AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 527146: Bromobutide-debromo

Chemical compound data from PubChem database. IUPAC Name: 3,3-dimethyl-N-(2-phenylpropan-2-yl)butanamide. Molecular Formula: C15H23NO. Molecular Weight: 233.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Optimizing antibiotic therapy in the intensive care unit setting

Antibiotics are one of the most common therapies administered in the intensive care unit setting. In addition to treating infections, antibiotic use contributes to the emergence of resistance among pathogenic microorganisms. Therefore, avoiding unnecessary antibiotic use and optimizing the administration of antimicrobial agents will help to improve patient outcomes while minimizing further pressures for resistance. This review will present several strategies aimed at achieving optimal use of antimicrobial agents. It is important to note that each intensive care unit should have a program in place which monitors antibiotic utilization and its effectiveness. Only in this way can the impact of interventions aimed at improving antibiotic use (e.g. antibiotic rotation, de-escalation therapy) be evaluated at the local level.
2014 CMHS Uniform Reporting System (URS) Table for Minnesota

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Minnesota. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
TANF High Performance Measures

The TANF program was reauthorized under the Deficit Reduction Act of 2005. The statute eliminated the funding for the High Performance Bonus under section 403 (a)(4) of the Social Security Act. Nevertheless, the Department was required under section 413(d) to annually rank state performance in moving TANF recipients into private sector employment.

<b>Units of Response: </b>State TANF Programs

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>No

<b>Periodicity: </b>Annual

<b>Demographic Indicators: </b>Unavailable

<b>SORN: </b>https://www.federalregister.gov/documents/2015/04/02/2015-07440/privacy-act-of-1974-system-of-records-notice

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Unavailable

<b>Granularity: </b>State

<b>Spatial: </b>United States

<b>Geocoding: </b>State
Patent AT-E400011-T1: [Translated] MEASURING PROBE FOR A MACHINE TOOL CONFIGURABLE BY BENDING THE PROBE

A probe 10 has internal circuitry capable of operating in a plurality of different modes, for example a variety of filter modes and turn off modes. A method of operating such a probe is described in which deflection of the stylus is used to set the mode of operation. In one embodiment, the probe has a workpiece-contacting stylus 11 mounted on a seat from which it is deflectable.
Dependence, Abuse, and Treatment Tables (Prevalence Estimates) - 5.1 to 5.56

These detailed tables present totals and prevalence estimates of substance dependence/abuse and treatment need/receipt from the 2010 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs, marijuana, cocaine, heroin, hallucinogens, inhalants, and the nonmedical use of prescription-type pain relievers, tranquilizers, stimulants, and sedatives, and alcohol. Results are provided by age group, gender, race/ethnicity, education level, employment status, and geographic area. Comparisons are made between 2010 and 2009.
Deer Tick Surveillance: Adults (Oct to Dec) excluding Powassan virus: Beginning 2008

This dataset provides the results from collecting and testing adult deer ticks, also known as blacklegged ticks, or by their scientific name <i>Ixodes scapularis</i>. Collection and testing take place across New York State (excluding New York City) from October to December, when adult deer ticks are most commonly seen. 

Adult deer ticks are individually tested for different bacteria and parasites, which includes the bacteria responsible for Lyme disease. These data should simply be used to educate people that there is a risk of coming in contact with ticks and tick-borne diseases. 

These data only provide adult tick infections at a precise location and at one point in time. Both measures, tick population density and percentage, of ticks infected with the specified bacteria or parasite can vary greatly within a very small area and within a county. These data should not be used to broadly predict disease risk for a county.

Further below on this page you can find links to tick prevention tips, a video on how to safely remove a tick, and more datasets with tick testing results. Interactive charts and maps provide an easier way to view the data.
Program Instruction (PI-18-05)

This Program Instruction (PI) provides guidance to state, territorial and tribal title IV-E agencies on the actions required to apply for one-time funding to support the development, enhancement or evaluation of kinship navigator programs. These are federal fiscal year (FY) 2018 funds, provided as part of the Consolidated Appropriations Act of 2018, enacted March 23, 2018, and must be awarded before September 30, 2018.

Metadata-only record linking to the original dataset. Open original dataset below.
The diversity of microorganisms associated with

Background
          Molecular biological techniques are dramatically changing our view of microbial diversity in almost any environment that has so far been investigated. This study presents a systematic survey of the microbial diversity associated with a population of Acromyrmex leafcutter ants. In contrast to previous studies on social insects, which targeted specific groups of symbionts occurring in the gut (termites, Tetraponera ants) or in specialised cells (Camponotus ants) the objective of our present study was to do a total screening of all possible micro-organisms that can be found inside the bodies of these leafcutter ants.
        
        
          Results
          We amplified, cloned and sequenced SSU rRNA encoding gene fragments from 9 microbial groups known to have insect-associated representatives, and show that: (1) representatives of 5 out of 9 tested groups are present, (2) mostly several strains per group are present, adding up to a total of 33 different taxa. We present the microbial taxa associated with Acromymex ants in a phylogenetic context (using sequences from GenBank) to assess and illustrate to which known microorganisms they are closely related. The observed microbial diversity is discussed in the light of present knowledge on the evolutionary history of Acromyrmex leafcutter ants and their known mutualistic and parasitic symbionts.
        
        
          Conclusions
          The major merits of the screening approach documented here is its high sensitivity and specificity, which allowed us to identify several microorganisms that are promising candidates for further study of their interactions with Acromyrmex leafcutter ants or their gardens.
Patent AT-E400892-T1: [Translated] PRODUCTION PROCESS FOR CMOS SEMICONDUCTOR COMPONENTS WITH SELECTABLE GATE THICKNESS

The present invention discloses a method for obtaining layers, manufactured in the same device material, with different thickness or layer height. A specific example of such a process is a CMOS process comprising nMOS and pMOS devices with different gate electrode thickness. After forming the device material layer or gate electrode layer (2) disposable parts (4) are formed in selected regions (3) of this device layer (2). Preferably disposable parts are formed by doping the selected regions (3) to the required depth d. The as-deposited thickness t of this device (2) layer will be adjusted or modulated after the patterning of the individual devices by removing the disposable parts (4). <IMAGE>
Compound 526013: Dopamine, N-DTFMB-TMS

Chemical compound data from PubChem database. IUPAC Name: N-[2-[3,4-bis(trimethylsilyloxy)phenyl]ethyl]-3,5-bis(trifluoromethyl)benzamide. Molecular Formula: C23H29F6NO3Si2. Molecular Weight: 537.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Gadobutrol

Gadobutrol is a prescription intravenous contrast agent used to enhance magnetic resonance imaging (MRI) scans, helping doctors visualize body structures more clearly. Manufactured by Fresenius Kabi USA, LLC, it's available in solution form with a concentration of 604.72 mg/mL in vials of 2 mL, 7.5 mL, 10 mL, or 15 mL. This gadolinium-based drug works by improving MRI contrast for better diagnosis. This information was generated using AI and is provided for informational and research purposes only.
Compound 529202: Benzoic acid, 4-bromo, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 4-bromobenzoate. Molecular Formula: C10H13BrO2Si. Molecular Weight: 273.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Survey of Substance Abuse Treatment Services: State Profiles 2010

The 2010 National Survey of Substance Abuse Treatment Services (N-SSATS) is an annual survey of facilities providing substance abuse treatment. The N-SSATS, conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), is designed to collect data on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse facilities (both public and private) throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.
Mimicking microbial 'education' of the immune system: a strategy to revert the epidemic trend of atopy and allergic asthma?

Deficient microbial stimulation of the immune system, caused by hygiene, may underly the atopy and allergic asthma epidemic we are currently experiencing. Consistent with this 'hygiene hypothesis', research on immunotherapy of allergic diseases also centres on bacteria-derived molecules (eg DNA immunostimulatory sequences) as adjuvants for allergen-specific type 1 immune responses. If we understood how certain microbes physiologically 'educate' our immune system to interact safely with environmental nonmicrobial antigens, we might be able to learn to mimic their beneficial actions. Programmed 'immunoeducation' would consist of safe administration, by the correct route, dose and timing, of those microbial stimuli that are necessary to 'train' the developing mucosal immune system and to maintain an appropriate homeostatic equilibrium between its components. Overall, this would result in a prevention of atopy that is not limited to certain specific allergens. Although such a strategy is far beyond our present potential, it may in principle revert the epidemic trend of atopy and allergic asthma without jeopardizing the fight against infectious diseases.
Therapeutic utility of aspirin in the

Background
          In recent years it has become evident that nonsteroidal anti-inflammatory drugs, in particular aspirin represent a potential class of cancer chemotherapeutic agents. Despite the wealth of knowledge gained from epidemiological, clinical and animal studies, the effectiveness of aspirin to treat established gastrointestinal cancer has not been determined. The present study examines the ability of aspirin to treat established polyposis in Min/+ mice.
        
        
          Methods
          Min/+ mice with established polyposis were treated orally once daily from 12–16 weeks of age with either drug vehicle or aspirin (25 mg/kg). Upon completion of treatment, the number, location and size of intestinal tumours was determined. Additional variables examined were the number of apoptotic cells within tumours and COX activity.
        
        
          Results
          Administration of aspirin for 4 weeks to Min/+ mice produce no effect on tumour number compared to vehicle-treated Min/+ mice (65 ± 8 vs. 63 ± 9, respectively). In addition, aspirin had no effect on tumour size or location. However, aspirin treatment produced a greater than 2-fold (p < 0.05) increase in the number of apoptotic positive cells within tumours and significantly decreased hepatic PGE2 content.
        
        
          Conclusions
          Aspirin was found to have no effect on tumour number and size when administered to Min/+ mice with established polyposis. The findings in the present study call in to question the utility of aspirin as a stand-alone treatment for established GI cancer. However, aspirin's ability to significantly promote apoptosis may render it suitable for use in combinatorial chemotherapy.
Patent AT-E400727-T1: [Translated] FIRE PROTECTION INSULATION DEVICE

The system is assembled of a suitable number of insulation panels and holding rails (3,11) with specifically shaped intersections. One of the rails (3) forming an intersection has a flat central segment provided with two rectangular extensions (6) opposite each other. A step (14) is located between the flat center and the extensions (6) matching the shape of the outer ends (16) of two rails (11) meeting at the central segment. Slots facilitate the release of moisture.
Compound 527122: 1,3-Dichloro-dibenzothiophene

Chemical compound data from PubChem database. IUPAC Name: 1,3-dichlorodibenzothiophene. Molecular Formula: C12H6Cl2S. Molecular Weight: 253.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526721: 2-(2-(2-(2-nonyloxy-ethoxy)-ethoxy)-ethoxy)-ethanol, TFA

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-(2-nonoxyethoxy)ethoxy]ethoxy]ethyl 2,2,2-trifluoroacetate. Molecular Formula: C19H35F3O6. Molecular Weight: 416.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Illicit Drug Use Tables  (Prevalence Estimates) - 1.1 to 1.92

These detailed tables are population illicit drug use totals and prevalence estimates from the 2011 National Survey on Drug Use and Health (NSDUH). Illicit drugs include marijuana, cocaine, crack, heroin, hallucinogens, inhalants, and the nonmedical use of prescription-type psychotherapeutics, including pain relievers, tranquilizers, stimulants, and sedatives. Results are provided for lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area. Comparisons are made between 2011 and 2010.
Compound 530228: Pyridoxamine, TMS

Chemical compound data from PubChem database. IUPAC Name: 1-[2-methyl-3-trimethylsilyloxy-5-(trimethylsilyloxymethyl)pyridin-4-yl]-N-trimethylsilylmethanamine. Molecular Formula: C17H36N2O2Si3. Molecular Weight: 384.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Estimates of Drug-Related Emergency Department Visits, 2004-2011 - Accidental Ingestions

Excel file with national estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving accidental ingestions. This analytic category includes ED visits in which an individual accidentally or unknowingly used or was administered a prescription drug, over-the-counter medication, or dietary supplement. Drug-related accidental ingestion typically involves patients aged 5 and under.  This analytic category does not include drug misuse or abuse.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.
Compound 529460: 5,8a-Dimethyl-3-prop-1-en-2-yl-2,3,4,4a,7,8-hexahydronaphthalen-1-one

Chemical compound data from PubChem database. IUPAC Name: 5,8a-dimethyl-3-prop-1-en-2-yl-2,3,4,4a,7,8-hexahydronaphthalen-1-one. Molecular Formula: C15H22O. Molecular Weight: 218.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Directory of Drug and Alcohol Abuse Treatment Facilities 2011

The National Directory of Drug and Alcohol Abuse Treatment Programs 2011 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 2010 National Survey of Substance Abuse Treatment Services (N-SSATS). The information about each facility that appears in this directory was provided by that facility in response to the 2010 N-SSATS. The Substance Abuse and Mental Health Services Administration (SAMHSA) conducts the N-SSATS annually.
Compound 527325: 4-butyl-3-methoxy-2-(4-methoxyphenyl)-1H-pyrazol-5-one

Chemical compound data from PubChem database. IUPAC Name: 4-butyl-3-methoxy-2-(4-methoxyphenyl)-1H-pyrazol-5-one. Molecular Formula: C15H20N2O3. Molecular Weight: 276.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Behavioral Risk Factor Surveillance Survey: 2016

The Behavioral Risk Factor Surveillance System (BRFSS) is an annual statewide telephone surveillance system designed by the Centers for Disease Control and Prevention (CDC). BRFSS monitors modifiable risk behaviors and other factors contributing to the leading causes of morbidity and mortality in the population. New York State's BRFSS sample represents the non-institutionalized adult household population, aged 18 years and older. Although the overall number of respondents in the BRFSS is more than sufficiently large for statistical inference purposes, subgroup analyses can lead to estimates that are unreliable. Interpreting and reporting weighted numbers that are based on a small, unweighted number of respondents can mislead the reader into believing that a given finding is much more precise than it actually is. The BRFSS follows a rule of not reporting or interpreting percentages based upon a denominator of fewer than 50 respondents (unweighted sample). Both a csv and sas data files are available. For more information, check out http://www.health.ny.gov/statistics/brfss/.
Detection of malaria parasites by nested PCR in south-eastern, Iran: Evidence of highly mixed infections in Chahbahar district

Background
          Rapid diagnosis and correct treatment of cases are the main objectives of control programs in malaria-endemic areas.
        
        
          Methods and results
          To evaluate these criteria and in a comparative study, blood specimens were collected from 120 volunteers seeking care at the Malaria Health Center in Chahbahar district. One hundred and seven out of 120 Giemsa-stained slides were positive for malaria parasites by microscopy. Eighty-four (70%) and 20 (16.7%) were identified as having only Plasmodium vivax and Plasmodium falciparum infections, respectively, while only 3 (2.5%) were interpreted as having mixed P. vivax-P. falciparum infections.
          The target DNA sequence of the 18S small sub-unit ribosomal RNA (ssrRNA) gene was amplified by Polymerase Chain Reaction (PCR) and used for the diagnosis of malaria in south-eastern Iran. One hundred twenty blood samples were submitted and the results were compared to those of routine microscopy. The sensitivity of PCR for detection of P. vivax and P. falciparum malaria was higher than that of microscopy: nested PCR detected 31 more mixed infections than microscopy and parasite positive reactions in 9 out of the 13 microscopically negative samples. The results also confirmed the presence of P. vivax and P. falciparum.
        
        
          Conclusions
          These results suggest that, in places where transmission of both P. vivax and P. falciparum occurs, nested PCR detection of malaria parasites can be a very useful complement to microscopical diagnosis.
Pro/con clinical debate: Are steroids useful in the management of patients with septic shock?

Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of reasons. To begin with, evidence may not exist to answer the clinical question. Second, when there is evidence it may not be applicable to the patient in question or the clinician may be reluctant to apply it to the patient based on a number of secondary issues such as costs, premorbid condition or possible complications. Finally, emotions are often highly charged when caring for patients that have a significant chance of death, and care-givers as well as families are frequently prepared to take chances on a therapy whose benefit is not entirely clear. Steroid use in septic shock is an example of a therapy that makes some sense but has conflicting support in the literature. In this issue of Critical Care Forum, the two sides of this often heated debate are brought to the forefront in an interesting format.
Compound 528093: Carbamic acid, 4-methylphenyl, octyl ester

Chemical compound data from PubChem database. IUPAC Name: octyl N-(4-methylphenyl)carbamate. Molecular Formula: C16H25NO2. Molecular Weight: 263.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526871: 2-(2-(2-Isobutoxy-ethoxy)-ethoxy)-ethoxy)-ethyl trifluroacetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-(2-methylpropoxy)ethoxy]ethoxy]ethoxy]ethyl 2,2,2-trifluoroacetate. Molecular Formula: C14H25F3O6. Molecular Weight: 346.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.