AndreaBozzo/ceres-open-data-index huggingface dataset:
High copy arrays containing a sequence upstream of

Background
          The Caenorhabditis elegans gene mec-3 encodes a LIM-homeodomain protein that is a master regulator of touch receptor neuron genes. Two of the touch neurons, the ALM neurons, are generated in the anterior of the animal and then migrate to near the middle of the animal. In animals transformed with a sequence upstream of mec-3, the ALM touch receptor neurons failed to migrate to their normal positions and sometimes migrated in the wrong direction, and the PLM touch receptor neurons showed axonal defects. Here we characterize this effect and identify the sequence causing the cell migration and axonal defects.
        
        
          Results
          The ALM migration defect did not result from RNA interference (RNAi), nonspecific effects of carrying a transgenic array, expression of GFP, or the marker gene used to make the transformants. Instead, the ALM migration defect resulted from transgenic arrays containing many copies of a specific 104 bp DNA sequence. Transgenic arrays containing this sequence did not affect all cell migrations.
        
        
          Conclusions
          The mec-3 upstream sequence appeared to be sequestering (titrating out) a specific DNA-binding factor that is required for the ALMs to migrate correctly. Because titration of this factor could reverse the direction of ALM migrations, it may be part of a program that specifies both the direction and extent of ALM migrations. mec-3 is a master regulator of touch receptor neuron genes, so the factor or factors that bind this sequence may also be involved in specifying the fate of touch receptor neurons.
Compound 529765: 4-Methylpentyl trichloroacetate

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-1,3-dithiepane. Molecular Formula: C6H12S2. Molecular Weight: 148.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table 1C. Arboviral diseases, St. Louis encephalitis virus disease to West Nile virus disease

NNDSS - Table 1C. Arboviral diseases, St. Louis encephalitis virus disease to West Nile virus disease - 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:
•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.
Footnotes:
*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
AH Provisional COVID-19 Deaths by HHS Region, Race, and Age, 2015 to date

Deaths from all causes and deaths involving coronavirus disease 2019 (COVID-19) reported to NCHS by time-period, HHS region, race and Hispanic origin, and age group.

United States death counts include the 50 states, plus the District of Columbia and New York City. The ten (10) United States Department of Health and Human Services (HHS) regions include the following jurisdictions. Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont; Region 2: New Jersey, New York, New York City, Puerto Rico; Region 3: Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, West Virginia; Region 4: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, Tennessee; Region 5: Illinois, Indiana, Michigan, Minnesota, Ohio, Wisconsin; Region 6: Arkansas, Louisiana, New Mexico, Oklahoma, Texas; Region 7: Iowa, Kansas, Missouri, Nebraska; Region 8: Colorado, Montana, North Dakota, South Dakota, Utah, Wyoming; Region 9: Arizona, California, Hawaii, Nevada; Region 10: Alaska, Idaho, Oregon, Washington.
Compound 526476: Barbituric acid, 5-propyl-5-(2-methylpropyl)

Chemical compound data from PubChem database. IUPAC Name: 5-(2-methylpropyl)-5-propyl-1,3-diazinane-2,4,6-trione. Molecular Formula: C11H18N2O3. Molecular Weight: 226.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528867: 1-(Prop-1-enyldisulfanyl)-1-(propyldisulfanyl)propane

Chemical compound data from PubChem database. IUPAC Name: 1-(prop-1-enyldisulfanyl)-1-(propyldisulfanyl)propane. Molecular Formula: C9H18S4. Molecular Weight: 254.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399977-T1: [Translated] OPTICAL PROBE AND APPARATUS AND METHOD USING THE SAME

The probe comprises a light source (20), means for shaping (24, 25, 21) the beam emitted by said light source and the beam coming from a surface arranged close to a target distance, an optical detector unit (22), comprising a pinhole diaphragm (26) and a photoelectric detector (28), providing a voltage peak (31) when said surface is at said target distance and further comprising a diaphragm (27) with a hole larger than said pinhole and a photoelectric detector (29), providing a voltage greater than that produced by said detection sensor (28), except when said surface is a the target distance. The method uses the probe to measure the thickness of an optical lens.
Role of bedside electroencephalography in the adult intensive care unit during therapeutic neuromuscular blockade

Background:
          Size, weight and technical difficulties limit the use of ponderous strip chart electroencephalographs (EEGs) for real time evaluation of brain wave function in modern intensive care units (ICUs). Portable, computer processed, bedside EEGs provide real time brain wave appraisal for some brain functions during therapeutic neuromuscular blockade when the visual clues of the cerebral function disappear.
        
        
          Results:
          Critically ill ICU patients are frequently placed in suspended animation by neuromuscular blockade to improve hemodynamics in severe organ system failure. Using the portable bedside EEG monitor, several cerebral functions were monitored continuously during sedation of selected patients in our ICU.
        
        
          Conclusions:
          The processed EEG is able to continuously monitor the end result of some therapeutics at the neuronal level when natural artifacts are suppressed or eliminated by neuromuscular blockade. Computer processed EEG monitoring may be the only objective method of assessing and controlling sedation during therapeutic musculoskeletal paralysis.
Cholinergic and GABAergic pathways in fly motion vision

Background
          The fly visual system is a highly ordered brain structure with well-established physiological and behavioral functions. A large number of interneurons in the posterior part of the third visual neuropil, the lobula plate tangential cells (LPTCs), respond to visual motion stimuli. In these cells the mechanism of motion detection has been studied in great detail. Nevertheless, the cellular computations leading to their directionally selective responses are not yet fully understood. Earlier studies addressed the neuropharmacological basis of the motion response in lobula plate interneurons. In the present study we investigated the distribution of the respective neurotransmitter receptors in the fly visual system, namely nicotinic acetylcholine receptors (nAChRs) and GABA receptors (GABARs) demonstrated by antibody labeling.
        
        
          Results
          The medulla shows a laminar distribution of both nAChRs and GABARs. Both receptor types are present in layers that participate in motion processing. The lobula also shows a characteristic layering of immunoreactivity for either receptor in its posterior portion. Furthermore, immunostaining for nAChRs and GABARs can be observed in close vicinity of lobula plate tangential cells. Immunostaining of GABAergic fibers suggests that inhibitory inputs from the medulla are relayed through the lobula to the lobula plate rather than through direct connections between medulla and lobula plate.
        
        
          Conclusions
          The interaction of excitatory and inhibitory pathways is essential for the computation of visual motion responses and discussed in the context of the Reichardt model for motion detection.
Compound 525898: N,N-Dimethyl-N'-cyclohexyl-isobutyramidine

Chemical compound data from PubChem database. IUPAC Name: N'-cyclohexyl-N,N,2-trimethylpropanimidamide. Molecular Formula: C12H24N2. Molecular Weight: 196.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2014 CMHS Uniform Reporting System (URS) Table for Pennsylvania

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Pennsylvania. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
NCHS - Births and General Fertility Rates: United States

This dataset includes crude birth rates and general fertility rates in the United States since 1909. 

The number of states in the reporting area differ historically. In 1915 (when the birth registration area was established), 10 states and the District of Columbia reported births; by 1933, 48 states and the District of Columbia were reporting births, with the last two states, Alaska and Hawaii, added to the registration area in 1959 and 1960, when these regions gained statehood. Reporting area information is detailed in references 1 and 2 below. Trend lines for 1909–1958 are based on live births adjusted for under-registration; beginning with 1959, trend lines are based on registered live births.
National Health and Nutrition Examination Survey (NHANES) Restricted Data: 1999 to Present

The <b>National Health and Nutrition Examination Survey</b> (NHANES) is designed to assess the health and nutritional status of adults and children in the United States. The survey is unique in that it combines interviews with standardized physical examinations and laboratory tests. <br>
NHANES was conducted on a periodic basis from 1971 to 1994. In 1999 NHANES became continuous. Every year, approximately 5,000 people of all ages are interviewed in their homes and complete the health examination conducted in a mobile examination center. <br>
The NHANES interview includes demographic, socioeconomic, dietary, and health-related questions. The examination component consists of medical, dental, and physiological measurements, as well as the collection of biospecimens, such as blood and urine for laboratory testing.

This set of restricted data contains indirect identifying and/or sensitive information collected in <b>continuous NHANES since 1999</b>. Please refer to the links below for additional data available from NHANES:  
<ul><li><a href="https://wwwn.cdc.gov/nchs/nhanes/Default.aspx">NHANES Public Use Data at: https://wwwn.cdc.gov/nchs/nhanes/Default.aspx</a></li>
<li><a href="https://data.cdc.gov/dataset/National-Health-and-Nutrition-Examination-Survey-N/hdx4-e4uu">NHANES Genetic Restricted Data at: https://data.cdc.gov/dataset/National-Health-and-Nutrition-Examination-Survey-N/hdx4-e4uu</a></li>
<li><a href="https://data.cdc.gov/dataset/National-Health-and-Nutrition-Examination-Survey-N/ic32-yq9m">NHANES Restricted Data: Prior to 1999 at: https://data.cdc.gov/dataset/National-Health-and-Nutrition-Examination-Survey-N/ic32-yq9m</a></li>
<li><a href="https://data.cdc.gov/dataset/3-NHANES-National-Youth-Fitness-Survey-NNYFS-Restr/5u84-m4rs">NHANES National Youth Fitness Survey (NNYFS) Restricted Data at: https://data.cdc.gov/dataset/3-NHANES-National-Youth-Fitness-Survey-NNYFS-Restr/5u84-m4rs</a></li> </ul>
Please refer to the <a href="https://wwwn.cdc.gov/nchs/nhanes/analyticguidelines.aspx">NHANES Analytic Guidelines at: https://wwwn.cdc.gov/nchs/nhanes/analyticguidelines.aspx</a> and the on-line <a href="https://wwwn.cdc.gov/nchs/nhanes/tutorials/default.aspx">NHANES Tutorial at: https://wwwn.cdc.gov/nchs/nhanes/tutorials/default.aspx</a> for further details on the survey design, implementation, and data analysis.
Patent AT-E400083-T1: [Translated] DEVICE FOR SUPPRESSING THE RECEIPT OF VEHICLE EMITTED INTERFERENCE RADIATION

The radio reception unit has an antenna (1), a receiver (2) and an interference signal reception device (29). There is a coupling element (3) for receiving the pulsed interference signal (11) emitted by the automobile and an evaluation circuit (4) for providing a signal (7) indicating the interference, used for controlling a signal transmission element (6) within the receiver.
Adolescent Outcome of Physically Abused Schoolchildren

This study is designed to assess the outcomes in mid to late adolescence of preadolescent physically abused and matched non-maltreated children first studied at ages 9-12 years. The outcome domains were Externalizing Problem Behavior, Internalizing Problems and Emotional Disorder, Quality of Personal Relationships, Risk Behavior, and Aggression/Delinquency. For each, a model was proposed in which the path from preadolescent physical abuse to outcome is examined with respect to three classes of mediating variables hypothesized to protect against or exacerbate the effects of the abuse. These classes of mediators, comprised of variables chosen on the basis of the contributors' previous abuse studies and other data in the child development literature, were all measured in preadolescence. They are conceptualized as individual (e.g., behavior problems, social behavior, social cognition), interpersonal (e.g., social status among peers, attachment, parenting), and contextual (e.g., family adversity, maternal psychopathology). Each model is retested with preadolescent exposure to family violence and parental perceptions of community violence added to child abuse as the causal variable. The children studied as adolescents were re-recruited from the 100 confirmed cases of physical abuse first recruited when they were preadolescents from the NYC Child Welfare Administration Register and 100 non-maltreated classmates matched case by case for gender, age, ethnicity, and SES. They were assessed in preadolescence by means of classroom sociometry and peer behavior ratings, by individual child interviews, by teacher and parent ratings of behavior, and by parent interviews and questionnaires on family demographics, adversity, family conflict, including domestic violence, and on parenting discipline practices. The assessments of outcome, as close as possible to age 17, were carried out by means of adolescent interviews and questionnaires, teacher and parent ratings, parent interviews and questionnaires, and an interview and questionnaire administered to a best friend of each adolescent.Preliminary results show that the abused adolescents continue to be at higher risk than controls for a variety of poor outcomes such as behavior problems, depression, delinquency, and some high-risk behaviors. It also appears that they are more likely to be exposed to family violence in adolescence.Not all abused children have poor outcomes, but as a group, they are demonstrably at risk. This study's main purpose was to identify some important factors influencing the path from preadolescent abuse to adolescent outcome and thereby to target possible points where intervention in childhood might avert some of abuse's costly individual and societal consequences. Those analyses are currently underway.

Investigators: Suzanne Salzinger, Ph.D.New York State Psychiatric Institute, New York, NYRichard Feldman, Ph.D.New York State Psychiatric Institute, New York, NYDaisy S. Ng-Mak, Ph.D.Columbia University, New York, NY
Compound 526610: 1-O-Acetyl-2,6-anhydro-3,4,5-tri-O-methylhexitol

Chemical compound data from PubChem database. IUPAC Name: (3,4,5-trimethoxyoxan-2-yl)methyl acetate. Molecular Formula: C11H20O6. Molecular Weight: 248.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - TABLE 1AA. Poliovirus infection, nonparalytic to Psittacosis

NNDSS - TABLE 1AA. Poliovirus infection, nonparalytic to Psittacosis - 2021. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notice: Due to data processing issues at CDC, data for the following jurisdictions may be incomplete for week 7: Alaska, Arizona, California, Connecticut, Delaware, Florida, Hawaii, Louisiana, Maryland, Michigan, Missouri, North Dakota, New Hampshire, New York City, Oregon, Pennsylvania, and Rhode Island.

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
 Max: Maximum — Maximum case count during the previous 52 weeks.
  * Case counts for reporting years 2020 and 2021 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf. 
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
Patent AT-E400034-T1: [Translated] OPTICAL SCANNING PEN, SCANNING MODULE AND METHOD OF USE

A high speed non-contact beam scanning device sized and shaped to provide the ergonomic benefits of a pen or wand, yet can scan a wide angle moving beam across an information-bearing target in one or two dimensional scan patterns such as lines, rasters or other patterns in order to read information therefrom. The device is well suited for reading one or two dimensional bar-code or other printed matter. In order to achieve the high density optical packaging necessary for its high performance to size benefits the device employs a novel in-line or "axial" gyrating, or "axial" scan element. The axial scan element can accept an input light beam at one end and cause it to emerge from its opposite end as a scanned beam, propagating in the same general forward direction it had upon entering the element. Reflected light, which carries information contained on the target, is collected by an internal non-imaging light concentrator and is processed by signal processing electronics. All components are integrated into a thin low mass module small enough to fit in a pen. Communication from the device is achievable by a cable or by wireless transmission.
Compound 526054: Trimethylsilylestrone

Chemical compound data from PubChem database. IUPAC Name: 13-methyl-3-trimethylsilyloxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one. Molecular Formula: C21H30O2Si. Molecular Weight: 342.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.