AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E39960-T1: [Translated] CONSOLE OF A SECURITY DEVICE AND SECURITY DEVICE WITH THIS CONSOLE.

1. A bracket (1 and 1') for safety devices comprising a vertical prop (2), perpendicular to whose base is welded a sleeve (3) accommodating a crossbeam called lower (4) which ends in a cap (5) and which can be immobilised in its movement by a pin (8), and at the upper part of the said prop are fixed : - on the one hand, by one (11) of its ends, a crossbeam (12) which extends on the side opposite to that where the lower crossbeam (4) has its cap (5), and whose other end (13) is supported by a brace (14) which in its turn rests on the base of the prop (2), and - on the other hand, on the side where the lower crossbeam (4) has its cap (5), a sleeve (24) whose front face has a cutout (18) for working in conjunction with a rod (19) anchored in the wall, this sleeve with a vertical axis being capable of accommodating a vertical bar (25, 48) ending at its upper part with a fixing means such as a plate having a cutout similar to that of the carrier (16) and which can be immobilised in its vertical movement by a horizontal pin (26) crossing a perforation (27) of the sleeve and one of the perforations of the vertical bar (25, 48), this bracket being characterised in that : - the sleeve (24) is formed by a carrier (16) whose back has the cutout (18), - the rod (19) is provided with a stop member (20) which is located between the arms (21, 22) of the carrier (16), - the perforation (27) of the sleeve (24) is positioned in such a way that, when, instead of suspension by a vertical bar, the bracket is directly suspended on a rod (19) passing through the cutout (18) of the back of the carrier (16), the placing of this pin (26) causes it to pass just under the stop member (20) in such a way that it then prevents the rod (19) from being detached from the cutout (18) and at the same time prevents the rotation of the said stop member (20), and - the arms (21, 22) of the carrier (16) each have at their base a cutout (29) in the form of a hook capable of covering a horizontal rail (30).
North Dakota (ND)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for North Dakota overall and for substate regions within North Dakota. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).
Compound 525838: N,N-Dimethyl-N'-cyclohexyl-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N'-cyclohexyl-N,N-dimethylpropanimidamide. Molecular Formula: C11H22N2. Molecular Weight: 182.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526870: 2-(2-(2-Isobutoxy-ethoxy)-ethoxy)-ethoxy)-ethyl TMS ether

Chemical compound data from PubChem database. IUPAC Name: trimethyl-[2-[2-[2-[2-(2-methylpropoxy)ethoxy]ethoxy]ethoxy]ethoxy]silane. Molecular Formula: C15H34O5Si. Molecular Weight: 322.51. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Institues of Health: Outreach

<p>This RSS Feed represents all Collaborative Research and Development (CRADA) opportunities available from the National Institutes of Health (NIH).The intent of Congress in establishing CRADAs was to promote national technological competitiveness and the rapid transfer of the fruits of innovation to the marketplace. CRADA research and development at the NIH should be directed to the development of biological and behavioral technology, products, and processes by transferring relevant knowledge acquired from NIH research efforts to state and local governments, universities, and the private sector.</p>
Compound 530446: 4-Butylbenzoic acid, 2-adamantyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-adamantyl 4-butylbenzoate. Molecular Formula: C21H28O2. Molecular Weight: 312.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 526453: 7-chloro-1-cyclopropyl-3-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one

Chemical compound data from PubChem database. IUPAC Name: 7-chloro-1-cyclopropyl-3-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one. Molecular Formula: C18H15ClN2O2. Molecular Weight: 326.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528371: Nornicotine, N-octanoyl

Chemical compound data from PubChem database. IUPAC Name: 1-(2-pyridin-3-ylpyrrolidin-1-yl)octan-1-one. Molecular Formula: C17H26N2O. Molecular Weight: 274.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529625: 2-Butyl-1,3-oxothiolane

Chemical compound data from PubChem database. IUPAC Name: 2-butyl-1,3-oxathiolane. Molecular Formula: C7H14OS. Molecular Weight: 146.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
SHIP Persons With A Usual Primary Care Provider 2011-2021

Persons With A Usual Primary Care Provider - This indicator shows the percentage of people who reported that they had one person they think of as their personal doctor or healthcare provider. <a href="https://health.maryland.gov/pophealth/Documents/SHIP/SHIP%20Lite%20Data%20Details/Persons%20with%20a%20Usual%20Primary%20Care%20Provider.pdf" > Link to Data Details </a>
Modelling developmental instability as the joint action of noise and stability: a Bayesian approach

Background
          Fluctuating asymmetry is assumed to measure individual and population level developmental stability. The latter may in turn show an association with stress, which can be observed through asymmetry-stress correlations. However, the recent literature does not support an ubiquitous relationship. Very little is known why some studies show relatively strong associations while others completely fail to find such a correlation. We propose a new Bayesian statistical framework to examine these associations
        
        
          Results
          We are considering developmental stability – i.e. the individual buffering capacity – as the biologically relevant trait and show that (i) little variation in developmental stability can explain observed variation in fluctuating asymmetry when the distribution of developmental stability is highly skewed, and (ii) that a previously developed tool (i.e. the hypothetical repeatability of fluctuating asymmetry) contains only limited information about variation in developmental stability, which stands in sharp contrast to the earlier established close association between the repeatability and developmental instability.
        
        
          Conclusion
          We provide tools to generate valuable information about the distribution of between-individual variation in developmental stability. A simple linear transformation of a previous model lead to completely different conclusions. Thus, theoretical modelling of asymmetry and stability appears to be very sensitive to the scale of inference. More research is urgently needed to get better insights in the developmental mechanisms of noise and stability. In spite of the fact that the model is likely to represent an oversimplification of reality, the accumulation of new insights could be incorporated in the Bayesian statistical approach to obtain more reliable estimation.
Venlafaxine

Venlafaxine Hydrochloride is a generic prescription medication used to treat major depressive disorder, generalized anxiety disorder, and other mood-related conditions. It works by balancing serotonin and norepinephrine in the brain. Available as oral tablets in strengths of 25mg, 37.5mg, 50mg, 75mg, and 100mg, manufactured by Heritage Pharmaceuticals Inc. This information was generated using AI and is provided for informational and research purposes only.
Lipidomics Profiling of Inflammatory and Specialized Pro-resolving Mediators at the Junction of Inflammation-Resolution Transition in Mouse Lungs Exposed to Multiwalled Carbon Nanotubes

Multi-walled carbon nanotubes (MWCNTs) are new nanomaterials made of graphene sheets that role into multi-layer, concentric tubes. MWCNTs are airborne and resistant to natural and biological degradation. The potential that inhalation of MWCNTS at the workplace overtime causes lung injury and disease is a considerable health concern for exposed workers. Exposure to certain MWCNTs induces prominent acute inflammation with lung injury in laboratory animals. How fibrogenic MWCNTs instigate inflammation and how the interplay between inflammation and resolution of inflammation influences fibrotic development from exposure to MWCNTs have not been well understood. This study addressed these knowledge gaps by using a quantitative lipidomics approach to systematically profile inflammatory lipid mediators and specialized pro-resolving lipid mediators, major mediators of inflammation and resolution, respectively, at the junction of transition from acute inflammation to fibrotic progression in mouse lungs exposed to fibrogenic MWCNTs.
Compound 528871: 3,4-Dimethyl-2-(propyldisulfanyl)thiophene

Chemical compound data from PubChem database. IUPAC Name: 3,4-dimethyl-2-(propyldisulfanyl)thiophene. Molecular Formula: C9H14S3. Molecular Weight: 218.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
The potential for research-based information in public health: Identifying unrecognised information needs

Objective
          To explore whether there is a potential for greater use of research-based information in public health practice in a local setting. Secondly, if research-based information is relevant, to explore the extent to which this generates questioning behaviour.
        
        
          Design
          Qualitative study using focus group discussions, observation and interviews.
        
        
          Setting
          Public health practices in Norway.
        
        
          Participants
          52 public health practitioners.
        
        
          Results
          In general, the public health practitioners had a positive attitude towards research-based information, but believed that they had few cases requiring this type of information. They did say, however, that there might be a potential for greater use. During five focus groups and six observation days we identified 28 questions/cases where it would have been appropriate to seek out research evidence according to our definition. Three of the public health practitioners identified three of these 28 cases as questions for which research-based information could have been relevant. This gap is interpreted as representing unrecognised information needs.
        
        
          Conclusions
          There is an unrealised potential in public health practice for more frequent and extensive use of research-based information. The practitioners did not appear to reflect on the need for scientific information when faced with new cases and few questions of this type were generated.
Low prevalence of liver-kidney microsomal autoantibodies of type 1 (LKM

Background
          Hepatitis C is a serious problem on the Greek island of Crete, where a high prevalence of antibodies against hepatitis C (anti-HCV) has recently been reported. This article reports the findings of a study carried out in Crete, which investigated the prevalence of serum autoantibodies in patients with chronic hepatitis C.
        
        
          Patients and Methods
          One hundred and forty two patients (59 men and 83 women), who were found anti-HCV seropositive in two hospitals and two Primary Health Care Centres in Crete, were eligible. Sixty healthy blood donors (46 men, 14 women), which were negative to anti-HCV, were used as the control group. They were randomly selected from those attending Rethymnon Hospital. Autoantibodies were identified using the indirect immunofluorescence (IFL) technique on human epithelial cells from larynx cancer (HEp-2 cells), rat liver-kidney-stomach substrate (CT3) and Chrithidia Luciliae (CL).
        
        
          Results
          Serum autoantibodies were detected in 104 HCV patients, yielding an overall prevalence of 73.2%. The most frequent autoantibodies were antinuclear antibodies (ANA), positive in 72 patients (50.7%). Anti-smooth muscle antibodies (ASMA) were detected in 33 patients (23.2%). Only one patient was positive for LKM1 autoantibodies. No autoantibodies were found in 38 patients (26.7%). Autoantibodies were also found in 5 out of the 60 examined healthy blood donors (8.3%).
        
        
          Conclusions
          Autoantibodies, mainly ANA and ASMA are very common in HCV seropositive patients from Crete. By contrast LKM1 autoantibodies are exceptionally rare in these patients.
Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes

Background
          Thioredoxin reductase (TR) is a redox active protein involved in many cellular processes as part of the thioredoxin system. Presently there are three recognised forms of mammalian thioredoxin reductase designated as TR1, TR3 and TGR, that represent the cytosolic, mitochondrial and novel forms respectively. In this study we elucidated the genomic organisation of the mouse (Txnrd1) and human thioredoxin reductase 1 genes (TXNRD1) through library screening, restriction mapping and database mining.
        
        
          Results
          The human TXNRD1 gene spans 100 kb of genomic DNA organised into 16 exons and the mouse Txnrd1 gene has a similar exon/intron arrangement. We also analysed the alternative splicing patterns displayed by the mouse and human thioredoxin reductase 1 genes and mapped the different mRNA isoforms with respect to genomic organisation. These isoforms differ at the 5' end and encode putative proteins of different molecular mass. Genomic DNA sequences upstream of mouse exon 1 were compared to the human promoter to identify conserved elements.
        
        
          Conclusions
          The human and mouse thioredoxin reductase 1 gene organisation is highly conserved and both genes exhibit alternative splicing at the 5' end. The mouse and human promoters share some conserved sequences.
Model-based cluster analysis of microarray gene-expression data

Background
          Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques have been widely applied in analyzing microarray gene-expression data. However, normal mixture model-based cluster analysis has not been widely used for such data, although it has a solid probabilistic foundation. Here, we introduce and illustrate its use in detecting differentially expressed genes. In particular, we do not cluster gene-expression patterns but a summary statistic, the t-statistic.
        
        
          Results
          The method is applied to a data set containing expression levels of 1,176 genes of rats with and without pneumococcal middle-ear infection. Three clusters were found, two of which contain more than 95% genes with almost no altered gene-expression levels, whereas the third one has 30 genes with more or less differential gene-expression levels.
        
        
          Conclusions
          Our results indicate that model-based clustering of t-statistics (and possibly other summary statistics) can be a useful statistical tool to exploit differential gene expression for microarray data.
Compound 530452: 4-Butylbenzoic acid, heptadecyl ester

Chemical compound data from PubChem database. IUPAC Name: heptadecyl 4-butylbenzoate. Molecular Formula: C28H48O2. Molecular Weight: 416.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528154: N-Picolyl-2-picolinamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(pyridin-2-ylmethyl)pyridine-2-carboximidamide. Molecular Formula: C12H12N4. Molecular Weight: 212.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Dapsone gel, 5%

Dapsone Gel 5% is a prescription topical medication containing dapsone, a sulfone antibiotic, used to treat acne vulgaris in adults and adolescents 12 years and older. It comes in gel form for skin application, manufactured by Trupharma, LLC, and available in 60g or 90g tubes. This information was generated using AI and is provided for informational and research purposes only.
A combined in vitro / in vivo selection for polymerases with novel promoter specificities

Background
          The DNA-dependent RNA polymerase from T7 bacteriophage (T7 RNAP) has been extensively characterized, and like other phage RNA polymerases it is highly specific for its promoter. A combined in vitro / in vivo selection method has been developed for the evolution of T7 RNA polymerases with altered promoter specificities. Large (103 – 106) polymerase libraries were made and cloned downstream of variant promoters. Those polymerase variants that can recognize variant promoters self-amplify both themselves and their attendent mRNAs in vivo. Following RT / PCR amplification in vitro, the most numerous polymerase genes are preferentially cloned and carried into subsequent rounds of selection.
        
        
          Results and Conclusions
          A T7 RNA polymerase library that was randomized at three positions was cloned adjacent to a T3-like promoter sequence, and a 'specialist' T7 RNA polymerase was identified. A library that was randomized at a different set of positions was cloned adjacent to a promoter library in which four positions had been randomized, and 'generalist' polymerases that could utilize a variety of T7 promoters were identified, including at least one polymerase with an apparently novel promoter specificity. This method may have applications for evolving other polymerase variants with novel phenotypes, such as the ability to incorporate modified nucleotides.
NSDUH 2020 In-Person Questionnaire

Browse the English in-person questionnaire for the 2020 National Survey on Drug Use and Health (NSDUH), as administered in Quarter 4 of 2020. The document provides the exact questions given to respondents in their full context, along with the skip patterns that determined whether a person was asked a question or not. There is also information on which sections were interviewer administered when conducted in-person, and a section that summarizes changes made to the questionnaire for 2020.
Relationships between volume and pressure measurements and stroke
		  volume in critically ill patients

Objective:
          To evaluate the relationships between the changes in stroke volume
				index (SVI), measured in both the aorta and the pulmonary artery, and the
				changes in intrathoracic blood volume index (ITBVI), as well as the
				relationship between changes in aortic SVI and changes in the pulmonary artery
				wedge pressure (PAWP).
        
        
          Design:
          Prospective study with measurements at predetermined
				intervals.
        
        
          Setting:
          Medical intensive care unit of a university hospital.
        
        
          Patients and methods:
          One hundred and fifty-four measurements were taken in 45
				critically ill patients with varying underlying disorders. Aortic SVI and
				pulmonary arterial SVI were determined with thermodilution. PAWP was measured
				using a pulmonary artery catheter. ITBVI was determined with thermal-dye
				dilution, using a commercially available computer system.
        
        
          Results:
          A good correlation was found between changes in ITBVI and changes
				in aortic SVI. However, this correlation weakened when changes in ITBVI were
				plotted against changes in pulmonary arterial SVI, which was in part probably
				due to mathematical coupling between ITBVI and aortic SVI. A good correlation
				between changes in ITBVI and changes in aortic SVI could also be established in
				most of the individual patients. No correlation was found between changes in
				PAWP and changes in aortic SVI.
        
        
          Conclusion:
          ITBVI seems to be a better predictor of SVI than PAWP. ITBVI may
				be more suitable than PAWP for assessing cardiac filling in clinical
				practice.
Compound 525778: 2-Butyl-4,5-diethyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2-butyl-4,5-diethyl-1,3-oxazole. Molecular Formula: C11H19NO. Molecular Weight: 181.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400175-T1: [Translated] LAWN POSTS WITH DOG ATTRACT FABRIC

An article useful for attracting canines and inducing them to eliminate in a preferred outdoor area, the article desirably having a molded polymeric body and a canine attractant dispersed within the body, coated on a portion of the body or contained inside a cavity in the body, the canine attractant being adapted for release into the surrounding atmosphere over a prolonged period. <IMAGE>
Patent AT-E400192-T1: [Translated] SMOKING DEVICE

A smoking article (10) includes a hollow cylindrical member (11) provided with a heat generating member (13) at its distal end portion and a mouthend portion (17) at its proximal end portion, and a flavor generating member (15) provided adjacent to the heat generating member (13) within the cylindrical member(11). The flavor generating member (15) includes a plurality of granules (151) each containing 65 to 93% by mass of a substantially non-porous inorganic filler material, 1 to 3% by mass of a binder and 6 to 32% by mass of a flavoring substance, on a dry mass basis. <IMAGE>
West (W)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for the west  (e.g., combines Alaska, Arizona, California, Colorado, Hawaii, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming) for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.