AndreaBozzo/ceres-open-data-index huggingface dataset:
Open tension free repair of inguinal hernias; the Lichtenstein technique

Background
          Recurrences have been a significant problem following hernia repair. Prosthetic materials have been increasingly used in hernia repair to prevent recurrences. Their use has been associated with several advantages, such as less postoperative pain, rapid recovery, low recurrence rates.
        
        
          Methods
          In this retrospective study, 540 tension-free inguinal hernia repairs were performed between August 1994 and December 1999 in 510 patients, using a polypropylene mesh (Lichtenstein technique). The main outcome measure was early and late morbidity and especially recurrence.
        
        
          Results
          Inguinal hernia was indirect in 55 % of cases (297 patients), direct in 30 % (162 patients) and of the pantaloon (mixed) type in 15 % (81 patients). Mean patient age was 53.7 years (range, 18 – 85). Follow-up was completed in 407 patients (80 %) by clinical examination or phone call. The median follow-up period was 3.8 years (range, 1 – 6 years). Seroma and hematoma formation requiring drainage was observed in 6 and 2 patients, respectively, while transient testicular swelling occurred in 5 patients. We have not observed acute infection or abscess formation related to the presence of the foreign body (mesh). In two patients, however, a delayed rejection of the mesh occurred 10 months and 4 years following surgery. There was one recurrence of the hernia (in one of these patients with late mesh rejection) (recurrence rate = 0.2 %). Postoperative neuralgia was observed in 5 patients (1 %).
        
        
          Conclusion
          Lichtenstein tension-free mesh inguinal hernia repair is a simple, safe, comfortable, effective method, with extremely low early and late morbidity and remarkably low recurrence rate and therefore it is our preferred method for hernia repair since 1994.

Tags: hernia-repair, inguinal-hernia, lichtenstein-technique, nih, surgical-outcomes
Organization: U.S. Department of Health & Human Services
P-Value Tables

State estimates for these years are no longer available due to methodological concerns with combining 2019 and 2020 data. We apologize for any inconvenience or confusion this may causeBecause of the COVID-19 pandemic, most respondents answered the survey via the web in Quarter 4 of 2020, even though all responses in Quarter 1 were from in-person interviews. It is known that people may respond to the survey differently while taking it online, thus introducing what is called a mode effect.When the state estimates were released, it was assumed that the mode effect was similar for different groups of people. However, later analyses have shown that this assumption should not be made. Because of these analyses, along with concerns about the rapid societal changes in 2020, it was determined that averages across the two years could be misleading.For more detail on this decision, see the 2019-2020state data page.

Tags: data-quality, estimate-reliability, mode-effects, samhsa, survey-methodology
Organization: U.S. Department of Health & Human Services
National Directory of Drug and Alcohol Abuse Treatment Facilities 2010

The National Directory of Drug and Alcohol Abuse Treatment Programs 2010 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 2009 National Survey of Substance Abuse Treatment Services (N-SSATS). The information about each facility that appears in this directory was provided by that facility in response to the 2009 N-SSATS. The Substance Abuse and Mental Health Services Administration (SAMHSA) conducts the N-SSATS annually.

Tags: alcohol-abuse-treatment, n-ssats, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Maryland, 2014

This is a behavioral health report for the state of Maryland. It uses the National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use, youth mental health and treatment, adult mental health and treatment, substance use, and substance use treatment for the years 2009 to 2013.

Tags: maryland-behavioral-health, mental-health-maryland, samhsa, substance-use-trends, youth-mental-health
Organization: U.S. Department of Health & Human Services
2012 Uniform Reporting System (URS) Tables for Massachusetts

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, mental-health-services, outcome-measures, samhsa, utilization-data
Organization: U.S. Department of Health & Human Services
2014 CMHS Uniform Reporting System (URS) Table for Guam

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Guam. The URS territories reporting system is collected annually to support the Community Mental Health Services Block Grant program. Territories Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: guam, mental-health-services, outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Publications Using SAMHSA DataEstimated totals and 95% confidence intervals (in thousands) for persons aged 12 or older, 12 to 17, 18 to 25, 26 or older, and 18 or older; also for persons 12 to 20 for two alcohol measures

This report presents estimates for measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: age-groups, mental-health, national-survey, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
2011 CMHS Uniform Reporting System (URS) Output Tables for New Jersey

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, noms-measures, samhsa, utilization-measures
Organization: U.S. Department of Health & Human Services
Treatment Episode Data Set (TEDS) 2004 Discharges from Substance Abuse Treatment Services

This report presents results from the Treatment Episode Data Set (TEDS) for clients discharged from substance abuse treatment in 2004. The report provides information on treatment completion, length of stay in treatment, and demographic and substance abuse characteristics of approximately 1,000,000 people discharged from alcohol or drug treatment in facilities that report to individual state administrative data systems.

Tags: alcohol-drug-treatment, samhsa, substance-abuse-treatment, treatment-episode-data, treatment-outcomes
Organization: U.S. Department of Health & Human Services
Regional Partnership Grants National Cross-Site Evaluation (RPG-5 and RPG-6)

To address the far-reaching consequences of adult substance use disorders on families and children, Congress authorized competitive grants to support partnerships among child welfare, substance abuse treatment, and related organizations. Children’s Bureau (CB) within the Administration for Children and Families, Administration on Children, Youth, and Families at the U.S. Department of Health and Human Services established the Regional Partnership Grant (RPG) program, and awarded a total of 56 5-year grants across 4 cohorts to implement programs to meet the needs of this target population.

Investigators: Angela Dangelo, Ph.D.
Mathematica Washington, DC

Juliette Henke, MPP
Mathematica Washington, DC

Yange Xue, Ph.D.
Mathematica Washington, DC

Betsy Keating, MPP
Mathematica Washington, DC

Claire Smither Wulsin, MPP
Mathematica Washington, DC

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
Treatment Episode Data Set (TEDS) 1993-2003 National Admissions to Substance Abuse Treatment Services

This report presents results from the Treatment Episode Data Set (TEDS) for 2003 and trend data for 1993-2003. The report provides information on the demographic and substance abuse characteristics of the 1.8 million people admitted to treatment for abuse of alcohol and drugs in 2003 to facilities that report to individual state administrative data systems.

Tags: alcohol-drug-abuse, samhsa, substance-abuse-treatment, teds-admissions, treatment-episodes
Organization: U.S. Department of Health & Human Services
2011 CMHS Uniform Reporting System (URS) Output Tables for Iowa

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, iowa, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Refugee Resettlement Program Estimates: CMA ORR-1

For quarterly grants for cash assistance, medical assistance and related administrative costs, including assistance and services to unaccompanied minors (“CMA grants”), a State must submit to the Director, or designee, yearly estimates for reimbursable costs for the fiscal year, identified by type of expense, and a justification statement in support of the estimates no later than 45 days prior to the beginning of the fiscal year in accordance with guidelines prescribed by the Director.

<b>Units of Response: </b>States

<b>Type of Data: </b>Financial

<b>Tribal Data: </b>No

<b>COVID-19 Data: </b>No

<b>Periodicity: </b>Unavailable

<b>SORN: </b>Not Applicable

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Unavailable

<b>Equity Indicators: </b>Not Applicable

<b>Granularity: </b>State

<b>Spatial: </b>United States

<b>Geocoding: </b>Unavailable

Tags: refugee-resettlement
Organization: U.S. Department of Health & Human Services
Hepatitis C virus whole genome position weight matrix and robust primer design

Background
          The high degree of sequence heterogeneity found in Hepatitis C virus (HCV) isolates, makes robust nucleic acid-based assays difficult to generate. Polymerase chain reaction based techniques, require efficient and specific sequence recognition. Generation of robust primers capable of recognizing a wide range of isolates is a difficult task.
        
        
          Results
          A position weight matrix (PWM) and a consensus sequence were built for each region of HCV and subsequently assembled into a whole genome consensus sequence and PWM. For each of the 10 regions, the number of occurrences of each base at a given position was compiled. These counts were converted to frequencies that were used to calculate log odds scores. Using over 100 complete and 14,000 partial HCV genomes from GenBank, a consensus HCV genome sequence was generated along with a PWM reflecting heterogeneity at each position. The PWM was used to identify the most conserved regions for primer design.
        
        
          Conclusions
          This approach allows rapid identification of conserved regions for robust primer design and is broadly applicable to sets of genomes with all levels of genetic heterogeneity.

Tags: genome-sequencing, hepatitis-c, nih, position-weight-matrix, primer-design
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Idaho, 2014

This is a behavioral health report for the state of Idaho. It uses the National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use, youth mental health and treatment, adult mental health and treatment, substance use, and substance use treatment for the years 2009 to 2013.

Tags: idaho-behavioral-health, mental-health-services, samhsa, substance-use-trends, youth-mental-health
Organization: U.S. Department of Health & Human Services
Primary renal carcinoid natural history of the disease for ten years: case report

Background
          Primary renal carcinoid is extremely rare and there are few reports on the natural history of the disease.
        
        
          Case presentation
          A 68-year-old male with a right renal mass who lost to follow-up for ten years has been presented. His only complaint was a mild flank pain. Upon admission to the hospital for his renal mass, he underwent a right radical nephrectomy and pathological examination revealed the diagnosis of primary renal carcinoid.
        
        
          Conclusions
          In light of the presented case, primary renal carcinoma may have a prolonged natural history with no distant metastasis and any change in the quality of life of the patient.

Tags: case-report, kidney-cancer, nih, radical-nephrectomy, renal-carcinoid
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Montana

This is the 2020 Uniform Reporting System (URS) Output Tables for Montana. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, outcome-measures, samhsa, state-mental-health
Organization: U.S. Department of Health & Human Services
Compound 525285: N'-Propyl-N,N-dimethyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-propylethanimidamide. Molecular Formula: C7H16N2. Molecular Weight: 128.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Prescription drug monitoring programs, nonmedical use of prescription drugs, and heroin use: Evidence from the National Survey of Drug Use and Health.

This study examines the impact of prescription drug monitoring programs on nonmedical use of prescription drugs and heroin. It was funded using FY16 ASC dollars.Prescription drug monitoring programs, nonmedical use of prescription drugs, and heroin use: Evidence from the National Survey of Drug Use and Health.(link is external)

Tags: heroin-use, nonmedical-drug-use, nsduh-data, prescription-drug-monitoring, samhsa
Organization: U.S. Department of Health & Human Services
Bone mineral density and the subsequent risk of cancer in the NHANES I follow-up cohort

Backgroud
          Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast cancer risk in three cohorts. In order to assess further BMD as a predictor of estrogen related cancer risk, the association of BMD with colorectal and corpus uteri cancer was investigated in the NHANES I Epidemiologic Followup Study (NHEFS) cohort along with breast cancer and prostate cancer.
        
        
          Methods
          Participants were members of the NHEFS cohort who had BMD measurement in 1974–1975. Age, race, and BMI adjusted rate ratios and 95% confidence intervals were calculated for incidence of cancers of the corpus uterus, breast, colorectum, prostate, and of osteoporosis and hip fracture related to baseline BMD.
        
        
          Results
          Data were available for 6046 individuals. One hundred cases of breast cancer, 94 prostate cancers, 115 colorectal cancers, 29 uterine cancers, 110 cases of hip fracture and 103 cases of osteoporosis were reported between 1974 and 1993. Hip fracture and osteoporosis were both significantly inversely associated with BMD. Uterine cancer was positively associated (p = 0.005, test for linear trend) and colorectal cancer negatively associated (p = 0.03) with BMD. No association was found between elevated BMD and incidence of breast cancer (p = 0.74) or prostate cancer (p = 0.37) in the overall cohort, although a weak association was seen between BMD and subsequent breast cancer incidence when BMD was measured in post-menopausal women (p = 0.04).
        
        
          Conclusion
          The findings related to cancers of the uterus and colorectum as well as the weak association of BMD with breast cancer strengthen the use of BMD as a marker of estrogen exposure and cancer risk.

Tags: bone-mineral-density, cancer-risk, estrogen-related-cancers, nhanes-i-follow-up, nih
Organization: U.S. Department of Health & Human Services
Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation

Background
          Vascular endothelial growth factor (VEGF) mRNA levels increase in rat skeletal muscle after a single bout of acute exercise. We assessed regional differences in VEGF165 mRNA levels in rat gastrocnemius muscle using in situ hybridization after inducing upregulation of VEGF by treadmill running (1 hr) or electrical stimulation (1 hr). Muscle functional regions were defined as oxidative (primarily oxidative fibers, I and IIa), or glycolytic (entirely IIb or IId/x fibers). Functional regions were visualized on muscle cross sections that were matched in series to slides processed through in situ hybridization with a VEGF165 probe. A greater upregulation in oxidative regions was hypothesized.
        
        
          Results
          Total muscle VEGF mRNA (via Northern blot) was upregulated 3.5-fold with both exercise and with electrical stimulation (P = 0.015). Quantitative densitometry of the VEGF mRNA signal via in situ hybridization reveals significant regional differences (P ≤ 0.01) and protocol differences (treadmill, electrical stimulation, and control, P ≤ 0.05). Mean VEGF mRNA signal was higher in the oxidative region in both treadmill run (~7%, N = 4 muscles, P ≤ 0.05) and electrically stimulated muscles (~60%, N = 4, P ≤ 0.05). These regional differences were not significantly different from control muscle (non-exercised, non-stimulated, N = 2 muscles), although nearly so for electrically stimulated muscle (P = 0.056).
        
        
          Conclusions
          Moderately higher VEGF mRNA signal in oxidative muscle regions is consistent with regional differences in capillary density. However, it is not possible to determine if the VEGF mRNA signal difference is important in either the maintenance of regional capillarity differences or exercise induced angiogenesis.

Tags: exercise-stimulation, gastrocnemius-muscle, muscle-fiber-types, nih, vegf-mrna
Organization: U.S. Department of Health & Human Services
Research Article: BMC Biotechnology

Background
          The suitability of the strain Rhodococcus erythropolis ATCC 25544 grown in a two-liter fermentor as a source of cholesterol oxidase has been investigated. The strain produces both cell-linked and extracellular cholesterol oxidase in a high amount, that can be extracted, purified and concentrated by using the detergent Triton X-114.
        
        
          Results
          A spray-dry method of preparation of the enzyme inducer cholesterol in Tween 20 was found to be superior in both convenience and enzyme synthesis yield to one of heat-mixing. Both were similar as far as biomass yield is concerned. Cell-linked cholesterol oxidase was extracted with Triton X-114, and this detergent was also used for purification and concentration, following temperature-induced detergent phase separation. Triton X-114 was utilized to purify and to concentrate the cell-linked and the extracellular enzyme. Cholesterol oxidase was found mainly in the resulting detergent-rich phase. When Triton X-114 concentration was set to 6% w/v the extracellular, but not the cell-extracted enzyme, underwent a 3.4-fold activation after the phase separation process. This result is interpreted in the light of interconvertible forms of the enzyme that do not seem to be in equilibrium. Fermentation yielded 360 U/ml (672 U/ml after activation), 36% of which was extracellular (65% after activation). The Triton X-114 phase separation step yielded 11.6-fold purification and 20.3-fold concentration.
        
        
          Conclusions
          The results of this work may make attractive and cost-effective the implementation of this bacterial strain and this detergent in a purification-based industrial production scheme of commercial cholesterol oxidase.

Tags: cholesterol-oxidase, enzyme-production, nih, rhodococcus-erythropolis
Organization: U.S. Department of Health & Human Services
Comparative risk judgements for oral health hazards among Norwegian adults: a cross sectional study

Background
          This study identified optimistic biases in health and oral health hazards, and explored whether comparative risk judgements for oral health hazards vary systematically with socio-economic characteristics and self-reported risk experience.
        
        
          Methods
          A simple random sample of 1,190 residents born in 1972 was drawn from the population resident in three counties of Norway. A total of 735 adults (51% women) completed postal questionnaires at home.
        
        
          Results
          Mean ratings of comparative risk judgements differed significantly (p < 0.001) from the mid point of the scales. T-values ranged from -13.1 and -12.1 for the perceived risk of being divorced and loosing all teeth to -8.2 and -7.8 (p < 0.001) for having gum disease and toothdecay. Multivariate analyses using General Linear Models, GLM, revealed gender differences in comparative risk judgements for gum disease, whereas social position varied systematically with risk judgements for tooth decay, gum disease and air pollution. The odds ratios for being comparatively optimistic with respect to having gum disease were 2.9, 1.9, 1.8 and 1.5 if being satisfied with dentition, having a favourable view of health situation, and having high and low involvement with health enhancing and health detrimental behaviour, respectively.
        
        
          Conclusion
          Optimism in comparative judgements for health and oral health hazards was evident in young Norwegian adults. When judging their comparative susceptibility for oral health hazards, they consider personal health situation and risk behaviour experience.

Tags: dental-caries, nih, norway, oral-health, risk-perception
Organization: U.S. Department of Health & Human Services