AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 529914: 3-Hexanone, 5-hydroxy-5-methyl

Chemical compound data from PubChem database. IUPAC Name: 5-hydroxy-5-methylhexan-3-one. Molecular Formula: C7H14O2. Molecular Weight: 130.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Statins as modulators of bone formation

The use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) to reduce serum cholesterol is well described. However, the recent finding that statins have direct effects on bone was unexpected. A number of epidemiological studies have recently been published that explore the effects of statins on bone mineral density and risk of fracture in humans. Statins may act by directly stimulating the expression of bone morphogenetic protein-2 and increasing osteoblast differentiation or, like nitrogen-containing bisphosphonates, may have effects on the mevalonate pathway that leads to inhibition of osteoclast activity and osteoblast apoptosis. In addition, the demonstration that statins can inhibit inflammation and encourage angiogenesis offers other possibilities for action.
Compound 530757: 2,6-Difluorobenzoic acid, phenyl ester

Chemical compound data from PubChem database. IUPAC Name: phenyl 2,6-difluorobenzoate. Molecular Formula: C13H8F2O2. Molecular Weight: 234.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Prevalence of Pneumoconiosis and its Relationship to Dust Exposure in a Cohort of U.S. Bituminous Coal Miners and ex-Miners

Information on radiographic evidence of coal workers’ pneumoconiosis (CWP) is presented for a group of 3,194 underground bituminous coal miners and ex-miners examined between 1985 and 1988. Prevalence of CWP was related to estimated cumulative dust exposure, age, and rank of coal. On the basis of these data, miners of medium to low rank coal, who work for 40 years at the current federal dust limit of 2 mg/m3, are predicted to have a 1.4% risk of having progressive massive fibrosis on retirement. Higher prevalences are predicted for less severe categories of CWP. Miners in high rank coal areas appear to be at greater risk than those mining medium and low rank coals. Ex-miners who said that they left mining for health-related reasons had higher levels of abnormality compared to current miners.
Patent AT-E400625-T1: [Translated] METHOD FOR PRODUCING BARSED ABRASIVES

A method of producing coated ultra-hard abrasive material, in particular coated diamond and CBN material. In a first step, an element capable of forming (singly or in combination) carbides, nitrides or borides to the surface(s) of the abrasive material is is applied using a hot coating process. At least one outer layer of a coating material selected from the group comprising transition metals, carbide, nitride, boride, oxide and carbonitride forming metals, metal carbides, metal nitrides, metal borides, metal oxides and metal carbonitrides, boronitrides and borocarbonitrides is applied over the inner layer by physical vapour deposition or chemical vapour deposition. Typically the inner layer elements come from groups IVa, Va, VIa, IIIb and IVb of the periodic table and include, for example, vanadium, molybdenum, tantalum, indium, zirconium, niobium, tungsten, aluminium, boron and silicon. The outer coating is preferably applied by reactive sputtering where a reactive gas is admitted to the sputtering chamber, resulting in the deposition of a compound of the reactive gas and the element being sputtered.
Treatment Episode Data Set (TEDS) 2002-2012: National Admissions to Substance Abuse Treatment Services

This report presents national-level data from the TEDS for admissions in 2012 and trend data for 2002 to 2012. The report provides information on the demographic and substance abuse characteristics of admissions to treatment aged 12 and older for abuse of alcohol and/or drugs in facilities that report to individual state administrative data systems.
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

Background
          Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated genes. In this paper we examine whether the signal from Toll-like receptors [TLRs] is sustained for as long as the ligand is present, and whether responses to different TLR agonists are additive.
        
        
          Results
          RAW264 macrophage cells were doubly-transfected with reporter genes in which the IL-12p40, ELAM or IL-6 promoter controls firefly luciferase, and the human IL-1β promoter drives renilla luciferase. The resultant stable lines provide robust assays of macrophage activation by TLR stimuli including LPS [TLR4], lipopeptide [TLR2], and bacterial DNA [TLR9], with each promoter demonstrating its own intrinsic characteristics. With each of the promoters, luciferase activity was induced over an 8 hr period, and thereafter reached a new steady state. Elevated expression required the continued presence of agonist. Sustained responses to different classes of agonist were perfectly additive. This pattern was confirmed by measuring inducible cytokine production in the same cells. While homodimerization of TLR4 mediates responses to LPS, TLR2 appears to require heterodimerization with another receptor such as TLR6. Transient expression of constitutively active forms of TLR4 or TLR2 plus TLR6 stimulated IL-12 promoter activity. The effect of LPS, a TLR4 agonist, was additive with that of TLR2/6 but not TLR4, whilst that of lipopeptide, a TLR2 agonist, was additive with TLR4 but not TLR2/6. Actions of bacterial DNA were additive with either TLR4 or TLR2/6.
        
        
          Conclusions
          These findings indicate that maximal activation by any one TLR pathway does not preclude further activation by another, suggesting that common downstream regulatory components are not limiting. Upon exposure to a TLR agonist, macrophages enter a state of sustained activation in which they continuously sense the presence of a microbial challenge.
Compound 526703: Perfluoro-pentan ethioic acid S-hexyl ester

Chemical compound data from PubChem database. IUPAC Name: S-hexyl 2,2,3,3,4,4,5,5,5-nonafluoropentanethioate. Molecular Formula: C11H13F9OS. Molecular Weight: 364.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Etonogestrel and ethinyl estradiol

Haloette is a prescription vaginal ring that releases etonogestrel and ethinyl estradiol to prevent pregnancy. Manufactured by Dr. Reddy's Laboratories Inc., it's inserted vaginally for 3 weeks, then removed for 1 week. This hormonal contraceptive works by inhibiting ovulation and altering cervical mucus. This information was generated using AI and is provided for informational and research purposes only.
Fragile Families and Child Wellbeing Study, Public Use, United States, 1998-2017

The Fragile Families and Child Wellbeing Study (FFCWS) follows a cohort of nearly 5,000 children born in large U.S. cities between 1998 and 2000 (roughly three-quarters of whom were born to unmarried parents). These parents and their children are referred to as "Fragile Families" to underscore that they are families and that they are at greater risk of breaking up and living in poverty than more traditional families.

The FFCWS was originally designed to address four main questions of great interest to researchers and policy makers: (1) What are the conditions and capabilities of unmarried parents, especially fathers?; (2) What is the nature of the relationships between unmarried parents?; (3) How do children born into these families fare?; and (4) How do policies and environmental conditions affect families and children?

The FFCWS consists of interviews with mothers, fathers, and/or primary caregivers at birth, and again when children are ages one, three, five, nine, and fifteen. The parent interviews collect information on attitudes, relationships, parenting behavior, demographic characteristics, health (mental and physical), economic and employment status, neighborhood characteristics, and program participation. At ages nine and fifteen, children were interviewed directly during home visits or on the telephone. The direct child interviews collect data on family relationships, home routines, schools, peers, and physical and mental health, as well as health behaviors.

<b>Units of Response: </b>Chlldren and families

<b>Type of Data: </b>Survey

<b>Tribal Data: </b>No

<b>COVID-19 Data: </b>No

<b>Periodicity: </b>Irregular

<b>SORN: </b>Not Applicable

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Unavailable

<b>Equity Indicators: </b>Disability;Ethnicity;Household Income;Household Size;Housing Status;Military;Race;Religion

<b>Granularity: </b>Household;Individual

<b>Spatial: </b>United States

<b>Geocoding: </b>Unavailable
Industries where health investment is growing

Everybody needs healthcare. Or at least they will need it at some point in their lives. And when there’s something that everyone needs, there’s a huge opportunity for investors.

Over $7.8 trillion is spent on healthcare globally. Nearly half of that total -- $3.5 trillion -- is spent in the U.S. With the healthcare sector growing significantly faster than the overall global economy, these numbers will almost certainly be much bigger by the end of the decade.

How can investors profit from this growth? Here’s what you need to know about investing in healthcare stocks.

Metadata-only record linking to the original dataset. Open original dataset below.
NNDSS - Table 1F. Brucellosis to Candida auris, clinical

NNDSS - Table 1F. Brucellosis to Candida auris, clinical - 2020. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents.

Notice: Data from California published in week 29 for years 2019 and 2020 were incomplete when originally published on July 24, 2020. On August 4, 2020, incomplete case counts were replaced with a "U" indicating case counts are not available for specified time period. 

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2019 and 2020 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data). 
§ Reporting jurisdictions were informed CDC could receive data for this condition in August 2019. Please note there will be a delay in reporting of case notifications for this condition to CDC.
Compound 530710: 5-Bromovaleric acid, tridec-2-ynyl ester

Chemical compound data from PubChem database. IUPAC Name: tridec-2-ynyl 5-bromopentanoate. Molecular Formula: C18H31BrO2. Molecular Weight: 359.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526558: 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-ol

Chemical compound data from PubChem database. IUPAC Name: 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Molecular Formula: C17H36O9. Molecular Weight: 384.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528231: bis-(2-Chloroethyl) tetrasulfide

Chemical compound data from PubChem database. IUPAC Name: 1-chloro-2-(2-chloroethyltetrasulfanyl)ethane. Molecular Formula: C4H8Cl2S4. Molecular Weight: 255.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401831-T1: [Translated] DIVISABLE MULTI-CATHETER ARRANGEMENT AND METHODS OF INSTALLATION THEREOF

A multiple lumen catheter assembly and methods for inserting the same are provided. The assembly includes a splittable membrane joining a first catheter and a second catheter for allowing the catheters to be at least partially longitudinally split from each other. Each catheter has at least one lumen extending longitudinally through the catheter. One method for inserting the assembly includes making an incision near the area to be catheterized, at least partially splitting the distal end regions of the catheters from each other by splitting apart the splittable membrane, and inserting the distal end regions of the catheters in a juxtaposed relation through the incision and into the area to be catheterized. In another method, the catheters are first tunnelled subcutaneously by pulling the distal end regions of the catheters in the assembly through a tunnel and outwardly from the tunnel near the area to be catheterized, leaving proximal end regions at least partially within the tunnel. An incision is made near the area to be catheterized, the distal end regions of the catheters are at least partially split from each other by splitting the splittable membrane, and the distal end regions of the catheters are inserted in a juxtaposed relation through the incision and into the area to be catheterized.
Compound 526255: 1,2,7,9-Tetrabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,7,9-tetrabromodibenzofuran. Molecular Formula: C12H4Br4O. Molecular Weight: 483.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400370-T1: [Translated] METHOD FOR SPRAYING PLASTIC LAYERS

A method and a device for applying a filler-containing plastics layer to even a shaped surface, in which a mixture containing a binder or a binder mixture and a filler is sprayed onto the surface, a free jet for application by spraying first being generated from a binder or binder mixture and the filler then being added to the free jet of the not yet polymerized binder or binder mixture. The method is particularly suitable for the spray application of heavy layers such as those used in conventional mass-spring systems.
Compound 530465: o-Toluic acid, 2-(1-adamantyl)ethyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-(1-adamantyl)ethyl 2-methylbenzoate. Molecular Formula: C20H26O2. Molecular Weight: 298.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Weather conditions and sudden sensorineural hearing loss

Background
          Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We investigated the seasonal distribution of ISSHL and evaluated the influence of meteorological parameters (such as temperature, humidity, and atmospheric pressure), their variation and covariation on the incidence of the disease.
        
        
          Methods
          A total of 82 cases of ISSHL, admitted to our department over a five-year period, were enrolled in the study. Seasonal distribution of the disease was investigated by dividing the year in four seasons. Meteorological data included daily values of 13 distinct parameters recorded at the meteorological station of the University of Ioannina during this period. A relationship between each meteorological variable and the incidence of ISSHL was investigated by applying (χ2) test on data from 13 contingency tables as well as by using logistic regression and t-test approaches. In addition, the influence of different weather types on the incidence of ISSHL was investigated using Cluster Analysis in order to create eight clusters (weather types) characteristic for the prefecture of Ioannina.
        
        
          Results
          The results of the study could not indicate any seasonal distribution of the disease. The incidence of ISSHL could not be significantly correlated either to any distinct meteorological parameter or to any specific weather type.
        
        
          Conclusions
          Meteorological conditions, such as those dominating in the Northwestern Greece, and/or their changes, have no proven effect on the incidence of ISSHL.
Birth-Foster Parent Mentoring Teams

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Metadata-only record linking to the original dataset. Open original dataset below.
Compound 526478: N-tert-butyl-2,2,3,3,4,4,4-heptafluoro-N-[3-[(5-oxo-7,8-dihydro-6H-naphthalen-1-yl)oxy]-2-trimethylsilyloxypropyl]butanamide

Chemical compound data from PubChem database. IUPAC Name: N-tert-butyl-2,2,3,3,4,4,4-heptafluoro-N-[3-[(5-oxo-7,8-dihydro-6H-naphthalen-1-yl)oxy]-2-trimethylsilyloxypropyl]butanamide. Molecular Formula: C24H32F7NO4Si. Molecular Weight: 559.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E39956-T1: [Translated] REINFORCEMENT CORD FOR REINFORCEMENT OF ELASTOMERIC PRODUCTS.

A reinforcing cord for use in radial tires, conveyor belts, hoses or driving belts, includes at least one strand of metal wires twisted along the longitudinal axis of the strand. Each metal wire has a substantially rectangular cross-section defining two opposite broad sides. The wires in the strand engage one another along their broad sides and preferably are wrapped around by a wrapping wire.
Compound 529082: Methyl 2-(3-phenoxyphenyl)propanoate

Chemical compound data from PubChem database. IUPAC Name: methyl 2-(3-phenoxyphenyl)propanoate. Molecular Formula: C16H16O3. Molecular Weight: 256.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hazardous Substances Data Bank (HSDB)

Hazardous Substances Data Bank (HSDB) was a toxicology database that focused on the toxicology of potentially hazardous chemicals. It provided information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, nanomaterials, and related areas. The information in HSDB has been assessed by a Scientific Review Panel.

This version of HSDB data includes a subset of HSDB for downloading, but is no longer updated. HSDB data has been incorporated into PubChem.
Compound 525861: N,N-Dimethyl-2-phenyl-N'-cyclohexyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N'-cyclohexyl-N,N-dimethyl-2-phenylethanimidamide. Molecular Formula: C16H24N2. Molecular Weight: 244.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Is It Injury or Neglect? Improving Our Knowledge to Better Protect Children

This webinar presenters discussed efforts to better define neglect in the context of accidental injury and described models of child death case reviews that will lead to improved understanding, reporting, and prevention strategies.

Presenters: Steven Wirtz, California Department of Public Health; Theresa Covington, National Center on Child Death Review; and Stephanie Biegler, Child Abuse Prevention Council of Sacramento, Inc.

View Webinar (WMV - 55 MB)

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525845: N,N-Dimethyl-N'-phenyl-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-phenylpropanimidamide. Molecular Formula: C11H16N2. Molecular Weight: 176.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Hawaii (HI)

This report presents Hawaii\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Hawaii for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
The NSDUH Report: Major Depressive Episode among Full-Time College Students and Other Young Adults, Aged 18 to 22

This issue of the National Survey on Drug Use and Health (NSDUH) Report presents combined 2008 to 2010 data to examine the prevalence of past year major depressive episode (MDE) among full-time college students and other young adults aged 18 to 22. Data on past year MDE, severity of impairment due to symptoms of depression, and receipt of speciality mental health treamtent are presented for full-time college students and other young adults, with some comparisons by gender and race/ethnicity.