AndreaBozzo/ceres-open-data-index huggingface dataset:
Engaging State Young People in the NYTD Review

This resource provides information to states planning their NYTD Review on why and how a state should involve young people in their NYTD Review process. It discusses ways a state can support young people including providing resources, ideas on how to prepare them, debriefing, networking opportunities, and compensation ideas to incentivize participation.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, child, policy, scope, youth
Organization: U.S. Department of Health & Human Services
VIDA: a virus database system
 for the organization of animal virus genome open reading frames

VIDA is a new virus database that organizes open reading frames
 (ORFs) from partial and complete genomic sequences from animal viruses.
 Currently VIDA includes all sequences from GenBank for Herpesviridae,
 Coronaviridae and Arteriviridae. The ORFs are organized into homologous
 protein families, which are identified on the basis of sequence
 similarity relationships. Conserved sequence regions of potential functional
 importance are identified and can be retrieved as sequence alignments.
 We use a controlled taxonomical and functional classification for
 all the proteins and protein families in the database. When available,
 protein structures that are related to the families have also been
 included. The database is available for online search and sequence
 information retrieval at http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html.

Tags: animal-viruses, nih, open-reading-frames, protein-families, viral-genomes
Organization: U.S. Department of Health & Human Services
Compound 527278: Ortho,meta'-dinitro-diphenylmethane

Chemical compound data from PubChem database. IUPAC Name: 1-nitro-2-[(3-nitrophenyl)methyl]benzene. Molecular Formula: C13H10N2O4. Molecular Weight: 258.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527237: (3S,3aS,6R,7S,8aS)-3,7,8,8-Tetramethyloctahydro-1H-3a,6-methanoazulen-7-ol

Chemical compound data from PubChem database. IUPAC Name: 2,6,6,7-tetramethyltricyclo[6.2.1.01,5]undecan-7-ol. Molecular Formula: C15H26O. Molecular Weight: 222.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
National Directory of Drug and Alcohol Abuse Treatment Facilities - 1994

The National Directory of Drug and Alcohol Abuse Treatment Programs 1994 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 1993 National Survey of Substance Abuse Treatment Services (N-SSATS). The information about each facility that appears in this directory was provided by that facility in response to the 1993 N-SSATS. The Substance Abuse and Mental Health Services Administration (SAMHSA) conducts the N-SSATS annually.

Tags: alcohol-abuse-treatment, n-ssats, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Compound 527289: Pentanoic acid, 4-methyl-, (2E)-3,7-dimethyl-2,6-octadienyl ester

Chemical compound data from PubChem database. IUPAC Name: 3,7-dimethylocta-2,6-dienyl 4-methylpentanoate. Molecular Formula: C16H28O2. Molecular Weight: 252.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Klippel-Feil syndrome – the risk of cervical spinal cord injury: A case report

Background
          Klippel-Feil syndrome is defined as congenital fusion of two or more cervical vertebrae and is believed to result from faulty segmentation along the embryo's developing axis during weeks 3–8 of gestation. Persons with Klippel-Feil syndrome and cervical stenosis may be at increased risk for spinal cord injury after minor trauma as a result of hypermobility of the various cervical segments. Persons with Klippel-Feil Syndrome often have congenital anomalies of the urinary tract as well.
        
        
          Case presentation
          A 51-year male developed incomplete tetraplegia in 1997 when he slipped and fell backwards hitting his head on the floor. X-rays of cervical spine showed fusion at two levels: C2 and C3 vertebrae, and C4 and C5 vertebrae. Intravenous urography (IVU) revealed no kidneys in the renal fossa on both sides, but the presence of crossed, fused renal ectopia in the left ilio-lumbar region. This patient had a similar cervical spinal cord injury about 15 years ago, when he developed transient numbness and paresis of the lower limbs following a fall.
        
        
          Discussion and Conclusion
          1) Persons with Klippel-Feil syndrome should be made aware of the increased risk of sustaining transient neurologic deterioration after minor trauma if there is associated radiographic evidence of spinal stenosis.
          2) Patients with Klippel-Feil syndrome often have congenital anomalies of the urinary tract. Our patient had crossed, fused, ectopia of kidney.
          3) When patients with Klippel-Feil syndrome sustain tetraplegia they have increased chances of developing urinary tract calculi. Treatment of kidney stones may pose a challenge because of associated renal anomalies.
          4) Health professionals caring for cervical spinal cord injury patients with Klippel-Feil syndrome and renal anomalies should place emphasis on prevention of kidney stones. A large fluid intake is recommended for these patients, as a high intake of fluids is still the most powerful and certainly the most economical means of prevention of nephrolithiasis.

Tags: cervical-fusion, klippel-feil-syndrome, nih, renal-ectopia, spinal-cord-injury
Organization: U.S. Department of Health & Human Services
AFCARS Technical Bulletin #20 - Questions and Answers

This webinar was the first session in the AFCARS Final Rule Training Series. This webinar provides an on the overview of Technical Bulletin 20, published October 29, 2020.  It includes a brief description and provides examples for the AFCARS 2020 out-of-home care and adoption and guardianship assistance data elements on the final rule.  It also provided guidance and direction to questions submitted on prior webinars.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, child, data, guidance, policy
Organization: U.S. Department of Health & Human Services
Michigan: 2011-2012 NSDUH

This report presents Michigan\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, michigan-nsduh, samhsa, substance-use, suicidal-ideation
Organization: U.S. Department of Health & Human Services
2019 Uniform Reporting System (URS) Table for Nevada

These are the 2019 Uniform Reporting System (URS) Output Tables for Nevada. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, mental-health-services, national-outcome-measures, nevada, samhsa
Organization: U.S. Department of Health & Human Services
Child Maltreatment 2014 – Data Tables

The Children's Bureau has provided nine data tables in CSV ("Comma Separated Values") file format as an aid to researchers and others who would like to use the data from the Child Maltreatment 2014 report. The provided tables contain basic counts and demographic information that the Children's Bureau believes are of special interest to researchers. These materials are in the public domain and may be reproduced fully or partially without permission of the federal government. The courtesy of attribution is requested. Please note that these tables are a source for the Child Maltreatment 2014 report and if used in research the table name should be changed and we request that source of the data be noted. The recommended citation is provided below:

U.S. Department of Health and Human Services, Administration for Children and Families, Administration on Children, Youth and Families, Children’s Bureau. (2016). Child maltreatment 2014. Available from /cb/research-data-technology/statisti...

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, maltreatment, policy, reporting, scope
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Minnesota

This is the 2020 Uniform Reporting System (URS) Output Tables for Minnesota. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, substance-abuse-mental-health
Organization: U.S. Department of Health & Human Services
AFCARS Report #23

This report provides preliminary estimates of Adoption and Foster Care Analysis and Reporting System (AFCARS) data for FY 2015. As states are permitted to resubmit AFCARS data, the estimates may change over time. This report reflects all AFCARS data received as of June 8, 2016 related to AFCARS reporting periods through September 30, 2015.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, data, foster, policy, reporting
Organization: U.S. Department of Health & Human Services
Table 15. Perceptions of Great Risk of Smoking One or More Packs of Cigarettes Per Day, by Age Group and State: Percentages, Annual Averages Based on 2010 and 2011 NSDUHs

This report presents State estimates for measures of perceptions of great risk of smoking one or more packs of cigarettes per day based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Resuts are provided for youth aged 12 to 17.

Tags: cigarette-smoking, nsduh-data, samhsa, smoking-risk-perception, youth-tobacco-use
Organization: U.S. Department of Health & Human Services
Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection

Background
          Constitutive expression and localization of antimicrobial human β-defensin-1 (HBD-1) in human kidneys as a potential mechanism of antimicrobial defense has been previously reported. Inducible expression of human β-defensin-2 (HBD-2) has been described in various epithelial organs but not for the urogenital tract.
        
        
          Methods
          We investigated the gene- and protein expression of HBD-1 and HBD-2 by reverse transcriptase-polymerase chain reaction, and immunohistochemistry in 15 normal human kidney samples and 15 renal tissues with chronic bacterial infection. Additionally, cell culture experiments were performed to study HBD gene expression by real-time RT-PCR in response to inflammatory cytokines TNFα and IL-1β as well as lipopolysaccharide from Gram-negative bacteria.
        
        
          Results
          Constitutive HBD-1 gene- and protein expression was detected in normal renal tissue and kidneys with chronic infection. As a novel finding, inducible HBD-2 gene- and protein expression was demonstrated in tubulus epithelia with chronic infection but not in normal renal tissue. In pyelonephritic kidneys HBD-1 and HBD-2 expression showed a similar pattern of localizaton in distal tubules, loops of Henle and in collecting ducts of the kidney. Furthermore, real-time RT-PCR of kidney derived cell lines stimulated with inflammatory agents TNF-α, IL-1β and LPS revealed a strong increase in relative HBD-2 transcription level and also a slight increase in relative HBD-1 transcription level.
        
        
          Conclusions
          Upregulated HBD-2 expression in renal tubulus epithelium indicates a role of a wider range of human defensins for antimicrobial host defense in the urogenital tract than previously recognized.

Tags: beta-defensins, gene-expression, kidney-infection, nih, urogenital-tract
Organization: U.S. Department of Health & Human Services
Table 19. Illicit Drug Dependence in the Past Year, by Age Group and State: Percentages, Annual Averages Based on 2013 and 2014 NSDUHs

Table 19. Illicit Drug Dependence in the Past Year, by Age Group and State: Percentages, Annual Averages Based on 2013 and 2014 NSDUHs

Tags: drug-dependence-age, illicit-drug-dependence, nsduh-data, samhsa, substance-use-disorder
Organization: U.S. Department of Health & Human Services
Epidemiology of organic solvents and connective tissue disease

Case reports suggest that solvents are associated with various			 connective tissue diseases (systemic sclerosis, scleroderma, undifferentiated			 connective tissue disease, systemic lupus erythematosis, and rheumatoid			 arthritis), particularly systemic sclerosis. A small number of epidemiological			 studies have shown statistically significant but weak associations between			 solvent exposure, systemic sclerosis, and undifferentiated connective tissue			 disease. However, the interpretation of these positive findings is tempered by			 a lack of replication, an inability to specify which solvents convey risk, and			 an absence of increasing risk with increasing exposure. Existing studies, on			 aggregate, do not show conclusively that solvents (either as a group of			 chemicals or individual chemicals) are causally associated with any connective			 tissue disease. Further investigations should be carried out to replicate the			 positive existing findings and to specify the solvents and circumstances of			 exposure that carry risk.

Tags: connective-tissue-disease, nih, occupational-exposure, organic-solvents, systemic-sclerosis
Organization: U.S. Department of Health & Human Services
First Siena International Conference on Animal Models of Chronic Obstructive Pulmonary Disease, Certosa di Pontignano, University of Siena, Italy, September 30-October 2, 2001

The meeting proved of great interest to those developing an animal model of chronic obstructive pulmonary disease (COPD). COPD is caused by cigarette smoking, evidenced by deterioration in lung function. Lung function is only rarely assessed in animal models. A cigarette smoke driven pathology should provide the best in vivo model for COPD. However, as lesions produced this way take 8–12 months to develop other strategies have to be employed. Emphysematous lesions were also achieved by treatment with elastase, lipopolysaccharide, ozone and other inducers. Several studies described treatments that have shown activity in these models. Transgenic models were discussed, as was the importance of species and strain selection.

Tags: cigarette-smoke-exposure, copd-animal-models, emphysema-models, nih, pulmonary-disease-research
Organization: U.S. Department of Health & Human Services
First Youth Internet Safety Survey (YISS-1)

Results indicate that approximately one in five youth (19%) received a sexual solicitation or approach over the Internet in the last year while one in thirty-three (3%) received an aggressive sexual solicitation where a solicitor asked to meet them somewhere, called them on the telephone, sent them mail, money or gifts.  One in four (25%) had an unwanted exposure to pornography online in the last year.  One in seventeen (6%) youth was threatened or harassed online in the last year.  A small percentage of young people who reported these incidents were distressed by them.  Only a fraction of all episodes were reported to authorities such as a law enforcement agency, an Internet Service Provider, or a hotline.  About one-quarter of the youth who encountered a sexual solicitation or approach told a parent.  About 40% of those reporting an unwanted exposure to pornography told a parent.

Investigators: David Finkelhor, Ph.D.
University of New Hampshire Durham, NH

Kimberly J. Mitchell, Ph.D.
University of New Hampshire Durham, NH

Janis Wolak, J.D.
University of New Hampshire Durham, NH

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Arkansas, 2014

This is a behavioral health report for the state of Arkansas. It uses the National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use, youth mental health and treatment, adult mental health and treatment, substance use, and substance use treatment for the years 2009 to 2013.

Tags: arkansas-behavioral-health, mental-health-arkansas, samhsa, substance-use-arkansas, youth-mental-health
Organization: U.S. Department of Health & Human Services
Florida (FL)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Florida overall and for substate regions within Florida. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).

Tags: alcohol-abuse, mental-health-florida, nsduh-data, samhsa, substance-use-disorder
Organization: U.S. Department of Health & Human Services
2012-2014 NSDUH Substate Region Estimates – Excel Tables and CSV Files

Prevalence estimates for 25 measures of substance use and mental illness are provided along with 95% confidence intervals for persons aged 12 or older for the substance use measures, persons aged 18 or older for the mental illness measures, and persons aged 12-20 for two alcohol measures.

Tags: mental-illness, nsduh-data, prevalence-estimates, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Thrombocytopenia in critically ill surgical patients: a case-control
		  study evaluating attributable mortality and transfusion requirements

Background:
          That thrombocytopenia results in increased mortality or
				transfusion requirements has not been confirmed by previous studies. We
				performed a case-control study in which 36 patients who developed severe
				thrombocytopenia of less than 50×109 platelets/l were carefully
				matched for the severity of underlying disease and other important
				variables.
        
        
          Results:
          Seventeen (47%) thrombocytopenic patients died, versus 10 (28%)
				matched control patients who were not thrombocytopenic.Nine pairs had a
				discordant outcome, and in eight of these pairs the thrombocytopenic patient
				died (exact binomial probability 0.037). The estimated attributable mortality
				was 19.5% (95% confidence interval 3.2⌓35.8), and the estimated odds ratio was
				2.7 (95% confidence interval 1.02⌓7.10). Thrombocytopenic patients had
				comparable values for severity of illness scores between day of admission and
				day of thrombocytopenia, in contrast with control patients who had a
				statistically significant decrease in severity of illness scores during the
				same period. Thirty (83%) of the thrombocytopenic patients required transfusion
				of blood products, versus 21 (58%) control patients (paired χ2
				test 4.92, P < 0.04). The estimated attributable transfusion
				requirement was 25% (95% confidence interval 5.4⌓44.6), and the estimated odds
				ratio was 1.52 (95 confidence interval 1.05⌓2.20).
        
        
          Conclusion:
          The present study suggests that thrombocytopenia of less than
				50 × 109 platelets/l may be a marker for more severe illness and
				increased risk of death, rather than causative, because a true causal
				relationship is not established. Thrombocytopenia also leads to an excess of
				blood product consumption.

Tags: case-control-study, nih, surgical-icu, thrombocytopenia-mortality, transfusion-requirements
Organization: U.S. Department of Health & Human Services
NSDUH 2019 Sample Experience Report

The goal of this report is to further document the 2019 NSDUH sample experiences, including a comparison of actual sample yields to state and quarter targets, a comparison of achieved and expected design effects (DEFFs) and relative standard errors, and documentation of any issue encountered during sample implementation. The 2019 sample design is thoroughly documented in the 2019 NSDUH sample design report (Center for Behavioral Health Statistics and Quality, 2020).

Tags: design-effects, nsduh-2019, samhsa, sample-design, survey-methodology
Organization: U.S. Department of Health & Human Services
Table 18. 2011-2012 NSDUH Illicit Drug Dependence or Abuse in the Past Year, by Age Group and State

Table 18. Illicit Drug Dependence or Abuse in the Past Year, by Age Group and State: Percentages, Annual Averages Based on 2011 and 2012 NSDUHs. Results are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: drug-abuse, drug-dependence, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services