AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 527686: Butanoic acid, 3-chloro, 1-methyl-3-butenyl ester

Chemical compound data from PubChem database. IUPAC Name: pent-4-en-2-yl 3-chlorobutanoate. Molecular Formula: C9H15ClO2. Molecular Weight: 190.67. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400308-T1: [Translated] IMPROVED OSTEOINDUCTIVE MATERIALS

The present invention relates to an osteoinductive material comprising a matrix material with morphogenetic protein(s) absorbed on inner or outer surfaces of this matrix material, wherein the osteoinductive material is obtainable by contacting the matrix material and the morphogenetic protein(s) under conditions of pH and ionic concentration to keep the protein stable and dissolved in a solution until dried and thereby allowing that the matrix material becomes evenly coated with the morphogenetic protein(s). <IMAGE>
Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth

Background
          The outgrowth of new vessels – angiogenesis – in the tumour mass is considered to be a limiting factor of tumour growth. To inhibit the matrix lysis that is part of the tumour angiogenesis, we employed the chimeric protein mhATF-BPTI, composed of the receptor binding part of the urokinase (ATF) linked to an inhibitor of plasmin (BPTI).
        
        
          Methods
          For delivery, recombinant adenovirus encoding the transgene of interest was injected intravenously or locally into the tumour. The anti tumour effect of this compound was compared to that of human endostatin and of mhATF alone in two different rat bronchial carcinomas growing either as subcutaneous implants or as metastases.
        
        
          Results
          Significant inhibition of the tumour growth and decrease of the number of lung metastasis was achieved when the concentration of mhATF-BPTI at the tumour site was above 400 of ng / g tissue. This concentration could be achieved via production by the liver, only if permissive to the recombinant adenovirus. When the tumour cells could be transduced, local delivery of the vector was enough to obtain a response. In the case of metastasis, the capacity of the lung tissue to concentrate the encoded protein was essential to reach the required therapeutic levels. Further, endostatin or mhATF could not reproduce the effects of mhATF-BPTI, at similar concentrations (mhATF) and even at 10-fold higher concentration (endostatin).
        
        
          Conclusion
          The ATF-BPTI was shown to inhibit tumour growth of different rat lung tumours when critical concentration was reached. In these tumour models, endostatin or ATF induce almost no tumour response.
Compound 525509: 7-Methyl-4-thiaoctane

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-1-propylsulfanylbutane. Molecular Formula: C8H18S. Molecular Weight: 146.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Table 3. Marijuana Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 3. Marijuana Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Compound 525812: N,N'-bis-(4-Methoxyphenyl)formamidine

Chemical compound data from PubChem database. IUPAC Name: N,N'-bis(4-methoxyphenyl)methanimidamide. Molecular Formula: C15H16N2O2. Molecular Weight: 256.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Boston: Drug-Related Emergency Department Visits, 2004-2011 - Adverse Reactions

Excel file with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving adverse reactions in the Boston metropolitan area. It includes ED visits in which an adverse health consequence (e.g., side effects or an allergic reaction) resulted when taking prescription drugs, over-the-counter medications, or dietary supplements as prescribed or recommended.  This analytic category does not include drug misuse or abuse.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.
Child and Family Services Reviews Update Volume 17, Issue 3, June 2023

This issue of Child and Family Services Reviews Update contains the following sections:CFSR Round 4 Is Underway!, APSR Process Integrated With CFSP, New OSRI Course Released on E-Learning Academy, New CFSR Overview Video Released, Spanish Translations Added to Portal, and New Round 4 FAQs Posted.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 527762: 2,2-Dichloroethyl nonadecanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl nonadecanoate. Molecular Formula: C21H40Cl2O2. Molecular Weight: 395.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400016-T1: [Translated] METHOD AND SYSTEM FOR DETECTING UNAUTHORIZED USE OF A COMMUNICATIONS NETWORK

A system for detecting unauthorised use of a network is provided with a pattern matching engine for searching attack signatures into data packets, and with a response analysis engine for detecting response signatures into data packets sent back from an attacked network/computer. When a suspect signature has been detected into a packet, the system enters an alarm status starting a monitoring process on the packets sent back from the potentially attacked network/computer. An alarm is generated only in case the analysis of the response packets produces as well a positive result. Such intrusion detection system is much less prone to false positives and misdiagnosis than a conventional pattern matching intrusion detection system.
The diagnostic value of liver biopsy

Background
          Since the introduction of molecular diagnostic tools such as markers for hepatitis C and different autoimmune diseases, liver biopsy is thought to be useful mainly for staging but not for diagnostic purposes. The aim was to review the liver biopsies for 5 years after introduction of testing for hepatitis C, in order to evaluate what diagnostic insights – if any – remain after serologic testing.
        
        
          Methods
          Retrospective review of all liver biopsies performed between 1.1.1995 and 31.12.1999 at an academic outpatient hepatology department. The diagnoses suspected in the biopsy note were compared with the final diagnosis arrived at during a joint meeting with the responsible clinicians and a hepatopathologist.
        
        
          Results
          In 365 patients, 411 diagnoses were carried out before biopsy. 84.4 % were confirmed by biopsy but in 8.8 %, 6.8 % and 10.5 % the diagnosis was specified, changed or a diagnosis added, respectively. Additional diagnoses of clinical relevance were unrecognized biliary obstruction and additional alcoholic liver disease in patients with chronic hepatitis C. Liver biopsy led to change in management for 12.1 % of patients.
        
        
          Conclusion
          Even in the era of advanced virological, immunological and molecular genetic testing, liver biopsy remains a useful diagnostic tool. The yield is particularly high in marker negative patients but also in patients with a clear-cut prebiopsy diagnosis, liver biopsy can lead to changes in patient management.
Compound 530444: 4-Butylbenzoic acid, cyclobutyl ester

Chemical compound data from PubChem database. IUPAC Name: cyclobutyl 4-butylbenzoate. Molecular Formula: C15H20O2. Molecular Weight: 232.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527763: 2,2-Dichloroethyl nonanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl nonanoate. Molecular Formula: C11H20Cl2O2. Molecular Weight: 255.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526336: 2,4-Dibromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,4-dibromodibenzofuran. Molecular Formula: C12H6Br2O. Molecular Weight: 325.98. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527803: 2,2,2-Trichloroethyl 3-chlorobenzoate

Chemical compound data from PubChem database. IUPAC Name: 2,2,2-trichloroethyl 3-chlorobenzoate. Molecular Formula: C9H6Cl4O2. Molecular Weight: 287.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529011: 1,2-Diethyl-3,5-dimethylbenzene

Chemical compound data from PubChem database. IUPAC Name: 1,2-diethyl-3,5-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2010 State Profile — Colorado

This state profile includes data from facilities in Colorado that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Colorado. In Colorado, 437 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 39,749 clients in substance abuse treatment on March 31, 2010. The survey response rate in Colorado was 88.3%.
Patent AT-E401292-T1: [Translated] METHOD FOR THE CONTINUOUS PRODUCTION OF ALDEHYDES

The invention relates to a method for the continuous production of aldehydes by the isomerising hydroformylation in a homogenous phase of olefin compositions by means of a synthesis gas, in the presence of a homogeneous rhodium catalyst that is complexed with an organophosphorus ligand containing oxygen atoms and/or nitrogen atoms and a free ligand. The production is carried out at high temperature and high pressure in a multi-stage reaction system consisting of at least two reaction zones. According to the method, the olefin composition is first reacted in a first reaction zone or a group of several first reaction zones at a total pressure of between 10 and 40 bar, using a synthesis gas with a CO/H2 molar ratio of between 4:1 and 1:2 until a 40 to 95% conversion of the alpha-olefins is obtained.
DASH – School Health Profiles (Profiles)

2022 School Health Profiles (Profiles) Dataset. Profiles is a system of surveys assessing school health policies and practices in states, school districts, territories, and tribes.  Profiles surveys are conducted biennially by education and health agencies among middle and high school principals and lead health education teachers. Profiles monitors the current status of school health education requirements and content, physical education and physical activity, practices related to bullying and sexual harassment, school health policies related to tobacco-use prevention and nutrition, school-based health and mental health services, family engagement and community involvement, and school health coordination.
Compound 529314: Oxetane, 3-hydroxymethyl-3-iodomethyl

Chemical compound data from PubChem database. IUPAC Name: [3-(iodomethyl)oxetan-3-yl]methanol. Molecular Formula: C5H9IO2. Molecular Weight: 228.03. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hydrocortisone sodium succinate

Hydrocortisone sodium succinate is a generic injectable corticosteroid medication used to treat inflammation, allergies, and certain medical conditions. It is administered by intramuscular or intravenous injection, with each vial containing 100 mg of the active ingredient. Manufactured by Cipla USA Inc. under application ANDA214050. This information was generated using AI and is provided for informational and research purposes only.
Compound 526743: 2-(Nonyloxy)ethanol, TFA

Chemical compound data from PubChem database. IUPAC Name: 2-nonoxyethyl 2,2,2-trifluoroacetate. Molecular Formula: C13H23F3O3. Molecular Weight: 284.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Survey of Substance Abuse Treatment Services: State Profiles 2008

The 2008 National Survey of Substance Abuse Treatment Services (N-SSATS) is an annual survey of facilities providing substance abuse treatment. The N-SSATS, conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), is designed to collect data on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse facilities (both public and private) throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.
Casimersen

AMONDYS 45 (casimersen) is an intravenous solution used to treat Duchenne muscular dystrophy in patients with a specific genetic mutation. It works as an antisense oligonucleotide to increase protein synthesis. Manufactured by Sarepta Therapeutics, Inc., it's available as a 50 mg/mL injection in single-use vials. This information was generated using AI and is provided for informational and research purposes only.
Compound 530152: Trimethylsilyl 3-methoxybenzoate

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 3-methoxybenzoate. Molecular Formula: C11H16O3Si. Molecular Weight: 224.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401588-T1: [Translated] CAMERA

The object of the present invention is to eliminate hitherto restrictive conditions related to photography, like when attempting to register pictures with infinite depth of field, more or less, or attempt full detail-reproduction of light and shade. This is, according to the present invention, accomplished by making several recordings with differing states of focus or exposure, the images registered being similarly subdivided into smaller image-parts and a resultant image bing produced by selecting those image-parts from each set, being most suitable. Optimal image definition of an image-part can for instance be assessed by contrast-measurement techniques or separate range-finding with a laser. An analogous optimal representation of image detail can also be achieved.
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature

Because angiogenesis plays a major role in the perpetuation of inflammatory arthritis, we explored a method for selectively targeting and destroying new synovial blood vessels. Mice with collagen-induced arthritis were injected intravenously with phage expressing an RGD motif. In addition, the RGD peptide (RGD-4C) was covalently linked to a proapoptotic heptapeptide dimer, D(KLAKLAK)2, and was systemically administered to mice with collagen-induced arthritis. A phage displaying an RGD-containing cyclic peptide (RGD-4C) that binds selectively to the αvβ3 and αvβ5 integrins accumulated in inflamed synovium but not in normal synovium. Homing of RGD-4C phage to inflamed synovium was inhibited by co-administration of soluble RGD-4C. Intravenous injections of the RGD-4C–D(KLAKLAK)2 chimeric peptide significantly decreased clinical arthritis and increased apoptosis of synovial blood vessels, whereas treatment with vehicle or uncoupled mixture of the RGD-4C and the untargeted proapoptotic peptide had no effect. Targeted apoptosis of synovial neovasculature can induce apoptosis and suppress clinical arthritis. This form of therapy has potential utility in the treatment of inflammatory arthritis.
Compound 526822: 15-Hydroxy-nonadecanoic, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 15-[tert-butyl(dimethyl)silyl]oxynonadecanoate. Molecular Formula: C26H54O3Si. Molecular Weight: 442.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
What you should know about PR3-ANCA: Evidence for the role of T cells in the pathogenesis of systemic vasculitis

The pathogenesis of systemic vasculitis is complex and is likely to involve many mechanisms. There is a growing body of evidence that T cells may contribute to the pathogenesis of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Predominantly, T cells and monocytes are found in inflammatory infiltrates in patients with Wegener's granulomatosis (WG). The production of ANCA appears to be T-cell-dependent. T lymphocytes from the peripheral blood of patients with ANCA-associated vasculitis have been shown to proliferate in response to proteinase 3 (PR3). These and other findings outlined in this review indicate T-cell involvement, although further studies are still needed to elucidate the exact contribution of T cells to the pathogenesis of systemic vasculitis.
National Survey of Substance Abuse Treatment Services: State Profiles 2005

The 2005 National Survey of Substance Abuse Treatment Services (N-SSATS) is an annual survey of facilities providing substance abuse treatment. The N-SSATS, conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), is designed to collect data on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse facilities (both public and private) throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.
AFDC Caseload Data 1960 – 1995

The Aid to Families with Dependent Children (AFDC) program is the predecessor program to the TANF program (switched in 1997). The program provided financial aid to children of low income families. Data is available for years from 1960 to 1995. Average monthly counts for number of cases, total recipients, children recipients, and adult recipients (3 sets of these reports: Total, Basic, and Unemployed Parent). Reports have data columns for both fiscal and calendar year average monthly counts.

<b>Units of Response: </b>State AFDC Programs

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>No

<b>COVID-19 Data: </b>No

<b>Periodicity: </b>Annual

<b>SORN: </b>https://www.federalregister.gov/documents/2015/04/02/2015-07440/privacy-act-of-1974-system-of-records-notice

<b>Data Use Agreement: </b>https://www.icpsr.umich.edu/rpxlogin

<b>Data Use Agreement Location: </b>Unavailable

<b>Equity Indicators: </b>Unavailable

<b>Granularity: </b>Unavailable

<b>Spatial: </b>United States

<b>Geocoding: </b>State
Patent AT-E40169-T1: [Translated] FRAME CONSTRUCTION.

A frame structure consisting of two compound units provided with mutually facing grooves undercut on either side, in which the first compound unit can be attached in a desired position to the second compound unit via a detachable coupling which comprises a turning part which can be turned from the outside manually via a handle about its longitudinal axis by about 90 DEG  into its coupling or decoupling position, and which in its coupling position positively engages by means of a T-head at its one end in one of the two grooves and by means of anchoring means at its other end in the other of the two grooves and can be locked in this coupling position by means of an anti-rotation device. To connect the two compound units to each other without special tools, but above all to be able also to detach them from each other again, it is proposed according to the invention that the anchoring means comprise a punched part which is arranged longitudinally displaceably in the one groove and bears the turning part which is freely rotatable relative to it and that the handle comprise a resilient element connected securely against rotation to the turning part, which element in decoupling position extends in relieved state or under only slight stress between the two compound units and in coupling position engages under bending stress behind a holder.
A revival of the B cell paradigm for rheumatoid arthritis pathogenesis?

Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of the rheumatoid factor they produced, was initially invoked. In more recent years, recognition of antigens in the joint by T cells sparking an inflammatory cascade has been a more favored interpretation. Here, we re-examine some of the arguments that underpin this proposed role of joint T cells, in light of recent results from transgenic mice in which a self-reactive T-cell receptor provokes disease, but from outside the joint and indirectly via B lymphocytes and immunoglobulins.
Biventricular pacing in heart failure: update on results from clinical trials

Biventricular pacing or resynchronisation therapy is a non-pharmacological therapy for patients with chronic heart failure. Since being originally described in 1994, biventricular pacing has become a subject of intense interest and investigation. This review analyses the results reported in observational series and randomised trials, and seeks to answer two questions. If it works, why does it work? Which heart failure patients will it benefit?
Importance of the TIMI frame count: implications for future trials

Although the TIMI (Thrombolysis In Myocardial Infarction) flow grade classification scheme is widely used to assess angiographic outcomes, it is limited by poor reproducibility and its categoric nature. The corrected TIMI frame count (CTFC) is a simple, more objective continuous variable index of coronary blood flow that can be broadly and inexpensively applied. This measure of the time for dye to traverse a coronary artery is both accurate (highly correlated with Doppler velocity measurements) and precise (reproducible). The method has been prospectively validated as providing independent risk stratification above and beyond the conventional TIMI flow grades. It has been shown to be a predictor of restenosis, and has been of value in elucidating the underlying pathophysiology of acute myocardial infarction. In view of the above and its ease of use, we anticipate that CTFC will become a widely used method to evaluate coronary blood flow.