AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E400686-T1: [Translated] DEVICE FOR FORMING HANGING LOOP IN MACHINE FOR TREATING TEXTILE SURFACE STRUCTURES

A device for forming fabric folds in a machine for treating fabrics, particularly a folded fabric steaming machine, comprising a fabric treatment chamber (1), equipped with an inlet (6) and an outlet (7) of the fabric and a chain conveyor (T) for advancing the fabric in said chamber (1). The conveyor comprises rods (20), whereon folds are formed and supported, which are mounted on the conveyor by means of arms (24). The device provides two shaped plates (30) whereon the arms (24) supporting the rods (20) slide. When the fabric advances, the arms (24) are overturned by lifting the rods (20), from a condition hung to the transport chains in the ascending tract (18) thereof, to a condition resting on rails (28) arranged above the active branches (16) of said chains.
Supporting Evidence-Based Home Visitation Programs to Prevent Child Abuse and Neglect Project: Utah Department of Health

Location:

Salt Lake City, Utah

Home Visiting Program Selected:

Nurse Family Partnership, and Healthy Families America

Home Visiting Target Population:

First-time mothers who are 185% below the federal poverty level, and eligible for Medicaid or the Woman, Infants and Children (WIC) program

Project Overview:
Four of Utah's counties—all of them in populous areas of the state—have home visiting programs, established in 2007. The fifth populous county, and all the remaining counties, which are located in non-urban areas and have some of the state's highest child poverty and maltreatment rates, lack home visiting programs. With their grant funding, the Utah Department of Health plans to establish an Office of Home Visiting (OHV) to work with the Division of Child and Family Services in the state's Department of Human Services, and with the Division's Child Abuse Prevention Specialist, to support existing programs and to spread the use of evidence-based models of home visiting throughout the state. OHV plans to develop or improve linkages between home visiting programs and other service systems such as health care, substance abuse treatment, and mental health providers, and to identify new sources of funding for home visiting programs. OHV will seek to leverage potential funding for these new programs through possible sources such as Medicaid, Temporary Assistance to Needy Families, and the Maternal and Child Health Block Grant. They then hope to establish additional evidence-based programs in the state. The evaluation coordinator will work with an external evaluator from the Intervention Research Institute at Utah State University. The grantee currently plans to compare data from local home visiting programs to national data.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 529954: 3-[2-Methyl-(3-thienyldithio)pentan-2-one

Chemical compound data from PubChem database. IUPAC Name: 3-[(2-methylthiophen-3-yl)disulfanyl]pentan-2-one. Molecular Formula: C10H14OS3. Molecular Weight: 246.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526157: Dibutyl 3-methyl-phenyl phosphate

Chemical compound data from PubChem database. IUPAC Name: dibutyl (3-methylphenyl) phosphate. Molecular Formula: C15H25O4P. Molecular Weight: 300.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530426: Isoledene

Chemical compound data from PubChem database. IUPAC Name: 1,1,4,7-tetramethyl-1a,2,3,4,5,6,7,7b-octahydrocyclopropa[e]azulene. Molecular Formula: C15H24. Molecular Weight: 204.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E39966-T1: [Translated] DEVICE FOR REINFORCEMENT OF THE REAR WALL OF AN ARMORED COMPARTMENT, ESPECIALLY IN ARMORED COMPARTMENTS.

1. Reinforcement cassette device for bank safe compartments including a rear wall, side walls and horizontal pannels fixed to the walls and defining at their anterior portion U-shaped reinforcement profiles, said compartments being closed by pivoting doors, characterized in that the rear wall or bottom (7) of the cassette or compartment includes an extra wall having in its center a shaft (5) resting outside and supporting a cam (6), the rotation of which allows pushing back the heads (7) of at least two rods (8) guided by sliding keepers (9) rigidly connected to the outer face of bottom (2), these rods (8) forming at their end (8a) bolts penetrating inside catches provided in the safe cassettes on in the safe.
Compound 530547: 3-Cyclopentylpropionic acid, tetradecyl ester

Chemical compound data from PubChem database. IUPAC Name: tetradecyl 3-cyclopentylpropanoate. Molecular Formula: C22H42O2. Molecular Weight: 338.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Upregulation of the SERCA-type Ca

Background
          Ca2+-ATPases of endoplasmic reticulum (SERCAs) are responsible for maintenance of the micro- to millimolar Ca2+ ion concentrations within the endoplasmic reticulum (ER) of eukaryotic cells. This intralumenal Ca2+ storage is important for the generation of Ca2+ signals as well as for the correct folding and posttranslational processing of proteins entering ER after synthesis. ER perturbations such as depletion of Ca2+ or abolishing the oxidative potential, inhibition of glycosylation, or block of secretory pathway, activate the Unfolded Protein Response, consisting of an upregulation of a number of ER-resident chaperones/stress proteins in an effort to boost the impaired folding capacity.
        
        
          Results
          We show here that in PC12 cells, depletion of ER Ca2+ by EGTA, as well as inhibition of disulphide bridge formation within the ER by dithiotreitol or inhibition of N-glycosylation by tunicamycin, led to a 2- to 3-fold increase of the SERCA-mediated 45Ca2+ transport to microsomes isolated from cells exposed to these stress agents. The time course of this response corresponded to that for transcriptional upregulation of ER stress proteins, as well as to the increase in the SERCA2b mRNA, as we recently observed in an independent study.
        
        
          Conclusions
          These findings provide the first functional evidence for the increase of SERCA pumping capacity in cells subjected to the ER stress. Since at least three different and unrelated mechanisms of eliciting the ER stress response were found to cause this functional upregulation of Ca2+ transport into the ER, these results support the existence of a coupling between the induction of the UPR pathway in general, and the regulation of expression of at least one of the SERCA pump isoforms.
Octreotide acetate

Octreotide Acetate is a generic prescription injectable medication, available in strengths of 200 mcg/mL and 1 mg/mL, used for intravenous or subcutaneous administration. It acts as a somatostatin analog to help manage certain hormonal conditions. Manufactured by Hikma Pharmaceuticals USA Inc. under ANDA076330. This information was generated using AI and is provided for informational and research purposes only.
Compound 525417: 2-Methyl-4-thianonane

Chemical compound data from PubChem database. IUPAC Name: 1-(2-methylpropylsulfanyl)pentane. Molecular Formula: C9H20S. Molecular Weight: 160.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Pennsylvania (PA)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Pennsylvania overall and for substate regions within Pennsylvania. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Table 14. Tobacco Product Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past month tobacco use by those aged 12 or older by State and substate regions.
Epithelial antimicrobial peptides in host defense against infection

One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid motifs. Peptides of the defensin, cathelicidin, and histatin classes are found in humans. In the airways, α-defensins and the cathelicidin LL-37/hCAP-18 originate from neutrophils. β-Defensins and LL-37/hCAP-18 are produced by the respiratory epithelium and the alveolar macrophage and secreted into the airway surface fluid. Beside their direct antimicrobial function, antimicrobial peptides have multiple roles as mediators of inflammation with effects on epithelial and inflammatory cells, influencing such diverse processes as proliferation, immune induction, wound healing, cytokine release, chemotaxis, protease-antiprotease balance, and redox homeostasis. Further, antimicrobial peptides qualify as prototypes of innovative drugs that might be used as antibiotics, anti-lipopolysaccharide drugs, or modifiers of inflammation.
Clonidine hydrochloride

Clonidine Hydrochloride is a generic prescription medication available as oral tablets in strengths of 0.1 mg, 0.2 mg, and 0.3 mg. It works as an adrenergic alpha2-agonist and central alpha-2 adrenergic agonist, often used to treat high blood pressure and other conditions. Manufactured by Solco Healthcare LLC and sponsored by PRINSTON INC under ANDA 077901. This information was generated using AI and is provided for informational and research purposes only.
Compound 526636: (3,4-Dimethoxyoxolan-2-yl)methyl acetate

Chemical compound data from PubChem database. IUPAC Name: (3,4-dimethoxyoxolan-2-yl)methyl acetate. Molecular Formula: C9H16O5. Molecular Weight: 204.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529060: 3-Isopropyl-2,4,5-trithiahexane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-1-(methyldisulfanyl)-1-methylsulfanylpropane. Molecular Formula: C6H14S3. Molecular Weight: 182.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529321: Oxetane, 3-methyl-3-(1-methylethyl)

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-3-propan-2-yloxetane. Molecular Formula: C7H14O. Molecular Weight: 114.19. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Phenylephrine hydrochloride

Phenylephrine Hydrochloride is a prescription eye drop (ophthalmic solution) that works as an alpha-1 adrenergic agonist to constrict blood vessels and dilate the pupil, often used for eye exams or certain eye conditions. It's available as a 10% (100 mg/mL) strength in a 5 mL dropper bottle, manufactured by Lifestar Pharma LLC under FDA application ANDA216496. This information was generated using AI and is provided for informational and research purposes only.
Patent AT-E400009-T1: [Translated] SYSTEM FOR CONTROLLING THE ACCESS OF CONTROL PROGRAMS TO SYSTEM RESOURCES

The present invention is a system for controlling exclusive access by control programs (30) to system resources (52). A system in accordance with the invention includes a plurality of addressable locations (12, 14, 16, 18, 20 and 22) in the system; a communication system (24) connecting the addressable locations which transmits communications between the addressable locations; a plurality of machines (26), the machines being located at at least one of the addressable locations; a plurality of control programs which use resources including a plurality of machine control programs, each machine control program controlling at least one machine; and a plurality of resource managers (32), the resource managers being located at a plurality of the addressable locations, each resource manager communicating over the communication system with at least one other resource manager, and the plurality of resource managers arbitrating which control program of the plurality of control programs is given exclusive use of at least one resource during execution of the control program.
The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution

Background
          Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human tumor cell lines (HCT-116, MiAPaCa-2 and A-549) bearing a point mutation in the K-Ras gene.
        
        
          Results
          RPR-130401 inhibited cell growth with an IC50 of 50 nM (HCT-116), 120 nM (MiAPaCa-2) and 710 nM (A-549), with a poor incidence of apoptosis. The drug brought about G1 and S phase depletion together with arrest of cells in G2 phase and induced a significant accumulation of hyperploid cells showing active S phase DNA synthesis, with HCT-116 and A-549 cells being the most and least responsive, respectively. The drug also produced dramatic changes of the nuclear lamin B pattern, without lamin B cleavage and perturbation of the actin cytoskeleton. On the other hand, RPR-130401 elicited strictly additive interaction in combined treatment with ionizing radiation with regard to cell kill, altered cell cycle progression and induced hyperploidy.
        
        
          Conclusions
          The data suggest that disruption of orderly progression through mitosis and cytokinesis, is a major outcome of drug action and that this effect proceeds from inhibition of lamin B farnesylation. It is anticipated from the strict additivity of RPR-130401 and radiation that neither induced radiation resistance nor acute or late complications of radiotherapy, should occur in combined treatment with RPR-130401.
Special Treatment Facilities

<div>[<a href='https://files.hawaii.gov/dbedt/op/gis/data/Special_Treatment_Facilities.pdf' target='_blank' rel='nofollow ugc noopener noreferrer'>Metadata</a>]  Locations of special treatment facilities in the State of Hawaii as of November 2021. Source: Created by Hawaii Statewide GIS Program from data downloaded from Hawaii State Department of Health Office of Health Care Assurance (OHCA). <br /></div><div><br /></div><div>For more information, please see metadata at <a href='https://files.hawaii.gov/dbedt/op/gis/data/Special_Treatment_Facilities.pdf' target='_blank' rel='nofollow ugc noopener noreferrer'>https://files.hawaii.gov/dbedt/op/gis/data/Special_Treatment_Facilities.pdf</a> or contact Hawaii Statewide GIS Program, Office of Planning and Sustainable Development, State of Hawaii; PO Box 2359, Honolulu, Hi. 96804; (808) 587-2846; email: <a href='mailto:gis@hawaii.gov' target='_blank' rel='nofollow ugc noopener noreferrer'>gis@hawaii.gov</a>; Website: <a href='https://planning.hawaii.gov/gis' target='_blank' rel='nofollow ugc noopener noreferrer'>https://planning.hawaii.gov/gis</a>. Source: State of Hawaii Dept. of Health, November 2021.</div>
Compound 528866: 4,5,7,8-Tetrathiadecane, 6-ethyl

Chemical compound data from PubChem database. IUPAC Name: 1-(ethyldisulfanyl)-1-(propyldisulfanyl)propane. Molecular Formula: C8H18S4. Molecular Weight: 242.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Dorzolamide hydrochloride and timolol maleate preservative free

Dorzolamide Hydrochloride and Timolol Maleate is a preservative-free ophthalmic solution (eye drops) used to lower intraocular pressure in patients with glaucoma or ocular hypertension. It combines dorzolamide, a carbonic anhydrase inhibitor, and timolol, a beta-blocker, to reduce fluid production in the eye. Manufactured by Micro Labs Limited, it's available as a prescription drug in single-use vials. This information was generated using AI and is provided for informational and research purposes only.
Compound 526333: 2,4,8-Tribromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,4,8-tribromodibenzofuran. Molecular Formula: C12H5Br3O. Molecular Weight: 404.88. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526730: Triethylene glycol, nonyl ether, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-[2-(2-nonoxyethoxy)ethoxy]ethoxy]silane. Molecular Formula: C18H40O4Si. Molecular Weight: 348.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526239: 1,2,4,6,8-Pentabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,4,6,8-pentabromodibenzofuran. Molecular Formula: C12H3Br5O. Molecular Weight: 562.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530100: 2-(3-methoxy-4-trimethylsilyloxyphenyl)-N-trimethylsilylethanamine

Chemical compound data from PubChem database. IUPAC Name: 2-(3-methoxy-4-trimethylsilyloxyphenyl)-N-trimethylsilylethanamine. Molecular Formula: C15H29NO2Si2. Molecular Weight: 311.57. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401735-T1: [Translated] KEYBOARD AND MICROPHONE ARRANGEMENT

Disclosed is a keypad and microphone arrangement for a communication device. The arrangement comprises: a microphone; a printed circuit board for mounting the microphone thereon; and a support mounted to the PCB around the microphone to support a keypad and to at least partially cover the microphone, the support having a first opening from its top surface, through its interior to its bottom surface. The arrangement may be used in any communication device having voice reception capabilities.
Program Instruction (PI-20-12)

This Program Instruction sets forth the eligibility requirements and grant application procedures for the basic, data and training CIP grants for FY 2022, including the development of a new five-year strategic plan, and to provide guidance on the requirements for state courts to continuously assess and improve the handling of court proceedings related to child welfare and enhance collaboration with title IV-B/IV-E agencies and tribes.

Metadata-only record linking to the original dataset. Open original dataset below.
Arterial Wall Properties and Womersley Flow in Fabry Disease

Background
          Fabry disease is an X-linked recessive lysosomal storage disease resulting in the cellular accumulation of globotriaosylceramide particularly globotriaosylceramide. The disease is characterized by a dilated vasculopathy with arterial ectasia in muscular arteries and arterioles. Previous venous plethysomographic studies suggest enhanced endothelium-dependent vasodilation in Fabry disease indicating a functional abnormality of resistance vessels.
        
        
          Methods
          We examined the mechanical properties of the radial artery in Fabry disease, a typical fibro-muscular artery. Eight control subjects and seven patients with Fabry disease had a right brachial arterial line placed allowing real time recording of intra-arterial blood pressure. Real time B-mode ultrasound recordings of the right radial artery were obtained simultaneously allowing calculation of the vessel wall internal and external diameter, the incremental Young's modulus and arterial wall thickness. By simultaneously measurement of the distal index finger-pulse oximetry the pulse wave speed was calculated. From the wave speed and the internal radial artery diameter the volume flow was calculated by Womersley analysis following truncation of the late diastolic phase.
        
        
          Results
          No significant difference was found between Fabry patients and controls for internal or external arterial diameters, the incremental Young's modulus, the arterial wall thickness, the pulse wave speed and the basal radial artery blood flow. Further, no significant difference was found for the radial artery blood flow in response to intra-arterial acetylcholine or sodium nitroprusside. Both drugs however, elevated the mean arterial flow.
        
        
          Conclusions
          The current study suggests that no structural or mechanical abnormality exists in the vessel wall of fibro-muscular arteries in Fabry disease. This may indicate that a functional abnormality downstream to the conductance vessels is the dominant feature in development Fabry vasculopathy.
Compound 525429: 2-Methyl-2-(methylsulfanyl)butane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-methylsulfanylbutane. Molecular Formula: C6H14S. Molecular Weight: 118.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525661: p-Bromobenzylidene-(4-ethoxyphenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-(4-ethoxyphenyl)methanimine. Molecular Formula: C15H14BrNO. Molecular Weight: 304.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.