AndreaBozzo/ceres-open-data-index huggingface dataset:
NNDSS - Table II. Chlamydia to Coccidioidomycosis

NNDSS - Table II. Chlamydia to Coccidioidomycosis - 2015.In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed.The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories. Note:These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. Footnotes:C.N.M.I.: Commonwealth of Northern Mariana Islands. U: Unavailable.    -: No reported cases.    N: Not reportable.    NN: Not Nationally Notifiable.    NP: Nationally notifiable but not published.    Cum: Cumulative year-to-date counts.    Med: Median.    Max: Maximum. * Three low incidence conditions, rubella, rubella congenital, and tetanus, have been moved to Table 2 to facilitate case count verification with reporting jurisdictions. ��� Case counts for reporting year 2015 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for TB are displayed in Table IV, which appears quarterly.
Patent AT-E401320-T1: [Translated] DIPEPTIDYL PEPTIDASE INHIBITORS

Chemical patent from PubChem database. Patent Number: AT-E401320-T1. Title: Polymorphic Forms of Active Compounds. Filing Date: 2004-01-20. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: The invention describes polymorphic forms of active pharmaceutical compounds, each characterized by distinct crystallographic and thermal properties. IPC Classifications: A61K, A61L, A61F. This patent covers 18 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Five Leading Causes of Death by Age and Race/Ethnicity, New York State: Beginning 2018

This dataset contains the number of New York State deaths from five leading causes by jurisdiction, age group and race/ethnicity. For total across all age groups, top ten leading causes are displayed. The data presented here may differ from the Vital Statistics tables on the Department public website due to data updates. For more information, visit  https://www.health.ny.gov/statistics/vital_statistics/vs_reports_tables_list.htm,  where information from this dataset is presented in tabular form in Table 34.
Patent AT-E401585-T1: [Translated] FIBER OPTICAL MAIN DISTRIBUTOR AND CASSETTE

Chemical patent from PubChem database. Patent Number: AT-E401585-T1. Title: Polymorphic Forms of Active Compounds. Filing Date: 1999-04-06. Inventors: Patel, Amit, Jones, Michael. Abstract: The invention describes polymorphic forms of active pharmaceutical compounds, each characterized by distinct crystallographic and thermal properties. IPC Classifications: C07D, C07F, A61K. This patent covers 14 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Compound 527825: Aspartic acid, N-(trifluoroacetyl)-, dibutyl ester, L-

Chemical compound data from PubChem database. IUPAC Name: dibutyl 2-[(2,2,2-trifluoroacetyl)amino]butanedioate. Molecular Formula: C14H22F3NO5. Molecular Weight: 341.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules

Background
          Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the first 11–12 residues are highly conserved and the remainder of the repeat can vary in size Leucine-rich repeat proteins have been subdivided into seven subfamilies, none of which include members of the epidermal growth factor receptor or insulin receptor families despite the similarity between the 3D structure of the L domains of the type I insulin-like growth factor receptor and some leucine-rich repeat proteins.
        
        
          Results
          Here we have used profile searches and multiple sequence alignments to identify the repeat motif Ixx-LxIxx-Nx-Lxx-Lxx-Lxx-Lxx- in the L1 and L2 domains of the insulin receptor and epidermal growth factor receptors. These analyses were aided by reference to the known three dimensional structures of the insulin-like growth factor type I receptor L domains and two members of the leucine rich repeat family, porcine ribonuclease inhibitor and internalin 1B. Pectate lyase, another beta helix protein, can also be seen to contain the sequence motif and much of the structural features characteristic of leucine-rich repeat proteins, despite the existence of major insertions in some of its repeats.
        
        
          Conclusion
          Multiple sequence alignments and comparisons of the 3D structures has shown that right-handed beta helix proteins such as pectate lyase and the L domains of members of the insulin receptor and epidermal growth factor receptor families, are members of the leucine-rich repeat superfamily.
Compound 527998: (2E)-3-[4-(Methylsulfanyl)phenyl]-1-[4-(octadecyloxy)phenyl]-2-propen-1-one

Chemical compound data from PubChem database. IUPAC Name: 3-methylbutan-2-yl benzoate. Molecular Formula: C12H16O2. Molecular Weight: 192.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
QHP Landscape PY2025 Dental SHOP

The Dental SHOP Market file of the QHP Landscape Files contains information on certified dental plans offered through an Exchange to employers in the Small Business Health Options Program (SHOP) market. These plans are also known as Stand-alone Dental Plans (SADPs). The file reports plans offered by county for states in the Federally-facilitated Exchanges including states performing plan management functions, and State Based Exchanges using the federal platform for eligibility and enrollment.
Compound 525671: p-Bromobenzylidene-nonyl-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-nonylmethanimine. Molecular Formula: C16H24BrN. Molecular Weight: 310.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Biofilm formation by nontypeable

Background
          Nontypeable Haemophilus influenzae is an important cause of otitis media in children and lower respiratory tract infection in adults with chronic obstructive pulmonary disease (COPD). Several lines of evidence suggest that the bacterium grows as a biofilm in the human respiratory tract.
        
        
          Results
          Fifteen clinical isolates from middle ear fluid of children with otitis media and 15 isolates from sputum of adults with COPD were studied in an in vitro assay of biofilm formation. Striking variability among isolates was observed in their ability to form biofilms. Analysis of cell envelopes revealed minimal differences in banding patterns in polyacrylamide gels, alteration of expression of an epitope on lipooligosaccharide, and preservation of expression of selected epitopes on outer membrane proteins P2, P5 and P6 in biofilms compared to planktonically grown cells. A pilus-deficient variant showed a marked impairment in biofilm formation compared to its isogenic parent.
        
        
          Conclusions
          Nontypeable H. influenzae forms biofilms in vitro. Clinical isolates show substantial variability in their ability to grow as biofilms. Three major outer membrane proteins (P2, P5 and P6) are expressed during growth as a biofilm. Expression of lipooligosaccharide is altered during growth as a biofilm compared to planktonic growth. Pili are important in biofilm formation. As the role of biofilms in human infection becomes better defined, characterization of biofilms may be important in understanding the pathogenesis of infection and immune response to nontypeable H. influenzae in children with otitis media and adults with COPD.
Compound 527097: Fluoxetin (carbinol), diacetyl

Chemical compound data from PubChem database. IUPAC Name: [3-[acetyl(methyl)amino]-1-phenylpropyl] acetate. Molecular Formula: C14H19NO3. Molecular Weight: 249.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529050: 1,2,4-Trithiolane, 3-ethyl-5-(1-methylethyl), #1

Chemical compound data from PubChem database. IUPAC Name: 3-ethyl-5-propan-2-yl-1,2,4-trithiolane. Molecular Formula: C7H14S3. Molecular Weight: 194.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401705-T1: [Translated] ANTENNA DEVICES AND RADIO COMMUNICATIONS DEVICE USING THE SAME

A telecast-receiving antenna of a cellular phone having an improved gain is provided. A signal-band separating circuit 11 is interposed between a communication antenna 3 and a ground portion 2 that are disposed on a circuit board 1. The communication antenna 3 is connected to a communication circuit 12 by a signal line 14 via a signal-band separating circuit 11. A telecast-receiving antenna 10 is connected to a broadcast circuit 13 by a signal line 15. The signal-band separating circuit 11 transmits signals in a frequency band for communication between the communication antenna 3 and the communication circuit 12, and transmits signals in a frequency band for telecasts between the communication antenna 3 and the ground portion 2. The antenna length (electrical length) of the telecast-receiving antenna 10 is extended by adding the antenna length of the communication antenna 3 in addition to the antenna length of the ground portion 2, thereby improving the antenna gain during telecast reception.
A case of central nervous system vasculitis related to an episode of Guillain-Barrè syndrome

The authors report their knowledge about an uncommon case of isolated vasculitis, restricted to the left sylvian artery during an auto-immune Guillain-Barrè syndrome (GBS), sustained by cytomegalovirus (CMV). An acute cardiopulmonary failure requiring a ventilator and vasopressor support manifested, notwithstanding plasma exchanging and immune-modulating therapy. An IgM-enriched formula administration coincided with a rapid amelioration of GBS and vasculitis to a complete recovery the next month after her discharge to a rehabilitation centre.
Patent AT-E401393-T1: [Translated] RECOMBINANT PROTEINASE K

The invention concerns recombinant proteinase K. Furthermore a method for producing recombinant proteinase K is disclosed, which is characterized in that a) a host cell is transformed with a recombinant nucleic acid which codes for the zymogenic precursor of proteinase K, b) the host cell is cultured in such a manner that the zymogenic precursor of proteinase K is formed in the form of inclusion bodies in the host cell, c) the inclusion bodies are isolated and natured under conditions which result in the formation of the protease part of the zymogenic precursor in its natural conformation, d) the natured proteinase K is activated and purified.
Need for critical care in gynaecology: a population-based analysis

Introduction
          The purpose of this study was to note potential gynaecological risk factors leading to intensive care and to estimate the frequency, costs and outcome of management.
        
        
          Materials and methods
          In a cross-sectional study of intensive care admissions in Kuopio from March 1993 to December 2000, 23 consecutive gynaecological patients admitted to a mixed medical-surgical intensive care unit (ICU) were followed. We recorded demographics, admitting diagnoses, scores on the Acute Physiological and Chronic Health Evaluation (APACHE) II, clinical outcome and treatment costs.
        
        
          Results
          The overall need for intensive care was 2.3 per 1000 women undergoing major surgery during the study period. Patients were 55.4 ± 16.9 (mean ± SD) years old, with a mean APACHE II score of 14.07 (± 5.57). The most common diagnoses at admission were postoperative haemorrhage (43%), infection (39%) and cardiovascular disease (30%). The duration of stay in the ICU was 4.97 (± 9.28) (range 1–42) days and the mortality within 6 months was 26%, although the mortality in the ICU was 0%. The total cost of intensive care was approximately US$7044 per patient.
        
        
          Conclusions
          Very few gynaecological patients develop complications requiring intensive care. The presence of gynaecological malignancy and pre-existing medical disorders are clinically useful predictors of eventual outcome, but many cases occur in women with a low risk and this implies that the risk is relevant to all procedures. Further research is needed to determine effective preventive approaches.
Compound 527721: Pentyl 2,3-dichloropropanoate

Chemical compound data from PubChem database. IUPAC Name: pentyl 2,3-dichloropropanoate. Molecular Formula: C8H14Cl2O2. Molecular Weight: 213.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526627: 2-(2-{2-[2-(2-Diethylamino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-[2-(diethylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Molecular Formula: C14H31NO5. Molecular Weight: 293.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528299: Pyrazine, 2-decyl-3-ethoxy

Chemical compound data from PubChem database. IUPAC Name: 2-decyl-3-ethoxypyrazine. Molecular Formula: C16H28N2O. Molecular Weight: 264.41. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529219: 2,2,3,3,8,8,9,9-Octamethyl-4,7-dioxa-3,8-disiladecane

Chemical compound data from PubChem database. IUPAC Name: tert-butyl-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]-dimethylsilane. Molecular Formula: C14H34O2Si2. Molecular Weight: 290.59. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401001-T1: [Translated] PLANTS TO CONTROL DAMAGE CAUSED BY FEEDERING INSECTS

Plants are disclosed which are capable of expressing, in a tissue or tissues susceptible to damage by feeding insects, an exogenous protein(s) such as fusolin or a fusolin-like protein, to reduce damage to the plant by inhibiting feeding, growth and/or development of insects. Feed baits comprising spindle bodies, spindle-like bodies or constituent protein(s) thereof which inhibit feeding, growth and/or development of insects are also disclosed.
A database for the provisional identification of species using only genotypes: web-based genome profiling

Background
          For a long time one could not imagine being able to identify species on the basis of genotype only as there were no technological means to do so. But conventional phenotype-based identification requires much effort and a high level of skill, making it almost impossible to analyze a huge number of organisms, as, for example, in microbe-related biological disciplines. Comparative analysis of 16S rRNA has been changing the situation, however. We report here an approach that will allow rapid and accurate phylogenetic comparison of any unknown strain to all known type strains, enabling tentative assignments of strains to species. The approach is based on two main technologies: genome profiling and Internet-based databases.
        
        
          Results
          A complete procedure for provisional identification of species using only their genomes is presented, using random polymerase chain reaction, temperature-gradient gel electrophoresis, image processing to generate 'species-identification dots' (spiddos) and data processing. A database website for this purpose was also constructed and operated successfully. The protocol was standardized to make the system reproducible and reliable. The overall methodology thus established has remarkable aspects in that it enables non-experts to obtain an initial species identification without a lot of effort and is self-developing; that is, species can be determined more definitively as the database is used more and accumulates more genome profiles.
        
        
          Conclusions
          We have devised a methodology that enables provisional identification of species on the basis of their genotypes only. It is most useful for microbe-related disciplines as they face the most serious difficulties in species identification.
The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia

Background
          Manipulation of total homocysteine concentration with oral methionine is associated with impairment of endothelial-dependent vasodilation. This may be caused by increased oxidative stress. Vitamin C is an aqueous phase antioxidant vitamin and free radical scavenger. We hypothesised that if the impairment of endothelial function related to experimental hyperhomocysteinaemia was free radically mediated then co-administration of vitamin C should prevent this.
        
        
          Methods
          Ten healthy adults took part in this crossover study. Endothelial function was determined by measuring forearm blood flow (FBF) in response to intra-arterial infusion of acetylcholine (endothelial-dependent) and sodium nitroprusside (endothelial-independent). Subjects received methionine (100 mg/Kg) plus placebo tablets, methionine plus vitamin C (2 g orally) or placebo drink plus placebo tablets. Study drugs were administered at 9 am on each study date, a minimum of two weeks passed between each study. Homocysteine (tHcy) concentration was determined at baseline and after 4 hours. Endothelial function was determined at 4 hours. Responses to the vasoactive substances are expressed as the area under the curve of change in FBF from baseline. Data are mean plus 95% Confidence Intervals.
        
        
          Results
          Following oral methionine tHcy concentration increased significantly versus placebo. At this time endothelial-dependent responses were significantly reduced compared to placebo (31.2 units [22.1-40.3] vs. 46.4 units [42.0-50.8], p < 0.05 vs. Placebo). Endothelial-independent responses were unchanged. Co-administration of vitamin C did not alter the increase in homocysteine or prevent the impairment of endothelial-dependent responses (31.4 [19.5-43.3] vs. 46.4 units [42.0-50.8], p < 0.05 vs. Placebo)
        
        
          Conclusions
          This study demonstrates that methionine increased tHcy with impairment of the endothelial-dependent vasomotor responses. Administration of vitamin C did not prevent this impairment and our results do not support the hypothesis that the endothelial impairment is mediated by adverse oxidative stress.
Compound 525463: 3-Thia-5-hexene-1-thiol

Chemical compound data from PubChem database. IUPAC Name: 2-prop-2-enylsulfanylethanethiol. Molecular Formula: C5H10S2. Molecular Weight: 134.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525718: N-(4-Methylbenzylidene)-4-chloroaniline

Chemical compound data from PubChem database. IUPAC Name: N-(4-chlorophenyl)-1-(4-methylphenyl)methanimine. Molecular Formula: C14H12ClN. Molecular Weight: 229.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Standardized Precipitation Index, 1895-2016

This dataset provides data at the county level for the contiguous United States. It includes monthly Standardized Precipitation Index (SPI) data from 1895-2016 provided by the Cooperative Institute for Climate and Satellites - North Carolina. Please refer to the metadata attachment for more information.

Learn more about drought on the Tracking Network's website: https://ephtracking.cdc.gov/showDroughtLanding.

By using these data, you signify your agreement to comply with the following requirements: 
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2.	Do not attempt to learn the identity of any person included in the data and do not combine these data with other data for the purpose of matching records to identify individuals. 
3.	Do not disclose of or make use of the identity of any person or establishment discovered inadvertently and report the discovery to: trackingsupport@cdc.gov. 
4.	Do not imply or state, either in written or oral form, that interpretations based on the data are those of the original data sources and CDC unless the data user and data source are formally collaborating. 
5.	Acknowledge, in all reports or presentations based on these data, the original source of the data and CDC. 
6.	Suggested citation: Centers for Disease Control and Prevention. National Environmental Public Health Tracking Network. Web. Accessed: insert date. www.cdc.gov/ephtracking. 

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