AndreaBozzo/ceres-open-data-index huggingface dataset:
Digest of United States Practice in International Law 2001

The Office of the Legal Adviser publishes the annual Digest of United States Practice in International Law to provide the public with a historical record of the views and practice of the Government of the United States in public and private international law. "In his introduction to the 2001 volume, then Legal Adviser William H. Taft IV stated in part: "2001 will likely prove to have been a watershed in the development of international law. In this field, as in so many other ways, the tragic, traumatic events of September 11 altered the landscape of U.S. practice. Issues of use of force, self-defense, and counter-terrorism, which have always been important, have posed unforeseen challenges in unanticipated contexts. Policy makers have been confronted by new questions related to humanitarian law, the law of war, and international criminal law. The various domestic and international responses to terrorism, including economic and trade sanctions, the freezing and seizing of assets, claims for compensation, and civil litigation, have each generated new and unique problems, to which the legal responses continue to develop. "At the same time, 2001 witnessed many other significant developments not directly related to the events of September 11, both through United States participation in international fora and developments in the application of international law in the United States. These cover the full range of topics in international legal practice, from treaties to consular affairs, the environment, and private international law. . . ."

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Organization: Department of State
Digest of United States Practice in International Law 2000

The Office of the Legal Adviser publishes the annual Digest of United States Practice in International Law to provide the public with a historical record of the views and practice of the Government of the United States in public and private international law. The 2000 volume covers significant legal developments that occurred during 2000. The edition provides documentary excerpts and other information concerning developments in the areas of nationality, citizenship, and immigration (chapter 1); consular and judicial assistance and related issues (chapter 2), international criminal law (chapter 3); treaties and other international agreements (chapter 4); federal foreign affairs authority (chapter 5); human rights and humanitarian law (chapter 6); international organizations and multilateral institutions (chapter 7); international claims and state responsibility (chapter 8); diplomatic relations, continuity and succession of states (chapter 9); immunities and related issues (chapter 10); trade, commercial relations, investment and transportation (chapter 11); territorial regimes and related issues (chapter 12); environment and other transnational scientific issues (chapter 13); private international law (chapter 14); sanctions (chapter 15); and use of force and arms control (chapter 16). In his introduction to the 2000 Digest, then Legal Adviser William H. Taft IV provided an overview of the methodology used in preparing the volume and the history of the Digest.

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Organization: Department of State
Digest of United States Practice in International Law 1991-1999

The Office of the Legal Adviser publishes the annual Digest of United States Practice in International Law to provide the public with a historical record of the views and practice of the Government of the United States in public and private international law. In his introduction to the Digest covering 1991-1999, then Legal Adviser John B. Bellinger, III, summarized its contents, stating in part: "During this period, for instance, the United States became party to important human rights treaties, including the International Covenant on Civil and Political Rights, the UN Convention Against Torture and Other Cruel, Inhuman, or Degrading Treatment or Punishment, and the International Convention on the Elimination of All Forms of Racial Discrimination. International terrorist acts such as the bombing of Pan Am 103 over Lockerbie, Scotland, posed new challenges, to which the United States responded through negotiation of new international terrorism conventions, efforts in both the UN Security Council and the International Court of Justice, and changes in U.S. domestic laws . . . . "Legal issues involving the use of force arose with U.S. participation in the Gulf War and the military intervention in the territory of the Former Yugoslavia, and were addressed in several instances before the International Court of Justice. U.S. participation in the peace process and in peacekeeping in areas as diverse as the Middle East, Bosnia, Kosovo, Somalia, and Haiti gave rise to both international and domestic legal issues. Major efforts were pursued in arms control and nuclear non-proliferation, including the establishment of the Korean Energy Development Organization. "The 1990s were an era of new international institutions and political structures. The United States was actively engaged, for instance, in the Security Council's creation of the international criminal tribunals for the former Yugoslavia and for Rwanda and the UN Mission in Kosovo.

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Organization: Department of State
Digest of United States Practice in International Law 1989-1990

The Office of the Legal Adviser publishes the annual Digest of United States Practice in International Law to provide the public with a historical record of the views and practice of the Government of the United States in public and private international law. In his April 2003 introduction to the 1989-1990 Digest, then Legal Adviser William H. Taft IV stated in part: "The year 1989-90 was a transitional period in international relations, as the world community continued to deal with implications of the end of the Cold War and the unsteady emergence of a new era. Many of the tensions and ambiguities of the time are reflected in the documents excerpted in this volume. For example, the Immigration Act of 1990 was adopted against the background of domestic U.S. concerns about terrorism, admission of refugees and exclusion of aliens-issues that continue to be important today. Other significant domestic law issues involved reservations to treaties (in this case, the 1948 Genocide Convention), the application of doctrines of foreign sovereign immunity (the Wallenberg Case), the interplay between sanctions and foreign assistance (e.g., Hungary, Poland, Czechoslovakia and the German Democratic Republic), and the allocation of foreign affairs authority in our federal system. "At the same time, the volume records U.S. efforts to deal effectively with the legal dimensions of very diverse issues on the international plane, including the Iraqi attack on the U.S.S. Stark, the downing of Iran Air Flight 655, the deployment of U.S. armed forces in Panama, maritime interdiction incidents, irregular rendition of criminal suspects, and the Treaty on Conventional Forces in Europe. Concerns about human rights, terrorism, and the war on drugs are indicated by the adoption of domestic legislation implementing, or relating to the implementation of, the UN Convention on Torture and Other Cruel, Inhuman or Degrading Treatment or Punishment.

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Organization: Department of State
Digest of United States Practice in International Law 2002

The Office of the Legal Adviser publishes the annual Digest of United States Practice in International Law to provide the public with a historical record of the views and practice of the Government of the United States in public and private international law. "In his introduction to the 2002 volume, then Legal Adviser William H. Taft IV stated in part: "Calendar year 2002 gave rise to a broad range of significant and sometimes novel issues of international law. Many developments again highlighted the need to protect our national security against a different kind of enemy through the use of force in self-defense, non-proliferation and arms control efforts, the detention of unlawful enemy combatants and establishment of military commissions, continued counter-terrorism efforts, the imposition of sanctions, and the freezing of governmental assets, sometimes made available for payment of claims by individuals against terrorist states. At the same time, there were notable developments in non-confrontational contexts, including the fields of human rights, trade and investment, law of the sea, international claims and state responsibility, treaty practice, and international crime. . . ."

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Organization: Department of State
Africa: Conflicts Without Borders 2009

Conflicts Without Borders , which visualizes conflict in Africa as sub-national and transnational areas of armed conflict, inter-communal strife, and political violence that occurred in the first seven months of 2009. Areas of conflict were drawn around locations of reported conflict incidents in 2009, as well as around concentrations of internally displaced persons inside affected countries and cross-border rebel bases and refugee camps in neighboring countries.

Tags: africaconflict
Organization: Department of State
SIMS FY19Q2-FY20Q1 Global

The Site Improvemnet Through Monitoring Systems (SIMS) is a quality assurance methodology used to increase the impact of PEPFAR programs on the HIV epidemic through standardized monitoring of the quality of services at the site- and above-site levels. A data dictionary that accompanies the dataset can be found <a href=https://s3.amazonaws.com/media.data.pepfar.gov/sims_downloadables/SIMS.Data.Dictionary.to.accompany.downloadable.datasets.pdf target=blank>here</a>. Detailed materials about SIMS can be found <a href=https://datim.zendesk.com/hc/en-us/sections/200929305-SIMS target=blank>here</a>.

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Organization: Department of State
PEPFAR PEPFAR IATI Activity

PEPFAR participates in the International Aid Transparency Initiative (IATI) by submitting data periodically to the IATI registry. The data provided in the PEPFAR IATI Activity file includes two core types of data:1. Monitoring, Evaluation, and Reporting (MER) data, consisting of MER Targets and Results.2. Financial data, consisting of Budget and Expenditures For information the contents and use of the PEPFAR IATI file, please visit the <a href=https://s3.amazonaws.com/media.data.pepfar.gov/additionalData/iati_activity/PEPFAR.IATI.Activity.File.Users.Guide.pdf target=blank>PEPFAR IATI Activity File Users Guide</a>.

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Organization: Department of State
PEPFAR Voluntary Male Medical Circumcisions

This data set contains Yearly results by Operating Unit for Fisal Years 2007-2019. Data can be downloaded as a compressed (zip) file, which contains text files in csv (comma separated values) format. For indicator definitions, please consult the latest <a href=https://www.state.gov/wp-content/uploads/2019/10/PEPFAR-MER-Indicator-Reference-Guide-Version-2.4-FY20.pdf target=blank>MER Indicator Reference Guide</a>.For additional PEPFAR data, please visit data.pepfar.gov. Unless otherwise noted, the content, data, documentation, code, and related materials on data.pepfar.gov is public domain and made available with a Creative Commons CC0 1.0 Universal dedication and license-free (per US Code 17 USC § 105). Citation of data.pepfar.gov as a source of the data is appreciated.

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Organization: Department of State
PEPFAR Results by Age and Sex

This data set contains Quarterly Results and yearly Targets by Operating Unit, Sub-National Units 1–2, PSNU Prioritization, Coarse Age and Sex for Fiscal Years 2016 – 2020 and the  following subset of Testing and Treatment indicators: HTS_TST (People receiving testing and counseling services), HTS_TST_POS (People newly testing positive for HIV), TX_CURR (People currently receiving ART), TX_NEW (People newly enrolled in ART), TX_PVLS (Viral Load Documented) and TX_RET (People who have remained in treatment 12 months after ART initiation). Data can be downloaded as a compressed (zip) file, which contains text files in csv (comma separated values) format. For indicator definitions, please consult the latest <a href=https://www.state.gov/wp-content/uploads/2019/10/PEPFAR-MER-Indicator-Reference-Guide-Version-2.4-FY20.pdf target=blank>MER Indicator Reference Guide</a>.For additional PEPFAR data, please visit data.pepfar.gov. Unless otherwise noted, the content, data, documentation, code, and related materials on data.pepfar.gov is public domain and made available with a Creative Commons CC0 1.0 Universal dedication and license-free (per US Code 17 USC § 105). Citation of data.pepfar.gov as a source of the data is appreciated.

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Organization: Department of State
Maumee River 2012 and 2016

The Maumee River and associated tributaries are an example of a system influenced by a mosaic of contaminant inputs from point and nonpoint sources along a gradient of land uses. To assess the potential effects of contaminants on aquatic biota in a system this complex requires a combination of targeted and nontargeted analytical and biological monitoring techniques to provide data that can be assembled and interpreted in an integrated manner. The aim of the current paper was to provide a practical demonstration of this type of approach using a variety of state-of-the-science pathway-based tools. Studies conducted in 2012 and 2106 showed that contaminants in the upper part of the Maumee River reflect agricultural practices, while downstream, the suite of chemicals present includes those from agriculture in conjunction with contaminants more indicative of a general urban setting, influenced in some areas by WWTP inputs. Biological responses using in vitro assays with surface water samples, and measures of biological responses in caged fish deployed a various sites in the Maumee River were used to assess the potential for perturbation of specific biological pathways. Overall there was little evidence for contaminant effects on endocrine pathways involved is reproduction or development. However, multiple lines of evidence suggested the presence of contaminants that could inhibit or induce  cytochrome P450-based enzymes thereby influencing biological pathways/processes associated with these ubiquitous proteins. 

This dataset is associated with the following publication:
Ankley, G., J. Berninger, B. Blackwell, J. Cavallin, T. Collette, D. Ekman, K. Fay, D. Feifarek, K. Jensen, M. Kahl, J. Mosley, S. Poole, E. Randolph, D. Rearick, A. Schroeder, J. Swintek, and D. Villeneuve. Pathway-based approaches for assessing biological hazards of complex mixtures of contaminants: A case study in the Maumee River.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 40(4): 1098–1122, (2021).

Tags: adverse-outcome-pathway, aquatic-ecosystems, contaminant-mixtures, ecotoxicology, endocrine-disruption, field, screening-and-prioritization
Organization: U.S. Environmental Protection Agency
Dataset for ORD-033344: A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays

Microarray experiments used in the study. 

This dataset is associated with the following publication:
Corton, J., T. Hill, J. Sutherland, J. Stevens, and J. Rooney. A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  177(1): 11-26, (2020).

Tags: 2-year-bioassay, adverse-outcome-pathway, liver-cancer, molecular-initiating-event, toxicogenomics
Organization: U.S. Environmental Protection Agency
Evaluation of polycyclic aromatic hydrocarbons in fine particulate matter censoring-related bias.csv

The case study data are selected from an EPA study using cookstove combustion experiments to measure polycyclic aromatic hydrocarbon (PAH) concentrations in particulate matter (PM) and were determined using gas chromatography-mass spectrometry (GC-MS) (Shen et al. 2017). Chromatograms of particle emissions reported in Shen et al. (2017) were reanalyzed for the case study to quantify previously censored measurements where the signal-to-noise ratio was >1. 

This dataset is associated with the following publication:
George, B., L. Gains-Germain, K. Broms, K. Black, M. Furman, M. Hays, K. Thomas, and J.E. Simmons. Censoring Trace-Level Environmental Data: Statistical Analysis Considerations to Limit Bias.   ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 55(6): 3786-3795, (2021).

Tags: bias, censoring, nondetects
Organization: U.S. Environmental Protection Agency
Metadata Files for Structure-based QSAR models to predict repeat dose toxicity points of departure

This paper describes a model to take chemical structures and predict a property (the point of departure) for a new chemical. No new data were generated. The contents of this zip file contains metadata that you could use to make a model prediction. It does contain all of the code and a help file describing how to run the model. 

This dataset is associated with the following publication:
Pradeep, P., K. Paul-Friedman, and R. Judson. Structure-based QSAR Models to Predict Repeat Dose Toxicity Points of Departure.   Computational Toxicology. Elsevier B.V., Amsterdam,  NETHERLANDS, 16(November 2020): 100139, (2020).

Tags: point-of-departure, qsar, repeat-dose-toxicity, systemic-toxicity
Organization: U.S. Environmental Protection Agency
Effects-based monitoring of bioactive contaminants discharged to the Colorado River before and after a municipal wastewater treatment facility replacement

The present study highlights the utility of bioeffects-based monitoring in conjunction with analytical chemical measurements of surface waters on the Colorado River associated with a historically bioactive wastewater treatment plant effluent. Concurrent with chemical monitoring and in vitro bioactivity measurements, in situ caged fish systems were employed to evaluate the potential bioavailability of predicted biologically-active contaminants associated with ER, GR, and PPAR-associated activities. The present study compares the effects of a wastewater treatment plant facility upgrade on bioactive contaminant loading. 

This dataset is associated with the following publication:
Cavallin, J., W. Battaglin, J. Beihoffer, B. Blackwell, P. Bradley, A. Cole, D. Ekman, R. Hofer, J. Kinsey, K. Keteles, D. Winkelman, and D. Villeneuve. Effects-Based Monitoring of Bioactive Chemicals Discharged to the Colorado River Before and After a Municipal Wastewater Treatment Plant Replacement.   ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 55(2): 974-984, (2021).

Tags: adverse-outcome-pathway, aquatic-ecosystems, ecotoxicology, endocrine-disruption, fish, in-vitro-bioassays, screening-and-prioritization, wastewater-treatment-plant
Organization: U.S. Environmental Protection Agency
Machine Learning Modeling of Water Quality Based Risk Assessment

This is the geospatial and hydroclimate input data used to develop data-driven Machine Learning (ML) models as well as model estimated water quality based risk metrics and watershed health composite measure in three river basins in the Midwest. Model outputs that are used to construct the figures in the paper are displayed in the Excel file with the definitions of the data reported in each datasheet. The directory to the GIS data that were used to construct the inputs and spatially distributed risk metrics at the HUC-10 level is listed here and in the Scientific Data Management Plan. Portions of this dataset are inaccessible because: Large size GIS database. They can be accessed through the following means: C:\Users\MHantush\OneDrive - Environmental Protection Agency (EPA)\ScienceHUB\WH ML Modeling. Format: Generic GIS database. 

Tags: machine-learning, risk-analysis, ungauged-watersheds, water-quality
Organization: U.S. Environmental Protection Agency
Human Iodotyrosine Deiodinase Inhibition Assay: Screening of ToxCast Phase 1_v2, Phase 2, and e1k Chemical Libraries

The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the ToxCast Phase 1_v2, Phase 2, and e1k chemical libraries, as well as a few additional target chemicals from ToxCast Phase 3 library or used in assay development. Over 1,800 chemicals were tested in total. This data set includes the list of chemicals tested and the median, minimum, and maximum inhibition produced by each chemical when screened at target high concentration of 200 µM. 154 chemicals were further tested in concentration response, and the median, minimum, and maximum inhibition produced at each concentration for those chemicals are included. A model inhibitor (3-Nitro-L-Tyrosine) was included on each plate as a positive control, with concentration response data for those curves also included in the data set. 

This dataset is associated with the following publication:
Olker, J., J. Korte, J. Denny, J. Haselman, P. Hartig, M. Cardon, M. Hornung, and S. Degitz. In Vitro Screening for Chemical Inhibition of the Iodide Recycling Enzyme, Iodotyrosine Deiodinase.   TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY,  71: 105073, (2021).

Tags: chemical-screening, endocrine, in-vitro-assay, iodotyrosine-deiodinase, thyroid-hormone
Organization: U.S. Environmental Protection Agency
Vitamin D deficiency causes cardiac dysfunction mediated by TRPC6_complete data

Cardiovascular effects of vitamin D deficiency and pharmacological characterization of the role of TRPC6 in the effects. 

This dataset is associated with the following publication:
Stratford, K., N. Coates, L. Thompson, A. Farraj, and M. Hazari. Early-life persistent vitamin D deficiency-induced cardiovascular dysfunction in mice is mediated by Transit Receptor Potential C Channels.   The Journal of Steroid Biochemistry and Molecular Bio. ELSEVIER, AMSTERDAM,  HOLLAND, 206(105804): 1, (2021).

Tags: cardiovascular, hypertension, trpc6, vitamin-d-deficiency
Organization: U.S. Environmental Protection Agency
Risk-based Decision Support Tool (DST) for TMDL analysis and Watershed Health assessment demonstration dataset (Upper Mississippi River Basin, Ohio River Basin, Maumee River Basin)

The data set is composed of inputs and outputs of the DST demonstration and application to risk-based TMDLs and water quality risk assessment in Midwest river basins (Upper Mississippi River, Ohio River, and Maumee River). Portions of this dataset are inaccessible because: Too large. They can be accessed through the following means: The data is available in this directory: C:\Users\MHantush\OneDrive - Environmental Protection Agency (EPA)\ScienceHUB\Risk-Based WH-TMDL Tool\gis_files. Format: GIS data files. 

This dataset is associated with the following publication:
Mallya, G., A. Gupta, M.M. Hantush, and R.S. Govindaraju. Uncertainty quantification in reconstruction of sparse water quality time series: Implications for watershed health and risk-based TMDL assessment.   ENVIRONMENTAL MODELLING AND SOFTWARE. Elsevier Science Ltd, New York, NY, USA, 131: 104735, (2020).

Tags: decision-support-tool, loadest, relevance-vector-machine, tmdl, tmdls, uncertainty-analysis, uncertainty-quantification, water-quality-risk-analysis
Organization: U.S. Environmental Protection Agency