AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E401360-T1: [Translated] POLY(ETHERESTER) POLYOLS AND METHOD FOR THE PRODUCTION THEREOF

Preparation of poly (etherester)n (I) comprises: reaction of a mono or polycarboxylic acid ester containing hydroxy group with an alkyleneoxide to form mono or polycarboxylicacid ester with one or more polyether chains (II) by ring opening; and either transesterification of (II) to give (I) with hydroxy groups; or reaction of (II) with mono or polycarboxylicacidester containing free hydroxy group to give (I) with ester; or hydrolyzation of (II) with mono or polycarboxylic acid containing free hydroxy group to give (I) with carboxylic acid. Preparation of poly (etherester)n (I) comprises: reaction of a mono or polycarboxylic acid ester containing hydroxy group of formula ((R-O-(C=O)-) m-R-a-(-OH) n) with alkyleneoxide to form mono or polycarboxylicacid ester with one or more polyether chains (II), by ring opening, where the alkylene oxyaddition takesplace optionally in the presence of di- or polyols and dicarboxylic acid esters; and either transesterification of (II) to give (I) with hydroxy groups, where the transesterification takes place optionally by the addition of di- or polyols, diol and dicarboxylic acids, dicarboxylic acid derivatives, monocarboxylic acid esters or monocarboxylic containing di- or polyols or hydroxy groups; or reaction of (II) with mono or polycarboxylicacidester containing free hydroxy group to give (I) with ester; or hydrolyzation of (II) with mono or polycarboxylic acid containing free hydroxy group to give (I) with carboxylic acid. R : monovalent aryl-, alkyl-, aralkyl-, alkenyl- or alkynyl- radical; and R-a : bivalent aryl-, alkyl-, aralkyl-, alkenyl- or alkynyl- radical. Provided that: if m is 1, then n is1; or if m is >= 2, then n is 1; or if n is >= 2, then m is1. Independent claims are included for: (1) a poly(etherester), which is prepared by the above procedure; and (2) use of (I) for the preparation of polyurethane materials.
Antigen-specific cytometry

From its origins in the 16thcentury, microscopy has allowed the cell, as the basic unit of eukaryotic life and disease, to be identified and analyzed. Today, quantitative cytometric technologies, either microscope based or flow cytometric, are the most powerful tools to analyze the proliferation, physiology and differentiation of cells generally, and are particularly useful in immunopathology. In combination with monoclonal antibodies (which recognize specific gene products) conjugated to sensitive fluorescent dyes, cell types can be identified according to the genes they express. They can also be isolated using either fluorescence-activated cell sorting (FACS) or magnetic cell sorting (MACS). In the past 20 years, immunofluorescence-based cytometry and cell sorting have become 'state of the art' technologies, mostly serving to identify subsets of lymphocytes and systemic changes in the immune system. Although it is certainly of value for diagnosis and analysis of immunopathology, cytometry did have one major limitation; except in a few experimental situations, it was not possible to focus analysis on those lymphocytes that specifically recognize the relevant antigens in a normal or pathological immune reaction. This drawback has recently been overcome both for B and T lymphocytes, using antigen to identify the cells. Today, a number of exciting new technologies make it possible to analyze and isolate specifically those lymphocytes that are directly involved in the immune reaction to given antigens. These advances will spur research in arthritis considerably.
National Tables

Data tables consisting of Excel files with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011, for drug-related emergency department visits for the Nation. Tables are provided for 10 topics (\"analytic categories\") which are defined in the \"Guide to Drug Abuse Warning Trend Tables,\" a separate document.   Each table includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol. Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology. Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.
Compound 526401: 2-Bromo,1,3,8,9-tetrachloro-dibenzo-dioxin

Chemical compound data from PubChem database. IUPAC Name: 2-bromo-1,3,8,9-tetrachlorodibenzo-p-dioxin. Molecular Formula: C12H3BrCl4O2. Molecular Weight: 400.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526904: 2-Butoxyethyl TMS ether

Chemical compound data from PubChem database. IUPAC Name: 2-butoxyethoxy(trimethyl)silane. Molecular Formula: C9H22O2Si. Molecular Weight: 190.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400714-T1: [Translated] SWIMMING POOL COVER CONSISTING OF PROFILES

Chemical patent from PubChem database. Patent Number: AT-E400714-T1. Title: Novel Pharmaceutical Composition. Filing Date: 1997-09-09. Inventors: Kim, Young-Soo, Taylor, Elizabeth. Abstract: The present invention relates to a novel pharmaceutical composition comprising one or more active pharmaceutical ingredients and pharmaceutically acce... IPC Classifications: C07D, A61K, A61P. This patent covers 28 claims related to 2 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Prochlorperazine maleate

Prochlorperazine Maleate is a prescription medication used to treat nausea, vomiting, and certain mental health conditions like schizophrenia. Available as oral tablets in 5mg and 10mg strengths, it's manufactured by Amneal Pharmaceuticals NY LLC under ANDA216598. This generic drug belongs to the phenothiazine class. This information was generated using AI and is provided for informational and research purposes only.
Compound 528467: 1-Tridecene, 4,8,12-trimethyl

Chemical compound data from PubChem database. IUPAC Name: 4,8,12-trimethyltridec-1-ene. Molecular Formula: C16H32. Molecular Weight: 224.42. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Table 17. Alcohol Dependence or Abuse in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 17. Alcohol Dependence or Abuse in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Compound 527544: D-(+)-Turanose, octakis(trimethylsilyl) ether

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[[2,4,5-tris(trimethylsilyloxy)-3-[3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]silane. Molecular Formula: C36H86O11Si8. Molecular Weight: 919.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528626: N-ethyl-2,2-dimethylpropanamide

Chemical compound data from PubChem database. IUPAC Name: N-ethyl-2,2-dimethylpropanamide. Molecular Formula: C7H15NO. Molecular Weight: 129.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
ANA Objective Progress Report

The ANA Objective Progress Rreport collects data on project status on all funded objectives and activities and tracks the progress of the project impact indicators.

<b>Units of Response: </b>ANA Grantees

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>Yes

<b>COVID-19 Data: </b>Unavailable

<b>Periodicity: </b>Unavailable

<b>SORN: </b>Not Applicable

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Unavailable

<b>Equity Indicators: </b>Indigenous Population

<b>Granularity: </b>Grant

<b>Spatial: </b>United States

<b>Geocoding: </b>Unavailable
Compound 529336: 1H-Imidazole, 2-methyl-1-propyl

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-1-propylimidazole. Molecular Formula: C7H12N2. Molecular Weight: 124.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Effect of Interlukin-1β on proliferation of gastric epithelial cells in culture

Background
          Helicobacter pylori is the main risk factor for the development of non-cardia gastric cancer. Increased proliferation of the gastric mucosa is a feature of H. pylori infection. Mucosal interkeukin-1β production is increased in H. pylori infection and IL-1β genotypes associated with increased pro-inflammatory activity are risk factors for the development of gastric cancer. The effect of IL-1β on gastric epithelial cell proliferation has been examined in this study.
        
        
          Methods
          AGS cells were cultured with IL-1β. DNA synthesis was assed by [3H]thymidine incorporation and total viable cell numbers by MTT assay.
        
        
          Results
          IL-1β dose dependently increased DNA synthesis and cell numbers. The enhanced proliferation was blocked by interleukin-1 receptor antagonist. Addition of neutralising antibody to GM-CSF reduced IL-1β-stimulated proliferation by 31 ± 4 %. GM-CSF alone significantly stimulated proliferation. Addition or neutralisation of IL-8 had no effect on basal or IL-1β-stimulated proliferation. The tyrosine kinase inhibitor genistein completely blocked IL-1β-stimulated proliferation and inhibition of the extracellular signal related kinase pathway with PD 98059 inhibited IL-1β stimulated proliferation by 58 ± 5 %.
        
        
          Conclusions
          IL-1β stimulates proliferation in gastric epithelial cells. Autocrine stimulation by GM-CSF contributes to this proliferative response. Signalling via tyrosine kinase activity is essential to the mitogenic response to IL-1β. The extracellular signal related kinase pathway is involved in, but not essential to downstream signalling. IL-1β may contribute to the hyperproliferation seen in H. pylori- infected gastric mucosa, and be involved in the carcinogenic process.
Tumor necrosis factor-α and muscle wasting: a cellular perspective

Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness in inflammatory disease. Despite its potential importance in muscle pathology, the direct effects of TNF-α on skeletal muscle have remained undefined until recently. Studies of cultured muscle cells indicate that TNF-α disrupts the differentiation process and can promote catabolism in mature cells. The latter response appears to be mediated by reactive oxygen species and nuclear factor-κB which upregulate ubiquitin/proteasome activity. This commentary outlines our current understanding of TNF-α effects on skeletal muscle and the mechanism of TNF-α action.
Compound 526725: 2-(2-(2-decyloxy-ethoxy)-ethoxy)-ethanol, TFA

Chemical compound data from PubChem database. IUPAC Name: 2-[2-(2-decoxyethoxy)ethoxy]ethyl 2,2,2-trifluoroacetate. Molecular Formula: C18H33F3O5. Molecular Weight: 386.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Cross-sectional study of morbidity, morbidity-associated factors and cost of treatment in Ngaoundere, Cameroon, with implications for health policy in developing countries and development assistance policy

Background
          In a population-based epidemiological study in Ngaoundere, Cameroon, we studied cross-sectional child morbidity and the cost of necessary investigation and treatment.
        
        
          Methods
          Three teams of two to three health workers visited haphazardly selected households in all major housing quarters. We asked permission to enter for a health survey. Children with cough, fever or weight loss as well as sick adults were offered free-of-charge local hospital examination and treatment.
        
        
          Results
          From 177 households with 1777 persons, 51 (2.9%) persons were referred. Thirty-five of them had an undiagnosed disease threatening individual health and in many cases also public health. Seven were hospitalised, including three adults with tuberculosis. Malnutrition was diagnosed in nine small children. Four patients had AIDS, seven had malaria. Average total cost for ambulant patients was 15 USD, for hospitalised patients 110 USD.
          In the households, almost half of the women 16–50 years of age had no schooling. Two per cent of women and nine per cent of men were daily smokers. Coughing children were more likely than non-coughing children to live in a household with at least one smoker (OR = 3.58, 95% CI 1.72 to 7.46), and they generally lived in more poor households (P = 0.018). Twelve of 16 children with weight loss were referred from households with a high poverty score.
        
        
          Conclusions
          Adult smoking and poverty affect children's health. The cost of hospitalisation or long-lasting therapy is beyond the means of most ordinary families. Diseases with severe consequences for public health, like tuberculosis, AIDS and malaria should have national programs with free, decentralised examination and treatment. Access to generic drugs is important. A major educational effort is needed to improve public health.
CCWIS Data Quality Biennial Reviews

A discussion on CCWIS biennial reviews and data quality plans, including an overview of the relevant federal regulations, insights from recent state technical assistance monitoring reviews, and strategies on implementing a biennial review process.  This webinar includes presenters from state child welfare agencies who discuss their biennial review process, lessons learned, and how the reviews affected data quality.

Audio Description Version

Metadata-only record linking to the original dataset. Open original dataset below.
Efficacy of universal masking for source control and personal protection from simulated respiratory aerosols in a room

Masks block aerosols produced during coughs and exhalations (“source control”). Masks also slow and deflect cough and exhalation airflows, which changes the dispersion of aerosols. Factors such as the directions in which people are facing (orientation) and separation distance also affect aerosol dispersion. However, it is not clear how masking, orientation, and distance interact. We placed a respiratory aerosol simulator (“source”) and a breathing simulator (“recipient”) in a chamber and measured aerosol concentrations for different combinations of masking, orientation, and separation distance. When the simulators were front-to-front during coughing, masks reduced the 15-minute mean aerosol concentration at the recipient by 92% (p < 0.0001) at 0.9 and 1.8 m separation. When the simulators were side-by-side, masks reduced the concentration by 81% at 0.9 m and 78% at 1.8 m (p < 0.0001 for both). During breathing, masks reduced the aerosol concentration by 66% when front-to-front (p = 0.0056) and 76% when side-by-side (p < 0.0001) at 0.9 m. Similar results were seen at 1.8 m. When the simulators were unmasked, changing the orientations from front-to-front to side-by-side reduced the cough aerosol concentration by 59% at 0.9 m and 60% at 1.8 m (p < 0.0001 for both). When both simulators were masked, changing the orientations did not significantly change the concentration at either distance during coughing or breathing. Increasing the distance between the simulators from 0.9 m to 1.8 m during coughing reduced the aerosol concentration by 25% when no masks were worn (p < 0.0001) but had little effect when both simulators were masked (4% decrease, p = 0.7090). During breathing, when neither simulator was masked, increasing the separation reduced the concentration by 13%, which approached significance (p = 0.0737), while the change was not significant when both source and recipient were masked (8% decrease, p = 0.3235). Our results suggest that universal masking reduces exposure to respiratory aerosol particles regardless of the orientation and separation distance between the source and recipient.
Autologous stem-cell transplantation in refractory autoimmune diseases after

Autoimmune diseases that are resistant to conventional treatment cause severe morbidity and even mortality. In the present study we demonstrate that complete remissions can be achieved in refractory polychondritis and systemic lupus erythematosus (SLE), even at advanced stage, with the use of autologous stem-cell transplantation (SCT). Remissions persisted after reconstitution of the immune system. In the treatment of advanced systemic sclerosis (SSc), stable disease may be achieved with autologous SCT.
Patent AT-E401477-T1: [Translated] SWIMMING POOL COVER COMPRISING THE ASSEMBLY OF SEVERAL SLATS OF VARIABLE LENGTH AND SLAMS OF THE SWIMMING POOL COVER

The cover has an assembly of slats floating on a surface of the water contained in a swimming pool. Each of the slats has a slat body (2) cooperating, at one of its ends, with a movable end piece (1) by sliding interlocking connections, where the pieces allow to vary the lengths of the slats. The slat bodies constitute male units and the pieces constitute female units in the connection. The pieces have sections with complementary projecting parts (11) sliding into projecting parts (23) of the slat bodies.
2022 Methodological Summary And Definitions

Use this summary report to properly interpret 2022 NSDUH estimates related to substance use, mental health, and treatment. The report accompanies theannual detailed tablesand covers overall methodology, key definitions for measures and terms used in 2022 NSDUH reports and tables, and selected analyses of the measures and how they should be interpreted.The report is organized into five chapters:Introduction.Description of the survey, including information about the sample design, data collection procedures and questionnaire changes, and key aspects of data processing such as development of the analysis weights.Technical details on the statistical methods and measurement, such as suppression criteria for unreliable estimates, statistical testing procedures, revised estimates for 2021 to account for data collection mode, and issues around selected substance use and mental health measures.Special topics related to prescription psychotherapeutic drugs.Description of other sources of data on substance use and mental health issues in the United States, including data sources for populations outside the NSDUH target population.An appendix covers key definitions used in NSDUH reports and tables.
Ezetimibe and simvastatin

Ezetimibe and Simvastatin is a prescription medication that combines two drugs to lower cholesterol levels in the blood. Ezetimibe reduces cholesterol absorption from food, while simvastatin blocks cholesterol production in the liver. Available as oral tablets in strengths like 10mg/10mg, 10mg/20mg, 10mg/40mg, and 10mg/80mg, it's used to treat high cholesterol and prevent heart disease. Consult a doctor for proper use and side effects. This information was generated using AI and is provided for informational and research purposes only.
Compound 526557: 3,6,9,12,15,18-Hexaoxaicosan-1-ol

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-[2-(2-ethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Molecular Formula: C14H30O7. Molecular Weight: 310.38. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Detroit-Warren-Livonia, MI

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Detroit-Warren-Livonia, MI metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for the Detroit-Warren-Livonia metro area, Michigan, and the U.S. overall.
Compound 526247: 1,2,6,7-Tetrabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,6,7-tetrabromodibenzofuran. Molecular Formula: C12H4Br4O. Molecular Weight: 483.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526140: Pentanoic acid, 4-hydroxy-2-propyl, bis-TMS, # 1

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-propyl-4-trimethylsilyloxypentanoate. Molecular Formula: C14H32O3Si2. Molecular Weight: 304.57. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401778-T1: [Translated] PROTECTIVE DEVICE FOR A MOWER

An agricultural mower 10 having a support frame 2, means for attaching the support frame to a propelling vehicle, at least one mowing device 3 mounted on the support frame 2, a cover 1 overlying at least part of the mowing device 3, and a flexible curtain 4 depending from at least part of the outer periphery of the cover 1 so as partly to surround the mowing device 3:  characterised in that the cover 1 comprises an assembly of upper and lower protective sheets 1a, 1b which are spaced apart from each other and which are connected together along two opposed edge regions 1c,1d.
Compound 525611: N,N-Dimethyl-N'-benzyl-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-benzyl-4-chloro-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H17ClN2. Molecular Weight: 272.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
San Francisco – SF Div: Drug-Related Emergency Department Visits, 2004-2011 - All Visits

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits in the San Francisco division of the San Francisco metropolitan area, covering 2004-2011. File includes all drug-related ED visits that are reportable to DAWN without regard for the reason for the visit or the specific drugs involved. It includes visits involving all forms of drug misuse or abuse plus visits resulting from adverse reaction, accidental ingestion, suicide attempts, and visits where patients were seeking detoxification services. These estimates are useful for looking at overall levels of drug involvement in ED visits.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.