AndreaBozzo/ceres-open-data-index huggingface dataset:
A reference database for tumor-related genes co-expressed with interleukin-8 using genome-scale

Background
          The EST database provides a rich resource for gene discovery and in silico expression analysis. We report a novel computational approach to identify co-expressed genes using EST database, and its application to IL-8.
        
        
          Results
          IL-8 is represented in 53 dbEST cDNA libraries. We calculated the frequency of occurrence of all the genes represented in these cDNA libraries, and ranked the candidates based on a Z-score. Additional analysis suggests that most IL-8 related genes are differentially expressed between non-tumor and tumor tissues. To focus on IL-8's function in tumor tissues, we further analyzed and ranked the genes in 16 IL-8 related tumor libraries.
        
        
          Conclusions
          This method generated a reference database for genes co-expressed with IL-8 and could facilitate further characterization of functional association among genes.
Compound 528946: 2-(3-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)-1,1-diphenylethyl acetate

Chemical compound data from PubChem database. IUPAC Name: 2-(2-methylbutan-2-yl)-6-nitrophenol. Molecular Formula: C11H15NO3. Molecular Weight: 209.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526884: 3,6,9,12-Tetraoxaheptadecan-1-OL

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-(2-pentoxyethoxy)ethoxy]ethoxy]ethanol. Molecular Formula: C13H28O5. Molecular Weight: 264.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400047-T1: [Translated] METHOD AND SYSTEM FOR AUTOMATICALLY PROVIDING LINGUISTIC FORMULATIONS WHICH ARE OUTSIDE A RECOGNITION DOMAIN OF AN AUTOMATIC LANGUAGE RECOGNITION SYSTEM

A method for automatically providing a hypothesis of a linguistic formulation that is uttered by users of a voice service based on an automatic speech recognition system and that is outside a recognition domain of the automatic speech recognition system. The method includes providing a constrained and an unconstrained speech recognition from an input speech signal, identifying a part of the constrained speech recognition outside the recognition domain, identifying a part of the unconstrained speech recognition corresponding to the identified part of the constrained speech recognition, and providing the linguistic formulation hypothesis based on the identified part of the unconstrained speech recognition.
Compound 529803: Benzamide, 4-hydroxy, 2-(1-methylethyl), N,6-dimethyl

Chemical compound data from PubChem database. IUPAC Name: 4-hydroxy-N,2-dimethyl-6-propan-2-ylbenzamide. Molecular Formula: C12H17NO2. Molecular Weight: 207.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400115-T1: [Translated] METHOD AND DEVICE FOR ALLOCATING A TRANSMISSION TIME SLOT IN A WIRELESS COMMUNICATIONS SYSTEM, AND SYSTEM THEREOF

An apparatus and method is provided for efficiently allocating a transmission period in a WLAN system. An access point (AP) transmits a PSMP message providing a downlink period and an uplink period provided to each station (STA), and at least one sub PSMP frame indicating a period of at least one of a downlink and an uplink for an STA requiring additional resource allocation. After exchanging data with the AP in the downlink and uplink periods provided by the PSMP frame, if there is a need for additional resource allocation, the STA receives the at least one sub PSMP frame and exchanges data with the AP in the period provided by the each sub PSMP frame.
Association of mesenchymal cells and immunoglobulins with differentiating epithelial cells

Background
          Mesenchymal-epithelial interactions play an important role in the physiology and pathology of epithelial tissues. Mesenchymal cells either associate with epithelium basement membrane [pericytes and perivascular monocyte-derived cells (MDC)] or reside within epithelium (MDC and T cells). Although intraepithelial mesenchymal cells were suggested to contribute to the epithelium physiology, their association with particular steps in differentiation of epithelial cells, interactions among themselves, and their fate remain unclear. We studied epitopes of mesenchymal cells and their products (immunoglobulins) in stratified epithelium of uterine ectocervix, which is one of the prototypes of complete cellular differentiation from stem into the aged cells.
        
        
          Results
          Perivascular CD14 primitive MDC associated with basal (stem) epithelial cells. Thy-1 pericytes of microvasculature secreted intercellular vesicles, which associated with Ki67 postmitotic epithelial cells expressing MHC class I. Intraepithelial T cells showed an association with veiled type MDC [dendritic cell (DC) precursors] among parabasal cells, and exhibited fragmentation after entering intermediate (mature) epithelial layers. Mature DC secreted CD68 and exhibited fragmentation after reaching mid intermediate layers. Binding of IgM was detected at the top of each layer: in the upper parabasal, upper intermediate, and most surface epithelial cells. IgG was confined to the entire superficial layer.
        
        
          Conclusions
          These data suggest that the phylogenetically and ontogenetically developed hierarchy of mesenchymal cells (MDC, pericytes, T cells) and immunoglobulins (IgM, IgG) accompanies differentiation of epithelial cells from immature into the mature and aged phenotype. Further studies of an involvement of mesenchymal cells in the regulation of tissue homeostasis may bring novel approaches to the prevention and therapy of tissue dysfunctions characterized by permanent tissue immaturity (muscular dystrophy) or accelerated aging (degenerative diseases).
Compound 526765: Ethyl linalyl acetate 1

Chemical compound data from PubChem database. IUPAC Name: (3-ethyl-7-methyloct-6-en-3-yl) acetate. Molecular Formula: C13H24O2. Molecular Weight: 212.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 530451: 4-Butylbenzoic acid, 4-hexadecyl ester

Chemical compound data from PubChem database. IUPAC Name: hexadecan-4-yl 4-butylbenzoate. Molecular Formula: C27H46O2. Molecular Weight: 402.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Information Memorandum (IM-19-03)

The purpose of this Information Memorandum (IM) is to demonstrate that family and youth voice are critical to a well-functioning child welfare system and to strongly encourage all public child welfare agencies, dependency courts, and Court Improvement Programs to work together to ensure that family and youth voice are central in child welfare program planning and improvement efforts.

Metadata-only record linking to the original dataset. Open original dataset below.
An Ecological Developmental Perspective on the Consequences of Child Maltreatment (1995-1996)

Cicchetti, Lynch, and Manly used the ecological-transactional model of child development to inform a three-part investigation of the links among child maltreatment, environmental conditions, and developmental outcomes.  In the first part of the research, the investigators examined the links between community violence, domestic violence, and poverty and the multiple dimensions of child maltreatment assessed by the investigators’ classification system.  In the second part of the research, the investigators examined the links between child maltreatment and various developmental outcomes.  Finally, in accordance with the ecological- transactional perspective, the investigators examined how child maltreatment interacts with other environmental conditions and child factors to shape the path of children’s development and their subsequent adaptation. Three hundred children between 7 and 12 years of age were recruited to participate in this study.  One hundred sixty-eight children (56% of the sample) had been identified as legally maltreated by the local department of social services and had their caregivers referred to study investigators by social service caseworkers.  A demographically similar comparison group of 132 non-maltreated children was recruited from the roll of families receiving Aid to Families with Dependent Children.  Both groups of children participated in week-long, 30 hour day camp sessions during the summers of 1995 and 1996.  Measures of the children’s interpersonal functioning, self-functioning, cognitive functioning, and symptoms of distress were assessed through self-, peer-, and counselor ratings.  Concurrently, primary caregivers were interviewed about community and home violence.  One-year longitudinal data were obtained for 95% of the child participants.  Follow-up measures were identical to those used during the first wave except that parent-report ratings were not obtained.  This dataset represents year one and two of a four year data collection effort. Dataset #110 contains the third and fourth year follow-up data.

Investigators: Dante Cicchetti, Ph.D. 
University of Rochester, Rochester, NY
Jody Todd Manly, Ph.D.
University of Rochester, Rochester, NY
Michael Lynch, Ph.D.
University of Rochester, Rochester, NY
Patent AT-E400388-T1: [Translated] COMBINED DEVICE FOR MATERIAL PROCESSING WITH A CUTTER AND A LASER

Laser-aided machine tool has a milling unit (3) working in conjunction with a laser beam. The assembly consists of a milling assembly (1), a spindle drive (2), laser (4), mirror (5), focusing lenses (6) and a workbench (7). The laser beam is coaxial with the milling axis and directed through a hollow shaft in the milling tool. The laser is directed at the tool/workpiece interface either simultaneously with or immediately following the tool action. The lens system (6) focuses the lens over a variable distance as required. The milling tool has gaps allowing escape of laser-generated combustion gases.
CCWIS Status

The following tables show the status of current child welfare information systems or projects in the states and tribes.

As of October 21, 2024 45 states, the District of Columbia, and Puerto Rico have declared as CCWIS.

The following is the key for the table columns:

CCWIS project and non-CCWIS project requirements can be found in the CCWIS regulation at 45 CFR § 1355.52—1355.55
  
  

 (PDF)

Metadata-only record linking to the original dataset. Open original dataset below.
Healthcare Associated Infections - National

The Healthcare-Associated Infections (HAI) measures - national data. These measures are developed by Centers for Disease Control and Prevention (CDC) and collected through the National Healthcare Safety Network (NHSN). They provide information on infections that occur while the patient is in the hospital. These infections can be related to devices, such as central lines and urinary catheters, or spread from patient to patient after contact with an infected person or surface. Many healthcare associated infections can be prevented when the hospitals use CDC-recommended infection control steps.
Patent AT-E40148-T1: [Translated] METHOD OF BRINGING SURFACES TOGETHER BY APPLYING A POLYURETHANE OR POLYETHERAMIDE JOINT, SURFACIAL MELTING THAT JOINT AND COOLING THEM.

1. Process for assembling, by jointing, two surfaces A and B, these surfaces being made of various materials such als glass, plastics, metal etc., characterized in that it consists in : a) applying to the surface A a seal in the shape of a strip of a thermoplastic material, based on a polymer chosen from the group comprising thermoplastic polyurethanes, polyetheramides or mixtures of both these thermoplastic polymers, b) placing the surface A so as to face the surface B, via its seal, and c) producing the assembly by melting the surface layer of the seal which is facing the surfaces B, placing in contact and cooling under a slight pressure.
Compound 525526: (3-Chloro-4-cyclohexylmethoxy-phenyl)-propionic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 3-[3-chloro-4-(cyclohexylmethoxy)phenyl]propanoate. Molecular Formula: C17H23ClO3. Molecular Weight: 310.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401083-T1: [Translated] METHOD USING ESTROGEN/PROGESTIN/ANTIPROGESTIN AND DEVICE FOR ORAL CONTRACEPTION AND REGULATION OF MENSTRATION

MENSES REGULATION AND, WHEN DESIRED, CONTRACEPTION IS ACHIEVED AT LOW DOSES OF ESTROGEN AND PROGESTIN, WHICH OTHERWISE WOULD CREATE EPISODES OF BREAKTHROUGH BLEEDING AND/OR WITHDRAWAL AMENORRHEA, BY PERIODICALLY INDUCING MENSES WITH AN ANTIPROGESTIN.
Bone morphogenetic protein-2 (BMP-2) and transforming growth factor-β1 (TGF-β1) alter connexin 43 phosphorylation in MC3T3-E1 Cells

Background
          Bone morphogenetic proteins (BMPs) and transforming growth factor-βs (TGF-βs) are important regulators of bone repair and regeneration. BMP-2 and TGF-β1 have been shown to inhibit gap junctional intercellular communication (GJIC) in MC3T3-E1 cells. Connexin 43 (Cx43) has been shown to mediate GJIC in osteoblasts and it is the predominant gap junctional protein expressed in these murine osteoblast-like cells. We examined the expression, phosphorylation, and subcellular localization of Cx43 after treatment with BMP-2 or TGF-β1 to investigate a possible mechanism for the inhibition of GJIC.
        
        
          Results
          Northern blot analysis revealed no detectable change in the expression of Cx43 mRNA. Western blot analysis demonstrated no significant change in the expression of total Cx43 protein. However, significantly higher ratios of unphosphorylated vs. phosphorylated forms of Cx43 were detected after BMP-2 or TGF-β1 treatment. Immunofluorescence and cell protein fractionation revealed no detectable change in the localization of Cx43 between the cytosol and plasma membrane.
        
        
          Conclusions
          BMP-2 and TGF-β1 do not alter expression of Cx43 at the mRNA or protein level. BMP-2 and TGF-β1 may inhibit GJIC by decreasing the phosphorylated form of Cx43 in MC3T3-E1 cells.
Compound 530510: 2-Chlorobenzoic acid, 2-adamantyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-adamantyl 2-chlorobenzoate. Molecular Formula: C17H19ClO2. Molecular Weight: 290.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Oregon: 2011-2012 NSDUH

This report presents Oregon\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Compound 529804: Benzamide, 4-hydroxy, 3-(1-methylethyl), N-methyl

Chemical compound data from PubChem database. IUPAC Name: 4-hydroxy-N-methyl-3-propan-2-ylbenzamide. Molecular Formula: C11H15NO2. Molecular Weight: 193.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
2005 NSDUH Detailed Tables

These are the 2005 national-level detailed tables for NSDUH.Illicit Drug Use Tables - 1.1 to 1.132Tobacco Product and Alcohol Use Tables - 2.1 to 2.114Risk and Protective Factors Tables - 3.1 to 3.69Incidence Tables - 4.1 to 4.16Dependence, Abuse, and Treatment Tables - 5.1 to 5.82Mental Health Tables - 6.1 to 6.67Miscellaneous Tables - 7.1 to 7.133Trend Tables - 8.1 to 8.37Sample Size and Population Estimates Tables - 9.1 to 9.22
Compound 526100: Tridecanoic acid, 12-methyl, trimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 12-methyltridecanoate. Molecular Formula: C17H36O2Si. Molecular Weight: 300.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400847-T1: [Translated] BIDIRECTIONAL METHOD-TO-METHOD BYTE STREAM PROTOCOL

A client system stores messages (710) and sends the messages to a server system. The messages are included in a request formatted (720) according to a protocol that can traverse a firewall. The server system also stores messages and sends the messages to the client system. The server system waits for a first request and a second request from the client system (740). If the first request has been received and a particular number of messages have accumulated at the server system, then the server system will send a response corresponding to the first request. If the second request is received (740), the server system will send the response (760) corresponding to the first request even if no messages have accumulated. The next time the client system sends a request, the request will include an indication of which messages the client system received from the server system in the last response.
Table 27. Had at Least One Major Depressive Episode in the Past Year among Persons Aged 18 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year major depressive episode among those aged 18 or older by State and substate regions.
MD iMAP: Maryland Vital Statistics - All Cause Mortality Rate

This is a MD iMAP hosted service layer. Find more information at http://imap.maryland.gov. The Division of Vital Records of the Maryland Department of Health and Mental Hygiene issues certified copies of birth -  death -  fetal death -  and marriage certificates for events that occur in Maryland. The Division also provides divorce verifications. The Division provides information on procedures to follow for registering an adoption -  legitimation -  or an adjudication of paternity. Maryland Age-Adjusted All-Cause Mortality Rate -  2010-2012. *Age-adjusted to the 2000 U.S. standard population. Rate per 100 - 000 Feature Service Layer Link: http://geodata.md.gov/imap/rest/services/Health/MD_VitalStatistics/FeatureServer/0 ADDITIONAL LICENSE TERMS: The Spatial Data and the information therein (collectively "the Data") is provided "as is" without warranty of any kind either expressed implied or statutory. The user assumes the entire risk as to quality and performance of the Data. No guarantee of accuracy is granted nor is any responsibility for reliance thereon assumed. In no event shall the State of Maryland be liable for direct indirect incidental consequential or special damages of any kind. The State of Maryland does not accept liability for any damages or misrepresentation caused by inaccuracies in the Data or as a result to changes to the Data nor is there responsibility assumed to maintain the Data in any manner or form. The Data can be freely distributed as long as the metadata entry is not modified or deleted. Any data derived from the Data must acknowledge the State of Maryland in the metadata.
NNDSS - TABLE 1CC. Rabies, Animal to Rabies, Human

NNDSS - TABLE 1CC. Rabies, Animal to Rabies, Human - 2021. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notice: Due to data processing issues at CDC, data for the following jurisdictions may be incomplete for week 7: Alaska, Arizona, California, Connecticut, Delaware, Florida, Hawaii, Louisiana, Maryland, Michigan, Missouri, North Dakota, New Hampshire, New York City, Oregon, Pennsylvania, and Rhode Island.

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
 Max: Maximum — Maximum case count during the previous 52 weeks.
  * Case counts for reporting years 2020 and 2021 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf. 
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
Treatment Episode Data Set (TEDS) 1999-2009 State Admissions to Substance Abuse Treatment Services

This report presents data from the Treatment Episode Data Set (TEDS) by census division and state for admissions in 2009, and trend data for 1999 to 2009. The report provides information on the demographic and substance abuse characteristics of people aged 12 and older admitted to treatment for abuse of alcohol and/or drugs in facilities that report to individual state administrative data systems.
Patent AT-E399778-T1: [Translated] GLUCOPYRANOSIDE, METHOD FOR ISOLATION THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF

A novel glucopyranoside, 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-beta-D-glucopyranoside of the formula (1) isolated from Pterocarpus marsupium and to a process for the isolation thereof is disclosed. The invention also relates to a pharmaceutical composition containing 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-beta-D-glucopyranoside and to method for the treatment of diabetes using said compound.