AndreaBozzo/ceres-open-data-index huggingface dataset:
2010-2012 NSDUH Substate Estimates of Substance Use and Mental Disorders

This report uses 2010 to 2012 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older by 362 substate regions within the 50 States and the District of Columbia. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).

Tags: major-depressive-episode, mental-health-estimates, samhsa, serious-mental-illness, substance-use-disorder
Organization: U.S. Department of Health & Human Services
Compound 528470: 1-Undecene, 2,6,10-trimethyl

Chemical compound data from PubChem database. IUPAC Name: 2,6,10-trimethylundec-1-ene. Molecular Formula: C14H28. Molecular Weight: 196.37. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Missouri

This is the 2021 Uniform Reporting System (URS) Output Tables for Missouri. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, missouri-mental-health, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 528450: 1-Hexadecene, 2,7,11,15-tetramethyl

Chemical compound data from PubChem database. IUPAC Name: 2,7,11,15-tetramethylhexadec-1-ene. Molecular Formula: C20H40. Molecular Weight: 280.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525404: 2-Methyl-3,5-dithiahexane

Chemical compound data from PubChem database. IUPAC Name: 2-(methylsulfanylmethylsulfanyl)propane. Molecular Formula: C5H12S2. Molecular Weight: 136.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Understanding childhood asthma in focus groups: perspectives from mothers of different ethnic backgrounds

Background
          Diagnosing childhood asthma is dependent upon parental symptom reporting but there are problems in the use of words and terms. The purpose of this study was to describe and compare understandings of childhood 'asthma' by mothers from three different ethnic backgrounds who have no personal experience of diagnosing asthma. A better understanding of parents' perceptions of an illness by clinicians should improve communication and management of the illness.
        
        
          Method
          Sixty-six mothers living in east London describing their ethnic backgrounds as Bangladeshi, white English and black Caribbean were recruited to 9 focus groups. Discussion was semi-structured. Three sessions were conducted with each ethnic group. Mothers were shown a video clip of a boy with audible wheeze and cough and then addressed 6 questions. Sessions were recorded and transcribed verbatim. Responses were compared within and between ethnic groups.
        
        
          Results
          Each session, and ethnic group overall, developed a particular orientation to the discussion. Some mothers described the problem using single signs, while others imitated the sound or made comparisons to other illnesses. Hereditary factors were recognised by some, although all groups were concerned with environmental triggers. Responses about what to do included 'normal illness' strategies, use of health services and calls for complementary treatment. All groups were concerned about using medication every day. Expectations about the quality of life were varied, with recognition that restrictions may be based on parental beliefs about asthma, rather than asthma itself.
        
        
          Conclusion
          Information from these focus groups suggests mothers know a great deal about childhood asthma even though they have no personal experience of it. Knowledge of how mothers from these ethnic backgrounds perceive asthma may facilitate doctor – patient communication with parents of children experiencing breathing difficulties.

Tags: childhood-asthma, ethnic-groups, focus-groups, maternal-perception, nih
Organization: U.S. Department of Health & Human Services
2012 State Profile - District of Columbia

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) annual report showing the state profile for District of Columbia in 2012. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: behavioral-health-services, district-of-columbia, n-ssats, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
Predictors of refusal to participate: a longitudinal health survey of the elderly in Australia

Background
          The loss of participants in longitudinal studies due to non-contact, refusal or death can introduce bias into the results of such studies. The study described here examines reasons for refusal over three waves of a survey of persons aged ≥ 70 years.
        
        
          Methods
          In a longitudinal study involving three waves, participants were compared to those who refused to participate but allowed an informant to be interviewed and to those who refused any participation.
        
        
          Results
          At Wave 1 both groups of Wave 2 non-participants had reported lower occupational status and fewer years of education, had achieved lower verbal IQ scores and cognitive performance scores and experienced some distress from the interview. Those with an informant interview only were in poorer physical health than those who participated and those who refused. Depression and anxiety symptoms were not associated with non-participation. Multivariate analyses found that verbal IQ and cognitive impairment predicted refusal. Results were very similar for refusers at both Waves 2 and 3.
        
        
          Conclusions
          Longitudinal studies of the elderly may over estimate cognitive performance because of the greater refusal rate of those with poorer performance. However, there is no evidence of bias with respect to anxiety or depression.

Tags: cognitive-decline, elderly-health, longitudinal-study, nih, survey-refusal
Organization: U.S. Department of Health & Human Services
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator

Background
          Endoplasmic reticulum retention of misfolded cystic fibrosis transmembrane conductance regulator (CFTR) mutants and their rapid degradation is the major cause of cystic fibrosis (CF). An important goal is to understand the mechanism of how the misfolded proteins are recognized, retained, and targeted for degradation.
        
        
          Results
          Using a web-based algorithm, PESTFind, we found a PEST sequence in the regulatory (R) domain of CFTR. The PEST sequence is found in many short-lived eukaryotic proteins and plays a role in their degradation. To determine its role in the stability and degradation of misprocessed CFTR, we introduced a number of site-directed mutations into the PEST sequence in the cDNA of ΔF508 CFTR, the most prevalent misprocessed mutation found in CF patients. Analysis of these mutants showed that the disruption of the PEST sequence plays a minor role in the degradation of the CFTR mutants. Multiple mutations to the PEST sequence within the R domain of CFTR inhibit maturation of CFTR and prevent the formation of a 100 kDa degradation product. The mutations, however, do not improve the stability of the mutant ΔF508 CFTR.
        
        
          Conclusion
          These observations show that disruption of the structure of the R domain of CFTR can inhibit maturation of the protein and that the predicted PEST sequence plays no significant role in the degradation of CFTR.

Tags: cftr-protein, cystic-fibrosis, nih, pest-sequence, protein-degradation
Organization: U.S. Department of Health & Human Services
Kansas (KS)

This report uses 2008 to 2010 National Survey on Drug Use and Health (NSDUH) to assess past year alcohol use disorder and illicit drug use disorder among persons aged 12 or older for Kansas overall and for substate regions within Kansas. Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE).

Tags: kansas-health, mental-health-indicators, nsduh-data, samhsa, substance-use-disorder
Organization: U.S. Department of Health & Human Services
Glucosinolate breakdown products as insect fumigants and their effect on carbon dioxide emission of insects

Background
          Glucosinolate breakdown products are volatile, therefore good candidates for insect fumigants. However, although they are insecticidal, the mode of action of such natural products is not clear. We studied the insecticidal effect of these compounds as fumigants, and monitored the production of carbon dioxide by the insects as a probe to the understanding of their mode of action.
        
        
          Results
          The fumigation 24-h LC50 against the house fly (Musca domestica L.) of allyl thiocyanate, allyl isothiocyanate, allyl cyanide, and l-cyano-2-hydroxy-3-butene was 0.1, 0.13, 3.66, and 6.2 μg cm-3, respectively; they were 0.55, 1.57, 2.8, and > 19.60 μg cm-3, respectively, against the lesser grain borer (Rhyzopertha dominica Fabricius). The fumigation toxicity of some of the glucosinolate products was very close to or better than that of the commercial insect fumigants such as chloropicrin (LC50: 0.08 and 1.3 μg cm-3 against M. domestica and R. dominica, respectively) and dichlorovos (LC50: < 0.02 and 0.29 μg cm-3 against M. domestica and R. dominica, respectively) in our laboratory tests. Significantly increased CO2 expiration was found in insects exposed to the vapor of allyl isothiocyanate, allyl thiocyanate and allyl isocyanate. Allyl isothiocyanate was also found to increase the CO2 expiration of the American cockroach (Periplaneta americana L.).
        
        
          Conclusions
          Glucosinolate breakdown products have potential as biodegradable and safe insect fumigants. They may act on the insect respiratory system in their mode of action.

Tags: glucosinolate-breakdown, insect-fumigants, musca-domestica, nih, rhyzopertha-dominica
Organization: U.S. Department of Health & Human Services
Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!

Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the play of chance. Reliance on such analyses is likely to be more erroneous, and hence harmful, than application of the overall proportional (or relative) result in the whole trial to the estimate of absolute risk in that subgroup. Plausible explanations can usually be found for effects that are, in reality, simply due to the play of chance. When clinicians believe such subgroup analyses, there is a real danger of harm to the individual patient.

Tags: clinical-trials, nih, research-bias, statistical-power, subgroup-analysis
Organization: U.S. Department of Health & Human Services
National Survey of Substance Abuse Treatment Services (N-SSATS): 2005 Data on Substance Abuse Treatment Facilities

This report presents results from the 2005 National Survey of Substance Abuse Treatment Services (N-SSATS), an annual census of facilities providing substance abuse treatment. Conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), the N-SSATS is designed to collect data on the location, characteristics, and use of alcoholism and drug abuse treatment facilities and services throughout the 50 states, the District of Columbia, and other U.S. jurisdictions.

Tags: alcoholism-treatment, drug-abuse-treatment, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
2011-2012 NSDUH: Guide to State Tables and Summary of SAE Methodology

This document provides information on the model-based small area estimates of substance use and mental disorders in States based on data from the combined 2011-2012 National Surveys on Drug Use and Health (NSDUHs).

Tags: mental-disorders, samhsa, small-area-estimation, state-level-data, substance-use
Organization: U.S. Department of Health & Human Services
2018 Uniform Reporting System (URS) Table for Palau

This is the 2018 Uniform Reporting System (URS) Output Tables for Palau. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, palau-mental-health, samhsa
Organization: U.S. Department of Health & Human Services
The immunological effects of continuous veno-venous haemodiafiltration
		  in critically ill patients

Background:
          Haemodynamic instability is common in septic patients with acute
				renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore
				used as an alternative to conventional haemodialysis. Haemodialysis is
				associated with an activation of the immune system. The aim of the present
				study was to test the hypothesis that initiation of CVVHD influences the immune
				system with release of proinflammatory cytokines followed by a decrease in
				granulocyte activation, as assessed by the expression of adhesion
				molecules.
        
        
          Results:
          Fifteen patients were included. Mean Acute Physiology and Chronic
				Health Evaluation-2 score before CVVHD was 19 (range 8⌓27). Mean duration of
				CVVHD treatment was 9 days (1⌓21 days). Tumour necrosis factor-α and
				interleukin-8 were detectable in plasma in all patients, whereas interleukin-10
				was detectable only in a few patients. Proinflammatory and anti-inflammatory
				cytokines were detected in the ultrafiltrate. Large intraindividual and
				interindividual variations were demonstrated for all of the immunological
				parameters studied.
        
        
          Conclusion:
          The hypothesis that CVVHD induces the release of proinflammatory
				cytokines followed by a decrease in granulocyte activation was not confirmed in
				the present study. The heterogeneous group of patients studied, with different
				underlying diseases and various durations of illness before the start of CVVHD,
				might have contributed to the difficulty in demonstrating the proposed
				immunological effect of CVVHD.

Tags: cvvhd, cytokine-levels, immune-response, nih, septic-patients
Organization: U.S. Department of Health & Human Services
2016 Uniform Reporting System (URS) Table for New Mexico

This is the 2016 Uniform Reporting System (URS) Output Tables for New Mexico. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, new-mexico, samhsa
Organization: U.S. Department of Health & Human Services
2019 Uniform Reporting System (URS) Table for Illinois

These are the 2019 Uniform Reporting System (URS) Output Tables for Illinois. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, illinois-urs, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services
Compound 527236: 2,6,6-Trimethyltricyclo[6.2.1.01,5]undecane-7-carbaldehyde

Chemical compound data from PubChem database. IUPAC Name: 2,6,6-trimethyltricyclo[6.2.1.01,5]undecane-7-carbaldehyde. Molecular Formula: C15H24O. Molecular Weight: 220.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
NSDUH 2023 Screening Specifications

Browse the screening questionnaire used to determine respondent eligibility for the full 2023 National Survey on Drug Use and Health (NSDUH) interview. The documents include the exact questions as they appear in the screener, along with the skip patterns that determined whether a person was asked a question or not. There are two versions available – one for in-person screenings and another for web screenings. Both include English and Spanish language questions.

Tags: mental-health, nsduh-2023, samhsa, screening-questionnaire, substance-use
Organization: U.S. Department of Health & Human Services
Atlanta-Sandy Springs-Marietta, GA

This report presents combined 2005 to 2010 National Survey on Drug Use and Health (NSDUH) results for those aged 12 or older in the Atlanta-Sandy Springs-Marietta, Georgia metro area. The report includes estimates of substance use disorder, major depressive episode, illicit drug use, marijuana use, cigarette use, binge alcohol use, and the nonmedical use of prescription-type pain relievers. Results are provided for Atlanta-Sandy Springs-Marietta, Georgia, and the U.S. overall.

Tags: atlanta-metro, mental-health, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Risk and Protective Factors Tables (Prevalence Estimates) - 3.1 to 3.25

These detailed tables present totals and prevalence estimates of risk and protective factors regarding substance use from the 2011 National Survey on Drug Use and Health (NSDUH). The factors include perceptions of 1) risk of substance use, 2) availability of substances, 3) parental disapproval of youth substance use, 4) peer substance use. They also include measures of delinquent behavior, religious involvement, exposure to prevention messages, and parental involvement. Results are provided by age group, gender, race/ethnicity, geographic area, and youth substance use behavior. Comparisons are made between 2011 and 2010.

Tags: protective-factors, risk-factors, samhsa, substance-use, youth-behavior
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Kentucky, 2013

This is a behavioral health report for the state of Kentucky. It uses the  National Survey on Drug Use and Health (NSDUH) and the National Survey of Substance Abuse Treatment Services (NSSATS) to address the topics of youth substance use , youth mental health and treatment, adult mental health and treatment, substance use, substance use treatment for the years 2008 to 2012.

Tags: adult-mental-health, kentucky-behavioral-health, samhsa, substance-use-trends, youth-mental-health
Organization: U.S. Department of Health & Human Services
Behavioral Health Barometer: Delaware, 2015

This is a behavioral health report for the state of Delaware. The report utilizes data from the National Survey on Drug Use and Health (NSDUH), and the Uniform Reporting System. The topics addressed in the report include youth substance use, youth mental health and treatment, mental health and treatment, substance use and substance use treatment.

Tags: delaware-behavioral-health, mental-health-treatment, nsduh-data, samhsa, youth-substance-use
Organization: U.S. Department of Health & Human Services
Results From the National Child Welfare Information Study, 2020

This report presents results from a national research study, which was conducted by Child Welfare Information Gateway with funding from the Children’s Bureau, to better understand how child welfare professionals who work in state and local child welfare agencies, with tribes, and in courts access information and use technology to inform their practice.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, data, fiscal, policy, scope
Organization: U.S. Department of Health & Human Services
South Carolina (SC)

This report presents estimates for measures of substance use and mental health based on the combined 2010 and 2011 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for South Carolina for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh-data, samhsa, south-carolina, substance-use
Organization: U.S. Department of Health & Human Services
Debate: Should statin be used in patients with heart failure?

Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent etiology of heart failure is CAD, preventing CAD may prevent heart failure progression. Statins may have other beneficial effects besides cholesterol lowering, such as anti-inflammatory properties and improvement of endothelial function. On the contrary, high levels of cholesterol can be beneficial in heart failure patients on the basis of the ability of serum lipoproteins to modulate inflammatory response. Furthermore, statins affecting mitochondrial function can have a deleterious effect on skeletal or cardiac muscles. Despite all these conflicting data, there is no evidence from trials on the effects of statins in patients with heart failure. For this reason, the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI) investigators planned a controlled trial testing the effect of statins in patients with heart failure of different etiology.

Tags: cardiovascular-disease, clinical-trial, heart-failure, nih, statin-therapy
Organization: U.S. Department of Health & Human Services
Trends in the Use of Methadone, Buprenorphine, and Extended-release Naltrexone at Substance Abuse Treatment Facilities: 2003-2015 (Update)

Trends in the Use of Methadone, Buprenorphine, and Extended-release Naltrexone at Substance Abuse Treatment Facilities: 2003-2015 (Update)

Tags: medication-assisted-treatment, methadone-buprenorphine, opioid-use-disorder, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services