AndreaBozzo/ceres-open-data-index huggingface dataset:
Impact of UVA exposure on psychological parameters and circulating serotonin and melatonin

Background
          People tend to feel better after exposure to ultraviolet (UV) radiation. This study was performed to investigate the impact of UVA exposure on psychological and neuroendocrine parameters.
        
        
          Methods
          Fifty-three volunteers were separated into 42 individuals who had UVA exposure and 11 individuals who had no UVA exposure. The UVA-exposed volunteers had irradiation sessions six times in a three-week period. All volunteers completed two questionnaires at baseline (T1) and at the end of the study (T3). For the determination of serotonin and melatonin serum levels of all volunteers blood samples were collected at baseline (T1), after the first UVA exposure (T2), and at the end of the study after the sixth exposure (T3).
        
        
          Results
          UVA-exposed volunteers felt significantly more balanced, less nervous, more strengthened, and more satisfied with their appearance at T3. By contrast, the controls did not show significant changes of psychological parameters. In comparison to T1 and T3, serum serotonin was significantly higher and the serum melatonin was significantly lower for the volunteers exposed to UVA at T2. Both, for exposed and non-exposed volunteers serotonin and melatonin levels did not significantly differ at T1 and T3.
        
        
          Conclusions
          It remains obscure, whether the exposure to UVA or other components of the treatment were responsible for the psychological benefits observed. The changes of circulating neuroendocrine mediators found after UVA exposure at T2 may be due to an UVA-induced effect via a cutaneous pathway. Nevertheless, the positive psychological effects observed in our study cannot be attributed to circulating serotonin or melatonin.
CDC PRAMStat Data for 2002

2002.  Centers for Disease Control and Prevention (CDC). PRAMS, the Pregnancy Risk Assessment Monitoring System, is a surveillance system collecting state-specific, population-based data on maternal attitudes and experiences before, during, and shortly after pregnancy. It is a collaborative project of the Centers for Disease Control and Prevention (CDC) and state health departments. PRAMS provides data for state health officials to use to improve the health of mothers and infants. PRAMS topics include abuse, alcohol use, contraception, breastfeeding, mental health, morbidity, obesity, preconception health, pregnancy history, prenatal-care, sleep behavior, smoke exposure, stress, tobacco use, WIC, Medicaid, infant health, and unintended pregnancy. Data will be updated annually as it becomes available.
Compound 526491: 1,1,1-Trifluorooctane

Chemical compound data from PubChem database. IUPAC Name: 1,1,1-trifluorooctane. Molecular Formula: C8H15F3. Molecular Weight: 168.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Percutaneous tracheostomy: comparison of Ciaglia and Griggs		  techniques

Endoscopic percutaneous dilatational tracheostomy is at least as			 safe as standard open tracheostomy in the operating room (OR). Recently, a			 single dilator was introduced to accomplish dilatation of the tracheal aperture			 in one step, thus obviating the need for multiple graduated dilators.			 Experience with endoscopic percutaneous tracheostomy (PCT) using the single			 dilator in 40 patients to date supports the premise that the procedure is safe,			 rapid, and technically simple. In the study by Añon et al, two			 very different techniques, are compared: the Ciaglia percutaneous dilatational			 tracheostomy technique using multiple dilators and the Griggs percutaneous			 technique using guidewire-dilating forceps. Although relative complication			 rates for the two techniques are not significantly different, both procedures			 are performed in a 'blind' fashion, without the benefit of a			 bronchoscope. The reported incidence of serious complications in this study is			 high, and almost certainly avoidable with the addition of direct bronchoscopic			 visualization. Operative time is reported to be shorter with the Griggs			 technique, but this finding is unlikely to hold true for the single dilator			 technique, which reduces procedure time to less than 15 min. This author's			 experience with bedside endoscopic PCT using the single dilator indicates that			 it is a safe, rapid and cost-effective procedure with a low complication			 rate.
Dental Utilization Measures and Sealant Data by Ethnicity and Age Calendar Year 2013 to 2022

This dataset shows use of Medi-Cal dental benefits by Medi-Cal members displayed by ethnicity, age groups, and calendar year (for 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, and 2022). This information consists of members receiving dental services in the following categories: Annual Dental Visit, Exams/Oral Health Evaluations, Use of Diagnostic Services, Use of Dental Treatment Services, Use of Preventive Services, Use of Restorative Services, Treatment/Prevention for Caries, and Use of Sealants. The Medi-Cal members were continuously enrolled in either Dental Managed Care or the Dental Fee-for-Service delivery system for at least 3 months during each measure year.
Surfactant gene polymorphisms and interstitial lung diseases

Pulmonary surfactant is a complex mixture of phospholipids and proteins, which is present in the alveolar lining fluid and is essential for normal lung function. Alterations in surfactant composition have been reported in several interstitial lung diseases (ILDs). Furthermore, a mutation in the surfactant protein C gene that results in complete absence of the protein has been shown to be associated with familial ILD. The role of surfactant in lung disease is therefore drawing increasing attention following the elucidation of the genetic basis underlying its surface expression and the proof of surfactant abnormalities in ILD.
Compound 526167: Dimethyl 3-bromophenyl phosphate

Chemical compound data from PubChem database. IUPAC Name: (3-bromophenyl) dimethyl phosphate. Molecular Formula: C8H10BrO4P. Molecular Weight: 281.04. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528883: Tyr, N-acetyl-PFP

Chemical compound data from PubChem database. IUPAC Name: [4-[2-[acetyl(2,2,3,3,3-pentafluoropropanoyl)amino]ethyl]phenyl] 2,2,3,3,3-pentafluoropropanoate. Molecular Formula: C16H11F10NO4. Molecular Weight: 471.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Message to complementary and alternative medicine: evidence is a better friend than power

Background
          Evidence-based medicine (EBM) is being embraced by an increasing number of practitioners and advocates of complementary and alternative medicine (CAM). A significant constituency within CAM, however, appears to have substantive doubts about EBM and some are expressly hostile.
        
        
          Discussion
          Many of the arguments raised against EBM within the CAM community are based on a caricature radically at odds with established, accepted and published principles of EBM practice. Contrary to what has sometimes been argued, EBM is not cookbook medicine that ignores individual needs. Neither does EBM mandate that only proven therapies should be used. Before EBM, decisions on health care tended to be based on tradition, power and influence. Such modes usually act to the disadvantage of marginal groups.
        
        
          Conclusion
          By placing CAM on an equal footing with conventional medicine - what matters for both is evidence of effectiveness - EBM provides an opportunity for CAM to find an appropriate and just place in health care.
Compound 528032: Heptyl 3,5-dinitrobenzoate

Chemical compound data from PubChem database. IUPAC Name: heptyl 3,5-dinitrobenzoate. Molecular Formula: C14H18N2O6. Molecular Weight: 310.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401425-T1: [Translated] USE OF A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CODING AREA OF THE PORK LEPTIN RECEPTOR GENE TO IMPROVE PORK PRODUCTION

Chemical patent from PubChem database. Patent Number: AT-E401425-T1. Title: Novel Chemical Entity. Filing Date: 2011-01-02. Inventors: Smith, John A., Johnson, Mary B.. Abstract: The invention relates to a novel chemical entity with unique structural features and biological properties, suitable for development as a therapeutic ... IPC Classifications: C12N, C12P, A61K. This patent covers 46 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Handheld computers in critical care

Background
          Computing technology has the potential to improve health care management but is often underutilized. Handheld computers are versatile and relatively inexpensive, bringing the benefits of computers to the bedside. We evaluated the role of this technology for managing patient data and accessing medical reference information, in an academic intensive-care unit (ICU).
        
        
          Methods
          Palm III series handheld devices were given to the ICU team, each installed with medical reference information, schedules, and contact numbers. Users underwent a 1-hour training session introducing the hardware and software. Various patient data management applications were assessed during the study period. Qualitative assessment of the benefits, drawbacks, and suggestions was performed by an independent company, using focus groups. An objective comparison between a paper and electronic handheld textbook was achieved using clinical scenario tests.
        
        
          Results
          During the 6-month study period, the 20 physicians and 6 paramedical staff who used the handheld devices found them convenient and functional but suggested more comprehensive training and improved search facilities. Comparison of the handheld computer with the conventional paper text revealed equivalence. Access to computerized patient information improved communication, particularly with regard to long-stay patients, but changes to the software and the process were suggested.
        
        
          Conclusions
          The introduction of this technology was well received despite differences in users' familiarity with the devices. Handheld computers have potential in the ICU, but systems need to be developed specifically for the critical-care environment.
Alteration in expression of the rat mitochondrial ATPase 6 gene during

Background
          Pneumocystis carinii causes pneumonia in immunocompromised patients with a high morbidity and mortality rate, but the interaction between this organism and the host cell is not well understood. The purpose of this research was to study the response of host cells to P. carinii infection on a molecular level.
        
        
          Results
          The technique of mRNA differential display was used to detect genes whose expression may be affected by P. carinii infection. The nucleotide sequence of one differentially displayed DNA fragment was found to be identical to that of the rat mitochondrial ATPase 6 gene, which is a subunit of the F0F1-ATP synthase complex. A four-fold increase in expression of this gene was verified by Northern blot analysis of total RNA extracted from P. carinii-infected rat lung versus that from mock-infected rat lung. Localization of the cells containing ATPase 6 mRNA was accomplished by in situ hybridization. In sections of non-infected rat lung, these cells were found lining the distal parts of the respiratory tree and in apical areas of the alveoli. Histological location of these cells suggested that they were Clara cells and type II pneumocytes. This hypothesis was confirmed by co-localizing the mRNAs for ATPase 6 and surfactant protein B (SP-B) to the same cells by two-color fluorescent in situ hybridization.
        
        
          Conclusions
          The ATPase 6 gene is over expressed during P. carinii infection, and type II pneumocytes and Clara cells are the cell types responsible for this over-expression.
Patent AT-E400911-T1: [Translated] SEGMENTED DIODE LASER SYSTEM

Disclosed is a laser system that comprises a laser source adapted to emit a laser beam, wherein the laser source comprises a plurality of emitters for emitting respective beam contributions to the emitted laser beam; and first and second feedback means adapted to provide optical feedback to respective first and second parts of the emitted laser beam. The first feedback means is adapted to predominantly feed back a respective angular/directional contribution of each of said beam contributions into a corresponding one of the plurality of emitters from which said angular/directional contribution was emitted at a predetermined output angle, to cause each of the plurality of emitters to predominantly emit a beam contribution towards the second feedback means at an angle corresponding to the predetermined output angle.
Compound 525383: 2-(Isopropyldisulfanyl)butane

Chemical compound data from PubChem database. IUPAC Name: 2-(propan-2-yldisulfanyl)butane. Molecular Formula: C7H16S2. Molecular Weight: 164.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400300-T1: [Translated] POLYAMINE-METAL CHELATING CONJUGATES

Many metal chelators have polar or charged functional groups, which render them difficult to transport across a cell membrane. Polyamine-metal chelator conjugates of the invention are compounds comprising a first moiety which is a metal chelator and a second moiety which is a polyamine, where the polyamine moiety includes three or more nitrogen atoms which are capable of being positively charged at physiological pH. A spermine-L1 conjugate has been shown to accumulate in L1210 cells several hundred fold more than the unconjugated L1 chelator.
National Survey of Substance Abuse Treatment Services: State Profiles 2002

The 2002 National Survey of Substance Abuse Treatment Services (N-SSATS) is an annual survey of facilities providing substance abuse treatment. The N-SSATS, conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), is designed to collect data on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse facilities (both public and private) throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.
Compound 526916: (3-Bromoadamantan-1-YL)(phenyl)methanone

Chemical compound data from PubChem database. IUPAC Name: (3-bromo-1-adamantyl)-phenylmethanone. Molecular Formula: C17H19BrO. Molecular Weight: 319.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400298-T1: [Translated] PHARMACEUTICAL COMBINATION PREPARATIONS FOR THE TREATMENT OF DIABETES MELLITUS

Pharmaceutical combinations for treatment and/or prevention of all sorts, periods and complications of diabetes mellitus in mammals, thus including the pre-diabetic diseases and their complications, optionally including furthermore ischaemic heart disease comprising an effective dose of at least one enzymatic nitric oxide (NO) donor active ingredient and optionally comprising an effective dose of at least one antidiabetic active ingredient, and further optionally comprising usual pharmaceutically acceptable carriers and/or other auxiliaries. The combination may consist of more than one pharmaceutical compositions. The effective doses related to the new insulin-sensitizing effect are considerably lower than the usual doses related to the know effect of most active substances dues to metabolic effects that influence insulin sensitivity in healthy and insulin resistant mammals. The usual dose of NO-donors is necessary when the patient has also ischaemic heart disease. Preferred antidiabetics include insulin, a thiazolidinedion, a biguanide derivative, an alpha-glucosidase-inhibitor, and alpha2-adrenergic-antagonist and/or a sulphonamide, preferably a sulphonylurea. Preferred enzymatic NO donors are nitroglycerin, racemic isosorbide monoitrate, and/or its stereoisomers, racemic isosorbide dinitrate and/or its stereoisomers, erythityl tetranitrate, pentaerythritol-tetranitrate, methylpropyl-propanediol-dinitrate, propatyl nitrate, trolnitrate, tenitramine and/or nicorandile. The invention includes methods of treatment and processes to prepare the compositions.
Visible Human Project

The NLM Visible Human Project® has created publicly-available complete, anatomically detailed, three-dimensional representations of a human male body and a human female body. Specifically, the VHP provides a public-domain library of cross-sectional cryosection, CT, and MRI images obtained from one male cadaver and one female cadaver. The Visible Man data set was publicly released in 1994 and the Visible Woman in 1995.

https://www.nlm.nih.gov/research/visible/visible_human.html
Berotralstat hydrochloride

Orladeyo (berotralstat hydrochloride) is a prescription oral capsule medication manufactured by BioCryst Pharmaceuticals Inc. It works as a plasma kallikrein inhibitor to help prevent swelling attacks in people with hereditary angioedema. Available in 110 mg and 150 mg strengths, it's taken once daily. This information was generated using AI and is provided for informational and research purposes only.
Compound 529998: Trimethylsilyl 2-[(trimethylsilyl)amino]-3-(4-[(trimethylsilyl)oxy]phenyl)propanoate

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-(trimethylsilylamino)-3-(4-trimethylsilyloxyphenyl)propanoate. Molecular Formula: C18H35NO3Si3. Molecular Weight: 397.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525903: N,N-Dimethyl-N'-heptyl-pivalamidine

Chemical compound data from PubChem database. IUPAC Name: N'-heptyl-N,N,2,2-tetramethylpropanimidamide. Molecular Formula: C14H30N2. Molecular Weight: 226.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526661: 4-Methyl-3-thiazoline

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-2,5-dihydro-1,3-thiazole. Molecular Formula: C4H7NS. Molecular Weight: 101.17. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Monthly Nirsevimab Receipt and Intent Among Females Aged 18-49 Years Who Have a Baby <8 Months, Are Currently Pregnant, or Are Trying to Get Pregnant, United States

Monthly Nirsevimab Receipt and Intent Among Females Aged 18-49 Years Who Have a Baby <8 Months, Are Currently Pregnant, or Are Trying to Get Pregnant. 

• Using data from the National Immunization Survey-Adult COVID Module (NIS-ACM), monthly estimates of receipt and intent for baby’s receipt of nirsevimab reported by females aged 18-49 years with infants under the age of 8 months, females aged 18-49 years who are currently pregnant, and females aged 18-49 years who are currently trying to get pregnant. 

• The NIS-ACM is an ongoing random-digit-dial cellular telephone survey of households with adults 18 years and older.
Compound 527271: Lavandulyl isovalerate

Chemical compound data from PubChem database. IUPAC Name: (5-methyl-2-prop-1-en-2-ylhex-4-enyl) 3-methylbutanoate. Molecular Formula: C15H26O2. Molecular Weight: 238.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527424: 1,5,8-p-Menthatriene

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-5-prop-1-en-2-ylcyclohexa-1,3-diene. Molecular Formula: C10H14. Molecular Weight: 134.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2015-2016 NSDUH State Estimates of Substance Use and Mental Disorders

State estimates for 15 measures of substance use and mental disorders based on the combined 2015 and 2016 National Surveys on Drug Use and Health (NSDUHs) are provided. The NSDUH is an annual survey of the civilian, noninstutionalized population of the United States aged 12 years or older. State and regional estimates are based on a small area estimation (SAE) methodology in which state-level NSDUH data are combined with county and census block group/tract-level data from the state.
Compound 530274: cis-Isocohumulone, TMS

Chemical compound data from PubChem database. IUPAC Name: 1-[3,4-bis(3-methylbut-2-enyl)-2,3,5-tris(trimethylsilyloxy)cyclopenta-1,4-dien-1-yl]-2-methylpropan-1-one. Molecular Formula: C28H52O4Si3. Molecular Weight: 537.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526933: 2-Furfuryl 2-thienyl disulfide

Chemical compound data from PubChem database. IUPAC Name: 2-[(thiophen-2-yldisulfanyl)methyl]furan. Molecular Formula: C9H8OS3. Molecular Weight: 228.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401773-T1: [Translated] HARVESTING MACHINE, ESPECIALLY FOR LEEK AND THE LIKE

The machine has a storage container (7) including an end wall (23) moving from a lower position to a higher position at the level of two other end walls. A chassis (3) includes a support unit (26) for positioning the container on a cleaned surface. Harvested products (10) are disposed transversally onto the container by a harvesting unit and are made to fall in a transversal position into the container.
CDC BioSense On-Boarding

<p>The Tarrant County Public Health (TCPH) and Biosense collaboration is an effort to visualize TCPH health data collected by Biosense using Google Fusion Table technology and make that visualization publicly available. The data consists of patient visits to hospital emergency departments associated with Tarrant County Public Health (TCPH)  that had the illness Gastro Intestinal, Heat Related, or Upper Respiratory divided by all emergency department visits that occurred for the same time period and in the geographic granularity for which the calculation was made.</p>