AndreaBozzo/ceres-open-data-index huggingface dataset:
Transcriptional regulation of lung development: emergence of specificity

The lung is the product of a set of complex developmental interactions between two distinct tissues, the endodermally derived epithelium and the mesoderm. Each tissue contributes to lung development by fine-tuning the spatial and temporal pattern of gene expression for a distinct array of signaling molecules, transcriptional molecules and molecules related to the extracellular matrix. Morphoregulatory transcriptional factors such as NKX2.1 have the crucial role of connecting the cell–cell crosstalk to the activation or repression of gene expression through which processes such as cellular proliferation, migration, differentiation and apoptosis can be controlled. Although none of the factors participating in lung development are exclusively lung-specific, their unique combinations and interactions constitute the basis for emergence of lung structural and functional specificities. An understanding of the individual molecules and their unique interactions in the context of lung development is necessary for the construction of a morphogenetic map for this vital organ as well as for the development of rational and innovative approaches to congenital and induced lung disease.
Mouse pulmonary response following solid surface composite dust inhalation

Solid surface composites (SSCs) are a widely used construction material that can generate dust and volatile organic chemicals (VOCs) during fabrication. Exposure to SSC dust has been linked to pulmonary health effects, including pulmonary fibrosis and lung inflammation. Previous studies have investigated the toxicity of SSC particles using in vitro and in vivo models, but these studies have limitations. For example, they often relied on pre-generated particles that may not accurately represent the size distribution and characteristics of aerosols encountered in real-world settings. Additionally, these models did not capture the co-exposure to VOCs that can occur during SSC fabrication.
To address these limitations, we developed a novel apparatus capable of real-time generation of SSC sawing particles and their simultaneous delivery to rodents via whole-body inhalation. This approach allows for a more accurate assessment of SSC toxicity under conditions that better reflect workplace exposure scenarios. The present study utilizes this system to characterize the acute pulmonary response in mice following a 4-day inhalation exposure to real-time generated SSC aerosols, with evaluations at 1, 6, 27, and 56 days post-exposure.
Compound 530595: 4-Cyanobenzoic acid, 2-adamantyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-adamantyl 4-cyanobenzoate. Molecular Formula: C18H19NO2. Molecular Weight: 281.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2010 State Profile — Nevada

This state profile includes data from facilities in Nevada that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Nevada. In Nevada, 84 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 7,041 clients in substance abuse treatment on March 31, 2010. The survey response rate in Nevada was 95.6%.
Compound 529485: Ethyl 1-(1,1-dioxido-1,2-benzisothiazol-3-yl)-4-piperidinecarboxylate

Chemical compound data from PubChem database. IUPAC Name: 3-hydroxy-6-methyl-2,3-dihydropyran-4-one. Molecular Formula: C6H8O3. Molecular Weight: 128.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Provisional Death Counts for Coronavirus Disease (COVID-19)

This dataset is no longer updated.  Please see the following datasets for recent data:

Provisional COVID-19 Deaths by Week (https://data.cdc.gov/dataset/Provisional-COVID-19-Death-Counts-by-Week-Ending-D/r8kw-7aab/)

Provisional COVID-19 Deaths by Sex, Age, and State (https://data.cdc.gov/NCHS/Provisional-COVID-19-Death-Counts-by-Sex-Age-and-S/9bhg-hcku)
Compound 525597: N,N-Dimethyl-N'-(4-ethoxyphenyl)-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-ethoxyphenyl)-N,N,4-trimethylbenzenecarboximidamide. Molecular Formula: C18H22N2O. Molecular Weight: 282.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Research Article: Arthritis Research

Wegener's granulomatosis (WG) is a form of systemic vasculitis. It is characterized by granulomatous inflammation in the upper and lower airways, vasculitis and necrotizing glomerulonephritis, and is strongly associated with antineutrophil cytoplasmic antibodies against proteinase 3. Since the etiology of the disease is not clear, treatment, consisting of corticosteroids and immunosuppressives, is nonspecific and associated with severe side effects. Pinpointing the trigger(s) of the disease would highly improve treatment. Clinical evidence shows that an infectious agent, the bacterium Staphylococcus aureus, is a risk factor for disease relapse, suggesting its involvement in the pathogenesis of WG. Here we review both clinical and experimental data that either indicate or support a role for S. aureus in WG.
Compound 528343: Benzoic acid, 3-chloro-2-hydroxy, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 3-chloro-2-trimethylsilyloxybenzoate. Molecular Formula: C13H21ClO3Si2. Molecular Weight: 316.92. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Comparative mutational analysis
 of

Human immunodeficiency virus type 1 (HIV-1) and human T cell
 leukemia virus type II (HTLV-2) use a similar mechanism for –1
 translational frameshifting to overcome the termination codon in
 viral RNA at the end of the gag gene. Previous
 studies have identified two important RNA signals for frameshifting,
 the slippery sequence and a downstream stem–loop structure.
 However, there have been somewhat conflicting reports concerning
 the individual contributions of these sequences. In this study we
 have performed a comprehensive mutational analysis of the cis-acting
 RNA sequences involved in HIV-1 gag–pol and HTLV-2 gag–pro frameshifting. Using an in vitro translation
 system we determined frameshifting efficiencies for shuffled HIV-1/HTLV-2
 RNA elements in a background of HIV-1 or HTLV-2 sequences. We show
 that the ability of the slippery sequence and stem–loop
 to promote ribosomal frameshifting is influenced by the flanking
 upstream sequence and the nucleotides in the spacer element. A wide
 range of frameshift efficiency rates was observed for both viruses
 when shuffling single sequence elements. The results for HIV-1/HTLV-2
 chimeric constructs represent strong evidence supporting the notion
 that the viral wild-type sequences are not designed for maximal
 frameshifting activity but are optimized to a level suited to efficient
 viral replication.
Compound 525283: Ethanimidamide, N,N-dimethyl-N'-pentyl-

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-pentylethanimidamide. Molecular Formula: C9H20N2. Molecular Weight: 156.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529176: 1-Pentanol, 5-amino, N-isopropylidene

Chemical compound data from PubChem database. IUPAC Name: 5-(propan-2-ylideneamino)pentan-1-ol. Molecular Formula: C8H17NO. Molecular Weight: 143.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528906: 3,3-Diethyl-5-methyl-2,4,6-piperidinetrione

Chemical compound data from PubChem database. IUPAC Name: 3,3-diethyl-5-methylpiperidine-2,4,6-trione. Molecular Formula: C10H15NO3. Molecular Weight: 197.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400352-T1: [Translated] PRODUCTION OF POLYMER OBJECTS WITH HYDROPHILIC SURFACE

Polymeric articles, including membranes, with surfaces having a desired chemical functionality are created by surface segregation of a branched component blended with a compatible, matrix base component, the branched component having the desired chemical functionality. In particular, hydrophilic surfaces are created via surface segregation of a branched hydrophilic copolymer blended into a polymer matrix. The use of branched molecular architecture provides a thermodynamic mechanism for the segregation of the hydrophilic species to the surface and a means for achieving a high surface coverage of the hydrophilic moiety. The branched hydrophilic copolymer can be defined by a random copolymer including two or more methacrylate or acrylate monomers, at least one of which features a short hydrophilic side chain, such as a polyethylene glycol side chain. The branched hydrophilic copolymer is compatible, and well-entangled, with the acrylate polymer matrix.
Compound 526428: 3-Ethyl-3,4,5-trimethylheptane

Chemical compound data from PubChem database. IUPAC Name: 3-ethyl-3,4,5-trimethylheptane. Molecular Formula: C12H26. Molecular Weight: 170.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The measurement of lung water

Introduction:
          In this review, we compare the spectrum of currently available				methods for quantifying pulmonary edema in patients.
        
        
          Review:
          Imaging and indicator dilution techniques comprise the most common				strategies for measuring lung water at the bedside. The most accurate (within				10% of the gravimetric gold standard) and most reproducible (< 5%				between-test variation) are also, unfortunately, the most expensive and most				difficult to implement for purposes of large-scale clinical trials or for				routine clinical practice.
        
        
          Conclusion:
          The standard chest radiograph remains the best screening test for				the detection of pulmonary edema. Indicator-dilution techniques are probably				the best available method at present for quantitation in patient groups.
Compound 529143: Silane, (decyloxy)(1,1-dimethylethyl)dimethyl-

Chemical compound data from PubChem database. IUPAC Name: tert-butyl-decoxy-dimethylsilane. Molecular Formula: C16H36OSi. Molecular Weight: 272.54. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
A model combining cell physiology and population genetics to explain

Background
          Laboratory experiments under controlled conditions during thousands of generations are useful tools to assess the processes underlying bacterial evolution. As a result of these experiments, the way in which the traits change in time is obtained. Under these conditions, the bacteria E. coli shows a parallel increase in cell volume and fitness.
        
        
          Results
          To explain this pattern it is required to consider organismic and population contributions. For this purpose we incorporate relevant information concerning bacterial structure, composition and transformations in a minimal modular model. In the short time scale, the model reproduces the physiological responses of the traits to changes in nutrient concentration. The decay of unused catabolic functions, found experimentally, is introduced in the model using simple population genetics. The resulting curves representing the evolution of volume and fitness in time are in good agreement with those obtained experimentally.
        
        
          Conclusions
          This study draws attention on physiology when studying evolution. Moreover, minimal modular models appear to be an adequate strategy to unite these barely related disciplines of biology.
The Federal Parent Locator Service

The Federal Parent Locator Service (FPLS), a service operated by the Office of Child Support Services (OCSS), may be accessed by state child welfare agencies to locate and notify parents and other relatives of a child placed in foster care. The FPLS may also be used to locate youth who have exited foster care to provide services or for purposes of completing the National Youth in Transition Database (NYTD) survey. CB and OCSE jointly published an Information Memorandum (ACYF-CB-IM-12-06) that discusses the FPLS, child support information available to state child welfare agencies, and related topics.

State child welfare agencies may request FPLS information several ways including:

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 527309: Diflunisal di-methyl derivative

Chemical compound data from PubChem database. IUPAC Name: methyl 5-(2,4-difluorophenyl)-2-methoxybenzoate. Molecular Formula: C15H12F2O3. Molecular Weight: 278.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529175: 1-Pentanamine, N-isopropylidene

Chemical compound data from PubChem database. IUPAC Name: N-pentylpropan-2-imine. Molecular Formula: C8H17N. Molecular Weight: 127.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525875: N,N-Dimethyl-N'-(3-ethoxyphenyl)-pivalamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(3-ethoxyphenyl)-N,N,2,2-tetramethylpropanimidamide. Molecular Formula: C15H24N2O. Molecular Weight: 248.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526893: 2-(2-Isobutoxyethoxy)ethyl acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-(2-methylpropoxy)ethoxy]ethyl acetate. Molecular Formula: C10H20O4. Molecular Weight: 204.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - TABLE 1OO. Viral hemorrhagic fevers, Machupo virus to Viral hemorrhagic fevers, Sabia virus

NNDSS - TABLE 1OO. Viral hemorrhagic fevers, Machupo virus to Viral hemorrhagic fevers, Sabia virus – 2020. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Note:
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html.

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2019 and 2020 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
§ Prior to 2015, CDC's National Notifiable Diseases Surveillance System (NNDSS) did not receive electronic data about incident cases of specific viral hemorrhagic fevers; instead data were collected in aggregate as "viral hemorrhagic fevers". NNDSS was updated beginning in 2015 to receive data for each of the viral hemorrhagic fevers listed.
Compound 530785: 4-Cyanobenzoic acid, 2-bromo-4-fluorophenyl ester

Chemical compound data from PubChem database. IUPAC Name: (2-bromo-4-fluorophenyl) 4-cyanobenzoate. Molecular Formula: C14H7BrFNO2. Molecular Weight: 320.11. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Child Abuse Prevention Services in San Francisco

Contains information on child abuse prevention services provided by multiple departments within the City and County of San Francisco, including services run directly by City departments and programs provided by contracted organizations. Information was collected by the Controller’s Office as a first step in creating a county-wide abuse prevention plan, and includes program descriptions, cost information (where available), and categorizations by service area, protective factor, target audience, and level of prevention. This data was originally collected in FY19 for programs run during FY18. For more information please see the Controller's report at http://openbook.sfgov.org/webreports/details3.aspx?id=2778
Patent AT-E401531-T1: [Translated] LAMP

The light has a light body (5) and a bearer arm (2) that carries the body on one end and is connected to a base part (8) at the other. The bearer arm has a continuous series of elements (3) joined together by joining linkages (4) and at least one flexible element extending over the linkage at the base and essentially arranged within the element to absorb at least some of the torque acting on the joining linkage at the base when the light is used.
Compound 527437: 3-Mercapto-2-butylpropanal

Chemical compound data from PubChem database. IUPAC Name: 2-(sulfanylmethyl)hexanal. Molecular Formula: C7H14OS. Molecular Weight: 146.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526696: 3,4-di-O-acetyl-1,5-anhydro-2-O-methyl-D-fucitol

Chemical compound data from PubChem database. IUPAC Name: (4-acetyloxy-5-methoxy-2-methyloxan-3-yl) acetate. Molecular Formula: C11H18O6. Molecular Weight: 246.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Colonic tuberculosis mimicking Crohn's disease: case report

Background
          Intestinal tuberculosis is a rare disease in western countries, affecting mainly immigrants and immunocompromised patients. Intestinal tuberculosis is a diagnostic challenge, especially when active pulmonary infection is absent. It may mimic many other abdominal diseases.
        
        
          Case presentation
          Here, we report a case of isolated colonic tuberculosis where the initial diagnostic workup was suggestive of Crohn's disease. Computed tomography findings however, raised the possibility of colonic tuberculosis and the detection of acid-fast bacilli in biopsy specimens confirmed the diagnosis.
        
        
          Conclusions
          In conclusion, this case highlights the need for awareness of intestinal tuberculosis in the differential diagnosis of chronic intestinal disease
2013 CMHS Uniform Reporting System (URS) Tables for Iowa

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Iowa for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Pittsburgh, PA

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Pittsburgh, PA metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for the Pittsburgh metro area, Pennsylvania, and the U.S. overall.
Compound 526827: 14-Hydroxy-nonadecanoic, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 14-[tert-butyl(dimethyl)silyl]oxynonadecanoate. Molecular Formula: C26H54O3Si. Molecular Weight: 442.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Impaired Driving Death Rate, by Age and Sex, 2012 & 2014, Region 8 - Denver

Rate of deaths by age/gender (per 100,000 population) for people killed in crashes involving a driver with BAC =>0.08%, 2012, 2014. 2012 Source: Fatality Analysis Reporting System (FARS). 2014 Source: National Highway Traffic Administration's (NHTSA) Fatality Analysis Reporting System (FARS), 2014 Annual Report File. Note: Blank cells indicate data are suppressed. Fatality rates based on fewer than 20 deaths are suppressed.
Monthly Cumulative Number and Percent of Children <8 Months Who Received Nirsevimab by Jurisdiction, United States

Monthly Cumulative Percent of Children <8 Months Who Received Nirsevimab by Jurisdiction, United States. 
Nirsevimab coverage for children 0 to 7 months is assessed through U.S. jurisdictions’ Immunization Information Systems Resources (IIS) data, submitted from jurisdictions to CDC monthly in aggregate by age group (https://www.cdc.gov/iis/about/).