AndreaBozzo/ceres-open-data-index huggingface dataset:
Radiation-induced bystander effects and gene expression in cells deficient for RAD9

Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation exposure to humans. The mechanism of radiation response includes inter-cellular signaling and intra-cellular communication by which the bystander signal is propagated. Methods: We measured the bystander response to 1Gy a-particle radiation in Mrad9-/- mouse stem cells and H1299shRAD9 cells using chromosomal aberration and micronucleus formation as DNA damage endpoints. In the H1299 model we used whole genome microarray analyses to profile the transcriptome of irradiated and bystander cells. Results: We investigated the role of RAD9 in the bystander response and showed that depletion or mutation of RAD9 had an effect of increasing chromosomal structural damage as well as micronucleus formation in bystander cells. The enhancement of the damage effect correlated strongly with a transcriptomic response in critical pathways. RAD9 depletion affected many pathways in the cell including the UV-MAPK pathway involving p38MAPK members STAT1 and PARP1 at the mRNA levels. There was an overall reduction of RNA biogenesis of gene members of this pathway suggesting that perhaps these signaling pathways do not function optimally after RAD9 depletion. Using network analysis we found there may be differential activation of transcriptional regulators between the irradiated and bystander cells involving the SP1 and NUPR1 transcription factors. Network analysis also suggested that HIF1a (Hypoxia induced factor 1a) activation could be a negative predictor of the bystander effect and perhaps that local hypoxic stress observed by cells that are directly exposed to radiation may predict whether or not they will elicit a bystander response. Gene expression in H1299 cells was measured at 4 hours after exposure to 1 Gy a-particles. There were two groups based on RAD9 status RAD9 normal and RAD9 depleted by siRNA. In each of these groups sham irradiated direct irradiated cells for positive bystanders positive bystanders direct irradiated cells for negative bystanders and negative bystanders; were identified based on micronucleus responses. Five biological replicates were analyzed for each experimental group.

Tags: array-scanning-protocol, bystander, dose, growth-protocol, hybridization-protocol, ionizing-radiation, labelling-protocol, normalization-data-transformation-protocol, nucleic-acid-extraction-protocol, p-gse55869-1, p-gse55869-2, p-gse55869-3, p-gse55869-4, p-gse55869-5, p-gse55869-6, p-gse55869-7, rad9-status, sample-treatment-protocol
Organization: National Aeronautics and Space Administration
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [parabolic]

We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential gravity-regulated genes and adaptation processes. Overall design: Human myelomonocytic U937 cells were exposed to altered gravity during a parabolic flight.

Tags: altered-gravity, data-collection, growth, labeling, normalization-data-transformation, nucleic-acid-hybridization, rna-extraction, sample-collection, treatment
Organization: National Aeronautics and Space Administration
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology

Comparitive gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in the specially designed Mouse Drawer System in weightlessness aboard the International Space Station. Three wild-type mice (WT) and three transgenic mice overexpressing the osteogneic factor PTN/OSF1 under the control of the human bone specific ostecalcin promoter (Tg) were used in the experiment. During the 3-month stay on the ISS 3 mice unfortunately died leaving 2 Tg and 1 WT. MDS tissue sharing program allowed several teams to study various tissues from these mice. Our aim was to investigate the effect of such a long period of microgravity on skin physiology by morphological biochemical and genomewide analyses by comparison to similar mice on ground. Gene expression in the skin of 3 space mice and of 3 ground mice was analyzed by microarray. As this unique experiment performed on 3 mice limits the power of statistical analyis as the transgene PTN/OSF1 was not overexpressed in skin and as a pair wise Pearson  s correlation rates between the individual levels of expressed transcripts in the WT and the Tg mice were not significantly different from each other in one experimental group (space or ground) data from the 3 mice were combined to compare results from the space an ground groups.

Tags: array-scanning-and-feature-extraction-protocol, genotype, nucleic-acid-extraction-protocol, nucleic-acid-hybridization-to-array-protocol, nucleic-acid-labeling-protocol, p-mtab-40820, p-mtab-40821, p-mtab-40822, p-mtab-40823, p-mtab-40824, spaceflight, treatment-protocol
Organization: National Aeronautics and Space Administration
OrbView-2 SeaWiFS 4B Global Binned Garver-Siegel-Maritorena Model (GSM) Data, version R2022.0

The SeaWiFS instrument was launched by Orbital Sciences Corporation on the OrbView-2 (a.k.a. SeaStar) satellite in August 1997, and collected data from September 1997 until the end of mission in December 2010. SeaWiFS had 8 spectral bands from 412 to 865 nm. It collected global data at 4 km resolution, and local data (limited onboard storage and direct broadcast) at 1 km. The mission and sensor were optimized for ocean color measurements, with a local noon (descending) equator crossing time orbit, fore-and-aft tilt capability, full dynamic range, and low polarization sensitivity.

Tags: earth-science, ocean-optics, oceans
Organization: National Aeronautics and Space Administration
BeXRB Monitor Data

This is a monitor using data from Swift/BAT, MAXI and Fermi/GBM instruments. 
Click on the table header to change the sorting behaviour. 
Color code for the probability: (rising flux , no change, decreasing flux)
The average flux is calculated as the average of the last 3 days of data, without taking the errors into account. The fermi flux is not given in mCrab. 
Please note that the accuracy of the probabilities is limited by the accuracy of the data used.
Release of Friday, the 17th of October 2014

Last updated at 14:04:07 UT

Created as an ESAC trainee project by Eva Laplace. 
Supervisors: Peter Kretschmar, Emilio Salazar and Miguel Arregui. 
Contact: peter.kretschmar@esa.int

Tags: spaceapps
Organization: National Aeronautics and Space Administration
Woman skeletal muscle transcriptome with bed rest and countermeasures.

Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to loss of muscle mass and structural disorders is necessary for the definition of efficient clinical and spaceflight countermeasures. We investigated the effects of long-term bed rest on transcriptome of soleus (SOL) and vastus lateralis (VL) muscles in healthy women (BRC group n=8) and the potential beneficial impact of protein supplementation (BRN group n=8) and of a combined resistance and aerobic training (BRE group n=8). Gene expression profiles were obtained using an in-house made microarray containing 6681 muscles-relevant genes. A two-class statistical analysis was applied on the 2103 genes with consolidated expression. We identified 472 and 207 modified genes respectively for SOL and VL in BRC group. Further clustering approaches identifying relevant biological mechanisms or pathways underlined five main subclusters. Three are composed almost of upregulated genes involved mainly in nucleic acid and protein metabolism and two composed almost of downregulated genes involved in energy metabolism. Exercise countermeasure demonstrated a drastic compensatory effect decreasing the number of differentially-expressed genes by 89 and 96% in SOL and VL. In contrast nutrition countermeasure had a moderate effect and decreased the number of differentially-expressed genes by 40 and 25% in SOL and VL. Our results allowed reporting a systematic global and comprehensive view of long-term woman muscle atrophy and brought new lights and insights for space environment and for women who undergo a long-term clinical bed rest. Biological samples were collected from Pre- and Post- bed rest (BR) soleus and vastus lateralis biopsies of each subject from the three groups (bed rest only: BRC; Exercise: BRE; Nutrition: BRN). six technical replicate values (2 duplicate hybridizations a et b to chips with triplicate spots xxx) were obtained for each skeletal muscle sample. Thus for each subject 12 expression measurements (6 before BR and 6 after BR) were obtained for each muscle.

Tags: bed-rest, bioassay_data_transformation, exercise, feature_extraction, hybridization, image_aquisition, labeling, nucleic_acid_extraction, nutrition, p-gse14798-1, p-gse14798-2, p-gse14798-3, p-gse14798-4, p-gse14798-5, p-gse14798-6, tissue
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P RSI 1/2/3
                                     PRELANDING 0203 V1.0

This is a Rosetta Radio Science data set, collected during the PRELANDING phase 2014-01-21 to 2014-11-18. It is a Global Gravity measurement at the comet 67P and covers the time 2014-08-13T10:00:55.000 to 2014-08-13T13:36:58.000.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
Aqua MODIS Global Binned Chlorophyll (CHL) - NRT Data, version R2022.0

The Ocean Biology DAAC produces near real-time (quicklook) products using the best-available combination of ancillary data from meteorological and ozone data. As such, the inputs and the calibration used are less than optimal. Quicklook products provide a snapshot of the data during a short time period within a single orbit.

Tags: earth-science, national-geospatial-data-asset, ngda, ocean-chemistry, ocean-optics, oceans
Organization: National Aeronautics and Space Administration
USGS Global Forest Observations Initiative (GFOI) Guyana

The Global Forest Observations Initiative (GFOI) is an initiative of the inter-governmental Group on Earth Observations (GEO) that aims to:

foster the sustained availability of observations for national forest monitoring systems; support governments that are establishing national systems by providing a platform for coordinating observations, providing assistance and guidance on utilizing observations, developing accepted methods and protocols, and promoting ongoing research and development; and work with national governments that report into international forest assessments (such as the global Forest Resources Assessment (FRA) of the Food and Agriculture Organization, FAO) and the national greenhouse gas inventories reported to the UN Framework Convention on Climate Change (UNFCCC) using methods of the Intergovernmental Panel on Climate Change (IPCC).

Tags: agriculture, biosphere, earth-science, forest-science, habitat-conversion-fragmentation, human-dimensions, terrestrial-ecosystems, vegetation
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P OSIWAC 4 EXT2-MTP029 RDR-REFLECT V1.0

This CODMAC level 4 data set contains radiometric calibrated and geometric distortion corrected (resampled) image data in reflectance units (normalized and thus without unit), acquired by the OSIRIS Wide Angle Camera on the Rosetta spacecraft during the ROSETTA EXTENSION 2 mission phase, covering the period from 2016-05-03T23:25:00.000 to 2016-05-31T23:24:59.000. The prime target is comet 67P/Churyumov-Gerasimenko 1 (1969 R1). This version V1.0 is the first version of this dataset: Lien corrected dataset after October 2018 PSA/PDS external peer review.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER X SREM 5 CRUISE 3
    V1.0

This data set contains derived electron and proton flux energies in MeV from the Standard Radiation Environment Monitor (SREM) instrument on the Rosetta spacecraft.  These are CODMAC Level 5 derived data, and measure the radiation in the spacecraft environment during the CRUISE 3 mission phase.

Tags: calibration, international-rosetta-mission
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P OSIWAC 2 ESC1-MTP011 EDR V3.0

This CODMAC level 2 data set contains uncalibrated image data in DN unit, acquired by the OSIRIS Wide Angle Camera on the Rosetta spacecraft during the COMET ESCORT 1 mission phase, covering the period from 2014-12-19T23:25:00.000 to 2015-01-13T23:24:59.000. The prime target is comet 67P/Churyumov-Gerasimenko 1 (1969 R1). This version V3.0 supersedes previous deliveries of the same dataset with the following changes since the last version: Lien corrected dataset after the July and October 2018 PSA/PDS external peer reviews. Updated documentation and ancillary files, added document on bandpass filter. Updated SCIENCE_USER_GUIDE_V03.PDF to include one section about FAQ and one section about image data quality. Added shutter backtravel and readout issues to image quality map. Updated DATA_QUALITY_ID keyword in image header. Improved handling of images with missing packets. Included FITs files. Browse products changed to the same size as the original image.

Tags: 16-cyg-b, 67p-churyumov-gerasimenko-1-1969-r1, bias, dark, international-rosetta-mission, vega
Organization: National Aeronautics and Space Administration
Table 18. Alcohol Dependence in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year alcohol dependence by those aged 12 or older by State and substate regions.

Tags: adolescent-alcohol-use, alcohol-dependence, nsduh, samhsa, substate-data
Organization: U.S. Department of Health & Human Services
ROSETTA-ORBITER 67P NAVCAM 2 COMET ESCORT 2 MTP016 V1.0

This dataset contains ROSETTA NAVCAM RAW DATA of the Escort Phase 2 from 5th May 2015 to 2nd Jun 2015 when at the vicinity of target 67P/CG.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P OSIWAC 4 ESC2-MTP014 RDR-INF-REFL V1.0

This CODMAC level 4 data set contains solar stray-light corrected, in-field stray-light corrected,  radiometric calibrated and geometric distortion corrected  (resampled) image data in reflectance units (normalized  and thus without unit),  acquired by the OSIRIS Wide Angle Camera on the Rosetta spacecraft  during the COMET ESCORT 2 mission phase, covering the period  from 2015-03-10T23:25:00.000 to 2015-04-08T11:24:59.000. The prime target is comet 67P/Churyumov-Gerasimenko 1 (1969 R1). This version V1.0 is the first version of this dataset: Lien corrected dataset after September 2019 PSA/PDS external peer review.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
USGS Group on Earth Observations (GEO) Global Agricultural Monitoring (GLAM) Ukraine

The objective of GEO is to fulfill a vision of a world where decisions and actions are informed by coordinated, comprehensive and sustained Earth Observation (EO). This is being pursued mainly through the added value of coordinating existing institutions, organized communities, space agencies, insitu monitoring agencies, scientific institutions, research centres, universities, modelling centres, technology developers and other groups that deal with one or more aspects of EO. To reach this overarching goal, GEO focuses on capacity development in three dimensions: infrastructure, individuals and institutions. In the field of agriculture, the general goal is to promote the utilization of Earth observations for advancing sustainable agriculture, aquaculture and fisheries. Key issues include early warning, risk assessment, food security, market efficiency and combating desertification. 

(Source: http://www.research-europe.com/index.php/2011/08/joao-soares-secretariat-expert-for-agriculture-group-on-earth-observations/)

Tags: agricultural-plant-science, agriculture, earth-science, food-science, plant-commodities
Organization: National Aeronautics and Space Administration
U.S. Climate Risk Projections by County, 2040-2049

The U.S. Climate Risk Projections by County, 2040-2049 data set contains a projection for 2040-2049 risk for the entire contiguous U.S. at the county level with a novel climate risk index integrating multiple hazards, exposures and vulnerabilities. Multiple hazards such as weather and climate are characterized as a frequency of heat wave, cold spells, drought, and heavy precipitation events along with anomalies of temperature and precipitation using high resolution (4 km) downscaled climate projections. Exposure is characterized by projections of population, infrastructure, and built surfaces prone to multiple hazards including sea level rise and storm surges. Vulnerability is characterized by projections of demographic groups most sensitive to climate hazards. This approach can guide planners in targeting counties at most risk and where adaptation strategies to reduce exposure or protect vulnerable populations might be best applied.

Tags: earth-science, human-dimensions, natural-hazards, snow-ice, socioeconomics, terrestrial-hydrosphere
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P RSI 1/2/3
                                     PRELANDING 0250 V1.0

This is a Rosetta Radio Science data set, collected during the PRELANDING phase 2014-01-21 to 2014-11-18. It is a Global Gravity measurement at the comet 67P and covers the time 2014-08-27T23:34:15.000 to 2014-08-28T01:02:29.000.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
SMAPVEX12 Land Cover Classification Map V001

This data set consists of land cover classification data derived from satellite imagery as part of the Soil Moisture Active Passive Validation Experiment 2012 (SMAPVEX12). Images from the RADARSAT-2, Système Pour l'Observation de la Terre (SPOT-4), and DMC International Imaging Ltd (DMCii) of the study area were retrieved for the summer of 2012. The land use classification image provides information about vegetation present in the study area at a resolution of 20 meters.

Tags: earth-science, land-surface, land-use-land-cover
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P OSINAC 3 PRL-MTP008 RDR V3.0

This CODMAC level 3 data set contains radiometric calibrated image data in W/m^2/sr/nm, acquired by the OSIRIS Narrow Angle Camera on the Rosetta spacecraft during the PRELANDING mission phase, covering the period from 2014-09-23T10:00:00.000 to 2014-10-24T09:59:59.000. The prime target is comet 67P/Churyumov-Gerasimenko 1 (1969 R1). This version V3.0 supersedes previous deliveries of the same dataset with the following changes since the last version: Lien corrected dataset after the July and October 2018 PSA/PDS external peer reviews. Updated documentation and ancillary files, added document on bandpass filter. Updated SCIENCE_USER_GUIDE_V03.PDF to include one section about FAQ and one section about image data quality. Added shutter backtravel and readout issues to image quality map. Updated DATA_QUALITY_ID keyword in image header. Improved handling of images with missing packets. Included FITs files. Browse products changed to the same size as the original image.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
Astronomy Picture of the Day API

This endpoint structures the APOD imagery and associated metadata so that it can be repurposed for other applications. In addition, if the concept_tags parameter is set to True, then keywords derived from the image explanation are returned. These keywords could be used as auto-generated hashtags for twitter or instagram feeds; but generally help with discoverability of relevant imagery.

Tags: api, apod, sharing-share, social-media
Organization: National Aeronautics and Space Administration
Nimbus Image Dissector Camera System Visible Imagery L1, HDF5 V001

The Nimbus Image Dissector Camera System Visible Imagery L1, HDF5 (NmIDCS1H) data set consists of black-and-white images captured by the Image Dissector Camera Systems (IDCSs) onboard the Nimbus 3 and Nimbus 4 satellites. Data are provided as HDF5-formatted files. Browse images are also available.

Tags: earth-science, spectral-engineering, visible-wavelengths
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P RSI 1/2/3
                                     ROSETTA EXTENSION 1 1395 V1.0

This is a Rosetta Radio Science data set, collected during the ROSETTA EXTENSION 1 phase 2016-01-01 to 2016-04-05. It is a Global Gravity measurement at the comet 67P and covers the time 2016-02-03T09:07:40.000 to 2016-02-03T12:49:40.500.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration
Activity modeling under uncertainty by trace of objects in smart homes

A typical resident of a smart home can be an Alzheimer patient that forgets sometimes to complete the activities that he begins. The key point to assist the smart home resident is to model the activities and discover correct realization patterns of activities. To accomplish this task, we apply sensors to provide primary data about realization patterns of actions, operations, plans, goals and generally any objective that the smart home resident may desire to do. In the consequence, by applying fuzzy clustering techniques, we are able to mine sensor data to retrieve the realization patterns of activities, and so the prediction patterns of intentions are recognizable. Comparing the realization patterns with prediction patterns of activities, we would be able to predict the intention of the resident about the activity that the resident considers to realize. In this way, we would be able to provide hypotheses about the resident goals and his possible goal achievement’s defects. Spatiotemporal aspects of daily activities such as movement of objects are surveyed to discover the patterns of activities realized by the smart homes residents. In this research, uncertainty is considered as a property of activity recognition.

Tags: ames, dashlink, nasa
Organization: National Aeronautics and Space Administration
VEGA1 TV SYSTEM IMAGES V1.0

For the TV SYSTEM, 95 images were sent as a 7-d FITS file with little information in the FITS headers. In addition, to the size of the image (NAXIS1 and NAXIS2), the values for NAXIS3 and NAXIS4 were labeled 'TIME' interpreted as exposure time in seconds. The following procedure was used to convert NAXIS3 information:

Tags: halley, vega-1
Organization: National Aeronautics and Space Administration
ROSETTA-ORBITER 67P RSI 1/2/3
                                     COMET ESCORT 1 0555 V1.0

This is a Rosetta Radio Science data set, collected during the COMET ESCORT 1 phase 2014-11-20 to 2015-03-10. It is a Global Gravity measurement at the comet 67P and covers the time 2015-01-29T23:09:05.000 to 2015-01-30T11:01:34.000.

Tags: 67p-churyumov-gerasimenko-1-1969-r1, international-rosetta-mission
Organization: National Aeronautics and Space Administration