AndreaBozzo/ceres-open-data-index huggingface dataset:
Diagnostic criteria for diabetes revisited: making use of combined criteria

Background
          Existing cut-offs for fasting plasma glucose (FPG) and post-load glucose (2hPG) criteria are not equivalent in the diagnosis of diabetes and glucose intolerance. Adjusting cut-offs of single measurements have not helped so we undertook this project to see if they could be complementary.
        
        
          Methods
          We performed oral glucose tolerance tests and mean levels of hemoglobin A1c (HbA1c) measurements on 43 patients referred to a diabetes clinic for possible diabetes. Results of single and combined use of the FPG and 2hPG criteria were evaluated against the levels of HbA1c and results re-interpreted in the light of existing reports in the literature.
        
        
          Results
          Our results confirm that the FPG and the 2hPG, being specific and sensitive respectively for the presence of glucose intolerance or diabetes, are not equivalent. They are shown to be indeed complementary and a re-definition of diagnostic criteria based on their combined use is proposed.
        
        
          Conclusions
          We conclude that altering single measurement cut-offs for the diagnosis of diabetes and altered glucose tolerance will not result in better outcomes. We present the case for a combined criteria in the diagnosis and definition of diabetes with a FPG≥7 mmol/L AND 2-hour glucose ≥7.8 mmol/L being used to define diabetes while a FPG<7 mmol/L AND 2-hour glucose <7.8 mmol/L being used to define normality. Discordant values will define impaired glucose tolerance (IGT). This proposal requires prospective evaluation in a large cohort.
2014 CMHS Uniform Reporting System (URS) Table for Connecticut

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Connecticut. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Nursing Home Profiles Quality Data: Beginning 2020

The Nursing Homes Profiles quality data provides a consumer-friendly product that allows patients and their families to understand how the New York State Nursing Homes perform within five specific domains of care and overall. The domains (Preventive Care, Quality of Care, Quality of Life, Resident Safety and Resident Status) encompass twenty-four different quality measures. A Domain Rating assesses performance over all the measures within that domain, with 5 stars indicating the highest performance and 1 star the lowest performance.  The Overall Rating is a normalized star rating based on the Nursing Homes' performance across the five domains. The normalization of the Overall Rating resets the distribution, with the highest performing Nursing Homes across all the domains having 5 stars and the lowest performing Nursing Homes across the five domains having 1 star. New York’s Nursing Home Domain Rating differs from CMS’ 5-star rating in data reporting period and in methodology.
Patent AT-E400997-T1: [Translated] APPARATUS AND METHOD FOR DRIVING ANIMALS IN AN ELONGATED CORRIDOR SECTION

Device for driving animals in an oblong corridor section using a driving gate which can be moved from one end to the other of the corridor section. A first transport arrangement moves the driving gate in the corridor section in a longitudinal direction of the section, and moves the gate in the opposite direction after it has been brought outside the corridor section. A second transport arrangement pulls the gate sideways out from the corridor section in the plane of the gate through a gap in one side wall of the corridor section.
Patent AT-E400651-T1: [Translated] USE OF GREEN FLUORESCENT PROTEIN

PCT No. PCT/US94/10165 Sec. 371 Date Jun. 18, 1996 Sec. 102(e) Date Jun. 18, 1996 PCT Filed Sep. 9, 1994 PCT Pub. No. WO95/07463 PCT Pub. Date Mar. 16, 1995This invention provides a cell comprising a DNA molecule having a regulatory element from a gene, other than a gene encoding a green fluorescent protein operatively linked to a DNA sequence encoding the green fluorescent protein. This invention also provides living organisms which comprise the above-described cell. This invention also provides a method for selecting cells expressing a protein of interest which comprises: a) introducing into the cells a DNAI molecule having DNA sequence encoding the protein of interest and DNAII molecule having DNA sequence encoding a green fluorescent protein; b) culturing the introduced cells under conditions permitting expression of the green fluorescent protein and the protein of interest; and c) selecting the cultured cells which express green fluorescent protein, thereby selecting cells expressing the protein of interest. Finally, this invention provides various uses of a green fluorescent protein.
A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region:

Background:
          Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery, characterization, and genomic context of a novel human NBC-like gene, SLC4A9, on chromosome 5q31.
        
        
          Results:
          SLC4A9 was initially discovered by genomic sequence annotation and further characterized by sequencing of long-insert cDNA library clones. The predicted protein of 990 amino acids has 12 transmembrane domains and high sequence similarity to other NBCs. The 23-exon gene has 14 known mRNA isoforms. In three regions, mRNA sequence variation is generated by the inclusion or exclusion of portions of an exon. Noncoding SLC4A9 cDNAs were recovered multiple times from different libraries. The 3' untranslated region is fragmented into six alternatively spliced exons and contains expressed Alu, LINE and MER repeats. SLC4A9 has two alternative stop codons and six polyadenylation sites. Its expression is largely restricted to the kidney. In silico approaches were used to characterize two additional novel SLC4A genes and to place SLC4A9 within the context of multiple paralogous gene clusters containing members of the epidermal growth factor (EGF), ankyrin (ANK) and fibroblast growth factor (FGF) families. Seven human EGF-SLC4A-ANK-FGF clusters were found.
        
        
          Conclusion:
          The novel sodium bicarbonate cotransporter-like gene SLC4A9 demonstrates abundant alternative mRNA processing. It belongs to a growing class of functionally diverse genes characterized by inefficient highly variable splicing. The evolutionary history of the EGF-SLC4A-ANK-FGF gene clusters involves multiple rounds of duplication, apparently followed by large insertions and deletions at paralogous loci and genome-wide gene shuffling.
Patent AT-E400675-T1: [Translated] ANODE FOR GAS EVOLUTION REACTIONS

The invention describes an improved anode suitable for being installed in chlor-alkali electrolysis cells intercalated to cathode elements provided with a diaphragm. In operation, the anode of the invention is in direct contact with the diaphragm so as to form mutually equivalent vertical channels defined by the surfaces of the plates, of the supporting sheets and of the diaphragm, allowing a predefined and controlled upward motion of the chlorine-brine biphasic mixture.
Retrovirus-delivered siRNA

The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene function in mammalian cells. However, high production costs limit this technology's utility for many laboratories and experimental situations. Recently, several DNA-based plasmid vectors have been developed that direct transcription of small hairpin RNAs, which are processed into functional siRNAs by cellular enzymes. Although these vectors provide certain advantages over chemically synthesized siRNAs, numerous disadvantages remain including merely transient siRNA expression and low and variable transfection efficiency.
NNDSS - Table II. Tetanus to Varicella

NNDSS - Table II. Tetanus to Varicella - 2017.  In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed. The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories.

Note:
These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. 

Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. 

Footnotes:
 C.N.M.I.: Commonwealth of Northern Mariana Islands. 

 U: Unavailable. —: No reported cases. N: Not reportable. NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum. 

*Three low incidence conditions, rubella, rubella congenital, and tetanus, are in Table II to facilitate case count verification with reporting jurisdictions. 

† Case counts for reporting year 2017 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for tuberculosis are displayed in Table IV, which appears quarterly.
Penis size: Survey of female perceptions of sexual satisfaction

Background
          Does the size of the male penis, in terms of length or width, make a difference in female sexual satisfaction?
        
        
          Method
          To study the effect of penis width vs. length on female sexual satisfaction, 50 sexually active female undergraduate students were asked which felt better, i. e., was penis width or length more important for their sexual satisfaction.
        
        
          Results
          None reported they did not know, or that width and length were equally satisfying. A large majority, 45 of 50, reported width was more important (p < .001).
        
        
          Conclusion
          Implications are discussed, including the fact that the data seem to contradict Masters and Johnson about penis size having no physiological effect on female sexual satisfaction.
Compound 527043: N-cyclopentyl-N-methyl-benzamide

Chemical compound data from PubChem database. IUPAC Name: N-cyclopentyl-N-methylbenzamide. Molecular Formula: C13H17NO. Molecular Weight: 203.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2010 CMHS Uniform Reporting System (URS) Output Tables for South Carolina

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Beneficial effect of carboxy-PTIO on hemodynamic and blood gas changes in septic shock dogs

Background:
          Nitric oxide (NO) production following bacterial infection may play a physiological role in the host defense mechanism due to its antimicrobial activity. However, excess production of NO in severe infection such as sepsis has been implicated in the pathogenesis of septic shock. To determine whether a nitronyl nitroxide NO scavenger compound could prevent the hemodynamic and blood gas alterations in sepsis, bacterial lipopolysaccharide (LPS: 250ng/kg/min) was administered for 2 h in anesthetized dogs with or without infusion of carboxy-2-phenyl-4, 4, 5, 5-tetramethylimidazoline-1-oxyl-3-oxide (carboxy-PTIO: 0.1 mg/kg/min) for 1 h. Control animals received isotonic saline instead of LPS with or without carboxy-PTIO.
        
        
          Results:
          Infusion of LPS caused a marked decrease in mean arterial pressure (MAP), metabolic acidosis, and hypoxia. These effects were reversed by co-administration of carboxy-PTIO, without affecting other hemodynamic parameters. In control animals, neither hemodynamic nor blood gas parameters changed with or without carboxy-PTIO.
        
        
          Conclusion:
          These results indicate that carboxy-PTIO attenuates LPS-induced hypotension, metabolic acidosis, and hypoxia by scavenging excess NO from the circulation without affecting NO synthase (NOS) activity. An NO scavenger, carboxy-PTIO, may be preferable to non-selective NOS inhibitors for the treatment of human septic shock.
Evidence for an evolutionarily conserved interaction between cell wall biosynthesis and flowering in maize and sorghum

Background
          Factors that affect flowering vary among different plant species, and in the grasses in particular the exact mechanism behind this transition is not fully understood. The brown midrib (bm) mutants of maize (Zea mays L.), which have altered cell wall composition, have different flowering dynamics compared to their wild-type counterparts. This is indicative of a link between cell wall biogenesis and flowering. In order to test whether this relationship also exists in other grasses, the flowering dynamics in sorghum (Sorghum bicolor (L.) Moench) were investigated. Sorghum is evolutionarily closely related to maize, and a set of brown midrib (bmr) mutants similar to the maize bm mutants is available, making sorghum a suitable choice for study in this context.
        
        
          Results
          We compared the flowering time (time to half-bloom) of several different bmr sorghum lines and their wild-type counterparts. This revealed that the relationship between cell wall composition and flowering was conserved in sorghum. Specifically, the mutant bmr7 flowered significantly earlier than the corresponding wild-type control, whereas the mutants bmr2, bmr4, bmr6, bmr12, and bmr19 flowered later than their wild-type controls.
        
        
          Conclusion
          The change in flowering dynamics in several of the brown midrib sorghum lines provides evidence for an evolutionarily conserved mechanism that links cell wall biosynthesis to flowering dynamics. The availability of the sorghum bmr mutants expands the germplasm available to investigate this relationship in further detail.
New York (NY)

This report presents New York\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for New York for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 529208: Butanoic acid, 4-[bis(trimethylsilyl)amino]-, trimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 4-[bis(trimethylsilyl)amino]butanoate. Molecular Formula: C13H33NO2Si3. Molecular Weight: 319.66. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528960: Phenol, 2-(1-methylpropyl)-6-nitro

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-yl-6-nitrophenol. Molecular Formula: C10H13NO3. Molecular Weight: 195.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399766-T1: [Translated] AROMATIC HETEROCYCLES CONTAINING NITROGEN

The present invention concerns a process for preparing a compound represented by the following general formula (a-    nor a pharmacologically acceptable salt or hydrate thereof, which comprises reacting a compound repr    nwith a compound represented by the following general formula (a-4) :   nwherein the residues R 1 , R 2 , R sa1  - R sa3 , R 300 , R 301  and Z are as defined in the claims.
Compound 526325: 2,3,8-Tribromo-1,6-dichloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 2,3,8-tribromo-1,6-dichlorodibenzo-p-dioxin. Molecular Formula: C12H3Br3Cl2O2. Molecular Weight: 489.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400614-T1: [Translated] PRODUCTION AND USE OF ANTIMICROBIAL, POLYMERIZABLE MATERIALS IN MEDICAL TECHNOLOGY, PARTICULARLY IN THE HEARING AID ACOUSTICS AREA

A silicone paint comprises polyorganosiloxane containing at least two unsaturated groups in the molecule; a polyorganohydrogensiloxane containing at least two silicone hydride groups in the molecule; noble metal catalyst and non-toxic antimicrobial additive or a combination of at least two non-toxic antimicrobial additives. Independent claims are included for the following: (1) a two component addition-cross-linking silicone (wt.%): the polyorganosiloxanes containing at least two unsaturated groups in the molecule (0.1 - 70); the polyorganohydrogensiloxanes containing at least two SiH groups in the molecule (0.1 - 15); the noble metal catalyst (0.01 - 2) and the non-toxic antimicrobial additive or the combination of at least two non-toxic antimicrobial additives (0.1 - 5); and (2) a condensation-cross-linking silicone comprising a base component which comprises polyorganosiloxanes containing two end-position hydroxyl groups in the molecule; polyorganosiloxanes containing no reactive groups; and a non-toxic antimicrobial additive or a combination of at least two non-toxic antimicrobial additives and a curing component comprising catalyst for condensation cross-linking. ACTIVITY : Antimicrobial. MECHANISM OF ACTION : Microbial growth inhibitor. No biological data given.
Patent AT-E400578-T1: [Translated] PHOTOSENSIBILATORS THAT RECOGNIZE GALECTIN FOR PHOTODYNAMIC THERAPY

Purpurin-carbohydrate conjugates and their method of preparation and use for treatment of cancer cells. The conjugates have the general formula: <CHEM> where R6 and R7 taken together are -NR11 or are independently -OR11 where at least one R11 is preferably a mono or polysaccharide moiety and R1 - R8 are various groups formed from carbon and hydrogen and optionally oxygen and nitrogen where R3 and R4 may together form a covalent bond.
2011 CMHS Uniform Reporting System (URS) Output Tables for Alaska

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Report to Congress on the National Incidence Study of Child Abuse and Neglect, Supplementary Analysis

This report provides an overview of the purpose of the supplementary analysis as well as a summary of key findings. In the supplementary analysis, data from the NIS-4 and the National Child Abuse and Neglect Data System (NCANDS) were used to examine the comparability of information reported by the two studies on children investigated by Child Protective Services (CPS), including data on the number of children investigated, the dispositional outcome of investigation, the types of maltreatment experienced by children, and the children’s age, sex, and race/ethnicity.

Metadata-only record linking to the original dataset. Open original dataset below.
Motor Vehicle Occupant Death Rate, by Sex, 2012 & 2014, All States

Rate of deaths by age/gender (per 100,000 population) for motor vehicle occupants killed in crashes, 2012 & 2014. 2012 Source: Fatality Analysis Reporting System (FARS). 2014 Source: National Highway Traffic Safety Administration's (NHTSA) Fatality Analysis Reporting System (FARS), 2014 Annual Report File Note: Blank cells indicate data are suppressed. Fatality rates based on fewer than 20 deaths are suppressed.
Promoting Safe and Stable Families (PSSF) Program

The discretionary fund activities funded by the Promoting Safe and Stable Families (PSSF) Program are meant to develop a coordinated and integrated service system that builds on the strengths of families and communities; emphasize collaborative approaches, early identification of issues and the delivery of prevention, intervention and support services; prevent child abuse and neglect, protect children from further abuse, and promote permanency for children within their own families or with kinship or adoptive families; and strengthen families and remove barriers to child safety, permanency and well-being.

Metadata-only record linking to the original dataset. Open original dataset below.
Patent AT-E399741-T1: [Translated] PYROGENIC OXIDE POWDER, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN A SEPARATOR FOR AN ELECTROCHEMICAL CELL

A pyrogenic oxidic powder composed of particles, comprising (i) atoms of an element of groups 3A, 4A, 3B or 4B of the periodic table of the elements, and (ii) oxygen atoms, said particles being characterized by lithium atoms attached to said atoms via an oxygen bridge.
The NSDUH Report: Need for and Receipt of Substance Use Treatment among Asian Americans and Pacific Islanders

This report uses 2003 to 2011 National Survey on Drug Use and Health (NSDUH) to assess past year need for and receipt of alcohol use treatment and illicit drug use treatment among Asian Americans and Pacific Islanders aged 12 or older in comparison to persons of other racial and ethnic groups. Results are shown by age group, gender, federal poverty level and health insurance coverage status.
Sample Size and Population Estimates Tables (Standard Errors and P Values) - 8.1 to 8.13

These detailed tables show standard errors for sample sizes and population estimates from the 2010 National Survey on Drug Use and Health (NSDUH). Standard errors for samples sizes and population estimates are provided by age group, gender, race/ethnicity, education level, employment status, geographic area, pregnancy status, college enrollment status, and probation/parole status.