AndreaBozzo/ceres-open-data-index huggingface dataset:
2015 CMHS Uniform Reporting System (URS) Table for Nebraska

2015 Center for Mental Health Services (CMHS) Uniform Reporting System (URS) Output Tables for Nebraska.  The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, mental-health-services, nebraska, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
2020 Uniform Reporting System (URS) Table For Republic of Marshall Islands

This is the 2020 Uniform Reporting System (URS) Output Tables for Republic of Marshall Islands. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, community-mental-health, mental-health-services, national-outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression

We examined the stage specificity and heterogeneity of 18p11 alterations in a series of tumors representing 96 microdissected samples. Significant loss of heterozygosity (LOH) (63%) was found, with 56% occurring early in ductal carcinoma in situ. Although most cases indicated LOH was clonally inherited, heterogeneity for 18p LOH occurred in 27% of tumors. When compared with other LOH data, 18p LOH was found in conjunction with allelic deletion on 3p, 9p, 17p and 17q, while 13q, 16q, and 11p were less frequently associated. These analyses suggest chromosome 18p11 alteration is a common and early event in breast disease.

Tags: breast-cancer, chromosome-18p, loh, nih, tumor-progression
Organization: U.S. Department of Health & Human Services
Youth Information Form: Data from Runaway and Homeless Youth Programs, 1987-1990

These data were gathered from federally funded runaway and homeless youth shelters during 1988-1989.  Data were collected on approximately 87,000 youth who received services from runaway and homeless youth programs. The following types of information are included in the data set:  demographic characteristics, youth and family presenting problems at intake (including history of abuse and neglect), and services provided by the shelter.

Investigators: Office of Human Development Services/ACYF

Tags: abuse, care, ndacan, policy, reporting
Organization: U.S. Department of Health & Human Services
2010 State Profile — Georgia

This state profile includes data from facilities in Georgia that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Georgia. In Georgia, 243 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 18,928 clients in substance abuse treatment on March 31, 2010. The survey response rate in Georgia was 88.1%.

Tags: addiction-services, georgia, n-ssats, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
Compound 525649: N,N-Dimethyl-N'-propyl-benzamidine

Chemical compound data from PubChem database. IUPAC Name: N,N-dimethyl-N'-propylbenzenecarboximidamide. Molecular Formula: C12H18N2. Molecular Weight: 190.28. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 525460: 3-Thia-1-octene

Chemical compound data from PubChem database. IUPAC Name: 1-ethenylsulfanylpentane. Molecular Formula: C7H14S. Molecular Weight: 130.25. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
Compound 528387: 2,3,5-Trichloro-6-hydroxybenzaldehyde

Chemical compound data from PubChem database. IUPAC Name: 2,3,5-trichloro-6-hydroxybenzaldehyde. Molecular Formula: C7H3Cl3O2. Molecular Weight: 225.5. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
2016 Uniform Reporting System (URS) Table for Massachusetts

This is the 2016 Uniform Reporting System (URS) Output Tables for Massachusetts. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant, massachusetts, mental-health-services, outcome-measures, samhsa
Organization: U.S. Department of Health & Human Services
2010 State Profile — Utah

This state profile includes data from facilities in Utah that reported to N-SSATS for the survey reference date March 31, 2010. Data were collected on the location, characteristics, services offered, and number of clients in treatment at alcohol and drug abuse treatment facilities (both public and private) in Utah. In Utah, 146 substance abuse treatment facilities were included in the 2010 N-SSATS, reporting that there were 12,993 clients in substance abuse treatment on March 31, 2010. The survey response rate in Utah was 97.5%.

Tags: alcohol-drug-abuse, n-ssats, samhsa, substance-abuse-treatment, utah
Organization: U.S. Department of Health & Human Services
2018 Uniform Reporting System (URS) Table for Michigan

This is the 2018 Uniform Reporting System (URS) Output Tables for Michigan. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, samhsa, substance-abuse
Organization: U.S. Department of Health & Human Services
A modification of Representational Difference Analysis, with application to the cloning of a candidate in the Reelin signalling pathway

Background
          cDNA-RDA is one of the subtractive cloning techniques used to isolate differentially expressed genes between two complex cDNA populations. In the present study we present a modification of the protocol described by Hubank and Schatz.
        
        
          Results
          In the post-hybridization mix, the 5'-ends of homoduplexes of interest (tester-tester) are filled-in with α-thio-deoxynucleotides. Unprotected duplexes, as well as the single-stranded DNA fragments, are degraded using ExoIII and Mung Bean Nuclease, prior to PCR subtraction, resulting in less complex difference products. We illustrate this modification by the cloning of a new gene which is differentially expressed in normal, reelin and Dab1 mutant mice and is a candidate member of the Reelin signalling pathway involved in brain development.
        
        
          Conclusion
          We propose a modification of cDNA-RDA that may reduce the complexity of the post-hybridization mix and thus facilitate the amplification of differentially expressed products.

Tags: brain-development, cdna-rda, gene-expression, nih, reelin-signaling
Organization: U.S. Department of Health & Human Services
NSDUH 2023 Questionnaire

Browse the English in-person and web interview questionnaires for the 2023 National Survey on Drug Use and Health (NSDUH). The documents provide the exact questions given to respondents in their full context, along with the skip patterns that determined whether a person was asked a question or not. There is also information on which sections were interviewer administered when conducted in-person, and a section that summarizes changes made to the questionnaire for 2023.

Tags: behavioral-health-survey, mental-health, nsduh-questionnaire, samhsa, substance-use
Organization: U.S. Department of Health & Human Services
Brief report on the effect of providing single versus assorted brand name condoms to hospital patients: a descriptive study

Objectives
          This study examined condom acquisition by persons in a hospital setting when single versus assorted brand name condoms were provided.
        
        
          Methods
          Condom receptacles were placed in exam rooms of two clinics. During Phase 1, a single brand name was provided; for Phase 2, assorted brand names were added. Number of condoms taken was recorded for each phase.
        
        
          Results
          For one clinic there was nearly a two-fold increase in number of condoms taken (Phase 1 to Phase 2); for the second clinic there was negligible difference in number of condoms taken.
        
        
          Conclusions
          The provision of assorted brand name condoms, over a single brand name, can serve to increase condom acquisition. Locations of condoms and target population characteristics are related factors.

Tags: condom-access, hospital-patients, nih, risk-reduction, sexual-health
Organization: U.S. Department of Health & Human Services
IgVH genes from different anatomical regions, with different
		  histopathological patterns, of a rheumatoid arthritis patient suggest cyclic
		  re-entry of mature synovial B-cells in the hypermutation process

In the present study 55 IgVH genes amplified from three different
			 anatomical regions of a rheumatoid arthritis (RA) patient were analyzed, adding
			 further information on synovial B-cell maturation and recirculation in RA. This
			 analysis demonstrated somatically mutated IgVh genes in all regions studied,
			 with amino acid deletions and mixed IgVh molecules, suggesting the existence of
			 a novel pathway to generate (auto) antibody specificities. Comparison of amino
			 acid sequences of amplified genes that belong to the VH1 family (with
			 predominantly the same germline counterpart) exhibited strong homology,
			 indicating an apparently conserved mutational pattern. This suggests that the
			 number of antigens that activate B cells in different locations is restricted.
			 The most striking result was the finding of clonally related sequences in
			 different anatomical regions, indicating a recirculation of activated B cells
			 between the different affected joints.

Tags: b-cell-recirculation, igvh-genes, nih, rheumatoid-arthritis, synovial-tissue
Organization: U.S. Department of Health & Human Services
TNF-α induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide

Background
          MAdCAM-1 is an adhesion molecule expressed in Peyer's patches and lymphoid tissues which is mobilized by cytokines like TNF-α and is a major determinant of lymphocyte trafficking to the gut in human inflammatory bowel disease (IBD). It has been suggested that both reactive oxygen and nitrogen metabolites participate in regulating adhesion molecule expression in response to TNF-α.
        
        
          Methods
          To examine how exogenous and endogenous sources of NO modulate MAdCAM-1 induction by TNF-α, we pre-treated mouse lymphatic endothelial cells with either long or short acting NO donors prior to TNF-α-stimulation, and measured MAdCAM-1 induction at 24 h.
        
        
          Results and Discussion
          DETA-NO, a long-acting NO donor, and SperNO, a rapid releasing NO donor both inhibited TNF-α-stimulated MAdCAM-1 expression in a concentration dependent manner. Both NO donors also reduced a4b7-dependent lymphocyte endothelial adhesion. Inhibition of endogenous NO production by either L-NAME, a non-selective NOS inhibitor, or by 1400 w, a selective iNOS inhibitor failed to induce, or potentiate TNF-α regulated MAdCAM-1 expression.
        
        
          Conclusions
          Exogenous NO donors may be beneficial in the treatment of IBD, while endogenous nitric oxide synthases may be less effective in controlling adhesion molecule expression in response to cytokines.

Tags: inflammatory-bowel-disease, madcam-1-expression, nih, nitric-oxide, tnf-alpha
Organization: U.S. Department of Health & Human Services
NSDUH 2019 Methodological Resource Book (MRB)

Use this collection to provide context for estimates from the 2019 National Survey on Drug Use and Health (NSDUH). This collection includes materials used to conduct the survey, reports on how the survey was conducted, and reports on how the data were processed. The Statistical Inference Report details how the data were analyzed for reports and tables, which may be useful for data users looking to do their own analysis.

Tags: data-analysis, mental-health, samhsa, substance-use, survey-methodology
Organization: U.S. Department of Health & Human Services
Compound 525623: N,N-Dimethyl-N'-decyl-p-chlorobenzamidine

Chemical compound data from PubChem database. IUPAC Name: 4-chloro-N'-decyl-N,N-dimethylbenzenecarboximidamide. Molecular Formula: C19H31ClN2. Molecular Weight: 322.9. This dataset contains comprehensive chemical information including structural data, physical properties, and biological activities. Useful for drug discovery, chemical research, and educational purposes.

Tags: chemistry, compound, pubchem, research, science
Organization: U.S. Department of Health & Human Services
THEORY OF CHANGE: Illinois Trauma Focus Model for Reducing Long-term Foster Care

This presentation explains how the Illinois Permanecy Innovations Initiative (PII) project expects to increase rates of permanency for the target population and it describes the intervention being used, Trauma Affect Regulation: Guide for Education and Therapy (TARGET), a strength-based approach to education and therapy when youth and their families have been affected by trauma or experience a high level of stress related to adverse experiences.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: care, foster, intervention, policy, trauma
Organization: U.S. Department of Health & Human Services
New York City – 5 Boros: Drug-Related Emergency Department Visits, 2004-2011 - Suicide Attempts

Excel file with estimates, rates, relative standard errors, trends and confidence intervals for all drug-related emergency department (ED) visits involving suicide attempts in New York City (5 boroughs), covering 2004-2011.  Drug-related suicide attempts include visits for drug overdoses and for suicide attempts by other means (e.g., using a firearm) if drugs were involved or related to the suicide attempt.

Tags: drug-overdose, emergency-department, nyc-boroughs, samhsa, suicide-attempts
Organization: U.S. Department of Health & Human Services
CFSR Technical Bulletin #13A

This TB provides updates on the measurement and case review sampling framework for CFSR Round 4. The primary purpose is to announce CFSR Round 4 statewide data indicator (SWDI) national performance values. This amendment also provides other updates and clarification regarding technical aspects of measurement and sampling. A table is included in the amendment that identifies substantial changes to the original bulletin.

Metadata-only record linking to the original dataset. Open original dataset below.

Tags: assessment, child, policy, reporting, scope
Organization: U.S. Department of Health & Human Services
Research Article: Arthritis Research

This is a brief review of the third volume of the series edited by AN Theofilopoulos, "Current Directions in Autoimmunity". This hard-cover volume comprises 282 pages, 46 figures and 14 tables. The book has a cover price of 196 Swiss Francs, or 255 Deutschmarks, or 170.50 US dollars.

Tags: arthritis-research, autoimmunity, nih, rheumatology
Organization: U.S. Department of Health & Human Services
2021 Uniform Reporting System (URS) Table For Indiana

This is the 2021 Uniform Reporting System (URS) Output Tables for Indiana. The URS state reporting system is collected annually to support the Community Mental Health Services Block Grant program. State Mental Health Authorities report on National Outcome Measures (NOMS), evidence based practices, and utilization measures providing an overview of state mental health delivery systems.

Tags: block-grant-program, mental-health-services, national-outcome-measures, samhsa, urs-data
Organization: U.S. Department of Health & Human Services
Cardiac rehabilitation: a comprehensive review

Cardiac rehabilitation (CR) is a commonly used treatment for men and women with cardiovascular disease. To date, no single study has conclusively demonstrated a comprehensive benefit of CR. Numerous individual studies, however, have demonstrated beneficial effects such as improved risk-factor profile, slower disease progression, decreased morbidity, and decreased mortality. This paper will review the evidence for the use of CR and discuss the implications and limitations of these studies. The safety, relevance to special populations, challenges, and future directions of CR will also be reviewed.

Tags: cardiac-rehabilitation, cardiovascular-disease, exercise-therapy, nih, secondary-prevention
Organization: U.S. Department of Health & Human Services
Scanning laser Doppler is a useful technique to assess foot cutaneous
		  perfusion during femoral artery cannulation

Background:
          Measurement of cardiac output and extravascular lung water in
				critically ill patients using femoral artery double-indicator dilution involves
				femoral artery catheterization. The potential risk of vascular compromise to
				the limb may be exacerbated in patients receiving vasopressors. The utility of
				scanning laser Doppler flowmetry to measure changes in pedal perfusion
				following catheterization was assessed.
        
        
          Results:
          There were no significant changes in mean occlusion pressures or
				in cutaneous perfusion between either leg or between measurement time points,
				immediately after or 24 h following insertion of the catheters.
        
        
          Conclusions:
          Scanning laser Doppler flowmetry is easily used to assess changes
				in foot perfusion and the effect of interventions that may reduce blood flow to
				the skin of the foot. Femoral artery catheterization for double-indicator
				dilution measurements does not reduce calf occlusion pressures or foot skin
				perfusion in patients receiving vasopressor drugs.

Tags: cutaneous-blood-flow, femoral-artery-cannulation, foot-perfusion, laser-doppler-flowmetry, nih
Organization: U.S. Department of Health & Human Services
Supracervical hysterectomy versus total abdominal hysterectomy: perceived effects on sexual function

Background
          Our investigation sought to compare changes in sexual function following supracervical hysterectomy (SCH) and total abdominal hysterectomy (TAH).
        
        
          Methods
          A retrospective chart review was performed to identify all patients who underwent supracervical hysterectomy or total abdominal hysterectomy at a tertiary care center. Patients who met criteria for participation were sent a one page confidential, anonymous questionnaire to assess sexual function experienced both pre- and postoperatively. A total of 69 patients in each group were eligible for participation. A multiple logistic regression model was used to analyze measured variables.
        
        
          Results
          Forty-eight percent (n = 33) of women undergoing a SCH returned the questionnaire, while 39% (n = 27) of those undergoing a TAH chose to participate. There were no significant demographic differences between the two groups. Patients who underwent TAH reported worse postoperative sexual outcome than SCH patients with respect to intercourse frequency, orgasm frequency and overall sexual satisfaction (P = 0.01, 0.03, and 0.03, respectively). Irrespective of type of hysterectomy, 35% of patients who underwent bilateral salpingoophorectomy (BSO) with hysterectomy experienced worse overall sexual satisfaction compared to 3% of patients who underwent hysterectomy alone (P = 0.02).
        
        
          Conclusions
          Our data suggest that TAH patients experienced worse postoperative sexual function than SCH patients with respect to intercourse frequency and overall sexual satisfaction. Irrespective of type of hysterectomy, patients who underwent bilateral salpingoophorectomy experienced worse overall sexual satisfaction.

Tags: hysterectomy-outcomes, nih, postoperative-effects, sexual-function, surgical-comparison
Organization: U.S. Department of Health & Human Services
2012 State Profile - Alaska

This is a National Survey of Substance Abuse Treatment Services (N-SSATS) annual report showing the state profile for Alaska in 2012. N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 States, the District of Columbia, and other U.S. jurisdictions.

Tags: addiction-services, alaska-health-services, n-ssats, samhsa, substance-abuse-treatment
Organization: U.S. Department of Health & Human Services
National Survey of Substance Abuse Treatment Services (N-SSATS): 2012 Data on Substance Abuse Treatment Facilities

This report presents results from the 2012 National Survey of Substance Abuse Treatment Services (N-SSATS), an annual census of facilities providing substance abuse treatment. Conducted by the Substance Abuse and Mental Health Services Administration (SAMHSA), the N-SSATS is designed to collect data on the location, characteristics, and use of alcohol and drug abuse treatment facilities and services throughout the 50 states, the District of Columbia, and other U.S. jurisdictions

Tags: addiction-services, behavioral-health-services, samhsa, substance-abuse-treatment, treatment-facilities
Organization: U.S. Department of Health & Human Services
Denver: Drug-Related Emergency Department Visits, 2004-2011 - Adverse Reactions

Excel file with estimates, rates, relative standard errors, trends and confidence intervals, covering 2004-2011 for emergency department visits involving adverse reactions in the Denver metropolitan area. It includes ED visits in which an adverse health consequence (e.g., side effects or an allergic reaction) resulted when taking prescription drugs, over-the-counter medications, or dietary supplements as prescribed or recommended.  This analytic category does not include drug misuse or abuse.File includes data for over 500 drugs, including illicit drugs, prescription and over-the-counter medications, dietary supplements, inhalants and alcohol.  Includes total visits, gender, age group, race/ethnicity, outcome of visit, drug combinations, number of drugs involved in visit, drug frequency, and drugs confirmed by toxicology.Additional detail is provided for illicit drugs, psychotherapeutic drugs, central nervous system (CNS) drugs, respiratory drugs and cardiovascular drugs.

Tags: adverse-drug-reactions, drug-related-events, emergency-department-visits, pharmacoepidemiology, samhsa
Organization: U.S. Department of Health & Human Services