AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E4002-T1: [Translated] DISTRIBUTORS FOR TWO-PHASE MIXTURES, PARTICULARLY WATER-STEAM MIXTURES IN FORCED-FLOW BOILERS.

Distributor for two-phase mixtures, including a distributor drum, a feed tube leading into the distributor drum in a given direction, a plurality of outlet tubes leading from the distributor drum at an angle to the given direction, and a flat baffle plate being disposed in the distributor drum at a right angle to the given direction, the baffle plate having an edge leading symmetrically and smoothly to the outlet tubes.
Compound 526677: Methyl 3,6-bis(acetyloxy)cholan-24-oate

Chemical compound data from PubChem database. IUPAC Name: methyl 4-(3,6-diacetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate. Molecular Formula: C29H46O6. Molecular Weight: 490.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526668: Ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate

Chemical compound data from PubChem database. IUPAC Name: ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate. Molecular Formula: C16H21NO2. Molecular Weight: 259.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Microarray profile of differentially expressed genes in a monkey model of allergic asthma

Background
          Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary inflammatory infiltrate. To identify genes involved in this process, the gene-expression pattern of allergic monkey lungs was profiled by microarrays. Monkeys were challenged by inhalation of A. suum antigen or given interleukin-4 (IL-4) treatment; lung tissue was collected at 4, 18 or 24 h after antigen challenge or 24 h after IL-4. Each challenged monkey lung was compared to a pool of normal, unchallenged monkey lungs.
        
        
          Results
          Of the approximately 40,000 cDNAs represented on the microarray, expression levels of 169 changed by more than 2.5-fold in at least one of the pairwise probe comparisons; these cDNAs encoded 149 genes, of which two thirds are known genes. The largest number of regulated genes was observed 4 h after challenge. Confirmation of differential expression in the original tissue was obtained for 95% of a set of these genes using real-time PCR. Cluster analysis revealed at least five groups of genes with unique expression patterns. One cluster contained genes for several chemokine mediators including eotaxin, PARC, MCP-1 and MCP-3. Genes involved in tissue remodeling and antioxidant responses were also identified as regulated by antigen and IL-4 or by antigen only.
        
        
          Conclusion
          This study provides a large-scale profile of gene expression in the primate lung following allergen or IL-4 challenge. It shows that microarrays, with real-time PCR, are a powerful tool for identifying and validating differentially expressed genes in a disease model.
Indicators for 2015B

For January 1, 2015 through March 31, 2015, the PFS update was set at 0.0 percent by the Protecting Access to Medicare Act. After applying the budget neutrality adjustment of 0.9981, the conversion factor for January 1, 2015, through March 31, 2015 is $35.7547. Under the provisions of current law regarding the SGR, the conversion factor will change to $28.1872 on April 1, 2015 in the absence of Congressional action. In addition, the geographic practice cost index work floor of 1.0 expires on March 31, 2015 in the absence of legislative action.
Compound 526250: 1,2,6,9-Tetrabromo-3,8-dichloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 1,2,6,9-tetrabromo-3,8-dichlorodibenzo-p-dioxin. Molecular Formula: C12H2Br4Cl2O2. Molecular Weight: 568.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Esomeprazole magnesium

Esomeprazole Magnesium is a generic prescription drug that reduces stomach acid production, helping treat conditions like acid reflux, ulcers, and heartburn. Available as 20mg and 40mg delayed-release capsules for oral use, it's manufactured by Mylan Pharmaceuticals Inc. under ANDA078936. This information was generated using AI and is provided for informational and research purposes only.
NCCAN 16 Plenary Session IV

This resource provides a transcript of Plenary Session IV of the 16th National Conference on Child Abuse and Neglect.

The Honorable Stephen M. Rubin describes how one community used collaboration over a ten-year period to reform its child welfare system totally. He explores the annual goals of the collaboration, as well as the process implemented to realize these goals across multiple systems. Judge Rubin, a practicing lawyer for 12 years prior to his appointment to the Pima County Bench in 1987, has served as an Adjunct Professor of Law at the University of Arizona College of Law; as co-creator of the Child Abuse and Neglect Institute offered annually at the National College of Juvenile Law in Reno, Nevada; and as President of the National Council of Juvenile and Family Court Judges and, currently, as Immediate Past President.

Metadata-only record linking to the original dataset. Open original dataset below.
Mutational analysis of Peroxiredoxin IV: exclusion of a positional candidate for multinodular goitre

Background
          Multinodular goitre (MNG) is a common disorder characterised by an enlargement of the thyroid, occurring as a compensatory response to hormonogenesis impairment. The incidence of MNG is dependent on sex (female:male ratio 5:1) and several reports have documented a genetic basis for the disease. Last year we mapped a MNG locus to chromosome Xp22 in a region containing the peroxiredoxin IV (Prx-IV) gene. Since Prx-IV is involved in the removal of H2O2 in thyroid cells, we hypothesize that mutations in Prx-IV gene are involved in pathogenesis of MNG.
        
        
          Methods
          Four individuals (2 affected, 2 unrelated unaffected) were sequenced using automated methods. All individuals were originated from the original three-generation Italian family described in previous studies. A Southern blot analysis using a Prx-IV full-length cDNA as a probe was performed in order to exclude genomic rearrangements and/or intronic mutations. In addition a RT-PCR of PRX-IV was performed in order to investigate expression alterations.
        
        
          Results
          No causative mutations were found. Two adjacent nucleotide substitutions were detected within introns 1 and 4. These changes were also detected in unaffected individuals, suggesting that they were innocuous polymorphisms. No gross genomic rearrangements and/or restriction fragment alterations were observed on Southern analysis. Finally, using RT-PCR from tissue-specific RNA, no differences of PRX-IV expression-levels were detected between affected and unaffected samples.
        
        
          Conclusions
          Based on sequence and genomic analysis, Prx-IV is very unlikely to be the MNG2 gene.
Distribution of serotonergic and dopaminergic nerve fibers in the salivary gland complex of the cockroach

Background
          The cockroach salivary gland consists of secretory acini with peripheral ion-transporting cells and central protein-producing cells, an extensive duct system, and a pair of reservoirs. Salivation is controled by serotonergic and dopaminergic innervation. Serotonin stimulates the secretion of a protein-rich saliva, dopamine causes the production of a saliva without proteins. These findings suggest a model in which serotonin acts on the central cells and possibly other cell types, and dopamine acts selectively on the ion-transporting cells. To examine this model, we have analyzed the spatial relationship of dopaminergic and serotonergic nerve fibers to the various cell types.
        
        
          Results
          The acinar tissue is entangled in a meshwork of serotonergic and dopaminergic varicose fibers. Dopaminergic fibers reside only at the surface of the acini next to the peripheral cells. Serotonergic fibers invade the acini and form a dense network between central cells. Salivary duct segments close to the acini are locally associated with dopaminergic and serotonergic fibers, whereas duct segments further downstream have only dopaminergic fibers on their surface and within the epithelium. In addition, the reservoirs have both a dopaminergic and a serotonergic innervation.
        
        
          Conclusion
          Our results suggest that dopamine is released on the acinar surface, close to peripheral cells, and along the entire duct system. Serotonin is probably released close to peripheral and central cells, and at initial segments of the duct system. Moreover, the presence of serotonergic and dopaminergic fiber terminals on the reservoir indicates that the functions of this structure are also regulated by dopamine and serotonin.
Decay rate of gas-phase peracetic acid in a polyvinyl fluoride sample bag

In this study the temperature dependent decay rate of gas-phase peracetic acid (PAA) concentrations in polyvinyl fluoride (PVF) sample bags was measured. Headspace from a PAA solution was used to dynamically generate atmospheres of gas-phase PAA which were transferred to PVF bags. The concentration of gas-phase PAA in PVF bags, in a temperature-controlled environment, was measured versus time using both selected ion flow-tube mass spectrometry (SIFT-MS) and impinger based colorimetric measurements. A review of PAA decomposition reactions, kinetics, and results of SIFT-MS measure of PAA and acetic acid are discussed. Gas-phase PAA concentrations in the PVF bags exhibited exponential decay consistent with first-order kinetics. The temperature dependent decay rate of gas-phase PAA concentration in PVF sample bags had half-lives that ranged from 19 h (at 30°C) to 45 h (at 10°C).  From the Arrhenius equation, an activation energy of 34.2±1.1 kJ·mol-1 (8.2±0.3 kcal·mol-1) was calculated from the temperature dependence of the decay constant. In this work, the half-lives of gas-phase PAA concentrations measured in PVF were considerably longer than other studies of PAA in containers.
2010 CMHS Uniform Reporting System (URS) Output Tables for Tennessee

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Behavioral Health Barometer: Arizona, 2013

This is a behavioral health report for the state of Arizona.  It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use,  and substance use treatment,  for the years 2008 to 2012.
Compound 526169: Dimethyl 3-cyano-phenyl phosphate

Chemical compound data from PubChem database. IUPAC Name: (3-cyanophenyl) dimethyl phosphate. Molecular Formula: C9H10NO4P. Molecular Weight: 227.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530167: Djenkolic acid, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 3-[[3-oxo-2-(trimethylsilylamino)-3-trimethylsilyloxypropyl]sulfanylmethylsulfanyl]-2-(trimethylsilylamino)propanoate. Molecular Formula: C19H46N2O4S2Si4. Molecular Weight: 543.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
California (CA)

This report presents California\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for California for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Arterial indications for the low molecular weight heparins

Antithrombotic treatment is of proven importance in patients with acute coronary syndromes. There is now accumulating evidence from several clinical trials in patients with unstable angina pectoris that the low molecular weight heparins (LMWHs) are at least as effective as unfractionated heparin. The LMWHs are easier to use, with the potential to facilitate long-term outpatient treatment. The results of the trials have actually failed to show any clear advantage, however, of the LMWHs over the standard antiplatelet treatment, despite the evidence of a sustained hypercoagulability. Potentially, the use of higher doses of LMWHs could improve the outcomes, but this is as yet unproven and could be associated with unacceptably increased risk of bleeding. During the acute phase of a stroke, aspirin is the first choice of antithrombotic drug because it reduces the risk of recurrent stroke. LMWH cannot be recommended as an antithrombotic agent for the acute treatment of stroke. Prophylactic use of low dose LMWH for the prevention of venous thromboembolism should be considered in every patient with a stroke.
Compound 527535: 2,5-Dimethyl-1-(3-methylbutan-2-yl)pyrrole

Chemical compound data from PubChem database. IUPAC Name: 2,5-dimethyl-1-(3-methylbutan-2-yl)pyrrole. Molecular Formula: C11H19N. Molecular Weight: 165.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529945: 2-[(1-Methyl-2-oxopropy1)-dithio]-3-pentanone

Chemical compound data from PubChem database. IUPAC Name: 2-(3-oxobutan-2-yldisulfanyl)pentan-3-one. Molecular Formula: C9H16O2S2. Molecular Weight: 220.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Native Asset Building Initiative - Assets for Independence Partnership

The Native American Asset-Building Initiative is a partnership between the Administration for Native Americans (ANA) and Office of Community Services (OCS). The Initiative focuses on building the capacity of tribes and Native organizations to effectively plan projects and develop competitive applications for funding under the Office of Community Services’ Assets for Independence (AFI) program. Funding for NABI was discontinued in FY16, but there are still several active awards.

OCS and ANA accepted applications to establish and administer asset building projects with a focus on AFI projects. Grantees provide an array of supports and services to enable low income individuals and families to become economically self-sufficient for the long-term. You can read the FOA.

The AFI program supported innovative asset-building projects that feature Individual Development Accounts (IDAs), financial education, and related services that enable low-income people to improve their economic status and become economically self-sufficient.

What is an IDA?
			IDAs are matched savings accounts that enable low-income and low-wealth individuals to save for a specified goal within a defined time frame.

IDA savings placed in an AFI account can be used to build assets in three areas:

For more information about the AFI program, please visit their website. Note that no funds were appropriated for the Assets for Independence (AFI) program for federal fiscal year 2017. Therefore, ACF will not be making new grant awards for the AFI program.

AFI grants awarded in FY 2016 and before are not affected by the FY 2017 appropriation, as the total award amount was obligated for those grants at the time that they were made. Organizations operating AFI projects with existing grants are responsible for continuing to operate those projects for the funded project period indicated on the notice of grant award.

Check out our Native Asset Building Initiative Resources for more training and other information.

Metadata-only record linking to the original dataset. Open original dataset below.
Specificity of DNA triple helix formation analyzed by a FRET assay

Background
          A third DNA strand can bind into the major groove of a homopurine duplex DNA to form a DNA triple helix. Sequence specific triplex formation can be applied for gene targeting, gene silencing and mutagenesis.
        
        
          Results
          We have analyzed triplex formation of two polypurine triplex forming oligodeoxynucleotides (TFOs) using fluorescence resonance energy transfer (FRET). Under our conditions, the TFOs bind to their cognate double strand DNAs with binding constants of 2.6 × 105 and 2.3 × 106 M-1. Our data confirm that the polypurine TFO binds in an antiparallel orientation with respect to the polypurine DNA strand and that triplex formation requires Mg2+ions whereas it is inhibited by K+ions. The rate of formation of triple helices is slow with bimolecular rate constants of 5.6 × 104 and 8.1 × 104 min-1 M-1. Triplex dissociation was not detectable over at least 30 hours. Triplex formation is sequence specific; alteration of a single base pair within the 13 base pairs long TFOs prevents detectable triplex formation.
        
        
          Conclusion
          We have applied a FRET assay to investigate the specificity of DNA triple helix formation. This assay is homogeneous, continuous and specific, because the appearance of the FRET signal is directly correlated to triplex formation. We show that polypurine TFOs bind highly specifically to polypurine stretches in double stranded DNA. This is a prerequisite for biotechnical applications of triple helices to mediate sequence specific recognition of DNA.
Patent AT-E400101-T1: [Translated] IMPROVED MULTI-FRAME PROCESSING FOR TANDEM JOINT TRACKS WITH TRANSMISSION PROTECTION METHOD

According to the invention a synchronous hierarchic network system and a method of transmitting data are disclosed using at least a path segment between a first network element (A) and at least a second network element (F) on which a tandem connection monitoring (TC) method is established for monitoring information over said path segment, and means for suppressing the insertion of all ones caused by the out of multiframe state subsequent to an interruption, distortion or switching operation of the signal transmission path for a predefined time interval.  <IMAGE>
Alprazolam

Alprazolam is a prescription benzodiazepine medication used to treat anxiety and panic disorders. It comes as extended-release oral tablets in strengths of 0.5 mg, 1 mg, 2 mg, and 3 mg, manufactured by Aurobindo Pharma Limited. It is classified as a Schedule CIV controlled substance due to its potential for abuse. This information was generated using AI and is provided for informational and research purposes only.
Compound 529499: 3-Methyl-2-butenoic acid, 2-pentyl ester

Chemical compound data from PubChem database. IUPAC Name: pentan-2-yl 3-methylbut-2-enoate. Molecular Formula: C10H18O2. Molecular Weight: 170.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528029: 1-Phenylethyl pentafluorobenzoate

Chemical compound data from PubChem database. IUPAC Name: 1-phenylethyl 2,3,4,5,6-pentafluorobenzoate. Molecular Formula: C15H9F5O2. Molecular Weight: 316.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review

Background
          Acute hematogenous osteomyelitis (AHO) occurs primarily in children and is believed to evolve from bacteremia followed by localization of infection to the metaphysis of bones. Currently, there is no consensus on the route and duration of antimicrobial therapy to treat AHO.
        
        
          Methods
          We conducted a systematic review of a short versus long course of treatment for AHO due primarily to Staphylococcus aureus in children aged 3 months to 16 years. We searched Medline, Embase and the Cochrane trials registry for controlled trials. Clinical cure rate at 6 months was the primary outcome variable, and groups receiving less than 7 days of intravenous therapy were compared with groups receiving one week or longer of intravenous antimicrobials.
        
        
          Results
          12 eligible prospective studies, one of which was randomized, were identified. The overall cure rate at 6 months for the short course of intravenous therapy was 95.2% (95% CI = 90.4, 97.7) compared to 98.8% (95% CI = 93.6, 99.8) for the longer course of therapy. There was no significant difference in the duration of oral therapy between the two groups.
        
        
          Conclusions
          Given the potential increased morbidity and cost associated with longer courses of intravenous therapy, this finding should be confirmed through a randomized controlled equivalence trial.
Compound 525182: Propylene glycol, monoallyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 1-prop-2-enoxypropan-2-yl acetate. Molecular Formula: C8H14O3. Molecular Weight: 158.19. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Iowa (IA)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Iowa for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.