AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 525075: Naphthalene, 2-(1-methylpropyl)

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-ylnaphthalene. Molecular Formula: C14H16. Molecular Weight: 184.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E401273-T1: [Translated] GRIPPER DEVICE

The device (1) comprises multiple grippers (5) arranged together in a position with a pre-determined distance. A rocker comprises a swiveling point at the frame (4), where a drive unit (7) has a translational movement (10) for moving two adjacent grippers over different lengths. The coupling elements are connected with the rocker of other gripper by one swiveling point.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Cellophane based mini-prep method for DNA extraction from the filamentous fungus

Background
          Methods for the extraction of DNA from filamentous fungi are frequently laborious and time consuming because most of the available protocols include maceration in liquid nitrogen after the mycelium has been grown in a liquid culture. This paper describes a new method to replace those steps, which involves the growth of the mycelium on cellophane disks overlaid on solid medium and the use of glass beads for cell wall disruption.
        
        
          Results
          Extractions carried out by this method provided approximately 2 μg of total DNA per cellophane disk for the filamentous fungus Trichoderma reesei. To assess the DNA's quality, we made a PCR (Polymerase Chain Reaction) amplification of a gene introduced by a transformation in this fungus's genome (hph gene), with successful results. We also confirmed the quality of the DNA by the use of Southern blotting to analyze the presence of the same gene, which was easily detected, resulting in a sharply defined and strong band.
        
        
          Conclusions
          The use of this method enabled us to obtain pure DNA from Trichoderma reesei, dispensing with the laborious and time-consuming steps involved in most protocols. The DNA obtained was found to be suitable for PCR and Southern blot analyses. Another advantage of this method is the fact that several samples can be processed simultaneously, growing the fungus on multiple well cell culture plates. In addition, the absence of maceration also reduces sample handling, minimizing the risks of contamination, a particularly important factor in work involving PCR.

Tags: dna-extraction, filamentous-fungi, molecular-method, nih, trichoderma-reesei
Organization: U.S. Department of Health & Human Services
Table 11. 2011-2012 NSDUH Perceptions of Great Risk of Having Five or More Drinks of an Alcoholic Beverage Once or Twice a Week, by Age Group and State

Table 11. Perceptions of Great Risk of Having Five or More Drinks of an Alcoholic Beverage Once or Twice a Week, by Age Group and State. Results are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: adolescent-alcohol-use, alcohol-risk-perception, binge-drinking, nsduh-data, samhsa
Organization: U.S. Department of Health & Human Services
Compound 525693: p-Methoxybenzylidene-(3-bromophenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: N-(3-bromophenyl)-1-(4-methoxyphenyl)methanimine. Molecular Formula: C14H12BrNO. Molecular Weight: 290.15. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525775: 2,4-Dimethyl-5-butyloxazole

Chemical compound data from PubChem database. IUPAC Name: 5-butyl-2,4-dimethyl-1,3-oxazole. Molecular Formula: C9H15NO. Molecular Weight: 153.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Kentucky

This is the 2020 Uniform Reporting System (URS) Output Tables for Kentucky. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, kentucky-urs, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 526811: 15-Hydroxy-heptadecanoic acid, methyl ester, tBDMS ether

Chemical compound data from PubChem database. IUPAC Name: methyl 15-[tert-butyl(dimethyl)silyl]oxyheptadecanoate. Molecular Formula: C24H50O3Si. Molecular Weight: 414.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2017 Uniform Reporting System (URS) Table for Maryland

This is the 2017 Uniform Reporting System (URS) Output Tables for Maryland. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, maryland, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
2019 Uniform Reporting System (URS) Table for Colorado

These are the 2019 Uniform Reporting System (URS) Output Tables for Colorado. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Serine / threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling

Background
          In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated GR-complex regulates the transcription of GR-responsive genes. Serine/threonine protein phosphatase type 5 (PP5) associates with the GR-heat-shock protein-90 complex, and the suppression of PP5 expression with ISIS 15534 stimulates the activity of GR-responsive reporter plasmids, without affecting the binding of hormone to the GR.
        
        
          Results
          To further characterize the mechanism by which PP5 affects GR-induced gene expression, we employed immunofluorescence microscopy to track the movement of a GR-green fluorescent fusion protein (GR-GFP) that retained hormone binding, nuclear translocation activity and specific DNA binding activity, but is incapable of transactivation. In the absence of glucocorticoids, GR-GFP localized mainly in the cytoplasm. Treatment with dexamethasone results in the efficient translocation of GR-GFPs into the nucleus. The nuclear accumulation of GR-GFP, without the addition of glucocorticoids, was also observed when the expression of PP5 was suppressed by treatment with ISIS 15534. In contrast, ISIS 15534 treatment had no apparent effect on calcium induced nuclear translocation of NFAT-GFP.
        
        
          Conclusion
          These studies suggest that PP5 participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling, and that the GR-induced transcriptional activity observed when the expression of PP5 is suppressed by treatment with ISIS 15534 results from the nuclear accumulation of GR in a form that is capable of binding DNA yet still requires agonist to elicit maximal transcriptional activation.

Tags: gene-expression-regulation, glucocorticoid-receptor, nih, nucleocytoplasmic-shuttling, protein-phosphatase-5
Organization: U.S. Department of Health & Human Services
Diuretics: again the first step in the treatment of most patients with hypertension

The results and interpretations of the most recent controlled clinical trials on antihypertensive drugs have fuelled the debate about the drug that should be used to begin treatment for hypertension. Every comparison of diuretics with other drugs has shown that the benefits of diuretics are equivalent to, or better than, other options. These findings, together with other practical reasons, such as left ventricular mass reducing effect, easy administration, few side effects and low cost, suggest that diuretics should regain their primacy as the first step in drug management of hypertension.

Tags: antihypertensive-drugs, clinical-trials, diuretic-therapy, hypertension-treatment, nih
Organization: U.S. Department of Health & Human Services
2023 Uniform Reporting System (URS) Table For Michigan

This is the 2023 Uniform Reporting System (URS) Output Tables for Michigan. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: mental-health-services, michigan-mental-health, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Compound 529376: Val, N-isoBOC TBDMS

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 3-methyl-2-(2-methylpropoxycarbonylamino)butanoate. Molecular Formula: C16H33NO4Si. Molecular Weight: 331.52. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400554-T1: [Translated] 2-ARYLETHYL-(PIPERIDINE-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARIINE RECEPTOR ANTAGONISTS

Chemical patent from PubChem database. Patent Number: AT-E400554-T1. Title: Method for Synthesizing Organic Compounds. Filing Date: 1992-11-14. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: A method for synthesizing organic compounds is disclosed, comprising reacting starting materials under specific conditions to yield the desired produc... IPC Classifications: A61K, A61P, C07D. This patent covers 29 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 530125: Nonane, 5-ethyl-4-propyl

Chemical compound data from PubChem database. IUPAC Name: 5-ethyl-4-propylnonane. Molecular Formula: C14H30. Molecular Weight: 198.39. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525881: N,N-Dimethyl-N'-(3-nitrophenyl)-pivalamidine

Chemical compound data from PubChem database. IUPAC Name: N,N,2,2-tetramethyl-N'-(3-nitrophenyl)propanimidamide. Molecular Formula: C13H19N3O2. Molecular Weight: 249.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526479: N-[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-trimethylsilyloxypropyl]-2,2,3,3,4,4,4-heptafluoro-N-propan-2-ylbutanamide

Chemical compound data from PubChem database. IUPAC Name: N-[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-trimethylsilyloxypropyl]-2,2,3,3,4,4,4-heptafluoro-N-propan-2-ylbutanamide. Molecular Formula: C25H36F7NO4Si. Molecular Weight: 575.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400065-T1: [Translated] DEVICE FOR RESISTIVE CURRENT LIMITATION WITH A TAPE-SHAPED HIGH-TC SUPERCONDUCTOR TRACK

The resistive current-limiting device contains a strip-shaped superconductor having a conductive structure which is made of a metallic substrate strip, an insulating, oxidic buffer layer, a super-conductive layer made of a type AB2Cu3Ox oxidically high-Tc-super conductive material, an insulating buffer layer which is arranged therebetween, and a metal cover layer. At least one of the lateral edges of the conductive structure is mechanically deformed such that the cover layer and the substrate strip are arranged in electric contact.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 527842: 2,4-Dichlorobenzyl dodecyl ether

Chemical compound data from PubChem database. IUPAC Name: 2,4-dichloro-1-(dodecoxymethyl)benzene. Molecular Formula: C19H30Cl2O. Molecular Weight: 345.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Child and Caregiver Outcomes Using Linked Data (CCOULD)

The Child and Caregiver Outcomes Using Linked Data (CCOULD) project developed consistent state datasets containing linked child and caregiver welfare records and Medicaid claims and enrollment records. These datasets contain information from both child welfare and Medicaid information systems on case demographics, medical diagnoses, services, outcomes, and other relevant information. The purpose of the data is to support research on the relationships between Medicaid utilization, behavioral health services, patient-centered outcomes, and child welfare outcomes. Of particular interest are outcomes for families that may have substance use disorders, like opioid use disorder.


The CCOULD project worked with Kentucky and Florida (specifically the Florida Department of Children and Families, the Florida Agency for Health Care Administration, and the Kentucky Cabinet for Health and Family Services) to produce linked, state-level data to support research on the relationships among Medicaid utilization, behavioral health services, patient-centered outcomes, and child welfare outcomes. State-level linked data were combined into a de-identified, standardized research use dataset containing data from the two participating states.


Documentation for the data includes:

Investigators: Tami L. Mark, PhD, RTI International
Melissa Dolan, PhD, RTI International
Benjamin Allaire, MS, RTI International
Keith Smith, BS, RTI International
William Parish, PhD, RTI International
Christina Bradley, MA, RTI International
Claire Strack, BS, RTI International

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
Compound 529075: 1H-Pyrrole, 1-methyl-2-propyl

Chemical compound data from PubChem database. IUPAC Name: 1-methyl-2-propylpyrrole. Molecular Formula: C8H13N. Molecular Weight: 123.2. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528023: 2-Phenylethyl 4-nitrobenzoate

Chemical compound data from PubChem database. IUPAC Name: 2-phenylethyl 4-nitrobenzoate. Molecular Formula: C15H13NO4. Molecular Weight: 271.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525333: 1-(5',6'-dihydroxyhexyl)-3,7-dimethylxanthine, O-TFA

Chemical compound data from PubChem database. IUPAC Name: [6-(3,7-dimethyl-2,6-dioxopurin-1-yl)-2-(2,2,2-trifluoroacetyl)oxyhexyl] 2,2,2-trifluoroacetate. Molecular Formula: C17H18F6N4O6. Molecular Weight: 488.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528653: 4-Trimethylsiloxy(trimethylsilyl)valerate

Chemical compound data from PubChem database. IUPAC Name: trimethylsilyl 4-trimethylsilyloxypentanoate. Molecular Formula: C11H26O3Si2. Molecular Weight: 262.49. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525869: N,N-Dimethyl-2-phenyl-N'-propyl-acetamidine

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-2-phenyl-N'-propylethanimidamide. Molecular Formula: C13H20N2. Molecular Weight: 204.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400397-T1: [Translated] FEED DEVICE FOR PLATE-SHAPED WORKPIECES

Installation has a laying surface (14) on which plate-shaped workpieces (18) can be placed. A collet chuck (24) with which the workpiece can be gripped, is movable along the feed installation. Said chuck has a holding body (26) and one clamping area (44) away from and one (58) next to its laying surface. The workpiece can be clamped on by moving one of the clamping areas over the other.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
How Do We Build Organizational Capacity in Child Welfare?

How Do We Build Organizational Capacity in Child Welfare?: This brief explores models for building capacity that have been applied in child welfare organizations, including the American Public Human Services Association's Organizational Effectiveness Capacity Building Model, the Interactive Systems Framework, and the Children’s Bureau's Capacity Building Collaborative approach.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, guidance, local, policy, scope
Organization: U.S. Department of Health & Human Services
Patent AT-E401365-T1: [Translated] EMULSIONS OF ORGANOPOLYSILOXANE RESINS PRODUCED BY EMULSION POLYMERIZATION

An aqueous siloxane resin containing emulsion is prepared by: (i) adding water, at least one nonionic surfactant, optionally adding an ionic surfactant, and a catalyst, to a reaction vessel, and heating the contents of the vessel to form a mixture; (ii) adding to the mixture at least one silane monomer of the formula RSi(OR′)3; (iii) optionally, adding to the mixture, silane monomers of the formula R2Si(OR′)2 or R3SiOR′; (iv) allowing the silane monomer to hydrolyze and condense by a polymerization reaction in the catalyzed aqueous mixture; (v) terminating the reaction by neutralizing the mixture; and (vi) recovering from the mixture a siloxane resin emulsion containing a siloxane resin.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
National Study of the Incidence of Child Abuse and Neglect 1980 (NIS-1)

Conducted by NCCAN and mandated by Congress, this study was the first large scale effort to assemble information, based on standardized definitions, about the scope and character of recognized child abuse and neglect in the United States.  From findings obtained in a probability sample of 26 counties in 10 states, national estimates were derived from the numbers and characteristics of abused and neglected children who were: a) referred to CPS agencies and treatment, b) not referred to CPS but were known to other investigatory agencies which may handle abuse/neglect situations (e.g., police, court, public health departments, etc.), or c) were not known to any of the investigatory agencies but were identifiable from other community institutions, particularly schools and hospitals.

Investigators: National Center on Child Abuse and Neglect

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
NSDUH 2022 Person Level Sampling Weight Report

Learn about the techniques used to create weights for the 2022 National Survey on Drug Use and Health (NSDUH) at the person level. The report reviews the generalized exponential model (GEM) used in weighting, discusses potential predictor variables, and details the practical steps used to implement GEM. The report also details the weight calibrations, and presents the evaluation measures of the calibrations, as well as a sensitivity analysis.Chapters:Introduces the survey and the remainder of the report.Reviews the impact of multimode data collection on weighting.Briefly describes of the generalized exponential model.Describes the predictor variables for the model calibration.Defines extreme weights.Discusses control totals for poststratification adjustments.Discusses weight calibration at the dwelling unit level.Discusses weight calibration at the person level.Presents the evaluation measures of calibrated weights and a sensitivity analysis of selected prevalence estimates.Explains the break-off analysis weights.Appendices include technical details about the model and the evaluations that were performed.

Tags: nsduh-2022, samhsa, sampling-weights, substance-use, survey-methodology
Organization: U.S. Department of Health & Human Services
2012 Uniform Reporting System (URS) Tables for New Hampshire

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2012. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, noms-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services