AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 525672: p-Bromobenzylidene-octyl-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-octylmethanimine. Molecular Formula: C15H22BrN. Molecular Weight: 296.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527774: 2-Chloroethyl heptadecanoate

Chemical compound data from PubChem database. IUPAC Name: 2-chloroethyl heptadecanoate. Molecular Formula: C19H37ClO2. Molecular Weight: 332.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525889: N,N-Dimethyl-N'-(4-methoxyphenyl)-pivalamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-methoxyphenyl)-N,N,2,2-tetramethylpropanimidamide. Molecular Formula: C14H22N2O. Molecular Weight: 234.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525894: N,N-Dimethyl-N'-benzyl-isobutyramidine

Chemical compound data from PubChem database. IUPAC Name: N'-benzyl-N,N,2-trimethylpropanimidamide. Molecular Formula: C13H20N2. Molecular Weight: 204.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The NSDUH Report: Substance Use among Hispanic Adolescents

This report uses 2002 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past month alcohol use, cigarette use, marijuana use, and nonmedical use of prescription-type drugs among Hispanic youth aged 12 to 17. Results are shown for each substance by year, Hispanic subgroups, whether born in the U.S., gender, and, age group.
Giardiasis in children living in post-earthquake camps from Armenia (Colombia)

Background
          An earthquake in the coffee growing region of Colombia on January 25, 1999 destroyed 70% of the houses in Armenia city. Transitory housing camps still remained until two years after the disaster. Parasitological studies found that, in this population, giardiasis was the most frequent parasitic infection. This study was carried out in order to determine the epidemiological risk factors associated with this high prevalence.
        
        
          Methods
          Fecal samples were obtained from 217 children aged between 3 and 13 years. Stool samples were studied by direct wet examination and stained with ferric hematoxilin for microscopical examination. Epidemiological data were collected by questionnaire and analyzed by using the Epi-info software (CDC, Atlanta 2001).
        
        
          Results
          Giardia cysts were observed in 60.4% of the samples presented and trophozoites in 4.6%. The following epidemiological and laboratory factors were significantly associated with Giardia infection: 1. Use of communal toilet (vs. individual toilet) OR: 3.9, CI95%: 1.2–16; 2. water provision by municipal ducts (vs. water provision by individual tanks) OR: 3.5, CI95% 1.1–14, and 3. presence of mucus in stool OR: 2.3, IC95%: 0.9–6.7.
        
        
          Conclusions
          A high prevalence of giardiasis was found in children living in temporary houses after the 1999 earthquake in Armenia (Colombia). Giardiasis is an emerging disease in post-disaster situations and adequate prevention measures should be implemented during these circumstances.
Myelin contributes to the parallel orientation of axonal growth on white matter

Background
          Brain and spinal cord white matter can support extensive axonal growth. This growth is generally constrained to an orientation that is parallel to the longitudinal axis of the fiber tract. This constraint is presumably due to permissive and non-permissive substrates that are interleaved with each other and oriented in parallel within the tract.
        
        
          Results
          Embryonic chick sympathetic neurons were cultured on cryostat sections of rat brain and the orientation of neurite growth on white matter was assessed. To determine if haptotaxis is sufficient to guide parallel neurite growth, neurons were cultured under conditions designed to interfere with interactions between growing neurites and factors that act as biochemical contact guidance cues but not interactions with haptotactic cues. Under these conditions, neurites extending on white matter were not exclusively oriented in parallel to the fiber tract, suggesting that biochemical cues are involved. To assess the role of myelin in guiding parallel neurite growth, neurons were cultured on myelin-deficient corpus callosum. These neurons also extended neurites that were not constrained to a parallel orientation. Moreover, preincubation with NGF and treatment with cAMP analogs, manipulations that attenuate overall myelin-mediated inhibition of neurite growth, also led to a reduced parallel orientation of neurite growth.
        
        
          Conclusions
          The present studies suggest that some of the relevant factors that constrain axonal growth on white matter are not haptotactic in nature and appear to be partly mediated by factors that are associated with myelin and may involve myelin-associated "inhibitors".
Substance Use and Mental Disorders in Metropolitan Areas: Results From the 2005-2010 National Survey on Drug Use and Health

This page presents the metro reports from the combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) and the data tables that show results for all metro areas. The metro reports include estimates of rates substance use and mental disorders in the United States and in 33 metropolitan areas across nation. Topics covered include substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided by metro area, state, and the U.S. overall.
Antithrombin III in patients admitted to intensive care units: a multicenter observational study

Introduction
          The administration of antithrombin III (ATIII) is useful in patients with congenital deficiency, but evidence for the other therapeutic indications of this drug is still uncertain. In Italy, the use of ATIII is very common in intensive care units (ICUs). For this reason we undertook an observational study to determine the pattern of use of ATIII in ICUs and to assess the outcome of patients given this treatment.
        
        
          Methods
          From 20 May to 20 July 2001 all consecutive patients admitted to ICUs in 20 Italian hospitals and treated with ATIII were enrolled. The following information was recorded from each patient: congenital deficiency, indication for use of ATIII, daily dose and duration of ATIII treatment, outcome of hospitalization (alive or dead). The outcome data of our observational study were compared with those reported in previously published randomized controlled trials (RCTs).
        
        
          Results
          Two hundred and sixteen patients were enrolled in the study. The clinical indications for using ATIII were sepsis (25.9%), disseminated intravascular coagulation (23.1%), and other clinical conditions (46.8%). At the end of the study, 65.3% of the patients were alive, 24.5% died and 10.2% were still in the hospital. Among the patients with sepsis (n = 56), 19 died during the observation period (33.9%; 95% confidence interval 22.1–47.5%).
        
        
          Discussion
          Our study described the pattern of use of ATIII in Italian hospitals and provided information on the outcome of the subgroup treated with sepsis. A meta-analysis of current data from RCTs, together with our findings, indicates that there is no sound basis for using this drug in ICU patients with sepsis.
Compound 525277: N'-Butyl-N,N-dimethyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N'-butyl-N,N-dimethylethanimidamide. Molecular Formula: C8H18N2. Molecular Weight: 142.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401583-T1: [Translated] IN-SITU METHOD FOR DETERMINING EARTH LIQUIDATION TENDENCY AND ITS PREVENTION BY ELECTROOSMOSIS

A method for determining the liquefaction tendency of a water saturated soil is provided in which a driven or self boring probe with a plurality of expanding and contracting bladders imposes a cyclic shear stress reversal on a body of soil in situ, and from the measurement of pore water pressure, the liquefaction potential of the soil can be quantified. A pore water pressure increase during cyclic shear stress reversals indicates a contractive soil which has the potential to liquefy. The method can also quantify the potential of electro-osmosis in preventing soil liquefaction, by energizing a group of at least three electrodes by a d-c power source during the potential onset of liquefaction, and measure the reduction in pore water pressure during subsequent repeated shear stress reversals imposed on the soil by the device.
Impaired Driving Death Rate, by Age and Sex, 2012 & 2014, Region 3 - Philadelphia

Rate of deaths by age/gender (per 100,000 population) for people killed in crashes involving a driver with BAC =>0.08%, 2012, 2014. 2012 Source: Fatality Analysis Reporting System (FARS). 2014 Source: National Highway Traffic Administration's (NHTSA) Fatality Analysis Reporting System (FARS), 2014 Annual Report File. Note: Blank cells indicate data are suppressed. Fatality rates based on fewer than 20 deaths are suppressed.
Changes in anti-viral effectiveness of interferon after dose reduction in chronic hepatitis c patients: a case control study

Background
          High dose interferon induction treatment of hepatitis C viral infection blocks viral production over 95%. Since dose reduction is often performed due to clinical considerations, the effect of dose reduction on hepatitis C virus kinetics was studied.
        
        
          Methods
          A new model that allowed longitudinal changes in the parameters of viral dynamics was used in a group of genotype-1 patients (N = 15) with dose reduction from 10 to 3 million units of interferon daily in combination with ribavirin, in comparison to a control group (N = 9) with no dose reduction.
        
        
          Results
          Dose reduction gave rise to a complex viral kinetic pattern, which could be only explained by a decrease in interferon effectiveness in blocking virion production. The benefit of the rapid initial viral decline following the high induction dose is lost after dose reduction. In addition, in some patients also the second phase viral decline slope, which is highly predictive of success of treatment, was impaired by the dose reduction resulting in smaller percentage of viral clearance in the dose reduction group.
        
        
          Conclusions
          These findings, while explaining the failure of many induction schedules, suggest that for genotype-1 patients induction therapy should be continued till HCVRNA negativity in serum in order to increase the sustained response rate for chronic hepatitis C.
Compound 526889: Triethylene glycol, pentyl ether, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-[2-(2-pentoxyethoxy)ethoxy]ethoxy]silane. Molecular Formula: C14H32O4Si. Molecular Weight: 292.49. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table II. Ehrlichiosis/Anaplasmosis

NNDSS - Table II. Ehrlichiosis/Anaplasmosis - 2014.In this Table, all conditions with a 5-year average annual national total of more than or equals 1,000 cases but less than or equals 10,000 cases will be displayed (��� 1,000 and ��_ 10,000). The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories. Note:These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. Footnotes:C.N.M.I.: Commonwealth of Northern Mariana Islands. U: Unavailable.    -: No reported cases.    N: Not reportable.    NN: Not Nationally Notifiable    Cum: Cumulative year-to-date counts.    Med: Median.    Max: Maximum. * Case counts for reporting years 2013 and 2014 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for TB are displayed in Table IV, which appears quarterly. ��� Please refer to the MMWR publication for weekly updates to the footnote for this condition.More information on NNDSS is available at http://wwwn.cdc.gov/nndss/.
Compound 530654: o-Toluic acid, hex-4-yn-3-yl ester

Chemical compound data from PubChem database. IUPAC Name: hex-4-yn-3-yl 2-methylbenzoate. Molecular Formula: C14H16O2. Molecular Weight: 216.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400673-T1: [Translated] PRODUCING A HIGH DENSITY THICK CERAMIC FILM BY SCREEN PRINTING

A high density ceramic thick film is fabricated by providing vehicle comprising an organic binder and solvent, dispersing ceramic powders into the vehicle to be paste, forming the paste to thick film by screen printing, removing the organic binder from the film, applying sol or sol-like solution to the surface of the film so that the sol or sol-like solution can infiltrate into the film, removing remaining sol or sol-like solution from the surface of the film, drying and preheating the film, and sintering the film.
Compound 528974: 1,2-Eicosanediol, di-TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(1-trimethylsilyloxyicosan-2-yloxy)silane. Molecular Formula: C26H58O2Si2. Molecular Weight: 458.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Table 16. Perceptions of Great Risk of Smoking One or More Packs of Cigarettes per Day among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 16. Perceptions of Great Risk of Smoking One or More Packs of Cigarettes per Day among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Patent AT-E401511-T1: [Translated] UNIVERSAL JOINT ARRANGEMENT

The arrangement has a cross pivot (3) supported in two articular shanks (6). Each shank has bearing parts (8, 9), where each part has a bearing hole in which pivots (4, 5) of the cross pivot are supported. Each pivot is supported by a bearing arrangement (10) that has an axial bearing supported directly or indirectly by a partially flexible spring unit (2). The unit is characterized by sections, which are arranged adjacent to each other in circumferential direction and are made from different materials and material combinations, where the materials differ with respect to their elastic modulus.
Compound 525621: N,N-Dimethyl-N'-cyclohexyl-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-cyclohexyl-N,N,4-trimethylbenzenecarboximidamide. Molecular Formula: C16H24N2. Molecular Weight: 244.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
CalYOUTH: Proving Extended Foster Care Works for Young Adults in Transition from Foster Care

Since October 1, 2010, title IV-E agencies have the option to provide extended foster care up to age 21. The state of California was an early adopter of this option and also funded the collection of data, research, and an evaluation to understand the implementation and outcomes.

Learn how the state of California has designed and implemented an extended foster care program that improves the lives of young people in transition from foster care.

Presenters:

Co-Hosts:

Audio Description Version

Metadata-only record linking to the original dataset. Open original dataset below.
Rilonacept

Arcalyst (rilonacept) is a prescription medication manufactured by Kiniksa Pharmaceuticals (UK), Ltd., used to treat certain autoinflammatory conditions. It comes as a lyophilized powder in single-use vials for subcutaneous injection, with each vial containing 160 mg of rilonacept in 2 mL after reconstitution. This information was generated using AI and is provided for informational and research purposes only.
Influenza Laboratory-Confirmed Cases by County: Beginning 2009-10 Season

This dataset includes weekly counts of laboratory-confirmed influenza (flu) cases, by county and influenza type, going back to the 2009-10 season. The primary goal of this dataset is to provide users timely information about local influenza activity throughout the current influenza season. Although each influenza season is unique, historical data is also provided for trend comparison. In view of persisting elevated influenza activity throughout NYS, NYSDOH is extending the surveillance 2021-2022 season beyond May until influenza activity has decreased. <b>In view of persisting elevated influenza activity throughout NYS, NYSDOH is extending the surveillance season beyond May until influenza activity has decreased.</b>

Cases are included that meet the New York State Department of Health’s (NYSDOH) standardized case definition, i.e., a positive result on any of the following influenza laboratory tests:
•	Rapid Influenza Diagnostic Tests (RIDT)
•	Immunofluorescence assays (DFA and IFA)
•	Rapid Molecular Assays
•	Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
•	Other Nucleic Acid Amplification tests
•	Viral Culture
Please see the overview document for more details about NYSDOH’s influenza case definition. Cases reported during the CDC-defined influenza surveillance season (week 40-week 20 of the next calendar year; October through mid-May) are included. For more information see: http://www.health.ny.gov/diseases/communicable/influenza/surveillance/.
Compound 529352: 4-Acetyl-2-isopropenylpyridine

Chemical compound data from PubChem database. IUPAC Name: 1-(2-prop-1-en-2-ylpyridin-4-yl)ethanone. Molecular Formula: C10H11NO. Molecular Weight: 161.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays

Background
          Gene targeting would offer a number of advantages over current transposon-based strategies for insect transformation. These include freedom from both position effects associated with quasi-random integration and concerns over transgene instability mediated by endogenous transposases, independence from phylogenetic restrictions on transposon mobility and the ability to generate gene knockouts.
        
        
          Results
          We describe here our initial investigations of gene targeting in the mosquito. The target site was a hygromycin resistance gene, stably maintained as part of an extrachromosomal array. Using a promoter-trap strategy to enrich for targeted events, a neomycin resistance gene was integrated into the target site. This resulted in knockout of hygromycin resistance concurrent with the expression of high levels of neomycin resistance from the resident promoter. PCR amplification of the targeted site generated a product that was specific to the targeted cell line and consistent with precise integration of the neomycin resistance gene into the 5' end of the hygromycin resistance gene. Sequencing of the PCR product and Southern analysis of cellular DNA subsequently confirmed this molecular structure.
        
        
          Conclusions
          These experiments provide the first demonstration of gene targeting in mosquito tissue and show that mosquito cells possess the necessary machinery to bring about precise integration of exogenous sequences through homologous recombination. Further development of these procedures and their extension to chromosomally located targets hold much promise for the exploitation of gene targeting in a wide range of medically and economically important insect species.
Elevated antibody to D-alanyl lipoteichoic acid indicates caries experience associated with fluoride and gingival health

Background
          Acidogenic, acid-tolerant bacteria induce dental caries and require D-alanyl glycerol lipoteichoic acid (D-alanyl LTA) on their cell surface. Because fluoride inhibits acid-mediated enamel demineralization, an elevated antibody response to D-alanyl LTA may indicate subjects with more acidogenic bacteria and, therefore, an association of DMFT with fluoride exposure and gingival health not apparent in low responders.
        
        
          Methods
          Cluster analysis was used to identify low antibody content. Within low and high responders (control and test subjects), the number of teeth that were decayed missing and filled (DMFT), or decayed only (DT) were regressed against fluoride exposure in the water supply and from dentrifice use. The latter was determined from gingival health: prevalences of plaque (PL) and bleeding on probing (BOP), and mean pocket depth (PD). Age was measured as a possible confounding cofactor.
        
        
          Results
          In 35 high responders, DMFT associated with length of exposure to fluoridated water (F score), PL and BOP (R2 = 0.51, p < 0.001), whereas in 67 low D-ala-IgG responders, DMFT associated with PL, age, and PD (R2 = 0.26, p < 0.001). BOP correlated strongly with number of 7 7 decayed teeth (DT) in 54 high responders (R2 = 0.57, p < 0.001), but poorly in 97 low responders (R2 = 0.12, p < 0.001). The strength of the PD association with DMFT, or of BOP with DT, in high responders significantly differed from that in low responders (p < 0.05).
        
        
          Conclusion
          Caries associates with gingival health and fluoridated water exposure in high D-alanyl LTA antibody responders.
Compound 530090: 2-Hydroxypurine, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl-(2-trimethylsilyloxypurin-7-yl)silane. Molecular Formula: C11H20N4OSi2. Molecular Weight: 280.47. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.