AndreaBozzo/ceres-open-data-index huggingface dataset:
Cyclosporine

Cyclosporine is an ophthalmic emulsion medication at 0.05% strength, used as a prescription drug to treat certain eye conditions like dry eyes. Manufactured by Teva Pharmaceuticals, Inc., it's a generic version (ANDA203880) that works as a calcineurin inhibitor immunosuppressant. Available in single-dose vials, it started marketing on October 28, 2025. This information was generated using AI and is provided for informational and research purposes only.
Compound 529892: beta-Vetivene

Chemical compound data from PubChem database. IUPAC Name: 7-methylidene-4-propan-2-yltricyclo[6.2.1.02,6]undecane. Molecular Formula: C15H24. Molecular Weight: 204.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus

B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the newly discovered role of B-cell-activating factor (BAFF; also known as TALL-1, THANK, BlyS, and zTNF4) as a positive regulator of B-cell functions, such as B-cell activation and differentiation. Two members of the tumor necrosis factor(TNF)-receptor superfamily were recently identified as receptors for BAFF on B cells. The interaction between BAFF and its receptors may be important in the pathogenesis of lupus. Advances in our understanding of abnormalities in immune regulation in lupus might provide the opportunity to improve our current therapeutic approaches to this disorder.
Healthcare Payments Data (HPD): Fee-For-Service Drug Costs in the Commercial Market

The data set includes the top 25 list for costliest prescribed drugs, most frequently prescribed drugs and the prescribed drugs with the highest monthly median out-of-pocket costs. Each of these top 25 lists are given for commercial plans and are broken out by brand or generic category (i.e., Brand or Generic, Brand, and Generic). The includes National Drug Code (NDC), Drug Name, number of prescriptions, number of individuals, total costs, cost per prescription and monthly median out-of-pocket costs for each NDC in each top 25 list.
Strategic Health IT Advanced Research Projects (SHARP) Output Inventory

ONC established the SHARP program to support innovative research and to address well-documented problems that impede the adoption and use of health IT. The program covers four subject areas managed by four distinct project groups: health IT security (SHARPS), patient-centered cognitive support (SHARPc), health care application and network design (SMART), and secondary use of EHR information (SHARPn). This dataset provides the full inventory of project outputs from the SHARP program, ranging from presentations and manuscripts to APIs and software.
National Youth Survey US: Wave V (NYS-1980)

<p>Youth data for the fifth wave of the National Youth Survey<br />
are contained in this collection. The first wave of this survey was<br />
conducted in 1976, the second wave in 1977,<br />
the third wave in 1978, and the fourth wave in 1979. For this wave, youths in the United States were interviewed in<br />
early 1981 about events and behavior occurring in calendar year 1980.<br />
Data are available on the demographic and socioeconomic status of<br />
respondents, disruptive events in the home, neighborhood problems,<br />
youth aspirations and current successes, normlessness, labeling by<br />
parents, friends, and co-workers, perceived disapproval, attitudes<br />
toward deviance, exposure and commitment to delinquent peers, sex<br />
roles, interpersonal violence, attitudes toward sexual violence,<br />
pressure for substance abuse by peers, drug and alcohol use, and<br />
victimization.This study has 1 Data Set.</p>
State-level Comparisons of Mental Health Issues from the National Survey on Drug Use and Health (NSDUH) and the Behavioral Risk Factor Surveillance System (BRFSS)

This report compares state-level mental health prevalence estimates generated from the 2008 to 2014 National Surveys on Drug Use and Health (NSDUHs) with estimates of similar measures from the 2006 to 2013 Behavioral Risk Factor Surveillance System (BRFSS). It also describes the methodologies of these two surveys, such as survey mode and questionnaire design, and discusses how methodological differences may have contributed to differences in estimates.
Compound 526456: Ethyl perfluoropentanoate

Chemical compound data from PubChem database. IUPAC Name: ethyl 2,2,3,3,4,4,5,5,5-nonafluoropentanoate. Molecular Formula: C7H5F9O2. Molecular Weight: 292.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
A comparison of the illness beliefs of people with angina and their peers: a questionnaire study

Background
          What people believe about their illness may affect how they cope with it. It has been suggested that such beliefs stem from those commonly held within society . This study compared the beliefs held by people with angina, regarding causation and coping in angina, with the beliefs of their friends who do not suffer from angina.
        
        
          Methods
          Postal survey using the York Angina Beliefs Questionnaire (version 1), which elicits stress attributions and misconceived beliefs about causation and coping. This was administered to 164 people with angina and their non-cohabiting friends matched for age and sex. 132 people with angina and 94 friends completed the questionnaire.
        
        
          Results
          Peers are more likely than people with angina to believe that angina is caused by a worn out heart (p < 0.01), angina is a small heart attack (p = 0.02), and that it causes permanent damage to the heart (p < 0.001). Peers were also more likely to believe that people with angina should take life easy (p < 0.01) and avoid exercise (p = 0.04) and excitement (p < 0.01).
        
        
          Conclusions
          The beliefs of the peer group about causation and coping in angina run counter to professional advice. Over time this may contribute to a reduction in patient concordance with risk factor reduction, and may help to create cardiac invalids.
Arkansas: 2011-2012 NSDUH

This report presents Arkansas\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
Community Health Obesity and Diabetes Related Indicators: 2008 - 2012

This subset of the community health indicator report data will not be updated. A dataset containing all of the community health indicators is now available. To view the latest community health obesity and diabetes related indicators, see the featured content section. This Obesity and Diabetes Related Indicators dataset provides a subset of data (40 indicators) for the two topics: Obesity and Diabetes. The dataset includes percentage or rate for Cirrhosis/Diabetes and Obesity and Related Indicators, where available, for all counties, regions and state.   
New York State Community Health Indicator Reports (CHIRS) were developed in 2012, and annually updated to provide data for over 300 health indicators, organized by 15 health topic and data for all counties, regions and state are presented in table format with links to trend graphs and maps. 
Most recent county and state level data are provided. Multiple year combined data offers stable estimates for the burden and risk factors for these two health topics.
2010 CMHS Uniform Reporting System (URS) Output Tables for North Dakota

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
2010 CMHS Uniform Reporting System (URS) Output Tables for Federated States of Micronesia

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 525214: Chloromethyl 5-chloropentanoate

Chemical compound data from PubChem database. IUPAC Name: chloromethyl 5-chloropentanoate. Molecular Formula: C6H10Cl2O2. Molecular Weight: 185.05. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401687-T1: [Translated] FASTENING CLAMP FOR CABLE CHANNEL, ESPECIALLY FOR ELECTRICAL DEVICES

Chemical patent from PubChem database. Patent Number: AT-E401687-T1. Title: Novel Drug Delivery System. Filing Date: 2000-06-10. Inventors: Kim, Young-Soo, Taylor, Elizabeth. Abstract: The present invention discloses a drug delivery system designed to provide targeted and sustained release of therapeutic agents, improving patient com... IPC Classifications: C12N, C12P, A61K. This patent covers 44 claims related to 3 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.
Compound 525236: Propyl nonyl isophthalate

Chemical compound data from PubChem database. IUPAC Name: 3-O-nonyl 1-O-propyl benzene-1,3-dicarboxylate. Molecular Formula: C20H30O4. Molecular Weight: 334.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401559-T1: [Translated] SENSOR ELECTRONICS

A sensor device is capable of identifying any components of a mechanical force applied to a movable object. The sensor device includes a movable object including at least one magnetically encoded region having a magnetic field; a plurality of magnetic field detectors being placed around the at least one magnetically encoded region of the movable object at regular intervals; and a signal processing unit being connected to the plurality of magnetic field detectors. The plurality of magnetic field detectors are set up to convert changes in the magnetic field of the at least one magnetically encoded region caused by each component of the mechanical force applied to the movable object into corresponding electrical signals. The signal processing unit receives the corresponding electrical signals being representative for the respective components of the mechanical force applied to the movable object. The signal processing unit is programmed to identify the respective components of the mechanical force applied to the movable object on the basis of the corresponding electrical signals.
Compound 526447: 9-Methyl-6,7,8,9-tetrahydro-pyrido[2,1-b]quinazolin-11-one

Chemical compound data from PubChem database. IUPAC Name: 4-methyl-1,2,3,4-tetrahydropyrido[2,1-b]quinazolin-11-one. Molecular Formula: C13H14N2O. Molecular Weight: 214.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401076-T1: [Translated] QUINOLINE DERIVATIVES AS GLUCOCINASE LIGANDS

Compounds of formula (I), wherein one of R<SUP>1 </SUP>and R<SUP>2 </SUP>is selected from a group (IA), ring A is substituted pyridin-z-yl of thiazol-z-yl, the other substituents are as described in the description and their use in the treatment or prevention of a disease or medical conditions mediated through glucokinase.
Compound 528579: Glycine, N-[alpha-[(tert-butyldimethylsilyl)oxy]benzylidene]-, tert-butyldimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[[tert-butyl(dimethyl)silyl]oxy-phenylmethylidene]amino]acetate. Molecular Formula: C21H37NO3Si2. Molecular Weight: 407.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Drug Reference Vocabulary

The Drug Reference Vocabulary (DRV) is a classification system for all the substances collected by DAWN (drug-related emergency department visits and drug-related deaths investigated by partcipating medical examiners/coroners).  This Excel file includes brand, drug, and category names and codes for  illicit drugs, prescription and over-the-counter pharmaceuticals, inhalants and alcohol.  It is derived from the Multum Lexicon, © 2012 Lexi-Comp, Inc. and/or Cerner Multum, Inc. The classification was modified to meet DAWN\'s unique requirements.The Multum Licensing Agreement governing use of the Lexicon can be found on the SAMHSA site athttps://www.samhsa.gov/data/sites/default/files/MultumLicenseAgreement/….
MD COVID-19 - Vaccinations by Gender Distribution

Regarding all Vaccination Data
The date of Last Update is 4/21/2023. Additionally on 4/27/2023 several COVID-19 datasets were retired and no longer included in public COVID-19 data dissemination.

See this link for more information
https://imap.maryland.gov/pages/covid-data

<b>Summary</b>
The cumulative number of COVID-19 vaccinations reported by gender: Female; Male; Unknown.

<b>Description</b>
MD COVID-19 - Vaccinations by Gender Distribution data layer is a collection of COVID-19 vaccinations that have been reported each day into ImmuNet.

<b>Terms of Use</b>
The Spatial Data, and the information therein, (collectively the "Data") is provided "as is" without warranty of any kind, either expressed, implied, or statutory. The user assumes the entire risk as to quality and performance of the Data. No guarantee of accuracy is granted, nor is any responsibility for reliance thereon assumed. In no event shall the State of Maryland be liable for direct, indirect, incidental, consequential or special damages of any kind. The State of Maryland does not accept liability for any damages or misrepresentation caused by inaccuracies in the Data or as a result to changes to the Data, nor is there responsibility assumed to maintain the Data in any manner or form. 

The Data can be freely distributed as long as the metadata entry is not modified or deleted. Any data derived from the Data must acknowledge the State of Maryland in the metadata.
Compound 529354: 5-But-1-enyl-2-propylpyridine

Chemical compound data from PubChem database. IUPAC Name: 5-but-1-enyl-2-propylpyridine. Molecular Formula: C12H17N. Molecular Weight: 175.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400235-T1: [Translated] DEVICE AND SYSTEM FOR MITRAL VALVE THERAPY

An assembly and method for effecting the condition of a mitral valve annulus of a heart includes a guide wire configured to be fed into the coronary sinus of the heart, and a mitral valve annulus therapy device configured to be slidingly received on the guide wire and advanced into the coronary sinus of the heart on the guide wire. A guide tube may further be employed for guiding the device into the coronary sinus. An introducer which may be employed for pushing the device into or pulling device out of the heart has a mechanism for releasably locking to the device. This enables substitution of the device if needed. Also, the crossover point of the circumflex artery and coronary sinus may be determined and avoided when the device is deployed.
Compound 529331: 1H-Imidazole, 1-ethyl-4-methyl

Chemical compound data from PubChem database. IUPAC Name: 1-ethyl-4-methylimidazole. Molecular Formula: C6H10N2. Molecular Weight: 110.16. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Receipt of Services for Substance Use and Mental Health Issues among Adults: Results from the 2015 National Survey on Drug Use and Health

This report presents data from the 2015 National Survey on Drug Use and Health (NSDUH) for substance use treatment, and data from the 2002 through 2015 NSDUHs for mental health service use among adults aged 18 or older. Estimates for the receipt of substance use treatment (i.e., treatment for problems related to the use of alcohol or illicit drugs) are presented for young adults aged 18 to 25 and for adults aged 26 or older.  Estimates for mental health service use are shown for young adults, adults aged 26 to 49, and those aged 50 or older. Where trends for mental health service use are presented, the report focuses on long-term trends by comparing estimates from the 2015 NSDUH with comparable estimates from 2002 to 2014 (or from 2008 to 2014 for selected estimates). Statistically significant differences are noted between estimates in 2015 and those in prior years. Trends for substance use treatment and other related estimates are not reported because of methodological changes in 2015.
A transcriptional response to Wnt protein in human embryonic carcinoma cells

Background
          Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway.
        
        
          Results
          We have identified target genes of Wnt signaling using microarray technology and human embryonic carcinoma cells stimulated with active Wnt protein. The ~50 genes upregulated early after Wnt addition include the previously known Wnt targets Cyclin D1, MYC, ID2 and βTRCP. The newly identified targets, which include MSX1, MSX2, Nucleophosmin, Follistatin, TLE/Groucho, Ubc4/5E2, CBP/P300, Frizzled and REST/NRSF, have important implications for understanding the roles of Wnts in development and cancer. The protein synthesis inhibitor cycloheximide blocks induction by Wnt, consistent with a requirement for newly synthesized β-catenin protein prior to target gene activation. The promoters of nearly all the target genes we identified have putative TCF binding sites, and we show that the TCF binding site is required for induction of Follistatin. Several of the target genes have a cooperative response to a combination of Wnt and BMP.
        
        
          Conclusions
          Wnt signaling activates genes that promote stem cell fate and inhibit cellular differentiation and regulates a remarkable number of genes involved in its own signaling system.
Patent AT-E401626-T1: [Translated] MAGNETIC DATA VERIFICATION SYSTEM

A method of verifying the accuracy or authenticity of alphanumeric magnetic data on a document, wherein the configuration of a pictorial or graphic magnetic reference image in the document is made visible by bringing movable particulate magnetic material into proximity therewith such that the particulate magnetic material takes up a distribution corresponding to the magnetic field of the reference image; and the magnetic image configuration thus revealed is compared with the reference image to identify any significant disconformity suggesting past exposure of the document to a magnetic field capable of altering said magnetic data.
Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor

Background
          Modulation of the expression of retinoic acid receptors (RAR) α and γ in adult rat prostate by testosterone (T) suggests that RAR signaling events might mediate some of the androgen effects on prostate cells.
        
        
          Method
          In this study, we examined the interactions between T and retinoic acid (RA) in cell growth of human prostate carcinoma cells, LNCaP, and their relationship with the expression of RAR and epidermal growth factor receptor (EGF-R).
        
        
          Results
          Both T and RA, when administered alone, stimulated 3H-thymidine incorporation in LNCaP cells in a dose-dependent manner; the effect of each agent was reciprocally attenuated by the other agent. Testosterone treatment of LNCaP cells also resulted in dose dependent, biphasic increases in RAR α and γ mRNAs; increases paralleled that of 3H-thymidine incorporation and were attenuated by the presence of 100 nM RA. These results suggest a link between RAR signaling and the effect of T on LNCaP cell growth. Gel electrophoretic mobility shift assays revealed the presence of putative androgen responsive element (ARE) in the promoter region of RAR α gene, suggesting that a direct AR-DNA interaction might mediate the effects of T on RAR α gene. Furthermore, treatment of LNCaP cells with 20 nM T resulted in an increase in EGF-R. In contrast, EGF-R was suppressed by 100 nM RA that also suppressed the effect of T.
        
        
          Conclusions
          Current results demonstrate interactions between T and RA in the expression of RARs and cell growth in LNCaP cells. The presence of putative ARE in the promoter of the RAR α gene suggests that AR-DNA interaction might mediate the effects of T on RAR α gene. The opposite effects of T and RA on the expression of RAR and EGF-R suggest that signal events of these receptors might be involved in the interaction between T and RA in the control of LNCaP cell growth.
Patent AT-E40028-T1: [Translated] METHOD AND DEVICE FOR DETERMINING THE WORKING DEPTH OF SEED COILS OF SEED DRILLS.

1. Method for controlling the working depth of sowing coulters (3) of seed drills (2), wherein a probing device (6) probes the ground surface (4) and generates appropriate signals (S1 , S2 ,... Si ) which are evaluated in an evaluation circuit and are used for ascertaining the working depth (AT ), characterised in that a value (SM ) is ascertained from the signals (S1 , S2 ... Si ), which takes account of the clods (5) lying on the ground surface (4) and is characteristic of the ground profile, such value corresponding to a value which would be obtained when be obtained when probing an ideally smoothened ground surface, and in that the working depth (AT ) is determined in dependence upon this characteristic value.
Compound 525201: Methyl undecyl isophthalate

Chemical compound data from PubChem database. IUPAC Name: 1-O-methyl 3-O-undecyl benzene-1,3-dicarboxylate. Molecular Formula: C20H30O4. Molecular Weight: 334.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.