AndreaBozzo/ceres-open-data-index huggingface dataset:
Washington, D.C., and the Local Child Welfare Professional

How does the Federal Government stay connected to the needs and issues of the frontlines of child welfare?

How is the field changing its approach to protecting children and strengthening families?

Find out the answers to these questions and more in this podcast, "Washington, D.C., and the Local Child Welfare Professional", featuring a conversation with Rafael López, who was nominated by the President and confirmed by the Senate in 2015 as the Commissioner of the Administration on Children, Youth and Families within the U.S. Department of Health and Human Services. Commissioner López’s experience spans the local, State, and Federal levels of child welfare.

In this podcast, Commissioner López shares his insights and passions regarding the following:

Follow the Office of the Commissioner on Twitter
  
  

 (@ACYFgov).

Runtime: 40:28

Metadata-only record linking to the original dataset. Open original dataset below.
Delta-opioid receptor endocytosis in spinal cord after dermenkephalin activation

Background
          The delta(δ)-opioid receptors belong to the G protein-coupled receptors and in vitro studies have shown that δ-opioid receptors undergo an internalization process in response to agonist stimulation. The immediate consequence is the disappearance of receptors from the plasma membrane. This adaptation process reveals the cell's capacity to desensitize after a strong agonist stimulus. This process, if it occurs in vivo, could contribute to the tolerance phenomenon observed after opiate treatment. To study the mechanisms underlying regulation of the δ-opioid receptors in vivo, the effects of an application of the drug dermenkephalin, a potent and selective agonist of the δ-opioid receptor, were analysed in the rat spinal cord.
        
        
          Results
          Using immunocytochemistry and electron microscopy, we observed in control rats that membrane labelling was strictly localized at the interface between two neurites. Fifteen minutes after dermenkephalin stimulation, the plasma membrane labelling was associated with invaginated areas. Thirty minutes after stimulation, labelled vesicles were found in the cytoplasm confirming the internalization process.
        
        
          Conclusions
          The present findings support the view that δ-opioid receptors are internalized in response to prolonged exposure to dermenkephalin in vivo and confirm the presynaptic localization of δ-opioid receptors in the dorsal horn of the rat spinal cord.
National Youth Survey US:  Wave III (NYS-1978)

<p>Youth data for the third wave of the National Youth Survey<br />
are contained in this data collection, which includes data for youth<br />
interviewed in 1979 about events and behavior of the preceding year.<br />
The first wave of this study was conducted in 1976 and the<br />
second wave in 1977. Data were collected on the<br />
demographic and socioeconomic status of respondents, disruptive events<br />
in the home, youth aspirations, expectations for future goals, social<br />
isolation, normlessness, labeling, perceived disapproval, attitudes<br />
toward deviance, exposure and commitment to delinquent peers, sex<br />
roles, attitudes toward sexual assault, interpersonal violence,<br />
pressure for substance abuse by peers, exposure to substance abuse by<br />
parents, self-reported delinquency, and drug and alcohol use.This study has 1 Data Set.</p>
Compound 525837: N,N-Dimethyl-N'-butyl-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N'-butyl-N,N-dimethylpropanimidamide. Molecular Formula: C9H20N2. Molecular Weight: 156.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525511: 8-Methyl-4,5-dithia-1-nonene

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-1-(prop-2-enyldisulfanyl)butane. Molecular Formula: C8H16S2. Molecular Weight: 176.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Genomic approaches to research in lung cancer

The medical research community is experiencing a marked increase in the amount of information available on genomic sequences and genes expressed by humans and other organisms. This information offers great opportunities for improving our understanding of complex diseases such as lung cancer. In particular, we should expect to witness a rapid increase in the rate of discovery of genes involved in lung cancer pathogenesis and we should be able to develop reliable molecular criteria for classifying lung cancers and predicting biological properties of individual tumors. Achieving these goals will require collaboration by scientists with specialized expertise in medicine, molecular biology, and decision-based statistical analysis.
Compound 526000: (17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl) hexadecanoate

Chemical compound data from PubChem database. IUPAC Name: (17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl) hexadecanoate. Molecular Formula: C37H62O3. Molecular Weight: 554.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Predictors of positive health in disability pensioners: a population-based questionnaire study using Positive Odds Ratio

Background
          Determinants of ill-health have been studied far more than determinants of good and improving health. Health promotion measures are important even among individuals with chronic diseases. The aim of this study was to find predictors of positive subjective health among disability pensioners (DPs) with musculoskeletal disorders.
        
        
          Methods
          Two questionnaire surveys were performed among 352 DPs with musculoskeletal disorders. Two groups were defined: DPs with positive health and negative health, respectively. In consequence with the health perspective in this study the conception Positive Odds Ratio was defined and used in the logistic regression analyses instead of the commonly used odds ratio.
        
        
          Results
          Positive health was associated with age ≥ 55 years, not being an immigrant, not having fibromyalgia as the main diagnosis for granting an early retirement, no regular use of analgesics, a high ADL capacity, a positive subjective health preceding the study period, and good quality of life.
        
        
          Conclusion
          Positive odds ratio is a concept well adapted to theories of health promotion. It can be used in relation to positive outcomes instead of risks. Suggested health promotion and secondary prevention efforts among individuals with musculoskeletal disorders are 1) to avoid a disability pension for individuals <55 years of age; if necessary, to make sure rehabilitation actions continue, 2) to increase efforts to support immigrants to adjust to circumstances connected to ill-health and retirement, 3) to pay special attention to individuals with fibromyalgia and other general pain disorders, and 4) to strengthen ADL activities to support an independent active life among disability pensioners.
Compound 525695: p-Methoxybenzylidene-(3-ethoxyphenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: N-(3-ethoxyphenyl)-1-(4-methoxyphenyl)methanimine. Molecular Formula: C16H17NO2. Molecular Weight: 255.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400189-T1: [Translated] DELIVERY OF DISEASE CONTROL AGENTS IN AQUACULTURE USING YEAST CONTAINING BIOACTIVE PROTEINS

This invention is directed to the use of fungal cells which are used as feed components in aquaculture or agriculture, and which also contain exogenous peptides, proteins, and/or antibodies, which will convey resistance or immunity to viral or bacterial pathogens or otherwise improve the health and performance of the species consuming said fungal cells.
Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid  arthritis - studies in mice and men

Inherited susceptibility to rheumatoid arthritis (RA) is associated			 with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1			 molecules. Transgenic mice expressing these major histocompatibility complex			 (MHC) class II molecules have been developed to generate humanized models for			 RA. The relevance of these models for understanding RA will be discussed.
Compound 529084: (RS)-Naproxen methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(6-methoxynaphthalen-2-yl)propanoate. Molecular Formula: C15H16O3. Molecular Weight: 244.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526589: 2,6-Bis-(2-hydroxy-5-methyl-benzyl)-4-methyl-phenol, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[4-methyl-2,6-bis[(5-methyl-2-trimethylsilyloxyphenyl)methyl]phenoxy]silane. Molecular Formula: C32H48O3Si3. Molecular Weight: 565.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
21st European Workshop for Rheumatology Research, Vienna, Austria, 1–4 March 2001

Major advances in technology now drive how we approach questions in immunology, particularly in analyzing complex data sets commonly encountered in genomics and proteomics studies. Active areas of investigation include development of novel technologies, identification of elusive target antigens for RA and other diseases, dissection of signaling pathways connecting the lymphocyte cell surface with the nucleus, and exploration of new avenues for therapeutic interventions. The European Workshop for Rheumatology Research (EWRR) is a forum for many European and non-European scientists to present research findings of high quality. Arthritis researchers from around the globe should be strongly encouraged to attend future meetings, the next of which is the 22nd EWRR meeting in Leiden, the Netherlands, in 2002.
Compound 529890: 2-Methyl-6-(4-methylcyclohex-3-en-1-yl)hepta-2,6-dien-1-ol

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-6-(4-methylcyclohex-3-en-1-yl)hepta-2,6-dien-1-ol. Molecular Formula: C15H24O. Molecular Weight: 220.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528717: 1-(Prop-1-enyltetrasulfanyl)propane

Chemical compound data from PubChem database. IUPAC Name: 1-(prop-1-enyltetrasulfanyl)propane. Molecular Formula: C6H12S4. Molecular Weight: 212.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2009-2010 NSDUH State Estimates of Substance Use and Mental Disorders

This page presents the tables of State-specific tables of State estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Results are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Annual Report to Congress on State Child Welfare Expenditures reported on the CFS-101 (2016)

This report to Congress provides national totals of planned spending by service category for the Stephanie Tubbs Jones Child Welfare Services program and planned and actual spending by service category for the Promoting Safe and Stable Families program.

For questions on Attachments A and B, please contact Linda Viales at Linda.Viales@acf.hhs.gov for assistance.

Metadata-only record linking to the original dataset. Open original dataset below.
Early peri-operative hyperglycaemia and renal allograft rejection in patients

Background
          Patients with diabetes have an increased risk for allograft rejection, possibly related to peri-operative hyperglycaemia. Hyperglycaemia is also common following transplantation in patients without diabetes. We hypothesise that exposure of allograft tissue to hyperglycaemia could influence the risk for rejection in any patient with high sugars. To investigate the relationship of peri-operative glucose control to acute rejection in renal transplant patients without diabetes, all patients receiving their first cadaveric graft in a single center were surveyed and patients without diabetes receiving cyclosporin-based immunosuppression were reviewed (n = 230). Records of the plasma blood glucose concentration following surgery and transplant variables pertaining to allograft rejection were obtained. All variables suggestive of association were entered into multivariate logistic regression analysis, their significance analysed and modeled.
        
        
          Results
          Hyperglycaemia (>8.0 mmol/L) occurs in over 73% of non-diabetic patients following surgery. Glycaemic control immediately following renal transplantation independently predicted acute rejection (Odds ratio=1.08). 42% of patients with a glucose < 8.0 mmol/L following surgery developed rejection compared to 71% of patients who had a serum glucose above this level. Hyperglycaemia was not associated with any delay of graft function.
        
        
          Conclusion
          Hyperglycaemia is associated with an increased risk for allograft rejection. This is consistent with similar findings in patients with diabetes. We hypothesise a causal link concordant with epidemiological and in vitro evidence and propose further clinical research.
Compound 527783: Benzoic acid, 2-chloro, 2-methyl-3-butenyl ester

Chemical compound data from PubChem database. IUPAC Name: pent-4-en-2-yl 2-chlorobenzoate. Molecular Formula: C12H13ClO2. Molecular Weight: 224.68. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Miami - Dade Div: Drug-Related Emergency Department Visits, 2004-2011 - Seeking Detox

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving patients seeking detox in the Dade County division of the Miami metropolitan area, covering 2004-2011. This includes nonemergency requests made through the ED for admission to detoxification unit, visits to obtain medical clearance before being incarcerated, and acute emergencies where an individual is experiencing withdrawal symptoms and requests detox. These estimates do not include patients who seek or enter the hospital\'s detox unit through other avenues.
NNDSS - Table II. Hepatitis (viral, acute) C

NNDSS - Table II. Hepatitis (viral, acute) C - 2017. In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed.  The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories.

Note:
These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. 

Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. 

Footnotes:
 C.N.M.I.: Commonwealth of Northern Mariana Islands. 

 U: Unavailable. —: No reported cases. N: Not reportable. NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum. 

 *Three low incidence conditions, rubella, rubella congenital, and tetanus, are in Table II to facilitate case count verification with reporting jurisdictions. 

† Case counts for reporting year 2017 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for tuberculosis are displayed in Table IV, which appears quarterly.

§ Based on the CSTE Position Statement 15-ID-03: Revision of the Case Definition of Hepatitis C for National Notification, acute hepatitis C is now reported by case classification status.
Compound 530336: Methyl docosa-7,10,13,16,19-pentaenoate

Chemical compound data from PubChem database. IUPAC Name: methyl docosa-7,10,13,16,19-pentaenoate. Molecular Formula: C23H36O2. Molecular Weight: 344.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526015: m-Synephrine, DTFMB-TMS

Chemical compound data from PubChem database. IUPAC Name: N-methyl-3,5-bis(trifluoromethyl)-N-[2-trimethylsilyloxy-2-(3-trimethylsilyloxyphenyl)ethyl]benzamide. Molecular Formula: C24H31F6NO3Si2. Molecular Weight: 551.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530481: 5-Chlorovaleric acid, 1-adamantylmethyl ester

Chemical compound data from PubChem database. IUPAC Name: 1-adamantylmethyl 5-chloropentanoate. Molecular Formula: C16H25ClO2. Molecular Weight: 284.82. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401121-T1: [Translated] MOVEMENT ELEMENT FOR SMALL QUANTITIES OF LIQUID

The invention relates to a motion element for producing motion in small quantities of liquid comprising a plate-shaped member having two principal surfaces, wherein at least one motion device, which is electrically controllable, is arranged on a first active principal surface to set in motion a liquid which is in contact with the active principal surface, and electrical contact elements for the motion device. The invention furthermore relates to a motion device which can be used with the motion element according to the invention, a cartridge to receive a motion element according to the invention, a reaction device to receive a cartridge according to the invention and a method for producing motion in small quantities of liquid.
Mosunetuzumab

Lunsumio (mosunetuzumab) is a prescription monoclonal antibody made by Genentech, Inc., used to treat certain types of follicular lymphoma in adults who have relapsed or not responded to other treatments. It's administered as an intravenous injection, available in concentrate forms like 1 mg/mL or 30 mg/30 mL vials. This information was generated using AI and is provided for informational and research purposes only.
Patent AT-E399567-T1: [Translated] PEG CONJUGATES OF LHRH ANALOGUE

PEG-LHRH analog conjugates, where a PEG moiety is covalently bound to a serine residue of a LHRH analog, and methods for producing these conjugates are provided in the present invention. Also provided are a pharmaceutical composition and a method for treating pathologies in which LHRH analog administration is beneficial.
Compound 528466: 1-Tridecene, 3,7,11-trimethyl

Chemical compound data from PubChem database. IUPAC Name: 3,7,11-trimethyltridec-1-ene. Molecular Formula: C16H32. Molecular Weight: 224.42. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Submission of the first APSR to the 2025-2029 CFSP, CAPTA State Plan update, and the CFS-101 Part 1, Annual Budget Request, Part 2, Annual Summary of the CFS, and Part 3, Annual Expenditure Report

This Program Instruction (PI) provides guidance to states, territories, and insular areas (hereafter “states,” unless otherwise noted) on actions required to receive Federal Fiscal Year (FY) 2026 allotments (subject to the availability of appropriations) under the formula grant programs authorized by title IV-B, subparts 1 and 2, section 106 of CAPTA, and the Chafee and ETV programs.

This PI summarizes requirements for completing and submitting: (1) the first APSR update to the 2025-2029 CFSP, (2) the CAPTA State Plan update, and (3) the CFS-101, Parts I, II, and III.

PI-25-01 (PDF)

For the best access to each attachment, please download and save them to your computer.

FY 2024 Allotment for Title IV-B, Subpart 1 Stephanie Tubbs Jones Child Welfare Services GrantsFY 2024 Allotment for Title IV-B, Subpart 2 Promoting Safe and Stable Families GrantsFY 2024 Allotment for Title IV-B, Subpart 2 Monthly Caseworker Visit GrantsFY 2024 Allotment for Title IV-B, Subpart 2 Kinship Navigator GrantsFY 2024 Allotment for Chafee Foster Care Program for Successful Transition to Adulthood GrantsFY 2024 Allotment for Education and Training Vouchers GrantsFY 2024 Allotment for CAPTA State GrantsFY 2021 ARPA Supplemental Allotment for CAPTA State GrantsFY 2020 Allotment for Family First Prevention Services Act Transition Grants

CFS-101 Instructions, Part I, II, and III (PDF)

IntroductionPart I: Annual Budget Request for Funds under Title IV-B, Subparts 1 & 2, CAPTA State Grant, Chafee, and ETVPart II: Annual Estimated Expenditure Summary of Child and Family Services Funds Part III: Expenditures for Title IV-B, Subparts 1 and 2, John H. Chafee Foster Care Program for Successful Transition to Adulthood, and Education and Training Voucher (ETV) Program

CFS-101 Forms, Parts I, II and III Excel Workbook (XLSX)

Annual Reporting of Education and Training Vouchers Awarded (PDF)

Metadata-only record linking to the original dataset. Open original dataset below.
Patent AT-E399979-T1: [Translated] METHOD AND DEVICE FOR AIDING CONTROL IN AN AIRPLANE

Pilot assistance method in which a first symbol indicative of an aircraft velocity vector is displayed on a visualization screen. According to the method at least one further indicative symbol is displayed on the screen that is associated with the first symbol and indicates the longitudinal margin for maneuver. The margin for maneuver is expressed as a load factor and is relative to either diving or climbing aircraft maneuvers.  An Independent claim is made for a device, such as a head up display, for presentation of aircraft velocity vector and another symbol relating to the margin for maneuver in terms of stalls brought on by diving or climbing.