AndreaBozzo/ceres-open-data-index huggingface dataset:
Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios

Background
          The power of DNA microarrays derives from their ability to monitor the expression levels of many genes in parallel. One of the limitations of such powerful analytical tools is the inability to detect certain transcripts in the target sample because of artifacts caused by background noise or poor hybridization kinetics. The use of base-modified analogs of nucleoside triphosphates has been shown to increase complementary duplex stability in other applications, and here we attempted to enhance microarray hybridization signal across a wide range of sequences and expression levels by incorporating these nucleotides into labeled cRNA targets.
        
        
          Results
          RNA samples containing 2-aminoadenosine showed increases in signal intensity for a majority of the sequences. These results were similar, and additive, to those seen with an increase in the hybridization time. In contrast, 5-methyluridine and 5-methylcytidine decreased signal intensities. Hybridization specificity, as assessed by mismatch controls, was dependent on both target sequence and extent of substitution with the modified nucleotide. Concurrent incorporation of modified and unmodified ATP in a 1:1 ratio resulted in significantly greater numbers of above-threshold ratio calls across tissues, while preserving ratio integrity and reproducibility.
        
        
          Conclusions
          Incorporation of 2-aminoadenosine triphosphate into cRNA targets is a promising method for increasing signal detection in microarrays. Furthermore, this approach can be optimized to minimize impact on yield of amplified material and to increase the number of expression changes that can be detected.
CCWIS Design Requirements and Self Assessment Tool

This webinar described the CCWIS Design Requirements and preliminary work on the CCWIS Design Requirements and Self-Assessment Tool.  It included a description of the "conformance indicators" and a "scoring methodology" used to assess CCWIS design.  The webinar then described the Children's Bureau's process for conducting pilots and improving the tool, and it concluded with a discussion of the lessons learned from the pilots to date.

Descriptive Audio Version

Metadata-only record linking to the original dataset. Open original dataset below.
The NSDUH Report: State Estimates of Nonmedical Use of Prescription Pain Relievers

This short report uses 2010 to 2011 National Survey on Drug Use and Health (NSDUH) to assess past year nonmedical use of prescription-type drugs among persons aged 12 or older by State. Results are shown by age group and State by age group for 2009-2012 and 2010-2011.
TITLE IV-E PLAN AMENDMENT– Public Law (P.L.) 117-348 – The Trafficking Victims Prevention and Protection Reauthorization Act of 2022

This Program Instruction (PI) provides instruction on required actions for title IV-E agencies resulting from the enactment of the Trafficking Victims Prevention and Protection Reauthorization Act of 2022.

Metadata-only record linking to the original dataset. Open original dataset below.
Medicare Post-Acute Care Utilization - Home Health Agency by Geography, Provider and Service

The Medicare Post-Acute Care (PAC) Utilization - Home Health Agency (HHA) by Geography, Provider and Service supplemental dataset offers payment and utilization data for HHAs, organized by provider and Home Health Resource Group (HHRG) CMGs. It reflects the 153-group HHRG model for Calendar Years (CYs) 2014 - 2019 and the expanded 432-group model for CYs 2020 - 2023 under the Home Health Prospective Payment System (HH PPS). Low Utilization Payment Adjustment (LUPA) claims are excluded from all years, as they are not assigned an HHRG and are reimbursed per visit rather than through standardized payments.
DQS Infant mortality rates, by race and Hispanic origin of mother, state, and territory: United States and U.S. dependent areas (Archived)

This topic is no longer available in the NCHS Data Query System (DQS). Search, visualize, and download other estimates from over 120 health topics with DQS, available from: https://www.cdc.gov/nchs/dataquery/index.htm.
Data on on average annual infant mortality rates in the United States and U.S. dependent areas, by race and Hispanic origin of mother, state, and territory. Data are from Health, United States. SOURCE: National Center for Health Statistics, National Vital Statistics System, Linked Birth/Infant Death Data Set.
Percent of Adult Current Smokers by Sex and Race/Ethnicity, 1995-2010

This dataset is deprecated and will be removed by the end of the calendar year 2024. Updated on 8/18/2024

Adults are defined as 18 years of age and older. The CDC defines a "Current Smoker" as an adult who has smoked at least 100 cigarettes (5 packs) in their lifetime and currently smokes either "Every Day" or "Some Days." BRFSS data methodology changed in 2011; therefore, 2011 and after is not comparable to 2010 data and before.
Increasing the Impact of Community Organizations

This Child Welfare Information Gateway podcast is available on Apple Podcasts
  
  

, GooglePlay
  
  

, Spotify
  
  

, Stitcher
  
  

, SoundCloud
  
  

, and the Child Welfare Information Gateway
  
  

 website. Subscribe to receive new episodes as they are released.

Metadata-only record linking to the original dataset. Open original dataset below.
Trend Tables (Standard Errors and P Values) - 7.1 to 7.45

These detailed tables show standard errors for trends in totals and prevalence estimates of illicit drug use, risk and protective factors, substance initiation, substance dependence/abuse, and need/receipt of substance use treatment from the 2010 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens (including LSD, PCP, Ecstasy, Ketamine, DMT/AMT/Foxy, Salvia divinorum), inhalants, and the nonmedical use of prescription-type pain relievers (including OxyContin), tranquilizers, stimulants (Adderall), sedatives (GHB, Ambien), non-prescription cold medicine, alcohol, and tobacco products (including cigarettes, smokeless tobacco, cigars, pipes). Standard errors are provided for totals and estimates of lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area.
Compound 525457: 3-Propyl-2,4-dithiapentane

Chemical compound data from PubChem database. IUPAC Name: 1,1-bis(methylsulfanyl)butane. Molecular Formula: C6H14S2. Molecular Weight: 150.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528218: Naphthalene-2-carboxylic acid, 1-hydroxy, DTBS

Chemical compound data from PubChem database. IUPAC Name: 2,2-ditert-butylbenzo[h][1,3,2]benzodioxasilin-4-one. Molecular Formula: C19H24O3Si. Molecular Weight: 328.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E40060-T1: [Translated] NOZZLES FOR CASTING ALUMINUM KILLED STEELS.

Forming nozzles in two parts, the first as a body made of a refractory material, preferably zirconium oxide or magnesite, having a central axial cavity passing right through it, and the second as a body of a clacium-oxide based refractory material, having an appropriate passage for the liquid steel and located in said axial cavity.
Table 12. Alcohol Use in the Past Month among Persons Aged 12 to 20, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 12. Alcohol Use in the Past Month among Persons Aged 12 to 20, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Patent AT-E400351-T1: [Translated] DIVERED MEMBRANE ELEMENT AND MODULE

A filtering element has ultrafiltration or microfiltration hollow fiber membranes extending horizontally between a pair of opposed horizontally spaced, vertically extending headers. Side plates extending between the pair of vertically extending headers define a vertical flow channel through the element. Modules are created by placing the elements in place without obstructing the vertical flow channels. Each element may be released from the frame, however, and removed by sliding it in a direction substantially normal to its headers without disassembling the remainder of the module. The elements have associated releasable water tight fittings between the elements and a permeate collector, the releasable water tight fittings being releasable by removing an element from the frame. An aerator below the module has a plurality of air holes located to provide a line of air holes below each element or below a side plate between each pair of elements. In a preferred process, permeate flux is less than 50 L/m<2>/h and preferably less than 35 L/m<2>/h, aeration to scrub the membranes is provided during periods of time when permeation is periodically stopped and accumulated solids are removed by periodically emptying and refilling a tank containing the elements. A bubble point test is applied to each row of the module in turn, the presence of bubbles in a particular flow channel indicating which, if any, elements of a row are suitable.
Behavioral Risk Factor Surveillance Survey: 2020

The Behavioral Risk Factor Surveillance System (BRFSS) is an annual statewide telephone surveillance system designed by the Centers for Disease Control and Prevention (CDC). BRFSS monitors modifiable risk behaviors and other factors contributing to the leading causes of morbidity and mortality in the population. New York State's BRFSS sample represents the non-institutionalized adult household population, aged 18 years and older. Although the overall number of respondents in the BRFSS is more than sufficiently large for statistical inference purposes, subgroup analyses can lead to estimates that are unreliable. Interpreting and reporting weighted numbers that are based on a small, unweighted number of respondents can mislead the reader into believing that a given finding is much more precise than it actually is. The BRFSS follows a rule of not reporting or interpreting percentages based upon a denominator of fewer than 50 respondents (unweighted sample). Both a csv and sas data files are available. For more information see: http://www.health.ny.gov/statistics/brfss/
Long termin-vivostudies of a photo-oxidized bovine osteochondral transplant in sheep

Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been made to find the ideal graft for larger cartilage lesions. Different grafts, such as untreated or cryopreserved osteochondral transplants, have been used with variable success.
NSDUH 2018 Sample Experience Report

The goal of this report is to further document the 2018 NSDUH sample experiences, including a comparison of actual sample yields to state and quarter targets, a comparison of achieved and expected design effects (DEFFs) and relative standard errors, and documentation of any issue encountered during sample implementation. The 2018 sample design is thoroughly documented in the 2018 NSDUH sample design report (Center for Behavioral Health Statistics and Quality, 2019a).
Table 19. Illicit Drug Dependence or Abuse in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 19. Illicit Drug Dependence or Abuse in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs
Title IV-E Data

All title IV-E agencies (states, territories, and tribes) report financial information on a quarterly basis for the title IV-E Foster Care, Adoption Assistance, Guardianship Assistance, Prevention Services, and Kinship Navigator programs using Form CB-496. Form CB-496 quarterly reporting includes costs (expenditures and next-quarter estimates) and caseload data in various funding categories.

<b>Units of Response: </b>Program

<b>Type of Data: </b>Financial

<b>Tribal Data: </b>Yes

<b>Periodicity: </b>Annual

<b>Demographic Indicators: </b>Geographic Areas

<b>SORN: </b>Not Applicable

<b>Data Use Agreement: </b>No

<b>Data Use Agreement Location: </b>Unavailable

<b>Granularity: </b>Program;State

<b>Spatial: </b>United States

<b>Geocoding: </b>Unavailable
NCHS - Percent Distribution of Births to Unmarried Women by Age Group: United States

This dataset includes percent distribution of births to unmarried women by age group in the United States since 1970.

Methods for collecting information on marital status changed over the reporting period and have been documented in:

• Ventura SJ, Bachrach CA. Nonmarital childbearing in the United States, 1940–99. National vital statistics reports; vol 48 no 16. Hyattsville, Maryland: National Center for Health Statistics. 2000. Available from: http://www.cdc.gov/nchs/data/nvsr/nvsr48/nvs48_16.pdf.
• National Center for Health Statistics. User guide to the 2013 natality public use file. Hyattsville, Maryland: National Center for Health Statistics. 2014. Available from: http://www.cdc.gov/nchs/data_access/VitalStatsOnline.htm.
Molecular cloning of the rat proteinase-activated receptor 4 (PAR4)

Background
          The proteinase-activated receptor 4 (PAR4) is a G-protein-coupled receptor activated by proteases such as thrombin and trypsin. Although activation of PAR4 has been shown to modulate rat gastrointestinal motility, the rat PAR4 sequence was unknown until now. This study aimed to identify the rat PAR4 cDNA.
        
        
          Results
          The cDNA coding for the rat PAR4 homologue was cloned from the duodenum. Northern blots demonstrated a 3.0 kb transcript in the duodenum. Protein homology with mouse and human counterparts was 90% and 75% respectively. PAR4 is expressed predominantly in the esophagus, stomach, duodenum and the spleen. When expressed in COS cells, PAR4 is activated by trypsin (1 nM), thrombin (50 nM), mouse PAR4 specific peptide (500 μM) and a putative rat PAR4 specific activating peptide (100 μM), as measured by intracellular Ca2+-changes.
        
        
          Conclusions
          We have identified and characterized cDNA encoding the rat PAR4 homologue. PAR4 is expressed predominantly in the upper gastrointestinal tract. It is activated by trypsin, thrombin and its newly identified rat PAR4 specific activating peptide.
Patent AT-E401280-T1: [Translated] DEVICE AND METHOD FOR PROCESSING SEVERAL FABRIC MATERIALS SIMULTANEOUSLY

An apparatus for the concurrent converting of multiple web products includes at least a first unwind station and a second unwind station. The apparatus further includes a first web transformation station associated with a first web material unwound from the first unwind station, and a second web transformation station associated with the second web material unwound from the second unwind station. The first and second web transformation stations are disposed such that less than twice the width of the widest web material separates a portion of the first web material in the first web transformation station from a portion of the second web material in the second web transformation station. The method of the invention includes steps of unwinding web materials from rolls at each of the first and second unwind stations and transforming the respective web materials using the first and second web transformation stations.
Behavioral Health Barometer: Connecticut, 2013

This is a behavioral health report for the state of Conneticut. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment for the years 2008 to 2012.
Decision-making in Child Protective Services: A Study of Effectiveness, Phase I, 1997

The study will examine the criteria used by CPS workers to determine the level of the risk/severity for different types of abuse, to assess the likelihood of recurrence, and to decide to substantiate.  Criteria associated with placement during the investigation phase and postsubstantiation decisions regarding risk of imminent harm also will be examined.  Researchers will identify criteria most closely associated with each decision point and will develop models for each type of decision under study. These predictive models then can serve as a foundation for the development of decision protocols and recommendations regarding the enhancement of operation procedures.

Investigators: English, Diana
Serovar distribution of a DNA sequence involved in the antigenic relationship between

Background
          Horses infected with Leptospira present several clinical disorders, one of them being recurrent uveitis. A common endpoint of equine recurrent uveitis is blindness. Serovar pomona has often been incriminated, although others have also been reported. An antigenic relationship between this bacterium and equine cornea has been described in previous studies. A leptospiral DNA fragment that encodes cross-reacting epitopes was previously cloned and expressed in Escherichia coli.
        
        
          Results
          A region of that DNA fragment was subcloned and sequenced. Samples of leptospiral DNA from several sources were analysed by PCR with two primer pairs designed to amplify that region. Reference strains from serovars canicola, icterohaemorrhagiae, pomona, pyrogenes, wolffi, bataviae, sentot, hebdomadis and hardjo rendered products of the expected sizes with both pairs of primers. The specific DNA region was also amplified from isolates from Argentina belonging to serogroups Canicola and Pomona. Both L. biflexa serovar patoc and L. borgpetersenii serovar tarassovi rendered a negative result.
        
        
          Conclusions
          The DNA sequence related to the antigen mimicry with equine cornea was not exclusively found in serovar pomona as it was also detected in several strains of Leptospira belonging to different serovars. The results obtained with L. biflexa serovar patoc strain Patoc I and L. borgpetersenii serovar tarassovi strain Perepelicin suggest that this sequence is not present in these strains, which belong to different genomospecies than those which gave positive results. This is an interesting finding since L. biflexa comprises nonpathogenic strains and serovar tarassovi has not been associated clinically with equine uveitis.
Patent AT-E400007-T1: [Translated] CONTROL SYSTEM

There is described a method for controlling a system, for example a Diesel engine, that is subject to transient changes of target outputs. The target outputs specify outputs required from the system. "Steady state" information is used to give optimum inputs for the system when the target outputs are substantially constant. A model of the system is used to predict the outputs of the system in response to candidate new values for the inputs of the system. The method combines the steady state information with the predicted response of the system to determine inputs to the system which will cause the system outputs to match the target outputs as closely as possible. For each candidate (in one embodiment), the method calculates the difference between the steady state inputs and a candidate, and the difference between the target outputs and the predicted outputs that would result from the adoption of that candidate, to determine an optimum candidate which is then used to update the inputs to the system.
Compound 527565: 1,4-Cyclohexadiene, 6-bromo

Chemical compound data from PubChem database. IUPAC Name: 3-bromocyclohexa-1,4-diene. Molecular Formula: C6H7Br. Molecular Weight: 159.02. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529051: 1,2,4-Trithiolane, 3-methyl-5-(1-methylethyl), #1

Chemical compound data from PubChem database. IUPAC Name: 3-methyl-5-propan-2-yl-1,2,4-trithiolane. Molecular Formula: C6H12S3. Molecular Weight: 180.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530698: 2,3,4-Trifluorobenzoic acid, 2,6-dimethylnon-1-en-3-yn-5-yl ester

Chemical compound data from PubChem database. IUPAC Name: 2,6-dimethylnon-1-en-3-yn-5-yl 2,3,4-trifluorobenzoate. Molecular Formula: C18H19F3O2. Molecular Weight: 324.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Cumulative Influenza Vaccination Coverage, by Flu Season and Race/Ethnicity, Pregnant Women 18-49 years

Cumulative Influenza Vaccination Coverage, by Flu Season and Race/Ethnicity, Pregnant Women 18-49 years

• These monthly flu vaccination coverage estimates for pregnant women are based on electronic health record (EHR) data from the Vaccine Safety Datalink (VSD), a collaboration between CDC’s Immunization Safety Office and nine integrated health care organizations.§ This system has been used annually to estimate vaccination coverage among pregnant women. COVID-19 vaccination coverage for pregnant women is available here.

• Figure 3A. Monthly Cumulative Influenza Vaccination Coverage*, by Flu Season and Race/Ethnicity, Pregnant Women 18-49 years, United States, Data Source: Vaccine Safety Datalink

• Figure 3B. Cumulative Influenza Vaccination Coverage*, by Month, Flu Season, and Race/Ethnicity, Pregnant Women 18-49 years, United States, Data Source: Vaccine Safety Datalink

• For any month’s coverage estimate, the denominator is the number of women with a pregnancy during the current flu season (defined as August through March) beginning before or during the specified month. The numerator is the subset of the denominator who have received flu vaccination prior to, during, or after pregnancy. The denominator increases as more women are identified as pregnant or having been pregnant during the flu season. Cumulative vaccination coverage for one month may be lower than cumulative coverage for a previous month due to addition to the denominator of women who are less likely to have received vaccination.
Quality Assurance Reporting Requirements (QARR) Health Disparities 2013-2017

This dataset includes Medicaid Managed Care, Commercial HMO, and Commercial PPO performance data from the Quality Assurance Reporting Requirements (QARR) by member demographic characteristics. QARR is largely based on measures of quality developed and published by the National Committee for Quality Assurance (NCQA) Healthcare Effectiveness Data and Information Set (HEDIS®). Plans are required to submit quality performance data each year. Demographic information analyzed in this report includes members’ sex, age, race/ethnicity, Medicaid aid category, cash assistance status, behavioral health conditions including serious mental illness (SMI) and substance use disorder (SUD), payer status, and region of residence. Measuring the quality of care, and the ability to measure disparities in care is an important first step to a better understanding of the underlying factors that drive differences in care among certain populations within Medicaid Managed Care, Commercial HMO, and Commercial PPO.
These data are published annually for Medicaid Managed Care in the Health Care Disparities in New York State Report and on the NYSDOH web site: https://www.health.ny.gov/health_care/managed_care/reports/