AndreaBozzo/ceres-open-data-index huggingface dataset:
Biochemical, electron microscopic and immunohistological observations of cationic detergent-extracted cells: detection and improved preservation of microextensions and ultramicroextensions

Background
          Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen preparation for microscopy. To preserve these structures for electron microscopy glutaraldehyde is generally used, but it often causes antigen masking. By contrast, formaldehyde is generally used for immunofluorescence light microscopy, but few studies have been concerned with the loss of microextensions.
        
        
          Results
          We demonstrate in biochemical experiments that cultured cells needed to be kept in 4% formaldehyde for at least 60 min at room temperature or for 20 min at 37°C to irreversibly crosslink most of the polypeptides. Also, fragmentation of fragile microextensions was observed after Triton X-100 extraction depending on concentration and extent of crosslinking. We also report on a novel fixation procedure that includes the cationic detergent dodecyltrimethylammonium chloride (DOTMAC). Treatment of NIH3T3 cells with DOTMAC resulted in complete removal of membrane lipids and in good preservation of the cytoskeleton in microextensions as well as preservation of ultramicroextensions of <0.05μm in diameter that have not been observed previously unless glutaraldehyde was used. Stress fibers and microextensions of DOTMAC-extracted cells were readily stained with anti-β-actin antibodies, and antibodies to vinculin and moesin stained focal contacts and microextensions, respectively.
        
        
          Conclusions
          Some microextensions were fragmented by the standard Triton X-100 permeabilization method. By contrast, DOTMAC completely extracted membrane lipids while maintaining the cytoskeleton of microextensions. Thus, DOTMAC treatment may provide a valuable new tool for the reliable visualization of previously undetectable or poorly detectable antigens while preserving the actin cytoskeleton of microextensions.
Compound 528678: 1-Methyl-3-n-Pentylbenzene

Chemical compound data from PubChem database. IUPAC Name: 1-methyl-3-pentylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Population-Weighted Global Horizontal Irradiance, 1991-2012

This dataset provides data at the county level for the contiguous United States. It includes daily Global Horizontal Irradiance (GHI) data from 1991-2012 provided by the Environmental Remote Sensing group at the Rollins School of Public Health at Emory University. Please refer to the metadata attachment for more information.

These data are used by the CDC's National Environmental Public Health Tracking Network to generate sunlight and ultraviolet (UV) measures. Learn more about sunlight and UV on the Tracking Network's website: https://ephtracking.cdc.gov/showUVLanding.

By using these data, you signify your agreement to comply with the following requirements: 
1.	Use the data for statistical reporting and analysis only. 
2.	Do not attempt to learn the identity of any person included in the data and do not combine these data with other data for the purpose of matching records to identify individuals. 
3.	Do not disclose of or make use of the identity of any person or establishment discovered inadvertently and report the discovery to: trackingsupport@cdc.gov. 
4.	Do not imply or state, either in written or oral form, that interpretations based on the data are those of the original data sources and CDC unless the data user and data source are formally collaborating. 
5.	Acknowledge, in all reports or presentations based on these data, the original source of the data and CDC. 
6.	Suggested citation: Centers for Disease Control and Prevention. National Environmental Public Health Tracking Network. Web. Accessed: insert date. www.cdc.gov/ephtracking. 

Problems or Questions? 
Email trackingsupport@cdc.gov.
Compound 527422: (1,7,7-Trimethyl-2-bicyclo[2.2.1]heptanyl) 2-methylbut-2-enoate

Chemical compound data from PubChem database. IUPAC Name: (1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl) 2-methylbut-2-enoate. Molecular Formula: C15H24O2. Molecular Weight: 236.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Dicyclomine hydrochloride

Dicyclomine Hydrochloride is a prescription medication available as an injectable solution for intramuscular use. Each milliliter contains 10 mg of the active ingredient, which works as an anticholinergic to help relieve muscle spasms in the digestive tract. It's supplied in 2 mL single-dose vials, packaged in cartons of 5. Manufactured by Fosun Pharma USA Inc., this generic drug is approved under ANDA 210979. This information was generated using AI and is provided for informational and research purposes only.
Evidence-Based Practices Resource Center

<p>The Evidence-Based Practices Resource Center aims to provide communities, clinicians, policy-makers and others in the field with the information and tools they need to incorporate evidence-based practices into their communities or clinical settings. The Resource Center contains a collection of scientifically-based resources for a broad range of audiences, including Treatment Improvement Protocols, toolkits, resource guides, clinical practice guidelines, and other science-based resources.</p>
Compound 528007: 2-Propynyl 3,5-dinitrobenzoate

Chemical compound data from PubChem database. IUPAC Name: prop-2-ynyl 3,5-dinitrobenzoate. Molecular Formula: C10H6N2O6. Molecular Weight: 250.16. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525135: Butyl n-heptyl phthalate

Chemical compound data from PubChem database. IUPAC Name: 1-O-butyl 2-O-heptyl benzene-1,2-dicarboxylate. Molecular Formula: C19H28O4. Molecular Weight: 320.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The Metal Coordination of sCD39 during ATP Hydrolysis

Background
          The hydrolysis of ATP and ADP by ecto-nucleoside triphosphate diphosphohydrolase 1 (CD39) requires divalent cations, like Ca2+ and Mg2+. In spite of considerable work, it is not clear whether divalent cations bind to the enzyme in the absence of nucleotide or only as nucleotide-Me+2 complex. Here we study the protein ligands for Me+2.
        
        
          Results
          When VO2+ was used as a substitute for Ca2+, the ATPase activity of soluble CD39 was 25% of that with Ca2+ as cofactor. Protein ligands of the VO2+-nucleotide complex bound to the catalytic site of soluble CD39 were characterized by electron paramagnetic resonance (EPR) spectroscopy. The EPR spectrum contained one species designated T with VO2+-AMPPNP as ligand. Two species D1 and D2 were observed when VO2+-AMPCP was bound to soluble CD39. The results suggest that species D1 and D2 represent the metal-ADP complexes at the catalytic site of soluble CD39 corresponding to the intermediate formed during ATP hydrolysis and the substrate for further hydrolysis, respectively.
        
        
          Conclusions
          VO2+ can functionally substitute for Ca2+ as a cofactor of sCD39, and it produces four different EPR features when bound in the presence of different nucleotides or in the absence of nucleotide. The metal coordination for each conformation corresponding to each EPR species is proposed, and the mechanism of sCD39 catalysis is discussed.
Compound 527439: 3-Mercapto-2-methylbutanal

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-3-sulfanylbutanal. Molecular Formula: C5H10OS. Molecular Weight: 118.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527194: 2,6-Dimethyl-8-prop-1-en-2-yl-7-oxatricyclo[6.2.1.01,6]undec-4-ene

Chemical compound data from PubChem database. IUPAC Name: 2,6-dimethyl-8-prop-1-en-2-yl-7-oxatricyclo[6.2.1.01,6]undec-4-ene. Molecular Formula: C15H22O. Molecular Weight: 218.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400739-T1: [Translated] SADDLE BEARING BUSH FOR AN AXIAL PISTON PUMP

A saddle bearing liner ( 30 ) for a variable displacement axial piston pump ( 10 ) includes two axially-spaced apart bearing surfaces ( 62, 64 ) with an offset central section ( 54 ) integrally joining them. A hollow projection ( 80 ) extends radially from the convex side of the pressure bearing section ( 50 ) and is received with a recess ( 82 ) of the housing ( 12 ) to locate the liner ( 30 ). The liner ( 30 ) has radially extending ledges ( 70, 72 ) which mate with surfaces ( 74, 76 ) of the housing ( 12 ) to inhibit skewing of the bearing liner ( 30 ) relative to the axis of the bearing surfaces ( 62, 64 ). The projection ( 80 ) is hollow and opens to the bearing surface ( 62 ) so that presurrized fluid from the housing ( 12 ) can be injected between the bearing surface ( 62 ) and the mating surface ( 22 ) of the swashblock ( 20 ). The projection ( 80 ) also prevents the liner ( 30 ) from rotating about the bearing surface axis.
Compound 530485: 5-Chlorovaleric acid, heptadecyl ester

Chemical compound data from PubChem database. IUPAC Name: heptadecyl 5-chloropentanoate. Molecular Formula: C22H43ClO2. Molecular Weight: 375.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
HCUP Fast Stats

Healthcare Cost and Utilization Project (HCUP) Fast Stats provides easy access to the latest HCUP-based statistics for health care information topics. HCUP Fast Stats uses visual statistical displays in stand-alone graphs, trend figures, or simple tables
to convey complex information at a glance. Fast Stats is updated regularly for timely, topic-specific national and State-level statistics.

Fast Stats topics and graphics on hospital stays and emergency department visits, including information at the national, and state levels, trends over time, and selected priority topics such as:
<li>State Trends in Hospital User by Payer
<li>National Hospital Utilization and Costs
<li>Hurricane Impact on Hospital Use
<li>Opioids & Neonatal Abstinence Syndrome
<li>Severe Maternal Morbidity
2010 State Profile — California

This state profile includes data from facilities in California that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in California. In California, 1,626 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 123,611 clients in substance abuse treatment on March 31, 2010. The survey response rate in California was 89.5%.
QHP Landscape PY2023 Dental SHOP

The Dental SHOP Market file of the QHP Landscape Files contains information on certified dental plans offered through an Exchange to employers in the Small Business Health Options Program (SHOP) market. These plans are also known as Stand-alone Dental Plans (SADPs). The file reports plans offered by county for states in the Federally-facilitated Exchanges including states performing plan management functions, and State Based Exchanges using the federal platform for eligibility and enrollment.
Patent AT-E39980-T1: [Translated] DRIVE BELT.

A power transmission belt wherein at least a portion thereof is formed as a composite of 1 to 100 parts by weight of whiskers (25) distributed in 100 parts by weight of rubber. The composite may form the compression section of the belt. The composite may be utilized as impregnating rubber for a fabric cover portion of the belt. The whiskers preferably have a diameter in the range of approximate 0.1 micron to 1.0 micron, and a length of approximately 10 microns to 500 microns. In the illustrated embodiment, the whiskers are acicular single crystal whiskers.
Compound 529809: 2-Propenal, 2-methyl, 2,4,6-trichlorophenyl hydrazone

Chemical compound data from PubChem database. IUPAC Name: 2,4,6-trichloro-N-(2-methylprop-2-enylideneamino)aniline. Molecular Formula: C10H9Cl3N2. Molecular Weight: 263.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
New Hampshire 2016 Potential Areas for Addressing Service Gaps for Opioid Treatment

The purpose of the medication-assisted treatment (MAT) facility maps is to identify areas on a state-by-state basis that may be potentially underserved by existing treatment facilities. The maps are created with a methodology that seeks to include the highest potential need areas from individual counties so that county-level stakeholders are also informed. The maps are meant to be used as a tool for policy makers to determine potentially underserved areas—not as a definitive representation of these areas.
Total Inward Leakage (TIL) for Respiratory Protective Devices

Total inward leakage (TIL) is an estimate of the performance of a respirator, which is measured as the leakage of contaminants through the filter media and through the faceseal interface and exhalation valve of respiratory protective devices under laboratory conditions. Several test agents have been used to measure TIL in different countries. There is a lack of consensus on the most appropriate test method to measure TIL. The International Organization for Standardization (ISO) developed a standard (ISO, 2014) on the comparison of TIL measurement using sodium chloride (NaCl) and corn oil aerosols, and sulfur hexafluoride gas. A comparison of the TIL values between different methods will enable the selection of a relatively suitable method for measuring TIL. NIOSH’s National Personal Protective Technology Laboratory (NPPTL) investigated the TIL values for respirators worn by test subjects exposed to NaCl and corn oil aerosols in two aerosol chambers side-by-side. Four air-purifying respirator categories, made
Efficacy of powered air-purifying respirators (PAPRs) for source control of simulated respiratory aerosols-dataset

Powered air purifying respirators (PAPRs) are a popular alternative to the use of filtering facepiece respirators by healthcare workers. Although PAPRs protect the wearer from aerosol particles, their ability to block infectious aerosol particles exhaled by the wearer from being released into the environment (called source control) is unclear.
Compound 529140: 1-Decanamine, mono-DMTBS

Chemical compound data from PubChem database. IUPAC Name: N-[tert-butyl(dimethyl)silyl]decan-1-amine. Molecular Formula: C16H37NSi. Molecular Weight: 271.56. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table II. Spotted fever rickettsiosis to Syphilis, primary and secondary

NNDSS - Table II. Spotted fever rickettsiosis to Syphilis, primary and secondary - 2018. In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed. The Table includes total number of cases reported in the United States, by region and by states or territory.

Note:

This table contains provisional cases of selected national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up.  Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html.
 
Footnotes:

C.N.M.I.: Commonwealth of Northern Mariana Islands. 
U: Unavailable. —: No reported cases. N: Not reportable. NA:  Not Available.  NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum.
 
* Case counts for reporting years 2017 and 2018 are provisional and subject to change. Data for years 2013 through 2016 are finalized. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf.
Patent AT-E400905-T1: [Translated] CERAMIC FUEL CELL

A honeycomb ceramic fuel cell is provided including, among other things, (i) an yttria stabilized bismuth oxide oxygen ion conductive ceramic with zirconia incorporated therein, (ii) a niobia stabilized bismuth oxide oxygen ion conductive ceramic, (iii) a copper cermet anode electrode disposed in the fuel supply passage of a bismuth oxide ceramic fuel cell, or (iv) specially arranged inter-passage channels formed in the ceramic body of the fuel cell. In accordance with one embodiment of the present invention, a ceramic fuel cell is provided comprising an oxidant supply passage, a cathode electrode disposed in the oxidant supply passage, a fuel supply passage, an anode electrode disposed in the fuel supply passage, and a stabilized bismuth oxide oxygen ion conductive ceramic interposed between the cathode electrode and the anode electrode. The ceramic may be stabilized with yttria or niobia and may include zirconia. Fuel cells incorporating the ceramic compositions of the present invention are operational at temperatures at or below about 650° C. Thus, sooting of the ceramic body is not a problem if unreformed organic fuels are utilized in the present invention. According to certain embodiments of the present invention, a zirconia coating is interposed between the stabilized ceramic body and the anode electrode. Further, the ceramic electrodes of the present invention may be provided with a silver overlay.
Compound 526963: bis-(3-Nitrophenyl)acetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2,2-bis(3-nitrophenyl)acetate. Molecular Formula: C15H12N2O6. Molecular Weight: 316.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2013 CMHS Uniform Reporting System (URS) Tables for Hawaii

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Hawaii for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Hepatitis B virus infected physicians and disclosure of transmission risks to patients: A critical analysis

Background
          The potential for transmission of blood-borne pathogens such as hepatitis B virus from infected healthcare workers to patients is an important and difficult issue facing healthcare policymakers internationally. Law and policy on the subject is still in its infancy, and subject to a great degree of uncertainty and controversy. Policymakers have made few recommendations regarding the specifics of practice restriction for health care workers who are hepatitis B seropositive. Generally, they have deferred this work to vaguely defined "expert panels" which will have the power to dictate the conditions under which infected health care workers may continue to practice.
        
        
          Discussion
          In this paper we use recent Canadian policy statements as a critical departure point to propose more specific recommendations regarding disclosure of transmission risks in a way that minimizes practice restriction of hepatitis B seropositive health care workers without compromising patient safety. The range of arguments proposed in the literature are critically examined from the perspective of ethical analysis.
        
        
          Summary
          A process for considering the ethical implications of the disclosure of the sero-status of health care workers is advanced that considers the varied perspectives of different stakeholders.
Montana 2016 Potential Areas for Addressing Service Gaps for Opioid Treatment

The purpose of the medication-assisted treatment (MAT) facility maps is to identify areas on a state-by-state basis that may be potentially underserved by existing treatment facilities. The maps are created with a methodology that seeks to include the highest potential need areas from individual counties so that county-level stakeholders are also informed. The maps are meant to be used as a tool for policy makers to determine potentially underserved areas—not as a definitive representation of these areas.
2011 CMHS Uniform Reporting System Output Tables

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 530628: Valeric acid, but-3-yn-2-yl ester

Chemical compound data from PubChem database. IUPAC Name: but-3-yn-2-yl pentanoate. Molecular Formula: C9H14O2. Molecular Weight: 154.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400893-T1: [Translated] A COLLECTION AND FILE ASSEMBLY TO TRANSPORT A FILM

The invention provides a pick and place assembly for transferring a film of material. The assembly comprises a collet having a substantially convex contact surface for contacting the film, the collet including a vacuum suction device operative to generate a force to hold the film. The film may comprise a thermoplastic adhesive tape or B-stage thermoset epoxy coated film. <IMAGE>
Diligent Recruitment of Families for Children in the Foster Care System: Challenges and Recommendations for Policy and Practice

Diligent Recruitment of Families for Children in the Foster Care System: Challenges and Recommendations for Policy and Practice describes how child welfare agencies can improve diligent recruitment practices and services for resource families. It is based on grantee final reports and published research and presents activities undertaken by grantees, lessons learned, and suggestions for improvement.

Metadata-only record linking to the original dataset. Open original dataset below.