AndreaBozzo/ceres-open-data-index huggingface dataset:
Medicinal and ethnoveterinary remedies of hunters in Trinidad

Background
          Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success.
        
        
          Results
          Plants used include Piper hispidum, Pithecelobium unguis-cati, Bauhinia excisa, Bauhinia cumanensis, Cecropia peltata, Aframomum melegueta, Aristolochia rugosa, Aristolochia trilobata, Jatropha curcas, Jatropha gossypifolia, Nicotiana tabacum, Vernonia scorpioides, Petiveria alliacea, Renealmia alpinia, Justicia secunda, Phyllanthus urinaria,Phyllanthus niruri,Momordica charantia, Xiphidium caeruleum, Ottonia ovata, Lepianthes peltata, Capsicum frutescens, Costus scaber, Dendropanax arboreus, Siparuma guianensis, Syngonium podophyllum, Monstera dubia, Solanum species, Eclipta prostrata, Spiranthes acaulis, Croton gossypifolius, Barleria lupulina, Cola nitida, Acrocomia ierensis (tentative ID).
        
        
          Conclusion
          Plant use is based on odour, and plant morphological characteristics and is embedded in a complex cultural context based on indigenous Amerindian beliefs. It is suggested that the medicinal plants exerted a physiological action on the hunter or his dog. Some of the plants mentioned contain chemicals that may explain the ethnomedicinal and ethnoveterinary use. For instance some of the plants influence the immune system or are effective against internal and external parasites. Plant baths may contribute to the health and well being of the hunting dogs.
Bacterial cholangitis causing secondary sclerosing cholangitis: A case report

Background
          Although bacterial cholangitis is frequently mentioned as a cause of secondary sclerosing cholangitis, it appears to be extremely rare, with only one documented case ever reported.
        
        
          Case presentation
          A 48-year-old woman presented with an episode of acute biliary pancreatitis that was complicated by pancreatic abcess formation. After 3 months she had an episode of severe pyogenic (E. Coli) cholangitis that recurred over the subsequent 7 months on a further two occasions. Initially, cholangiography suggested the presence of extra-biliary intrahepatic abcesses while repeated investigations demonstrated development of multiple segmental biliary duct strictures. After maintenance antibiotic treatment was started, no episodes of cholangitis occurred over a 14-month period.
        
        
          Conclusions
          Sclerosing cholangitis can rapidly develop after an episode of bacterial cholangitis. Extra-biliary involvement of the hepatic parenchyma with abcess formation may be a risk factor for developing this rare but particularly severe complication.
Compound 530026: 5-Fluoro-2-nitrophenyl 2-methoxybenzoate

Chemical compound data from PubChem database. IUPAC Name: 2-methoxy-3-trimethylsilyloxybenzaldehyde. Molecular Formula: C11H16O3Si. Molecular Weight: 224.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
FcgammaR expression on macrophages is related to severity and chronicity of synovial inflammation and cartilage destruction during experimental immune-complex-mediated arthritis (ICA)

We investigated the role of Fcγ receptors (FcγRs) on synovial macrophages in immune-complex-mediated arthritis (ICA). ICA elicited in knee joints of C57BL/6 mice caused a short-lasting, florid inflammation and reversible loss of proteoglycans (PGs), moderate chondrocyte death, and minor erosion of the cartilage. In contrast, when ICA was induced in knee joints of Fc receptor (FcR) γ-chain-/- C57BL/6 mice, which lack functional FcγRI and RIII, inflammation and cartilage destruction were prevented. When ICA was elicited in DBA/1 mice, a very severe, chronic inflammation was observed, and significantly more chondrocyte death and cartilage erosion than in arthritic C57BL/6 mice. The synovial lining and peritoneal macrophages of naïve DBA/1 mice expressed a significantly higher level of FcγRs than was seen in C57BL/6 mice. Moreover, elevated and prolonged expression of IL-1 was found after stimulation of these cells with immune complexes. Zymosan or streptococcal cell walls caused comparable inflammation and only mild cartilage destruction in all strains. We conclude that FcγR expression on synovial macrophages may be related to the severity of synovial inflammation and cartilage destruction during ICA.
Compound 529154: n-Heptyl(trimethyl)silanamine

Chemical compound data from PubChem database. IUPAC Name: N-trimethylsilylheptan-1-amine. Molecular Formula: C10H25NSi. Molecular Weight: 187.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530668: 4-Butylbenzoic acid, 2,6-dimethylnon-1-en-3-yn-5-yl ester

Chemical compound data from PubChem database. IUPAC Name: 2,6-dimethylnon-1-en-3-yn-5-yl 4-butylbenzoate. Molecular Formula: C22H30O2. Molecular Weight: 326.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Wyoming (WY)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Wyoming for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Patent AT-E400696-T1: [Translated] FRAME THRESHOLD FOR A RAILWAY BALARLAD SURFACE AND METHOD FOR THE PRODUCTION THEREOF

The invention relates to a sleeper frame for a ballasted railway track, comprising two transverse sleepers (1) and two longitudinal supports, running under the tracks, whereby each longitudinal support unit comprises at least two diagonal bars (2) arranged in a truss-like manner, lying one over the other in at least two horizontal planes, crossing in the middle between the transverse sleepers (1) and arranged symmetrically about the rail axis. Bar elements (3) are provided as diagonal bars (2) in the form of reinforcement rods or steel bar profiles, anchored in tubular openings (4) in the transverse sleepers (1) with injection mortar (6). The invention further relates to a production method, whereby firstly transverse sleepers (1) of any type are produced in conventional production equipment, then provided with rod elements (3) and further components on an assembly platform (8) and the assembly platform (8) is then tipped through at least 45 DEG and the rod elements (3) pressed in in this position.
Blood substitutes

Blood substitutes have long been sought after, and artificial oxygen		  carriers may soon become a reality. Despite increased safety of allogeneic		  blood in terms of transmission of infectious diseases [1], avoiding allogeneic blood transfusions remains an important		  goal in perioperative and intensive care medicine. This is because allogeneic		  blood transfusions may cause immunosuppression with an increased incidence of		  postoperative infections [2,3] and		  may adversely affect outcome in intensive care [4], and		  thus they remain a public concern [5].
Idaho: 2011-2012 NSDUH

This report presents Idaho\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 527296: 2-((4-[(7-Chloro-4-quinolinyl)amino]benzyl)amino)ethanol

Chemical compound data from PubChem database. IUPAC Name: 4-butyl-1,2-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527198: 5,6-Dimethyl-8-prop-1-en-2-yl-11-oxatricyclo[6.2.1.01,6]undec-2-ene

Chemical compound data from PubChem database. IUPAC Name: 5,6-dimethyl-8-prop-1-en-2-yl-11-oxatricyclo[6.2.1.01,6]undec-2-ene. Molecular Formula: C15H22O. Molecular Weight: 218.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The minisequencing method: a simple strategy for genetic screening of MEN 2 families

Background
          Multiple endocrine neoplasia type 2 is an autosomal dominant disorder. MEN 2A is characterized by medullary thyroid carcinoma, pheochromocytoma and hyperparathyroidism; MEN 2B by medullary thyroid carcinoma, pheochromocytoma and characteristic stigmata. Activating germline mutations of the RET proto oncogene are responsible for this hereditary syndrome. Codon 634 mutations are the most common mutations occurring in MEN 2A families whereas a specific mutation at codon 918 is observed in the great majority of MEN 2B families. Analysis of these codons will provide a final diagnosis in the great majority of affected families making unnecessary further studies. To specifically study the codons 634 and 918 we used a minisequencing method as an alternative method to complete sequencing.
        
        
          Results
          Using this mutation detection method we were able to reproduce in all cases, representative of 7 families, the information previously obtained by direct sequencing of PCR products. Depending on the number of primers used in the minisequencing reaction, we were able to interrogate either only one nucleotide of the target codon or the three nucleotides simultaneously.
        
        
          Conclusions
          This technique appears as a simple, rapid and efficient method for genetic screening of MEN 2 families. It can be utilized to seek for unknown mutations at specific codons or to screen for previously identified mutations and is therefore of interest to study index cases or individuals at risk. Results suggest that complete sequencing is unnecessary.
Compound 527528: 1-Butyl-2,5-dimethyl-1H-pyrrole

Chemical compound data from PubChem database. IUPAC Name: 1-butyl-2,5-dimethylpyrrole. Molecular Formula: C10H17N. Molecular Weight: 151.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Inpatient Sample (NIS) - Restricted Access Files

The Healthcare Cost and Utilization Project (HCUP) National Inpatient Sample (NIS) is the largest publicly available all-payer inpatient care database in the United States. The NIS is designed to produce U.S. regional and national estimates of inpatient utilization, access, cost, quality, and outcomes. Unweighted, it contains data from more than 7 million hospital stays each year. Weighted, it estimates more than 35 million hospitalizations nationally. Developed through a Federal-State-Industry partnership sponsored by the Agency for Healthcare Research and Quality (AHRQ), HCUP data inform decision making at the national, State, and community levels.

Starting with the 2012 data year, the NIS is a sample of discharges from all hospitals participating in HCUP, covering more than 97 percent of the U.S. population. For prior years, the NIS was a sample of hospitals. The NIS allows for weighted national estimates to identify, track, and analyze national trends in health care utilization, access, charges, quality, and outcomes. The NIS's large sample size enables analyses of rare conditions, such as congenital anomalies; uncommon treatments, such as organ transplantation; and special patient populations, such as the uninsured. NIS data are available since 1988, allowing analysis of trends over time. 

The NIS inpatient data include clinical and resource use information typically available from discharge abstracts with safeguards to protect the privacy of individual patients, physicians, and hospitals (as required by data sources).  Data elements include but are not limited to: diagnoses, procedures, discharge status, patient demographics (e.g., sex, age), total charges, length of stay, and expected payment source, including but not limited to Medicare, Medicaid, private insurance, self-pay, or those billed as ‘no charge’. The NIS excludes data elements that could directly or indirectly identify individuals. 

Restricted access data files are available with a data use agreement and brief online security training.
Compound 526040: Silane, [[(17beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diyl]bis(oxy)]bis*trimethyl-

Chemical compound data from PubChem database. IUPAC Name: (2-methoxy-13-methyl-3-trimethylsilyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)oxy-trimethylsilane. Molecular Formula: C25H42O3Si2. Molecular Weight: 446.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526631: [4-Acetyloxy-5-(methoxymethyl)oxolan-3-yl] acetate

Chemical compound data from PubChem database. IUPAC Name: [4-acetyloxy-5-(methoxymethyl)oxolan-3-yl] acetate. Molecular Formula: C10H16O6. Molecular Weight: 232.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525351: 2,2-Dimethyl-3,5-dithiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-(ethylsulfanylmethylsulfanyl)-2-methylpropane. Molecular Formula: C7H16S2. Molecular Weight: 164.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Suicidal Thoughts among Asians, Native Hawaiians, or Other Pacific Islanders (2008 to 2011 NSDUH)

This report uses 2008 to 2011 National Survey on Drug Use and Health (NSDUH) to assess past year serious thoughts of suicide, suicide plans, or suicide attempts among Asians, Native Hawaiians, or Other Pacific Islanders adults aged 18 or older. Comparisons are made to the National Average.
16th NCCAN Commissioner's Award Book

The ACYF 2007 Commissioner's Awards book provides descriptions and photographs of the honorees from 38 states, the District of Columbia, and 5 territories who were recognized for their exceptional contributions to the prevention and treatment of child abuse and neglect. The ACYF Commissioner's Awards are presented every 2 years in association with NCCAN. Nominations are made by the governors of states and territories.

Metadata-only record linking to the original dataset. Open original dataset below.
Genomic structure of the gene for mouse germ-cell nuclear factor (GCNF). II. Comparison with the genomic structure of the human

Background:
          Germ-cell nuclear factor (GCNF, NR6AI) is an orphan nuclear receptor. Its expression pattern suggests it functions during embryogenesis, in the placenta and in germ-cell development. Mouse GCNF cDNA codes for a protein of 495 amino acids, whereas the four reported human cDNA variants code for proteins of 454 to 480 amino acids. Apart from this size difference, there is sequence conservation of up to 98.7%. To elucidate the genomic structure that gives rise to the different human GCNF mRNAs, the sequence information of the human GCNF locus is compared to the previously reported structure of the mouse locus.
        
        
          Results:
          The genomic structures of the mouse and human GCNF genes are highly conserved. The comparison reveals that the shorter human protein results from skipping the 45 base-pair third exon. Three different human isoforms - GCNF-1, GCNF-2a and GCNF-2b - are generated by differential usage of alternative splice acceptor sites of the fourth and the seventh exon.
        
        
          Conclusion:
          By homology with the mouse gene, 11 GCNF coding exons can be defined on human chromosome 9. All human GCNF cDNAs identified so far are, however, derived from mRNAs generated by splicing the fourth to the second exon. Although the genomic sequence is highly conserved, the analysis suggests that alternative splicing generates a higher complexity of human GCNF isoforms compared with the situation in the mouse.
NCHS Survey Data Linked to Centers for Medicare & Medicaid Services (CMS) Medicare Data Files

NCHS has linked data from various surveys with Medicare program enrollment and health care utilization and expenditure data from the Centers for Medicare & Medicaid Services (CMS). Linkage of the NCHS survey participants with the CMS Medicare data provides the opportunity to study changes in health status, health care utilization and costs, and prescription drug use among Medicare enrollees. Medicare is the federal health insurance program for people who are 65 or older, certain younger people with disabilities, and people with End-Stage Renal Disease.
Patent AT-E400982-T1: [Translated] IMPROVED ELECTRICAL CONNECTOR

An electrical connector (10) for connecting an electrically heated vehicle windowpane to an external power source is disclosed. Electrical connector (10) comprises at least two strips (12) of conducting material, arranged substantially adjacent each other in a mutually spaced relationship, each of which is provided with a separate sleeve (13) of insulating material. Electrical connector (10) includes means for maintaining insulated strips (16) in a spaced relationship; preferably said means is bridging member (17). Preferably each insulated strip (16) a) includes un-insulated region (14) at one end to enable electrical connection to the vehicle windowpane to be made, and b) has a connection to power source connection cable (18) established at the other end; the established connection being housed within connection block (11).
Chromosomal mapping, gene structure and characterization of the human and murine

Background
          Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in Griscelli Disease, a disease combining partial albinism with severe immunodeficiency. Rab27a plays a key role in the function of lysosomal-like organelles such as melanosomes in melanocytes and lytic granules in cytotoxic T lymphocytes. Little is known about Rab27b.
        
        
          Results
          The human RAB27B gene is organised in six exons, spanning about 69 kb in the chromosome 18q21.1 region. Exon 1 is non-coding and is separated from the others by 49 kb of DNA and exon 6 contains a long 3' untranslated sequence (6.4 kb). The mouse Rab27b cDNA shows 95% identity with the human cDNA at the protein level and maps to mouse chromosome 18. The mouse mRNA was detected in stomach, large intestine, spleen and eye by RT-PCR, and in heart, brain, spleen and kidney by Northern blot. Transient over-expression of EGF-Rab27b fusion protein in cultured melanocytes revealed that Rab27b is associated with melanosomes, as observed for EGF-Rab27a.
        
        
          Conclusions
          Our results indicate that the Rab27 subfamily of Ras-like GTPases is highly conserved in mammals. There is high degree of conservation in sequence and gene structure between RAB27A and RAB27B genes. Exogenous expression of Rab27b in melanocytes results in melanosomal association as observed for Rab27a, suggesting the two Rab27 proteins are functional homologues. As with RAB27A in Griscelli Disease, RAB27B may be also associated with human disease mapping to chromosome 18.
Information Memorandum (IM-18-04)

This Information Memorandum (IM) notifies states that the Children’s Bureau is disbursing funding provided under section 437(g) of the Act as an increase in the title IV-B subpart 2 Promoting Safe and Stable Families Program allocation to support an electronic interstate case-processing system to expedite interstate placements of children in foster, guardianship or adoptive homes, and to provide an example of such an electronic interstate system.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 526861: Pentaethylene glycol, pentyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-(2-pentoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl acetate. Molecular Formula: C17H34O7. Molecular Weight: 350.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528671: Succinylaceton, oxime, mono-TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 4,6-bis(hydroxyimino)heptanoate. Molecular Formula: C10H20N2O4Si. Molecular Weight: 260.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
COVID-19 State Profile Report - Idaho

<b>After over two years of public reporting, the State Profile Report will no longer be produced and distributed after February 2023. The final release was on February 23, 2023. We want to thank everyone who contributed to the design, production, and review of this report and we hope that it provided insight into the data trends throughout the COVID-19 pandemic.
Data about COVID-19 will continue to be updated at <a href='https://covid.cdc.gov/covid-data-tracker/#datatracker-home' >CDC’s COVID Data Tracker</a>.
 </b>

<p>
The State Profile Report (SPR) is generated by the Data Strategy and Execution Workgroup in the Joint Coordination Cell, in collaboration with the White House. It is managed by an interagency team with representatives from multiple agencies and offices (including the United States Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention, the HHS Assistant Secretary for Preparedness and Response, and the Indian Health Service). The SPR provides easily interpretable information on key indicators for each state, down to the county level.
 </p>

It is a weekly snapshot in time that:
<ul>
<li>Focuses on recent outcomes in the last seven days and changes relative to the month prior</li>
<li>Provides additional contextual information at the county level for each state, and includes national level information</li>
<li>Supports rapid visual interpretation of results with color thresholds</li>
</ul>