AndreaBozzo/ceres-open-data-index huggingface dataset:
Information Memorandum (IM-20-06)

This Information Memoranda (IM) provides information on best practices, resources, and recommendations for using foster care as a support for families in a way that mitigates the trauma of removal for the child and parents, expedites safe and successful reunification, and improves parent and child well-being outcomes. This Information Memorandum (IM) emphasizes the importance of state and tribal child welfare communities building and supporting relationships between resource families and parents to facilitate improved engagement of parents, promote timely reunification, build protective capacities in parents, and strengthen overall child and family well-being, while ensuring child safety.

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Tags: care, foster, guidance, policy, trauma
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-20-08)

This Information Memorandum (IM) encourages title IV-E agencies to make use of flexibilities and options within the title IV-E program to improve support for relatives and kin caring for children in foster care, in response to the Executive Order 13930, Strengthening the Child Welfare System for America’s Children.

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Tags: care, foster, guidance, kinship, policy
Organization: U.S. Department of Health & Human Services
Combating Kinetoplastid diseases

Today's Kinetoplastida form a diverse order of flagellated protozoans that have evolved from an ancient lineage, rooted near the base of the eukaryotic tree. The disease caused by some species of the Order Kinetoplastida have always plagued mankind, and today most are at least as prevalent as they have ever been. Kinetoplastid parasites cause disease in humans, animals and plants, severely affecting human health and retarding agriculture development in less developed countries. Sleeping sickness (caused by pathogenic subspecies ofTrypanosoma brucei), Chagas disease (caused byTrypanosoma cruzi) and the Leishmaniases (caused byLeishmania spp) are the major human diseases caused by kinetoplastids. According to the World Health Organization "sleeping sickness" affects more than 60 million men, women and children in 36 countries of sub-Saharan Africa, most of which are among the least developed countries in the world. In many of these countries sleeping sickness is currently epidemic, re-emerging in some as a greater cause of morbidity than evenHIV/AIDS.T. cruzicurrently infects 14 million people in Latin America. It is the agent ofChagas disease, the leading infectious cardiomyopathy in the world. Theleishmaniasesand the suffering they cause threaten 350 million women, men and children in 88 countries around the world, 72 of which are developing countries. In addition to their medical importance kinetoplastid parasites also cost developing nations millions of dollars in lost agricultural revenues, since other kinetoplastids are pestilences that strike agricultural produce from crops, to fish to cattle.

Tags: disease-control, kinetoplastid-diseases, nih, parasitic-diseases, tropical-diseases
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-18-12)

This Program Instruction (PI) provides State, Territorial, and Tribal title IV-E agencies (hereafter, "title IV-E agencies") with the revised form and instructions approved by the U.S. Office of Management and Budget (OMB) for reporting quarterly financial information on the title IV-E Foster Care, Adoption Assistance, and Guardianship Assistance, Kinship Navigator and Prevention Services Programs. This PI also provides continuing guidance for the submission of the Annual Adoption Savings Calculation and Accounting Report.

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Tags: adoption, fiscal, foster, prevention, reporting
Organization: U.S. Department of Health & Human Services
TheG-308Avariant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution

Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has been shown to induce insulin resistance, and a polymorphism at position -308 in the promoter region ofTNF-αhas been shown to increase transcription of the gene in adipocytes. Aim of this study is to investigate the role of theG-308A TNFαvariant in obesity and to study the possible influence of this mutation on body fat distribution and on measures of obesity (including Fat Free Mass, Fat Mass, basal metabolic rate), insulin resistance (measured as HOMAIR), and lipid abnormalities. TheG-308A TNFαpolymorphism has been studied in 115 patients with obesity (mean BMI 33.9 ± 0.5) and in 79 normal lean subjects (mean BMI 24.3 ± 0.3).

Tags: g-308a-polymorphism, insulin-resistance, nih, obesity-genetics, tnf-alpha
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-93-27)

This Information Memorandum (IM) informs the States of two final rules for the Adoption and Foster Care Analysis and Reporting System (AFCARS) and the Statewide Automated child Welfare Information System (SACWIS).

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Tags: adoption, foster, guidance, policy, reporting
Organization: U.S. Department of Health & Human Services
Quantitation ofPseudomonas aeruginosain wound biopsy samples: from bacterial culture to rapid `real-time' polymerase chain reaction

Early diagnosis of wound colonisation or prediction of wound sepsis provides an opportunity for therapeutic intervention. There is need for qualitative and quantitative tests that are more rapid than bacterial culture.Pseudomonas aeruginosaresults in high morbidity and mortality rates, is inherently resistant to common antibiotics, and is increasingly being isolated as a nosocomial pathogen. We developed three PCR-based methods to detect and quantifyP aeruginosain wound biopsy samples: conventional PCR, enzyme-linked immunosorbent assay (ELISA)-PCR, and RTD-PCR with rapid thermal cycling (LightCycler™technology), all based on the amplification of the outer membrane lipoprotein geneoprL. We compared the efficacy of these methods to bacterial culture by quantitatively measuring levels ofP aeruginosain serial dilutions, in reconstituted skin samples and 21 burn wound biopsy samples.

Tags: nih, pseudomonas-aeruginosa, rapid-detection, real-time-pcr, wound-infection
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-88-07)

This Program Instruction (PI) supersedes ACYF-PI-81-02, ACYF-PI-82-01, ACYF-PI-83-06, and ACYF-PI-85-01. This PI provides instruction on revised Title IV-E State Plans.

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Tags: child, guidance, instruction, policy, regulation
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-15-02)

This Information Memorandum (IM) emphasizes the importance of child welfare agencies assessing and providing appropriate services to families with a child in foster care or involved with a child welfare agency, whose parent(s) and legal guardians may be at risk of, or are, being detained or deported.

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Tags: care, child, foster, guidance, policy
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-81-02)

This Information Memorandum (IM) provides information on the computation of the state allotments for AFDC - foster care (FC) under title IV-E or IV-A for FY 81.

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Tags: data, foster, policy, scope, state
Organization: U.S. Department of Health & Human Services
Killing ofMycobacterium aviumsubspeciesparatuberculosiswithin macrophages

Mycobacterium aviumsubspeciesparatuberculosis(M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival ofM. paratuberculosisinfections within cultured macrophages to better understand the interplay between bacterium and host.

Tags: intracellular-pathogen, macrophage-infection, mycobacterium-avium, nih, paratuberculosis
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-17-02)

This Information Memorandum (IM) encourages all child welfare agencies, courts, administrative offices of the courts, and Court Improvement Programs to work together to ensure parents, children and youth, and child welfare agencies, receive high quality legal representation at all stages of child welfare proceedings.

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Tags: child, court, guidance, legal, policy
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-19-02)

This Information Memorandum informs title IV-E agencies that the Children’s Bureau published a NPRM to revise the AFCARS data elements in the Federal Register on April 19, 2019 (84 FR 16572
  
  

).

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Tags: child, data, policy, reporting, social
Organization: U.S. Department of Health & Human Services
Long termin-vivostudies of a photo-oxidized bovine osteochondral transplant in sheep

Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been made to find the ideal graft for larger cartilage lesions. Different grafts, such as untreated or cryopreserved osteochondral transplants, have been used with variable success.

Tags: articular-cartilage, nih, osteochondral-grafts, ovine-model
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-20-02)

This information memorandum provides information on research, best practices, resources and recommendations for providing children and youth in out-of-home care safe, meaningful and high frequency family time that strengthens the family, expedites reunification and improves parent and child well-being outcomes.

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Tags: care, guidance, out, policy, reunification
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-12-05)

This Program Instruction (PI) provides instruction to States on the June 30, 2012 submission of the Annual Progress and Services Report (APSR) required under Title IV-B of the Act for the Stephanie Tubbs Jones Child Welfare Services (CWS) and Promoting Safe and Stable Families (PSSF) Programs, the Child Abuse Prevention and Treatment Act (CAPTA) State Grant Program; and the Chafee Foster Care Independence Program (CFCIP) and the Education and Training Vouchers (ETV) Program; and the CFS-101, Part I, Annual Budget Request, Part II, Annual Summary of Child and Family Services, and Part III, Annual Expenditure Report—Title IV-B, subparts 1 and 2, CFCIP, and ETV.

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Tags: abuse, compliance, foster, grant, reporting
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-18-01)

This Program Instruction (PI) provides guidance to states, territories, and insular areas (hereafter “states,” unless otherwise noted) on actions they are required to take to receive their allotments for federal fiscal year (FY) 2019 (subject to the availability of appropriations) authorized under title IV-B, subparts 1 and 2, section 106 of CAPTA, CFCIP and ETV programs.

PI-18-01 (PDF)

States should use FY 2017 allocation tables as the basis for estimating FY 2019 budget requests.

Fiscal Year 2017 Allotment Title IV-B Subpart 1 Stephanie Tubbs Jones Child Welfare Services
Fiscal Year 2017 Allotment Title IV-B Subpart 2 Promoting Safe and Stable Families
Fiscal Year 2017 Allotment for Title IV-B, Subpart 2 Monthly Caseworker Visit Funds
Fiscal Year 2017 Allotment for CAPTA
Fiscal Year 2017 Allotment for Chafee Foster Care Independence Program
Fiscal Year 2017 Allotment for Education and Training Vouchers

CFS-101 Instructions, Part I, II, and III

Introduction
Part I: Annual Budget Request for Title IV-B, Subpart 1 & 2 Funds, CAPTA, CFCIP, and ETV Instructions
Part II: Annual Estimated Expenditure Summary of Child and Family Services Instructions
Part III: Expenditures for Title IV-B, Subparts 1 and 2, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Programs Instructions

CFS-101 Forms, Parts I, II  and III Excel Workbook (XLSX) (40 KB)

CFS-101 Forms Part I
CFS-101 Forms Part II
CFS-101 Forms Part III

CB Regional Program Managers

NCANDS State Contact List

Annual Reporting of Education and Training Vouchers Awarded (PDF (PDF) - 101 KB)

The PDF is best viewed in Chrome or Firefox. If using Internet Explorer (IE), please right click the link, save the file, and view it locally.

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Tags: child, fiscal, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Response ofEscherichia colicontaining mycobacterial carotene genes to UV radiation

Carotenoid pigments are largely distributed in nature. They are
present in all of the photosynthetic organisms as well as in some bacteria, fungi, and yeast [1]. Two major biological roles have been assigned to carotenoids in plants and prokaryotes. In photosynthetic organisms, these pigments are involved in trapping light energy. A more general role applicable to both photosynthetic and non-photosynthetic cell, is protection from photodynamic action [1]. Genes controlling the synthesis of these pigments have been studied in several organisms such asErwiniaspecies [2,3,4],Mycobacterium aurumA+[5,6],Arabidopsis[7,8],Xantophyllomyces dendrorhous[9] andBrevibacterium linens[10].

Tags: lycopene-biogenesis, mycobacterium-aurum, neurosporene-synthesis, nih, ultraviolet-resistance
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-07-04)

This Program Instruction (PI) provides instruction on Assisted Guardianship Child Welfare Waiver Demonstration Projects and Categorical Eligibility for Medicaid for Title IV-E Eligible Children.

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Tags: guidance, instruction, medicaid, policy, regulation
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-98-03)

This Information Memorandum (IM) provides information on implementation of Federal legislation- Questions and answers that clarify the practice and implementation of section 471(a)(18) of title IV-E of the Social Security Act.

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Tags: child, federal, guidance, policy, social
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-01-08)

This Information Memorandum (IM) announces an amendment to Title IV-E Adoption Assistance for Children who are Voluntarily Relinquished to Private, Nonprofit Agencies (Amends Policy on Children who are Voluntarily Relinquished to a Private, Nonprofit Agency set forth in ACYF-CB-PA-01-01).

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Tags: adoption, child, grant, policy, social
Organization: U.S. Department of Health & Human Services
Correction

This year marks the 100th anniversary of the discovery by Camillo Golgi of an “internal reticular apparatus” in eukaryotic cells. The cover figure, from a classic paper by Friend and Murray (Friend, D.S., and Murray, M.J. [1965]. Am. J. Anat.117, 135–150), highlights the pivotal role played by electron microscopy in developing the modern view of the Golgi apparatus. In the earlier phase of Golgi research, this organelle has been visualized by light microscopy, often using osmium as a specific stain. For example, the inset of the figure is a light micrograph showing mouse epithelial cells that were stained with osmium and then sectioned parallel to their long axis. The Golgi apparatus appears as a reticulum above the nucleus. The remainder of the figure shows the same preparation of osmicated cells, except in this case they were sectioned perpendicular to their long axis and viewed by electron microscopy. Such images revealed that the Golgi reticulum comprises multiple interconnected stacks of membrane cisternae. Remarkably, Friend and Murray found that osmium selectively stains the cisternae on one side of each Golgi stack. This result provided some of the first concrete evidence that the Golgi apparatus is biochemically polarized. Today, a third of a century later, cell biologists are still striving to understand the mechanisms that generate polarized Golgi stacks.—Benjamin Glick

Tags: data-correction, nih, publication-bias, research-misconduct, scientific-integrity
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-15-10)

This Program Instruction (PI) provides an update to Indian tribes, tribal organizations, and tribal consortia (tribes) of the basis upon which the allotment authorized under title IV-B, subparts 1 and/or 2 will be made beginning with fiscal year (FY) 2016 awards, including instructions allowing tribes to self-certify their own population counts.

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Tags: child, fiscal, instruction, policy, tribal
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-93-22)

This Information Memorandum (IM) provides information on the Reauthorization of the Federal Independent Living Program (ILP) - Availability of Fiscal Year 1993 Funds for the ILP.

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Tags: fiscal, funding, policy, program, social
Organization: U.S. Department of Health & Human Services
Action Transmittal (AT-OSSP-00-01)

This Action Transmittal (AT) establishes procedures and new criteria by which the Department of Health and Human Services (DHHS) will, on a limited exception basis, consider approving Federal financial participation (FFP) in State automatic data processing (ADP) equipment and services acquisitions, when a State has failed to obtain DHHS' prior written approval in accordance with the requirements of 45 CFR Part 95, Subpart F.

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Tags: compliance, data, guidance, policy, scope
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-16-03)

This Program Instruction (PI) provides guidance to states, territories, and insular areas (hereafter “states,” unless otherwise noted) on actions they are required to take to receive their allotments for federal fiscal year (FY) 2017 (subject to the availability of appropriations) authorized under title IV-B, subparts 1 and 2, section 106 of CAPTA, CFCIP and ETV programs.

PI-16-03 (PDF)

Fiscal Year 2016 Allotment Title IV-B Subpart 1 Stephanie Tubbs Jones Child Welfare Services
Fiscal Year 2016 Allotment Title IV-B Subpart 2 Promoting Safe and Stable Families
Fiscal Year 2016 Allotment for Title IV-B, Subpart 2 Monthly Caseworker Visit Funds
Fiscal Year 2016 Allotment for CAPTA
Fiscal Year 2016 Allotment for Chafee Foster Care Independence Program
Fiscal Year 2016 Allotment for Education and Training Vouchers

CFS-101 Part I:  Annual Budget Request for Title IV-B, subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Program Instructions
CFS-101 Part I:  Annual Budget Request for Title IV-B, subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Program Form (Excel (XLSX) - 13 KB)
CFS-101, Part II:  Annual Summary of Child and Family Services Instructions
CFS-101, Part II:  Annual Summary of Child and Family Services Form (Excel (XLSX) - 13 KB)
CFS-101, Part III:  Annual Expenditures for Title IV-B, subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Instructions
CFS-101, Part III:  Annual Expenditures for Title IV-B, subparts 1 and 2, CAPTA, Chafee Foster Care Independence (CFCIP) and Education and Training Voucher (ETV) Form (Excel (XLSX) - 12 KB)

CB Regional Program Managers

NCANDS State Contact List

Annual Reporting of Education and Training Vouchers Awarded (Word (DOCX) - 22 KB)

CAPTA State Plan Assurances (Word (DOCX) - 24 KB)

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Tags: child, fiscal, guidance, instruction, policy
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-95-12)

This Information Memorandum (IM) provides information on the possible limitation on amount of allowable child placement services, administrative expenditures and training costs reimbursable under title IV-E in and for Federal Fiscal Year (FY) 1995.

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Tags: child, fiscal, guidance, policy, regulation
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-06-04)

This Program Instruction (PI) provides instruction to tribes on the June 30, 2006 submission of the Annual Progress and Services Report (APSR) as required under Title IV-B of the Social Security Act, including the submission of the CFS-101, Parts I and II, Annual Budget Request and Annual Summary of Child and Family Services.

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Tags: child, compliance, instruction, policy, reporting
Organization: U.S. Department of Health & Human Services
Information Memorandum (IM-84-09)

This Information Memorandum (IM) establishes FY 1984 allotments for title IV-B, and procedures for applying for: (1) A state's share of funds available under title IV-B in FY 1984; (2) reallotted IV-B funds; and (3) Funds to be transferred from title IV-E-foster care.

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Tags: child, foster, guidance, policy, scope
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-05-03)

Availability of Fiscal Year (FY) 2005 Funds under the Community-Based Grants for the Prevention of Child Abuse and Neglect program created by title II of the Child Abuse Prevention and Treatment Act as amended by Pub. L. 108-36.

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Tags: abuse, fiscal, grant, neglect, prevention
Organization: U.S. Department of Health & Human Services
Program Instruction (PI-08-01)

This Program Instruction (PI) provides instruction on the availability of Fiscal Year (FY) 2008 Funds under the Community-Based Grants for the Prevention of Child Abuse and Neglect program created by title II of the Child Abuse Prevention and Treatment Act as amended by P.L. 108-36.

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Tags: abuse, fiscal, grant, neglect, prevention
Organization: U.S. Department of Health & Human Services
Growth ofHelicobacter pyloriin a long spiral form does not alter expression of immunodominant proteins

We have previously reported that altered culture conditions (a broth media with shaking) could induce a strain ofHelicobacter pylorito assume a long spiral morphology resembling that described forHelicobacter heilmannii. The present study was initiated to determine if other strains ofH. pyloricould be induced to assume that morphology and if doing so would alter the expression of immunodominant proteins.

Tags: bacterial-morphology, helicobacter-pylori, immunodominant-proteins, nih, urease-gene
Organization: U.S. Department of Health & Human Services