AndreaBozzo/ceres-open-data-index huggingface dataset:
Evidence for the adaptive significance of an LTR retrotransposon sequence in a

Background
          The potential adaptive significance of transposable elements (TEs) to the host genomes in which they reside is a topic that has been hotly debated by molecular evolutionists for more than two decades. Recent genomic analyses have demonstrated that TE fragments are associated with functional genes in plants and animals. These findings suggest that TEs may contribute significantly to gene evolution.
        
        
          Results
          We have analyzed two transposable elements associated with genes in the sequenced Drosophila melanogaster y; cn bw sp strain. A fragment of the Antonia long terminal repeat (LTR) retrotransposon is present in the intron of Chitinase 3 (Cht3), a gene located within the constitutive heterochromatin of chromosome 2L. Within the euchromatin of chromosome 2R a full-length Burdock LTR retrotransposon is located immediately 3' to cathD, a gene encoding cathepsin D. We tested for the presence of these two TE/gene associations in strains representing 12 geographically diverse populations of D. melanogaster. While the cathD insertion variant was detected only in the sequenced y; cn bw sp strain, the insertion variant present in the heterochromatic Cht3 gene was found to be fixed throughout twelve D. melanogaster populations and in a D. mauritiana strain suggesting that it maybe of adaptive significance. To further test this hypothesis, we sequenced a 685bp region spanning the LTR fragment in the intron of Cht3 in strains representative of the two sibling species D. melanogaster and D. mauritiana (~2.7 million years divergent). The level of sequence divergence between the two species within this region was significantly lower than expected from the neutral substitution rate and lower than the divergence observed between a randomly selected intron of the Drosophila Alcohol dehydrogenase gene (Adh).
        
        
          Conclusions
          Our results suggest that a 359 bp fragment of an Antonia retrotransposon (complete LTR is 659 bp) located within the intron of the Drosophila melanogaster Cht3 gene is of adaptive evolutionary significance. Our results are consistent with previous suggestions that the presence of TEs in constitutive heterochromatin may be of significance to the expression of heterochromatic genes.
CMS Program Statistics - Medicare Newly Enrolled

The CMS Program Statistics - Medicare Newly Enrolled tables provide data on characteristics of the newly enrolled Medicare population. 

For additional information on enrollment, providers, and Medicare use and payment, visit the CMS Program Statistics page.

 

Below is the list of tables:


	MDCR ENROLL AB 21.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Enrollees, Yearly Trend
	MDCR ENROLL AB 22.  Medicare Newly Enrolled Beneficiaries:  Total Enrollees by Month of Enrollment, Yearly Trend
	MDCR ENROLL AB 23.  Medicare Newly Enrolled Beneficiaries:  Total Enrollees, by Demographic Characteristics
	MDCR ENROLL AB 24.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Enrollees, by Area of Residence
	MDCR ENROLL AB 25.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Original Medicare Enrollees
	MDCR ENROLL AB 26.  Medicare Newly Enrolled Beneficiaries:  Original Medicare Enrollees by Month of Enrollment, Yearly Trend
	MDCR ENROLL AB 27.  Medicare Newly Enrolled Beneficiaries:  Original Medicare Enrollees, by Demographic Characteristics
	MDCR ENROLL AB 28.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Original Medicare Enrollees, by Area of Residence
	MDCR ENROLL AB 29.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Medicare Advantage and Other Health Plan Enrollees, Yearly Trend
	MDCR ENROLL AB 30.  Medicare Newly Enrolled Beneficiaries:  Medicare Advantage and Other Health Plan Enrollees, by Month of Enrollment, Yearly Trend
	MDCR ENROLL AB 31.  Medicare Newly Enrolled Beneficiaries:  Medicare Advantage and Other Health Plan Enrollees, by Demographic Characteristics
	MDCR ENROLL AB 32.  Medicare Newly Enrolled Beneficiaries:  Total, Aged, and Disabled Medicare Advantage and Other Health Plan Enrollees, by Area of Residence
Avian papillomaviruses: the parrot

Background
          An avian papillomavirus genome has been cloned from a cutaneous exophytic papilloma from an African grey parrot (Psittacus erithacus). The nucleotide sequence, genome organization, and phylogenetic position of the Psittacus erithacus papillomavirus (PePV) were determined. This PePV sequence represents the first complete avian papillomavirus genome defined.
        
        
          Results
          The PePV genome (7304 basepairs) differs from other papillomaviruses, in that it has a unique organization of the early protein region lacking classical E6 and E7 open reading frames. Phylogenetic comparison of the PePV sequence with partial E1 and L1 sequences of the chaffinch (Fringilla coelebs) papillomavirus (FPV) reveals that these two avian papillomaviruses form a monophyletic cluster with a common branch that originates near the unresolved center of the papillomavirus evolutionary tree.
        
        
          Conclusions
          The PePV genome has a unique layout of the early protein region which represents a novel prototypic genomic organization for avian papillomaviruses. The close relationship between PePV and FPV, and between their Psittaciformes and Passeriformes hosts, supports the hypothesis that papillomaviruses have co-evolved and speciated together with their host species throughout evolution.
Runaway and Homeless Youth Management Information System (1997)

It is estimated that over a million young people run away or become homeless each year.  These youth face increasingly complex issues, including substance abuse, physical and sexual abuse, and AIDS.  The serious issues faced by these youths are coupled with funding constraints among almost all agencies providing services to this population.In 1974 the Family and Youth Services Bureau (FYSB) authorized funding to assist community based programs to serve youth who were not otherwise being served by traditional human service agencies.  The funding was used for the operation of basic center programs which would provide support for runaway and homeless youth (RHY).  The programs offered emergency shelter, crisis intervention services, and family reunification services. In 1988 the Transitional Living Program was introduced in order to provide services to older youth requiring assistance in becoming self-sufficient. While helping to support at-risk youth, the FYSB laws also mandate that certain data be regularly collected and reported. For example, FYSB supported agencies must report on the profile of the youth and families they serve, and provide an overview of the services which they deliver under their grant programs.  In order to assist these grantees in their reporting responsibilities, FYSB funded the development of a Runaway and Homeless Youth Management Information System (RHY MIS).   The RHY MIS was designed to provide comprehensive information on youth served, services provided, and programs which provide the services.The RHY MIS was designed, developed, and implemented by Information Technology International (ITI).  Gradual implementation of the MIS began in 1992 with approximately 400 RHY grantee sites across the country.  By 1995, virtually all existing grant programs had at least one staff member who had been trained and grantees were expected to use the MIS and submit data to FYSB on a quarterly basis. The fiscal year 1997 RHY MIS dataset contains data submitted during the federal fiscal year 1997.  Data are included from participating agencies in 53 U.S. States and Territories.  The dataset includes three files.  A demographics file contains 84846 observations and 153 variables.  Two additional files contain 68100 observations and a combined 235 variables pertaining to youth problems and services provided.

Investigators: Buechler, Joe
Compound 526795: Tetrahydro-6-pentadecyl-2H-pyran-2-one

Chemical compound data from PubChem database. IUPAC Name: 6-pentadecyloxan-2-one. Molecular Formula: C20H38O2. Molecular Weight: 310.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525546: 3-Methyl-1,8-bis[(trimethylsilyl)oxy]anthra-9,10-quinone

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-1,8-bis(trimethylsilyloxy)anthracene-9,10-dione. Molecular Formula: C21H26O4Si2. Molecular Weight: 398.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401048-T1: [Translated] PACKAGING FOR PLASTERS

The package comprises a metal, plastic or paper transparent and or translucent support(1) on which individual plasters (2) are placed. The support is folded once to form a folder enclosing the plasters and reversibly covering a fastening in the form of a hook-pile or press-stud or adhesive fastening. The fastening may consist of an adhesive applied (12) to the inside of the folder. The surface of the adhesive applied is smaller than the surface of the fastening strip (11). The edges of the folder have a sealing strip (14).
Weekly United States COVID-19 Cases and Deaths among Dialysis Patients - ARCHIVED

Mandated reporting of Weekly Aggregate Case and Death Count data among dialysis patients and dialysis facility staff (healthcare personnel or HCP) in the United States was discontinued May 11, 2023, with the expiration of the COVID-19 public health emergency declaration. This dataset will contain weekly aggregate data from January 1, 2021, through May 10, 2023, and will remain publicly available.

This archived public use dataset contains reported COVID-19 case and death data per week for all states and territories, along with weekly totals for the entire United States, throughout the given timeframe.
Compound 526037: Trimethyl-[[13-methyl-3,15,16-tris(trimethylsilyloxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]silane

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[[13-methyl-3,15,16-tris(trimethylsilyloxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]silane. Molecular Formula: C30H56O4Si4. Molecular Weight: 593.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hospital Cost Report Audited Data: 2011

This version of the Institutional Cost Report (ICR) has been audited by a Certified Public Accounting Firm. The ICR is a uniform report completed by New York State hospitals to report income, expenses, assets, liabilities, and statistics to the the Department of Health (DOH). Under DOH regulations, (Part 86-1.2), Article 28 hospitals are required to file financial and statistical data with DOH annually. The data filed is part of the ICR and is received electronically through a secured network. This data is used to develop Medicaid rates, assist in the formulation of reimbursement methodologies, and analyze trends. For more information, check out: http://www.health.ny.gov/facilities/hospital/index.htm.
Florida AFCARS Assessment Review

This webpage includes the documentation from Florida's Adoption and Foster Care Analysis and Reporting System (AFCARS) assessment review for fiscal year 2012:

AFCAR Assessment Review Findings - Letter (PDF) (PDF - 78 KB)

AFCARS Assessment Review Report - Florida (PDF) (PDF - 152 KB)

Tab A - Detailed Findings (PDF) (PDF - 7 KB)

Findings Instructions (PDF) (PDF - 52 KB)

Section I - General Requirements (PDF) (PDF - 8 KB)

AFCARS Assessment Review Findings - General Requirement (PDF) (PDF - 304 KB)

Section II - Foster Care and Adoption Elements (PDF) (PDF - 8 KB)

AFCARS Assessment Review Findings - Foster Care and Adoption Data Elements (PDF) (PDF - 601 KB)

Section III - Case File Review (PDF) (PDF - 7 KB)

AFCARS Case File Summary Report - Florida (PDF) (PDF - 80 KB)

AFCARS Assessment Review Case File Findings - Foster Care and Adoption Data Elements (PDF) (PDF - 204 KB)

Tab B - AFCARS Improvement Plan (PDF) (PDF - 7 KB)

Improvement Plan Instructions (PDF) (PDF - 84 KB)

Section I - General Requirements (PDF) (PDF - 8 KB)

AFCARS Assessment Review Improvement Plan - General Requirements (PDF) (PDF - 304 KB)

Section II - Foster Care and Adoption Elements (PDF) (PDF - 8 KB)

AFCARS Assessment Review Improvement Plan - Foster Care and Adoption Data Elements (PDF) (PDF - 482 KB)

Metadata-only record linking to the original dataset. Open original dataset below.
Elevated muscle mass accompanied by transcriptional and nuclear alterations several months following cessation of resistance-type training in rats

Loading-induced hypertrophy with transcriptional upregulation has been observed concomitant with nuclei accretion in various studies regarding both humans and rodents.   Bruusgaard et al. in 2010 pioneered work utilizing a model of synergist ablation to cause hypertrophy followed by denervation-induced atrophy to demonstrate that load-induced gains in myonuclei could be long-lasting after the termination of such exposure.  This finding was consistent with the idea of enduring myonuclear accretion as a form of “muscle memory” allowing enhanced muscle adaptation following a period of detraining.  Subsequent research groups further investigated this possibility in the context of exercise utilizing rodents and various loaded exercise paradigms such as weighted wheel running and ladder climbing.  This research yielded a spectrum of results.  While these studies were instrumental in highlighting the variation in outcomes possible following load-induced hypertrophy in general, they were limited in their direct relatedness to resistance training – the predominate form of exposure utilized to induce hypertrophy.  Our research group has established and repeatedly validated a rat research model to investigate resistance-type training.   The model is based on using a dynamometer to precisely expose dorsiflexor muscles of rats to 8 sets of 10 repetitions (per set) of stretch-shortening contractions (SSCs) – a consecutive sequence of isometric, lengthening, and shortening contractions.  Training with this exposure 3 sessions per week for one month results in increases in muscle mass and performance.  This is accompanied by an increase in muscle fiber area accompanied by a proportional increase in myonuclei number and a rise in overall transcriptional output as measured by total RNA levels.  The purpose of the present study was to determine to what extent alterations in performance, muscle mass, nuclei number, and transcriptional output persist several months following the termination of this relevant and valid model of resistance-type training.
Patent AT-E401118-T1: [Translated] METHOD FOR REDUCING THE HEAVY METAL CONTENT OF FUME GASES

A method for reducing heavy metals, in particular in mercury, present in flue gases, includes the step of bringing the flue gases into contact with a particular class of sorbent material in the dry state. A preferred class of dry sorbent materials can be provided from a mineral compound selected from among halloysites and phyllosilicates of the palygorskite subgroup and the sepiolite subgroup of the palygorskite-sepiolite group according to the Dana classification. Mineral compounds of this group have been shown to provide a reduction in heavy metals, in particular in mercury, present in flue gases.
AH Provisional COVID-19 Deaths by Hospital Referral Region

Provisional count of deaths involving coronavirus disease 2019 (COVID-19) in the United States by week of death and by hospital referral region (HRR). HRR is determined by county of occurrence. Weekly weighted counts of deaths from all causes and due to COVID-19 are provided by HRR overall and for decedents 65 years and older. The weighted counts by HRRs are based on published methods for aggregating county-level data to HRRs. More detail about aggregating to HRRs from counties can be found in the following: https://github.com/Dartmouth-DAC/covid-19-hrr-mapping
https://dartmouthatlas.org/covid-19/hrr-mapping/
Compound 527322: methyl 2-[5-(4-chlorophenyl)-2-phenyl-2H-imidazol-4-yl]acetate

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[5-(4-chlorophenyl)-2-phenyl-2H-imidazol-4-yl]acetate. Molecular Formula: C18H15ClN2O2. Molecular Weight: 326.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400854-T1: [Translated] USER INTERFACE AND METHOD FOR VEHICLE CONTROL SYSTEM

A vehicle system comprises a control system for an equipment service vehicle and a personal digital assistant. The control system comprises a power source, a power transmission link, a plurality of input devices, a plurality of output devices, a plurality of microprocessor-based interface modules and a communication network. The plurality of interface modules are coupled to the power source by way of the power transmission link. The plurality of interface modules are interconnected to each other by way of the communication network. Each of the plurality of interface modules are coupled to respective ones of the plurality of input devices and the plurality of output devices. The plurality of interface modules store I/O status information for the plurality of input devices and the plurality of output devices. The control system is configured to wirelessly communicate at least some of the I/O status information to the personal digital assistant.
Cell contact interactions in rheumatology, The Kennedy Institute for Rheumatology, London, UK, 1-2 June 2000

The intricate interactions that regulate relationships between endogenous tissue cells and infiltrating immune cells in the rheumatic joint, particularly in rheumatoid arthritis (RA), were the subject of the meeting. A better understanding of these interactions might help to define intervention points that could be used to develop specific therapies. The presentations and discussions highlighted the fact that, once chronic inflammation is established, several pro-inflammatory loops involving tumour necrosis factor (TNF)-α and interleukin (IL)-1β can be defined. Direct cellular contact with stimulated T lymphocytes induces TNF-α and IL-1β in monocytes which in turn induce functions in fibroblast-like synoviocytes. The latter include the production of stromal cell-derived factor-1α (SDF-1α) which enhances the expression of CD40L in T cells, which stimulates SDF-1α production in synoviocytes, which in turn protects T and B cells from apoptosis and enhances cell recruitment thus favoring inflammatory processes. IL-1β and TNF-α also induce IL-15 in fibroblast-like synoviocytes, which induces the production of IL-17 which in turn potentiates IL-1β and TNF-α production in monocyte-macrophages. This underlines the importance of TNF-α and IL-1β in RA pathogenesis, and helps explain the efficiency of agents blocking the activity of these cytokines in RA. Factors able to block the induction of cytokine production (such as apolipoprotein A-I [apo A-I] and interferon [IFN]-β) might interfere more distally in the inflammatory process. Furthermore, stimulated T lymphocytes produce osteoclast differentiation factor (ODF), which triggers erosive functions of osteoclasts. Therefore, factors capable of affecting the level of T lymphocyte activation, such as IFN-β, IL-15 antagonist, or SDF-1α antagonist, might be of interest in RA therapy.
Compound 528153: N'-methylpyridine-2-carboximidamide

Chemical compound data from PubChem database. IUPAC Name: N'-methylpyridine-2-carboximidamide. Molecular Formula: C7H9N3. Molecular Weight: 135.17. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
IT Business Collaboration

LeadingAgile (Children’s Bureau contracted Agile implementation consultants) led a webinar on how to promote strong, collaborative relationships between program staff and information technology (IT) staff. While much of the content was in the context of Agile collaboration, this presentation was designed to be of benefit to those practicing all types of IT development approaches.

The discussion about lessons learned on strong collaboration between program staff and IT staff stems from LeadingAgile’s firsthand experience with IT system development teams. The webinar began with a brief overview of Agile and various ways Agile lends itself to increased collaboration. The rest of the presentation discussed roles within development activities, collaboration and feedback loops, and common challenges that organizations face in both Agile as well as traditional project management settings.

During the later portion of the webinar, LeadingAgile facilitated a panel-style Q&A session.

Metadata-only record linking to the original dataset. Open original dataset below.
COVID-19 Vaccine Delivery - Historical

Note: This dataset is historical only. -- COVID-19 vaccine delivered to providers in the City of Chicago. Daily counts are shown for the total number of doses delivered as well as cumulative totals as of that date.

Data are updated Monday to Friday. As of the launch of this dataset, weekend deliveries are unusual but will be added to the appropriate date (i.e., Saturday or Sunday) the following Monday if they occur.

All data are provisional and subject to change. Information is updated as additional details are received. At any given time, this dataset reflects data currently known to CDPH.

Numbers in this dataset may differ from other public sources due to when data are reported and how City of Chicago boundaries are defined.

For information about the number of vaccine doses administered by Chicago providers, see https://data.cityofchicago.org/Health-Human-Services/COVID-19-Daily-Vaccinations-Administered-in-Chicag/4564-ixr2. For information about the number of vaccine doses administered to Chicago residents and number of residents considered fully vaccinated regardless of if they were vaccinated in Chicago, see https://data.cityofchicago.org/Health-Human-Services/COVID-19-Daily-Vaccinations-Chicago-Residents/2vhs-cf6b.

For all datasets related to COVID-19, see https://data.cityofchicago.org/browse?limitTo=datasets&sortBy=alpha&tags=covid-19.

Data Sources: Vaccine Tracking System (VTrcks)
Compound 525136: Butyl octyl isophthalate

Chemical compound data from PubChem database. IUPAC Name: 1-O-butyl 3-O-octyl benzene-1,3-dicarboxylate. Molecular Formula: C20H30O4. Molecular Weight: 334.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528268: Butanedioic acid, phenylmethyl propyl ester

Chemical compound data from PubChem database. IUPAC Name: 4-O-benzyl 1-O-propyl butanedioate. Molecular Formula: C14H18O4. Molecular Weight: 250.29. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529523: Bialaphos, TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[2-[[2-[[tert-butyl(dimethyl)silyl]amino]-4-[[tert-butyl(dimethyl)silyl]oxy-methylphosphoryl]butanoyl]amino]propanoylamino]propanoate. Molecular Formula: C29H64N3O6PSi3. Molecular Weight: 666.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.