AndreaBozzo/ceres-open-data-index huggingface dataset:
National Directory of Drug and Alcohol Abuse Treatment Facilities - 1975

The National Directory of Drug and Alcohol Abuse Treatment Programs 1975 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 1974 National Survey of Substance Abuse Treatment Services (N-SSATS). The information about each facility that appears in this directory was provided by that facility in response to the 1974 N-SSATS. The Substance Abuse and Mental Health Services Administration (SAMHSA) conducts the N-SSATS annually.
Magnetic stimulation for non-homogeneous biological structures

Background
          Magnetic stimulation has gained relatively wide application in studying nervous system structures. This technology has the advantage of reduced excitation of sensory nerve endings, and hence results in quasi-painless action. It has become clinically accepted modality for brain stimulation. However, theoretical and practical solutions for assessment of induced current distribution need more detailed and accurate consideration.
          Some possible analyses are proposed for distribution of the current induced from excitation current contours of different shape and disposition. Relatively non-difficult solutions are shown, applicable for two- and three-dimensional analysis.
        
        
          Methods
          The boundary conditions for field analysis by the internal Dirichlet problem are introduced, based on the vector potential field excited by external current coils. The feedback from the induced eddy currents is neglected. Finite element modeling is applied for obtaining the electromagnetic fields distribution in a non-homogeneous domain.
        
        
          Results
          The distributions were obtained in a non-homogeneous structure comprised of homogeneous layers. A tendency was found of the induced currents to follow paths in lower resistivity layers, deviating from the expected theoretical course for a homogeneous domain. Current density concentrations occur at the boundary between layers, suggesting the possibility for focusing on, or predicting of, a zone of stimulation.
        
        
          Conclusion
          The theoretical basis and simplified approach for generation of 3D FEM networks for magnetic stimulation analysis are presented, applicable in non-homogeneous and non-linear media. The inconveniences of introducing external excitation currents are avoided. Thus, the possibilities are improved for analysis of distributions induced by time-varying currents from contours of various geometry and position with respect to the medium.
Patent AT-E399746-T1: [Translated] METHOD FOR IMPROVING THE BURNING RATE AND FLAMMABILITY OF ALUMINUM PROpellant PARTICLES AND ALUMINUM PROpellant MODIFIED

A method of improving the burn rate and ignitability of aluminium fuel particles, and a thus modified aluminium fuel for use in propellant and explosive compositions and pyrotechnic charges. Aluminium fuel particles are treated with an aqueous solution of hydrofluoric acid and a fluoride and/or complex fluoride salt of an alkali metal and/or alkaline earth metal to form a surface layer of a fluoride complex bound to the aluminium fuel particle.
Compound 527153: 2,2,2-Trichloroethyl butyrate

Chemical compound data from PubChem database. IUPAC Name: 2,2,2-trichloroethyl butanoate. Molecular Formula: C6H9Cl3O2. Molecular Weight: 219.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart

Background
          Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported that cardiac cardiolipin levels, MLCL AT and cardiolipin synthase activities were all elevated in rats made hyperthyroid by thyroxine treatment. In this study, we examined if cardiac mitochondrial MLCL AT activity was dependent upon the biosynthesis and level of cardiolipin in the heart. Rat heart mitochondrial MLCL AT activity was determined under conditions in which the levels of cardiac cardiolipin and cardiolipin synthase activity were either reduced or unaltered using four different disease models in the rat. In addition, these parameters were examined in a murine model of cardiac cell differentiation.
        
        
          Results
          In rats made hypothyroid by treatment with 6-n-propyl-2-thiouracil in the drinking water for 34 days, cardiac cardiolipin content was decreased 29% (p < 0.025) and this was associated with a 32% decrease (p < 0.025) in cardiolipin synthase and a 35% reduction (p < 0.025) in MLCL AT activities. Streptozotocin-induced diabetes or hyperinsulinemia in rats did not affect cardiac cardiolipin content nor MLCL AT and cardiolipin synthase activities. Finally, cardiolipin content, MLCL AT and cardiolipin synthase activities were unaltered during murine P19 teratocarcinoma cell differentiation into cardiac myocytes. In all models, phospholipase A2 activities were unaltered compared with controls.
        
        
          Conclusion
          We propose a general model in which the expression of MLCL AT activity is regulated in concert with the biosynthesis and level of cardiolipin in the heart.
Compound 527367: 18,22-Dimethyl-tetratriacontyl cyanide

Chemical compound data from PubChem database. IUPAC Name: 19,23-dimethylpentatriacontanenitrile. Molecular Formula: C37H73N. Molecular Weight: 532.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400587-T1: [Translated] ANTIBODIES DIRECTED AGAINST THE PROSTATE STEM CELL ANTIGEN (PSCA) AND THEIR USE

The invention provides isolated anti-prostate stem cell antigen (PSCA) antibodies that internalize upon binding to PSCA on a mammalian in vivo. The invention also encompasses compositions comprising an anti-PSCA antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-PSCA antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-PSCA antibodies. The invention encompasses a method of producing the anti-PSCA antibodies. Other aspects of the invention are a method of killing a PSCA-expressing cancer cell, comprising contacting the cancer cell with an anti-PSCA antibody and a method of alleviating or treating a PSCA-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-PSCA antibody to the mammal.
National Ambulatory Medical Care Survey Provider Component, 2023-2024, restricted-use data

The NAMCS Provider Survey Component focuses on the provider experience. No visit-level data were collected in 2023 nor 2024, only provider-level. Researchers can access restricted NAMCS Provider Survey Component data through the NCHS Research Data Center. Note that 2023 and 2024 were considered pilot years for the NAMCS Provider Survey Component. Consequently, these data are unweighted and will not allow for national estimates.  Two files are available—one for office-based physicians and one for physician associates.
2014 CMHS Uniform Reporting System (URS) Table for Oregon

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Oregon. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Ropivacaine hydrochloride

Ropivacaine Hydrochloride is a prescription local anesthetic used for epidural and infiltration injections to numb areas during surgery, labor, or pain management. It comes in injectable solutions with strengths of 2 mg/mL or 5 mg/mL, manufactured by Sagent Pharmaceuticals. This information was generated using AI and is provided for informational and research purposes only.
Compound 525247: N''-(4-ethoxy-phenyl)-N,N,N',N'-tetramethyl-guanidine

Chemical compound data from PubChem database. IUPAC Name: 2-(4-ethoxyphenyl)-1,1,3,3-tetramethylguanidine. Molecular Formula: C13H21N3O. Molecular Weight: 235.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
In-vivo evaluation of simultaneous administration of incompatible
		  drugs in a central venous catheter with a decreased port to port distance

Background:
          Multilumen catheters are commonly used in critically ill children.
				Their use, however, is associated with significant morbidity. We studied the
				simultaneous administration of incompatible drugs using a new triple-lumen
				catheter with decreased length and port to port distances.
        
        
          Methods:
          Ten domestic swine, 10–20 kg in weight, were divided into two
				groups of five. Total parenteral nutrition was administered through the distal
				port and phenytoin was administered as a bolus and as an infusion in each
				group. Samples were taken from two sites during the bolus and at 1, 5, and
				15 min during phenytoin infusion. Histograms were generated for particle size
				and concentration. Samples were also examined under the microscope for
				particles.
        
        
          Results:
          Histograms of particle size did not show any alteration of the
				histogram that would suggest particle size > 2 μm in diameter in the
				study or control samples. No particles were identified by phase microscope,
				light microscope, or Wright stain smear.
        
        
          Conclusions:
          The use of a triple-lumen catheter with a distance of 0.4cm
				between the proximal port and the medial port and 1.3 cm between the medial port
				and the distal port, for the in vivo simultaneous administration of
				incompatible solutions does not result in precipitates large enough to cause
				adverse clinical effects.
Program Instruction (PI-13-02)

This Program Instruction (PI) provides instruction on the availability of Federal Fiscal Year (FFY) 2013 Funds under the Community-Based Grants for the Prevention of Child Abuse and Neglect program created by Title II of the Child Abuse Prevention and Treatment Act (CAPTA) as amended by Public Law (P.L.) 111-320.

Metadata-only record linking to the original dataset. Open original dataset below.
Efficacy of SSH PCR in isolating differentially expressed genes

Background
          Suppression Subtractive Hybridization PCR (SSH PCR) is a sophisticated cDNA subtraction method to enrich and isolate differentially expressed genes. Despite its popularity, the method has not been thoroughly studied for its practical efficacy and potential limitations.
        
        
          Results
          To determine the factors that influence the efficacy of SSH PCR, a theoretical model, under the assumption that cDNA hybridization follows the ideal second kinetic order, is proposed. The theoretical model suggests that the critical factor influencing the efficacy of SSH PCR is the concentration ratio (R) of a target gene between two cDNA preparations. It preferentially enriches "all or nothing" differentially expressed genes, of which R is infinite, and strongly favors the genes with large R. The theoretical predictions were validated by our experiments. In addition, the experiments revealed some practical limitations that are not obvious from the theoretical model. For effective enrichment of differentially expressed genes, it requires fractional concentration of a target gene to be more than 0.01% and concentration ratio to be more than 5 folds between two cDNA preparations.
        
        
          Conclusion
          Our research demonstrated theoretical and practical limitations of SSH PCR, which could be useful for its experimental design and interpretation.
Palopegteriparatide

Yorvipath (palopegteriparatide) is a prescription medication injected under the skin to treat osteoporosis in certain adults. It works by mimicking parathyroid hormone to help build bone strength. Available in solution form with doses like 0.168 mg or 0.42 mg per cartridge. Manufactured by Ascendis Pharma, Endocrinology, Inc. This information was generated using AI and is provided for informational and research purposes only.
Glycopyrrolate

Glycopyrrolate is an injectable anticholinergic medication that blocks certain nerve signals to reduce secretions and treat conditions like bradycardia. Administered via intramuscular or intravenous injection at 0.2 mg/mL strength, it's available in multi-dose vials from Meitheal Pharmaceuticals Inc. (ANDA212802). This information was generated using AI and is provided for informational and research purposes only.
2012-2014 NSDUH Substate Region Shapefile

This report provides a guide to the development and presentation of 2012-2014 NSDUH substate estimates. A summary of the estimation methodology is included as well as sample sizes, response rates, and population estimates.This shapefile includes geographic boundaries of the 2012-2014 NSDUH substate regions along with prevalence rates, map group values, and the upper and lower bounds found in the map legends. It can be used for analysis and data display with Geographic Information Systems (GIS) software.
Splinting or surgery for carpal tunnel syndrome? Design of a randomized controlled trial [ISRCTN18853827]

Background
          Carpal tunnel syndrome is a common disorder, which can be treated with surgery or conservative options. However, there is insufficient evidence and no consensus among physicians with regard to the preferred treatment for carpal tunnel syndrome. Therefore, a randomized controlled trial is conducted to compare the short- and long-term efficacy of surgery and splinting in patients with carpal tunnel syndrome. An attempt is also made to avoid the (methodological) limitations encountered in earlier trials on the efficacy of various treatment options for carpal tunnel syndrome.
        
        
          Methods
          Patients of 18 years and older, with clinically and electrophysiologically confirmed idiopathic carpal tunnel syndrome, are recruited by neurologists in 13 hospitals. Patients included in the study are randomly allocated to either open carpal tunnel release or wrist splinting during the night for at least 6 weeks. The primary outcomes are general improvement, waking up at night and severity of symptoms (main complaint, night and daytime pain, paraesthesia and hypoesthesia). Outcomes are assessed up to 18 months after randomization.
Effects of de-industrialization on unemployment, re-employment, and work conditions in a manufacturing workforce

Background
          The purpose of this study was to investigate the impact of a 20-year process of de-industrialization in the British Columbia (BC) sawmill industry on labour force trajectories, unemployment history, and physical and psychosocial work conditions as these are important determinants of health in workforces.
        
        
          Methods
          The study is based on a sample of 1,885 respondents all of whom were sawmill workers in 1979, a year prior to commencement of de-industrialization and who were followed up and interviewed approximately 20 years later.
        
        
          Results
          Forty percent of workers, 64 years and under, were employed outside the sawmill sector at time of interview. Approximately one third of workers, aged 64 and under, experienced 25 months of more of unemployment during the study period. Only, 1.5% of workers were identified as a "hard core" group of long-term unemployed. Workers re-employed outside the sawmill sector experienced improved physical and psychosocial work conditions relative to those employed in sawmills during the study period. This benefit was greatest for workers originally in unskilled and semi-skilled jobs in sawmills.
        
        
          Conclusions
          This study shows that future health studies should pay particular attention to long-term employees in manufacturing who may have gone through de-industrialization resulting in exposures to a combination of sustained job insecurity, cyclical unemployment, and adverse physical and psychosocial work conditions.
Early Identification of Developmental Disabilities: Practical Tools For Professionals

This webinar, featuring Dr. Jacqueline Bertrand and Dr. Rebecca Wolf of the Centers for Disease Control and Prevention (CDC), describes programs and materials available from the CDC that can assist child welfare directors and providers with the identification of and referrals for children with developmental disabilities. It focuses on children with fetal alcohol spectrum disorders or autism spectrum disorders and highlights the CDC’s Learn the Signs Act Early program.

View Webinar (WMV – 55,241 KB)
View Transcript (PDF - 79.11 KB)
View Presentation Slides (PDF) (PDF - 1.47 MB)

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525096: 1,3-Dichloroisopropyl heptanoate

Chemical compound data from PubChem database. IUPAC Name: 1,2-dichloropropan-2-yl heptanoate. Molecular Formula: C10H18Cl2O2. Molecular Weight: 241.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Utilization Rates for Selected Medical Procedures in California Hospitals

The dataset contains 3 utilization rates (Cesarean Delivery Rate, Uncomplicated; Primary Cesarean Delivery Rate, Uncomplicated; Vaginal Birth After Cesarean Rate, Uncomplicated) for procedures performed in California hospitals. They are not related to the Let's Get Healthy California indicators. This dataset does not include procedures performed in outpatient settings. Different versions of AHRQ software were applied to different years. Specifically, 2019-2023 data were generated with Version 2024, while years prior to 2019 were generated with earlier versions of AHRQ software.
Compound 530143: Pyrimidine, 2,4,6-tris(trimethylsiloxy)-

Chemical compound data from PubChem database. IUPAC Name: [2,6-bis(trimethylsilyloxy)pyrimidin-4-yl]oxy-trimethylsilane. Molecular Formula: C13H28N2O3Si3. Molecular Weight: 344.63. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399530-T1: [Translated] COMPOSITION FOR DYING HUMAN KERATIN FIBERS WITH A 1H-PYRAZOLYL-ETHENYL-INDOLIUM DERIVATIVE

Composition for dyeing keratinic fibers comprises a pyrazolylvinylindolium derivative (I). Composition for dyeing keratinic fibers comprises a pyrazolylvinylindolium derivative of formula (I): [Image] R 11-4C alkyl or aryl(1-4C)alkyl; R 2H, 1-4C alkyl, 1-4C alkoxy, halo or NO 2; R 3-R 5H, 1-4C alkyl or optionally R-substituted aryl; R : halo, OH, 1-4C alkyl, 1-4C alkoxy, COOH or CF 3; X : an anion.
Connecticut: 2011-2012 NSDUH

This report presents Connecticut\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Patent AT-E400417-T1: [Translated] CALIBRATION MACHINE FOR LARGE NATURAL STONE SLABS SUCH AS GRANITE OR HARD STONE

The facing machine for large plates of natural stone, e.g. granite and hard stone slabs, comprises: a pair of rollers driven rotatively about a transverse axis to the slab direction of advance and mounted at a work surface grooving station; wherein the rollers consist of a plurality of cutting disks (1) having the same working diameter or being adjustable in height so as to compensate for minor variations in the roller diameters; wherein the cutting disks are fitted with diamond tool teeth (2) and aligned together in spaced apart relationship across the slab width so as to intermesh with the cutting disks of a leading/trailing one of the rollers; and wherein the slabs (20) are transported on a belt conveyor to a subsequent facing station where the ridges between grooves are removed; and has at least one of said rollers (3, 4) provided with an adjuster (14, 15) for setting its position relative to the other of said rollers and to a holding structure (9) along a transverse direction to the slab direction (A) of advance on said belt conveyor, for the purpose of allowing full (27) or partial (27 and 28) or no (28) interleave between grooves cut by said disks, according to the width of a slab being processed.
2019 Uniform Reporting System (URS) Table for Northern Mariana Islands

These are the 2019 Uniform Reporting System (URS) Output Tables for Northern Mariana Islands. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.
Patent AT-E400263-T1: [Translated] USE OF CARNITINE FOR PREPARATION OF A SOLUTION FOR INJECTION TO PREVENT OR AVOID ASCITES OF POULTRY BY IN-OVO INJECTION

Chemical patent from PubChem database. Patent Number: AT-E400263-T1. Title: Polymorphic Forms of Active Compounds. Filing Date: 1993-04-02. Inventors: Martinez, Carlos, Thompson, Emily. Abstract: The invention describes polymorphic forms of active pharmaceutical compounds, each characterized by distinct crystallographic and thermal properties. IPC Classifications: C07D, C07F, A61K. This patent covers 11 claims related to 2 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Compound 529018: 1,3-Dimethyl-2,5-diethylbenzene

Chemical compound data from PubChem database. IUPAC Name: 2,5-diethyl-1,3-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526463: Hexyl perfluorohexanoate

Chemical compound data from PubChem database. IUPAC Name: hexyl 2,2,3,3,4,4,5,5,6,6,6-undecafluorohexanoate. Molecular Formula: C12H13F11O2. Molecular Weight: 398.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529793: Ethyl 4-((E)-[4-(formylamino)phenyl]diazenyl)benzoate

Chemical compound data from PubChem database. IUPAC Name: propan-2-yl 2-[(2,2,2-trifluoroacetyl)amino]propanoate. Molecular Formula: C8H12F3NO3. Molecular Weight: 227.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.