AndreaBozzo/ceres-open-data-index huggingface dataset:
A new device for 100 per cent humidification of inspired air

A new humidifier for use during mechanical ventilation in
			 endotracheally intubated patients is described and tested. The humidifier is
			 based on a heat-moisture exchanger, which absorbs the expired heat and moisture
			 and releases it into the inspired air. External heat and water are then added
			 at the patient side of the heat-moisture exchanger, so that the inspired gas
			 should reach 100% humidity (44 mg/l) at 37°C. In bench tests using constant
			 and decelerating inspiratory flow and minute volumes of 3–25 l the device gave
			 an absolute humidity of 41–44 mg/l, and it reduced the amount of water consumed
			 in eight mechanically ventilated patients compared with a conventional active
			 humidifier. During a 24-h test period there was no water condensation in the
			 ventilator tubing with the new device.

Tags: airway-humidification, heat-moisture-exchanger, mechanical-ventilation, nih, respiratory-therapy
Organization: U.S. Department of Health & Human Services
Association of MHC and rheumatoid arthritis: Why is rheumatoid		  arthritis associated with the MHC genetic region? An introduction

Association of MHC and rheumatoid arthritis: Why is rheumatoid		  arthritis associated with the MHC genetic region? An introduction

Tags: autoimmune-disease, genetic-association, mhc-genes, nih, rheumatoid-arthritis
Organization: U.S. Department of Health & Human Services
Increased risk of traffic accidents in subjects with latent toxoplasmosis: a retrospective case-control study

Background
          The parasite Toxoplasma gondii infects 30–60% of humans worldwide. Latent toxoplasmosis, i.e., the life-long presence of Toxoplasma cysts in neural and muscular tissues, leads to prolongation of reaction times in infected subjects. It is not known, however, whether the changes observed in the laboratory influence the performance of subjects in real-life situations.
        
        
          Methods
          The seroprevalence of latent toxoplasmosis in subjects involved in traffic accidents (N = 146) and in the general population living in the same area (N = 446) was compared by a Mantel-Haenszel test for age-stratified data. Correlation between relative risk of traffic accidents and level of anti-Toxoplasma antibody titre was evaluated with the Cochran-Armitage test for trends.
        
        
          Results
          A higher seroprevalence was found in the traffic accident set than in the general population (Chi2MH = 21.45, p < 0.0001). The value of the odds ratio (OR) suggests that subjects with latent toxoplasmosis had a 2.65 (C.I.95= 1.76–4.01) times higher risk of an accident than the toxoplasmosis-negative subjects. The OR significantly increased with level of anti-Toxoplasma antibody titre (p < 0.0001), being low (OR = 1.86, C.I.95 = 1.14–3.03) for the 99 subjects with low antibody titres (8 and 16), higher (OR = 4.78, C.I.95 = 2.39–9.59) for the 37 subjects with moderate titres (32 and 64), and very high (OR = 16.03, C.I.95 = 1.89–135.66) for the 6 subjects with titres higher than 64.
        
        
          Conclusion
          The subjects with latent toxoplasmosis have significantly increased risk of traffic accidents than the noninfected subjects. Relative risk of traffic accidents decreases with the duration of infection. These results suggest that 'asymptomatic' acquired toxoplasmosis might in fact represent a serious and highly underestimated public health problem, as well as an economic problem.

Tags: accident-risk, case-control-study, nih, toxoplasmosis, traffic-accidents
Organization: U.S. Department of Health & Human Services
2010-2012 NSDUH State-Specific Substate Region Estimates and Maps

This report provides State-specific tables and maps showing substate region prevalence estimates for 25 measures of substance use and mental disorders based on the 2010 to 2012 National Survey on Drug Use and Health (NSDUH). Results include past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older by 362 substate regions within the 50 States and the District of Columbia. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).

Tags: mental-health-estimates, samhsa, state-level-data, substance-use-disorder, suicidal-ideation
Organization: U.S. Department of Health & Human Services
2010 CMHS Uniform Reporting System (URS) Output Tables for Maine

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, community-mental-health, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
2019 Uniform Reporting System (URS) Table for Utah

These are the 2019 Uniform Reporting System (URS) Output Tables for Utah. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, noms-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Interactions between genes and environmental factors in asthma and atopy: new developments

Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in identifying chromosomal regions and polymorphisms in candidate genes linked to or associated with asthma, atopic dermatitis, IgE levels and response to asthma therapy. The aims of this review are to explain the methodology of genetic studies of multifactorial diseases, to summarize chromosomal regions and polymorphisms in candidate genes linked to or associated with asthma and associated traits, to list genetic alterations that may alter response to asthma therapy, and to outline genetic factors that may render individuals more susceptible to asthma and atopy due to environmental changes.

Tags: asthma-genetics, asthma-therapy-response, atopy-environment, gene-environment-interaction, nih
Organization: U.S. Department of Health & Human Services
Trends in smoking among adults with mental health problems. (SR9)

"Although various national data sources have determined that rates of cigarette use have gone down over time this has not been assessed among those with mental health problems. Using NHIS data, we will estimate cigarette use over time among adults with serious psychological distress and adults without psychological distress. NHIS data will be used because of the ability to assess long term trend. That is, psychological distress and cigarette use can be assessed in NHIS from 1997 to 2011. In addition, we will discuss the NHIS estimates in the context of NSDUH data demonstrating that NSDUH also indicates higher rates of cigarette use among those with psychological distress and/or mental illness using 2005 to 2011 data. Furthermore, a discussion of the comparisons of NHIS and NSDUH mental health measures will be included. "Trends in smoking among adults with mental health problems. (SR9)(link is external)

Tags: mental-health, nhis-data, psychological-distress, samhsa, smoking-prevalence
Organization: U.S. Department of Health & Human Services
Is council tax valuation band a predictor of mortality?

Background
          All current UK indices of socio-economic status have inherent problems, especially those used to govern resource allocation to the health sphere. The search for improved markers continues: this study proposes and tests the possibility that Council Tax Valuation Band (CTVB) might match requirements.
        
        
          Presentation of the hypothesis
          To determine if there is an association between CTVB of final residence and mortality risk using the death registers of a UK general practice.
        
        
          Testing the hypothesis
          Standardised death rates and odds ratios (ORs) for groups defined by CTVB of dwelling (A – H) were calculated using one in four denominator samples from the practice lists. Analyses were repeated three times – between number of deaths and CTVB of residence of deceased 1992 – 1994 inclusive, 1995 – 1997 inc., 1998 – 2000 inc.
          In 856 deaths there were consistent and significant differences in death rates between CTVBs: above average for bands A and B residents; below average for other band residents. There were significantly higher ORs for A, B residents who were female and who died prematurely (before average group life expectancy).
        
        
          Implications of the hypothesis
          CTVB of final residence appears to be a proxy marker of mortality risk and could be a valuable indicator of health needs resource at household level. It is worthy of further exploration.

Tags: council-tax-band, death-rates, mortality-risk, nih, socioeconomic-status
Organization: U.S. Department of Health & Human Services
NSDUH 2018 Questionnaire Dwelling Unit-Level and Person Pair-Level Sampling Weight Calibration

NSDUH allows for estimating characteristics at the person level, pair level, and household or QDU level. This report describes the weight calibration methods used for the pair- and QDU-level respondents. As described in the person-level report, NSDUH is an annual survey of about 67,500 people selected from the civilian, noninstitutionalized population aged 12 or older from all 50 states and the District of Columbia. A coordinated sample design was developed for the 2014 through 2018 NSDUHs. The coordinated design facilitated 50 percent overlap in third-stage units (area segments) within each successive 2-year period from 2014 through 2018.

Tags: household-survey, nsduh-survey, samhsa, sampling-weights, substance-use
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Arizona, 2014

This is a behavioral health report for the state of Arizona. It uses the National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use, youth mental health and treatment, adult mental health and treatment, substance use, and substance use treatment for the years 2009 to 2013.

Tags: arizona-behavioral-health, mental-health-arizona, samhsa, substance-use-arizona, youth-behavioral-health
Organization: U.S. Department of Health & Human Services
Experience with prolonged induced hypothermia in severe head injury

Background:
          Recent prospective controlled trials of induced moderate hypothermia (32⌓34°C) for relatively short periods (24⌓48 h) in patients with severe head injury have suggested improvement in intracranial pressure control and outcome. It is possible that increased benefit might be achieved if hypothermia was maintained for more periods longer than 48 h, but there is little in the literature on the effects of prolonged moderate hypothermia in adults with severe head injury. We used moderate induced hypothermia (30⌓33°C) in 43 patients with severe head injury for prolonged periods (mean 8 days, range 2⌓19 days).
        
        
          Results:
          Although nosocomial pneumonia (defined in this study as both new chest radiograph changes and culture of a respiratory pathogen from tracheal aspirate) was quite common (45%), death from sepsis was rare (5%). Other findings included hypokalaemia on induction of hypothermia and a decreasing total white cell and platelet count over 10 days. There were no major cardiac arrhythmias. There was a satisfactory neurological outcome in 20 out of 43 patients (47%).
        
        
          Conclusion:
          Moderate hypothermia may be induced for more prolonged periods, and is a relatively safe and feasible therapeutic option in the treatment of selected patients with severe traumatic brain injury. Thus, further prospective controlled trials using induced hypothermia for longer periods than 48 h are warranted.

Tags: head-injury-outcome, hypothermia-complications, induced-hypothermia, nih, traumatic-brain-injury
Organization: U.S. Department of Health & Human Services
Time between Termination of Parental Rights (TPR) and Adoption Finalization: 10/1/2007 - 9/30/2008

This report provides state-specific data from fiscal year 2008 about the time between the termination of parental rights and the adoption finalization for public agency adoptions.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: adoption, child, data, fiscal, policy
Organization: U.S. Department of Health & Human Services
Compound 525640: N,N-Dimethyl-N'-octyl-p-methoxybenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-methoxy-N,N-dimethyl-N'-octylbenzenecarboximidamide. Molecular Formula: C18H30N2O. Molecular Weight: 290.4. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Supporting Evidence-Based Home Visitation Programs to Prevent Child Abuse and Neglect Project: The Children's Trust Fund of South Carolina

Location:

Columbia, South Carolina

Home Visiting Program Selected:

Nurse Family Partnership

Home Visiting Target Population:

First-time, low income mothers, rural and underserved populations

Project Overview:
With this grant, South Carolina will focus on continuing to develop future NFP sites, particularly in rural and underserved communities, and establishing a comprehensive integrated infrastructure that addresses the currently fragmented home visiting system in the state. This will build on and extend work through outside funding that The Children's Trust Fund of South Carolina recently received to expand their current implementation of Nurse Family Partnership (NFP). Specifically, to expand NFP, South Carolina will: (1) develop outreach plans that identify strategies for addressing the needs of rural and underserved populations, such as Native American mothers; (2) add four to five new NFP sites in communities meeting the criteria of NFP determined readiness; and (3) continue to provide technical assistance to build capacity for future NFP sites. To develop an integrated infrastructure across home visiting programs, The Children’s Trust Fund will collaborate with other organization on developing a state-wide home visitation referral triage system that aims to match families with appropriate services. The proposed evaluation will include an implementation analysis and a pre-post analysis of outcomes.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, grant, home, neglect, policy
Organization: U.S. Department of Health & Human Services
A new prototype of an electronic jet-ventilator and its humidification
		  system

Background:
          Adequate humidification in long-term jet ventilation is a critical
				aspect in terms of clinical safety.
        
        
          Aim:
          To assess a prototype of an electronic jet-ventilator and its
				humidification system.
        
        
          Methods:
          Forty patients with respiratory insufficiency were randomly
				allocated to one of four groups. The criterion for inclusion in this study was
				respiratory insufficiency exhibiting a Murray score above 2. The four groups of
				patients were ventilated with three different respirators and four different
				humidification systems. Patients in groups A and B received superimposed
				high-frequency jet ventilation (SHFJV) by an electronic jet-ventilator either
				with (group A) or without (group B) an additional humidification system.
				Patients in group C received high-frequency percussive ventilation (HFPV) by a
				pneumatic high-frequency respirator, using a hot water humidifier for warming
				and moistening the inspiration gas. Patients in group D received conventional
				mechanical ventilation using a standard intensive care unit respirator with a
				standard humidification system. SHFJV and HFPV were used for a period of 100 h
				(4days).
        
        
          Results:
          A significantly low inspiration gas temperature was noted in
				patients in group B, initially (27.2 ± 2.5°C) and after 2 days
				(28.0 ± 1.6°C) (P < 0.05). The percentage of relative
				humidity of the inspiration gas in patients in group B was also initially
				significantly low (69.8 ± 4.1%; P < 0.05) but rose to an average
				of 98 ± 2.8% after 2 h. The average percentage across all four groups
				amounted to 98 ± 0.4% after 2 h. Inflammation of the tracheal mucosa was
				found in patients in group B and the mucosal injury score (MIS) was
				significantly higher than in all the other groups. Patients in groups A, C and
				D showed no severe evidence of airway damage, exhibiting adequate values of
				relative humidity and temperature of the inspired gas.
        
        
          Conclusion:
          The problems of humidification associated with jet ventilation can
				be fully prevented by using this new jet-ventilator. These data were sustained
				by nondeteriorating MIS values at the end of the 4-day study period in groups
				A, C and D.

Tags: humidification-systems, jet-ventilation, mechanical-ventilation, nih, respiratory-insufficiency
Organization: U.S. Department of Health & Human Services
South Dakota 2016 Annual Progress and Services Report Contact

South Dakota 2016 Annual Progress and Services Report Contact Information:

Merlin Weyer, Assistant DirectorDepartment of Social ServicesDivision of Child Protection Services700 Governors DrivePierre, SD 57501Email: merlin.weyer@state.sd.us

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, data, reporting, scope, social
Organization: U.S. Department of Health & Human Services
Compound 525077: 1-(17-Hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl)ethane-1,2-diol

Chemical compound data from PubChem database. IUPAC Name: 1-(17-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl)ethane-1,2-diol. Molecular Formula: C21H36O3. Molecular Weight: 336.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Results from the 2014 National Survey on Drug Use and Health:  Mental Health Detailed Tables

Results from the 2014 National Survey on Drug Use and Health: Mental Health Detailed Tables is a collection of tables presenting national estimates from the National Survey on Drug Use and Health (NSDUH). These tables present information on past year mental health measures and past year mental health service utilization for youths aged 12 to 17 and adults aged 18 or older. Tables with data on adults include measures on any mental illness (AMI), serious mental illness (SMI), moderate mental illness, low (mild) mental illness, mental health service utilization (i.e., treatment or counseling for mental health issues), suicidal thoughts and behaviors, major depressive episode (MDE), treatment for depression (among adults with MDE), and serious psychological distress (SPD). Tables with data on youths include measures on mental health service utilization, MDE, and treatment for depression (among youths with MDE). Measures related to the co-occurrence of mental disorders with substance use or with substance use disorders (SUDs) also are presented for both adults and youths. Measures of these characteristics and behaviors are presented by a variety of demographic, geographic, and other variables. The estimates in the tables include rates of persons having the characteristics, numbers of persons with these characteristics, and corresponding standard errors. Most of these tables are trend tables presenting estimates from the 2013 and 2014 NSDUHs.

Tags: major-depressive-episode, mental-health, mental-health-services, samhsa, suicidal-ideation
Organization: U.S. Department of Health & Human Services
2018 Uniform Reporting System (URS) Table for Nevada

This is the 2018 Uniform Reporting System (URS) Output Tables for Nevada. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, national-outcome-measures, nevada, samhsa
Organization: U.S. Department of Health & Human Services
Problems in early diagnosis of bladder cancer in a spinal cord injury patient: Report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder

Background
          Typical symptoms and signs of a clinical condition may be absent in spinal cord injury (SCI) patients.
        
        
          Case presentation
          A male with paraplegia was passing urine through penile sheath for 35 years, when he developed urinary infections. There was no history of haematuria. Intravenous urography showed bilateral hydronephrosis. The significance of abnormal outline of bladder was not appreciated. As there was large residual urine, he was advised intermittent catheterisation. Serum urea: 3.5 mmol/L; creatinine: 77 umol/L. A year later, serum urea: 36.8 mmol/l; creatinine: 632 umol/l; white cell count: 22.2; neutrophils: 18.88. Ultrasound: bilateral hydronephrosis. Bilateral nephrostomy was performed. Subsequently, blood tests showed: Urea: 14.2 mmol/l; Creatinine: 251 umol/l; Adjusted Calcium: 3.28 mmol/l; Parathyroid hormone: < 0.7 pmol/l (1.1 – 6.9); Parathyroid hormone-related protein (PTHrP): 2.3 pmol/l (0.7 – 1.8). Ultrasound scan of urinary bladder showed mixed echogenicity, which was diagnosed as debris. CT of pelvis was interpreted as vesical abscess. Urine cytology: Transitional cells showing mild atypia. Bladder biopsy: Inflamed mucosa lined by normal urothelial cells.
          A repeat ultrasound scan demonstrated a tumour arising from right lateral wall; biopsy revealed squamous cell carcinoma. In view of persistently high white cell count and high calcium level, immunohistochemistry for G-CSF and PTHrP was performed. Dense staining of tumour cells for G-CSF and faintly positive staining for C-terminal PTHrP were observed. This patient expired about five months later.
        
        
          Conclusion
          This case demonstrates how delay in diagnosis of bladder cancer could occur in a SCI patient due to absence of characteristic symptoms and signs.

Tags: bladder-cancer, case-report, nih, parathyroid-hormone, spinal-cord-injury
Organization: U.S. Department of Health & Human Services