AndreaBozzo/ceres-open-data-index huggingface dataset:
CFSR Reviewer Responsibilities

JBS International, Inc.'s Child Welfare Reviews Project assists the Children's Bureau in recruiting and maintaining a national pool of child welfare professionals who meet the established minimum education and experience requirements to serve as Child and Family Services Review (CFSR) reviewers, quality assurance (QA) specialists, or note-taking specialists (collectively referred to as “agile staff”).

Participation in the CFSRs requires a significant commitment of time and effort. The following is a summary of the general responsibilities of agile staff participating in the CFSRs:

When participating in a CFSR, CFSR reviewers have the following responsibilities:

A CFSR reviewer may also be trained to perform as a note-taking specialist or QA specialist. These roles are generally reserved for experienced reviewers who have demonstrated a strong understanding of the OSRI and its application. The following is an overview of each position:

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 526492: 5-Amino-2'-fluoro-2-methylaminobenzophenone

Chemical compound data from PubChem database. IUPAC Name: [5-amino-2-(methylamino)phenyl]-(2-fluorophenyl)methanone. Molecular Formula: C14H13FN2O. Molecular Weight: 244.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
19th NCCAN Day One Opening Plenary

The 19th National Conference on Child Abuse and Neglect (NCCAN) was held from April 30 to May 2, 2014, in New Orleans, LA. Each day featured a plenary session on a specific topic. The opening plenary
  
  

 featured a presentation by Thomas L. Birch, J.D., and Deborah Daro, Ph.D., titled "Persuasive Claims: CAPTA's Myths, Memories, and Evidence," which recognizes the 40th anniversary of the adoption of the Child Abuse Prevention and Treatment Act (CAPTA). Other speakers include ACF Acting Assistant Secretary Mark Greenberg, J.D.; Melissa Lim Brodowski, Ph.D., M.S.W., M.P.H.; Angela White-Bazile, J.D.; Angelo McClain, Ph.D., L.I.C.S.W.

Metadata-only record linking to the original dataset. Open original dataset below.
Patent AT-E399804-T1: [Translated] GRADIENT COPOLYMERS SOLUBLE OR AT LEAST DISPERSIBLE IN WATER AND ORGANIC SOLVENTS

Gradient copolymer comprising at least 50 wt.% of a monomer (M1) whose homopolymer has a glass transition temperature (Tg) below 20degreesC and up to 50 wt.% of a monomer (M2) whose homopolymer has a Tg above 20degreesC, where at least one of the monomers is hydrophilic and makes up at least 5% of the total weight of the copolymer, comprises a monomer Mi such that the probability of finding Mi at any normalized position x in the polymer chain is nonzero.  Independent claims are also included for:  (1) production of a gradient copolymer by solution or bulk polymerization of a monomer mixture in the presence of a radical initiator and a chain transfer agent, where the monomer mixture comprises at least 50 wt.% M1 and up to 50 wt.% M2 and at least one of the monomers is hydrophilic and makes up at least 5% of the total weight of the mixture;  (2) preparing an aqueous solution of a gradient copolymer as above by dissolving the copolymer in a ketone solvent to form a 20-90% solution, neutralizing the solution (if necessary) by adding a molar solution of an acid or base, adding water or water/alcohol (99/1-50/50) with vigorous agitation to give a 1-80% solution, and evaporating the ketone;  (3) aqueous solutions prepared as above.
Compound 530403: Oxiranemethanol, 3-methyl-3-(4-methyl-3-pentenyl)-

Chemical compound data from PubChem database. IUPAC Name: [3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]methanol. Molecular Formula: C10H18O2. Molecular Weight: 170.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400738-T1: [Translated] WIND TURBINE WITH A HOLLOW SHAFT FOR THE ROTOR HUB AND GENERATOR

In a wind power installation with a (hollow) axis tube member and a hollow shaft mounted thereon for the rotor there is provided only a single bearing which also carries moments, between the axis tube member and the hollow shaft, whereby the parts of the machine which are to be fixed to the machine carrier and thus on the top of the pylon are of a markedly lower weight without the required orientation between the rotating and stationary parts of the electrical generator being adversely affected. In that arrangement the rotating part of the generator is radially aligned substantially with the bearing. The bearing to be used is in particular a twin-row inclined roller bearing with rows of rollers arranged at an angle of about 45° relative to each other.
Compound 529874: Pyrazine, 2-(2-pyrrylmethyl)-3,6-dimethyl

Chemical compound data from PubChem database. IUPAC Name: 2,5-dimethyl-3-(1H-pyrrol-2-ylmethyl)pyrazine. Molecular Formula: C11H13N3. Molecular Weight: 187.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Single-dose rofecoxib for acute postoperative pain in adults: a quantitative systematic review

Background
          Rofecoxib is a cyclo-oxygenase 2 selective inhibitor. This systematic review of rofecoxib in acute pain examined studies in adults of analgesic efficacy over six hours, the amount and quality of the evidence on extended duration of analgesia, and the quality and quantity of evidence on adverse events.
        
        
          Methods
          Cochrane Library (issue 4, 2001), Biological Abstracts (March 2002), MEDLINE (March 2002) and PubMed (March 2002) were searched using rofecoxib as a free text term. The area under the pain relief versus time curve was dichotomized using validated equations to derive the proportion of patients on rofecoxib 50 mg or placebo with at least 50% pain relief over six hours. This was used to calculate the number needed to treat for at least 50% pain relief over six hours for rofecoxib compared with placebo. Information on duration of analgesia and adverse events was also collected.
        
        
          Results
          Five included trials investigated 1,118 patients, of whom 211 received placebo and 464 received rofecoxib 50 mg. The NNT for rofecoxib 50 mg was 2.3 (95% confidence interval 2.0 to 2.6). The weighted mean remedication time was 1.9 hours for placebo (126 patients), 7.4 hours for ibuprofen 400 mg (97 patients) and 13.6 hours for rofecoxib 50 mg (322 patients).
        
        
          Conclusion
          Rofecoxib at 2–4 times the standard daily dose for chronic pain is an effective single dose oral analgesic in acute pain. Limitations in trial reporting constrain conclusions about longer duration of analgesia and adverse event profile.
Compound 526279: 1,3,7,9-Tetrabromo-2,8-dichloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 1,3,7,9-tetrabromo-2,8-dichlorodibenzo-p-dioxin. Molecular Formula: C12H2Br4Cl2O2. Molecular Weight: 568.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Implications of post-pneumonectomy compensatory lung growth in pulmonary physiology and disease

In a number of species, partial pneumonectomy initiates hormonally regulated compensatory growth of the remaining lung lobes that restores normal mass, structure and function. Compensation is qualitatively similar across species, but differs with gender, age and hormonal status. Although the biology of response is best characterized in rats, dogs have proven valuable in defining post-operative physiological adaptations. Most recently, mice were recognized to offer unique opportunities to explore the genetic basis of the response, as well as to evaluate associated detrimental effects of pathophysiological significance in animals exposed to carcinogens. The pneumonectomy model thus offers powerful insight concerning adaptive organ growth.
Compound 526692: 1,5-Anhydro-l-rhamnitol triacetate

Chemical compound data from PubChem database. IUPAC Name: (4,5-diacetyloxy-6-methyloxan-3-yl) acetate. Molecular Formula: C12H18O7. Molecular Weight: 274.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Georgia 2016 Potential Areas for Addressing Service Gaps for Opioid Treatment

The purpose of the medication-assisted treatment (MAT) facility maps is to identify areas on a state-by-state basis that may be potentially underserved by existing treatment facilities. The maps are created with a methodology that seeks to include the highest potential need areas from individual counties so that county-level stakeholders are also informed. The maps are meant to be used as a tool for policy makers to determine potentially underserved areas—not as a definitive representation of these areas.
Patent AT-E399872-T1: [Translated] EXPRESSION VECTORS CONTAINING THE PROMOTER OF THE IE2 GENE OF THE MOUSE CYTOMEGALOVIRUS

The invention relates to an expression vector comprising the promoter of the mCMV-IE2 gene, or a functional expression promoting fragment thereof, and/or an enhancer of the mCMV-IE2 gene, or a functional expression enhancing fragment thereof, wherein the expression vector does not contain any complete gene of the mCMV.
Patent AT-E399609-T1: [Translated] GAS SUPPLY DEVICE FOR A FLUSHING ELEMENT

Feed system for gas flushing of metallurgical vessels comprises a gas pipe (12) enclosed in a refractory pipe (10) of larger internal diameter than the internal diameter of the gas pipe. The outer pipe also encloses a cooling pipe (16) with perforations, through which cool air flows. An independent claim is included for walls and floors of metallurgical vessels fitted with the gas feed system.
Compound 529353: 4-Methyl-2-(propan-2-yl)pyridine

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-2-propan-2-ylpyridine. Molecular Formula: C9H13N. Molecular Weight: 135.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table 1I. Cryptosporidiosis to Cyclosporiasis

NNDSS - Table 1I. Cryptosporidiosis to Cyclosporiasis

NNDSS - Table 1I. Cryptosporidiosis to Cyclosporiasis - 2022. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notes:

•	These are weekly cases of selected infectious national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables available at https://www.cdc.gov/nndss/data-statistics/index.html. Cases reported by state health departments to CDC for weekly publication are subject to ongoing revision of information and delayed reporting. Therefore, numbers listed in later weeks may reflect changes made to these counts as additional information becomes available. Case counts in the tables are presented as published each week. See also Guide to Interpreting Provisional and Finalized NNDSS Data at https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
• Notices, errata, and other notes are available in the Notice To Data Users page at https://wonder.cdc.gov/nndss/NTR.html.
•	The list of national notifiable infectious diseases and conditions and their national surveillance case definitions are available at https://ndc.services.cdc.gov/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved by CSTE for national surveillance.

Footnotes:

*Case counts for reporting years 2021 and 2022 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
Developing a Solution for Nasal and Olfactory Transport of Nanomaterials

Nanotechnology is one of the most rapidly developing areas of the economy and involves the study and control of matter in the nanoscale. The nanoscale is the size range from 1 to 100 nm. Recently, some nanomaterials have demonstrated the ability to enter the brain through the olfactory pathway from the nose to the brain. ⁠This pathway can potentially enable inhaled nanomaterials to enter the brain. Inhalation exposures are technically difficult and expensive. Intranasal instillation is a potential screening tool for evaluating nose to brain transport. However, particles in aqueous media tend to agglomerate and agglomerated particles often act like larger particles in terms of surface area, toxicity, and size thresholds for transport pathways. For neuronal transport within the brain, the upper size limit is estimated to be approximately 100 nm. Therefore, nanomaterials must be adequately dispersed in the vehicle used for instillation in order to evaluate their potential for transport from the nose to the brain.

Because 100 nm is the upper size limit estimated for transport within the central nervous system, components of dispersion media may need to be different from dispersion media used to evaluate toxicity in other tissues. For example, albumin, a protein which is useful in dispersion media developed for the lung, can interact with nanomaterials and increase their size. In addition, neurons transport sodium out of the cell, suggesting that a dispersion medium to evaluate nose-to-brain transport should avoid high sodium concentrations. To overcome issues with the size of albumin and other proteins as well as the potential effects of sodium and phosphate, we hypothesized that free amino acids, a balanced electrolyte solution, and a mixture of phospholipids could produce a solution that both dispersed nanomaterials and was compatible with neuronal transport. This study describes and characterizes a solution for nasal and olfactory transport (SNOT) that can disperse nanomaterials and dyes with nanoscale dimensions, enabling intranasal instillation so that potential nose-to-brain transport can be evaluated.
4.11b : 2011. Percent

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing facilities offering special programs or groups for specific client types, by facility operation and primary focus of facility in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.
Monthly Cumulative Number and Percent of Adults 60 Years and Older Who Received at least one RSV Vaccination Doses by Jurisdiction, United States

Monthly Cumulative Number and Percent of Adults 60 Years and Older Who Received at least one RSV Vaccination Doses by Jurisdiction

• Estimated Respiratory Syncytial Virus (RSV) vaccination coverage for adults is assessed through U.S. jurisdictions’ Immunization Information Systems (IIS) data, submitted from jurisdictions to CDC monthly in aggregate by age group.

 • Starting in July 2023, the CDC recommended the RSV vaccine to protect against serious illness from RSV. (https://www.cdc.gov/respiratory-viruses/whats-new/rsv-update-2023-09-22.html)
2018-2020 NSDUH Substate Region Shapefile

Substate estimates for these years are no longer available due to methodological concerns with combining 2020 data with data from 2018 and 2019. We apologize for any inconvenience or confusion this may cause.Because of the COVID-19 pandemic, most respondents answered the survey via the web in Quarter 4 of 2020, even though all responses in Quarter 1 were from in-person interviews. It is known that people may respond to the survey differently while taking it online, thus introducing what is called a mode effect.When the state estimates were released, it was assumed that the mode effect was similar for different groups of people. However, later analyses have shown that this assumption should not be made. Because of these analyses, along with concerns about the rapid societal changes in 2020, it was determined that averages across the three years could be misleading.For more detail on this decision, see the 2018-2020substate data page.
Compound 529206: tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]amino)butanoate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 3-[[tert-butyl(dimethyl)silyl]amino]butanoate. Molecular Formula: C16H37NO2Si2. Molecular Weight: 331.64. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401825-T1: [Translated] APPARATUS AND METHOD FOR DIAGNOSTIC GAS ANALYSIS

A handheld, small but accurate and reliable device for diagnostic NO measurements using a NO sensor, where the parameters governing the taking of the sample are different from the parameters optimal for the accuracy of said NO sensor is described. By temporarily storing a portion of the exhaled air, and feeding this to the sensor at a flow rate adapted to the NO sensor, the accuracy and sensitivity of a system and/or a method involving NO sensors, can be increased.
Compound 527231: Porosadien-7-one

Chemical compound data from PubChem database. IUPAC Name: 1-(4,7a-dimethyl-1,5,6,7-tetrahydroinden-2-yl)-2-methylpropan-1-one. Molecular Formula: C15H22O. Molecular Weight: 218.33. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400525-T1: [Translated] DEVICE FOR GUIDING A YARN IN A WINDING MACHINE

A winder including a frame. The frame includes at least one spindle configured to support at least one package, the spindle rotating about a first axis approximately perpendicular to the diameter of the package so as to draw and wind at least one strand in the form of a package, and at least one positioning and guiding device configured to position and guide at least the strand on the rotating spindle. A keeper is configured to keep the strand in contact with the positioning and guiding device.
Patent AT-E400424-T1: [Translated] METHOD FOR PRODUCING GLASS OR CARBON FIBER REINFORCED PLASTIC

A mat is used in a method for the manufacture of glass fiber reinforced plastics or carbon fiber reinforced plastics as a layer for the absorption of excess resin expelled during the manufacturing process. The mat consists of thermally bonded plastic fibers, with at least one side of the mat having a solidified surface with a smaller pore size. Various methods are described for the manufacture of glass fiber reinforced plastics or carbon fiber reinforced plastics.
ED and HHS Letter to Chief State School Officers and Child Welfare Directors on Implementing the Fostering Connections Act

ED and HHS Letter to Chief State School Officers and Child Welfare Directors on Implementing the Fostering Connections Act
  
  

 (DOC) - Discusses supporting the well-being and educational outcomes of students in foster care through collaboration and cross-system coordination, as mandated by the Fostering Connections to Success  and Increasing Adoptions Act of 2008.

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Compound 530506: 3-Cyclopentylpropionic acid, dodec-9-ynyl

Chemical compound data from PubChem database. IUPAC Name: dodec-9-ynyl 3-cyclopentylpropanoate. Molecular Formula: C20H34O2. Molecular Weight: 306.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Guide to an AFCARS Assessment Review

This guide helps title IV-E agencies prepare for an Adoption and Foster Care Analysis and Reporting System (AFCARS) assessment review. It includes technical assistance and tools to conduct a self-assessment of a title IV-E agency’s data collection system and guidance for developing a system that supports AFCARS data collection.

The PDF is best viewed in Chrome or Firefox. If using Internet Explorer (IE), please right click the link, save the file, and view it locally.

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The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates

Background:
          Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination of cytosine. Four distinct families of UDGs have been identified, which show very limited sequence similarity to each other, although two of them have been shown to possess the same structural fold. The structural and evolutionary relationships between the rest of the UDGs remain uncertain.
        
        
          Results:
          Using sequence profile searches, multiple alignment analysis and protein structure comparisons, we show here that all known UDGs possess the same fold and must have evolved from a common ancestor. Although all UDGs catalyze essentially the same reaction, significant changes in the configuration of the catalytic residues were detected within their common fold, which probably results in differences in the biochemistry of these enzymes. The extreme sequence divergence of the UDGs, which is unusual for enzymes with the same principal activity, is probably due to the major role of the uracil-flipping caused by the conformational strain enacted by the enzyme on uracil-containing DNA, as compared with the catalytic action of individual polar residues. We predict two previously undetected families of UDGs and delineate a hypothetical scenario for their evolution.
        
        
          Conclusions:
          UDGs form a single protein superfamily with a distinct structural fold and a common evolutionary origin. Differences in the catalytic mechanism of the different families combined with the construction of the catalytic pocket have, however, resulted in extreme sequence divergence of these enzymes.