AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 528297: Pyrazine, 2-(3-methylpentyl)-3-methoxy

Chemical compound data from PubChem database. IUPAC Name: 2-methoxy-3-(3-methylpentyl)pyrazine. Molecular Formula: C11H18N2O. Molecular Weight: 194.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The mechanisms responsible for 2-dimensional pattern formation in bacterial macrofiber populations grown on solid surfaces: fiber joining and the creation of exclusion zones

Background
          When Bacillus subtilis is cultured in a complex fluid medium under conditions where cell separation is suppressed, populations of multicellular macrofibers arise that mature into ball-like structures. The final sedentary forms are found distributed in patterns on the floor of the growth chamber although individual cells have no flagellar-driven motility. The nature of the patterns and their mode of formation are described in this communication.
        
        
          Results
          Time-lapse video films reveal that fiber-fiber contact in high density populations of macrofibers resulted in their joining either by entwining or supercoiling. Joining led to the production of aggregate structures that eventually contained all of the fibers located in an initial area. Fibers were brought into contact by convection currents and motions associated with macrofiber self-assembly such as walking, pivoting and supercoiling. Large sedentary aggregate structures cleared surrounding areas of other structures by dragging them into the aggregate using supercoiling of extended fibers to power dragging. The spatial distribution of aggregate structures in 6 mature patterns containing a total of 637 structures was compared to that expected in random theoretical populations of the same size distributed in the same surface area. Observed and expected patterns differ significantly. The distances separating all nearest neighbors from one another in observed populations were also measured. The average distance obtained from 1451 measurements involving 519 structures was 0.73 cm. These spacings were achieved without the use of flagella or other conventional bacterial motility mechanisms. A simple mathematical model based upon joining of all structures within an area defined by the minimum observed distance between structures in populations explains the observed distributions very well.
        
        
          Conclusions
          Bacterial macrofibers are capable of colonizing a solid surface by forming large multicellular aggregate structures that are distributed in unique two-dimensional patterns. Cell growth geometry governs in an hierarchical way the formation of these patterns using forces associated with twisting and supercoiling to drive motions and the joining of structures together. Joining by entwining, supercoiling or dragging all require cell growth in a multicellular form, and all result in tightly fused aggregate structures.
NNDSS - TABLE 1K. Ehrlichiosis and Anaplasmosis, Anaplasma phagocytophilum infection to Ehrlichia chaffeensis infection

NNDSS - TABLE 1K. Ehrlichiosis and Anaplasmosis, Anaplasma phagocytophilum infection to Ehrlichia chaffeensis infection - 2020. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2019 and 2020 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
NNDSS - Table 1H. Cholera to Coccidioidomycosis

NNDSS - Table 1H. Cholera to Coccidioidomycosis - 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:

•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.

Footnotes:

*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
Quality Payment Program Experience

The Quality Payment Program (QPP) Experience dataset provides participation and performance information in the Merit-based Incentive Payment System (MIPS) during each performance year. They cover eligibility and participation, performance categories, and final score and payment adjustments. The dataset provides additional details at the TIN/NPI level on what was published in the previous performance year. You can sort the data by variables like clinician type, practice size, scores, and payment adjustments.
Compound 530046: 21-Hydroxyprogesterone, trimethylsilyl ether, bis(O-methyloxime)

Chemical compound data from PubChem database. IUPAC Name: N-methoxy-17-[N-methoxy-C-(trimethylsilyloxymethyl)carbonimidoyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-imine. Molecular Formula: C26H44N2O3Si. Molecular Weight: 460.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Early Model-based Provisional Estimates of Drug Overdose, Suicide, and Transportation-related Deaths

This dataset provides model-based provisional estimates of the weekly numbers of drug overdose, suicide, and transportation-related deaths using “nowcasting” methods to account for the normal lag between the occurrence and reporting of these deaths. Estimates less than 10 are suppressed. These early model-based provisional estimates were generated using a multi-stage hierarchical Bayesian modeling process to generate smoothed estimates of the weekly numbers of death, accounting for reporting lags. These estimates are based on several assumptions about how the reporting lags have changed in recent months across different jurisdictions, and the resulting estimates differ from other sources of provisional mortality data.  For now, these estimates should be considered highly uncertain until further evaluations can be done to determine the validity of these assumptions about timeliness. The true patterns in reporting lags will not be known until data are finalized, typically 11–12 months after the end of the calendar year. Importantly, these estimates are not a replacement for monthly provisional drug overdose death counts, or quarterly provisional mortality estimates. For more detail about the nowcasting methods and models, see:

Rossen LM, Hedegaard H, Warner M, Ahmad FB, Sutton PD. Early provisional estimates of drug overdose, suicide, and transportation-related deaths: Nowcasting methods to account for reporting lags. Vital Statistics Rapid Release; no 11. Hyattsville, MD: National Center for Health Statistics. February 2021. DOI: https://doi.org/10.15620/ cdc:101132
Deaths Due to Suicide by Race/Ethnicity, Sex and Age, by Region, New York State: Beginning 2018

This dataset contains the number of New York State deaths due to suicide by jurisdiction, race/ethnicity, age group and sex. The data presented here may differ from the Vital Statistics tables on the Department public website due to data updates. For more information, visit  https://www.health.ny.gov/statistics/vital_statistics/vs_reports_tables_list.htm,  where information from this dataset is presented in tabular form in Table 43.
Fingolimod hydrochloride

Fingolimod Hydrochloride is a generic prescription drug, equivalent to 0.5 mg of fingolimod base per capsule, used orally to treat relapsing forms of multiple sclerosis. Manufactured by Ascend Laboratories, LLC under ANDA208004, it modulates sphingosine 1-phosphate receptors to reduce immune cell migration into the central nervous system. This information was generated using AI and is provided for informational and research purposes only.
Compound 530587: 2-Chlorobenzoic acid, tridecyl ester

Chemical compound data from PubChem database. IUPAC Name: tridecyl 2-chlorobenzoate. Molecular Formula: C20H31ClO2. Molecular Weight: 338.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Weekly Cumulative RSV Vaccination Coverage, by Race and Ethnicity, Medicare Fee-For-Service Beneficiaries aged ≥75 years and enrolled in a Part D plan, United States, Data Source: Centers for Medicare & Medicaid Services Chronic Conditions Warehouse

• Weekly Cumulative RSV Vaccination Coverage, by Race and Ethnicity, Medicare Fee-For-Service Beneficiaries aged 75 years

• RSV vaccination coverage among Medicare-Fee-for-service beneficiaries aged 75 years and older and enrolled in a Part D plan in assessed using data files from the Medicare Fee-for-Service (FFS) administrative claims data managed by the Centers for Medicare & Medicaid Services (CMS).
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors

Matrix metalloproteinase (MMP)-1, MMP-8 and MMP-13 are interstitial collagenases that degrade type II collagen in cartilage; this is a committed step in the progression of rheumatoid arthritis and osteoarthritis. Of these enzymes, the expression of MMP-1 and MMP-13 is substantially increased in response to IL-1 and tumor necrosis factor-α, and elevated levels of these collagenases are observed in arthritic tissues. Therefore, cytokine-mediated MMP-1 and MMP-13 gene regulation is an important issue in arthritis research. In this review, we discuss current models of MMP-1 and MMP-13 transcriptional regulation, with a focus on signaling intermediates and transcription factors that may be future targets for the development of new arthritis drugs.
Compound 525447: 3-Methyl-2,4-dithia-6-heptene

Chemical compound data from PubChem database. IUPAC Name: 3-(1-methylsulfanylethylsulfanyl)prop-1-ene. Molecular Formula: C6H12S2. Molecular Weight: 148.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Do steroids prevent reintubation in children with laryngotracheobronchitis?

Background:
          Classic laryngotrachoebronchitis (LTB) is an inflammatory process, with oedema and secretions that involve the entire laryngotracheobronchial tree. The severity of lower airway disease in African children with LTB has previously been documented. The aim of the present study was to determine whether steroids prevent reintubation in African children with classic LTB.
        
        
          Method and results:
          The study was a retrospective analysis from January 1993 to December 1996. Eighty-two black children with LTB were mechanically ventilated in the intensive care unit (ICU). By univariate regression, the estimated B coefficients for variables such as age, pneumonia, days of intubation, arterial partial oxygen tension (PaO2) : fractional inspired oxygen (FIO2) ratio, atelectasis and antibiotic use were not statistically significant (P > 0.05) as predictors for reintubation. Using multiple regression (all independent variables in combination), none of the variables acted as predictors of reintubation (P = 0.25). Steroids were shown to have no effect alone or in association with other variables in altering reintubation rates. An increase in the days of intubation showed a tendency towards reintubation (P = 0.06) in the univariate analysis (odds ratio 1.00-1.14), but showed no statistically significant difference in multivariate analysis. Of the variables used as predictors of reintubation, none acted either as a preventive factor or as a risk factor.
        
        
          Conclusion:
          The present results suggest that steroids should not be recommended at any stage in treatment of intubated patients with classic LTB. Prospective studies should evaluate the major risk factors for reintubation: duration of intubation, trauma to the airway at intubation and during ICU stay, and dose and timing of steroids. They should also evaluate whether upper airway disease is present alone or in association with lower airway disease.
Compound 529522: 1-Bis(tert-butyldimethylsilyloxy)phosphoryl-N-(tert-butyldimethylsilyl)methanamine

Chemical compound data from PubChem database. IUPAC Name: 1-bis[[tert-butyl(dimethyl)silyl]oxy]phosphoryl-N-[tert-butyl(dimethyl)silyl]methanamine. Molecular Formula: C19H48NO3PSi3. Molecular Weight: 453.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527031: 3,6-Dimethylpyridazine

Chemical compound data from PubChem database. IUPAC Name: 3,6-dimethylpyridazine. Molecular Formula: C6H8N2. Molecular Weight: 108.14. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Neighborhood and Household Factors in the Etiology of Child Maltreatment

Two complementary research components--structured interviews with and ethnographic studies of parents--will address the two primary issues of this study. The factors being examined are (1) the ways in which neighborhood characteristics are related to parental behaviors that increase or decrease the risk of child maltreatment and (2) the ways in which parental perceptions of the neighborhood affect child maltreatment. Neighborhoods categorized as at high risk, medium risk, and low risk for child abuse and neglect reports are included in the study.

Investigators: Korbin, Jill
ARP Language Dashboard

The 210 ARP grants awarded by ANA in 2021 support the strength and vitality of an immense variety of languages spoken by Native American, Alaska Native, Native Hawaiian, and Pacific Islander communities. These grants are currently ensuring the preservation of over 120 unique languages which belong to 17 linguistic families and which encompass an even greater number of regional varieties and dialects. This dashboard provides a convenient and interactive means of exploring languages supported by these projects and acts as a springboard for learning more about the language and culture of each grant recipient.

<b>Units of Response: </b>ANA ARP Grant Recipients

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>Yes

<b>Periodicity: </b>One-time

<b>Demographic Indicators: </b>Indigenous Population

<b>SORN: </b>Not Applicable

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Not Applicable

<b>Granularity: </b>City

<b>Spatial: </b>United States

<b>Geocoding: </b>City;State
Compound 526713: 2-(2-(2-(2-(2-nonyloxy-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethanol, TFA

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-(2-nonoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl 2,2,2-trifluoroacetate. Molecular Formula: C21H39F3O7. Molecular Weight: 460.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Serological evidence of herpesvirus infection in gibbons

Background
          Herpesviruses are not only infectious agents of worldwide distribution in humans, but have also been demonstrated in various non-human primates as well. Seventy-eight gibbons were subjected to serological tests by ELISA for herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), Epstein-Barr virus (EBV) and cytomegalovirus (CMV).
        
        
          Results
          The prevalence of IgG antibodies against HSV-1, HSV-2, EBV and CMV was 28.2%, 28.2%, 14.1% and 17.9%, respectively.
        
        
          Conclusions
          Antigenic cross-reactivity is expected to exist between the human herpesviruses and gibbon herpesviruses. Gibbons have antibodies to human herpesviruses that may reflect zoonotic infection with human herpesviruses or infection with indigenous gibbon herpesviruses. Therefore, it is difficult to draw concrete conclusions from serological studies alone. Identification should be based on further isolation and molecular characterization of viruses from seropositive animals.
Patent AT-E399648-T1: [Translated] IMAGE RECORDING DEVICE

An image recording apparatus includes: a first guide member having a first sliding surface; a second guide member having another first sliding surface; and a carriage being supported by the first sliding surfaces of the first and second guide members. The carriage includes first sliding convex parts protruding from a lower surface side thereof and coming in contact with the first sliding surfaces of the first and second guide members, and a coming-out preventing pawl disposed to hold at least one of the first and second guide members in cooperation with the first sliding convex part. At least one of the first and second guide members includes a notch part at a specified position, and the carriage is detachable from the first and second guide members by causing the coming-out preventing pawl to pass through the notch part. <IMAGE>
Patent AT-E400496-T1: [Translated] UNDERWATER EXHAUST DEVICE

The device has an exhaust case (5) connected to a gas exhaust system via an exhaust pipe (4). The case is placed at the level of an exhaust outlet (7) that is situated on a hull of a ship and placed below water-line. The case is partially closed by a deflector (6) having width equal to two-third of the width of the outlet, and providing smooth profile to the hull.
Compound 5: 3-Amino-2-oxopropyl phosphate

Chemical compound data from PubChem database. IUPAC Name: (3-amino-2-oxopropyl) dihydrogen phosphate. Molecular Formula: C3H8NO5P. Molecular Weight: 169.07. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.