AndreaBozzo/ceres-open-data-index huggingface dataset:
NSSP Emergency Department Visit Trajectories by State and Sub State Regions- COVID-19, Flu, RSV, Combined  

NSSP Emergency Department (ED) Visit Trajectories by State and Sub-State Regions- COVID-19, Flu, RSV, Combined. This dataset provides the percentage of emergency department patient visits for the specified pathogen of all ED patient visits for the specified geographic part of the country that were observed for the given week from data submitted to the National Syndromic Surveillance Program (NSSP). In addition, the trend over time is characterized as increasing, decreasing or no change, with exceptions for when there are no data available, the data are too sparse, or there are not enough data to compute a trend. These data are to provide awareness of how the weekly trend is changing for the given geographic region.  

Note that the reported sub-state trends are from Health Service Areas (HSA) and the data reported from the health care facilities located within the given HSA. Health Service Areas are regions of one or more counties that align to patterns of care seeking. The HSA level data are reported for each county in the HSA. 

More information on HSAs is available <a href="https://seer.cancer.gov/seerstat/variables/countyattribs/hsa.html"><b>here</b></a>.

For the emergency department time series, trajectory classifications reported on for sub-state (HSA) emergency department time series, trajectory classifications are based on approximations of the first derivative (slope) of trends that are smoothed using generalized additive models (GAMs). To determine time intervals in which the slope is sufficiently changing (i.e., rate of change distinguishable from 0), 95% confidence intervals for the slope approximations are calculated and assessed. Weeks with a 95% confidence interval not containing 0 are classified as increasing if the slope estimate is positive and decreasing if the slope estimate is negative. Weeks with a 95% confidence interval containing 0 are classified as stable. In the scenario that an HSA's time series is determined to be too sparse (i.e., many weeks with percentages of 0%), a model is not fit, and the HSA is classified as “sparse”.  

For additional information, please see: <a href="https://www.cdc.gov/ncird/surveillance/respiratory-illnesses/index.html#companion-guide"><b>Companion Guide: NSSP Emergency Department Data on Respiratory Illness</b></a>

Updated once per week on Fridays.
NNDSS - TABLE 1Q. Hepatitis B, perinatal infection to Hepatitis C, acute, Probable

NNDSS - TABLE 1Q. Hepatitis B, perinatal infection to Hepatitis C, acute, Probable - 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:

•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.

Footnotes:

*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
Compound 526506: Nickel(II) octaethylporphyrin

Chemical compound data from PubChem database. IUPAC Name: nickel(2+);2,3,7,8,12,13,17,18-octaethylporphyrin-22,24-diide. Molecular Formula: C36H44N4Ni. Molecular Weight: 591.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527278: Ortho,meta'-dinitro-diphenylmethane

Chemical compound data from PubChem database. IUPAC Name: 1-nitro-2-[(3-nitrophenyl)methyl]benzene. Molecular Formula: C13H10N2O4. Molecular Weight: 258.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Emergency airway management by intensive care unit nurses with the intubating laryngeal mask airway and the laryngeal tube

When using the laryngeal tube and the intubating laryngeal mask airway (ILMA), the medium-size (maximum volume 1100 ml) versus adult (maximum volume 1500 ml) self-inflating bags resulted in significantly lower lung tidal volumes. No gastric inflation occurred when using both devices with either ventilation bag. The newly developed medium-size self-inflating bag may be an option to further reduce the risk of gastric inflation while maintaining sufficient lung ventilation. Both the ILMA and laryngeal tube proved to be valid alternatives for emergency airway management in the experimental model used.
Kinetics of maternal immunity against rabies in fox cubs (

Background
          In previous experiments, it was demonstrated that maternal antibodies (maAb) against rabies in foxes (Vulpes vulpes) were transferred from the vixen to her offspring. However, data was lacking from cubs during the first three weeks post partum. Therefore, this complementary study was initiated.
        
        
          Methods
          Blood samples (n = 281) were collected from 64 cubs (3 to 43 days old) whelped by 19 rabies-immune captive-bred vixens. Sera was collected up to six times from each cub. The samples were analysed by a fluorescence focus inhibition technique (RFFIT), and antibody titres (nAb) were expressed in IU/ml. The obtained data was pooled with previous data sets. Subsequently, a total of 499 serum samples from 249 cubs whelped by 54 rabies-immune vixens were fitted to a non-linear regression model.
        
        
          Results
          The disappearance rate of maAb was independent of the vixens' nAb-titre. The maAb-titre of the cubs decreased exponentially with age and the half-life of the maAb was estimated to be 9.34 days. However, maAb of offspring whelped by vixens with high nAb-titres can be detected for longer by RFFIT than that of offspring whelped by vixens with relatively low nAb-titres. At a mean critical age of about 23 days post partum, maAb could no longer be distinguished from unspecific reactions in RFFIT depending on the amount of maAb transferred by the mother.
        
        
          Conclusions
          The amount of maAb cubs receive is directly proportional to the titre of the vixen and decreases exponentially with age below detectable levels in seroneutralisation tests at a relatively early age.
Acute-phase serum amyloid A production by rheumatoid arthritis
		  synovial tissue

Acute-phase serum amyloid A (A-SAA) is a major component of the
			 acute-phase response. A sustained acute-phase response in rheumatoid arthritis
			 (RA) is associated with increased joint damage. A-SAA mRNA expression was
			 confirmed in all samples obtained from patients with RA, but not in normal
			 synovium. A-SAA mRNA expression was also demonstrated in cultured RA
			 synoviocytes. A-SAA protein was identified in the supernatants of primary
			 synoviocyte cultures, and its expression colocalized with sites of macrophage
			 accumulation and with some vascular endothelial cells. It is concluded that
			 A-SAA is produced by inflamed RA synovial tissue. The known
			 association between the acute-phase response and progressive joint damage may
			 be the direct result of synovial A-SAA-induced effects on cartilage
			 degradation.
Compound 530513: 2-Chlorobenzoic acid, dodec-9-ynyl ester

Chemical compound data from PubChem database. IUPAC Name: dodec-9-ynyl 2-chlorobenzoate. Molecular Formula: C19H25ClO2. Molecular Weight: 320.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

Background
          The function of the fission yeast cullins Pcu1p and Pcu4p requires modification by the ubiquitin-related peptide Ned8p. A recent report by Lyapina et al. shows that the COP9/signalosome (CSN), a multifunctional eight subunit complex, regulates Ned8p modification of Pcu1p. Disruption of caa1/csn1, which encodes subunit 1 of the putative S. pombe CSN, results in accumulation of Pcu1p exclusively in the modified form. However, it remained unclear whether this reflects global control of all cullins by the entire CSN complex.
        
        
          Results
          We demonstrate that multiple CSN subunits control Ned8p modification of Pcu3p, another fission yeast cullin, which, in complex with the RING domain protein Pip1p, forms a ubiquitin ligase that functions in cellular stress response. Pcu3p is modified by Ned8p on Lys 729 and accumulates exclusively in the neddylated form in cells lacking the CSN subunits 1, 3, 4, and 5. These CSN subunits co-elute with Pcu3p in gel filtration fractions corresponding to ∼ 550 kDa and specifically bind both native and Ned8p-modified Pcu3p in vivo. While CSN does not influence the subcellular localization of Pcu3p, Pcu3p-associated in vitro ubiquitin ligase activity is stimulated in the absence of CSN.
        
        
          Conclusions
          Taken together, our data suggest that CSN is a global regulator of Ned8p modification of multiple cullins and potentially other proteins involved in cellular regulation.
Compound 525807: Cyclododecanol, HFB

Chemical compound data from PubChem database. IUPAC Name: cyclododecyl 2,2,3,3,4,4,4-heptafluorobutanoate. Molecular Formula: C16H23F7O2. Molecular Weight: 380.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525704: p-Methoxybenzylidene-decyl-amine

Chemical compound data from PubChem database. IUPAC Name: N-decyl-1-(4-methoxyphenyl)methanimine. Molecular Formula: C18H29NO. Molecular Weight: 275.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
TheArthritis Researchnon-peer-review depository

As readers may already be aware, the NIH have declared a plan that invites any journal that wishes to participate to deposit non-peer-reviewed research into PubMed Central, the new central repository for biomedical research data. To further the aim ofArthritis Researchto act as a focus for communication about all aspects of research into arthritis and related autoimmune diseases, a new non-peer-review depository will be launched in the journal in 2000. This new initiative will offer the community of arthritis researchers a valuable resource for depositing data which traditionally is not published in existing scientific journals. As editors, we believe that a facility for depositing non-peer-reviewed research data can bring major benefits for the dissemination of research findings, and we are enthusiastic about the availability of this new service.
Long term benzodiazepine use for insomnia in patients over the age of 60: discordance of patient and physician perceptions

Background
          The aim of this study was to determine and compare patients' and physicians' perceptions of benefits and risks of long term benzodiazepine use for insomnia in the elderly.
        
        
          Methods
          A cross-sectional study (written survey) was conducted in an academic primary care group practice in Toronto, Canada. The participants were 93 patients over 60 years of age using a benzodiazepine for insomnia and 25 physicians comprising sleep specialists, family physicians, and family medicine residents. The main outcome measure was perception of benefit and risk scores calculated from the mean of responses (on a Likert scale of 1 to 5) to various items on the survey.
        
        
          Results
          The mean perception of benefit score was significantly higher in patients than physicians (3.85 vs. 2.84, p < 0.001, 95% CI 0.69, 1.32). The mean perception of risk score was significantly lower in patients than physicians (2.21 vs. 3.63, p < 0.001, 95% CI 1.07, 1.77).
        
        
          Conclusions
          There is a significant discordance between older patients and their physicians regarding the perceptions of benefits and risks of using benzodiazepines for insomnia on a long term basis. The challenge is to openly discuss these perceptions in the context of the available evidence to make collaborative and informed decisions.
Patent AT-E401275-T1: [Translated] PIPE SWITCH

Pipe shunt (1) comprises a shunting arrangement (5) having a stopcock housing (6) which is larger than the stopcock (10). The stopcock moves between a conveying base position, in which the stopcock pivots between two conveying positions, and a cleaning position, in which the stopcock is spaced from the stopcock housing so that sealing elements (15, 18) sealing the stopcock against the stopcock housing in the conveying base position are ineffective. Preferred Features: The stop cock conically tapers in the direction of the conveying base position.
Patent AT-E401047-T1: [Translated] METHOD FOR PRODUCING A FLUTED EXTENDED LAMINATE AND USE OF SUCH LAMINATE IN AN ABSORBENT ARTICLE

A process for making a corrugated stretch laminate comprising the steps of providing a first carrier web having a first surface and a second surface; applying a first elastomeric composition in a fluid or molten state to the first surface of the carrier web to form at least one first elastic member; incrementally stretching in a first direction at least a portion of the carrier web to form a stretch composite preform; elongating the stretch composite preform in the first direction; joining a first substrate to the elongated stretch composite preform; and allowing the elongated stretch composite preform to recover to form said corrugated stretch laminate.
Compound 526323: 2,3,7-Tribromo-1,9-dichloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 2,3,7-tribromo-1,9-dichlorodibenzo-p-dioxin. Molecular Formula: C12H3Br3Cl2O2. Molecular Weight: 489.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2013 CMHS Uniform Reporting System (URS) Table for Texas

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Texas for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 525863: N,N-Dimethyl-2-phenyl-N'-heptyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N'-heptyl-N,N-dimethyl-2-phenylethanimidamide. Molecular Formula: C17H28N2. Molecular Weight: 260.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E399635-T1: [Translated] MEMBRANE FOR TURNING IN THE LOWER AREA

The section of the bead receiving seat (10a,10b) are formed in circular shape with the developed length (L1). The circumferential anchoring line of the turn up membrane (12a,12b) on the return segments (9a,9b) are axially offset towards the center of a drum by the length (L2) relative to the bead receiving seat. The other length is between 0.7 to 2 times the one length.
Patent AT-E401706-T1: [Translated] METHOD AND APPARATUS FOR PROCESSING A PHYSICAL CHANNEL CONTAINING PART OF A TRANSPORT FORMAT MESSAGE

Techniques for recovering data transmitted on a physical channel in which the channelization code is not known at the time of the data recovery. A modulated signal is received an processed to provide received samples. A hypothesized channelization code (e.g., an OVSF code in the W-CDMA system) is selected and used to process the received samples to generate partially processed symbols. The hypothesized channelization code is a "base" code that can be used to generate all possible channelization codes that may have been used for the physical channel. Intermediate results representative of the partially processed symbols are stored and, upon determination of the actual channelization code, further processed in accordance with the actual and hypothesized channelization codes to provide the final results.
Alabama (AL)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Alabama for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Cathepsin B cleavage of the trypsinogen activation peptide

Background
          Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the cathepsin B mediated activability of wildtype trypsinogen and their mutations N29I, N29T and R122H, which are associated to hereditary pancreatitis, revealed no differences. This action seems to be restricted to the K23-I24 peptide bond, which is the trypsinogen activation bond. Here we investigated the influence of the mutations D22G and K23R of the trypsinogen activation peptide on the cleavability by cathepsin B.
        
        
          Methods
          To investigate the functional impact of the TAP mutations on cathepsin B mediated cleavage of the trypsinogen activating K23-I24 bond, the corresponding peptides pWT, APFDDDDKIVGG; pD22G, APFDDDGKIVGG; and pK23R, APFDDDDRIVGG were digested with cathepsin B for 30 min at pH 3.8 and 5.0, and the fragments were analysed by high-performance liquid chromatography.
        
        
          Results
          Without cathepsin B, less than 1 % of the peptides were hydrolysed. After a 30-minute digestion with cathepsin B at pH 5, 96% of pWT, 48% of pK23R, but only 2.4% of pD22G were hydrolysed. At pH 3.8, the cathepsin B cleavage of pWT and pK23R was less than at pH 5, whereas the cleavage of pD22G was completely inhibited
        
        
          Conclusions
          Cathepsin B mediated trypsinogen activation seems not to be a crucial pathogenic step in hereditary pancreatitis patients with the trypsinogen mutations D22G and K23R.
Compound 528772: Pseudosarsasapogenin di-3,5-dinitrobenzoate

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32,34,34,36,36,38,38,40,40,42,42,44,44,46,46,48,48,50,50,52,52,54,54,56,56,58,58,60,60,62,62,64,64,66,66,68,68,70,70,72,72,74,74,76,76,78,78,80,80,82,82,84,84-tetraoctacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59,61,63,65,67,69,71,73,75,77,79,81,83-dotetracontaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70,72,74,76,78,80,82,84-dotetracontasilacyclotetraoctacontane. Molecular Formula: C84H252O42Si42. Molecular Weight: 3114.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hospital Cost Report Audited Data Print Image: 2010

This print image version of the Institutional Cost Report (ICR) has been audited by the DOH.  is the Institutional Cost Report (ICR) is a uniform report completed by New York hospitals to report income, expenses, assets, liabilities, and statistics to the Department of Health (DOH).  Under DOH regulations, (Part 86-1.2), Article 28 hospitals are required to file financial and statistical data with DOH annually.  The data filed is part of the ICR and is received electronically through a secured network.  This data is used to develop Medicaid rates, assist in the formulation of reimbursement methodologies, and analyze trends. For more information, check out:  http://www.health.ny.gov/facilities/hospital/index.htm.
Compound 527127: 2,3,8-Trichloro-dibenzothiophene

Chemical compound data from PubChem database. IUPAC Name: 2,3,8-trichlorodibenzothiophene. Molecular Formula: C12H5Cl3S. Molecular Weight: 287.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.