AndreaBozzo/ceres-open-data-index huggingface dataset:
Assessment of the infectious diseases surveillance system of the Republic of Armenia: an example of surveillance in the Republics of the former Soviet Union

Background
          Before 1991, the infectious diseases surveillance systems (IDSS) of the former Soviet Union (FSU) were centrally planned in Moscow. The dissolution of the FSU resulted in economic stresses on public health infrastructure. At the request of seven FSU Ministries of Health, we performed assessments of the IDSS designed to guide reform. The assessment of the Armenian infectious diseases surveillance system (AIDSS) is presented here as a prototype.
        
        
          Discussion
          We performed qualitative assessments using the Centers for Disease Control and Prevention (CDC) guidelines for evaluating surveillance systems. Until 1996, the AIDSS collected aggregate and case-based data on 64 infectious diseases. It collected information on diseases of low pathogenicity (e.g., pediculosis) and those with no public health intervention (e.g., infectious mononucleosis). The specificity was poor because of the lack of case definitions. Most cases were investigated using a lengthy, non-disease-specific case-report form Armenian public health officials analyzed data descriptively and reported data upward from the local to national level, with little feedback. Information was not shared across vertical programs. Reform should focus on enhancing usefulness, efficiency, and effectiveness by reducing the quantity of data collected and revising reporting procedures and information types; improving the quality, analyses, and use of data at different levels; reducing system operations costs; and improving communications to reporting sources. These recommendations are generalizable to other FSU republics.
        
        
          Summary
          The AIDSS was complex and sensitive, yet costly and inefficient. The flexibility, representativeness, and timeliness were good because of a comprehensive health-care system and compulsory reporting. Some data were questionable and some had no utility.

Tags: armenia, infectious-disease, nih, public-health, surveillance-system
Organization: U.S. Department of Health & Human Services
Funding Opportunity Announcement for Tribal Title IV-E Plan Development Grants

The Children’s Bureau (CB), within the Administration for Children and Families (ACF), held two Tribal consultation calls to discuss a forthcoming funding opportunity announcement (FOA). CB is seeking input from Tribal leaders to ensure these opportunities are designed in a well-informed and culturally responsive way to best position for success.

The Standing Announcement for Tribal Title IV-E Plan Development Grants
  
  

 (HHS-2016-ACF-ACYF-CS-1176)

The purpose of the FOA is to solicit proposals for one-time grants to Tribes, Tribal organizations, or Tribal consortia that are seeking to develop and, within 24 months of grant receipt, submit to the Department of Health and Human Services a plan to implement a title IV-E foster care, adoption assistance, and, at Tribal option, guardianship assistance program. Grant funds under this FOA may be used for the cost of developing a title IV-E plan under section 471 of the Social Security Act (the Act) to carry out a program under section 479B of the Act. The grant may be used for costs relating to the development of case planning and case review systems, foster care licensing and standards for Tribal foster homes and child care facilities, quality assurance systems, court structure and procedures, data collection systems, cost allocation methodology development, financial controls and financial management processes, or any other costs attributable to meeting any other requirement necessary for approval of a title IV-E plan.

Please submit all written comments to the Children’s Bureau at TribalFOA@acf.hhs.gov. We’ve been experiencing some problems with that email address, so please copy your written comments to Eileen West’s email address: eileen.west@acf.hhs.gov.

CB held Tribal consultation calls to discuss this funding opportunity on two dates, Tuesday, March 8, 2016 and Thursday, March 10, 2016. Both calls were held at 2:00 pm Eastern Standard Time and were recorded. The audio and transcript files are available for download below.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, cross, fiscal, grant, policy
Organization: U.S. Department of Health & Human Services
1.5 Million Adults Have Serious Mental Illness and Misused Opioids In the Past Year

This spotlight uses the 2015 National Survey on Drug Use and Health to examine the relationship between serious mental illness and past year opioid use among adults aged 18 or older.

Tags: comorbidity, nsduh-data, opioid-misuse, samhsa, serious-mental-illness
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Republic of Marshall Islands

This is the 2021 Uniform Reporting System (URS) Output Tables for Republic of Marshall Islands. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, republic-marshall-islands, samhsa
Organization: U.S. Department of Health & Human Services
2021-2022 NSDUH: Older Adult Behavioral Health

Find key substance use, mental health, and treatment indicators among adults aged 60 or older in the United States. Estimates were based on combined data from the 2021 and 2022 National Surveys on Drug Use and Health (NSDUH).

Tags: behavioral-health, mental-health, older-adults, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Table 20. Illicit Drug Dependence in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 20. Illicit Drug Dependence in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Tags: adolescent-drug-use, illicit-drug-dependence, nsduh-survey, samhsa, substance-use-disorder
Organization: U.S. Department of Health & Human Services
Genetics of rheumatoid arthritis: confronting complexity

The genetic basis for rheumatoid arthritis (RA) is likely to be			 extremely complex. Even the role of MHC genes remains to be fully defined, and			 may involve interactive genetic effects. The difficulty of precisely defining			 the clinical phenotype, as well as underlying genetic heterogeneity,			 complicates the problem. In addition, stochastic genetic or physiologic events			 may contribute to the low penetrance of susceptibility genes. This situation			 parallels developing paradigms for other autoimmune disorders, in which many			 different genes each appear to contribute a small amount to overall risk for			 disease, and where severity and specific phenotypic subtypes are subject to			 genetic effects. The completion of the human genome project, along with			 advances in informatics, will be required to reach a deeper understanding of			 RA. It is likely that this will involve an iterative and interactive process			 between several different scientific disciplines.

Tags: autoimmune-disorders, genetic-susceptibility, mhc-genes, nih, rheumatoid-arthritis
Organization: U.S. Department of Health & Human Services
Confounding factors in diagnosing brain death: a case report

Background
          Brain death is strictly defined medically and legally. This diagnosis depends on three cardinal neurological features: coma, absent brainstem reflexes, and apnea. The diagnosis can only be made, however, in the absence of intoxication, hypothermia, or certain medical illnesses.
        
        
          Case presentation
          A patient with severe hypoxic-ischemic brain injury met the three cardinal neurological features of brain death but concurrent profound hypothyroidism precluded the diagnosis. Our clinical and ethical decisions were further challenged by another facet of this complex case. Although her brain damage indicated a hopeless prognosis, we could not discontinue care based on futility because the only known surrogate was mentally retarded and unable to participate in medical planning.
        
        
          Conclusion
          The presence of certain medical conditions prohibits a diagnosis of brain death, which is a medicolegal diagnosis of death, not a prediction or forecast of future outcome. While prognostication is important in deciding to withdraw care, it is not a component in diagnosing brain death.

Tags: brain-death, brain-death-diagnosis, hypothyroidism, hypoxic-ischemic-brain-injury, nih
Organization: U.S. Department of Health & Human Services
Missouri (MO)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Missouri for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, missouri, nsduh, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
The NSDUH Report: Trends in Cigarette Use among Adolescents and Young Adults

This report uses 2004 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past month cigarette use among adolescents aged 12 to 17 and young adults aged 18 to 25 and the number of cigarettes smoked among daily smokers in these populations. Results are shown by year.

Tags: adolescent-smoking, cigarette-use-trends, nsduh-survey, samhsa, young-adult-smoking
Organization: U.S. Department of Health & Human Services
Jejunogastric intussusception presented with hematemesis: a case presentation and review of the literature

Background
          Jejunogastric intussusception (JGI) is a rare but potentially very serious complication of gastrectomy or gastrojejunostomy. To avoid mortality early diagnosis and prompt surgical intervention is mandatory.
        
        
          Case presentation
          A young man presented with epigastric pain and bilous vomiting followed by hematemesis,10 years after vagotomy and gastrojejunostomy for a bleeding duodenal ulcer. Emergency endoscopy showed JGI and the CT scan of the abdomen was compatible with this diagnosis. At laparotomy a retrograde type II, JGI was confirmed and managed by reduction of JGI without intestinal resection. Postoperative recovery was uneventful.
        
        
          Conclusions
          JGI is a rare condition and less than 200 cases have been published since its first description in 1914. The clinical picture is almost diagnostic. Endoscopy performed by someone familiar with this rare entity is certainly diagnostic and CT-Scan of the abdomen could also help. There is no medical treatment for acute JGI and the correct treatment is surgical intervention as soon as possible.

Tags: case-report, gastrojejunostomy, hematemesis, jejunogastric-intussusception, nih
Organization: U.S. Department of Health & Human Services
2017-2018 National Survey on Drug Use and Health National Maps of Prevalence Estimates, by State

The 116 national maps presented here show the 2017-2018 National Survey on Drug Use and Health (NSDUH) estimates for 30 substance use and mental health outcomes, by age group, for 50 states and the District of Columbia.

Tags: mental-health, prevalence-estimates, samhsa, state-level-data, substance-use
Organization: U.S. Department of Health & Human Services
Los Angeles Times Poll, 1985

This opinion study was designed to determine the prevalence of childhood sexual abuse among a national sample of adult men and women and to identify characteristics of victims and risk factors associated with childhood sexual victimization. The sampling frame included all residential telephones in the United States.  2,629 men and women 18 years or older were contacted by telephone during an eight day period in July of 1985.  Knowledge and attitudes about sexual abuse were ascertained and information was gathered about the respondents' personal life circumstances.

Investigators: Lewis, I.A.

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
Oregon (OR)

This report presents Oregon\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Oregon for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh-data, oregon-survey, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
2013 CMHS Uniform Reporting System (URS) Tables for Florida

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Tables for Florida for 2013. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program.  State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: florida-mental-health, mental-health-services, noms-data, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
South Dakota: 2011-2012 NSDUH

This report presents South Dakota\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh-data, samhsa, south-dakota, substance-use
Organization: U.S. Department of Health & Human Services
Rational therapy of chronic venous insufficiency – chances and limits of the therapeutic use of horse-chestnut seeds extract

Background and methods
          We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both, compression therapy and oral therapy with horse-chestnut seeds extracts (HCSE) were compared to placebo.
        
        
          Results
          The published study in early CVI (Grade I) showed HCSE and compression to be superior to placebo and to be equivalent to each other in reducing lower leg volume, a measure for oedema.
          In the study, in advanced CVI (Grade II and IIIa), compression appeared to be superior to placebo, whereas HCSE was not. HCSE fared better in Grade II than in Grade IIIa patients.
          These results are discussed in the light of data from an in vitro model, where HCSE has been able to close the intercellular gaps in the venular endothelium. Not fully specified factors lead to an opening of these gaps, resulting in oedema as well as in local coagulation and thrombosis. The subsequent inflammation keeps these gaps open and initiates and maintains a chronic disease process, which may be the starting point of CVI.
        
        
          Conclusion
          Due to its ability to close the venular endothelial gaps, HCSE seems to be a suitable and protecting therapy during the early stages of CVI. In later more severe stages compression therapy is indicated. Taking into account the observed negative impact of compression on quality of life, pharmacological CVI therapy should start early to avoid progress and to spare patients compression therapy.

Tags: chronic-venous-insufficiency, compression-therapy, horse-chestnut-extract, lower-leg-edema, nih
Organization: U.S. Department of Health & Human Services
Debate: When should we intervene in unstable angina - Time for an old look?

Current treatment modalities for patients with acute coronary syndromes center on early diagnosis, risk stratification and, increasingly, early treatment including invasive approaches. The appropriate timing of these invasive modalities in the context of the overall treatment program remains an area of controversy. Specifically, studies in the past recommended a period of medical 'stabilization' while current approaches are considerably more aggressive. The potential hazard of early intervention, in particular, has not properly been weighed against the benefit. This article hopes to provide a framework for examining the appropriate timing of intervention, specifically percutaneous coronary intervention, in acute coronary syndromes.

Tags: acute-coronary-syndrome, early-intervention, nih, percutaneous-coronary-intervention, unstable-angina
Organization: U.S. Department of Health & Human Services
Supporting Evidence-Based Home Visitation Programs to Prevent Child Abuse and Neglect Project: The Illinois Department of Human Services

Location:

Statewide

Home Visiting Program Selected:

Nurse Family Partnership, Healthy Families America, and Parents as Teachers

Home Visiting Target Population:

Families at risk for child maltreatment, including first-time parents and parents who have recently added a newborn to their family

Project Overview:
The Illinois Department of Human Services will lead development of an integrated state infrastructure to support three evidence-based models of home visitation. Illinois DHS will coordinate with two other state agencies, Illinois Department of Children and Family Services and Illinois State Board of Education, and with service providers and advocacy groups in the state. Grant goals are to: 1) create a successful and sustainable state level collaborative to support Healthy Families Illinois, Parents as Teachers, and Nurse Family Partnership programs; 2) ensure that local home visiting programs are effective in reducing the risk for child abuse or neglect (implemented and operated with fidelity to the original model) through a quality assurance approach that includes training, technical assistance, monitoring, data collection, reporting and credentialing; and 3) conduct a rigorous evaluation to demonstrate that Illinois' home visitation infrastructure is effective and efficient. The evaluation will examine implementation of the state infrastructure, measure improvements in the operation and impact of local programs, and gauge the impact of these programs on parent-child interactions and the occurrence of child maltreatment.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, intervention, maltreatment, neglect, prevention
Organization: U.S. Department of Health & Human Services
Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens

Background
          In learning and memory tasks, requiring visual spatial memory (VSM), males exhibit superior performance to females (a difference attributed to the hormonal influence of estrogen). This study examined the influence of phytoestrogens (estrogen-like plant compounds) on VSM, utilizing radial arm-maze methods to examine varying aspects of memory. Additionally, brain phytoestrogen, calbindin (CALB), and cyclooxygenase-2 (COX-2) levels were determined.
        
        
          Results
          Female rats receiving lifelong exposure to a high-phytoestrogen containing diet (Phyto-600) acquired the maze faster than females fed a phytoestrogen-free diet (Phyto-free); in males the opposite diet effect was identified. In a separate experiment, at 80 days-of-age, animals fed the Phyto-600 diet lifelong either remained on the Phyto-600 or were changed to the Phyto-free diet until 120 days-of-age. Following the diet change Phyto-600 females outperformed females switched to the Phyto-free diet, while in males the opposite diet effect was identified.
          Furthermore, males fed the Phyto-600 diet had significantly higher phytoestrogen concentrations in a number of brain regions (frontal cortex, amygdala & cerebellum); in frontal cortex, expression of CALB (a neuroprotective calcium-binding protein) decreased while COX-2 (an inducible inflammatory factor prevalent in Alzheimer's disease) increased.
        
        
          Conclusions
          Results suggest that dietary phytoestrogens significantly sex-reversed the normal sexually dimorphic expression of VSM. Specifically, in tasks requiring the use of reference, but not working, memory, VSM was enhanced in females fed the Phyto-600 diet, whereas, in males VSM was inhibited by the same diet. These findings suggest that dietary soy derived phytoestrogens can influence learning and memory and alter the expression of proteins involved in neural protection and inflammation in rats.

Tags: nih, phytoestrogens-effects, radial-arm-maze, sex-differences, spatial-memory
Organization: U.S. Department of Health & Human Services
Compound 525548: N-Benzylidene-3-bromoaniline

Chemical compound data from PubChem database. IUPAC Name: N-(3-bromophenyl)-1-phenylmethanimine. Molecular Formula: C13H10BrN. Molecular Weight: 260.13. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528405: 2-Ethyl-4-methyloxazole

Chemical compound data from PubChem database. IUPAC Name: 2-ethyl-4-methyl-1,3-oxazole. Molecular Formula: C6H9NO. Molecular Weight: 111.14. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Formative Evaluation Toolkit

This toolkit, which is primarily intended for child welfare agencies and professionals to use in partnership with their evaluators, introduces the concept of formative evaluation, a method for evaluating programs during early implementation in order to inform program improvement and assess readiness for rigorous summative evaluation.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, child, policy, scope, social
Organization: U.S. Department of Health & Human Services