AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 529872: 2-(2-Furfuryl)-6-methylpyrazine

Chemical compound data from PubChem database. IUPAC Name: 2-(furan-2-ylmethyl)-6-methylpyrazine. Molecular Formula: C10H10N2O. Molecular Weight: 174.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400636-T1: [Translated] MACHINE DISHWASHING DETERGENT WITH SPECIAL POLYMER BLEND

The present invention relates to detergents and rinse agents for machine dishwashing and to supply forms which combine detergent and rinse agent containing certain polymers in a single product comprising at least one polymer with cationic monomer units and at least one anionic polymer modified with phosphorus- and/or sulfur-containing groups, characterized in that the pH value of a 1% by weight solution of the anionic polymer in distilled water at 20° C. is less than pH 6.
Compound 527134: 3,6-Dichloro-dibenzothiophene

Chemical compound data from PubChem database. IUPAC Name: 3,6-dichlorodibenzothiophene. Molecular Formula: C12H6Cl2S. Molecular Weight: 253.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Development of porcine embryos reconstituted with somatic cells and enucleated metaphase I and II oocytes matured in a protein-free medium

Background
          Many cloned animals have been created by transfer of differentiated cells at G0/G1 or M phase of the cell cycle into enucleated M II oocytes having high maturation/meiosis/mitosis-promoting factor activity. Because maturation/meiosis/mitosis-promoting factor activity during oocyte maturation is maximal at both M I and M II, M I oocytes may reprogram differentiated cell nuclei as well. The present study was conducted to examine the developmental ability in vitro of porcine embryos reconstructed by transferring somatic cells (ear fibroblasts) into enucleated M I or M II oocytes.
        
        
          Results
          Analysis of the cell cycle stages revealed that 91.2 ± 0.2% of confluent cells were at the G0/G1 phase and 54.1 ± 4.4% of nocodazole-treated cells were at the G2/M phase, respectively. At 6 h after activation, nuclear swelling was observed in 50.0-88.9% and 34.4-39.5% of embryos reconstituted with confluent cells and nocodazole-treated cells regardless of the recipient oocytes, respectively. The incidence of both a swollen nucleus and polar body was low (6.3-10.5%) for all nocodazole-treated donor cell regardless of the recipient oocyte. When embryos reconstituted with confluent cells and M I oocytes were cultured, 2 (1.5%) blastocysts were obtained and this was significantly (P < 0.05) lower than that (7.6%) of embryos produced by transferring confluent cells into M II oocytes. No reconstructed embryos developed to the blastocyst stage when nocodazole-treated cells were used as donors.
        
        
          Conclusions
          Porcine M I oocytes have a potential to develop into blastocysts after nuclear transfer of somatic cells.
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Metadata-only record linking to the original dataset. Open original dataset below.
2010 State Profile — Rhode Island

This state profile includes data from facilities in Rhode Island that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Rhode Island. In Rhode Island, 53 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 7,362 clients in substance abuse treatment on March 31, 2010. The survey response rate in Rhode Island was 87.1%.
NNDSS - Table II. West Nile virus disease

NNDSS - Table II. West Nile virus disease - 2016.  In this Table, provisional* cases of selected† notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed.  The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories.
Note:
These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. 

Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. 

Footnotes:
C.N.M.I.: Commonwealth of Northern Mariana Islands. 
U: Unavailable.    -: No reported cases.    N: Not reportable.    NN: Not Nationally Notifiable.   NP:  Nationally notifiable but not published.    Cum: Cumulative year-to-date counts.    Med: Median.    Max: Maximum. 

* Case counts for reporting year 2016 are provisional and subject to change.   For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for TB are displayed in Table IV, which appears quarterly. 
† Three low incidence conditions, rubella, rubella congenital, and tetanus, have been moved to Table II to facilitate case count verification with reporting jurisdictions. 
§ Updated weekly from the Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases (ArboNET Surveillance).  Data for Jamestown Canyon virus, La Crosse virus, Chikungunya virus, Eastern equine encephalitis virus, Powassan virus, St. Louis virus, and Western equine encephalitis virus diseases are available in Table I. 
¶ Not reportable in all states. Reporting exceptions are available at http://wwwn.cdc.gov/nndss/downloads.html.
Compound 526571: 2,10,16-Trimethyldotriacontane

Chemical compound data from PubChem database. IUPAC Name: 2,10,16-trimethyldotriacontane. Molecular Formula: C35H72. Molecular Weight: 492.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2012 Uniform Reporting System (URS) Tables for Missouri

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Patent AT-E401221-T1: [Translated] PEDESTRIAN PROTECTION DEVICE AND METHOD FOR ADJUSTING LOAD CHARACTERISTICS OF THE DEVICE

In a pedestrian protection apparatus installed in a lower part of a front of a vehicle, a plate extends in a longitudinal direction of the vehicle, and includes a front section (26) having at least a portion protruding from the front of the vehicle, a rear section (28) fixed to the vehicle, and a center section provided between the front and rear sections. The front section (30) is more rigid than the rear section, and the center section is less rigid than the front section and more rigid than the rear section.
Compound 527423: Carvacrol isobutyrate

Chemical compound data from PubChem database. IUPAC Name: (2-methyl-5-propan-2-ylphenyl) 2-methylpropanoate. Molecular Formula: C14H20O2. Molecular Weight: 220.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529819: Methanal, 2,4,6-trichlorophenyl hydrazone

Chemical compound data from PubChem database. IUPAC Name: 2,4,6-trichloro-N-(methylideneamino)aniline. Molecular Formula: C7H5Cl3N2. Molecular Weight: 223.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400663-T1: [Translated] RECOMBINASE-POLYMERASE AMPLIFICATION

This disclosure describes three related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of the bacterial RecA and related proteins, to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The disclosed method has the advantage of not requiring thermocycling or thermophilic enzymes. Further, the improved processivity of the disclosed methods allow amplification of DNA up to hundreds of megabases in length.
Allopurinol sodium

Allopurinol Sodium is a prescription injectable medication, available as a lyophilized powder for intravenous solution. Each vial contains 500 mg of allopurinol sodium, equivalent to 500 mg base. It's a xanthine oxidase inhibitor used to manage conditions like gout. Manufactured by Hikma Pharmaceuticals USA Inc. under ANDA 076870. This information was generated using AI and is provided for informational and research purposes only.
Compound 528773: Dihydrosarsasapogenin 26-tosylate

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36,38,38,40,40,42,42,44,44,46,46,48,48,50,50,52,52,54,54,56,56,58,58,60,60,62,62,64,64-tetrahexacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59,61,63-dotriacontaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64-dotriacontasilacyclotetrahexacontane. Molecular Formula: C64H192O32Si32. Molecular Weight: 2372.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Sub-County Data for Selected Health Outcomes in New York State, 2008-2012

This dataset includes average annual crude and age-adjusted rates for asthma, chronic obstructive pulmonary disease (COPD) and myocardial infarction (MI) in New York State at sub-county resolution for the time period 2008-2012. Emergency Department (ED) visit and hospitalization data for these health outcomes in NYS were generated from the Statewide Planning and Research Cooperative System (SPARCS) database which collects information on discharges from hospitals in NYS.
</br>
The data reflect people who have a health condition that is serious enough to require a hospital admission or ED visit and do not include conditions managed through visit to a primary care physician. Data show the number of hospitalizations or ED visits rather than the number of patients who were admitted or seen for each illness.
</br>
For more information, visit https://health.ny.gov/environmental/public_health_tracking/.
Compound 529346: 2-Ethyl-4-prop-1-en-2-ylpyridine

Chemical compound data from PubChem database. IUPAC Name: 2-ethyl-4-prop-1-en-2-ylpyridine. Molecular Formula: C10H13N. Molecular Weight: 147.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Induction of apoptosis in rat peripheral blood lymphocytes by the
anticancer drug CI-994 (acetyldinaline)

Abstract
          CI-994 (acetyldinaline) is an investigational anticancer drug currently in clinical trials. In preclinical safety studies in rats and dogs, CI-994 resulted in significant toxicity to bone marrow and lymphoid tissue. To determine if apoptosis was involved in CI-994 toxicity, peripheral blood lymphocytes were
isolated from untreated male Wistar rats and exposed to CI-994 (1, 3, 10, or 30 μM) in vitro for up to 24 hours. Morphological and biochemical features of apoptosis were evaluated using several techniques, and lactate dehydrogenase (LDH) release was measured as an indicator of cell necrosis. No evidence of apoptosis or necrosis was detected in lymphocytes exposed to CI-994 for 4 hours. After 24 hours, concentration-dependent increases in apoptosis characterized by DNA condensation, DNA fragmentation, and/or externalization of phosphatidyl serine were seen at CI-994 concentrations as low as 1 μM and were statistically significant beginning at 10 μM. Ultrastructural analysis confirmed the presence of DNA condensation, DNA fragmentation, cell shrinkage, and membrane blebbing in cells exposed to 30 μM CI-994. After 24 hours, the percent of maximum LDH release from lymphocytes treated with 10 and 30 μM CI-994 was 7% and 15%, respectively, compared with 0% in the controls. In comparison, morphological changes of apoptosis detected by fluorescent microscopy were observed in 79% of the lymphocytes at these two concentrations. Additionally, apoptosis was seen in more than 24% of lymphocytes exposed to 1 and 3 μM CI-994, whereas maximum LDH release was less than or equal to 1% at these concentrations. These results show that apoptosis is the primary mode of cell death in rat lymphocytes exposed to CI-994 in vitro.
National Child Abuse and Neglect Data System (NCANDS) Child File: Findings from the National Child Abuse and Neglect Data System (NCANDS) - Data tables (from Child Maltreatment 2018)

<p>The National Child Abuse and Neglect Data System (NCANDS) Child File data set consists of child-specific data of all reports of maltreatment to State child protective service agencies that received an investigation or assessment response. NCANDS is a Federally-sponsored national data collection effort created for the purpose of tracking the volume and nature of child maltreatment reporting each year within the United States. The Child File is the case-level component of the NCANDS. Child File data are collected annually through the voluntary participation of States. Participating States submit their data after going through a process in which the State's administrative system is mapped to the NCANDS data structure.  Data elements include the demographics of children and their perpetrators, types of maltreatment, investigation or assessment dispositions, risk factors, and services provided as a result of the investigation or assessment.</p>
Compound 525700: N-(4-Methoxybenzylidene)-P-phenetidine

Chemical compound data from PubChem database. IUPAC Name: N-(4-ethoxyphenyl)-1-(4-methoxyphenyl)methanimine. Molecular Formula: C16H17NO2. Molecular Weight: 255.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Locations of several novel 2'-

Background
          Ribose 2'-O-methylation, the most common nucleotide modification in mammalian rRNA, is directed by the C/D box small nucleolar RNAs (snoRNAs). Thus far, more than fifty putative human rRNA methylation guide snoRNAs have been identified. For nine of these snoRNAs, the respective ribose methylations in human 28S rRNA have been only presumptive.
        
        
          Results
          In this study, the methylation state of human 28S rRNA in the positions predicted by the snoRNAs U21, U26, U31, U48, U50, U73, U74, U80 and U81 was assessed using reverse transcription-based methods and several novel 2'-O-methylations were localized.
        
        
          Conclusions
          Seven novel ribose 2'-O-methylated residues (Am389, Am391, Gm1604, Gm1739, Gm2853, Cm3810, Gm4156, predicted by snoRNAs U26, U81, U80, U73, U50, U74 and U31, respectively) have been localized in human 28S rRNA. The total number of 2'-O-methylations in human rRNA is not yet known.
Compound 530374: 1,3-Benzenediol, 4-chloro, bis-TMS

Chemical compound data from PubChem database. IUPAC Name: (2-chloro-5-trimethylsilyloxyphenoxy)-trimethylsilane. Molecular Formula: C12H21ClO2Si2. Molecular Weight: 288.91. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Receptorphin: A conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells

Background
          In addition to endogenous opioids, a number of peptide sequences, derived from endogenous (hemorphins, alphaS1-casomorphin), and exogenous proteins (casomorphins, exorphins) have been reported, possessing opioid activity. In the present work, we report the identification of a new peptide, receptorphin (Tyr-Ile-Phe-Asn-Leu), derived from the sequence of the second transmembrane loop of the opioid receptor. This sequence is unique for the opioid receptor, and conserved in all species and receptor-types.
        
        
          Results and Discussion
          Receptorphin competes for opioid binding, presenting a kappa-receptor interaction, while it binds equally to delta- and mu- opioid and somatostatin-binding sites, and inhibits the cell proliferation of a number of human cancer cell lines, in a dose-dependent and reversible manner, at the picomolar or the nanomolar range. Receptorphin shows a preferential action on prostate cancer cells.
        
        
          Conclusion
          Our work identifies, for the first time a peptide, in a receptor sequence, possessing ligand-agonistic activities. A hypothesis, based on receptorphin liberation after cell death, is presented, which could tentatively explain the time-lag observed during opioid antiproliferative action.
The role of the Zn(II) binding domain in the mechanism of

Background
          Escherichia coli DNA topoisomerase I binds three Zn(II) with three tetracysteine motifs which, together with the 14 kDa C-terminal region, form a 30 kDa DNA binding domain (ZD domain). The 67 kDa N-terminal domain (Top67) has the active site tyrosine for DNA cleavage but cannot relax negatively supercoiled DNA. We analyzed the role of the ZD domain in the enzyme mechanism.
        
        
          Results
          Addition of purified ZD domain to Top67 partially restored the relaxation activity, demonstrating that covalent linkage between the two domains is not necessary for removal of negative supercoils from DNA. The two domains had similar affinities to ssDNA. However, only Top67 could bind dsDNA with high affinity. DNA cleavage assays showed that the Top67 had the same sequence and structure selectivity for DNA cleavage as the intact enzyme. DNA rejoining also did not require the presence of the ZD domain.
        
        
          Conclusions
          We propose that during relaxation of negatively supercoiled DNA, Top67 by itself can position the active site tyrosine near the junction of double-stranded and single-stranded DNA for cleavage. However, the interaction of the ZD domain with the passing single-strand of DNA, coupled with enzyme conformational change, is needed for removal of negative supercoils.
Compound 525379: 2,5,5-Trimethyl-4-thiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-(2-methylpropylsulfanyl)butane. Molecular Formula: C9H20S. Molecular Weight: 160.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
COVID-19 State Profile Report - Utah

<b>After over two years of public reporting, the State Profile Report will no longer be produced and distributed after February 2023. The final release was on February 23, 2023. We want to thank everyone who contributed to the design, production, and review of this report and we hope that it provided insight into the data trends throughout the COVID-19 pandemic.
Data about COVID-19 will continue to be updated at <a href='https://covid.cdc.gov/covid-data-tracker/#datatracker-home' >CDC’s COVID Data Tracker</a>.
 </b>

<p>
The State Profile Report (SPR) is generated by the Data Strategy and Execution Workgroup in the Joint Coordination Cell, in collaboration with the White House. It is managed by an interagency team with representatives from multiple agencies and offices (including the United States Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention, the HHS Assistant Secretary for Preparedness and Response, and the Indian Health Service). The SPR provides easily interpretable information on key indicators for each state, down to the county level.
 </p>

It is a weekly snapshot in time that:
<ul>
<li>Focuses on recent outcomes in the last seven days and changes relative to the month prior</li>
<li>Provides additional contextual information at the county level for each state, and includes national level information</li>
<li>Supports rapid visual interpretation of results with color thresholds</li>
</ul>
Compound 525514: Methyl 2-methylbenzyl sulfide

Chemical compound data from PubChem database. IUPAC Name: 1-methyl-2-(methylsulfanylmethyl)benzene. Molecular Formula: C9H12S. Molecular Weight: 152.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
State Estimates of Substance Use and Mental Disorders from the 2009-2010 National Surveys on Drug Use and Health

This report presents State estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Rate PUF - PY2015

The Rate PUF (Rate-PUF) is one of the seven files that make up the Marketplace PUF. The Rate-PUF contains plan-level data on individual rates based on an eligible subscriber’s age, tobacco use, and geographic location. These data either originate from the Rate Table template (i.e., template field), an Excel based form used by issuers to describe their plans in the QHP/SADP application process, or were generated by CCIIO for use in data processing (i.e., system-generated).