AndreaBozzo/ceres-open-data-index huggingface dataset:
Inhibition of spontaneous induction of lambdoid prophages in

Background
          Infections of bacterial cultures by bacteriophages are serious problems in biotechnological laboratories. Apart from such infections, prophage induction in the host cells may also be dangerous. Escherichia coli is a commonly used host in biotechnological production, and many laboratory strains of this bacterium harbour lambdoid prophages. These prophages may be induced under certain conditions leading to phage lytic development. This is fatal for further cultivations as relatively low, though still significant, numbers of phages may be overlooked. Thus, subsequent cultures of non-lysogenic strains may be infected and destroyed by such phage.
        
        
          Results
          Here we report that slow growth of bacteria decreases deleterious effects of spontaneous lambdoid prophage induction. Moreover, replacement of glucose with glycerol in a medium stimulates lysogenic development of the phage after infection of E. coli cells. A plasmid was constructed overexpressing the phage 434 cI gene, coding for the repressor of phage promoters which are necessary for lytic development. Overproduction of the cI repressor abolished spontaneous induction of the λimm434 prophage.
        
        
          Conclusions
          Simple procedures that alleviate problems with spontaneous induction of lambdoid prophage and subsequent infection of E. coli strains by these phages are described. Low bacterial growth rate, replacement of glucose with glycerol in a medium and overproduction of the cI repressor minimise the risk of prophage induction during cultivation of lysogenic bacteria and subsequent infection of other bacterial strains.
Compound 529056: 2-Isobutyl-4,6-dimethyl-1,3,5-dithiazinane

Chemical compound data from PubChem database. IUPAC Name: 4,6-dimethyl-2-(2-methylpropyl)-1,3,5-dithiazinane. Molecular Formula: C9H19NS2. Molecular Weight: 205.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399988-T1: [Translated] WATER-CHARGING DEVICE WITH A DEVICE FOR CHECKING THE PLANT FORMATION

An apparatus allows monitoring the formation of scale. The apparatus makes it possible to determine the degree of water hardness or a tendency of the degree of water hardness to change over time and to take measures for adjusting the desired degree of water hardness accordingly. A translucent or transparent element has two end surfaces, at least one element emitting an optical signal, and at least one element receiving an optical signal. The element emitting the optical signal and the element receiving the optical signal are directly adjacent to the end surfaces of the transparent element, and the end surfaces are disposed such that they remain free of scale build-up at all times.
Patent AT-E401821-T1: [Translated] HAND-HOLD SCRUBBING DEVICE

Disclosed are hand-held scrubbing devices of the type having a replaceable pad. These devices have a handle which is extruded and extremely flexible. The pads are multi-layer and may be pre-impregnated with a cleaner concentrate. A shipping/docking container for use therewith is also disclosed which has the capability of reducing its overall size once the product has reached the consumer.
Compound 526832: 13-Hydroxy-nonadecanoic, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 13-[tert-butyl(dimethyl)silyl]oxynonadecanoate. Molecular Formula: C26H54O3Si. Molecular Weight: 442.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patients with suspected acute coronary syndrome in a university hospital emergency department: an observational study

Background
          It is widely considered that improved diagnostics in suspected acute coronary syndrome (ACS) are needed. To help clarify the current situation and the improvement potential, we analyzed characteristics, disposition and outcome among patients with suspected ACS at a university hospital emergency department (ED).
        
        
          Methods
          157 consecutive patients with symptoms of ACS were included at the ED during 10 days. Risk of ACS was estimated in the ED for each patient based on history, physical examination and ECG by assigning them to one of four risk categories; I (obvious myocardial infarction, MI), II (strong suspicion of ACS), III (vague suspicion of ACS), and IV (no suspicion of ACS).
        
        
          Results
          4, 17, 29 and 50% of the patients were allocated to risk categories I-IV respectively. 74 patients (47%) were hospitalized but only 19 (26%) had ACS as the discharge diagnose. In risk categories I-IV, ACS rates were 100, 37, 12 and 0%, respectively. Of those admitted without ACS, at least 37% could probably, given perfect ED diagnostics, have been immediately discharged. 83 patients were discharged from the ED, and among them there were no hospitalizations for ACS or cardiac mortality at 6 months. Only about three patients per 24 h were considered eligible for a potential ED chest pain unit.
        
        
          Conclusions
          Almost 75% of the patients hospitalized with suspected ACS did not have it, and some 40% of these patients could probably, given perfect immediate diagnostics, have been managed as outpatients. The potential for diagnostic improvement in the ED seems large.
Compound 527324: 4-Butyl-3,5-dimethoxy-1-phenylpyrazole

Chemical compound data from PubChem database. IUPAC Name: 4-butyl-3,5-dimethoxy-1-phenylpyrazole. Molecular Formula: C15H20N2O2. Molecular Weight: 260.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526807: 18-Hydroxy-nonadecanoic, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 18-[tert-butyl(dimethyl)silyl]oxynonadecanoate. Molecular Formula: C26H54O3Si. Molecular Weight: 442.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529063: Cyclo(Pro-Pro)

Chemical compound data from PubChem database. IUPAC Name: 1,7-diazatricyclo[7.3.0.03,7]dodecane-2,8-dione. Molecular Formula: C10H14N2O2. Molecular Weight: 194.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Motor Vehicle Occupant Death Rate, by Age and Sex, 2012 & 2014, Region 4 - Atlanta

Rate of deaths by age/gender (per 100,000 population) for motor vehicle occupants killed in crashes, 2012 & 2014. 2012 Source: Fatality Analysis Reporting System (FARS). 2014 Source: National Highway Traffic Safety Administration's (NHTSA) Fatality Analysis Reporting System (FARS), 2014 Annual Report File Note: Blank cells indicate data are suppressed. Fatality rates based on fewer than 20 deaths are suppressed.
Compound 526791: 6-Hydroxy-arachidic, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 6-[tert-butyl(dimethyl)silyl]oxyicosanoate. Molecular Formula: C27H56O3Si. Molecular Weight: 456.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Efficacy of Do-It-Yourself Air Filtration Units in Reducing Exposure to Simulated Respiratory Aerosols

Our investigation examined the efficacy of Do-It-Yourself (DIY) air filtration units in reducing recipient exposure to simulated respiratory aerosols within a mock classroom. Seven commercially available box style fans were evaluated using five performance parameters. Two fans with the highest and lowest airflow rates were subsequently evaluated in two DIY unit configurations using either 2.5 or 5 cm deep minimum efficiency reporting value (MERV) 13 filters. DIY air filtration units were tested with the central HVAC system set at 2 air changes/hour (ACH) to represent a classroom with low ventilation. Results of the investigation provide a better understanding of DIY units and their potential to reduce exposure to infectious aerosols that can transmit SARS-CoV-2 and other diseases.

Non-Endorsement Disclaimer:
Mention of any company or product does not constitute endorsement by the National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC).
Patent AT-E399911-T1: [Translated] HOLDING DEVICE FOR ROOF EAVES

The device has mounting plates (6) each of which comprises fasteners that cooperate with maintenance elements of a rear side (10) of a drain board (5) of a roof eave trim (4). The plates have a dissymmetric contour. The fasteners are mounted in rotation with respect to the maintenance elements, between a release position and a locking position. The plates are released from the drain board, in the release position. The mounting plates are integrated with the drain board in a direction perpendicular to a longitudinal axis of the drain board, in the locking position.
Coordinate regulation of RARgamma2, TBP, and TAF

Background
          Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells. Differentiation requires the action of the receptors for all trans, and 9cis-retinoic acid (RAR and RXR, respectively) and is accompanied by growth inhibition, changes in cell morphology, increased apoptosis, proteolytic degradation of the RARγ2 receptor, and induction of target genes.
        
        
          Results
          We show that the RNA polymerase II transcription factor TFIID subunits TBP and TAFII135 are selectively depleted in extracts from differentiated F9 cells. In contrast, TBP and TAFII135 are readily detected in extracts from differentiated F9 cells treated with proteasome inhibitors showing that their disappearance is due to targeted proteolysis. This regulatory pathway is not limited to F9 cells as it is also seen when C2C12 myoblasts differentiate into myotubes. Targeting of TBP and TAFII135 for proteolysis in F9 cells takes place coordinately with that previously reported for the RARγ2 receptor and is delayed or does not take place in RAR mutant F9 cells where differentiation is known to be impaired or abolished. Moreover, ectopic expression of TAFII135 delays proteolysis of the RARγ2 receptor and impairs primitive endoderm differentiation at an early stage as evidenced by cell morphology, induction of marker genes and apoptotic response. In addition, enhanced TAFII135 expression induces a novel differentiation pathway characterised by the appearance of cells with an atypical elongated morphology which are cAMP resistant.
        
        
          Conclusions
          These observations indicate that appropriately timed proteolysis of TBP and TAFII135 is required for normal F9 cell differentiation. Hence, in addition to transactivators, targeted proteolysis of basal transcription factors also plays an important role in gene regulation in response to physiological stimuli.
Behavioral Health Trends in the United States:  Results from the 2014 National Survey on Drug Use and Health (NSDUH)

This national report summarizes findings from the 2014 National Survey on Drug Use and Health (NSDUH) on trends in the behavioral health of people aged 12 years old or older in the civilian, noninstitutionalized population of the United States. It details the rates and numbers of use of illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens, inhalants, and the nonmedical use of prescription-type pain relievers, tranquilizers, stimulants, and sedatives), alcohol, and tobacco products; rates and number of substance use disorders (SUDs); and rates and numbers of persons with any mental illness (AMI), serious mental illness (SMI), and major depressive episode (MDE).Results are provided by age subgroups. Substance use trends are presented for 2002 to 2014, while trends for most mental health issues are reported for 2008 to 2014.Other topics included in the 2014 NSDUH are being published separately as data reviews. These data reviews cover national trends in suicidal thoughts and behavior among adults, substance use treatment, mental health service use, initiation of substance use, and substance use risk and protective factors.
Compound 529377: Disulfide, 1-(1-propenylthio)propyl propyl

Chemical compound data from PubChem database. IUPAC Name: 1-prop-1-enylsulfanyl-1-(propyldisulfanyl)propane. Molecular Formula: C9H18S3. Molecular Weight: 222.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Delaware: 2011-2012 NSDUH

This report presents Delaware\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Requirements for Requirements

This webinar, sponsored by the Children's Bureau's Division of State Systems, was the first webinar in the FY2014 Back to Basics: Procurement and Project Management series. This webinar examined how to write a good business requirement statement and then how to test the soundness of that statement against a definitive list of characteristics. Examples of poorly constructed business requirements were reviewed and the webinar explored what happens once the business requirements document has been completed. The webinar included time for Q&A and audience discussion.

This webinar was moderated by Joyce Rose, consultant to ICF International. The presenter was Mary E. Kernander, Information Technology Manager, State of New Hampshire, Department of Information Technology.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 529291: 3-Hexyne, 2,2,5-trimethyl

Chemical compound data from PubChem database. IUPAC Name: 2,2,5-trimethylhex-3-yne. Molecular Formula: C9H16. Molecular Weight: 124.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Health and Nutrition Examination Survey (NHANES) – Vision and Eye Health Surveillance

1999-2008; 2005-2008. This dataset is a de-identified summary table of vision and eye health data indicators from NHANES, stratified by all available combinations of age group, race/ethnicity, gender, and risk factor. NHANES is a program of studies conducted by the National Center for Health Statistics at CDC designed to assess the health and nutritional status of adults and children in the U.S, and combines interviews and physical examinations. NHANES stopped collecting vision and eye health data in 2008. Approximate sample size is 5,000 persons per year. NHANES data for VEHSS includes questions and examinations related to Visual Function, Vision Exam Measures, Eye Health Conditions, Service Utilization, and Examination Measures. Data were suppressed for cell sizes less than 30 persons, or where the relative standard error more than 30% of the mean. Detailed information on VEHSS NHANES analyses can be found on the VEHSS NHANES webpage (https://www.cdc.gov/visionhealth/vehss/data/national-surveys/national-health-and-nutrition-examination-survey.html). Additional information about NHANES can be found on the NHANES website (https://www.cdc.gov/nchs/nhanes/index.htm). The VEHSS NHANES dataset was last updated in June 2018.
FDA Abbott Infant Formula Recall

On September 22, 2010, Abbott issued a voluntary recall of certain Similac powdered infant formula after identifying a common warehouse beetle (both larvae and adults) in the finished product at their Sturgis, Michigan plant. The company immediately put all product manufactured at the Michigan plant on hold and ceased manufacturing at that location. FDA has advised against consumption of the recalled product and urged consumers to follow the manufacturer's instructions for reporting and returning the formula.
Compound 525491: 5,5-Dimethyl-4-thia-1-hexyne

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-prop-2-ynylsulfanylpropane. Molecular Formula: C7H12S. Molecular Weight: 128.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526164: Diethyl 3-bromophenyl phosphate

Chemical compound data from PubChem database. IUPAC Name: (3-bromophenyl) diethyl phosphate. Molecular Formula: C10H14BrO4P. Molecular Weight: 309.09. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525605: N,N-Dimethyl-N'-(4-methylphenyl)-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N,N,4-trimethyl-N'-(4-methylphenyl)benzenecarboximidamide. Molecular Formula: C17H20N2. Molecular Weight: 252.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525516: 3-Methoxy-4-benzyloxyphenylacetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(3-methoxy-4-phenylmethoxyphenyl)acetate. Molecular Formula: C17H18O4. Molecular Weight: 286.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Information Memorandum (IM-02-06)

This Information Memorandum (IM) announces extensions and informs State officials and other interested parties of Title IV-E Child Welfare Demonstration Projects Requests for Extensions - Procedures and Criteria. Effective September 22, 2017, the guidance in this IM has been superseded by ACYF-CB-IM-17-04.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 526287: 1,3,9-Tribromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,3,9-tribromodibenzofuran. Molecular Formula: C12H5Br3O. Molecular Weight: 404.88. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Seattle: Drug-Related Emergency Department Visits, 2004-2011 - Seeking Detox

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving patients seeking detox in the Seattle metropolitan area, covering 2004-2011. This includes nonemergency requests made through the ED for admission to detoxification unit, visits to obtain medical clearance before being incarcerated, and acute emergencies where an individual is experiencing withdrawal symptoms and requests detox. These estimates do not include patients who seek or enter the hospital\'s detox unit through other avenues.
Compound 529400: 1,3-Dioxolane, 4-methyl-2-(1-methylpropyl)-

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-yl-4-methyl-1,3-dioxolane. Molecular Formula: C8H16O2. Molecular Weight: 144.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2011 CMHS Uniform Reporting System (URS) Output Tables for Indiana

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Patent AT-E40068-T1: [Translated] SUPPORT DEVICE FOR ROBOT WITH PORTAL CARRIAGE MOVABLE ON RAILS.

The invention relates to a robot carrier structure constituted by a portal wagon (10) movable on rails (12, 13) and supported at its flanks by two carriages (20, 20 min ) each comprising two wheels (21, 22) longitudinally coupled by motion transmission means (25, 28, 30; 26, 29, 31) actuated in synchronism by an electric motor (27). The two electric motors (27) of the two carriages (20, 20 min ) further are so connected as to constitute an electric axis. n<??>Each wheel (21, 22) has a structure adapted to ensure a high adherence to the rail (12, 13), particularly due to the provision of a pair of rings (45, 46) of elastomeric material engaging the rolling surface (47) of the rail (12, 13).
Compound 526882: 2-[2-(2-Isopentoxyethoxy)ethoxy]ethyl trifluoroacetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-(3-methylbutoxy)ethoxy]ethoxy]ethyl 2,2,2-trifluoroacetate. Molecular Formula: C13H23F3O5. Molecular Weight: 316.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Sources of nonlinearity in cDNA microarray expression measurements

Background
          A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the corresponding genes. To test this assumption, we experimentally examined the relationship between signal and expression for the two types of microarrays we most commonly encounter: radioactively labeled cDNAs on nylon membranes and fluorescently labeled cDNAs on glass slides.
        
        
          Results
          We uncovered two sources of nonlinearity. The first, which led to discrepancies in analysis affecting the fluorescent signals, was signal quenching associated with excessive dye concentrations. The second, affecting the radioactive signals, was a nonlinear transformation of the raw data introduced by the scanner. Correction for this transformation was made by some, but not all, image-quantification software packages.
        
        
          Conclusions
          The second type of nonlinearity is more troublesome, because it could not have been predicted a priori. Both types of nonlinearities were detected by simple dilution series, which we recommend as a quality-control step.
Compound 527206: 2-((4aS,8R,8aR)-4a,8-Dimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-2-yl)propan-2-ol

Chemical compound data from PubChem database. IUPAC Name: 2-(4a,8-dimethyl-4,5,6,7,8,8a-hexahydro-3H-naphthalen-2-yl)propan-2-ol. Molecular Formula: C15H26O. Molecular Weight: 222.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.