AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 527315: Methyl 2-[3-fluoro-4-(4-methoxyphenyl)phenyl]propanoate

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[3-fluoro-4-(4-methoxyphenyl)phenyl]propanoate. Molecular Formula: C17H17FO3. Molecular Weight: 288.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400623-T1: [Translated] SURFACE MATERIAL

An overlay for sports equipment such as skis, sticks or rackets or for housings for domestic or electrical equipment, furniture or machines includes a single-layer film based on copolyamide PA 6/12 or a multi-layer film containing PA 6/12 and is such that the PA 6/12 layer also contains a polyamide homopolymer comprising PA 6, PA 12, PA 610 and/or PA 612. An independent claim is also included for production of the overlay involving (co)extrusion at above 200[deg]C of a mixture of PA 6/12 with one or more of the specified homopolymers, followed by calendering of the film obtained.
Role of CD28/B7 costimulation and IL-12/IL-10 interaction in the radiation-induced immune changes

Background
          The present paper aims at studying the role of B7/CD28 interaction and related cytokine production in the immunological changes after exposure to different doses of ionizing radiation.
        
        
          Results
          The stimulatory effect of low dose radiation (LDR) on the proliferative response of lymphocytes to Con A was found to require the presence of APCs. The addition of APCs obtained from both low- and high-dose-irradiated mice to splenic lymphocytes separated from low-dose-irradiated mice caused stimulation of lymphocyte proliferation. B7-1/2 expression on APCs was up-regulated after both low and high doses of radiation. There was up-regulation of CD28 expression on splenic and thymic lymphocytes after LDR and its suppression after high dose radiation (HDR), and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expression showed changes in the opposite direction. IL-12 secretion by macrophages was stimulated after both low and high doses of radiation, but IL-10 synthesis by splenocytes was suppressed by low dose radiation and up-regulated by high dose radiation.
        
        
          Conclusion
          The status of CD28/CTLA-4 expression on T lymphocytes in the presence of up-regulated B7 expression on APCs determined the outcome of the immune changes in response to radiation, i.e., up-regulation of CD28 after LDR resulted in immunoenhancement, and up-regulation of CTLA-4 associated with down-regulation of CD28 after HDR led to immunosuppression. Both low and high doses of radiation up-regulated B7-1/2 expression on APCs. After LDR, the stimulated proliferative effect of increased IL-12 secretion by APCs, reinforced by the suppressed secretion of IL-10, further strengthened the intracellular signaling induced by B7-CD28 interaction.
Prevention Agenda 2019-2024 Tracking Indicators: County Most Recent Data

There are two datasets related to the County Level Prevention Agenda Tracking Indicators posted on this site. Each dataset consists of county level data for 70 health tracking indicators and sub-indicators for the Prevention Agenda 2019-2024: New York State’s Health Improvement Plan.  A health tracking indicator is a metric through which progress on a certain area of health improvement can be assessed.  The indicators are organized by the Priority Area of the Prevention Agenda as well as the Focus Area under each Priority Area. The data sets also include indicators about major cross-cutting health outcomes and about health disparities. Each dataset includes tracking indicators for the five Priority Areas of the Prevention Agenda 2019-2024.  The most recent year dataset includes the most recent county level data for all indicators. The trend dataset includes the most recent county level data and historical data, where available. Each dataset also includes the Prevention Agenda 2024 state objectives for the indicators. Sub-indicators are included in these datasets to measure health disparities among socioeconomic groups.
Medicare Monthly Enrollment

The Medicare Monthly Enrollment data provides current monthly information on the number of Medicare beneficiaries with hospital/medical coverage and prescription drug coverage, available for several geographic areas including national, state/territory, and county. The hospital/medical coverage data can be broken down further by health care delivery (Original Medicare versus Medicare Advantage and Other Health Plans) and the prescription drug coverage data can be examined by those enrolled in stand-alone Prescription Drug Plans and those enrolled in Medicare Advantage Prescription Drug plans. The dataset provides monthly and yearly enrollee trends.
Compound 530550: 4-Ethylbenzoic acid, heptyl ester

Chemical compound data from PubChem database. IUPAC Name: heptyl 4-ethylbenzoate. Molecular Formula: C16H24O2. Molecular Weight: 248.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526910: 2-Isopentoxyethyl TMS ether

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-(3-methylbutoxy)ethoxy]silane. Molecular Formula: C10H24O2Si. Molecular Weight: 204.38. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529994: Undecanoic acid, 2-chloro, methyl ester

Chemical compound data from PubChem database. IUPAC Name: ethyl 2-chloroundecanoate. Molecular Formula: C13H25ClO2. Molecular Weight: 248.79. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Complex splicing pattern generates great diversity in human

Background
          Mutation analysis of the neurofibromatosis type 1 (NF1) gene has shown that about 30% of NF1 patients carry a splice mutation resulting in the production of one or several shortened transcripts. Some of these transcripts were also found in fresh lymphocytes of healthy individuals, albeit typically at a very low level. Starting from this initial observation, we were interested to gain further insight into the complex nature of NF1 mRNA processing.
        
        
          Results
          We have used a RT-PCR plasmid library based method to identify novel NF1 splice variants. Several transcripts were observed with specific insertions/deletions and a survey was made. This large group of variants detected in one single gene allows to perform a comparative analysis of the factors involved in splice regulation. Exons that are prone to skipping were systematically analysed for 5' and 3' splice site strength, branch point strength and secondary structure.
        
        
          Conclusion
          Our study revealed a complex splicing pattern, generating a great diversity in NF1 transcripts. We found that, on average, exons that are spliced out in part of the mRNA have significantly weaker acceptor sites. Some variants identified in this study could have distinct roles and might expand our knowledge of neurofibromin.
2014 CMHS Uniform Reporting System (URS) Table for Vermont

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Vermont. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an intensive worldwide search and the introduction of selective COX-2 inhibitors. In this review, recent advances in understanding the mechanism of action of NSAIDs and, in this context, clinical findings on NSAID-induced gastrointestinal side effects are summarized. This knowledge is important for the effective treatment of pain and inflammation, as well as for preventing serious and sometimes lethal gastrointestinal side effects.
Preneoplastic lesions of the lung

Lung cancer is the leading cause of cancer deaths worldwide. If we can define and detect preneoplastic lesions, we might have a chance of improving survival. The World Health Organization has defined three preneoplastic lesions of the bronchial epithelium: squamous dysplasia/carcinoma in situ; atypical adenomatous hyperplasia; and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. These lesions are believed to progress to squamous cell carcinoma, adenocarcinoma and carcinoid tumors, respectively. In this review we summarize the data supporting the preneoplastic nature of these lesions, and delve into some of the genetic changes found in atypical adenomatous hyperplasia and squamous dysplasia/carcinoma in situ.
Compound 530607: p-Anisic acid, heptadecyl ester

Chemical compound data from PubChem database. IUPAC Name: heptadecyl 4-methoxybenzoate. Molecular Formula: C25H42O3. Molecular Weight: 390.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527539: Perfluoroundecane

Chemical compound data from PubChem database. IUPAC Name: 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-tetracosafluoroundecane. Molecular Formula: C11F24. Molecular Weight: 588.08. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Elk Creek Seismic Waveforms 2011 (Part 7 of 19)

Coal bursts (damaging seismic events in underground coal mines) pose a substantial threat to operations and mine workers. The underground coal mines in Colorado’s North Fork Valley (NFV) have experienced many coal bursts, often with distinct characteristics from those of other US coal mining regions. To better understand these events and manage their associated risks, the National Institute for Occupational Safety and Health undertook a long-term monitoring campaign at the Elk Creek Mine in the NFV. The monitoring efforts included a seismic network composed of both surface and underground sensors, borehole pressure cells (BPCs), instrumented support Cans, convergence monitors, ground condition surveys, and several other data sources. This dataset consists of the event waveform files from the seismic network for the 983,379 events that were detected during the monitoring campaign. The waveforms are stored in HDF5 files that are broken up by week. Within the HDF5 files, the data are organized by station id, event time, and channel. The amplitudes are velocity in meters/second.
 
This is download 15 of 48 and corresponds to the time range between February 14, 2011, and March 7, 2011.
Compound 525664: p-Bromobenzylidene-(4-nitrophenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-(4-nitrophenyl)methanimine. Molecular Formula: C13H9BrN2O2. Molecular Weight: 305.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528911: Mandelic acid, 3-hydroxy, DCTFA-acetate

Chemical compound data from PubChem database. IUPAC Name: [3-[2,2-bis[chloro(difluoro)methyl]-5-oxo-1,3-dioxolan-4-yl]phenyl] acetate. Molecular Formula: C13H8Cl2F4O5. Molecular Weight: 391.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
All Payer Opioid-Related Facility Visits in New York State: Beginning 2010 (SPARCS)

<b>Note: This dataset is no longer being updated. For continued updates related to this information, please visit: https://www.health.ny.gov/statistics/opioid/#i_one.</b> This dataset is a summary of inpatient discharges and outpatient visit data for opioid-related diagnosis. The data reflects selected diagnosis codes that include a range of poisonings by opiates, opium, heroin, methadone, and other related narcotics. Please refer to the data dictionary in the “About” section for information on the current data available.
Program Instruction (PI-16-04)

This Program Instruction (PI) provides guidance to Indian tribes, tribal organizations, and tribal consortia (tribes) on actions they are required to take in order to receive their allotments for Fiscal Year (FY) 2017 (subject to the availability of appropriations) authorized under title IV-B, subparts 1 and/or 2, the CFCIP, and the ETV program. Please note that tribes with either an approved title IV-E plan or a title IV-E tribal/state cooperative agreement or contract have the option to apply to receive FY 2017 CFCIP and/or ETV funds directly from the Secretary. (See Section D of this PI.)

PI-16-04 (PDF)

Fiscal Year 2016 Allotment Title IV-B, Subpart 1 - Stephanie Tubbs Jones Child Welfare
Services
Fiscal Year 2016 Allotment Title IV-B, Subpart 2 - Promoting Safe and Stable Families
Fiscal Year 2016 Chafee Foster Care Independence Program and Education and Training Voucher Program

CFS-101 Part I:  Annual Budget Request for Title IV-B, Subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Program Instructions
CFS-101 Part I:  Annual Budget Request for Title IV-B, Subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Program Form (Excel (XLSX) - 13 KB)
CFS-101, Part II: Annual Summary of Child and Family Services Instructions
CFS-101, Part II: Annual Summary of Child and Family Services Form (Excel (XLSX) - 13 KB)
CFS-101, Part III: Annual Expenditures for Title IV-B, Subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Instructions
CFS-101, Part III: Annual Expenditures for Title IV-B, Subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Form (Excel (XLSX) - 12 KB)

Certification of Tribal Population Under Age 21 (Word (DOCX) - 33 KB)

Children’s Bureau Regional Program Managers

Metadata-only record linking to the original dataset. Open original dataset below.
Patent AT-E400590-T1: [Translated] POLYMERIZATION PROCESS FOR PRODUCING POROUS PROPYLENE POLYMERS AND THE POLYMERS SO PRODUCED

Described is a process for the polymerization of olefins carried out in the presence of a catalyst comprising the product of the reaction of an Al-trialkyl compound and a catalyst component comprising a titanium compound containing at least one Ti-halogen link supported on anhydrous magnesium chloride, said component being in the form of spherical particles with an average diameter between 10 and 350  mu m, surface area between 20 and 250 m<2>/g, porosity greater than 0.2 cc/g, having an X-ray spectrum where a) reflections at angle 2 theta of 35 DEG  and 2 theta  of 14.95 DEG  are present, or b) where the reflection at 2 theta  angle of 35 DEG  is no longer present but is substituted by a halo with a maximum intensity between angles 2  theta  of 33.5 DEG  and 35 DEG , and the reflection at angle 2 theta  of 14.95 DEG  is not present.
Compound 526880: 2-[2-(2-Isopentoxyethoxy)ethoxy]ethyl acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-(3-methylbutoxy)ethoxy]ethoxy]ethyl acetate. Molecular Formula: C13H26O5. Molecular Weight: 262.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Sequence permutations in the molecular evolution of DNA methyltransferases

Background
          DNA methyltransferases (MTases), unlike MTases acting on other substrates, exhibit sequence permutation. Based on the sequential order of the cofactor-binding subdomain, the catalytic subdomain, and the target recognition domain (TRD), several classes of permutants have been proposed. The majority of known DNA MTases fall into the α, β, and γ classes. There is only one member of the ζ class known and no members of the δ and ε classes have been identified to date. Two mechanisms of permutation have been proposed: one involving gene duplication and in-frame fusion, and the other involving inter- and intragenic shuffling of gene segments.
        
        
          Results
          Two novel cases of sequence permutation in DNA MTases implicated in restriction-modification systems have been identified, which suggest that members of the δ and ζ classes (M.MwoI and M.TvoORF1413P, respectively) evolved from β-class MTases. This is the first identification of the δ-class MTase and the second known ζ-class MTase (the first ζ-class member among DNA:m4C and m6A-MTases).
        
        
          Conclusions
          Fragmentation of a DNA MTase gene may result from attack of nucleases, for instance when the RM system invades a new cell. Its reassembly into a functional form, the order of motifs notwithstanding, may be strongly selected for, if the cognate ENase gene remains active and poses a threat to the host's chromosome. The "cut-and-paste" mechanism is proposed for β-δ permutation, which is non-circular and involves relocation of one segment of a gene. The circular β-ζ permutation may be explained both by gene duplication or shuffling of gene fragments. These two mechanisms are not mutually exclusive and probably both played a role in the evolution of permuted DNA MTases.
Patent AT-E40018-T1: [Translated] COMPRESSED GAS SWITCH CAN BE MOUNTED AND REMOVED WITHOUT SIGNIFICANT GAS LOSS.

The circuit breaker comprises first (2A) and second (2B) compressed-gas-filled enclosures, said first enclosure containing fixed contacts and a moving assembly comprising contacts cooperating with said fixed contacts, which moving assembly is movable by means of a control rod (12), said second enclosure containing a connecting rod (30) articulated on a crank (40) swivelling about a shaft (41) going through the housing of the control mechanism and connected on the outside of said housing with rotational driving means, said first and second enclosures (2A, 2B) being coaxially superposed and attached together when the circuit breaker is assembled, rods (12) and (30) being fast end to end, the moving assembly then having an operating stroke going from a first position where the breaker is open to a second position where the breaker is closed. The moving assembly can be moved beyond said second, closed breaker position by an overstroke obtained by an increased rotation of said shaft (41), the latter having means for locking it in overstroke position, said first enclosure comprising a sliding, tubular air lock ( 50) able, when the moving assembly is in overstroke position, to assume a position sealingly closing off said first enclosure.
Calcitriol

Calcitriol is a prescription medication that acts as a vitamin D analog to help regulate calcium and phosphorus levels in the body. It's used to treat conditions like hypocalcemia (low blood calcium) in patients with kidney disease or certain metabolic disorders. Available as oral capsules in strengths of 0.25 mcg and 0.5 mcg, it's manufactured by Bionpharma Inc. and marketed under the brand name Calcitriol. This information was generated using AI and is provided for informational and research purposes only.
Patent AT-E399800-T1: [Translated] NITROGEN SUBSTITUTED PHOSPHINIMIN LIGAND

An organometallic complex of a group 4 metal having a cyclopentadienyl ligand and a heterosubstituted phosphinimine ligand is a catalyst component for olefin polymerization. The heterosubstituted phosphinimine ligand may be conveniently and inexpensively synthesized using readily available precursors which are comparatively non-pyrophoric. The resulting catalysts are highly active for ethylene copolymerization, particularly when activated with an alumoxane or ionic activator.
Compound 528066: tert-Butyl(dimethyl)silyl 2-([tert-butyl(dimethyl)silyl]amino)-3-([tert-butyl(dimethyl)silyl]oxy)butanoate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]-3-[tert-butyl(dimethyl)silyl]oxybutanoate. Molecular Formula: C22H51NO3Si3. Molecular Weight: 461.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401655-T1: [Translated] RESIDUAL CURRENT SWITCH AND MAGNETIC CORE FOR A RESIDUAL CURRENT SWITCH

The breaker has a summation current transformer with a soft magnetic core (2) made of nano-crystalline iron base alloy and with differential windings (4, 5) attached on the core. A relay (3) is connected with a measuring coil (7) of the transformer. The magnetic core exhibits a maximum permeability of more than 350 and a remanence ratio of more than 0.7, where the alloy has a structure, which consists of fine crystalline grains.
Immunodepression in the surgical patient and increased susceptibility to infection

Multiple organ failure is the major problem in intensive care patients. The failure of the organ 'immune system' is frequently overlooked, however. In this issue the article by Angele and Faist provides an excellent review of the topic. Deactivation of monocyte and lymphocyte functions seems to play a key role in post-traumatic immunodepression. To accompany that review we summarize our knowledge of the mechanisms of deactivation. Stress response, lipopolysaccharide translocalization and tissue injury contribute to 'immunoparalysis'. Recently developed, well standardized assays now allow us to monitor the immune system like other organ functions and opens new approaches for therapeutic interventions.
Behavioral Health Barometer: Wisconsin, 2014

This is a behavioral health report for the state of Wisconsin. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment, and medicare enrollees for the years 2009 to 2013.
Dextrose and potassium chloride

Potassium Chloride in Dextrose is an intravenous solution that provides essential fluids, electrolytes (like potassium), and calories to the body. It's used to treat or prevent dehydration and electrolyte imbalances, often in medical settings. Available in various strengths, it's administered by injection under prescription. This information was generated using AI and is provided for informational and research purposes only.