AndreaBozzo/ceres-open-data-index huggingface dataset:
Beverage specific alcohol intake in a population-based study: Evidence for a positive association between pulmonary function and wine intake

Background
          Lung function is a strong predictor of cardiovascular and all-cause mortality. Previous studies suggest that alcohol exposure may be linked to impaired pulmonary function through oxidant-antioxidant mechanisms. Alcohol may be an important source of oxidants; however, wine contains several antioxidants. In this study we analyzed the relation of beverage specific alcohol intake with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) in a random sample of 1555 residents of Western New York, USA.
        
        
          Methods
          We expressed pulmonary function as percent of predicted normal FEV1 (FEV1%) and FVC (FVC%) after adjustment for height, age, gender and race. To obtain information on alcohol intake we used a questionnaire that reliably queries total alcohol and beverage specific recent (past 30 days) and lifetime alcohol consumption. Results: Using multiple linear regression analysis after adjustment for covariates (pack-years of smoking, weight, smoking status, education, nutritional factors and for FEV1%, in addition, eosinophil count), we observed no significant correlation between total alcohol intake and lung function. However, we found positive associations of recent and lifetime wine intake with FEV1% and FVC%. When we analyzed white and red wine intake separately, the association of lung function with red wine was weaker than for white wine.
        
        
          Conclusion
          While total alcohol intake was not related to lung function, wine intake showed a positive association with lung function. Although we cannot exclude residual confounding by healthier lifestyle in wine drinkers, differential effects of alcoholic beverages on lung health may exist.
Patent AT-E400339-T1: [Translated] TOY RACING MACHINE FOR THE WALL

A motorized toy vehicle or Wall Racer that is capable of operating on vertical and inverted horizontal surfaces such as walls and ceilings, while being manufacturable at reasonable cost and operable on batteries (28) having sufficient lifetime as to be enjoyable. One or more battery-powered fans (10) draw air from around all or defined portions of the periphery of the interior volume of the Wall Racer through a carefully-shaped duct, so that the air in the portion of the duct immediately adjacent the surface flows at high velocity and low pressure; the relatively greater pressure of the surrounding air urges the vehicle against the surface, allowing it to adhere to vertical surfaces, such as walls, or operated inverted on horizontal surfaces, such as ceilings.
Compound 528311: Pyrazine, 2-pentyl-3-phenoxy

Chemical compound data from PubChem database. IUPAC Name: 2-pentyl-3-phenoxypyrazine. Molecular Formula: C15H18N2O. Molecular Weight: 242.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Psychosocial primary care – what patients expect from their General Practitioners A cross-sectional trial

Background
          Psychosocial Primary Care (PPC) is a model of service delivery for patients with mental disorders and psychosocial problems which was established in Germany in 1987. This study was performed as part of the evaluation of a PPC training program. We investigated patients' expectations of the psychosocial treatment offered by GPs trained in PPC.
        
        
          Methods
          Ten general practitioners trained in PPC were randomly selected. Two hundred and twenty patients were surveyed in the waiting room regarding their expectations concerning psychological treatment.
        
        
          Results
          Eighty-five per cent of patients could envisage making use of psychosocial treatments. Counselling by the GP was considered most important (65%). Fifty-four per cent of patients indicated that there was sufficient counselling, but further distinctions revealed dissatisfaction with both the extent and content of the counselling. Lack of time was the most frequent reason (53%) cited for insufficient counselling. A willingness to discuss the psychological aspects of illness was exhibited by between 55% (current illness) and 79% of patients. Two-thirds of patients believed that discussing psychological aspects and counselling by the doctor could exert a healing effect or contribute to symptomatic improvement in physical illnesses. Younger patients and patients with experience in psychotherapy expected referral to mental health services.
        
        
          Conclusions
          Primary care patients desire and accept psychological treatment from their GP. Training in psychosocial competence in primary care should be offered more frequently.
Patent AT-E400935-T1: [Translated] METHOD AND DEVICE FOR ADJUSTING EQUALIZER COEFFICIENTS AND FOR CONTROLLING THE SAMPLING RATE

Equalizer updating and accurate sampling rate control in a DMT receiver are simultaneously performed using a known signal, such as a pilot tone. The known signal is separated into its real and imaginary components. The equalizer uses separate mechanisms to process the real and imaginary components. The real component is used to control sampling rate timing in the receiver. The imaginary component of the received signal is used in an equalization adaptation procedure, e.g., updating an equalizer coefficient value. In one example embodiment, the real component of the received signal is set to zero for purposes of equalization, and the unequalized, real component is used to recover/track sampling rate timing. Because the real component has not been equalized, simultaneous timing recovery/tracking and equalization is achieved. Only the imaginary component is equalized and used to update the equalizer coefficient value. Thereafter, the unequalized real component and the equalized imaginary component are combined. In another example embodiment, a real-valued equalizer coefficient is determined for the known signal. Both real and imaginary components of the known sigal are equalized with the real-valued equalizer coefficient. The so-equalized real component adapts to a normalized amplitude for the timing control signal which is desirable in certain timing control applications. The equalized real and imaginary components are combined. The equalizer coefficient is updated using only the imaginary component of the received signal.
Benzodiazepines in Combination with Opioid Pain Relievers or Alcohol: Greater Risk of More Serious ED Visit Outcomes

This short report examines emergency department (ED) visits involving benzodiazepines, which are medications prescribed to relieve symptoms of anxiety, panic attacks and seizures.  It looks at the effect of combining benzodiazepines with opioid pain relievers or alcohol, both substances that also depress the central nervous system.  The report quantifies the increased risk of more serious outcomes such as hospitalization or, rarely, death in the ED, when benzodiazepines are combined with alcohol or opioid pain relievers.  The relationship between the patient’s age and the risk of more serious outcomes  between the risk of more serious outcomes and the age of the patient is also described.
Patent AT-E399641-T1: [Translated] FLAT PLATE PRECURSOR

A planographic printing plate precursor comprises: a support; and a recording layer disposed on the support, the recording layer comprising a lower layer and an upper layer disposed on the lower layer, wherein the lower layer contains a resin having in a main chain structure a phenol skeleton and a urea bond, the upper layer contains a water-insoluble alkali-soluble resin and an infrared absorber, and the solubility of the upper layer in an aqueous alkali solution is increased by exposure. The planographic printing plate precursor can be produced directly through scanning exposure based on digital signals. It is superior in reproducibility of highly fine images and also superior in printing durability and chemical resistance of small-area image areas such as halftone dots and thin lines.
Patent AT-E400185-T1: [Translated] EXTRACTION OF COMPOUNDS FROM DAIRY PRODUCTS

The present invention relates to processes for the treatment of dairy products and dairy process streams to produce lipids and substantially defatted protein streams. More specifically it relates to the use of near critical fluid extraction techniques to extract lipids from liquid dairy products and dairy process streams. Preferred solvents for use in the described near critical extraction techniques are ether based solvents that are partially miscible with water. A particularly preferred solvent for use in the invention is dimethyl ether.
Compound 526219: 1,2,3,4,6,8-Hexabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,3,4,6,8-hexabromodibenzofuran. Molecular Formula: C12H2Br6O. Molecular Weight: 641.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400817-T1: [Translated] MODULAR ANALYZING DEVICE

A new apparatus is disclosed that can be assembled quickly and reliably. The apparatus contains a transfer module (40), at least two support modules (20) firmly connected to said transfer module (40) and at least two carrier elements (A,B,C) firmly connected to said transfer module (40) and bearing said transfer module (40). The apparatus is particularly useful for performing multistep analytical processes that require precise access of tools of a transfer tool to items on a working area.
2015 CMHS Uniform Reporting System (URS) Table for Hawaii

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Hawaii. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Survey of transcripts in the adult

Background:
          Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then rescreening candidate lines for pleiotropic effects due to developmental defects. To accelerate the molecular analysis of brain function in Drosophila we constructed a cDNA library exclusively from adult brains. Our goal was to begin to develop a catalog of transcripts expressed in the brain. These transcripts are expected to contain a higher proportion of clones that are involved in neuronal function.
        
        
          Results:
          The library contains approximately 6.75 million independent clones. From our initial characterization of 271 randomly chosen clones, we expect that approximately 11% of the clones in this library will identify transcribed sequences not found in expressed sequence tag databases. Furthermore, 15% of these 271 clones are not among the 13,601 predicted Drosophila genes.
        
        
          Conclusions:
          Our analysis of this unique Drosophila brain library suggests that the number of genes may be underestimated in this organism. This work complements the Drosophila genome project by providing information that facilitates more complete annotation of the genomic sequence. This library should be a useful resource that will help in determining how basic brain functions operate at the molecular level.
Compound 529194: beta-Alanine, N-(tert-butyldimethylsilyl)-, tert-butyldimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 3-[[tert-butyl(dimethyl)silyl]amino]propanoate. Molecular Formula: C15H35NO2Si2. Molecular Weight: 317.61. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2013 NSDUH Tobacco Product and Alcohol Use Tables (Standard Errors and P Values) - 2.1 to 2.84

These detailed tables present standard errors for totals and prevalence estimates of tobacco and alcohol use from the 2013 National Survey on Drug Use and Health (NSDUH). Tobacco products include cigarettes, smokeless tobacco, cigars, and pipe tobacco. Alcohol use includes binge and heavy alcohol use. Standard errors are provided for lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area. Standard errors are provided for both 2013 and 2012.
Percentage of Hospitals Reporting Data to HHS by State

This dataset shows the overall percentage of hospitals reporting one or more elements for the previous week.  This is updated weekly on Mondays. 

The reported hospital list includes all hospitals registered with the Centers for Medicare & Medicaid Services (CMS), and non-CMS hospitals that have reported since July 15, 2020.  It does not include psychiatric, rehabilitation, Indian Health Service (IHS) facilities, U.S. Department of Veterans Affairs (VA) facilities, and religious non-medical facilities.
Patent AT-E401323-T1: [Translated] SYNTHESIS OF 2-BUTYL-3-(2'-(1-TRITYL-1H-TETRAZOLE- 5-YL)BIPHENYL-4-YL)-1,3-DIAZASPIRO-4,4 -NONEN-4-ONE

Provided is a novel method of making 2-butyl-3-[[2'(1-trityl-1H-tetrazol-5-yl)biphen-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are methods of making irbesartan.
Compound 525758: Heptyloxypropyloxydimethylsilane

Chemical compound data from PubChem database. IUPAC Name: heptoxy-dimethyl-propoxysilane. Molecular Formula: C12H28O2Si. Molecular Weight: 232.43. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Evolution and phylogeny of insect endogenous retroviruses

Background
          The genome of invertebrates is rich in retroelements which are structurally reminiscent of the retroviruses of vertebrates. Those containing three open reading frames (ORFs), including an env-like gene, may well be considered as endogenous retroviruses. Further support to this similarity has been provided by the ability of the env-like gene of DmeGypV (the Gypsy endogenous retrovirus of Drosophila melanogaster) to promote infection of Drosophila cells by a pseudotyped vertebrate retrovirus vector.
        
        
          Results
          To gain insights into their evolutionary story, a sample of thirteen insect endogenous retroviruses, which represents the largest sample analysed until now, was studied by computer-assisted comparison of the translated products of their gag, pol and env genes, as well as their LTR structural features. We found that the three phylogenetic trees based respectively on Gag, Pol and Env common motifs are congruent, which suggest a monophyletic origin for these elements.
        
        
          Conclusions
          We showed that most of the insect endogenous retroviruses belong to a major clade group which can be further divided into two main subgroups which also differ by the sequence of their primer binding sites (PBS). We propose to name IERV-K and IERV-S these two major subgroups of Insect Endogenous Retro Viruses (or Insect ERrantiVirus, according to the ICTV nomenclature) which respectively use Lys and Ser tRNAs to prime reverse transcription.
Compound 527561: 1,4-Cyclohexadiene, 1-bromo

Chemical compound data from PubChem database. IUPAC Name: 1-bromocyclohexa-1,4-diene. Molecular Formula: C6H7Br. Molecular Weight: 159.02. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?

Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis will be based on such cellular and genetic alterations. In particular, in 2051 sepsis will no longer be defined simply as a clinical constellation of findings, but rather will be divided into different entities dependent on the intracellular cascades or genes activated. Similarly, therapies will be specifically directed at such functional genetic or biochemical alterations, thereby permitting more rational therapy of specific cellular abnormalities in infected patients. Supportive care will also have advanced by 2051, allowing for less iatrogenic harm to critically ill septic patients. Finally, a better appreciation of the cellular and genetic pathways that are activated in patients will permit an improved understanding of prognosis in critically ill infected patients, allowing more appropriate use of therapies.
Vermont (VT)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Vermont for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 526281: 1,3,7,9-Tetrabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,3,7,9-tetrabromodibenzofuran. Molecular Formula: C12H4Br4O. Molecular Weight: 483.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526308: 2,3,4,6,8-Pentabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,3,4,6,8-pentabromodibenzofuran. Molecular Formula: C12H3Br5O. Molecular Weight: 562.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of

Background
          The signal transduction pathways mediated by retinoic acid play a critical role in the regulation of cell growth and differentiation during embryogenesis and hematopoiesis as well as in a variety of tumor cell lines in culture. Following the reports that two members of the superfamily of aldehyde dehydrogenase (ALDH) enzymes, ALDH1A1 and ALDH1A2, were capable of catalyzing the oxidation of all-trans retinal to all-trans retinoic acid with submicromolar Km values, we initiated an investigation of the ability of 4-(N,N-dipropylamino)benzaldehyde (DPAB) to inhibit the oxidation of retinal by purified mouse and human ALDH1A1.
        
        
          Results
          Our results show that DPAB potently inhibits retinal oxidation, with IC50 values of 0.11 and 0.13 μM for purified mouse and human ALDH1A1, respectively. Since the HL-60 human myeloid leukemic cell line has been used extensively to study the retinoic acid induced differentiation of HL-60 cells to granulocytes, and ALDH1A1 activity had previously been reported in HL-60 cells, we investigated the ability of DPAB to block differentiation of HL-60 promyelocytic leukemia cells exposed to retinal in culture. In HL-60 cells coincubated with 1 μM retinal and 50 μM DPAB for 144 hours, cell differentiation was inhibited only 30%. Furthermore, the NAD-dependent oxidation of propanal or retinal was less than 0.05 nmoles NADH formed/min-107 cells in spectrophotometric assays using HL-60 cell extracts.
        
        
          Conclusion
          Although ALDH1A1 may be the major catalytic activity for retinal oxidation in some retinoid-dependent mouse and Xenopus embryonic tissues and in adult human and mouse hematopoietic stem cells, another catalytic activity appears to synthesize the retinoic acid ligand necessary to stimulate the differentiation of HL-60 cells to end stage granulocytes.
Blog | COVID-19 Open Data – Our Data is Your Data

This blog post was posted by Kevin Duvall on December 18, 2020. It was written by Heather Strosnider, Co-Lead, Integrated Surveillance, Centers for Disease Control and Prevention (CDC)/Joint Coordination Cell; Kelly Bennett, Co-Lead, Integrated Surveillance, Assistant Secretary for Preparedness and Response (ASPR)/Joint Coordination Cell; Amy Gleason, Data Strategy and Execution Workgroup Lead, US Digital Service/Joint Coordination Cell; Kristen Honey, Chief Data Scientist and Senior Advisor to Assistant Secretary for Health (ASH), HHS; and Kevin Duvall, Deputy Chief Data Officer (CDO), Office of the CDO, U.S. Department of Health & Human Services (HHS).
Behavioral Health Barometer: New Jersey, 2013

This is a behavioral health report for the state of New Jersey. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment  for the years 2008 to 2012.
Compound 528778: Dihydropseudosmilagenin

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36,38,38,40,40,42,42,44,44,46,46,48,48,50,50,52,52,54,54,56,56,58,58,60,60,62,62,64,64,66,66,68,68,70,70,72,72,74,74-tetraheptacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59,61,63,65,67,69,71,73-heptatriacontaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70,72,74-heptatriacontasilacyclotetraheptacontane. Molecular Formula: C74H222O37Si37. Molecular Weight: 2743.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E40036-T1: [Translated] OSTEOSYNTHESIS PLATE FOR PRESSURE STABILIZATION.

An osteosynthesis plate for the pressure stabilization of bone fragments. To obtain great compression lengths without the need for a separate compression device. The plate is provided in each of its sections allocated to a bone fragment with two elongate slots which each contain several ramp hole sections, the pitch spacings of the ramp hole sections belonging to the same elongate slot being not greater than the number of the elongate slots allocated to the same bone fragment, multiplied by the useful ramp lengths. In general, two elongate slots suffice, in which the useful ramp length corresponds in each case to half a pitch spacing.
NCHS Survey Data Linked to Centers for Medicare & Medicaid Services (CMS) 1999-2013 Medicare Data

NCHS has linked data from various surveys with 1999-2013 Medicare program enrollment and health care utilization and expenditure data from the Centers for Medicare & Medicaid Services (CMS). Linkage of the NCHS survey participants with the CMS Medicare data provides the opportunity to study changes in health status, health care utilization and costs, and prescription drug use among Medicare enrollees. Medicare is the federal health insurance program for people who are 65 or older, certain younger people with disabilities, and people with End-Stage Renal Disease.