AndreaBozzo/ceres-open-data-index huggingface dataset:
Patent AT-E401751-T1: [Translated] CUSTOM MESSAGES BETWEEN A WIRELESS ACCESS POINT AND SERVICES

A method is disclosed for facilitating the preparation of customized messaging between a wireless access point and a variety of service platforms. The wireless access point includes a registry of trigger words, each word specifying the particular events that must be detected by the access point upon receiving a packet from a mobile wireless device, in order to invoke the process of sending a corresponding server message to a selected server. When the wireless packet is received by the access point, the access point uses the various types of information in the received packet as stimuli to be matched with the trigger words stored in the trigger word registry. If there is a match, then a customized message corresponding to the matched trigger word is accessed from a customized message registry and sent to the server specified in the message. The server uses this information for an appropriate query of its database to access the content. The content is then used for a particular application or returned to the access point for communication to the mobile device. The wireless access point includes management software to present to the system administrator on a connected personal computer, a management menu of example trigger words and example server messages. The management software provides an editor to enable the administrator to optionally customize the example trigger words and/or server messages to suit particular applications.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
A critical appraisal of clinical practice guidelines for the treatment of lower-limb osteoarthritis

Clinical practice guidelines are important tools to assist clinical decision-making. Recently, several guidelines addressing the management of osteoarthritis (OA) have been published. Clinicians treating patients with OA must ensure that these guidelines are developed with consistency and methodological rigour. We undertook a qualitative summary and critical appraisal of six medical treatment guidelines for the management of lower-limb OA published in the medical literature within the past 5 years. A review of these six guidelines revealed that each possesses strengths and weakness. While most described the scope and intended patient populations, the guidelines varied considerably in the rigour of their development, coverage of implementation issues, and disclosure of conflicts of interest.

Tags: clinical-guidelines, lower-limb-oa, nih, osteoarthritis, osteoarthritis-treatment
Organization: U.S. Department of Health & Human Services
Oxygen and nitrate-dependent regulation of

Background
          Escherichia coli can respire anaerobically using dimethyl sulfoxide (DMSO) or trimethylamine-N-oxide (TMAO) as the terminal electron acceptor for anaerobic energy generation. Expression of the dmsABC genes that encode the membrane-associated DMSO/TMAO reductase is positively regulated during anaerobic conditions by the Fnr protein and negatively regulated by the NarL protein when nitrate is present.
        
        
          Results
          The regions of dmsA regulatory DNA required for Fnr and NarL interactions in response to anaerobiosis and nitrate, respectively, were examined. Mutations within the Fnr site that deviated from the wild type sequence, TTGATaccgAACAA, or that removed an entire half-site, either impaired or abolished the anaerobic activation of dmsA-lacZ expression. The region for phosphorylated NarL (NarL-phosphate) binding at the dmsA promoter was identified by DNase I and hydroxyl radical footprinting methods. A large 97 bp region that overlaps the Fnr and RNA polymerase recognition sites was protected by NarL-phosphate but not by the non-phosphorylated form of NarL. Hydroxyl radical footprinting analysis confirmed the NarL-phosphate DNase I protections of both dmsA strands and revealed 8–9 protected sites of 3–5 bp occurring at ten bp intervals that are offset by 3 bp in the 3' direction.
        
        
          Conclusion
          These findings suggest that multiple molecules of phosphorylated NarL bind along one face of the DNA and may interfere with Fnr and/or RNA polymerase interactions at the dmsA regulatory region. The interplay of these transcription factors insures a hierarchical expression of the dmsABC genes when respiration of the preferred electron acceptors, oxygen and nitrate, is not possible.

Tags: anaerobic-respiration, escherichia-coli, gene-regulation, nih
Organization: U.S. Department of Health & Human Services
Annual Report to Congress on State Child Welfare Expenditures Reported on the CFS-101 (2024)

This report to Congress provides national totals of planned spending by service category for the Stephanie Tubbs Jones Child Welfare Services program and planned and actual spending by service category for the Promoting Safe and Stable Families program.

For questions on or to obtain Attachment B, please contact Linda Viales for assistance.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, policy, reporting, scope, social
Organization: U.S. Department of Health & Human Services
Compound 527567: 1,4-Cyclohexadiene, 6-iodo-1-methyl

Chemical compound data from PubChem database. IUPAC Name: 6-iodo-1-methylcyclohexa-1,4-diene. Molecular Formula: C7H9I. Molecular Weight: 220.05. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528830: 17alpha(H),21beta(H)-(22R)-TETRAKISHOMOHOPANE

Chemical compound data from PubChem database. IUPAC Name: 3-heptan-2-yl-5a,5b,8,8,11a,13b-hexamethyl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysene. Molecular Formula: C34H60. Molecular Weight: 468.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527893: 7-Chlorodecyl acetate

Chemical compound data from PubChem database. IUPAC Name: 7-chlorodecyl acetate. Molecular Formula: C12H23ClO2. Molecular Weight: 234.76. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
The Impact of Development Methodologies, Software Frameworks, and Platform Choices on Release Management

Through the webinar series, "Back to Basics," the Division of State Systems within the Children's Bureau is offering a venue for information sharing and discussion. The fifth webinar of the series, “The Impact of Development Methodologies, Software Frameworks and Platform Choices on Release Management,” reviews the ways in which these different elements impact software release.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: metadata, policy, scope, system, webinar
Organization: U.S. Department of Health & Human Services
Compound 528586: tert-Butyl(dimethyl)silyl nonanoate

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] nonanoate. Molecular Formula: C15H32O2Si. Molecular Weight: 272.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin

Background
          We investigated the chemopreventive action of dietary curcumin on 7,12-dimethylbenz(a)anthracene (DMBA)-initiated and 12,0-tetradecanoylphorbol-13-acetate (TPA)-promoted skin tumor formation in Swiss albino mice. Curcumin, a yellow coloring matter isolated from roots of Curcuma longa Linn, is a phenolic compound possessing antioxidant, free radical scavenger, and antiinflammatory properties. It has been shown by previously reported work that TPA-induced skin tumors were inhibited by topical application of curcumin, and curcumin has been shown to inhibit a variety of biological activities of TPA. Topical application of curcumin was reported to inhibit TPA-induced c-fos, c-jun and c-myc gene expression in mouse skin. This paper reports the effects of orally administered curcumin, which was consumed as a dietary component at concentrations of 0.2 % or 1 %, in ad libitum feeding.
        
        
          Results
          Animals in which tumors had been initiated with DMBA and promoted with TPA experienced significantly fewer tumors and less tumor volume if they ingested either 0.2% or 1% curcumin diets. Also, the dietary consumption of curcumin resulted in a significantly decreased expression of ras and fos proto-oncogenes in the tumorous skin, as measured by enhanced chemiluminesence Western blotting detection system (Amersham).
        
        
          Conclusions
          Whereas earlier work demonstrated that topical application of curcumin to mouse skin inhibited TPA-induced expression of c-fos, c-jun and c-myc oncogenes, our results are the first to show that orally consumed curcumin significantly inhibited DMBA- and TPA-induced ras and fos gene expression in mouse skin.

Tags: curcumin-chemoprevention, dmba-induced-tumors, nih, oncogene-expression, skin-cancer
Organization: U.S. Department of Health & Human Services
Compound 526826: 12-Hydroxy-heptadecanoic acid, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 12-[tert-butyl(dimethyl)silyl]oxyheptadecanoate. Molecular Formula: C24H50O3Si. Molecular Weight: 414.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525375: Butane, 2-[(1-methylethyl)thio]-

Chemical compound data from PubChem database. IUPAC Name: 2-propan-2-ylsulfanylbutane. Molecular Formula: C7H16S. Molecular Weight: 132.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Texas

This is the 2021 Uniform Reporting System (URS) Output Tables for Texas. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, outcome-measures, samhsa, texas
Organization: U.S. Department of Health & Human Services
Patent AT-E400440-T1: [Translated] IMAGE FORMING DEVICE HAVING A MULTIPLE SHEET CASSETTES, IMAGE FORMING SYSTEM AND PROGRAM PRODUCT

An image forming apparatus including: an image forming unit; plural trays; a sheet feed unit that feeds a sheet held in one of the trays; a correspondence storing unit that stores correspondence between trays and kinds of sheets; a priority setting unit that sets priority to a designation of the tray or to a designation of the kind; a sheet feed control unit that feeds the sheet from one of the trays when the priority is given to the designation of the tray and the one of the trays is designated, and searches one of the trays that holds the sheet of the designated kind based on the correspondence to feed the sheet from the searched tray when the priority is given to the designation of the kind and the kind of the sheet is designated; and a setting change unit that changes a setting of the image forming unit correspondingly to the kind of sheet.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Patent AT-E400747-T1: [Translated] METHOD FOR PRODUCING A CONE RING WITH A SINNER FRICTION LINING

Method involves producing conical base ring having truncated torus, coating stainless steel support with scatter-sinter layer, which are baked to give sintered friction lining. Sintered friction lining is separated from stainless steel support after baking. Unwound sintered friction lining so obtained is inserted in base and unwound sintered friction lining is fastened on torus of base ring by material fit. An independent claim is also included for the cone ring.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 528552: 7-Methylnonadecane

Chemical compound data from PubChem database. IUPAC Name: 7-methylnonadecane. Molecular Formula: C20H42. Molecular Weight: 282.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E399674-T1: [Translated] DEVICE FOR DETECTING THE PRESENCE OF AN OCCUPANT

The purpose of this invention is to sense the presence of a seated occupant in a vehicle such as an automobile, plane, train or bus, or in a room or location where it is desirable to detect if seats are occupied. The occupant presence detection device consists of a single seat-mounted electrode, an oscillator circuit, a bridge circuit, a detection circuit and a circuit for processing the detected signals. The oscillator circuit excites the electrode. If an occupant is present on the seat, additional capacitance from the human body is introduced into the bridge via the electrode. This created differences in the voltage and phase of the waveform in each arm of the bridge circuit which are amplified by a differential amplifier. The signal is then converted to a DC voltage that, when above a predetermined threshold, causes the device to outputs a signal that indicates the presence of an occupant. Using a bridge configuration and a differential amplifier allows the circuit to be operated over a wide range of supply voltages. It also reduces the need for high precision components and the need to regulate the amplitude of the waveform produced by the oscillator. The net result is a capacitive occupant sensing device that is less complex and less expensive that previous capacitive occupant sensing devices, yet is tolerant of power supply fluctuations, is able to function over a wide range of operating voltage and still provides failsafe functionality.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Table 7. Cocaine Use in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 7. Cocaine Use in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Tags: cocaine-use, drug-prevalence, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Patent AT-E400466-T1: [Translated] VEHICLE SEAT

A vehicle seat (30) is movable rearwardly with a pivoting action in response to forces applied to the seat in a rear impact. The seat is provided with an energy absorbing unit (1). A clamp (20, 21, 22, 23) is provided which can engage a deformable strip (8) that forms part of the energy absorbing unit (1) when a relatively high impact force is applied, indicative of a rear impact. The clamping action prevents any subsequent rearward movement of the vehicle seat (1).

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Use of neuroleptics in a general hospital

Background
          This study investigates the clinical use of neuroleptics within a general hospital in acutely ill medical or surgical patients and its relation with dementia three months after admission compared with control subjects.
        
        
          Methods
          Cases were defined as every adult patient to whom a neuroleptic medication was prescribed during their hospitalization in our Hospital from February 1st, to June 30th, 1998. A control matched by age and sex was randomly selected among patients who had been admitted in the same period, in the same department, and had not received neuroleptics drugs (205 cases and 200 controls). Demographic, clinical and complementary data were compared between cases and controls. Crude odds ratios estimating the risk of dementia in non previously demented subjects compared with the risk in non-demented control subjects were calculated.
        
        
          Results
          205 of 2665 patients (7.7%) received a neuroleptic drug. The mean age was 80.0 ± 13.6 years and 52% were females. They were older and stayed longer than the rest of the population. Only 11% received a psychological evaluation before the prescription. Fifty two percent were agitated while 40% had no reason justifying the use of neuroleptic drug. Three months after neuroleptic use 27% of the surviving cases and 2.6% of the surviving controls who were judged non-demented at admission were identified as demented.
        
        
          Conclusions
          The most common reason for neuroleptic treatment was to manage agitation symptomatically in hospitalised patients. Organic mental syndromes were rarely investigated, and mental status exams were generally absent. Most of neuroleptic recipients had either recognised or unrecognised dementia.

Tags: antipsychotic-medication, dementia-risk, hospital-patients, neuroleptic-use, nih
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for Puerto Rico

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Puerto Rico. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, outcome-measures, puerto-rico, samhsa
Organization: U.S. Department of Health & Human Services
Adults in Poor Physical Health Reporting Behavioral Health Conditions Have Higher Health Costs

This report uses 2012 Medical Expenditure Panel Survey (MEPS) data.  Adults aged 18 to 64 in poor physical health who also reported behavioral health conditions (i.e., mental health or substance use disorders) had higher total health care expenditures than adults in poor health without behavioral health conditions. These higher total health care expenditures were caused by higher physical health care expenditures. These higher total health care expenditures hold for all types of health insurance coverage.

Tags: behavioral-health, healthcare-expenditures, meps-data, physical-health, samhsa
Organization: U.S. Department of Health & Human Services
Patent AT-E400485-T1: [Translated] SLIDING TARP SYSTEM FOR COVERING, ESPECIALLY FOR A FREIGHT WAGON SUCH AS A RAILWAY WAGON

The system, comprising a series of tarpaulin supporting arches (3) that slide along lengthwise rails (4), and intermediate arches (6) between them pivoted to the main arches, has flexible strips (7) connecting the intermediate arches on adjacent pairs of main arches. The strips occupy a contracted position when the intermediate arches are folded, and an extended position when the intermediate arches are deployed and the main arches are in position to support. Each flexible strip has a curved middle section and two rolled ends to fit round the intermediate arches, and is made from an elastically deformable metal such as stainless steel with a plastic coating.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 526205: 4-sec-Butyl-2-tert-butyl-6-hydroperoxymethyl-phenol

Chemical compound data from PubChem database. IUPAC Name: 4-butan-2-yl-2-tert-butyl-6-(hydroperoxymethyl)phenol. Molecular Formula: C15H24O3. Molecular Weight: 252.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Rheumatoid arthritis viewed using a headache paradigm

Results and new hypotheses in animal models often stimulate			 development of new paradigms in how we view rheumatoid arthritis (RA). The			 complexity of RA does, however, eventually lead to the rejection of these			 hypotheses. Here, it is argued that the large number of so-far described animal			 models, when taken together, also reveals a complex disease. Fortunately,			 detailed study of each of the animal models will reveal this complexity, and			 may also be helpful in elucidating the complexity of the human disease. Benoist			 and Mathis [1] recently contributed a new animal model in			 which an autoimmune response to a ubiquitous antigen leads to an			 antibody-mediated inflammatory attack in the joints. It is argued that this new			 model, as with other animal models, is unlikely to explain RA, but it will add			 to the tools available to reveal the complexity of RA.

Tags: animal-models, autoimmune-disease, joint-inflammation, nih, rheumatoid-arthritis
Organization: U.S. Department of Health & Human Services
4.15a Facility licensing, certification, or accreditation, by facility operation and primary focus of facility: 2011. Number

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing facility licensing, certification, or accreditation, by facility operation and primary focus of facility in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: accreditation-status, facility-licensing, n-ssats, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
Compound 526113: 2,12-Dimethylheptacosane

Chemical compound data from PubChem database. IUPAC Name: 2,12-dimethylheptacosane. Molecular Formula: C29H60. Molecular Weight: 408.8. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services