AndreaBozzo/ceres-open-data-index huggingface dataset:
Systematic reviews of complementary therapies - an annotated bibliography. Part 1: Acupuncture

Background
          Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three major complementary therapies (acupuncture, herbal medicine, homeopathy). This article is dealing with acupuncture. Potentially relevant reviews were searched through the register of the Cochrane Complementary Medicine Field, the Cochrane Library, Medline, and bibliographies of articles and books. To be included articles had to review prospective clinical trials of acupuncture; had to describe review methods explicitly; had to be published; and had to focus on treatment effects. Information on conditions, interventions, methods, results and conclusions was extracted using a pretested form and summarized descriptively.
        
        
          Results
          From a total of 48 potentially relevant reviews preselected in a screeening process 39 met the inclusion criteria. 22 were on various pain syndromes or rheumatic diseases. Other topics addressed by more than one review were addiction, nausea, asthma and tinnitus. Almost unanimously the reviews state that acupuncture trials include too few patients. Often included trials are heterogeneous regarding patients, interventions and outcome measures, are considered to have insufficient quality and contradictory results. Convincing evidence is available only for postoperative nausea, for which acupuncture appears to be of benefit, and smoking cessation, where acupuncture is no more effective than sham acupuncture.
        
        
          Conclusions
          A large number of systematic reviews on acupuncture exists. What is most obvious from these reviews is the need for (the funding of) well-designed, larger clinical trials.
Compound 525498: 5-Tert-butyl-2-ethylthiofuran

Chemical compound data from PubChem database. IUPAC Name: 2-tert-butyl-5-ethylsulfanylfuran. Molecular Formula: C10H16OS. Molecular Weight: 184.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530290: 1-Hexene, 2,4,6-tris-trimethylsilyl

Chemical compound data from PubChem database. IUPAC Name: 1,5-bis(trimethylsilyl)hex-5-en-3-yl-trimethylsilane. Molecular Formula: C15H36Si3. Molecular Weight: 300.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526466: Propyl perfluorohexanoate

Chemical compound data from PubChem database. IUPAC Name: propyl 2,2,3,3,4,4,5,5,6,6,6-undecafluorohexanoate. Molecular Formula: C9H7F11O2. Molecular Weight: 356.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529151: 1-Heptanamine, bis-TMS

Chemical compound data from PubChem database. IUPAC Name: N,N-bis(trimethylsilyl)heptan-1-amine. Molecular Formula: C13H33NSi2. Molecular Weight: 259.58. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2015 CMHS Uniform Reporting System (URS) Table for District of Columbia

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for District of Columbia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Miami - Dade Div: Drug-Related Emergency Department Visits, 2004-2011 - Underage Drinking

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving underage drinking in Dade division of the Miami metropolitan area, covering 2004-2011.  Underage drinking includes ED visits that involve alcohol use (alone or with other drugs) for patients under the age of 21.
2021-2023 Companion Report on Race/Ethnicity

Review this high-level visual representation of key outcomes by race and ethnicity from the combined 2021-2023 National Surveys on Drug Use and Health (NSDUH). This infographic, accompanying the2023 NSDUH National Report, covers substance use, substance use disorders, mental health issues, suicidality, and perceived recovery from substance use problems or mental health issues among the noninstitutionalized population aged 12 or older in the United States.
California Presentation on Strategies for Reducing Long-Term Foster Care Population

The state of California has two Permanency Innovation Initiative (PII) grantees; they operate the California Partners for Permanency (CAPP)  and Recognize. Intervene. Support. Empower (RISE) projects. These presentation provides an overview of their strategies to reduce the number of children and youth in long-term foster care.

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Compound 527977: 4-Cyclohexene-1,2-dicarboxylic acid, 4-chloro, dimethyl ester

Chemical compound data from PubChem database. IUPAC Name: dimethyl 4-chlorocyclohex-4-ene-1,2-dicarboxylate. Molecular Formula: C10H13ClO4. Molecular Weight: 232.66. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528780: Cyclohexadecasiloxane, dotriacontamethyl-

Chemical compound data from PubChem database. IUPAC Name: 2,2,4,4,6,6,8,8,10,10,12,12,14,14,16,16,18,18,20,20,22,22,24,24,26,26,28,28,30,30,32,32-dotriacontamethyl-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31-hexadecaoxa-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32-hexadecasilacyclodotriacontane. Molecular Formula: C32H96O16Si16. Molecular Weight: 1186.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants

Background
          Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with major economical impact and complex genomes. In this paper we exploit the recently described CODEHOP primer design and PCR strategy for targeted isolation of homologues in large gene families.
        
        
          Results
          The method was tested with two different objectives. The first was to analyze the evolution of the CYP98 family of cytochrome P450 genes involved in 3-hydroxylation of phenolic compounds and lignification in a broad range of plant species. The second was to isolate an orthologue of the sorghum glucosyl transferase UGT85B1 and to determine the complexity of the UGT85 family in wheat. P450s of the CYP98 family or closely related sequences were found in all vascular plants. No related sequence was found in moss. Neither extensive duplication of the CYP98 genes nor an orthologue of UGT85B1 were found in wheat. The UGT85A subfamily was however found to be highly variable in wheat.
        
        
          Conclusions
          Our data are in agreement with the implication of CYP98s in lignification and the evolution of 3-hydroxylation of lignin precursors with vascular plants. High conservation of the CYP98 family strongly argues in favour of an essential function in plant development. Conversely, high duplication and diversification of the UGT85A gene family in wheat suggests its involvement in adaptative response and provides a valuable pool of genes for biotechnological applications. This work demonstrates the high potential of the CODEHOP strategy for the exploration of large gene families in plants.
Compound 527848: 2,4-Dichlorobenzyl octyl ether

Chemical compound data from PubChem database. IUPAC Name: 2,4-dichloro-1-(octoxymethyl)benzene. Molecular Formula: C15H22Cl2O. Molecular Weight: 289.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery

Background
          Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these species may be implicated in certain pathophysiological events. We studied the possible role of low molecular mass dinitrosyl iron complexes in the control of noradrenaline release in electrically stimulated rat tail artery.
        
        
          Results
          A model complex, dinitrosyl-iron-thiosulfate (at 1–10 μM) produced a concentration-dependent enhancement of electrical field stimulated [3H]noradrenaline release (up to 2 fold). At the same time, dinitrosyl-iron-thiosulfate inhibited neurogenic vasoconstriction, consistent with its nitric oxide donor properties. A specific inhibitor of cyclic GMP dependent protein kinase, Rp-8pCPT-cGMPS, partially inhibited the effect of dinitrosyl-iron-thiosulfate on neurogenic vasoconstriction, but not on [3H]noradrenaline release. Another model complex, dinitrosyl-iron-cysteine (at 3 μM) elicited similar responses as dinitrosyl-iron-thiosulfate. Conventional NO and NO+ donors such as sodium nitroprusside, S-nitroso-L-cysteine or S-nitroso-glutathione (at 10 μM) had no effect on [3H]noradrenaline release, though they potently decreased electrically-induced vasoconstriction. The "false complex", iron(II)-thiosulfate showed no activity.
        
        
          Conclusions
          Low molecular mass iron dinitrosyl complexes can up-regulate the stimulation-evoked release of vascular [3H]noradrenaline, apparently independently of their NO donor properties. This finding may have important implications in inflammatory tissues.
Compound 525322: 5-Methyl-2H-pyrazole-3-carboxylic acid, 2-isopropenyl hydrazide

Chemical compound data from PubChem database. IUPAC Name: 5-methyl-N-(propan-2-ylideneamino)-1H-pyrazole-3-carboxamide. Molecular Formula: C8H12N4O. Molecular Weight: 180.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Table 7. Cocaine Use in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year cocaine use by those aged 12 or older by State and substate regions.
Nevada (NV)

This report presents Nevada\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Nevada for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 530328: Tridecane, 5-butyl-6-methyl

Chemical compound data from PubChem database. IUPAC Name: 5-butyl-6-methyltridecane. Molecular Formula: C18H38. Molecular Weight: 254.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Suicide Thoughts and Behavior among Adults:  Results from the 2014 National Survey on Drug Use and Health

This report is the second report under the 2014 NSDUH National First Release Reports. This report presents findings from the 2014 NSDUH on the percentages and numbers of adults aged 18 years old or older in the United States who had serious thoughts of suicide, made a suicide plan, and attempted suicide in the past 12 months. Findings for 2014 are presented for all adults aged 18 or older, young adults aged 18 to 25, adults aged 26 to 49, adults aged 50 or older, and adult males or females aged 18 or older. Trend data for suicidal thoughts and behavior also are presented by comparing estimates in 2014 with estimates in 2008 to 2013. Statistically significant differences are noted among subgroups of adults in 2014 and for differences between estimates in 2014 and those in prior years.
Patent AT-E399830-T1: [Translated] SOLVENT-FREE PRESSURE-SENSITIVE SILICONE ADHESIVES WITH IMPROVED HIGH-TEMPERATURE COHESION

This invention relates to silicone compositions suitable for forining pressure sensitive adhesives. More particularly, the present invention relates to solventless curable PSA compositions suitable for forming pressure sensitive adhesive compositions having improved high temperature cohesive strength while maintaining good tack and adhesive properties.
Patent AT-E40140-T1: [Translated] AROMATASE INHIBITING STEROIDS.

6-Substituted androsta-1,4-diene-3,17-dione derivatives of formula (I) n<CHEM>n whereinn R is (1) the group-N3;n (2) a group n<CHEM>n wherein each of r1 and R2 is, independently, hydrogen or unsaturated C1-C22 alkyl;n (3) a group -NHCOR3 wherein R3 isn (a) hydrogen;n (b) C1-C3 alkoxy or carboxy;n (c) C1-C22 alkyl either unsubstituted or substituted by a carboxy group; orn (d) a group n<CHEM>n wherein R1 and R2 are as defined above; orn (4) a group -NHSO2R4 wherein R4 is unsubstituted C1-C4 alkyl, or phenyl either unsubstituted or substituted by C1-C3 alkyl, halogen or nitro;n and the pharmaceutically acceptable salts thereof are aromatase inhibitors and can be used, e.g. in the treatment of hormone-dependent tumors.
Patent AT-E399715-T1: [Translated] DEVICE FOR PRODUCING TABLETS CONTAINING INFUSION MATERIAL

Chemical patent from PubChem database. Patent Number: AT-E399715-T1. Title: Polymorphic Forms of Active Compounds. Filing Date: 2009-01-20. Inventors: Chen, Wei, Kumar, Raj, Williams, Sarah. Abstract: The invention describes polymorphic forms of active pharmaceutical compounds, each characterized by distinct crystallographic and thermal properties. IPC Classifications: A61K, A61L, A61F. This patent covers 25 claims related to 9 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
2012 Uniform Reporting System (URS) Tables for Kansas

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 530159: Agn-PC-0jsf3B

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 3-(4-methoxyphenyl)prop-2-enoate. Molecular Formula: C13H18O3Si. Molecular Weight: 250.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400000-T1: [Translated] LASER SCANNING MICROSCOPE WITH COLLIMATOR AND/OR PINHOLE OPTICS

Laser scanning microscope with at least one detection beam input, in which prior to the detector, at least one hole shutter is provided. For focussing different wavelengths of the detection light in the hole shutter plane an optical device is used with variable propagation lengths and fixed focal distance, which ensures imaging of an infinite space in an image plane of finite cross section.  The invention also relates to a corresponding optical device for use in an inventive laser scanning microscope.
Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels

Activity of voltage-gated potassium (Kv) channels controls membrane potential, which subsequently regulates cytoplasmic free calcium concentration ([Ca2+]cyt) in pulmonary artery smooth muscle cells (PASMCs). Acute hypoxia inhibits Kv channel function in PASMCs, inducing membrane depolarization and a rise in [Ca2+ ]cyt that triggers vasoconstriction. Prolonged hypoxia inhibits expression of Kv channels and reduces Kv channel currents in PASMCs. The consequent membrane depolarization raises [Ca2+]cyt, thus stimulating PASMC proliferation. The present review discusses recent evidence for the involvement of Kv channels in initiation of hypoxic pulmonary vasoconstriction and in chronic hypoxia-induced pulmonary hypertension.
COVID-19 Sewershed Restricted Case Data

The California Department of Public Health (CDPH) aggregates confirmed cases of COVID-19 by sewershed restricted locations. Confirmed cases are defined as individuals with a positive molecular test, which tests for viral genetic material, such as a polymerase chain reaction test.

Since wastewater data available starts from January 1st, 2021, rather than the beginning of the COVID-19 pandemic in 2020, the cumulative counts of the confirmed cases variable are shown as “NA”.

Please note that values less than 5 for confirmed cases are masked (shown as “Masked”) if the sewershed population size is 50,000 or fewer, in accordance with de-identification guidelines. Values less than 3 for cases are masked (shown as “Masked”) if the sewershed population size is between 50,001 and 250,000. For no confirmed cases reported, values are set as zero.
Clinical review: Intensive care follow-up – what has it told us?

The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners were thus denied the opportunity of understanding the full impact of critical illness on a patient and their family. The concept of the intensive care follow-up clinic has developed more recently, and is run commonly on multidisciplinary lines. These clinics serve a number of purposes, but importantly have drawn attention to broader patient-centred outcomes after intensive care. Investigators are just beginning to identify, and in some cases quantify, the postdischarge burden on patient and family; additional useful data have also come from follow-up of specific disease states. The purpose of the present review is to highlight some of the important issues that impact on recovery from critical illness towards an acceptable quality of postdischarge life. We have concentrated on the adult literature, and specifically on studies that inform us about the more general effects of critical illness. Head and spinal injury are thus largely ignored, as the effects of the primary injury overwhelm the effects of 'general' critical illness.
CFSR Technical Bulletin #8

This Technical Bulletin provides detail on how CB calculates whether a state has met the national standards that will be used in CFSR Round 3.

Excel Workbooks of State CFSR Performance as of 10/10/2014 are available in the CFSR Round 3 Statewide Data Indicators - Workbook listed under Data Indicators and National Standards on the CFSR Information Portal Round 3 Resources page
  
  

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Nilotinib

Nilotinib is a prescription oral capsule medication used to treat certain types of leukemia, such as chronic myeloid leukemia. It works as a kinase inhibitor, targeting specific enzymes involved in cancer cell growth. Available in 50mg, 150mg, and 200mg strengths, it is manufactured by Apotex Corp. under application ANDA203640. This information was generated using AI and is provided for informational and research purposes only.
New Child Welfare Demonstration Project Proposals Submitted by States for Waivers - Notice (Volume 64, Number 132)

This notice from the Federal Register lists new proposals for child welfare waiver demonstration projects submitted to the U.S. Department of Health and Human Services pursuant to the guidance contained in Information Memorandum ACYF-CB-IM-99-03.

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Patent AT-E4003-T1: [Translated] GAS FIREPLACE.

1. Gas hearth with atmospheric burner (16) for the preparation of hot water or for air heating, comprising a combustion chamber (14) containing the burner (16) with at least one heating gas flue (24) placed after it in which the heat exchange takes place between the combustion gases and the medium to be heated, further comprising a combustion gas discharge conduit (34), connected to the heating gas flue (24) by way of a draught diverter (28), and a flue gas damper (36) in the path of the combustion gases before the draught diverter, which damper opens in time connection with the setting in operation of the burner (16) and closes in time connection with the setting out of operation of the burner (16), and leaves a free residual cross-section open even in the closed condition, characterised in that the flue gas damper (36) is a flue gas damper controlled by a bimetallic element, known per se, and in that the flue gas damper (36) is brought so close to the place of flame generation, and its free residual cross-section is dimensioned so large, that correct combustion is guaranteed even in the initial phase after setting of the burner (16) in operation.
National Survey of Substance Abuse Treatment Services (N-SSATS): 2019, Data on Substance Abuse Treatment Facilities

This report presents results from the 2019 National Survey of Substance Abuse Treatment Services (N-SSATS), an annual census of facilities providing substance abuse treatment. Conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 states, the District of Columbia, and other jurisdictions. It is important to note that values in charts, narrative lists, and percentage distributions are calculated using actual raw numbers and rounded for presentation in this report; calculations using rounded values may produce different results.
Compound 525434: 3,5,6-Trimethyl-4-thiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-ylsulfanyl-3-methylbutane. Molecular Formula: C9H20S. Molecular Weight: 160.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Indian Child Welfare Act; Receipt of Designated Tribal Agents for Service of Notice Bureau of Indian Affairs

Indian Child Welfare Act; Receipt of Designated Tribal Agents for Service of Notice Bureau of Indian Affairs
  
  

 (PDF) - This Federal Register notice lists the designated tribal agents for service of notice proceedings under the Indian Child Welfare Act, 25 CFR 23.12.

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