AndreaBozzo/ceres-open-data-index huggingface dataset:
2014 CMHS Uniform Reporting System (URS) Table for Connecticut

2014 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Connecticut. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, connecticut, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region:

Background:
          Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery, characterization, and genomic context of a novel human NBC-like gene, SLC4A9, on chromosome 5q31.
        
        
          Results:
          SLC4A9 was initially discovered by genomic sequence annotation and further characterized by sequencing of long-insert cDNA library clones. The predicted protein of 990 amino acids has 12 transmembrane domains and high sequence similarity to other NBCs. The 23-exon gene has 14 known mRNA isoforms. In three regions, mRNA sequence variation is generated by the inclusion or exclusion of portions of an exon. Noncoding SLC4A9 cDNAs were recovered multiple times from different libraries. The 3' untranslated region is fragmented into six alternatively spliced exons and contains expressed Alu, LINE and MER repeats. SLC4A9 has two alternative stop codons and six polyadenylation sites. Its expression is largely restricted to the kidney. In silico approaches were used to characterize two additional novel SLC4A genes and to place SLC4A9 within the context of multiple paralogous gene clusters containing members of the epidermal growth factor (EGF), ankyrin (ANK) and fibroblast growth factor (FGF) families. Seven human EGF-SLC4A-ANK-FGF clusters were found.
        
        
          Conclusion:
          The novel sodium bicarbonate cotransporter-like gene SLC4A9 demonstrates abundant alternative mRNA processing. It belongs to a growing class of functionally diverse genes characterized by inefficient highly variable splicing. The evolutionary history of the EGF-SLC4A-ANK-FGF gene clusters involves multiple rounds of duplication, apparently followed by large insertions and deletions at paralogous loci and genome-wide gene shuffling.

Tags: gene-expression, ion-transport, membrane-proteins, nih, sodium-bicarbonate
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Arizona

This is the 2021 Uniform Reporting System (URS) Output Tables for Arizona. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: arizona-mental-health, mental-health-services, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Penis size: Survey of female perceptions of sexual satisfaction

Background
          Does the size of the male penis, in terms of length or width, make a difference in female sexual satisfaction?
        
        
          Method
          To study the effect of penis width vs. length on female sexual satisfaction, 50 sexually active female undergraduate students were asked which felt better, i. e., was penis width or length more important for their sexual satisfaction.
        
        
          Results
          None reported they did not know, or that width and length were equally satisfying. A large majority, 45 of 50, reported width was more important (p < .001).
        
        
          Conclusion
          Implications are discussed, including the fact that the data seem to contradict Masters and Johnson about penis size having no physiological effect on female sexual satisfaction.

Tags: female-perception, nih, penis-size, sexual-health, sexual-satisfaction
Organization: U.S. Department of Health & Human Services
2010 CMHS Uniform Reporting System (URS) Output Tables for South Carolina

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2010. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, south-carolina
Organization: U.S. Department of Health & Human Services
Compound 528535: Hexadecane, 7-decyl

Chemical compound data from PubChem database. IUPAC Name: 10-hexylicosane. Molecular Formula: C26H54. Molecular Weight: 366.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Beneficial effect of carboxy-PTIO on hemodynamic and blood gas changes in septic shock dogs

Background:
          Nitric oxide (NO) production following bacterial infection may play a physiological role in the host defense mechanism due to its antimicrobial activity. However, excess production of NO in severe infection such as sepsis has been implicated in the pathogenesis of septic shock. To determine whether a nitronyl nitroxide NO scavenger compound could prevent the hemodynamic and blood gas alterations in sepsis, bacterial lipopolysaccharide (LPS: 250ng/kg/min) was administered for 2 h in anesthetized dogs with or without infusion of carboxy-2-phenyl-4, 4, 5, 5-tetramethylimidazoline-1-oxyl-3-oxide (carboxy-PTIO: 0.1 mg/kg/min) for 1 h. Control animals received isotonic saline instead of LPS with or without carboxy-PTIO.
        
        
          Results:
          Infusion of LPS caused a marked decrease in mean arterial pressure (MAP), metabolic acidosis, and hypoxia. These effects were reversed by co-administration of carboxy-PTIO, without affecting other hemodynamic parameters. In control animals, neither hemodynamic nor blood gas parameters changed with or without carboxy-PTIO.
        
        
          Conclusion:
          These results indicate that carboxy-PTIO attenuates LPS-induced hypotension, metabolic acidosis, and hypoxia by scavenging excess NO from the circulation without affecting NO synthase (NOS) activity. An NO scavenger, carboxy-PTIO, may be preferable to non-selective NOS inhibitors for the treatment of human septic shock.

Tags: carboxy-ptio, hemodynamic-response, nih, nitric-oxide, septic-shock
Organization: U.S. Department of Health & Human Services
Evidence for an evolutionarily conserved interaction between cell wall biosynthesis and flowering in maize and sorghum

Background
          Factors that affect flowering vary among different plant species, and in the grasses in particular the exact mechanism behind this transition is not fully understood. The brown midrib (bm) mutants of maize (Zea mays L.), which have altered cell wall composition, have different flowering dynamics compared to their wild-type counterparts. This is indicative of a link between cell wall biogenesis and flowering. In order to test whether this relationship also exists in other grasses, the flowering dynamics in sorghum (Sorghum bicolor (L.) Moench) were investigated. Sorghum is evolutionarily closely related to maize, and a set of brown midrib (bmr) mutants similar to the maize bm mutants is available, making sorghum a suitable choice for study in this context.
        
        
          Results
          We compared the flowering time (time to half-bloom) of several different bmr sorghum lines and their wild-type counterparts. This revealed that the relationship between cell wall composition and flowering was conserved in sorghum. Specifically, the mutant bmr7 flowered significantly earlier than the corresponding wild-type control, whereas the mutants bmr2, bmr4, bmr6, bmr12, and bmr19 flowered later than their wild-type controls.
        
        
          Conclusion
          The change in flowering dynamics in several of the brown midrib sorghum lines provides evidence for an evolutionarily conserved mechanism that links cell wall biosynthesis to flowering dynamics. The availability of the sorghum bmr mutants expands the germplasm available to investigate this relationship in further detail.

Tags: brown-midrib-mutants, cell-wall-biosynthesis, maize-sorghum, nih, plant-flowering-time
Organization: U.S. Department of Health & Human Services
New York (NY)

This report presents New York\'s estimates for 25 measures of substance use and mental health based on the combined 2009 and 2010 National Surveys on Drug Use and Health (NSDUHs). Topics covered include past month substance use (e.g., illicit drugs, marijuana, cocaine, pain relievers, alcohol, tobacco), substance dependence, abuse, and treatment need, past year serious mental illness (SMI), any mental illness (AMI), suicidal thoughts, and major depressive episode (MDE). Resuts are provided for New York for five age groups: 12 to 17, 18 to 25, 26 or older, 18 or older and all persons 12 or older.

Tags: mental-health, nsduh-survey, ny-behavioral-health, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Compound 528538: Hexadecane, 7-nonyl

Chemical compound data from PubChem database. IUPAC Name: 10-hexylnonadecane. Molecular Formula: C25H52. Molecular Weight: 352.7. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2011 CMHS Uniform Reporting System (URS) Output Tables for Alaska

Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for 2011. The Uniform Reporting System (URS) is a state and national reporting system collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, community-mental-health, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Report to Congress on the National Incidence Study of Child Abuse and Neglect, Supplementary Analysis

This report provides an overview of the purpose of the supplementary analysis as well as a summary of key findings. In the supplementary analysis, data from the NIS-4 and the National Child Abuse and Neglect Data System (NCANDS) were used to examine the comparability of information reported by the two studies on children investigated by Child Protective Services (CPS), including data on the number of children investigated, the dispositional outcome of investigation, the types of maltreatment experienced by children, and the children’s age, sex, and race/ethnicity.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, maltreatment, neglect, policy, reporting
Organization: U.S. Department of Health & Human Services
Promoting Safe and Stable Families (PSSF) Program

The discretionary fund activities funded by the Promoting Safe and Stable Families (PSSF) Program are meant to develop a coordinated and integrated service system that builds on the strengths of families and communities; emphasize collaborative approaches, early identification of issues and the delivery of prevention, intervention and support services; prevent child abuse and neglect, protect children from further abuse, and promote permanency for children within their own families or with kinship or adoptive families; and strengthen families and remove barriers to child safety, permanency and well-being.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: abuse, intervention, neglect, policy, prevention
Organization: U.S. Department of Health & Human Services
Compound 527286: Citronellyl octanoate

Chemical compound data from PubChem database. IUPAC Name: 3,7-dimethyloct-6-enyl octanoate. Molecular Formula: C18H34O2. Molecular Weight: 282.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
The NSDUH Report: Need for and Receipt of Substance Use Treatment among Asian Americans and Pacific Islanders

This report uses 2003 to 2011 National Survey on Drug Use and Health (NSDUH) to assess past year need for and receipt of alcohol use treatment and illicit drug use treatment among Asian Americans and Pacific Islanders aged 12 or older in comparison to persons of other racial and ethnic groups. Results are shown by age group, gender, federal poverty level and health insurance coverage status.

Tags: asian-americans, pacific-islanders, samhsa, substance-use-treatment, treatment-gap
Organization: U.S. Department of Health & Human Services
Sample Size and Population Estimates Tables (Standard Errors and P Values) - 8.1 to 8.13

These detailed tables show standard errors for sample sizes and population estimates from the 2010 National Survey on Drug Use and Health (NSDUH). Standard errors for samples sizes and population estimates are provided by age group, gender, race/ethnicity, education level, employment status, geographic area, pregnancy status, college enrollment status, and probation/parole status.

Tags: nsduh-2010, population-estimates, samhsa, standard-errors, substance-use
Organization: U.S. Department of Health & Human Services
Systematic reviews of complementary therapies - an annotated bibliography. Part 1: Acupuncture

Background
          Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three major complementary therapies (acupuncture, herbal medicine, homeopathy). This article is dealing with acupuncture. Potentially relevant reviews were searched through the register of the Cochrane Complementary Medicine Field, the Cochrane Library, Medline, and bibliographies of articles and books. To be included articles had to review prospective clinical trials of acupuncture; had to describe review methods explicitly; had to be published; and had to focus on treatment effects. Information on conditions, interventions, methods, results and conclusions was extracted using a pretested form and summarized descriptively.
        
        
          Results
          From a total of 48 potentially relevant reviews preselected in a screeening process 39 met the inclusion criteria. 22 were on various pain syndromes or rheumatic diseases. Other topics addressed by more than one review were addiction, nausea, asthma and tinnitus. Almost unanimously the reviews state that acupuncture trials include too few patients. Often included trials are heterogeneous regarding patients, interventions and outcome measures, are considered to have insufficient quality and contradictory results. Convincing evidence is available only for postoperative nausea, for which acupuncture appears to be of benefit, and smoking cessation, where acupuncture is no more effective than sham acupuncture.
        
        
          Conclusions
          A large number of systematic reviews on acupuncture exists. What is most obvious from these reviews is the need for (the funding of) well-designed, larger clinical trials.

Tags: acupuncture-therapy, complementary-medicine, nih, pain-management, systematic-review
Organization: U.S. Department of Health & Human Services
2016 Uniform Reporting System (URS) Table for New Hampshire

This is the 2016 Uniform Reporting System (URS) Output Tables for New Hampshire. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Compound 525498: 5-Tert-butyl-2-ethylthiofuran

Chemical compound data from PubChem database. IUPAC Name: 2-tert-butyl-5-ethylsulfanylfuran. Molecular Formula: C10H16OS. Molecular Weight: 184.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for District of Columbia

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for District of Columbia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: community-mental-health, mental-health-services, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Miami - Dade Div: Drug-Related Emergency Department Visits, 2004-2011 - Underage Drinking

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving underage drinking in Dade division of the Miami metropolitan area, covering 2004-2011.  Underage drinking includes ED visits that involve alcohol use (alone or with other drugs) for patients under the age of 21.

Tags: alcohol-related-visits, emergency-department, miami-dade-county, samhsa, underage-drinking
Organization: U.S. Department of Health & Human Services
2021-2023 Companion Report on Race/Ethnicity

Review this high-level visual representation of key outcomes by race and ethnicity from the combined 2021-2023 National Surveys on Drug Use and Health (NSDUH). This infographic, accompanying the2023 NSDUH National Report, covers substance use, substance use disorders, mental health issues, suicidality, and perceived recovery from substance use problems or mental health issues among the noninstitutionalized population aged 12 or older in the United States.

Tags: mental-health, nsduh-data, racial-ethnic-disparities, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
California Presentation on Strategies for Reducing Long-Term Foster Care Population

The state of California has two Permanency Innovation Initiative (PII) grantees; they operate the California Partners for Permanency (CAPP)  and Recognize. Intervene. Support. Empower (RISE) projects. These presentation provides an overview of their strategies to reduce the number of children and youth in long-term foster care.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: foster, grant, intervention, permanency, policy
Organization: U.S. Department of Health & Human Services
Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants

Background
          Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with major economical impact and complex genomes. In this paper we exploit the recently described CODEHOP primer design and PCR strategy for targeted isolation of homologues in large gene families.
        
        
          Results
          The method was tested with two different objectives. The first was to analyze the evolution of the CYP98 family of cytochrome P450 genes involved in 3-hydroxylation of phenolic compounds and lignification in a broad range of plant species. The second was to isolate an orthologue of the sorghum glucosyl transferase UGT85B1 and to determine the complexity of the UGT85 family in wheat. P450s of the CYP98 family or closely related sequences were found in all vascular plants. No related sequence was found in moss. Neither extensive duplication of the CYP98 genes nor an orthologue of UGT85B1 were found in wheat. The UGT85A subfamily was however found to be highly variable in wheat.
        
        
          Conclusions
          Our data are in agreement with the implication of CYP98s in lignification and the evolution of 3-hydroxylation of lignin precursors with vascular plants. High conservation of the CYP98 family strongly argues in favour of an essential function in plant development. Conversely, high duplication and diversification of the UGT85A gene family in wheat suggests its involvement in adaptative response and provides a valuable pool of genes for biotechnological applications. This work demonstrates the high potential of the CODEHOP strategy for the exploration of large gene families in plants.

Tags: cytochrome-p450, gene-evolution, gene-families, nih, plant-genes
Organization: U.S. Department of Health & Human Services
Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery

Background
          Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these species may be implicated in certain pathophysiological events. We studied the possible role of low molecular mass dinitrosyl iron complexes in the control of noradrenaline release in electrically stimulated rat tail artery.
        
        
          Results
          A model complex, dinitrosyl-iron-thiosulfate (at 1–10 μM) produced a concentration-dependent enhancement of electrical field stimulated [3H]noradrenaline release (up to 2 fold). At the same time, dinitrosyl-iron-thiosulfate inhibited neurogenic vasoconstriction, consistent with its nitric oxide donor properties. A specific inhibitor of cyclic GMP dependent protein kinase, Rp-8pCPT-cGMPS, partially inhibited the effect of dinitrosyl-iron-thiosulfate on neurogenic vasoconstriction, but not on [3H]noradrenaline release. Another model complex, dinitrosyl-iron-cysteine (at 3 μM) elicited similar responses as dinitrosyl-iron-thiosulfate. Conventional NO and NO+ donors such as sodium nitroprusside, S-nitroso-L-cysteine or S-nitroso-glutathione (at 10 μM) had no effect on [3H]noradrenaline release, though they potently decreased electrically-induced vasoconstriction. The "false complex", iron(II)-thiosulfate showed no activity.
        
        
          Conclusions
          Low molecular mass iron dinitrosyl complexes can up-regulate the stimulation-evoked release of vascular [3H]noradrenaline, apparently independently of their NO donor properties. This finding may have important implications in inflammatory tissues.

Tags: dinitrosyl-iron-complexes, neurogenic-vasoconstriction, nih, noradrenaline-release, rat-tail-artery
Organization: U.S. Department of Health & Human Services