AndreaBozzo/ceres-open-data-index huggingface dataset:
Publications Using SAMHSA DataEstimated totals and 95% confidence intervals (in thousands) for persons aged 12 or older, 12 to 17, 18 to 25, 26 or older, and 18 or older; also for persons 12 to 20 for two alcohol measures

This report presents estimates for measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Patent AT-E401010-T1: [Translated] SMOKABLE TOBACCO SUBSTITUTE FILLER HAVING A HIGHER FILLING VALUE AND METHOD FOR PRODUCING IT

Chemical patent from PubChem database. Patent Number: AT-E401010-T1. Title: Process for Preparing Therapeutic Agents. Filing Date: 2010-08-15. Inventors: Rodriguez, Juan, White, Jennifer. Abstract: A process for preparing therapeutic agents is described, involving multiple synthetic steps with optimized reaction conditions. The process enables la... IPC Classifications: C07K, A61K, G01N. This patent covers 29 claims related to 9 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
2014 CMHS Uniform Reporting System (URS) Table for Guam

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Guam. The URS territories reporting system is collected annually to support the Community Mental Health Services Block Grant program. Territories Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 526344: 2-Bromo-1,4,6,7,9-pentachloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 2-bromo-1,4,6,7,9-pentachlorodibenzo-p-dioxin. Molecular Formula: C12H2BrCl5O2. Molecular Weight: 435.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Archive: COVID-19 Vaccination Demographic Trends by Report Date, National

This data dictionary provides information about archived demographic trend data for people receiving COVID-19 vaccinations in the United States at the national level. Data represents all vaccine partners including jurisdictional partner clinics, retail pharmacies, long-term care facilities, dialysis centers, Federal Emergency Management Agency and Health Resources and Services Administration partner sites, and federal entity facilities. 

These data have been archived to provide historical demographic trend data for COVID-19 vaccine recipients prior to CDC converting the Vaccination Demographic Trends site to using data based on the date of vaccine administration. Previously, the Vaccination Demographic Trends site presented trend data by the date the vaccination was reported to CDC.
2012 Uniform Reporting System (URS) Tables for Massachusetts

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Cabergoline

Cabergoline is a prescription medication in 0.5 mg oral tablet form, classified as an ergot derivative and ergoline. It's used to treat conditions like hyperprolactinemia and Parkinson's disease. Manufactured by Amneal Pharmaceuticals NY LLC and SKG Pharma Inc. under ANDA218618, with NDC 83085-003, marketed since July 2024. This information was generated using AI and is provided for informational and research purposes only.
Clobazam

Clobazam is a prescription benzodiazepine medication available as oral tablets in 10 mg and 20 mg strengths. It is used to treat certain types of seizures and is classified as a controlled substance (Schedule CIV). Manufactured by MSN Laboratories Private Limited and Novadoz Pharmaceuticals LLC, it works by affecting brain chemicals to reduce seizure activity. This information was generated using AI and is provided for informational and research purposes only.
National Directory of Drug and Alcohol Abuse Treatment Facilities 2010

The National Directory of Drug and Alcohol Abuse Treatment Programs 2010 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 2009 National Survey of Substance Abuse Treatment Services (N-SSATS). The information about each facility that appears in this directory was provided by that facility in response to the 2009 N-SSATS. The Substance Abuse and Mental Health Services Administration (SAMHSA) conducts the N-SSATS annually.
P-Value Tables

State estimates for these years are no longer available due to methodological concerns with combining 2019 and 2020 data. We apologize for any inconvenience or confusion this may causeBecause of the COVID-19 pandemic, most respondents answered the survey via the web in Quarter 4 of 2020, even though all responses in Quarter 1 were from in-person interviews. It is known that people may respond to the survey differently while taking it online, thus introducing what is called a mode effect.When the state estimates were released, it was assumed that the mode effect was similar for different groups of people. However, later analyses have shown that this assumption should not be made. Because of these analyses, along with concerns about the rapid societal changes in 2020, it was determined that averages across the two years could be misleading.For more detail on this decision, see the 2019-2020state data page.
Compound 529043: Borane, isobutyl, dipropoxy

Chemical compound data from PubChem database. IUPAC Name: 2-methylpropyl(dipropoxy)borane. Molecular Formula: C10H23BO2. Molecular Weight: 186.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401350-T1: [Translated] DENTAL PREPARATIONS CONTAINING PEPTIDES THAT PROMOTE BONE GROWTH

Dental products such as toothpastes, mouthwash and dental floss are disclosed which products are enhanced by having dissolved, dispersed or coated thereon a compound which promotes bone growth. Preferred compounds are peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing an integrin binding motif such as RGD sequence and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. When the dental products are used repeatedly over time they enhance good dental health.
Results from the 2011 National Survey on Drug Use and Health: Mental Health Detailed Tables

This is the report pertaining to mental health from the 2011 National Survey on Drug Use and Health (NSDUH). The report presents national estimates of the prevalence of past year mental disorders and past year mental health service utilization for youths aged 12 to 17 and adults aged 18 or older. Among adults, estimates presented include rates and numbers of persons with any mental illness (AMI), serious mental illness (SMI), suicidal thoughts and behavior, major depressive episode (MDE), treatment for depression (among adults with MDE), and mental health service utilization. Estimates for youths include MDE, treatment for depression (among youths with MDE), and mental health service utilization. Measures related to the co-occurrence of mental disorders with substance use or with substance use disorders also are presented for both adults and youths. Results are provided for age group, gender, race/ethnicity, education level, employment status, poverty level, geographic area, insurance status. Comparisons are made between 2011 and 2002 to 2010.
Climate Shield Cutthroat Trout (50% Brook Trout), 2080 (Feature Layer)

This feature class represents the end-of-century (2070-2099) scenario for cutthroat trout, derived from the Climate Shield fish distribution models. These models provide stream-specific probabilistic predictions about the occurrence of juvenile bull trout and cutthroat trout in association with three different scenarios for climate change and brook trout invasions. These datasets indicate all potential cold-water habitats less than 11 degrees Celsius. The attribute fields CT_0BRK - CT_100BRK indicate the probabilities of cutthroat trout occurrence within a cold-water habitat based on the prevalence of brook trout at 0%, 25%, 50%, 75%, or 100% of the sites within a habitat. The probabilities were predicted using the Climate Shield native trout models developed from known species occurrence in greater than 500 cold-water streams. The stream centerlines were based on the National Hydrography Dataset (NHD) but were modified for purposes of modeling and cross-walking to other datasets.
Open tension free repair of inguinal hernias; the Lichtenstein technique

Background
          Recurrences have been a significant problem following hernia repair. Prosthetic materials have been increasingly used in hernia repair to prevent recurrences. Their use has been associated with several advantages, such as less postoperative pain, rapid recovery, low recurrence rates.
        
        
          Methods
          In this retrospective study, 540 tension-free inguinal hernia repairs were performed between August 1994 and December 1999 in 510 patients, using a polypropylene mesh (Lichtenstein technique). The main outcome measure was early and late morbidity and especially recurrence.
        
        
          Results
          Inguinal hernia was indirect in 55 % of cases (297 patients), direct in 30 % (162 patients) and of the pantaloon (mixed) type in 15 % (81 patients). Mean patient age was 53.7 years (range, 18 – 85). Follow-up was completed in 407 patients (80 %) by clinical examination or phone call. The median follow-up period was 3.8 years (range, 1 – 6 years). Seroma and hematoma formation requiring drainage was observed in 6 and 2 patients, respectively, while transient testicular swelling occurred in 5 patients. We have not observed acute infection or abscess formation related to the presence of the foreign body (mesh). In two patients, however, a delayed rejection of the mesh occurred 10 months and 4 years following surgery. There was one recurrence of the hernia (in one of these patients with late mesh rejection) (recurrence rate = 0.2 %). Postoperative neuralgia was observed in 5 patients (1 %).
        
        
          Conclusion
          Lichtenstein tension-free mesh inguinal hernia repair is a simple, safe, comfortable, effective method, with extremely low early and late morbidity and remarkably low recurrence rate and therefore it is our preferred method for hernia repair since 1994.
Medical Expenditure Panel Survey (MEPS) Insurance Component Complete Table Series PDFs

The Medical Expenditure Panel Survey Insurance Component (MEPS-IC) is an annual survey of private employers and State and local governments. The MEPS-IC produces national and State level estimates of employer-sponsored insurance, including offered plans, costs, employee eligibility, and number of enrollees. PDF files are available for complete sets of table series on employer-based health insurance at the national, state, and metropolitan area levels. The MEPS-IC is sponsored by the Agency for Healthcare Research and Quality and is fielded by the U.S. Census Bureau.
Long-term experimental evolution in

Background
          Experimental populations of Escherichia coli have evolved for 20,000 generations in a uniform environment. Their rate of improvement, as measured in competitions with the ancestor in that environment, has declined substantially over this period. This deceleration has been interpreted as the bacteria approaching a peak or plateau in a fitness landscape. Alternatively, this deceleration might be caused by non-transitive competitive interactions, in particular such that the measured advantage of later genotypes relative to earlier ones would be greater if they competed directly.
        
        
          Results
          To distinguish these two hypotheses, we performed a large set of competitions using one of the evolved lines. Twenty-one samples obtained at 1,000-generation intervals each competed against five genetically marked clones isolated at 5,000-generation intervals, with three-fold replication. The pattern of relative fitness values for these 315 pairwise competitions was compared with expectations under transitive and non-transitive models, the latter structured to produce the observed deceleration in fitness relative to the ancestor. In general, the relative fitness of later and earlier generations measured by direct competition agrees well with the fitness inferred from separately competing each against the ancestor. These data thus support the transitive model.
        
        
          Conclusion
          Non-transitive competitive interactions were not a major feature of evolution in this population. Instead, the pronounced deceleration in its rate of fitness improvement indicates that the population early on incorporated most of those mutations that provided the greatest gains, and subsequently relied on beneficial mutations that were fewer in number, smaller in effect, or both.
Patent AT-E399876-T1: [Translated] CHEMOENZYMATIC PROCESS FOR THE STEREOSELECTIVE PRODUCTION OF OPTICALLY ENRICHED PHENYLGLYCIDATE

The present invention relates to a novel and efficient chemoenzymatic process of preparation of optically active trans alkyl phenylglycidates. The invention particularly discloses a novel process for the chemoenzymatic synthesis of two enantiomers of trans alkyl phenylglycidate i.e. alkyl(2S,3R)-phenylglycidate and alkyl(2R,3S)-phenylglycidate of formulae 7 and 8 respectively
Compound 526307: 2,3,4,6,7,8-Hexabromodibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,3,4,6,7,8-hexabromodibenzofuran. Molecular Formula: C12H2Br6O. Molecular Weight: 641.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Development of real-time NASBA assays with molecular beacon detection to quantify mRNA coding for HHV-8 lytic and latent genes

Background
          Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the clinical stage of KS. To examine the expression of HHV-8 in PBMC, four HHV-8 mRNA specific NASBA assays were developed
        
        
          Methods
          We have developed four quantitative nucleic acid sequence-based amplification assays (NASBA-QT) specifically to detect mRNA coding for ORF 73 (latency-associated nuclear antigen, LANA), vGCR (a membrane receptor), vBcl-2 (a viral inhibitor of apoptosis) and vIL-6 (a viral growth factor). The NASBA technique amplifies nucleic acids without thermocycling and mRNA can be amplified in a dsDNA background. A molecular beacon is used during amplification to enable real-time detection of the product. The assays were tested on PBMC samples of two AIDS-KS patients from the Amsterdam Cohort.
        
        
          Results
          For all four assays, the limit of detection (LOD) of 50 molecules and the limit of quantification (LOQ) of 100 molecules were determined using in vitro transcribed RNA. The linear dynamic range was 50 to 107 molecules of HHV-8 mRNA. We found HHV-8 mRNA expression in 9 out of the 10 tested samples.
        
        
          Conclusion
          These real-time NASBA assays with beacon detection provide tools for further study of HHV-8 expression in patient material.
NSDUH 2021 Sample Design Report

This report describes the sample design for the 2021 National Survey on Drug Use and Health (NSDUH). It describes the target population and the five stages of sample selection, including the impact of coronavirus disease 2019 (COVID-19) pandemic. It also includes information on sample weighting and variance estimation procedures for the 2021 NSDUH.Chapter 1 introduces the report, describes the target population, provides a general overview of the 2021 NSDUH sample design, and summarizes the impact of the COVID-19 pandemic on the 2021 NSDUH. Chapter 2 summarizes the 2014 through 2022 coordinated design, while Chapter 3 discusses the first three stages of selection in greater detail. Chapter 4 describes the fourth and fifth stages of selection. Finally, Chapter 5 describes sample weighting and variance estimation procedures for 2021.The document is available as a PDF.
Delaware (DE)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Delaware for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Maine (ME)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Maine overall and for substate regions within Maine. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
2011 CMHS Uniform Reporting System (URS) Output Tables for Texas

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Congenital sucrase-isomaltase deficiency presenting with failure to thrive, hypercalcemia, and nephrocalcinosis

Background
          Disaccharide Intolerance Type I (Mendelian Interance in Man database: *222900) is a rare inborn error of metabolism resulting from mutation in sucrase-isomaltase (Enzyme Catalyzed 3.2.1.48). Usually, infants with SI deficiency come to attention because of chronic diarrhea and nutritional evidence of malabsorption.
        
        
          Case Presentation
          We describe an atypical presentation of this disorder in a 10-month-old infant. In addition to chronic diarrhea, the child displayed severe and chronic hypercalcemia, the evaluation of which was negative. An apparently coincidental right orbital hemangioma was detected. Following identification of the SI deficiency, an appropriately sucrose-restricted, but normal calcium diet regimen was instituted which led to cessation of diarrhea, substantial weight gain, and resolution of hypercalcemia.
        
        
          Conclusions
          This case illustrates that, similar to congenital lactase deficiency (Mendelian Interance in Man database: *223000, Alactasia, Hereditary Disaccharide Intolerance Type II), hypercalcemia may complicate neonatal Sucrase-Isomaltase deficiency. Hypercalcemia in the presence of chronic diarrhea should suggest disaccharide intolerance in young infants.
Compound 528179: 1,3-Cyclopentadiene, 2-nonyl

Chemical compound data from PubChem database. IUPAC Name: 2-nonylcyclopenta-1,3-diene. Molecular Formula: C14H24. Molecular Weight: 192.34. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Meta-analysis, Simpson's paradox, and the number needed to treat

Background
          There is debate concerning methods for calculating numbers needed to treat (NNT) from results of systematic reviews.
        
        
          Methods
          We investigate the susceptibility to bias for alternative methods for calculating NNTs through illustrative examples and mathematical theory.
        
        
          Results
          Two competing methods have been recommended: one method involves calculating the NNT from meta-analytical estimates, the other by treating the data as if it all arose from a single trial. The 'treat-as-one-trial' method was found to be susceptible to bias when there were imbalances between groups within one or more trials in the meta-analysis (Simpson's paradox). Calculation of NNTs from meta-analytical estimates is not prone to the same bias. The method of calculating the NNT from a meta-analysis depends on the treatment effect used. When relative measures of treatment effect are used the estimates of NNTs can be tailored to the level of baseline risk.
        
        
          Conclusions
          The treat-as-one-trial method of calculating numbers needed to treat should not be used as it is prone to bias. Analysts should always report the method they use to compute estimates to enable readers to judge whether it is appropriate.
Returning Citizen Child Support & Inmate Obligors 2007 - 2014

Data are provided by the Department of Human Resources (DHR) and University of Maryland. This dataset shows how many formerly incarcerated individuals in Maryland with child support payments are paying any portion on time. The dataset also shows how many incoming inmates to DPSCS have inmate obligors modified upon intake, as well as how many returning citizens have inmate obligors modified soon after release. The time period is month, calendar year, or fiscal year, as specified.
Compound 527230: Methyl 2-(8,8a-dimethyl-1,3,4,6,7,8-hexahydronaphthalen-2-ylidene)propanoate

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(8,8a-dimethyl-1,3,4,6,7,8-hexahydronaphthalen-2-ylidene)propanoate. Molecular Formula: C16H24O2. Molecular Weight: 248.36. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.