AndreaBozzo/ceres-open-data-index huggingface dataset:
Comparison of 2002-2003 and 2012-2013 NSDUH State Prevalence Estimates

A comparsison of  2002-2003 and 2012-2013 state estimates is shown for individuals aged 12 or older, 12 to 17, 18 to 25, and 26 or older; also for individuals aged 12 to 20 for two alcohol measures.

Tags: alcohol-consumption, nsduh, samhsa, state-prevalence, substance-use
Organization: U.S. Department of Health & Human Services
Model-supported estimation of mortality rates in Baltic cod (

Background
          Changes in the survival-rate during the larval phase may strongly influence the recruitment level in marine fish species. During the larval phase different 'critical periods' are discussed, e.g. the hatching period and the first-feeding period. No such information was available for the Baltic cod stock, a commercially important stock showing reproduction failure during the last years. We calculated field-based mortality rates for larval Baltic cod during these phases using basin-wide abundance estimates from two consecutive surveys. Survey information was corrected by three dimensional hydrodynamic model runs.
        
        
          Results
          The corrections applied for transport were of variable impact, depending on the prevailing circulation patterns. Especially at high wind forcing scenarios, abundance estimates have the potential to be biased without accounting for transport processes. In May 1988 mortality between hatch and first feeding amounted to approximately 20% per day. Mortality rates during the onset of feeding were considerably lower with only 7% per day. In August 1991 the situation was vice versa: Extremely low mortality rates of 0.08% per day were calculated between hatch and first feeding, while the period between the onset of feeding to the state of an established feeder was more critical with mortality rates of 22% per day.
        
        
          Conclusions
          Mortality rates during the different proposed 'critical periods' were found to be highly variable. Survival rates of Baltic cod are not only influenced by a single 'critical period', but can be limited at different points during the larval phase, depending on several biotic and abiotic factors.

Tags: baltic-cod, fish-population, larval-survival, mortality-rates, nih
Organization: U.S. Department of Health & Human Services
Summary of the Title IV-E Child Welfare Waiver Demonstrations (July 2018)

This document provides an overview of the Child Welfare Waiver Demonstration projects active as of Federal Fiscal Year 2018, including programmatic goals, proposed service interventions, and evaluation designs for individual projects.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, data, fiscal, intervention, policy
Organization: U.S. Department of Health & Human Services
Alaska 2016 Potential Areas for Addressing Service Gaps for Opioid Treatment

The purpose of the medication-assisted treatment (MAT) facility maps is to identify areas on a state-by-state basis that may be potentially underserved by existing treatment facilities. The maps are created with a methodology that seeks to include the highest potential need areas from individual counties so that county-level stakeholders are also informed. The maps are meant to be used as a tool for policy makers to determine potentially underserved areas—not as a definitive representation of these areas.

Tags: alaska-opioids, mat-access, opioid-treatment, samhsa, service-gap-analysis
Organization: U.S. Department of Health & Human Services
Table of the Title IV-E Child Welfare Waiver Demonstrations Active between 2012 to 2019 (March 2021)

This document provides a summary table of the Child Welfare Waiver Demonstration projects active between 2012 to 2019.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, data, policy, project, social
Organization: U.S. Department of Health & Human Services
Compound 525369: 2,4,4-Trimethyl-3-thiahexane

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-propan-2-ylsulfanylbutane. Molecular Formula: C8H18S. Molecular Weight: 146.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
National Substance Use And Mental Health Services Survey (N-SUMHSS): 2022 Data On Substance Use And Mental Health Treatment Facilities

This report presents results from the 2022 National Substance Use and Mental Health Services Survey (N-SUMHSS), an annual survey of substance use and mental health treatment facilities in the United States. Conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), the N-SUMHSS is designed to collect data on the location, characteristics, service provision and utilization of substance use and mental health treatment facilities.

Tags: behavioral-health, mental-health-services, samhsa, substance-use-treatment, treatment-facility-survey
Organization: U.S. Department of Health & Human Services
2011 State Profile — Wyoming

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing state profile for Wyoming in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: n-ssats, samhsa, substance-abuse-treatment, treatment-facilities, wyoming
Organization: U.S. Department of Health & Human Services
Comparing and Evaluating Substance Use Treatment Utilization Estimates from the National Survey on Drug Use and Health and Other Data Sources

This report presents an evaluation of the coverage, overlap, biases, strengths, and weaknesses of three sources of data on the receipt of specialty substance use treatment: the National Survey on Drug Use and Health (NSDUH), the National Survey of Substance Abuse Treatment Services (N-SSATS), and the Treatment Episode Data Set (TEDS). Specialty substance use treatment measures compared include numbers and characteristics of persons treated in a given year, single-day treatment counts, numbers of admissions in a given year, and estimates of the numbers of persons who needed substance use treatment but did not receive it. This report includes data from the 2005 through 2010 NSDUHs; 2007 through 2009 N-SSATS; and 2007 through 2009 TEDS. Results are show by substance treated, age, race/ethnicity, and employment status,

Tags: nsduh-nssats-teds, samhsa, substance-abuse, substance-use-treatment, treatment-utilization
Organization: U.S. Department of Health & Human Services
Past Year Major Depressive Episodes More Common Among Adolescents With Asthma

This spotlight uses 2013 to 2014 National Surveys on Drug Use and Health (NSDUH) data to examine the association between asthma and depression among adolescents aged 12 to 17 by age group.

Tags: adolescent-depression, asthma-comorbidity, mental-health, nsduh-data, samhsa
Organization: U.S. Department of Health & Human Services
New Jersey (NJ)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for New Jersey for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: major-depressive-episode, mental-health, samhsa, serious-mental-illness, substance-use
Organization: U.S. Department of Health & Human Services
Variability within individuals of plasma ionic magnesium concentrations

Background
          With the invention of the ion-selective electrode (ISE), ionic magnesium (iMg) is a common blood assay. This could be advantageous, as iMg is the biologically active form of Mg. There is some evidence that iMg has considerable within subject variability.
        
        
          Results
          Individual ranges averaged .08 mmol/L (range .05 to .14). Coefficients of variation (CV) ranged from 3% to 7% (mean 4%) while analytical variation was determined to be 2.3%. Biological variability thus accounts for almost half of the variability, which is clinically significant, as 9 of the 13 subjects recorded at least one value below a reference range of .46 – .60 mmol/L. A significant within-day variation (p < .001) was noted, with differences between 7:00 and 10:00 as well as 10:00 and 22:00. Between day variations were not significant (p = .56).
        
        
          Conclusions
          A plausible explanation of this data is that iMg has a circadian rhythm. Thus, cautious interpretation of single iMg values is warranted until future research determines the nature of iMg variability.

Tags: biological-variation, circadian-rhythm, ionic-magnesium, magnesium-levels, nih
Organization: U.S. Department of Health & Human Services
Reliability, Validity and Psychometric Properties of the Greek Translation of the Center for Epidemiological Studies-Depression (CES-D) Scale

Introduction
          The aim of the current study was to assess the reliability, validity and psychometric properties of the Greek translation of the Center for Epidemiological Studies- Depression Scale (CES-D).
        
        
          Methods
          40 depressed patients 29.65 ± 9.38 years old, and 120 normal controls 27.23 ± 10.62 years old entered the study. In 20 of them (12 patients and 8 controls) the instrument was re-applied 1-2 days later. Translation and Back Translation was made. Clinical Diagnosis was reached by consensus of two examiners with the use of the SCAN v.2.0 and the IPDE. Statistical Analysis included ANOVA, the Pearson Product Moment Correlation Coefficient, Principal Components Analysis and Discriminant Function Analysis and the calculation of Cronbach's alpha (α)
        
        
          Results
          Both Sensitivity and specificity exceed 90.00 at 23/24, Chronbach's alpha for the total scale was equal to 0.95. Factor analysis revealed three factors (positive affect, irritability and interpersonal relationships, depressed affect and somatic complains). The test-retest reliability was satisfactory (Pearson's R between 0.45 and 0.95 for individual items and 0.71 for total score).
        
        
          Conclusion
          The Greek translation of the CES-D scale is both reliable and valid and is suitable for clinical and research use with satisfactory properties. Its properties are similar to those reported in the international literature. However one should always have in mind the limitations inherent in the use of self-report scales.

Tags: ces-d-scale, depression-screening, mental-health, nih, psychometric-properties
Organization: U.S. Department of Health & Human Services
Compound 528431: 1-Tetradecene, 8-butyl

Chemical compound data from PubChem database. IUPAC Name: 8-butyltetradec-1-ene. Molecular Formula: C18H36. Molecular Weight: 252.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
A quantitative PCR (TaqMan) assay for pathogenic

Background
          Leptospirosis is an emerging infectious disease. The differential diagnosis of leptospirosis is difficult due to the varied and often "flu like" symptoms which may result in a missed or delayed diagnosis. There are over 230 known serovars in the genus Leptospira. Confirmatory serological diagnosis of leptospirosis is usually made using the microscopic agglutination test (MAT) which relies on the use of live cultures as the source of antigen, often performed using a panel of antigens representative of local serovars. Other techniques, such as the enzyme linked immunosorbent assay (ELISA) and slide agglutination test (SAT), can detect different classes of antibody but may be subject to false positive reactions and require confirmation of these results by the MAT.
        
        
          Methods
          The polymerase chain reaction (PCR) has been used to detect a large number of microorganisms, including those of clinical significance. The sensitivity of PCR often precludes the need for isolation and culture, thus making it ideal for the rapid detection of organisms involved in acute infections. We employed real-time (quantitative) PCR using TaqMan chemistry to detect leptospires in clinical and environmental samples.
        
        
          Results and Conclusions
          The PCR assay can be applied to either blood or urine samples and does not rely on the isolation and culture of the organism. Capability exists for automation and high throughput testing in a clinical laboratory. It is specific for Leptospira and may discriminate pathogenic and non-pathogenic species. The limit of detection is as low as two cells.

Tags: infectious-disease, leptospirosis-diagnosis, nih, qpcr-assay, taqman-pcr
Organization: U.S. Department of Health & Human Services
NSDUH 2021 Statistical Inference Report

Learn how to produce basic estimates with the 2021 National Survey on Drug Use and Health (NSDUH). The report describes the techniques that were used to make the 2021 NSDUH Detailed Tables and the 2021 NSDUH Annual National Report, but users may also find these techniques useful for their own research with NSDUH. The report describes the calculation of estimates and sampling errors, degrees of freedom, and the procedures for determining when low-precision estimates should be suppressed. It also includes sample code in several statistical languages that data users can modify to use in their own research.Chapters:Introduction to the report.Background on the survey design, including redesign and questionnaire changes.Prevalence estimates and how they were calculated, including specifics on various topics presented in the detailed tables.Discussion of how missing item responses of variables that are not imputed may lead to biased estimates.Discussion of sampling errors and how they were calculated.Description of degrees of freedom and how they were used to compare estimates.Discussion of how the statistical significance of differences between estimates was determined.Discussion of confidence interval estimation.Discussion of when estimates with low precision were suppressed.Appendix A contains code samples for various statistical procedures documented within the report.

Tags: mental-health, samhsa, statistical-analysis, substance-use, survey-methodology
Organization: U.S. Department of Health & Human Services
Mobilization of seed storage lipid by Arabidopsis seedlings is retarded in the presence of exogenous sugars

Background
          Soluble sugar levels must be closely regulated in germinating seeds to ensure an adequate supply of energy and building materials for the developing seedling. Studies on germinating cereal seeds indicate that production of sugars from starch is inhibited by increasing sugar levels. Although numerous studies have focused on the regulation of starch metabolism, very few studies have addressed the control of storage lipid metabolism by germinating oilseeds.
        
        
          Results
          Mobilization of storage lipid by germinating seeds of the model oilseed plant Arabidopsis thaliana (L.) Heynh. occurs at a greatly reduced rate in the presence of exogenous glucose or mannose, but not in the presence of equi-molar 3-O-methylglucose or sorbitol. The sugar-insensitive5-1/abscisic acid-insensitive4-101 (sis5-1/abi4-101) mutant is resistant to glucose inhibition of seed storage lipid mobilization. Wild-type seedlings become insensitive to glucose inhibition of storage lipid breakdown within 3 days of the start of imbibition.
        
        
          Conclusions
          Growth in the presence of exogenous glucose significantly retards mobilization of seed storage lipid in germinating seeds from wild-type Arabidopsis. This effect is not solely due to the osmotic potential of the media, as substantially higher concentrations of sorbitol than of glucose are required to exert significant effects on lipid breakdown. The inhibitory effect of glucose on lipid breakdown is limited to a narrow developmental window, suggesting that completion of some critical metabolic transition results in loss of sensitivity to the inhibitory effect of glucose on lipid breakdown.

Tags: arabidopsis-thaliana, glucose-inhibition, lipid-metabolism, nih, seed-germination
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for North Dakota

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for North Dakota.  The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, mental-health-services, north-dakota, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 525425: 2-Thienylethylthiomethane

Chemical compound data from PubChem database. IUPAC Name: 2-(ethylsulfanylmethyl)thiophene. Molecular Formula: C7H10S2. Molecular Weight: 158.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: HHS Region III, 2014

This is a behavioral health report for HHS Region III of the United States and utilizes data from the National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment (N-SSATS), collected annually. The topics addressed in the reports include youth substance use, adult mental health and treatment, and substance use treatment.

Tags: behavioral-health, hhs-region-iii, mental-health, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Compound 525626: N,N-Dimethyl-N'-heptyl-benzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-heptyl-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C16H26N2. Molecular Weight: 246.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525273: N,N-Dimethyl-N'-(3-nitrophenyl)ethanimidamide

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-(3-nitrophenyl)ethanimidamide. Molecular Formula: C10H13N3O2. Molecular Weight: 207.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for Iowa

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Iowa. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, iowa, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Key Substance Use and Mental Health Indicators in the United States: Results from the 2016 National Survey on Drug Use and Health

This national report summarizes key findings from the 2016 National Survey on Drug Use and Health (NSDUH) for indicators of substance use and mental health among people aged 12 years old or older in the civilian, noninstitutionalized population of the United States.  Estimates include tobacco use, alcohol use, illicit drug use, opioid use, substance use disorders, major depressive episode, any mental illness, serious mental illness, suicide, co-occurring disorders, and receipt of treatment or services.

Tags: co-occurring-disorders, mental-health, nsduh-survey, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology

Background
          An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to considerable concern about the safety of the vaccine.
        
        
          Methods
          A matched case-control study using data derived form the United Kingdom General Practice Research Database. Children with a possible diagnosis of autism will be identified from their electronic health records. All diagnoses will be validated by a detailed review of hospital letters and by using information derived from a parental questionnaire. Ten controls per case will be selected from the database. Conditional logistic regression will be used to assess the association between MMR vaccination and autism. In addition case series analyses will be undertaken to estimate the relative incidence of onset of autism in defined time intervals after vaccination. The study is funded by the United Kingdom Medical Research Council.
        
        
          Discussion
          Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results.

Tags: autism-spectrum-disorder, case-control-study, mmr-vaccination, nih, vaccine-safety
Organization: U.S. Department of Health & Human Services
2012 Uniform Reporting System (URS) Tables for Iowa

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, iowa-mental-health, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services