AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 526179: 3-Methyl-4-oxo-1,2-dithiane

Chemical compound data from PubChem database. IUPAC Name: 3-methyldithian-4-one. Molecular Formula: C5H8OS2. Molecular Weight: 148.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525813: N-Phenyl-N'-3-bromophenylformamidine

Chemical compound data from PubChem database. IUPAC Name: N-(3-bromophenyl)-N'-phenylmethanimidamide. Molecular Formula: C13H11BrN2. Molecular Weight: 275.14. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E401131-T1: [Translated] PROCESSING APPARATUS FOR MEDICINAL PRODUCTS AND METHOD

This disclosure relates to a centrifugal vortex system for preparing a liquid, such as fuel and includes a chamber housing defining a vortex chamber. An array of tangential apertures are formed in the chamber housing to permit fluid to be turbulently introduced into the vortex chamber to create a vortical flow of fluid through the vortex chamber. In one embodiment, a plurality of vortex chambers are arranged in series to allow the fluid to pass through several vortex chambers. In other embodiments, the chamber housing may be stepped, textured, or both to increase the turbulence of the flow through the chamber. In yet another embodiment, a pressure differential supply jacket is provided to normalize the amount of flow through the tangential apertures according to the location of the apertures. A centrifuge chamber is also disclosed which has a plurality of output conduits on a bottom surface and a tapered extension member downwardly extending from a top surface to enhance the centrifugal flow of the fluid. Additionally, a bypass conduit is provided to selectively permit the flow to bypass one or more chambers.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 525823: N,N-Dimethyl-N'-(3-bromophenyl)-propionamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(3-bromophenyl)-N,N-dimethylpropanimidamide. Molecular Formula: C11H15BrN2. Molecular Weight: 255.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Time between Termination of Parental Rights (TPR) and Adoption Finalization Of Those Children Adopted During FY 2013

This report provides state-specific data from fiscal year 2013 about the time between the termination of parental rights and the adoption finalization for public agency adoptions.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, data, fiscal, policy, reporting
Organization: U.S. Department of Health & Human Services
Compound 529744: 1-Methyltetradecyl cyclopentanecarboxylate

Chemical compound data from PubChem database. IUPAC Name: 1-[(2-methylfuran-3-yl)disulfanyl]propan-2-one. Molecular Formula: C8H10O2S2. Molecular Weight: 202.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527571: 1-Bromo-4-methylcyclohex-1-ene

Chemical compound data from PubChem database. IUPAC Name: 1-bromo-4-methylcyclohexene. Molecular Formula: C7H11Br. Molecular Weight: 175.07. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E401576-T1: [Translated] USE OF A NUCLEAR-RESTRICTED PROTEIN FOR THE DIAGNOSIS AND THERAPY OF ALZHEIMER'S DISEASE AND RELATED DEEP NEURODEGENERATION DISORDERS

The present invention discloses the differential expression of the gene coding for the nuclear restricted protein/brain, NRP/B, in specific brain regions of Alzheimer's disease patients. Based on this finding this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using a gene coding for a nuclear restricted protein, in particular the nuclear restricted protein/brain, NRP/B. A method of screening for modulating agents of neurodegenerative diseases is also disclosed.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E400259-T1: [Translated] USE OF COLIPASE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OF OBESITY

The present invention relates to novel colipase-lipase inhibitors of the general formulae to be used in the treatment of prophylaxis of obesity, as well as pharmaceutical compositions containing the same, and method for treating obesity using said compounds.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 529497: Pentan-2-yl 3-methylbutanoate

Chemical compound data from PubChem database. IUPAC Name: pentan-2-yl 3-methylbutanoate. Molecular Formula: C10H20O2. Molecular Weight: 172.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400315-T1: [Translated] DEVICE FOR TREATING A WOUND

A control system (2) for use with a vacuum bandage (14) over a wound (300) includes a vacuum pump (110), a waste canister (26) operably coupled to the pump (110), and a fluid source (24). The canister (26) is coupled to the bandage (14) such that, when a vacuum is applied to the canister (26), the vacuum is applied to the bandage (14). The fluid source (22) is coupled to the bandage (14) to selectively introduce fluid into the wound (300) and the fluid source is coupled to a post (514) and held at an elevated position relative to the housing (4) of the control system.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 527707: 1,2,3,8-Tetrachlorodibenzofuran

Chemical compound data from PubChem database. IUPAC Name: 1,2,3,8-tetrachlorodibenzofuran. Molecular Formula: C12H4Cl4O. Molecular Weight: 306.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400098-T1: [Translated] METHOD FOR CONTROLLING RADIO MEANS

A method and apparatus is provided for transmitting a single counting end message to reject RRC connection requests of a plurality of terminals and for providing a quick response to terminals that transmitted a connection request. RRC connection request messages are sent by a plurality of terminals to a network in response to an RRC connection-required message received on a first channel. Each terminal monitors a second channel for an RRC connection setup message. The network establishes connections with a predetermined number of terminals by transmitting an RRC connection setup message on the second channel and transmits a single RRC connection-not-required message to the plurality of terminals on the first channel. Each terminal not receiving an RRC connection setup message after a predetermined period of time then terminates the network connection procedure and does not re-transmit an RRC connection request message after receiving the RRC connection-not-required message.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 530609: 3-Cyclopentylpropionic acid, 3-methylbut-2-enyl ester

Chemical compound data from PubChem database. IUPAC Name: 3-methylbut-2-enyl 3-cyclopentylpropanoate. Molecular Formula: C13H22O2. Molecular Weight: 210.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 530123: Tryptophan, 5-hydroxy, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 2-(trimethylsilylamino)-3-(5-trimethylsilyloxy-1H-indol-3-yl)propanoate. Molecular Formula: C20H36N2O3Si3. Molecular Weight: 436.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 529014: 1,5-Dimethyl-2,4-diethylbenzene

Chemical compound data from PubChem database. IUPAC Name: 1,5-diethyl-2,4-dimethylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526071: 1-Octadecanol, 16-methyl, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(16-methyloctadecoxy)silane. Molecular Formula: C22H48OSi. Molecular Weight: 356.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525728: (p-Methylbenzylidene)-nonyl-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-methylphenyl)-N-nonylmethanimine. Molecular Formula: C17H27N. Molecular Weight: 245.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528983: 1,2-Octacosanediol, di-TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(1-trimethylsilyloxyoctacosan-2-yloxy)silane. Molecular Formula: C34H74O2Si2. Molecular Weight: 571.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526793: 5-Hydroxy-nonadecanoic, delta-lactone

Chemical compound data from PubChem database. IUPAC Name: 6-tetradecyloxan-2-one. Molecular Formula: C19H36O2. Molecular Weight: 296.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 530347: Tridecane, 7-butyl

Chemical compound data from PubChem database. IUPAC Name: 7-butyltridecane. Molecular Formula: C17H36. Molecular Weight: 240.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400650-T1: [Translated] METHOD FOR PRODUCING NUCLEIC ACID MOLECULES

Manufacturing a nucleic acid molecule comprising employing at least partially double-stranded oligonucleotide comprising a modification allowing the oligonucleotide to be coupled to a surface, a recognition site for a first type IIS restriction enzyme that cuts outside its recognition site, and a single-stranded overhang, is new. Manufacturing a nucleic acid molecule comprises: (a) providing a first at least partially double-stranded oligonucleotide which has a modification allowing the oligonucleotide to be coupled to a surface, comprises a recognition site for a first type IIS restriction enzyme that cuts outside its recognition site, and comprises a single-stranded overhang; (b) providing a second at least partially double-stranded oligonucleotide, which comprises a recognition site, its part or its complementary sequence, for a second type IIS restriction enzyme which cuts outside its recognition site, and comprises a single-stranded overhang; (c) ligating the first and the second oligonucleotide via their overhangs to generate a first ligation product; (d) immobilizing the first ligation product to the surface via the modification; (e) cutting the immobilized ligation product with the first type IIS restriction enzyme to release an elongated oligonucleotide having an overhang; (f) combining the elongated oligonucleotide with a further at least partially double-stranded oligonucleotide, which has a modification allowing the oligonucleotide to be coupled to a surface, a recognition site for a further type IIS restriction enzyme that cuts outside its recognition site, and a single-stranded overhang, and ligating the elongated second oligonucleotide and the further at least partially double-stranded oligonucleotide via their overhangs to form a further ligation product; (g) immobilizing the further ligation product to a surface via the modification; (h) cutting the further ligation product with the further type IIS restriction enzyme to release an elongated oligonucleotide having an overhang; and (i) optionally, repeating steps (f)-(h).

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E399541-T1: [Translated] EPIDERMAL GROWTH FACTOR RECEPTOR ANTAGONISTS FOR THE TREATMENT OF HIGHLY INCREASE MUCUS SECRETION IN THE LUNGS

Chemical patent from PubChem database. Patent Number: AT-E399541-T1. Title: Method of Treatment Using Chemical Compounds. Filing Date: 2014-06-26. Inventors: Patel, Amit, Jones, Michael. Abstract: Methods for treating diseases using specific chemical compounds are provided, including dosing regimens and combination therapies for enhanced therape... IPC Classifications: C07C, C07B, A61K. This patent covers 20 claims related to 9 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E400238-T1: [Translated] SPINAL OSTEOSYNTHESIS DEVICE COMPRISING A CAGE, A FRONT PLATE AND TWO LONGITUDINAL RODS

A vertebral column osteosynthesis device of the type comprising at least one cage (1, 13) Containing a bone graft that will be substituted for at least one vertebra and the vertebrae (C2, C4, C7) between which the cage (1, 13) is placed, are fused with at least one anterior plate (17) that will be fixed to the said vertebrae (C2, C4) between which is cased the said case (1,13) or at least one of the said cages (1, 13) is placed, characterized in that the said device also comprises: Means (24, 25) of attachment of the said anterior plate (17) or at least one of the said anterior plates (17) to the cage (1) facing it; Two longitudinal rods (35, 36) that will extend along the vertebral column on each side of the processus spinosus, means of attachment of the ends of the said rods to healthy ends of the patient's skeleton, and means of connection of each rod to the said cage (1, 13) or to at least one of the said cages (1, 13).

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E400161-T1: [Translated] ELECTRIC HEATING UNIT HOUSED IN A CALORIE BATTERY BLOCK

Heating device having an electric heating body arranged within an accumulator block. The electric heating body includes an insulated flat resister. The accumulator block is structured and arranged to store calories. The heating device is adapted for use in a heating apparatus. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E399789-T1: [Translated] PRODUCTION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES

A process for the production of new partially hydrogenated metallocene complexes comprises reaction of optionally bridged transition metal complexes with cyclopentadienyl derivatives and at least partial hydrogenation with hydrogen in the presence of a catalyst.  A process for the production of partially hydrogenated metallocene complexes (I) comprises reaction of optionally bridged transition metal complexes of formula (1) with cyclopentadienyl derivatives of formula (2) at -78 to +250 degreesC, optionally in the presence of radicals or radical initiators to form a complex of formula (3) and at least partial hydrogenation with hydrogen in the presence of a catalyst. M  =  Ti, Hf, V, Nb, Ta, Cr, Mo, W, a Group 3 element or a lanthanide;  X  =  F, Cl, Br, I, H, 1-10C alkyl, 6-15C aryl, (1-10C)alkyl-(6-20C)aryl, -OR10 or -NR10R11;  n  =  1-4;  R1-R8, R', R  =  H, halo, 1-20C alkyl, 3-8 membered cycloalkyl optionally substituted by 1-10C alkyl, 6-15C aryl, (1-10C)alkyl-(6-20C)aryl, and neighboring R2-R7 optionally form 4-15C optionally unsaturated cyclic groups, -Si(R9)3, -OR10, -SR10, -N(R10)2 or -P(R10)2, optionally substituted by heteroatoms;  R9  =  1-20C alkyl, 3-6C cycloalkyl or 6-15C aryl optionally substituted by heteroatoms;  R10  =  1-10C alkyl, 6-15C aryl, 3-10C cycloalkyl, alkylaryl or Si(R)3;  R11  =  1-10C alkyl, 6-15C aryl, 3-10C cycloalkyl or alkylaryl;  Y, Y1  =  formula (4)-(9), =BR12, =AlR12, -Ge-, -Sn-, -O-, -S-, =SO, =SO2, =NR12, =CO, =PR12 or =P(O)R12;  R12  =  H, halo, 1-10C (fluoro)alkyl, 6-10C (fluoro)aryl, 1-10C alkoxy, 2-10C alkenyl, 7-40 C arylalkyl, alkylaryl or arylalkenyl or two R12 groups together with the atoms they are bonded to form a ring;  M1  =  Si, Ge or Sn;  m  =  0-3;  T  =  formula (10)-(12);  T'  =  formula (13)-(15);  R13, R13', R14, R14'  =  H, halo, 1-20C alkyl, 3-8 membered cycloalkyl optionally substituted by 1-10C alkyl, 6-15C aryl, (1-10C)alkyl-(6-20C)aryl, -OR10, -SR10, -N(R10)2, -P(R10)2 or Si(R9)3;  Z'  =  -(Q(R15)(R16))q-;  Q  =  Si, Ge, Sn or C;  R15, R16  =  1-10C alkyl, 3-10C cycloalkyl or 6-15C aryl;  q  =  1-4;  R17-R20, R17'-R20'  =  1-20C alkyl, 3-8 membered cycloalkyl optionally substituted by 1-10C alkyl, 6-15C aryl or alkylaryl whereby neighboring groups optionally form 4-15C cyclic groups or Si(R11)3;  M2  =  alkali- or alkaline earth metal cation; and p  =  1 or 2. An Independent claim is also included for racemic metallocene complexes of formula (3) where the  olefinic bonds of groups (10-(15) are hydrogenated.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E401391-T1: [Translated] NEW STEROID-ACTIVATED NUCLEAR RECEPTORS AND USES THEREOF

A novel nuclear receptor, termed the steroid and xenobiotic receptor (SXR), a broad-specificity sensing receptor that is a novel branch of the nuclear receptor superfamily, has been discovered. SXR forms a heterodimer with RXR that can bind to and induce transcription from response elements present in steroid-inducible cytochrome P450 genes in response to hundreds of natural and synthetic compounds with biological activity, including therapeutic steroids as well as dietary steroids and lipids. Instead of hundreds of receptors, one for each inducing compound, the invention SXR receptors monitor aggregate levels of inducers to trigger production of metabolizing enzymes in a coordinated metabolic pathway. Agonists and antagonists of SXR are administered to subjects to achieve a variety of therapeutic goals dependent upon modulating metabolism of one or more endogenous steroids or xenobiotics to establish homeostasis. An assay is provided for identifying steroid drugs that are likely to cause drug interaction if administered to a subject in therapeutic amounts.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Workforce Part 1 — The Workforce Development Framework

This Child Welfare Information Gateway Podcast is available on Apple Podcasts
  
  

, GooglePlay
  
  

, Spotify
  
  

, Stitcher
  
  

, SoundCloud
  
  

, and the Child Welfare Information Gateway
  
  

 website. Subscribe to receive new episodes as they are released.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, maker, podcast, policy, social
Organization: U.S. Department of Health & Human Services
Compound 530016: 3,4-Dimethoxybenzaldehyde o-methyloxime

Chemical compound data from PubChem database. IUPAC Name: 1-(3,4-dimethoxyphenyl)-N-methoxymethanimine. Molecular Formula: C10H13NO3. Molecular Weight: 195.21. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Resources for Populations Served by ACF Programs

In support of ACF’s mission and strategic plan, ACF has developed a set of materials intended for specific subgroups of program participants, prospective participants, and their communities to help them understand the array of programs and resources that may be able to assist them. These one- to two-page overviews are available below.

Who should use these materials?

Why use these materials?

Many families, individuals, and communities may not know about the full range of services and resources that are available to and could benefit them. These materials can help them find and access helpful supports tailored to their particular situation.

How should these materials be shared?

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: family, guidance, policy, scope, social
Organization: U.S. Department of Health & Human Services