AndreaBozzo/ceres-open-data-index huggingface dataset:
2018 Uniform Reporting System (URS) Table for Arizona

This is the 2018 Uniform Reporting System (URS) Output Tables for Arizona. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: arizona-mental-health, mental-health-services, noms-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Research Article: BMC Medical Genetics

Background
          Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC also known as CD45) in a large cohort of German MS patients and controls. Different isoforms of the protein are expressed, depending on alternative splicing of exons 4 (CD45RA), 5 (CD45RB) and 6 (CD45RC) (CD45RO, exons 4–6 spliced out). The 77C→G transition does not change the amino acid sequence, but it is probably part of a motif necessary for splicing leading to the isoform CD45RA. The expression of CD45RA is increased in 77C/G heterozygous individuals. The aim of the study was to clarify the importance of the PTPRC 77C→G transition in our German cohort of MS patients.
        
        
          Methods
          PCR products of exon 4 were digested using endonuclease MspI. The resulting restriction fragments of the wildtype C allele are 198 and 62 bp in length. In the G allele an additional restriction site is present yielding fragments of 114 and 84 bp.
        
        
          Results
          The G allele was identified in 10 of the 347 controls (1.4%) and in 7 of 454 MS patients (0.8%; Table 1). No homozygous individuals were found either in the control or in the patient group. Genetic association between the PTPRC 77C→G transition and MS susceptibility was excluded in the MS cohort. In addition, subgrouping patients according to differences in the clinical course of MS or according to HLA-DRB1*15 status did not yield significant differences.
        
        
          Conclusions
          The 77C→G transition in exon 4 of the PTPRC gene may contribute to MS susceptibility only in very few families, if at all, but it is not relevant for the majority of MS cases, including virtually all German patients.

Tags: cd45, genetic-association-study, multiple-sclerosis, nih, ptprc-gene
Organization: U.S. Department of Health & Human Services
2022 Uniform Reporting System (URS) Table For Iowa

This is the 2022 Uniform Reporting System (URS) Output Tables for Iowa. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, iowa, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Determinants of blood pH in health and disease

An advanced understanding of acid–base physiology is as central to			 the practice of critical care medicine, as are an understanding of cardiac and			 pulmonary physiology. Intensivists spend much of their time managing problems			 related to fluids, electrolytes, and blood pH. Recent advances in the			 understanding of acid–base physiology have occurred as the result of the			 application of basic physical-chemical principles of aqueous solutions to blood			 plasma. This analysis has revealed three independent variables that regulate pH			 in blood plasma. These variables are carbon dioxide, relative electrolyte			 concentrations, and total weak acid concentrations. All changes in blood pH, in			 health and in disease, occur through changes in these three variables. Clinical			 implications for these findings are also discussed.

Tags: acid-base-balance, acidosis-alkalosis, blood-ph, electrolyte-concentrations, nih
Organization: U.S. Department of Health & Human Services
Compound 527391: 26-Methyl-octacosyl cyanide

Chemical compound data from PubChem database. IUPAC Name: 27-methylnonacosanenitrile. Molecular Formula: C30H59N. Molecular Weight: 433.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2010-2012 NSDUH Substate Region Definitions

This report discusses the substate region definitions and maps used in the 2010 to 2012 National Survey on Drug Use and Health (NSDUH) report that assesses past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older by 362 substate regions within the 50 States and the District of Columbia.

Tags: alcohol-disorder, drug-use-disorder, samhsa, substance-use, substate-regions
Organization: U.S. Department of Health & Human Services
Opinion: The clinical use of selective digestive decontamination

Several recent meta-analyses have shown that the use of SDD can reduce the occurrence of nosocomial pneumonia among ventilated patients in the intensive care unit (ICU) setting. However, the use of SDD has also been demonstrated to increase subsequent patient colonization and infection with antibiotic-resistant bacteria, particularly Gram-positive cocci. Therefore, the routine use of SDD cannot be advocated at the present time. The mortality benefit of SDD appears to occur in surgical/trauma patients, and to be associated primarily with the administration of parenteral antibiotics. This is already an accepted practice in most patients during the perioperative period (eg prophylactic parenteral antibiotics for 24 h). Prolonged decontamination of the aerodigestive tract with topical antimicrobials does not appear to influence outcome, and should not be routinely employed.

Tags: antibiotic-resistance, icu-patients, nih, nosocomial-pneumonia, selective-digestive-decontamination
Organization: U.S. Department of Health & Human Services
Receiving Adoption Subsidy: 10/1/2011 - 9/30/2012

This report provides state-specific data from fiscal year 2012 about the number of children who are adopted through a public agency and who receive an adoption subsidy.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, child, data, fiscal, policy
Organization: U.S. Department of Health & Human Services
2018 Uniform Reporting System (URS) Table for Kansas

This is the 2018 Uniform Reporting System (URS) Output Tables for Kansas. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.Report Level

Tags: kansas-mental-health, mental-health-services, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Compound 525588: N,N-Dimethyl-N'-(4-bromophenyl)-p-methoxybenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-bromophenyl)-4-methoxy-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H17BrN2O. Molecular Weight: 333.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
TANF Contingency Fund Awards

Contingency Funds are additional Federal funds available to States, at their request, when unfavorable economic conditions exist. They are considered provisional payments, according to section 403(b)(3)(A) of the Act. This is because the exact amount of Contingency Funds that the State may actually keep is not determined until after the fiscal year ends, not when payment is made. A State that receives a provisional payment must meet specific spending requirements to keep some or all of the Contingency Funds. Data files are by state and year.

<b>Units of Response: </b>State TANF Programs

<b>Type of Data: </b>Financial

<b>Tribal Data: </b>No

<b>COVID-19 Data: </b>No

<b>Periodicity: </b>Annual

<b>SORN: </b>https://www.federalregister.gov/documents/2018/02/14/2018-03014/privacy-act-of-1974-system-of-records

<b>Data Use Agreement: </b>Unavailable

<b>Data Use Agreement Location: </b>Unavailable

<b>Equity Indicators: </b>Unavailable

<b>Granularity: </b>State

<b>Spatial: </b>United States

<b>Geocoding: </b>State

Tags: family-assistance
Organization: U.S. Department of Health & Human Services
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins

Background
          NGF exerts a variety of actions including promotion of neuronal differentiation and survival. The PC12 rat pheochromocytoma cell line has proved valuable for studying how NGF works and has revealed that the NGF mechanism includes regulation of gene expression. Accordingly, we used SAGE (Serial Analysis of Gene Expression) to compare levels of specific transcripts in PC12 cells before and after long-term NGF exposure. Of the approximately 22,000 transcripts detected and quantified, 4% are NGF-regulated by 6-fold or more. Here, we used database information to identify transcripts in our SAGE libraries that encode ribosomal proteins and have compared the effect of NGF on their relative levels of expression.
        
        
          Results
          Among the transcripts detected in our SAGE analysis, 74 were identified as encoding ribosomal proteins. Ribosomal protein transcripts were among the most abundantly expressed and, for naive and NGF-treated PC12 cells, represented 5.2% and 3.5%, respectively, of total transcripts analyzed. Surprisingly, nearly half of ribosomal protein transcripts underwent statistically significant NGF-promoted alterations in relative abundance, with changes of up to 5-fold. Of the changes, approximately 2/3 represented decreases. A time course revealed that the relative abundance of transcripts encoding RPL9 increases within 1 hr of NGF treatment and is maximally elevated by 8 hr.
        
        
          Conclusions
          These data establish that NGF selectively changes expression of ribosomal protein transcripts. These findings raise potential roles for regulation of ribosomal protein transcripts in NGF-promoted withdrawal from the cell cycle and neuronal differentiation and indicate that regulation of individual ribosomal protein transcripts is cell- and stimulus-specific.

Tags: gene-expression, nerve-growth-factor, nih, pc12-cells, ribosomal-proteins
Organization: U.S. Department of Health & Human Services
National Admissions to Substance Abuse Treatment Services - Treatment Episode Data Set (TEDS) Highlights - 2002

This report presents summary results from the Treatment Episode Data Set (TEDS) for 2002. The report provides information on the demographic and substance abuse characteristics of the 1.9 million people admitted to treatment for abuse of alcohol and drugs that year to facilities that report to individual state administrative data systems.

Tags: alcohol-drug-abuse, national-admissions-data, samhsa, substance-abuse-treatment, treatment-episode-data
Organization: U.S. Department of Health & Human Services
2010 CMHS Uniform Reporting System (URS) Output Tables for New York

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, community-mental-health, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services
2012-2014 NSDUH Overview and Summary of Substate Region Estimation Methodology

This report provides a guide to the development and presentation of 2012-2014 NSDUH substate estimates. A summary of the estimation methodology is included as well as sample sizes, response rates, and population estimates.

Tags: mental-health, population-estimates, samhsa, substance-use, survey-methodology
Organization: U.S. Department of Health & Human Services
2019 Uniform Reporting System (URS) Output Tables

These are the 2019 Uniform Reporting System (URS) Output Tables. URS is a state, national, and territories reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, samhsa, state-mental-health
Organization: U.S. Department of Health & Human Services
Risk factors for acquisition of hepatitis C virus infection: a case series and potential implications for disease surveillance

Background
          Transmission of hepatitis C vims (HCV) is strongly associated with use of contaminated blood products and injection drugs. Other "non-parental" modes of transmission including sexual activity have been increasingly recognized. We examined risk factors for acquiring HCV in patients who were referred to two tertiary care centers and enrolled in an antiviral therapy protocol.
        
        
          Methods
          Interviews of 148 patients were conducted apart from their physician evaluation using a structured questionnaire covering demographics and risk factors for HCV acquisition.
        
        
          Results
          Risk factors (blood products, injection/intranasal drugs, razor blades/ toothbrushes, body/ear piercing, occupational exposure, sexual activity) were identified in 141 (95.3%) of participants; 23 (15.5%) had one (most frequently blood or drug exposure), 41 (27.7%) had two, and 84 (53.4%) had more than two risk factors. No patient reported sexual activity as a sole risk factor. Body piercing accounted for a high number of exposures in women. Men were more likely to have exposure to street drugs but less exposure to blood products than women. Blood product exposure was less common in younger than older HCV patients.
        
        
          Conclusion
          One and often multiple risk factors could be identified in nearly all HCV-infected patients seen in a referral practice. None named sexual transmission as the sole risk factor. The development of a more complete profile of factors contributing to transmission of HCV infection may assist in clinical and preventive efforts. The recognition of the potential presence of multiple risk factors may have important implications in the approach to HCV surveillance, and particularly the use of hierarchical algorithms in the study of risk factors.

Tags: case-series, hcv-transmission, hepatitis-c, nih, risk-factors
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: District of Columbia, 2013

This is a behavioral health report for District of Columbia. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, and substance use treatment for the years 2008 to 2012.

Tags: behavioral-health, dc-health, mental-health, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Honolulu, HI

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Honolulu, HI metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for the Honolulu metro area, Hawaii, and the U.S. overall.

Tags: honolulu-metro, major-depression, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Child Abuse Prevention and Enforcement Act, 2000

Title I: The Child Abuse Prevention and Enforcement Act - Child Abuse Prevention and Enforcement Act - Amends the Crime Identification Technology Act of 1998 to authorize the use of funds under the State grant program for criminal justice identification, information, and communication for programs to develop, update, or upgrade the capability of the criminal justice system to deliver timely, accurate, and complete criminal history record information to child welfare agencies, organizations, and programs that are engaged in the assessment of activities related to the protection of children, including protection against child sexual abuse and placement of children in foster care.

(Sec. 103) Amends the Omnibus Crime Control and Safe Streets Act of 1968 to allow the use of drug control and system improvement (Byrne) grants to be used: (1) to enforce child abuse and neglect laws, including laws protecting against child sexual abuse, and to promote programs designed to prevent child abuse and neglect; and (2) to establish or support cooperative programs between law enforcement and media organizations to collect, record, retain, and disseminate information useful in the identification and apprehension of suspected criminal offenders.

(Sec. 104) Amends the Victims of Crime Act of 1984 to provide for a conditional adjustment in the set aside for child abuse victims. Directs that such adjustment be implemented so that any increase in funding provided shall operate notwithstanding any dollar limitation on the availability of the Crime Victims Fund.

Title II: Jennifer's Law - Jennifer's Law - Authorizes the Attorney General to provide grant awards to enable States to improve the reporting of unidentified and missing persons. Authorizes appropriations.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, grant, policy, prevention, real
Organization: U.S. Department of Health & Human Services
Letter to Update Child Welfare Directors on the Title IV-E Prevention Services Clearinghouse

This letter provides an update to states on the progress made in implementing the Title IV-E Prevention Services Clearinghouse, as authorized by the Family First Prevention Services Act, and outlines estimated dates for additional guidance.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, guidance, policy, prevention, scope
Organization: U.S. Department of Health & Human Services
Compound 528541: Hexadecane, 7-undecyl

Chemical compound data from PubChem database. IUPAC Name: 10-hexylhenicosane. Molecular Formula: C27H56. Molecular Weight: 380.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2014 CMHS Uniform Reporting System (URS) Table for Puerto Rico

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Puerto Rico. The URS territories reporting system is collected annually to support the Community Mental Health Services Block Grant program. Territories Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, noms-measures, puerto-rico, samhsa
Organization: U.S. Department of Health & Human Services
2013 CMHS Uniform Reporting System (URS) Tables Alaska

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Alaska for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Debate: The slippery slope of surrogate outcomes

Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial [ALLHAT]) underscore this problem since their results contradicted what was expected based on the surrogate outcomes. The current regulatory policy to allow new therapies to be introduced onto the market based solely on surrogate outcomes may need to be reviewed.

Tags: cardiovascular-outcomes, clinical-trial-validity, nih, surrogate-endpoints, treatment-efficacy
Organization: U.S. Department of Health & Human Services
Debate: Should the elderly receive thrombolytic therapy, or primary angioplasty, for acute myocardial infarction? The case for primary angioplasty

As the population ages the number of elderly patients presenting with acute myocardial infarction (AMI) will continue to increase. There has been no head-to-head trial of thrombolytic therapy versus primary percutaneous coronary intervention (PCI) in this patient cohort, but there is evidence that favors primary PCI. Most elderly patients are candidates for primary PCI, but many have contraindications to thrombolytic therapy. Hemorrhagic complications are more common in the elderly, and many of these patients present with conditions in which thrombolytic agents have decreased efficacy, such as heart failure or prior bypass surgery. PCI can also obviate the need for further risk stratification in most patients.

Tags: acute-myocardial-infarction, elderly-patients, nih, primary-angioplasty, thrombolytic-therapy
Organization: U.S. Department of Health & Human Services