AndreaBozzo/ceres-open-data-index huggingface dataset:
Prevalence of hepatitis B and C markers in high-risk hospitalised patients in Crete: a five-year observational study

Background
          So far the prevalence of viral hepatitis infection in hospitalized patients has not been extensively studied. Therefore we conducted the present five-year observational study to evaluate the prevalence of HBV and HCV infection in high-risk hospitalized patients of Crete, the largest Greek island, Due to the homogeneous population, epidemiological studies can be accurately done.
        
        
          Methods
          The study was carried out in two out of four District General Hospitals, and in the University Hospital of the island. Markers for HBV and HCV were studied and statistically evaluated according to age, sex and geographical area, in a well-defined hospitalized population.
        
        
          Results
          The total prevalence of HBsAg and anti-HCV in the three prefectures during the five-year study is 2.66% and 4.75% respectively. Overall the relative risks were higher in males than females for each hepatitis marker (p < 0.001). Higher prevalence of HBcAb was found in the 41–60 years age group for both sexes (males 36.17%, females 27.38%). Peak HBsAg prevalence was found in the age group of 21–40 and 41–60 years for males (5.4%) and females (3.09%) respectively. Anti-HCV prevalence increases with age reaching the highest prevalence in the age group of 41–60 years for males (7.19%) and in the 61–90 years age group for females (7.16%). For both sexes significant differences between the three locations were identified. For HBsAg a higher prevalence in Heraklion (3.96%) compared to Chania (2.30%, males: p < 0.0001, females: p < 0.05) and Rethymnon (1.45%, males: p < 0.01, females: p < 0.0001) was detected. For HCV a significantly higher prevalence in Heraklion (6.54%) compared to Chania (2.39%, males: p < 0.001, females: p < 0.001) but not in Rethymnon (5.15%, NS). A lower prevalence rate of HBcAb in Heraklion compared to Chania (20.07% versus 23.05%, males: p < 0.001, females: p < 0.001) was found.
        
        
          Conclusions
          These results were possibly overestimated, but nevertheless reflect the situation of the general population within the island as shown by our previous publications in other study groups. Moreover they contribute to the mapping of viral hepatitis prevalence in a geographical area of Southern Europe and may be helpful in planning public health interventional strategies.

Tags: disease-prevalence, hepatitis-b, hepatitis-c, hospitalized-patients, nih
Organization: U.S. Department of Health & Human Services
Publications Using SAMHSA DataNew York City – 5 Boros: Drug-Related Emergency Department Visits, 2004-2011 - All Visits

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits in New York City (5 boroughs), covering 2004-2011. File includes all drug-related ED visits that are reportable to DAWN without regard for the reason for the visit or the specific drugs involved. It includes visits involving all forms of drug misuse or abuse plus visits resulting from adverse reaction, accidental ingestion, suicide attempts, and visits where patients were seeking detoxification services. These estimates are useful for looking at overall levels of drug involvement in ED visits.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.

Tags: dawn-data, drug-related-ed-visits, nyc-emergency-department, samhsa, substance-abuse-trends
Organization: U.S. Department of Health & Human Services
Compound 527294: 1,3-Di-isobutylmesitylene

Chemical compound data from PubChem database. IUPAC Name: 1,3,5-trimethyl-2,4-bis(2-methylpropyl)benzene. Molecular Formula: C17H28. Molecular Weight: 232.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Region 6, Volume 7

Explore state and regional data for HHS Region 6 with this user-friendly behavioral health report. It uses data from the 2021-2022 National Surveys on Drug Use and Health (NSDUH). The topics addressed in this report include substance use, substance use disorders, and mental health. Selected estimates are provided for adolescents aged 12 to 17, underage people aged 12 to 20, adults aged 18 or older, and the general population aged 12 or older. Statistical tests compare population percentages of (1) HHS region versus national estimates, (2) state versus national estimates, and (3) state versus HHS region estimates.

Tags: behavioral-health, mental-health, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Detroit

Data tables consisting of Excel files with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011, for drug-related emergency department visits for the Detroit Metropolitan Statistical Area. Tables are provided for 10 topics (\"analytic categories\") which are defined in the \"Guide to Drug Abuse Warning Trend Tables,\"  a separate document.   Each table includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol. Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology. Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.

Tags: dawnt-data, detroit-msa, drug-related-ed-visits, samhsa, substance-abuse-trends
Organization: U.S. Department of Health & Human Services
Bone loss: Quantitative imaging techniques for assessing bone mass in rheumatoid arthritis

Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone tissue with clinical manifestation of low trauma fractures. Rheumatoid arthritis (RA) is a risk factor due to generalized and articular bone loss. This minireview presents past and current bone mass measurement techniques in RA. These techniques include: plain radiographs, absorptiometry, quantitative computed tomography (QCT) and ultrasound. The most widely used technique is dual x-ray absorptiometry (DXA). RA patients have lower bone mass as compared with normals and substantial bone loss may occur early after the onset of disease. Measurement of bone mineral density (BMD) at the hand using either DXA or ultrasound maybe a useful tool in the management of RA patients.

Tags: bone-loss, bone-mineral-density, imaging-techniques, nih, rheumatoid-arthritis
Organization: U.S. Department of Health & Human Services
A survey of physicians knowledge regarding awareness of maternal alcohol use and the diagnosis of FAS.

Background
          Alcohol is the most widely used drug in the world that is a human teratogen whose use among women of childbearing age has been steadily increasing. It is also probable that Fetal Alcohol Syndrome is under diagnosed by physicians. The objectives of this study were twofold: 1) to evaluate the experience, knowledge and confidence of family physicians with respect to the diagnosis of FAS and 2) to evaluate physicians awareness of maternal drinking patterns.
        
        
          Methods and Participants
          A multiple choice anonymous questionnaire was sent to a randomly selected group of family physicians in the Metropolitan Toronto area.
        
        
          Results
          There was a 73% (75/103) total response rate; Overall, 6/75 (8%) of family physicians reported that they had actually diagnosed a child with FAS. 17.9% had suspicions but did not make a diagnosis and 12.7% reported making a referral to confirm the diagnosis. Physician rated confidence in the ability to diagnosis FAS was low, with 49% feeling they had very little confidence. 75% reported counselling pregnant women and 60.8% reported counselling childbearing women in general on the use of alcohol. When asked what screening test they used to detect the use of alcohol, 75% described frequency/quantity. Not a single respondent identified using the current accepted screening method for alcohol use (TWEAK) which is recommended by The Centre for Addiction and Mental Health.
        
        
          Conclusions
          Family physicians do not feel confident about diagnosing FAS. None of the physicians were aware of the current screening methods to accurately gage alcohol use in pregnant and childbearing women

Tags: fas-diagnosis, fetal-alcohol-syndrome, maternal-alcohol-use, nih, physician-knowledge
Organization: U.S. Department of Health & Human Services
How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)

Background
          The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy starting with nitrendipine reduces the risk of cardiovascular complications in elderly patients with isolated systolic hypertension. In an attempt to confirm the safety of long-term antihypertensive therapy based on a dihydropyridine, the Syst-Eur patients remained in open follow-up after the end of Syst-Eur 1. This paper presents the second progress report of this follow-up study (Syst-Eur 2). It describes BP control and adherence to study medications.
        
        
          Methods
          After the end of Syst-Eur 1 all patients, treated either actively or with placebo, were invited either to continue or to start antihypertensive treatment with the same drugs as previously used in the active treatment arm. In order to reach the target BP (sitting SBP <150 mmHg), the first line agent, nitrendipine, could be associated with enalapril and/or hydrochlorothiazide.
        
        
          Results
          Of the 3787 eligible patients, 3516 (93%) entered Syst-Eur 2. At the last available visit, 72% of the patients were taking nitrendipine. SBP/DBP at entry in Syst-Eur 2 averaged 160/83 mmHg in the former placebo group and 151/80 mmHg in the former active-treatment group. At the last follow-up visit SBP/DBP in the patients previously randomised to placebo or active treatment had decreased by 16/5 mmHg and 7/5 mmHg, respectively. The target BP was reached by 74% of the patients.
        
        
          Conclusion
          Substantial reductions in systolic BP may be achieved in older patients with isolated systolic hypertension with a treatment strategy starting with the dihydropyridine calcium-channel blocker, nitrendipine, with the possible addition of enalapril and/or hydrochlorothiazide.

Tags: blood-pressure-control, cardiovascular-risk, nih, nitrendipine-treatment, systolic-hypertension
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Rhode Island

This is the 2020 Uniform Reporting System (URS) Output Tables for Rhode Island. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, rhode-island, samhsa
Organization: U.S. Department of Health & Human Services
Compound 525530: (3-Chloro-4-phenylpropoxy-phenyl)-acetic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[3-chloro-4-(2-phenylethoxy)phenyl]acetate. Molecular Formula: C17H17ClO3. Molecular Weight: 304.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase

Background
          Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron technique instead.
        
        
          Results
          In a yeast t-degron (ubiquitin-argDHFRts)- phosphoglycerate mutase (GPM1) fusion strain, increasing periods of exposure to the non-permissive temperature 37°C, even in the presence of cycloheximide, gave decreasing function, as assessed at 23°C in vivo by glucose metabolism and confirmed by immunoblot.
        
        
          Conclusion
          An ideal system would set a range of lower levels of a protein, do so without compensating protein synthesis, and give stable activity for in vitro comparisons. Although the first two aims appear obtainable, the third was not in this example of the application, limiting its uses for some but not all purposes.

Tags: nih, phosphoglycerate-mutase, protein-degradation, t-degron-technique, yeast-protein
Organization: U.S. Department of Health & Human Services
Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling

Background:
          Ventilator-associated bacterial pneumonia (VAP) is a important intensive care unit (ICU)-acquired infection in mechanically ventilated patients. Early and correct diagnosis of VAP is difficult but is an urgent challenge for an optimal antibiotic treatment. The aim of the study was to evaluate the incidence and microbiology of ventilator-associated pneumonia and to compare three quantitative bronchoscopic methods for diagnosis.
        
        
          Methods:
          A prospective, open, epidemiological clinical study was performed in a surgical ICU. In a prospective study, 279 patients admitted to a 14-bed surgical ICU during a 1-year period were evaluated with regard to VAP. Three quantitative culture bronchoscopic techniques for identifying the etiological agent were compared [bronchoalveolar lavage (BAL), protected specimen brush (PSB) and bronchoscopic tracheobronchial secretion (TBS)].
        
        
          Results:
          Among 103 long-term ventilated patients, 49 (48%) developed one or more VAPs (a total of 60 VAPs). The incidence was 24 VAPs per 100 ventilated patients or 23 VAPs per 1000 ventilator days. BAL, PSB and TBS with quantitative measurements were equivalent in identifying the bacterial etiology. The VAP was caused predominantly by Staphylococcus aureus in 38% of cases, followed by Pseudomonas aeruginosa in 10%, Haemophilus influenzae in 10% and Klebsiella sp. in 9%. We did not find an increased mortality rate in patients undergoing long-term ventilation who acquired VAP in comparison with patients without VAP.
        
        
          Conclusion:
          For the identification of the microbiological etiology of VAP, one of three available bronchoscopic methods analysed by quantitative measurements is sufficient. In our study, quantitative bronchoscopic tracheal secretion analysis was very promising. Before accepting this method as a standard technique, other studies will have to confirm our results.

Tags: bronchoalveolar-lavage, bronchoscopic-methods, icu-acquired-infection, nih, ventilator-associated-pneumonia
Organization: U.S. Department of Health & Human Services
Screening for behavioral health in primary care settings: A review of the literature.

The aim of this narrative review was to identify and evaluate publicly available, psychometrically tested tools that primary care providers can use to screen adult patients for common mental and substance use disorders such as depression, anxiety, and alcohol use disorders.Screening for behavioral health in primary care settings: A review of the literature(link is external)

Tags: behavioral-health-screening, mental-health-assessment, primary-care-mental-health, samhsa, substance-use-screening
Organization: U.S. Department of Health & Human Services
West Virginia (WV)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for West Virginia for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh, samhsa, substance-use, west-virginia
Organization: U.S. Department of Health & Human Services
Morgenröthe or business as usual: a personal account of the 2nd Annual EULAR Congress, Prague

The 2nd Annual European League Against Rheumatism (EULAR) Congress, held in Prague, 13–16 June 2001, was an impressive event with a record turnout of 8300 delegates. It offered a large variety of first-class state of the art lectures by some 180 invited worldwide speakers. Several new and ongoing therapeutic developments were discussed. The aim to attract the young scientific community was only partly achieved, and the dependence on industry posed some problems. The organization, however, was a big improvement compared with the previous congress in this series. The number of submitted abstracts was relatively low (1200) compared with the number of delegates. Accommodation of satellite symposia and organization of poster sessions remain problem areas of this meeting. The Annual EULAR Congress emerges as one of the two most important annual congresses of rheumatology, the other being the American College of Rheumatology meeting.

Tags: arthritis-research, eular-congress, nih, rheumatic-diseases, rheumatology-congress
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Federated States Of Micronesia

This is the 2021 Uniform Reporting System (URS) Output Tables for Federated States Of Micronesia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: mental-health-services, micronesia, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Compound 525410: Sulfide, isopropyl pentyl

Chemical compound data from PubChem database. IUPAC Name: 1-propan-2-ylsulfanylpentane. Molecular Formula: C8H18S. Molecular Weight: 146.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Table 17. Alcohol Dependence or Abuse in the Past Year among Persons Aged 12 or Older, by State and Substate Region: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year alcohol dependence or abuse by those aged 12 or older by State and substate regions.

Tags: alcohol-abuse, alcohol-dependence, nsduh, samhsa, substate-data
Organization: U.S. Department of Health & Human Services
Arizona (AZ)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Arizona for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: arizona-survey, illicit-drug-use, mental-health, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Interethnic Adoption Provisions (IEPA) of the Small Business Job Protection Act of 1996

Interethnic Adoption Provisions (IEPA) of the Small Business Job Protection Act of 1996
  
  

 (PDF) - This document provides the text of the Interethnic Adoption Provisions (IEPA) of the Small Business Job Protection Act of 1996.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, law, legal, policy, text
Organization: U.S. Department of Health & Human Services
2016 Uniform Reporting System (URS) Table for Maine

This is the 2016 Uniform Reporting System (URS) Output Tables for Maine. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: mental-health-services, national-outcome-measures, samhsa, substance-abuse, urs-data
Organization: U.S. Department of Health & Human Services