AndreaBozzo/ceres-open-data-index huggingface dataset:
Triamcinolone acetonide

Triamcinolone Acetonide is a prescription topical ointment containing a corticosteroid that helps reduce inflammation and itching in various skin conditions. Available in strengths of 0.025%, 0.1%, and 0.5%, it's manufactured by E. Fougera & Co. and applied directly to the skin. This information was generated using AI and is provided for informational and research purposes only.
Compound 529062: Methyl 1-methylpyrrolidine-2-carboxylate

Chemical compound data from PubChem database. IUPAC Name: methyl 1-methylpyrrolidine-2-carboxylate. Molecular Formula: C7H13NO2. Molecular Weight: 143.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528947: Phenol, 2-(1-ethylbutyl)-4-nitro

Chemical compound data from PubChem database. IUPAC Name: 2-hexan-3-yl-4-nitrophenol. Molecular Formula: C12H17NO3. Molecular Weight: 223.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529178: 1-Pentanol, 5-amino, O,N,N-tris-TMS

Chemical compound data from PubChem database. IUPAC Name: N,N-bis(trimethylsilyl)-5-trimethylsilyloxypentan-1-amine. Molecular Formula: C14H37NOSi3. Molecular Weight: 319.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Cell-cell interactions in synovitis: Endothelial cells and immune cell migration

Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of endothelial cells in leukocyte extravasation will be discussed, including the role of the most relevant cellular adhesion molecules. These molecules play an important role in mediating leukocyte-endothelial interactions. It is likely that different adhesive pathways are involved in different steps of leukocyte adhesion to and migration through endothelia. Targeting of pathological endothelial function, including leukocyte-endothelial adhesion, may be useful for the future management of inflammatory arthritis.
NNDSS - TABLE 1CC. Rabies, Animal to Rabies, Human

NNDSS - TABLE 1CC. Rabies, Animal to Rabies, Human - 2019. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents. 

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published — CDC does not have data because of changes in how conditions are categorized.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2018 and 2019 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the US, a US territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-US Residents' category. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf. 
† Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
2013 CMHS Uniform Reporting System (URS) Tables for Guam

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Guam for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 527025: Octadecahydronaphthacene

Chemical compound data from PubChem database. IUPAC Name: 1,2,3,4,4a,5,5a,6,6a,7,8,9,10,10a,11,11a,12,12a-octadecahydrotetracene. Molecular Formula: C18H30. Molecular Weight: 246.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NSDUH 2020 Field Interviewer Manual

This detailed manual was used as a training guide for the Field Interviewers (FIs) who conducted the in-person 2020 National Survey on Drug Use and Health (NSDUH). It covers the information presented at the intensive training for new FIs. Although it is written for NSDUH FIs, researchers may find it helpful for learning about data collection challenges that could affect data quality. It also may be helpful for those designing their own field operations.The manual includes:An introduction to the survey;A guide to what is expected of FIs;Copies of materials that were mailed or given to respondents;FI instructions for locating sample dwelling units, contacting residents, obtaining participation, conducting the screening and interview, documenting their experiences; andQuality control and administrative procedures for FIs.
5.3 Clients in treatment, according to substance abuse problem and diagnosed co-occurring mental disorders, by facility operation and primary focus of facility: March 31, 2011. Number and percent

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing clients in treatment, according to substance abuse problem and diagnosed co-occurring mental disorders, by facility operation and primary focus of facility in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.
Compound 526672: Cholan-24-oic acid, 3,12-bis[(trimethylsilyl)oxy]-, methyl ester, (3alpha,5beta,12alpha)-

Chemical compound data from PubChem database. IUPAC Name: methyl 4-[10,13-dimethyl-3,12-bis(trimethylsilyloxy)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Molecular Formula: C31H58O4Si2. Molecular Weight: 551.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526572: 2,10,16-Trimethyltetratriacontane

Chemical compound data from PubChem database. IUPAC Name: 2,10,16-trimethyltetratriacontane. Molecular Formula: C37H76. Molecular Weight: 521.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525890: N,N-Dimethyl-N'-(4-methylphenyl)-isobutyramidine

Chemical compound data from PubChem database. IUPAC Name: N,N,2-trimethyl-N'-(4-methylphenyl)propanimidamide. Molecular Formula: C13H20N2. Molecular Weight: 204.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530221: Phenyllactic acid, 4-methoxy, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 3-(4-methoxyphenyl)-2-trimethylsilyloxypropanoate. Molecular Formula: C16H28O4Si2. Molecular Weight: 340.56. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528303: Pyrazine, 2-ethyl-3-ethylthio

Chemical compound data from PubChem database. IUPAC Name: 2-ethyl-3-ethylsulfanylpyrazine. Molecular Formula: C8H12N2S. Molecular Weight: 168.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Lack of agreement between tonometric and gastric juice partial carbon dioxide tension

Our goal was to compare measurement of tonometered saline and gastric juice partial carbon dioxide tension (PCO2). In this prospective observational study, 112 pairs of measurements were simultaneously obtained under various hemodynamic conditions, in 15 critical care patients. Linear regression analysis showed a significant correlation between the two methods of measuring PCO2 (r 2 = 0.43; P < 0.0001). However, gastric juice PCO2 was systematically higher (mean difference 51 mmHg). The 95% limits of agreement were 315 mmHg and the dispersion increased as the values of PCO2 increased. Tonometric and gastric juice PCO2 cannot be used interchangeably. Gastric juice PCO2 measurement should be interpreted with caution.
Compound 530645: p-Toluic acid, but-3-yn-2-yl ester

Chemical compound data from PubChem database. IUPAC Name: but-3-yn-2-yl 4-methylbenzoate. Molecular Formula: C12H12O2. Molecular Weight: 188.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530236: 9-(Trimethylsilyl)-2,6,8-tris[(trimethylsilyl)oxy]-9H-purine

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[9-trimethylsilyl-2,6-bis(trimethylsilyloxy)purin-8-yl]oxysilane. Molecular Formula: C17H36N4O3Si4. Molecular Weight: 456.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526600: (3,5-Diacetyloxy-4-methoxyoxan-2-yl)methyl acetate

Chemical compound data from PubChem database. IUPAC Name: (3,5-diacetyloxy-4-methoxyoxan-2-yl)methyl acetate. Molecular Formula: C13H20O8. Molecular Weight: 304.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Research Article: BMC Genetics

Background
          Blood group genotyping is increasingly utilized for prenatal diagnosis and after recent transfusions, but still lacks the specificity of serology. In whites, the presence of antigen D is predicted, if two or more properly selected RHD-specific polymorphism are detected. This prediction must fail, if an antigen D negative RHD positive allele is encountered. Excluding RHDψ and CdeS frequent only in individuals of African descent, most of these alleles are unknown and the population frequency of any such allele has not been determined.
        
        
          Methods
          We screened 8,442 antigen D negative blood donations by RHD PCR-SSP. RHD PCR positive samples were further characterized by RHD exon specific PCR-SSP or sequencing. The phenotype of the identified alleles was checked and their frequencies in Germans were determined.
        
        
          Results
          We detected 50 RHD positive samples. Fifteen samples harbored one of three new Del alleles. Thirty samples were due to 14 different D negative alleles, only 5 of which were previously known. Nine of the 14 alleles may have been generated by gene conversion in cis, for which we proposed a mechanism triggered by hairpin formation of chromosomal DNA. The cumulative population frequency of the 14 D negative alleles was 1:1,500. Five samples represented a D+/- chimera, a weak D and three partial D, which had been missed by routine serology; two recipients transfused with blood of the D+/- chimera donor became anti-D immunized.
        
        
          Conclusion
          The results of this study allowed to devise an improved RHD genotyping strategy, the false-positive rate of which was lower than 1:10,000. The number of characterized RHD positive antigen D negative and Del alleles was more than doubled and their population frequencies in Europe were defined.
Patent AT-E399864-T1: [Translated] DNA CODING FOR THE SHEEP ADENOVIRUS (OAV287) AND ITS USE AS A VIRAL VECTOR

The invention relates to an isolated DNA molecule comprising the genome of ovine adenovirus OAV287, functionally equivalent DNA molecules or portions thereof. The invention also relates to plasmids and viral vectors including the DNA molecules. The invention also relates to methods for delivering non-adenoviral DNA molecules encoding a polypeptide or polypeptides to animals and in particular to grazing animals.
Compound 525917: 17-(5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene

Chemical compound data from PubChem database. IUPAC Name: 17-(5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene. Molecular Formula: C29H46. Molecular Weight: 394.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table 1C. Arboviral diseases, St. Louis encephalitis virus disease to West Nile virus disease

NNDSS - Table 1C. Arboviral diseases, St. Louis encephalitis virus disease to West Nile virus disease - 2021. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notice: Due to data processing issues at CDC, data for the following jurisdictions may be incomplete for week 7: Alaska, Arizona, California, Connecticut, Delaware, Florida, Hawaii, Louisiana, Maryland, Michigan, Missouri, North Dakota, New Hampshire, New York City, Oregon, Pennsylvania, and Rhode Island.

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
 Max: Maximum — Maximum case count during the previous 52 weeks.
  * Case counts for reporting years 2020 and 2021 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
Compound 528095: tert-Butyl(dimethyl)silyl 3-methylbutanoate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 3-methylbutanoate. Molecular Formula: C11H24O2Si. Molecular Weight: 216.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525549: N-Benzylidene-3-chloroaniline

Chemical compound data from PubChem database. IUPAC Name: N-(3-chlorophenyl)-1-phenylmethanimine. Molecular Formula: C13H10ClN. Molecular Weight: 215.68. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401235-T1: [Translated] STORAGE DEVICE FOR TWO-WHEELERS

The parking device includes three or four holding elements (3a, 3b, 3c, 3d) for the wheel (6) of the bicycle, spread round the wheel circumference for uniform distribution of forces, One holding element (3a) is fixed, Two others (3b, 3c) are at a fixed spacing from each other and can turn about an axis (8) to adapt to the wheel size.
Compound 529057: 5,6-Dihydro-4-methyl-2,6-diisopropyl-4H-1,3,5-dithiazine

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-2,6-di(propan-2-yl)-1,3,5-dithiazinane. Molecular Formula: C10H21NS2. Molecular Weight: 219.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Capmatinib

TABRECTA (capmatinib) is an oral prescription medication from Novartis Pharmaceuticals Corporation, approved to treat adults with metastatic non-small cell lung cancer (NSCLC) that has a specific genetic mutation (MET exon 14 skipping). It comes as film-coated tablets in 150 mg and 200 mg strengths and works by inhibiting certain proteins involved in cancer cell growth. This information was generated using AI and is provided for informational and research purposes only.
Is albumin gradient or fluid to serum albumin ratio better than the pleural fluid lactate dehydroginase in the diagnostic of separation of pleural effusion?

Background
          To determine the accuracy of serum-effusion albumin gradient (SEAG) and pleural fluid to serum albumin ratio (ALBR) in the diagnostic separation of pleural effusion into transudate and exudate and to compare SEAG and ALBR with pleural fluid LDH (FLDH) the most widely used test.
        
        
          Methods
          Data collected from 200 consecutive patients with a known cause of pleural effusion in a United Kingdom district general hospital.
        
        
          Results
          The median and inter quartile ranges (IQR) for SEAG 93.5 (33.8 to 122.5) g/dl, ALBR 0.49 (0.42 to 0.62) and FLDH 98.5 IU/L(76.8 to 127.5) in transudates were significantly lower than the corresponding values for exudates 308.5 (171 to 692), 0.77 (0.63 to 0.85), 344 (216 to 695) all p < 0.0001. The Area Under the Curve (AUC) with 95% confidence intervals (Cl) for SEAG, ALBR and FLDH were 0.81 (0.75 to 0.87), 0.79 (0.72 to 0.86) and 0.9 (0.87 to 0.96) respectively. The positive likelihood ratios with 95%CI for FLDH, SEAG, and ALBR were: 7.3(3.5–17), 6.3(3–15) 6.2(3–14) respectively. There was a significant negative correlation between SEAG and ALBR (r= -0.89, p < 0.0001).
        
        
          Conclusion
          The discriminative value for SEAG and ALBR appears to be similar in the diagnostic separation of transudates and exudates. FLDH is a superior test compared to SEAG and ALBR.
Compound 528057: Bis[tert-butyl(dimethyl)silyl] 2-([tert-butyl(dimethyl)silyl]amino)pentanedioate

Chemical compound data from PubChem database. IUPAC Name: bis[tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]pentanedioate. Molecular Formula: C23H51NO4Si3. Molecular Weight: 489.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Cellular cardiomyoplasty with autologous skeletal myoblasts for ischemic heart disease and heart failure

Cell transplantation to repair or regenerate injured myocardium is a new frontier in the treatment of cardiovascular disease. Even though it is based on many years of pre-clinical studies, much remains to be understood about this methodology, even as it progresses to the clinic. For example, controversies exist over the specific cells to be used, the dosages needed for tissue repair, how cells will affect the electrical activity of the myocardium, and even whether the cells can improve myocardial function after transplantation — all of which are briefly reviewed here. Autologous skeletal myoblasts appear to be the most well studied and best first generation cells for cardiac repair. Yet cardiocytes and, more recently, stem cells have been proposed as cell sources for this technology. Their advantages and limitations are also discussed. Although cellular cardiomyoplasty (cell transplantation for cardiac repair) shows great pre-clinical promise, its future will heavily depend on conducting carefully controlled, randomized clinical trials with appropriate endpoints. Utilizing biologically active cells provides both an opportunity for tissue repair and the potential for not yet understood outcomes. As with any frontier, many pioneers will attempt to conquer it. But also as with any frontier, there are pitfalls and consequences to be considered that may surpass those of previous endeavors. The future thus requires careful consideration and well-designed trials rather than haste. The promise for cell transplantation is too great to be spoiled by ill-designed attempts that forget to account for the biology of both the cells and the myocardium.