AndreaBozzo/ceres-open-data-index huggingface dataset:
Saline lavage with substitution of bovine surfactant in term neonates
		  with meconium aspiration syndrome (MAS) transferred for extracorporeal membrane
		  oxygenation (ECMO): a pilot study

Background:
          Meconium aspiration syndrome (MAS) is still a condition associated
				with a high mortality, and many patients require extracorporeal membrane
				oxygenation (ECMO) as rescue therapy. Beneficial effects of surfactant and
				perflubron lavage have been reported. However, pure surfactant supplementation
				has not been proven to be beneficial in the most severe forms of MAS. This
				study was performed to demonstrate an improvement in oxygenation in neonates
				transferred for ECMO and fulfilling ECMO criteria with a saline lavage and
				surfactant resupplementation.
        
        
          Methods:
          Twelve newborns with MAS [gestational age 36–40 weeks, mean birth
				weight 3200 g, age 4–16 h, oxygenation index (OI) > 40] transferred for ECMO
				therapy were treated with saline lavage (5–10 cm3/kg body weight, as
				long as green colored retrieval was observed) and resupplementation with bovine
				surfactant (Alveofact, Boehringer, Ingelheim, Germany). The OI at admission and
				3 h after this procedure was compared using the t-test for paired
				samples. ECMO was available as rescue therapy at all times.
        
        
          Results:
          The OI decreased from 49.4 (SD ± 13.3) to 27.4 (SD ± 7.3),
				P < 0.01. The decrease was sustained in nine patients, three
				patients required ECMO and all patients survived.
        
        
          Conclusions:
          As MAS is a condition with parenchymal damage, pulmonary
				hypertension and obstructive airway disease, no simple causative therapy is
				possible. Surfactant application after removal of meconium by extensive lavage
				is feasible as long as 16 h after birth even in infants considered for ECMO
				therapy; it might reduce the necessity of ECMO.
Compound 529047: Ethanediol, pentylboronate

Chemical compound data from PubChem database. IUPAC Name: 2-pentyl-1,3,2-dithiaborolane. Molecular Formula: C7H15BS2. Molecular Weight: 174.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401396-T1: [Translated] METHOD FOR FUSING DENDRITIC CELLS WITH TUMOR CELLS AND MEDIA FOR SUCH METHOD

Fusing dendritic cells (DC) and tumor cells (TC) in which the two cell types are mixed; optionally washed; centrifuged, then the pellet taken up in electrofusion medium (EFM) and subjected to electrofusion. EFM contains, in pyrogen-free, sterile, distilled water 20-150 mM sugar (I), 0.05-1 mM magnesium salt (II) and 0.01-1 mM calcium salt (III). Independent claims are also included for the following: (1) an Electrofusion Medium (EFM); and (2) a washing medium (WM) containing 270-310 mM (I), 0.05-1 mM (II) and 0.01-1 mM (III).
Genomic structure of the gene for mouse germ cell nuclear factor (GCNF)

Background:
          The germ cell nuclear factor (GCNF, also known as retinoid acid receptor-related testis-associated receptor, neuronal cell nuclear receptor or NR6A1) is an orphan receptor in the nuclear receptor superfamily found in mammals, amphibians and fish. The mouse Gcnf gene is expressed in the placenta and the developing nervous system and germ cells, and responds to retinoic acid.
        
        
          Results:
          We have defined the intron-exon structure of the mouse Gcnf gene and found that it contains 11 exons. Exons 1-4 encode the 75 amino acid amino-terminal domain and exon 4 also encodes the core DNA-binding domain. The carboxy-terminal extension is encoded by exon 5, exons 6 and 7 encode the hinge region, and exons 7-11 encode the putative ligand-binding domain. Unusually, the two zinc-finger motifs in the DNA-binding domain are encoded by separate exons.
        
        
          Conclusions:
          The protein-coding region of GCNF is contained in 11 exons. The genomic structure of this nuclear receptor gene will be useful for further studies.
Texas (TX)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Texas overall and for substate regions within Texas. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
2014 CMHS Uniform Reporting System (URS) Table for Arizona

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Arizona. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
MDCOVID-19 Total Currently Hospitalized Adult and Pediatric Acute and ICU

<b>Summary</b>
The daily occupancy number of COVID-19 designated hospital beds in Maryland.

<b>Description</b>
The MD COVID-19 - Total Currently Hospitalized - Acute and ICU data layer is a collection of the statewide cumulative total of individuals who tested positive for COVID-19 that have been reported each day via CRISP as currently occupying a COVID-19 bed in a Maryland hospital facility. MD COVID-19 - Total Currently Hospitalized comprises four subsets: Adult Acute Care Beds, Adult ICU Beds Pediatrics Acute Care Beds and Pediatrics ICU Care Beds.
Open antero-lateral dislocation of the elbow. A case report

Background
          Open dislocations are infrequent, often associated with damage to the neuro vascular structures. We present an unusual case of an open antero-lateral dislocation of the elbow, which was not associated with any vascular or neural injury.
        
        
          Case presentation
          A 34 year female dance instructor sustained an open dislocation of her elbow. Surgical exploration was undertaken. No major neurovascular injury was present. There was almost complete disruption of all the muscular and ligamentous attachments to the distal humerus and the proximal radius and ulna, which were not formally repaired during surgery. The elbow was found to be very unstable, and was placed in a back slab. The functional recovery was complete in about six months, the patient regaining full range of elbow movement. Elbow dislocations without associate fractures are adequately treated by manipulation and reduction, in spite of the almost complete disruption of the soft tissues around the joint.
Compound 526838: 9-Hydroxy-palmitic acid, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 9-[tert-butyl(dimethyl)silyl]oxyhexadecanoate. Molecular Formula: C23H48O3Si. Molecular Weight: 400.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529318: Oxetane, 3-methyl-3-(1,1-dimethylethyl)

Chemical compound data from PubChem database. IUPAC Name: 3-tert-butyl-3-methyloxetane. Molecular Formula: C8H16O. Molecular Weight: 128.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2010 State Profile — Louisiana

This state profile includes data from facilities in Louisiana that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Louisiana. In Louisiana, 154 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 13,469 clients in substance abuse treatment on March 31, 2010. The survey response rate in Louisiana was 90.9%.
Compound 528619: Cyclopropanecarboxylic acid tert-butylamide

Chemical compound data from PubChem database. IUPAC Name: N-tert-butylcyclopropanecarboxamide. Molecular Formula: C8H15NO. Molecular Weight: 141.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Characteristics of Criminal Justice System Referrals Discharged from Substance Abuse Treatment and Facilities with Specially Designed Criminal Justice Programs

This CBHSQ short report uses data from the 2011 Treatment Episode Data Set – Discharges (TEDS-D) and the 2012 National Survey of Substance Abuse Treatment Services (N-SSATS) to provide a portrait of treatment discharges among those referred to treatment by the criminal justice system, hereafter referred to as criminal justice discharges.
Compound 526648: 2,3',4,4'-Tetrachloro-5-methyl-diphenylmethane

Chemical compound data from PubChem database. IUPAC Name: 1,4-dichloro-2-[(3,4-dichlorophenyl)methyl]-5-methylbenzene. Molecular Formula: C14H10Cl4. Molecular Weight: 320.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525574: N,N-Dimethyl-N'-(3-methoxyphenyl)-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-chloro-N'-(3-methoxyphenyl)-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H17ClN2O. Molecular Weight: 288.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526434: 6-Methyl-1,3-dichlorodibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,3-dichloro-6-methyldibenzofuran. Molecular Formula: C13H8Cl2O. Molecular Weight: 251.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Low agreement for assessing the risk of postoperative deep venous thrombosis when deciding prophylaxis strategies: a study using clinical vignettes

Background
          Several clinical practice guidelines (CPG) on antithrombotic prophylaxis in surgical patients help to decide about the prophylaxis strategy based on the patient risk of deep venous thrombosis (DVT). However, the physician risk estimates of DVT could have little inter-observer reproducibility, which could lead to different individual prophylaxis practices.
        
        
          Methods
          Physicians were asked to evaluate DVT risk in eight clinical vignettes, describing actual patients cared for in our hospital. The vignettes included all possible levels of DVT risk.
        
        
          Results
          The degree of prophylaxis strategies accuracy was 63% (95% CI 523–75%). Overall agreement was 0.32 (z = 7.61, p < 0.001) and for each level of risk kappa was 0.38 (z = 6.50, p < 0.001); 0.1 (z = 1.65, p < 0.049) and 0.5 (z = 8.45, p < 0.001) for small, moderate and high risk group respectively
        
        
          Conclusions
          Our results showed that there is poor agreement when physicians have to evaluate the risk for postoperative DVT, and in the cases of low and moderate risks of DVT there is the smallest agreement. In addition, the data also showed that the overall accuracy of DVT prophylaxis strategy was only moderate and the risk evaluation did not correlate to the selection of the strategy. The issue of inter-observers variability should be taken into account when CPG performance are analysed, especially when considering the risk-evaluation to choose the appropriate actions.
Compound 530707: 5-Bromovaleric acid, 2-methyloct-5-yn-4-yl ester

Chemical compound data from PubChem database. IUPAC Name: 2-methyloct-5-yn-4-yl 5-bromopentanoate. Molecular Formula: C14H23BrO2. Molecular Weight: 303.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2015 CMHS Uniform Reporting System (URS) Table for Wisconsin

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Wisconsin.  The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 526869: 2-(2-(2-Isobutoxy-ethoxy)-ethoxy)-ethoxy)-ethyl acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-(2-methylpropoxy)ethoxy]ethoxy]ethoxy]ethyl acetate. Molecular Formula: C14H28O6. Molecular Weight: 292.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525576: N,N-Dimethyl-N'-(3-methoxyphenyl)-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(3-methoxyphenyl)-N,N,4-trimethylbenzenecarboximidamide. Molecular Formula: C17H20N2O. Molecular Weight: 268.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Distal protection devices during percutaneous coronary and carotid interventions

Distal embolization of particulate matter complicates percutaneous coronary and peripheral interventions more often than had been recognized until recently. A number of distal protection devices are under development. The PercuSurge GuardWire™ is a balloon occlusion thrombectomy device approved by the United States Food and Drug Administration for saphenous vein graft intervention. A number of filter devices utilize an expandable filter mounted on the angioplasty guidewire to facilitate entrapment of particles and safe removal. The Parodi Anti-Emboli System™ is an example of a catheter occlusion device that establishes protection by reversing blood flow in the target vessel.
Oxycodone hydrochloride

Oxycodone Hydrochloride is a prescription opioid medication used to manage moderate to severe pain. Manufactured by Rhodes Pharmaceuticals L.P., it comes in oral tablet form with strengths of 5mg, 10mg, 15mg, 20mg, and 30mg. As a Schedule II controlled substance, it has a high potential for abuse and dependence. This information was generated using AI and is provided for informational and research purposes only.
Heat stress is associated with decreased lactic acidemia in rat sepsis

Background:
          Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury and mortality. We investigated whether heat stress resulted in decreased plasma lactate concentration and protected the lung by decreasing the inflammatory response to sepsis.
        
        
          Results:
          Plasma lactate concentration was elevated in septic rats without prior heat stress. Lactic acid levels were significantly lower in heat-treated septic rats (P < 0.05) and were not significantly different when compared with control rats. Septic rats with or without heat pretreatment had significantly higher myeloperoxidase activity in the lung than did control groups. Heat pretreatment did not prevent neutrophil infiltration or inflammatory mediator production in the lung.
        
        
          Conclusion:
          Prior heat stress ameliorates lactic acidemia in rat sepsis. Heat stress did not attenuate the pulmonary inflammatory process. The mechanism of heat-induced protection from lactic acidemia in sepsis needs to be further explored.
Hydrocodone bitartrate and acetaminophen

Hydrocodone Bitartrate and Acetaminophen is a prescription tablet combining an opioid pain reliever (hydrocodone 5 mg) with acetaminophen (300 mg) for moderate to severe pain. Manufactured by Amneal Pharmaceuticals LLC, it's a Schedule II controlled substance, orally administered, and was marketed starting January 2015 but is now discontinued. This information was generated using AI and is provided for informational and research purposes only.
Compound 525865: N,N-Dimethyl-2-phenyl-N'-nonyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-nonyl-2-phenylethanimidamide. Molecular Formula: C19H32N2. Molecular Weight: 288.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401727-T1: [Translated] ATTENDANCE AND NOTIFICATION SYSTEM TO KEEP AND COMMUNICATE INFORMATION

In accordance with one aspect, a client device is sent an indication of one or more types of information available for the client device. In response to the indication, a request is received from the client device to retrieve the information available for the client device. The information is identified and sent to the client device. In accordance with another aspect, one or more friends of the user are identified from persistent data, and a check made as to whether each of them is logged in to the system. For each of them that is logged in to the system, the user is subscribed to the friend's information and the friend is subscribed to the user's information. In accordance with another aspect, a user is allowed to be a friend of another user only if the other user is also a friend of the user. <IMAGE>
Compound 526792: 3-Hydroxy-heptadecanoic acid, methyl ester, 3-tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 3-[tert-butyl(dimethyl)silyl]oxyheptadecanoate. Molecular Formula: C24H50O3Si. Molecular Weight: 414.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400654-T1: [Translated] NEW MAMMAL GENE BC1-W, WHICH BELONGS TO THE BC1-2 FAMILY OF APOPTOSIS-CONTROLING GENES

The present invention is broadly directed to therapeutic molecules capable of inter alia modulating apoptosis in mammalian cells. The therapeutic molecules of the present invention encompass genetic sequences and chemical entities capable of regulating expression of a novel mammalian gene belonging to the bcl-2 family and which promotes cell survival. The therapeutic molecules of the present invention may have further utility in delaying cell cycle entry. In addition, the present invention extends to chemical entities capable of modulating activity and function of the translation product of said novel gene of the bcl-2 family. The present invention also extends to the translation product of the novel gene of the bcl-2 family and its use in, for example, therapy, diagnosis, antibody generation and as a screening tool for therapeutic molecules capable of modulating physiological cell death or survival and/or modulating cell cycle entry.
Detection of mutations in the dystrophin gene via automated DHPLC screening and direct sequencing

Background
          Currently molecular diagnostic laboratories focus only on the identification of large deletion and duplication mutations (spanning one exon or more) for Duchenne Muscular Dystrophy (DMD) yielding 65% of causative mutations. These mutations are detected by an existing set of multiplexed polymerase chain reaction (PCR) primer pairs. Due to the large size of the dystrophin gene (79 exons), finding point mutations (substitutions, deletions or insertions of one or several nucleotides) has been prohibitively expensive and laborious. The aim of this project was to develop an effective and convenient method of finding all, or most, mutations in the dystrophin gene with only a moderate increase in cost.
        
        
          Results
          Using denaturing high performance liquid chromatography (DHPLC) screening and direct sequencing, 86 PCR amplicons of genomic DNA from the dystrophin gene were screened for mutations in eight patients diagnosed with DMD who had tested negative for large DNA rearragements. Mutations likely to be disease-causative were found in six of the eight patients. All 86 amplicons from the two patients in whom no likely disease-causative mutations were found were completely sequenced and only polymorphisms were found.
        
        
          Conclusions
          We have shown that it is now feasible for clinical laboratories to begin testing for both point mutations and large deletions/duplications in the dystrophin gene. The detection rate will rise from 65% to greater than 92% with only a moderate increase in cost.
Nursing Home Cost Report (RHCF): 2015

The Nursing Home Cost Report (RHCF) is a uniform report completed by New York nursing homes to report income, expenses, assets, liabilities, and statistics to the Department of Health (DOH). Under DOH regulations (Part 86-2.2), nursing homes are required to file financial and statistical data with DOH annually. The data filed is part of the cost report and is received electronically through a secured network. This data is used to develop Medicaid rates, assist in the formulation of reimbursement methodologies, and analyze trends.
Incidence Tables (Standard Errors and P Values) - 4.1 to 4.16

These detailed tables present standard errors for totals and prevalence estimates of substance use initiation from the 2011 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens (including LSD, PCP, Ecstasy), inhalants, and the nonmedical use of prescription-type pain relievers (including OxyContin), tranquilizers, stimulants, sedatives, alcohol, and tobacco products (including cigarettes, smokeless tobacco, and cigars). Standard errors are provided by age group and gender. Standard errors are provided for both 2011 and 2010.