AndreaBozzo/ceres-open-data-index huggingface dataset:
IFN-γ production in response to

IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or influenza virus. IFN-γ production in response to CII was similar in rheumatoid arthritis (RA) patients and healthy control individuals. The IFN-γ response to purified protein derivative and influenza virus was lower in RA patients, reflecting a general T-cell hyporesponsiveness in RA. After recalculating the response to CII taking this hyporesponsiveness into account the CII response was higher in RA patients, and was associated with human leucocyte antigen (HLA)-DRB1*0401 and HLA-DQA1*0301-DQB1*0302 (HLA-DQ8). Rheumatoid arthritis patients with elevated serum levels of immunoglobulin (Ig)G anti-CII antibodies had lower CII-induced IFN-γ production than patients with low anti-CII levels. The relative increase in CII-reactivity in RA patients as compared with healthy control individuals, and the association of a higher response with RA-associated HLA haplotypes, suggest the existence of a potentially pathogenic cellular reactivity against CII in RA.
Denver: Drug-Related Emergency Department Visits, 2004-2011 - All Misuse and Abuse

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving drug misuse or abuse in the Denver metropolitan area, covering 2004-2011. Drug misuse/abuse visits include the use of illicit drugs, nonmedical use of pharmaceuticals, underage drinking and visits where alcohol was combined with another drug.
Missouri: 2011-2012 NSDUH

This report presents Missouri\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer

Background
          We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal tissue from the same patient.
        
        
          Results
          Quantitative RT-PCR analysis of the expression of the EphB4 gene has shown that its expression is increased in 82% of tumour samples when compared with the matched normal tissue from the same patient. Using immunohistochemistry and Western analysis techniques with an EphB4-specific antibody, we also show that this receptor is expressed in the epithelial cells of the tumour tissue and either not at all, or in only low levels, in the normal tissue.
        
        
          Conclusion
          The results presented here supports the emerging idea that Eph receptors play a role in tumour formation and suggests that further elucidation of this signalling pathway may identify useful targets for cancer treatment therapies.
Compound 528323: Pyrazine, 3-methylthio-2-pentyl

Chemical compound data from PubChem database. IUPAC Name: 2-methylsulfanyl-3-pentylpyrazine. Molecular Formula: C10H16N2S. Molecular Weight: 196.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525254: N''-Benzyl-N,N,N',N'-tetramethyl-guanidine

Chemical compound data from PubChem database. IUPAC Name: 2-benzyl-1,1,3,3-tetramethylguanidine. Molecular Formula: C12H19N3. Molecular Weight: 205.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527256: Rosifoliol

Chemical compound data from PubChem database. IUPAC Name: 2-(4a,8-dimethyl-3,4,5,6,7,8-hexahydro-2H-naphthalen-2-yl)propan-2-ol. Molecular Formula: C15H26O. Molecular Weight: 222.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Comprehensive Care for Joint Replacement Model: Metropolitan Statistical Areas

The Comprehensive Care for Joint Replacement Model: Metropolitan Statistical Areas (MSAs) dataset presents MSAs that are participating in the CMS Innovation Center Comprehensive Care for Joint Replacement Model, a model to support better and more efficient care for beneficiaries undergoing the most common inpatient surgery for Medicare beneficiaries: hip and knee replacements. Participation in this model is designated by geographic area, specifically MSAs. The information contained in the dataset can include MSA identification number, MSA geographic name and associated county or counties.
Elk Creek Seismic Waveforms 2011 (Part 8 of 19)

Coal bursts (damaging seismic events in underground coal mines) pose a substantial threat to operations and mine workers. The underground coal mines in Colorado’s North Fork Valley (NFV) have experienced many coal bursts, often with distinct characteristics from those of other US coal mining regions. To better understand these events and manage their associated risks, the National Institute for Occupational Safety and Health undertook a long-term monitoring campaign at the Elk Creek Mine in the NFV. The monitoring efforts included a seismic network composed of both surface and underground sensors, borehole pressure cells (BPCs), instrumented support Cans, convergence monitors, ground condition surveys, and several other data sources. This dataset consists of the event waveform files from the seismic network for the 983,379 events that were detected during the monitoring campaign. The waveforms are stored in HDF5 files that are broken up by week. Within the HDF5 files, the data are organized by station id, event time, and channel. The amplitudes are velocity in meters/second.
 
This is download 16 of 48 and corresponds to the time range between March 7, 2011, and April 4, 2011.
Table 26. Had Serious Thoughts of Suicide in the Past Year among Persons Aged 18 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 26. Had Serious Thoughts of Suicide in the Past Year among Persons Aged 18 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Electrolytic ablation of the rat pancreas: a feasibility trial

Background
          Pancreatic cancer is a biologically aggressive disease with less than 20% of patients suitable for a "curative" surgical resection. This, combined with the poor 5-year survival indicates that effective palliative methods for symptom relief are required. Currently there are no ablative techniques to treat pancreatic cancer in clinical use. Tissue electrolysis is the delivery of a direct current between an anode and cathode to induce localised necrosis. Electrolysis has been shown to be safe and reliable in producing hepatic tissue and tumour ablation in animal models and in a limited number of patients. This study investigates the feasibility of using electrolysis to produce localised pancreatic necrosis in a healthy rat model.
        
        
          Method
          Ten rats were studied in total. Eight rats were treated with variable "doses" of coulombs, and the systemic and local effects were assessed; 2 rats were used as controls.
        
        
          Results
          Seven rats tolerated the procedure well without morbidity or mortality, and one died immediately post procedure. One control rat died on induction of anaesthesia. Serum amylase and glucose were not significantly affected.
        
        
          Conclusion
          Electrolysis in the rat pancreas produced localised necrosis and appears both safe, and reproducible. This novel technique could offer significant advantages for patients with unresectable pancreatic tumours. The next stage of the study is to assess pancreatic electrolysis in a pig model, prior to human pilot studies.
Hospital Cost Report Audited Data: 2015

This version of the Institutional Cost Report (ICR) has been audited by a Certified Public Accounting Firm. The ICR is a uniform report completed by New York State hospitals to report income, expenses, assets, liabilities, and statistics to the Department of Health (DOH). Under DOH regulations, (Part 86-1.2), Article 28 hospitals are required to file financial and statistical data with DOH annually. The data filed is part of the ICR and is received electronically through a secured network. This data is used to develop Medicaid rates, assist in the formulation of reimbursement methodologies, and analyze trends. For more information, check out: http://www.health.ny.gov/facilities/hospital/index.htm
Patent AT-E39954-T1: [Translated] ELECTROMOTORIAL REGULATORY AND CONTROL DRIVE, ESPECIALLY FOR INDUSTRIAL SEWING MACHINES.

An electromotive variable-speed and control drive particularly for use in industrial sewing machines and comprising a coupling coil casing radially surrounding a coupling-brake disk and a brake coil casing radially relocated towards the center. Both are positioned in the brake end shield. In order to avoid a sticking of the coupling-brake disk with high alternations and a delay of the break-down and build-up of the magnetic fields, a brake coil casing has been relocated radially so near to the center that it is situated within the brake pad in front of the armature ring. On the other hand, there is an undercut and a recess at the coupling coil casing and a recess at the disk flywheel which assures that no axial forces can occur at the radial gaps.
HCUP Kids' Inpatient Database (KID) - Restricted Access File

The Healthcare Cost and Utilization Project (HCUP) Kids' Inpatient Database (KID) is the largest publicly available all-payer pediatric inpatient care database in the United States, containing data from two to three million hospital stays each year. Its large sample size is ideal for developing national and regional estimates and enables analyses of rare conditions, such as congenital anomalies, as well as uncommon treatments, such as organ transplantation. Developed through a Federal-State-Industry partnership sponsored by the Agency for Healthcare Research and Quality, HCUP data inform decision making at the national, State, and community levels.

The KID is a sample of pediatric discharges from 4,000 U.S. hospitals in the HCUP State Inpatient Databases yielding approximately two to three million unweighted hospital discharges for newborns, children, and adolescents per year. About 10 percent of normal newborns and 80 percent of other neonatal and pediatric stays are selected from each hospital that is sampled for patients younger than 21 years of age. 

The KID contains clinical and resource use information included in a typical discharge abstract, with safeguards to protect the privacy of individual patients, physicians, and hospitals (as required by data sources). It includes discharge status, diagnoses, procedures, patient demographics (e.g., sex, age), expected source of primary payment (e.g., Medicare, Medicaid, private insurance, self-pay, and other insurance types), and hospital charges and cost.

Restricted access data files are available with a data use agreement and brief online security training.
2012 NSDUH: Estimating Mental Illness Among Adults In The United States: Revisions To 2008 Estimation Procedures

As part of the Mental Health Surveillance Study (MHSS), the Substance Abuse and Mental Health Services Administration (SAMHSA) conducted a clinical follow-up survey via telephone on a subsample of the National Survey on Drug Use and Health (NSDUH) adult respondents from 2008 to 2012 to assess the prevalence of selected mental disorders. The purpose of this clinical data collection was to use the data to develop statistical models that would provide national and state estimates of serious mental illness (SMI) when combined with NSDUH data.This report outlines the revisions made to the 2008 models to predict SMI.
CDPHE Composite Selected Health Outcome Dataset (Census Tract)

This census tract geography dataset contains eight selected 2011-2015 health outcome rates calculated at the census tract geography for all of the census tracts in Colorado: (Asthma Hospitalizations, Diabetes Hospitalizations, Heart Disease Mortality, Influenza Hospitalizations, Low Weight Birth, Motor Vehicle Accident Mortality, Suicide Mortality, and Teen Fertility).  The rates contained in this dataset represent 2011-2015 5-Year Averages and include the 95% confidence interval for each census tract rate as well as the Colorado state average.  Published rates that have large confidence intervals should be interpreted with caution.  This dataset is assembled and maintained annually by the Colorado Department of Public Health and Environment.
Compound 529628: Isopropyl(dimethyl)(tetradecyloxy)silane

Chemical compound data from PubChem database. IUPAC Name: 2-ethyl-1,3-oxathiolane. Molecular Formula: C5H10OS. Molecular Weight: 118.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Oregon AFCARS Assessment Review, 2013

This webpage includes the documentation from Oregon's Adoption and Foster Care Analysis and Reporting System (AFCARS) assessment review for fiscal year 2013:

AFCARS Assessment Review Letter

AFCARS Assessment Review Report

Tab A - Detailed Findings

Findings Instructions

Section I

AFCARS Assessment Review Findings - General Requirement

Section II

AFCARS Assessment Review Findings - Foster Care and Adoption Elements

Section III

AFCARS Case File Summary Report

AFCARS Assessment Review Case File Findings - Foster Care and Adoption Elements

Tab B - AFCARS Improvement Plan

Improvement Plan Instructions

Section I

AFCARS Assessment Review Improvement Plan - General Requirements

Section II

AFCARS Assessment Review Improvement Plan - Foster Care and Adoption Elements

Metadata-only record linking to the original dataset. Open original dataset below.
Behavioral Interventions to Advance Self-Sufficiency (BIAS)

The Behavioral Interventions to Advance Self-Sufficiency (BIAS) project was the first major opportunity to use a behavioral economic lens to examine programs in the United States that serve families who have low incomes.  Sponsored by the Office of Planning, Research, and Evaluation (OPRE) in the Administration for Children and Families (ACF) in the U.S. Department of Health and Human Services and led by MDRC, the project applied behavioral insights to issues related to the operations, implementation, and efficacy of social service programs and policies. The goal was to learn how tools from behavioral science can be used to deliver programs more effectively and, ultimately, improve the well-being of children, adults, and families with low incomes.

<b>Units of Response: </b>Unavailable

<b>Type of Data: </b>Administrative

<b>Tribal Data: </b>Unavailable

<b>Periodicity: </b>One-time

<b>Demographic Indicators: </b>Ethnicity;Sex

<b>SORN: </b>https://www.federalregister.gov/documents/2022/09/19/2022-20139/privacy-act-of-1974-system-of-records

<b>Data Use Agreement: </b>Not Applicable

<b>Data Use Agreement Location: </b>https://www.openicpsr.org/openicpsr/information?projectId=100389&versionNumber=V1&title=Behavioral%20Interventions%20to%20Advance%20Self-Sufficiency%20Project

<b>Granularity: </b>Individual

<b>Spatial: </b>Cities;States

<b>Geocoding: </b>State
Performance of the score systems Acute Physiology and Chronic Health Evaluation II and III at an interdisciplinary intensive care unit, after customization

Background:
          Mortality predictions calculated using scoring scales are often not accurate in populations other than those in which the scales were developed because of differences in case-mix. The present study investigates the effect of first-level customization, using a logistic regression technique, on discrimination and calibration of the Acute Physiology and Chronic Health Evaluation (APACHE) II and III scales.
        
        
          Method:
          Probabilities of hospital death for patients were estimated by applying APACHE II and III and comparing these with observed outcomes. Using the split sample technique, a customized model to predict outcome was developed by logistic regression. The overall goodness-of-fit of the original and the customized models was assessed.
        
        
          Results:
          Of 3383 consecutive intensive care unit (ICU) admissions over 3 years, 2795 patients could be analyzed, and were split randomly into development and validation samples. The discriminative powers of APACHE II and III were unchanged by customization (areas under the receiver operating characteristic [ROC] curve 0.82 and 0.85, respectively). Hosmer-Lemeshow goodness-of-fit tests showed good calibration for APACHE II, but insufficient calibration for APACHE III. Customization improved calibration for both models, with a good fit for APACHE III as well. However, fit was different for various subgroups.
        
        
          Conclusions:
          The overall goodness-of-fit of APACHE III mortality prediction was improved significantly by customization, but uniformity of fit in different subgroups was not achieved. Therefore, application of the customized model provides no advantage, because differences in case-mix still limit comparisons of quality of care.
Chromosome 4q;10q translocations; Comparison with different ethnic populations and FSHD patients

Background
          Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder characterized by the weakness of facial, shoulder-girdle and upper arm muscles. Most patients with FSHD have fewer numbers of tandem repeated 3.3-kb KpnI units on chromosome 4q35. Chromosome 10q26 contains highly homologous KpnI repeats, and inter-chromosomal translocation has been reported.
        
        
          Methods
          To clarify the influence on the deletion of the repeats, we surveyed three different ethnic populations and FSHD patients using the BglII/BlnI dosage test.
        
        
          Results
          The frequency of translocation in 153 Japanese, 124 Korean, 114 Chinese healthy individuals and 56 Japanese 4q35-FSHD patients were 27.5%, 29.8%, 19.3%, and 32.1%, respectively. The ratio of '4 on 10' (trisomy and quatrosomy of chromosome 4) was higher than that of '10 on 4' (nullsomy and monosomy of chromosome 4) in all populations.
        
        
          Conclusions
          The inter-chromosomal exchange was frequently observed in all four populations we examined, and no significant difference was observed between healthy and diseased groups.
Compound 525158: Glycerol-tetrapropylene glycol ether, triacetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-(2,3-diacetyloxypropoxy)propoxy]propoxy]propoxy]propyl acetate. Molecular Formula: C21H38O10. Molecular Weight: 450.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525824: N,N-Dimethyl-N'-(3-chlorophenyl)-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(3-chlorophenyl)-N,N-dimethylpropanimidamide. Molecular Formula: C11H15ClN2. Molecular Weight: 210.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529443: Benzene, 2,3-dimethylpentyl

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethylpentylbenzene. Molecular Formula: C13H20. Molecular Weight: 176.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525274: N'-(4-iodo-phenyl)-N,N-dimethyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(3-iodophenyl)-N,N-dimethylethanimidamide. Molecular Formula: C10H13IN2. Molecular Weight: 288.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526839: 11-Hydroxy-stearic acid, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 11-[tert-butyl(dimethyl)silyl]oxyoctadecanoate. Molecular Formula: C25H52O3Si. Molecular Weight: 428.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Potential role and chronology of abnormal expression of the Deleted in Colon Cancer (DCC) and the p53 proteins in the development of gastric cancer

Background
          Loss of activity of tumor suppressor genes is considered a fundamental step in a genetic model of carcinogenesis. Altered expression of the p53 and the Deleted in Colon Cancer (DCC) proteins has been described in gastric cancer and this event may have a role in the development of the disease. According to this hypothesis, we investigated the p53 and the DCC proteins expression in different stages of gastric carcinomas.
        
        
          Methods
          An immunohistochemical analysis for detection of p53 and DCC proteins expression was performed in tumor tissue samples of patients with UICC stage I and II gastric cancer. For the purpose of the analysis, the staining results were related to the pathologic data and compared between stage categories.
        
        
          Results
          Ninety-four cases of gastric cancer were analyzed. Disease stage categories were pT1N0 in 23 cases, pT2N0 in 20 cases, pT3N0 in 20 cases and pT1-3 with nodal involvment in 31 cases. Stage pT1-2N0 tumors maintained a positive DCC expression while it was abolished in pT3N0 tumors (p <.001). A significant higher proportion of patients with N2 nodal involvement showed DCC negative tumors. In muscular-invading tumors (pT2-3N0) the majority of cases showed p53 overexpression, whereas a significantly higher proportion of cases confined into the mucosa (pT1N0) showed p53 negative tumors. Also, a higher frequency of p53 overexpression was detected in cases with N1 and N2 metastatic lymphnodal involvement.
        
        
          Conclusions
          Altered expression of both DCC and p53 proteins is detectable in gastric carcinomas. It seems that loss of wild-type p53 gene function and consequent p53 overexpression may be involved in early stages of tumor progression while DCC abnormalities are a late event.