AndreaBozzo/ceres-open-data-index huggingface dataset:
Transjugular renal biopsy in high-risk patients: an American case series

Background
          In the United States, transjugular renal biopsies using the Quickcore™ side cut needle system have previously been described primarily for transjugular renal biopsy in patients with concurrent liver and kidney disease.
        
        
          Methods
          We describe transjugular renal biopsy with the Quickcore™ system in 9 patients with nephrotic syndrome and contraindications to percutaneous renal biopsy, who underwent biopsy between 23 October 1996 and 12 April 2001. The most common contraindication was oral anticoagulation with coumadin (40%). Other contraindications included horseshoe kidney, severe renal failure, and spontaneous coagulopathy. A 62 cm straight catheter and 60 cm side-cut Quickcore™ biopsy needle were used to obtain cortical tissue. Packing of the biopsy tract with Gelfoam™ was used for venographically identified capsular perforation.
        
        
          Results
          Ten procedures were performed on 9 patients with one requiring re-biopsy (5% of all renal biopsies performed at our institution). There were 9 transjugular renal biopsy and one combined liver-kidney biopsy. A mean of 4 ± 2 passes were made, with a mean of 3 ± 1 cores obtained per procedure. Histologic diagnosis was made in 90% of biopsies and in 100% of patients. Two patients developed transient hydronephrosis associated with gross hematuria; both required transfusion. Capsular perforation occurred in 90%. One patient died of bacterial sepsis, unrelated to the biopsy, several days after the procedure.
        
        
          Conclusions
          Transjugular renal biopsy appears to be efficacious in high-risk patients, for whom the percutaneous approach is contraindicated, including patients on oral anticoagulation. The transfusion rate in the present study was similar to other American reports using this technique.
New York State Nurse Aide Training Programs

Nurse Aide Training Programs provide comprehensive, quality education that equips students with the knowledge, skills, and compassionate attitude necessary to become competent and safe Certified Nursing Assistants capable of delivering high-standard patient care to a diverse population in a variety of healthcare settings.

Nurse Aide Training Programs offered in New York State may be approved by either the New York State Department of Health or the New York State Education Department. The Department of Health approves those programs provided by nursing homes free of charge to the student or trainee. All programs provided by entities under the jurisdiction of the State Education Department such as secondary or vocational schools, community colleges, proprietary schools, post-secondary schools, or any nurse aide training program that will charge the student or trainee tuition or fees must be approved by the State Education Department. 

The dataset identifies those nursing homes approved by the Department of Health to educate the student or trainee to become Certified Nursing Assistant. The Department of Health reviews and approves Nurse Aide Training Program applications continuously and updates the report monthly to include new and removed programs.
Phylogenetic relationships and taxonomic position of

Background
          Little is known about phytoplankton communities inhabiting low pH environments such as volcanic and geothermal sites or acidic waters. Only specialised organisms are able to tolerate such extreme conditions. There is, thus, low species diversity. We have characterised the previously isolated acid tolerant Chlorella-like microalgae Viridiella fridericiana and Chlorella protothecoides var. acidicola by microscopical and biomolecular methods in order to assess their phylogenetic relationships.
        
        
          Results
          Both isolates belong to the trebouxiophycean lineage of chlorophytes. 18S and ITS1 sequence data clearly confirm that Viridiella fridericiana constitutes a new genus apart from the morphologically similar and likewise acid tolerant microalga Chlorella saccharophila. Chlorella protothecoides var. acidicola on the other hand is not a variety of Chlorella protothecoides but falls within a heterogeneous cluster consisting of Nannochloris, "Chlorella" spec. Yanaqocha, and Koliella, and is most closely related to algae which were also isolated from extreme environments.
        
        
          Conclusions
          The distribution of acid tolerant strains in the 18S rRNA tree shows that acquisition of acid tolerance was unlikely a monophyletic event in green microalgae. We propose that different strains have independently adapted to extreme environments. Some of them have spread worldwide and were able to colonise other extreme habitats. Considering the problems of successfully isolating acid tolerant strains, acidic soils could represent an unsuspected source of biological diversity with high potential for biotechnological utilisations.
Patent AT-E401074-T1: [Translated] SYNERGISTIC ANTIBACTERIAL FORMULATION AND MANUFACTURING METHOD

A synergistic antibacterial formulation and a method of making the same is disclosed. The composition contains Cefixime Trihydrate + Cloxacillin Sodium + Lactobacillus sporogenes spores. The Cloxacillin sodium is in two forms in a sustained release and an immediate release form. A drug delivery system for providing the formulation is provided. <IMAGE>
Compound 525608: N,N-Dimethyl-N'-(4-nitrophenyl)-p-methoxybenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-methoxy-N,N-dimethyl-N'-(4-nitrophenyl)benzenecarboximidamide. Molecular Formula: C16H17N3O3. Molecular Weight: 299.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400882-T1: [Translated] ELECTRICAL DISCONNECTION DEVICE

The device has a flexible conductor fixed on one side to a movable contact (16.2) and fixed on another side to a part (11.1) of an electric circuit (11). The conductor comprises of a flexible tube (21), electrically conductive by surface, having low flexural rigidity to bend without being crushed and high torsional rigidity to take a form and a position reproducible in a closed state. An independent claim is also included for a gas insulated electrical substation.
AFCARS Report #16

This report provides preliminary estimaes of AFCARS data for FY 2008. Preliminary reports of AFCARS data include data received by September 30 for the report period ending March 31 and by March 31 for the report period ending September 30. This generally encompasses the required data submissions and submission of corrected data by States to avoid possible financial penalties.

Metadata-only record linking to the original dataset. Open original dataset below.
Rivaroxaban granule

Rivaroxaban Granule is a generic prescription medication manufactured by Lupin Pharmaceuticals, Inc., used as an anticoagulant to prevent blood clots. It comes as an oral suspension (1 mg/mL strength) for patients who may have difficulty swallowing pills. Approved under ANDA218195, it will be available starting September 29, 2025. This information was generated using AI and is provided for informational and research purposes only.
IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?

Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months of age, most female transgenics develop a lupus-like syndrome characterised by production of IgG anti-dsDNA, antihistone and antinucleosome autoantibodies. The autoantibodies are nephritogenic, with one-third of females developing a severe immune complex mediated glomerulonephritis. Analysis of these transgenics suggests that pathogenic autoantibodies arise via an antigen-driven T-cell-dependent mechanism with apoptotic keratinocytes acting as a potential source of autoantigen. The mechanism of autoantibody production in IFN-γ transgenics may be relevant to human lupus and is consistent with a central role for cutaneous T cells in the pathogenesis of systemic lupus erythematosus in man.
Patent AT-E401510-T1: [Translated] COUPLING MADE OF TWO ADJUSTABLE PLUG PARTS

Coupling of two adjustable plug-in parts (5,7) has first plug-in part with star shaped extension arm (6) and second plug-in part with corresponding adapted recesses (8a,8b,8c) for axially connecting the two drive sections of a drive for narrow side wall of a slab casting mould to adjust the breadth or tapering angle. The first and second plug-in part are also provided for connecting a connecting shaft of a spindle drive of power-split transmission or of joint head of hydraulic piston-cylinder drive. At the first plug-in part a radial swiveling two-piece ring (9) is formed and at the second plug-in part a circular groove (10) is formed. The two-piece ring in coupled position, two plug-in parts is rotationally fixed over form fit.
Compound 525203: Chloromethyl 3-chloro-octanoate

Chemical compound data from PubChem database. IUPAC Name: chloromethyl 3-chlorooctanoate. Molecular Formula: C9H16Cl2O2. Molecular Weight: 227.12. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Functional interaction between TRP4 and CFTR in mouse aorta endothelial cells

Background
          This study describes the functional interaction between the putative Ca2+ channel TRP4 and the cystic fibrosis transmembrane conductance regulator, CFTR, in mouse aorta endothelium (MAEC).
        
        
          Results
          MAEC cells express CFTR transcripts as shown by RT-PCR analysis. Application of a phosphorylating cocktail activated a Cl- current with characteristics similar to those of CFTR mediated currents in other cells types (slow activation by cAMP, absence of rectification, block by glibenclamide). The current is present in trp4 +/+ MAEC, but not in trp4 -/- cells, although the expression of CFTR seems unchanged in the trp4 deficient cells as judged from RT-PCR analysis.
        
        
          Conclusions
          It is concluded that TRP4 is necessary for CFTR activation in endothelium, possibly by providing a scaffold for the formation of functional CFTR channels.
Compound 525143: Decaethylene glycol, monoallyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl acetate. Molecular Formula: C25H48O12. Molecular Weight: 540.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Blockade of maitotoxin-induced oncotic cell death reveals zeiosis

Background
          Maitotoxin (MTX) initiates cell death by sequentially activating 1) Ca2+ influx via non-selective cation channels, 2) uptake of vital dyes via formation of large pores, and 3) release of lactate dehydrogenase, an indication of cell lysis. MTX also causes formation of membrane blebs, which dramatically dilate during the cytolysis phase. To determine the role of phospholipase C (PLC) in the cell death cascade, U73122, a specific inhibitor of PLC, and U73343, an inactive analog, were examined on MTX-induced responses in bovine aortic endothelial cells.
        
        
          Results
          Addition of either U73122 or U73343, prior to MTX, produced a concentration-dependent inhibition of the cell death cascade (IC50 ≈ 1.9 and 0.66 μM, respectively) suggesting that the effect of these agents was independent of PLC. Addition of U73343 shortly after MTX, prevented or attenuated the effects of the toxin, but addition at later times had little or no effect. Time-lapse videomicroscopy showed that U73343 dramatically altered the blebbing profile of MTX-treated cells. Specifically, U73343 blocked bleb dilation and converted the initial blebbing event into "zeiosis", a type of membrane blebbing commonly associated with apoptosis. Cells challenged with MTX and rescued by subsequent addition of U73343, showed enhanced caspase-3 activity 48 hr after the initial insult, consistent with activation of the apoptotic program.
        
        
          Conclusions
          Within minutes of MTX addition, endothelial cells die by oncosis. Rescue by addition of U73343 shortly after MTX showed that a small percentage of cells are destined to die by oncosis, but that a larger percentage survive; cells that survive the initial insult exhibit zeiosis and may ultimately die by apoptotic mechanisms.
NNDSS - Table 1B. Arboviral diseases, Jamestown Canyon virus disease to Powassan virus disease

NNDSS - TABLE 1B. Arboviral diseases, Jamestown Canyon virus disease to Powassan virus disease – 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non U.S. residents.

Notes:
•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.
Footnotes:
*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology

Background
          An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to considerable concern about the safety of the vaccine.
        
        
          Methods
          A matched case-control study using data derived form the United Kingdom General Practice Research Database. Children with a possible diagnosis of autism will be identified from their electronic health records. All diagnoses will be validated by a detailed review of hospital letters and by using information derived from a parental questionnaire. Ten controls per case will be selected from the database. Conditional logistic regression will be used to assess the association between MMR vaccination and autism. In addition case series analyses will be undertaken to estimate the relative incidence of onset of autism in defined time intervals after vaccination. The study is funded by the United Kingdom Medical Research Council.
        
        
          Discussion
          Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results.
Compound 530092: Flavanone, 5,4'-dihydroxy-7-methoxy, bis-TMS

Chemical compound data from PubChem database. IUPAC Name: 7-methoxy-5-trimethylsilyloxy-2-(4-trimethylsilyloxyphenyl)-2,3-dihydrochromen-4-one. Molecular Formula: C22H30O5Si2. Molecular Weight: 430.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
CDC STATE System Tobacco Legislation - Tax

1995-2024. Centers for Disease Control and Prevention (CDC). State Tobacco Activities Tracking and Evaluation (STATE) System. Legislation-Tax. The STATE System houses current and historical state-level legislative data on tobacco use prevention and control policies. Data are reported on a quarterly basis. Data include state taxes on combustible (cigarettes, cigars, little cigars, pipe tobacco, and roll-your-own tobacco) tobacco products, non-combustible (snus, moist snuff, dry snuff, chewing tobacco) tobacco products, and tax stamps.
2015 CMHS Uniform Reporting System (URS) Table for Iowa

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Iowa. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Program Instruction (PI-12-04)

This Program Instruction (PI) provides instruction on the availability of Fiscal Year (FY) 2012 Funds under the Community-Based Grants for the Prevention of Child Abuse and Neglect program created by Title II of the Child Abuse Prevention and Treatment Act (CAPTA) as amended by Public Law (P.L.) 111-320.

Metadata-only record linking to the original dataset. Open original dataset below.
Acetylcysteine

Acetylcysteine is a prescription drug used as an antidote for acetaminophen overdose and as a mucolytic to loosen mucus in the lungs. It comes as a solution for inhalation or oral use, in strengths like 10%, 20%, or 100 mg/mL, manufactured by Cameron Pharmaceuticals. This information was generated using AI and is provided for informational and research purposes only.
Compound 527738: Propanoic acid, 3-bromo, 4-methylpentyl ester

Chemical compound data from PubChem database. IUPAC Name: 4-methylpentyl 3-bromopropanoate. Molecular Formula: C9H17BrO2. Molecular Weight: 237.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400787-T1: [Translated] ARRANGEMENT FOR A WEAPON

An arrangement for a weapon including a countermass for reducing the pressure around the weapon. The countermass is enclosed in a countermass container that can be opened at both ends. The invention aims to bring about a symmetrical opening with favorable recoil in a better way than in previous constructions. This is achieved by the countermass including elements that can bind and retain the liquid symmetrically in a desired geometry over the cross section of the barrel and the cross section of any following expansion part.
CMS Program Statistics - Medicare Home Health Agency

The Medicare Home Health Agency tables provide use and payment data for home health agencies. The tables include use and expenditure data from home health Part A (Hospital Insurance) and Part B (Medical Insurance) claims.

For additional information on enrollment, providers, and Medicare use and payment, visit the CMS Program Statistics page.

 

Below is the list of tables:


	MDCR HHA 1.  Medicare Home Health Agencies:  Utilization and Program Payments for Original Medicare Beneficiaries, by Type of Entitlement, Yearly Trend
	MDCR HHA 2.  Medicare Home Health Agencies:  Utilization and Program Payments for Original Medicare Beneficiaries, by Demographic Characteristics and Medicare-Medicaid Enrollment Status
	MDCR HHA 3.  Medicare Home Health Agencies:  Utilization and Program Payments for Original Medicare Beneficiaries, by Area of Residence
	MDCR HHA 4.  Medicare Home Health Agencies:  Persons with Utilization and Total Service Visits for Original Medicare Beneficiaries, Type of Agency and Type of Service Visit
	MDCR HHA 5.  Medicare Home Health Agencies:  Persons with Utilization and Total Service Visits for Original Medicare Beneficiaries, by Type of Control and Type of Service Visit
	MDCR HHA 6.  Medicare Home Health Agencies:  Persons with Utilization, Total Service Visits, and Program Payments for Original Medicare Beneficiaries, by Number of Service Visits and Number of Episodes
Compound 525273: N,N-Dimethyl-N'-(3-nitrophenyl)ethanimidamide

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-(3-nitrophenyl)ethanimidamide. Molecular Formula: C10H13N3O2. Molecular Weight: 207.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525626: N,N-Dimethyl-N'-heptyl-benzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-heptyl-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H26N2. Molecular Weight: 246.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401611-T1: [Translated] METHOD AND DEVICE FOR MANUALLY RECORDING DIFFERENT EVENTS OR CONDITIONS

The method involves dividing the events/states into several classes; associating each event/state with a class; representing a two-dimensional object of any shape, preferably for each class, on a flat template (4) arranged with respect to the flat input field (2) of a data acquisition device so that by manual operation of an object a signal is generated that stores the entry position in a data set representing the entry field; and evaluating the data set after the manual entry and associating each event/state with a class. An Independent claim is also included for data acquisition device for implementing the method.
Compound 525425: 2-Thienylethylthiomethane

Chemical compound data from PubChem database. IUPAC Name: 2-(ethylsulfanylmethyl)thiophene. Molecular Formula: C7H10S2. Molecular Weight: 158.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.