AndreaBozzo/ceres-open-data-index huggingface dataset:
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Hippocampus; ECLIA)

Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of inflammasome activation in the brains of mice that were housed in the International Space Station (ISS) for 37 days. C57BL/6 mice were launched to the ISS as part of NASA’s Rodent Research 1 Mission on SpaceX-4 CRS-4 Dragon cargo spacecraft from September 21st, 2014, to October 25th, 2014. Dissected mouse brains from that mission were analyzed by immunoblotting of inflammasome signaling proteins and Electrochemiluminescence Immunoassay (ECLIA) for inflammatory cytokine levels. Our data indicate decreased inflammasome activation in the brains of mice that were housed in the ISS for 37 days when compared to the brains of mice that were maintained on the ground, and in mice corresponding to the baseline group that were sacrificed at the time of launching of SpaceX-4. Moreover, we did not detect any significant changes in the expression levels of the pro-inflammatory cytokines TNF-alpha, IL-2, IFN-gamma, IL-5, IL-6, IL-12p70 and IL-10 between the ground control and the flight groups. Together, these studies suggest that spaceflight results in a decrease in the levels of innate immune signaling molecules that govern inflammasome signaling in the brain of mice. This dataset derives results from the ECLIA assay using brain tissue.

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Organization: National Aeronautics and Space Administration
Fermi LAT Fourth AGN Catalog

This is the third update to the fourth catalog of active galactic nuclei (AGNs) detected by the Fermi Large Area Telescope (LAT). This version (4LAC-DR3) derives from the third data release of the 4FGL catalog based on 12 years of gamma-ray data with energies greater than 50 MeV. The spectral parameters, spectral energy distributions (SEDs), yearly light curves, and associations have been updated for all sources. The catalog contains includes 3407 AGN located at high Galactic latitudes (|b| &gt; 10 degrees). This database table was first ingested by the HEASARC in February 2010. It was last updated (to the 4LAC-DR3 version) in June 2023 using electronic data obtained from the Fermi Science Support Center (FSSC). That data is available at &lt;a href="https://fermi.gsfc.nasa.gov/ssc/data/access/lat/4LACDR3/"&gt;https://fermi.gsfc.nasa.gov/ssc/data/access/lat/4LACDR3/&lt;/a&gt;. Note that this table does not contain the low-latitude sources given in a separate file there, which are not formally a part of the catalog. This is a service provided by NASA HEASARC .

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Organization: National Aeronautics and Space Administration
EXOSAT Observation Log

This database table contains the EXOSAT observation log. This is a complete list of all EXOSAT observations, observing modes, and principal investigators. The log can be used to find out which targets were observed by EXOSAT, who observed them, and the current state of the data analysis. The HEASARC revised this database table in August, 2005, in an effort to modernize its parameter names and add Galactic coordinates. This is a service provided by NASA HEASARC .

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Organization: National Aeronautics and Space Administration
Effects of spaceflight on murine skeletal muscle gene expression

Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts towards faster muscle fiber types. To identify changes in gene expression that may underlie these adaptations, microarray expression analysis was performed on gastrocnemius from mice flown on the STS-108 shuttle flight (11 days, 19 hours) versus mice maintained on earth for the same period. Additionally, to identify changes that were due to unloading and reloading, microarray analyses were conducted on calf muscle from ground-based mice subjected to hindlimb suspension (12 days) and mice subjected to hindlimb suspension plus a brief period of reloading (3.5 hours) to simulate the time between landing and sacrifice of the spaceflight mice.

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Organization: National Aeronautics and Space Administration
ABoVE: Wetland Inundation Coverage at Yukon Flats, AK and PA Delta, Canada, 2017-2019

This dataset provides time series of wetland inundation coverage maps and corresponding inundation frequency maps at ~10-meter resolution estimated every 12 days during the free-water period (May to October) for the years 2017-2019 over the Yukon Flats (YK) portion of the Yukon River, Alaska, USA, and the Peace-Athabasca Delta (PAD), Alberta, Canada. Wetland inundation coverage was determined by a two-step modified decision-tree classification approach that first used Sentinel-1 C-band SAR to identify likely inundated areas across a study site and was followed by a decision-tree classification step with C-band SAR backscatter statistics thresholds to distinguish among different inundation components. The result of this process was five classes for each inundation map, namely Open Water (OW), Floating Plants (FP), Emergent Plants (EP), Flooded Vegetation (FV), and Dry Land (DRY). After all the individual (every 12 days) inundation coverage maps were derived for a study site, they were generalized to two-class maps which maintained only inundation status. These generalized maps were then stacked and summarized to produce the inundation frequency map for the site. In these maps, higher values signify more frequently inundated areas, with the maximum value representing permanently inundated pixels. The Sentinel-1 inundation mapping capability demonstrated here provided frequent, broad-scale mapping of different wetland inundation components. Integration of such products with process-based methane (CH4) models would improve simulation of CH4 emissions from wetlands.

Tags: earth-science-ecosystems-biosphere-aquatic-ecosystems-wetlands, earth-science-surface-water-terrestrial-hydrosphere-surface-water-processes-measurements-inunda
Organization: National Aeronautics and Space Administration
Impact of simulated microgravity on the growth and proteomic profile of Enterobacter cloacae

The proteomics experiment involved analyzing the protein expression profiles of Enterobacter cloacae under different gravity conditions simulated in High Aspect Ratio Vessels (HARVs). The three conditions studied were normal gravity (NG), inverted normal gravity (INV), and low shear modeled microgravity (LSMMG). The goal was to assess how E. cloacae adapts to microgravity, given its relevance to astronaut health during spaceflight. By comparing the proteomic profiles across these conditions, the study identified significant changes in protein expression in LSMMG and INV compared to NG.

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Organization: National Aeronautics and Space Administration
Hubble Source Catalog Summary Search

The Hubble Source Catalog (HSC) is designed to optimize science from the Hubble Space Telescope \nby combining the tens of thousands visit-based source lists in the Hubble Legacy Archive (HLA) \ninto a single master catalog. \nThe HSC Summary search displays a single row entry for each object,\nas defined by a set of detections that have been cross-matched and hence are believed to be a single object.\nAveraged values for magnitudes and other relevant parameters are provided.\nThe catalog currently contains over 16 million entries.

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Organization: National Aeronautics and Space Administration
CGRO/EGRET Photon Lists and Maps

The Energetic Gamma-Ray Experiment Telescope (EGRET), which operated from 1991-April until 2000-May, was sensitive to photons in the energy range from about 30 MeV to over 20 GeV, the highest energies accessible by the CGRO instruments, and, like COMPTEL, was an imaging instrument. This catalog includes photon lists in qvp files, with one file for each EGRET viewing period. Photons which pass an energy-dependent cut on zenith angle (to exclude earth-albedo gamma rays) are processed into maps of photon counts for a standard set of energy ranges. Exposure and intensity (counts divided by exposure) maps are generated for each counts map. The counts maps typically include photons detected up to 40 degrees from the instrument axis. Most analysis has been done using data within 30 degrees of the instrument axis, where the point-spread function is narrower and the effective area greater than further off axis. All EGRET data files in the archive are the final versions, produced after the end of the mission. More detailed information about EGRET, EGRET data, and EGRET data analysis software can be found at: &lt;pre&gt; &lt;a href="https://heasarc.gsfc.nasa.gov/docs/cgro/egret/egret_doc.html"&gt;https://heasarc.gsfc.nasa.gov/docs/cgro/egret/egret_doc.html&lt;/a&gt; &lt;/pre&gt; The data contained in this database table was supplied by the CGRO Science Support Center. The contents this table was last updated in May 2001. Galactic coordinates were added to the table by the HEASARC in August 2005. This is a service provided by NASA HEASARC .

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Organization: National Aeronautics and Space Administration
The International Space Station Has a Unique and Extreme Microbial and Chemical Environment Driven by Use Patterns

Space habitation provides unique challenges in built environments isolated from Earth. We produced a 3D map of the microbes and metabolites throughout the International Space Station (ISS), with 803 samples collected during space flight, including controls. We find that the use of each of the nine sampled modules within the ISS strongly drives the microbiology and chemistry of the habitat. Relating the microbiology to other Earth habitats, we find that, as with human microbiomes, built environment microbiomes also align naturally along an axis of industrialization, with the ISS providing an extreme example of an industrialized environment. We demonstrate the utility of culture-independent sequencing for microbial risk monitoring, especially as the location of sequencing moves to space. The resulting resource of chemistry and microbiology in the space-built environment will guide long-term efforts to maintain human health in space for longer durations.

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Organization: National Aeronautics and Space Administration
Transcription profiling of S. cerevisiae cultures grown under low shear-modeled microgravity

The goal of this study was to assess whether low shear-modeled microgravity (LSMMG) affects yeast genomic expression patterns using the powerful tool of whole genome microarray hybridization. We determined changes in the yeast model organism, Saccharomyces cerevisisae, when grown in LSMMG using the rotating High Aspect Ratio Vessel (HARV). A significant number of genes were up- or down-regulated by at least two fold in cells that were grown for 5 generations or 25 generations in HARVs. We identified genes in cell wall integrity signaling pathways containing MAP kinase cascades that may provide clues to novel physiological responses of eukaryotic cells to the external stress of a low-shear modeled microgravity environment. A comparison of the microgravity response to other environmental stress response (ESR) genes showed that 26% of the genes that respond ,significantly to LSMMG are involved in a general environmental stress response, while 74% of the genes may represent a unique transcriptional response to microgravity. In addition, we found changes in genes involved in budding, cell polarity establishment, and cell separation that confirm our hypothesis that exposure to LSMMG causes changes in gene transcription resulting in a phenotypic response. The results of the study provide interesting clues to potential mechanisms involved in the response to, adaptation to, and survival of eukaryotic cells in a microgravity environment and our findings may have important health implications for human spaceflight. Experiment Overall Design: Four conditions are compared with three replicates each: yeast grown in low-shear modeled microgravity (HARV bioreactor) for 5 and 25 generations; yeast grown in a horizontal (non-LSMMG) HARV bioreactor for 5 and 25 generations.

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Organization: National Aeronautics and Space Administration
ACTIVATE Falcon In-Situ Meteorological and Navigational Data

ACTIVATE_MetNav_AircraftInSitu_Falcon_Data is the meteorological and navigational data collected onboard the HU-25 Falcon aircraft via in-situ instrumentation during the ACTIVATE project. ACTIVATE was a 5-year NASA Earth-Venture Sub-Orbital (EVS-3) field campaign. Marine boundary layer clouds play a critical role in Earth’s energy balance and water cycle. These clouds cover more than 45% of the ocean surface and exert a net cooling effect. The Aerosol Cloud meTeorology Interactions oVer the western Atlantic Experiment (ACTIVATE) project was a five-year project that provides important globally-relevant data about changes in marine boundary layer cloud systems, atmospheric aerosols and multiple feedbacks that warm or cool the climate. ACTIVATE studied the atmosphere over the western North Atlantic and sampled its broad range of aerosol, cloud and meteorological conditions using two aircraft, the UC-12 King Air and HU-25 Falcon. The UC-12 King Air was primarily used for remote sensing measurements while the HU-25 Falcon will contain a comprehensive instrument payload for detailed in-situ measurements of aerosol, cloud properties, and atmospheric state. A few trace gas measurements were also onboard the HU-25 Falcon for the measurements of pollution traces, which will contribute to airmass classification analysis. A total of 150 coordinated flights over the western North Atlantic occurred through 6 deployments from 2020-2022. The ACTIVATE science observing strategy intensively targets the shallow cumulus cloud regime and aims to collect sufficient statistics over a broad range of aerosol and weather conditions which enables robust characterization of aerosol-cloud-meteorology interactions. This strategy was implemented by two nominal flight patterns: Statistical Survey and Process Study. The statistical survey pattern involves close coordination between the remote sensing and in-situ aircraft to conduct near coincident sampling at and below cloud base as well as above and within cloud top. The process study pattern involves extensive vertical profiling to characterize the target cloud and surrounding aerosol and meteorological conditions.

Tags: earth-science-atmospheric-water-vapor-atmosphere, earth-science-atmospheric-water-vapor-atmosphere-water-vapor-indicators, earth-science-atmospheric-water-vapor-atmosphere-water-vapor-indicators-water-vapor, earth-science-atmospheric-winds-atmosphere, earth-science-atmospheric-winds-atmosphere-surface-winds, earth-science-atmospheric-winds-atmosphere-surface-winds-u-v-wind-components, earth-science-atmospheric-winds-atmosphere-surface-winds-wind-direction, earth-science-atmospheric-winds-atmosphere-surface-winds-wind-speed, earth-science-atmospheric-winds-atmosphere-upper-level-winds, earth-science-atmospheric-winds-atmosphere-upper-level-winds-u-v-wind-components, earth-science-atmospheric-winds-atmosphere-upper-level-winds-wind-direction, earth-science-atmospheric-winds-atmosphere-upper-level-winds-wind-speed
Organization: National Aeronautics and Space Administration
Galaxy Evolution Explorer (GALEX) Observation Log

This table contains the Galaxy Evolution Explorer (GALEX) observation log of the extant and planned observations to be made by this satellite observatory. The Galaxy Evolution Explorer (GALEX) is a NASA Small Explorer Mission launched on April 28, 2003. GALEX has been performing the first Space Ultraviolet sky survey. Five imaging surveys in each of two bands (FUV: 1350-1750 Angstroms and NUV: 1750-2800 Angstroms) range from an all-sky survey (limiting m&lt;sub&gt;AB&lt;/sub&gt; ~ 20 - 21) to an ultra-deep survey of 4 square degrees (limiting m&lt;sub&gt;AB&lt;/sub&gt; ~ 26). Three spectroscopic grism surveys (spectral resolution R = 100 - 300) are underway with various depths (m&lt;sub&gt;AB&lt;/sub&gt; ~ 20 - 25) and sky coverage (100 to 2 square degrees) over the 1350 - 2800 Angstroms spectral range. The instrument includes a 50-cm modified Ritchey-Chretien telescope, a dichroic beam splitter and astigmatism corrector, two large, sealed-tube microchannel plate detectors to simultaneously cover the two bands and the 1.2-degree field of view. A rotating wheel provides either imaging or grism spectroscopy with transmitting optics. The GALEX mission also includes an Associate Investigator program for additional observations and supporting data analysis which supports a wide variety of investigations made possible by the first UV sky survey. The HEASARC provides this table of GALEX observations as an assistance to the high-energy astrophysics community, e.g., to enable cross-correlations of GALEX with X-ray observations. The GALEX data are available via MAST at &lt;a href="http://galex.stsci.edu/"&gt;http://galex.stsci.edu/&lt;/a&gt;. More information about GALEX can be found at &lt;a href="http://www.galex.caltech.edu/"&gt;http://www.galex.caltech.edu/&lt;/a&gt; and &lt;a href="https://asd.gsfc.nasa.gov/archive/galex/"&gt;https://asd.gsfc.nasa.gov/archive/galex/&lt;/a&gt;. This table was first created in July 2010 using the input file &lt;a href="http://sherpa.caltech.edu/gips/ref/galex_obs_status.csv"&gt;http://sherpa.caltech.edu/gips/ref/galex_obs_status.csv&lt;/a&gt; obtained from the Caltech GALEX site. This table is updated within a week of the update of the original file. This is a service provided by NASA HEASARC .

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Organization: National Aeronautics and Space Administration
Effect of varying amounts of simulated lunar soil batch #005 upon growth of lettuce explants

The following general conclusions can be made concerning the use of tissue culture for assaying the effects of mineral elements from simulated lunar soil or other mineral samples: The method used here is a very sensitive one for showing that soluble materials are reaching the tissue explant. The effects found (inhibiting) are very probably caused by excess toxic materials or competition of non-essential elements with essential elements rather than pH changes because previously pH has been found- to have relatively little effect over a wide range. Any stimulatory effect of the simulated lunar soil will probably appear at concentrations below those used in these experiments. If this is the case, the method is much less wasteful of mineral materials than methods in which pre-grown callus is treated with mineral materials.  Measurements of uptake of minerals will be difficult in this system because of the relatively small growth obtainable from the tissue and also because of the apparently large background of minerals contributed by the purified agar.

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Organization: National Aeronautics and Space Administration
Spitzer Extragalactic First Look Survey WIYN/Hydra Spectroscopic Catalog

The Extragalactic First Look Survey is composed of 4 square degrees of imaging with MIPS and IRAC centered at J1718+5930, with extensive ancillary data from ground-based optical and radio telescopes. As one of the first observations made with Spitzer after the completion of Science Verification at the end of 2003 November, the aim of this 67 hr survey was to characterize the extragalactic source populations observed with Spitzer down to sub-millijansky levels in the mid-infrared. \n\nThis catalog presents data on the WIYN/Hydra spectra described in Marleau et al. (2007).

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Organization: National Aeronautics and Space Administration
2MASS Calibration Merged Point Source Information Table

Photometric calibration for 2MASS was performed using observations of calibration fields made at regular intervals during each night of survey operations. Measurements of standard stars in the fields were used to derive the photometric zero point offsets as a function of time during each night. Atmospheric extinction coefficients were derived from 2MASS observations made over long periods.\n\n2MASS calibration fields, or tiles, are 1° long in declination and approximately 8.5' wide in right ascension. There are 35 regular survey calibration fields distributed at approximately two hour intervals in right ascension near declinations of approximately -30°, 0° and +30°. An additional five calibration fields were defined in and around the Large and Small Magellanic Clouds to support the deep observation (6x) campaign towards the end of survey operations.\n\nOver the course of the survey, the regular calibration fields were scanned between 562 and 3692 times in nominally photometric conditions. Equatorial fields were observed from both observatories, so were observed more frequently than those near ±30° which were observed with only one telescope. The special Magellanic Cloud calibration fields were observed 108 to 468 times between November 2000 and February 2001.\n\nThe following table contains brief descriptions of the entries in the Survey, 6x and Calibration Merged Point Source Information Tables. The merged source tables contain the mean positions magnitudes and uncertainties for sources detected multiple times in each of the 2MASS data sets. The merging was carried out using an autocorrelation of the respective databases to identify groups of extractions that are positionally associated with each other, all lying within a 1.5" radius circular region. A number of confirmation statistics are also provided in the tables that can be used to test for source motion and/or variability, and the general quality of the merge.

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Organization: National Aeronautics and Space Administration
Proteomics and Transcriptomics analysis of Arabidopsis Seedlings in Microgravity

On Earth plants are constantly exposed to a gravitational field of 1G. Gravity affects a plant in every step of its development. Germinating seedlings orient their radicle and hypocotyl and growing plants position organs at a specific Gravitropic Set-point Angle dictated by the asymmetric distribution of auxin depending on the gravity vector. Hence gravitropism is one of the fundamental growth responses in plants. For any experiment studying the effects of gravity on plants, the ultimate control is the microgravity in space. In this study, Arabidopsis seeds were flown to the International Space Station and allowed to germinate and grow for 3 days in microgravity. Arabidopsis Wild Type Col-0 seeds were plated onto twenty-two 60mm Petri plates, loaded into PDFUs and inserted 4 Biological Research in Canisters (BRICs). Approximately 800 seeds were sterilized, plated on each 60mm Petri plates and cold stratified for 16 hours followed by 2 hours of white light treatment. The BRICs were maintained at 4C until spaceflight to ensure seed germination in microgravity. After 3 days of germination and growth, the seedlings were fixed by injecting RNAlater into the chamber. They were kept at ambient temperature for 12 hours followed by freezing at -80C. An additional 22 plates were used as ground controls. After the spaceflight, tissue from five plates was pooled to make each of three replicates. Both membrane and soluble proteins were extracted from the pooled seedlings. Proteins were trypsin digested, labelled with iTRAQ and identified using tandem mass spectrometry.

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Organization: National Aeronautics and Space Administration
Suzaku Master Catalog

This database table records high-level information for each Suzaku observation and provides access to the data archive. Each record is associated with a single observation. An observation contains data from all instruments on board Suzaku. The Suzaku satellate operated from July 2005 till September 2015. This database table was generated at the Suzaku proceesing site with the final data reprocessing (September 2016) after the mission stopped operating. During operation, it was updated on daily basis. This is a service provided by NASA HEASARC .

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Organization: National Aeronautics and Space Administration