AndreaBozzo/ceres-open-data-index huggingface dataset:
Twisted fallopian tube in pregnancy: a case report

Background
          Isolated twisted fallopian tube is an uncommon event, isolated twisted fallopian tube in pregnancy is also very rare. The diagnosis is often difficult and established during the operation. The right fallopian tube is most common affected.
        
        
          Case presentation
          We report an uncommon twisted left fallopian tube in pregnancy. A 34-year-old G3P2 28 weeks pregnant woman presented with acute left lower abdominal pain. The clinical and ultrasonographic findings led to diagnosis of twisted left ovarian cyst. Emergency exploratory laparotomy was performed. A twisted left fallopian tube and paratubal cyst was noted and left salpingectomy was performed. The postoperative course was uneventful and the pregnancy continued until term without complication.
        
        
          Conclusions
          Although isolated twisted fallopian tube during pregnancy is very rare, it should be included in the differential diagnosis of acute abdomen in pregnancy. Early surgical intervention will decrease obstetric morbidity and may allow preservation of the fallopian tube.

Tags: case-report, fallopian-tube-torsion, nih, pregnancy-complications, salpingectomy
Organization: U.S. Department of Health & Human Services
Compound 527303: 8a-methyl-4-methylidene-6-propan-2-yl-3,4a,5,6,7,8-hexahydro-2H-naphthalen-1-one

Chemical compound data from PubChem database. IUPAC Name: 8a-methyl-4-methylidene-6-propan-2-yl-3,4a,5,6,7,8-hexahydro-2H-naphthalen-1-one. Molecular Formula: C15H24O. Molecular Weight: 220.35. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Patent AT-E400670-T1: [Translated] DEVICE AND METHOD FOR COOLING TAPE-SHAPED SUBSTRATES

The invention relates to a device and a method for cooling strip substrates in vacuo, whereby a substrate (1) is run such as to wrap around a convex cooling surface, at least partly in a contact region (3) and a gap (10) is formed between the substrate (1) and the cooling surface in the contact region (3), whereby, in at least one first region (11) of the gap (10), a fluid is introduced through the cooling surface and said fluid is at least partly drained through the cooling surface from at least one second region (12; 13) of the gap (10).

Tags: chemistry, innovation, patent, pubchem, research
Organization: U.S. Department of Health & Human Services
Compound 525066: (10,13-dimethyl-6,7,8,9,11,12,14,15-octahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy-trimethylsilane

Chemical compound data from PubChem database. IUPAC Name: (10,13-dimethyl-6,7,8,9,11,12,14,15-octahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy-trimethylsilane. Molecular Formula: C22H34OSi. Molecular Weight: 342.6. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2023 Uniform Reporting System (URS) Table For North Carolina

This is the 2023 Uniform Reporting System (URS) Output Tables for North Carolina. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, evidence-based-practices, mental-health-services, noms-measures, samhsa
Organization: U.S. Department of Health & Human Services
Table 20. Illicit Drug Dependence in the Past Year among Persons Aged 12 or Older, by State and Substate Regions: Percentages, Annual Averages Based on 2008, 2009, and 2010 NSDUHs

This table presents the 2008 to 2010 National Survey on Drug Use and Health (NSDUH) estimates of past year illicit drug dependence by those aged 12 or older by State and substate regions.

Tags: adolescent-drug-use, illicit-drug-dependence, nsduh-data, samhsa, substance-use-disorder
Organization: U.S. Department of Health & Human Services
Mining microarray expression data by literature profiling

The lack of efficient techniques for assessing the biological implications of microarray gene-expression data remains an important obstacle in exploiting this information. To address this need, a mining technique has been developed based on the analysis of literature profiles generated by extracting the frequencies of certain terms from thousands of abstracts stored in the Medline literature database.

Tags: gene-expression, literature-mining, medline-abstracts, microarray-data, nih
Organization: U.S. Department of Health & Human Services
How hyperglycemia promotes atherosclerosis: molecular mechanisms

Both type I and type II diabetes are powerful and independent risk factors for coronary artery disease (CAD), stroke, and peripheral arterial disease. Atherosclerosis accounts for virtually 80% of all deaths among diabetic patients. Prolonged exposure to hyperglycemia is now recognized a major factor in the pathogenesis of atherosclerosis in diabetes. Hyperglycemia induces a large number of alterations at the cellular level of vascular tissue that potentially accelerate the atherosclerotic process. Animal and human studies have elucidated three major mechanisms that encompass most of the pathological alterations observed in the diabetic vasculature: 1) Nonenzymatic glycosylation of proteins and lipids which can interfere with their normal function by disrupting molecular conformation, alter enzymatic activity, reduce degradative capacity, and interfere with receptor recognition. In addition, glycosylated proteins interact with a specific receptor present on all cells relevant to the atherosclerotic process, including monocyte-derived macrophages, endothelial cells, and smooth muscle cells. The interaction of glycosylated proteins with their receptor results in the induction of oxidative stress and proinflammatory responses 2) oxidative stress 3) protein kinase C (PKC) activation with subsequent alteration in growth factor expression. Importantly, these mechanisms may be interrelated. For example, hyperglycemia-induced oxidative stress promotes both the formation of advanced glycosylation end products and PKC activation.

Tags: atherosclerosis, diabetes-complications, hyperglycemia, nih, vascular-disease
Organization: U.S. Department of Health & Human Services
Youth Mental Health Tables (Prevalence Estimates) - 2.1 to 2.14

These are the detailed tables pertaining to adult mental health from the 2010 National Survey on Drug Use and Health (NSDUH). These detailed tables present totals and prevalence estimates for youths include major depressive episode (MDE), treatment for depression (among youths with MDE), mental health service utilization, and measures related to the co-occurrence of mental disorders with substance use or with substance use disorders. Results are provided for age group, gender, race/ethnicity, education level, government assistance status, poverty level, geographic area, insurance status. Comparisons are made between 2010 and 2002 to 2009.

Tags: major-depressive-episode, mental-health-services, samhsa, substance-use-disorders, youth-mental-health
Organization: U.S. Department of Health & Human Services
Determination of PCR efficiency in chelex-100 purified clinical samples and comparison of real-time quantitative PCR and conventional PCR for detection of

Background
          Chlamydia pneumoniae infection has been detected by serological methods, but PCR is gaining more interest. A number of different PCR assays have been developed and some are used in combination with serology for diagnosis. Real-time PCR could be an attractive new PCR method; therefore it must be evaluated and compared to conventional PCR methods.
        
        
          Results
          We compared the performance of a newly developed real-time PCR with a conventional PCR method for detection of C. pneumoniae. The PCR methods were tested on reference samples containing C. pneumoniae DNA and on 136 nasopharyngeal samples from patients with a chronic cough. We found the same detection limit for the two methods and that clinical performance was equal for the real-time PCR and for the conventional PCR method, although only three samples tested positive. To investigate whether the low prevalence of C. pneumoniae among patients with a chronic cough was caused by suboptimal PCR efficiency in the samples, PCR efficiency was determined based on the real-time PCR. Seventeen of twenty randomly selected clinical samples had a similar PCR efficiency to samples containing pure genomic C. pneumoniae DNA.
        
        
          Conclusions
          These results indicate that the performance of real-time PCR is comparable to that of conventional PCR, but that needs to be confirmed further. Real-time PCR can be used to investigate the PCR efficiency which gives a rough estimate of how well the real-time PCR assay works in a specific sample type. Suboptimal PCR efficiency of PCR is not a likely explanation for the low positivity rate of C. pneumoniae in patients with a chronic cough.

Tags: chlamydia-pneumoniae, conventional-pcr, nasopharyngeal-samples, nih, real-time-pcr
Organization: U.S. Department of Health & Human Services
NSDUH 2020 Sample Design Report

Learn about the sample design used for the 2020 National Survey on Drug Use and Health (NSDUH). The report describes the five stages of sample selection, sample weighting and variance estimation procedures, and the impact of the coronavirus disease 2019 (COVID-19) pandemic on sampling.Chapters:Introduces the report, describes the target population, provides a general overview of the 2020 NSDUH sample design, and summarizes the impact of the COVID-19 pandemic on the 2020 NSDUH.Summarizes the 2014 through 2022 coordinated sample design.Discusses the first three stages of sample selection in greater detail.Discusses the fourth and fifth stages of sample selection.Describes sample weighting and variance estimation procedures for 2020.Describes the Clinical Validation Study that was conducted in 2020.

Tags: nsduh-sample-design, samhsa, sample-weighting, substance-use-survey, survey-methodology
Organization: U.S. Department of Health & Human Services
Nitric oxide: a pro-inflammatory mediator in lung disease?

Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is known to have anti-microbial, anti-inflammatory and anti-oxidant properties, various lines of evidence support the contribution of NO• to lung injury in several disease models. On the basis of biochemical evidence, it is often presumed that such NO• -dependent oxidations are due to the formation of the oxidant peroxynitrite, although alternative mechanisms involving the phagocyte-derived heme proteins myeloperoxidase and eosinophil peroxidase might be operative during conditions of inflammation. Because of the overwhelming literature on NO• generation and activities in the respiratory tract, it would be beyond the scope of this commentary to review this area comprehensively. Instead, it focuses on recent evidence and concepts of the presumed contribution of NO• to inflammatory diseases of the lung.

Tags: lung-inflammation, nih, nitric-oxide, oxidative-stress, respiratory-disease
Organization: U.S. Department of Health & Human Services
4.18b Types of client payments accepted by facility, by facility operation and primary focus of facility: 2011. Percent

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing types of client payments accepted by facility, by facility operation and primary focus of facility in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: facility-characteristics, n-ssats, payment-methods, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
Postponement of Title IV-E Foster Care Eligibility Reviews and National Youth in Transition Database Reviews

This letter to child welfare leaders announces an updated postponement of the Title IV-E Foster Care Eligibility Reviews and National Youth in Transition Database Reviews due to the COVID-19 pandemic. This letter extends the postponement announced in the March 18, 2020, letter.

Browse All COVID-19 Resources

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: 19, care, foster, policy, reporting
Organization: U.S. Department of Health & Human Services
2015 CMHS Uniform Reporting System (URS) Table for Illinois

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Illinois. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: illinois-mental-health, mental-health-services, noms-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
2010 State Profile — Washington

This state profile includes data from facilities in Washington that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Washington. In Washington, 455 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 41,522 clients in substance abuse treatment on March 31, 2010. The survey response rate in Washington was 96.4%.

Tags: n-ssats, samhsa, substance-abuse-treatment, treatment-facilities, washington-state
Organization: U.S. Department of Health & Human Services
Treatment Episode Data Set (TEDS) 2000-2010 National Admissions to Substance Abuse Treatment Services

This is the Treatment Episode Data Set (TEDS) National Admissions to Substance Abuse Treatment Services report for 2000-2010. This report provides information on the demographic and substance abuse characteristics of admissions to treatment aged 12 and older for abuse of alcohol and/or drugs in facilities that report to individual State administrative data systems.

Tags: alcohol-drug-abuse, samhsa, substance-abuse-treatment, teds-admissions, treatment-episodes
Organization: U.S. Department of Health & Human Services
Compound 525119: 3-Chloropropyl nonanoate

Chemical compound data from PubChem database. IUPAC Name: 3-chloropropyl nonanoate. Molecular Formula: C12H23ClO2. Molecular Weight: 234.76. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Arkansas

This is the 2021 Uniform Reporting System (URS) Output Tables for Arkansas. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence-based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: arkansas, block-grant-program, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
2011 State Profile — Mississippi

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) data table showing state profiles for Mississippi in 2011. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: mississippi, n-ssats, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Miami - Fort Lauderdale Div: Drug-Related Emergency Department Visits, 2008-2011 - All Misuse and Abuse

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving drug misuse or abuse in the Fort Lauderdale division of the Miami metropolitan area, covering 2008-2011. Drug misuse/abuse visits include the use of illicit drugs, nonmedical use of pharmaceuticals, underage drinking and visits where alcohol was combined with another drug.

Tags: drug-abuse, emergency-department, miami-fort-lauderdale, samhsa, substance-misuse
Organization: U.S. Department of Health & Human Services
Compound 525506: 6-Thia-1-heptanethiol

Chemical compound data from PubChem database. IUPAC Name: 5-methylsulfanylpentane-1-thiol. Molecular Formula: C6H14S2. Molecular Weight: 150.3. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Comparison of 2002-2004 and 2012-2014 NSDUH Substate Region Estimates

Tables showing the 2002-2004 and 2012-2014 substate area estimates and 95 percent Bayesian confidence intervals along with an indication of statistical significance of the difference

Tags: behavioral-health, mental-health, nsduh-data, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Withdrawal of cerivastatin from the world market

Cerivastatin was recently withdrawn from the market because of 52 deaths attributed to drug-related rhabdomyolysis that lead to kidney failure. The risk was found to be higher among patients who received the full dose (0.8 mg/day) and those who received gemfibrozil concomitantly. Rhabdomyolysis was 10 times more common with cerivastatin than the other five approved statins. We address three important questions raised by this withdrawal. Should we continue to approve drugs on surrogate efficacy? Are all statins interchangeable? Do the benefits outweigh the risks of statins? We conclude that decisions regarding the use of drugs should be based on direct evidence from long-term clinical outcome trials.

Tags: cerivastatin-withdrawal, drug-induced-kidney-failure, nih, rhabdomyolysis-risk, statin-safety
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For North Carolina

This is the 2020 Uniform Reporting System (URS) Output Tables for North Carolina. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-data, mental-health-services, noms-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
Compound 525521: 3-(4-Isopropoxy-phenyl)-2-methyl-propionic acid, methyl ester

Chemical compound data from PubChem database. IUPAC Name: methyl 2-methyl-3-(4-propan-2-yloxyphenyl)propanoate. Molecular Formula: C14H20O3. Molecular Weight: 236.31. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Notice of Allotment Percentages to States for Child Welfare Services State Grants - (Volume 75, Number 226)

Notice of Allotment Percentages to States for Child Welfare Services State Grants
  
  

 - This notice from the Federal Register announces the allotment percentage for fiscal years 2012 and 2013 for each state under the title IV–B Subpart 1, which is the Child Welfare Services State Grants program.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: child, fiscal, grant, policy, scope
Organization: U.S. Department of Health & Human Services
Compound 525432: 3,5,5-Trimethyl-4-thiaheptane

Chemical compound data from PubChem database. IUPAC Name: 2-butan-2-ylsulfanyl-2-methylbutane. Molecular Formula: C9H20S. Molecular Weight: 160.32. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
National Directory of Drug and Alcohol Abuse Treatment Programs 2000

The National Directory of Drug and Alcohol Abuse Treatment Programs 2000 lists federal, state, local, and private facilities that provide substance abuse treatment services. The directory includes only those treatment facilities that are licensed, certified, or otherwise approved for inclusion in the directory by their state substance abuse agencies and that responded to the 1999 Uniform Facility Data Set (UFDS) survey. The directory also includes facilities administered by the Department of Veterans Affairs, the Indian Health Service, and the Department of Defense.

Tags: alcohol-abuse-treatment, behavioral-health, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
A clustering method for repeat analysis in DNA sequences

Background
          A computational system for analysis of the repetitive structure of genomic sequences is described. The method uses suffix trees to organize and search the input sequences; this data structure has been used previously for efficient computation of exact and degenerate repeats.
        
        
          Results
          The resulting software tool collects all repeat classes and outputs summary statistics as well as a file containing multiple sequences (multi fasta), that can be used as the target of searches. Its use is demonstrated here on several complete microbial genomes, the entire Arabidopsis thaliana genome, and a large collection of rice bacterial artificial chromosome end sequences.
        
        
          Conclusions
          We propose a new clustering method for analysis of the repeat data captured in suffix trees. This method has been incorporated into a system that can find repeats in individual genome sequences or sets of sequences, and that can organize those repeats into classes. It quickly and accurately creates repeat databases from small and large genomes. The associated software (RepeatFinder), should prove helpful in the analysis of repeat structure for both complete and partial genome sequences.

Tags: dna-sequences, genome-clustering, genomic-repeats, nih, suffix-tree-analysis
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Virginia

This is the 2020 Uniform Reporting System (URS) Output Tables for Virginia. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services