AndreaBozzo/ceres-open-data-index huggingface dataset:
Prominent medical journals often provide insufficient information to assess the validity of studies with negative results

Background
          Physicians reading the medical literature attempt to determine whether research studies are valid. However, articles with negative results may not provide sufficient information to allow physicians to properly assess validity.
        
        
          Methods
          We analyzed all original research articles with negative results published in 1997 in the weekly journals BMJ, JAMA, Lancet, and New England Journal of Medicine as well as those published in the 1997 and 1998 issues of the bimonthly Annals of Internal Medicine (N = 234). Our primary objective was to quantify the proportion of studies with negative results that comment on power and present confidence intervals. Secondary outcomes were to quantify the proportion of these studies with a specified effect size and a defined primary outcome. Stratified analyses by study design were also performed.
        
        
          Results
          Only 30% of the articles with negative results comment on power. The reporting of power (range: 15%-52%) and confidence intervals (range: 55–81%) varied significantly among journals. Observational studies of etiology/risk factors addressed power less frequently (15%, 95% CI, 8–21%) than did clinical trials (56%, 95% CI, 46–67%, p < 0.001). While 87% of articles with power calculations specified an effect size the authors sought to detect, a minority gave a rationale for the effect size. Only half of the studies with negative results clearly defined a primary outcome.
        
        
          Conclusion
          Prominent medical journals often provide insufficient information to assess the validity of studies with negative results.
Medicare Fee for Service (FFS) claims (100%) – Vision and Eye Health Surveillance

2014-2019. This dataset is a de-identified summary table of vision and eye health data indicators from Medicare claims, stratified by all available combinations of age group, race/ethnicity, gender, and state. Medicare claims for VEHSS includes beneficiaries who were fully enrolled in Medicare Part B Fee-for-Service (FFS) for the duration of the year. Medicare claims provide a convenience sample that includes approximately 30 million individuals annually, which represents nearly 89% of the US population aged 65 and older and 3.3% of the US population younger than 65, including persons disabled due to blindness. Medicare data for VEHSS include Service Utilization and Medical Diagnoses indicators. Data were suppressed for de-identification to ensure protection of patient privacy. Data will be updated as it becomes available. Detailed information on VEHSS Medicare analyses can be found on the VEHSS Medicare webpage (cdc.gov/visionhealth/vehss/data/claims/medicare.html). Information on available Medicare claims data can be found on the ResDac website (www.resdac.org). The VEHSS Medicare dataset was last updated May 2023.
Ohio (OH)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Ohio overall and for substate regions within Ohio. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
​Profile of Enrolled Medi-Cal Fee-for-Service (FFS) Providers

The dataset provides basic information of the FFS providers enrolled in the Medi-Cal program as of March 1, 2025.  The data was retrieved from the Provider Master File (PMF), which has been used in the claims payment process and maintained by the Provider Enrollment Division (PED).  The Variables in the dataset include provider number, name, type, specialty, geographic information, etc.  This dataset does not include the Managed Care providers.
Compound 526282: 1,3,7-Tribromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,3,7-tribromodibenzofuran. Molecular Formula: C12H5Br3O. Molecular Weight: 404.88. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

Hepatitis C virus (HCV) is an important human pathogen that affects ∼100 million people worldwide. Its RNA genome codes for a polyprotein, which is cleaved by viral and cellular proteases to produce at least 10 mature viral protein products. We report here the discovery of a novel HCV protein synthesized by ribosomal frameshift. This protein, which we named the F protein, is synthesized from the initiation codon of the polyprotein sequence followed by ribosomal frameshift into the –2/+1 reading frame. This ribosomal frameshift requires only codons 8–14 of the core protein-coding sequence, and the shift junction is located at or near codon 11. An F protein analog synthesized in vitro reacted with the sera of HCV patients but not with the sera of hepatitis B patients, indicating the expression of the F protein during natural HCV infection. This unexpected finding may open new avenues for the development of anti-HCV drugs.
Assessing the molecular genetics of attention networks

Background
          Current efforts to study the genetic underpinnings of higher brain functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many cognitive concepts for which there is a single word (e.g. attention) have been shown to be related to several anatomical networks. Recently, we have developed an Attention Network Test (ANT) that provides a separate measure for each of three anatomically defined attention networks.
        
        
          Results
          In this study we have measured the efficiency of neural networks related to aspects of attention using the ANT in a population of 200 adult subjects. We then examined genetic polymorphisms in four candidate genes (DRD4, DAT, COMT and MAOA) that have been shown to contribute to the risk of developing various psychiatric disorders where attention is disrupted. We find modest associations of several polymorphisms with the efficiency of executive attention but not with overall performance measures such as reaction time.
        
        
          Conclusions
          These results suggest that genetic variation may underlie inter-subject variation in the efficiency of executive attention. This study also shows that genetic influences on executive attention may be specific to certain anatomical networks rather than affecting performance in a global or non-specific manner. Lastly, this study further validates the ANT as an endophenotypic assay suitable for assessing how genes influence certain anatomical networks that may be disrupted in various psychiatric disorders.
Compound 527606: 4-Penten-2-ol, dibromoacetate

Chemical compound data from PubChem database. IUPAC Name: pent-4-en-2-yl 2,2-dibromoacetate. Molecular Formula: C7H10Br2O2. Molecular Weight: 285.96. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525781: 2-Hexyl-4,5-dimethyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2-hexyl-4,5-dimethyl-1,3-oxazole. Molecular Formula: C11H19NO. Molecular Weight: 181.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Federal NYTD Reviewer Opportunity

The National Youth in Transition Database (NYTD) is a federal reporting system that collects information on youth transitioning out of foster care. States administering the John H. Chafee Foster Care Program for Successful Transition to Adulthood (Chafee) must report on the services provided to young people and also conduct a survey using a cohort methodology at ages 17, 19, and 21. Recognizing the integral role of young adults in successfully designing services and implementing a survey for young people, the Children’s Bureau has engaged young adults through the NYTD Reviewer program to guide this work. NYTD Reviewers are between the ages of 18 and 28, have lived experience with the child welfare system, and are interested in the use of data to inform system improvements. Three to four NYTD Reviewers participate as members of the federal monitoring team for each onsite review.

NYTD is an opportunity to engage young people as partners in data collection, analysis, dissemination, and the use of data. As a member of the Federal Review Team, a NYTD Reviewer participates in all aspects of the review, including pre-onsite phase preparations, onsite review activities, and providing input on the Final Report findings and NYTD Improvement Plan. The following resources provide additional information about the qualifications and responsibilities of NYTD Reviewers:

On behalf of the Children’s Bureau, JBS International, Inc.'s Child Welfare Compliance Reviews Team (CWCRT) maintains a national pool of NYTD Reviewers to support the Children’s Bureau in administering the federal NYTD Reviews. Given the highly technical nature of the NYTD Review process, young people gain knowledge by participating in a training for which they are compensated, and for which travel costs are covered. CWCRT also conducts other skills-based trainings periodically as needed. NYTD Reviewers receive reimbursement for participating in trainings, reviews, and other NYTD-related work. They also receive reimbursement for travel expenses, and a per diem rate for meals and incidental expenses. The following resources provide additional information for those interested in serving as a NYTD Reviewer:

If you believe you are qualified to participate, please email CWCRT at cw-mail@jbsinternational.com for a NYTD Reviewer application packet.

Metadata-only record linking to the original dataset. Open original dataset below.
2011 CMHS Uniform Reporting System (URS) Output Tables for Hawaii

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 530633: Valeric acid, 2,7-dimethyloct-7-en-5-yn-4-yl ester

Chemical compound data from PubChem database. IUPAC Name: 2,7-dimethyloct-7-en-5-yn-4-yl pentanoate. Molecular Formula: C15H24O2. Molecular Weight: 236.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400130-T1: [Translated] METHOD AND SYSTEM FOR CONTROLLING THE SCOPE OF DELEGATION OF AUTHENTICATION DATA

Methods and systems are provided for controlling the scope of delegation of authentication credentials within a network environment. A server (210) is configured to provide a trusted third-party (206) with a ticket authenticating the server, information about a target service (212,214) that a server seeks to access on behalf of the client, and a service ticket associated with the client. This service ticket may be provided by the client (202) or may be a previously granted service ticket granted to the server (210) for itself in the name of the client. The trusted third-party grants a new service ticket to access the target service (212,214) to the server (210), in the client's name, if such delegation is permitted according to delegation constraints associated with the client.
Compound 529713: Methyl 11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-2-ene-9-carboxylate

Chemical compound data from PubChem database. IUPAC Name: methyl 11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-2-ene-9-carboxylate. Molecular Formula: C20H24O4. Molecular Weight: 328.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Understanding Post Adoption and Guardianship Instability for Children and Youth Who Exit Foster Care (PAGI): The NSCAW Adoption Study

The Survey of National Survey of Child and Adolescent Well-Being (NSCAW) Adopted Youth, Young Adults, Adults, and Adoptive Parents (hereafter referred to as “The NSCAW Adoption Study”) seeks to understand the extent of post adoption instability events that occur in families who have adopted children who have exited the foster care system. Post adoption instability refers to situations in which children who exit foster care to adoptive homes no longer reside with their adoptive parents and includes formal events, such as a child’s reentry into the foster care system, or informal events, such as a child going to live with a grandparent or running away. A second objective is to understand risk and protective factors associated with post adoption instability. The study conducted web or telephone surveys with adopted youth, young adults, and adults as well as their adoptive parents who were participants in the first or second cohort of the National Survey of Child and Adolescent Well-Being (NSCAW I, II; OMB #0970-0202).

Investigators: Heather Ringeisen, PhD
RTI International Research Triangle Park, NC

Rose Domanico, MA
RTI International Research Triangle Park, NC

Nancy Rolock, PhD
Case Western Reserve University Cleveland, OH

Kevin White, PhD
East Carolina University Greenville, NC

Stephen Tueller, PhD
RTI International Research Triangle Park, NC

Leyla Stambaugh, PhD
RTI International Research Triangle Park, NC
Compound 526881: 2-[2-(2-Isopentoxyethoxy)ethoxy]ethyl TMS ether

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-[2-[2-(3-methylbutoxy)ethoxy]ethoxy]ethoxy]silane. Molecular Formula: C14H32O4Si. Molecular Weight: 292.49. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
PubMed total records by publication year

Yearly citation totals from each year of the MEDLINE/PubMed Baseline referencing citations back to year 1781.  These totals may increase over time for a particular year as new citations are added.  For example, 25 citations were listed for the year 1800 in the 2018 MEDLINE/PubMed Baseline, while the 2019 Baseline includes 387 citations for that year.
Compound 528922: 3-Methylideneocta-1,5-diene

Chemical compound data from PubChem database. IUPAC Name: 3-methylideneocta-1,5-diene. Molecular Formula: C9H14. Molecular Weight: 122.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Percentage of Drivers and Front Seat Passengers Wearing Seat Belts, 2012 & 2014, Region 10 - Seattle

Source for 2012 national data: National Occupant Protection Use Survey (NOPUS), 2012. Source for 2014 national data: National Occupant Protection Use Survey (NOPUS), 2014.  Source for 2012 state data: State Observational Survey of Seat Belt Use, 2012. Source for 2014 state data: Seat Belt Use in 2014- Use Rates in the States and Territories
2015 CMHS Uniform Reporting System (URS) Table for Arkansas

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Arkansas. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
US Census Methodology

2010-2018; 2019. US Census Annual Estimates of the Resident Population for Selected Age Groups by Sex for the United States. The estimates for the 2010-2018 dataset are based on the 2010 Census and reflect changes to the April 1, 2010 population due to the Count Question Resolution program and geographic program revisions. Median age is calculated based on single year of age. The estimates for 2019 are based on a one-year dataset that was published on the US Census website in 2021. For population estimates methodology statements, see http://www.census.gov/popest/methodology/index.html.
Weekly Cumulative Influenza Vaccination Coverage Comparison between Current and Previous Season, Children 6 Months through 17 Years, United States

Weekly Cumulative Influenza Vaccination Coverage Comparison between Current and Previous Season, Children 6 Months through 17 Years, United States 

• Influenza vaccination coverage among children is assessed through the National Immunization Survey-Flu (NIS-Flu) annually, providing weekly influenza vaccination coverage estimates for children 6 months–17 years based upon parental report. (https://www.cdc.gov/vaccines/imz-managers/nis/about.html) 

o NIS-Flu is a national random-digit-dialed cellular telephone survey of households conducted during the flu season (October-June). 

• Additional information about NIS-Flu methods and estimates from the 2019-2020 season are available at: https://www.cdc.gov/flu/fluvaxview/coverage-1920estimates.htm. Final estimates for prior seasons and other flu vaccination data are available at CDC’s FluVaxView.:  https://www.cdc.gov/flu/fluvaxview/index.htm.
The average cost of measles cases and adverse events following vaccination in industrialised countries

Background
          Even though the annual incidence rate of measles has dramatically decreased in industrialised countries since the implementation of universal immunisation programmes, cases continue to occur in countries where endemic measles transmission has been interrupted and in countries where adequate levels of immunisation coverage have not been maintained. The objective of this study is to develop a model to estimate the average cost per measles case and per adverse event following measles immunisation using the Netherlands (NL), the United Kingdom (UK) and Canada as examples.
        
        
          Methods
          Parameter estimates were based on a review of the published literature. A decision tree was built to represent the complications associated with measles cases and adverse events following imminisation. Monte-Carlo Simulation techniques were used to account for uncertainty.
        
        
          Results
          From the perspective of society, we estimated the average cost per measles case to be US$276, US$307 and US$254 for the NL, the UK and Canada, respectively, and the average cost of adverse events following immunisation per vaccinee to be US$1.43, US$1.93 and US$1.51 for the NL, UK and Canada, respectively.
        
        
          Conclusions
          These average cost estimates could be combined with incidence estimates and costs of immunisation programmes to provide estimates of the cost of measles to industrialised countries. Such estimates could be used as a basis to estimate the potential economic gains of global measles eradication.
Why the fair innings argument is not persuasive

The fair innings argument (FIA) is frequently put forward as a justification for denying elderly patients treatment when they are in competition with younger patients and resources are scarce. In this paper I will examine some arguments that are used to support the FIA. My conclusion will be that they do not stand up to scrutiny and therefore, the FIA should not be used to justify the denial of treatment to elderly patients, or to support rationing of health care by age.
        There are six issues arising out of the FIA which are to be addressed. First, the implication that there is such a thing as a fair share of life. Second, whether it makes sense to talk of a fair share of resources in the context of health care and the FIA. Third, that 'fairness' is usually only mentioned with regard to the length of a person's life, and not to any other aspect of it. Fourth, if it is sensible to discuss the merits of the FIA without taking account of the 'all other things being equal' argument. Fifth, the difference between what is unfair and what is unfortunate. Finally, that it is tragic if a young person dies, but only unfortunate if an elderly person does.
Compound 527117: Hex-2-enyl 2-methylpropanoate

Chemical compound data from PubChem database. IUPAC Name: hex-2-enyl 2-methylpropanoate. Molecular Formula: C10H18O2. Molecular Weight: 170.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400275-T1: [Translated] ADENOSINE A2A RECEPTOR ANTAGONISTS FOR THE TREATMENT OF WORST LEGS SYNDROME OR NOcturnal MYOCLONUS

Chemical patent from PubChem database. Patent Number: AT-E400275-T1. Title: Bioactive Compound and Applications. Filing Date: 2014-04-24. Inventors: Rodriguez, Juan, White, Jennifer. Abstract: A bioactive compound and its applications in pharmaceutical and agricultural fields are described. The compound exhibits significant biological activi... IPC Classifications: B01J, C07C, C07D. This patent covers 24 claims related to 2 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
The Child Abuse Prevention and Treatment Act: 40 Years of Safeguarding America's Children

Passage of the Child Abuse Prevention and Treatment Act (CAPTA) in 1974 marked the Nation's first major step forward in addressing issues related to child maltreatment. To commemorate CAPTA's 40th anniversary, the Children's Bureau and its Office on Child Abuse and Neglect have developed The Child Abuse Prevention and Treatment Act: 40 Years of Safeguarding America's Children.

This online publication combines historical source materials with contemporary reflections on the impact of CAPTA from leaders in the field. This will be an invaluable resource to policymakers, practitioners, researchers, and students in the fields of child protection, child welfare, and social services, as well as all those interested in the story of child protection in the United States.

Metadata-only record linking to the original dataset. Open original dataset below.