AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E401225-T1: [Translated] AUTOMATIC CENTER BUFFER COUPLING WITH AN ANTENNA FOR WIRELESS SIGNAL TRANSMISSION

An automatic central buffer coupling has signal transmission device (2) comprising coupling element (5) and counter-coupling element (5'). The coupling element is integrated in contact plate (4) of first coupling head (3) and the counter-coupling element is integrated in contact plate (4') of second coupling head (3') such that face side of coupling element is arranged opposite the face side of the counter-coupling element. The coupling element and the counter-coupling element each has antenna member (6, 6') comprising a disc monopole antenna configured to transmit data in GHz frequency range. An automatic central buffer coupling for a multimembered vehicle comprises a first coupling head of a first car body, and a second coupling head of a second car body. The first coupling head comprises a coupling element and a first contact plate. The second coupling head comprises a counter-coupling element and a second contact plate. A signal transmission device transmits electric and/or electronic signals between the first car body and the second car body, and comprises the coupling element and the counter-coupling element. The first coupling head and the second coupling head are configured such that a frictional connection can be produced in the coupled state between them. The coupling element is integrated in the first contact plate and the counter-coupling element is integrated in the second contact plate such that a face side of the coupling element is arranged in a contact plane common to the first coupling head and the second coupling head opposite a face side of the counter-coupling element. The coupling element comprises at least one antenna member arranged in the first contact plate, and the counter-coupling element comprises at least one antenna member arranged in the second contact plate. The antenna members of the coupling element and the counter-coupling element are configured such that a clearance results between them when the first coupling head and the second coupling head are in the coupled state. Each of the antenna members comprises a disc monopole antenna configured to transmit data in the GHz frequency range. Each of the antenna members is configured such that the total attenuation occurring during data transmission does not exceed 77 dB. Coaxial cables couple the antenna members to the electronic units, and comprise RG-213 coaxial cable having an N-type plug and socket.
Patent AT-E401439-T1: [Translated] DEVICE FOR GRABING AN UNDERWOUND THREAD IN A RING SPINNING MACHINE

A device for gripping the underwinding yarn for a ring spinning frame comprises a collar (14) fixed to the spindle (2), a sleeve (24) able to slide axially and a bar (40) supported by a pair of pneumatic actuators.  The support axis (Z-Z) of the bar (40), defined by the points where the bar is supported by the actuators (70a,70b), intersects the active portions (42) of the bar (40) that engage with the sleeve (24) in order to stiffen the bar (40), and simultaneously open the sleeves (24) of the spindles of the spinning frame.  The engagement portions (70a,70b) of the bar (40) that engage with the actuators are longitudinally separated from its active portions (42) in order to make the spinning frame compact and make the presence of the actuators compatible with the wharves (10) of the spindles (2) and with the drive means by which they are turned.  The bar (40) moves vertically in order to engage/disengage the spindle (2).
Chicago: Drug-Related Emergency Department Visits, 2004-2011 - Seeking Detox

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving patients seeking detox in the Chicago metropolitan area, covering 2004-2011. This includes nonemergency requests made through the ED for admission to detoxification unit, visits to obtain medical clearance before being incarcerated, and acute emergencies where an individual is experiencing withdrawal symptoms and requests detox. These estimates do not include patients who seek or enter the hospital\'s detox unit through other avenues.
Patent AT-E401371-T1: [Translated] ADHESIVE COMPOSITION AND SKIN PLASTER

It is intended to provide a composition which has well-balanced pressure-sensitive adhesiveness and cohesive force as well as favorable application properties to the skin, and a patch which has the above-described characteristics and hardly peels off. This object can be achieved by providing a composition comprising an acrylic copolymer containing from 3 to 25% by weight of hydroxyethyl (meth)acrylate as a constituent, a plasticizer and a pseudo-crosslinking compound, wherein the ratio of the content of the plasticizer to the content of the pseudo-crosslinking compound ranges from 30:1 to 250:1, and a patch.
Lack of correlation between Ki-67 labelling index and tumor size of anterior pituitary adenomas

Aims and background
          The Ki-67 is a nuclear antigen detected by the monoclonal antibody MIB-1 and its Labeling Index (LI) is considered a marker of normal and abnormal cell proliferation. Pituitary adenomas are generally well differentiated neoplasms, even if in about one third of cases they are invasive of surrounding tissues. The aim of this study is to evaluate the correlation between Ki-67 labelling index and tumor size of pituitary adenomas extimated by means CT and MRI and confirmed at operation.
        
        
          Methods
          Using the monoclonal antibody MIB-1, we evaluated the expression of Ki-67 in 121 anterior pituitary adenomas consecutively operated on in a 48-month period.
        
        
          Results
          In relation to neuroradiological (CT and MRI) and surgically verified tumor size, we identified 24 microadenomas, 27 intrasellar macroadenomas, 34 intra-suprasellar macroadenomas, and 36 intra-supra-parasellar macroadenomas. The adenomas were non-infiltrating (76 cases) and infiltrating (45 cases) adenomas. The wall of the cavernous sinus (CS) was infiltrated in 18 cases. Forty-eight adenomas were non-functioning and 73 functioning. The overall mean ± SD Ki-67 LI was 2.72 ± 2.49% (median 1.6). It was 2.59 ± 1.81 in microadenomas, 2.63 ± 3.45 in intrasellar macroadenomas, 1.91 ± 2.11 in intra-suprasellar macroadenomas, and 3.29 ± 5.45 in intra-supra-parasellar macroadenomas (p = 0.27). It was 3.73 ± 5.13% in infiltrating and 2.03 ± 2.41% in non-infiltrating adenomas (p = 0.02), and 5.61 ± 7.19% in CS-infiltrating versus 2.09 ± 2.37% in CS-non-infiltrating adenomas (p = 0.0005).
        
        
          Conclusions
          Our preliminary results seem to exclude significative correlations between Ki-67 LI and tumor size of anterior pituitary adenomas, even if this index can be considered a useful marker in the determination of the infiltrative behaviour of these tumors.
Compound 528108: 2,3-Dimethyl-5-(2-methylpropyl)pyrazine

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethyl-5-(2-methylpropyl)pyrazine. Molecular Formula: C10H16N2. Molecular Weight: 164.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525437: 3,5-Dithiaoctane

Chemical compound data from PubChem database. IUPAC Name: 1-(ethylsulfanylmethylsulfanyl)propane. Molecular Formula: C6H14S2. Molecular Weight: 150.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 528848: Glycerol, 2,3-dimethyl,1-tridecanoate

Chemical compound data from PubChem database. IUPAC Name: 2,3-dimethoxypropyl tridecanoate. Molecular Formula: C18H36O4. Molecular Weight: 316.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Weekly Cumulative Doses (in Millions) of Influenza Vaccine Distributed by Flu Season in the United States

Weekly Cumulative Doses (in Millions) of Influenza Vaccine Distributed by Flu Season in the United States

•  Archived data are available here:  https://data.cdc.gov/resource/e5zk-7tx5 
•  Flu vaccine is produced by private manufacturers, so supply depends on manufacturers. Vaccine manufacturers have projected that they will supply the United States with as many as 173.5 million to 183.5 million doses of influenza vaccines for the 2022-2023 season. 
•  Additional information is available: https://www.cdc.gov/flu/prevent/vaccine-supply-distribution.htm.
Apoptosis and signalling in acid sphingomyelinase deficient cells

Background
          Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell surface to the cytoplasmic leaftet of the plasma membrane. Inner leaflet sphingomyelin is then cleaved to ceramide by a neutral sphingomyelinase. The production of this non-membrane forming lipid induces blebbing of the plasma membrane to aid rapid engulfment by professional phagocytes. However contrary evidence suggests that cells which are deficient in acid sphingomyelinase are defective in apoptosis signalling. This data has been interpreted as support for the activation of acid sphingomyelinase as an early signal in apoptosis.
        
        
          Hypothesis
          An alternative explanation is put forward whereby the accumulation of intracellular sphingomyelin in sphingomyelinase deficient cells leads to the formation of intracellular rafts which lead to the sequestration of important signalling molecules that are normally present on the cell surface where they perform their function.
        
        
          Testing the hypothesis
          It is expected that the subcellular distribution of important signalling molecules is altered in acid sphingomyelinase deficient cells, leading to their sequestration in late endosomes / lysosomes. Other sphingolipid storage diseases such as Niemann-Pick type C which have normal acid sphingomyelinase activity would also be expected to show the same phenotype.
        
        
          Implications of the hypothesis
          If true the hypothesis would provide a mechanism for the pathology of the sphingolipid storage diseases at the cellular level and also have implications for the role of ceramide in apoptosis.
Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder

Idiopathic pulmonary fibrosis is a chronic and usually progressive lung disorder of unknown etiology. A growing body of evidence suggests that, in contrast to other interstitial lung diseases, IPF is a distinct entity in which inflammation is a secondary and non-relevant pathogenic partner. Evidence includes the presence of similar mild/moderate inflammation either in early or late disease, and the lack of response to potent anti-inflammatory therapy. Additionally, it is clear from experimental models and some human diseases that it is possible to have fibrosis without inflammation. An evolving hypothesis proposes that IPF may result from epithelial micro-injuries and abnormal wound healing.
Patent AT-E400810-T1: [Translated] INORGANIC NANOCRYSTALS WITH AN ORGANIC COATING AND THEIR PREPARATION PROCESS

The nanocrystals comprising a metal and/or a semi-conductor are coated with an organic material comprising a ligand. The nanocrystal comprises an inorganic core consisting of a metal and/or metal semi-conductor, the external surface being coated with an organic material constituted by a ligand of formula : X-Y-Z (I) : in which X is a 1,1-dithiolate or 1,1-diselenoate group linked by the two atoms of S or Se to a metal atom at the external surface, Y is a spacer group, to allow transfer of charge or an isolating group, and Z is a group which is capable of producing certain specific properties to the nanocrystal. An independent claim is also included for the preparation of the compounds.
Patent AT-E399578-T1: [Translated] IMPLANTABLE MEDICAL DEVICE WITH DELAY RECHARGE

In the embodiment of the invention, apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an Implantable Neurological Stimulator (INS). The embodiment provides a time delay interval between a first stimulation pulse and a recharging of the apparatus, in which the time delay interval is adjustable. The embodiment utilizes apparatus comprising a waveform controller and a waveform generator that is controlled by the waveform controller. With a variation of the embodiment, the apparatus utilizes passive recharging. In another variation of the embodiment, the apparatus utilizes a second stimulation to balance an accumulated charge. In another embodiment of the invention, a clinician is able to adjust the time delay interval through a telemetry channel. The waveform controller receives information about the time delay interval, and the waveform control instructs the waveform generator to adjust the time delay interval.
Deficiency ofPtenaccelerates mammary oncogenesis in MMTV-Wnt-1transgenic mice

Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic human breast cancer. GermlinePtenmutations in mice lead to the development of a variety of tumors, but mammary carcinomas are infrequently found, especially in mice under the age of six months.
A role for the collagen I/III and MMP-1/-13 genes in primary inguinal hernia?

Background
          Abnormal collagen metabolism is thought to play an important role in the development of primary inguinal hernia. This is underlined by detection of altered collagen metabolism and structural changes of the tissue in patients with primary inguinal hernia. However, it is still unknown whether these alterations reflect a basic dysfunction of the collagen synthesis, or of collagen degradation.
        
        
          Methods
          In the present study, we analysed type I and type III procollagen messenger ribonucleic acid (mRNA) and MMP-1 and MMP-13 mRNA in cultured fibroblasts from the skin of patients with primary inguinal hernia, and from patients without hernia (controls) by reverse transcription polymerase chain reaction (RT-PCR) and Northern Blot.
        
        
          Results
          The results indicated that the ratio of type I to type III procollagen mRNA was decreased in patients with primary hernia, showing significant differences as compared to controls (p = 0.01). This decrease was mainly due to the increase of type III procollagen mRNA. Furthermore, RT-PCR analysis revealed that the expression of MMP-1 mRNA in patients with primary hernia is equivalent to that of controls (p > 0.05). In addition, MMP-13 mRNA is expressed neither in patients with primary hernia nor in controls.
        
        
          Conclusion
          We concluded that abnormal change of type I and type III collagen mRNAs contribute to the development of primary inguinal hernia, whereas the expressions of MMP-1 and MMP-13 mRNA appears not to be involved in the development of primary inguinal hernia. Thus, the knowledge on the transcriptional regulation of collagen in patients with primary inguinal hernia may help to understand the pathogenesis of primary inguinal hernia, and implies new therapeutic strategies for this disease.
Compound 525398: 2,8-Dimethyl-3,7-dithianonane

Chemical compound data from PubChem database. IUPAC Name: 1,3-bis(propan-2-ylsulfanyl)propane. Molecular Formula: C9H20S2. Molecular Weight: 192.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525883: N,N-Dimethyl-N'-(4-bromophenyl)-pivalamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-bromophenyl)-N,N,2,2-tetramethylpropanimidamide. Molecular Formula: C13H19BrN2. Molecular Weight: 283.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Program Instruction (PI-09-07)

This Program Instruction (PI) provides instruction to Tribes on the June 30, 2009 Submission of: (1) the Child and Family Services Plan (CFSP) Final Report for fiscal years (FYs) 2005-2009; (2) the Child and Family Services Plan for FYs 2010-2014 for the Stephanie Tubbs Jones Child Welfare Services and Promoting Safe and Stable Families (PSSF) Programs, and the Chafee Foster Care Independence Program (CFCIP) and the Education and Training Vouchers (ETV) Programs; and (3) the CFS-101, Part I, Annual Budget Request, Part II, Annual Summary of Child and Family Services, and Part III, Annual Expenditure Report—Title IV-B, Subparts 1 and 2.

Metadata-only record linking to the original dataset. Open original dataset below.
MD COVID-19 - Total Vaccinations Statewide

Regarding all Vaccination Data
The date of Last Update is 4/21/2023. Additionally on 4/27/2023 several COVID-19 datasets were retired and no longer included in public COVID-19 data dissemination.

See this link for more information
https://imap.maryland.gov/pages/covid-data

<b>Summary</b>
The cumulative number of COVID-19 vaccinations in Maryland: First dose, second dose, single dose, total vaccinations.

<b>Description</b>
The MD COVID-19 - Total Vaccinations Statewide data layer is a collection of the statewide COVID-19 vaccinations that have been reported each day into ImmuNet. Doses administered also account for doses of vaccine provided to the District of Columbia to vaccinate Maryland residents who work in DC.

<b>Terms of Use</b>
The Spatial Data, and the information therein, (collectively the "Data") is provided "as is" without warranty of any kind, either expressed, implied, or statutory. The user assumes the entire risk as to quality and performance of the Data. No guarantee of accuracy is granted, nor is any responsibility for reliance thereon assumed. In no event shall the State of Maryland be liable for direct, indirect, incidental, consequential or special damages of any kind. The State of Maryland does not accept liability for any damages or misrepresentation caused by inaccuracies in the Data or as a result to changes to the Data, nor is there responsibility assumed to maintain the Data in any manner or form. The Data can be freely distributed as long as the metadata entry is not modified or deleted. Any data derived from the Data must acknowledge the State of Maryland in the metadata.
Compound 528987: 1,2-Tricosanediol, di-TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(1-trimethylsilyloxytricosan-2-yloxy)silane. Molecular Formula: C29H64O2Si2. Molecular Weight: 501.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Behavioral Health Barometer: Region 8, Volume 7

Explore state and regional data for HHS Region 8 with this user-friendly behavioral health report. It uses data from the 2021-2022 National Surveys on Drug Use and Health (NSDUH). The topics addressed in this report include substance use, substance use disorders, and mental health. Selected estimates are provided for adolescents aged 12 to 17, underage people aged 12 to 20, adults aged 18 or older, and the general population aged 12 or older. Statistical tests compare population percentages of (1) HHS region versus national estimates, (2) state versus national estimates, and (3) state versus HHS region estimates.
Compound 526328: 2,3-Dibromo-dibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 2,3-dibromodibenzofuran. Molecular Formula: C12H6Br2O. Molecular Weight: 325.98. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
CFSR Reviewer Qualifications

The Child Welfare Reviews Project assists the Children's Bureau in recruiting and maintaining a national pool of Child and Family Services Review (CFSR) reviewers, who are qualified child welfare professionals who meet established minimum education and experience requirements. The qualifications for individuals interested in participating as CFSR Reviewers are discussed below.

CFSR reviewers, quality assurance specialists, and note-taking specialists (collectively referred to as “agile staff”) are child welfare experts with experience in making professional judgments based on information collected from various sources. They apply this knowledge to participate in the CFSRs. The following are the minimum qualifications for agile staff:

The following are the preferred qualifications for CFSR reviewers:

Preference will be given to individuals who are experienced in applying the Onsite Review Instrument and Instructions and/or demonstrate fluency in Spanish and/or lived experience within the child welfare system or within indigenous or tribal social services.

Metadata-only record linking to the original dataset. Open original dataset below.
Availability of Fiscal Year (FY) 2024 Funds Under the Community-Based Grants for the Prevention of Child Abuse and Neglect Program

This Program Instruction (PI) sets forth the requirements for recipients of Community-Based Grants for the Prevention of Child Abuse and Neglect awards for FY 2024 and provides guidance and instructions for the preparation and submission of the application and annual reports.

Metadata-only record linking to the original dataset. Open original dataset below.
Compound 525780: 2-Ethyl-4-methyl-5-propyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2-ethyl-4-methyl-5-propyl-1,3-oxazole. Molecular Formula: C9H15NO. Molecular Weight: 153.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Compound 525164: Heptapropylene glycol, monoallyl ether, acetate

Chemical compound data from PubChem database. IUPAC Name: 1-[1-[1-[1-[1-[1-(1-prop-2-enoxypropan-2-yloxy)propan-2-yloxy]propan-2-yloxy]propan-2-yloxy]propan-2-yloxy]propan-2-yloxy]propan-2-yl acetate. Molecular Formula: C26H50O9. Molecular Weight: 506.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.
Persisting Cryptococcus Yeast Species Vishniacozyma victoriae and Cryptococcus neoformans Elicit Unique Airway Inflammation in Mice Following Repeated Exposure

Allergic airway diseases are a growing concern in industrialized nations and can be influenced by fungal exposures. Pathogenic yeast species such as Cryptococcus neoformans are known to exacerbate allergic airway disease. Recent indoor assessments have identified Basidiomycota yeasts, including non-pathogenic species such as Vishniacozyma victoriae (syn. Cryptococcus victoriae), to be prevalent and potentially associated with asthma. However, the pulmonary immune response to repeated V. victoriae exposure was previously unexplored. This study aimed to compare the immunological impact of repeated pulmonary exposure to pathogenic and non-pathogenic Cryptococcus yeasts. Mice were repeatedly exposed to either C. neoformans, V. victoriae, or PBS control, and the immune responses were analyzed by measuring histopathological scores, and quantifications of immune cells in the bronchoalveolar lavage fluid or lung via flow cytometry, and cytokine concentrations in the lung. These findings highlight the importance of in vivo characterizations of exposures to frequently detected fungal organisms.