AndreaBozzo/ceres-open-data-index huggingface dataset:
Publications Using SAMHSA DataNSDUH 2021 Highlighted Population Slides

Use these slides to explore substance use and mental health measures for particular populations in the United States. The slides are based on the 2021 National Survey on Drug Use and Health (NSDUH), which is administered to civilians 12 and older not living in institutions. Within each slide deck, selected estimates are presented overall, by age group, and for selected sub-populations. Slides for the following populations are available:American Indian and Alaska Natives (AIAN)AsiansBlack or African AmericansFemalesHispanics or LatinosMultiracial PeopleNative Hawaiians and Other Pacific Islanders (NHOPI)VeteransThe slides are available as PDF or PowerPoint files.

Tags: mental-health, nsduh-2021, population-health, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Compound 528067: N,O,O-Tris(dimethyl-t-butylsilyl)-l-tyrosine

Chemical compound data from PubChem database. IUPAC Name: [tert-butyl(dimethyl)silyl] 2-[[tert-butyl(dimethyl)silyl]amino]-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]propanoate. Molecular Formula: C27H53NO3Si3. Molecular Weight: 524.0. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528297: Pyrazine, 2-(3-methylpentyl)-3-methoxy

Chemical compound data from PubChem database. IUPAC Name: 2-methoxy-3-(3-methylpentyl)pyrazine. Molecular Formula: C11H18N2O. Molecular Weight: 194.27. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
The Kinship Navigator Program

The Family First Prevention Services Act enacted as part of Public Law (PL) 115 -123, amended Title IV-E to allow title IV-E agencies the option to receive funding for evidence-based kinship navigator programs that meet certain criteria.  Kinship navigator programs help relative and kin caregivers learn about and access programs and services to meet their own needs and the needs of the children they are raising.

Kinship Navigator Programs must meet the requirements described in section 427(a)(1) of the Social Security Act, as follows:

Title IV-E agencies approved to operate the program may claim 50 percent Federal Financial Participation (FFP) for allowable kinship navigator programs.  Title IV-E Kinship Navigator Program requires use of program models that have been reviewed and rated by the Title IV-E Prevention Services Clearinghouse
  
  

 as meeting promising, supported, or well-supported practice standards.

To apply to participate in the program, title IV-E agencies must submit an attachment to their title IV-E plan, following guidance provided in Program Instruction ACYF-CB-PI-18-11.

As of August 2025, there are 12 title IV-E agencies approved to operate an evidence-based kinship navigator program: Colorado, Ohio, Iowa, Minnesota, Nebraska, Nevada, Puerto Rico, South Carolina, Utah, Virginia, Washington.  (Delaware’s plan is being reviewed).

Title IV-E Agency

Title IV-E Kinship Navigator Program Implemented

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: care, fiscal, kinship, policy, prevention
Organization: U.S. Department of Health & Human Services
Compound 528367: 1-(2-(Pyridin-3-yl)pyrrolidin-1-yl)ethanone

Chemical compound data from PubChem database. IUPAC Name: 1-(2-pyridin-3-ylpyrrolidin-1-yl)ethanone. Molecular Formula: C11H14N2O. Molecular Weight: 190.24. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527972: 6-Chloroundecyl acetate

Chemical compound data from PubChem database. IUPAC Name: 6-chloroundecyl acetate. Molecular Formula: C13H25ClO2. Molecular Weight: 248.79. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Trends in Substance Use Disorders Among Adults Aged 18 or Older

This report examines trends in past year substance use disorders among adults aged 18 or older based on the 2002 to 2014 National Survey on Drug Use and Health (NSDUH) data.

Tags: adult-substance-use, mental-health-substance-use, nsduh-data, samhsa, substance-use-disorders
Organization: U.S. Department of Health & Human Services
Compound 525655: p-Bromobenzylidene-(3-ethoxyphenyl)-amine

Chemical compound data from PubChem database. IUPAC Name: 1-(4-bromophenyl)-N-(3-ethoxyphenyl)methanimine. Molecular Formula: C15H14BrNO. Molecular Weight: 304.18. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 526160: Dibutyl 4-cyano-phenyl phosphate

Chemical compound data from PubChem database. IUPAC Name: dibutyl (4-cyanophenyl) phosphate. Molecular Formula: C15H22NO4P. Molecular Weight: 311.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525681: 4-Bromo-N-(4-chlorobenzylidene)aniline

Chemical compound data from PubChem database. IUPAC Name: N-(4-bromophenyl)-1-(4-chlorophenyl)methanimine. Molecular Formula: C13H9BrClN. Molecular Weight: 294.57. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400619-T1: [Translated] USE OF MOO3 AS A CORROSION INHIBITOR AND A COATING COMPOSITION CONTAINING SUCH AN INHIBITOR

Chemical patent from PubChem database. Patent Number: AT-E400619-T1. Title: Sustained Release Formulation. Filing Date: 1995-12-12. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: A sustained release formulation is provided, designed to maintain therapeutic drug levels over extended periods, reducing dosing frequency and improvi... IPC Classifications: A61K, A61P, C07D. This patent covers 29 claims related to 7 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
The mechanisms responsible for 2-dimensional pattern formation in bacterial macrofiber populations grown on solid surfaces: fiber joining and the creation of exclusion zones

Background
          When Bacillus subtilis is cultured in a complex fluid medium under conditions where cell separation is suppressed, populations of multicellular macrofibers arise that mature into ball-like structures. The final sedentary forms are found distributed in patterns on the floor of the growth chamber although individual cells have no flagellar-driven motility. The nature of the patterns and their mode of formation are described in this communication.
        
        
          Results
          Time-lapse video films reveal that fiber-fiber contact in high density populations of macrofibers resulted in their joining either by entwining or supercoiling. Joining led to the production of aggregate structures that eventually contained all of the fibers located in an initial area. Fibers were brought into contact by convection currents and motions associated with macrofiber self-assembly such as walking, pivoting and supercoiling. Large sedentary aggregate structures cleared surrounding areas of other structures by dragging them into the aggregate using supercoiling of extended fibers to power dragging. The spatial distribution of aggregate structures in 6 mature patterns containing a total of 637 structures was compared to that expected in random theoretical populations of the same size distributed in the same surface area. Observed and expected patterns differ significantly. The distances separating all nearest neighbors from one another in observed populations were also measured. The average distance obtained from 1451 measurements involving 519 structures was 0.73 cm. These spacings were achieved without the use of flagella or other conventional bacterial motility mechanisms. A simple mathematical model based upon joining of all structures within an area defined by the minimum observed distance between structures in populations explains the observed distributions very well.
        
        
          Conclusions
          Bacterial macrofibers are capable of colonizing a solid surface by forming large multicellular aggregate structures that are distributed in unique two-dimensional patterns. Cell growth geometry governs in an hierarchical way the formation of these patterns using forces associated with twisting and supercoiling to drive motions and the joining of structures together. Joining by entwining, supercoiling or dragging all require cell growth in a multicellular form, and all result in tightly fused aggregate structures.

Tags: bacillus-subtilis, bacterial-colonies, biofilm-patterns, macrofiber-formation, nih
Organization: U.S. Department of Health & Human Services
CCWIS Data Exchange Requirements Presentation

This DSS presentation describes the Comprehensive Child Welfare Information System (CCWIS) Data Exchange Requirements as defined by Federal Regulations 45 CFR 1355.52(e), 1355.52(f), and 1355.54.  Both mandatory and optional data exchanges are covered in this presentation.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: data, guidance, policy, regulation, reporting
Organization: U.S. Department of Health & Human Services
Patent AT-E400284-T1: [Translated] AGENT FOR SUBSTITUTING BLOOD PLASMA AND PRODUCTION METHOD

The agent for substitution of the blood plasma is made up of the vegetal protein substance edestin, advantageously a product from the hemp seeds. Advantageously, edestin is a component of the solution comprised of 5%-40% in weight of edestin, 0.5%-7% in weight of inorganic substances, 0.5%-7% in weight of organic substances, hormones, and other substances to 100 % in weight of the colloid solution. According to the method of production of an agent for blood plasma substitution, the vegetal seeds are either cold-pressed or ground to powder and extracted under a compressed gas; the pressed out or extracted vegetal oil is separated, the pressed together or extracted seeds to be relieved of fat and decolorized are extracted by action of the organic solvents, the fat relieved and decolorized substance is then filtered out and exposed to action of the inorganic salts in the water solution and at the temperature from 20 ° C. to 60 ° C., the solution is filtered and edestin is finally isolated from the filtrate. Advantageousl hemp seeds are subjected to the cold pressing and grinding processes and to the gas-assisted pressure extraction. Advantageously, the vegetal seeds are being extracted under the compressed carbon dioxide.

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
An efficient method to successively introduce transgenes into a given genomic locus in the mouse

Background
          Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability of well-characterized promoters that direct bona-fide expression of transgenes in transgenic mice is limited. Here we described a method that allows highly efficient targeting of transgenes to a preselected locus in ES cells.
        
        
          Results
          A pgk-LoxP-Neo cassette was introduced into a desired genomic locus by homologous recombination in ES cells. The pgk promoter was then removed from the targeted ES cells by Cre recombinase thereby restoring the ES cells' sensitivity to G418. We demonstrated that transgenes could be efficiently introduced into this genomic locus by reconstituting a functional Neo gene.
        
        
          Conclusion
          This approach is simple and extremely efficient in facilitating the introduction of single-copy transgenes into defined genomic loci. The availability of such an approach greatly enhances the ease of using endogenous regulatory elements to control transgene expression and, in turn, expands the repertoire of elements available for transgene expression.

Tags: es-cells, gene-insertion, gene-targeting, nih, transgenic-mice
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for Maine

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Maine. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, maine, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 529055: 2-Isopropyl-4,6-dimethyldihydro-1,3,5-dithiazine

Chemical compound data from PubChem database. IUPAC Name: 4,6-dimethyl-2-propan-2-yl-1,3,5-dithiazinane. Molecular Formula: C8H17NS2. Molecular Weight: 191.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 527125: 1,6-Dichloro-dibenzothiophene

Chemical compound data from PubChem database. IUPAC Name: 1,6-dichlorodibenzothiophene. Molecular Formula: C12H6Cl2S. Molecular Weight: 253.1. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528192: 1,2-Propanediol, 3-(2-methylphenyloxy), DTBS

Chemical compound data from PubChem database. IUPAC Name: 2,2-ditert-butyl-4-(2-methylphenoxy)-1,3,2-dioxasilolane. Molecular Formula: C17H28O3Si. Molecular Weight: 308.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Video Series on Data Driven Decision Making

This first part of the video series on data-driven decision making (DDDM) provides an overview of DDDM, explains its importance in the context of human service organizations, and describes the process of developing a theory of change as a first step in the DDDM process in the context of a fictional human services organization (Greene County Department of Human Services).

This second part of the DDDM video series explores the process of collecting and analyzing data to inform decision making in a human service context. Using the fictional example of Greene County Department of Human Services’ foster care recruitment and licensing program, the video describes the creation of data collection and tracking systems, the monitoring of ongoing recruitment and licensing activities, and using data to identify and troubleshoot problems.

This third and final part of the DDDM video series describes strategies for communicating information collected through the DDDM process to key stakeholder groups in a clear and concise manner and for using findings to solve problems and make program improvements. The fictional example of Greene County Department of Human Services’ foster care recruitment and licensing program is used again to illustrate these strategies.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: data, human, policy, reporting, scope
Organization: U.S. Department of Health & Human Services
Compound 525123: Propanoic acid, 2,3-dichloropropylester

Chemical compound data from PubChem database. IUPAC Name: 2,3-dichloropropyl propanoate. Molecular Formula: C6H10Cl2O2. Molecular Weight: 185.05. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Adaptations to iron deficiency: cardiac functional responsiveness to norepinephrine, arterial remodeling, and the effect of beta-blockade on cardiac hypertrophy

Background
          Iron deficiency (ID) results in ventricular hypertrophy, believed to involve sympathetic stimulation. We hypothesized that with ID 1) intravenous norepinephrine would alter heart rate (HR) and contractility, 2) abdominal aorta would be larger and more distensible, and 3) the beta-blocker propanolol would reduce hypertrophy.
        
        
          Methods
          1) 30 CD rats were fed an ID or replete diet for 1 week or 1 month. Norepinephrine was infused via jugular vein; pressure was monitored at carotid artery. Saline infusions were used as a control. The pressure trace was analyzed for HR, contractility, systolic and diastolic pressures. 2) Abdominal aorta catheters inflated the aorta, while digital microscopic images were recorded at stepwise pressures to measure arterial diameter and distensibility. 3) An additional 10 rats (5 ID, 5 control) were given a daily injection of propanolol or saline. After 1 month, the hearts were excised and weighed.
        
        
          Results
          Enhanced contractility, but not HR, was associated with ID hypertrophic hearts. Systolic and diastolic blood pressures were consistent with an increase in arterial diameter associated with ID. Aortic diameter at 100 mmHg and distensibility were increased with ID. Propanolol was associated with an increase in heart to body mass ratio.
        
        
          Conclusions
          ID cardiac hypertrophy results in an increased inotropic, but not chronotropic response to the sympathetic neurotransmitter, norepinephrine. Increased aortic diameter is consistent with a flow-dependent vascular remodeling; increased distensibility may reflect decreased vascular collagen content. The failure of propanolol to prevent hypertrophy suggests that ID hypertrophy is not mediated via beta-adrenergic neurotransmission.

Tags: arterial-remodeling, cardiac-hypertrophy, iron-deficiency, nih, norepinephrine-response
Organization: U.S. Department of Health & Human Services
2022 Uniform Reporting System (URS) Table For Arizona

This is the 2022 Uniform Reporting System (URS) Output Tables for Arizona. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: arizona-mental-health, mental-health-services, noms-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Compound 527673: Butanoic acid, 2-chloro, 1,2-dimethylpropyl ester

Chemical compound data from PubChem database. IUPAC Name: 3-methylbutan-2-yl 2-chlorobutanoate. Molecular Formula: C9H17ClO2. Molecular Weight: 192.68. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Development of Dengue virus type 2 replicons capable of prolonged expression in host cells

Background
          As part of a program to develop a Dengue virus vaccine which avoids the deleterious effects of antibody dependent enhancement (ADE) of infection mediated by antibodies to Dengue virus structural proteins, we have begun to investigate the possibility of designing Dengue vaccines based on non-structural proteins.
        
        
          Results
          Dengue constructs which lack major structural proteins replicate intracellularly in tissue culture. These replicons are capable of prolonged expression of Dengue virus non-structural proteins for at least seven days in culture.
        
        
          Conclusions
          Dengue virus genomes lacking major structural proteins can, like other flaviviruses, replicate intracellularly and express virus non-structural proteins with minimal toxicity to host cells. These findings pave the way for the development of dengue virus replicons as a form of live, attenuated virus vaccine.

Tags: dengue-virus, nih, vaccine-development, viral-replicons
Organization: U.S. Department of Health & Human Services
Compound 529900: 6-Methyltetradecane

Chemical compound data from PubChem database. IUPAC Name: 6-methyltetradecane. Molecular Formula: C15H32. Molecular Weight: 212.41. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Guam

This is the 2020 Uniform Reporting System (URS) Output Tables for Guam. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, guam-health-data, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services
2017 Uniform Reporting System (URS) Table for Colorado

This is the 2017 Uniform Reporting System (URS) Output Tables for Colorado. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: colorado-mental-health, community-mental-health, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services