AndreaBozzo/ceres-open-data-index huggingface dataset:
Program Instruction (PI-10-12)

This Program Instruction (PI) provides instruction on the Fiscal Year (FY) 2011 Federal Medical Assistance Percentage (FMAP) Rates affecting programs under title IV-E of the Social Security Act.

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Tags: data, fiscal, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-04-02)

This Program Instruction (PI) provides instruction to Tribes on the June 30, 2004 submission of: (1) the Child and Family Services Plan (CFSP) Final Report required for title IV-B of the Social Security Act (the Act); (2) the fiscal years (FYs) 2005 - 2009 Child and Family Services Plan for Child Welfare Services and Promoting Safe and Stable Families Programs, and (3) the CFS-101, Parts I and II, Annual Budget Request and Annual Summary of Child and Family Services.

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Tags: fiscal, guidance, instruction, policy, reporting
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-17-04)

This Information Memorandum (IM) supersedes ACYF-CB-IM-02-06 issued May 23, 2002 which addressed procedures for requesting extensions of child welfare waiver demonstrations. This IM alerts title IV-E agencies to updated and streamlined procedures that the Department of Health and Human Services will follow in considering requests to extend child welfare waiver demonstration projects approved under the authority of section 1130 of the Social Security Act.

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Tags: child, guidance, policy, regulation, social
Organization: U.S. Department of Health & Human Services
Action Transmittal (AT-80-05)

This Action Transmittal (AT) provides information on:

(1) Potential Reallotment of Unused Funds from Regular FY 1980 Budget
(2) Apportionment to States and Territories of funds for Fiscal Year 1980

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Tags: data, fiscal, policy, scope, social
Organization: U.S. Department of Health & Human Services
Editorial comment

In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal
		  experiment showing that calcitonin precursors (predominantly procal-citonin)
		  are elevated in proportion to the severity of bacterial sepsis. They conclude
		  that procalcitonin, the major calcitonin precursor, is a good indicator of the
		  activity and severity of the inflammatory response and may be used for
		  monitoring bacterial infections.

Tags: editorial-comment, health-data, nih, opinion-piece
Organization: U.S. Department of Health & Human Services
A p130Castyrosine phosphorylated substrate domain decoy disrupts v-Crk signaling

The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has a substrate domain with up to 15 tyrosines that are potential kinase substrates, able to serve as docking sites for proteins with SH2 or PTB domains. Cas interacts with focal adhesion plaques and is phosphorylated by the tyrosine kinases FAK and Src. A number of effector molecules have been shown to interact with Cas and play a role in its function, including c-crk and v-crk, two adaptor proteins involved in intracellular signaling. Cas function is dependent on tyrosine phosphorylation of its substrate domain, suggesting that tyrosine phosphorylation of Cas in part regulates its control of adhesion and migration. To determine whether the substrate domain alone when tyrosine phosphorylated could signal, we have constructed a chimeric Cas molecule that is phosphorylated independently of upstream signals.

Tags: cell-adhesion, kinase-substrates, nih, p130cas-protein, tyrosine-phosphorylation
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-01-01)

This Information Memorandum (IM) provides the amendment to ACYF-CB-IM-00-01, December 28, 2000, to correct the methodology for calculating foster care re-entries.

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Tags: care, data, foster, guidance, policy
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-87-31)

This Information Memorandum (IM) provides information on the interest and late payment penalties charged for debts owed to the Federal Government resulting from debts arising under titles IV-B and IV-E of the Social Security Act.

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Tags: debt, federal, guidance, policy, social
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-90-18)

This Information Memorandum (IM) establishes FY 1990 allotments for title IV-B and procedures for applying for: (1) A State's 1990; (2) reallotted IV-B funds and (3) funds to be transferred from title IV-E foster care. Share of funds available under title IV-B in FY.

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Tags: child, data, foster, guidance, policy
Organization: U.S. Department of Health & Human Services
PersistentChlamydiaeand chronic arthritis

AllChlamydiaspecies are obligate intracellular bacterial parasites, and all are pathogenic to their various hosts [1].Chlamydia trachomatisandChlamydia pneumoniaeare human pathogens; the former being the etiologic agent for trachoma as well as a prevalent sexually transmitted bacterium, whileC. pneumoniaeis a respiratory pathogen responsible for community-acquired pneumonia. Both species disseminate from their sites of primary infection, and when they do so these organisms often take up long-term residence at distant anatomic locations. At sites of their dissemination, neitherC. trachomatisnorC. pneumoniaeproduces any known toxins. Rather, both species may elicit a powerful immunopathogenic response that in turn can engender various diseases, one of which is inflammatory arthritis [2]. In some individuals with acuteChlamydia-associated arthritis, the disease can become chronic. This article focuses on chronic arthritides attributable, or potentially attributable, to disseminated, persistent infection by theChlamydiae, and is intended primarily to stimulate discussion among researchers and clinicians regarding the unusual biology of these pathogens in relation to chronic disease. It is also intended to elicit discussion as to how knowledge of the biological attributes of chlamydial persistence might influence development of new therapies for treatment of that disease.

Tags: chlamydia-trachomatis, chronic-infection, nih, reactive-arthritis, synovial-tissue
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-19-04)

This Program Instruction (PI) provides guidance to Indian Tribes, Indian Tribal Organizations and Indian Tribal Consortia (hereafter “tribes,” unless otherwise noted) on actions they are required to take to receive their allotments for Federal Fiscal Year (FY) 2020 (subject to the availability of appropriations) authorized under title IV-B, subparts 1 and 2, and Chafee and ETV programs.

PI-19-04 (PDF)

Fiscal Year 2018 Allotment Title IV-B Subpart 1 Stephanie Tubbs Jones Child Welfare Services
Fiscal Year 2018 Allotment Title IV-B Subpart 2 Promoting Safe and Stable Families
Fiscal Year 2018 Allotment for Chafee Foster Care Program for Successful Transition to Adulthood
Fiscal Year 2018 Allotment for Education and Training Vouchers

CFS-101 Instructions, Part I, II, and III Instructions

Part I: Annual Budget Request for Title IV-B, Subpart 1 & 2 Funds, Chafee, and ETV Instructions
Part II: Annual Estimated Expenditure Summary of Child and Family Services Instructions
Part III: Expenditures for Title IV-B, Subparts 1 and 2, Chafee Foster Care Independence (Chafee) and Education and Training Voucher (ETV) Programs Instructions

CFS-101 Forms, Parts I, II and III Excel Workbook (XLSX) (40 KB)

CFS-101 Forms Part I
CFS-101 Forms Part II
CFS-101 Forms Part III

Assurances and Certifications

Title IV-B, subpart 1 and 2 (PDF  (PDF)- 77 KB)
Chafee (PDF  (PDF)- 186 KB)
ETV (PDF  (PDF)- 102 KB)

CB Regional Program Managers

Notification of Adoption Savings Calculation Method

Annual Reporting of Education and Training Vouchers Awarded

Certification of Tribal Population Under Age 21

Tribal CFSP (Optional) Template for FYs 2020-2024 (Word  (DOCX)- 44 KB)

Tribal Training Plan (Optional) Template (Word  (DOCX)- 18 KB)

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Tags: child, fiscal, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-16-01)

This Information Memorandum (IM) informs state title IV-E agencies and tribes about the publication of the Adoption and Foster Care Analysis and Reporting System (AFCARS) Supplemental Notice of Proposed Rule Making (SNPRM) and where to submit comments.

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Tags: adoption, foster, mental, policy, reporting
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-01-03)

This Program Instruction (PI) provides instruction to state on the June 30, 2001 submission of the Annual Progress and Services Report required for: title IV-B of the Social Security Act (the Act), the Child Abuse Prevention and Treatment Act, and the Chafee Foster Care Independence Program; and the CFS-101, Annual Budget Request and Annual Summary of Child and Family Services.

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Tags: abuse, compliance, foster, prevention, reporting
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-81-02)

This Program Instruction (PI) provides instruction for the State Plan Preprint for a Title IV-E Program. Effective August 29, 1988, the guidance in this PI has been superseded by ACYF-CB-PI-88-07.

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Tags: child, guidance, instruction, policy, scope
Organization: U.S. Department of Health & Human Services
BETA-Time Series International Trade: Monthly U.S. Imports by Department of Agriculture Code

The Census data API provides access to the most comprehensive set of data on current month and cumulative year-to-date imports broken down by agricultural and nonagricultural commodities.  The USDA endpoint in the Census data API provides value, shipping weight, and method of transportation totals at the district level for all U.S. trading partners. The Census data API will help users research new markets for their products, establish pricing structures for potential export markets, and conduct economic planning. If you have any questions regarding U.S. international trade data, please call us at 1(800)549-0595 option #4 or email us at eid.international.trade.data@census.gov.

Tags: census
Organization: Department of Commerce
Patent AT-E401808-T1: [Translated] DEVICE FOR ADJUSTING THE LENGTH OF A BRACELET, BRACELET COMPRISING SUCH A DEVICE, AND WATCH EQUIPPED WITH SUCH A BRACELET

The device (28) has a base plate (24) and adjusting links (30) provided at respective longitudinal ends, where one of the links is articulated on the base plate through a rod (32). The rod is articulated on the base plate through a main axle (A1) and on the link through a secondary axle (A2), in which the links are arranged in a manner to slide relative to the plate. A locking device (58) permits the link to grip an anchoring element (60) that is arranged on the plate along two indexed longitudinal positions defining two lengths of strap, respectively.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-10-11)

This Program Instruction (PI) provides instruction on the Fostering Connections to Success and Increasing Adoptions Act of 2008 (Public Law 110-351) Comprehensive Guidance, Titles IV-B and IV-E Plan Requirements, Title IV-E Plan Amendment – Definition of “Child”, Extension of Title IV-E Assistance, Patient Protection and Affordable Care Act (Public Law (P.L.) 111-148).

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Tags: adoption, foster, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Noninferiority trials

In one of the biggest dilemmas facing cardiovascular clinical research, clinical trials are increasingly being required to show benefits on clinical end-points rather than surrogate end-points, while at the same time the incremental benefits of newer treatments are getting smaller. These two factors have a huge impact on sample size, which has led some investigators to design trials to show that the new treatment has an effect similar to that of the standard, rather than outright superiority. Recent examples of fibrinolytic trials that have demonstrated similar effects of two drugs are ASSENT (Assessment of the Safety and Efficacy of a New Thrombolytic)-2, GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries)-III, and COBALT (Continuous Infusion Versus Double-Bolus Administration of Alteplase) [1,2,3,4]. However, as discussed by several authors [5,6,7,8], there are issues with trials of this type that make them considerably less credible than superiority trials.

Tags: assay-sensitivity, clinical-trial-design, nih, noninferiority-trials, treatment-comparison
Organization: U.S. Department of Health & Human Services
Compound 526554: 5-Chloro-N-phenylbenzene-1,2-diamine

Chemical compound data from PubChem database. IUPAC Name: 4-chloro-2-N-phenylbenzene-1,2-diamine. Molecular Formula: C12H11ClN2. Molecular Weight: 218.68. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-11-01)

This Program Instruction (PI) provides guidance for implementing recent changes to the Title IV-E foster care eligibility re-determination policy in a Statewide Automated Child Welfare Information System (SACWIS) environment and the Fostering Connections to Success and Increasing Adoptions Act of 2008 (Fostering Connections) (Public Law (P.L.) 110-351).

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Tags: adoption, foster, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Compound 529845: Dodec-4-enyl acetate

Chemical compound data from PubChem database. IUPAC Name: dodec-4-enyl acetate. Molecular Formula: C14H26O2. Molecular Weight: 226.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-00-01)

This Program Instruction (PI) sets forth the requirements for recipients of Community-Based Family Resource and Support Grant awards for fiscal year 2000, and provides instructions to the States on the Community-Based Family Resource and Support Grant applications.

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Tags: fiscal, grant, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Patent AT-E400095-T1: [Translated] METHOD FOR ASSIGNING AND METHOD FOR ASSOCIATING CODES FOR DATA TRANSMISSIONS BETWEEN A RADIO STATION AND AT LEAST ONE SUBSCRIBER STATION VIA AN AIR INTERFACE OF A RADIO COMMUNICATIONS SYSTEM AND NETWORK-SIDE DEVICE AND R

Chemical patent from PubChem database. Patent Number: AT-E400095-T1. Title: Method of Treatment Using Chemical Compounds. Filing Date: 1999-04-22. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: Methods for treating diseases using specific chemical compounds are provided, including dosing regimens and combination therapies for enhanced therape... IPC Classifications: C07H, A61K, A61P. This patent covers 33 claims related to 8 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Non-detection ofChlamydiaspecies in carotid atheroma using generic primers by nested PCR in a population with a high prevalence ofChlamydia pneumoniaeantibody

The association ofChlamydia pneumoniaewith atherosclerosis is controversial. We investigated the presence ofC. pneumoniaeand otherChlamydiaspp. in atheromatous carotid artery tissue.

Tags: atherosclerosis, carotid-endarterectomy, chlamydia-pneumoniae, nih, polymerase-chain-reaction
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-03-06)

This Program Instruction (PI) provides instruction on the July 31, 2003 submission of State Plan Amendment for Funds under the Educational and Training Vouchers (ETV) Program under the Chafee Foster Care Independence Program - Amendment to Child and Family Services Plan.

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Tags: child, foster, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Compound 528381: 2,5-Dichloro-4-hydroxybenzaldehyde

Chemical compound data from PubChem database. IUPAC Name: 2,5-dichloro-4-hydroxybenzaldehyde. Molecular Formula: C7H4Cl2O2. Molecular Weight: 191.01. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Blood substitutes

Blood substitutes have long been sought after, and artificial oxygen		  carriers may soon become a reality. Despite increased safety of allogeneic		  blood in terms of transmission of infectious diseases [1], avoiding allogeneic blood transfusions remains an important		  goal in perioperative and intensive care medicine. This is because allogeneic		  blood transfusions may cause immunosuppression with an increased incidence of		  postoperative infections [2,3] and		  may adversely affect outcome in intensive care [4], and		  thus they remain a public concern [5].

Tags: blood-substitutes, hemoglobin-based, nih, oxygen-carriers, transfusion-alternatives
Organization: U.S. Department of Health & Human Services
BETA-Time Series International Trade: Monthly U.S. Imports by State and North American Industry Classification System (NAICS)

The Census data API provides access to the most comprehensive set of data on current month and cumulative year-to-date imports by state and North American Industry Classification System (NAICS).  The State NAICS endpoint in the Census data API also provides value, shipping weight, and method of transportation totals at the state level for all U.S. trading partners. The Census data API will help users research new markets for their products, establish pricing structures for potential export markets, and conduct economic planning. If you have any questions regarding U.S. international trade data, please call us at 1(800)549-0595 option #4 or email us at eid.international.trade.data@census.gov.

Tags: census
Organization: Department of Commerce
Compound 529898: 3-(4-Hydroxy-3,5-dimethoxyphenyl)propanal

Chemical compound data from PubChem database. IUPAC Name: 3-(4-hydroxy-3,5-dimethoxyphenyl)propanal. Molecular Formula: C11H14O4. Molecular Weight: 210.23. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-81-01)

This Information Memorandum (IM) provides information on:

1. The State allotments for AFDC-foster care (FC) under either title IV-E or IV-A for FY81
2. Draft estimates of expenditures and statements of expenditures for AFDC-FC and for adoption assistance
3. Draft interim State IV-E plans and IV-A foster care plan amendments

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Tags: adoption, care, child, foster, policy
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-18-10)

This Program Instruction (PI) provides instructions to tribal title IV-E agencies administering or supervising the administration of title IV-E under sections 479B and 471(a) of the Act on the title IV-E prevention program requirements.

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Tags: child, guidance, instruction, policy, prevention
Organization: U.S. Department of Health & Human Services