AndreaBozzo/ceres-open-data-index huggingface dataset:
NNDSS - Table II. Hepatitis (viral, acute) A & B

NNDSS - Table II. Hepatitis (viral, acute) A & B - 2017.  In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed. The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories.

Note:
These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. 

Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. 

Footnotes:
 C.N.M.I.: Commonwealth of Northern Mariana Islands. 

U: Unavailable. —: No reported cases. N: Not reportable. NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum. 

*Three low incidence conditions, rubella, rubella congenital, and tetanus, are in Table II to facilitate case count verification with reporting jurisdictions. 

† Case counts for reporting year 2017 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for tuberculosis are displayed in Table IV, which appears quarterly.
Quality of life effects of antithrombin III in sepsis survivors: results from the KyberSept trial [ISRCTN22931023]

Introduction
          Treatment of sepsis is aimed at increasing both the duration and quality of survival. A long-term focus on quality of life (QoL) in clinical trial evaluations of sepsis care should be a priority.
        
        
          Method
          QoL data were used to evaluate the effects of intravenous antithrombin III treatment for severe sepsis measured for up to 90 days during the follow-up phase of the KyberSept phase III clinical trial. A visual analog scale and a Karnofsky scale were used to measure physical, psychologic, and social QoL at regular intervals. Changes from baseline between placebo and antithrombin III groups were assessed using Wilcoxon statistical tests, with additional analyses by severity of illness and admitting diagnosis.
        
        
          Results
          Among all sepsis survivors in the trial, there was a significant advantage on some attributes of QoL in the antithrombin III subgroup of patients who did not receive heparin as compared with the corresponding placebo group.
        
        
          Discussion
          The present study represents the first attempt to evaluate patient QoL over a relatively long period in a large, randomized, placebo-controlled sepsis trial. Over a 90-day period, survivors of severe sepsis receiving antithrombin III experienced significant improvements as compared with placebo on several attributes of QoL. In conclusion, the present study demonstrated that clinical improvements over an extended time period with antithrombin III were complemented by improvements in QoL, particularly in social and psychologic functioning, in many patients.
Patent AT-E400978-T1: [Translated] DEVICE FOR ELECTROACOUSTIC RADIATION WITH MEMBRANES, CENTERING MEMBRANES AND HORNES MADE OF BALSA WOOD OR A MIXTURE THEREOF

PCT No. PCT/IT96/00117 Sec. 371 Date Nov. 21, 1997 Sec. 102(e) Date Nov. 21, 1997 PCT Filed Jun. 10, 1996 PCT Pub. No. WO97/37513 PCT Pub. Date Oct. 9, 1997A device for electroacoustic diffusion includes a basket; a balance supported by the basket, made of balsa wood or formed with a balsa wood stripe fixed at its ends with a coil glued at its middle; a balsa wood membrane supported by the basket; a suspension adjacent to the membrane and supported by the basket; and an electroacoustic structure adjacent the basket and opposite the balance. The electroacoustic structure includes a first plate adjacent the basket, a second plate, a magnet between the first plate and the second plate, and a coil between the first plate and the second plate. The membrane can take on various shapes, including: (a) a truncated-cone shape, including triangular pieces of balsa wood, steam folded, glued, and placed with fibers of the balsa wood in a radial orientation, (b) a dome-shape, and (c) a planar shape.
Illicit Drug Use Tables (Standard Errors and P Values) - 1.1 to 1.92

These detailed tables present standard errors for illicit drug use totals and prevalence estimates from the 2012 National Survey on Drug Use and Health (NSDUH). Illicit drugs include marijuana, cocaine, crack, heroin, hallucinogens, inhalants, and the nonmedical use of prescription-type psychotherapeutics, including pain relievers, tranquilizers, stimulants, and sedatives. Standard errors are provided for lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area. Standard errors are provided for both 2012 and 2011.
Compound 526225: 1,2,3,4-Tetrabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,3,4-tetrabromodibenzofuran. Molecular Formula: C12H4Br4O. Molecular Weight: 483.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525365: 2,3-Dimethyl-4-thianonane

Chemical compound data from PubChem database. IUPAC Name: 1-(3-methylbutan-2-ylsulfanyl)pentane. Molecular Formula: C10H22S. Molecular Weight: 174.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NSDUH 2022 Highlighted Population Slides

Use these slides to explore substance use and mental health measures for particular populations in the United States. The slides are based on the 2022 National Survey on Drug Use and Health (NSDUH), which is administered to civilians 12 and older not living in institutions. Within each slide deck, selected estimates are presented overall, by age group, and for selected sub-populations. Slides for the following populations are available:American Indian and Alaska Native Population (AIAN)Asian PopulationBlack or African American PopulationFemale PopulationHispanic or Latino PopulationMultiracial PopulationNative Hawaiian and Other Pacific Islander Population (NHOPI)Veteran PopulationThe slides are available as PDF or PowerPoint files.
5.2a Clients in treatment, according to type of care received, by facility operation and primary focus of facility: March 31, 2011. Number

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing clients in treatment, according to type of care received, by facility operation and primary focus of facility in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.
Observations on morphologic changes in the aging and degenerating human disc: Secondary collagen alterations

Background
          In the annulus, collagen fibers that make up the lamellae have a wavy, planar crimped pattern. This crimping plays a role in disc biomechanical function by allowing collagen fibers to stretch during compression. The relationship between morphologic changes in the aging/degenerating disc and collagen crimping have not been explored.
        
        
          Methods
          Ultrastructural studies were performed on annulus tissue from 29 control (normal) donors (aged newborn to 79 years) and surgical specimens from 49 patients (aged 16 to 77 years). Light microscopy and specialized image analysis to visualize crimping was performed on additional control and surgical specimens. Human intervertebral disc tissue from the annulus was obtained in a prospective morphologic study of the annulus. Studies were approved by the authors' Human Subjects Institutional Review Board.
        
        
          Results
          Three types of morphologic changes were found to alter the crimping morphology of collagen: 1) encircling layers of unusual matrix disrupted the lamellar collagen architecture; 2) collagen fibers were reduced in amount, and 3) collagen was absent in regions with focal matrix loss.
        
        
          Conclusions
          Although proteoglycan loss is well recognized as playing a role in the decreased shock absorber function of the aging/degenerating disc, collagen changes have received little attention. This study suggests that important stretch responses of collagen made possible by collagen crimping may be markedly altered by morphologic changes during aging/degeneration and may contribute to the early tissue changes involved in annular tears.
Compound 526189: Dihydro-2-methoxy-2-methyl-3(2H)-thiophenone

Chemical compound data from PubChem database. IUPAC Name: 2-methoxy-2-methylthiolan-3-one. Molecular Formula: C6H10O2S. Molecular Weight: 146.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526541: Heliotrine (7R)

Chemical compound data from PubChem database. IUPAC Name: (6-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl)methyl 2-hydroxy-2-(1-methoxyethyl)-3-methylbutanoate. Molecular Formula: C16H27NO5. Molecular Weight: 313.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Comparison of the sensitivity of a 24 h-shell vial assay, and conventional tube culture, in the isolation of Herpes simplex virus – 1 from corneal scrapings

Background
          Herpes simplex keratitis is a sight threatening ocular infection. A rapid and specific diagnosis is essential for the institution of specific antiviral therapy and to avoid complications that can arise from misdiagnosis and inappropriate treatment. Though a variety of techniques are available, isolation of Herpes simplex virus 1 (HSV-1) in culture provides the most reliable and specific method, and is considered as the gold standard in laboratory diagnosis of herpes simplex keratitis. We report a comparative study of the sensitivity of a 24 h-shell vial assay and conventional tube culture in the isolation of HSV-1 from corneal scrapings.
        
        
          Methods
          A total of 74 corneal scrapings obtained from 74 patients with a clinical suspicion of herpes simplex keratitis submitted for the isolation of HSV-1, were simultaneously inoculated into shell vial and tube cultures employing the vero cell line. Shell vial and tube cultures were terminated at 24 h and fifth day respectively. Isolation of HSV-1 was confirmed employing an indirect immunofluorescence assay.
        
        
          Results
          HSV-1 was isolated from 24/74 (32.4%) specimens employing both the methods. Sensitivity of both the techniques were found to be similar (20/24, 83.3%) (P = 1.0).
        
        
          Conclusion
          A 24 h-shell vial assay is a rapid alternative technique in comparison to the time consuming conventional tube cultures for the isolation of HSV-1, especially from corneal scrapings for the laboratory diagnosis of herpes simplex keratitis.
Patent AT-E40000-T1: [Translated] PLANT FOR COOLING PRODUCTS UNDER VACUUM.

Method of operating an installation for refrigerating products under vacuum, such as lettuce, which installation comprises a closable vessel for the products, one or more vacuum pumps adapted to produce a vacuum in the interior of the vessel, a water vapour condenser (1) disposed in the vessel through which a refrigerant can be passed, and a refrigerating unit comprising a compressor (7), a condenser (9) and a throttle valve (13), disposed outside the vessel and an evaporator being formed by said water vapour condenser (1) disposed in the vessel, whereby a low-pressure separator (3) is provided for liquid and vaporous refrigerant, the suction pipe (6) of the compressor (7) and the outlet pipe (14) of the throttle valve (13), as well as the two pipes (2 and 4) of the water vapour condenser (1), being connected to said separator, while a high-pressure vessel (11) for liquid refrigerant is disposed between the refrigerant condenser (9) and the throttle valve (13), whereby the compressor (7) is brought into action, with the throttle valve (13) open, approximately simultaneously with the vacuum pump or pumps and the throttle valve (13) is closed at reaching the evaporation temperature of the water in the product.
Compound 527115: 1-Butanamine, 3-methyl, N-(2-methylpropyl)

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-N-(2-methylpropyl)butan-1-amine. Molecular Formula: C9H21N. Molecular Weight: 143.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525046: Quininic acid (5TMS)

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 1,3,4,5-tetrakis(trimethylsilyloxy)cyclohexane-1-carboxylate. Molecular Formula: C22H52O6Si5. Molecular Weight: 553.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526183: 1,3-Dithiolo[4,5-b]furan, tetrahydro-3a-methyl-

Chemical compound data from PubChem database. IUPAC Name: 3a-methyl-6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan. Molecular Formula: C6H10OS2. Molecular Weight: 162.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530314: Hexadecanoic acid, 14-methyl-2-trimethylsilyloxy, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 14-methyl-2-trimethylsilyloxyhexadecanoate. Molecular Formula: C21H44O3Si. Molecular Weight: 372.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525364: 2,3-Dimethyl-4-thiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-3-propylsulfanylbutane. Molecular Formula: C8H18S. Molecular Weight: 146.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2011-2012 NSDUH State Prevalence Estimates - PDF Tables (for printing)

2011-2012 NSDUH State Prevalence Estimates – PDF Tables formatted for printing. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Results are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
COVID-19 State Profile Report - Missouri

<b>After over two years of public reporting, the State Profile Report will no longer be produced and distributed after February 2023. The final release was on February 23, 2023. We want to thank everyone who contributed to the design, production, and review of this report and we hope that it provided insight into the data trends throughout the COVID-19 pandemic.
Data about COVID-19 will continue to be updated at <a href='https://covid.cdc.gov/covid-data-tracker/#datatracker-home' >CDC’s COVID Data Tracker</a>.
 </b>

<p>
The State Profile Report (SPR) is generated by the Data Strategy and Execution Workgroup in the Joint Coordination Cell, in collaboration with the White House. It is managed by an interagency team with representatives from multiple agencies and offices (including the United States Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention, the HHS Assistant Secretary for Preparedness and Response, and the Indian Health Service). The SPR provides easily interpretable information on key indicators for each state, down to the county level.
 </p>

It is a weekly snapshot in time that:
<ul>
<li>Focuses on recent outcomes in the last seven days and changes relative to the month prior</li>
<li>Provides additional contextual information at the county level for each state, and includes national level information</li>
<li>Supports rapid visual interpretation of results with color thresholds</li>
</ul>
Compound 529035: 5-Ethyl-2-pentyl-1,3,2-dioxaborolan-4-one

Chemical compound data from PubChem database. IUPAC Name: 5-ethyl-2-pentyl-1,3,2-dioxaborolan-4-one. Molecular Formula: C9H17BO3. Molecular Weight: 184.04. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527836: Butyl N-(trifluoroacetyl)-alpha-aminoisobutyrate

Chemical compound data from PubChem database. IUPAC Name: butyl 2-methyl-2-[(2,2,2-trifluoroacetyl)amino]propanoate. Molecular Formula: C10H16F3NO3. Molecular Weight: 255.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400704-T1: [Translated] ROAD CROSSING

The road joint incorporates elastic profiles (1), which are installed so that they are constantly under pressure regardless of the position of the road joint. The contact surface (7) between each elastic profile and a center profile (2) or edge profile (3) extends from an edge of each individual joint gap in the vehicle-carrying surface (6), in an angled downward direction towards the center or edge profile concerned. The elastic profiles are of an extruded elastomer, and they have hollow chambers (11) filled with a gaseous medium.
Treatment Episode Data Set (TEDS): 1999-2009, National Admissions to Substance Abuse Treatment Services

This report presents data from the Treatment Episode Data Set (TEDS) for 2009, and trend data for 1999 to 2009. The report provides information on the demographic and substance abuse characteristics of people aged 12 and older admitted to treatment for abuse of alcohol and/or drugs in facilities that report to individual state administrative data systems.
COVID-19 State Profile Report - Vermont

<b>After over two years of public reporting, the State Profile Report will no longer be produced and distributed after February 2023. The final release was on February 23, 2023. We want to thank everyone who contributed to the design, production, and review of this report and we hope that it provided insight into the data trends throughout the COVID-19 pandemic.
Data about COVID-19 will continue to be updated at <a href='https://covid.cdc.gov/covid-data-tracker/#datatracker-home' >CDC’s COVID Data Tracker</a>.
 </b>

<p>
The State Profile Report (SPR) is generated by the Data Strategy and Execution Workgroup in the Joint Coordination Cell, in collaboration with the White House. It is managed by an interagency team with representatives from multiple agencies and offices (including the United States Department of Health and Human Services (HHS), the Centers for Disease Control and Prevention, the HHS Assistant Secretary for Preparedness and Response, and the Indian Health Service). The SPR provides easily interpretable information on key indicators for each state, down to the county level.
 </p>

It is a weekly snapshot in time that:
<ul>
<li>Focuses on recent outcomes in the last seven days and changes relative to the month prior</li>
<li>Provides additional contextual information at the county level for each state, and includes national level information</li>
<li>Supports rapid visual interpretation of results with color thresholds</li>
</ul>
Compound 528894: Dipropylbarbituric acid M (OH), #2

Chemical compound data from PubChem database. IUPAC Name: 5-(2-hydroxypropyl)-5-propyl-1,3-diazinane-2,4,6-trione. Molecular Formula: C10H16N2O4. Molecular Weight: 228.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527090: 2,6,10,19,23-Pentamethyltetracosa-2,6,10,14,18,22-hexaene

Chemical compound data from PubChem database. IUPAC Name: 2,6,10,19,23-pentamethyltetracosa-2,6,10,14,18,22-hexaene. Molecular Formula: C29H48. Molecular Weight: 396.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Pharmacokinetics of artesunate after single oral administration to rats

Background
          Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate following oral administration in rats, samples were collected at baseline, and then 0.5, 2, 5, 10, 15, 30, 45, 60 and 120 minutes after a single dose of 150 mg.
        
        
          Results
          Peak concentration of parent artesunate and dihydroartemisinin was achieved within 5 and 37.5 +/- 8.7 min, respectively of start of administration through gavage. The half lives of absorption were 2.73 +/- 0.85 and 12.49 +/- 2.49 min, respectively.
        
        
          Conclusions
          These times were considerably shorter for artesunate than those found in studies which start sampling later. The profiles of parent compound and metabolite result from a complex equation dictated by the pH-dependent rates of hydroxylation of artesunate to dihydroartemisinin, the different rates at which either compounds are absorbed, and the catalytic hydroxylation by esterases. The rate of chemical oxidation of artesunate is pH dependent; this explains its rapid conversion to dihydroartemisinin in the stomach, as compared to its greater stability in other compartments at higher pH and in plasma. We propose that variable proportions of absorption take place in the stomach, and conclude that parent artesunate reaches an early peak within minutes of dosing, and that the early dihydroartemisinin levels result primarily from the absorption of the metabolite as such.