AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 526512: 2-Isothiocyanato-hexanoic acid ethyl ester

Chemical compound data from PubChem database. IUPAC Name: ethyl 2-isothiocyanatohexanoate. Molecular Formula: C9H15NO2S. Molecular Weight: 201.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Signal analysis of behavioral and molecular cycles

Background
          Circadian clocks are biological oscillators that regulate molecular, physiological, and behavioral rhythms in a wide variety of organisms. While behavioral rhythms are typically monitored over many cycles, a similar approach to molecular rhythms was not possible until recently; the advent of real-time analysis using transgenic reporters now permits the observations of molecular rhythms over many cycles as well. This development suggests that new details about the relationship between molecular and behavioral rhythms may be revealed. Even so, behavioral and molecular rhythmicity have been analyzed using different methods, making such comparisons difficult to achieve. To address this shortcoming, among others, we developed a set of integrated analytical tools to unify the analysis of biological rhythms across modalities.
        
        
          Results
          We demonstrate an adaptation of digital signal analysis that allows similar treatment of both behavioral and molecular data from our studies of Drosophila. For both types of data, we apply digital filters to extract and clarify details of interest; we employ methods of autocorrelation and spectral analysis to assess rhythmicity and estimate the period; we evaluate phase shifts using crosscorrelation; and we use circular statistics to extract information about phase.
        
        
          Conclusion
          Using data generated by our investigation of rhythms in Drosophila we demonstrate how a unique aggregation of analytical tools may be used to analyze and compare behavioral and molecular rhythms. These methods are shown to be versatile and will also be adaptable to further experiments, owing in part to the non-proprietary nature of the code we have developed.
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures

Background
          Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report we describe the binding properties of purified Autographa californica multiple capsid nucleopolyhedrovirus (AcMNPV) VLF-1 to a number of different DNA structures including homologous regions. In addition, its enzymatic activity was examined.
        
        
          Results
          VLF-1 was expressed in a recombinant baculovirus as a fusion with both HA and HIS6 tags and its binding activity to different DNA structures was tested. No binding was evident to single and double strand structures, very low binding was observed to Y-forks, more binding was observed to three-way junctions, whereas cruciform structures showed high levels of binding. VLF-1 binding was affected by divalent cations; optimal binding to three-way junctions and cruciforms was 2 and 0 mM MgCl2, respectively. Homologous region (hr) sequences was also examined including oligomers designed to expose the hr palindrome as a hairpin, linear double strand, or H-shaped structure. Efficient binding was observed to the hairpin and H-shaped structure. No topoisomerase or endonuclease activity was detected. Sedimentation analysis indicated that *VLF-1 is present as a monomer.
        
        
          Conclusions
          An HA- and HIS-tagged version of AcMNPV VLF-1 showed structure-dependent binding to DNA substrates with the highest binding affinity to cruciform DNA. These results are consistent with the involvement of VLF-1 in the processing of branched DNA molecules at the late stages of viral genome replication. We were unable to detect enzymatic activity associated with these complexes.
NorWeST Observed Stream Temperature Points (Feature Layer)

This layer indicates the location of the observed stream temperature records used for the NorWeST database summaries. NorWeST summer stream temperature scenarios were developed for all rivers and streams in the western U.S. from the greater than 20,000 stream sites in the NorWeST database where mean August stream temperatures were recorded. The resulting dataset includes stream lines (NorWeST_PredictedStreams) and associated mid-points NorWest_TemperaturePoints) representing 1 kilometer intervals along the stream network. Stream lines were derived from the 1:100,000 scale NHDPlus dataset (USEPA and USGS 2010; McKay et al. 2012). Shapefile extents correspond to NorWeST processing units, which generally relate to 6 digit (3rd code) hydrologic unit codes (HUCs) or in some instances closely correspond to state borders. The line and point shapefiles contain identical modeled stream temperature results. The two feature classes are meant to complement one another for use in different applications. In addition, spatial and temporal covariates used to generate the modeled temperatures are included in the attribute tables at https://www.fs.usda.gov/rm/boise/AWAE/projects/NorWeST/ModeledStreamTemperatureScenarioMaps.shtml. The NorWeST NHDPlusV1 processing units include: Salmon, Clearwater, Spokoot, Missouri Headwaters, Snake-Bear, MidSnake, MidColumbia, Oregon Coast, South-Central Oregon, Upper Columbia-Yakima, Washington Coast, Upper Yellowstone-Bighorn, Upper Missouri-Marias, and Upper Green-North Platte. The NorWeST NHDPlusV2 processing units include: Lahontan Basin, Northern California-Coastal Klamath, Utah, Coastal California, Central California, Colorado, New Mexico, Arizona, and Black Hills.
Pharmacogenetics, pharmacogenomics and airway disease

The availability of a draft sequence for the human genome will revolutionise research into airway disease. This review deals with two of the most important areas impinging on the treatment of patients: pharmacogenetics and pharmacogenomics. Considerable inter-individual variation exists at the DNA level in targets for medication, and variability in response to treatment may, in part, be determined by this genetic variation. Increased knowledge about the human genome might also permit the identification of novel therapeutic targets by expression profiling at the RNA (genomics) or protein (proteomics) level. This review describes recent advances in pharmacogenetics and pharmacogenomics with regard to airway disease.
Elk Creek Seismic Waveforms 2012 (Part 11 of 20)

Coal bursts (damaging seismic events in underground coal mines) pose a substantial threat to operations and mine workers. The underground coal mines in Colorado’s North Fork Valley (NFV) have experienced many coal bursts, often with distinct characteristics from those of other US coal mining regions. To better understand these events and manage their associated risks, the National Institute for Occupational Safety and Health undertook a long-term monitoring campaign at the Elk Creek Mine in the NFV. The monitoring efforts included a seismic network composed of both surface and underground sensors, borehole pressure cells (BPCs), instrumented support Cans, convergence monitors, ground condition surveys, and several other data sources. This dataset consists of the event waveform files from the seismic network for the 983,379 events that were detected during the monitoring campaign. The waveforms are stored in HDF5 files that are broken up by week. Within the HDF5 files, the data are organized by station id, event time, and channel. The amplitudes are velocity in meters/second.
 
This is download 38 of 48 and corresponds to the time range between September 3, 2012, and October 1, 2012.
Patent AT-E399859-T1: [Translated] ANTI-APOPTOTIC APATAMERS

The invention relates to anti-apoptotically active apatamers. The invention describes possible therapeutic and diagnostic applications for, among other things, treating arteriosclerosis, promoting the healing of wounds, treating AIDS, cancer, Alzheimer's disease, systemic lupus erythematosus as well a rheumatoid arthritis and other chronic inflammatory diseases.
Managed Care Institutional Provider Network Data: March 31, 2013

The primary purpose for the Provider Network Data System is to collect data needed to evaluate the provider networks including physicians, hospitals, labs, home health agencies, durable medical equipment providers, etc., for all types of Managed Care plans in New York State, including HIV Special Need Plans (SNP), Family Health Plus (FHP) Buy-In, Programs of All-Inclusive Care for the Elderly (PACE), and Non-PACE Managed Long-Term Care (MLTC) plans. This dataset reflects institutional provider data. Provider Network Data System information is self reported. For more information, go to http://www.health.ny.gov/health_care/managed_care/.
Table 17. 2011-2012 NSDUH Alcohol Dependence in the Past Year, by Age Group and State

Table 17. Alcohol Dependence in the Past Year, by Age Group and State: Percentages, Annual Averages Based on 2011 and 2012 NSDUHs. Results are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Publications Using SAMHSA DataState Estimates of Adolescent Cigarette Use and  Perceptions of Risk of Smoking: 2012 and 2013

This short report uses 2012 to 2013 National Survey on Drug Use and Health (NSDUH) to assess cigarette risk perception and cigarette use among adolescents aged 12 to 17 by State. Results are shown by State for 2002-2003 and 2012-2013.
Compound 527818: 4-(Cyclohexyloxy)-benzeneacetic acid

Chemical compound data from PubChem database. IUPAC Name: 2-(4-cyclohexyloxyphenyl)acetic acid. Molecular Formula: C14H18O3. Molecular Weight: 234.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527329: Oxphenbutazone di-methyl derivative

Chemical compound data from PubChem database. IUPAC Name: 4-butyl-5-methoxy-1-(4-methoxyphenyl)-2-phenylpyrazol-3-one. Molecular Formula: C21H24N2O3. Molecular Weight: 352.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530463: o-Toluic acid, 2-adamantyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-adamantyl 2-methylbenzoate. Molecular Formula: C18H22O2. Molecular Weight: 270.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Monthly Variation in Substance Use Initiation Among Full-Time College Students

This report uses combined 2002 to 2013 National Survey on Drug Use and Health (NSDUH) to assess the average number of full-time college students aged 18 to 22 using substances for the first time per day for the year as a whole and for each month of the year. Substances examined include alcohol, cigarettes, cigars, marijuana, nonmedical use of prescription pain relievers, nonmedical use of prescription tranquilizers, nonmedical use of prescription stimulants, nonmedical use of prescription sedatives, inhalants, hallucinogens, and cocaine. Results are shown for each substance by month.
Refugee Arrival Data

Oversees refugee arrival data for 2012-2015 fiscal years. Counts of served peoples' country of origin (columns) and state of resettlement (rows) for each fiscal year.

<b>Units of Response: </b>Refugee

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>No

<b>Periodicity: </b>Annual

<b>Demographic Indicators: </b>Unavailable

<b>SORN: </b>https://www.federalregister.gov/documents/2015/04/02/2015-07440/privacy-act-of-1974-system-of-records-notice

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Not Applicable

<b>Granularity: </b>State

<b>Spatial: </b>United States

<b>Geocoding: </b>State
Compound 529476: N-(1-Naphthyl)-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxamide

Chemical compound data from PubChem database. IUPAC Name: [3,5-bis(trimethylsilyloxy)oxan-4-yl]oxy-trimethylsilane. Molecular Formula: C14H34O4Si3. Molecular Weight: 350.67. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401451-T1: [Translated] METHOD FOR TREATING A WEB, PARTICULARLY A PAPER WEB

In a paper manufacturing process a web (11) of paper or carton feeds between a lower shoe drum (2) with a flexible mantle (5) and a heated overhead drum (3). The two drums form a broad nip (4) between their two faces. The mantle (5) is continually monitored for signs of damage that would indicate the onset of fire. If fire is detected the drums are separated and the web continues through the nip as a fire blanket. Mantle damage is detected by monitoring a change in pressure within a void (8) surrounded by the mantle. The shoe drum is monitored by an optical device e.g. a camera. In the event of a web break the web winds itself around either the top or bottom drum behind the wide nip. The rolled-up web is detached from the drum when the accumulated paper reaches a pre-determined thickness on the drum.
2020 National Mental Health Services Survey (N-MHSS) Annual Report

This report presents findings from the 2020 National Mental Health Services Survey (N-MHSS), an annual census of all known facilities in the United States, both public and private, that provide mental health treatment services to people with mental illness. Planned and directed by the Center for Behavioral Health Statistics and Quality (CBHSQ) of the Substance Abuse and Mental Health Services Administration (SAMHSA), U.S. Department of Health and Human Services, the N-MHSS is designed to collect data on the location, characteristics, and utilization of organized mental health treatment services for facilities within the scope of the survey throughout the 50 states, the District of Columbia, Puerto Rico, and other jurisdictions.
Patent AT-E39979-T1: [Translated] CONNECTING THE ENDS OF CONVEYOR BELTS.

1. A connection of the ends of conveyor belts with elastomeric material into which are embedded at least one layer of longitudinal filaments which extend substantially in the running direction of the conveyor belt and at least one layer comprising transverse filaments which extend at an angle of inclination of in particular 90 degrees to the running direction and where, in the region of the connection, the ends of at least one layer are finger-shaped and interlock with one another, characterised in that the longitudinal filaments are arranged as tension carriers (2) in a single tension carrier layer which is separated from the layer comprising the transverse filaments by at least one elastomeric intermediate layer (4) and that the transverse filaments consist of entwined and/or twisted individual filaments or fibres which are arranged at an angle of inclination of at least 45 degrees to the running direction, are combined by means of a hardened bonding agent to form stiff cords (8), and stiffen the layer in question to form a stiffening layer (7).
Patent AT-E400640-T1: [Translated] PERFUMED DETERGENT MOLDS

A perfumed single- or multi-phase detergent body is obtained by contacting a shaped body based on surfactant(s), builder(s) and conventional additives with one or more perfumes or an active mixture containing at least20 wt.% perfume based on the shaped body wt.  An Independent claim is also included for the use of a mixture containing polyalkyleneglycol(s) and perfume as an adhesive in the detergent.
Patent AT-E400898-T1: [Translated] SOLAR CELL WITH INTEGRATED PROTECTION DIODE

The invention relates to a solar cell which comprises photoactive semiconductor layers extending between the front and the back contact, and an integrated protective diode (bypass diode), said protective diode having a polarity opposite to that of the solar cell and is provided at its front with a p-conducting semiconductor layer, and the protective diode is connected to the front contact. The aim of the invention is to provide a highly stable protective diode and to prevent a migration of metal atoms. For this purpose, a tunnel diode (38) extends on the p-conducting semiconductor layer (36) of the protective diode (32), said tunnel diode being connected to the front contact (14) via an n+ layer.
Research Article: BMC Gastroenterology

Background
          The cytotoxin associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) of Helicobacter pylori have been associated to phenotypic characteristics of virulence. The objectives of this study were to detect the presence of cagA and to characterize the allelic variants of vacA in 63 strains of H. pylori isolated from colonized individuals with different clinical outcomes.
        
        
          Methods
          38 strains were isolated from patients with non-ulcerative dyspepsia (NUD) and 25 were isolated from colonized individuals with peptic ulcers. The genotypic characterization was carried out utilizing PCR methodology. The presence of the cagA gene was detected using two set of primers from the middle conservative region of the cagA, and primers for the signal and middle region were used for the genotyping of vacA
        
        
          Results
          The presence of cagA showed similar rates in strains from peptic ulcers (60%) and NUD patients (55%). Also similar was the prevalence of the allelic form s1 of vacA between the strains obtained from ulcers or NUD patients. However, the combination cagA+/vacA s1m1 was found more frequently among the H. pylori strains from peptic ulcer patients (52%) than among strains isolated from NUD patients (26%), this difference was statistically significant (p = 0.035).
        
        
          Conclusions
          The presence of either cagA or the allelic variant s1 vacA alone do not have a predictive value as as a risk markers of severe gastric pathologies in the Chilean population. However, being infected by a H. pylori strain with the genotype cagA+/vacA s1m1 may be associated to an increased risk of acquiring a peptic ulcer disease.
Patent AT-E401542-T1: [Translated] DEVICE FOR DISTRIBUTING BULK GOODS INTO AT LEAST TWO BUNKERS LOCATED ABOVE THE GUT OF A BLASTIC FURNACE

Device for distributing bulky material into bunkers (12', 12'') arranged above the mouth (11) of a blast furnace comprises a bulky material reversing flap (33) assigned to inlet openings (31, 32) to open and close the openings. When the inlet opening (32) is open, the other inlet opening (31) is closed and vice versa.
Information on the Children's Bureau Discretionary Grants

This webpage provides general information about Children's Bureau discretionary grants.

Forecasts - As it becomes available, information about planned funding opportunity announcements is available on the Department of Health and Human Services Grants Forecast website
  
  

. To find the Children's Bureau's planned announcements, select "ACF (Administration on Children and Families)" in the “Agency” field.

Publication dates - Several separate Children's Bureau funding opportunity announcements are published each year, rather than one consolidated announcement. They are usually published at different times.

Publication sites - Children's Bureau discretionary grant funding opportunity announcements are published in Grants.gov
  
  

, and on the ACF Funding Opportunity Announcement page.

Grants.gov - Grants.gov is the single location for all Federal grant program information.  A short synopsis of each funding opportunity announcement is posted here as soon as it is released for publication. In Grants.gov, the Children's Bureau's funding opportunity announcements are listed under the Funding Activity Category Income Security and Social Services, and under the Agency Category Department of Health and Human Services. Grants.gov provides customer support via e-mail and telephone.

Notification of publication - Visit Grants.gov and the ACF grants opportunity page to access publication information. The Grants.gov web site has options for requesting automated notification. In Grants.gov you can select categories of funding opportunity announcements, and ask to be notified when these announcements are published.

Getting an application - After an announcement is published, applicants can download the announcement and required forms. The announcement will include all the information needed to complete and submit your application.

Electronic Submission - Applicants must submit their application electronically, unless they request and are granted a waiver. Applicants are advised to be sure that they secure and retain their service ticket number for reference whenever they have any interaction with the Grants.gov Contact Center. Electronic applications will be accepted only through Grants.gov. Detailed instructions for applying on-line are posted on Grants.gov. Grants.gov provides customer support via email and telephone.

For further questions - Please call the CB Operations Center at 1-866-796-1591.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525430: 3,3-Dimethyl-4-thiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-propylsulfanylbutane. Molecular Formula: C8H18S. Molecular Weight: 146.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527369: 18,22-Dimethyl-tritriacontyl cyanide

Chemical compound data from PubChem database. IUPAC Name: 19,23-dimethyltetratriacontanenitrile. Molecular Formula: C36H71N. Molecular Weight: 518.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.