AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E400838-T1: [Translated] LIGHT-CURING AND HEAT-CURING RESIN COMPOSITION

A photocurable and thermosetting resin composition comprises (A) an actinic energy ray-curable resin having at least one structure represented by the following general formula (1), (B) a photopolymerization initiator, (C) a diluent, and (D) a thermosetting component. <CHEM> wherein R<1> represents a hydrogen atom or an alkyl group of 1 to 6 carbon atoms, R<2>, R<3> and R<4> independently represent a hydrogen atom, an alkyl group of 1 to 6 carbon atoms, an aryl group, an aralkyl group, a cyano group, a fluorine atom, or a furyl group, and X represents a polybasic acid anhydride residue.
Compound 526970: Phenyl-3-nitrophenylacetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(3-nitrophenyl)-2-phenylacetate. Molecular Formula: C15H13NO4. Molecular Weight: 271.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NCHS - Age-adjusted Death Rates for Selected Major Causes of Death

This dataset of U.S. mortality trends since 1900 highlights trends in age-adjusted death rates for five selected major causes of death.

Age-adjusted death rates (deaths per 100,000) after 1998 are calculated based on the 2000 U.S. standard population. Populations used for computing death rates for 2011–2017 are postcensal estimates based on the 2010 census, estimated as of July 1, 2010. Rates for census years are based on populations enumerated in the corresponding censuses. Rates for noncensus years between 2000 and 2010 are revised using updated intercensal population estimates and may differ from rates previously published. Data on age-adjusted death rates prior to 1999 are taken from historical data (see References below).

Revisions to the International Classification of Diseases (ICD) over time may result in discontinuities in cause-of-death trends.

SOURCES

CDC/NCHS, National Vital Statistics System, historical data, 1900-1998 (see https://www.cdc.gov/nchs/nvss/mortality_historical_data.htm); CDC/NCHS, National Vital Statistics System, mortality data (see http://www.cdc.gov/nchs/deaths.htm); and CDC WONDER (see http://wonder.cdc.gov).

REFERENCES

1. National Center for Health Statistics, Data Warehouse. Comparability of cause-of-death between ICD revisions. 2008. Available from: http://www.cdc.gov/nchs/nvss/mortality/comparability_icd.htm.

2. National Center for Health Statistics. Vital statistics data available. Mortality multiple cause files. Hyattsville, MD: National Center for Health Statistics. Available from: https://www.cdc.gov/nchs/data_access/vitalstatsonline.htm.

3. Kochanek KD, Murphy SL, Xu JQ, Arias E. Deaths: Final data for 2017. National Vital Statistics Reports; vol 68 no 9. Hyattsville, MD: National Center for Health Statistics. 2019. Available from: https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_09-508.pdf.

4. Arias E, Xu JQ. United States life tables, 2017. National Vital Statistics Reports; vol 68 no 7. Hyattsville, MD: National Center for Health Statistics. 2019. Available from: https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_07-508.pdf.

5. National Center for Health Statistics. Historical Data, 1900-1998. 2009. Available from: https://www.cdc.gov/nchs/nvss/mortality_historical_data.htm.
Compound 529637: Furylmethyl 2-methyl-3-furyl disulfide

Chemical compound data from PubChem database. IUPAC Name: 2-[(furan-3-yldisulfanyl)methyl]furan. Molecular Formula: C9H8O2S2. Molecular Weight: 212.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527203: 2,2,2-Trichloroethyl heptanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2,2-trichloroethyl heptanoate. Molecular Formula: C9H15Cl3O2. Molecular Weight: 261.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
South Dakota (SD)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for South Dakota overall and for substate regions within South Dakota. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Comparative analysis of somitogenesis related genes of the

Background
          Members of a class of bHLH transcription factors, namely the hairy (h), Enhancer of split (E(spl)) and hairy-related with YRPW motif (hey) (h/E(spl)/hey) genes are involved in vertebrate somitogenesis and some of them show cycling expression. By sequence comparison, identified orthologues of cycling somitogenesis genes from higher vertebrates do not show an appropriate expression pattern in zebrafish. The zebrafish genomic sequence is not available yet but the genome of Fugu rubripes was recently published. To allow comparative analysis, the currently known Her proteins from zebrafish were used to screen the genomic sequence database of Fugu rubripes.
        
        
          Results
          20 h/E(spl)/hey-related genes were identified in Fugu, which is twice the number of corresponding zebrafish genes known so far. A novel class of c-Hairy proteins was identified in the genomes of Fugu and Tetraodon. A screen of the human genome database with the Fugu proteins yielded 10 h/E(spl)/hey-related genes. By analysing the upstream sequences of the c-hairy class genes in zebrafish, Fugu and Tetraodon highly similar sequence stretches were identified that harbour Suppressor of hairless paired binding sites (SPS). This motif was also discovered in the upstream sequences of the her1 gene in the examined fish species. Here, the Su(h) sites are separated by longer intervening sequences.
        
        
          Conclusions
          Our study indicates that not all her homologues in zebrafish have been isolated. Comparison to the human genome suggests a selective duplication of h/E(spl) genes in pufferfish or loss of members of these genes during evolution to the human lineage.
Patent AT-E399615-T1: [Translated] DEVICE FOR MARKING OBJECTS USING LASER BEAMS

A device for inscribing an object, including a laser emitter for emitting at least one laser beam and an arrangement of diverting means for directing the at least one laser beam from the exit point of the laser emitter to a focal point on the object, wherein, in one embodiment, each laser beam is assigned to a diverting means, depending on the exit angle of the laser beam from the laser emitter so that at least two sides of the object my be inscribed and, in another embodiment, the diverting means is movable so that at least two sides of the object may be inscribed by movably arranging the diverting means.
2013 CMHS Uniform Reporting System (URS) Table for Ohio

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Ohio for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Organ Procurement Organizations, Eye Banks and Tissue Banks Information

This dataset contains the names, contact information, and county location for the federally authorized Organ Procurement Organizations (OPOs), as well as the New York State regulated Eye Banks and Tissue Banks. These organizations work closely with the Department of Health (DOH) to educate the public regarding the need for organ and tissue donation and to facilitate the enrollment of individuals in the New York State Donate Life Organ and Tissue Donor Registry. The contact information and service areas provided in this dataset are subject to change without DOH’s knowledge since the data is provided by independent OPOs, Eye Banks and Tissue Banks.  For more information please visit, http://www.health.ny.gov/professionals/patients/donation/organ/. The "About" tab contains additional details concerning this dataset.
Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11

Background
          In asthma and other allergic disorders, the activation of mast cells by IgE and antigen induces the cells to release histamine and other mediators of inflammation, as well as to produce certain cytokines and chemokines. To search for new mast cell products, we used complementary DNA microarrays to analyze gene expression in human umbilical cord blood-derived mast cells stimulated via the high-affinity IgE receptor (FcεRI).
        
        
          Results
          One to two hours after FcεRI-dependent stimulation, more than 2,400 genes (about half of which are of unknown function) exhibited 2–200 fold changes in expression. The transcriptional program included changes in the expression of IL-11 and at least 30 other cytokines and chemokines. Human mast cells secreted 130–529 pg of IL-11/106 cells by 6 h after stimulation with anti-IgE.
        
        
          Conclusion
          Our initial analysis of the transcriptional program induced in in vitro-derived human mast cells stimulated via the FcεRI has identified many products that heretofore have not been associated with this cell type, but which may significantly influence mast cell function in IgE-associated host responses. We also have demonstrated that mast cells stimulated via the FcεRI can secrete IL-11. Based on the previously reported biological effects of IL-11, our results suggest that production of IL-11 may represent one link between IgE-dependent mast cell activation in subjects with allergic asthma and the development of a spectrum of structural changes in the airways of these individuals; such changes, collectively termed "airway remodeling," can constitute an important long term consequence of asthma.
From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development

The hedgehog signalling pathway has been implicated in many different processes in fly and vertebrate development. It is now known that the hedgehog cascade is crucial for the patterning of the early respiratory system. Hedgehog signalling in the lung involves Gli transcription proteins, but their potential downstream target genes have yet to be identified. Bmp4 and Fgf10 have been shown to regulate lung branching morphogenesis but seem not to be targets of hedgehog signalling.
Compound 525179: Pentapropyleme glycol, monoallyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 1-[1-[1-[1-(1-prop-2-enoxypropan-2-yloxy)propan-2-yloxy]propan-2-yloxy]propan-2-yloxy]propan-2-yl acetate. Molecular Formula: C20H38O7. Molecular Weight: 390.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
List of Serials Indexed for Online Users (LSIOU)

The List of Serials Indexed for Online Users (LSIOU) provides bibliographic information for all journals whose articles were ever indexed over time with the MeSH® vocabulary and cited in MEDLINE®, the backbone of the NLM PubMed® database. It includes titles that ceased publication, changed titles, or are no longer indexed. More detailed bibliographic data and information about indexing coverage for serials cited in MEDLINE/PubMed can be found in LocatorPlus Catalog®, the NLM online catalog, and the NLM Catalog, an Entrez database.
Compound 526351: 3,4-Dibromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 3,4-dibromodibenzofuran. Molecular Formula: C12H6Br2O. Molecular Weight: 325.98. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Adoption Data 2010

This page includes reports on state-specific adoption statistics for fiscal year 2010.

Receiving Adoption Subsidy: 10/1/2009 - 9/30/2010
Adoptive Family Structure: 10/1/2009 - 9/30/2010
Age at Adoption Finalization: 10/1/2009 - 9/30/2010
Prior Relationship of Adoptive Parent(s) to Child: 10/1/2009 - 9/30/2010
Race/Ethnicity of Public Agency Children Adopted: 10/1/2009 - 9/30/2010
Sex of Public Agency Children Adopted: 10/1/2009 - 9/30/2010
Child is Identified as a Special Needs Adoption: 10/1/2009 - 9/30/2010
Time between Termination of Parental Rights (TPR) and Adoption Finalization: 10/1/2009 - 9/30/2010

Metadata-only record linking to the original dataset. Open original dataset below.
Chicago: Drug-Related Emergency Department Visits, 2004-2011 - Nonmedical Use of Pharmaceuticals

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving the nonmedical use of pharmaceuticals (prescription and over-the-counter medications and dietary supplements) for the Chicago metropolitan area, covering 2004-2011.  Nonmedical use includes patients who took a higher than prescribed or recommended dose of their own medication, patients who took a pharmaceutical prescribed for another person, malicious poisoning of the patient by another individual, and documented substance abuse involving pharmaceuticals.
Compound 527015: Acetylfentanyl

Chemical compound data from PubChem database. IUPAC Name: N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]acetamide. Molecular Formula: C21H26N2O. Molecular Weight: 322.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Lung toxicity and gene expression changes in response to whole-body inhalation exposure to cellulose nanocrystal in rats

Nanomaterials represent a new class of materials with numerous industrial applications. Considering the projected increase in the production and use of nanomaterials, a corresponding increase in occupational exposure to nanomaterials and their resulting adverse health effects should be anticipated among workers. There is substantial evidence in the literature, based on cell culture and animal studies, supporting the potential toxicity and detrimental health effects associated with exposure to nanomaterials. Intervention and/or prevention of adverse health effects associated with occupational exposure to toxic nanomaterials will be a major concern for health providers and regulatory and non-regulatory government agencies as the use of nanomaterials expand. A key element in the intervention and/or prevention of the adverse health effects associated with occupational exposure to toxic nanomaterials is a clear understanding of the molecular mechanisms underlying the pulmonary toxicity induced by nanomaterials.

Due to its physicochemical and mechanical properties, nanocellulose has found many applications in manufactured goods in the paper and food industry, cosmetics, biomedicine, and pharmaceuticals. There is potential for human exposure to nanocellulose or products that contain nanocellulose both during the production and use of the materials that contain nanocellulose. The objectives of the current study were to determine lung toxicity potential of crystalline nanocellulose (CNC) and the molecular mechanisms underlying the toxicity. A rat inhalation exposure model was employed to determine the lung toxicity potential of CNC. Global gene expression profile in the lung and bioinformatic analysis of the gene expression data were conducted to determine the molecular mechanisms underlying the CNC-induced lung toxicity.
Publications Using SAMHSA Data2013 CMHS Uniform Reporting System (URS) Table for Missouri

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Missouri for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273]

Background
          Etoricoxib is a highly selective COX-2 inhibitor which was evaluated for the treatment of rheumatoid arthritis (RA).
        
        
          Methods
          Double-blind, randomized, placebo and active comparator-controlled, 12-week study conducted at 67 sites in 28 countries. Eligible patients were chronic NSAID users who demonstrated a clinical worsening of arthritis upon withdrawal of prestudy NSAIDs. Patients received either placebo, etoricoxib 90 mg once daily, or naproxen 500 mg twice daily (2:2:1 allocation ratio). Primary efficacy measures included direct assessment of arthritis by counts of tender and swollen joints, and patient and investigator global assessments of disease activity. Key secondary measures included the Stanford Health Assessment Questionnaire, patient global assessment of pain, and the percentage of patients who achieved ACR20 responder criteria response (a composite of pain, inflammation, function, and global assessments). Tolerability was assessed by adverse events and routine laboratory evaluations.
        
        
          Results
          1171 patients were screened, 891 patients were randomized (N = 357 for placebo, N = 353 for etoricoxib, and N = 181 for naproxen), and 687 completed 12 weeks of treatment (N = 242 for placebo, N = 294 for etoricoxib, and N = 151 for naproxen). Compared with patients receiving placebo, patients receiving etoricoxib and naproxen showed significant improvements in all efficacy endpoints (p<0.05). Treatment responses were similar between the etoricoxib and naproxen groups for all endpoints. The percentage of patients who achieved ACR20 responder criteria response was 41% in the placebo group, 59% in the etoricoxib group, and 58% in the naproxen group. Etoricoxib and naproxen were both generally well tolerated.
        
        
          Conclusions
          In this study, etoricoxib 90 mg once daily was more effective than placebo and similar in efficacy to naproxen 500 mg twice daily for treating patients with RA over 12 weeks. Etoricoxib 90 mg was generally well tolerated in RA patients.
Antimicrobials and Allergic Disease: Identifying Novel Biomarkers and Mechanisms of Action

Occupational immune diseases are some of the most common illnesses that affect workers in the United States.  The Healthcare and Social Assistance Sector (HCSA) has one of the highest incidence of allergic disease compared to other industrial sectors. Individuals in this sector are frequently exposed to a variety of high-level cleaners and disinfectants along with antiseptics for the purposes of sterilization of surfaces, medical and surgical instruments, and reducing the incidence of nosocomial infections.  The range of specificity and effectiveness of these agents is very diverse based on the type of chemical used.  Commonly used antimicrobials include: alcohol, chlorine, iodine based agents; phenols; hydrogen peroxide; and quaternary ammonium compounds (QAC).   While the importance of these kinds of chemicals is understood, many of these agents are also known to directly contribute to allergic disease.  Antimicrobials including disinfectants and antiseptics are unique in that they have been identified to c
Compound 527691: Butanoic acid, 3-chloro, 2-propynyl ester

Chemical compound data from PubChem database. IUPAC Name: prop-2-ynyl 3-chlorobutanoate. Molecular Formula: C7H9ClO2. Molecular Weight: 160.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525841: N,N-Dimethyl-N'-hexyl-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N'-hexyl-N,N-dimethylpropanimidamide. Molecular Formula: C11H24N2. Molecular Weight: 184.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Ambulatory Surgery - Diagnosis, Procedure, and External Cause Codes

This dataset contains statewide counts for every diagnosis, procedure, and external cause of injury/morbidity code reported on the ambulatory surgery data.  Diagnosis codes are reported using ICD-9-CM or ICD-10-CM.  Procedure codes are reported using CPT-4.  External cause of injury/morbidity codes are reported using ICD-9-CM or ICD-10-CM.  ICD-10 replaced ICD-9, effective October 1, 2015.  Note: Physician-owned ambulatory surgery clinics do not report their data to HCAI and, therefore, are not included in the statewide frequencies.
Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation

Background
          Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis. It has been demonstrated that hepatic stellate cells undergo a process of activation during the development of liver fibrosis. During the activation process, hepatic stellate cells acquire myofibroblast-like phenotype featuring the expression of smooth muscle alpha actin. Interferons have been employed for the treatment of viral hepatitis. However, it is unclear what is the effect of interferons on the prevention and treatment of liver fibrosis. Moreover, it is not clear whether there are any differences among interferon alpha, interferon beta, and interferon gamma in the treatment of liver fibrosis. Therefore, our objective in current study is to investigate the effects of rat interferon-α, interferon-β, and interferon-γ on the proliferation and activation of rat hepatic stellate cells.
        
        
          Results
          Rat interferon-β and interferon-γ significantly inhibited rat hepatic stellate cell proliferation while rat interferon-α did not affect the cell proliferation under the same culture condition. Inhibition of cell proliferation was confirmed by both WST-1 cell proliferation assay and 5-bromo-2'-deoxy-uridine incorporation assay. Similar results were observed regarding interferons regulation of hepatic stellate cell activation. Both rat interferon-β and interferon-γ reduced smooth muscle α-actin abundance after 6 days treatment, but rat interferon-α did not alter smooth muscle α-actin level.
        
        
          Conclusions
          Our results indicate that rat interferon-α and interferon-β have different biological effects on rat hepatic stellate cells and suggest that there are different signaling events between interferon-α and interferon-β in hepatic stellate cells.
National Vaccine Injury Compensation Program (VICP) -Data & Statistics

<p>The VICP program publishes a summary PDF report with several data tables:</p>
<ul>
<li>
<p>Number of Petitions Filed by Adjudication Categories by Alleged Vaccine, including # of doses distributed (2006-2014)</p>
</li>
<li>
<p>Number of Petitions Filed, Compensated, and Dismissed by Alleged Vaccine (cumulative 1998 through 2016)</p>
</li>
<li>
<p>Number of Petitions Filed by year (1998-2017)</p>
</li>
<li>
<p>Number of Adjudications compensable, dismissed and total (FY1989 - FY2017)</p>
</li>
<li>
<p>Awards paid including amounts, attorneys fees, and total outlays (FY1989 - FY2016)</p>
</li>
</ul>