AndreaBozzo/ceres-open-data-index huggingface dataset:
Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions

Background
          It has recently been shown that the detection of gene fusion events across genomes can be used for predicting functional associations of proteins, including physical interaction or complex formation. To obtain such predictions we have made an exhaustive search for gene fusion events within 24 available completely sequenced genomes.
        
        
          Results
          Each genome was used as a query against the remaining 23 complete genomes to detect gene fusion events. Using an improved, fully automatic protocol, a total of 7,224 single-domain proteins that are components of gene fusions in other genomes were detected, many of which were identified for the first time. The total number of predicted pairwise functional associations is 39,730 for all genomes. Component pairs were identified by virtue of their similarity to 2,365 multidomain composite proteins. We also show for the first time that gene fusion is a complex evolutionary process with a number of contributory factors, including paralogy, genome size and phylogenetic distance. On average, 9% of genes in a given genome appear to code for single-domain, component proteins predicted to be functionally associated. These proteins are detected by an additional 4% of genes that code for fused, composite proteins.
        
        
          Conclusions
          These results provide an exhaustive set of functionally associated genes and also delineate the power of fusion analysis for the prediction of protein interactions.
TABLE III. Deaths in 122 U.S. cities

TABLE III. Deaths in 122 U.S. cities – 2016.  122 Cities Mortality Reporting System — Each week, the vital statistics offices of 122 cities across the United States report the total number of death certificates processed and the number of those for which pneumonia or influenza was listed as the underlying or contributing cause of death by age group (Under 28 days, 28 days –1 year, 1-14 years, 15-24 years, 25-44 years, 45-64 years, 65-74 years, 75-84 years, and ≥ 85 years).

FOOTNOTE:
U: Unavailable. —: No reported cases.
* Mortality data in this table are voluntarily reported from 122 cities in the United States, most of which have populations of 100,000 or more. A death is reported by the place of its occurrence and by the week that the death certificate was filed. Fetal deaths are not included. 

† Pneumonia and influenza. 

§ Total includes unknown ages.
Bone loss: Therapeutic approaches for preventing bone loss in inflammatory arthritis

Inflammatory arthritides are commonly characterized by localized and generalized bone loss. Localized bone loss in the form of joint erosions and periarticular osteopenia is a hallmark of rheumatoid arthritis, the prototype of inflammatory arthritis. Recent studies have highlighted the importance of receptor activator of nuclear factor-κB ligand (RANKL)-dependent osteoclast activation by inflammatory cells and subsequent bone loss. In this article, we review the pathogenesis of inflammatory bone loss and explore the possible therapeutic interventions to prevent it.
Compound 525716: N-(4-Methylbenzylidene)-3-nitroaniline

Chemical compound data from PubChem database. IUPAC Name: 1-(4-methylphenyl)-N-(3-nitrophenyl)methanimine. Molecular Formula: C14H12N2O2. Molecular Weight: 240.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The International Sepsis Forum's controversies in sepsis: corticosteroids should not be routinely used to treat septic shock

Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been evaluated in scores of studies spanning 3–4 decades. Yet, convincing proof that corticosteroids are useful pharmacologic agents in the treatment of this major clinical problem remains elusive. Recently, interest has resurfaced but this time the focus is on a steroid replacement approach for what has now been termed "relative adrenal insufficiency" rather than relying on the pharmacologic effects of steroids. This route holds promise, but proof remains lacking.
Compound 526228: 1,2,3,6,8-Pentabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,3,6,8-pentabromodibenzofuran. Molecular Formula: C12H3Br5O. Molecular Weight: 562.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NSDUH 2021 Sample Experience Report

This report is a continuation of the 2021National Survey on Drug Use and Health (NSDUH) Sample Design Report. It further documents the 2021 NSDUH sample experiences, by comparing expected outcomes with what actually occurred, and documenting unexpected issues that came up during the year. The report also summarizes the information about the sample design that is more thoroughly detailed in the previous report.Chapter 1 introduces the report and summarizes the impact of the coronavirus 2019 pandemic on the sample design and data collection. Chapter 2 revisits the 2021 sample design. Chapters 3, 4, and 5 document the sample experiences at the third, fourth, and fifth stages of sample selection, respectively. Finally, Chapter 6 compares the observed and expected precisions, and also examines trends in average design effects over time.The document is available as a PDF.
COVID-19 State Profile Report - Washington

<b>After over two years of public reporting, the State Profile Report will no longer be produced and distributed after February 2023. The final release was on February 23, 2023. We want to thank everyone who contributed to the design, production, and review of this report and we hope that it provided insight into the data trends throughout the COVID-19 pandemic.
Data about COVID-19 will continue to be updated at <a href='https://covid.cdc.gov/covid-data-tracker/#datatracker-home' >CDC’s COVID Data Tracker</a>.
 </b>

<p>
The State Profile Report (SPR) is generated by the Data Strategy and Execution Workgroup in the Joint Coordination Cell, in collaboration with the White House. It is managed by an interagency team with representatives from multiple agencies and offices (including the United States Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention, the HHS Assistant Secretary for Preparedness and Response, and the Indian Health Service). The SPR provides easily interpretable information on key indicators for each state, down to the county level.
 </p>

It is a weekly snapshot in time that:
<ul>
<li>Focuses on recent outcomes in the last seven days and changes relative to the month prior</li>
<li>Provides additional contextual information at the county level for each state, and includes national level information</li>
<li>Supports rapid visual interpretation of results with color thresholds</li>
</ul>
Behavioral Health Barometer: Texas, 2014

This is a behavioral health report for the state of Texas. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment, and medicare enrollees for the years 2009 to 2013.
Nalmefene hydrochloride injection

Nalmefene Hydrochloride Injection is a prescription opioid antagonist used to reverse opioid overdoses. It comes in solution form for intramuscular, intravenous, or subcutaneous administration, with strengths like 0.1 mg/mL or 1 mg/mL. Manufactured by Chengdu Shuode Pharmaceutical Co., Ltd. This information was generated using AI and is provided for informational and research purposes only.
Compound 528255: Thiophene, 4-methyl-2-propyl

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-2-propylthiophene. Molecular Formula: C8H12S. Molecular Weight: 140.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2012 Uniform Reporting System (URS) Tables for Nebraska

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Chlorhexidine gluconate and isopropyl alcohol

3M SoluPrep S is an over-the-counter topical antiseptic solution containing 2% chlorhexidine gluconate and 70% isopropyl alcohol. It's used to clean and disinfect the skin before medical procedures, helping to reduce bacteria and prevent infections. Available in applicator pouches (26 mL or 10.5 mL), apply to the skin as directed. Manufactured by Solventum US LLC. This information was generated using AI and is provided for informational and research purposes only.
Compound 529520: Lys, TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]-6-[tert-butyl(dimethyl)silyl]oxyhexanoate. Molecular Formula: C24H55NO3Si3. Molecular Weight: 490.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525779: 2-Butyl-5-methyl-4-propyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2-butyl-5-methyl-4-propyl-1,3-oxazole. Molecular Formula: C11H19NO. Molecular Weight: 181.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Single session endoscopic management of intrinsic ureteropelvic junction obstruction and concomitant renal stone disease in a child: a case report

Background
          Percutaneous nephrolithotomy is a well known therapeutic modality for stone diseases of childhood. Antegrade and retrograde endopyelotomies are also well defined options of treatment for secondary ureteropelvic junction obstruction. Yet there are few reports regarding endoscopic therapy of intrinsic ureteropelvic junction obstruction. To our knowledge, there exist only a few reports of endosurgical treatment of children with stone disease and with concomitant intrinsic ureteropelvic junction obstruction, in the literature.
        
        
          Case presentation
          We present the endoscopic management of stone disease and concomitant intrinsic ureteropelvic junction obstruction of a child in one session.
        
        
          Conclusion
          Percutaneous nephrolithotomy and antegrade endopyelotomy is combined safely with successful outcome in a child.
Compound 528994: Hexacosane, 1,2-bis(methylthio)

Chemical compound data from PubChem database. IUPAC Name: 1,2-bis(methylsulfanyl)hexacosane. Molecular Formula: C28H58S2. Molecular Weight: 458.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
End-Stage Renal Disease Facility Aggregation Group Performance

The End-Stage Renal Disease (ESRD) Facility Aggregation Group Performance dataset provides performance information in the End-Stage Renal Disease (ESRD) Treatment Choices (ETC) Model. The dataset includes information on Performance Payment Adjustment (PPA), Modality Performance Score (MPS), home dialysis rate, and transplant rate, as well as the individual components of each rate for each model participant ESRD facility aggregation group.

 

All ESRD facilities within the same aggregation group share the same performance information. The supplementary aggregation group crosswalk file may be used to map aggregation groups to individual ETC Participant ESRD facilities.
NSDUH 2023 Methodological Resource Book (MRB)

Use this collection to provide context for estimates from the National Survey on Drug Use and Health (NSDUH). This collection includes materials used to conduct the survey, reports on how the survey was conducted, and reports on how the data were processed. The Statistical Inference Report details how the data were analyzed for reports and tables, which may be useful for data users looking to do their own analysis.New items are added to the collection as they become available, so resources published in a previous MRB may not yet be available for 2023. However, there are generally few changes from year to year, and a report from a previous year may have the information you are looking for.
Respiratory Virus Wastewater Surveillance

Concentrations of respiratory viruses in the Chicago sewer system as measured at seven sewershed sites since February 2022. In addition to SARS-CoV-2 (the virus that causes COVID-19), concentration data is also available for Respiratory Syncytial Virus (RSV), and influenza virus (types A and B). 

Generally, two samples are collected from each site during each week of the year. Concentration data reflect within-site and overall averages of this data each week. Because respiratory viruses are shed in human feces, tracking this data can help predict changes in disease trends and better understand the epidemiology of these common respiratory viruses in Chicago.

Please note that one of the "sites" listed is "All sites," which combines the individual sites. Care should be taken when summing or otherwise aggregating rows to avoid double counting.

These data are updated weekly and displayed on the Chicago Department of Public Health’s <a href="https://www.chicago.gov/city/en/depts/cdph/supp_info/infectious/respiratory-illness/respiratory-illness-data.html" target="_blank">Respiratory Illness Dashboard</a>.

This dataset replaces <a href="https://data.cityofchicago.org/d/urdi-w8wq" target = "_blank">COVID-19 Wastewater Detection</a>, which will no longer be updated. See https://data.cityofchicago.org/stories/s/Wastewater-Surveillance-Datasets-3-5-2025/sihu-d8va for more information.
ICUs worldwide: Results of a nationwide survey of Colombian intensive care units

Sixty-three of 89 identified intensive care units in Colombia (Evaluation of Intensive Care in Colombia) participated in this voluntary study. A convenience sample of 20 intensive care units, each submitting 200 patients or more, was chosen, from which the following information is presented. The Intensive Care National Audit and Research Center (UK) protocol was used to evaluate patient severity, length of stay, raw and anticipated mortality, intensive care unit patient admission/rejection criteria, and human and technologic resources available. Information was drawn from public and private institutions.
Compound 525525: (3-Chloro-4-cyclohexylmethoxy-phenyl)-acetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[3-chloro-4-(cyclohexylmethoxy)phenyl]acetate. Molecular Formula: C16H21ClO3. Molecular Weight: 296.79. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
New York State Statewide COVID-19 Admissions by Zip Code (Archived)

<b>Note:</b> Data elements were retired from HERDS on 10/6/23 and this dataset was archived.

This dataset includes information at the report date level on patients admitted for inpatient care to the hospital that are lab-confirmed COVID-19 positive.  Admitted means that the patient was newly admitted to the hospital or was confirmed positive after admission.  Zip Code information became available for COVID-19 admissions as of May 2, 2020.  Hospitalized means patients admitted as inpatients in either inpatient or observation beds and does not include patients that were treated and released from an Emergency Department. The title of this dataset was initially the Hospital Electronic Response Data System (HERDS) Hospital Survey: COVID-19 Admissions by Zip Code. The dataset was changed to its current title on 11/4/2021.
2010 State Profile — Pennsylvania

This state profile includes data from facilities in Pennsylvania that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Pennsylvania. In Pennsylvania, 533 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 51,302 clients in substance abuse treatment on March 31, 2010. The survey response rate in Pennsylvania was 93.4%.
New York City – 5 Boros: Drug-Related Emergency Department Visits, 2004-2011 - All Alcohol

Excel file with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving alcohol in New York City (5 boroughs).  For adults aged 21 and older, the alcohol was found in combination with other drugs. For patients under the age of 21, the visit may involve alcohol alone or in combination with other drugs.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.
Compound 527142: 2-Methyl-5-prop-1-en-2-ylcyclohexa-2,4-dien-1-ol

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-5-prop-1-en-2-ylcyclohexa-2,4-dien-1-ol. Molecular Formula: C10H14O. Molecular Weight: 150.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525804: N-(4-Methylphenyl)-N'-(4-ethoxyphenyl)formamidine

Chemical compound data from PubChem database. IUPAC Name: N-(4-ethoxyphenyl)-N'-(4-methylphenyl)methanimidamide. Molecular Formula: C16H18N2O. Molecular Weight: 254.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E40121-T1: [Translated] N-(AZOLYLCARBAMOYL)-HYDROXYLAMINE AND FUNGICIDES CONTAINING THEM.

N-(Azolylcarbamyl)-hydroxylamines of the formula    <IMAGE>  (I) where R is unsubstituted or substituted alkyl, alkenyl, alkoxyalkyl or cycloalkyl, or unsubstituted or substituted phenyl, phenylalkyl, phenylalkenyl or phenoxyalkyl, R1 is alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, cycloalkylalkyl or unsubstituted or substituted benzyl, Y is CH or N and R2 and R3 are each hydrogen or alkyl, and fungicides which contain these compounds.
Warning Letters

<p>When it is consistent with the public protection responsibilities of the agency and depending on the nature of the violation, it is the Food and Drug Administration's (FDA's) practice to give individuals and firms an opportunity to take voluntary and prompt corrective action before it initiates an enforcement action. Warning Letters are issued to achieve voluntary compliance and to establish prior notice.  The use of Warning Letters and the prior notice policy are based on the expectation that most individuals and firms will voluntarily comply with the law.  See <a href="http://www.fda.gov/ICECI/ComplianceManuals/RegulatoryProceduresManual/ucm176870.htm">http://www.fda.gov/ICECI/ComplianceManuals/RegulatoryProceduresManual/uc...</a> for additional infomation on Warning Letters.</p>
National Survey Of Substance Abuse Treatment Services (N-SSATS): 2020, Data On Substance Abuse Treatment Facilities

This report presents results from the 2020 National Survey of Substance Abuse Treatment Services (N-SSATS), an annual census of facilities providing substance abuse treatment. Conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 states, the District of Columbia, and other jurisdictions. It is important to note that values in charts, narrative lists, and percentage distributions are calculated using actual raw numbers and rounded for presentation in this report; calculations using rounded values may produce different results.
Compound 527759: 2,2-Dichloroethyl heptanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl heptanoate. Molecular Formula: C9H16Cl2O2. Molecular Weight: 227.12. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400363-T1: [Translated] CATALYTIC REACTOR WITH A CATALYST SUPPORT WITH CIRCULATION CHANNEL NETWORKS

The present invention relates to a catalyst support comprising a monolithic body ( 1 ) with a first network of channels ( 2 ). According to the invention, the support comprises at least an additional network of channels ( 3 ) in an arrangement whereby channels ( 2, 3 ) of the networks intersect one another.
Compound 530692: 2,3,4-Trifluorobenzoic acid, 3-methylbut-2-enyl ester

Chemical compound data from PubChem database. IUPAC Name: 3-methylbut-2-enyl 2,3,4-trifluorobenzoate. Molecular Formula: C12H11F3O2. Molecular Weight: 244.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525479: 4-Methyl-3-thia-1-hexanethiol

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-ylsulfanylethanethiol. Molecular Formula: C6H14S2. Molecular Weight: 150.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525537: (4-Isobutoxy-phenyl)-acetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[4-(2-methylpropoxy)phenyl]acetate. Molecular Formula: C13H18O3. Molecular Weight: 222.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.