AndreaBozzo/ceres-open-data-index huggingface dataset:
Rate PUF - PY2016

The Rate PUF (Rate-PUF) is one of the seven files that make up the Marketplace PUF. The Rate-PUF contains plan-level data on individual rates based on an eligible subscriber’s age, tobacco use, and geographic location. These data either originate from the Rate Table template (i.e., template field), an Excel based form used by issuers to describe their plans in the QHP/SADP application process, or were generated by CCIIO for use in data processing (i.e., system-generated).
New Hampshire (NH)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for New Hampshire overall and for substate regions within New Hampshire. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Dr. Elinore F. McCance-Katz, Urgent and Emerging Issues in Prevention: Marijuana, Kratom, E-cigarettes

SAMHSA Prevention Day, February 4, 2019 Elinore F. McCance-Katz, MD, PhD, Assistant Secretary for Mental Health and Substance Use, Substance Abuse and Mental Health Services Administration, Department of Health and Human ServicesView therecorded presentation(link is external)and webcast slides (PDF,PPTX) presented by Dr. Elinore F. McCance-Katz.
Quantitation ofPseudomonas aeruginosain wound biopsy samples: from bacterial culture to rapid `real-time' polymerase chain reaction

Early diagnosis of wound colonisation or prediction of wound sepsis provides an opportunity for therapeutic intervention. There is need for qualitative and quantitative tests that are more rapid than bacterial culture.Pseudomonas aeruginosaresults in high morbidity and mortality rates, is inherently resistant to common antibiotics, and is increasingly being isolated as a nosocomial pathogen. We developed three PCR-based methods to detect and quantifyP aeruginosain wound biopsy samples: conventional PCR, enzyme-linked immunosorbent assay (ELISA)-PCR, and RTD-PCR with rapid thermal cycling (LightCycler™technology), all based on the amplification of the outer membrane lipoprotein geneoprL. We compared the efficacy of these methods to bacterial culture by quantitatively measuring levels ofP aeruginosain serial dilutions, in reconstituted skin samples and 21 burn wound biopsy samples.
A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion

Background
          Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal function. Luteinizing hormone secretion is regulated both by alterations in gonadotrope responsiveness to hypothalamic gonadotropin releasing hormone and by alterations in gonadotropin releasing hormone secretion. The mechanisms that determine gonadotrope responsiveness are unknown but may involve regulators of G protein signaling (RGSs). These proteins act by antagonizing or abbreviating interaction of Gα proteins with effectors such as phospholipase Cβ. Previously, we reported that gonadotropin releasing hormone-stimulated second messenger inositol trisphosphate production was inhibited when RGS3 and gonadotropin releasing hormone receptor cDNAs were co-transfected into the COS cell line. Here, we present evidence for RGS3 inhibition of gonadotropin releasing hormone-induced luteinizing hormone secretion from cultured rat pituitary cells.
        
        
          Results
          A truncated version of RGS3 (RGS3T = RGS3 314–519) inhibited gonadotropin releasing hormone-stimulated inositol trisphosphate production more potently than did RSG3 in gonadotropin releasing hormone receptor-bearing COS cells. An RSG3/glutathione-S-transferase fusion protein bound more 35S-Gqα than any other member of the G protein family tested. Adenoviral-mediated RGS3 gene transfer in pituitary gonadotropes inhibited gonadotropin releasing hormone-stimulated luteinizing hormone secretion in a dose-related fashion. Adeno-RGS3 also inhibited gonadotropin releasing hormone stimulated 3H-inositol phosphate accumulation, consistent with a molecular site of action at the Gqα protein.
        
        
          Conclusions
          RGS3 inhibits gonadotropin releasing hormone-stimulated second messenger production (inositol trisphosphate) as well as luteinizing hormone secretion from rat pituitary gonadotropes apparently by binding and suppressing the transduction properties of Gqα protein function. A version of RGS3 that is amino-terminally truncated is even more potent than intact RGS3 at inhibiting gonadotropin releasing hormone-stimulated inositol trisphosphate production.
Compound 529528: Methyl (2Z)-3,3,3-trifluoro-2-(4H-indeno[2,1-d][1,3]oxathiol-2-ylidene)propanoate

Chemical compound data from PubChem database. IUPAC Name: 1,2-difluorophenanthrene. Molecular Formula: C14H8F2. Molecular Weight: 214.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hospital Cost Report Audited Data Print Image: 2013

This print image version of the Institutional Cost Report (ICR) has been audited by the DOH. is the Institutional Cost Report (ICR) is a uniform report completed by New York hospitals to report income, expenses, assets, liabilities, and statistics to the Department of Health (DOH). Under DOH regulations, (Part 86-1.2), Article 28 hospitals are required to file financial and statistical data with DOH annually. The data filed is part of the ICR and is received electronically through a secured network. This data is used to develop Medicaid rates, assist in the formulation of reimbursement methodologies, and analyze trends. For more information, check out: http://www.health.ny.gov/facilities/hospital/index.htm.
Patent AT-E400920-T1: [Translated] CONTROL CIRCUIT FOR AN ELECTRONICALLY COMMUTATED MOTOR

A control circuit for an electronically commutated motor (120), having a power stage (122) that comprises at least two semiconductor switches (216, 218) to influence the motor current. The semiconductor switches are controllable by way of commutation signals. The control circuit comprises a current measuring element (170) to make available a motor current control variable (I) dependent on the motor current, a base diode (240) that is arranged in series with the current measuring element and between the current measuring element and the at least two semiconductor switches, and a motor current setting element (180) with which the commutation signals can be influenced as a function of the motor current control variable.
Patent AT-E401649-T1: [Translated] INITIALIZATION OF A PHASE CHANGE TYPE OPTICAL RECORDING MEDIUM

A method of initializing a phase-change optical information recording medium is provided, using an optical system incorporating a semiconductor laser device. The laser device is characterized by a specified spatial power distribution. In a spatial distribution of the laser power focused on the recording medium in the direction perpendicular to guide tracks, the laser device preferably has an average smaller in both end regions of the spatial distribution, which have each 10% of the width at half maximum of the distribution, than the average in the center region of the full width at half maximum of the distribution. <IMAGE>
Compound 526708: trans-4,5-epoxy-2(E)-Decenal

Chemical compound data from PubChem database. IUPAC Name: 3-(3-pentyloxiran-2-yl)prop-2-enal. Molecular Formula: C10H16O2. Molecular Weight: 168.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528594: Protocatechuic acid, TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 3,4-bis[[tert-butyl(dimethyl)silyl]oxy]benzoate. Molecular Formula: C25H48O4Si3. Molecular Weight: 496.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400596-T1: [Translated] PRODUCTION OF FUNCTIONAL POLYOLEFIN MASTERBATCH AND THEIR USE

The present invention belongs to the field of polymerization and processing of polymer and relates to the preparation of a kind of functional polyolefin master batch. The functional master batch is produced by liquid phase, melt phase, or solid phase reaction after mixing the polyolefin resin, polyamine and guanidine salt oligomer, olefin monomer and initiator. The molecular structure of functional polyolefin master batch is shown below: <CHEM> wherein R is a polyamine and guanidine salt oligomer bonded onto polyolefin molecular chain by covalence bond, while S is one selected from hydrogen, chlorine, methyl, or phenyl group. <??>Blending mentioned functional master batch with the corresponding polyolefin, the various antimicrobe products, such as fibers, film, pipe and other plastic articles can be obtained. Besides endowing products with excellent permanent antimicrobe property, it also provides fibers with good-dyeable and antistatic ability and bumpers with easy-paintable ability.
Abdominal compartment syndrome: does intra-cystic pressure reflect actual intra-abdominal pressure? A prospective study in surgical patients

Background:
          Abdominal compartment syndrome is defined as the adverse physiologic effects of increased intra-abdominal pressure. Prolonged, unrelieved pressure may lead to respiratory compromise, renal impairment, cardiac failure, shock, and death. Abdominal compartment syndrome is diagnosed by measuring intra-cystic pressure as a reflection of intra-abdominal pressure. To examine the validity of the technique, we conducted a prospective study in surgical patients by directly measuring bladder and abdominal pressures simultaneously during laparoscopic cholecystectomy using a previously described technique.
        
        
          Results:
          In the present model, the bladder had higher baseline pressures than did the abdomen. Measurements across the bladder wall were not identical, but had high positive correlation coefficient when evaluated on an individual basis. Global analysis of the data for all patients showed a weak correlation coefficient.
        
        
          Conclusion:
          In the present study model, intra-cystic pressure did not reflect actual intra-abdominal pressure. In spite of some limitations in the study design, we feel that further research is warranted to identify other possible variables that may play a role in the relationship between the urinary bladder and the abdominal cavity pressures, providing better means for diagnosis of abdominal compartment syndrome.
Youth Tobacco Survey: Beginning 2000

The Youth Tobacco Survey (YTS) was developed by the Centers for Disease Control and Prevention (CDC) in collaboration with U.S. states to provide trend surveillance in youth tobacco use, access, and perceptions. The New York State Department of Health has conducted this survey biennially since 2000 in order to monitor trends related to the objectives of the Bureau of Tobacco Control and to evaluate the aggregate effects of various interventions.
Compound 528324: Pyrazine, 3-phenylthio-2-propyl

Chemical compound data from PubChem database. IUPAC Name: 2-phenylsulfanyl-3-propylpyrazine. Molecular Formula: C13H14N2S. Molecular Weight: 230.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527223: Heptanoic acid, 2-iodoethyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-iodoethyl heptanoate. Molecular Formula: C9H17IO2. Molecular Weight: 284.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528878: Tyr, TFE-PFP

Chemical compound data from PubChem database. IUPAC Name: [4-[3-oxo-2-(2,2,3,3,3-pentafluoropropanoylamino)-3-(2,2,2-trifluoroethoxy)propyl]phenyl] 2,2,3,3,3-pentafluoropropanoate. Molecular Formula: C17H10F13NO5. Molecular Weight: 555.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NCHS - Drug Poisoning Mortality by State: United States

This dataset describes drug poisoning deaths at the U.S. and state level by selected demographic characteristics, and includes age-adjusted death rates for drug poisoning from 1999 to 2015.

Deaths are classified using the International Classification of Diseases, Tenth Revision (ICD–10). Drug-poisoning deaths are defined as having ICD–10 underlying cause-of-death codes X40–X44 (unintentional), X60–X64 (suicide), X85 (homicide), or Y10–Y14 (undetermined intent).

Estimates are based on the National Vital Statistics System multiple cause-of-death mortality files (1). Age-adjusted death rates (deaths per 100,000 U.S. standard population for 2000) are calculated using the direct method. Populations used for computing death rates for 2011–2015 are postcensal estimates based on the 2010 U.S. census. Rates for census years are based on populations enumerated in the corresponding censuses. Rates for noncensus years before 2010 are revised using updated intercensal population estimates and may differ from rates previously published.

Estimate does not meet standards of reliability or precision. Death rates are flagged as “Unreliable” in the chart when the rate is calculated with a numerator of 20 or less.

Death rates for some states and years may be low due to a high number of unresolved pending cases or misclassification of ICD–10 codes for unintentional poisoning as R99, “Other ill-defined and unspecified causes of mortality” (2). For example, this issue is known to affect New Jersey in 2009 and West Virginia in 2005 and 2009 but also may affect other years and other states. Estimates should be interpreted with caution.

Smoothed county age-adjusted death rates (deaths per 100,000 population) were obtained according to methods described elsewhere (3–5). Briefly, two-stage hierarchical models were used to generate empirical Bayes estimates of county age-adjusted death rates due to drug poisoning for each year during 1999–2015. These annual county-level estimates “borrow strength” across counties to generate stable estimates of death rates where data are sparse due to small population size (3,5). Estimates are unavailable for Broomfield County, Colo., and Denali County, Alaska, before 2003 (6,7). Additionally, Bedford City, Virginia was added to Bedford County in 2015 and no longer appears in the mortality file in 2015. County boundaries are consistent with the vintage 2005-2007 bridged-race population file geographies (6).
Compound 526112: 7-[5-Hydroxy-3-oxo-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid

Chemical compound data from PubChem database. IUPAC Name: 7-[5-hydroxy-3-oxo-2-(3-oxooct-1-enyl)cyclopentyl]hept-5-enoic acid. Molecular Formula: C20H30O5. Molecular Weight: 350.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400262-T1: [Translated] USE OF COMPOSITIONS CONTAINING OLEANIC ACID AND URSOLIC ACID FOR PREPARING A MEDICATION FOR THE TREATMENT OF HYPERSENSITIVITY AND HYPERREACTIVITY

A material comprising from 30 to 80% by weight of ursolic acid, from 2 to 25% by weight of oleanolic acid and from 1 to 68% by weight of triterpenoic acids other than ursolic acid or oleanolic acid, or derivatives of any of these acids, said percentages being based on total weight of said acids or derivatives and the percentages of said acids or derivatives adding up to 100%, can be used in the prevention or treatment of hypersensitivity and/or hyper-reactivity.
Chemokines and their role in airway hyper-reactivity

Airway hyper-reactivity is a characteristic feature of many inflammatory lung diseases and is defined as an exaggerated degree of airway narrowing. Chemokines and their receptors are involved in several pathological processes that are believed to contribute to airway hyper-responsiveness, including recruitment and activation of inflammatory cells, collagen deposition and airway wall remodeling. These proteins are therefore thought to represent important therapeutic targets in the treatment of airway hyper-responsiveness. This review highlights the processes thought to be involved in airway hyper-responsiveness in allergic asthma, and the role of chemokines in these processes. Overall, the application of chemokines to the prevention or treatment of airway hyper-reactivity has tremendous potential.
Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DAN

This commentary is a concise discussion of the interactions between bone morphogenetic proteins (BMPs) and their binding proteins in bone and cartilage morphogenesis. BMPs are a family of growth and differentiation factors, and they act on mesenchymal cells to induce cartilage and bone differentiation in concentration-dependent thresholds. The BMP–BMP receptor binding leads to a cascade of signaling and transcription of BMP response genes. BMP binding proteins, noggin, chordin and DAN, act as antagonists and determine the bioavailability of BMPs for binding to cognate receptors to elicit the biological response. Noggin null mice with unrestricted action of BMPs exhibit defects in joint morphogenesis. BMPs and their binding proteins may reciprocally regulate the dynamic topography of joints, muscle, tendons and ligaments during morphogenesis of the skeleton. In addition, BMP actions may be potentiated by twisted gastrulation. BMPs and their binding proteins may play a critical role in regeneration of cartilage in osteoarthritis.
Tribal Courts and Child Welfare: Partnering With Tribal Social Services

This Child Welfare Information Gateway Podcast is available on Apple Podcasts
  
  

, GooglePlay
  
  

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Metadata-only record linking to the original dataset. Open original dataset below.
Compound 530177: Trimethylsilyl 2-[[4-(trimethylsilylamino)benzoyl]amino]acetate

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-[[4-(trimethylsilylamino)benzoyl]amino]acetate. Molecular Formula: C15H26N2O3Si2. Molecular Weight: 338.55. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins

Background
          A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the identification of the complete mRNA and of the gene, the product of which was termed "brain cell membrane protein 1" (BCMP1).
        
        
          Results
          The 4 kb-long mRNA sequence exhibited an open-reading frame of only 543 b followed by a 3.2 kb-long 3' untranslated region containing several AUUUA instability motifs. Analysis of the encoded protein sequence identified the presence of four putative transmembrane domains. Similarity searches in protein domain databases identified partial sequence conservations with peripheral myelin protein 22 (PMP22)/ epithelial membrane proteins (EMPs) and Claudins, defining the encoded protein as representative of the existence of a novel subclass in this protein family.
          Northern-blot analysis of the expression of the corresponding mRNA in adult dog tissues revealed the presence of a huge amount of the 4 kb transcript in the brain. An EGFP-BCMP1 fusion protein expressed in transfected COS-7 cells exhibited a membranous localization as expected. The sequences encoding BCMP1 were assigned to chromosome X in dog, man and rat using radiation hybrid panels and were partly localized in the currently available human genome sequence.
        
        
          Conclusions
          We have identified the existence in several mammalian species of a gene encoding a putative four-transmembrane protein, BCMP1, wich defines a novel subclass in this family of proteins. In dog at least, the corresponding mRNA is highly present in brain cells. The chromosomal localization of the gene in man makes of it a likely candidate gene for X-linked mental retardation.
Compound 528188: 1,3-Cyclopentadiene, 5-propyl

Chemical compound data from PubChem database. IUPAC Name: 5-propylcyclopenta-1,3-diene. Molecular Formula: C8H12. Molecular Weight: 108.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528978: 1,2-Heptadecanediol, di-TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(1-trimethylsilyloxyheptadecan-2-yloxy)silane. Molecular Formula: C23H52O2Si2. Molecular Weight: 416.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527542: InChI=1/C11H19N/c1-9-6-7-10(2)12(9)8-11(3,4)5/h6-7H,8H2,1-5H

Chemical compound data from PubChem database. IUPAC Name: 1-(2,2-dimethylpropyl)-2,5-dimethylpyrrole. Molecular Formula: C11H19N. Molecular Weight: 165.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525258: N''-Isobutyl-N,N,N',N'-tetramethyl-guanidine

Chemical compound data from PubChem database. IUPAC Name: 1,1,3,3-tetramethyl-2-(2-methylpropyl)guanidine. Molecular Formula: C9H21N3. Molecular Weight: 171.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528844: Glycerol, 2,3-dimethyl, 1-octadecanoate

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethoxypropyl octadecanoate. Molecular Formula: C23H46O4. Molecular Weight: 386.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Certified Health IT Product List (CHPL)

The Certified Health IT Product List (CHPL) is a comprehensive and authoritative listing of all certified Health Information Technology which has been successfully tested and certified by the ONC Health IT Certification program. All products listed on the CHPL have been tested by an ONC-Accredited Testing Laboratory (ONC-ATL) and certified by an ONC-Authorized Certification Body (ONC-ACB) to meet criteria adopted by the Secretary of the Department of Health and Human Services (HHS).