AndreaBozzo/ceres-open-data-index huggingface dataset:
Noncoding RNA gene detection using comparative sequence analysis

Background
          Noncoding RNA genes produce transcripts that exert their function without ever producing proteins. Noncoding RNA gene sequences do not have strong statistical signals, unlike protein coding genes. A reliable general purpose computational genefinder for noncoding RNA genes has been elusive.
        
        
          Results
          We describe a comparative sequence analysis algorithm for detecting novel structural RNA genes. The key idea is to test the pattern of substitutions observed in a pairwise alignment of two homologous sequences. A conserved coding region tends to show a pattern of synonymous substitutions, whereas a conserved structural RNA tends to show a pattern of compensatory mutations consistent with some base-paired secondary structure. We formalize this intuition using three probabilistic "pair-grammars": a pair stochastic context free grammar modeling alignments constrained by structural RNA evolution, a pair hidden Markov model modeling alignments constrained by coding sequence evolution, and a pair hidden Markov model modeling a null hypothesis of position-independent evolution. Given an input pairwise sequence alignment (e.g. from a BLASTN comparison of two related genomes) we classify the alignment into the coding, RNA, or null class according to the posterior probability of each class.
        
        
          Conclusions
          We have implemented this approach as a program, QRNA, which we consider to be a prototype structural noncoding RNA genefinder. Tests suggest that this approach detects noncoding RNA genes with a fair degree of reliability.
High incidence of Epstein-Barr virus, cytomegalovirus and human herpesvirus 6 infections in children with cancer

Background
          A prospective single-center study was performed to study infection with lymphotropic herpesviruses (LH) Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human herpesvirus 6 (HHV-6) in children with cancer.
        
        
          Methods
          The group of 186 children was examined for the presence of LH before, during and 2 months after the end of anticancer treatment. Serology of EBV and CMV was monitored in all children, serology of HHV-6 and DNA analysis of all three LH was monitored in 70 children.
        
        
          Results
          At the time of cancer diagnosis (pre-treatment), there was no difference between cancer patients and age-matched healthy controls in overall IgG seropositivity for EBV (68.8% vs. 72.0%; p = 0.47) and CMV (37.6% vs. 41.7%; p = 0.36). During anticancer therapy, primary or reactivated EBV and CMV infection was present in 65 (34.9%) and 66 (35.4%) of 186 patients, respectively, leading to increased overall post-treatment IgG seropositivity that was significantly different from controls for EBV (86.6% vs. 72.0%; p = 0.0004) and CMV (67.7% vs. 41.7%; p < 0.0001). Overall pre-treatment IgG seropositivity for HHV-6 was significantly lower in patients than in controls (80.6% vs. 91.3%; p = 0.0231) which may be in agreement with Greaves hypothesis of protective effect of common infections in infancy to cancer development. Primary or reactivated HHV-6 infection was present in 23 (32.9%) of 70 patients during anticancer therapy leading to post-treatment IgG seropositivity that was not significantly different from controls (94.3% vs. 91.3%; p = 0.58). The LH infection occurred independently from leukodepleted blood transfusions given. Combination of serology and DNA analysis in detection of symptomatic EBV or CMV infection was superior to serology alone.
        
        
          Conclusion
          EBV, CMV and HHV-6 infections are frequently present during therapy of pediatric malignancy.
Patent AT-E400063-T1: [Translated] BIPOLAR TRANSISTOR AND PRODUCTION METHOD THEREOF

The invention relates to a semiconductor device (10) with a semiconductor body (12) comprising a bipolar transistor with an emitter region (1), a base region (2) and a collector region (3) of, respectively, a first conductivity type, a second conductivity type, opposite to the first conductivity type, and the first conductivity type, wherein, viewed in projection, the emitter region (1) is positioned above or below the base region (2), and the collector region (3) laterally borders the base region (2). According to the invention, the base region (2) comprises a highly doped subregion (2A) the doping concentration of which has a delta-shaped profile in the thickness direction, and said highly doped sub-region (2A) extends laterally as far as the collector region (3). Such a lateral bipolar transistor has excellent high-frequency properties and a relatively high breakdown voltage between the base and collector regions (2, 3), implying that the device is suitable for high power applications. The doping concentration lies preferably between about 1019 and about 1020 at/cm3, and the thickness of the sub-region (2A) lies between 1 and 15 nm and preferably between 1 and 10 nm. The invention also comprises a method of manufacturing such a device (10).
Compound 525800: N-(4-Methoxyphenyl)-N'-(4-chlorophenyl)formamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-chlorophenyl)-N-(4-methoxyphenyl)methanimidamide. Molecular Formula: C14H13ClN2O. Molecular Weight: 260.72. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527765: 2,2-Dichloroethyl octanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl octanoate. Molecular Formula: C10H18Cl2O2. Molecular Weight: 241.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399563-T1: [Translated] EXTRACELLULAR MATRIX CONTAINING GDF-5 FOR INDUCING OR ENHANCEMENT OF CHONDROGENESIS

A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hyaluronate and further containing GDF-5.
The relationship between FV Leiden and pulmonary embolism

Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be important in reducing mortality. It has previously been thought that deep vein thrombosis and PE are a single disease entity and would, therefore, have the same risk factors. This view is changing, however, with the realization that the prevalence of FV Leiden, a recognized genetic risk factor for deep vein thrombosis, may be a 'milder' genetic risk factor for PE. These observations suggest that PE is not only associated with a different set of risk factors, but may be reflective of a different clot structure.
National Artesunate for Severe Malaria Program Follow-On Antimalarial Dosing Data- April to December 2019

This dataset includes deidentified data on patients receiving artesunate through the National Artesunate for Severe Malaria Program from April- December 2019. 

This dataset contains the data from the case report form only.
Please see the links below for the other datasets and the attached document 'Guide to NASMP Datasets':
Data from Case Report Form- https://data.cdc.gov/Global-Health/National-Artesunate-for-Severe-Malaria-Program-Cas/igaz-icki
Data on Artesunate Dosing- https://data.cdc.gov/dataset/National-Artesunate-for-Severe-Malaria-Program-Art/qan4-gt4k
Data on Microscopy (Parasitemia values)- https://data.cdc.gov/Global-Health/National-Artesunate-for-Severe-Malaria-Program-Mic/v2k9-ctv4

All data can be easily linked using the ParticipantID field, a unique ID number assigned to each participant.
Patients Who Are Privately Insured Receive Limited Follow-up Services After Opioid-Related Hospitalizations

There has been a significant increase in hospitalizations for opioid misuse in recent years. Using 2010-2014 MarketScan commercial data, this report finds that 40 percent of patients do not receive any follow-up services within 30 days after an opioid-related hospitalization. Only 11 percent of patients received the recommended combination of both medication and a therapeutic service.
2014 CMHS Uniform Reporting System (URS) Table for Idaho

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Idaho. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Patent AT-E401095-T1: [Translated] AGENTS FOR MAINTAINING AND/OR CORRECTING BLOOD GLUCOSE CONCENTRATION

The invention relates to preparations that are useful in maintaining mammalian blood glucose concentrations. These preparations contain insulin, and a polymeric matrix. The polymeric matrix has a core of biodegradable, hydrophobic polymer, and an outer shell of a biodegradable, hydrophobic polymer. Alternately, the formulations contain insulin, a polymeric matrix, and a histone.
CDC STATE System Tobacco Legislation - Smokefree Campus

1995-2024. Centers for Disease Control and Prevention (CDC).  State Tobacco Activities Tracking and Evaluation (STATE) System. Legislation – Smokefree Campuses. The STATE System houses current and historical state-level legislative data on tobacco use prevention and control policies. Data are reported on a quarterly basis. Data include state smokefree indoor air policies in areas such as: Smokefree campuses for private and public colleges and schools (K-12).
Ropinirole

Ropinirole is a prescription medication that acts as a dopamine agonist to help manage symptoms of Parkinson's disease, such as tremors, stiffness, and slow movement, and restless legs syndrome. It comes as oral tablets in strengths from 0.25 mg to 5 mg, manufactured by Glenmark Pharmaceuticals Inc., USA. This information was generated using AI and is provided for informational and research purposes only.
Patent AT-E400248-T1: [Translated] PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING PHOSPHOLIPIDE COMPLEXES OF EXTRACTS FROM VITIS VINIFERA AND CENTELLA ASIATICA

Pharmaceutical and cosmetic compositions for the prevention of skin aging, containing phospholipid complexes of extracts of Vitis vinifera, and phospholipid complexes of standardized extract from Centella asiatica.
Compound 529958: Bis(1-methyl-2-oxopropyl) disulfide

Chemical compound data from PubChem database. IUPAC Name: 3-(3-oxobutan-2-yldisulfanyl)butan-2-one. Molecular Formula: C8H14O2S2. Molecular Weight: 206.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400017-T1: [Translated] INPUT DEVICE FOR A PORTABLE ELECTRONIC DEVICE AND METHOD FOR INPUT USING THE SAME

An improved input apparatus and method of enabling input improve handheld electronic devices having a housing and a processor apparatus disposed on the housing. The processor apparatus comprises a processor and a memory. The input apparatus includes an input assembly with an input device for providing input to the processor, a plurality of input members, and at least a first actuating element movable between a first position and a second position. In the second position, the actuating element actuates the input device. Each input member of the portion of input members is movable among an unactuated position and an actuated position. Each of a plurality of input members of the portion of input members, in the actuated position, is engageable with the actuating element to move it toward the second position. The input apparatus enables close arrangement of the input members to provide, for example, a compact keyboard layout.
Compound 526724: Triethylene glycol, decyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-(2-decoxyethoxy)ethoxy]ethyl acetate. Molecular Formula: C18H36O5. Molecular Weight: 332.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Updates on AFCARS Technical Bulletins and the Penalty Process Office Hours

The Children's Bureau Data Analytics and Reporting Team held an office hours session on June 24, 2024, from 3:00pm to 4:00pm ET. For this office hour, the Children's Bureau shared updates on revised technical bulletins and revisions to the penalty process.  This was also an opportunity for states, tribes, and territories to ask questions.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525206: Chloromethyl 4-chlorohexanoate

Chemical compound data from PubChem database. IUPAC Name: chloromethyl 4-chlorohexanoate. Molecular Formula: C7H12Cl2O2. Molecular Weight: 199.07. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400347-T1: [Translated] MICROPOROUS PAPER FILTER FOR PARTICLES

A microporous paper filter (10) for particulates emitted together with the exhaust gases of internal combustion engines, made in the form of a folded up sheet to form a "Greek key" i.e. having several filtering layers (13) placed substantially parallel, connected by means of folds (14), the layers (13) being separated and maintained equidistant through the interposition of spacers (20) each comprising at least one corrugated paper sheet (21, 22) or pleated paper (23). <IMAGE>
COVID-19 Wastewater Detection - Historical

As described in https://data.cityofchicago.org/stories/s/sihu-d8va, the function of this dataset was replaced by https://data.cityofchicago.org/d/4tzt-ir6h. This dataset is historical-only.

Concentrations of the SARS-CoV-2 virus (the COVID-19 virus) gene in the Chicago sewer system, as measured at eight sewershed sites. These sites represent catchment areas that describe wastewater from 319,700 Chicagoans as of January 2023.

Because SARS-CoV-2 is shed in human feces, this method can be used to estimate changes in COVID-19 at different times and locations across Chicago. While the data in this dataset do not indicate how many people were infected with SARS-CoV-2, differences in the the normalized_n1 indicate whether the proportion of individuals at the site who are shedding that virus has changed.
Patent AT-E401755-T1: [Translated] RESIDENCY IN A TELECOMMUNICATIONS SYSTEM

The invention relates to a method for supporting location determination of a mobile station, in which method location data are stored in and deleted from a memory, each location data item describing the location of the mobile station measured at a given measuring moment. Furthermore, in the method, a distance parameter and/or a target level corresponding to the distance parameter is determined at least for some of the stored location data; and deletion of the location data is at least partly based on the distance parameter and target level.
Patent AT-E40051-T1: [Translated] FLUE GAS DESULPHURIZATION PROCESS.

In the desulphurizing of SO2- and hydrogen halide-containing flue gases by catalytically oxidizing the sulphur dioxide on moist active carbon at a temperature of from 45 DEG  to 70 DEG  C. with the formation of 3 to 20% dilute sulphuric acid, the improvement which comprises contacting the dilute sulphuric acid with the hot flue gases to be desulphurized so as to evaporate water resulting sulphuric acid of a concentration of from 60 to 85%, and removing by evaporation the hydrogen chloride and hydrogen fluoride dissolved in the dilute sulphuric acid. Advantageously evaporation is carried out in two scrubbing stages, the hydrogen chloride and hydrogen fluoride being removed, by vacuum evaporation or by stripping with air or flue gas, from a mixture of the dilute sulphuric acid from the second scrubbing stage with the concentrated sulphuric acid from the first scrubbing stage, the mixture having the H2SO4 concentration of from 40 to 70%.
Medicare Part D Prescribers - by Geography and Drug

The Medicare Part D Prescribers by Geography and Drug dataset contains information on prescription drugs prescribed by individual physicians and other health care providers and paid for under the Medicare Part D Prescription Drug Program. For each drug, the dataset includes the total number of prescriptions that were dispensed, which include original prescriptions and any refills, and the total drug cost. The total drug cost includes the ingredient cost of the medication, dispensing fees, sales tax, and any applicable administration fees and is based on the amount paid by the Part D plan, Medicare beneficiary, government subsidies, and any other third-party payers.
Compound 528909: Mandelic acid, 2-hydroxy, DCTFA-acetate

Chemical compound data from PubChem database. IUPAC Name: [2-[2,2-bis[chloro(difluoro)methyl]-5-oxo-1,3-dioxolan-4-yl]phenyl] acetate. Molecular Formula: C13H8Cl2F4O5. Molecular Weight: 391.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529429: 2(1H)-Naphthalenone, 6-methoxy

Chemical compound data from PubChem database. IUPAC Name: 6-methoxy-1H-naphthalen-2-one. Molecular Formula: C11H10O2. Molecular Weight: 174.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Identification of four families of yCCR4- and Mg

Background
          The yeast yCCR4 factor belongs to the CCR4-NOT transcriptional regulatory complex, in which it interacts, through its leucine-rich repeat (LRR) motif with yPOP2. Recently, yCCR4 was shown to be a component of the major cytoplasmic mRNA deadenylase complex, and to contain a fold related to the Mg2+-dependent endonuclease core.
        
        
          Results
          Here, we report the identification of nineteen yCCR4-related proteins in eukaryotes (including yeast, plants and animals), which all contain the yCCR4 endonuclease-like fold, with highly conserved CCR4-specific residues. Phylogenetic and genomic analyses show that they form four distinct families, one of which contains the yCCR4 orthologs. The orthologs in animals possess a leucine-rich repeat domain. We show, using two-hybrid and far-Western assays, that the human member binds to the human yPOP2 homologs, i.e. hCAF1 and hPOP2, in a LRR-dependent manner.
        
        
          Conclusions
          We have identified the mammalian orthologs of yCCR4 and have shown that the human member binds to the human yPOP2 homologs, thus strongly suggesting conservation of the CCR4-NOT complex from yeast to human. All members of the four identified yCCR4-related protein families show stricking conservation of the endonuclease-like catalytic motifs of the yCCR4 C-terminal domain and therefore constitute a new family of potential deadenylases in mammals.
U.S. State and Territorial Stay-At-Home Orders: March 15, 2020 – August 15, 2021 by County by Day

State and territorial executive orders, administrative orders, resolutions, and proclamations are collected from government websites and cataloged and coded using Microsoft Excel by one coder with one or more additional coders conducting quality assurance.

Data were collected to determine when individuals in states and territories were subject to executive orders, administrative orders, resolutions, and proclamations for COVID-19 that require or recommend people stay in their homes. Data consists exclusively of state and territorial orders, many of which apply to specific counties within their respective state or territory; therefore, data is broken down to the county level.

These data are derived from the publicly available state and territorial executive orders, administrative orders, resolutions, and proclamations (“orders”) for COVID-19 that expressly require or recommend individuals stay at home found by the CDC, COVID-19 Community Intervention and At-Risk Task Force, Monitoring and Evaluation Team & CDC, Center for State, Tribal, Local, and Territorial Support, Public Health Law Program from March 15, 2020 through August 15, 2021. These data will be updated as new orders are collected. Any orders not available through publicly accessible websites are not included in these data. Only official copies of the documents or, where official copies were unavailable, official press releases from government websites describing requirements were coded; news media reports on restrictions were excluded. Recommendations not included in an order are not included in these data. These data do not include mandatory business closures, curfews, or limitations on public or private gatherings. These data do not necessarily represent an official position of the Centers for Disease Control and Prevention.
Patent AT-E400592-T1: [Translated] EMULGATOR-FREE AQUEOUS EMULSION POLYMERIZATION PROCESS FOR THE PRODUCTION OF FLUORPOLYMERS

Emulsifier free fluoropolymer manufacturing method in which (a) a chain transfer agent, or a mixture of chain transfer agents are used wherein the chain transfer agents do not yield more than 0.4 weight % relative to the monomer feed of water soluble fluorinated compounds, or (b) a chain transfer agent or a mixture of chain transfer agents selected from alkanes, dialkyl ethers, hydrofluoroethers and/or hydrofluorocarbons.
Patent AT-E399642-T1: [Translated] FLAT PLATE PRECURSOR

The invention provides a planographic printing plate precursor including a photosensitive layer containing an infrared absorbent, a polymerization initiator, a polymerizable compound, and a binder polymer, and a protective layer containing an inorganic layered compound, formed in this order on a surface of a hydrophilic aluminum support, wherein at least one of the photosensitive layer and the protective layer contains a phosphonium compound.
Compound 529348: Pyridine, 2-methyl-4-(1-methylethyl)

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-4-propan-2-ylpyridine. Molecular Formula: C9H13N. Molecular Weight: 135.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Treatment Episode Data Set (TEDS): 1992-1995, National Admissions to Substance Abuse Treatment Services

This report presents data from the Treatment Episode Data Set (TEDS) for 1995, and trend data for 1992 to 1995. The report provides information on the demographic and substance abuse characteristics of people aged 12 and older admitted to treatment for abuse of alcohol and/or drugs in facilities that report to individual state administrative data systems.