AndreaBozzo/ceres-open-data-index huggingface dataset:
Polymorphisms in the

Background
          Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN). Antioxidant enzymes may protect against the rapid onset and progression of DN, by reducing the excess of OFR and peroxide. Mutations and polymorphisms in the genes encoding such enzymes may therefore result in predisposition to DN. We investigated the role of genes encoding two antioxidant enzymes, mitochondrial (Mn-SOD) and extracellular (EC-SOD) superoxide dismutase, in DN pathogenesis in a Russian population. We studied Ala(-9)Val and Ile58Thr polymorphisms of the Mn-SOD gene and Arg213Gly dimorphism of the EC-SOD gene in type 1 diabetic patients with (n = 82) and without DN (n = 84).
        
        
          Results
          We developed and used a new polymerase chain reaction (PCR) assays for rapid detection of polymorphisms. These assays involved the use of mismatch PCR primers to create restriction sites in the amplified product only in presence of the polymorphic base. The PCR product was than digested with BshTI, Eco32I or Eco52I to detect Ala(-9)Val, Ile58Thr or Arg213Gly polymorphic site respectively. The frequencies of the Ala allele (50.6% vs. 68.5%, p < 0.002) and the Ala/Ala genotype (17.1% vs. 39.3%, p < 0.005) of the Mn-SOD gene were significantly lower in DN patients than in diabetic subjects without DN. In contrast, the Val allele (49.4% vs. 31.5%, p < 0.002) and the Val/Val genotype (15.9% vs. 2.4%, p < 0.01) were significantly more frequent in the DN patients than in the control group.
        
        
          Conclusions
          Ala(-9)Val substitution in the Mn-SOD gene was associated with DN in a Russian population
NHSC Jobs Center for Primary Care Medical, Dental and Mental Health Providers

<p>The National Health Service Corps (NHSC) Jobs Center helps doctors and nurses who are interested in working at areas where there is the highest need find out more about opportunities in a particular area or healthcare discipline. The Job Center provides information on the work locations and area. Job opportunities can be searched and identified by a combination of search parameters. The user views the search results on a map and as text and both views provide links to get more detailed information for each returned opportunity.</p>
Systemic toxicity induced by topical application of perfluoroheptanoic acid (PFHpA), perfluorohexanoic acid (PFHxA), and perfluoropentanoic acid (PFPeA) in a murine model

Perfluoroheptaoinc acid (PFHpA), perfluorohexanoic acid (PFHxA), and perfluoropentanoic acid (PFPeA) are synthetic chemicals belonging to the per- and polyfluoroalkyl substances (PFAS) group that includes over 5,000 chemicals.  PFHpA, PFHxA, and PFPeA are short-chain PFAS (C7, C6, C5, respectively) that have been labeled as a safer alternative to the legacy PFAS perfluorooctanoic acid (PFOA) and perfluorooctane sulfate (PFOS) which have been linked to numerous health effects.  This class of chemicals are incorporated into consumer products such as stain resistant carpeting and textiles, nanosprays, medical devices, and fire-fighting foams.  There is a high potential for occupational exposure and in the environment, short-chain PFAS have been detected in a variety of water sources leading to concerns for dermal exposure, however, these studies are lacking.  In previous studies from our lab, PFOA was demonstrated to be absorbed via the skin and immunomodulatory.  Also, the short-chain PFAS, PFBA, was found to have systemic toxic effects on mice with dermal exposure.  In the present study, the systemic toxicity of a 28-day dermal PFHpA, PFHxA, and PFPeA (1.25-5% w/v or v/v, or 31.25-125 mg/kg/dose) exposure was evaluated in a murine model.
Compound 530333: Methyl 4,7,10,13,16,19-docosahexaenoate

Chemical compound data from PubChem database. IUPAC Name: methyl docosa-4,7,10,13,16,19-hexaenoate. Molecular Formula: C23H34O2. Molecular Weight: 342.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2013 CMHS Uniform Reporting System (URS) Tables for Kansas

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Kansas for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
NF-kappaB in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction

The transcription factor NF-κB has been well recognized as a pivotal regulator of inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad involvement of NF-κB in other aspects of RA pathology, including development of T helper 1 responses, activation, abnormal apoptosis and proliferation of RA fibroblast-like synovial cells, and differentiation and activation of bone resorbing activity of osteoclasts. In agreement with this, studies in animal models of RA have demonstrated the high therapeutic efficacy of specific inhibitors of NF-κB pathway, indicating the feasibility of anti-NF-κB therapy for human disease.
California Hospital Performance Ratings for Coronary Artery Bypass Graft (CABG) Surgery

This dataset contains the location of hospitals that performed Coronary Artery Bypass Graft (CABG) surgery in California from 2011 to 2022. It also provides performance ratings for the following risk-adjusted outcome measures related to the CABG surgery: operative mortality for isolated CABG and CABG plus valve, post-operative stroke, and 30-day all cause readmission. The dataset also includes the number of cases and adverse events for each CABG outcome measure. The methodology, including risk models that generated the rates and performance ratings differed among years. Users should exercise caution when comparing trends of rates over time (see metadata for more information).
Patent AT-E399542-T1: [Translated] ALFAVBETA3 AND ALFAVBETA6 INTEGRIN ANTAGONISTS AS ANTIFIBROTIC AGENTS

Chemical patent from PubChem database. Patent Number: AT-E399542-T1. Title: Novel Pharmaceutical Composition. Filing Date: 1999-11-21. Inventors: Smith, John A., Johnson, Mary B.. Abstract: The present invention relates to a novel pharmaceutical composition comprising one or more active pharmaceutical ingredients and pharmaceutically acce... IPC Classifications: C07D, C07F, A61K. This patent covers 17 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Compound 528837: Methyl 2-hydroxy-4-([(E)-(2-hydroxy-1-naphthyl)methylidene]amino)benzoate

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethoxypropyl 13-methyltetradecanoate. Molecular Formula: C20H40O4. Molecular Weight: 344.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Tampa-St. Petersburg-Clearwater, FL

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Tampa-St. Petersburg-Clearwater, FL metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for the Tampa-St. Petersburg-Clearwater metro area, Florida, and the U.S. overall.
Compound 530591: 2-Chloropropionic acid, pentadecyl ester

Chemical compound data from PubChem database. IUPAC Name: pentadecyl 2-chloropropanoate. Molecular Formula: C18H35ClO2. Molecular Weight: 318.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529477: 1,6-Anhydroiditol, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[3,5,6-tris(trimethylsilyloxy)oxepan-4-yl]oxysilane. Molecular Formula: C18H44O5Si4. Molecular Weight: 452.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
SHIP Age-Adjusted Mortality Rate From Heart Disease 2009-2021

This is historical data. The update frequency has been set to "Static Data" and is here for historic value. Updated on 8/14/2024

Age-Adjusted Mortality Rate From Heart Disease - This indicator shows the age-adjusted mortality rate from heart disease (per 100,000 population). Heart disease is the leading cause of death in Maryland accounting for 25% of all deaths. Between 2012-2014, over 30,000 people died of heart disease in Maryland. <a href ="https://health.maryland.gov/pophealth/Documents/SHIP/SHIP%20Lite%20Data%20Details/Age-Adjusted%20Heart%20Disease.pdf" > Link to Data Details </a>
Compound 528583: Benzeneacetic acid, alpha-[(tert-butyldimethylsilyl)oxy]-, tert-butyldimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[tert-butyl(dimethyl)silyl]oxy-2-phenylacetate. Molecular Formula: C20H36O3Si2. Molecular Weight: 380.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Nutrition in the intensive care unit

Nutritional support has become a routine part of the care of the critically ill patient. It is an adjunctive therapy, the main goal of which is to attenuate the development of malnutrition, yet the effectiveness of nutritional support is often thwarted by an underlying hostile metabolic milieu. This requires that these metabolic changes be taken into consideration when designing nutritional regimens for such patients. There is also a need to conduct large, multi-center studies to acquire more knowledge of the cost-benefit and cost effectiveness of nutritional support in the critically ill.
Compound 528242: 2,3-Dimethyl-5-propylthiophene

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethyl-5-propylthiophene. Molecular Formula: C9H14S. Molecular Weight: 154.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525990: N1N1-dimethyl-N2-ortho-hydroxyphenylformamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(2-hydroxyphenyl)-N,N-dimethylmethanimidamide. Molecular Formula: C9H12N2O. Molecular Weight: 164.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401414-T1: [Translated] FOODS AND BEVERAGES CONTAINING NIGEROOLIGOSACCHARIDE ALCOHOL.

Starch sugar compositions comprising a plurality of nigerooligosaccharide alcohols may be added to food and drink as at least part of its sweeteners, whereby various advantages can be provided, eg not only a sweetness can be imparted, but also the quality of sweetness can be improved, and the moisture retention of foods can be improved. The nigerooligosaccharide alcohols may be prepared by allowing at least one enzyme selected from a -amylase of various types, an oligosaccharide-forming amylase, a  beta -amylase and a debranching enzyme and an enzyme capable of forming nigerooligosaccharide by transglycosylation and/or condensation reaction to act successively or simultaneously on a material comprised of at least one selected from i) starch, ii) a maltooligosaccharide with a degree of polymerization not lower than maltose and iii) a dextrin, to form nigerooligosaccharide, which is thereafter reduced to obtain a starch sugar composition containing the nigerooligosaccharide alcohol(s).
Patent AT-E399823-T1: [Translated] INK COMPOSITION AND INKJET RECORDING METHOD

An ink composition comprising a dispersion medium and a charged particle, wherein the charged particle comprises a colorant, a compound having pKb of 16 or less in water and containing a proton-acceptive neutral functional group, and a charge controlling agent having pKa of 16 or less in water and containing a proton-donative group.
Pharmacology of airway afferent nerve activity

Afferent nerves in the airways serve to regulate breathing pattern, cough, and airway autonomic neural tone. Pharmacologic agents that influence afferent nerve activity can be subclassified into compounds that modulate activity by indirect means (e.g. bronchial smooth muscle spasmogens) and those that act directly on the nerves. Directly acting agents affect afferent nerve activity by interacting with various ion channels and receptors within the membrane of the afferent terminals. Whether by direct or indirect means, most compounds that enter the airspace will modify afferent nerve activity, and through this action alter airway physiology.
Patent AT-E399809-T1: [Translated] METHOD FOR PRODUCING POLYMER CONJUGATES

The invention relates to a method for preparing a polymer conjugate, in which a water-soluble polymer employed, the polymer having a linear or branched water-soluble polymer backbone and, at one end of the backbone, a branched moiety linked with two free reactive groups capable of covalent bonding to another molecule. Most specificly, it relates to an activated, substantially water soluble poly(ethylene glycol) having a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is branched and has proximal reactive groups is reacted with active moieties in a biologically active agent such as a protein or peptide thus forming conjugates between the activated poly(ethylene glycol) and the biologically active agent.
Patent AT-E401544-T1: [Translated] RADIATORS, ESPECIALLY MULTI-COLUMN RADIATORS

Boiler has many round pipes through which heating medium flows and head pieces (3) at both ends of the round pipes, by means of which the pipes are technically flow-connected to each other. To create a boiler with a sealing connection between the pipes on one hand and the head pieces on the other, each round pipe has an adjustable extension (5) on the head piece side running around the inside of the pipe, pointing in the direction of the respective head piece. Head pieces each have many pipe connections (4) of circular diameter. The end of each connection facing the pipe has an enlarged inner diameter (DISe). A reduced outer diameter (DARr) of each round pipe corresponds to the enlarged inner diameter of the attached pipe connection.
Tribal Courts and Child Welfare: Building Relationships With State Counterparts

This Child Welfare Information Gateway Podcast is available on Apple Podcasts
  
  

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Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525184: Tetrapropylene glycol, diacetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-(2-acetyloxypropoxy)propoxy]propoxy]propyl acetate. Molecular Formula: C16H30O7. Molecular Weight: 334.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526925: iso-Butyladamantyl ketone

Chemical compound data from PubChem database. IUPAC Name: 1-(1-adamantyl)-3-methylbutan-1-one. Molecular Formula: C15H24O. Molecular Weight: 220.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528945: Phenol, 2-(1,1-dimethylpropyl)-4-nitro

Chemical compound data from PubChem database. IUPAC Name: 2-(2-methylbutan-2-yl)-4-nitrophenol. Molecular Formula: C11H15NO3. Molecular Weight: 209.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Service Area PUF - PY2017

The Service Area PUF (SA-PUF) is one of the files that make up the Marketplace PUF. The SA-PUF contains issuer-level data on the geographic coverage or service area (i.e., where the plan is offered) including state, county, and zip code. These data either originate from the Service Area template (i.e., template field), an Excel based form used by issuers to describe their plans in the QHP/SADP application process, or were generated by CCIIO for use in data processing (i.e., system-generated).
Compound 526959: 3-Nitrophenyl-4-nitrophenylacetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(3-nitrophenyl)-2-(4-nitrophenyl)acetate. Molecular Formula: C15H12N2O6. Molecular Weight: 316.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Vedolizumab

Entyvio (vedolizumab) is a prescription biologic medication that blocks certain immune cells from entering the gut, reducing inflammation. It's used to treat moderate to severe ulcerative colitis or Crohn's disease in adults who haven't responded well to other therapies. Available as an intravenous infusion (300 mg) or subcutaneous injection pen (108 mg/0.68 mL). This information was generated using AI and is provided for informational and research purposes only.
Exercise training in heart failure

Chronic heart failure (CHF) is a common condition with a poor prognosis. It is associated with poor exercise tolerance and debilitating symptoms. These symptoms appear to be associated with pathophysiological changes that occur systemically in the patient with CHF. Exercise training in carefully selected patients has been shown to be safe and to improve exercise capacity. Many of the pathophysiological abnormalities of CHF are improved by training. Some studies have suggested a possible improvement in morbidity and mortality with training. This review analyzes the controlled clinical trials of exercise training in CHF published to date.
Seattle: Drug-Related Emergency Department Visits, 2004-2011 - Suicide Attempts

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving suicide attempts in the Seattle metropolitan area, covering 2004-2011.  Drug-related suicide attempts include visits for drug overdoses and for suicide attempts by other means (e.g., using a firearm) if drugs were involved or related to the suicide attempt.
Comparison of two methods based on cross-sectional data for correcting corpus uterine cancer incidence and probabilities

Background
          Two methods are presented for obtaining hysterectomy prevalence corrected estimates of invasive cancer incidence rates and probabilities of the corpus uterine.
        
        
          Methods
          The first method involves cross-sectional hysterectomy data from the Utah Hospital Discharge Data Base and mortality data applied to life-table methods. The second involves hysterectomy prevalence estimates obtained directly from the Utah Behavior Risk Factor Surveillance System (BRFSS) survey.
        
        
          Results
          Hysterectomy prevalence estimates based on the first method are lower than those obtained from the second method through age 74, but higher in the remaining ages. Correction for hysterectomy prevalence is greatest among women ages 75–79. In this age group, the uncorrected rate is 125 (per 100,000) and the corrected rate based on the life-table method is 223 using 1995–97 data, 243 using 1992–94 data, and 228 from the survey method. The uncorrected lifetime probability of developing corpus uterine cancer is 2.6%; the corrected probability from the life-table method using 1995–97 data is 4.2%, using 1992–94 data is 4.5%; and based on prevalence data from the survey method is 4.6%.
        
        
          Conclusions
          Both methods provide reasonable hysterectomy prevalence estimates for correcting corpus uterine cancer rates and probabilities. Because of declining trends in hysterectomy in recent decades, corrected estimates from the life-table method are less pronounced than those based on the survey method. These methods may be useful for obtaining corrected uterine cancer rates and probabilities in areas of the world that do not have sufficient years of hysterectomy data to directly compute prevalence.
Ranitidine

Ranitidine is a generic over-the-counter medication used to relieve heartburn, acid indigestion, and sour stomach. It contains 150 mg of ranitidine hydrochloride per tablet and works by reducing stomach acid production. Manufactured by Dr. Reddy's Laboratories Limited, it's available in various tablet pack sizes. This information was generated using AI and is provided for informational and research purposes only.
NCHS - Birth Rates for Females by Age Group: United States

This dataset includes birth rates for females by age group in the United States since 1940.

The number of states in the reporting area differ historically. In 1915 (when the birth registration area was established), 10 states and the District of Columbia reported births; by 1933, 48 states and the District of Columbia were reporting births, with the last two states, Alaska and Hawaii, added to the registration area in 1959 and 1960, when these regions gained statehood. Reporting area information is detailed in references 1 and 2 below. Trend lines for 1909–1958 are based on live births adjusted for under-registration; beginning with 1959, trend lines are based on registered live births.
Behavioral Health Program Performance Data

The Behavioral Health Program Performance Data provides underlying data for the Mental Health Performance Dashboard covering state fiscal years 2019-2020 to 2023-2024. The California Department of Health Care Services (DHCS) oversees Mental Health Services derived from Medi-Cal claims, encounter, and eligibility systems in accordance with California Welfare and Institutions Code (WIC) § 14707.5 (added as part of Assembly Bill 470 on 10/7/17), and also Specialty Mental Health Services (SMHS) for Medi-Cal members through County Mental Health Plans (MHPs). These services support individuals with serious mental health conditions, helping them manage symptoms and progress toward recovery. DHCS also contracts with Medi-Cal Managed Care Plans (MCPs) for primary, preventive, specialty, and non-specialty mental health services (NSMHS).
2013 CMHS Uniform Reporting System (URS) Tables for Arkansas

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Arkansas for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.