AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E399869-T1: [Translated] IMPROVED BACILLUS HOST CELL

A  Bacillus licheniformis  mutant host cell derived from a parent B.  licheniformis  host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s) which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO 166, wherein the mutant host cell secretes at least 5% less of the one or more secreted polypeptide(s) than the parent host cell, when they are cultivated under comparable conditions.
Compound 525615: N,N-Dimethyl-N'-butyl-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-butyl-4-chloro-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C13H19ClN2. Molecular Weight: 238.75. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Behavioral Health Barometer: State Barometers, 2013

This is a behavioral health report for the United States. The report utilizes data from the National Survey on Drug Use and Health (NSDUH), the Youth and Risk Behavior Survey (YRBS), the Monitoring of the Future Survey sponsored by the National Institute on Drug Abuse and findings by the Center for Medicare & Medicaid Services about the use of of mental health and substance use treatment services by medicare recipients. The topics address in the report include youth substance use, youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment, and medicare enrollees for the years 2008 to 2012.
Compound 528314: Pyrazine, 3-ethoxy-2-octyl

Chemical compound data from PubChem database. IUPAC Name: 2-ethoxy-3-octylpyrazine. Molecular Formula: C14H24N2O. Molecular Weight: 236.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526598: 2,3,6-Tri-O-acetyl-1,5-Anhydro-4-O-methyl-D-glucitol

Chemical compound data from PubChem database. IUPAC Name: (4,5-diacetyloxy-3-methoxyoxan-2-yl)methyl acetate. Molecular Formula: C13H20O8. Molecular Weight: 304.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Arkansas (AR)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Arkansas overall and for substate regions within Arkansas. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Program Instruction (PI-10-06)

This Program Instruction (PI) provides instruction on the availability of Fiscal Year (FY) 2010 Funds under the Community-Based Grants for the Prevention of Child Abuse and Neglect program created by title II of the Child Abuse Prevention and Treatment Act as amended by Public Law (P.L.) 108-36.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 528585: tert-Butyl(dimethyl)silyl nonadecanoate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] nonadecanoate. Molecular Formula: C25H52O2Si. Molecular Weight: 412.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The estimated economic burden of genital herpes in the United States. An analysis using two costing approaches

Background
          Only limited data exist on the costs of genital herpes (GH) in the USA. We estimated the economic burden of GH in the USA using two different costing approaches.
        
        
          Methods
          The first approach was a cross-sectional survey of a sample of primary and secondary care physicians, analyzing health care resource utilization. The second approach was based on the analysis of a large administrative claims data set. Both approaches were used to generate the number of patients with symptomatic GH seeking medical treatment, the average medical expenditures and estimated national costs. Costs were valued from a societal and a third party payer's perspective in 1996 US dollars.
        
        
          Results
          In the cross-sectional study, based on an estimated 3.1 million symptomatic episodes per year in the USA, the annual direct medical costs were estimated at a maximum of $984 million. Of these costs, 49.7% were caused by drug expenditures, 47.7% by outpatient medical care and 2.6% by hospital costs. Indirect costs accounted for further $214 million. The analysis of 1,565 GH cases from the claims database yielded a minimum national estimate of $283 million direct medical costs.
        
        
          Conclusions
          GH appears to be an important public health problem from the health economic point of view. The observed difference in direct medical costs may be explained with the influence of compliance to treatment and possible undersampling of subpopulations in the claims data set. The present study demonstrates the validity of using different approaches in estimating the economic burden of a specific disease to the health care system.
Compound 528429: Propanol, 1(or 2)-(methyl-2-(methyl-2-propoxyethoxy)ethoxy)-

Chemical compound data from PubChem database. IUPAC Name: 1-[1-(1-propoxypropan-2-yloxy)propan-2-yloxy]propan-2-ol. Molecular Formula: C12H26O4. Molecular Weight: 234.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400318-T1: [Translated] AUTOMATIC CALIBRATION FOR RADIATION DOSIMETRY

Methods and devices for calibrating a radiotherapy system are disclosed. The method includes providing a detection medium that responds to exposure to ionizing radiation, and preparing a calibration dose response pattern by exposing predefined regions of the detection medium to different ionizing radiation dose levels. The method also includes measuring responses of the detection medium in the predefined regions to generate a calibration that relates subsequent responses to ionizing radiation dose. Different dose levels are obtained by differentially-shielding portions of the detection medium from the ionizing radiation using, for example, a multi-leaf collimator, a secondary collimator, or an attenuation block. Different dose levels can also be obtained by moving the detection medium between exposures. The disclosed device includes a software routine fixed on a computer-readable medium that is configured to generate a calibration that relates a response of a detection medium to ionizing radiation dose.
Elk Creek Seismic Waveforms 2012 (Part 15 of 20)

Coal bursts (damaging seismic events in underground coal mines) pose a substantial threat to operations and mine workers. The underground coal mines in Colorado’s North Fork Valley (NFV) have experienced many coal bursts, often with distinct characteristics from those of other US coal mining regions. To better understand these events and manage their associated risks, the National Institute for Occupational Safety and Health undertook a long-term monitoring campaign at the Elk Creek Mine in the NFV. The monitoring efforts included a seismic network composed of both surface and underground sensors, borehole pressure cells (BPCs), instrumented support Cans, convergence monitors, ground condition surveys, and several other data sources. This dataset consists of the event waveform files from the seismic network for the 983,379 events that were detected during the monitoring campaign. The waveforms are stored in HDF5 files that are broken up by week. Within the HDF5 files, the data are organized by station id, event time, and channel. The amplitudes are velocity in meters/second.
 
This is download 42 of 48 and corresponds to the time range between October 22, 2012, and October 29, 2012.
Compound 527014: N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)acetamide

Chemical compound data from PubChem database. IUPAC Name: N-(4-fluorophenyl)-N-[1-(2-phenylethyl)piperidin-4-yl]acetamide. Molecular Formula: C21H25FN2O. Molecular Weight: 340.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2012 Uniform Reporting System (URS) Tables for Northern Mariana Islands

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
2018-2020 NSDUH Substate Region Estimates Categorized Into Seven Groups, By Age Group

Substate estimates for these years are no longer available due to methodological concerns with combining 2020 data with data from 2018 and 2019. We apologize for any inconvenience or confusion this may cause.Because of the COVID-19 pandemic, most respondents answered the survey via the web in Quarter 4 of 2020, even though all responses in Quarter 1 were from in-person interviews. It is known that people may respond to the survey differently while taking it online, thus introducing what is called a mode effect.When the state estimates were released, it was assumed that the mode effect was similar for different groups of people. However, later analyses have shown that this assumption should not be made. Because of these analyses, along with concerns about the rapid societal changes in 2020, it was determined that averages across the three years could be misleading.For more detail on this decision, see the 2018-2020substate data page.
Compound 527096: Fluoxetine, N-acetyl

Chemical compound data from PubChem database. IUPAC Name: N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]acetamide. Molecular Formula: C19H20F3NO2. Molecular Weight: 351.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Drug Abuse Warning Network (DAWN): National Estimates from Drug-Related Emergency Department Visits, 2024

This report presents data on national estimates of substance-related ED visits from 60 participating DAWN hospitals in 2024. The data includes (1) all drug-related ED visits, (2) the top substances involved in drug-related ED visits, (3) opioid-related ED visits by type, and (4) polysubstance-related ED visits.
Increasing the satisfaction of general practitioners with continuing medical education programs: A method for quality improvement through increasing teacher-learner interaction

Background
          Continuing medical education (CME) for general practitioners relies on specialist-based teaching methods in many settings. Formal lectures by specialists may not meet the learning needs of practitioners and may cause dissatisfaction with traditional CME. Increasing learner involvement in teaching programs may improve learner satisfaction.
        
        
          Methods
          A quality improvement program for CME for 18 general practitioners in the Tel Aviv region was designed as a result of dissatisfaction with traditional CME activities. A two-step strategy for change was developed. The CME participants first selected the study topics relevant to them from a needs assessment and prepared background material on the topics. In the second step, specialist teachers were invited to answer questions arising from the preparation of selected topics. Satisfaction with the traditional lecture program and the new participatory program were assessed by a questionnaire. The quality criteria included the relevance, importance and applicability of the CME topic chosen to the participant's practice, the clarity of the presentation and the effective use of teaching aids by the lecturer and the potential of the lecturer to serve as a consultant to the participant.
        
        
          Results
          The participatory model of CME significantly increased satisfaction with relevance, applicability and interest in CME topics compared to the traditional lecture format.
        
        
          Conclusions
          Increased learner participation in the selection and preparation of CME topics, and increased interaction between CME teachers and learners results in increased satisfaction with teaching programs. Future study of the effect of this model on physician performance is required.
2013 CMHS Uniform Reporting System (URS) Tables for California

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for California for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Isolation,in silicocharacterization and chromosomal localization of a group of cDNAs from ciliated epithelial cells afterin vitrociliogenesis

Immotile cilia syndrome (ICS) or primary ciliary dyskinesia (PCD) is an autosomal recessive disorder in humans in which the beating of cilia and sperm flagella is impaired. Ciliated epithelial cell linings are present in many tissues. To understand ciliary assembly and motility, it is important to isolate those genes involved in the process.
Publications Using SAMHSA DataTreatment Episode Data Set (TEDS) 2000-2010 State Admissions to Substance Abuse Treatment Services

This is the Treatment Episode Data Set (TEDS) State Admissions to Substance Abuse Treatment Services report. This report presents data by Census division and State or jurisdiction for admissions in 2010 and trend data for 2000 to 2010. Demographic and substance abuse characteristics are reported for admissions to treatment aged 12 and older for abuse of alcohol and/or drugs in facilities that report to individual State administrative data systems.
Lantern Project

Lantern is an open source tool for monitoring fielded health IT systems' certified FHIR API endpoints. It gathers availability information and information about FHIR support from endpoints' capability statements and provides visualizations to show FHIR adoption and patient data availability across the nation. Lantern helps to ensure that patients will have digital access to their data by providing visibility into levels of FHIR adoption as well as FHIR endpoint availability and usability.
Compound 529656: Dimethyl 1,4a-dimethyl-8-methylenegibbane-1,10-dicarboxylate

Chemical compound data from PubChem database. IUPAC Name: dimethyl 4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylate. Molecular Formula: C22H32O4. Molecular Weight: 360.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528327: Furfuryl 2-methyl-2-propenyl sulfide

Chemical compound data from PubChem database. IUPAC Name: 1-(2-methylprop-2-enylsulfanylmethyl)cyclopenta-1,3-diene. Molecular Formula: C10H14S. Molecular Weight: 166.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Two novel frame shift, recurrent and

We have identified four different mutations causing leukocyte
adhesion deficiency (LAD) in the ITGB2 gene of patients from a highly inbred population. Two were novel single-bp deletions (1497delG and 1920delG) causing frame shift and the two others were the missense mutations G284S and R593C. In our study, the G284S was a recurrent mutation while the R593C occurred de novo. We have also characterized a novel Xba1 polymorphic site located at the 5′ end of the ITGB2 locus. Family studies showed that the 1497delG mutation segregated with this marker and the intragenic AvaII polymorphic marker, suggesting the presence of a founder effect. The observation of a
heterogeneous spectrum including de novo and recurrent mutations causing LAD in a highly inbred population is rather unexpected. In view of the literature published on the molecular genetics of LAD and considering the ethnic origin of the patients studied, our findings confirm the heterogeneity of the mutations causing LAD and point out potential mutational hot spots in the ITGB2 gene.
Patent AT-E401120-T1: [Translated] METHOD OF INCREASE TRANSMEMBRANE FLOW

The water flux of UF and MF membranes is dramatically increased by treatment with an aqueous solution of an organic linear polymer such as a polyglycol without detrimental decrease in other characteristics of the membrane, e.g. solute-rejection. Particular candidates for such treatment include UF and MF membranes made of PS, PES, PAN, and PVDF. The dramatic effectiveness of impregnation with aqueous solutions of PEG having molecular weights between about 2000 and 6000 Daltons is shown.
Collaborating Between Child Welfare and Mental Health

This Child Welfare Information Gateway Podcast is available on Apple Podcasts
  
  

, GooglePlay
  
  

, Spotify
  
  

, Stitcher
  
  

, SoundCloud
  
  

, and the Child Welfare Information Gateway
  
  

 website. Subscribe to receive new episodes as they are released.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 530514: 2-Chlorobenzoic acid, 4-hexadecyl ester

Chemical compound data from PubChem database. IUPAC Name: hexadecan-4-yl 2-chlorobenzoate. Molecular Formula: C23H37ClO2. Molecular Weight: 381.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526813: 14-Hydroxy-palmitic acid, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 14-[tert-butyl(dimethyl)silyl]oxyhexadecanoate. Molecular Formula: C23H48O3Si. Molecular Weight: 400.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E39969-T1: [Translated] BOREHOLE DRILLING DEVICE.

A well drilling assembly of the type in which a rotary device is attached to a drawworks, for example to the hoisting hook on a derrick, to which rotary device a hollow shaft (13) is coupled, having a threaded end which is adapted for connection to a complementary threaded end on the drill string, and wherein a clamping/lifting means known as an elevator (38) is suspended below the rotary device by two hanger struts (37). The shaft (13) connected to the rotary device is telescopic. Outside the shaft a lifting means (24, 25, 40) is provided for the lower part (21) of the telescopic shaft. The two hanger struts (37) which carry the elevator (38) for one end of the pipe are axially movable in relation to the telescopic shaft (13) by means of a sliding holder (35) known as a link hanger. The link hanger (35) is axially movable by means of hydraulic cylinders (42,43).The lifting means for the lower part of the telescopic shaft consists of hydraulic cylinders .(24, 25) which are constructed as a unit together with the hydraulic cylinders (42, 43), the cylinders (24, 25) constituting piston rods for the hydraulic cylinders (42,43).
Deaths by Race/Ethnicity and Resident County, New York State: Beginning 2018

This dataset contains the number of New York State deaths by race/ethnicity and resident county. The data presented here may differ from the Vital Statistics tables on the Department public website due to data updates. For more information, visit  https://www.health.ny.gov/statistics/vital_statistics/vs_reports_tables_list.htm,  where information from this dataset is presented in tabular form in Table 37.
Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes

Background
          Lysosomes are acidic organelles that play multiple roles in various cellular oxidative activities such as the oxidative burst during cytotoxic killing. It remains to be determined how lysosomal lumen oxidative activity and pH interact and are regulated. Here, I report the use of fluorescent probes to measure oxidative activity and pH of lysosomes in live macrophages upon treatment with the tumor promotor phorbol 12-myristate 13-acetate (PMA), and provide novel insight regarding the regulation of lysosomal oxidative activity and pH.
        
        
          Results
          The substrate used to measure oxidative activity was bovine serum albumin covalently coupled to dihydro-2', 4,5,6,7,7'-hexafluorofluorescein (OxyBURST Green H2HFF BSA). During pulse-chase procedures with live macrophages, this reduced dye was internalized via an endocytic pathway and accumulated in the lysosomes. Oxidation of this compound resulted in a dramatic increase of fluorescence intensity. By using low-light level fluorescence microscopy, I determined that phorbol ester treatment results in increased oxidative activity and pH elevation in different subsets of lysosomes. Furthermore, lysosomes with stronger oxidative activity tended to exclude the acidotropic lysosomal indicator, and thus exhibit higher alkalinity.
        
        
          Conclusions
          Results indicate that there is a regulatory mechanism between lysosomal oxidative activity and pH. Activation of lysosomal Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase by phorbol ester may result in increase of intralysosomal O2•- and H2O2, concurrent with pH elevation due to consumption of H+ and generation of OH-. Furthermore, the effect of phorbol ester on elevated oxidative activity and pH is heterogeneous among total lysosomal population. Higher oxidative activity and/or pH are only observed in subsets of lysosomes.
Compound 529234: tert-Butyl(dimethyl)(3-methylphenoxy)silane

Chemical compound data from PubChem database. IUPAC Name: tert-butyl-dimethyl-(3-methylphenoxy)silane. Molecular Formula: C13H22OSi. Molecular Weight: 222.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400776-T1: [Translated] OPERATING DEVICE FOR AN ELECTRICAL DEVICE

The device has an operating unit (11) with a rotary toggle (12) that is rotatable in an associated bearing (13), a signal arrangement for producing signals depending on a toggle position and/or change in position and controller for processing the signals to influence the electric equipment. The toggle can also be moved linearly in at least one direction and the signal arrangement can detect the linear movement (L).