AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 528669: Benzeneacetic acid, 3,4-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-[3,4-bis(trimethylsilyloxy)phenyl]acetate. Molecular Formula: C17H32O4Si3. Molecular Weight: 384.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400579-T1: [Translated] METHOD FOR SEPARATING EXOCYCLIC BASE PROTECTION GROUPS

Nitrogen-protecting groups are removed from the exocyclic nucleobase portion of a 2′-O protected nucleotide or 2′-halo nucleotide by contacting the nucleotide with an inorganic base. Typical is the removal of t-butylphenoxyacetyl protecting groups from the nucleobase portion of a 2′-O protected nucleotide on which the 2′-O protecting group is t-butyldimethylsilyl, removal or deprotection being accomplished by contact with a potassium carbonate solution.
Compound 527771: 2,2-Dichloroethyl undecanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl undecanoate. Molecular Formula: C13H24Cl2O2. Molecular Weight: 283.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E400242-T1: [Translated] VISCOUS COMPOSITIONS CONTAINING CARBON DIOXIDE

The present invention relates to a carbon dioxide-containing viscous composition comprising an aqueous viscous composition containing one or more thickeners and carbon dioxide, wherein the aqueous viscous composition comprises the carbon dioxide in the form of bubbles, the carbon dioxide-containing viscous composition being characterized in that the thickener is at least one selected from the group consisting of ethyl cellulose, carboxymethyl cellulose and salts thereof, carboxy-methylethyl cellulose and salts thereof, croscarmellose and salts thereof, crystalline cellulose, cellulose acetate, cellulose acetate phthalate, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, hydroxypropylmethyl cellulose phthalate, powdered cellulose, methyl cellulose and methylhydroxypropyl cellulose; a kit comprising a carbonate or carbonates, an acid or acids, a thickener or thickeners and water in a state where the components produce substantially no carbon dioxide, which enables to produce a carbon dioxide-containing viscous composition comprising carbon dioxide bubbles according to the present invention by mixing the carbonate or carbonates, the acid or acids, the thickener or thickeners and water; a pharmaceutical composition comprising, as an active ingredient, the carbon dioxide-containing viscous composition according to the present invention or the carbon dioxide-containing viscous composition obtainable by the kit according to the present invention; and cosmetics comprising the carbon dioxide-containing viscous composition according to the present invention or the carbon dioxide-containing viscous composition obtainable by the kit according to the present invention.
Compound 526990: 1-Pentanamine, N-ethyl-N-pentyl

Chemical compound data from PubChem database. IUPAC Name: N-ethyl-N-pentylpentan-1-amine. Molecular Formula: C12H27N. Molecular Weight: 185.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Cardiac abnormalities in patients with mitochondrial DNA mutation 3243A>G

Background
          Tissues that depend on aerobic energy metabolism suffer most in diseases caused by mutations in mitochondrial DNA (mtDNA). Cardiac abnormalities have been described in many cases, but their frequency and clinical spectrum among patients with mtDNA mutations is unknown.
        
        
          Methods
          Thirty-nine patients with the 3243A>G mtDNA mutation were examined, methods used included clinical evaluation, electrocardiogram, Holter recording and echocardiography. Autopsy reports on 17 deceased subjects were also reviewed. The degree of 3243A>G mutation heteroplasmy was determined using an Apa I restriction fragment analysis. Better hearing level (BEHL0.5–4 kHz) was used as a measure of the clinical severity of disease.
        
        
          Results
          Left ventricular hypertrophy (LVH) was diagnosed in 19 patients (56%) by echocardiography and in six controls (15%) giving an odds ratio of 7.5 (95% confidence interval; 1.74–67). The dimensions of the left ventricle suggested a concentric hypertrophy. Left ventricular systolic or diastolic dysfunction was observed in 11 patients. Holter recording revealed frequent ventricular extrasystoles (>10/h) in five patients. Patients with LVH differed significantly from those without LVH in BEHL0.5–4 kHz, whereas the contribution of age or the degree of the mutant heteroplasmy in skeletal muscle to the risk of LVH was less remarkable.
        
        
          Conclusions
          Structural and functional abnormalities of the heart were common in patients with 3243A>G. The risk of LVH was related to the clinical severity of the phenotype, and to a lesser degree to age, suggesting that patients presenting with any symptoms from the mutation should also be evaluated for cardiac abnormalities.
Carboplatin

Carboplatin is a prescription chemotherapy drug used to treat certain cancers. It's administered intravenously as an injectable solution in strengths of 50mg/5ml, 150mg/15ml, or 450mg/45ml (all at 10mg/ml). Manufactured by Hospira, Inc., it's a platinum-based medication approved under ANDA076517. This information was generated using AI and is provided for informational and research purposes only.
δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines

Background
          Acute Intermittent Porphyria is a genetic disorder of heme metabolism, characterized by increased levels of porphyrin precursors, δ-aminolevulinic acid (ALA) and porphobilinogen (PBG). ALA has been reported to generate reactive oxygen species and to cause oxidative damage to proteins, subcellular structures and DNA. It is known that oxidative stress can induce apoptosis. The aim of this work was to study the cytotoxic effect of ALA on two hepatocarcinoma cell lines.
        
        
          Results
          We have determined the impact of ALA on HEP G2 and HEP 3B hepatocarcinoma cell lines survival as measured by the MTT assay. ALA proved to be cytotoxic in both cell lines however; HEP G2 was more sensitive to ALA than HEP 3B. Addition of hemin or glucose diminished ALA cytotoxicity in HEP G2 cells; instead it was enhanced in HEP 3B cells. Because apoptosis is usually associated with DNA fragmentation, the DNA of ALA treated and untreated cells were analyzed. The characteristic pattern of DNA fragmentation ladders was observed in ALA treated cells. To elucidate the mechanisms of ALA induced apoptosis, we examined its effect on p53 expression. No changes in p53 mRNA levels were observed after exposure of both cell lines to ALA for 24 h. CDK2 and CDK4 protein levels were reduced after ALA treatment at physiological concentrations.
Compound 525714: p-Methylbenzylidene-(3-methoxyphenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: N-(3-methoxyphenyl)-1-(4-methylphenyl)methanimine. Molecular Formula: C15H15NO. Molecular Weight: 225.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 529092: 4H-Cyclopenteno[2,3-e]pyrido[1,2-a]pyrimidin-4-one, 7-methyl

Chemical compound data from PubChem database. IUPAC Name: 12-methyl-1,8-diazatricyclo[7.4.0.03,7]trideca-3,6,8,10,12-pentaen-2-one. Molecular Formula: C12H10N2O. Molecular Weight: 198.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Treating patients with low high-density lipoprotein cholesterol: choices, issues and opportunities

Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein (HDL)-cholesterol. Two secondary prevention studies (Veterans Affairs HDL-Cholesterol Intervention Trial [VA-HIT] and Bezafibrate Infarction Prevention [BIP] trial) testified to the efficacy of fibrates in decreasing cardiovascular events, particularly in patients with coexisting risk factors, including hypertriglyceridaemia. The Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) demonstrated that a statin could decrease acute coronary events in patients with isolated low HDL-cholesterol in a primary prevention setting. The absolute risk reduction in coronary events in the VA-HIT study compares favourably with those reported from the statin-based Cholesterol and Recurrent Events (CARE) and Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) trials. The absolute risk reduction in AFCAPS-TexCAPS is similar to that in West of Scotland Coronary Pravastatin Study (WOSCOPS). Recommendations are given concerning lifestyle and pharmacological management of low HDL-cholesterol. Optimal management also requires review of current treatment targets for HDL-cholesterol and triglycerides levels.
2014 CMHS Uniform Reporting System (URS) Table for Virginia

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Virginia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.
Compound 526698: 4-O-acetyl-1,5-anhydro-2,3-di-O-methyl-D-fucitol

Chemical compound data from PubChem database. IUPAC Name: (4,5-dimethoxy-2-methyloxan-3-yl) acetate. Molecular Formula: C10H18O5. Molecular Weight: 218.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525658: p-Bromobenzylidene-(3-nitrophenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-(3-nitrophenyl)methanimine. Molecular Formula: C13H9BrN2O2. Molecular Weight: 305.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Patent AT-E401193-T1: [Translated] METHOD FOR PRODUCING A COMPOSITE MATERIAL FOR LOCKING ELEMENTS AND USE THEREOF

The invention relates to a composite material (1), for closure elements, mad from a support material (2) and a thermoplastically moulded layer (3) with projecting and recessed sections (4,5). According to the invention, the thermoplastically moulded layer (3) is thinner in the region of the recessed sections (4) than in the region of the projecting sections (5). Said surface structure may for example be produced by embossing by means of ribbed rollers or embossing plates. The composite material (1) is suitable for the production of sealing elements, such as for example, cup tops, usually stored in stacks. The cup elements stacked thus can easily be unstacked after stacking, precisely by means of said recessed or projecting sections(4, 5). On the side of the composite material facing the consumer a decorative and/or informative impression (6) can further be provided.
Identification and preliminary characterization of mouse

Background
          The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely distributed among metazoan phyla. Orthologous relationships have been defined for a few ADAM proteins including ADAM10 (Kuzbanian), and ADAM17 (TACE), but evolutionary relationships are not clear for the majority of family members. Human ADAM33 refers to a testis cDNA clone that does not contain a complete open reading frame, but portions of the predicted protein are similar to Xenopus laevis ADAM13.
        
        
          Results
          In a 48 kb region of mouse DNA adjacent to the Attractin gene on mouse chromosome 2, we identified sequences very similar to human ADAM33. A full-length mouse cDNA was identified by a combination of gene prediction programs and RT-PCR, and the probable full-length human cDNA was identified by comparison to human genomic sequence in the homologous region on chromosome 20p13. Mouse ADAM33 is 44% identical to Xenopus laevis ADAM13, however a phylogenetic alignment and consideration of functional domains suggests that the two genes are not orthologous. Mouse Adam33 is widely expressed, most highly in the adult brain, heart, kidney, lung and testis.
        
        
          Conclusions
          While mouse ADAM33 is similar to Xenopus ADAM13 in sequence, further examination of its embryonic expression pattern, catalytic activity and protein interactions will be required to assess the functional relationship between these two proteins. Adam33 is expressed in the mouse adult brain and could play a role in complex processes that require cell-cell communication.
Nuclear Receptor Signaling Atlas (NURSA)

<p>The Nuclear Receptor Signaling Atlas (NURSA) is designed to foster the development of a comprehensive understanding of the structure, function, and role in disease of nuclear receptors (NRs) and coregulators. NURSA seeks to elucidate the roles played by NRs and coregulators in metabolism and the development of metabolic disorders (including type 2 diabetes, obesity, osteoporosis, and lipid dysregulation), as well as in cardiovascular disease, oncology, regenerative medicine and the effects of environmental agents on their actions.</p>
Patent AT-E399573-T1: [Translated] BIOCOMPATIBLE POLYMER FILM

The present invention includes a co-polymer film which can be applied over a surface of an article to form a continuous surface that is more biocompatible and has a smoother surface morphology than an untreated article. In general the co-polymer film of the invention can be formed by providing a hydrophobic polymer block, such as polydimethylsiloxane (PDMS) with functional -OH end groups and reacting the -OH ends with a conventional monomer or prepolymer of a film-forming polymer capable of reacting with -OH groups. Such reactions are exemplified, using as reactive PDMS a triblock copolymer of the polylactone-polysiloxane-polylactone (PL-PDMS-PL) type, or silicone polyesters. The -OH groups of the polylactone blocks can react with any of a variety of isocyanates in a suitable solvent to form a polymer having PDMS incorporated with its structure. The film can be applied to the surface of an article by any convenient means of coating the article with the reaction mixture in solvent, and allowing the solvent to evaporate.
Compound 528448: 1-Heptadecene, 3,8,12,16-tetramethyl

Chemical compound data from PubChem database. IUPAC Name: 3,8,12,16-tetramethylheptadec-1-ene. Molecular Formula: C21H42. Molecular Weight: 294.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Analysis of EF-hand-containing proteins in

Three out of the four classes of Ca2+-binding proteins in plants contain Ca 2+ -binding EF-hand motif(s). A maximum of 250 proteins possibly having EF-hands were identified. Diverse proteins, including enzymes, proteins involved in transcription and translation, protein- and nucleic-acid-binding proteins and a large number of unknown proteins, have one or more putative EF-hands.
Compound 529468: Trifluoroacetamide, N-(1-methylheptyl)

Chemical compound data from PubChem database. IUPAC Name: 2,2,2-trifluoro-N-nonan-2-ylacetamide. Molecular Formula: C11H20F3NO. Molecular Weight: 239.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Improved analytical methods for microarray-based genome-composition analysis

Genome-composition analysis using microarrays can be used to categorize genes into 'present' and 'divergent' categories. This involves selecting a signal value that is used as a cutoff to discriminate present and divergent genes, but this can result in the misclassification of many genes. A method is described that depends on the shape of the signal-ratio distribution and does not require empirical determination of a cutoff. Many genes previously classified as present using static methods are in fact divergent on the basis of microarray signal; this is corrected by our algorithm.
Compound 528404: 2,4-Diethyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2,4-diethyl-1,3-oxazole. Molecular Formula: C7H11NO. Molecular Weight: 125.17. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527434: (p-Chloro-Benzoyl)-phosphonic acid dimethyl ester

Chemical compound data from PubChem database. IUPAC Name: (4-chlorophenyl)-dimethoxyphosphorylmethanone. Molecular Formula: C9H10ClO4P. Molecular Weight: 248.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528084: Carbamic acid, 2,4-dimethylphenyl, ethyl ester

Chemical compound data from PubChem database. IUPAC Name: ethyl N-(2,4-dimethylphenyl)carbamate. Molecular Formula: C11H15NO2. Molecular Weight: 193.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 527618: Acetic acid, trichloro-, 3-hexenyl ester

Chemical compound data from PubChem database. IUPAC Name: hex-3-enyl 2,2,2-trichloroacetate. Molecular Formula: C8H11Cl3O2. Molecular Weight: 245.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Idaho (ID)

This report presents Idaho\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Idaho for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.
MD COVID-19 - First Outreach Within 24 Hours of Case Entered into CovidLINK

<b>NOTE:</b>
THIS LAYER IS DEPRECATED (Last updated 6/7/2022). Was formerly updated weekly.

<b>Summary</b>
The daily percentage of confirmed COVID-19 cases that are entered into covidLINK that have received a ﬁrst contact tracing contact attempt within 24 hours of entry.

<b>Description</b>
The MD COVID-19 - First Outreach Within 24 Hours of Case Entered into CovidLINK data layer reflects the daily percentage of confirmed COVID-19 cases that are entered into covidLINK that have received a ﬁrst contact attempt within 24 hours of entry. The first outreach attempt is deﬁned as a documented phone call. Individuals that responded to outreach attempts were veriﬁed as the intended call recipient are considered successfully reached. Data are updated weekly on Wednesday during the 10 a.m. hour (data is reported through the previous Saturday).

<b>Terms of Use</b>
The Spatial Data, and the information therein, (collectively the "Data") is provided "as is" without warranty of any kind, either expressed, implied, or statutory. The user assumes the entire risk as to quality and performance of the Data. No guarantee of accuracy is granted, nor is any responsibility for reliance thereon assumed. In no event shall the State of Maryland be liable for direct, indirect, incidental, consequential or special damages of any kind. The State of Maryland does not accept liability for any damages or misrepresentation caused by inaccuracies in the Data or as a result to changes to the Data, nor is there responsibility assumed to maintain the Data in any manner or form. The Data can be freely distributed as long as the metadata entry is not modified or deleted. Any data derived from the Data must acknowledge the State of Maryland in the metadata.
Compound 526310: 2,3,4,6-Tetrabromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,3,4,6-tetrabromodibenzofuran. Molecular Formula: C12H4Br4O. Molecular Weight: 483.77. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
NNDSS - Table II. Lyme disease to Meningococcal

NNDSS - Table II. Lyme disease to Meningococcal - 2015.In this Table, provisional cases of selected notifiable diseases (≥1,000 cases reported during the preceding year), and selected low frequency diseases are displayed.The Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying MMWR data.  Data on United States exclude counts from US territories. Note:These are provisional cases of selected national notifiable diseases, from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly as numbered tables printed in the back of the Morbidity and Mortality Weekly Report (MMWR). Cases reported by state health departments to CDC for weekly publication are provisional because of ongoing revision of information and delayed reporting. Case counts in this table are presented as they were published in the MMWR issues. Therefore, numbers listed in later MMWR weeks may reflect changes made to these counts as additional information becomes available. Footnotes:C.N.M.I.: Commonwealth of Northern Mariana Islands. U: Unavailable.    -: No reported cases.    N: Not reportable.    NN: Not Nationally Notifiable.    NP: Nationally notifiable but not published.    Cum: Cumulative year-to-date counts.    Med: Median.    Max: Maximum. * Three low incidence conditions, rubella, rubella congenital, and tetanus, have been moved to Table 2 to facilitate case count verification with reporting jurisdictions. ��� Case counts for reporting year 2015 are provisional and subject to change. For further information on interpretation of these data, see http://wwwn.cdc.gov/nndss/document/ProvisionalNationaNotifiableDiseasesSurveillanceData20100927.pdf. Data for TB are displayed in Table IV, which appears quarterly. �� Data for meningococcal disease, invasive caused by serogroups ACWY; serogroup B; other serogroup; and unknown serogroup are available in Table I.
Cefixime

Cefixime is a generic prescription antibiotic, classified as a cephalosporin, available as an oral suspension in 100 mg/5mL and 200 mg/5mL strengths. Manufactured by Aurobindo Pharma Limited, it's used to treat certain bacterial infections and is dispensed as a powder that must be mixed into a liquid before use. This information was generated using AI and is provided for informational and research purposes only.