AndreaBozzo/ceres-open-data-index huggingface dataset:
In vivo and in vitro toxicity of a stainless-steel aerosol generated during thermal spray coating

Thermal spray coating is an industrial process where molten metal is sprayed onto a surface as a protective coat at high velocity. Using acellular, in vitro, and in vivo models, the toxicity of these aerosols was evaluated. An automated electric arc wire thermal spray coating aerosol generator and inhalation exposure system were developed to simulate an occupational exposure in an experimental model. Using the inhalation system, male Sprague-Dawley rats were exposed to stainless steel PMET720 aerosols at 25 mg/m3 x 4 hr/d x 9 d. Lung injury, inflammation, and cytokine alteration were determined. Resolution of the response was assessed by evaluating these parameters at 1, 7, 14 and 28 days after exposure. The aerosols generated were also collected and characterized. Macrophages were exposed to 0 – 200 µg/ml of the collected particles to determine cytotoxicity and screened for known mechanisms of toxicity. Other metal particles similar in composition and morphology, gas metal arc (GMA-SS) and manual metal arc (MMA-SS) stainless steel, were used as particle controls. The influence of pressure used during the process on the toxicity profile of the generated aerosols also was assessed and found to be minimal. The PMET720 thermal spray coating particles exhibited in vitro cytotoxicity and membrane damage only at the highest dose tested. Electron paramagnetic resonance spectroscopy (EPR) showed the PMET720 particles to have oxidative stress potential and caused a dose-dependent increase in intracellular oxidative stress. There also was a dose-dependent increase in NF-kB/AP-1 activity. Treatment with uptake inhibitors showed that the PMET720 particles were internalized via clathrin- and caveolar-mediated endocytosis as wells as actin-dependent pinocytosis/phagocytosis. In most of the cell assays, the two welding fume control particles generated a greater response compared to the PMET720 particles. In vivo, lung damage, inflammation and alteration in cytokines were observed 1 day after inhalation exposure, and this response returned to air control exposure levels by day 7. Alveolar macrophages retained the particulate even after 28 days after exposure. The results suggest that compared to stainless steel welding fumes, the PMET 720 aerosols were less potent, and the animals recovered from the acute pulmonary toxicity induced after 7 days.
Patent AT-E401210-T1: [Translated] WORKING MACHINE

A hybrid system working machine, during a normal working time, operated by a normal operation mode that the output of a power generator (13) and the accumulated power of a capacitor (13) are used while the engine (11) is operated over a high-efficiency range at a low output. Switching of a selector switch to a high-speed running mode position and running operation enable long-distance and high-speed running of an increase in engine output by a high-output operation mode.
Compound 528835: Glycerol, 2,3-dimethyl, 1-(12-methyltridecanoate)

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethoxypropyl 12-methyltridecanoate. Molecular Formula: C19H38O4. Molecular Weight: 330.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528387: 2,3,5-Trichloro-6-hydroxybenzaldehyde

Chemical compound data from PubChem database. IUPAC Name: 2,3,5-trichloro-6-hydroxybenzaldehyde. Molecular Formula: C7H3Cl3O2. Molecular Weight: 225.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The role of Serine Proteases and Serine Protease Inhibitors in the migration of Gonadotropin-Releasing Hormone neurons

Background
          Mechanisms regulating neuronal migration during development remain largely undefined. Extracellular matrix cues, target site released factors, and components of the migratory neurons themselves are likely all coordinated in time and space directing neurons to their appropriate locations. We have studied the effects of proteases and their inhibitors on the extracellular matrix and the consequences to the migration of gonadotropin releasing hormone (GnRH) neurons in the embryonic chick. Chick GnRH neurons differentiate in the olfactory epithelium, migrate along the olfactory nerve and enter the forebrain. The accessibility of this coherent cell group make it amenable for studying protease/inhibitor roles in migratory processes.
        
        
          Results
          Affigel blue beads were used to deliver a serine protease inhibitor, protease nexin-1 (PN-1), and a target protease, trypsin, to the olfactory epithelium coincident with initiation of GnRH neuronal migration. PN-1 inhibited neuronal migration while trypsin accelerated their transit into the CNS. Prior to initiation of migration, neither PN-1 nor trypsin altered the timing of neuronal exit. Trypsin did, however, accelerate the timing of neuronal crossing into the nerve-forebrain junction.
        
        
          Conclusions
          These data support the hypothesis that protease activity modulates neuronal movements across barriers. Moreover, the data suggest, for the first time, that aspects of GnRH neuronal migration may be cell autonomous but modulated by ECM alterations.
Behavioral Risk Factor Surveillance System (BRFSS) - Mental Health Indicators

<b>Data source description</b>: BRFSS measures health-related risk behaviors, chronic health conditions, and use of preventive services among U.S. adults through telephone interviews. BRFSS collects data in all 50 states as well as the District of Columbia and three U.S. territories of Guam, Puerto Rico, and U.S. Virgin Islands. Responses were used to produce estimates of experiences, behaviors, and conditions related to mental health and well-being for participating jurisdictions. Nationwide estimates are not available.  

 

<b>For additional information, please see</b>: <a href = "https://www.cdc.gov/mental-health/about-data/mental-health-data-sources.html" target ="_blank">Mental Health Data Sources</a>.
Patent AT-E401419-T1: [Translated] IMMOBILIZATION OF UNMODIFIED NUCLEIC ACIDS ON SUBSTRATES ACTIVATED WITH ACYL FLUORIDE

A method of attaching unmodified biopolymers, particularly, unmodified polynucleotides, directly to a solid support is provided. The method includes the steps of (a) providing unmodified biopolymers; (b) providing a solid support having at least one surface comprising pendant acyl fluoride functionalities, and (c) contacting the unmodified biopolymers with the solid support under a condition sufficient for allowing the attachment of the biopolymers to the solid support. The unmodified biopolymers may be nucleic acids, polypeptides, proteins, carbohydrates, lipids and analogues thereof. The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides. The DNA may be single or double stranded. A device including a solid support and unmodified biopolymers attached to the solid support by reaction with the pendant acyl fluoride functionalities of the solid support is also provided. The methods and devices of the present invention may be used in performing hybridization assays and immunoassays.
Patent AT-E399990-T1: [Translated] FAR FIELD LIGHT MICROSCOPIC METHOD AND DEVICE FOR DETERMINING AT LEAST ONE OBJECT SMALLER THAN THE WAVELENGTH USED

The present invention related to a far field light microscopical method for analysing at least one object having a subwavelength size in at least one spatial direction to obtain spatial information of the object, in particular size and topology thereof, comprising the steps of: n- labelling the object(s) with a plurality of suitable optical markers, each optical marker having a distinct spectral signature; n- providing illumination light to at least partially illuminate the object(s); n- subjecting the object(s) to the illumination light; n- detecting an optical response of the object(s); n- obtaining spatial information of the object(s),  nwherein the step of labelling the object comprises labelling a plurality of elements (E1, E2, E3...E N ) of the object, each element having a subwavelength size, such that each of the elements (E1, E2, E3...E N ) is randomly labelled nsuch that all elements (E1, E2, E3...E N ) in the plurality are labelled with different optical markers; or nsuch that at least two one pair of elements is labelled with the same optical marker and all pairs of elements labelled with the same optical marker in the plurality are labelled with different optical markers.
Compound 527996: Propanoic acid, 2,2-dichloro-, octyl ester

Chemical compound data from PubChem database. IUPAC Name: octyl 2,2-dichloropropanoate. Molecular Formula: C11H20Cl2O2. Molecular Weight: 255.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Incidence Tables (Prevalence Estimates) - 4.1 to 4.16

These detailed tables present totals and prevalence estimates of substance use initiation from the 2010 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens (including LSD, PCP, Ecstasy), inhalants, and the nonmedical use of prescription-type pain relievers (including OxyContin), tranquilizers, stimulants, sedatives, alcohol, and tobacco products (including cigarettes, smokeless tobacco, and cigars). Results are provided by age group and gender. Estimates are provided for both 2010 and 2009.
Loratadine and pseudoephedrine sulfate

Claritin-D 12 Hour is an over-the-counter extended-release tablet containing loratadine (5 mg) and pseudoephedrine sulfate (120 mg). It relieves allergy symptoms like runny nose, sneezing, and itchy throat, plus nasal congestion. Take orally as directed. Manufactured by Bayer HealthCare LLC. This information was generated using AI and is provided for informational and research purposes only.
Electronic Health Information Legal Epidemiology Data Set 2014

Authors: Cason Schmit, JD, Gregory Sunshine, JD, Dawn Pepin, JD, MPH, Tara Ramanathan, JD, MPH, Akshara Menon, JD, MPH, Matthew Penn, JD, MLIS
This legal data set consists of state statutes and regulations in effect as of January 1, 2014, related to electronic health information (EHI). Jurisdictions were limited to US states, territories, and the District of Columbia that had statutes and regulations in the Westlaw legal database that expressly referenced EHI. This data set includes 2,364 EHI-related laws representing 49 EHI uses in 54 jurisdictions. For information about research methods, please reference the Electronic Health Information Legal Epidemiology Protocol 2014.
Plan ID Crosswalk PUF - PY2016

The Plan ID Crosswalk PUF (CW-PUF) is one of the seven files that make up the Marketplace PUF. The purpose of the CW-PUF is to map QHPs and SADPs offered through the Marketplaces in 2014 to plans that will be offered through the Marketplaces in 2015. These data either originate from the Plan Crosswalk template (i.e., template field), an Excel-based form used by issuers to describe their plans in the QHP application process, or were generated by CCIIO for use in data processing (i.e., system-generated).This data dictionary describes the variables contained in the CW-PUF. Each record relates to a mapping between a plan offered in 2014 and a plan offered in 2015 at the county or county-zip code level.
Compound 530295: 1-[10,13-dimethyl-3,17-bis(trimethylsilyloxy)-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-N-methoxy-2-trimethylsilyloxyethanimine

Chemical compound data from PubChem database. IUPAC Name: 1-[10,13-dimethyl-3,17-bis(trimethylsilyloxy)-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-N-methoxy-2-trimethylsilyloxyethanimine. Molecular Formula: C31H61NO4Si3. Molecular Weight: 596.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Student Weight Status Category Reporting Results: 2010-2019

The Student Weight Status Category Reporting System (SWSCR) collects weight status category data (underweight, healthy weight, overweight or obese, based on BMI-for-age percentile).  The dataset includes separate estimates of the percent of students overweight, obese and overweight or obese for all reportable grades within the county and/or region and by grade groups (elementary and middle/high).
Patent AT-E401347-T1: [Translated] NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR

It is intended to provide a novel receptor of LPA and a method of screening a drug such as an LPA receptor antagonist using the same. Use as a lysophosphatidic acid (LPA) receptor comprising a G protein-coupled protein p2y9. More specifically, use of the G protein-coupled protein p2y9 as a lysophosphatidic acid (LPA) receptor. A method of screening an agonist or an antagonist to the LPA receptor as described above by using the receptor.
Compound 528024: 2-Phenylethyl pentafluorobenzoate

Chemical compound data from PubChem database. IUPAC Name: 2-phenylethyl 2,3,4,5,6-pentafluorobenzoate. Molecular Formula: C15H9F5O2. Molecular Weight: 316.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E39975-T1: [Translated] FITTING, PARTICULARLY FOR A PIECE OF FURNITURE.

A fitting for connecting two structural components. The fitting includes a locking device mounted on the first structural component and a support device mounted on the second structural component. A rotary member in the support device defines circumferentially extending conical surface against which the front end of the locking device is pressed when the two fitting devices are connected. The force exerted by the front end of the locking device causes the rotary member to be turned. The rotary member has a helical end face which is initially outside of the range of travel of the locking device. Upon turning of the rotary member, the helical end face comes into engagement with a countersurface of the locking device. The resulting connection can only be released by means of a tool. The structural components are pressed tightly together by a further turning of the rotary member. A piece of furniture composed of several structural components can be initially connected without the aid of a tool and can subsequently be tightened after the piece of furniture has been assembled. The fitting makes possible the connection of structural components where the tolerances in assembling the fitting devices are inaccurate or have been exceeded.
Compound 528864: 1-Methyl-2-(1-(propyldisulfanyl)propyl)disulfane

Chemical compound data from PubChem database. IUPAC Name: 1-(methyldisulfanyl)-1-(propyldisulfanyl)propane. Molecular Formula: C7H16S4. Molecular Weight: 228.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529868: 2-(Furan-2-ylmethyl)-3,5-dimethylpyrazine

Chemical compound data from PubChem database. IUPAC Name: 2-(furan-2-ylmethyl)-3,5-dimethylpyrazine. Molecular Formula: C11H12N2O. Molecular Weight: 188.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Tulsa, OK

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Tulsa, OK metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for the Tulsa metro area, Oklahoma, and the U.S. overall.
Behavioral Risk Factors – Vision and Eye Health Surveillance

2013-2022. This dataset is a de-identified summary table of vision and eye health data indicators from BRFSS, stratified by all available combinations of age group, race/ethnicity, gender, risk factor and state. BRFSS is a system of telephone surveys conducted by CDC that collect state data about U.S. residents regarding their health-related risk behaviors, chronic health conditions, and use of preventive services. BRFSS completes more than 400,000 adult interviews each year across 50 states, the District of Columbia, and three U.S. territories. BRFSS data for VEHSS includes one question from the core component related to Visual Function. Data were suppressed following NCHS standards. Data will be updated as it becomes available. Detailed information on VEHSS BRFSS analyses can be found on the VEHSS BRFSS webpage (link). General information about BRFSS can be found on the BRFSS website (https://www.cdc.gov/brfss). The VEHSS BRFSS dataset was last updated in November 2019.
Compound 530411: 5-Isopropylbicyclo(3.1.0)hex-2-ene-2-carbaldehyde

Chemical compound data from PubChem database. IUPAC Name: 5-propan-2-ylbicyclo[3.1.0]hex-2-ene-2-carbaldehyde. Molecular Formula: C10H14O. Molecular Weight: 150.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Fexofenadine hydrochloride oral

Fexofenadine Hydrochloride is an over-the-counter oral suspension used to relieve allergy symptoms like runny nose, itchy eyes, and sneezing. Each 5 mL contains 30 mg of the active ingredient, available in 120 mL or 240 mL bottles from Aurohealth LLC. It's a generic version of allergy medications, approved under ANDA213466. This information was generated using AI and is provided for informational and research purposes only.
ACF-OA-PI-13-01

This Program Instruction (PI) provides information for states and tribes who request FFP for costs associated with an automated data processing project covering one or more of the human services programs established by the Social Security Act. This addresses the use of commercial off-the-shelf (COTS) software applications by these agencies, including purchased, leased and hosted proprietary software products and software-as-a-service (SaaS) applications.

Metadata-only record linking to the original dataset. Open original dataset below.
Study of Fathers' Involvement in Permanency Placement Planning and Child Welfare Casework (2004-2005)

Most foster children are not living with their fathers at the time they are removed from their homes. While in foster care these children may experience even less contact with their nonresident fathers. This study examined child welfare practices with respect to identifying, locating, and involving fathers of children in foster care including whether child support resources were used. Local agency caseworkers were interviewed by phone about nearly 2,000 foster children in four study states. The study found that nonresident fathers are not often involved in case planning and nearly half were never contacted by the child welfare agency. The study was conducted in four states, Arizona, Massachusetts, Minnesota, and Tennessee, using three methods of data collection-interviews with child welfare administrators, case-level data collection through interviews with caseworkers, and data linkage between child welfare and child support systems. Of the three components, only the case-level data collected through interviews with caseworkers was contributed to the Archive.  Investigators interviewed local agency caseworkers about particular cases between October 2004 and February 2005 to examine front-line practices related to nonresident fathers. Cases were selected from among children who had been in foster care for at least 3 months but no more than 36 months. Children in the sample were all in foster care for the first time (first placement episode), and the child welfare agency's records indicated that each of the children's biological fathers were alive but not living in the home from which the child was removed. Additionally, only one child per mother was eligible for the study. Data on 1,958 eligible cases (83% response rate) were collected through telephone interviews with 1,222 caseworkers. The nonresident fathers of the children sampled represent a varied group. While most caseworkers, at the time of the interview, knew the identity of the fathers of children in the study's sample (88%), paternity had not yet been established for over one-third of the total sample's children (37%). A comparison with mothers found that demographic characteristics of identified nonresident fathers are similar to those of the resident mothers though fathers are slightly older (36 vs. 32 years old, on average) and more likely to have been married at some point. As expected, caseworkers appear to know less about nonresident fathers. The percent of "don't know" responses is much higher for nonresident fathers than for similar questions about resident mothers.

Investigators: Urban Institute- Karin Malm, Robert Geen, and Timothy Triplett
Compound 530180: Hippuric acid, 4-methoxy, TMS, # 2

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-[(4-methoxybenzoyl)amino]acetate. Molecular Formula: C13H19NO4Si. Molecular Weight: 281.38. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2015 CMHS Uniform Reporting System (URS) Table for Nebraska

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Nebraska.  The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Massachusetts (MA)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Massachusetts overall and for substate regions within Massachusetts. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Compound 527615: Hex-3-enyl 2-chloroacetate

Chemical compound data from PubChem database. IUPAC Name: hex-3-enyl 2-chloroacetate. Molecular Formula: C8H13ClO2. Molecular Weight: 176.64. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.