AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E399798-T1: [Translated] CELLULOSE DERIVATIVES HAVING GEL-LIKE RHEOLOGICAL PROPERTIES AND METHOD FOR PRODUCING THE SAME

Cellulose ethers with gel-like rheological properties in aqueous solution are produced by irreversibly crosslinking the cellulose ether obtained by reacting alkalized cellulose with alkylene oxide and alkyl halide.  Cellulose ethers with gel-like rheological properties in aqueous solution (I), obtained by: (a) alkalizing cellulose with aqueous alkali hydroxide solution (II) in presence of a suspending agent (III); (b) reacting with alkylene oxide(s), reacting with an alkyl halide contained in (III); (c) reacting (subsequently or simultaneously) with 0.0001-0.05 equivalents (eq.) crosslinking agent (i.e. moles per mol anhydroglucose units (AGU)); and (d) separating the irreversibly crosslinked derivative from the reaction mixture (optionally after further addition of (II) and/or alkylating agent), optionally purifying and then drying the product.. An Independent claim is also included for a method as described above for the production of (I).
Promotion, Prevention, and Treatment: Reducing the Risk and Impact of Maltreatment on Very Young Children

Early experiences profoundly shape and have lifelong affects in developing the person we become. The mission of ZERO TO THREE is to promote the health and development of infants and toddlers. The presenters described how that mission keeps them in touch with the cutting edge of clinical knowledge and experience in order for them to develop a range of practical approaches that child welfare practitioners can use in working with very young children and their families.

Presenters: Nancy Seibel, Director, Center for Training Services, ZERO TO THREE; and Lucy Hudson, Director, Court Teams for Maltreated Infants and Toddlers Project, ZERO TO THREE

View Webinar (WMV - 60 MB)

Metadata-only record linking to the original dataset. Open original dataset below.
QHP Landscape PY2022 Individual Dental

The Dental Individual Market file of the QHP Landscape Files contains information on certified dental plans offered through an Exchange to consumers in the individual market. These plans are also known as Stand-alone Dental Plans (SADPs). The file reports plans offered by county for states in the Federally-facilitated Exchanges including states performing plan management functions, and State Based Exchanges using the federal platform for eligibility and enrollment.
Weekly Differences in Cumulative Percentage of Children Ages 6 Months -17 Years who are up to date with the updated 2023-24 COVID-19 Vaccine, by Selected Demographics

• Weekly COVID-19 vaccination coverage estimates among children 6 months to 17 years is assessed through the National Immunization Survey (https://www.cdc.gov/vaccines/imz-managers/nis/about.html). 

• Weekly estimates of COVID-19 vaccination coverage among children through December 31, 2023, were calculated using data from the National Immunization Survey-Child COVID Module (NIS-CCM) (https://www.cdc.gov/vaccines/imz-managers/nis/about.html#nis-ccm). Beginning January 2, 2024, the NIS-CCM was discontinued, and questions regarding receipt of COVID-19 vaccination among children were added to the NIS-Flu (https://www.cdc.gov/vaccines/imz-managers/nis/about.html#nis-cim). 

• Starting in September 2023, the CDC recommended the 2023-2024 updated COVID-19 vaccine to protect against serious illness from COVID-19.
CMS Program Statistics - Medicare Premiums

The CMS Program Statistics - Medicare Premium tables provide information on counts of Medicare Part A (Hospital Insurance) and Part B (Medical Insurance) total premium, standard base premium, reduced base premium, and penalty beneficiaries. In addition, these tables include premium amounts and penalty amounts. For the Part B premium tables, information on Income Related Monthly Adjustment Amount (IRMAA) beneficiaries, IRMAA amounts, Managed Care Reduction beneficiaries and Managed Care Reduction amounts are also included. 

For additional information on enrollment, providers, and Medicare use and payment, visit the CMS Program Statistics page.

 

Below is the list of tables:


	MDCR PREMIUMS 1. Medicare Premiums:  Medicare Part A Premium Beneficiaries and Amounts, Yearly Trend
	MDCR PREMIUMS 2. Medicare Premiums:  Medicare Part A Premium Beneficiaries and Amounts by Demographic Characteristics and Medicare-Medicaid Enrollment Status
	MDCR PREMIUMS 3. Medicare Premiums:  Medicare Part A Premium Beneficiaries and Amounts, by Area of Residence
	MDCR PREMIUMS 4. Medicare Premiums:  Medicare Part B Premium Beneficiaries and Amounts, Yearly Trend
	MDCR PREMIUMS 5. Medicare Premiums:  Medicare Part B Premium Beneficiaries and Amounts by Demographic Characteristics and Medicare-Medicaid Enrollment Status
	MDCR PREMIUMS 6. Medicare Premiums:  Medicare Part B Premium Beneficiaries and Amounts, by Area of Residence
	MDCR PREMIUMS 7. Medicare Premiums: Medicare Part D Premium Beneficiaries and Amounts, Yearly Trend
	MDCR PREMIUMS 8. Medicare Premiums: Medicare Part D Premium Beneficiaries and Amounts, by Demographic Characteristics and Medicare-Medicaid Enrollment Status
	MDCR PREMIUMS 9. Medicare Premiums: Medicare Part D Premium Beneficiaries and Amounts, by Area of Residence
In vivo involvement of polymorphonuclear neutrophils in Leishmania infantum infection

Background
          The role of lymphocytes in the specific defence against L. infantum has been well established, but the part played by polynuclear neutrophil (PN) cells in controlling visceral leishmaniasis was much less studied. In this report we examine in vivo the participation of PN in early and late phases of infection by L. infantum.
        
        
          Results
          Promastigote phagocytosis and killing occurs very early after infection, as demonstrated by electron microscopy analyses which show in BALB/c mouse spleen, but not in liver, numerous PN harbouring ultrastructurally degraded parasites. It is shown, using mAb RB6-8C5 directed against mature mouse granulocytes, that in chronically infected mice, long-term PN depletion did not enhance parasite counts neither in liver nor in spleen, indicating that these cells are not involved in the late phase of L. infantum infection. In acute stage of infection, in mouse liver, where L. infantum load is initially larger than that in spleen but resolves spontaneously, there was no significant effect of neutrophils depletion. By contrast, early in infection the neutrophil cells crucially contributed to parasite killing in spleen, since PN depletion, performed before and up to 7 days after the parasite inoculation, resulted in a ten-fold increase of parasite burden.
        
        
          Conclusions
          Taken together these data show that neutrophil cells contribute to the early control of the parasite growth in spleen but not in liver and that these cells have no significant effect late in infection in either of these target organs.
Compound 529058: 1,3,5-Dithiazine, perhydro-6-butyl-2,4-dimethyl

Chemical compound data from PubChem database. IUPAC Name: 4-butyl-2,6-dimethyl-1,3,5-dithiazinane. Molecular Formula: C9H19NS2. Molecular Weight: 205.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Kansas (KS)

This report presents Kansas\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Kansas for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Adult Day Health Centers

[<a href='https://files.hawaii.gov/dbedt/op/gis/data/Adult_Day_Health_Centers.pdf' target='_blank' rel='nofollow ugc noopener noreferrer'>Metadata</a>] Locations of adult day health centers in the State of Hawaii as of November 2021. Source: Created by Hawaii Statewide GIS Program from data downloaded from Hawaii State Department of Health Office of Health Care Assurance (OHCA), November 2021. For more information, please see metadata at <a href='https://files.hawaii.gov/dbedt/op/gis/data/Adult_Day_Health_Centers.pdf' target='_blank' rel='nofollow ugc noopener noreferrer'>https://files.hawaii.gov/dbedt/op/gis/data/Adult_Day_Health_Centers.pdf</a> or contact Hawaii Statewide GIS Program, Office of Planning and Sustainable Development, State of Hawaii; PO Box 2359, Honolulu, Hi. 96804; (808) 587-2846; email: gis@hawaii.gov; Website: <a href='https://planning.hawaii.gov/gis' target='_blank' rel='nofollow ugc noopener noreferrer'>https://planning.hawaii.gov/gis</a>.
Nateglinide

Nateglinide is a prescription medication used to help manage type 2 diabetes by lowering blood sugar levels. It works as a glinide that stimulates insulin release from the pancreas. Available as oral tablets in 60 mg and 120 mg strengths, it's manufactured by Rising Pharma Holdings, Inc. under application ANDA205544. This information was generated using AI and is provided for informational and research purposes only.
National Survey of Substance Abuse Treatment Services: State Profiles 2003

The 2003 National Survey of Substance Abuse Treatment Services (N-SSATS) is an annual survey of facilities providing substance abuse treatment. The N-SSATS, conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), is designed to collect data on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse facilities (both public and private) throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.
Comparison of Physical Health Conditions among Adolescents Aged 12 to 17 with and without Major Depressive Episode

The purpose of this report is to examine the prevalence of MDE among adolescents with varying levels of self-rated overall health and with and without three respiratory health conditions (asthma, bronchitis, pneumonia), body mass index category (including overweight and obesity), and diabetes using data from a nationally representative household sample, the National Survey on Drug Use and Health (NSDUH). These health conditions were examined because, based on prior research, they have been shown to be associated with depression. This study also takes the next step of furthering knowledge about whether the associations between depression and physical health conditions differ among particular populations by exploring whether these associations differ by age, gender, race/ethnicity, and poverty status.
S-carboxymethylcysteine in the treatment of glue ear: quantitative systematic review

Objective
          To establish the clinical relevance of S-carboxymethylcysteine in the treatment of glue ear in children using measures approximating those saving a child from operation for grommet insertion.
        
        
          Data sources
          Cochrane Library, MEDLINE, EMBASE, PubMed, reference lists and reviews were used for randomised controlled trials comparing S-carboxymethylcysteine with placebo. Seven trials involving 283 children and 146 ears were found.
        
        
          Review methods
          Studies were randomised, double-blind comparisons of S-carboxymethylcysteine (any dose and duration) with placebo in otitis media with effusion. Quality of trial reporting and validity of methods were assessed and used in sensitivity analysis. Main outcomes were relative benefit and number-needed-to-treat to prevent one grommet operation compared with placebo.
        
        
          Results
          Successful outcomes were obtained in 17% of children given placebo (range 5% to 38% in individual studies) and in 35% of children given S-carboxymethylcysteine (range 22 to 80%). For combined data (children and ears) the relative benefit was 2.0 (95%CI 1.4 to 2.8) and number-needed-to-treat 5.5 (95% confidence interval 3.8 to 9.8). Pooled data from trials of higher reporting quality (4/7) or methodological validity (3/7) tended to have lower efficacy but were not statistically different from those of lower quality or validity.
        
        
          Conclusion
          S-carboxymethylcysteine is effective in the treatment of children with glue ear. For every five or six children treated with S-carboxymethylcysteine over one to three months, one will not undergo surgery for grommet insertion who would have done had they been given placebo. The confidence in this conclusion is limited because studies included relatively few children.
Measurement of microbial activity in soil by colorimetric observation of

Background
          Detecting microbial life in extraterrestrial locations is a goal of space exploration because of ecological and health concerns about possible contamination of other planets with earthly organisms, and vice versa. Previously we suggested a method for life detection based on the fact that living entities require a continual input of energy accessed through coupled oxidations and reductions (an electron transport chain). We demonstrated using earthly soils that the identification of extracted components of electron transport chains is useful for remote detection of a chemical signature of life. The instrument package developed used supercritical carbon dioxide for soil extraction, followed by chromatography or electrophoresis to separate extracted compounds, with final detection by voltammetry and tandem mass-spectrometry.
        
        
          Results
          Here we used Earth-derived soils to develop a related life detection system based on direct observation of a biological redox signature. We measured the ability of soil microbial communities to reduce artificial electron acceptors. Living organisms in pure culture and those naturally found in soil were shown to reduce 2,3-dichlorophenol indophenol (DCIP) and the tetrazolium dye 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt (XTT). Uninoculated or sterilized controls did not reduce the dyes. A soil from Antarctica that was determined by chemical signature and DNA analysis to be sterile also did not reduce the dyes.
        
        
          Conclusion
          Observation of dye reduction, supplemented with extraction and identification of only a few specific signature redox-active biochemicals such as porphyrins or quinones, provides a simplified means to detect a signature of life in the soils of other planets or their moons.
NNDSS - Table II. West Nile to Zika

NNDSS - Table II. West Nile to Zika  - 2018. In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed. The Table includes total number of cases reported in the United States, by region and by states or territory.

Note:

This table contains provisional cases of selected national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up.  Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:

C.N.M.I.: Commonwealth of Northern Mariana Islands. 
U: Unavailable. —: No reported cases. N: Not reportable. NA:  Not Available.  NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum. 

* Case counts for reporting years 2017 and 2018 are provisional and subject to change. Data for years 2013 through 2016 are finalized. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf.  

† Not reportable in all jurisdictions. Reporting exceptions are available at http://wwwn.cdc.gov/nndss/downloads.html.
Patent AT-E400184-T1: [Translated] PASTEURIZATION OF EGGS IN THE SHELL

An in-shell egg pasteurization installation includes a temperature raising stage having a microwave cavity or microwave cavity portion into which microwaves can be radiated and a pasteurization stage having a microwave cavity or microwave cavity portion into which microwaves can be radiated. The installation is configured so as to provide radiant or conductive heat to an in-shell egg located in the temperature raising stage and to an in-shell egg located in the pasteurization stage, and to provide relative displacement between an in-shell egg and the microwave cavities or microwave cavity portions.
4.22a Facility licensing, certification, or accreditation of facilities with Opioid Treatment Programs (OTPs), by type of care offered: 2011. Number

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing facility licensing, certification, or accreditation of facilities with Opioid Treatment Programs (OTPs), by type of care offered in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.
Compound 525172: Nonapropylene glycol, diacetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-[2-[2-[2-[2-(2-acetyloxypropoxy)propoxy]propoxy]propoxy]propoxy]propoxy]propoxy]propoxy]propyl acetate. Molecular Formula: C31H60O12. Molecular Weight: 624.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Imaging of Dynamic Changes of the Actin Cytoskeleton in Microextensions of Live NIH3T3 Cells with a GFP Fusion of the F-Actin Binding Domain of Moesin

Background
          The cell surface undergoes continuous change during cell movement. This is characterized by transient protrusion and partial or complete retraction of microspikes, filopodia, and lamellipodia. This requires a dynamic actin cytoskeleton, moesin, components of Rho-mediated signal pathways, rearrangement of membrane constituents and the formation of focal adhesion sites. While the immunofluorescence distribution of endogenous moesin is that of a membrane-bound molecule with marked enhancement in some but not all microextensions, the C-terminal fragment of moesin co-distributes with filamentous actin consistent with its actin-binding activity. By taking advantage of this property we studied the spontaneous protrusive activity of live NIH3T3 cells, expressing a fusion of GFP and the C-terminal domain of moesin.
        
        
          Results
          C-moesin-GFP localized to stress fibers and was enriched in actively protruding cellular regions such as filopodia or lamellipodia. This localization was reversibly affected by cytochalasin D. Multiple types of cytoskeletal rearrangements were observed that occurred independent of each other in adjacent regions of the cell surface. Assembly and disassembly of actin filaments occurred repeatedly within the same space and was correlated with either membrane protrusion and retraction, or no change in shape when microextensions were adherent.
        
        
          Conclusions
          Shape alone provided an inadequate criterion for distinguishing between retraction fibers and advancing, retracting or stable filopodia. Fluorescence imaging of C-moesin-GFP, however, paralleled the rapid and dynamic changes of the actin cytoskeleton in microextensions. Regional regulatory control is implicated because opposite changes occurred in close proximity and presumably independent of each other. This new and sensitive tool should be useful for investigating mechanisms of localized actin dynamics in the cell cortex.
Compound 525652: N,N-Dimethyl-N'-propyl-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N,N,4-trimethyl-N'-propylbenzenecarboximidamide. Molecular Formula: C13H20N2. Molecular Weight: 204.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hospital Inpatient Discharges (SPARCS De-Identified): Adult Prevention Quality Indicators (PQI) by County: Beginning 2009

This is one of two datasets that contain observed and expected rates for Agency for Healthcare Research and Quality Prevention Quality Indicators – Adult (AHRQ PQI) beginning in 2009. This dataset is at the county level. The Agency for Healthcare Research and Quality (AHRQ) Prevention Quality Indicators (PQIs) are a set of population based measures that can be used with hospital inpatient discharge data to identify ambulatory care sensitive conditions. These are conditions where 1) the need for hospitalization is potentially preventable with appropriate outpatient care, or 2) conditions that could be less severe if treated early and appropriately. All PQIs apply only to adult populations (over the age of 18 years).  The rates were calculated using Statewide Planning and Research Cooperative System (SPARCS) inpatient data and Claritas population information. 

The observed rates and expected rates for each AHRQ PQI is presented by either resident county (including a statewide total) or resident zip code (including a statewide total).
Insulin aspart

Novolog (insulin aspart) is a fast-acting insulin analog used to control blood sugar in people with diabetes. It's injected subcutaneously or intravenously, available in pens, syringes, and vials at 100 units/mL strength. Manufactured by Novo Nordisk, it's prescribed for managing type 1 or 2 diabetes. This information was generated using AI and is provided for informational and research purposes only.
Boston: Drug-Related Emergency Department Visits, 2004-2011 - Accidental Ingestions

Excel file with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving accidental ingestions in the Boston metropolitan area. This analytic category includes ED visits in which an individual accidentally or unknowingly used or was administered a prescription drug, over-the-counter medication, or dietary supplement. Drug-related accidental ingestion typically involves patients aged 5 and under.  This analytic category does not include drug misuse or abuse.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.