AndreaBozzo/ceres-open-data-index huggingface dataset:
NNDSS - TABLE 1A. Anthrax to Arboviral diseases, Eastern equine encephalitis virus disease

NNDSS - TABLE 1A. Anthrax to Arboviral diseases, Eastern equine encephalitis virus disease – 2020.  In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non U.S. residents.

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published.
NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2019 and 2020 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf.
†Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda2  protein

Background
          The reovirus λ2 protein catalyzes mRNA capping, that is, addition of a guanosine to the 5' end of each transcript in a 5'-to-5' orientation, as well as transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the N7 atom of the added guanosyl moiety and subsequently to the ribose 2'-O atom of the first template-encoded nucleotide. The structure of the human reovirus core has been solved at 3.6 Å resolution, revealing a series of domains that include a putative guanylyltransferase domain and two putative methyltransferase (MTase) domains. It has been suggested that the order of domains in the λ2 protein corresponds to the order of reactions in the pathway and that the m7G (cap 0) and the 2'-O-ribose (cap 1) MTase activities may be exerted by the MTase 1 and the MTase 2 domains, respectively.
        
        
          Results
          We show that the reovirus MTase 1 domain shares a putative active site with the structurally characterized 2'-O-ribose MTases, including vaccinia virus cap 1 MTase, whereas the MTase 2 domain is structurally similar to glycine N-MTase.
        
        
          Conclusions
          On the basis of our analysis of the structural details we propose that the previously suggested functional assignments of the MTase 1 and MTase 2 domains should be swapped.
Potentially Avoidable Antibiotic Prescribing Rates for Acute Respiratory Infection by Provider County, Children Age 3 Months-17 Years, NYS Medicaid: Beginning 2010

This dataset contains Potentially Avoidable Antibiotic Prescribing observed and risk-adjusted rates for child Medicaid enrollees by provider county beginning in 2010.

Potentially Avoidable Antibiotic Prescriptions are antibiotic prescriptions filled for the treatment of acute respiratory infections for which antibiotics are not indicated, contributing to bacterial drug resistance. Index visits for acute respiratory infections and corresponding prescription fills were identified through the use of previously published methods.   

The rates were calculated using Medicaid outpatient claims and encounters, and prescription drug data.  

The observed and risk adjusted rates are presented by provider county (including a statewide total).
Compound 525650: N,N-Dimethyl-N'-propyl-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-chloro-N,N-dimethyl-N'-propylbenzenecarboximidamide. Molecular Formula: C12H17ClN2. Molecular Weight: 224.73. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Pervasive influence of large-scale climate in the dynamics of a terrestrial vertebrate community

Background
          Large-scale climatic variability has been implicated in the population dynamics of many vertebrates throughout the Northern Hemisphere, but has not been demonstrated to directly influence dynamics at multiple trophic levels of any single system. Using data from Isle Royale, USA, comprising time series on the long-term dynamics at three trophic levels (wolves, moose, and balsam fir), we analyzed the relative contributions of density dependence, inter-specific interactions, and climate to the dynamics of each level of the community.
        
        
          Results
          Despite differences in dynamic complexity among the predator, herbivore, and vegetation levels, large-scale climatic variability influenced dynamics directly at all three levels. The strength of the climatic influence on dynamics was, however, strongest at the top and bottom trophic levels, where density dependence was weakest.
        
        
          Conclusions
          Because of the conflicting influences of environmental variability and intrinsic processes on population stability, a direct influence of climate on the dynamics at all three levels suggests that climate change may alter stability of this community. Theoretical considerations suggest that if it does, such alteration is most likely to result from changes in stability at the top or bottom trophic levels, where the influence of climate was strongest.
2014 CMHS Uniform Reporting System (URS) Table for Kansas

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Kansas. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
The effect of EGTA and Ca

Background
          The Na/K-ATPase activity of the brain synaptic plasma membranes (SPM) is regulated by noradrenaline (NA) and the synaptosomal factor SF (soluble protein obtained from the synaptosome cytosol). In the absence of SF, NA inhibits Na/K-ATPase, while, on addition of SF to the reaction medium, there is a NA-dependent activation of Na/K-ATPase . On the other hand, EGTA augments the Na/K-ATPase activity and attenuates the ability of NA to inhibit Na/K-ATPase.
        
        
          Results
          Considering that Ca2+ ion is a Na/K-ATPase modifier, it can be assumed that the effect of NA and SF is a Ca2+-dependent process. However, in the presence of 0.3 mM EGTA and 0.1 mM NA, the apparent inhibition constant for Ca2+ (at [Ca2+] > 0.3 mM) is not SF dependent, while the apparent activation constant for SF does not change at increasing Ca2+ concentration ([Ca2+] < 0.3 mM). At various Ca2+ concentrations (0.06, 0.35 and 0.6 mM), no significant changes occur in the mode of action of NA on the Na/K-ATPase activity in the presence of 5 μg/ml SF. EGTA also has no effect on the NA-independent activation of Na/K-ATPase evoked by high SF concentrations.
        
        
          Conclusions
          Taking into account that in the absence of EGTA similar results have been obtained, it can be concluded that the effect of NA and SF on brain Na/K-ATPase is a Ca2+-independent process.
SHIP Child maltreatment rate 2010-2022

This is historical data. The update frequency has been set to "Static Data" and is here for historic value. Updated on 8/14/2024

Child maltreatment rate - This indicator shows the rate of children who are maltreated per 1,000 population under the age of 18. Child abuse or neglect can result in physical harm, developmental delays, behavioral problems, or death. Abused and neglected children are at greater risk than other children for delinquency and mistreatment of their own children. <a href ="https://health.maryland.gov/pophealth/Documents/SHIP/SHIP%20Lite%20Data%20Details/Child%20Maltreatment%20Rate.pdf" > Link to Data Details </a>
Compound 527489: Cryptofauronol

Chemical compound data from PubChem database. IUPAC Name: 7,8-dimethyl-10-propan-2-yl-2-oxatricyclo[5.3.1.03,8]undecan-3-ol. Molecular Formula: C15H26O2. Molecular Weight: 238.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Publications Using SAMHSA Data2021-2022 NSDUH: State-Specific Tables

Browse population estimates based on the 2021-2022 National Surveys on Drug Use and Health (NSDUH) for each state and region. There are four tables for each geographic area, which present population estimates and percentages for 35 measures of substance use and mental health by age group across 37 tables. These estimates are based on small area estimation (SAE) methods in which state-level NSDUH data are combined with other data from smaller geographies. The combined data are used to create modeled state estimates of the civilian, noninstitutionalized population ages 12 and older, or adults 18 and older for mental health measures.The tables are available in a zip file of PDFs or as an HTML file. There is also a table of contents which contains links to specific state files in HTML or PDF.Tables labeled with an A include measures of substance use and mental health issues. Tables labeled with a B include measures of past year substance use and mental health treatment.
Compound 526701: Perfluoro-pentan ethioic acid S-butyl ester

Chemical compound data from PubChem database. IUPAC Name: S-butyl 2,2,3,3,4,4,5,5,5-nonafluoropentanethioate. Molecular Formula: C9H9F9OS. Molecular Weight: 336.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529955: 3-(2-Oxobutyldithio)butan-2-one

Chemical compound data from PubChem database. IUPAC Name: 1-(3-oxobutan-2-yldisulfanyl)butan-2-one. Molecular Formula: C8H14O2S2. Molecular Weight: 206.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
National Study of Protective, Preventive, and Reunification Services Delivered to Children and Their Families, 1994

The passage of the Adoption Assistance and Child Welfare Act of 1980 (P.L. 96-272) significantly reoriented child welfare services from a system which focused on foster care placement to one which was intended to provide the services necessary to maintain children in their own homes.  In response to the provisions of the law, state and county child welfare agencies developed new social service programs and sought new avenues for coordinating with other components of the human service delivery system.The purpose of the National Study of Protective, Preventive, and Reunification Services Delivered to Children and Their Families, 1994, is to provide a reliable national picture of the children and families in the ìnewî  child welfare system. The study is designed not only to describe the current delivery system in terms of the number and characteristics of the children and families served by service type, but also to examine how agency, service, and client characteristics relate to case status. The dataset consists of three files.  The main case file includes 2,109 observations and 1,205 variables.  It includes information about the number, types and services provided to children and their families, with an emphasis on differences in annual and point-in-time data, case duration, in-home and out-of-home services, race and kinship care.  Two additional files are provided to separate out the repeating records.  These files augment the main case file and contain 11,335 observations and 25 variables about household members and their characteristics and delineation of children receiving services.

Investigators: Maza, Penny
Detroit: Drug-Related Emergency Department Visits, 2004-2011 - Nonmedical Use of Pharmaceuticals

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving the nonmedical use of pharmaceuticals (prescription and over-the-counter medications and dietary supplements) for the Detroit metropolitan area, covering 2004-2011.  Nonmedical use includes patients who took a higher than prescribed or recommended dose of their own medication, patients who took a pharmaceutical prescribed for another person, malicious poisoning of the patient by another individual, and documented substance abuse involving pharmaceuticals
Monthly Cumulative Number and Percent of Children <20 Months Who Received Nirsevimab by Age Group and Jurisdiction, United States

Monthly Cumulative Number and Percent of Children <20 Months Who Received Nirsevimab by Age Group and Jurisdiction

• Estimated nirsevimab coverage for children 0-19 months is assessed through U.S. jurisdictions’ Immunization Information Systems (IIS) data, submitted from jurisdictions to CDC monthly in aggregate by age group. 

• Starting in July 2023, the CDC recommended the RSV vaccine to protect against serious illness from RSV. (https://www.cdc.gov/respiratory-viruses/whats-new/rsv-update-2023-09-22.html)
NNDSS - TABLE 1FF. Severe acute respiratory syndrome-associated coronavirus disease to Shigellosis

NNDSS - TABLE 1FF. Severe acute respiratory syndrome-associated coronavirus disease to Shigellosis - 2019. In this Table, provisional cases* of notifiable diseases are displayed for United States, U.S. territories, and Non-U.S. residents. 

Note: 
This table contains provisional cases of national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data from the 50 states, New York City, the District of Columbia and the U.S. territories are collated and published weekly on the NNDSS Data and Statistics web page (https://wwwn.cdc.gov/nndss/data-and-statistics.html). Cases reported by state health departments to CDC for weekly publication are provisional because of the time needed to complete case follow-up. Therefore, numbers presented in later weeks may reflect changes made to these counts as additional information becomes available. The national surveillance case definitions used to define a case are available on the NNDSS web site at https://wwwn.cdc.gov/nndss/. Information about the weekly provisional data and guides to interpreting data are available at: https://wwwn.cdc.gov/nndss/infectious-tables.html. 

Footnotes:
U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
-: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
NP: Nationally notifiable but not published — CDC does not have data because of changes in how conditions are categorized.
Cum: Cumulative year-to-date counts.
Max: Maximum — Maximum case count during the previous 52 weeks.
* Case counts for reporting years 2018 and 2019 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the US, a US territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-US Residents' category. For further information on interpretation of these data, see https://wwwn.cdc.gov/nndss/document/Users_guide_WONDER_tables_cleared_final.pdf. 
† Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
Patent AT-E401677-T1: [Translated] ANTENNA WITH AT LEAST ONE DIPOL OR A DIPOL-LIKE RADIATOR ARRANGEMENT

Disclosed is an antenna or antenna array comprising at least one dipole or a dipole-like radiator arrangement or radiator structure (11) and a reflector (3). Said antenna or antenna array has the following characteristics: the radiator arrangement (11) encompasses an electrically conductive support device (15) that is connected in a capacitively and/or galvanically contactless manner to the electrically conductive reflector (3); an electrically conductive rod-shaped coupling element (21) which extends perpendicular to the reflector plane is provided on the front face of the reflector (3); the support device (15) can be placed on said rod-shaped coupling element (21) with the aid of an internal axial bore in such a way that the support device (15) and the rod-shaped coupling element (21) are capacitively coupled without being in galvanic contact; the antenna is fed by means of a coaxial cable (31) whose outer conductor is connected to the reflector and/or the rod-shaped coupling element (21) and whose inner conductor is galvanically or capacitively connected to an opposite half-dipole.
Child Welfare Outcomes 2019: Report to Congress

This Report to Congress provides information on the performance of states on seven national outcome categories and also includes data on contextual factors and findings of analyses conducted across states.

Note: The PDF is best viewed in Chrome or Firefox. If using Internet Explorer (IE), please right click the link, save the file, and view it locally.

Appendix A: Adoption and Safe Families Act of 1997 (Pub. L. 105—89)

Appendix B: Child Welfare Outcomes Report: Outcomes and Measures

Appendix C: Caseworker Visits

Appendix D: Child Welfare Outcomes Report: Data Sources and Elements

Appendix E: Child Maltreatment 2019: Summary of Key Findings

Appendix F: The AFCARS Report: FY 2019 Estimates

Appendix G: Data-Quality Criteria

Metadata-only record linking to the original dataset. Open original dataset below.
2012 Uniform Reporting System (URS) Tables for Alabama

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Quantitation of the distribution and flux of myosin-II during cytokinesis

Background
          During cytokinesis, the cell's equator contracts against the cell's global stiffness. Identifying the biochemical basis for these mechanical parameters is essential for understanding how cells divide. To achieve this goal, the distribution and flux of the cell division machinery must be quantified. Here we report the first quantitative analysis of the distribution and flux of myosin-II, an essential element of the contractile ring.
        
        
          Results
          The fluxes of myosin-II in the furrow cortex, the polar cortex, and the cytoplasm were examined using ratio imaging of GFP fusion proteins expressed in Dictyostelium. The peak concentration of GFP-myosin-II in the furrow cortex is 1.8-fold higher than in the polar cortex and 2.0-fold higher than in the cytoplasm. The myosin-II in the furrow cortex, however, represents only 10% of the total cellular myosin-II. An estimate of the minimal amount of this motor needed to produce the required force for cell cleavage fits well with this 10% value. The cell may, therefore, regulate the amount of myosin-II sent to the furrow cortex in accordance with the amount needed there. Quantitation of the distribution and flux of a mutant myosin-II that is defective in phosphorylation-dependent thick filament disassembly confirms that heavy chain phosphorylation regulates normal recruitment to the furrow cortex.
        
        
          Conclusion
          The analysis indicates that myosin-II flux through the cleavage furrow cortex is regulated by thick filament phosphorylation. Further, the amount of myosin-II observed in the furrow cortex is in close agreement with the amount predicted to be required from a simple theoretical analysis.
Dermal exposure to the immunomodulatory antimicrobial chemical triclosan alters the skin barrier integrity and microbiome in mice

Triclosan is an antimicrobial chemical used in healthcare settings that can be absorbed through the skin. Exposure to triclosan has been positively associated with food and aeroallergy and asthma exacerbation in humans and, although not directly sensitizing, has been demonstrated to augment the allergic response in a mouse model of asthma. The skin barrier and microbiome are thought to play important roles in mediating inflammation and allergy and disruptions may contribute to development of allergic disease. To investigate potential connections of the skin barrier and microbiome with immune responses to triclosan, SKH1 mice were dermally exposed to triclosan (0.5-2%) or vehicle for up to 7 consecutive days.
Compound 525665: p-Bromobenzylidene-benzyl-amine

Chemical compound data from PubChem database. IUPAC Name: N-benzyl-1-(4-bromophenyl)methanimine. Molecular Formula: C14H12BrN. Molecular Weight: 274.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.