubChem database. IUPAC Name: 5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one. Molecular Formula: C13H15F3O2. Molecular Weight: 260.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.