AndreaBozzo/ceres-open-data-index huggingface dataset:
Behavioral Health Barometer: Oregon, 2014

This is a behavioral health report for the state of Oregon. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment, and medicare enrollees for the years 2009 to 2013.

Tags: mental-health-oregon, oregon-behavioral-health, samhsa, substance-use-oregon, youth-mental-health
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for Federated States of Micronesia

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Federated States of Micronesia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, micronesia, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Design and implementation of microarray gene expression markup language (MAGE-ML)

Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same format from one publication to another. MAGE will help microarray data producers and users to exchange information by providing a common platform for data exchange, and MAGE-STK will make the adoption of MAGE easier.

Tags: data-exchange, gene-expression, mage-ml, microarray-data, nih
Organization: U.S. Department of Health & Human Services
Comparison of 2009-2010 and 2010-2011 prevalence estimates for persons aged 12 or older, 12 to 17, 18 to 25, and 26 or older (26 tables)

This report presents trends of estimates for measures of substance use and mental health based on the combined  2009 and 2010 and the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh, prevalence-estimates, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
2013 CMHS Uniform Reporting System (URS) Tables for Minnesota

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Minnesota for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Compound 525482: 4-Methyl-5-oxo-1,2-dithia-3-cyclopentene

Chemical compound data from PubChem database. IUPAC Name: 5-methyloxadithiole. Molecular Formula: C3H4OS2. Molecular Weight: 120.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Update: Emergency Department Visits for Adverse Reactions to Medications among Children Aged 12 or Younger

This Drug Abuse Warning Network (DAWN) data spotlight uses 2011 data to examine ED visits for adverse reactions to medications among children aged 12 or younger.

Tags: dawn-data, emergency-department-visits, medication-side-effects, pediatric-adverse-drug-events, samhsa
Organization: U.S. Department of Health & Human Services
2007 Mental Health National Outcome Measures (NOMS): CMHS Uniform Reporting System

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2007. The URS is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State mental health authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures, providing an overview of state mental health delivery systems.

Tags: behavioral-health, mental-health-services, outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Virginia, 2014

This is a behavioral health report for the state of Virginia. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment, and medicare enrollees for the years 2009 to 2013.

Tags: adult-mental-health, samhsa, substance-use-trends, virginia-behavioral-health, youth-mental-health
Organization: U.S. Department of Health & Human Services
2012 State Profile - Massachusetts

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) annual report showing the state profile for Massachusetts in 2012. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: behavioral-health-services, massachusetts, n-ssats, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
A prospective, cross-sectional study of anaemia and peripheral iron status in antiretroviral naïve, HIV-1 infected children in Cape Town, South Africa

Background
          Anaemia is a common manifestation of paediatric HIV infection. Although there are many causes, anaemia of chronic diseases is the most frequent type. In poor countries iron deficiency is widespread. It is probable that many HIV-infected children in these countries are also iron deficient. This study describes the relationship between paediatric HIV infection and anaemia, and documents the peripheral iron status of antiretroviral naive, HIV-infected children.
        
        
          Methods
          Sixty children were evaluated prospectively. Investigations included CD4+ count, haemoglobin concentration (Hb), red blood cell (RBC) morphology, and iron studies.
        
        
          Results
          Anaemia was present in 73% of children. Compared to mild HIV infection, median Hb was lower in children with moderate clinical infection (104 g/L v 112 g/L, p = 0.04) and severe clinical infection (96 g/L v 112 g/L, p = 0.006), and more children with severe infection were anaemic (92% v 58%, 0.04). There was a significant relationship between immunological status and Hb. 68% had abnormal RBC morphology. Significantly more children with moderate and severe disease, and severe immunosuppression had abnormal RBC morphology. 52% were iron-depleted, 20% had iron-deficient erythropoiesis and 18% iron deficiency anaemia (IDA). 16% (7/44) of anaemic children had microcytosis and hypochromia. Median soluble transferrin receptor concentration was significantly higher in those with microcytic hypochromic anaemia (42.0 nmol/L v 30.0 nmol/L, p = 0.008).
        
        
          Conclusions
          Both the proportion of anaemic children and the median Hb were associated with disease status. Iron depletion and IDA are major problems in HIV-infected children in South Africa.

Tags: antiretroviral-naive, child-anemia, iron-status, nih, pediatric-hiv
Organization: U.S. Department of Health & Human Services
Interactions of pathogens and irritant chemicals in land-applied sewage sludges (biosolids)

Background
          Fertilisation of land with processed sewage sludges, which often contain low levels of pathogens, endotoxins, and trace amounts of industrial and household chemicals, has become common practice in Western Europe, the US, and Canada. Local governments, however, are increasingly restricting or banning the practice in response to residents reporting adverse health effects. These self-reported illnesses have not been studied and methods for assessing exposures of residential communities to contaminants from processed sewage sludges need to be developed.
        
        
          Methods
          To describe and document adverse effects reported by residents, 48 individuals at ten sites in the US and Canada were questioned about their environmental exposures and symptoms. Information was obtained on five additional cases where an outbreak of staphylococcal infections occurred near a land application site in Robesonia, PA. Medical records were reviewed in cases involving hospitalisation or other medical treatment. Since most complaints were associated with airborne contaminants, an air dispersion model was used as a means for potentially ruling out exposure to sludge as the cause of adverse effects.
        
        
          Results
          Affected residents lived within approximately 1 km of land application sites and generally complained of irritation (e.g., skin rashes and burning of the eyes, throat, and lungs) after exposure to winds blowing from treated fields. A prevalence of Staphylococcus aureus infections of the skin and respiratory tract was found. Approximately 1 in 4 of 54 individuals were infected, including 2 mortalities (septicaemia, pneumonia). This result was consistent with the prevalence of S. aureus infections accompanying diaper rashes in which the organism, which is commonly found in the lower human colon, tends to invade irritated or inflamed tissue.
        
        
          Conclusions
          When assessing public health risks from applying sewage sludges in residential areas, potential interactions of chemical contaminants with low levels of pathogens should be considered. An increased risk of infection may occur when allergic and non-allergic reactions to endotoxins and other chemical components irritate skin and mucus membranes and thereby compromise normal barriers to infection.

Tags: biosolids-exposure, environmental-health, nih, sewage-sludge, staphylococcal-infections
Organization: U.S. Department of Health & Human Services
2011 CMHS Uniform Reporting System (URS) Output Tables for Montana

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, community-mental-health, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Table 14. Cigarette Use in the Past Month, by Age Group and State: Percentages, Annual Averages Based on 2010 and 2011 NSDUHs

This report presents State estimates for measures of past month cigarette use based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Resuts are provided by age group.

Tags: cigarette-use, samhsa, state-level-data, tobacco-use, youth-smoking
Organization: U.S. Department of Health & Human Services
Compound 525228: Chloromethyl heptanoate

Chemical compound data from PubChem database. IUPAC Name: chloromethyl heptanoate. Molecular Formula: C8H15ClO2. Molecular Weight: 178.65. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Novel memory mutants in

Background
          Starting from Benzer's initiative, the approach of forward genetics has been widely used to isolate mutations affecting learning and memory. For this aim, mainly the odor-shock conditioning was employed. We have isolated P insertional mutations affecting memory after courtship conditioning – another form of classical conditioning in Drosophila. Here we report the behavioral characteristics of one of these mutants, which we have called nemy (no extended memory).
        
        
          Results
          The courtship activity of Drosophila males is reduced when a male has a previous experience of courting a fertilized female. In the wild-type strain C-S (K), this conditioned courtship inhibition lasts for 1–3 h in the test with a virgin female, and at least for 8 h in the test with a subsequent fertilized female. The mutant males nemyP153 display distinct memory deficiency in both tests already 0.5 h after training. The mutant males show an increased level of locomotor activity unrelated to courtship, and spend more time in such an element of courtship as pursuit. This, however, seems to be a pleiotropic effect of the mutation, independent from its influence on the courtship conditioning. The mutation reduces also memory performance after the odor-shock classical conditioning. At the same time, the sensory and motor functions involved in this type of learning seem to be normal.
        
        
          Conclusions
          Insertion of P-lacW vector into 49B region of the second chromosome (mutation nemyP153) causes an increased level of locomotor activity, memory deficiency after the courtship conditioning and subnormal acquisition after the odor-shock conditioning.

Tags: behavioral-genetics, courtship-conditioning, drosophila-melanogaster, memory-mutants, nih
Organization: U.S. Department of Health & Human Services
Compound 528455: 1-Octadecene, 4,9,13,17-tetramethyl

Chemical compound data from PubChem database. IUPAC Name: 4,9,13,17-tetramethyloctadec-1-ene. Molecular Formula: C22H44. Molecular Weight: 308.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Treatment Episode Data Set (TEDS): 2015, National Discharge from Substance Abuse Treatment Services

This report presents data from the Treatment Episode Data Set (TEDS) for discharges from treatment in 2015. It is a companion to the reports Treatment Episode Data Set (TEDS): 2005-2015 National Admissions to Substance Abuse Treatment and Treatment Episode Data Set (TEDS): 2005-2015 State Admissions to Substance Abuse Treatment. These reports provide information on the demographic and substance abuse characteristics of substance abuse treatment admissions and discharges aged 12 and older in facilities that report to individual state administrative data systems. In addition, characteristics used to analyze changes from admission to discharge among the linked admission and discharge records are included. Primary substance of abuse, frequency of use, and employment status at admission are repeated in several tables. This is done so that characteristics at admission and discharge can be appropriately compared with each other and to ensure the inclusion of important data that might otherwise be overlooked.

Tags: addiction-treatment, samhsa, substance-abuse-treatment, teds, treatment-discharge-data
Organization: U.S. Department of Health & Human Services
Frailty, fitness and late-life mortality in relation to chronological and biological age

Background
          People age at remarkably different rates, but how to estimate trajectories of senescence is controversial.
        
        
          Methods
          In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) we estimated a frailty index based on the proportion of 20 deficits observed in a structured clinical examination. The construct validity of the index was examined through its relationship to chronological age (CA). The criterion validity was examined in its ability to predict mortality, and in relation to other predictions about aging. From the frailty index, relative (to CA) fitness and frailty were estimated, as was an individual's biological age.
        
        
          Results
          The average value of the frailty index increased with age in a log-linear relationship (r = 0.91; p < 0.001). In a Cox regression analysis, biological age was significantly more highly associated with death than chronological age. The average increase in the frailty index (i.e. the average accumulation of deficits) amongst those with no cognitive impairment was 3 per cent per year.
        
        
          Conclusions
          The frailty index is a sensitive predictor of survival. As the index includes items not traditionally related to adverse health outcomes, the finding is compatible with a view of frailty as the failure to integrate the complex responses required to maintain function.

Tags: biological-age, frailty-index, late-life-mortality, nih, senescence
Organization: U.S. Department of Health & Human Services
A simple method for serving Web hypermaps with dynamic database drill-down

Background
          HealthCyberMap  aims at mapping parts of health information cyberspace in novel ways to deliver a semantically superior user experience. This is achieved through "intelligent" categorisation and interactive hypermedia visualisation of health resources using metadata, clinical codes and GIS. HealthCyberMap is an ArcView 3.1 project. WebView, the Internet extension to ArcView, publishes HealthCyberMap ArcView Views as Web client-side imagemaps. The basic WebView set-up does not support any GIS database connection, and published Web maps become disconnected from the original project. A dedicated Internet map server would be the best way to serve HealthCyberMap database-driven interactive Web maps, but is an expensive and complex solution to acquire, run and maintain. This paper describes HealthCyberMap simple, low-cost method for "patching" WebView to serve hypermaps with dynamic database drill-down functionality on the Web.
        
        
          Results
          The proposed solution is currently used for publishing HealthCyberMap GIS-generated navigational information maps on the Web while maintaining their links with the underlying resource metadata base.
        
        
          Conclusion
          The authors believe their map serving approach as adopted in HealthCyberMap has been very successful, especially in cases when only map attribute data change without a corresponding effect on map appearance. It should be also possible to use the same solution to publish other interactive GIS-driven maps on the Web, e.g., maps of real world health problems.

Tags: gis-data, health-information, hypermedia-visualization, interactive-maps, nih
Organization: U.S. Department of Health & Human Services
Compound 525339: 1,1,3-Tris(methylthio)propane

Chemical compound data from PubChem database. IUPAC Name: 1,1,3-tris(methylsulfanyl)propane. Molecular Formula: C6H14S3. Molecular Weight: 182.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Preliminary Findings from Drug-Related Emergency Department Visits, 2021

Preliminary Findings from Drug-Related Emergency Department Visits, 2021. An analysis of 2021 preliminary data presents (1) nationally representative weighted estimates for the top five drugs in drug-related ED visits, (2) the assessment of monthly trends and drugs involved in polysubstance ED visits in a subset of sentinel hospitals, and (3) the identification of drugs new to DAWN’s Drug Reference Vocabulary.https://store.samhsa.gov/sites/default/files/SAMHSA_Digital_Download/PEP22-07-03-001.pdf

Tags: drug-related-ed-visits, emergency-department, polysubstance-use, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location

Background
          Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells. A human RNase III orthologue has been implicated in ribosomal RNA maturation. To better understand the structure and mechanism of mammalian RNase III and its involvement in RNA metabolism we determined the cDNA structure, chromosomal location, and expression patterns of mouse RNase III.
        
        
          Results
          The predicted mouse RNase III polypeptide contains 1373 amino acids (~160 kDa). The polypeptide exhibits a single C-terminal dsRNA-binding motif (dsRBM), tandem catalytic domains, a proline-rich region (PRR) and an RS domain. Northern analysis and RT-PCR reveal that the transcript (4487 nt) is expressed in all tissues examined, including extraembryonic tissues and the midgestation embryo. Northern analysis indicates the presence of an additional, shorter form of the transcript in testicular tissue. Fluorescent in situ hybridization demonstrates that the mouse RNase III gene maps to chromosome 15, region B, and that the human RNase III gene maps to a syntenic location on chromosome 5p13-p14.
        
        
          Conclusions
          The broad transcript expression pattern indicates a conserved cellular role(s) for mouse RNase III. The putative polypeptide is highly similar to human RNase III (99% amino acid sequence identity for the two catalytic domains and dsRBM), but is distinct from other eukaryotic orthologues, including Dicer, which is involved in RNA interference. The mouse RNase III gene has a chromosomal location distinct from the Dicer gene.

Tags: cdna-structure, gene-expression, nih, ribonuclease-iii, rna-metabolism
Organization: U.S. Department of Health & Human Services
Trend Tables (Standard Errors and P Values) - 7.1 to 7.45

These detailed tables show standard errors for trends in totals and prevalence estimates of illicit drug use, risk and protective factors, substance initiation, substance dependence/abuse, and need/receipt of substance use treatment from the 2011 National Survey on Drug Use and Health (NSDUH). Substances examined include illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens (including LSD, PCP, Ecstasy, Ketamine, DMT/AMT/Foxy, Salvia divinorum), inhalants, and the nonmedical use of prescription-type pain relievers (including OxyContin), tranquilizers, stimulants (Adderall), sedatives (GHB, Ambien), non-prescription cold medicine, alcohol, and tobacco products (including cigarettes, smokeless tobacco, cigars, pipes). Standard errors are provided for totals and estimates of lifetime, past year, and past month use by age group, gender, race/ethnicity, education level, employment status, and geographic area.

Tags: drug-trends, nsduh-data, samhsa, standard-errors, substance-use
Organization: U.S. Department of Health & Human Services