AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E401395-T1: [Translated] METHOD FOR TREATING NEURODEGENERATIVE, PSYCHIATRIC AND OTHER DISORDERS USING DEACETYLASE INHIBITORS

The invention relates to a novel method for treating a variety of diseases and disorders, including polyglutamine expansion diseases such as Huntington's disease, neurological degeneration, psychiatric disorders, and protein aggregation disorders and diseases, comprising administering to patients in need thereof of a therapeutically effective amount of one or more deacetylase inhibitors. The invention is also directed to a transgenic fly useful as a model of polyglutamine expansion diseases, which may be used to test potential therapeutic agents.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E399550-T1: [Translated] REMEDIES AND PREVENTIVE AGENTS FOR DIGESTIVE DISEASES CONTAINING DIAMINOTRIFLUOROMETHYLPYRIDINE COMPOUNDS

A digestive system disease therapeutic or preventive agent containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: <CHEM> wherein X is a -CW<1>R<1> group, a -COCOR<2> group, a -CW<1>NHCOR<2> group, a -C(=W<1>)W<2>R<3> group or a -CW<1>N(R<4>)R<5> group; Y is an alkyl group, a -CW<3>R<6> group, a -COCOR<7> group, a -NHCOR<7> group, a -C(=W<3>)W<4>R<8> group, a -(NH)mSO2R<9> group, a -(NH)mSO2OR<10> group or a -(NH)mSO2N(R<11>)R<12> group; each of R<1>, R<6> and R<9> is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R<2> and R<7> is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R<3>, R<8> and R<10> is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R<4>, R<5>, R<11> and R<12> is an alkyl group; each of W<1>, W<2>, W<3> and W<4> is an oxygen atom or a sulfur atom; and m is 0 or 1.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 526359: 3-Bromo-1,2,6,9-tetrachloro-dibenzo-p-dioxin

Chemical compound data from PubChem database. IUPAC Name: 3-bromo-1,2,6,9-tetrachlorodibenzo-p-dioxin. Molecular Formula: C12H3BrCl4O2. Molecular Weight: 400.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E399880-T1: [Translated] AN IN VITRO PROCESS FOR CREATING A DNA LIBRARY

A method for in vitro construction of a library of recombined homologous polynucleotides from a number of different starting DNA templates and primers by induced template shifts during a polynucleotide synthesis is described, whereby: A. extended primers are synthesized by a) denaturing the DNA templates, b) annealing primers to the templates, c) extending the said primers by use of a polymerase, d) stop the synthesis, and e) separate the extended primers from the templates; B. a template shift is induced by a) isolating the extended primers from the templates and repeating steps A.b) to A.e) using the extended primers as both primers and templates, or b) repeating steps A.b) to A.e), C. this process is terminated after an appropriate number of cycles of process steps A. and B.a), A. and B.b), or combinations thereof. Optionally the polynucleotides are amplified in a a standard PCR reaction with specific primers to selectively amplify homologous polynucleotides of interest.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E399835-T1: [Translated] NATURAL GAS HYDRATE AND METHOD FOR THE PRODUCTION THEREOF

A method for the production of the natural gas hydrate characterized by the steps of: combining natural gas and water to form a natural-gas water system and an agent adapted to reduce the natural gas-water interfacial tension to form a natural-gas water-agent system, allowing the natural gas-water-agent system to reach equilibrium at elevated pressure and ambient temperature and reducing the temperature of the natural gas-water-agent system to initiate the formation of the natural gas hydrate.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E400891-T1: [Translated] METHOD FOR FORMING A SILICON EPITAXIAL LAYER

A silicon epitaxial layer is formed on the semiconductor underlayer of a target substrate (W) in the process chamber (2). This forming method includes a pressure reducing step of reducing the pressure inside the process chamber (2) accommodating the target substrate (W), a vapor phase growth step of introducing a film formation gas containing silane gas into the process chamber (2) to grow a silicon epitaxial layer on the semiconductor underlayer, and a hydrogen chloride treatment step and a hydrogen heat treatment step performed therebetween. The hydrogen chloride treatment step is arranged to introduce the first pre-treatment gas containing hydrogen chloride gas into the process chamber (2), thereby treating the atmosphere inside the process chamber (2). The hydrogen heat treatment step is arranged to introduce the second pre-treatment gas containing hydrogen gas into the process chamber (2), thereby treating the surface of the semiconductor underlayer. <IMAGE>

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 530518: 5-Bromovaleric acid, pentadecyl ester

Chemical compound data from PubChem database. IUPAC Name: pentadecyl 5-bromopentanoate. Molecular Formula: C20H39BrO2. Molecular Weight: 391.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526070: 1-Hexadecanol, 14-methyl, TMS

Chemical compound data from PubChem database. IUPAC Name: trimethyl(14-methylhexadecoxy)silane. Molecular Formula: C20H44OSi. Molecular Weight: 328.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528290: Benzene, 1,2,3-trimethyl-5-propyl

Chemical compound data from PubChem database. IUPAC Name: 1,2,3-trimethyl-5-propylbenzene. Molecular Formula: C12H18. Molecular Weight: 162.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E401422-T1: [Translated] METHOD FOR GENERATING A LIBRARY OF BACTERIAL CLONES WITH DIFFERENT GENE EXPRESSION LEVELS

The present invention relates to a method of creating DNA libraries that include an artificial promoter library and/or a modified ribosome binding site library and transforming bacterial host cells with the library to obtain a population of bacterial clones having a range of expression levels for a chromosomal gene of interest.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 530700: 2,3,4-Trifluorobenzoic acid, tridec-2-ynyl ester

Chemical compound data from PubChem database. IUPAC Name: tridec-2-ynyl 2,3,4-trifluorobenzoate. Molecular Formula: C20H25F3O2. Molecular Weight: 354.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
New Legislation — Public Law (P.L.) 117-328, §5131 of Division FF of the Consolidated Appropriations Act, 2023, Enacted December 29, 2022

This Information Memorandum informs title IV-E agencies of how the Consolidated Appropriation Act, 2023 created a transition period for ending the temporary increase in the Federal Medical Assistance Percentage that has been in effect since January 2020 for title IV-E programs.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, federal, grant, policy, social
Organization: U.S. Department of Health & Human Services
Notice of Allotment Percentages to States for Child Welfare Services State Grants

This document provides the allotment percentage for fiscal years 2006 and 2007 for each state under the title IV–B Subpart 1, which is the Child Welfare Services State Grants program.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, fiscal, grant, policy, scope
Organization: U.S. Department of Health & Human Services
Compound 528880: Dopamine, N-acetyl-TFA

Chemical compound data from PubChem database. IUPAC Name: [4-(2-acetamidoethyl)-2-(2,2,2-trifluoroacetyl)oxyphenyl] 2,2,2-trifluoroacetate. Molecular Formula: C14H11F6NO5. Molecular Weight: 387.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400996-T1: [Translated] MILK CUP LINING AND MILK CUP

This invention refers to a teatcup liner and a teatcup. The liner (1) is mounted in a shell (2) of the teatcup and defines an inner space (3) for receiving a teat. The liner includes a primary component (12) forming a barrel. The primary component includes a peripheral portion (15), a primary connecting ring (16) and a lip (17) defining an opening (4). The secondary component includes a secondary peripheral portion (18) and a secondary connecting ring (20). The primary component is connectable to the secondary component for releasing the liner by a mutual engagement of the connecting rings. At least one of the connecting rings abuts the peripheral portion of the other component to form a sealing abutment between the two components.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 528309: Pyrazine, 2-(methylthio)-3-propyl-

Chemical compound data from PubChem database. IUPAC Name: 2-methylsulfanyl-3-propylpyrazine. Molecular Formula: C8H12N2S. Molecular Weight: 168.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 529737: Dimethyl 2-chloro-4-bromo-3-oxopentanedioate

Chemical compound data from PubChem database. IUPAC Name: methyl 4-bromo-2-chloro-3-oxopent-4-enoate. Molecular Formula: C6H6BrClO3. Molecular Weight: 241.47. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528762: 1-(Methylthio)-3-octanone

Chemical compound data from PubChem database. IUPAC Name: 1-methylsulfanyloctan-3-one. Molecular Formula: C9H18OS. Molecular Weight: 174.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Supporting Evidence-Based Home Visitation Programs to Prevent Child Abuse and Neglect Project: The County of Solano Department of Health and Social Services

Location:

Fairfield, California

Home Visiting Program Selected:

Nurse Family Partnership

Home Visiting Target Population:

Low-income, first-time mothers in the County with significant risk factors for child maltreatment, along with pregnant transitional-age youth previously or currently involved in foster care or in relationships with former or current foster care youth.

Project Overview:
The County of Solano Department of Health and Social Services will work closely with community partners currently providing home visitation services, including BabyFirst Solano, a public-private partnership established in 2003 to make sure babies born in the County are healthy and able to thrive, to implement a Nurse Family Partnership (NFP) home visiting program. The Department expects to receive referrals to NFP from a diverse group of collaborative partner agencies and programs such as public health clinics, WIC clinics, family resource centers, and private physicians. To implement the grant, the Department's child welfare and public health divisions will collaborate with each other, including combining funding streams to support NFP. They will also work with mental health, substance abuse treatment, and employment and eligibility divisions. The grantee plans to compare outcomes, costs, and benefits of NFP with other, non-evidence-based home visiting models in the county, and will engage an external evaluator to conduct the evaluation.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, foster, maltreatment, neglect, policy
Organization: U.S. Department of Health & Human Services
Compound 527908: 10-Chlorohexadecyl acetate

Chemical compound data from PubChem database. IUPAC Name: 10-chlorohexadecyl acetate. Molecular Formula: C18H35ClO2. Molecular Weight: 318.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526709: 4-Butyramidophenyl acetate

Chemical compound data from PubChem database. IUPAC Name: [4-(butanoylamino)phenyl] acetate. Molecular Formula: C12H15NO3. Molecular Weight: 221.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526943: 2-Thienyl 1-methyl-2-oxobutyl disulphide

Chemical compound data from PubChem database. IUPAC Name: 2-(thiophen-2-yldisulfanyl)pentan-3-one. Molecular Formula: C9H12OS3. Molecular Weight: 232.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527686: Butanoic acid, 3-chloro, 1-methyl-3-butenyl ester

Chemical compound data from PubChem database. IUPAC Name: pent-4-en-2-yl 3-chlorobutanoate. Molecular Formula: C9H15ClO2. Molecular Weight: 190.67. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400308-T1: [Translated] IMPROVED OSTEOINDUCTIVE MATERIALS

The present invention relates to an osteoinductive material comprising a matrix material with morphogenetic protein(s) absorbed on inner or outer surfaces of this matrix material, wherein the osteoinductive material is obtainable by contacting the matrix material and the morphogenetic protein(s) under conditions of pH and ionic concentration to keep the protein stable and dissolved in a solution until dried and thereby allowing that the matrix material becomes evenly coated with the morphogenetic protein(s). <IMAGE>

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E401588-T1: [Translated] CAMERA

The object of the present invention is to eliminate hitherto restrictive conditions related to photography, like when attempting to register pictures with infinite depth of field, more or less, or attempt full detail-reproduction of light and shade. This is, according to the present invention, accomplished by making several recordings with differing states of focus or exposure, the images registered being similarly subdivided into smaller image-parts and a resultant image bing produced by selecting those image-parts from each set, being most suitable. Optimal image definition of an image-part can for instance be assessed by contrast-measurement techniques or separate range-finding with a laser. An analogous optimal representation of image detail can also be achieved.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 525812: N,N'-bis-(4-Methoxyphenyl)formamidine

Chemical compound data from PubChem database. IUPAC Name: N,N'-bis(4-methoxyphenyl)methanimidamide. Molecular Formula: C15H16N2O2. Molecular Weight: 256.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Child and Family Services Reviews Update Volume 17, Issue 3, June 2023

This issue of Child and Family Services Reviews Update contains the following sections:CFSR Round 4 Is Underway!, APSR Process Integrated With CFSP, New OSRI Course Released on E-Learning Academy, New CFSR Overview Video Released, Spanish Translations Added to Portal, and New Round 4 FAQs Posted.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, child, data, policy, social
Organization: U.S. Department of Health & Human Services
Compound 527762: 2,2-Dichloroethyl nonadecanoate

Chemical compound data from PubChem database. IUPAC Name: 2,2-dichloroethyl nonadecanoate. Molecular Formula: C21H40Cl2O2. Molecular Weight: 395.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526696: 3,4-di-O-acetyl-1,5-anhydro-2-O-methyl-D-fucitol

Chemical compound data from PubChem database. IUPAC Name: (4-acetyloxy-5-methoxy-2-methyloxan-3-yl) acetate. Molecular Formula: C11H18O6. Molecular Weight: 246.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 529521: L-Tryptophan, N,1-bis(tert-butyldimethylsilyl)-, tert-butyldimethylsilyl ester

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]-3-[1-[tert-butyl(dimethyl)silyl]indol-3-yl]propanoate. Molecular Formula: C29H54N2O2Si3. Molecular Weight: 547.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E399637-T1: [Translated] LAMINATE, METHOD FOR THE PRODUCTION THEREOF AND USE OF A LAMINATE, IN PARTICULAR AS A MEDICAL SUPPORT MATERIAL

The invention relates to a laminate, consisting of at least one first layer made of an elastic polymer film and a second layer made of an elastic, flat textile structure. The finished laminate has a micro- and/or macro-embossment.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 528908: 5-Ethenyl-5-(1-methyl-3-butenyl)-hexahydropyrimidine-2,4,6-trione

Chemical compound data from PubChem database. IUPAC Name: 5-ethenyl-5-pent-4-en-2-yl-1,3-diazinane-2,4,6-trione. Molecular Formula: C11H14N2O3. Molecular Weight: 222.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 530112: Nonane, 5-ethyl

Chemical compound data from PubChem database. IUPAC Name: 5-ethylnonane. Molecular Formula: C11H24. Molecular Weight: 156.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 530595: 4-Cyanobenzoic acid, 2-adamantyl ester

Chemical compound data from PubChem database. IUPAC Name: 2-adamantyl 4-cyanobenzoate. Molecular Formula: C18H19NO2. Molecular Weight: 281.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 529485: Ethyl 1-(1,1-dioxido-1,2-benzisothiazol-3-yl)-4-piperidinecarboxylate

Chemical compound data from PubChem database. IUPAC Name: 3-hydroxy-6-methyl-2,3-dihydropyran-4-one. Molecular Formula: C6H8O3. Molecular Weight: 128.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527131: (Hexan-2-yl)(methyl)amine

Chemical compound data from PubChem database. IUPAC Name: N-methylhexan-2-amine. Molecular Formula: C7H17N. Molecular Weight: 115.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
AFCARS Report #21

This report provides preliminary estimates of AFCARS data for FY 2013. Preliminary reports of AFCARS data include data received by September 30 for the report period ending March 31 and by March 31 for the report period ending September 30. This generally encompasses the required data submissions and submission of corrected data by States to avoid possible financial penalties.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, child, data, policy, reporting
Organization: U.S. Department of Health & Human Services