AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E400683-T1: [Translated] DEVICE FOR HYDRODYNAMIC ENGLISHING OF THE FIBERS OF A FIBER WEB

A device is known in which the bulky felt arriving on the top side of an endless belt for water felting is compacted between a felting drum and the belt and at the same time it is wetted by a first water curtain from a nozzle beam, whose water jets first pass through the endless belt and then the fiber web and finally the felting drum. Now, according to the invention, the unconsolidated felt is held against the bottom of an endless belt by means of induced suction and transported, and it is brought up tangentially to a needle felting drum, arranged beneath the endless belt. In this way, the handover of the fiber web from the endless belt to the needle felting drum is accomplished under the influence of gravity.
Compound 527784: Benzoic acid, 2-chloro, 2-propynyl ester

Chemical compound data from PubChem database. IUPAC Name: prop-2-ynyl 2-chlorobenzoate. Molecular Formula: C10H7ClO2. Molecular Weight: 194.61. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
IFNγ production in peripheral blood of early Lyme disease patients to hLFAα

Background
          It has been proposed that outer surface protein A (OspA) of Borrelia burgdorferi sensu stricto contains a T helper 1 (Th1) cell epitope that could play a role in an autoimmune response to hLFA1.
        
        
          Methods
          We used two peptides, hLFAαL (aa326-345) and Borrelia burgdorferi OspAB31 (aa164-183), as stimulating antigens to measure Th1 proinflammatory IFNγ cytokine production in peripheral blood of Lyme disease patients presenting with EM without history of arthritis, as well as in peripheral blood of healthy individuals.
        
        
          Results
          IFNγ responses to hLFA1 peptide were observed in 11 of 19 Lyme disease patients and in 3 of 15 healthy controls. In contrast, only 2 of 19 of the Lyme disease patients and none of the controls responded to the homologous OspAB31 peptide.
        
        
          Conclusions
          IFNγ was produced in response to stimulation with peptide hLFAαL (aa326-345) in peripheral blood of 58% of patients with early Lyme disease without signs of arthritis, as well as in peripheral blood of 20% of healthy individuals, but not in response to stimulation with the homologous OspAB31 (aa164-183) peptide (p < 0.05). Our results suggest that reactivity to the hLFA1 peptide in peripheral blood may be the result of T cell degeneracy.
National Child Abuse and Neglect Data System (NCANDS) Child File: Findings from the National Child Abuse and Neglect Data System (NCANDS) – File Contents and Definitions for the Data Tables (From Child Maltreatment 2017)

<p>The National Child Abuse and Neglect Data System (NCANDS) Child File data set consists of child-specific data of all reports of maltreatment to State child protective service agencies that received an investigation or assessment response. NCANDS is a Federally-sponsored national data collection effort created for the purpose of tracking the volume and nature of child maltreatment reporting each year within the United States. The Child File is the case-level component of the NCANDS. Child File data are collected annually through the voluntary participation of States. Participating States submit their data after going through a process in which the State's administrative system is mapped to the NCANDS data structure.  Data elements include the demographics of children and their perpetrators, types of maltreatment, investigation or assessment dispositions, risk factors, and services provided as a result of the investigation or assessment.</p>
Patent AT-E400437-T1: [Translated] SERVICE STATION FOR INKJET PRINT HEADS

A service station system for cleaning printheads, particularly inkjet printheads is provided. The service station includes a body having a seal attached thereto and at least one pressure operated sprayer attached to the body within an area demarcated by the seal. Each sprayer includes a bent cap, which enables spraying a cleaning agent at a predetermined spray angle. The sprayers are positioned so that substantially all of the nozzle plate will be wetted by the cleaning agent when the seal, the body and the nozzle plate are positioned to form an enclosed volume. The service station also includes a pressure release valve to keep the pressure within the enclosed volume at atmospheric level during spraying.
New Jersey (NJ)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for New Jersey overall and for substate regions within New Jersey. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Technical Bulletin #20 — Data Elements for Out-of-Home Care and Adoption and Guardianship Assistance Data Files

This technical bulletin gives reporting instructions and provides examples for the AFCARS 2020 out-of-home care and adoption and guardianship assistance data elements. The regulation for each element is shown in a blue box. Following the regulation language, CB provides explanatory text, examples, differences between AFCARS 1993 and AFCARS 2020, and data reporting standards. This Technical Bulletin was last revised on June 10, 2024.

Metadata-only record linking to the original dataset. Open original dataset below.
Hawaii 2016 Potential Areas for Addressing Service Gaps for Opioid Treatment

The purpose of the medication-assisted treatment (MAT) facility maps is to identify areas on a state-by-state basis that may be potentially underserved by existing treatment facilities. The maps are created with a methodology that seeks to include the highest potential need areas from individual counties so that county-level stakeholders are also informed. The maps are meant to be used as a tool for policy makers to determine potentially underserved areas—not as a definitive representation of these areas.
Compound 525632: N,N-Dimethyl-N'-hexyl-p-methoxybenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-hexyl-4-methoxy-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H26N2O. Molecular Weight: 262.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525599: N,N-Dimethyl-N'-(4-methoxyphenyl)-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-chloro-N'-(4-methoxyphenyl)-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H17ClN2O. Molecular Weight: 288.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Importance of lysosomal cysteine proteases in lung disease

The human lysosomal cysteine proteases are a family of 11 proteases whose members include cathepsins B, C, H, L, and S. The biology of these proteases was largely ignored for decades because of their lysosomal location and the belief that their function was limited to the terminal degradation of proteins. In the past 10 years, this view has changed as these proteases have been found to have specific functions within cells. This review highlights some of these functions, specifically their roles in matrix remodeling and in regulating the immune response, and their relationship to lung diseases.
Compound 525822: N-Phenyl-N'-(4-methylphenyl)formamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-methylphenyl)-N-phenylmethanimidamide. Molecular Formula: C14H14N2. Molecular Weight: 210.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529013: 1,4-Dimethyl-3,5-diethylbenzene

Chemical compound data from PubChem database. IUPAC Name: 1,3-diethyl-2,5-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527478: 2-Ethyl-3,5-dimethyl-5,6-dihydropyrazine

Chemical compound data from PubChem database. IUPAC Name: 5-ethyl-2,6-dimethyl-2,3-dihydropyrazine. Molecular Formula: C8H14N2. Molecular Weight: 138.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E40120-T1: [Translated] SUBSTITUTED 5-ACYLAMINO-1-PHENYLPYRAZOLS.

A 5-aminopyrazole of the formula   <IMAGE>    in which R1 represents alkoxycarbonyl, alkenyloxycarbonyl or alkinyloxycarbonyl, and R3, R4, R5, R6, and R7, which are identical or different, represent hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylsulphonyl, alkoxycarbonyl or a radical -(X)n-R8  wherein X represents oxygen, sulphur, sulphinyl or sulphyonyl, n represents 0 or 1 and R8 represents halogenoalkyl, with the proviso that at least one of the radicals R3, R4, R5, R6 or R7 represents a radical -(X)n-R8, and R1 does not represent cyano if R1 represents trifluoromethyl, These compounds are intermediates useful in the preparation of herbicidally active substituted 5-acylamino-1-phenylpyrazoles.
Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor

Background
          The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous PTEN was able to suppress their ability to grow anchorage-independently, and thus reverted one of the typical characteristics of tumor cells. As these findings indicated that PTEN might be involved in the regulation of anchorage-dependent cell growth, we analyzed this aspect of PTEN function in non-tumor cells with an anchorage-dependent phenotype.
        
        
          Results
          We found that in response to the disruption of cell-matrix interactions, expression of endogenous PTEN was transcriptionally activated, and elevated levels of PTEN protein and activity were present in the cells. These events correlated with decreased phosphorylation of focal adhesion kinase, and occurred even in the absence of p53, a tumor suppressor protein and recently established stimulator of PTEN transcription.
        
        
          Conclusions
          In view of PTEN's potent growth-inhibitory capacity, we conclude that its induction after cell-matrix disruptions contributes to the maintenance of the anchorage-dependent phenotype of normal cells.
NNDSS - TABLE 1HH. Syphilis, Congenital to Syphilis, Primary and Secondary

NNDSS - TABLE 1HH. Syphilis, Congenital to Syphilis, Primary and Secondary – 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:

•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.

Footnotes:

*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
NNDSS - TABLE 1U. Leptospirosis to Listeriosis, Probable

NNDSS - TABLE 1U. Leptospirosis to Listeriosis, Probable - 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:

•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.

Footnotes:

*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
Patent AT-E401710-T1: [Translated] METHOD AND DEVICE FOR EXECUTING A SECURE DATA TRANSFER IN A WIRELESS NETWORK

A method for executing secure data transfer between a communication device and an application server in a wireless network, in which a request requiring a secure transaction of data is sent from either the communication device or the server. An agreement proposal for the secure transaction is sent to the communication device, and if the agreement proposal is considered acceptable, the agreement proposal is sent to a security adapter. Details of the transaction are entered into a message and sent to a smart card in order to activate a signing application in the smart card. The details of the transaction are displayed on the communication device, and if the transaction is accepted, the signing application signs the data and sends it to the security adapter via messages, the signature is verified, and the data is sent to the server.
Patent AT-E400916-T1: [Translated] COOLING SYSTEM

The invention relates to a cooling system, with a cooler (1) taking up heat, for a permanently-energized synchronous motor, in particular, a motor for a locomotive. A first line (2) leads from the output of the cooler (1) to the input of a recirculation cooler (4), emitting heat to the environment. A second line (5) leads from the output of the recirculation cooler (4) to the input of the cooler (1). A first non-return valve (3), permitting flow towards the recirculation cooler (4), is arranged in the first line (2) and a second non-return valve (7), permitting flow towards the cooler (1), is arranged in the second line (5).
Program Instruction (PI-16-05)

The purpose of this Program Instruction (PI) is to set forth the eligibility requirements and grant application procedures for the basic, data and training CIP grants for FYs 2017 through 2021 and to provide guidance on the requirements for state courts to continuously assess and improve the handling of court proceedings related to child welfare and enhance collaboration with title IV-E/IV-B agencies and tribes.

ATTACHMENT B - SELF-ASSESSMENT TEMPLATE
(This attachment cannot be posted at this time. To request a copy of the document, please email Angelique Brown at angelique.brown@acf.hhs.gov).

ATTACHMENT D - STRATEGIC PLAN TEMPLATE
(This attachment cannot be posted at this time. To request a copy of the document, please email Angelique Brown at angelique.brown@acf.hhs.gov).

ATTACHMENT F - CHILDREN'S BUREAU REGIONAL OFFICE PROGRAM MANAGERS DIRECTORY

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 526952: Bis(3-thienyl) disulphide

Chemical compound data from PubChem database. IUPAC Name: 3-(thiophen-3-yldisulfanyl)thiophene. Molecular Formula: C8H6S4. Molecular Weight: 230.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Pro-domain removal in ASP-2 and the cleavage of the amyloid precursor are influenced by pH

Background
          One of the signatures of Alzheimer's disease is the accumulation of aggregated amyloid protein, Aβ, in the brain. Aβ arises from cleavage of the Amyloid Precursor protein by β and γ secretases, which present attractive candidates for therapeutic targeting. Two β-secretase candidates, ASP-1 and ASP-2, were identified as aspartic proteases, both of which cleave the amyloid precursor at the β-site. These are produced as immature transmembrane proteins containing a pro-segment.
        
        
          Results
          ASP-2 expressed in HEK293-cells cleaved the Swedish mutant amyloid precursor at different β-sites at different pHs in vitro. Recent reports show that furin cleaves the pro-peptide of ASP-2, whereas ASP-1 undergoes auto-catalysis. We show that purified recombinant ASP-2 cleaves its own pro-peptide at ph 5 but not pH  8.5 as seen by mass spectrometry, electrophoresis and N-terminal sequencing.
        
        
          Conclusion
          We suggest that ASP-2 processing as well as activity are influenced by pH, and hence the cellular localisation of the protein may have profound effects on the production of Aβ. These factors should be taken into consideration in the design of potential inhibitors for these enzymes.
NNDSS - Table II. Legionellosis to Malaria

NNDSS - Table II. Legionellosis to Malaria - 2018. In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed. The Table includes total number of cases reported in the United States, by region and by states or territory.

Note:

This table contains provisional cases of selected national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up.  Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html.
 
Footnotes:

C.N.M.I.: Commonwealth of Northern Mariana Islands. 
U: Unavailable. —: No reported cases. N: Not reportable. NA:  Not Available.  NN: Not Nationally Notifiable. NP: Nationally notifiable but not published. Cum: Cumulative year-to-date counts. Med: Median. Max: Maximum.
 
* Case counts for reporting years 2017 and 2018 are provisional and subject to change. Data for years 2013 through 2016 are finalized. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf.
Patent AT-E401265-T1: [Translated] VEHICLE FOR COLLECTING KITCHEN WASTE

The vehicle for collecting kitchen wastes has accumulation bin, which is hermetically sealed and has vacuum admitting pressure vessel, to which at least one suction lance is connected. The accumulation bin has a suction dome, which is connectable to a vacuum pump through a cutter. The accumulation bin has a heating water tank in travel direction of the vehicle, in which vacuum can be created. The vehicle has a chassis (1) on which accumulation bin (2) is mounted. The accumulation bin has a pouring device (6) for emptying rubbish containers through the opening (4) on which tiltable cover plate (8) is placed.