AndreaBozzo/ceres-open-data-index huggingface dataset:
Compound 527327: Methyl 2-[4-methoxy-3-(trifluoromethyl)anilino]pyridine-3-carboxylate

Chemical compound data from PubChem database. IUPAC Name: methyl 2-[4-methoxy-3-(trifluoromethyl)anilino]pyridine-3-carboxylate. Molecular Formula: C15H13F3N2O3. Molecular Weight: 326.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Table 9. Alcohol Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Table 9. Alcohol Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2010, 2011, and 2012 NSDUHs

Tags: adolescent-alcohol, alcohol-use, nsduh-survey, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Compound 525166: Ethyl decyl terephthalate

Chemical compound data from PubChem database. IUPAC Name: 4-O-decyl 1-O-ethyl benzene-1,4-dicarboxylate. Molecular Formula: C20H30O4. Molecular Weight: 334.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2019-2020 National Survey on Drug Use and Health: Guide to State Tables and Summary of Small Area Estimation Methodology

State estimates for these years are no longer available due to methodological concerns with combining 2019 and 2020 data. We apologize for any inconvenience or confusion this may causeBecause of the COVID-19 pandemic, most respondents answered the survey via the web in Quarter 4 of 2020, even though all responses in Quarter 1 were from in-person interviews. It is known that people may respond to the survey differently while taking it online, thus introducing what is called a mode effect.When the state estimates were released, it was assumed that the mode effect was similar for different groups of people. However, later analyses have shown that this assumption should not be made. Because of these analyses, along with concerns about the rapid societal changes in 2020, it was determined that averages across the two years could be misleading.For more detail on this decision, see the 2019-2020state data page.

Tags: drug-use, mental-health, national-survey, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Laparoscopic management of fallopian tube prolapse masquerading as adenocarcinoma of the vagina in a hysterectomized woman

Background
          Fallopian tube prolapse as a complication of abdominal hysterectomy is a rare occurrence. A case with fallopian tube prolapse was managed by a combined vaginal and laparoscopic approach and description of the operative technique is presented.
        
        
          Case presentation
          A 39-year-old woman with vaginal prolapse of the fallopian tube after total abdominal hysterectomy presented with an incorrect diagnosis of adenocarcinoma of the vaginal apex. The prolapsed tube and cystic ovary were removed by vaginal and laparoscopic approach. The postoperative course went well.
        
        
          Conclusions
          Early or late fallopian tube prolapse can occur after total abdominal hysterectomy and vaginal hysterectomy. Symptoms consist of persistent blood loss or leukorrhea, dyspareunia and chronic pelvic pain. Vaginal removal of prolapsed tube with laparoscopic surgery may be a suitable treatment. The abdominal or vaginal approach used in surgical correction of prolapsed tubes must be decided in each case according to the patient's individual characteristics.

Tags: fallopian-tube-prolapse, hysterectomy-complications, laparoscopic-surgery, nih, vaginal-prolapse
Organization: U.S. Department of Health & Human Services
National Survey of Substance Abuse Treatment Facilities (N-SSATS): 2016, Data on Substance Abuse Treatment Facilities

The 2016 National Survey of Substance Abuse Treatment Services (N-SSATS) was conducted between March and November 2016, with a reference date of March 31, 2016. It is the 39th in a series of national surveys begun in the 1970s. The surveys were designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and servicesthroughout the 50 states, the District of Columbia, and other U.S. jurisdictions. The Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration (SAMHSA), U.S. Department of Health and Human Services, plans and directs N-SSATS. This report presents tabular information and highlights from the 2016 N-SSATS.

Tags: addiction-services, behavioral-health, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Impact factors of dermatological journals for 1991 – 2000

Background
          The impact factors of scientific journals are interesting but not unproblematic. It is speculated that the number of journals in which citations can be made correlates with the impact factors in any given speciality.
        
        
          Methods
          Using the Journal Citation Report (JCR) for 1997, a bibliometric analysis was made to assess the correlation between the number of journals available in different fields of clinical medicine and the top impact factor. A detailed study was made of dermatological journals listed in the JCR 1991–2000, to assess the relevance of this general survey.
        
        
          Results
          Using the 1997 JCR definitions of speciality journals, a significant linear correlation was found between the number of journals in a given field and the top impact factor of that field (rs = 0.612, p < 0.05).
          Studying the trend for dermatological journals 1991 to 2000 a similar pattern was found. Significant correlations were also found between total number of journals and mean impact factor (rs = 0.793, p = 0.006), between the total number of journals and the top impact factor (rs = 0.759, p = 0.011) and between the mean and the top impact factor (rs = 0.827, p = 0.003).
        
        
          Conclusions
          The observations suggest that the number of journals available predict the top impact factor. For dermatology journals the top and the mean impact factor are predicted. This is in good agreement with theoretical expectations as more journals make more print-space available for more papers containing citations. It is suggested that new journals in dermatology should be encouraged, as this will most likely increase the impact factor of dermatological journals generally.

Tags: bibliometric-analysis, dermatology-journals, impact-factor, journal-citation-report, nih
Organization: U.S. Department of Health & Human Services
Compound 525490: 1,1-Dimethylpropyl propargyl sulfide

Chemical compound data from PubChem database. IUPAC Name: 2-methyl-2-prop-2-ynylsulfanylbutane. Molecular Formula: C8H14S. Molecular Weight: 142.26. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Kansas: 2011-2012 NSDUH

This report presents Kansas\'s estimates for 25 measures of substance use and mental health based on the combined 2011 and 2012 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided by State and for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: kansas-health, mental-health, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
The spectrum of β-thalassemia mutations in the Arab populations

The Arab countries encompass a wide region stretching from the Persian Gulf to the Atlantic Ocean. The Arab population is quite heterogeneous and has experienced various invasions and migrations throughout history.
β-thalassemia is endemic in all countries of the Arab world. Our review of the molecular basis of β-thalassemia in various Arab countries reveals
the presence of 52 mutations, which are mostly of Mediterranean and Asian origin. The distribution of mutations reflects the geographical and historical
backgrounds of each region. However, no specific mutation is confined to the Arabs, although some Arab countries do have unique mutations.

Tags: arab-populations, beta-thalassemia, genetic-mutations, hemoglobinopathies, nih
Organization: U.S. Department of Health & Human Services
Cell fate decision: T-helper 1 and 2 subsets in immune responses

After activation CD4+ helper T cells differentiate into T-helper (Th) 1 or Th2 effector cells. These two subsets are characterized by their distinct cytokine expression pattern and the immune function they mediate. Over the past years, a number of factors have been identified to affect helper T cell lineage determination, including antigen receptor, coreceptors and, most importantly, cytokine environment. In this review, we also summarize recent advancement in understanding of transcriptional and signaling regulation of the differentiation process. This knowledge will become important in the future to develop means in treating immune disorders.

Tags: cytokine-expression, immune-response-regulation, nih, t-helper-cells, th1-th2-differentiation
Organization: U.S. Department of Health & Human Services
Miami - Fort Lauderdale Div: Drug-Related Emergency Department Visits, 2008-2011 - Underage Drinking

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving underage drinking in the Fort Lauderdale division of the Miami metropolitan area, covering 2008-2011.  Underage drinking includes ED visits that involve alcohol use (alone or with other drugs) for patients under the age of 21.

Tags: alcohol-related-visits, emergency-department, miami-fort-lauderdale, samhsa, underage-drinking
Organization: U.S. Department of Health & Human Services
Compound 525589: N,N-Dimethyl-N'-(4-bromophenyl)-p-methylbenzamidine

Chemical compound data from PubChem database. IUPAC Name: N'-(4-bromophenyl)-N,N,4-trimethylbenzenecarboximidamide. Molecular Formula: C16H17BrN2. Molecular Weight: 317.22. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528352: 5-Methoxyadamantan-2-one

Chemical compound data from PubChem database. IUPAC Name: 5-methoxyadamantan-2-one. Molecular Formula: C11H16O2. Molecular Weight: 180.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527301: sec-Butylmesitylene

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-yl-1,3,5-trimethylbenzene. Molecular Formula: C13H20. Molecular Weight: 176.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Results from the 2013 National Survey on Drug Use and Health: Summary of National Findings

This report presents results from the 2013 National Survey on Drug Use and Health (NSDUH). The report includes national estimates of rates of initiation and use of illicit drugs (e.g., marijuana, cocaine, heroin, hallucinogens, inhalants, and the nonmedical use of prescription-type pain relievers, tranquilizers, stimulants, and sedatives), alcohol, and tobacco products and rates of driving under the influence of drugs or alcohol. The report also covers substance use treatment need/receipt and youth risk and prevention measures. Results are provided for age group, gender, pregnancy status, race/ethnicity, education level, employment status, geographic area, parole/probation status. Comparisons are made between 2013 and 2002 to 2012.

Tags: alcohol-consumption, drug-use, mental-health, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Genogram – Family Relationship Diagram

Family relationship diagramming or genograms provide a visual tool for charting basic family structure and exploring family and case relationships across time. The genogram can be useful in gathering information about family members, understanding relationship dynamics and behavioral patterns, conducting assessments, exploring placement and family support options, and guiding casework to useful and needed interventions. Title IV-E agencies can use genograms as tools in both assessment and intervention.

This webinar features Indiana and Ohio as they describe their experiences in using genograms to aid in child welfare practice. The states shared programmatic and technical challenges, risks, benefits and lessons learned integrating genogram functionality into their child welfare systems.
Additionally, Ohio demonstrated their genogram functionality.

The speakers were:

Indiana

Ohio

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, behavioral, intervention, tool, work
Organization: U.S. Department of Health & Human Services
Compound 525357: 1,2-Dithiepane

Chemical compound data from PubChem database. IUPAC Name: dithiepane. Molecular Formula: C5H10S2. Molecular Weight: 134.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2012 State Profile - Arkansas

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) annual report showing the state profile for Arkansas in 2012. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: arkansas, n-ssats, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Florida (FL)

This report presents Florida\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for Florida for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: florida-health, mental-health, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
2017 Uniform Reporting System (URS) Table for Delaware

This is the 2017 Uniform Reporting System (URS) Output Tables for Delaware. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, evidence-based-practices, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 528353: Adamantane, 1-(1-piperazinyl)

Chemical compound data from PubChem database. IUPAC Name: 1-(1-adamantyl)piperidine. Molecular Formula: C15H25N. Molecular Weight: 219.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Table 10. Binge Alcohol Use in the Past Month among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past month binge alcohol use by persons aged 12 or older by State and substate regions.

Tags: alcohol-use, binge-drinking, nsduh, samhsa, substate-data
Organization: U.S. Department of Health & Human Services
2017 Uniform Reporting System (URS) Table for North Dakota

This is the 2017 Uniform Reporting System (URS) Output Tables for North Dakota. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, noms-measures, north-dakota, samhsa
Organization: U.S. Department of Health & Human Services
The 'four principles of bioethics' as found in 13

Background
          There have been different ethical approaches to the issues in the history of philosophy. Two American philosophers Beachump and Childress formulated some ethical principles namely 'respect to autonomy', 'justice', 'beneficence' and 'non-maleficence'. These 'Four Principles' were presented by the authors as universal and applicable to any culture and society. Mawlana, a great figure in Sufi tradition, had written many books which not only guide people how to worship God to be close to Him, but also advise people how to lead a good life to enrich their personality, as well as to create a harmonious society and a peaceful world.
        
        
          Methods
          In this study we examined the major works of Mawlana to find out which of these 'Four Principles of Bioethics' exist in Mawlana's ethical understanding.
        
        
          Results
          We have found in our study that all these principles exist in Mawlana's writings and philosophy in one form or another.
        
        
          Conclusions
          We have concluded that, further to Beachump and Childress' claim that these principles are universal and applicable to any culture and society, these principles have always existed in different moral traditions in different ways, of which Mawlana's teaching might be presented as a good example.

Tags: autonomy, bioethics, ethical-principles, moral-philosophy, nih
Organization: U.S. Department of Health & Human Services
Hepatic adverse events during highly active antiretroviral therapy containing nevirapine: a case report

Background
          Hepatotoxicity is one of the most serious complications of highly active antiretroviral therapy (HAART). The aim of this report is to analyse an HIV infected patient on HAART including nevirapine and taking antidepressive agents, with acute toxic hepatitis.
        
        
          Case presentation
          A 39 year old patient diagnosed as HIV positive one month ago administered to the clinical ward of the Department of Infectious Diseases and Clinical Microbiology in Ege University Medical School with high fever, malaise, nausea, diarrheae and elevated liver enzymes (ALT 1558 U/L, AST 4288 U/L). He has been using HAART including zidovudine+lamivudine (2 × 1/day) and nevirapine (2 × 200 mg/day, following dose escalation) for 22 days, sertralin and diazepam for 12 days and lithium for 10 days.
          The patient was hospitalized. Antiretroviral and antidepressant treatments were stopped. The day after admission, his fever dropped and his symptoms improved. Clinical improvement continued on the following days. The patient was discharged upon his request on the 14th day of hospitalization. The liver function tests returned to normal levels in two weeks following discharge.
        
        
          Conclusion
          Close monitoring of liver enzymes during the first 12 weeks of nevirapine therapy is critical to prevent life threatening events.

Tags: adverse-drug-reaction, antiretroviral-therapy, hiv-aids, nevirapine-hepatotoxicity, nih
Organization: U.S. Department of Health & Human Services
Cluster-Rasch models for microarray gene expression data

Background
          We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to investigate whether a cluster of genes with similar expression profiles is related to the observed phenotypes; this model can also be used for future prediction. The other formulation provides an alternative way of identifying genes that are over- or underexpressed from their expression levels in tissue or cell samples of a given tissue or cell type.
        
        
          Results
          We illustrate the methods on available datasets of a classification of acute leukemias and of 60 cancer cell lines. For tumor classification, the results are comparable to those previously obtained. For the cancer cell lines dataset, we found four clusters of genes that are related to drug response for many of the 90 drugs that we considered. In addition, for each type of cell line, we identified genes that are over- or underexpressed relative to other genes.
        
        
          Conclusions
          The cluster-Rasch model provides a probabilistic model for describing gene expression patterns across samples and can be used to relate gene expression profiles to phenotypes.

Tags: acute-leukemia, cancer-cell-lines, gene-expression, nih, rasch-model
Organization: U.S. Department of Health & Human Services
2016 Uniform Reporting System (URS) Table for Hawaii

This is the 2016 Uniform Reporting System (URS) Output Tables for Hawaii. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, hawaii, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Racial/Ethnic Differences in Mental Health Service Use Among Adults and Adolescents (2015-2019)

This chartbook uses combined 2015 to 2019 data from the National Survey on Drug Use and Health (NSDUH) to present nationally representative estimates of mental health service utilization among adults aged 18 or older and adolescents aged 12 to 17 within different racial/ethnic groups in the United States. The percentages are annual averages.

Tags: adolescent-mental-health, adult-mental-health, mental-health-services, racial-ethnic-disparities, samhsa
Organization: U.S. Department of Health & Human Services