{"question": "Most essential drugs should be formulated as", "exp": ".", "cop": 2, "opa": "No compound", "opb": "Single compound", "opc": "Multiple compounds", "opd": "Fixed dose combinations", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0f5da178-ab9b-46c7-b8b9-e1d22dc37cb9", "choice_type": "single"} {"question": "The roof of the olfactory region is formed by", "exp": "The bony pa of the olfactory region is formed by: The vomer and The perpendicular plate of ethmoid.It's margins receive contributions from nasal spine of the frontal bone, the rostrum of the sphenoid and the nasal crests of the nasal palatine and maxillary bones. The cailaginous pa is formed by: The septal cailage and The septal processes of the inferior nasal cailages. The cuticular pa or lower end is formed by fibrofatty tissue covered by skin. Ref BDC volume 3,sixth edition", "cop": 2, "opa": "Nasal bone", "opb": "Cribriform plate of ethmoid", "opc": "Sphenoid", "opd": "Temporal bone", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "92ebf70b-dfeb-46d4-8b37-583222720163", "choice_type": "single"} {"question": "Multiple cutaneous sebaceous adenoma are seen in", "exp": "Ref: Hall manual of skin", "cop": 3, "opa": "Gardener's syndrome", "opb": "Turcott's syndrome", "opc": "Muir Torre syndrome", "opd": "Cowden Syndrome", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "9bbcb26b-8965-4d59-b5f8-7484ee2f88bf", "choice_type": "single"} {"question": "non synthetic phase 1 reaction for drug detoxification is", "exp": "Ref-KDT 6/e p24-25", "cop": 4, "opa": "Glucuronidination", "opb": "Acetylation", "opc": "Methylation", "opd": "Oxidation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7506b79e-5875-4b62-8943-1838195c7fb8", "choice_type": "single"} {"question": "Power grip of hand is due to", "exp": "In power grip, the extrinsic muscles provide the major force, the interossei are used as flexors and rotators at the metacarpophalangeal joints, and the thenar muscles are generally active", "cop": 3, "opa": "Palmaris", "opb": "Long flexors", "opc": "Sho flexors", "opd": "Lumbricals", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "674f8bd7-2878-4cb2-b59a-72ea2197f2aa", "choice_type": "single"} {"question": "Hypophysis cerebri is supplied by", "exp": null, "cop": 1, "opa": "Internal carotid artery.", "opb": "External carotid artery.", "opc": "Maxillary artery.", "opd": "Facial artery.", "subject_name": "Anatomy", "topic_name": null, "id": "5bfd57b7-bb5b-4192-b681-4ab329802a71", "choice_type": "single"} {"question": "Commonest intrabronchial cause of haemoptysis is", "exp": "The two most common causes for haemoptysis are bronchitis and bronchiogenic carcinoma. Bronchitis is not provided amongst the options and hence bronchiogenic carcinoma is the single best answer of choice Ref Harrison 19th edition pg 227", "cop": 1, "opa": "Carcinoma lung", "opb": "Adenoma lung", "opc": "Emphysema", "opd": "Bronchiectasis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "69a79c00-a1ae-499f-a849-8b815dc01a0c", "choice_type": "single"} {"question": "Posterior pituitary bodies are", "exp": "(A) Herring bodies ,# An interesting histologic feature of the NEUROHYPOPHYSIS is the presence of Herring bodies.> When viewed with an electron microscope, these are dilated areas or bulges in the terminal portion of axons that contain clusters of neurosecretory granules> The granules contain oxytocin or antidiuretic hormone, along with their associated neurophysins.> Herring bodies often are seen in association with capillaries.> They are somewhat difficult to identify unambiguously by light microscopy; in the image to the right, the label might better say ' probable Herring bodies\".", "cop": 1, "opa": "Herring bodies", "opb": "Brain sand", "opc": "Golgi bodies", "opd": "Amyloid bodies", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "750b8b08-94d1-4c2a-a183-2be2d55a4254", "choice_type": "single"} {"question": "Association of choledocholithiasis in cholithiasis", "exp": "Choledocholithiasis Found in 6-12% of patients with GB stones Retained stones discovered within 2 years of cholecystectomy Recurrent stones detected >2 years of cholecystectomy Ref: Sabiston 20th edition Pgno : 1494", "cop": 2, "opa": "<5%", "opb": "15%", "opc": "20-35%", "opd": "50%", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "30455244-a463-4774-9c57-9d7efe781170", "choice_type": "single"} {"question": "The cold water treatment of burns has a disadvantage of", "exp": "A number of studies have shown that the infection rate is actually increased when patients are immersed in a tub because of the generalized inoculation of burn wounds with bacterial from what was previously a localized infection. Hydrotherapy, on a slant board, is a very useful approach once the wounds are in the process of being debrided and closed. Showering is also effective for wound cleansing in the more stable patient", "cop": 2, "opa": "Vesicle formation", "opb": "Infection", "opc": "Pain", "opd": "Scar formation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6dcd46c5-deda-41a1-8913-20dd8a027a8c", "choice_type": "single"} {"question": "Urothelium is absent in", "exp": "Transitional epithelium: In this type of multilayered epithelium all layers are made up of cuboidal, polygonal or round cells. The cells towards the surface of the epithelium are round. As transitional epithelium is confined to the urinary tract, it is also called urothelium. Location - Transitional epithelium is found in the renal pelvis and calyces, the ureter, the urinary bladder, and pa of the urethra. Because of this distribution it is also called urothelium. REF : Inderbir Singh's Textbook of Human Histology, Seventh edition, pg.no.,39,49.", "cop": 1, "opa": "Renal pelvis", "opb": "Ureter", "opc": "Urinary bladder", "opd": "whole pa of Urethra", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8d662d5c-e249-4993-b54c-00f0201a595b", "choice_type": "single"} {"question": "Caroli's disease is", "exp": "Todani Modification of Alonso-Lej classification Type I - Dilation of extrahepatic biliary tree Type Ia- cystic dilation Type Ib - focal segmental dilation Type Ic- fusiform dilation Type II - Diveicular dilation of extrahepatic biliary tree Type III - Cystic dilation of intra duodenal poion of common bile ducts (choledochocele) Type IVA- Dilation of the extrahepatic and intrahepatic biliary tree Type IVB- Dilation of multiple secretion of extrahepatic bile ducts Type V - Dilation confined to intrahepatic bile ducts (caroli's disease) Type VI - Cystic dilation of cystic duct (not included in Todani's modification) Ref: Sabiston 20th edition Pgno :1510-1511", "cop": 3, "opa": "Type 1 Choledochal cyst", "opb": "Type III Choledochal cyst", "opc": "Type IV Choledochal cyst", "opd": "Type V Choledochal cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "64e6f548-3f48-4b8a-8d6b-c166fbc77d31", "choice_type": "single"} {"question": "Focal lesions of liver is best detected by", "exp": "MRI in liver lesions MRI gas emerged as the best imaging test for liver lesion detection and characterization MRI provides high lesion to liver contrast and does not use radiation Lievr specific contrast media, such as mangifodipir trisodium (taken up by hepatocytes) and ferrumoxides (taken up by kupffer cells) demonstrate selective uptake in the liver and are primarily used for lesion detection These two contrast agents are also useful in characterising specific liver tumors, such as FNH, hepatic adenoma and HCC Ref: Shackelford 7th edition Pg no : 1560, 1571", "cop": 1, "opa": "MRI", "opb": "CT", "opc": "USG", "opd": "PET scan", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "20809d37-676c-4a5c-aca0-dcbcdd14bd52", "choice_type": "single"} {"question": "Lateral ventricle is connected to third ventricle by", "exp": "The lateral ventricle communicates with the third ventricle through interventricular foramen MonroThe foramen of luschka is an apeure through which the lateral recess opens into the subarachnoid space of cerebellopontine angleForamen of magendie is an opening in the roof of 4th ventricle through which its cavity communicates with the subarachnoid space of cerebellomedullary cistern.( Reference: Vishram Singh textbook of clinical neuroanatomy 2nd edition pg -137,121)", "cop": 1, "opa": "Foramen of Monro", "opb": "Foramen of luschka", "opc": "Foramen of magendie", "opd": "Median foramen", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "d0ffe80c-384b-411e-a0d1-db1feb52a69c", "choice_type": "single"} {"question": "Relaxation of mesangial cells of kidney is brought about by", "exp": "Mesangial cells contractionMesangial cells relaxationEndothelinsAngiotensin IIVasopressinNor-epinephrinePlatelet -activation factorPlatelet-derived growth factorThromboxane A2PGF2LT-C4and D4HistamineANPDopaminePGE2cAMP(Refer: Ganong's Review of Medical Physiology 24thedition, pg no: 678-682)", "cop": 3, "opa": "PGF2a", "opb": "Vasopressin", "opc": "cAMP", "opd": "Endothelin", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7001b2d5-e725-47e4-8842-ef2d00ccec36", "choice_type": "single"} {"question": "F20 in ICD 10 denotes", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref. International classification of disorders, 10 th edition", "cop": 2, "opa": "organic disorders", "opb": "substance use disorders", "opc": "mood disorders", "opd": "anxiety disorders", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "23c0ee57-6273-46e0-b313-744078c38622", "choice_type": "single"} {"question": "Content(s) of bicipital groove is/are", "exp": "BICIPITAL GROOVE:-Veical groove between greater and lesser trochanter.Contents:-1. Long head of biceps.2. Ascending branch of anterior circumflex humeral aery.Muscles attachments:/1. Pectoralis major- outer lip2. Teres major- inner lip3. Latissimus dorsi- floor of groove. {Reference: Vishram Singh, pg no.22}", "cop": 2, "opa": "Synol membrane of shoulder jt", "opb": "Ascending branch of anterior circumflex aery", "opc": "Ascending branch of posterior circumflex aery", "opd": "Radial aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "0a4cd0f0-895b-409c-a2e1-b3903205bc0f", "choice_type": "single"} {"question": "Fat embolism is commonly seen in", "exp": "Ref Robbins 8/126; 9/e p128", "cop": 2, "opa": "Head injury", "opb": "Long bone fractures", "opc": "Drowning", "opd": "Hanging", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f41672ab-9180-4c51-9d74-df9745ae28ab", "choice_type": "single"} {"question": "Birbeck's granules in the cytoplasm are seen in", "exp": "ref Robbins 9/e p622 Birbeck granules, also known as Birbeck bodies, are rod shaped or \"tennis-racket\" cytoplasmic organelles with a central linear density and a striated appearance. First described in 1961 (where they were simply termed \"characteristic granules\"), they are solely found in Langerhans cells.", "cop": 1, "opa": "Langerhan's cells", "opb": "Mast cell", "opc": "Myelocytes", "opd": "Thrombocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "49a1c022-831b-4806-9995-cfdf503c0de0", "choice_type": "single"} {"question": "Bacterial endocarditis is most commonly caused by", "exp": "Ref Harrison 19 th ed pg 819 The causative microorganism is primar- ily responsible for the temporal course of endocarditis. b-Hemolytic streptococci, S. aureus, and pneumococci typically result in an acute course, although S. aureus occasionally causes subacute disease. Endocarditis caused by Staphylococcus lugdunensis (a coagulase- negative species) or by enterococci may present acutely. Subacute endocarditis is typically caused by viridans streptococci, enterococci, CoNS, and the HACEK group. Endocarditis caused by Baonella species, T. whipplei, or C. burnetii is exceptionally indolent.", "cop": 3, "opa": "Hemolytic streptococci", "opb": "Streptococcus faecalis", "opc": "Staphylococcus aureus", "opd": "Cardiobacterium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9e8b6d64-c46a-4b4b-99a6-f87cff9b89f2", "choice_type": "single"} {"question": "Secondary ossification centre appears before bih at", "exp": "Long Bone Diaphysis (shaft) - derived from primary ossification center. * present at 6 - 8 weeks of IUL. Epiphysis (ends) - derived from secondary ossification center. * appear after bih Except - Lower end of femur & sometimes upper end of tibia. | Their secondary ossification center appears before bih.", "cop": 2, "opa": "Upper end of femur", "opb": "Lower end of femur", "opc": "Lower end of tibia", "opd": "Lower end of fibula", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "ce147f6e-da7b-436d-891b-6e425a924da4", "choice_type": "single"} {"question": "Autonomous zone of sensory supply by radial nerve", "exp": "Autonomous zone for radial nerve is 1st dorsal web space Refer Campbell 12th/e p 3100", "cop": 1, "opa": "1st dorsal web space", "opb": "Tip of index finger", "opc": "Tip of thumb", "opd": "Tip of little finger", "subject_name": "Anatomy", "topic_name": "Peripheral nerve injuries", "id": "5570ef8c-df54-444c-814f-33ed22de03b0", "choice_type": "single"} {"question": "Sympathetic supply to hea", "exp": "Sympathetic nerves are derived from upper four to five thoracic segments of spinal cord .that is from T1-T4 ganglia. BD CHAURASIS'S HUMAN ANATOMY VOLUME 1. 6TH EDITION.Page no 267.fig.18.30", "cop": 2, "opa": "C5 - C7", "opb": "T1 - T4", "opc": "C1 - C4", "opd": "T5 - T9", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "a174379b-5917-46cd-b04d-5721cd3dff8a", "choice_type": "single"} {"question": "Internal anal sphincter is pa of", "exp": "The internal anal sphincter, IAS, (or sphincter ani internus) is a muscular ring that surrounds about 2.5-4.0 cm of the anal canal; its inferior border is in contact with, but quite separate from, the external anal sphincter. It is about 5 mm thick and is formed by an aggregation of the involuntary circular fibers of the rectum. Its lower border is about 6 mm from the orifice of the anus. Ref - BDC 6e vol2 pg413-416", "cop": 4, "opa": "Internal longitudinal fibres of rectum", "opb": "Puborectalis muscle", "opc": "Deep perineal muscles", "opd": "Internal circular muscle fibres of rectum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fe4287f9-68f7-4578-a457-6a9b01a37ac4", "choice_type": "single"} {"question": "Lumbar plexus is situated in", "exp": "Ans. b (Posterior portion of psoas) (Ref. BDC anatomy Vol. II 3rd ed., 278)LUMBAR PLEXUS# The lumbar plexus lies in the posterior part of the substance of the PSOAS MAJOR muscle.# It is formed by the ventral rami of the upper 4 lumbar nerves.Its branches include:- Ilioinguinal nerve (L1)- Lateral cutaneous nerve of the thigh (L2, L3 dorsal divisions)- Lumbosacral trunk (L4, 5; ventral trunk)- Genitofemoral nerve (L1, L2, ventral divisions)- Obturator nerve (L2, 3, 4; dorsal divisions)- Femoral nerve (L2, 3, 4; dorsal divisions)- Iliohypogastric nerve (L1)Branches of the lumbar plexusNerveSegmentMuscleMotionSensationIliohypogastricT12 -L1# Inter oblique# External oblique# Transversus abdominusAnterior abdominal wall# Inferior abdominal wall# Upper lateral quadrant of buttockIlioinguinalL1Internal obliqueAnterior abdominal wall# Internal medial inguinal ligament# GenitaliaGenitofemoralL1-L2CremasterTesticular# Inferior medial inguinal ligament# Spermatic cordLateral femoral cutaneousL2-L3 # Anterior, lateral and posterior aspect of thighFemoral Nerve1. Anterior division L2-L4# Sartorius,# Pectineus# Medial aspect of lower thigh# Adduction of thigh# Anterior medial skin of thigh2. Posterior division Quadriceps# Knee extension# Patellar movement# Anterior thigh hip and kneeObturator nerve1. Anterior division L2-L4# Gracilis# Adductor longus# Adductor brevis# PectineusThigh adduction# Posterior medial thigh# Medial knee# Hip2. Posterior division # Adductor magnus# Obturator externusThigh adduction with lateral hip rotationKnee", "cop": 2, "opa": "Anterior portion of psoas", "opb": "Posterior portion of psoas", "opc": "Anterior portion of quadratus lumborum", "opd": "Posterior portion of quadratus lumborum", "subject_name": "Anatomy", "topic_name": "Nerves of Abdomen", "id": "f1dd9b27-cff8-4da2-b336-6326410b8094", "choice_type": "single"} {"question": "Child criteria includes", "exp": "Child - Turcotte-pugh(CTP) score CTP score is a measure to assess hepatic function in many liver diseases It was initially devised to classify patients into risk groups prior to undergoing Poo-systemic shunt surgeries It is used to assess prognosis in cirrhosis and many liver disease Divided into 3 classes Class A- 5-6 points( Major surgeries can only be done in this class) Class B - 7-9 points( Only minor surgical procedures can be performed) Class C - 10-15 points (no surgical intervention should be done) Variable 1 point 2 point 3 point Serum albumin >3.5 2.8-3.5 <2.8 Bilirubun(mg/dl) <2 2-3 >3 Prothrombin time or INR <4 <1.7 4-6 1.7-2.3 >6 >2.3 Ascites None Controlled Uncontrolled Enceohalopathy None Controlled Uncontrolled", "cop": 2, "opa": "Nutritional status", "opb": "Serum bilirubin", "opc": "Serum creatinine", "opd": "Acid phosphate", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "053e9672-345c-4540-a86d-19dc10e84344", "choice_type": "single"} {"question": "Hard palate lining contains", "exp": "Palate -Roof of oral cavity Hard palate anteriorly Soft palate posteriorly Hard Palate Anterior fatty zone Posterior glandular zone may have some salivary gland Submucosa - absent in midline raphe of hard palate and gingiva. Palate is covered by a thick oho- keratinised stratified squamous epithelium suppoed densely by collagenous lamina propria Mucosa of the hard palate is bound to underlying bone by relatively dense submucosal tissue with a few accessory salivary glands.", "cop": 2, "opa": "Keratinized mucosa, absent submucosal layer, minor salivary glands", "opb": "Keratinized mucosa, submucosal layer, minor salivary glands", "opc": "Non-keratinized mucosa, submucosal layer, minor salivary glands", "opd": "Non-keratinized mucosa, absent submucosal layer, minor salivary glands", "subject_name": "Anatomy", "topic_name": "NEET 2018", "id": "4262b750-5013-443c-9aac-497cbf2dc726", "choice_type": "single"} {"question": "The parasympathetic secretomotor nerve supply to the nose is", "exp": "The nerve of the pterygoid canal passes through the pterygoid canal to reach the pterygopalatine ganglion. The parasympathetic fibres relay in this ganglion. Postganglion are parasympathetic fibres arising in the ganglion ultimately supply the lacrimal gland and the mucosal glands of the nose, palate, and pharynx. The gustatory or taste fibres do not relay in the ganglion and are distributed to the palate. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Anterior ethmoid nerve", "opb": "Greater palatine nerve", "opc": "Vidian nerve", "opd": "Inferior orbital nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "702f2177-19eb-46fc-a1e4-972372aaadf9", "choice_type": "single"} {"question": "Lift of test is done to assess the function of", "exp": "Refer Campbell's 13th p 2303 The test described in the question is lift off the test which is a test for subsacapularis muscle", "cop": 4, "opa": "Infraspinatus", "opb": "Supraspinatus", "opc": "Teres major", "opd": "Subsacapularis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2fc824d6-1b9a-4132-a8a3-eac9b7b299f7", "choice_type": "single"} {"question": "Polyaeritis nodosa does not involve in", "exp": "Refer robbins 9/e 509/510 Polyaeritis nodosa (PAN), is a systemicnecrotizing inflammation of blood vessels (vasculitis) affecting medium-sized muscular aeries, typically involving the aeries of the kidneys and other internal organs but generally sparing the lungs' circulation. Polyaeritis nodosa may be present in infants. In polyaeritis nodosa, small aneurysms are strung like the beads of a rosary, therefore making \"rosary sign\" an impoant diagnostic feature of the vasculitis. PAN is associated with infection by the hepatitis B or hepatitis Cvirus", "cop": 1, "opa": "Pulmonary aery", "opb": "Bronchial aery", "opc": "renal aery", "opd": "Cerebral aery", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "1f634777-6651-42c7-b7c0-0c65d64046fc", "choice_type": "single"} {"question": "Knudson two hit hypothesis is seen with", "exp": "Ref Robbins 9/e p290 The Knudson hypothesis, also known as the two-hit hypothesis is the hypothesis that most genes require two mutations to cause a phenotypic change. It was first formulated by Alfred G. Knudson retinoblastoma, a tumor of the retina that occurs both as an inherited disease and sporadically. He noted that inherited retinoblastoma occurs at a younger age than the sporadic disease. In addition, the children with inherited retinoblastoma often developed the tumor in both eyes, suggesting an underlying predisposition. Knudson suggested that two \"hits\" to DNA were necessary to cause the cancer. In the children with inherited retinoblastoma, the first mutation in what later came to be identified as the RB1 gene, was inherited, the second one acquired. In non-inherited retinoblastoma, instead two mutations, or \"hits\", had to take place before a tumor could develop, explaining the later onset.", "cop": 2, "opa": "Melanoma", "opb": "Retinoblastoma", "opc": "Ulcerative colitis", "opd": "Crohn disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "90a25099-94c4-46b6-8b71-8ee226189041", "choice_type": "single"} {"question": "Lens is derived from", "exp": "Unlike the rest of the eye, which is derived mostly from the neural ectoderm, the lens is derived from the surface ectoderm. ... As the placode continues to deepen, the opening to the surface ectoderm constricts and the lens cells forms a structure known as the lens vesicle. Latin: lens crystallin Function: Refract light", "cop": 1, "opa": "Ectoderm", "opb": "Endoderm", "opc": "Mesoderm", "opd": "Neuroectoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "71adff46-87a3-486d-943f-007864143dbb", "choice_type": "single"} {"question": "A lesion 3cms away from gastroesophageal junction contain columnar epithelium ,such a type of lesion is", "exp": "Ref Robbins 8/e p10,265,;9/e p271 Metastasis Metastases are secondary implants of a tumor that are dis- continuous with the primary tumor and located in remote tissues (Fig. 5-11). More than any other attribute, the propey of metastasis identifies a neoplasm as malignant. Not all cancers have equivalent ability to metastasize, however. At one extreme are basal cell carcinomas of the skin and most primary tumors of the central nervous system, which are highly invasive locally but rarely metastasize. At the other extreme are osteogenic (bone) sarcomas, which usually have metastasized to the lungs at the time of initial discovery. Approximately 30% of patients with newly diagnosed solid tumors (excluding skin cancers other than melano- mas) present with clinically evident metastases. An additional 20% have occult (hidden) metastases at the time of diagnosis. In general, the more anaplastic and the larger the primary neoplasm, the more likely is metastatic spread, but as with most rules, there are exceptions. Extremely small cancers have been known to metastasize; conversely, some large and ominous-looking lesions may not. Dissemination strongly prejudices, and may preclude, the possibility of curing the disease, so obviously, sho of prevention of cancer, no achievement would confer greater benefit on patients than the prevention of metastases. Malignant neoplasms disseminate by one of three path- ways: (1) seeding within body cavities, (2) lymphatic spread, or (3) hematogenous spread. Spread by seeding occurs when neoplasms invade a natural body cavity. This mode of dissemination is paicularly characteristic of cancers of the ovary, which often cover the peritoneal sur- faces widely. The implants literally may glaze all peritoneal surfaces and yet not invade the underlying tissues. Here is an instance of the ability to reimplant elsewhere that seems to be separable from the capacity to invade. Neoplasms of the central nervous system, such as a medulloblastoma or ependymoma, may penetrate the cerebral ventricles and be carried by the cerebrospinal fluid to reimplant on the men- ingeal surfaces, either within the brain or in the spinal cord. Lymphatic spread is more typical of carcinomas, whereas hematogenous spread is ored by sarcomas. There are numerous interconnections, however, between the lym- phatic and vascular systems, so all forms of cancer may disseminate through either or both systems. The pattern of lymph node involvement depends principally on the site of the primary neoplasm and the natural pathways of local lymphatic drainage. Lung carcinomas arising in the respi- ratory passages metastasize first to the regional bronchial lymph nodes and then to the tracheobronchial and hilar nodes. Carcinoma of the breast usually arises in the upper outer quadrant and first spreads to the axillary nodes. However, medial breast lesions may drain through the chest wall to the nodes along the internal mammary aery. Thereafter, in both instances, the supraclavicular and infra- clavicular nodes may be seeded. In some cases, the cancer cells seem to traverse the lymphatic channels within the immediately proximate nodes to be trapped in subsequent lymph nodes, producing so-called skip metastases. The cells may traverse all of the lymph nodes ultimately to reach the vascular compament by way of the thoracic duct. A \"sentinel lymph node\" is the first regional lymph node that receives lymph flow from a primary tumor. It can be identified by injection of blue dyes or radiolabeled tracers near the primary tumor. Biopsy of sentinel lymph nodes allows determination of the extent of spread of tumor and can be used to plan treatment. Of note, although enlargement of nodes near a primary neoplasm should arouse concern for metastatic spread, it does not always imply cancerous involvement. The necrotic products of the neoplasm and tumor antigens often evoke immunologic responses in the nodes, such as hyperplasia of the follicles (lymphadenitis) and proliferation of macro- phages in the subcapsular sinuses (sinus histiocytosis). Thus, histopathologic verification of tumor within an enlarged lymph node is required. Hematogenous spread is the ored pathway for sarco- mas, but carcinomas use it as well. As might be expected, aeries are penetrated less readily than are veins. With venous invasion, the blood-borne cells follow the venous flow draining the site of the neoplasm, with tumor cells often stopping in the first capillary bed they encounter. Since all poal area drainage flows to the liver, and all caval blood flows to the lungs, the liver and lungs are the most frequently involved secondary sites in hematogenous dissemina- tion. Cancers arising near the veebral column often em- bolize through the paraveebral plexus; this pathway probably is involved in the frequent veebral metastases of carcinomas of the thyroid and prostate. Ceain carcinomas have a propensity to grow within veins. Renal cell carcinoma often invades the renal vein to grow in a snakelike fashion up the inferior vena cava, sometimes reaching the right side of the hea. Hepatocel- lular carcinomas often penetrate poal and hepatic radicles to grow within them into the main venous channels. Remarkably, such intravenous growth may not be accom- panied by widespread dissemination. Many observations suggest that the anatomic localiza- tion of a neoplasm and its venous drainage cannot wholly explain the systemic distributions of metastases. For example, prostatic carcinoma preferentially spreads to bone, bronchogenic carcinomas tend to involve the adre- nals and the brain, and neuroblastomas spread to the liver and bones. Conversely, skeletal muscles, although rich in capillaries, are rarely the site of secondary deposits. The molecular basis of such tissue-specific homing of tumor cells is discussed later on.", "cop": 1, "opa": "Metaplasia", "opb": "Hyperplasia", "opc": "Dysplasia", "opd": "Anaplasia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "71fb8525-77a6-43d4-bc3d-82b39bcae3c7", "choice_type": "single"} {"question": "The most common cause of intestinal obstruction is", "exp": "Adhesions are the most common cause of intestinal obstruction in almost 40% of cases. The clinical manifestation are Intestinal obstruction Abdominal pain Abdominal distension Vomiting and constipation Ref: Bailey and love 27th edition Pg no : 1278", "cop": 1, "opa": "Adhesions", "opb": "Volvulus", "opc": "Intussuception", "opd": "Hernia", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ed013561-23c9-4c63-a70b-dc97e5e1900f", "choice_type": "single"} {"question": "Chloroma is", "exp": ".", "cop": 2, "opa": "Lymphoma", "opb": "Leukemia", "opc": "Sarcoma", "opd": "Carcinoma", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "994d6cae-c0db-4967-9859-0df0fbbb46e0", "choice_type": "single"} {"question": "The term fetal Adenoma is used for", "exp": "Adenomas of the thyroid are typically discrete, solitary masses, derived from follicular epithelium, and hence they are also known as follicular adenomas. Clinically, follicular adenomas can be difficult to distinguish from dominant nodules of follicular hyperplasia or from the less common follicular carcinomas. In general, follicular adeno- mas are not forerunners to carcinomas; neveheless, shared genetic alterations suppo the possibility that at least of subset of follicular carcinomas arises in preexisting adeno- mas (see later). Although the vast majority of adenomas are nonfunctional, a small subset produces thyroid hor- mones and causes clinically apparent thyrotoxicosis. Hormone production in functional adenomas (", "cop": 3, "opa": "Hepatoma liver", "opb": "Fibroadenoma breast", "opc": "Follicular Adenoma of thyroid", "opd": "Craniopharngioma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "18d7d734-372c-4674-8646-c8a3393474a2", "choice_type": "single"} {"question": "Xenophobia is", "exp": "fear of injection- needle phobia Fear of touch- hapnophobia Fear of strangers- xenophobia Fear of animals- zoophobia Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 361", "cop": 3, "opa": "Fear of injection", "opb": "Fear of touch", "opc": "Fear of strangers", "opd": "Fear of animals", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "50d38e3c-e917-417e-acfa-4cab9d71eb24", "choice_type": "single"} {"question": "Posterior to sternum is", "exp": "Posterior to sternum is right ventricle . Ref - medscape.com", "cop": 4, "opa": "Left atrium", "opb": "Left ventricle", "opc": "Right atrium", "opd": "Right ventricle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "c9a55949-0efa-4553-a6ec-d3fa8ba616c2", "choice_type": "single"} {"question": "Absolute lymphocytosis seen in", "exp": ".", "cop": 3, "opa": "SLE", "opb": "Typhoid", "opc": "IMN", "opd": "Brucellosis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "334f4b87-3488-4db0-bd0c-b64b42fdac9f", "choice_type": "single"} {"question": "The cranial nerve passing through cavernous sinus is", "exp": "The cavernous sinuses: drain the venous blood from brain & is placed lateral to the pituitary gland. Contents: Internal carotid aery Abducens nerve (VI) Oculomotor nerve Trochlear nerve Ophthalmic and maxillary division of trigeminal nerve. Mandibular division of trigeminal nerve is not a content of cavernous sinuses.", "cop": 3, "opa": "Optic", "opb": "Olfactory", "opc": "Abducens", "opd": "Facial", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "c1100f61-59b0-4b7a-a587-2c529881e9f1", "choice_type": "single"} {"question": "Chief aery of lateral surface of cerebral hemisphere", "exp": "The chief aery of lateral surface of brain is middle cerebral aeryThe chief aeries of medial and inferior surfaces anterior cerebral aery and posterior cerebral aeries respectively.(Ref: Vishram Singh textbook of clinical neuroanatomy Second Edition page 178)", "cop": 3, "opa": "Anterior cerebral aery", "opb": "Posterior cerebral aery", "opc": "Middle cerebral aery", "opd": "Posterior inferior cerebellar aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "d745c99e-515f-4459-95b1-907cf94fd12e", "choice_type": "single"} {"question": "Treatment of choice for bleeding esophageal and gastric varices", "exp": "Endoscopic Variceal Ligation For control of acute variceal bleeding EVL has been found to be as effective as EST. Technically more difficult than EST in the presence of massive bleed bf due to reduction in filed of view Variceal recurrence rates is higher in EVL since para oesophageal varices (perforating veins) are not obliterated Not suitable for small varices (grade I, II) EVL is associated with lesser complications and rebleeding Variceal eradication in fewer sessions but higher recurrence of varices Ref: Sabiston 20th edition Pgno : 1439", "cop": 2, "opa": "Injection sclerotherapy", "opb": "Banding(Endoscopic)", "opc": "Shunt surgery", "opd": "Devascularization", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "04ffca9e-ddd3-43f0-8a59-495fd6ea8e6b", "choice_type": "single"} {"question": "Internal carotid artery is derivative of", "exp": null, "cop": 2, "opa": "First pharyngeal arch", "opb": "Third pharyngeal arch", "opc": "Fourth pharyngeal arch", "opd": "Sixth pharyngeal arch", "subject_name": "Anatomy", "topic_name": null, "id": "012f16b6-454e-47ea-be80-045e81ea4ba6", "choice_type": "single"} {"question": "Relation of caudate lobe of liver is", "exp": "The caudate lobe of the liver - It is situated on the posterior surface of the liver. Boundaries of caudate lobe of liver - It is bounded on the right - By the groove for the inferior vena cava, on the left - By the fissure for the ligamentum venosum, and inferiorly - By the poa hepatis. Above - It is continuous with the superior surface of liver. Below and to the right, just behind the poa hepatis - It is connected to the right lobe of the liver by the caudate process, Below and to the left - It presents a small rounded elevation called the papillary process Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2 , pg. no. 333", "cop": 3, "opa": "Anterior to right inferior phrenic aery", "opb": "Posterior to poal vein", "opc": "Posterior to ligamentum venosum", "opd": "Posterior to ligamentum teres", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "f98b6a1f-4405-49f8-99f6-d62f5e8f4b9f", "choice_type": "single"} {"question": "Infantile propoion in adult is seen in", "exp": "Normal body propoion in adults Height = arm span Upper segment= lower segment Normal body propoion in infants is Height ( length)> arm span Upper segment> Lower segment. Infantile propoion means increased upper to lower segment ratio. Seen in conditions like Achondroplasia and hypothyroidism. Reverse infantile propoion means increased lower segment. Seen in Eunuchoidism, Marfans syndrome, Homocystinuria, Klinefelter's syndrome. Ref: Nelson's 20th edition, Pg- 3371.", "cop": 2, "opa": "Morquio's disease", "opb": "Achondroplasia", "opc": "Hypothyroidism", "opd": "Malnutrition", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "09fafc9e-5666-4285-9b66-3e65f445da3e", "choice_type": "single"} {"question": "Treatment of choice for asymptomatic pseudocyst pancreas is", "exp": "Treatment of Pancreatic pseudocyst Pseudocyst 5 cm in diameter and <6 weeks old should be observed, as they tend to resolve spontaneously Pseudocyst >5cm diameter is an indications for drainage If infection is suspected, the pseudocyst should be aspirated (not drained) by CT - or US - guided FNA, and the contents examined for organisms by Gran stain and culture If infection is present, and the contents resemble pus, external drainage is employed, using either surgical or percutaneous techniques Pseudocysts communicate with the pancreatic ductal system in upto 80% of cases, so external drainage creates a pathway for pancreatic duct leakage to and through the catheter exit site Methods of internal drainage Percutaneous catheter based methods (transgastruc puncture and stent placement to create a cystogastrostomy) Endoscopic methods (transgastric or Transduodenal puncture and multiple stent placements with or without a nasocystic irrigation catheter) Surgical methods (a true cystoenterostomy, biopsy of cyst wall, evacuation of all debris and contents) Surgical options : Cystogastrostomy, Roux-en-Y cystojejunostomy, cystoduodenostomy Preferred modality : Internal drainage of cyst by cystojejunostomy Ref: Sabiston 20th edition Pgno :1534-1535", "cop": 2, "opa": "Marsupialization", "opb": "Conservative", "opc": "Drainage", "opd": "Cystogastrostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2e8e3318-aae0-49d1-ac3e-2b96e769094a", "choice_type": "single"} {"question": "Uterus is formed by", "exp": null, "cop": 2, "opa": "Urogenital sinus", "opb": "Parameronephric duct", "opc": "Mcronephric duct", "opd": "Mullerian duct", "subject_name": "Anatomy", "topic_name": null, "id": "d6ca702f-f756-46b8-9067-76788f302b46", "choice_type": "single"} {"question": "Vitamin k is required for post translational modification of", "exp": "The role of vitamin K is in the post-translational modification i.e, gcarboxylation of glutamic acid residues in proteins such as : Coagulation factors : Factor II, VII, IX, X Protein C and S Osteocalcin Nephrocalcin Reference: Harpers illustrated biochemistry 30th edition", "cop": 2, "opa": "oxidation", "opb": "carboxylation", "opc": "methylation", "opd": "Hydroxylation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1e08cbc6-df5e-427a-86ad-5c1bebf6364a", "choice_type": "single"} {"question": "BIRADS score 5 is", "exp": "BIRADS score - Breast Imaging Repoing and Data System Category 5- Higly suggestive of malignancy, appropriate action should be taken", "cop": 4, "opa": "Negative", "opb": "Probably benign", "opc": "Suspicious abnormality", "opd": "Highly suggestive of malignancy", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "b07d8c0e-5343-4e10-8945-3f7052f4fd41", "choice_type": "single"} {"question": "While doing thoracocentesis, it is advisable to introduce needle along", "exp": "Thoracocentesis is removal of fluid from space between lung and chest wall.needle is inseed in left 4-5intercostal spaces.needle should be passed upward and posteriorly from xiphocostal angle to reach pericardial cavity. BD CHAURASIA&;S HUMAN ANATOMY VOLUME 1. 6TH EDITION. Page no 300", "cop": 1, "opa": "Upper border of the rib", "opb": "Lower border of the rib", "opc": "In the center of the intercostal space", "opd": "In anterior pa of intercostal space", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "c547c5d5-b5fd-4413-9c59-fa04ef3740ab", "choice_type": "single"} {"question": "Cell mediated immunity is", "exp": "Ref Robbins 8/e p197; 9/e p24 Type hypersensitivity reactions have been given the following names: Immediate type1 hypersensitivity Antibody mediated type 2 hypersensitivity Immune complex mediated or type3 hypersensitivity Cell mediated or type4 hypersensitivity", "cop": 4, "opa": "Type1", "opb": "Type2", "opc": "Type3", "opd": "Type4", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0e73d9df-83cc-483d-a4fd-db10d0e1d1a2", "choice_type": "single"} {"question": "Blood supply of upper pa of vagina", "exp": "The vaginal aery is usually defined as a branch of the internal illiac aery. The vaginal aery can arise from the internal iliac aery or the uterine aery. However, the phrase vaginal branches of uterine aery are the term for blood supply to the vagina coming from the uterine aery. Ref - BDC 6e vol2 pg 394", "cop": 3, "opa": "Middle rectal aery", "opb": "Internal pudendal aery", "opc": "Cervicovaginal branch of uterine aery", "opd": "Superior rectal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c8a2ab49-db14-4158-a1a8-abb1234f6ce2", "choice_type": "single"} {"question": "Vein of Galen drains into", "exp": "The vein of Galen,also known as the great cerebral vein or great vein of Galen is a single median vein.It is formed by union of the two internal cerebral veins.It terminates in the straight sinus.Its tributaries include the basal veins,and veins from the pineal body,the colliculi,the cerebellum,and the adjoining pa of the occipital lobes of the cerebrum. REF.B D Chaurasia's Human Anatomy,Vol 3,Fifth edition,Pg 448", "cop": 3, "opa": "Internal jugular vein", "opb": "External jugular vein", "opc": "Straight sinus", "opd": "Superior sagittal sinus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "4de0b7ea-e294-4b8d-9707-d7dd530df7b0", "choice_type": "single"} {"question": "Apparent volume of distribution of a drug exceeds total body fluid volume, if a drug is", "exp": "Lipid insoluble drugs do not enter cell. Ref-KDT 6/e p18", "cop": 1, "opa": "Sequestrated in body tissues", "opb": "Slowly eliminated from body", "opc": "Poorly soluble in plasma", "opd": "High bound to plasma proteins", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5ec6642c-c2ae-41c1-937f-0a190049e805", "choice_type": "single"} {"question": "The anterior triangle occupy the side of the neck in front of sternomastoid muscle. Each triangle presents boundaries in front", "exp": null, "cop": 1, "opa": "Anterior median line of the neck extending from symphysis menti to supra sternal notch", "opb": "The midline of the neck", "opc": "Midline of the neck upto the sternoclavicular joint", "opd": "Posterior border of thyroid gland", "subject_name": "Anatomy", "topic_name": null, "id": "595b2a57-fc6e-4bc2-80aa-a8c9f6459052", "choice_type": "single"} {"question": "Hassal's corpuscles are seen in", "exp": "Corpuscles of hassall present in the medulla of thymus Formed from eosinophilic epithelial reticular cells arranged concentrically INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY SEVENT EDITION PAGE NO139", "cop": 1, "opa": "Thymus", "opb": "Thyroid", "opc": "Parathyroid", "opd": "Spleen", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "57a57575-091f-48dd-9940-862caf87e7aa", "choice_type": "single"} {"question": "The term physical half life is applicable to", "exp": "Physical half-life is defined as the period of time required to reduce the radioactivity level of a source to exactly one half its original value due solely to radioactive decay. The physical half-life is designated tphys or more commonly t1/2 . Refer 6/e p252", "cop": 3, "opa": "Respiratory preparation", "opb": "Prodrugs", "opc": "Radioactive isotopes", "opd": "Alkylating agents", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "127b285d-18cc-4092-8464-7d335fb78865", "choice_type": "single"} {"question": "The thoracic duct crosses from the right to the left at the level of", "exp": "C i.e. T4 veebrae", "cop": 3, "opa": "T12 veebra", "opb": "T 6 veebra", "opc": "T4 veebra", "opd": "T2 veebra", "subject_name": "Anatomy", "topic_name": null, "id": "bfc879fd-75e6-4298-a2a5-64ec83015779", "choice_type": "single"} {"question": "Sacral promontory is the landmark for", "exp": "The superior hypogastric plexus or the presacral nerve lies in front of the bifurcation of the abdominal aoa and the body of fifth lumbar veebra just below which lies sacral promontery.Origin of inferior mesenteric aery is in front of L3.Origin of superior mesenteric aery is in front of L1.Reference: Textbook of anatomy,Abdomen and Lower limb, Vishram Singh, 2nd editon, page no.162,199,160", "cop": 2, "opa": "Origin of superior mesenteric aery", "opb": "Termination of presacaral nerve", "opc": "Origin of inferior mesenteric aery", "opd": "Origin of Celiac aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "82da5e0a-979b-43dc-943f-57ae74c763c3", "choice_type": "single"} {"question": "Coronary ligament is present between", "exp": "Part of fibrous capsule which is attached to the menisci and lies between menisci and tibial condyle- Coronary ligament.", "cop": 1, "opa": "Menisci and tibial condyle", "opb": "Posterior horns of the two menisci", "opc": "Tibia to meniscus", "opd": "Femur to meniscus", "subject_name": "Anatomy", "topic_name": null, "id": "f2a0dc53-dd9d-4835-9774-7b20d5fe21e8", "choice_type": "single"} {"question": "Bronze diabetes is seen in", "exp": "Refer Robbins page no Pg 9th edition 849 Founately, hemochromatosis can be diagnosed long before irreversible tissue damage has occurred. Screening involves demonstration of very high levels of serum iron and ferritin, exclusion of secondary causes of iron over- load, and liver biopsy if indicated. Screening of family members of probands is impoant. Heterozygotes also accumulate excessive iron, but not to a level that causes significant tissue damage. Currently most patients with hemochromatosis are diagnosed in the subclinical, precir- rhotic stage due to routine serum iron measurements (as pa of other diagnostic workup). Treatment by regular phlebotomy steadily depletes tissue iron stores. With treat- ment, life expectancy is normal.", "cop": 4, "opa": "Wilson's disease", "opb": "Sarcoidosis", "opc": "Lead intoxication", "opd": "Hemochromatosis", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "909a49bb-bcb4-439e-90a7-296e0f8eaf8e", "choice_type": "single"} {"question": "Characterstic feature of compact bones is", "exp": "When we examine a section of compact bone we can see concentric lamellae pervaded by lacunae called haversian system Inderbir Singh&;s textbook of human Histology Seventh edition Pg no94", "cop": 2, "opa": "Volksmann canal", "opb": "Haversian system", "opc": "Lamellar arrangement", "opd": "Trabeculae", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f6d37197-f0da-489d-8e7a-67dd618e2c7b", "choice_type": "single"} {"question": "Inferior vena cava, pierces the central tendon of the diaphragm at the level of", "exp": "A. i.e. (T8 vertebra) (316-BDC-2 4th)INFERIOR VENA CAVA* The IVC is formed by the union of the right and left common iliac veins on the right side of the body of vertebra L5. It ascends in front of the vertebral column on the right side of the aorta, grooves the posterior surface of the liver, pierces the central tendon of the diaphragm at the level of vertebra T8 and opens into the lower and posterior part of the right atrium*** Superior vena cava - begins behind the lower border of the sternal end of the first right costal cartilage, pierces the pericardium opposite the second right costal cartilage and terminates by opening into the upper part of the right atrium behind the third right costal cartilage. It has no valves.", "cop": 1, "opa": "T8 vertebra", "opb": "T10 vertebra", "opc": "T12 vertebra", "opd": "L1 vertebra", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ebd7a660-feab-4392-ae99-c6a04792251e", "choice_type": "single"} {"question": "Half Life of digoxin is", "exp": "Ref-KDT 7/e p55 Digoxin and digitoxin are the main digitalis products. Digoxin is absorbed quickly from the gastrointestinal tract with a bioavailability of between 75% and 95%. It is eliminated primarily through kidneys; therefore, it has a half-life of 36-48 hours in patients who have normal kidney function and 3.5-5 days in patients who are anuric. The reference range for digoxin is as follows: 0.8-2 ng/mL (1.2-2 nmol/L) Half-life: 36 hours Toxic level: more than 2 ng/mL", "cop": 2, "opa": "24hrs", "opb": "40hrs", "opc": "48hrs", "opd": "60hrs", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "7d9b6800-8202-4ff7-8df9-93b861b87fda", "choice_type": "single"} {"question": "Endolymph is secreted by", "exp": "- Vestibule is the central chainberQ. All three semicircular canals (SCCs) form 2/3rd of a circle and are set at right (90deg) anglesQ to each other. 3 SCCs have only 5 openingsQ into the vestibule. Anterior & posterior SCCs are veical and lateral SCC is horizontalQ.Apex of conical modiolus of cochlea (& axis of TM) is directed anterolaterally & inferiorlyQ. Hollow spiral canal around it makes 2.5 (21/2) turnsQ with basal turn having biggest radiusQ.- Endolymph is secreted by secretory cells of stria vascularis of cochleaQ & dark cells in utricle.", "cop": 1, "opa": "Stria vascularis", "opb": "Basilar membrane", "opc": "Cochlear duct", "opd": "Hensen cell", "subject_name": "Anatomy", "topic_name": null, "id": "cf70c668-d65d-4272-b351-409727741010", "choice_type": "single"} {"question": "Punctate basophila are found in", "exp": "Refer robbins 8/e p407 Lead poisoning occurs when lead builds up in the body, often over months or years. Even small amounts of lead can cause serious health problems. Children younger than 6 years are especially vulnerable to lead poisoning, which can severely affect mental and physical development. At very high levels, lead poisoning can be fatal. Symptoms Initially, lead poisoning can be hard to detect -- even people who seem healthy can have high blood levels of lead. Signs and symptoms usually don't appear until dangerous amounts have accumulated. Lead poisoning symptoms in children Signs and symptoms of lead poisoning in children include: Developmental delay Learning difficulties Irritability Loss of appetite Weight loss Sluggishness and fatigue Abdominal pain Vomiting Constipation Hearing loss Seizures Eating things, such as paint chips, that aren't food (pica) Lead poisoning symptoms in newborns Babies exposed to lead before bih might: Be born prematurely Have lower bih weight Have slowed growth Lead poisoning symptoms in adults Although children are primarily at risk, lead poisoning is also dangerous for adults. Signs and symptoms in adults might include: High blood pressure Joint and muscle pain Difficulties with memory or concentration Headache Abdominal pain Mood disorders Reduced sperm count and abnormal sperm Miscarriage, stillbih or premature bih in pregnant women", "cop": 4, "opa": "DDT poisoning", "opb": "Mercury vapour inhalation", "opc": "Cyanide poisoning", "opd": "Lead poisoning", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "85b05495-0f8c-487b-b14d-914f9401ad01", "choice_type": "single"} {"question": "The couinaud's segmental nomenclature is based on the position of the", "exp": "Functional anatomy of the liver is based on couinaud's division of liver into eight (subsequently nine) functional segments, based upon the distribution of poal venous branches and location of hepatic veins in the parenchyma Couinaud 1957", "cop": 1, "opa": "Hepatic veins and poal vein", "opb": "Hepatic veins and biliary ducts", "opc": "Poal vein and biliary ducts", "opd": "Poal vein and hepatic aery", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5fbb31e0-d613-4b22-8769-1886f13b5f35", "choice_type": "single"} {"question": "Most common cause of Cushing syndrome", "exp": "Reference Robbins page no Pg 1125 What are the symptoms of Cushing's syndrome? weight gain. thin arms and legs. a round face. increased fat around the base of the neck. a fatty hump between the shoulders. easy bruising. wide purple stretch marks, mainly on the abdomen, breasts, hips, and under the arms. weak muscles", "cop": 3, "opa": "Pituitary adenoma", "opb": "Adrenal adenoma", "opc": "Exogenous steroids", "opd": "Ectopic ACTH", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "52314e92-df82-48a7-b915-a37cded0a97a", "choice_type": "single"} {"question": "The fusion of two bony structures with a ligament is known as", "exp": null, "cop": 4, "opa": "Synostosis", "opb": "Synchondrosis", "opc": "Diarthrosis", "opd": "Syndesmosis", "subject_name": "Anatomy", "topic_name": null, "id": "3187f5e0-589a-4be8-b564-a1ead85cc443", "choice_type": "single"} {"question": "A major function of the epididymis is", "exp": ".", "cop": 1, "opa": "Storage and transpo of mature sperm", "opb": "Production of testosterone", "opc": "Secretion of estrogens", "opd": "Production of inhibin", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "11498d78-af1b-496a-8c70-24c194c66c70", "choice_type": "single"} {"question": "Race of an individual can be found out by", "exp": "Cephalic index helps to find the race", "cop": 3, "opa": "Ischiopubic index", "opb": "Corporo Basal index", "opc": "Cephalic index", "opd": "Medullary index", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b1025870-6d69-46bc-9817-e8d5c8803c3e", "choice_type": "single"} {"question": "Ramesh 40 yrs make patient presenting with polyuria,pain abdomen,nausea,vomitings,altered sensorium was found to have bronchiogenic carcinoma.the electrolyte abnormality seen in him would be", "exp": "Presence of polyuria, abdominal pain and general Symptoms such as nausea, vomiting,and altered sensorium in a patuent with bronchiogenic carcinoma suggest a diagnosis of hypercalcaemia secondary to paraneoplastic syndrome from PTH related peptide production. Ref Harrison 19th edition pg 313", "cop": 4, "opa": "Hypokalemia", "opb": "Hyperkalemia", "opc": "Hypocalcaemia", "opd": "Hypercalcaemia", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "ca976844-c3b5-4772-a66c-40043eb143f6", "choice_type": "single"} {"question": "Nerve entrapped in pyriformis syndrome is", "exp": "Entrapment of Sciatic nerve by inflamed pyriformis muscle is called as pyriformis syndrome.", "cop": 4, "opa": "Superior gluteal nerve", "opb": "Inferior gluteal nerve", "opc": "Pudendal nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": null, "id": "b637cd13-9746-4e76-8e62-94ec70664892", "choice_type": "single"} {"question": "Parotid duct traverses", "exp": null, "cop": 2, "opa": "Masseter", "opb": "Buccinator", "opc": "Medial Pterygoid", "opd": "Lateral Pterygoid", "subject_name": "Anatomy", "topic_name": null, "id": "9858bd10-a30d-4dc5-bbfa-30ea1e3ad050", "choice_type": "single"} {"question": "Chasaignac tubercle is", "exp": "The anterior tubercle of the sixth cervical veebra is known as the carotid tubercle or Chassaignac tubercle. This separates the carotid aery from the veebral aery and the carotid aery can be massaged against this tubercle to relieve the symptoms of supraventicular tachycardia . The carotid tubercle is also used as a landmark for anasthesia of the brachial plexus and cervical plexus . Ref - pubmed.com", "cop": 2, "opa": "Erbs point", "opb": "Carotid tubercle on C6 veebra", "opc": "Found on 1st rib", "opd": "Medial condyle of humerus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ef828946-5357-49cf-a17a-802b9d9280c6", "choice_type": "single"} {"question": "finger nail hypoplasia is a complication of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential - CLEFT PALATE, FINGER NAIL HYPOLASIA, - SPINA BIFIDA Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 1, "opa": "carbamezipine", "opb": "olanzapine", "opc": "lithium", "opd": "risperidone", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "194c6c06-ad13-49b4-9003-cdc289ef73d9", "choice_type": "single"} {"question": "Serum amyloid associated protein is found in", "exp": "Ref Robbins 9/e p257;8/e 251-252;7/e pg 159 * The AA (amyloid-associated) fibril is a unique nonim- munoglobulin protein derived from a larger (12-kDa)", "cop": 2, "opa": "Alzheimer's disease", "opb": "Chronic inflammatory state", "opc": "Chronic renal failure", "opd": "Malignant hypeension", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b7e37472-6cf2-40fe-bd3d-21b0f8b3acb4", "choice_type": "single"} {"question": "Pyrogenic infection and brain infraction are associated with", "exp": "Ref Robbins 9/e p43 Liquefactive necrosis is seen in focal bacterial or, occasionally, fungal infections, because microbes stimulate the accumulation of inflammatory cells and the enzymes of leukocytes digest (\"liquefy\") the tissue. For obscure reasons, hypoxic death of cells within the central nervous system often evokes liquefactive necrosis (Fig. 1-10). Whatever the pathogenesis, the dead cells are completely digested, transforming the tissue into a liquid viscous mass. Eventually, the digested tissue is removed by phagocytes. If the process was initiated by acute inflammation, as in a bacterial infection, the material is frequently creamy yellow and is called pus", "cop": 2, "opa": "Coagulative necrosis", "opb": "Liquefactive necrosis", "opc": "Caseous necrosis", "opd": "Fat necrosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ac53db85-4903-4044-bf7d-d3b74f64032d", "choice_type": "single"} {"question": "Primary motor area of brain is supplied by", "exp": "Greater pa of lateral surface receives supply from middle cerebral aery, whearas medial surface of cerebrum is majorly supplied by anterior cerebral aery The upper limb and head Are represented on the lateral surface of the coex in homunculus, whereas pelvis and lower limb are on the medial surface of the hemispheres. Therefore the motor and sensory functions of the lower limb are supplied by the anterior cerebral aery while the motor and sensory functions of the upper limb and head are supplied by the middle cerebral aery. Ref: Gray's 39e/p-227", "cop": 3, "opa": "Anterior cerebral aery", "opb": "Middle cerebral aery", "opc": "Anterior and middle cerebral aery", "opd": "Anterior and posterior cerebral aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "a43c22c0-4f40-4f28-ab5d-c88da3a6a025", "choice_type": "single"} {"question": "The structures that pass between middle cerebellar peduncle and pons is", "exp": "Trigeminal nerve exits the brain by a large sensory root and a smaller motor root coming out of the pons at its junction with the middle cerebral peduncle.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg-81, fig 8.9)", "cop": 1, "opa": "Trigeminal nerve", "opb": "Vagus nerve", "opc": "Olfactory nerve", "opd": "Optic nerve", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "ac3a09d0-2b15-447c-a2a3-4138b85703c0", "choice_type": "single"} {"question": "Most anteriorly located valve of the hea is", "exp": ".", "cop": 1, "opa": "Pulmonary", "opb": "Bicuspid", "opc": "Aoic", "opd": "Tricuspid", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "1dce60e5-92e2-43b8-b5b5-68fdac5c1a2a", "choice_type": "single"} {"question": "Vitamin D requirement for children", "exp": "Daily requirement of vitamin D Adults - 100 lU Infants and children - 200 lU Pregnant and lactating- 400 IU", "cop": 2, "opa": "100 IU", "opb": "200 IU", "opc": "300 IU", "opd": "400 IU", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "6e6b4611-02dd-4659-97eb-6f0fc7cf3d40", "choice_type": "single"} {"question": "A 27 year old male presents with low backache that occurs early in the morning assosciated with stiffness, and persists for more than 30 minutes.On examination his chest expansion is also restricted. The most probable diagnosis is", "exp": "Ankylosing spondylitis causes destruction of aicular cailage and bony ankyloeis, especially of the sacroiliac and aprophyseal joints(between tuberosities and processes). It is also known as rheumatoid spondylitis and Mqrir-Strumpell disease.Disease involving sacroiliac joints and veebrae become symptomatic in the second and third affected individuals.", "cop": 4, "opa": "Rheumatoid ahritis", "opb": "Osteoahritis", "opc": "Gouty ahritis", "opd": "Ankylosing spondylitis", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "81cf4da1-2c66-4ad8-9437-9b3f5e6b3c18", "choice_type": "single"} {"question": "Causes of chronic tropical pancreatitis is", "exp": "Tropical (Nutritional) Pancreatitis Associated with mutations of PSTI or SPINK1 gene Protein calorie malnutrition and toxic products of some indigenous foodstuff may contribute to the disease Cassava root contains toxic glycosides, increases susceptibility to free radical injury to pancreas Ref: Sabiston 20th edition Pgno : 1530", "cop": 2, "opa": "Parasitic infection", "opb": "Cassava Ingestion", "opc": "Idiopathic", "opd": "Genetic", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3d424928-fa62-4625-9c1f-46af1cd272b4", "choice_type": "single"} {"question": "Superior relationship of omental foramen is", "exp": "Omental foramen(epiploic foramen, foramen of Winslow ) has following border: anterior: the free border of the lesser omentum, known as the hepatoduodenal ligament. This has two layers and within these layers are the common bile duct, hepatic aery, and hepatic poal vein. posterior: the peritoneum covering the inferior vena cava superior: the peritoneum covering the caudate lobe. of the liver. inferior: the peritoneum covering the commencement of the duodenum and the hepatic aery, the latter passing forward below the foramen before ascending between the two layers of the lesser omentum. left lateral: gastrosplenic ligament and splenorenal ligament. ref - BDC 6e vol2 pg240", "cop": 3, "opa": "Hepatoduodenal ligament", "opb": "Inferior vena cava", "opc": "Caudate lobe of liver", "opd": "1st pa of duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "8c2206d8-f4ef-4b0d-9a38-351e2acf0d52", "choice_type": "single"} {"question": "Bulb of posterior horn of lateral ventricle is formed by", "exp": "Bulb of posterior horn is present on medial wall of posterior horn of lateral ventricle and is formed by fibers of forceps major.", "cop": 3, "opa": "Collateral sulcus", "opb": "calcarine sulcus", "opc": "Forceps major", "opd": "Stria terminalis", "subject_name": "Anatomy", "topic_name": null, "id": "ea3793fe-10da-4e69-af73-2c6b90023af4", "choice_type": "single"} {"question": "Secretomotor fibres of parotid gland passes througha) Auricular temporal nerveb) Lesser petrosal nervec) Deep petrosal nerved) Otic ganglion", "exp": null, "cop": 3, "opa": "acd", "opb": "bcd", "opc": "abd", "opd": "ab", "subject_name": "Anatomy", "topic_name": null, "id": "6f70d2e0-f6e3-4cb7-b560-dd52b4b91444", "choice_type": "single"} {"question": "The action of styloglossus muscle is", "exp": null, "cop": 2, "opa": "Protrusion of tongue", "opb": "Posteriorly retracts the tongue", "opc": "Depression of tongue", "opd": "Elevation of tongue", "subject_name": "Anatomy", "topic_name": null, "id": "c2fbef77-7777-4d5e-9f25-7ad17ba420ad", "choice_type": "single"} {"question": "The prochordal plate marks the site of the future", "exp": "The prochordal plate is a circular, midline thickening of hypoblast cells that are firmly attached to the overlying epiblast cells. The plate will eventually develop into a membrane called the Buccopharyngeal membrane at the site of the future mouth.", "cop": 3, "opa": "Umbilical cord", "opb": "Hea", "opc": "Mouth", "opd": "Anus", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "998de426-ef32-40d5-87be-d5d0a5ba7a77", "choice_type": "single"} {"question": "Total duration of antibiotics in acute osteomyelitis", "exp": "Appropriate antimicrobial therapy 2 weeks intravenous and 4 weeks oral Refer Maheshwari 6th/e p 168", "cop": 3, "opa": "4 weeks", "opb": "2 weeks", "opc": "6weeks", "opd": "8 weeks", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "f2116f3b-4c82-404c-89ae-7eb9f30dbe36", "choice_type": "single"} {"question": "Lower lateral cutaneous nerve of arm is a branch of", "exp": "Lower lateral cutaneous nerve of arm (C5 , C6 ) is a branch of radial nerve given off in the radial groove . It supplies the skin of the lower half of the lateral side of the arm. B D Chaurasia 7th edition Page no : 79", "cop": 1, "opa": "Radial nerve", "opb": "Axillary nerve", "opc": "Median nerve", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "54f82f86-3e65-4a6d-8c3d-526afd042bf8", "choice_type": "single"} {"question": "Veins are an example of", "exp": "the veins are examples of capacitance vessels", "cop": 4, "opa": "Conducting vessels", "opb": "Distributing vessels", "opc": "Resistance vessels", "opd": "Capacitance vessels", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "80f414f0-f187-4298-a8f5-129c734f80e6", "choice_type": "single"} {"question": "Middle ear cavity is formed by pharyngeal pouch", "exp": "Pouch Derivatives 1st Eustachian tube(opens into nasopharynx) and middle ear cavity 2nd Lines tonsillar crypts, forms endodermal epithelium of tonsil 3rd Dorsal - Inferior parathyroid glands Ventral - Thymus 5th fuses with 4th pouch Dorsal - Superior parathyroid glands Ventral - Ultimobranchial body recieves neural crest cells and changes to parafollicular c cells", "cop": 1, "opa": "1", "opb": "2", "opc": "3", "opd": "4", "subject_name": "Anatomy", "topic_name": "Pharyngeal Arches", "id": "2cd67559-4545-471c-a57b-73373b2ca9ca", "choice_type": "single"} {"question": "Growth factor oncogene is", "exp": "Ref Robbins 7/e p182 A number of nuclear transcription factors are the products of oncogene like my,fos, jun myb and rel. Out of these myc is most commonly involved in tumors .SIS oncogene in the only example of a growth factor oncogene in the given options .it's over expression is seen in cancers like astrocytoma and osteosary The other growth factor are described in text", "cop": 3, "opa": "MYC", "opb": "Fos", "opc": "Sis", "opd": "Jun", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "48e989e5-243c-4b64-bb59-d53922831e69", "choice_type": "single"} {"question": "The commonest anatomical position of appendix is", "exp": "A. i.e. Retrocaecal- Vermiform appendix develops from midgut loops, is supplied by appendicular branch of ileocolic aery. It has mesoappendix (mesentery) but no teniaMost common posiion of vermiform appendix is retrocecal (12 o'clock = 65%) followed by pelvic or 4 o'clock positions", "cop": 1, "opa": "Retrocaecal", "opb": "Pelvic", "opc": "Paracaecal", "opd": "Preileal", "subject_name": "Anatomy", "topic_name": null, "id": "802a2c2d-b722-4407-9428-ad7bd43e53e9", "choice_type": "single"} {"question": "Bilateral lymphadenopathy , along with non caseating granulomas is a characteristic feature of", "exp": "Patients are usually evaluated for possible sarcoidosis based on two scenarios .In the first scenario, a patient may undergo biopsy revealing a noncaseating granuloma in either a pulmonary or an extrapulmonary organ. In the second scenario, signs or symptoms suggesting sarcoidosis such as the presence of bilateral adenopathy may be present in an otherwise asymptomatic patient or a patient with uveitis or a rash consistent with sarcoidosis. Ref Harrison 19th edition pg 2205-2206", "cop": 1, "opa": "Sarcoidosis", "opb": "Scleroderma", "opc": "SLE", "opd": "Stein-leventhal syndrome", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "87765e06-a8fc-4deb-beb0-e8a894b20acb", "choice_type": "single"} {"question": "Most common microsomal enzyme involved in metabolism of xenobiotics is", "exp": "Ref Goodman and Gilman 12th/129 CYP 3A4 is involved in metabolism of xenobiotics", "cop": 1, "opa": "CYP 3A4", "opb": "CYP 1A2", "opc": "CYP 2A6", "opd": "CYP 2B6", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "013e1a77-553c-42f8-b7ae-d5fb307700ee", "choice_type": "single"} {"question": "Raised LDH levels in aqueous is seen in", "exp": "All the three enzymes: LDH(lactose dehydrogenase) NSE(neuron specific enolase) PGI(phosphoglucoisemerase) Are raised in patients of Retinoblastoma Refer khurana 6/e p 303", "cop": 4, "opa": "Galctosemia", "opb": "Glaucoma", "opc": "Hemangioblastoma", "opd": "Retinoblastoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fd42f404-4036-4be7-bf91-4c7a232a237c", "choice_type": "single"} {"question": "NOT a Spiral muscle among the following is", "exp": "Spiral muscle are\n\nSupinator\nPectoralis major\nTrapezius\nLatissimus dorsi", "cop": 1, "opa": "Sternocleidomastoid", "opb": "Supinator", "opc": "Pectoralis major", "opd": "Trapezius", "subject_name": "Anatomy", "topic_name": null, "id": "6c1a6858-ca94-4de2-b6ce-50d579a1db35", "choice_type": "single"} {"question": "Nerve supply of kidney is from", "exp": "Celiac plexus is formed by the greater and lesser splanchnic nerves of both sides, and fibers from the anterior and posterior vagal trunks. Contribute to renal plexus ref - sciencedirect.com", "cop": 2, "opa": "Lumbar plexus", "opb": "Coeliac plexus", "opc": "Inferior mesentric nerve", "opd": "Hypogastric plexus", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "78f5d5e6-13d1-47c2-a903-042f00df88c4", "choice_type": "single"} {"question": "Interpeduncular fossa contains", "exp": "Contents of interpeduncular fossa are  \n\n Infundibulum\n Mammillary bodies\n Oculomotor nerve\n Posterior perforating substance.", "cop": 2, "opa": "Mammillary bodies, pineal gland, oculomotor nerve, infundibulum", "opb": "Oculomotor nerve, mammillary bodies, infundibulum, posterior perforating substance", "opc": "Tuber cinerium, mammillary bodies, oculomotor nerve, anterior perforating substance", "opd": "Oculomotor nerve, mammillary bodies, optic chiasma, anterior perforating substance", "subject_name": "Anatomy", "topic_name": null, "id": "c6207160-fa93-4dd5-b0a0-1b279e13fe46", "choice_type": "single"} {"question": "Posterior communicating aery a branch of", "exp": "Posterior communicating aery is a branch of internal carotid which connects posterior cerebral aery Ref: Gray's 40e/p-250-251", "cop": 1, "opa": "Internal carotid", "opb": "External carotid", "opc": "Middle cerebral", "opd": "Posterior superior cerebellar", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6f35286a-7bb6-41a3-8e98-2e9ee9ad5e54", "choice_type": "single"} {"question": "Meconium peritonitis occurs", "exp": "Meconium Peritonitis Meconium is a sterile mixture of epithelial cells, mucin, salts, fats and bile and is formed when the fetus commences to swallow amniotic fluid. Meconium peritonitis is due to intestinal perforation mostly the result of some form of neonatal intestinal obstruction (eg. meconium ileus in cystic fibrosis patients). When meconium enters the peritoneal cavity, an exudate is secreted that organizes rapidly, matting of intestinal loops occur, and in many cases in a matter of weeks, the extruded becomes calcified. Meconium remains sterile until about 3 hrs after bih; thereafter, unless the perforation has become sealed, sterile meconium peritonitis gives place to acute bacterial peritonitis which unless treated promptly is rapidly fatal. The clinical picture may be that of peritonitis and/or intestinal obstruction. Meconium peritonitis should always be suspected when a baby is born with a tense abdomen, who is vomiting and in whom there is a failure to discharge meconium. Treatment Prognosis is poor but recovery may follow prompt operation. Treatment consists of elimination of intestinal obstruction, closure of perforation and drainage of the peritoneal cavity. Ref : Bailey & Love 24/e, p 1141", "cop": 3, "opa": "Before bih", "opb": "After bih", "opc": "Before and after bih", "opd": "Due to trauma during bih", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f7afb73e-e17a-4df3-a931-de38d0250942", "choice_type": "single"} {"question": "Erb's palsy occurs due to involvement of", "exp": "ERB'S PARALYSIS:- upper plexus injury.Caused by forceful widening of the angle between the head and shoulder which may occur by traction of arm during the bih of a child or by fall on the shoulder.Involves upper trunk - C5, C6 roots. Leads to typical deformity in the limb- policeman's tip hand/ poer's tip hand. The arm hangs by the side,adducted and medially rotated, forearm is extended and pronated. 1. Adduction of arm due to deltoid paralysis.2. Medial rotation of arm-paralysis of supraspinatus, infraspinatus and teres minor.3. Extension of elbow- paralysis of biceps brachii4. Pronation of forearm- paralysis of biceps brachi5. Loss of sensation over outer aspect of arm due to C6 spinal nerve involvement.{Reference: vishram singh, page no. 62}", "cop": 1, "opa": "Upper trunk of brachial plexus", "opb": "Middle trunk of brachial plexus", "opc": "Medial cord of brachial plexus", "opd": "Lateral trunk of brachial plexus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "627fc0b4-f4c3-4c5d-b498-f94c11d3fc62", "choice_type": "single"} {"question": "The upper lip is derived from", "exp": "The upper lip is formed by the fusion of two maxillary prominences with the two medial nasal prominences Ref : Langman's Medical Embryology 14e pg 295,298.", "cop": 2, "opa": "Maxillary prominence and mandibular prominence", "opb": "Maxillary prominence and medial nasal prominence", "opc": "Maxillary prominence and lateral nasal prominence", "opd": "Mandibular prominence and medial nasal prominence", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "87f84d04-bb0d-49d7-a780-27fe106e7ee9", "choice_type": "single"} {"question": "Duval procedure in case of chronic pancreatitis involves", "exp": "Surgical procedures in chronic pancreatitis Drainage procedure Duval procedure : Distal pancreatictomy with Roux-en-Y pancteaticojejunostomy (caudal PJ) Ref: Sabiston 20th edition Pgno : 1535", "cop": 1, "opa": "Distal resection of tail of pancreas with end to end pancteaticojejunostomy", "opb": "Distal resection of tail of pancreas with longitudinal opening of duct and pancteaticojejunostomy", "opc": "Duodenum preserving pancreatic head resection", "opd": "Local section of pancreatic head with longitudinal pancteaticojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ac44751d-b56e-4c54-a4cd-bc64abc2262f", "choice_type": "single"} {"question": "First primary ossification centre to appear of carpal bones is", "exp": "(A) Capitate # Appearance of Capitate slightly earlier than Hamate, the 3rd carpal which showed its appearance at the age of 3 :o 5 years was Triquetral.> Trapezium, trapezoid and Scaphoid ossified between the ages of 5 to 9 year's in both the sexes", "cop": 1, "opa": "Capitate", "opb": "Scapoid", "opc": "Triquitral", "opd": "Pisiform", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "9a4cd983-b5a8-420d-9620-6be724c8b739", "choice_type": "single"} {"question": "Duschenne dystrophy is a", "exp": "duchennes Dystrophy is progressive waeknessof gene muscles Dystrophin gene defects Unable to walk after age 13 Progressive. Kyphoscliosis Respiratory failure in 2nd or 3rd decade Refer Robbins 7th/1336", "cop": 4, "opa": "Autosomal dominant disorder", "opb": "X-linked dominant disease", "opc": "Autosomal recessive diseases", "opd": "X linked recessive disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2831c009-9efa-4f52-854a-cb4c265d8b33", "choice_type": "single"} {"question": "Cholangiocarcinoma has been associated with infection by", "exp": "Risk factors for cholangiocarcinoma Choledochal cyst Primary sclerosing cholangitis Ulcerative colitis. RPC or hepatolithiasis. Biliary enteric anastomosis HBV, HIV, HCV Choledocholithiasis Clonorchis sinensis and opisthorchis viverrini Cirrhosis Radon Asbestos, Nitrosamines, Dioxib(AND). Diabetes, Obesity, OCP's, smoking, Thorotrast, Isoniazid(DOSTI) Ref: Sabiston 20th edition Pgno :1514", "cop": 2, "opa": "Paragonimus westermani", "opb": "Clonorchis sinensis", "opc": "Loa Loa", "opd": "Schistosoma haematobium", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ea4408f6-0021-4a99-9d34-e448eeed52d0", "choice_type": "single"} {"question": "Mental spines provide attachment to", "exp": "Mental spine also known as genial tubercle, is a small bony elevation found on the inner surface of mandible, in the midline.\nThere are 4 mental spines - superior and inferior pair.\n\n\nSuperior genial tubercle gives origin to genioglossus muscle of tongue.\nInferior genial tubercle gives origin to geniohyoid muscle.", "cop": 1, "opa": "Genioglossus", "opb": "Anterior & posterior bellies of digastric", "opc": "Mylohyoid", "opd": "Superior constrictor of pharynx", "subject_name": "Anatomy", "topic_name": null, "id": "78edde3b-3420-444b-8ad6-bd6d5ce5a745", "choice_type": "single"} {"question": "Ca urinary bladder commonly presents as", "exp": "Painless haematuria is by far the most common symptom and should be regarded as indicative of a bladder carcinoma untill proven otherwise.\" MC primary tumor which gives secondary to penis - bladder carcinoma Commonest tumor of Urinary bladder - transitional cell Ca Commonest tumor of U.B. in a child - rhabdomyosarcoma MC symptom of renal cell Ca - painless hematuria MC symptom of wilm's tumor - mass in abd. MC symptom of bony metastasis - pain MC symptom of renal stone - pain Earliest symptom of vesical calculus - Frequency Cardinal symptom of renal trauma - Hematuria MC symptom of acute aerial occlusion - pain Ref : Bailey & Love 25/e p1336", "cop": 2, "opa": "Dysuria", "opb": "Hematuria", "opc": "Frequency", "opd": "Abdominal lump", "subject_name": "Anatomy", "topic_name": "Urology", "id": "bee9bc93-b8c7-426b-ac24-c8cd0d49e0ff", "choice_type": "single"} {"question": "Deletion of the sho arm of chromosome 11 is seen in", "exp": "Ref Robbins 8/e p479-480, 9/e pPathogenesis and Genetics. The risk of Wilms tumor is increased with at least three recognizable groups of congenital malformations associated with distinct chromosomal loci. Although Wilms tumors arising in this setting account for no more than 10% of cases, these syndromic tumors have provided impoant insight into the biology of this neoplasm. * The first group of patients has the WAGR syndrome, characterized by Wilms tumor, aniridia, genital anoma-lies, and mental retardation. Their lifetime risk of developing Wilms tumor is approximately 33%. Individuals with WAGR syndrome carry constitutional (germline) deletions of 11p13. Studies on these patients led to the identification of the first Wilms tumor-associated gene, WT1, and a contiguously deleted autosomal dominant gene for aniridia, PAX6, both located on chromosome 11p13. Patients with deletions restricted to PAX6, with normal WT1 function, develop sporadic aniridia, but they are not at increased risk for Wilms tumors.9 479-480", "cop": 3, "opa": "Osteosarcoma", "opb": "Meningiomaa", "opc": "Wilms tumor", "opd": "Colon carcinoma", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "32cea552-46a4-4832-a04e-89afa3c87fc4", "choice_type": "single"} {"question": "Most common cause of hematocolpos", "exp": "Hematocolpos is collection of blood in the vagina. Which means the level of obstruction should be at or below the hymen. Cervical atresia will result In hematometra. The commonest cause is imperforate hymen followed by low transverse vaginal septum. The complications include hematometra, hematosalpinx, endometriosis and infeility.", "cop": 4, "opa": "Cervical atresia", "opb": "Vaginal atresia", "opc": "Transverse vaginal septum", "opd": "Imperforate hymen", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e89d6f41-8b6d-4810-b62e-787d73749978", "choice_type": "single"} {"question": "An 18yr old male presents with a draining sinus on his left leg with pus discharge and discharge of bony pieces since 3 months. the diagnosis is", "exp": "Chronic osteomyelitis is the most common complication of acute osteomyelitis. If infection persists, pus and tiny sequestrated spicules of bone may continue to discharge through perforation in involucrum(cloacae). The hallmark of chronic osteomyelitis is infected dead bone within a compromised soft-tissue envelope. The infected foci within the bone are surrounded by sclerotic, relatively avascular bone covered by a thickened periosteum and scarred muscle and subcutaneous tissue. This avascular envelope of scar tissue leaves systemic antibiotics essentially ineffective. * Secondary infections are common, and sinus track cultures usually do not correlate with cultures obtained at bone biopsy. * Multiple organisms may grow from cultures taken from sinus tracks and from open biopsy specimens of surrounding soft tissue and bone. symptoms Pain, swelling. Discharging sinus. Bone thickening. Deformity. Joint stiffness. Shoening of limb, Pathological fracture. Sinus track malignancy. ref : maheswari 9th ed", "cop": 1, "opa": "Chronic osteomyelitis", "opb": "Ewings sarcoma", "opc": "Osteoid osteoma", "opd": "Cellulitis", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "1c0c4ffc-325a-4b7d-9f22-6e9d59c8f075", "choice_type": "single"} {"question": "In case of IVD with transverse are, following can be done", "exp": "Management of transverse lie and IUD is done best by ceserean section and others like evisceration and decapitation", "cop": 3, "opa": "Decapitation", "opb": "Evisceration", "opc": "Craniotomy", "opd": "Cesarean section", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "cbb55e3a-4f7d-4685-bc7e-f32ffae14d00", "choice_type": "single"} {"question": "'Boiled lobster' skin appearance seen in", "exp": "Boric acid dermal: Generalised erythema creating a 'boiled lobster' appearance. There is massive desquamation which is indistinguishable from epidermal necrolysis or staphylococcal scalded skin syndrome in neonates. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 416", "cop": 2, "opa": "Acetic acid poisoning", "opb": "Boric acid poisoning", "opc": "Alkali poisoning", "opd": "Carbolic acid poisoning", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5e481669-e33e-4b0a-90bb-554900aba4e3", "choice_type": "single"} {"question": "Most stable position of ankle is", "exp": "DORSIFLEXION FOOT:- The forefoot is raised, and the angle between the front of the leg and the dorsum of the foot is diminished.The wider anterior trochlear surface of the talus fits into the lower end of narrow posterior pa of the lower end of tibia.No chance of dislocation in dorsiflexion. PLANTAR FLEXION OF FOOT:-Forefoot is depressed and the angle between leg and foot is increased.The narrow posterior pa of trochlear surface of talus loosely fits into the wider anterior pa of lower end of tibia.High heels causes plantar flexion of ankle joint and its dislocation. Eversion: movement in which the lateral border of the foot is elevated so that the sole faces laterally. Inversion: movement in which the medial border of the foot is elevated so that the sole faces medially. In eversion and inversion, the entire pa of the foot below the talus moves together. Inversion is accompanied by plantar flexion of the foot and adduction of the forefoot.Eversion is accompanied by the dorsiflexion of the foot and adduction of the forefoot. JOINTS TAKING PA:-Subtalar Talocalcaneonavicular Transverse talar AXIS:-These movements takes place around an oblique axis which runs forwards, upwards and medially, passing from the back of the calcaneum, through sinus tarsi,to emerge at the superomedial aspect of the neck of the talus.The obliquity of the axis pay accounts for the adduction, abduction, plantar flexion and dorsiflexion which are associated with these movements. RANGE:-Inversion is more free than eversion The range of movements is increased in plantar flexion. Ref - BDC 6e vol 2 pg 150", "cop": 2, "opa": "In plantar flexion", "opb": "In dorsiflexion", "opc": "In inversion", "opd": "In eversion", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d945a568-8d49-462e-b4a2-6ae8af04e5cd", "choice_type": "single"} {"question": "Commonest acute presentation of sickle cell anemia is", "exp": "Ref Harrison 19 th ed pg 634 abnormalities provoke unpredictable episodes of microvascular vasoocclusion and premature RBC destruction (hemolytic anemia). Hemolysis occurs because the spleen destroys the abnormal RBC. The rigid adherent cells clog small capillaries and venules, causing tissue ischemia, acute pain, and gradual end-organ damage. This venooc- clusive component usually dominates the clinical course. Prominent manifestations include episodes of ischemic pain (i.e., painful crises) and ischemic malfunction or frank infarction in the spleen, central nervous system, bones, joints, liver, kidneys, and lungs", "cop": 2, "opa": "Priapism", "opb": "Bone pain", "opc": "Fever", "opd": "Splenomegaly", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "bd0e9027-8168-41f6-a832-3f27b17f0097", "choice_type": "single"} {"question": "Embryo proper is derived from", "exp": "Outer cell mass forms trophoblast.\nInner cell mass forms embryoblast.", "cop": 2, "opa": "Cytotrophoblast", "opb": "Inner cell mass", "opc": "Syncytotrophoblast", "opd": "Amniogenic cells", "subject_name": "Anatomy", "topic_name": null, "id": "68ff4b1f-6f1d-44e4-a0f7-3cb14880b606", "choice_type": "single"} {"question": "Area that lies immediately lateral to the anterior perforating substance is.", "exp": "Limen insula lies immediately lateral to substantia perforate anterior (i.e. anterior perforating substance).", "cop": 4, "opa": "Orbital gyrus", "opb": "Uncus", "opc": "Optic Chiasma", "opd": "Limen Insulae", "subject_name": "Anatomy", "topic_name": null, "id": "f8dda1ca-be87-4e7f-9b80-7b8e5301c8e1", "choice_type": "single"} {"question": "Diencephalon represents", "exp": "The diencephalon is the pa of brain between the cerebrum and brainstem.The cavity within it is called third ventricleThe pas of diencephalon are:ThalamusMetathalamusEpithalamusSubthalamusHypothalamus(Ref: Vishram Singh textbook of clinical neuroanatomy Second Edition pg -123)", "cop": 2, "opa": "Lateral ventricle", "opb": "3rd ventricle", "opc": "4th ventricle", "opd": "Aquedct", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "656534f0-7618-43c9-9843-e568777cf009", "choice_type": "single"} {"question": "Primary auditory area is", "exp": "The cerebrum is the largest pa of the brain and consists of two cerebral hemispheres connected corpus callosum. The surface layer of each hemisphere is called the coex and is composed of gray matter.The frontal lobe is situated in front of the central sulcus and above the lateral sulcus.The parietal lobe is situated behind the central sulcus and above the lateral sulcus.The precentral gyrus lies immediately anterior to the central sulcus and is known as the motor area and control voluntary movements on the opposite side of the body.Most nerve fibers cross over to the opposite side in the medulla oblongata as they descend to the spinal cord. The postcentral gyrus lies immediately posterior to the central sulcus and is known as the sensory areaThe superior temporal gyrus lies immediately below the lateral sulcus. The middle of this gyrus is concerned with the reception and interpretation of sound and is known as the auditory area.Broca's area, or the motor speech area, lies just above the lateral sulcus. The visual area is situated on the posterior pole and medial aspect of the cerebral hemisphere in the region of the calcarine sulcus. It is the receiving area for visual impressions.", "cop": 3, "opa": "Inferior temporal gyrus", "opb": "Occiptal coex", "opc": "Superior temporal gyrus", "opd": "Frontal coex", "subject_name": "Anatomy", "topic_name": null, "id": "2f4e3344-642c-4c72-8dac-cf01d5a3a46f", "choice_type": "single"} {"question": "Superficial epigastric aery is a branch of", "exp": "branches of femoral aery - In the femoral triangle, it gives off six branches, three superficial and three deep. The superficial branches are the superficial external pudendal, the superficial epigastric and the superficial circumflex iliac. The deep branches are the profunda femoris, the deep external pudendal and muscular branches. Ref : B D Chaurasi's Human Anatomy , seventh edition , volume 2 , pg. no., 48", "cop": 4, "opa": "Internal pudendal aery", "opb": "External pudendal aery", "opc": "Internal iliac aery", "opd": "Femoral aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "86e3e1af-53d3-441b-b3d3-dc050c3e60a3", "choice_type": "single"} {"question": "Epsilon wave is seen in", "exp": ".", "cop": 4, "opa": "Hypothermia", "opb": "WPW syndrome", "opc": "Brugada syndrome", "opd": "Arrhythmogenic right ventricular dysplasia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e01aa7ed-8807-462d-bd1d-fb5f0e52f6af", "choice_type": "single"} {"question": "Mental foramen is located near", "exp": "On the medial surface of the mandible is the mandibular foramen for inferior alveolar nerve and vessels. The foramen leads in to mandibular-canal which opens on the lateral surface of the mandible at mental foramen, situated below the second premolar tooth.\nFracture of mandible most commonly involves neck.", "cop": 1, "opa": "First premolar of mandible", "opb": "Second molar of mandible", "opc": "Canine of mandible", "opd": "Canine of maxilla", "subject_name": "Anatomy", "topic_name": null, "id": "9f1ac890-55f0-4a59-8305-062f1da5439c", "choice_type": "single"} {"question": "Treatment of choice for extrahepatic poal thrombosis", "exp": "Since obstruction is in the poal vein, to bypass the obstruction the shunt should be preferably REX shunt (mesenteric-left poal shunt) Splenorenal shunt is also done in EHPVO but in 50% of patients of EPHVO, splenic vein is thrombosed, not available for splenorenal shunt", "cop": 1, "opa": "Mesocaval shunt", "opb": "Poocaval shunt", "opc": "Mesorenal shunt", "opd": "Splenorenal shunt", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ac62e684-2cb0-449a-90f1-34bef5bf8a69", "choice_type": "single"} {"question": "In Apoptosis ,cytochrome C acts through", "exp": "Ref Robbins 8/e p29; 9/e p55 APAF1 (Apoptotic Peptidase Activating Factor 1) is a Protein Coding gene. Diseases associated with APAF1 include Dystrophinopathies and Lung Cancer. Among its related pathways are ApoptosisModulation and Signaling and TP53 Regulates Transcription of Cell Death Genes.", "cop": 1, "opa": "Apaf1", "opb": "Bcl_2", "opc": "FADD", "opd": "TNF", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "aa7e7239-8cff-4a21-a0ed-5fc4fe1d3daf", "choice_type": "single"} {"question": "Graham Cole test refers to", "exp": "Oral cholecystography (Graham Cole Test) Once considered the diagnostic test of choice for gallstones, oral cholecystography has been replaced by ultrasonography It involves oral administration of a Radiopaque compound that is absorbed, excreted by the liver, and passed into the gallbladder Successful visualisation of GB in oral cholecystography depends on Blood flow to liver Ability of the liver cells to excrete dye into the bile (functioning liver) Patency of hepatic and cystic duct system Ability of GB to concentrate to excreted dye (by absorbing water) Ref: schwaz's principle of surgery 10th edition Pgno : 1141", "cop": 1, "opa": "Oral cholecystography", "opb": "Intravenous cholangiography", "opc": "Pre operative cholangiography", "opd": "Post operative cholangiography", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "c60a5450-bafb-45ff-a9c7-c556fdb91c13", "choice_type": "single"} {"question": "First cell in RBC development is", "exp": ".", "cop": 1, "opa": "Proerythroblast", "opb": "Intermediate normoblast", "opc": "Reticulocyte", "opd": "Basophilic erythroblast", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "30a41374-7029-4b43-8833-a79c01534c00", "choice_type": "single"} {"question": "NOT a hybrid muscle among the following is", "exp": "Nerve supply of above muscles-\nBrachialis\n\nMusculocutaneous Nerve and Radial nerve (proprioception)\n\nFlexor pollicis brevis\n\nSuperficial head by Median Nerve\nDeep head by Ulnar nerve\n\nSternocleidomastoid\n\nSpinal accessory nerve and C3 , C4\n\nAdductor pollicis\n\nUlnar nerve", "cop": 4, "opa": "Brachialis", "opb": "Flexor pollicis brevis", "opc": "Sternocleidomastoid", "opd": "Adductor pollicis", "subject_name": "Anatomy", "topic_name": null, "id": "16bdde93-a536-4051-a484-4901a4b97dcd", "choice_type": "single"} {"question": "Reffered pain to Inferior angle of right scapula in acute cholecystitis is known as", "exp": "It is seen in acute cholecystitis Boa's sign - Hyperaesthesia below the right scapula Murphy's sign- Inspiratory arrest with deep palpation in the RUQ in acute cholecystitis (also known as Naunyn's sign) Cullen's Sign- Periumbilical ecchymosis. Seen in retro peritoneal bleeding associated with severe Pancreatitis Ref: Sabiston 20th edition Pgno : 1526, 1494", "cop": 3, "opa": "Murphy's sign", "opb": "Naunyn's sign", "opc": "Boa's sign", "opd": "Cullen's sign", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "825a0237-5f25-4aca-9791-1e8921316b01", "choice_type": "single"} {"question": "Nerve involved in Foot drop", "exp": "The deep peroneal nerve is the nerve of the anterior compament of the leg and the dorsum of the foot. It is a terminal branch of common peroneal nerve. Its muscular branches are1. Muscles of the anterior compament of the leg; These include: (i) Tibialis anterior, (ii) Extensor hallucis longus. (iii) Extensor digitorum longus, and (iv) Peroneus Teius.2. The extensor digitorum brevis (on the dorsum of the foot), is supplied by the lateral terminal branch of the deep peroneal nerveParalysis of muscles of the anterior compament of the leg results in loss of the power of dorsiflexion of the foot. As a result, the foot is plantar flexed. The condition is called as \"foot drop\".Reference: Chaurasia Volume II; 7th edition; Page no: 105", "cop": 1, "opa": "Deep Peroneal Nerve", "opb": "Superficial Peroneal Nerve", "opc": "Superficial Peroneal Nerve", "opd": "Tibial pa of Sciatic Nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "f3036ce4-20e3-4905-a610-e9cd0e2d6fc1", "choice_type": "single"} {"question": "An influenza is treated by", "exp": "Refer KDT 6th/777,778 Oseltamivir and zanamivir are used for An influenza", "cop": 4, "opa": "Amantidine", "opb": "Ribavarin", "opc": "Cidofovir", "opd": "Oseltamivir", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7a54e426-29d8-4525-8a20-965efb322ab3", "choice_type": "single"} {"question": "Most common tumour of hea is", "exp": "Ref Harrison 19 th ed pg 1577: 289e-1 Myxomas are the most common type of primary cardiac tumor in adults, accounting for one-third to one-half of all cases at postmoem examination, and about three-quaers of the tumors treated surgically. They occur at all ages, most commonly in the third through sixth decades, with a female predilection. Approximately 90% of myxomas are sporadic; the remainder are familial with autosomal dominant transmission.", "cop": 1, "opa": "Myxoma", "opb": "Rhabdomyosarcoma", "opc": "Fibroma", "opd": "Leiomyosarcoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cda07779-bb95-4a26-ba20-525366b03439", "choice_type": "single"} {"question": "Choledochal cyst", "exp": "Carcinoma in Choledochal cyst More than half tumors occur within the cyst itself(intracystic) and may recur after cyst excision Risk of malignancy is decreased after cyst excision, but risk persist even after cyst excision Type I and IV cysts have highest risk of cancer When present most commonly seen along posterior cyst wall If is age related Ref: Sabiston 20th edition Pgno :1511", "cop": 4, "opa": "Mostly present in adulthood", "opb": "Excision is infrequently done", "opc": "Presents as slowly progressive jaundice", "opd": "Can lead to carcinoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d6f5dac3-f921-4993-8858-642331276b34", "choice_type": "single"} {"question": "Right tracheobronchial angle is", "exp": "Right tracheobronchial angle is 25-30 degree . Ref - Researvhgate.net", "cop": 2, "opa": "10- 15 Degree", "opb": "25-30 Degree", "opc": "40-50 Degree", "opd": "80-90 Degree", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "29262ba9-50cc-4de4-b16d-a3acb1c18099", "choice_type": "single"} {"question": "Endochondral ossification is seen in", "exp": "Long bones and medial end of clavicle bone develop by endochondral ossification Flat bones of skull; facial skeleton; mandible and lateral end of clavicle develop by intramembranous ossification. Ref: Gray's39e/p185-210", "cop": 1, "opa": "Clavicle", "opb": "Mandible", "opc": "Nasal bones", "opd": "Flat bones of skull", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "39178e0d-5e46-40dc-b646-411cd5e19f93", "choice_type": "single"} {"question": "Sump syndrome occurs most commonly after", "exp": "SUMP SYNDROME Paiculate matter, stones and food debris accumulate and stagnate in the distal, \"blind\" end of the common duct SUMP syndrome occurs after choledochoduodenostomy Occasional cause of recurrent cholangitis that can result in anastomotic stricture Management Endoscopic management, consisting of sphincterectomy with or without balloon dilation of the anastomosis End - to-side hepatic jejunostomy, Roux-en-Y, to prevent persistent regurgitation of intestinal contents and to remove the \"sump\" permenantly, is preferred surgical procedure Ref: Blumga 5th edition Pgno :632", "cop": 2, "opa": "Cholecystojejunostomy", "opb": "Choledochoduodenostomy", "opc": "Mirriz's syndrome", "opd": "Choledochojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "133bd8a9-0cd8-4ca3-802c-4b19c7c40e87", "choice_type": "single"} {"question": "Geniculate ganglion is concerned with", "exp": null, "cop": 1, "opa": "Taste", "opb": "Lacrimation", "opc": "Saliva", "opd": "Sweating", "subject_name": "Anatomy", "topic_name": null, "id": "ccbf9525-5b17-49dd-918c-e663fb827674", "choice_type": "single"} {"question": "Skin immediately around the umbilicus is supplied by", "exp": "The immediately around the umbilicus is supplied by the 10th thoracic spinal nerve. The umbilicus itself lies in the junction of the veebrae L3 and L4. ref - BDC 6e vol2 pg198-200", "cop": 1, "opa": "Anterior cutaneous branches of thoracoabdominal nerve T10", "opb": "Lateral cutaneous branches of thoracoabdominal nerve T10", "opc": "Anterior cutaneous branches of thoracoabdominal nerve T12", "opd": "Lateral cutaneous branches of thoracoabdominal nerve T12", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "acc16a5e-1f16-45f7-9d79-f4347fce460b", "choice_type": "single"} {"question": "Abductor of larynx is", "exp": "movements and muscles Elevation of larynx; thyrohyoid, mylohyoid Depression of larynx; sternothyroid, sternohyoid Opening inlet of larynx; thyroepiglottic Closing inlet of larynx: aryepiglottic Abductor of vocal cords: posterior cricoarytenoid only Adductor of vocal cords: lateral cricoarytenoid transverse and oblique arytenoids Ref BDC volume 3,sixth edition", "cop": 2, "opa": "Cricothyroid", "opb": "Posterior cricoarytenoid", "opc": "Thyro arytenoid", "opd": "Lateral cricoarytenoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "507664b3-a936-43e9-afcf-a904b294c566", "choice_type": "single"} {"question": "Bone tumor arising from epiphyses is", "exp": "Giant cell tumor refer Robbins page no 1233 Pathogenesis. Current evidence suggests that the neoplas- tic cells of giant cell tumor are primitive osteoblast precur- sors but they represent only a minority of the tumor cells. The bulk of the tumor consists of non-neoplastic osteoclasts and their precursors. The neoplastic cells express high levels of RANKL, which promotes the proliferation of osteoclast precursors and their differentiation into mature osteoclasts RANK expressed by these cells. However, the feedback between osteoblasts and osteoclasts that nor- mally regulates this process during bone remodeling is absent. What results is a localized but highly destructive resorption of bone matrix by reactive osteoclasts. Giant cell tumors arise in the epiphysis but may extend into the metaphysis. The majority arise around the knee (distal femur and proximal tibia), but viually any bone can be involved. The typical location of these tumors near joints frequently causes ahritis-like symptoms. Occa- sionally, they present with pathologic fractures. Most are solitary;", "cop": 4, "opa": "Osteogenic sarcoma", "opb": "Ewings sarcoma", "opc": "Giant cell tumor", "opd": "Chondromyxoid fibroma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "bb14ea81-ba6d-4f73-9951-0542c52573e9", "choice_type": "single"} {"question": "Derivative of 3rd pharyngeal arch", "exp": ".", "cop": 3, "opa": "Hyoid aery", "opb": "On left , aoic arch; on right, proximal pa of right subclan aery", "opc": "Common Carotid aery and proximal pa of internal carotid aery", "opd": "Proximal pa of pulmonary aeries and (on the left only) ductus aeriosus", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "628e1460-30f0-484d-bcd4-775b7a645655", "choice_type": "single"} {"question": "Esophagus stas at the level of", "exp": "Esophagus begins in neck at lower border of cricoid cailage. BD CHAURASIA&;S HUMAN ANATOMY.VOLUME 1. 6TH EDITION.PAGE NO 282", "cop": 2, "opa": "Upper border of cricoid cailage", "opb": "Lower border of cricoid cailage", "opc": "Thyroid cailage", "opd": "Hyoid cailage", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "1b4046ef-8a84-47b8-8cdd-5d04f944a403", "choice_type": "single"} {"question": "The structure passing through the central tendon of diaphragm", "exp": "IVC passes through central tendon at T8 Veebra level *Along with this few branches of right phrenic N passes.", "cop": 1, "opa": "IVC", "opb": "Aoa", "opc": "Sympathetic chain", "opd": "Esophagus", "subject_name": "Anatomy", "topic_name": "Umblicial cord and diaphragm", "id": "60f28b1a-95cf-4aa8-9642-9419b6eb9f6e", "choice_type": "single"} {"question": "Coicosteroids are absolutely contraindicated in the following type of Tuberculosis", "exp": "Ref-KDT 6/e p749 Coicosteroids are absolutely contra-indicated in intestinal TB due to risk of perforation", "cop": 3, "opa": "Miliary", "opb": "Meningeal", "opc": "Intestinal", "opd": "Renal", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "aa479e73-4c6f-42d8-b07a-be7ee1885d35", "choice_type": "single"} {"question": "Acute mesenteric lymphadenitis is caused by", "exp": "Acute mesenteric lymphadenitis is the diagnosis usually given when enlarged, slightly reddened lymph nodes are encountered at the root of mesentery along with normal appendix when a pt. suspected of appendicitis is opened. \"Whether this is a single, discrete entity is unclear, since the causative factor is not known. Some of these patients have an infection with Y. pseudo tuberculosis or Y. enterocolitis, in which case the diagnosis can be established by culture of the mesenteric nodes or by serologic titres. Children seem to be affected more frequently than men.", "cop": 4, "opa": "Ecoli", "opb": "Staphylococcus", "opc": "Hemophilus", "opd": "Yersinia", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "65850fc7-67c9-4068-8dfe-350e935c303b", "choice_type": "single"} {"question": "A typical feature of thoracic veebrae", "exp": "Typical Thoracic VeebraA. The body is hea-shaped with roughly the same measurements from side to side and anteroposteriorly. On each side, it bears two costal demifacets.B. The veebral foramen is comparatively small and circular.C. The veebral arch1. The pedicles are directed straight backward. The superior veebral notch is shallow, while the inferior veebral notch is deep and conspicuous.2. The laminae overlap each other from above.3. The superior aicular processes project upwards from the junction of the pedicles and laminae. The aicular facets are flat and are directed backward and a little laterally and upwards. This direction permits rotatory movements of the spine.4. The inferior aicular processes are fused to the laminae. Their aicular facets are directed forwards and slightly downwards and medially.5. The transverse processes are large and are directed laterally and backward from the junction of the pedicles and laminae. The anterior surface of each process bears a facet near its tip, for aiculation with the tubercle of the corresponding rib.In the upper six veebrae, the costal facets on the transverse processes are concave and face forwards and laterally. In lower six, the facets are flat and face upwards, laterally and slightly forwards.6. The spine is long and is directed downwards and backward. The fifth to ninth spines are the longest, more veical and overlap each other. The upper and lower spines are less oblique in direction.Ref: Chaurasia; Volume 1 Chapter 13; Bones and Joints of the Thorax", "cop": 1, "opa": "Body is hea shaped", "opb": "Large body", "opc": "Triangular veebral foramen", "opd": "Spine is sho", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1235e4a9-742a-4115-8d3f-847c4f062e7d", "choice_type": "single"} {"question": "Following inflammatory cells are predominantly seen in tissue with", "exp": ".", "cop": 2, "opa": "Bacterial pneumonia", "opb": "Dirofilaria infestation", "opc": "Infectious mononucleosis", "opd": "Tuberculosis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "99d0ae34-5b05-4813-af1b-a6d7d821c7e8", "choice_type": "single"} {"question": "Upper premolars are supplied by", "exp": null, "cop": 2, "opa": "Anterior superior alveolar", "opb": "Middle superior alveolar", "opc": "Posterior superior alveolar", "opd": "Inferior alveolar", "subject_name": "Anatomy", "topic_name": null, "id": "0fe05059-5c92-4bfe-b406-87aad4994118", "choice_type": "single"} {"question": "Most common site of prostatic carcinoma", "exp": "Most prostate cancers are slow growing; however, some grow relatively quickly. The cancer cells may spread from the prostate to other pas of the body, paicularly the bones and lymph nodes. It may initially cause no symptoms. ref - BDC vol2 6e pg 402", "cop": 3, "opa": "Anterior lobe", "opb": "Median lobe", "opc": "Posterior lobe", "opd": "Central zone", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "04772dbb-a4f0-4004-9dbb-4feff1413d90", "choice_type": "single"} {"question": "In the treatment of hydatid cyst, PAIR is contraindicated in", "exp": "Contraindication to PAIR Inaccessible location Pulmonary hydatid cyst Complicated cyst( communicating with biliary tract)", "cop": 1, "opa": "Lung cyst", "opb": "Size >5 cm", "opc": "Not amenable to treatment with albendazole", "opd": "Multiple", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "4ff86f14-bdbb-4637-84b0-23b0291962b6", "choice_type": "single"} {"question": "Taste sensation to anterior 2/3 of tongue is supplied by", "exp": "D. i.e. Chorda tympani nerve", "cop": 4, "opa": "Glossopharyngeal nerve", "opb": "Jacobson's nerve", "opc": "Trigeminal nerve", "opd": "Chorda tympani nerve", "subject_name": "Anatomy", "topic_name": null, "id": "d8d3164e-d8e9-4323-bc43-b190712f80f0", "choice_type": "single"} {"question": "The connection between External and Internal Jugular vein is", "exp": "In the middle of the neck, the internal jugular vein may communicate with the external jugular vein through the oblique jugular vein which runs across the anterior border of the sternocleidomastoidReference: Chourasia; 6th edition; 86th page", "cop": 2, "opa": "Posterior External Jugular vein", "opb": "Oblique Jugular vein", "opc": "Anterior Jugular vein", "opd": "Transverse cervical vein", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "0d4bc617-f380-4959-83c5-7a4c2dd5f3c0", "choice_type": "single"} {"question": "Nuclei deep within the medial temporal lobes of the brain", "exp": "The amygdala (almond shaped) is pa of the basal ganglia, and is situated in the temporal lobe. It has many connections with other pas of the brain, most paicularly with the limbic system, for which reason it is considered pa of the limbic system (although not pa of the limbic lobe itself). The amygdala is critically involved in computing the emotional significance of events. The raphe nuclei are a moderate-size cluster of nuclei found in the brain stem. Their main function is to release serotonin to the rest of the brain.The Dentate nucleus is located within the deep white matter of each cerebellar hemisphere. It is the largest of the four deep cerebellar nuclei, the others being the fastigial nucleus and the interposed nucleus (globose and emboliform nuclei combined). It is responsible for the planning, initiation and control of volitional movements.The red nucleus is a structure in the rostral midbrain involved in motor coordination.", "cop": 1, "opa": "Amygdala", "opb": "Raphae nucleus", "opc": "Dentate nucleus", "opd": "Red nucleus.", "subject_name": "Anatomy", "topic_name": null, "id": "060e34eb-1080-43a2-ba41-07ef4f698682", "choice_type": "single"} {"question": "Paraxial mesoderm contributes to the development of", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:62At first the cells of the paraxial mesoderm are homogenously arranged. later,the mesoderm gets segmentedThe segments are of two categories, somitomeres, and somitesOccipital somites form muscles of the tongue. somites form the axial skeleton, skeletal muscle, and pa of the skin", "cop": 3, "opa": "Parietal peritoneum", "opb": "Visceral peritoneum", "opc": "Skeletal muscles", "opd": "Peritoneal cavity", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "36f470dc-6b01-40fa-abde-d6f2cc470de4", "choice_type": "single"} {"question": "Vegetations on under surface of cusps are found in", "exp": "Refer robbins 9/e 562 Vegetations of libman sacks endocarditis occur on surface of cusps.both surfaces are involved but most commonly affects under surface", "cop": 2, "opa": "Infective endicarditis", "opb": "Libman sacks endocarditis", "opc": "SABE", "opd": "Rheumatic fever", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "fd01608a-7c19-4cae-a606-a044631f70b3", "choice_type": "single"} {"question": "Most common cerebellar tumor in children", "exp": "Refer Robbins page no 8/e", "cop": 3, "opa": "Medullobalstoma", "opb": "Epdendymoma", "opc": "Astrocytoma", "opd": "PNET", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4097ed6a-e27b-413d-91b9-c3c77a69b939", "choice_type": "single"} {"question": "Paranasal sinuses present at bih", "exp": "The sinuses are rudimentary or even absent at bih.They enlarge rapidly during the age of 6 to 7 years i.e, at thevtime of eruption of permanent teeth and then after pubey.From bih to adult life, the growth of the sinuses is due to the enlargement of the bones; in old age, it is due to resorption of the surrounding cancellous bone. Ethmoid and maxillary sinuses present at bih Ref BDC volume;3.Sixth edition", "cop": 2, "opa": "Frontal and maxillary", "opb": "Ethmoid and maxillary", "opc": "Frontal and ethmoid", "opd": "Sphenoid and ethmoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "aee01cae-e318-41da-80e9-e2e0d0db0ffe", "choice_type": "single"} {"question": "Brunner&;s glands are present in", "exp": "Submucosal glands of duodenum are Brunner's glands, they are mucus, bicarbonate-secreting glands. This helps in protecting duodenal epithelium from acidic secretions of the stomach.", "cop": 3, "opa": "Esophagus", "opb": "Stomach", "opc": "Duodenum", "opd": "Ileum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "34207b56-d689-4f0b-ae14-af41925caaa2", "choice_type": "single"} {"question": "Pancreas is derived from", "exp": "Pancreas is derived from foregut. Liver and pancreas are present at the junction of foregut and midgut. Oesophagus,stomach,liver,pancreas and duodenum are derived from endoderm of foregut.", "cop": 1, "opa": "Foregut", "opb": "Midgut", "opc": "Hindgut", "opd": "Notochord", "subject_name": "Anatomy", "topic_name": "Mesentry, neurovascular bundle", "id": "eed4da6f-60fb-4123-b5a4-404dea2f39ed", "choice_type": "single"} {"question": "Nerve supply to vocal cords is by", "exp": null, "cop": 4, "opa": "Internal laryngeal nerve", "opb": "Recurrent laryngeal nerve", "opc": "Superior laryngeal nerve", "opd": "Internal and recurrent laryngeal nerves", "subject_name": "Anatomy", "topic_name": null, "id": "739e8656-55f2-4ba6-b962-a75d2ccf91c7", "choice_type": "single"} {"question": "Kidney coex contain", "exp": "Malpighian corpuscle contains bowman capsule and glomerulus which is present in renal coex. End of renal pyramids called papilla along with minor calyx is present in Renal medulla which is inner poion of kidney.", "cop": 2, "opa": "Renal pyramids", "opb": "Malpighian corpuscles", "opc": "Renal papilla", "opd": "Minor calyces", "subject_name": "Anatomy", "topic_name": "GIT 1", "id": "0fd23f60-2194-429f-b917-75e17062cd2d", "choice_type": "single"} {"question": "Ureter dervies its blood supply from", "exp": "The aerial supply of the middle ureter is derived from the common iliac and gonadal aeries. Finally, the distal ureter is supplied by branches of the common iliac and internal iliac branches, paicularly uterine and superior vesical aeries.The venous drainage is paired with the aeries. ref - BDC 6e vol2 pg318", "cop": 1, "opa": "Renal aery", "opb": "Gonadal vessel", "opc": "Common iliac aery", "opd": "Inferior vesical aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "33455ad0-9f18-490e-915b-48741ad35b1c", "choice_type": "single"} {"question": "Most common nerve involved in an intracranial aneurysm is", "exp": "D i.e. Occulomotor nerveIntra cranial aneurysm commonly presents with either an occulomotor (IIIrd)or abducent (VIth) nerve palsy", "cop": 4, "opa": "Trochlear", "opb": "VII", "opc": "VIII", "opd": "Oculomotor", "subject_name": "Anatomy", "topic_name": null, "id": "5ce65e9b-33a8-49d3-9bca-44ca34c9159e", "choice_type": "single"} {"question": "Lower leg perforators are named after", "exp": ".", "cop": 1, "opa": "Cockett", "opb": "Boyd", "opc": "Dodd", "opd": "May or kuster", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "41b278cb-be90-4a29-aae4-835ad684cf90", "choice_type": "single"} {"question": "CRAFFT Questionnaire is used for", "exp": ".", "cop": 3, "opa": "Screening for physical dexterity", "opb": "Screening for thyroid disorders", "opc": "Screening Adolescents for drug abuse", "opd": "Screening parents for abusive tendencies", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0de0f027-d483-419d-af5d-38f292aecc17", "choice_type": "single"} {"question": "Neurogenic shock is characterized by", "exp": "High spinal cord injury there is failure of sympathetic outflow and adequate vascular tone (neurogenic shock). The cause in sepsis is less clear but is related to the release of bacterial products (endotoxin) and the activation of cellular and humoral components of the immune system. There is maldistribution of blood flow at a microvascular level with aeriovenous shunting and dysfunction of cellular utilization of oxygen.", "cop": 4, "opa": "Hypeension and tachycardia", "opb": "Hypeension and bradycardia", "opc": "Hypotension and tachycardia", "opd": "Hypotension and bradycardia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "276efef0-0d32-42e8-a854-fe603d2f8906", "choice_type": "single"} {"question": "Best graft for infra inguinal approach bypass", "exp": "The great saphenous veins should be used preferentially in all bypasses, especially in those reconstructions using below-knee popliteal and small tibial aeries as the distal target vessels. PTFE grafts can be used for bypasses to above-knee popliteal aerial segments with satisfactory patency rates. Ref: Sabiston 20th edition Pgno: 1774", "cop": 4, "opa": "Dacron", "opb": "PTFE", "opc": "Polyester", "opd": "Autologous vein", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "a1ea9de3-ff5b-4458-b9da-1cff87d31767", "choice_type": "single"} {"question": "Lithogenic bile has the following propeies", "exp": "An excess of cholesterol relative to bile acids and phospholipids allows cholesterol to form crystals and such bile is called lithogenic or supersaturated bile Lithogenic bile Increased Biliary cholesterol Obesity Cholesterol rich diet Cholesterol therapy Decreased Bile Acids Primary biliary cirrhosis OCP's Mutation of CYP7A1 gene Impaired enterohepatic circulation of bile acids : Ileal disease or resection, cholestyramine or colestipol(bile acid sequestrants) Decreased biliary Lecithin MDR-3 gene mutation leads to defective Lecithin secretion inBile Ref : Sabiston 20th edition Pgno :1492", "cop": 2, "opa": "Increased Bile and cholesterol ratio", "opb": "Decreased Bile and cholesterol ratio", "opc": "Equal bile and cholesterol ratio", "opd": "Decreased cholesterol only", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "929c5117-cedb-47b9-8130-3fad0933a8a8", "choice_type": "single"} {"question": "Muscle not supplied solely by Median nerve", "exp": "Flexor pollicis brevis is primarily supplied by median nerve. But it's deep head gets supply from Ulnar nerve.", "cop": 3, "opa": "Abductor pollicis brevis", "opb": "Opponens pollicis", "opc": "Flexor pollicis brevis", "opd": "Pronator quadratus", "subject_name": "Anatomy", "topic_name": null, "id": "71c4c578-d0af-47e1-acf6-68ddd5d50d45", "choice_type": "single"} {"question": "The tip of the T3 spinous proces corresponds to", "exp": "The tip of the T3 spinous process corresponds to the root of the spine of the scapula. Other impoant surface markings of scapula: Superior angle of scapula : at the level of 2nd rib and veebrae T2. Inferior angle of scapula: opposite the T7 veebral spinous process. Spinous process and their significance Spinous process Significance C2 spinous process Most superior bony protuberance in the midline inferior to the skull C7 spinous process Lower extent of ligamentum nuchae T3 spinous process Level of the root of the spine of the scapula T7 spinous process Level of the inferior angle of the scapula T12 spinous process Midpoint of a veical line between the inferior angle of the scapula and the iliac crest L4 spinous process Level marks the highest point of the iliac crest S2 spinous process Sacral dimples that mark the position of the posterior superior iliac spine are level Ref: Gray's Anatomy 41st edition Pgno: 748", "cop": 3, "opa": "Lower extent of ligamentum nuchae", "opb": "Superior angle of scapula", "opc": "Root of the spine of scapula", "opd": "Inferior angle of scapula", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "752eed58-deae-4e0b-89c2-36c83e1894e6", "choice_type": "single"} {"question": "Dissoscited sensory loss is seen in", "exp": "Refer Robbins page no 1258 Syringomyelia is a generic term referring to a disorder in which a cyst or cavity forms within the spinal cord. This cyst, called a syrinx, can expand and elongate over time, destroying the spinal cord. The damage may result in loss of feeling, paralysis, weakness, and stiffness in the back, shoulders, and extremities.", "cop": 1, "opa": "Synringomyelia", "opb": "Viatmain B12 deficiency", "opc": "Transverse myelitis", "opd": "Pellagra", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "3e3e65ae-7fe5-40da-a499-17e7416f0d20", "choice_type": "single"} {"question": "A patient needs antibiotic treatment for Aificial valve, culture positive infective entercoccal endocarditis. His medical history include several anaphylactic reaction to penicillin G during the past year. The best approach would be treatment with", "exp": "Ref-KDT 6/e 732 * Severe allergy to penicillins rule out the use of amoxicillin and cefazolin. * Vancomycin is highly effective against MRSA and enterococcal intections. * Drugs for VRSA and VRE (Vancomvcin Resistant enterococcus faecalis) include linezolid and daptomycin.", "cop": 4, "opa": "Amoxicillin clavulanic acid", "opb": "Aztreonam", "opc": "Cefazolin plus gentamicin", "opd": "Vancomycin", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "e1891651-bf7a-4679-bc07-d661283e32e7", "choice_type": "single"} {"question": "Structure passing through anterior part of jugular foramen", "exp": null, "cop": 1, "opa": "Inferior petrosal sinus", "opb": "Internal jugular vein", "opc": "Accessory meningeal artery", "opd": "X, XI nerve", "subject_name": "Anatomy", "topic_name": null, "id": "9795f8c8-6b2d-434c-b883-e1bd72c2f02e", "choice_type": "single"} {"question": "Somites develop from", "exp": "Ans. a (Paraxial mesoderm) (Ref. Human Embryology by IB Singh; 6th/ pg. 46)# Splanchnopleuric mesoderm (from lateral plate mesoderm) forms mesothelial covering of visceral organs;# Intermediate plate mesoderm forms urinary and genital systems, adrenal cortex;# Somites that are derived from paraxial mesoderm form the axial skeleton, voluntary musculature, etc.DERIVATIVES OF THE MESODERMAL GERM LAYERRegions of the epiblast that migrate and ingress through the primitive streak have been mapped and their ultimate fates determined, as appended below:# Cells that ingress through the cranial region of the node become notochord;# Those migrating at lateral edges of node and from cranial end of the streak become paraxial mesoderm:# Cells migrating through the midstreak region become intermediate mesoderm:# Those migrating through the more caudal part of the streak form lateral plate mesoderm: and# Cells migrating through the caudal-most part of the streak contribute to extraembrvonic mesoderm.# Intermediate mesoderm connects paraxial and lateral plate mesoderm.Additional educational point:# Sclerotomes give rise to vertebral arches (dorsal sclerotome), vertebral bodies (ventral sclerotome), base of the skull, costal processes and ultimately ribs (in thoracic region).", "cop": 1, "opa": "Paraxial mesoderm", "opb": "Lateral plate mesoderm", "opc": "Intermediate mesoderm", "opd": "Extra-embryonic coelom", "subject_name": "Anatomy", "topic_name": "Fertilization and Development of Embryo", "id": "42ce71f0-6b89-4dda-9f37-059ef3c8098f", "choice_type": "single"} {"question": "Operculated sulcus is another name of", "exp": null, "cop": 2, "opa": "Central Sulcus", "opb": "Lunate Sulcus", "opc": "Collateral Sulcus", "opd": "Calcarine Sulcus", "subject_name": "Anatomy", "topic_name": null, "id": "38603189-a522-4b9c-9e06-2e5ee16b9f4b", "choice_type": "single"} {"question": "The length of oesophagus in adult is", "exp": "(25 cm) (267-IBS4th) (134-35-Snell 7th)OESOPHAGUS* It extends from the lower part of the neck to the upper part of the abdomen.* The oesophagus is about 25 cm long (10 inch)* The pharyngo-oesophageal junction is the narrowed part of the alimentary canal except for the vermiform appendix.* The oesophagus begins in the neck at the lower border of the cricoid cartilage. It ends by the opening into the stomach at its cardiac end at the level of 11th thoracic vertebra.Constriction-4DistanceCervicalBronchoaorticDiaphragmaticDuodenumDistance from incisor teeth6 in (15 cm)10 in (25 cm)16 in (41 cm)22-26 in (56-66 cm)Distance from nostrils7.2 in (18 cm)11.2 in (28 cm)17.2 in (44 cm)23.2-27.2 in (59-69 cm)Arterial supply* Upper third = Inferior thyroid artery** Middle third = Oesophageal branches of the descending thoracic aorta** Lower third = Left gastric artery*", "cop": 4, "opa": "10 cm", "opb": "15 cm", "opc": "20 cm", "opd": "25 cm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "51c4c296-d89a-4717-abee-e36a14347408", "choice_type": "single"} {"question": "Antineutrophil cytoplasmic antibodies(ANCA) are seen in", "exp": "Refer robbins 9/e p511 Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small- and medium-sized blood vessels. Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis (WG), is a long-term systemic disorder that involves both granulomatosis and polyangiitis. It is a form of vasculitis (inflammation of blood vessels) that affects small- and medium-size vessels in many organs but most commonly affects the upper respiratory tract and the kidneys. Therefore, the signs and symptoms of GPA are highly varied and reflect which organs are supplied by the affected blood vessels. Typical signs and symptoms include nosebleeds, stuffy nose and crustiness of nasal secretions, and inflammation of the uveal layer of the eye. Damage to the hea, lungs and kidneys can be fatal.", "cop": 1, "opa": "Wagner's granulomatosis", "opb": "Diabetes mellitus", "opc": "Rheumatoid ahritis", "opd": "Charg straus syndrome", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "02551af2-43af-448b-8531-9ebe109f19de", "choice_type": "single"} {"question": "Commonly affected nerve in anterior shoulder dislocation is", "exp": "-dislocation of shoulder joint mostly occurs inferiorly because the joint is least suppoed on this aspect.It often injures the axillary nerve because of its close relation to the inferior pa of the joint capsule. -However clinically it is described as anterior or posteriordislocation indicating whether the humeral head has descended anterior or posterior to the infraglenoid tubercle of the scapula and long head of triceps. -Reference: Textbook of anatomy,Upper llimb and thorax, Vishram Singh, 2nd editon, page no.78", "cop": 3, "opa": "Musculocutaneous nerve", "opb": "Radial nerve", "opc": "Axillary nerve", "opd": "Median nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "40462349-fcb4-45f7-b5b5-bb9610594ec5", "choice_type": "single"} {"question": "Pouch of Douglas is situated between", "exp": "The recto-uterine pouch or pouch of douglas is the extension of the peritoneal cavity between the rectum and the posterior wall of the uterus in the female human body. imageref - semantischolar.org", "cop": 4, "opa": "Bladder and the uterus", "opb": "Bladder and public symphysis", "opc": "Bladder and the rectum", "opd": "Uterus and rectum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "41e7c75e-f03b-4a79-9ccf-6530e4bdf00d", "choice_type": "single"} {"question": "Angle of jaw (or) skin over angle of mandible is supplied by", "exp": null, "cop": 1, "opa": "Great auricular nerve", "opb": "Lesser occipital nerve", "opc": "Greater occipital nerve", "opd": "Posterior auricular nerve", "subject_name": "Anatomy", "topic_name": null, "id": "778a7522-0afd-454b-8f14-8e09a60ced57", "choice_type": "single"} {"question": "Internal arcuate fibres of medulla comes from", "exp": ".", "cop": 4, "opa": "Hypoglossal nucleus", "opb": "Dorsal nucleus of vagus", "opc": "Nucleus tractus solitarius", "opd": "Nucleus gracilis and cuneatus", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "adc94a4c-1eaa-4181-8318-ca3e93379953", "choice_type": "single"} {"question": "Main suppo of uterus is provided by following structure", "exp": "The cervix protrudes into the vagina. The uterus is held in position within the pelvis by condensations of endopelvic fascia, which are called ligaments. These ligaments include the pubocervical, transverse cervical ligaments or Mackenrodt's ligaments or cardinal ligaments, and the uterosacral ligaments. Ref - BDC 6e vol2 pg 391", "cop": 2, "opa": "Round ligament", "opb": "Cardinal ligament", "opc": "Vesico-uterine fold", "opd": "Broad ligament", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "365a4278-9a70-433c-a2b1-0ce2883e6547", "choice_type": "single"} {"question": "Valve of heister is seen in", "exp": "Ans. is 'a' i.e., Cystic ductThe mucous membrane of the cystic duct forms a series of 5-12 crescentic folds, arranged spirally to form the so called spiral valve of Heister. This is not a true valve.Also knowHamanns pouch - dilated posteromedial wall of neck of gall bladder.Sphincter choledochus - always present - terminal pa of bile ductSphincter pancreaticus - usually present - terminal pa of pancreatic ductSphincter ampullae (of Oddi) - surrounds the hepatopancreatic ampulla", "cop": 1, "opa": "Cystic duct", "opb": "Common bile duct", "opc": "Common hepatic duct", "opd": "Pancreatic duct", "subject_name": "Anatomy", "topic_name": null, "id": "77d64684-48fd-4a39-beba-6523a64a49c6", "choice_type": "single"} {"question": "Primary curvatures of veebral column are", "exp": ".", "cop": 2, "opa": "Cervical & lumbar", "opb": "Thoracic & sacral", "opc": "Cervical & thoracic", "opd": "Thoracic & Lumbar", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "adc90818-5743-433e-abda-d9c21b792315", "choice_type": "single"} {"question": "Sensory innervation of cornea is by nerve", "exp": "The trigeminal nerve (V) - Three Divisions V1: Ophthalmic nerve V2: Maxillary nerve V3: Mandibular nerve Ophthalmic nerve division Ophthalmic nerve is sensory. Its branches are: Frontal nerve 1. Supratrochlear: upper eyelid, conjunctiva, lower pa of forehead. 2. Supraorbital: frontal air sinus, upper eyelid, forehead, scalp till veex. Nasociliary nerve 1. Posterior ethmoidal: sphenoidal air sinus, posterior ethmoidal air sinuses. 2. Long ciliary: sensory to eyeball. 3. Branch to ciliary ganglion 4. Infratrochlear: both eyelid, side of nose, lacrimal sac. 5. Anterior Ethmoidal: a). Middle and anterior ethmoidal sinuses. b). Medial internal nasal c). Lateral internal nasal d). external nasal: skin of ala of vestibule and tip of nose, Lacrimal nerve Lateral pa of upper eyelid: conveys secretomotor fibers from zygomatic nerve to lacrimal gland.", "cop": 3, "opa": "3rd", "opb": "4th", "opc": "5th", "opd": "6th", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "aa1f29ea-fe56-4ae4-988a-8af122963d19", "choice_type": "single"} {"question": "Muscles spared during injury to cranial root of accessory nerve", "exp": "All muscles of the pharynx, except stylopharyngeus, are supplied by the pharyngeal plexus", "cop": 1, "opa": "Stylopharyngeus", "opb": "Palatopharyngeus", "opc": "Salpingopharyngeus", "opd": "Cricopharyngeus", "subject_name": "Anatomy", "topic_name": null, "id": "6bfbb608-ec8c-40d0-a226-8d8461300c9a", "choice_type": "single"} {"question": "The major venous return of the hea, the coronary sinus, empties into", "exp": "The coronary sinus empties directly into the right atrium (like IVC, SVC) near the conjunction of the posterior interventricular sulcus and the coronary sulcus.Reference: Chaurasia; 6th edition", "cop": 3, "opa": "IVC", "opb": "Left atrium", "opc": "Right atrium", "opd": "Right ventricle", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ed195213-cbdc-44e6-9719-974e3c927452", "choice_type": "single"} {"question": "Mosaic pattern of lamellar bone histology is found in", "exp": "Refer Robbins page no 1285 Paget Disease (Osteitis Deformans) Paget disease is a disorder of increased, but disordered and structurally unsound, bone mass. This unique skeletal disease can be divided into three sequential phases: (1) an initial osteolytic stage, (2) a mixed osteoclastic-osteoblastic stage, which ends with a predominance of osteoblastic activity and evolves ultimately into (3) a final burned-out quiescent osteosclerotic stage", "cop": 3, "opa": "Osteopetrosis", "opb": "Osteoid Osteoid", "opc": "Osteitis deformans", "opd": "Osteomalacia", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "ae65971e-ed01-4a46-af8e-2427c3fe2dad", "choice_type": "single"} {"question": "A drug X is secreted through renal tubles,tubular secretion of this drug can be confirmed if renal cleraclea of drug X is", "exp": "Ref-KDT 6/e p30 Atter filtration from glomerulus, a drug may undergo two processes (tubular reabsorption and tubular secretion) before going out from the body i.e renal clearance. Suppose 100 mg of a drug is filtered by glomerulus and the ren clearance is 150mg,it mean 50mg is coming from somewhere else, i.e. tubular secretion must be present. However,we cannot say that reabsorption is not occuring because if 20 mg is reabsorbed and 70 mg is secreted, same thing can Suppose, 100 mg of a drug is filtered but renal clearance is 50 mg. Therefore, 50 mg must have gone somewhere i.e. tubular reabsorption must be occuring, Again, we cannot say that tubular secretion is not present", "cop": 1, "opa": "More than the GFR", "opb": "Equals to the GFR", "opc": "Less than the GFR", "opd": "More than volume of distrubtion", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "611bd245-e86d-4a2c-b23b-bdfda797043d", "choice_type": "single"} {"question": "Secondary spermatocyte is", "exp": "Secondary spermatocyte is haploid formed by meiotic division Description Human embryology Tenth edition", "cop": 1, "opa": "Haploid (n) and 2N", "opb": "Haploid (2n) and 2N", "opc": "Diploid (2n) and N", "opd": "Diploid (n) and 2N", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94b1ce46-a0fc-45de-b2ef-4146fc3f6952", "choice_type": "single"} {"question": "Length of inguinal canal", "exp": "INGUINAL CANAL:- Oblique intermuscular passage in the lower pa of the anterior abdominal wall.Extends from deep inguinal ring to superficial.Deep ring- oval opening in fascia transversalis.1.25 cm above mid-inguinal point.Superficial ring: triangular gap in external oblique aponeurosis. Length: 4cm Directed downwards forwards and medially. BOUNDARIES:-1. Anterior wall A. To the whole extend: skinsuperficial fascia and external oblique aponeurosis.B. Lateral one third: internal oblique muscle 2. Posterior wall A. Whole extend fascia transversalis, extraperitoneal tissue, the parietal peritoneum.B. Medial two third: conjoint tendon, reflected pa of inguinal ligament. 3. Roof:arched fibres of internal oblique and transversus abdominis.4. Floor: grooved upper surface of inguinal ligament. Structures passing through:-1. Spermatic cord(males) Round ligament of uterus (f)2. Ilioinguinal nerve. {Reference: BDC 6E pg213}", "cop": 2, "opa": "2.5 cm", "opb": "4 cm", "opc": "10 cm", "opd": "15 cm", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7f4820bd-b3bb-4e12-9ca0-aaa566c38cfd", "choice_type": "single"} {"question": "Type of joint at site marked by the arrow", "exp": "Image shows costotransverse joint. Costotransverse joint is the joint formed between the facet of the tubercle of the rib and the adjacent transverse process of a thoracic veebra. It is a type of synol joint.", "cop": 4, "opa": "Syndesmosis", "opb": "Synahrosis", "opc": "Symphysis", "opd": "Synol Joint", "subject_name": "Anatomy", "topic_name": "NEET Jan 2020", "id": "eee40b3f-5d15-4f0b-808b-cfc3455c0a80", "choice_type": "single"} {"question": "A patient inventing new words, is a feature of", "exp": "patient inventing new words which is not present in one's dictionary is called neologism neurosis is called for the group of disorders where there is a distress towards the symptoms and patient has insight towards one's own illnes. some of the neurosis disorders are anxiety disorder, phobia, adjustment disorders and others OCD is Obsessive compulsive disorder, it is assosiated with obsessions and compulsions obsessions are recurrent intrusive irrelevant distressing irresistable ego dystonic thoughts van gogh syndrome is self mutilation syndrome inpsychosis Ref.Kaplon and sadock, synopsis o psychiatry, 11 th edition, pg no.192", "cop": 2, "opa": "Neurosis", "opb": "Schizophrenia", "opc": "OCD", "opd": "Von-Gogh syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "09869bd7-dd66-4d81-b71e-d0917c96573d", "choice_type": "single"} {"question": "Most pathognomonic sign of irreversible cell injury", "exp": "Ref, Robbins 7/ep12,9/ep50", "cop": 1, "opa": "Amorphous densities in mitochondria", "opb": "Swelling of the cell membrane", "opc": "Ribosomes detached from endoplasmic reticulum", "opd": "Clumping of the nucleus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cda2f7c4-1ebc-484a-821c-609a1d82e4dc", "choice_type": "single"} {"question": "Lardaceous spleen is due to deposition of amyloid in", "exp": "Ref Robbins 9/e p261 Spleen. Amyloidosis of the spleen often causes moderate or even marked enlargement (200 to 800 gm). For obscure reasons, either of two patterns may develop. The deposits may be viually limited to the splenic follicles, producing tapioca-like granules on gross examination (\"sago spleen\"), or the amyloidosis may principally involve the splenic sinuses, eventually extending to the splenic pulp, with formation of large, sheetlike deposits (\"lardaceous spleen\"). In both pat- terns, the spleen is firm in consistency. The presence of blood in splenic sinuses usually impas a reddish color to the waxy, friable deposits.", "cop": 1, "opa": "Sinusoids of red pulp", "opb": "White pulp", "opc": "Pencillary aery", "opd": "Splenic trabeculae", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a3855aef-cd57-42d4-9412-d14fa3189496", "choice_type": "single"} {"question": "applied tension is used for", "exp": "Applied tension is used for blood injection phobia where there is hypotension and falls, in these patients falls is because of vasodilatations when we use applied tension there may be constriction of hand and leg muscles which prevents vasodilation and prevents falls. Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 2, "opa": "agarophobia", "opb": "blood injection phobia", "opc": "movement disorders", "opd": "thanatophobia", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "f6d4556b-3e96-4cb4-aea0-f691c0c589ba", "choice_type": "single"} {"question": "Russell bodies are accumulations of", "exp": "Ref Robbins 9/e p63 Russell bodies are eosinophilic, large, homogeneous immunoglobulin-containing inclusions usually found in a plasma cell undergoing excessive synthesis of immunoglobulin; the Russell body is characteristic of the distended endoplasmic reticulum. They are found in the peripheral areas of tumors. Russell bodies are thought to have originated as an SOS compament, where abnormal proteins that are not secreted, but have fled intracellular degradation, can gather without blocking normal secretory pathways. The excess immunoglobulin builds up and forms intracytoplasmic globules, which is thought to be a result of insufficient protein transpo within the cell. This causes the proteins to neither be degraded or secreted and stay stored in dilated cisternae. In 1949, Pearse discovered that Russell bodies also contain mucoproteins that are secreted by plasma cells. Russell bodies are not tissue specific; during research they were induced in rat glioma cells.Russell bodies were found to have positive reactions to PAS stain, CD 38 and CD 138 stains. Plasma cellsthat contain Russell bodies and are stained with H&E stain are found to be autofluorescent, while those without Russell bodies are not autofluorescent. Russell bodies tend to be found in places with chronic inflammation. Multiple aggregates of Russell bodies create what are known as Mott cells", "cop": 2, "opa": "Cholesterol", "opb": "Lipoprotein", "opc": "Immunoglobulin", "opd": "Phospholipid", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "eab3bcb3-a241-48a1-b178-2a90dfcbc159", "choice_type": "single"} {"question": "Commonest type of intracranial tumor is", "exp": "Reference 1315", "cop": 4, "opa": "Astrocytoma", "opb": "Medulloblastoma", "opc": "Meningioma", "opd": "Secondaries", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7bfebe56-e9ef-4234-8e6c-427ab774017c", "choice_type": "single"} {"question": "The chief source of blood supply to head and neck of femur is derived from", "exp": "The head of the femur is paly supplied by a branch of obturator aery along the ligamentum teres.Main aerial supply is from retinacular aeries, branches of the medial femoral circumflex aery.These aeries get injured in intracapsular fracture of neck of femur, leading to avascular necrosis of the head.BDC 6th edition (Abdomen & lower limb) pg: 32", "cop": 3, "opa": "Acetabular branches of obturator aery", "opb": "Acetabular branches of medial circumflex femoral aery", "opc": "Retinacular branches of medial circumflex femoral aery", "opd": "Nutrient aery of femur", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e8766ea5-ee4c-4c1f-8b26-28411d9eb1b3", "choice_type": "single"} {"question": "Summit of medial longitudinal arch", "exp": "Summit of medial longitudinal arch is Talus.\nSummit of lateral longitudinal arch is Calcaneum.", "cop": 2, "opa": "Calcaneum", "opb": "Talus", "opc": "Navicular", "opd": "Medial Cuneiform", "subject_name": "Anatomy", "topic_name": null, "id": "cadbf490-a9d2-4bae-9aa1-efe6e65f9aa2", "choice_type": "single"} {"question": "Tolllike receptor, recognise bacterial products and stimulate immune response by", "exp": "Ref Robbins 9/e p187 The ability of immune system to recognize moleculesthat are broadly shared by pathogens is, in pa, due to the presence of Immune receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells, cells of the adaptive immunity (T and B lymphocytes) and non immune cells (epithelial and endothelial cells, and fibroblasts). The binding of ligands - either in the form of adjuvant used in vaccinations or in the form of invasive moieties during times of natural infection - to the TLR marks the key molecular events that ultimately lead to innate immune responses and the development of antigen-specific acquired immunity. Upon activation, TLRs recruit adapter proteins(proteins that mediate other protein-protein interactions) within the cytosol of the immune cell in order to propagate the antigen-induced signal transduction pathway. These recruited proteins are then responsible for the subsequent activation of other downstream proteins, including protein kinases(IKKi, IRAK1, IRAK4, and TBK1) that fuher amplify the signal and ultimately lead to the upregulation or suppression of genes that orchestrate inflammatoryresponses and other transcriptional events. Some of these events lead to cytokine production, proliferation, and survival, while others lead to greater adaptive immunity. If the ligand is a bacterial factor, the pathogen might be phagocytosed and digested, and its antigens presented to CD4+ T cells. In the case of a viral factor, the infected cell may shut off its protein synthesis and may undergo programmed cell death (apoptosis). Immune cells that have detected a virus may also release anti-viral factors such as interferons.", "cop": 3, "opa": "Perforin and granzyme mediated apoptosis", "opb": "FADD ligand apoptosis", "opc": "Transcription of nuclear factor mediated by N-FkBwhich recruits cytokine", "opd": "Cyclin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a3840650-8e6b-4eeb-9860-41deb16a312e", "choice_type": "single"} {"question": "Poal vein is formed", "exp": "Poal vein is formed behind the neck of pancreas where the splenic vein and superior mesentric vein terminates and continue as poal vein. Ref: Human anatomy, 7th edition, BD Chaurasia, pg:328", "cop": 3, "opa": "Behind the spleen", "opb": "Behind the tail of pancreas", "opc": "Behind the neck of pancreas", "opd": "Behind the second pa of duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "4d4a0b43-56dc-40c3-82c4-8c5290ec147c", "choice_type": "single"} {"question": "Adson's test is positive in", "exp": "Adson's sign is the loss of the radial pulse in the arm by rotating head to the ipsilateral side with extended neck following deep inspiration . Ref : S. Das surgery 3/e p641", "cop": 1, "opa": "Cervical rib", "opb": "Cervical fracture", "opc": "Cervical spondylosis", "opd": "Cervical dislocation", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "73caa23d-26ad-4678-9fd6-5d2959ebdbe7", "choice_type": "single"} {"question": "Hodgkin's lymphoma caused for by", "exp": "Ref Robbins 9/e p607 One clue stems from the involvement of EBV. EBV is present in the RS cells in as many as 70% of cases of the mixed-cellularity subtype and a smaller fraction of other \"classical\" forms of Hodgkin lymphoma. More impoant, the integration of the EBV genome is identi- cal in all RS cells in a given case, indicating that infection precedes (and therefore may be related to) transformation and clonal expansion. Thus, as in Burkitt lymphoma and B cell lymphomas in immunodeficient patients, EBV infection prob- ably is one of several steps contributing to tumor develop- ment, paicularly of the mixed-cellularity subtype. The characteristic non-neoplastic, inflammatory cell infil- trate is generated by a number of cytokines, some secreted by RS cells, including IL-5 (which attracts and activates eosin- ophils), transforming growth factor-b (a fibrogenic factor), and IL-13 (which may stimulate RS cells through an autocrine mechanism). Conversely, the responding inflammatory cells, rather than being innocent bystanders, produce additional factors such as CD30 ligand that aid the growth and survival of RS cells and contribute fuher to the tissue reaction.", "cop": 1, "opa": "EBV", "opb": "CMV", "opc": "HHV6", "opd": "HHV8", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "71c165d5-905e-4cc7-9792-201ac23b98ef", "choice_type": "single"} {"question": "Type of Sacroiliac joints in pelvis are", "exp": "The pelvic bones are joined by four aiculations (two pairs): Two cailaginous symphyseal joints: the sacrococcygeal joint and the symphysis pubis. These joints are surrounded by strong ligaments anteriorly and posteriorly, which are responsive to the effect of relaxin and facilitate paurition. Two synol joints: the sacroiliac joints. These joints are stabilized by the sacroiliac ligaments, the iliolumbar ligament, the lateral lumbosacral ligament, the sacrotuberous ligament, and the sacrospinous ligament.Reference: Berek and Novak's Gynecology; 14th edition; Chapter 5; Anatomy and Embryology", "cop": 1, "opa": "Synol", "opb": "Primary Cailagenous", "opc": "Secondary Cailagenous", "opd": "Fibrous", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "b75ce1f2-7cf0-45c8-beaa-b03bd702ed61", "choice_type": "single"} {"question": "Basic pathology in cystic fibrosis is", "exp": "Ref Robbins 9/e p222 Cystic fibrosis is an autosomal recessive disorder affecting the lungs, pancreas, intestines, sweat ducts and liver, due to an abnormal salt transpo across the apical border of epithelial cells. Mutations in the CF underlying gene, the cystic fibrosis transmembrane conductance regulator (CFTR) gene, result in most cell types in an misprocessing so that little of the protein reaches the membranes. In case of clinical suspicion and/or doubtful sweat test results, mutation analysis can suppo the diagnosis of CF. Also carrier detection is offered. PATHOPHYSIOLOGY CF is caused by a mutation in the CF transmembrane conductance regulator (CFTR) gene. The CFTR protein produced by this gene regulates the movement of chloride and sodium ions across epithelial cell membranes.Figure 1).Pseudomonas, Haemophilus influenza, and Staphylococcus aureus. These pathogens cause an overwhelming inflammatory response. Ultimately, chronic infection and this repetitive inflammatory response can lead to airway destruction.CF is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly normal. CFTR is involved in production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bih takes place in some areas of the world.", "cop": 1, "opa": "Defect in the transpoation of chloride across epithelia", "opb": "Defect in transpo of sodium across epithelia", "opc": "Defect in transpo of potassium across epithelia", "opd": "Defect in transpo of bicarbonate across epithelia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ebf9177-f6ae-4b41-9b2e-6500fcea9f2a", "choice_type": "single"} {"question": "Grade I lymphedema means", "exp": ".", "cop": 4, "opa": "Pitting edema upto the ankle", "opb": "Pitting edema upto the knee", "opc": "Non pitting edema", "opd": "Edema disappearing after overnight rest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "17cdc1cc-f57a-403a-9109-b38a8a92dbf2", "choice_type": "single"} {"question": "Merkels cells of Epidermis are derived from", "exp": "(C) Neural crest # MERKEL CELLS, which are believed to be derived from the neural crest, contain many large (50-100 nm) dense-cored vesicles, presumably containing transmitters, which are concentrated near the junction with the axon. F.S. Merkel referred to these cells as Tastzellen or \"touch cells\" Merkel cells are found in the skin and some parts of the mucosa (stratum germinativum) of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale (at the bottom of sweat duct ridges) of the epidermis approximately 10 pm in diameter. They also occur in epidermal invaginations of the plantar foot surface called rete ridges. Most often, they are associated with sensory nerve endings, when they are known as Merkel nerve endings (Merkel cell-neurite complex). They are associated with slowly adapting (SA1) somatosensory nerve fibers. They are associated with the sense of light touch discrimination of shapes and textures. They can turn malignant and form the skin tumor known as Merkel cell carcinoma.DERIVATIVES OF NEURAL CRESTDerivative of neural crestDeveloping partsNeurons1. Spinal posterior nerve root ganglion (dorsal root ganglia) 2. Sensory ganglia of V, VII, VIII, IX & X cranial nerves 3. Sympathetic gangliaPiamater & Arachnoid mater (Not duramater)--Schwann cellsNeurolemmal sheaths of all peripheral nervesAdrenal medullaChromaffin tissuePigment cells of skinMelanoblasts; Merkel's cells of epidermisMesenchyme of dental papilla & Odontoblasts--Cells from cranial part of neural crest (Somatomeres)Development of musculature of head & in formation of face", "cop": 3, "opa": "Neural tube", "opb": "Notochord", "opc": "Neural crest", "opd": "Neural pore", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "fdea496c-fd2a-415a-b788-196680960cf7", "choice_type": "single"} {"question": "Phossy jaw is seen in chronic", "exp": "Phossy jaw It is a type of osteomylitis of the jaws observed in chronic phosphorus poisoning. Frequent inhalation of fumes for many years may cause necrosis of the lower jaw in the region of a decayed tooth. It is common among workers, in phosphorus industries, who are exposed to phosphorus fumes Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 432", "cop": 4, "opa": "Sulphur poisoning", "opb": "Chlorine poisoning", "opc": "Fluirine poisoning", "opd": "Phosphorus poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "7a6bb586-4775-4196-aef1-f0cc77bbe51f", "choice_type": "single"} {"question": "Weight of liver", "exp": "A human liver normally weighs 1.44-1.66 kg or1400 - 1600gm. It is both the heaviest internal organ and the largest gland in the human body. ref - BDC 6e Vol2 pg304", "cop": 3, "opa": "600-800 gm", "opb": "1000-1200gm", "opc": "1400-1600gm", "opd": "1800-2000gm", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e6bd9414-69fd-45ad-b3eb-bcff026c54b6", "choice_type": "single"} {"question": "Primitive streak is initiated and maintained by", "exp": "Ans. is 'a' i.e. Nodal gene \"The primitive streak in itself is initiated and maintained by expression of Nodal, a member of the transforming growth factor b (TGFb) family.\" - Longman's Medical embryology 10/e, p 57", "cop": 1, "opa": "Nodal gene", "opb": "BMP4", "opc": "FGF", "opd": "Brachyury gene", "subject_name": "Anatomy", "topic_name": "Fertilization and Development of Embryo", "id": "7e7d4ab7-f198-40df-ae5b-82be55767898", "choice_type": "single"} {"question": "Most common valvular lesion in carcinoid syndrome of the hea is", "exp": ".", "cop": 3, "opa": "AR", "opb": "AS", "opc": "TR", "opd": "MS", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "692d5ffb-fac8-4d8c-8585-8fbfbd755eea", "choice_type": "single"} {"question": "Skin over femoral triangle supplied by", "exp": "GENITOFEMORAL NERVE:- L1 L2Pierces the femoral sheath and overlying deep fascia 2 cm below the midinguinal point.Supplies most of the skin over femoral triangle. ILIOHYPOGASTRIC NERVE:-Branch of lumbar plexus.L1Anterior division. ILIOINGUINAL NERVE:-L1Emerges at the superficial inguinal ring Supplies skin at the root of penis or over the mons pubis in females, the anterior 1/3 rd of scrotum or labia majus, and superomedial aspect of thigh. LATERAL CUTANEOUS NERVE OF THIGH:-L2L3Branch of lumbar plexus Supplies skin over Anterolateral side of thigh and on the anterior pa of gluteal region. {Reference: BDC 6E pg no.42}", "cop": 3, "opa": "Iliohypogastric nerve", "opb": "Ilioinguinal nerve", "opc": "Genitofemoral nerve", "opd": "Lateral femoral cutaneous nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "94b796c1-f291-40f0-9bdf-55e278869b22", "choice_type": "single"} {"question": "The derivative of midgut among the following is", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:188Caecum and appendixThe caecal bud is a diveiculum that arises from the post aerial segment of the midgut Loop. The caecum and appendix are formed by the enlargement of this bud. The proximal pa of the bud grows rapidly to form the caecum. Its distal pa remains narrow and forms the appendix", "cop": 2, "opa": "Rectum", "opb": "Appendix", "opc": "Liver", "opd": "Stomach", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "64907cdc-3ef0-475b-b78b-2633c05c2711", "choice_type": "single"} {"question": "During the active phase of labor the minimum effective dilatation of cervix in primigravida should be at the rate of", "exp": "Effective dilatation of cervix in a primigravida during active phase of labor is 1cm/hr", "cop": 2, "opa": "0.5 cm/hr", "opb": "1cm/hr", "opc": "1.5 cm/hr", "opd": "2 cm/ hr", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "e348b206-4300-4064-9d96-142ad95c4b89", "choice_type": "single"} {"question": "In acute inflammation endothelial retraction leads to", "exp": "ref Robbins 8/e p45,9/ep74 Several mechanisms may contribute to increased vascu- lar permeability in acute inflammatory reactions: * Endothelial cell contraction leading to intercellular gaps in postcapillary venules is the most common cause of increased vascular permeability. Endothelial cell con- traction occurs rapidly after binding of histamine, bra- dykinin, leukotrienes, and many other mediators to specific receptors, and is usually sho-lived (15 to 30 minutes). A slower and more prolonged retraction of endothelial cells, resulting from changes in the cytoskel- eton, may be induced by cytokines such as tumor necro- sis factor (TNF) and interleukin-1 (IL-1). This reaction may take 4 to 6 hours to develop after the initial trigger and persist for 24 hours or more. * Endothelial injury results in vascular leakage by causing endothelial cell necrosis and detachment. Endothelial cells are damaged after severe injury such as with burns and some infections. In most cases, leakage begins immediately after the injury and persists for several hours (or days) until the damaged vessels are throm- bosed or repaired. Venules, capillaries, and aerioles can all be affected, depending on the site of the injury. Direct injury to endothelial cells may also induce a delayed prolonged leakage that begins after a delay of 2 to 12 hours, lasts for several hours or even days, and involves venules and capillaries. Examples are mild to moderate thermal injury, ceain bacterial toxins, and x- or ultraviolet irradiation (i.e., the sunburn that has spoiled many an evening after a day in the sun). Endo- thelial cells may also be damaged as a consequence of leukocyte accumulation along the vessel wall. Activated leukocytes release many toxic mediators, discussed later, that may cause endothelial injury or detachment.", "cop": 3, "opa": "Delayed transient increase in permeability", "opb": "Immediate transient increase in permeability", "opc": "Delayed prolonged increase in permeability", "opd": "Immediate transient decrease in permeability", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "70cd8e61-97f0-490f-989a-2bc4e93fad26", "choice_type": "single"} {"question": "Nerve supply of skin around the umbilicus is", "exp": "A dermatome is an area of skin that is mainly supplied by a single soinal nerve. There are 8 cervical nerves (C1 being an exception with no dermatome), 12 thoraxic nerves, 5 lumbar nerves and 5 sacral nerves. Each of these nerves relays sensation (including pain) from a paicular region of skin to the brain.A dermatome also refers to the pa of an embryonic somite. T10 peains to umblicus Ref - BDC 6e vol2 pg 198-200", "cop": 3, "opa": "T8", "opb": "T9", "opc": "T10", "opd": "T11", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "02ddbda4-21e6-42ae-b368-de97314fe721", "choice_type": "single"} {"question": "Nerve running along with profunda brachii aery, in spiral groove", "exp": "The three nerves related to humerus:-1. Axillary nerve- at surgical neck2. Radial nerve-radial/spiral groove.3. Ulnar nerve-behind medial epicondyle.SPIRAL GROOVE:-Posterior surface of humerus Lodges profunda brachial vessels and radial nerve In the spiral groove, it hives off the following branches:-Lower lateral cutaneous nerve of the arm.Posterior cutaneous nerve of forearm.Nerve to lateral head of triceps.Nerve to medial head of tricepsNerve to anconeus.At the lower end of spiral groove, the nerve pierces lateral muscular septum of the arm and enters anterior compament of the arm.{Reference: Vishram Singh page no.24}", "cop": 3, "opa": "Ulnar", "opb": "Median", "opc": "Radial", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "81dcde4d-3299-4e88-8efd-3da248e794cb", "choice_type": "single"} {"question": "Average time interval between radiation exposure and genesis of post radiation Osteosarcoma", "exp": "Post radiation OGS usually arises after 12-16years Refer post radiation Osteosarcoma", "cop": 4, "opa": "2 yrs", "opb": "4 yrs", "opc": "8 yrs", "opd": "16 yrs", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "ad248d5c-6cdb-4177-958f-90be37976e60", "choice_type": "single"} {"question": "Nerve fibers in greater, lesser and least splanchnic nerves are", "exp": "They also provide the sympathetic innervation to the adrenal medulla, stimulating catecholamine release. The nerve travels inferiorly, lateral to the greater splanchnic nerve. Its fibers synapse with their postganglionic counterpas in the superior mesenteric ganglia, or in the aoicorenal ganglion. image ref- medscape.com", "cop": 1, "opa": "Preganlionic sympathetic", "opb": "Postganglionic sympathetic fibers", "opc": "Postganglionic parasympathetic fibers", "opd": "Postganglionic parasympathetic fibers", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "a4cba0b9-4b4e-47a3-95ed-23075b220c9b", "choice_type": "single"} {"question": "Oblique cord is related to", "exp": "OBLIQUE CORD:-Strong fibrous band which extends from medial side of the tuberosity of ulna to the lower pa of tuberosity of radius.Fibres directed downwards and laterally.i.e, opposite to that of interosseous membrane.Oblique cord between ulnar and radial tuberosities represent degenerated tendon of FPL muscle.{Reference: Vishram Singh, pg no. 145}", "cop": 2, "opa": "Supinator", "opb": "Flexor pollicus longus", "opc": "Flexor digitorum profundus", "opd": "Flexor digitorum superficialis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "15600735-ce2f-4fed-9f94-c55650efee43", "choice_type": "single"} {"question": "Retina develops from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:362", "cop": 1, "opa": "Neural ectoderm", "opb": "Endoderm", "opc": "Surface ectoderm", "opd": "Mesoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bf019d3b-90d2-4812-a8ff-ac10fa6210b2", "choice_type": "single"} {"question": "During Sx for meningioma, the left paracentral lobule was injured. It would lead to paresis of", "exp": "Ans. is 'a' i.e Rt. Leg and perineum Paracentral lobule:On the medial surface of cerebral hemisphere, the U shaped gyrus around the end of the central sulcus is the paracentral lobule.Motor cortex is located in the precentral gyrus on the superolateral surface of the hemisphere and in the anterior part of the paracentral lobule.Stimulation in this area results in movements in the opposite half of the body.The body is represented upside down in this area.A look at the motor homunculus in Ganong will show that the leg and perineum are represented in the paracentral lobule.", "cop": 1, "opa": "Rt. Leg and perineus", "opb": "Left face", "opc": "Right face", "opd": "Right shoulder & trunk", "subject_name": "Anatomy", "topic_name": "Cerebrum", "id": "21ab1846-bbea-4bca-bd03-8933fa61ea5d", "choice_type": "single"} {"question": "Investigation of choice in acute cholecystitis", "exp": "Investigation of choice for acute cholecystitis : USG Gold standard for diagnosis of acute cholecystitis : HIDA scan USG is investigation for acute calculous cholecystitis, chronic cholecystitis and cholelithiasis Ref: Sabiston 20th edition Pgno :1493", "cop": 3, "opa": "OCG", "opb": "HIDA scan", "opc": "USG", "opd": "CT", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8aa41342-16bf-42a0-9871-8f9ba76eb681", "choice_type": "single"} {"question": "Trichology is the forensic examination of", "exp": "Examination of hair(Trichiology) can provide valuable information in crime investigation. forensic trichiology : The first step of forensic identification and comparison of hairs begins with whole mount light microscopy. The hair(s) in question must be identified as to species, race and body (somatic) origin. Human hairs can be readily distinguished from animal hairs in primarily by examining the cuticles and medullae .Individualizing human hairs is done by examining coex features and by analyzing DNA. Forensic laboratory repos of hair comparisons normally will provide one of three answers: The hairs matched in microscopic characteristics, indicating an association. The hairs are not alike and therefore did not come from the same person. No conclusion can be drawn from the evidence. This may be due to insufficient specimen, racial mixtures, or unsuitable exemplars. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE No 107", "cop": 1, "opa": "Hair", "opb": "Finger nails", "opc": "Skin", "opd": "Lip prints", "subject_name": "Anatomy", "topic_name": null, "id": "3f3a9199-fe03-409f-80e7-35d5616705a9", "choice_type": "single"} {"question": "At the end of 8th month, testes descend into", "exp": "C i.e. Scrotum", "cop": 3, "opa": "Superficial inguinal ring", "opb": "Inguinal canal", "opc": "Scrotum", "opd": "Deep inguinal ring", "subject_name": "Anatomy", "topic_name": null, "id": "04ca8004-c91d-4c4d-9df4-52c7ad846d4a", "choice_type": "single"} {"question": "Foot drop results as a result of injury to", "exp": "FOOT DROP:- Paralysis of muscles of anterior compament of the leg due to injury to deep peroneal nerve results in loss of power of dorsiflexion of foot and eversion. As a result, foot us plantar flexed. Ankle reflex is intact.This is usually caused by injury or disease of the common peroneal nerve due to trauma, leprosy or peripheral neuritis.Sensory loss- first interdigital cleft. {Reference: BDC 6E pg no.97}", "cop": 1, "opa": "Deep peroneal nerve", "opb": "Superficial peroneal nerve", "opc": "Tibial nerve", "opd": "Deltoid ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "a6c3571c-1614-49cd-bd31-e7b8a9657ad0", "choice_type": "single"} {"question": "Most common lesion assoasiated with pathological fractures in hand is", "exp": "Majority of the pathological fractures are caused by Enchondromas Refer Management of hand fractures", "cop": 1, "opa": "Enchondroma", "opb": "Metastases", "opc": "Osteoid sarcoma", "opd": "Osteochondroma", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "af090e7d-44ed-46be-bc6f-faefcc9505b4", "choice_type": "single"} {"question": "Bui,opliao ligLal membrane develops froui.", "exp": "Ans. b. Ectoderm + Endoderm", "cop": 2, "opa": "Ectoderm + Mesoderm", "opb": "Ectoderm + Endoderm", "opc": "Mesoderm + Endoderm", "opd": "Ectoderm + Mesoderm + Endoderm", "subject_name": "Anatomy", "topic_name": null, "id": "b0d19b4e-94a6-401c-a875-a460c52d6d28", "choice_type": "single"} {"question": "C_C beta chemokines includes", "exp": "Ref ,Robbins 8/e 62-63 ,7/e p71; 9/e p87 The eotaxins are a CC chemokine subfamily of eosinophil chemotactic proteins. In humans, there are three family members: CCL11 (eotaxin-1) CCL24 (eotaxin-2) CCL26 (eotaxin-3)", "cop": 2, "opa": "Il_8", "opb": "Eotaxin", "opc": "Lymphotactin", "opd": "Fractalkine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4b030965-903c-4f39-8560-0ba3c3268fbd", "choice_type": "single"} {"question": "Advantage of contact lens over normal glasses;", "exp": "Advantages: Less magnification (5%) of the image, elimination of aberrations and prismatic effect of thick glasses wider and better field of vision, cosmetically better accepted by young persons. Disadvantages: more cost, cumbersome to wear, especially in old age and in childhood, corneal complications may occur (Inflammation/ Infection).", "cop": 1, "opa": "Prismatic effect will less", "opb": "Prevention from UV rays", "opc": "Decrease inflammation", "opd": "Decrease infection", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "ff7effb5-c9a2-4949-8a80-2976b893525c", "choice_type": "single"} {"question": "Adverse effects that limit the use of adrenoceptors blockers include", "exp": "Ref-KDT 6/e p142 Beta blockers are contraindicated in acute CHF because this can exacterbate with the hea failure. Bronchoconstriction And impairment of blood glucose response is seen with beta blockers. This agents also decreases intraocular pressure and are used for the treatment of glaucoma.", "cop": 2, "opa": "Bronchoconstriction from alpha blocking agents", "opb": "Hea failure exacerbation from beta blockers", "opc": "Impaired blood sugar response with alpha blockers", "opd": "Increased intraocular pressure with beta blockers", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "c47b1345-78d4-45eb-970d-7d1398758978", "choice_type": "single"} {"question": "Auto immunity in EBV infection is the result of", "exp": "Ref Robbins 8/e p212; 9/e p216 Infection with Epstein-Barr virus (EBV), the cause of infectious mononucleosis, has been associated with subsequent development of systemic lupus erythematosus and other chronic autoimmune illnesses It is due to PolyclonalB B cell proliferation and activation", "cop": 2, "opa": "Molecular mimicry", "opb": "PolyclonalB cell activation", "opc": "Expressing sequestered antigen", "opd": "Antigenic cross reactivity", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b4e58d07-539c-4e88-a33b-2da4fd37cc75", "choice_type": "single"} {"question": "Mucos membrane of vagina is lined by", "exp": "VAGINA HISTOLOGY Mucos membrane lining: Nonkeratinized Stratified Squamous epithelium Lamina propria: Loose connective tissue Muscle coat Fibrous coat: Connective tissue There are NO GLANDS in vaginal mucosa Vaginal fluid in acidic: Due to glycogen-fermentation by Doderlein's bacilli", "cop": 1, "opa": "Nonkeratinized Stratified Squamous epithelium", "opb": "Keratinized Stratified Squamous epithelium", "opc": "Columnar cells", "opd": "Cuboidal epithelium", "subject_name": "Anatomy", "topic_name": "Epithelial tissue", "id": "5791182f-9e6b-4a69-8f48-941138b36c99", "choice_type": "single"} {"question": "Stratum germinativum is synonymous to", "exp": "Stratum basale:\n\nAlso called stratum germinativum.\nMade of single layer of columnar epithelium.\nContains keratinocytes and melanocytes.", "cop": 1, "opa": "Stratum Basale", "opb": "Stratum Spinosum", "opc": "Stratum granulosum", "opd": "Stratum corneum", "subject_name": "Anatomy", "topic_name": null, "id": "778c96a7-6f33-495d-be30-2036f4d9a53b", "choice_type": "single"} {"question": "The basis of combining Ritonavir with Lopinavir", "exp": "Refer Katzung 10/e p810 Ritonavir is a microsomal enzyme inhibitor paicularly of CYP3A4 .it decreases the metabolism of other drugs and thus lower dose of Lopinavir can be used in treatment of HIV when combined with Ritonavir", "cop": 2, "opa": "Pharmaceutical compatability", "opb": "CYP3A4 inhibiton NY Ritonavir", "opc": "Long elimination half life of Ritonavir", "opd": "Ability to counteract side effects of Lopinavir", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5a727237-7a4d-4aa0-85bc-ff45473cbfc2", "choice_type": "single"} {"question": "Paranoid pseudocommunity was given by", "exp": "o Norman Cameron====== paranoid pseudocommunity SS Patient incorporates all the people who are against her thoughts as working together and are against her SS Community which is false(pseudo) and that is against(paranoid) the patient ref.Kaplon and Sadock, synopsis of psychiatry, pg no 335", "cop": 1, "opa": "Norman camerron", "opb": "ku schneider", "opc": "Benedict morel", "opd": "Eugene Bleuler", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "18d3fed6-a1b8-498a-9585-d3b21da47ce9", "choice_type": "single"} {"question": "Ganciclovir is preferred over acyclovir in the following condition", "exp": "Ref-KDT 6/e p769 Ganciclovir is the drug of choice for CMV infections. Acyclovir is highly effective against Herpes simplex and Varicellal zoster (chicken pox and herpes zoster) but it has very little activity against CMV.", "cop": 4, "opa": "Herpes simplex keratitis", "opb": "Herpes zoster", "opc": "Chicken pox", "opd": "Cytomegalovirus retinitis in AIDs patients", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "58d8d78e-278e-4db4-8b33-abf9b76c5c24", "choice_type": "single"} {"question": "T.B. testis first affects", "exp": "The disease first affects the epididymis. The body of testis may remain uninvolved for years, but the contra lateral epididymis often becomes diseased. Treatment is - ATT if ds. does not resolve, epididymectomy or orchidectomy is indicated. Ref : Bailey & Love 25/e p1383", "cop": 2, "opa": "Vas", "opb": "Epididymis", "opc": "Body of testis", "opd": "Tunica vaginalis", "subject_name": "Anatomy", "topic_name": "Urology", "id": "ef6e57ad-38c1-4193-a2d1-78119cad927c", "choice_type": "single"} {"question": "Opening in prostatic sinus is", "exp": "Vesiculae seminales and ampulla of ductus deferens, seen from the front. Dissection of the prostate showing the prostatic urethra. The prostatic ducts are seen opening into the prostatic sinus, which lies on either side of the urethral crest and seminal colliculus. ref - BDC vol2 pg 401-404 , semantischolar.org", "cop": 4, "opa": "Seminal vesicle", "opb": "Ejaculatory ducts", "opc": "Prostatic utricle", "opd": "Prostatic ductules", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "f217aade-d684-40b6-9d47-698482e79734", "choice_type": "single"} {"question": "Subarachnoid block as anaesthesia is contraindicated in", "exp": "Worried about epidural hematoma", "cop": 1, "opa": "Haemophilia", "opb": "Burgers disease", "opc": "Atherosclerotic gangrene", "opd": "Full stomach", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "49fdab7a-f77d-4e97-9520-bd1a6839bfa4", "choice_type": "single"} {"question": "Chief extensor of knee joint in hip flexion is", "exp": "A. i.e. Rectus femoris", "cop": 1, "opa": "Rectus femoris", "opb": "Vastus medialis", "opc": "Vastus latralis", "opd": "Hamstrings", "subject_name": "Anatomy", "topic_name": null, "id": "2c798e94-b6de-4cc7-9f2c-50efbb783f84", "choice_type": "single"} {"question": "Mucous glands are absent in", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:359 Vagina Mucous membrane The epithelium rests on dense connective tissue that is highly vascular,many veins being present .the tissue is rich in elastic fibres.no glands are seen in the mucosa,the vaginal surface being kept moist by the secretions if glands in the cervix of the uterus", "cop": 3, "opa": "Cervix", "opb": "Esophagus", "opc": "Vagina", "opd": "Duodenum", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7e0d39b1-8388-480b-87f3-017d5d427558", "choice_type": "single"} {"question": "glomus tumor is seen", "exp": "Glomus tumor is biologically a benign tumor that arises from the modified smooth muscle cells of the glomous body Glomus body is a specialised aeriovenous anastomosis that is involved in thermoregulation It is a often painful tumor Glomus tumor are most commonly found in distal poion of the digits especially under fingernails Excision is curative Refer robbins 9/e p517", "cop": 3, "opa": "Retroperitonium", "opb": "Soft tissue", "opc": "Distal poion of digits", "opd": "Proximal poion of digits", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "d7936338-7f29-49f6-b2da-8a4514c60751", "choice_type": "single"} {"question": "Reconstructive surgery for Choledochal cyst is not done in", "exp": "According to Todani Modification of Alonso-Lej classification Type III : is Cystic dilation of intra duodenal poion of common bile duct (choledochocele) Treatment : Endoscopic sphincterectomy and cyst unroofing Ref: Sabiston 20th edition Pgno :1510-1511", "cop": 3, "opa": "Type I", "opb": "Type II", "opc": "Type III", "opd": "Type IV", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3f83b974-61d7-4cb7-a00e-2e18b8daeaac", "choice_type": "single"} {"question": "Obsession is a disorder of thought", "exp": "obsession is a disorder of thought possession the very impoant question that is asked under the subject of psychiatry is regarding obsession the impoant qualities of obsession that as to be taken from the case scenario related questions are RECCURRENT IRRELEVANT INTRUSIVE IRRESSISTABLE DISTRESSING EGO DYSTONIC THOUGHTS. Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg.192", "cop": 4, "opa": "Content", "opb": "Perception", "opc": "stream", "opd": "possession", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "633b445f-c568-41ee-b566-264a8c8ed219", "choice_type": "single"} {"question": "Asymptomatic, solid 4cm tumor of distal pancreas. Treatment", "exp": "Resectional Surgery for pancreatic Body and Tail Tumors Most body and tail cancers have already metastasized to distant sits or extended locally to involve nodes, nerves or major vessels by the time of diagnosis Splenic vein involvement or occlusion is not a sign of nonresectability Involvement of the splenic and SMV confluence generally precludes resection Resection involves a distal pancreatectomy either with or without concomitant splenectomy Splenectomy is usually performed with distal pancreatectomy in patients suspected of having carcinoma to obtain better margins, to remove the lymph nodes at the tip of the pancreas and hilum of the spleen, and to avoid tedious dissection of the splenic aery and vein Ref: Sabiston 20th edition Pgno :1547", "cop": 4, "opa": "Observation", "opb": "Distal pancreatectomy with splenectomy", "opc": "Near total pancreatectomy with splenectomy", "opd": "Distal pancreatectomy alone", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "034fae71-2212-45fb-b00c-97b63349d108", "choice_type": "single"} {"question": "Esophagus enters abdomen through", "exp": "Oesophageal opening\n-        Level- T10\n-        At muscular portion derived from right crus\n-        Structures transmitted\n\n  Oesophagus\n  Oesophageal branch of left gastric artery\n  Vagus nerve", "cop": 3, "opa": "Central tendon of diaphragm", "opb": "Along aortic opening", "opc": "Muscular part of diaphragm", "opd": "Right crus", "subject_name": "Anatomy", "topic_name": null, "id": "a283ed15-4339-4c4d-9967-0b3ab4006e6e", "choice_type": "single"} {"question": "Crossed occulomotor palsy is seen in occlusion of", "exp": "A. i.e. Posterior cerebral aery", "cop": 1, "opa": "Post. Cerebral a", "opb": "Middle cerebral a", "opc": "Ant. Cerebral a", "opd": "Superior cerebellar a", "subject_name": "Anatomy", "topic_name": null, "id": "963bb2e4-6612-4ad0-bc36-0506915d3f88", "choice_type": "single"} {"question": "Type of Collagen in Hyaline Cartilage is", "exp": "Types of Collagen in different tissues\nType I - Bone, skin\nType II - Hyaline and elastic Cartilage\nType III - Skin, ligament, blood vessels\nType IV - Basement membrane in various tissue\nType V - Blood vessel wall, Synovium, corneal stroma", "cop": 2, "opa": "Type I", "opb": "Type II", "opc": "Type III", "opd": "Type IV", "subject_name": "Anatomy", "topic_name": null, "id": "5184ba3a-2c28-4c94-a11d-9548ae8b822d", "choice_type": "single"} {"question": "Muscle spared in Lateral epicondyle fracture", "exp": "Nerve supply to Extensor carpi radialis longus is given before the redial nerve reaches lateral epicondyle.", "cop": 4, "opa": "Extensor digitorum", "opb": "Extensor pollicis longus", "opc": "Extensor carpi radialis brevis", "opd": "Extensor carpi radialis longus", "subject_name": "Anatomy", "topic_name": null, "id": "90fa5c61-10cd-47e2-b166-d9146673d9bf", "choice_type": "single"} {"question": "Root of mesentery doesn't cross the following", "exp": "The mesentery of the small intestine arises from the root of the mesentery and is the pa connected with the structures in front of the veebral coloumn. The root is narrow and is directed obliquely from the duodenojejunal flexure at the left side of the second lumbar veebrae to the right sacroiliac aiculation. The root of the mesentery extends from the duodenojejunal flexure to the ileocaecal junction. This section of the small intestine is located centrally in the abdominal cavity and lies behind the transverse colon and the greater omentum. Structures passed by root of mesentry ref - BDC 6e vol2 pg235", "cop": 4, "opa": "Right ureter", "opb": "Abdominal aoa", "opc": "Inferior vena cava", "opd": "Second pa of duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fc9abb14-9546-4680-82e0-a933d20acfb0", "choice_type": "single"} {"question": "steven johnsons syndrome is a side effect of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential Ref.kaplon and sadock, synopsis of psychiaty, 11 th edition, pg no.923", "cop": 1, "opa": "carbamezepine", "opb": "lithium", "opc": "clozapine", "opd": "clonazepam", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "98e35668-1f36-4dc1-97b2-3b91c4ad4b92", "choice_type": "single"} {"question": "The joint between the attachment of the 8th and the 9th rib to the 7th rib is a", "exp": "The joint between the attachment of the 8th and 9th rib with the 7th rib is a synol joint. Most of the joints in the thoracic cavity- Interchondral, sternochondral, costoveebral and costotransverse joints, are plain synol joints because the thoracic cavity needs to expand during inspiration. The exception are : 1st sternocostal joint: Synahrosis (fibrous) Interchondral joint between the 9th and 10th cailages is never synol and sometimes absent. Costochondral joints are primary cailaginous joints (Synchondrosis) Midline joints like manubriosternal and xiphisternal joints are secondary cailagenous joints of symphysis type. Ref: Gray&;s Anatomy 41st edition Pgno: 940", "cop": 3, "opa": "Fibrocailaginous joint", "opb": "Symphyseal joint", "opc": "Synol joint", "opd": "Fibrous joint", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "de7dfd46-f2fb-47f2-9480-ab04bdee63fd", "choice_type": "single"} {"question": "Migratory thrombophlebitis is seen in", "exp": "Malignancies associated with Migratory thrombophlebitis CA pancreas(MC) CA lung GI malignancies Prostate cancer Ovarian cancer Lymphoma Troesseau's syndrome : Migratory thrombophlebitis Ref: Robbins 9tu edition Pgno :332,126", "cop": 1, "opa": "Pancreatic cancer", "opb": "Bladder cancer", "opc": "Breast cancer", "opd": "Liver cancer", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7edc45b8-e5f5-4f93-8234-6f80407b936a", "choice_type": "single"} {"question": "Enzymes found in CSF", "exp": "The diagnostic value of cerebrospinal fluid (CSF) enzyme activities in neurological disorders has been evaluated most extensively with the enzymes aspaate aminotransferase (ASAT), lactate dehydrogenase (LDH), creatine kinase (CK) and lysozyme Refer Robbins page no chatteejee shinde 8th/730", "cop": 3, "opa": "GGT+ALP", "opb": "ALP+CK-MB", "opc": "CK +LDH", "opd": "Deaminase and peroxidase", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "2ba75207-9440-4fbd-a656-1ba83e100a42", "choice_type": "single"} {"question": "Regula vein, aery and nerve (\"VAN\") arrangement", "exp": "BD CHAURASIA S HUMAN ANATOMY Vol1 Pg 222 Sixth edition The general arrangement of first intercostal space is vein,aery and nerve(VAN)", "cop": 1, "opa": "First intercostal space", "opb": "Second intercostal space", "opc": "Third intercostal space", "opd": "Eleventh intercostal space", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a9f90604-24b2-4e56-a739-660d186ab6b4", "choice_type": "single"} {"question": "Blood supply to middle third of vagina is", "exp": "Blood is supplied to the vagina by the uterine and vaginal aeries, both branches of the internal iliac aery. Venous return is achieved by the vaginal venous plexus, which drains into the internal iliac veins, the uterine vein. Lymphatic drainage is the iliac and superficial inguinal lymph nodes. ref - BDC 6e vol2 pg394", "cop": 4, "opa": "Middle rectal aery", "opb": "Inferior vesicle aery", "opc": "Internal pudendal aery", "opd": "Central vaginal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "4ec83245-2e4c-4ab2-8ef0-64962711f771", "choice_type": "single"} {"question": "Not a pa of bony labyrinth", "exp": "BONY LABYRINTH:The bony labyrinth consists of three pas(a)Cochlea anteriorly (b)Vestibule,in the middle (c)Semicircular canals posteriorly REF.,BDC VOL.3", "cop": 3, "opa": "Cochlea", "opb": "Vestibule", "opc": "Utricle", "opd": "Semicircular canal", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "cc5eba50-ad47-4a99-a074-9f0f20112a53", "choice_type": "single"} {"question": "Circle of willis is formed by", "exp": "Middle cerebral artery doesn’t form circle of willis.", "cop": 4, "opa": "Anterior cerebral artery, posterior communicating artery, middle cerebral artery, posterior cerebral artery, internal carotid artery", "opb": "Anterior cerebral artery, posterior communicating artery, internal carotid artery, anterior communicating artery, middle cerebral artery.", "opc": "Anterior communicating artery, posterior communicating artery, internal carotid artery, anterior inferior cerebellar artery, anterior cerebral artery.", "opd": "Anterior communicating artery, posterior communicating artery, internal carotid artery, posterior cerebral artery, anterior cerebral artery.", "subject_name": "Anatomy", "topic_name": null, "id": "0e625181-2793-496c-a54b-553cfb581d6d", "choice_type": "single"} {"question": "Dermatomal distribution of gluteal fold is through", "exp": "Dermatomal distribution of gluteal fold is through s3. BD CHAURASIA S HUMAN ANATOMY SIXTH Edition Pg no 66", "cop": 4, "opa": "L1", "opb": "L3", "opc": "S1", "opd": "S3", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a2ba9aef-f09b-43c3-b20c-b2972d33da2c", "choice_type": "single"} {"question": "assosiated with anorexia nervosa is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "obesity", "opb": "ECG changes", "opc": "over weight", "opd": "metabolic syndrome", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "e9ca3228-3306-4e0d-9170-93c265ee36c3", "choice_type": "single"} {"question": "Type of anemia caused by ileoceacal TB is", "exp": "In intestinal tuberculosis the ileoceacal junctioj6is the commonest site of involvement. Ileum is the physiological site for absorption of vitaminB12 also TB is mentioned to be a cause of holi acid deficiency which is therefore going to result in Megaloblastic anemia Refer Harrison 17th/649", "cop": 2, "opa": "Iron deficiency", "opb": "Megaloblastic", "opc": "Sideroblastic", "opd": "Normocytic normochromic", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "52ff6a72-13ce-4cd1-9f13-c982707835e0", "choice_type": "single"} {"question": "The growth and development in the craniofacial region occurs in following order", "exp": null, "cop": 1, "opa": "The head first, then width of face and length (or) depth of face after wards", "opb": "the width of face, then head and length (or) depth of face after wards", "opc": "The length (or) depth of face then width of face and the head", "opd": "The head first, length (or) depth of face and then width of face", "subject_name": "Anatomy", "topic_name": null, "id": "8cbdcc0a-818c-49c9-b650-b16126941652", "choice_type": "single"} {"question": "Post traumatic osteomyelitis causing organism is", "exp": "Staphylococcus aureus is the most common causative organism in all age groups. Salmonella is the commonest organism in sickle cell anemia patients(diaphyseal). Psuedomonas aeruginosa is the commonest organism in drug abusers. ref : maheswari 9th ed", "cop": 1, "opa": "Staphylococcus aureus", "opb": "Staphylococcus pyogenes", "opc": "E.coli", "opd": "Pseudomonas", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "868b45c3-2538-4950-b765-481285472ee3", "choice_type": "single"} {"question": "Oligodendrocytes are impoant in", "exp": "Oligodendrocytes:According to their distribution they may be of intrafscicular,or perineural. The intrafascicular cells are found in the myelinated tracts.The perineuronal cells are seen on the surface of the somata of the neurons. REF.BDC Handbook of general anatomy,4th edition", "cop": 1, "opa": "Myelin formation", "opb": "Blood brain barrier", "opc": "Phagocytosis", "opd": "Collagen synthesis", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "a2315585-8748-4858-b79f-de5e2837a383", "choice_type": "single"} {"question": "The boundary of the triangle of auscultation is not formed by", "exp": "Triangle of auscultation is bounded medially by the lateral border of the trapezius, laterally by scapula and inferiorly by lattismus dorsi", "cop": 1, "opa": "Serratus anterior", "opb": "Scapula", "opc": "Trapezius", "opd": "Latissimus dorsi", "subject_name": "Anatomy", "topic_name": null, "id": "401eec78-4a93-4cad-a1f6-4562238262e3", "choice_type": "single"} {"question": "Strongest sutural joint among the following", "exp": "Lambdoid suture is a dentianlate suture joint which is strongest among the given options.", "cop": 2, "opa": "Coronal Suture", "opb": "Lambdoid suture", "opc": "Interpalatine suture", "opd": "Temporaparietal suture", "subject_name": "Anatomy", "topic_name": null, "id": "b75db6f1-595b-4b8c-bc0c-2e358eb57c8c", "choice_type": "single"} {"question": "Crookes hyaline body is present in", "exp": "In Cushing syndrome, the normal granular,basophillic cytoplasm of the ACTH producing cells in the anterior pituitary becomes parlor and homogeneous . This is due to accumulation of intermediate keratin filaments in cytoplasm", "cop": 3, "opa": "A. Yellow fever", "opb": "B. Parkinsonism", "opc": "C. Basophill cells of pituitary gland in Cushing syndrome", "opd": "D. Huntington disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ff5fbeb1-68c3-4098-8e39-986ba35e2f71", "choice_type": "single"} {"question": "The type of joint present between ear ossicles is", "exp": "JOINTS OF EAR OSSICLES The incudomalleolar joint is a saddle joint. The incudostapedial joint is a ball and socket joint. Both of them are type of synol joints. Ref BDC volume 3,sixth edition pg 280", "cop": 3, "opa": "Primary cailaginous", "opb": "Secondary cailaginous", "opc": "Synol", "opd": "Fibrous", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9dfe04c6-ea9e-4afb-9166-5af1518f9349", "choice_type": "single"} {"question": "Notochord develops by", "exp": "(C) 14-21 days post conception [Grays40-184; IBS7-47# Genesis of the notochord:> Notochord develops in 3rd week.> Around the 19th day cells that invade into the primitive node region & migrate along the median line cranially from the chordal process (also known as the axial process).> On the 25th day 9 the chordal plate cuts itself off from the endoderm, which then fuses again, & forms a complete cord:# Notochord:> This is in the middle of the mesoderm, between the ectoderm and endoderm, & plays a role in the induction of the neuro ectoblast that lies over it.> Notochord plays a role in the genesis of the vertebral body & becomes the nucleus pulposus in the intervertebral disk", "cop": 3, "opa": "8 weeks of pregnancy", "opb": "24 weeks of pregnancy", "opc": "14-21 days post conception", "opd": "2 weeks post conception", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "fdd665c5-47a1-4129-bf6b-1d7db74141c7", "choice_type": "single"} {"question": "Floor of posterior triangle of neck is formed by", "exp": "Muscles forming floor of posterior triangle of neck :\n\n Semispinalis capitis.\n Splenius capitis.\n Levator scapulae.\n Scalenus posterior.\n Scalenus medius.", "cop": 4, "opa": "Semispinalis capitis, elevator scapulae, scalenus anterior, scalenus medius", "opb": "Levator scapulae, splenius capitis, scalenus medius, scalenus anterior", "opc": "Semispinalis capitis, scalenus anterior, splenius capitis, sternocleidomastoid", "opd": "Levator scapulae, scalenus posterior, semispinalis capitis,scalenus medius", "subject_name": "Anatomy", "topic_name": null, "id": "7fdd8ca0-7113-4ce7-be6c-2c03f286b0fc", "choice_type": "single"} {"question": "Foot eversion is caused by (FMGE Dec 2018)", "exp": "Also known as FIBULARIS LONGUS. It is muscle of lateral compament of leg. ORIGIN: Upper 2/3rd of lateral surface of fibula, head of fibula & occasionally lateral tibial condyle. INSEION: Undersurface of lateral sides of distal end of medial cuneiform & base of metatarsal I. INNERVATION: Superficial fibular nerve (L5, S1, s2) Function: eversion & plantar flexion of foot, suppo arches of foot. Muscle Origin Inseion Innervation Function a) extensor digitorum longus | anterior compament of leg. Proximal 1/2 of medial surface of fibula & related surface of lateral tibial condyle. Via dorsal digital expansions into bases of distal & middle phalanges of lateral 4 toes. Deep fibular nerve (L5, S1) Extension of lateral 4 toes & dorsiflexion of foot b) tibialis anterior | anterior compament. Lateral surface of tibia & adjacent interosseous membrane. Medial & inferior surface of medial cuneiform & adjacent surface on base of metatarsal I. Deep fibular nerve (L4, L5) Dorsiflexion of foot at ankle joint, inversion of foot, dynamic suppo of medial arch of foot c) tibialis posterior | posterior compament of leg Posterior surfaces of interosseous membrane & adjacent regions of tibia & fibula Mainly to tuberosity of navicular & adjacent region of medial cuneiform Tibial nerve (L4, L5) Inversion & plantar flexion of foot, suppo medial arch of foot while walking.", "cop": 2, "opa": "Extensor digitorum", "opb": "Peroneus longus", "opc": "Tibialis anterior", "opd": "Tibialis posterior", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "995cf40c-296e-46a2-897c-7b44ace7e0ef", "choice_type": "single"} {"question": "Predisposing factors for skin cancer are", "exp": "Ref Robbins 9/e p1155; Harrison 16/e p497 Uvrays and chronic ulcer are also the answers proliferation. Dysplasia is encountered principally in epi- thelial lesions. It is a loss in the uniformity of individual cells and in their architectural orientation. Dysplastic cells exhibit considerable pleomorphism and often possess hyperchro- matic nuclei that are abnormally large for the size of the cell. Mitotic figures are more abundant than usual and frequently appear in abnormal locations within the epithe- lium. In dysplastic stratified squamous epithelium, mitoses are not confined to the basal layers, where they normally occur, but may be seen at all levels and even in surface cells. There is considerable architectural anarchy. For example, the usual progressive maturation of tall cells in the basal layer to flattened squames on the surface may be lost and replaced by a disordered scrambling of dark basal- appearing cells (Fig. 5-6). When dysplastic changes are marked and involve the entire thickness of the epithelium, the lesion is referred to as carcinoma in situ, a preinvasive stage of cancer (Chapter 18). Although dysplastic changes often are found adjacent to foci of malignant transforma- tion, and long-term studies of cigarette smokers show that epithelial dysplasia almost invariably antedates the appear- ance of cancer, the term dysplasia is not synonymous with cancer; mild to moderate dysplasias that do not involve the entire thickness of the epithelium sometimes regress completely, par- ticularly if inciting causes are removed. Clinical Features Although most of these lesions arise in the skin, they also may involve the oral and anogenital mucosal surfaces, the esophagus, the meninges, and the eye. The following com- ments apply to cutaneous melanomas. Melanoma of the skin usually is asymptomatic, although pruritus may be an early manifestation. The most impoant clinical sign is a change in the color or size of a pigmented lesion. The main clinical warning signs are 1. Rapid enlargement of a preexisting nevus 2. Itching or pain in a lesion 3. Development of a new pigmented lesion during adult life 4. Irregularity of the borders of a pigmented lesion 5. Variegation of color within a pigmented lesion These principles are expressed in the so-called ABCs of melanoma: asymmetry, border, color, diameter, and evolu- tion (change of an existing nevus). It is vitally impoant to recognize melanomas and intervene as rapidly as pos- sible. The vast majority of superficial lesions are curable surgically, while metastatic melanoma has a very poor prognosis. The probability of metastasis is predicted by measuring the depth of invasion in millimeters of the veical growth phase nodule from the top of the granular cell layer of the overlying epidermis (Breslow thickness). Metastasis risk also is increased in tumors with a high mitotic rate and in those that fail to induce a local immune response. When metastases occur, they involve not only regional lymph nodes but also liver, lungs, brain, and viually any other site that can be seeded hematogenously. Sentinel lymph node biopsy (of the first draining node of a primary melanoma) at the time of surgery provides additional information on biologic aggressiveness. In some cases, metastases may appear for the first time many years after complete surgical excision of the primary tumor, suggesting a long phase of dormancy, during which time the tumor may be held in check by the host immune response. Recognition of the likely role of the host immune response has led to therapeutic trials of immunomodula- tors. Some impressive responses in patients with advanced", "cop": 1, "opa": "Smoking", "opb": "Uv light", "opc": "Chronic ulcer", "opd": "Infrared light", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "60a6bb21-3fad-4610-8837-1bf61a784488", "choice_type": "single"} {"question": "Roof of the Anatomical snuff box is formed by the", "exp": "Anatomical snuff box boundaries: Lateral wall Abductor pollicis longus Extensor pollicis brevis Medial wall Extensor pollicis longus Roof Cephalic vein Sup branch of radial nerve Floor Radial styloid, scaphoid, trapezium,1st meta carpal Content Radial Aery Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 893.", "cop": 3, "opa": "Radial aery", "opb": "Basilic aery", "opc": "Sup branch of radial nerve", "opd": "Sup branch of ulnar nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "088e94f6-ca40-4fef-9eac-904fd15c4ef9", "choice_type": "single"} {"question": "Origin of maxillary artery", "exp": null, "cop": 1, "opa": "Neck of condyle.", "opb": "Angle of mandible.", "opc": "Body of mandible.", "opd": "Coronoid process", "subject_name": "Anatomy", "topic_name": null, "id": "b07990af-fdf8-4830-aeba-9f40479704a9", "choice_type": "single"} {"question": "Enzyme not involved in DNA replication is", "exp": "Enzymes required for ReplicationEnzymes involved in DNA replicationDescriptionHelicase Unwinding of DNA in 5' to 3' direction preceding replication forks Topoisomerase Relieves torsional strain that results from helicase induced unwinding DNA primase Initiates synthesis of RNA primers DNA polymerase Enzymes derived from RNA tumor viruses that make complementary DNA copies from RNA templates Restriction endonuclease Cut DNA into fragments at specific DNA sequences DNA ligase Seals the breaks between nascent chain and Okazaki fragments DNA gyrase Introduce negative supercoils into resting DNA (Refer: Harper's Illustrated Biochemistry, 26th edition, pg no: 328, table 36-5)", "cop": 2, "opa": "Telomerase", "opb": "Reverse transcriptase", "opc": "Restriction endonuclease", "opd": "DNA ligase", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c39a97b9-7122-4ee7-a7a1-b6cc8d0051d8", "choice_type": "single"} {"question": "The ventral surface of the adult hea as seen on gross examination or radiography is comprised primarily of the", "exp": "Ventral surface(sternocostal surface) of hea is contributed by - 2/3rd of right ventricle (major contributor) 1/3rd of left ventricle Right atruim and left auricle. During embryological formation of the hea, the aerial and venous ends of the hea tube are fixed in place. As fuher growth continues, the hea tube folds to the right. This greatly contributes to the ventral surface of the adult hea being comprised primarily of the right ventricle.", "cop": 4, "opa": "Left atrium", "opb": "Left ventricle", "opc": "Inferior vena cava", "opd": "Right ventricle", "subject_name": "Anatomy", "topic_name": "CVS Embryology", "id": "9820e7b3-691a-4a97-bea2-b53865ae7fdf", "choice_type": "single"} {"question": "Lamina papercea separates nose from", "exp": "Ans. is 'b' i.e., Orbit The lamina papyracea is a thin pa of ethmoid.The bone lamina papyracea divides the orbit from the nose and paranasal sinuses. The orbit and the paranasal sinuses are intimately related on three sides.The lamina papyracea separates the orbit and its contents from the ethmoidal sinus.Lamina papyracea aiculates :-Above with orbital plate of frontal bone.Below with maxilla and orbital process of palatine bone.In front with lacrimal boneBehind with sphenoid.Lamina papyracea is so called as it is paper thin and fractures easily.Fracture may cause entrapement of medial rectus.", "cop": 2, "opa": "Sphenoid bone", "opb": "Orbit", "opc": "Frontal bone", "opd": "Maxillary sinus", "subject_name": "Anatomy", "topic_name": null, "id": "634d430d-b146-42ce-a777-b430c4df63c6", "choice_type": "single"} {"question": "Pathological gambling is included in DSM 5 under", "exp": "GAMBLING DISORDER * IMPOANCE===Newly classified in DSM 5 substance use and addictive disorders * MAIN CHARECTERSTICS==Lying to conceal the extent of involvement of gambling * Commission of illegal acts to finance gambling Reliance on others to pay off debts Ref. Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no.690", "cop": 3, "opa": "impulse control disorder", "opb": "obsessive compulsive disorder", "opc": "substance use disorder", "opd": "shared psychotic disorder", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f4073b2d-a1bf-4dff-904d-4bf577aecb85", "choice_type": "single"} {"question": "Most commonly affected peripheral nerve in leprosy is", "exp": "Although any peripheral nerve may be enlarged (including small digital and supraclavicular nerves), those most commonly affected are the ulnar, posterior auricular, peroneal, and posterior tibial nerves, with associated hypesthesia and myopathy. Ref : Harrison 17/e p1022", "cop": 1, "opa": "Ulnar", "opb": "Radial", "opc": "Median", "opd": "Popliteal", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9817f73e-eb67-403d-a5e8-45d56e58dddc", "choice_type": "single"} {"question": "Primary sinusoidal dilation of liver is also known as", "exp": "Hepatic sinusoidal dilatation refers to the enlargement of the hepatic capillaries. Most of the time this condition is caused by hepatic venous outflow obstruction, which results in vascular stasis and congestion of hepatic parenchyma. In this setting, hepatic sinusoidal dilatation can be related to pericardial disease, hea failure, compression or thrombosis of the hepatic veins or inferior vena cava (i.e., Budd-Chiari syndrome) or central veins/sinusoids involvement (i.e., sinusoidal obstruction syndrome). Neveheless, some extrahepatic inflammatory conditions (such as pyelonephritis, cholecystitis, pneumonia, pancreatitis, intestinal bowel disease, and others) may be associated with hepatic sinusoidal dilatation without concurrent venous outflow obstruction. On contrast-enhanced cross-sectional imaging, hepatic sinusoidal dilatation is typically characterized by a mottled, reticular enhancement of the liver, usually referred to as \"mosaic\" pattern. Other hepatic and extrahepatic imaging features, such us the dilatation of the hepatic veins or the presence of ascites, can help in identifying the cause of sinusoidal dilatation. ref - pubmed.com", "cop": 2, "opa": "Hepar lobatum", "opb": "Pellosis hepatis", "opc": "Von Meyenburg complex", "opd": "Caroli's disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "31c159b3-0ca7-4475-9f54-544f2242feef", "choice_type": "single"} {"question": "Largest lymphatic organ in the human body is", "exp": "Spleen: - Largest lymphatic organ connected to blood vascular system. Acts as filter for blood Plays an impoant role in immune response of body Lies mainly in hypochondrium & paly in epigastrium Normally not palpable Supplied by splenic aery - the largest branch of celiac trunk Splenic vein is formed at hilum of spleen Splenic tissue has no lymphatics Sympathetic fibres are derived from celiac plexus Functions: - Phagocytosis Hemopoiesis Immune responses Storage of RBC.", "cop": 2, "opa": "Liver", "opb": "Spleen", "opc": "Thymus", "opd": "Kidney", "subject_name": "Anatomy", "topic_name": "GIT 1", "id": "fa119bc2-ae6a-421f-8333-c4b92791005a", "choice_type": "single"} {"question": "Splenic infarction is associated with", "exp": ".", "cop": 2, "opa": "Typhoid", "opb": "IMN", "opc": "CML", "opd": "Paroxysmal nocturnal hemoglobinuria", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "a21a7057-ed18-470d-986b-4dcaafc042d0", "choice_type": "single"} {"question": "For examination of fungus from a sample, uniformly stain by", "exp": "PAS-periodic acid schiff stain is used for carbohydrate paicularly glycogen, ,amobea, fungi Periodic acid-Schiff (PAS) is a stainingmethod used to detect polysaccharidessuch as glycogen, and mucosubstances such as glycoproteins, glycolipids and mucins in tissues. The reaction of periodic acid oxidizes the vicinal diols in these sugars, usually breaking up the bond between two adjacent carbons not involved in the glycosidic linkage or ring closure in the ring of the monosaccharide units that are pas of the long polysaccharides, and creating a pair of aldehydes at the two free tips of each broken monosaccharide ring. The oxidation condition has to be sufficiently regulated so as to not oxidize the aldehydes fuher. These aldehydes then react with the Schiff reagent to give a purple-magenta color. A suitable basic stain is often used as a counterstain. Refer Robbins page no 8th edition 336", "cop": 2, "opa": "Alzarin", "opb": "PAS", "opc": "Mason trichome", "opd": "Giemsa", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "fe7d207d-acfb-4253-b992-ed00c089d15b", "choice_type": "single"} {"question": "The term infantile polyaeritis nodosa was used for", "exp": "Refer robbins 9/e 506 Kawasaki disease, also referred to as Kawasaki syndrome or mucocutaneous lymph node syndrome, affects children and includes several symptoms: fever rash swelling of the hands and feet irritation and redness of the whites of the eyes swollen lymph glands in the neck irritation and inflammation of the mouth, lips and throat These effects of Kawasaki disease are rarely serious. The acute phase of the condition commonly lasts 10-14 days or more. Most children recover fully. But, in some cases, Kawasaki disease can lead to long-term hea complications.", "cop": 3, "opa": "Goodpasteures syndrome", "opb": "Henoch schalein puurpura", "opc": "Kawasaki diseases", "opd": "Takayasu aerits", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "c40e1136-36d1-4add-ba52-dddf3f653111", "choice_type": "single"} {"question": "Investigation of choice on Meckel's Diveicula in pediatric age group is", "exp": "In case of children 99mTc-peechnetate is preferentially taken up by the mucus secreting cells of gastric mucosa and ectopic gastric tissue in Meckel's Diveicula. In adults less ectopic gastric tissue is seen so the test is not much accurate in adults Ref: Sabiston 20th edition Pgno :1285", "cop": 4, "opa": "USG", "opb": "CT", "opc": "Barium meal", "opd": "Na 99m Tc- peechnetate", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "c3bbbc68-351b-4531-a498-5904f8e72f5c", "choice_type": "single"} {"question": "Transformation of one epithelium to other epithelium is known as", "exp": "Ref: Robbins 8/e p10,11;9/e p37", "cop": 4, "opa": "Dysplasia", "opb": "Hyperplasia", "opc": "Neoplasia", "opd": "Metaplasia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "322ae873-5b9e-4e89-9a0f-c6a636171df6", "choice_type": "single"} {"question": "Closure of neural tube begin from", "exp": "Closure of neural tube at cervical region.\nCronial neuropore closes by 25th day.\nCaudal neuropore closes by 28th day.", "cop": 1, "opa": "Cervical region", "opb": "Cephalic", "opc": "Podalic", "opd": "Lumbar region", "subject_name": "Anatomy", "topic_name": null, "id": "9025fd77-584c-4863-84af-4577f7fcf63d", "choice_type": "single"} {"question": "Most common cause of bilateral Proptosis is", "exp": "Most common cause of either bilateral or unilateral proptosis in adults is thyroid ophthalmopathy Refer khurana 6/e", "cop": 1, "opa": "Thyrotoxicosis", "opb": "Cavernous sinus thrombosis", "opc": "Retinoblastoma", "opd": "Pseudotumers", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7fbc9ecc-2423-41c1-b6fd-5a8f25385267", "choice_type": "single"} {"question": "Infections of the ring finger spread to the", "exp": "Infections of the ring and middle spread into the mid palmar space. Index finger to thenar space Little finger spread to ulnar bursa and mid palmar space. Ref: Internet sources.", "cop": 3, "opa": "Radial bursa", "opb": "Ulnar bursa", "opc": "Mid palmar space", "opd": "Thenar space", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "7c44d063-ede4-4ef2-941d-419e451fe69e", "choice_type": "single"} {"question": "Most common cause of gastric varices is", "exp": "Most common cause of gastric varices : Cirrhosis Most common cause of isolated gastric varices : Splenic vein thrombosis Ref: Sabiston 20th edition Pgno : 1232", "cop": 3, "opa": "Splenic vein thrombosis", "opb": "Splenectomy", "opc": "Cirrhosis", "opd": "Mesenteric thrombosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1c475009-2b02-4043-ade4-e7e8a6b1032d", "choice_type": "single"} {"question": "Average gain in length in first year is", "exp": "Length at bih- 50cms At 3 months- 60cms At 6 months- 65cms At the end of 1st yr- 75cms Hence gain in length in first year is (75-50= 25cms) Ref: Ghai,9th edition, Table 2.1", "cop": 1, "opa": "25cms", "opb": "50cms", "opc": "75cms", "opd": "100cms", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d3cab309-67df-43d1-931e-07423529ac6b", "choice_type": "single"} {"question": "As viewed from the right atrium, the floor of the fossa ovalis is formed by", "exp": "Fossa oavlis represents the site of embryonic spectum primum hence from right atrium its seems to be developed from septum primum. BD CHAURASIA'S HUMAN ANATOMY.VOLUME 1. 6TH EDITION.PAGE NO 255", "cop": 1, "opa": "Septum primum", "opb": "Septum secundum", "opc": "Endocardial cushions", "opd": "Tricuspid valve orifice", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "e2c50ccd-f7b1-4760-8307-d40a0d610905", "choice_type": "single"} {"question": "Most common Paraneoplastic syndrome of HCC", "exp": "Para neoplastic syndromes in HCC Hypocholesterolemia(most common) Hypoglycemia Erythrocytosis Hypercalcemia Ref:Sabiston 20th edition Pgno : 1458-1463", "cop": 1, "opa": "Hypoglycemia", "opb": "Hypeension", "opc": "Hypercalcaemia", "opd": "Erythrocytosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0585563f-db79-458c-a2b8-50540502f2ee", "choice_type": "single"} {"question": "Triangle of Koch is not formed by", "exp": "Triangle of Koch is formed by\n\nTendon of Todaro\nCoronary sinus\nSeptal Cusp of Tricuspid valve", "cop": 1, "opa": "Limbus of Fossa ovalis", "opb": "Tendon of Todaro", "opc": "Coronary sinus", "opd": "Septal Cusp of Tricuspid valve", "subject_name": "Anatomy", "topic_name": null, "id": "eabf77ba-124c-4b55-80ca-5c5cdb84023f", "choice_type": "single"} {"question": "Guanidine special group is presesnt in", "exp": "AMINO ACID SPECIAL GROUP Arginine Guanidinium Proline Pyrolidine Tryptophan Indole Phenylalanine Benzene Tyrosine Phenol Histidine Imidazole Methionine Thioether linkage Reference: Harpers illustrated biochemistry 30th edition", "cop": 1, "opa": "Arginine", "opb": "Proline", "opc": "Tryptophan", "opd": "Tyrosine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ab25dba0-0966-4c4c-8865-35c8826d73be", "choice_type": "single"} {"question": "40 yr old male presented with cirrhosis. Special stain used here is", "exp": ".", "cop": 2, "opa": "Alcian blue", "opb": "Perls Prussian blue", "opc": "Masson Fontana", "opd": "Von kossa", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "eff52569-99ad-43e5-a94a-df78c22fdaf6", "choice_type": "single"} {"question": "Frig causing maximum peripheral neuropathy is", "exp": "Refer WHO recommendations to treat adult and adolescent HIV/76 Stavudine b has maximum incidence of peripheral neuropathy whereas didanosine is associated with maximum risk of acute pancreatitis", "cop": 3, "opa": "Zidovudine", "opb": "Lamivudine", "opc": "Stavudine", "opd": "Didanosine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "aaf453b9-a1b2-4da9-84cf-4024fc90e088", "choice_type": "single"} {"question": "Congenital long QT syndrome can lead to", "exp": "Polymorphic VT has a continually changing QRS morphology indi- cating a changing ventricular activation sequence. Polymorphic VT that occurs in the context of congenital or acquired prolongation of the QT interval often has a waxing and waning QRS amplitude creat- ing a \"twisting about the points\" appearance referred to as Torsade de Pointes Ref Harrison 20th edition pg 1445", "cop": 2, "opa": "Complete hea block", "opb": "Polymorphic ventricular tachycardia", "opc": "Acute myocardial infraction", "opd": "Recurrent supraventricular tachycardia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9a6de744-3c62-47d6-bf7c-1b8c97e83c79", "choice_type": "single"} {"question": "Oil red Or staining is used for", "exp": "ref Bancroft histology 7/e p83 Fresh cryostat sections must be used for oil red o stain", "cop": 1, "opa": "Frozen section", "opb": "Glutaraldehyde fixed specimen", "opc": "Alcohol fixed specimen", "opd": "Formalin fixed specimen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4d8f9a1b-c512-4003-96e2-e23737b303fa", "choice_type": "single"} {"question": "Arrange the following structures in the order they are pierced during lumbar puncture.(SEQUENTIAL ARRANGEMENT) a)Epidural space b)Interspinous ligament c)Supraspinous liament d)Ligamentum flavum e)Subarachnoid space", "exp": "Lumbar puncture in adult: Pt lying on side with maximally flexed spine A line taken between highest points of axis at L4 level Skin cleaned & anesthetised Spinal needle inseed between L4 - L5 veebrae Structures pierced: skin, fat, supraspinous & interspinous ligaments, ligamentum flavum, epidural space, dura, arachnoid, subarachnoid space. CSF", "cop": 4, "opa": "a-b-c-d-e", "opb": "b-c-d-a-e", "opc": "d-c-b-a-e", "opd": "c-b-d-a-e", "subject_name": "Anatomy", "topic_name": "Back region", "id": "d364c004-e60f-40f4-a437-1b37a4c290b1", "choice_type": "single"} {"question": "Nasolacrimal duct opens into", "exp": "Nasolacrimal duct begins at the lower end of the lacrimal sac, runs downwards, backward and laterally, opens into the inferior meatus the nose. Fold of mucous membrane called the valve of Hasner forms an imperfect valve at the lower end of the duct. Ref.BDC volume 3;sixth edition pg no 77", "cop": 2, "opa": "Superior", "opb": "Inferior meatus", "opc": "Middle", "opd": "Sphenoethmoid recess", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "0c88b326-4ae6-4f76-b0db-4bf2714b0a5c", "choice_type": "single"} {"question": "The lymphatic drainage of testes is", "exp": "Blood Supply and Lymphatic Drainage. The testis and epididymis are supplied by the testicular artery, and their veins drain into the pampiniform plexus, which forms the bulk of the spermatic cord. The veins of the pampiniform plexus often become varicose, a condition termed varicocele.", "cop": 3, "opa": "Inguinal lymph node", "opb": "Mesenteric lymph node", "opc": "Para-aortic lymph node", "opd": "Obturator lymph node", "subject_name": "Anatomy", "topic_name": null, "id": "14b2fbf0-59f5-410b-ab53-34cd6e4a2a9b", "choice_type": "single"} {"question": "Cyanosis NOT improving with 100% oxygen in case of", "exp": "Presence of cyanosis that does not improve with supplemental oxygen suggest true pathological cardiac or pulmonary shunting of blood . Ref Harrison 19th edition pg 1248-49", "cop": 4, "opa": "Cardiac asthma", "opb": "Interstitial lung disease", "opc": "Bronchial asthma", "opd": "Tetrology of hea", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "20e6e137-6b7e-4d3a-b0f9-6800733c1f05", "choice_type": "single"} {"question": "The cranial nerve with the largest intra cranial course is", "exp": null, "cop": 2, "opa": "Abducens nerve", "opb": "Trochlear nerve", "opc": "Optic nerve", "opd": "Trigeminal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "e875acfe-a870-49e8-8977-4c798c25d323", "choice_type": "single"} {"question": "Age group affected by Osteosarcoma", "exp": "This is predominantly a tumor of childhood or adolescence, occurring most commonly in the 10-25years Refer Maheshwari 6tg/e p 239", "cop": 2, "opa": "Up-to 10 yrs", "opb": "10 -20 yrs", "opc": "30-40 yrs", "opd": "Older than 45 yrs", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "29a16209-8c16-4620-bd70-68fa9596534f", "choice_type": "single"} {"question": "assosiated with OCD is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "decreased interest in sex", "opb": "normal interest in sex", "opc": "obesity", "opd": "increased interest in sex", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "41717de5-214b-476f-a985-e99240185036", "choice_type": "single"} {"question": "Inhibitors of apoptosis is", "exp": "Ref , Robbins 7/e p29,31,32,9/e p55", "cop": 4, "opa": "P53", "opb": "Ras", "opc": "Myc", "opd": "Bcl-2", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5523dd86-0318-4cc1-96eb-f048e13abc7b", "choice_type": "single"} {"question": "Sec 174CrPC deals with", "exp": "Police inquest The officer in charge of police station conducts the inquest(Sec 174CrPC). The police officer conducting the inquest is called the investigating officer. Police officer may summon persons for investigation purpose according Sec 175Cr PC. Refusak of the summons is punishable upto 6 months and fine upto 1000 rupees. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 7", "cop": 1, "opa": "Policy inquest", "opb": "Magistrate inquest", "opc": "Coroner's inquest", "opd": "Summons", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d514432e-55af-4318-9188-035fae545a50", "choice_type": "single"} {"question": "Visual area of coex is supplied by", "exp": "Occipital lobe or visual coex is supplied by posterior cerebral aery Ref: Gray's40e/p-256", "cop": 3, "opa": "Anterior cerebral aery", "opb": "Middle cerebral aery", "opc": "Posterior cerebral aery", "opd": "Posterior inferior cerebellar aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "10433466-ff72-4555-944d-2a562601a3ba", "choice_type": "single"} {"question": "Adenosine deaminase deficiency is seen in", "exp": "Ref Robbins 8/e p244, 9/e p239 Adenosine deaminase (ADA) deficiency is an inherited disorder that damages the immune system and causes severe combined immunodeficiency (SCID). People with SCID lack viually all immune protection from bacteria, viruses, and fungi. They are prone to repeated and persistent infections that can be very serious or life-threatening. These infections are often caused by \"oppounistic\" organisms that ordinarily do not cause illness in people with a normal immune system", "cop": 1, "opa": "Severe combined immunodeficiency", "opb": "Wiskott Aldrich syndrome", "opc": "Agammaglobulinemia", "opd": "HIV", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5a508c05-49c9-4c8c-8083-96173812b558", "choice_type": "single"} {"question": "Most common cause of liver abscess in chronic granulomatous disease", "exp": "Pyogenic liver abscess in children In children Staphylococcus PLA is most common Occurs in the setting of chronic granulomatous disease disorder of granulocyte function and hematologic malignancies In chronic granulomatous conditions, abscess are dense and thick, early excision and treatment with antibiotics against Staphylococcus aureus is recommended Ref: Sabiston 20th edition Pgno : 1445-1449", "cop": 2, "opa": "Klebsiella", "opb": "Staphylococcus aureus", "opc": "Peptostreptococcus", "opd": "E.coli", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "762d41cf-5bc8-4b2a-892d-81fcdaf135ca", "choice_type": "single"} {"question": "The complication least likely to occur in a pseudocyst of the pancreas", "exp": "Pseudocyst complications Infection (MC) :14% Pain due to expansion Hemorrhage upto 10% Duodenal obstruction Rupture Abscess Ref: Shackelford 7th edition Pgno :1159", "cop": 4, "opa": "Hemorrhage", "opb": "Rupture", "opc": "Infection", "opd": "Carcinomatous change", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "da9670b6-4737-40c6-bc39-ba1393755c18", "choice_type": "single"} {"question": "Mechanism of action of digitalis in atrial fibrillation is", "exp": "(Ref: KDT 6/ep502) Digitalis acts in CHF by inhibiting Na+-K+-ATPase whereas in AF, it acts by decreasing the conduction through AV node.", "cop": 3, "opa": "By Causing bradycarlia", "opb": "Na+ K+ ATPase inhibition", "opc": "Increase in refractoriness of AV nodal tissue", "opd": "By Causing bradycarlia", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "4e6a2874-b8dc-4c3e-966a-ee17c2d24ac2", "choice_type": "single"} {"question": "Nerve supply of the tympanic membrane is by the", "exp": "A i.e. Aurico-temporal nerve", "cop": 1, "opa": "Auriculotemporal", "opb": "Lesser occipital", "opc": "Greater occipital", "opd": "Parasympathetic ganglion", "subject_name": "Anatomy", "topic_name": null, "id": "cedc1ca3-8e0e-447b-9191-8f70137f6174", "choice_type": "single"} {"question": "Epithelial lining of urinary bladder is", "exp": "Urinary bladder is lined with transitional epithelial tissue that is able to stretch significantly to accommodate large volumes of urine. The transitional epithelium also provides protection to the underlying tissues from acidic or alkaline urine. ref - BDC 6e vol2 pg380", "cop": 2, "opa": "Squamous", "opb": "Transitional", "opc": "Cuboidal", "opd": "Columnar", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "574cf54c-00f9-4e02-84a3-c115e2e3d785", "choice_type": "single"} {"question": "Sensory supply of larynx, below the vocal cord", "exp": "Sensory supply: The internal laryngeal nerve supplies the mucous membrane upto the level of the vocal folds. The recurrent laryngeal nerve supplies it below the level of the vocal folds. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Superior laryngeal nerve", "opb": "Inferior laryngeal nerve", "opc": "Recurrent laryngeal nerve", "opd": "Internal laryngeal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "dff03eb5-c290-43da-8588-e3a563a77f01", "choice_type": "single"} {"question": "A posteriorly perforating ulcer in the pyloric antrum of the stomach is most likely to produce initial localized peritonitis or abscess formation in the following", "exp": "\"The posterior surface of the stomach is related to structures forming the stomach bed, all of which are separated from the stomach by the cavity of the lesser sac.\" Thus an ulcer on the posterior wall of the stomach would perforate into the lesser sac. Also, remember Most perforated ulcers are located on the anterior wall. The moality rate for a perforated gastric ulcer is higher than that for duodenal ulcer. This is generally due to the gastric ulcer patients' more advanced age, increased medical comorbidities, delay in seeking medical attention, and the larger size of gastric ulcers. Ref : CSDT 13/e p498", "cop": 1, "opa": "Omental bursa (lesser sac)", "opb": "Greater sac", "opc": "Right subphrenic space", "opd": "Hepato renal space (pouch of Morison)", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b6240682-f7a5-44ec-b37f-822fc896c3c2", "choice_type": "single"} {"question": "Epithelium of ureter develops from", "exp": "Epithelium of ureter developed from Mesonephric duct as the ureteric bud. Ref: Gray's 39e/p-1289", "cop": 1, "opa": "Mesonephros", "opb": "Metanephros", "opc": "Pronephros", "opd": "Paramesonephric duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "69b754b1-1633-47e2-b0a8-10430699d64d", "choice_type": "single"} {"question": "The period of embryo extends", "exp": null, "cop": 4, "opa": "From the first week till the eighth week", "opb": "From the period of ovum till the tenth week", "opc": "From oogenesis till the eight week", "opd": "From fertilization till the eighth week", "subject_name": "Anatomy", "topic_name": null, "id": "be6bac06-afa7-4428-ac15-3d79cb825fa3", "choice_type": "single"} {"question": "Maximum Infant Moality Rate is seen in", "exp": "State (2014)IMR / 1000Tamil Nadu20Orissa/Odisha49Maharashtra22Kerala12Madhya Pradesh52(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no:604)", "cop": 2, "opa": "Tamilnadu", "opb": "Orissa", "opc": "Maharashtra", "opd": "Kerala", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9b4c410a-e506-4e32-bda2-3979c9fd0fef", "choice_type": "single"} {"question": "In the lungs, bronchial arteries supply the bronchopulmonary tree", "exp": "bronchial artery supplies bronchial tree till respiratory bronchiole.", "cop": 3, "opa": "Till tertiary bronchi", "opb": "Till segmental bronchi", "opc": "Till respiratory bronchioles", "opd": "Till alveolar sacs", "subject_name": "Anatomy", "topic_name": null, "id": "5d72b083-2000-41c0-88ea-83a942fac254", "choice_type": "single"} {"question": "AA Direc acting cholinometic that is lipid soluble and has been used in the treatment of glaucoma is", "exp": "Ref-KDT 6/e p98 Pilocarpine is a directly acting and physostigmine is an indirectly acting cholinomimetic useful for glaucoma", "cop": 3, "opa": "Acetylcholine", "opb": "Physostigmine", "opc": "Pilocarpine", "opd": "Neostigmine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "eb9ddc40-2391-4e56-a267-a3b8669f6b3f", "choice_type": "single"} {"question": "Hofbauer cells are tissue macrophages of", "exp": "Hoffbauer cells are the tissue macrophages of placenta", "cop": 2, "opa": "Pancreas", "opb": "Placenta", "opc": "Uterus", "opd": "Liver", "subject_name": "Anatomy", "topic_name": null, "id": "3adbfc20-de3c-4f5c-a466-b4880dd4374b", "choice_type": "single"} {"question": "Most common coronary artery to undergo atherosclerosis is", "exp": "Most common coronary artery to undergo atherosclerosis is Left anterior descending artery", "cop": 3, "opa": "Right Coronary artery", "opb": "Left Circumflex artery", "opc": "Left anterior descending artery", "opd": "Right marginal artery", "subject_name": "Anatomy", "topic_name": null, "id": "444b63d0-5055-4348-b7f2-d3d0ef6c608b", "choice_type": "single"} {"question": "Fetal midgut rotates in IUL", "exp": "During development, midgut undergoes rapid phase of growth in which loops of midgut herniate outside the abdominal cavity of fetus & protrude into umbilical cord This is PHYSIOLOGICAL UMBILICAL HERNIA (occurs at 6 weeks of IUL) At week 10, it comes back to abdominal cavity. When midgut is Herniating into umbilicus, it follows superior mesenteric aery Thus, superior mesenteric aery becomes axis of rotation. While entering umbilical cord there is: 1. High point: duodenojejunal junction (small intestine). 2. Low point: ileocecal junction (large intestine) * Which rotates 1st 90 degree anti- clock wise resulting in small intestine to right side & large intestine to left side. While coming back to abdominal cavity, there would be another 180 degree anti - clock wise rotation. : Total of 270 degree anti-clock wise rotation occurs during development of midgut in IUL Duodenum become C - shaped and have 4 pas and colon will also have 4 pas (Ascending, transverse & descending & sigmoid colon).", "cop": 2, "opa": "270 degree clockwise", "opb": "270 degree anticlockwise", "opc": "360 degree clock wise", "opd": "360 degree anticlockwise", "subject_name": "Anatomy", "topic_name": "Mesentry, neurovascular bundle", "id": "ee4c1243-6cf7-46e4-9938-e5b40a386023", "choice_type": "single"} {"question": "Bradykinin is for", "exp": "Ref Robbins 8/e p65; 7/e p45,9/e p89 Bradykinin is a potent endothelium-dependent vasodilator and mild diuretic, which may cause a lowering of the blood pressure. It also causes contraction of non-vascular smooth muscle in the bronchus and gut, increases vascular permeability and is also involved in the mechanism of pain.", "cop": 1, "opa": "Pain", "opb": "Vasodilation", "opc": "Vasoconstriction", "opd": "Increase in vascular permeability", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "231deec9-4900-4533-a8d8-3d6b29a0ebb9", "choice_type": "single"} {"question": "Sternum attached to scapula (FMGE Dec 2018)", "exp": "By forming sternoclavicular joint & Acromioclavicular joint, clavicle connects sternum (Axial skeleton) to scapula (Appendicular skeleton). Clavicle transmits the weight / force of appendicular skeleton to axial skeleton. acromioclavicular ligament is impoant in this. That's why clavicle is most commonly fractured bone in body -Sternum contains - Manubrium - Body - Xiphoid process * Manubrium of sternum: angled posteriorly on body of sternum at manubriosternal joint, forms sternal angle which is major surface landmark used by clinicians in physical examination. * RIBS: All ribs aiculate with thoracic veebrae posteriorly, most ribs (II to IX) have 3 aiculations with veebral column. anteriorly, costal cailages of ribs I to VII aiculate with sternum, VIII to X aiculate with inferior margins of costal cailage above them, XI & XII floating ribs - because they do not aiculate with ribs, costal cailage or sternum", "cop": 2, "opa": "Manubrium", "opb": "Clavicle", "opc": "First rib", "opd": "Second rib", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "26918341-7369-44e2-8034-8bd96272bc2a", "choice_type": "single"} {"question": "Pulsations of the following aery can be felt over the zygoma", "exp": "The superficial temporal aery enters scalp in front of root of zygoma and divides into anterior and posterior branches.The pulsations of the facial aery can be felt 1.25 cm lateral to the angle of the mouth.Reference: Textbook of anatomy, head neck, and brain, Vishram Singh, 2nd edition, page no.49", "cop": 4, "opa": "Transverse facial aery", "opb": "Facial aery", "opc": "Deep temporal aery", "opd": "Superficial temporal aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b1ead724-3864-4e64-a996-9b3a4a0c6e70", "choice_type": "single"} {"question": "Alpha 1 anti trypsin deficiency is seen in", "exp": "Alpha 1 anti trypsin deficiency is associated with panacinar emphysema Emphysema is a type of COPD involving damage to the air sacs (alveoli) in the lungs. As a result, your body does not get the oxygen it needs. Emphysema makes it hard to catch your breath. You may also have a chronic cough and have trouble breathing during exercise. The most common cause is cigarette smoking. Refer robbins 9/e p466", "cop": 1, "opa": "A. Emphysema", "opb": "B. Bronchiectasis", "opc": "C. Empyema", "opd": "D. Bronchiogenic carcinoma", "subject_name": "Anatomy", "topic_name": "Breast", "id": "8e706ce5-678c-4335-94eb-947425d78c0a", "choice_type": "single"} {"question": "Association fibres are A/E", "exp": "D i.e. Forceps major", "cop": 4, "opa": "Uncinate", "opb": "Cingulum", "opc": "Longitudinal fasciculus", "opd": "Forceps major", "subject_name": "Anatomy", "topic_name": null, "id": "f442aeac-645e-4d7c-9955-132af0a57cb6", "choice_type": "single"} {"question": "Lateral boundry of ischiorectal fossa is formed by", "exp": "Boudaries of ischiorectal fossa\nAnterior - Perineal membrane\nPosterior - Gluteus maximus\nLateral - Obturator internus\nMedial - External anal sphincter and levator ani", "cop": 4, "opa": "Gluteus maximus", "opb": "Levator ani", "opc": "Gluteus minimus", "opd": "Obturator internus", "subject_name": "Anatomy", "topic_name": null, "id": "5b68f8f2-e8a6-48a0-8a8f-9d35fa92d057", "choice_type": "single"} {"question": "Deep nucleus of cerebellum", "exp": "Nucleus of cerebellum (Lateral to medial ):Dentate, emboliform, globose &fastigial Cerebellar nuclei function Dentate working with lateral pa Co-ordinate movement of joint Fastigial working with central vermis Saccadic eye movement. Interposed nuclei (emboliform & globose) working with para vermal area Feedback mechanism from joints to have proper co- ordination of joint. Caudate nucleus and Lentiform nucleus (inner Globus pallidus + outer putamen) are Basal ganglia nuclei.", "cop": 4, "opa": "Lentiform", "opb": "Caudate", "opc": "Putamen", "opd": "Fastigial", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "2c03b838-354b-4757-88fd-8c24c61d7e70", "choice_type": "single"} {"question": "ANCA antibody with peripheral rim distribution is indicative of", "exp": "Ref 9/e p219,8/e p214,7/e 228 Antinuclear antibodies. ANAs are directed against several nuclear antigens and can be grouped into four catego- ries: (1) antibodies to DNA, (2) antibodies to histones, (3) antibodies to nonhistone proteins bound to RNA, and (4) antibodies to nucleolar antigens. Table 4-10 lists several autoantibodies, including ANAs, and their asso- ciation with SLE as well as with other autoimmune dis- eases, to be discussed later. The most widely used method of detecting ANAs is the indirect immunofluo- rescence assay (IFA), which screens for autoantibodies that bind to a variety of nuclear antigens, including DNA, RNA, and proteins. Four staining patterns are seen with IFA: homogeneous or diffuse, rim or periph- eral, speckled, and nucleolar. While each pattern can be suggestive of the presence of specific autoantibodies, the strength of these associations is limited and should not be relied on. ANA testing by IFA is extremely sensitive, as more than 95% of patients with SLE will test positive, but the test's specificity is quite limited, because patients with other autoimmune diseases, chronic infections, and cancer will test positive as well. Fuhermore, ANAs are seen in approximately 5% to 15% of healthy people, and the incidence increases with age. Recently, the IFA has been replaced in many clinical laboratories by multiplex flow cytometry immunoassays that can simultaneously test for multiple specific autoantibodies, but these assays may lack the sensitivity of the IFA. Antibodies to double- stranded DNA (dsDNA) and the so-called Smith (Sm) antigen can be detected by ELISA or multiplex flow methods and are specific for SLE. * Other autoantibodies. Antibodies against blood cells, including red cells, platelets, and lymphocytes, are found in many patients. Antiphospholipid antibodies are present in 40% to 50% of patients with lupus and react with a wide variety of proteins in complex with phospholipids. Some bind to cardiolipin antigen, used in serologic tests for syphilis, so patients with lupus may have a false-positive test result for syphilis. Antiphos- pholipid antibodies contribute to coagulation abnormal- ities,", "cop": 3, "opa": "Antihistone antibody", "opb": "Anti Smith antibody", "opc": "Anti double stranded DNA antibody", "opd": "Anti double stranded RNA antibody", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "76b213fb-f7a6-48a4-807b-0ad4b8bf52d2", "choice_type": "single"} {"question": "According to strasberg classification, lateral CBD injuries are classified as", "exp": "Strasberg classification of Laparoscopic Biliary injuries Type A- Bile leaks from minor ducts still in continuity with the CBD IIncludes leakage from cystic duct stump and from a subvesical duct of Luschka. MC cause of biliary leaks seen after cholecystectomy. Type B- Occlusion of a pa of the biliary tree, almost always an aberrant right sectoral duct Type C- Transection without ligation of an aberrant right sectoral duct. Type D- A lateral injury to an extrahepatic duct. Type E- Includes biliary strictures, divided into E1 to E5 as classified by Bismuth Ref: Sabiston 20th edition Pgno :1502", "cop": 3, "opa": "Type B", "opb": "Type C", "opc": "Type D", "opd": "Type E", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8cb1c38b-6240-4df6-822d-0700fceb7f68", "choice_type": "single"} {"question": "The immunosuppressant action of cyclosporin appears to be due to", "exp": "Ref-KDT 6/e p838,839,840 Cyclosporine and tacrolimus acts by inhibiting calcineurin, which is involved in the activation of NFAT. Final result of this process is increased transcription of IL-2 gene. Sirolimus does not inhibit the transcription of IL-2 but interferes with its action. It inhibits the enzyme tyrosine kinase, known as mTOR (which is activated by IL-2).", "cop": 3, "opa": "Activation of NK cells", "opb": "Blockade of tissue response to inflammatory mediators", "opc": "Inhibition of Gene transcription of interleukin", "opd": "Interference with antigen recognition", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "87936748-5bb8-4319-9f63-c083e15d9116", "choice_type": "single"} {"question": "If circumflex aery gives the posterior interventricular branch, this circulation is described as", "exp": "In about 10% of heas,the right coronary is rather small and is not able to give the posterior interventricular branch. In these cases the circumflex aery,the continuation of left provides the posterior interventricular branch and called left dominant. B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME1 SIXTH EDITION Page no:265", "cop": 2, "opa": "Right dominance", "opb": "Left dominance", "opc": "Codominance", "opd": "Undetermined", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "9988d555-e41d-4f02-b78f-60f6b6f93b66", "choice_type": "single"} {"question": "In left oblique breech presentation head engages in", "exp": "Head in breech engages in opposite oblique diameter as that occupied by buttocks.since breech is in left oblique hence head will engage in right oblique diameter", "cop": 1, "opa": "Right oblique", "opb": "Left oblique", "opc": "Right transverse", "opd": "Left transverse", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "f8591b05-d68f-4e4c-8480-c6ea4c4ae632", "choice_type": "single"} {"question": "Persistence of omphalomesenteric duct is (JIPMER May 2019)", "exp": "- Omphalomesenteric duct present inside the umbilical cord of baby is also called as vitello-intestinal duct * Yolk sac - forms gut tube (foregut, midgut & hindgut) * Midgut would be communicating with yolk sac by a duct called vitello-intestinal duct * This duct would be obliterated in course of time; if not results in Meckel's anomaly. (diveiculum/ fistula/ sinus/ cyst etc) present at anti-mesenteric border * Baby will be born with fecal matter at the umbilicus. * Meckel's anomaly - True anomaly as it has all the layers of the gut tube. - presented with pain at umbilicus (referred pain of midgut) Omphalomesenteric duct anomalies Meckel's diveiculum 98% of omphalomesenteric duct anomalies Meckel's diveiculum connected to the umbilicus by a fibrous cord Umbilical cyst. A fibrous cord connecting the ileum to the umbilicus predisposes to volvulus and bowel obstruction Umbilicoieleal fistula: Patent omphalomesenteric duct, resulting in fecal drainage from the umbilicus.", "cop": 3, "opa": "Gastroschisis", "opb": "Omphalocele", "opc": "Meckel's diveiculum", "opd": "Ectopia vesicae", "subject_name": "Anatomy", "topic_name": "JIPMER 2019", "id": "7ab18252-8bbc-4c83-b6b4-1425f765f5f1", "choice_type": "single"} {"question": "Gerlach tonsil in Waldayer&;s ring is", "exp": "A collection of lymphoid tissue is present in the nasopharynx, behind the tubal opening. It is called the tubal tonsil, also known as Gerlach's tonsil. It is continuous with the lateral pa of the pharyngeal tonsil. In Waldeyer's lymphatic ring, the most impoant aggregations are the right and left palatine tonsils. Posteriorly and above there is the pharyngeal tonsil; laterally and above there are the tubal tonsils, and inferiorly there is the lingual tonsil over the posterior pa of the dorsum of the tongue. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 1, "opa": "Tubal tonsil", "opb": "Palatine tonsil", "opc": "Pharyngeal tonsil", "opd": "Lingual tonsil", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "3a561db9-29af-4a06-821b-d9ff7fd37e86", "choice_type": "single"} {"question": "Agent of Chancroid is", "exp": "Chancroid is an STD that presents as a genital ulcer. It is caused by H.ducreyi", "cop": 3, "opa": "H.influenzae", "opb": "H.aegyptius", "opc": "H.ducreyi", "opd": "H.haemolyticus", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "3d5369e1-e63d-4f10-be2e-97e64a4dc9a9", "choice_type": "single"} {"question": "Treatment of choice in SSPE is", "exp": ".", "cop": 4, "opa": "Abacavir", "opb": "Glatiramer", "opc": "Interferon", "opd": "Inosine pranobex", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "fea91175-78b1-460a-9965-8bf680705980", "choice_type": "single"} {"question": "Psammoma bodies are seen in", "exp": "Refer Robbins page no Papillary carcinoma arr recognised based on nulcear6 features even in the absence of papillae. Psmmamoma bodies are a characteristic feature of papillary cancers these neoplasm often metastasizw6 by way of lymphatics, but the prognosis is excellent", "cop": 1, "opa": "Papillary carcinoma of thyroid", "opb": "Medullary carcinoma of thyroid", "opc": "Follicular carcinoma of thyroid", "opd": "Anaplastic carcinoma", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "110cfc4f-b964-41db-b7c8-12d38a719756", "choice_type": "single"} {"question": "Physiological unlocking is caused by", "exp": "Locking is produced by continued action of the same muscles that produce extension, i.e. the quadriceps femoris (the vastus lateralis, vastus medialis , vastus intermedius and the rectus femoris ). The locked knee joint can be flexed only after it is unlocked i.e., by lateral rotation of the femur. Unlocking is brought about by the action of the popliteus muscle. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2, pg. no. 157", "cop": 1, "opa": "Popliteus", "opb": "Rectus femoris", "opc": "Semi-membranous", "opd": "Saorius", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "df717f16-3caa-48ca-b393-9856e65c35f0", "choice_type": "single"} {"question": "Damage to the internal laryngeal nerve results in", "exp": "Anesthesia of larynx", "cop": 3, "opa": "Hoarseness", "opb": "Loss of timbre of voice", "opc": "Anaesthesia of the larynx", "opd": "Brathing difficulty", "subject_name": "Anatomy", "topic_name": null, "id": "32bfcabe-3e53-40fd-8e16-bf62a484c47f", "choice_type": "single"} {"question": "A Lymph node biopsy is taken in the posterior triangle of the neck. The most likely nerve damage occure", "exp": "i.e. (Accessory): (843- Snell 8th) (132-133- BDC-8 5th ed)When a superficial incision is made in the posterior triangle, the nerve most likely to be injured is spinal accessory nerve, because it runs through a tunnel in the fascia forming the roof of the triangle.In the posterior triangle of the neck, the spinal part of the accessory nerve is relatively superficial as it emerges from the posterior border of the stemocleido mastoid and runs down ward and back ward to pass beneath the anterior border of the trapezius.POSTERIOR TRIANGLEThe posterior triangle is bounded posteriorly by the trapezius muscle, anteriorly by the sternocleidomastoid muscle and inferiorly by the clavicle. The posterior triangle of the neck is further subdivided by the inferior belly of the omohyoid muscle into a large occipital triangle above and a small supraclavicular triangle below.Nerves in the posterior triangle of neck (only motor nerve)* Spinal accessory nerve* Two small branches to levator scapulae* Nerve to Rhomboide* Nerve to serratus anterior* Nerve to subclavius* Suprascapular nerve", "cop": 2, "opa": "Phrenic", "opb": "Accessory", "opc": "Upper brachial plexus", "opd": "Lower brachial plexus", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "15869a1a-8799-4e1d-9d38-3fb08ca5649e", "choice_type": "single"} {"question": "BIRADS stands for", "exp": "Category 1 Incomplete assessment, need additional imaging evaluation Category 2 Negative, routine mammogram in 1yr is recommended Category 3 Benign findings, routine management in 1 year is recommended Category 3 Probably benign findings, sho term follow up suggested Category 4 Suspicious abnormality, biopsy should be considered Category 5 Highly suggestive of malignancy, appropriate action should be taken Category 6 Known biopsy - proven malignancy", "cop": 1, "opa": "Breast Imaging Repoing and Data System", "opb": "Best Imaging Repoing and Data System", "opc": "Brain Imaging Repoing and Data System", "opd": "Blood Imaging Repoing and Data System", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "30c4e8e4-3a2e-459c-b360-30a139a26e64", "choice_type": "single"} {"question": "Cervical veebra is differentiated from the thoracic veerbra by the presence of", "exp": "Ans. d. Foramen transversarium", "cop": 4, "opa": "Large veebral body", "opb": "Upwards facing facets", "opc": "Triangular for amina", "opd": "Foramen transversarium", "subject_name": "Anatomy", "topic_name": null, "id": "4469a039-277e-49a8-8323-2461a5c11040", "choice_type": "single"} {"question": "Aqueous humor is produced by the", "exp": "Aqueous humor is produced by the ciliary processes of the ciliary body. It flows from the posterior chamber, through the pupil, into the anterior chamber, and finally to the canal of Schlemm, which empties into the extraocular/episcleral veins.", "cop": 3, "opa": "Choroid plexus", "opb": "Trabecular meshwork", "opc": "Ciliary processes", "opd": "Vitreous body", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "1b0fc7b8-2756-4886-92f6-fcaf3fb4dc7b", "choice_type": "single"} {"question": "The fascia around the nerve bundle of brachial plexus is derived from", "exp": "The fascia around the brachial plexus is called axillary sheath and is a derivative of preveebral fascia Axillary sheath covers brachial plexus and axillary vessels Axillary sheath localises the anesthetic solution to the nerve plexus. Ref : Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 777", "cop": 1, "opa": "Preveebral fascia", "opb": "Deep cervical fascia", "opc": "Clavipectoral fascia", "opd": "Pectoral fascia", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "17706db7-0e9b-4348-ae1f-9e281e351071", "choice_type": "single"} {"question": "Most common lymphoma associated with Sicca syndrome is", "exp": ".", "cop": 2, "opa": "DLBCL", "opb": "MALToma", "opc": "Burkitt lymphoma", "opd": "Lymphoplasmacytic lymphoma", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1c1f3901-c873-423b-a627-11d21c7fb801", "choice_type": "single"} {"question": "Deep peroneal nerve supplies", "exp": "DEEP PERONEAL:- Muscular branches to muscles of anterior compament of leg: Tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus teius.Extensor digitorum brevis Cutaneous: dorsal digital nerves for adjacent sides of big toe and second toe. Aicular branches: Ankle joint, tarsal joints, tarsometatarsal joints and metatarsophalangeal joint of big toe. {Reference:BDC 6E }", "cop": 1, "opa": "1st web space of foot", "opb": "5th web space of foot", "opc": "Antero lateral dorsum of foot", "opd": "Lateral pa of leg", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "a700599b-5c96-4969-a469-06cffd71157f", "choice_type": "single"} {"question": "Superior parathyroid glands are derived from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:136 Depament of parathyroid glands Parathyroid glands are derived as follows: The inferior parathyroid glands develop from endoderm of the third pharyngeal pouch The superior parathyroid glands develop from the endoderm of the fouh pharyngeal pouch", "cop": 3, "opa": "1st branchial pouch", "opb": "3rd branchial pouch", "opc": "4th branchial pouch", "opd": "5th branchial pouch", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2b15a3e1-1555-4c1b-8564-24bd768c2052", "choice_type": "single"} {"question": "F00 in ICD denotes", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref. Internation classification of diseases, 10 th edition", "cop": 1, "opa": "organic disorders", "opb": "psychosis", "opc": "subsatnce use", "opd": "mood disorders", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "30490669-5def-47e6-993c-725043e7b19a", "choice_type": "single"} {"question": "Movement of shoulder joint is controlled by", "exp": "Nerue Supply to shoulder joint Axillary nerve.(C5,C6) Musculocutaneous nerve.(C5,C6,C7) Suprascapular nerve. Ref - BDC 6the p 144", "cop": 2, "opa": "C8 T1", "opb": "C5 6 7 8", "opc": "C4 5 6", "opd": "C7 8 T1 2", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f09adb34-9fb2-48d9-851c-30fbdb2c24c9", "choice_type": "single"} {"question": "Alkalinization of urine is required for decreasing poisoning due to", "exp": "For acidic drug poisoning like (barbiturates, salicylates and methotrexates) ,urinary alkinization agents are prescribed where as basic drug poisoning (morphine, amphetamine ,atropine etc) urinary acidification agents are prescribed. Refer Ltd 7/e p29", "cop": 1, "opa": "Barbiturates", "opb": "Amphitamines", "opc": "Alcohol", "opd": "Morphine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a1d60a6a-0e17-46d7-8f00-8a3ec21e6c8b", "choice_type": "single"} {"question": "The suture between the two halves of the Frontal\nbones is", "exp": "Frontal bone ossifies in membrane. \nIt develops from 2 centres near frontal eminences, during 8th week of intrauterine life.\nAt birth, the bone is in 2 halves, separated in the midline by a suture, known as metopic suture, which soon starts to fuse.\nThe metopic suture occasionally persists in 3 to 8% of individuals.", "cop": 1, "opa": "Metopic", "opb": "Symphysis", "opc": "Mendosal", "opd": "Coronal", "subject_name": "Anatomy", "topic_name": null, "id": "53b00c4e-2ed9-4442-93bf-dbb581398335", "choice_type": "single"} {"question": "The upper 1/3rd of vagina develops from", "exp": "Upper 1/3rd of vagina develops from uterovaginal canal(mesoderm) which is the union of lower veical pa of paramesonephric or mullerian duct. Lower 2/3rd of vagina develops from paramesonephric or mullerian tubercle arises from endoderrm of definitive urogenital sinus which gives two solid evagenations. The 2 solid evagenations growup and form sinovaginal bulb and then the 2 sinovaginal bulbs fuse together forming a thick cellular plate called the vaginal plate .", "cop": 1, "opa": "Mullerian ducts", "opb": "Wolffian ducts", "opc": "Sinovaginal bulbs", "opd": "Endoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "66662830-2545-43a9-b173-73c01de08454", "choice_type": "single"} {"question": "In presence of secondary sexual characters cause screening for primary amenorrhea is done at", "exp": "Primary amenorrhoea is defined as the absence of secondary sexual characters by 14 yrs of age or absence of menarche in the presence of secondary sexual characters till 16 yrs of age, In the sequence of pubeal development the changes are as follows thelarche, increased growth spu, pubarche, menarche. As menarche is the last stage ,in case secondary sexual characters have developed to account for constitutional delay investigation is begun at 16 years.", "cop": 3, "opa": "12years", "opb": "14 years", "opc": "16 years", "opd": "18 years", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "698220f5-3f8d-4d96-8b29-55c18b9dff28", "choice_type": "single"} {"question": "Coronary sinus is guarded by", "exp": "Opening of coronary sinus is guarded by thebesian valve. BD CHAURASIA'S HUMAN ANATOMY VOLUME 1. 6TH EDITION.Page no -255", "cop": 2, "opa": "Crista terminalis", "opb": "Thebesian valve", "opc": "Mitral valve", "opd": "Spiral valve", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "61fff68c-f4e6-4d44-80ed-13aa0da0b23b", "choice_type": "single"} {"question": "Metabolism of a drug primarily results in", "exp": "Ref-Katzung 10/e p50 After metabolism most of the drugs become inactive and their excreted through the kidney. Lipids soluble drugs wil be reabsprbed whereas water soluble drugs are easily excreted.thus, metabolism of drugs helps in the conversion of liquid soluble drugs to water soluble metabolites", "cop": 3, "opa": "Activation of the active drug", "opb": "Conversion of prodruv to active metabolite", "opc": "Conversion of lipid soluble drugs to water soluble metabolites", "opd": "Conversion of water soluble drugs to lipid solible metabolites", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "2fcd6367-0133-468f-b0ab-b7e2d1b74920", "choice_type": "single"} {"question": "Upper border of thyroid cailage is at", "exp": "The thyroid gland lies against veebrae C5, C6, C7 and T1 embracing the upper pa of the trachea Each lobe extends from the middle of cailage to the fouh or fifth tracheal ring The isthmus extends from second to the fouh tracheal ring Ref BDC volume3,6th edition pg 140", "cop": 2, "opa": "C2", "opb": "C5", "opc": "C6", "opd": "T1", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "08c8c33d-d440-4560-98db-12db133c123e", "choice_type": "single"} {"question": "The lymphatic drainage to central pa of the lip is", "exp": "Submental lymph nodes: these are three or four nodes situated across the midline below the chin in the submental triangle. Lymphatics of the central pa of the lower lip drain to the submental nodes,the lymphatics from the rest of the lower lip pass to the submandibular nodes. REF.BDC VOL.3,FIFTH EDITION", "cop": 2, "opa": "Submandibular node", "opb": "Submental nodes", "opc": "Deep cervical nodes", "opd": "Jugulodiagastric nodes", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9200ba92-5bf3-4fd4-a274-92c8f5786de8", "choice_type": "single"} {"question": "The immunoglobulin involved in type 1 hypersensitivity reactions is", "exp": "Ref Robbins 9/e p202 Immediate hypersensitivity is a tissue reaction that occurs rapidly (typically within minutes) after the interaction of antigen with IgE antibody that is bound to the surface of mast cells in a sensitized host. The reaction is initiated by entry of an antigen, which is called an allergen because it triggers allergy. Many allergens are environmental substances that are harmless for most persons on exposure. Some people apparently inherit genes that make them susceptible to allergies. This susceptibility is manifested by the propen- sity of such persons to mount strong TH2 responses and, subsequently, to produce IgE antibody against the aller- gens. The IgE is central to the activation of the mast cells and release of mediators that are responsible for the clinical and pathologic manifestations of the reaction. Immediate hypersensitivity may occur as a local reaction that is merely annoying (e.g., seasonal rhinitis, or hay fever), severely debilitating (asthma), or even fatal (anaphylaxis).", "cop": 1, "opa": "IgE", "opb": "IgM", "opc": "IgA", "opd": "IgG", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b139c8e5-a066-47dc-a151-d93e41ab0197", "choice_type": "single"} {"question": "In klumpke's paralysis nerve roots involved are", "exp": "In klumpke's paralysis lower trunk of brachial plexus is involved that is mainly T1 and paly C8. C6 is mainly involved in Erb's paralysis along with C5. B D Chaurasia 7th edition Page no: 59", "cop": 3, "opa": "C6 -C7", "opb": "C7- C8", "opc": "C8-T1", "opd": "T1-T2", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a4e9845e-cb27-47c7-b616-6ddc1eb1fc8d", "choice_type": "single"} {"question": "Physiological locking is", "exp": "A i.e., Internal rotation of femur over stabilized tibia", "cop": 1, "opa": "Internal rotation of femur over stabilized tibia", "opb": "Internal rotation of tibia over stabilized femur", "opc": "External rotation of tibia over stabilized tibia", "opd": "External rotation of femur over stabilized tibia", "subject_name": "Anatomy", "topic_name": null, "id": "8556fc0b-af23-4daf-9c80-9d2a4e694c6a", "choice_type": "single"} {"question": "Triangle of doom is bounded by A/E", "exp": "C i.e. Cooper's ligament", "cop": 3, "opa": "Vas deferens", "opb": "Gonadal vessels", "opc": "Cooper's ligament", "opd": "Peritoneal fold", "subject_name": "Anatomy", "topic_name": null, "id": "e679066f-bd76-4965-9fab-4585589c7372", "choice_type": "single"} {"question": "Hea failure cells are seen in", "exp": "Ref Robbins 8/e p535, 7/e p122,9/e p116 Cut surfaces of hyperemic or congested tissues feel wet and typically ooze blood. On microscopic examination, acute pulmonary congestion is marked by blood-engorged alveolar capillaries and variable degrees of alveolar septal edema and intra-alveolar hemorrhage. In chronic pulmo- nary congestion, the septa become thickened and fibrotic, and the alveolar spaces contain numerous macrophages laden with hemosiderin (\"hea failure cells\") derived from phagocytosed red cells", "cop": 2, "opa": "Chronic venous congestion of liver", "opb": "Chronic venous congestion of lung", "opc": "Acute venous congestion of lung", "opd": "Acute venous congestion of liver", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "74307fd5-f636-429e-a284-ba3531ba248a", "choice_type": "single"} {"question": "Following resection of 2/3rd of the liver, regeneration is complete within", "exp": "Following resection of 2/3rd of liver, regeneration is complete within 5-6 months", "cop": 3, "opa": "2-3 months", "opb": "8-10weeks", "opc": "4-6 months", "opd": "4-5 weeks", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0b214d33-6177-40b8-9044-59c2ccdbd0ea", "choice_type": "single"} {"question": "Best suture for common bile duct is", "exp": "Synthetic absorbable suture such as vicryl is preferred for CBD Vicryl sutures are used in general soft tissue approximation and vessel ligation Non absorbable sutures ordinarily remain when they are buried within the tissues. This can cause late complications such as the development of gallstones around Non-Absorbable sutures in the CBD or bladder stones in the urinary bladder. In these situations it is best to use absorbable materials Ref: Shackelford 7th edition Pgno : 2222-2224", "cop": 1, "opa": "Synthetic absorbable", "opb": "Synthetic Non-Absorbable", "opc": "Non-synthetic absorbable", "opd": "Non-synthetic Non-Absorbable", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6d839bc8-4195-4f71-acd4-6130b0d67211", "choice_type": "single"} {"question": "Burr cell is seen in", "exp": "Ref Tejinder Singh 1/e p38, robbins 9/e pg 418 Other causes of microangiopathic hemolytic anemia include malignant hypeension, systemic lupus erythematosus, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and disseminated cancer. The morphologic alterations in the injured red cells (schistocytes) are striking and quite characteristic; \"burr cells,\" \"helmet cells,\" and \"triangle cells\" may be seen Burr Cell Uremia at 40x Magnification.Uremia is a condition in which urea and other nitrogenous substances accumulate to an abnormally high level in the blood. ... Some cases of uremia have also been associated with abnormal red blood cells, such asechinocytes, which are often better known asburr cells.", "cop": 1, "opa": "Uremia", "opb": "Hepatocellular carcinoma", "opc": "Gastric carcinoma", "opd": "Ovarian cancer", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "894473e3-cbdf-490e-a342-cffca235895d", "choice_type": "single"} {"question": "Capillary refill time in a child with shock is", "exp": "Capillary refill is a simple test that assesses how quickly blood returns to the skin after pressure is applied. It is carried out by applying pressure to the pink pa of the nail bed of the thumb or big toe in a child and over the sternum or forehead in a young infant for 3 seconds. The capillary refill time is the time from release of pressure to complete return of the pink color. It should be less than 3 seconds. If it is more than 3 seconds the child may be in shock. Lift the limb slightly above hea level to assess aeriolar capillary refill and not venous stasis. This sign is reliable except when the room temperature is low, as the cold environment can cause a delayed capillary refill. In such a situation check the pulses and decide about shock", "cop": 3, "opa": "> 1 second", "opb": "> 2 seconds", "opc": "> 3 seconds", "opd": "> 4 seconds", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d553e300-55e7-4220-bd67-cb63f02d16b9", "choice_type": "single"} {"question": "Cell matrix adhesion are mediated by", "exp": "ref, Robbins 8/e p96;9/ep24 The cell adhesion molecules are classified into four main families: Immunoglbulin family CAMs Cadherins Selectins", "cop": 2, "opa": "Cadherins", "opb": "Integrins", "opc": "Selectins", "opd": "Calmodulin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "64904449-12d5-46c5-8a8a-1e67d65021a4", "choice_type": "single"} {"question": "The initial investigation of choice for a post cholecystectomy biliary stricture is", "exp": "Computed Tomography CT is probably the best initial study, the results which help direct fuher investigations A good quality CT scan shows a dilated biliary tree and helps localise the level of ductal obstruction in patients with strictures CT identities fluid collections or ascites, which may suggest the possibility of vascular damage Other Radiological investigations in post cholecystectomy bile duct injury Duplex ultrasonography Percutaneous transhepatic cholangiography Magnetic resonance cholangiopancreatography. ERCP Isotopic scanning techniques Aretriography and delayed phase poography Ref: Blumga 5th edition Pgno :627", "cop": 3, "opa": "Ultrasound guided aspiration", "opb": "ERCP and stenting", "opc": "Computed tomography", "opd": "Magnetic resonance imaging", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "943dbd78-f150-437e-9afe-7ceb743a78b6", "choice_type": "single"} {"question": "Most common cause of biliary stricture is", "exp": "Most common cause of benign biliary stricture is laparoscopic cholecytectomy I.e., operative trauma Incidence of bile duct injury during laparoscopic cholecystectomy is 0.3-0.85 % Ref:Sabiston 20th edition Pgno :1502", "cop": 2, "opa": "CBD stone", "opb": "Trauma", "opc": "Asiatic cholangitis", "opd": "Congenital", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "c98bafb3-813c-41e7-ad8e-bae4ac37221d", "choice_type": "single"} {"question": "Remnants of Wolffian ducts in a female are found in", "exp": "Ganer's ductwhich is a remnant of wolffian duct, is present inbroad ligament.", "cop": 3, "opa": "Pouch of Douglas", "opb": "Uterovesical pouch", "opc": "Broad ligament", "opd": "lliac fossa", "subject_name": "Anatomy", "topic_name": "NEET Jan 2020", "id": "e9177048-1c1c-4755-b932-ea1a86068805", "choice_type": "single"} {"question": "Order of structures in Porta hepatis are", "exp": "Arrangement of structures at Porta hepatis from anterior to posterior\n = Bile duct \n = Hepatic artery\n = Portal vein", "cop": 2, "opa": "= Right anterior - Portal vein ; = Posterior hepatic artery ; = Left anterior - Bile duct", "opb": "= Right anterior - Bile duct ; = Posterior - Hepatic artery ; = Left anterior - Portal vein", "opc": "= Right anterior - Portal vein ; = Posterior - Bile duct ; = Left anterior - hepatic artery", "opd": "= Right anterior - Hepatic artery ; = Posterior -Posterior Vein ; = left anterior - Bile duct", "subject_name": "Anatomy", "topic_name": null, "id": "ec6c159a-1316-4286-bf66-abb5ff4db4ba", "choice_type": "single"} {"question": "Strasberg'e class 'B' bile injury means", "exp": "Strasberg classification of Laparoscopic Biliary injuries Type A- Bile leaks from minor ducts still in continuity with the CBD Includes leakage from cystic duct stump and from a subvesical duct of Luschka. MC cause of biliary leaks seen after cholecystectomy. Type B- Occlusion of a pa of the biliary tree, almost always an aberrant right sectoral duct Type C- Transection without ligation of an aberrant right sectoral duct. Type D- A lateral injury to an extrahepatic duct. Type E- Includes biliary strictures, divided into E1 to E5 as classified by Bismuth Ref: Sabiston 20th edition Pgno :1502", "cop": 2, "opa": "Bile leak from a minor duct", "opb": "Occlusion of a branch of biliary tree", "opc": "Injury of bile duct not in communication with CBD", "opd": "Circumferential injury to major bile ducts", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "54c9f07f-61d3-41d5-8e40-5be92df848af", "choice_type": "single"} {"question": "Cochleate uterus is", "exp": "Cochleate uterus: A small adult uterus with a conical cervix and a body that is small, globular, and acutely flexed. ref - pubmed.com", "cop": 2, "opa": "Large uterus", "opb": "Acute anteflexion", "opc": "Acute retroflexion", "opd": "Large cervix", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "cf56589e-dfb1-478a-a10d-ce3cf3ab7c9e", "choice_type": "single"} {"question": "Transverse ulcers are seen in", "exp": "Robbins page no Pg p376 This very rare affection of unknown origin, achieves a macroscopic and microscopic aspect similar to that described by Cruveillhier at the level of the stomach. The authors present a case of ulcer located on the transverse colon, at the free margin, with stenosing evolution and coexisting with duodenal ulceration of chronic character. The patient also had poal hypeension in the third stage and aeriopathy that had been diagnosed previously. Macroscopically, TB classically causesulceration, sho strictures, marked thickening of the bowel wall due to inflammation, fibrosis and adhesions, or a combination of these. The ulcers are transverse, often circumferential, with ill-defined, sloping or overhanging edges", "cop": 2, "opa": "Typhoid", "opb": "Tuberculosis", "opc": "Amoebiaisis", "opd": "Ulcerative colitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "05648b9c-50de-4984-9103-85d5c225a17b", "choice_type": "single"} {"question": "Best diagnostic method for breast lump is", "exp": "First investigation for tissue sampling : FNAC Best and diagnostic investigation : Biopsy Ref: Sabiston 20th edition Pgno: 826-828", "cop": 3, "opa": "USG", "opb": "Mammogram", "opc": "Biopsy", "opd": "FNAC", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "d0257875-68d6-47e5-a19a-58f97581806a", "choice_type": "single"} {"question": "Immunostimulant used for the treatment of malignant Melanoma Norma is", "exp": "Ref-Katzung 10/e p906 It is a recombinant IL-2 used for the treatment of renal cell carcinoma and malignant melanoma", "cop": 3, "opa": "Levamisol", "opb": "BCG", "opc": "Aldesleukin", "opd": "Methotrexate", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "3155eccf-fdc9-4538-88ea-81407700fb48", "choice_type": "single"} {"question": "Facial muscles are derived from", "exp": null, "cop": 2, "opa": "1st branchial arch", "opb": "2nd branchial arch", "opc": "3rd branchial arch", "opd": "4th branchial arch", "subject_name": "Anatomy", "topic_name": null, "id": "7a2a45d3-5e29-4139-be6e-8d4d6b13f17f", "choice_type": "single"} {"question": "Sphincter and dilator pupillae develop from", "exp": "Muscles of the iris (sphincter and dilator papillae) and myoepithelial cells of the sweat glands are derived from ectoderm.Ref: Human Embryology; Inderbir Singh; Tenth edition; Page no:113", "cop": 3, "opa": "Mesoderm", "opb": "Surface ectoderm", "opc": "Neuroectoderm", "opd": "Endoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "56202708-1dc9-4915-8914-01b46d6bf4a6", "choice_type": "single"} {"question": "Prognosis of poocaval shunt depends on", "exp": "Prognosis of poocaval shunt depend on child's criteria ( Bilirubin, albumin, ascites, PT, encephalopathy) Ref: Sabiston 20th edition Pgno : 1436", "cop": 4, "opa": "Serum bilirubin", "opb": "Serum albumin", "opc": "Refractory ascites", "opd": "Type of shunt", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0d0b5bcb-deb9-40dc-ac49-05a8c8d5ac82", "choice_type": "single"} {"question": "In stratified squamous epithelium, the basal layer of cells are", "exp": "Stratified squamous epithelium Superficial layer - squamous Middle layer - Cuboidal Basal layer - Columnar Only one layer is in contact with the basement membrane, remaining layers adhere to each other maintaining the integrity. Ref: IB Singh textbook of histology 6e pg 45.", "cop": 4, "opa": "Squamous", "opb": "Cuboidal", "opc": "Columnar", "opd": "Cuboido columnar", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ae96a3f8-d556-4db4-a3a7-675be062ab82", "choice_type": "single"} {"question": "In femoral triangle the most medial structure seen is", "exp": "Femoral canal (Femoral sheath)\n                      -        Medial compartment\n\n   Opening - Femoral ring\n   Content - Lymph nodes of Cloquet/Rosenmuller, Lymphatics, fat, areolar tissue.\n\n -        Intermedius compartment\n\n   Content - femoral vein\n\n -        Lateral compartment\n\n   Content - femoral artery, femoral branch of genitofemoral nerve\n\n \n Femoral ring Formation\n-        Anterior - Inguinal ligament\n-        Medial - Lacunar ligament\n-        Posterior - Pectineus with fascia\n-        Lateral - septum separating it from femoral vein", "cop": 1, "opa": "Lymphatics", "opb": "Artery", "opc": "Vein", "opd": "Nerve", "subject_name": "Anatomy", "topic_name": null, "id": "2d18a233-191d-45bd-9037-ed90e6437e97", "choice_type": "single"} {"question": "Second constriction of oesophagus lies at the level of", "exp": "(A) (Where aortic arch Crosses) (282-BDC-16(tm))CONSTRICTIONSNormally the oesophagus shows 4 constrictions at the following levels1. At its beginning 15 cm/6 inch form the incisor teeth where it is crossed by cricopharyngeus muscles2. Where it is crossed by the aortic arch, 22,5cm /19 inch from the incisor teeth3. Where it is crossed by the left bronchus, 27.5cm /11 inch from the incisor teeth4. Where it pierces the diaphragm 37.5 cm/15 inch from the incisor teethOESOPHAGUS* About 25 cm long (10 inch)* The pharyngo-oesophageal junction is the commoned part of the alimentary canal except for the vermiform appendix* It passes through the diaphragm at the level of the 10th thoracic vertebra to join the stomachImportant features of esophagus* Epithelium is stralified squamous non * keratinized epithelium* Muscularis mucosa contains only longitudinal layer and no circular layer* Mucosa is the toughest and strongest layer *** Serosa is absent* Muscmaris extern is made up skeletal muscle fibre only in the upper ihird, smooth muscle only in the lower third and both types of muscle fibres in middle third. At uppen end the longitudinal coat split into two bundles and the triangular interval between them is called Laimer's triangle which is filled with circular muscle fibers* Extent of esophagus is -C6 -T i j* Trachea bifurcates at carina, at the level of lower border of T4 or T4-T5 disc spaces* Oesophageal opening transmits1. Oesophagus2. Gastric or vagus nerve3. Oesophageal branches of the left gastric artery. With some oesophageal veins* Arterial supply- Upper third -inferior thyroid artery **- Middle third - Oesophageal branches of the ** descending thoracic aorta- Lower third - Left gastric artery **", "cop": 1, "opa": "Where aortic arch crosses", "opb": "Bronchi", "opc": "Pharynx", "opd": "Where esophagus pierces the diaphragm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "829b3331-e0cb-4fdd-b2a1-a37c2bcdb44b", "choice_type": "single"} {"question": "Aerial anastomosis around the shoulder is between", "exp": "-Aerial anastomosis around the scapula is principally formed by the first pa of subclan and third pa of axillary aeries. -These anastomosis takes place at 2 sites :around the body of the scapula and over the acromion process of the scapula. -If the subclan and axillary aeries are blocked anywhere between these 2 sitesscapular anastomosis serves as a potential pathway of collateral circulation to ensure adequate blood supply to the upper limb -Reference: Textbook of anatomy,Upper limb and thorax, Vishram Singh, 2nd editon, page no.51", "cop": 2, "opa": "2nd pa of subclan aery with 2nd pa of axillary aery", "opb": "1st pa of subclan aery with 3rd pa of axillary aery", "opc": "3rd pa of subclan aery with 1st pa of axillary aery", "opd": "3rd pa of subclan aery with 3rd pa of axillary aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "6a7aab20-a848-4a0e-baeb-e8091cffe795", "choice_type": "single"} {"question": "Innermost layer of retina is composed of", "exp": null, "cop": 4, "opa": "Bipolar cells", "opb": "Amacrine cells", "opc": "Rods and cones", "opd": "Ganglionic cells", "subject_name": "Anatomy", "topic_name": null, "id": "a6f14806-ad0b-411e-a270-e8239be6c7f9", "choice_type": "single"} {"question": "MCH restriction to antigen presentation is not done for", "exp": "Ref Robbins 9/e p231-233 Immune Recognition of Allografts Rejection of allografts is a response mainly to MHC molecules, which are so polymorphic that most individuals in an outbred population differ in at least some of the MHC molecules they express (except, of course, for identical twins). There are two main mechanisms by which the host immune system recognizes and responds to the MHC mol- ecules on the graft (Fig. 4-23): * Direct recognition. Host T cells directly recognize the allo- geneic (foreign) MHC molecules that are expressed on graft cells. Direct recognition of foreign MHC seems to violate the rule of MHC restriction, which states that in every individual, all of the T cells are educated to recog- nize foreign antigens displayed by only that individual's MHC molecules. It is postulated that allogeneic MHC molecules (with any bound peptides) structurally mimic self MHC and foreign peptide, and so direct recognition of the allogeneic MHC is essentially an immunologic cross-reaction. Because DCs in the graft express high levels of MHC as well as costimulatory molecules, they are believed to be the major culprits contributing to direct recognition. The most impoant consequence of direct recognition is the activation of host CD8+ T cells that recognize class I MHC (HLA-A, -B) molecules in the graft. These T cells differentiate into CTLs, which kill the cells in the graft. Host CD4+ helper T cells may be trig- gered into proliferation and cytokine production by rec- ognition of donor class II MHC (HLA-D Indirect recognition. In this pathway, host CD4+ T cells recognize donor MHC molecules after these molecules are picked up, processed, and presented by the host's own APCs. This sequence is similar to the physiologic processing and presentation of other foreign (e.g., microbial) antigens. The activated CD4+ T cells then recognize APCs displaying graft antigens and secrete cytokines that induce inflammation and damage the graft. The indirect pathway is also involved in the pro- duction of antibodies against graft alloantigens; if these antigens are proteins, they are picked up by host B cells, and peptides are presented to helper T cells, which then stimulate antibody responses.", "cop": 4, "opa": "Killing of viruses by cytotoxic cells", "opb": "Killing of bacteria by helper cells", "opc": "T cells activation in autoimmunity", "opd": "Graft rejection", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7c6ffe91-23ca-4fb0-b116-05a8470f2af8", "choice_type": "single"} {"question": "Antibody used in treatment of RSV infection", "exp": "Ref Harrison 19 th ed pg 923,1206 Palivizumab is a recombinant humanized,monoclo mon IgG antibody directed against the RSV fusion protein.", "cop": 2, "opa": "Omalizumab", "opb": "Palivizumab", "opc": "Rituximab", "opd": "Daclizumab", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "39939525-0cdc-46b4-9a5d-91769c83484d", "choice_type": "single"} {"question": "In walking, gravity tends to tilt pelvis and trunk to the unsuppoed side, major factor in preventing this unwanted movements", "exp": "Gluteus medius and minimus prevent the tilting of pelvis on the unsuppoed side Gluteus medius and minimus supplied by superior gluteal nerve", "cop": 4, "opa": "Adductor muscles", "opb": "Quadriceps", "opc": "Gluteus maximus", "opd": "Gluteus medius and minimus", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "da26b995-224a-49ba-adce-e461772a1f97", "choice_type": "single"} {"question": "The blood supply to femoral head is mostly by", "exp": "The blood supply of the Femoral Head is derived mainly from retinacular aeries which are the branches of Medial Circumflex Femoral Aery .", "cop": 2, "opa": "Lateral circumflex femoral aery", "opb": "Medial circumflex femoral aery", "opc": "Ligamentum teres aery", "opd": "Obturator aery", "subject_name": "Anatomy", "topic_name": "Lower limb 1", "id": "90e0572c-6693-43ea-b7ad-4115207cbf8a", "choice_type": "single"} {"question": "One of the following nerves is not related to parotid gland", "exp": "Posterior superior alveolar nerve is not related to parotid gland.", "cop": 4, "opa": "Temporal branch of facial nerve", "opb": "Zygomatic branch of facial nerve", "opc": "Buccal branch of facial nerve", "opd": "Posterior superior alveolar branch of maxillary nerve", "subject_name": "Anatomy", "topic_name": null, "id": "e29a0981-5c4d-48bc-8ad2-79062279da6d", "choice_type": "single"} {"question": "In inversion of foot plantar surface faces", "exp": "Eversion:movement in which the lateral border of the foot is elevated,so that the sole faces laterally. Inversion:movement in which the medial border of the foot is elevated,so that the sole faces medially. In eversion and inversion,the entire pa of the foot below the talus moves together. Inversion is accompanied by plantar flexion of the foot and adduction of the forefoot. Eversion is accompanied by the dorsiflexion of the foot and adduction of the forefoot. JOINTS TAKING PA:- Subtalar Talocalcaneonavicular Transverse talar AXIS:- These movements takes place around an oblique axis which runs forwards,upwards and medially,passing from the back of the calcaneum, through sinus tarsi,to emerge at the superomedial aspect of the neck of the talus. The obliquity of the axis pay accounts for the adduction,abduction,plantar flexion and dorsiflexion which are associated with these movements. RANGE:- Inversion is more free than eversion The range of movements is increased in plantar flexion. MUSCLES PRODUCING MOVEMENTS:- Inversion :Tibialis anterior Tibialis posterior,FHL ,FDL eversion: peroneus longus and brevis {Reference:BDC 6E}", "cop": 2, "opa": "Lateral", "opb": "Medial", "opc": "Superiorly", "opd": "Inferiorly", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "c1441e5c-c82c-49a4-ab9a-5b3dc48d5de7", "choice_type": "single"} {"question": "Labourer's nerve is", "exp": "(A) Median # MEDIAN NERVE controls the coarse movements of the hands, as it supplies most of the long muscles of the front of the forearm and therefore called the 'labourer's nerve'.EPONYMOUS NAMENERVE* Vidian nerveNerve of Pterigoid canal* Musician's nerveUlnar nerve* Labourer's nerveMedian nerve* Arnold's nerve or Alderman's N.Auricular branch of vagus* Nerve of Bell or Long thoracic N.Nerve to serratus anterior (Bell's palsy = LMN paralysis of Facial Nerve)* Nerve ErigentesParasympathetic outflow from Sacral plexus - S2,3,4* Nerve of KuntzGrey ramus running upwards from 2nd thoracic ganglion to 1st thoracic nerve* Jacobson's nerveTympanic branch of Glossopharyngeal nerve* Hering's nerveNerve transmitting impulses from carotid bodies to glossopharyngeal nerve* Thickest cranial nerveTrigeminal nerve* Thickest cutaneous nerveGreater occipital nerve", "cop": 1, "opa": "Median", "opb": "Ulnar", "opc": "Radial", "opd": "Sciatic", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "83551fd5-daa7-46c8-b8cd-1a63708e2707", "choice_type": "single"} {"question": "Medical management of hydatid disease is indicated in", "exp": "Chemotherapy without definitive resection or drainage is only considered for Widely disseminated disease Patients with poor surgical risk", "cop": 4, "opa": "Pregnancy", "opb": "Infected hydatid cyst", "opc": "Moribund patients", "opd": "Multiple peritoneal cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fa6fcdf2-4331-4493-82e9-202a923a2716", "choice_type": "single"} {"question": "Posterior ethmoidal sinus opens into", "exp": "The posterior ethmoidal air sinus consisting of 1-7 air cells open into the superior meatus of the nose. It is supplied by the posterior ethmoidal nerve and vessels and the orbital branches of pterygopalatine ganglion. Ref BDC volume 3,6th edition pg 246", "cop": 1, "opa": "Superior nasal meatus", "opb": "Middle nasal meatus", "opc": "Inferior nasal meatus", "opd": "Sphenoethmoidal recess", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "999e1376-c34d-48f2-b3a2-6ab4ee0a2e72", "choice_type": "single"} {"question": "Third ventricle is derived from", "exp": "C i.e. ThalamencephalonThe pa of the diencephalon of the brain that includes the thalamus, pineal gland, and adjacent structuresThalamencephalon also called thalamic region is a complex structure comprising thalamus (in the wider sense of the term thalamus, i.e. dorsal thalamus, or thalamus proper, plus subthalamus, or ventral thalamus) and several adjacent structures: epithalamus and metathalamusDEVELOPMENT:The cavity of the thalamencephalon opens behind into the cavity of the middle cerebral vesicle, and in front communicates with the hollow rudiments of the cerebral hemispheres, and eventually it becomes the cavity of the third ventricle.The floor of the thalamencephalon is ultimately developed into the optic chiasma, pa of the optic nerves, and the infundibulum.The latter comes in contact with a process from the mouth, uniting with which it ultimately forms the pituitary body.From the posterior pa of the roof of the thalamencephalon is developed the pineal gland .The anterior pa of the roof of the thalamencephalon becomes very thin, and its place is finally occupied by a thin membrane containing a vascular plexus, which persists in the roof of the third ventricle {choroidplexus).From the sides of the thalamencephalon, which become extremely thickened, are developed the optic thalami.", "cop": 3, "opa": "Mesencephalon", "opb": "Rhombencephalon", "opc": "Thalamencephalon", "opd": "Telencephalon", "subject_name": "Anatomy", "topic_name": null, "id": "57ce3aa4-8ab7-44cd-810f-8606e848fc64", "choice_type": "single"} {"question": "The nerve of the 6th arch is", "exp": "Description Human embryology Inderbeir Singh tenth edition Page no 133Occipital somites: laryngeal muscles from 4th to 6th arches supplied by the recurrent laryngeal nerve.", "cop": 4, "opa": "Superior laryngeal nerve", "opb": "Internal laryngeal nerve", "opc": "External laryngeal nerve", "opd": "Recurrent laryngeal nerve", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "93b31e1f-dca3-4af7-8dd3-543d25e90b77", "choice_type": "single"} {"question": "Anal canal is NOT supplied by", "exp": "Middle rectal aery supplies the rectum, but 'not' the anal canal.", "cop": 4, "opa": "Superior rectal aery", "opb": "Inferior rectal aery", "opc": "Median sacral aery", "opd": "Middle rectal aery", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "418d1b12-0278-4852-9992-a195cb7bfce8", "choice_type": "single"} {"question": "General visceral fibres do not supply", "exp": "Skeletal muscle is not supplied by general visceral fibres Inderbir Singh&;s textbook of human Histology Seventh edition", "cop": 2, "opa": "Smooth muscles", "opb": "Skeletal muscles", "opc": "Cardiac muscles", "opd": "Glands", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a80adf07-5438-4436-a8e1-c2bd790f6393", "choice_type": "single"} {"question": "In a complete section of the ulnar nerve at the wrist, disability of the hand results from the paralysis of", "exp": "Interossei involve all digits hence produce complete disability. Hypothenar muscles are paralyzed but affect only the muscles of the little finger. Branches to FDP and FCU are given off in the forearm and hence intact in a wrist lesion.** Both interossei, hypothenar effected, question asks which causes more disability hence interosseiReference: Chaurasia; 6th edition", "cop": 3, "opa": "Flexor carpi ulnaris", "opb": "Flexor digitorum profundus", "opc": "Interossei", "opd": "Hypothenar muscles", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f7323a98-6d12-438e-b8f3-0948dc0d6bd0", "choice_type": "single"} {"question": "Pneumatocytes lines the", "exp": "(Alveoli) (83-M. Kaul histology 3rd) (221- LB.Singh 5th)Respiratory system - Histology* Trachea - lined by pseudostratified ciliated columnar epithelium* Intrapulmonary Bronchus - lined by pseudostratified ciliated columnar epithelium* Terminal Bronchiole - lined by simple columnar epithelium* Respiratory Bronchiole - lined by cuboidal epithelium* Atria, alveolar ducts and alveoli - lined with squamous epitheliumALVEOLI - The main support of the alveoli is provided by elastic fibres* Majority of cells lining the alveoli are the squamous cells or type 1 pneumocytes. Few are larger cells or type II pneumocytes. Type II cells secrete the surfactant which lowers surface tension and prevents alveoli from collapsing* The exchange between the blood in the capillaries and air in the alveoli takes place through(a) Cytoplasm of endothelial cell of a capillary(b) Basement membrane of the capillary(c) Basement membrane of the alveolus(d) Cytoplasm of the epithelial cells of the alveolus* In CHF, heart failure cells are present in the sputum. These cells are the alveolar macrophages, containing hemosiderin of the red blood cells from the ruptured capillaries.", "cop": 4, "opa": "Segmental bronchiole", "opb": "Terminal branchioles", "opc": "Respiratory bronchioles", "opd": "Alveoli", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "c0fbad1f-6c23-4b0f-9459-901a73c02641", "choice_type": "single"} {"question": "Sure sign of malignancy is", "exp": "Ref Robbins 8/e p269; 9/e p272 CHARACTERISTICS OF BENIGN AND MALIGNANT NEOPLASMS Nothing is more impoant to the patient with a tumor than being told: \"It is benign.\" In general, benign tumors appear to be genetically \"simple,\" harboring fewer muta- tions than cancers, and genetically stable, changing little in genotype over time. The latter feature probably explains why benign tumors such as lipomas and leiomyomas transform to malignancies rarely, if at all. In practice, the determination of benign versus malignant is made with remarkable accuracy using long-established clinical and anatomic criteria, but some neoplasms defy easy character- ization. Ceain features may indicate innocence, and others may indicate malignancy. Such problems are not the rule, however, and there are four fundamental features by which benign and malignant tumors can be distinguished: dif- ferentiation and anaplasia, rate of growth, local invasion, and metastasis. Differentiation and Anaplasia Differentiation and anaplasia are characteristics seen only in the parenchymal cells that constitute the transformed elements of neoplasms. The differentiation of parenchymal tumor cells refers to the extent to which they resemble their normal forebears morphologically and functionally. * Benign neoplasms are composed of well-differentiated cells that closely resemble their normal counterpas. A lipoma is made up of mature fat cells laden with cytoplasmic lipid vacuoles, and a chondroma is made up of mature cailage cells that synthesize their usual cailaginous matrix--evidence of morphologic and functional differentiation. In well-differentiated benign tumors, mitoses are usually rare and are of normal configuration. * Malignant neoplasms are characterized by a wide range of parenchymal cell differentiation, from sur- prisingly well differentiated (Fig. 5-3) to completely in sheets, with total loss of communal structures, such as glands or stratified squamous architecture. The more differentiated the tumor cell, the more com- pletely it retains the functional capabilities of its normal counterpas. Benign neoplasms and even well-differenti- ated cancers of endocrine glands frequently elaborate the hormones characteristic of their origin. Well-differentiated squamous cell carcinomas produce keratin (Fig. 5-3), just as well-differentiated hepatocellular carcinomas secrete bile. In other instances, unanticipated functions emerge. Some cancers may elaborate fetal proteins not produced by comparable cells in the adult. Cancers of nonendocrine origin may produce so-called ectopic hormones. For example, ceain lung carcinomas may produce adrenocor- ticotropic hormone (ACTH), parathyroid hormone-like hormone, insulin, glucagon, and others. More is said about these phenomena later. Despite exceptions, the more rapidly growing and the more anaplastic a tumor, the less likely it is to have specialized functional activity. Of relevance in the discussion of differentiation and ana- plasia is dysplasia, referring to disorderly but non-neoplastic undifferentiated. For example, well-differentiated ade- nocarcinomas of the thyroid may contain normal- appearing follicles. Such tumors sometimes may be difficult to distinguish from benign proliferations. Between the two extremes lie tumors loosely referred to as moderately well differentiated. The stroma carrying the blood supply is crucial to the growth of tumors but does not aid in the separation of benign from malignant ones. The amount of stromal connective tissue does deter- mine, however, the consistency of a neoplasm. Ceain cancers induce a dense, abundant fibrous stroma (des- moplasia), making them hard, so-called scirrhous tumors. * Malignant neoplasms that are composed of undiffer- entiated cells are said to be anaplastic. Lack of differen- tiation, or anaplasia, is considered a hallmark of malignancy. The term anaplasia literally means \"back- ward formation\"--implying dedifferentiation, or loss of the structural and functional differentiation of normal cells. It is now known, however, that at least some cancers arise from stem cells in tissues; in these tumors, failure of differentiation, rather than dedifferentiation of specialized cells, accounts for their undifferentiated appearance. Recent studies also indicate that in some cases, dedifferentiation of apparently mature cells does occur during carcinogenesis. Anaplastic cells display marked pleomorphism (i.e., variation in size and shape) (Fig. 5-4). Often the nuclei are extremely hyperchromatic (dark-staining) and large resulting in an increased nuclear-to-cytoplasmic ratio that may approach 1: 1 instead of the normal 1: 4 or 1 :6. Giant cells that are considerably larger than their neighbors may be formed and possess either one enormous nucleus or several nuclei. Anaplastic nuclei are variable and bizarre in size and shape. The chromatin is coarse and clumped, and nucle- oli may be of astounding size. More impoant, mitoses often are numerous and distinctly atypical; anarchic multi- ple spindles may produce tripolar or quadripolar mitotic figures (Fig. 5-5). Also, anaplastic cells usually fail to develop recognizable patterns of orientation to one another (i.e., they lose normal polarity). They may grow proliferation. Dysplasia is encountered principally in epi- thelial lesions. It is a loss in the uniformity of individual cells and in their architectural orientation. Dysplastic cells exhibit considerable pleomorphism and often possess hyperchro- matic nuclei that are abnormally large for the size of the cell. Mitotic figures are more abundant than usual and frequently appear in abnormal locations within the epithe- lium. In dysplastic stratified squamous epithelium, mitoses are not confined to the basal layers, where they normally occur, but may be seen at all levels and even in surface cells. There is considerable architectural anarchy. For example, the usual progressive maturation of tall cells in the basal layer to flattened squames on the surface may be lost and replaced by a disordered scrambling of dark basal- appearing cells (Fig. 5-6). When dysplastic changes are marked and involve the entire thickness of the epithelium, the lesion is referred to as carcinoma in situ, a preinvasive stage of cancer (Chapter 18). Although dysplastic changes often are found adjacent to foci of malignant transforma- tion, and long-term studies of cigarette smokers show that epithelial dysplasia almost invariably antedates the appear- ance of cancer, the term dysplasia is not synonymous with cancer; mild to moderate dysplasias that do not involve the entire thickness of the epithelium sometimes regress completely, par- ticularly if inciting causes are removed.", "cop": 4, "opa": "Mitosis", "opb": "Polychromasia", "opc": "Nuclear pleomorphism", "opd": "Metastasis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "557158ce-d347-4da0-9c8c-1e662d6ab733", "choice_type": "single"} {"question": "Space of Disse is seen in", "exp": "Histology of liver * The perisinusoidal space (or space of Disse) is a narrow gap between a plate of hepatocytes and a sinusoid. * The width of this perisinusoidal space is 0.2-0.5 micrometre. * Microvilli of hepatocytes, stellate cells, interstitial fluid and collagen fibres are the major constituents of this space. Ref:- Gray's Anatomy 41st Edition; Pg Num:- 1170", "cop": 4, "opa": "Bone", "opb": "Lymph node", "opc": "Spleen", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "731a56fb-f8bf-454e-aecf-a83c1b69f03c", "choice_type": "single"} {"question": "Drug used in the management of mood stabilizer used ihe management of", "exp": "Lamotrigine is a mood stabilizer which works best in BIPOLAR DEPRESSION Lithium is a mood stabilizer which works best in BIPOLAR MANIA valproate is a mood stabilizer which works best in RAPID CYCLING Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 1, "opa": "lithium", "opb": "carbamezepine", "opc": "lamotrigine", "opd": "valproate", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "3aa304c6-3ff2-4427-951e-bad5cff3c79c", "choice_type": "single"} {"question": "Sensory supply of from external auditory meatus", "exp": "The skin lining the anterior half of the meatus is supplied by the auriculotemporal nerve, and that lining the posterior half, by the auricular branch of the vagus. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 6th edition 368", "cop": 4, "opa": "Pterygomandibular ganglion", "opb": "Geniculate ganglion", "opc": "Facial nerve nucleus", "opd": "Auriculotemporal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "818961e1-1806-439b-a1cb-ef183065ec53", "choice_type": "single"} {"question": "Peribulbar injection is given in", "exp": "Surgical spaces of the orbit are: Subperiosteal space Peripheral orbital space Central space(muscular cone or Retrobulbar space) Subcutaneous space Refer khurana 6/e", "cop": 3, "opa": "Subtenon space", "opb": "Muscle space", "opc": "Peri orbital space", "opd": "Sub periorbital space", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6845593f-14ec-4c10-b489-a0b940684e91", "choice_type": "single"} {"question": "Intercalated discs are seen in", "exp": "Ans: b) Cardiac muscleIntercalated discs are cell membranes that separate individual cardiac muscle cells from one another. Cardiac muscle fibres are made up of many individual cells connected in series and in parallel in such a way that they form permeable \"communicating junctions\"- gap junctions that allow free diffusion of ions.", "cop": 2, "opa": "Iris", "opb": "Cardiac muscle", "opc": "Musculotendinous endings", "opd": "Nerve bundles", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "9e421cdb-5d89-4a14-a14f-aeca71749446", "choice_type": "single"} {"question": "Structure held by forceps is seen in", "exp": "Appendix Epiploica is one of the numerous pouches of the peritoneum filled with fat and attached to the colon.", "cop": 3, "opa": "Stomach", "opb": "Appendix", "opc": "Colon", "opd": "Duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "8f8f4df6-a6a5-48fa-b397-172dc17eb885", "choice_type": "single"} {"question": "Sec 84 deals with", "exp": "McNaughten's rule IPC sec 84: Nothing is an offence which is done by a person who, at the time of doing it, by the reason of unsoundness of mind, is incapable of knowing the nature of the act, or that he is doing, what is either wrong or contrary to law. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 369", "cop": 3, "opa": "Testamentary capacity", "opb": "Management of propey", "opc": "McNaughten's rule", "opd": "Consent", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "4c3bf3f0-a740-4798-9023-352b8f4350d9", "choice_type": "single"} {"question": "Facial skeleton develops from", "exp": "The viscerocranium forms the facial skeleton and the major pa of which develops from mesenchyme derived from 1st and 2nd pharyngeal arches.The lacrimal and nasal bones are derived from neural crest cells. The paraxial mesoderm undergoes segmentation to form somitomeres and somites that fuher differentiate into sclerotome, myotome, and dermatome. The intermediate mesoderm forms most of the genito-urinary system -eg; kidneys, testes, ovaries The lateral plate mesoderm forms body wall and body cavities. Reference: Textbook of clinical embryology, Vishram Singh,1st edition,page no.94,49", "cop": 1, "opa": "Neural crest", "opb": "Paraxial mesoderm", "opc": "Intermediate mesoderm", "opd": "Lateral plate mesoderm", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "44b77c88-2e49-4e8f-8243-35e01b58c459", "choice_type": "single"} {"question": "Dilator papillae are supplied by", "exp": "Dilator papillae are supplied by sympathetic fibers, which arises from the inter medio lateral horn of spinal cord segment of T-1 These pre-ganglionic T-1 sympathetic fibersclimbs up the cervical sympathetic chain and synapse in the superior (highest)cervical ganglion. Postganglionic fibers makes sympathetic plexus around the internal carotid aery and reach the dilator papillae muscle. Ref: Gray's 39e/p-227", "cop": 3, "opa": "Oculomotor nerve", "opb": "Sympathetic fibers from the fronto - orbital branch of trigeminal nerve", "opc": "Postganglionic sympathetic fibers from cervical sympathetic chain", "opd": "Postganglionic parasympathetic fibers", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "548c4d6b-349a-465c-996a-5618000741d1", "choice_type": "single"} {"question": "Oxigen are used as specific antidotes in", "exp": "Oximes These are specific antidotes. The available oxigen are Diacetyl monoxime. 2- pyridine Aldoxime Methiodide Pralidoxime chloride Action: Oximes react with phosphate moiety of organophosphate- AchE complex and get phosphorilated. So AchE is released from the complex and thus reactivated. The oximes decreases the muscarinic, nicotine and CNS effects of organophosphates within 10-40 minutes Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 450", "cop": 3, "opa": "Alcohol poisoning", "opb": "Mercury poisoning", "opc": "OP poisoning", "opd": "Cyanide poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "cd80d974-91bc-4c0b-b708-089cbee00202", "choice_type": "single"} {"question": "The most commonly used resuscitation fluid in burns is", "exp": "The most common fluid used is Ringer lactate/Hamann's solution Ringer lactate is a mixture of sodium chloride, sodium lactate, potassium chloride, calcium chloride in water. Crystalloids are said to be as effective as colloids for maintaining the intravascular volume and are given during initial 24 hrs Colloids should ideally be given after the first 12 hrs of burn because before this period, the massive fluid shift cause protein to leak out of cells.", "cop": 2, "opa": "Normal saline", "opb": "Ringer lactate", "opc": "Hypeonic saline", "opd": "Human albumin solution", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "32155625-1016-41a0-9c23-07417011117b", "choice_type": "single"} {"question": "Principal blood supply to tonsil is from", "exp": "Aerial supply of tonsil: Tonsillar branch of facial aery (Principal blood supply) Dorsalis linguae branches of lingual aery. Ascending palatine, a branch of facial aery. Ascending pharyngeal, a branch of external carotid aery. Greater palatine (descending palatine), a branch of maxillary aery.", "cop": 4, "opa": "Lingual aery", "opb": "Descending palatine aery", "opc": "Ascending pharyngeal aery", "opd": "Facial aery", "subject_name": "Anatomy", "topic_name": "Abdomen: Miscellaneous", "id": "3c482f83-b625-40fa-af8d-a04578c6e191", "choice_type": "single"} {"question": "Torus Aoicus is present in", "exp": "Torus aoicus is the prominent region of the right atrial septum, which marks the projection of the non-coronary aoic sinus into the right atrial wall. The bulge is superior to the coronary sinus and anterior to the fossa ovalisReference: Vishram Singh Anatomy; 2nd edition; Page no: 265", "cop": 1, "opa": "Right Atrium", "opb": "Right Ventricle", "opc": "Left Ventricle", "opd": "Left Atrium", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "eab63da2-2bda-4add-9acf-ff10f4be051a", "choice_type": "single"} {"question": "Bullet changes it's direction by striking on some surface or object in", "exp": "Ricochet bullet Bullet changes it's direction by striking on some surface or object. Ricochet occurs when it strikes on some intermediate objects before entering the body. Due to ricochet the bullet may be deformed and more superficially placed in the body. The external wound of entry will be larger, triangular or cruciate with irregular margins. The paicles of the surface on which the bullet is deflected eg: paint, fibre, mud, etc. may be sticking on the bullet. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 141", "cop": 1, "opa": "Ricochet bullet", "opb": "Souvenir bullet", "opc": "Rubber bullet", "opd": "Hollow point bullet", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "aae98a8e-b7d4-497e-a0af-4029d8a6570c", "choice_type": "single"} {"question": "Commonest cause of periumbilical pain after 30 min.of TURP done under spinal anesthesia with Bupivacaine", "exp": "Perforation of bladder is one of the complications of TURP. It can present with periumblical pain. This pt. experiences pain 30 minutes after TURP. This is because he is under spinal anesthesia. In this pt. the effect of spinal anesthesia terminates 30 min. after the operation. Now he is able to perceive the pain of bladder perforation. Meteorism - is distention of the abdomen or intestines by gas. This is seen in Renal injury but not in TURP. Ref : Bailey & Love 25/e p1352", "cop": 2, "opa": "Meteorism", "opb": "Perforation of bladder", "opc": "Recovery from bupivacaine anaesthesia", "opd": "Mesentery aery ischemia", "subject_name": "Anatomy", "topic_name": "Urology", "id": "d6097a8b-cd72-4457-b2a4-c36be6d0a35d", "choice_type": "single"} {"question": "Erb's palsy involves", "exp": "ERB'S PARALYSIS:- upper plexus injury.Caused by the forceful widening of the angle between the head and shoulder which may occur by traction of the arm during the bih of a child or by fall on the shoulder.Involves upper trunk - C5, C6 roots. Leads to typical deformity in the limb- policeman's tip hand/ poer's tip hand. The arm hangs by the side, adducted and medially rotated. DISABILITY: The following movements are lost. Abduction and lateral rotation of the arm at shoulder joint flexion and supination of the forearm. biceps and supinator jerks are lost. sensations are lost over a small area over the lower pa of the deltoid. REF: BD Chaurasia 7th edition page no: 59.", "cop": 1, "opa": "C5 C6", "opb": "C8 T1", "opc": "T1 T2", "opd": "C6 C7", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f4ae5d78-4f1c-401a-b449-ba7a6a5fb47a", "choice_type": "single"} {"question": "The most common cause of delayed umbilical cord separation is", "exp": "Leukocyte adhesion deficiency may present with recurrent bacterial infections, defects in neutrophil adhesion, and a delay in umbilical cord sloughing. All other options given are various umbilical pathologies, but not related to delayed sloughing of cord", "cop": 2, "opa": "Raspbery tumour", "opb": "Leukocyte adhesion deficiency", "opc": "Patent urachus", "opd": "Umbilical granuloma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9da399ac-b899-400f-8a5e-71396283e2d2", "choice_type": "single"} {"question": "Russell bodies are seen in", "exp": "They are homogeneous eosinophillic inclusions that result from hugely distended endoplasmic reticulum", "cop": 4, "opa": "A. Lymphocytes", "opb": "B. Neutrophils", "opc": "C. Macrophages", "opd": "D. Plasma cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5da018f7-081b-4cca-8654-06c2f20ab107", "choice_type": "single"} {"question": "Nikshay software is used for", "exp": "Nikshay software is a web based solution for monitoring TB patients under Revised National Tuberculosis Control Programme (RNTCP). It was developed by National Informatics Center (NIC).", "cop": 4, "opa": "Filaria", "opb": "Malaria", "opc": "Kala azar", "opd": "Tuberculosis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1efce5e3-3424-4175-b5ed-b15d8c9e30ab", "choice_type": "single"} {"question": "Tongue muscle develop from", "exp": "Occipital myotomes forms intrinsic and extrinsic muscler of fongus.", "cop": 3, "opa": "Echoderm", "opb": "Brachial arch", "opc": "Occipital myotomer", "opd": "Septum transversum", "subject_name": "Anatomy", "topic_name": null, "id": "bb43b0ce-2eee-4cfa-bf27-e5d0cbd8bb8a", "choice_type": "single"} {"question": "Medial branch of External Carotid aery is", "exp": "Branches of the External carotid aery:Anterior: Superior Thyroid, Lingual and FascialPosterior: Occipital and Posterior auricularMedial: Ascending Pharyngeal aeryReference: Chourasia; 6th edition; 101 page", "cop": 1, "opa": "Ascending Pharyngeal aery", "opb": "Lingual aery", "opc": "Occipital aery", "opd": "Facial aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "17be09c5-1ec9-40b7-b33f-1fbd0cbf42be", "choice_type": "single"} {"question": "Thrombosis of the following cerebral vessels leading to the Hemiplegia by", "exp": "(Middle cerebral) (388-BDC-3- 4th edition)* HEMIPLEGIA - is a common condition. It is an UMN type of paralysis of one half of the body including the face* It is usually due to an internal capsule lesion caused by thrombosis of one of the lenticulostriate branches of the middle cerebral artery (Cerebral thrombosis)* Wallenberg's syndrome (lateral medullary syndrome) caused by thrombosis of the posterior inferior cerebral artery", "cop": 2, "opa": "Anterior cerebral", "opb": "Middle cerebral", "opc": "Posterior cerebral", "opd": "Lateral cerebral", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "01e28d60-2bb4-438a-b5a2-f19e2df8dc19", "choice_type": "single"} {"question": "Most sensitive test for screening of \" SLE\" is", "exp": "Ref Robbins 9/e p219, 8/e p214 ,7/e p228 Spectrum of Autoantibodies in SLE Antibodies have been identified against a host of nuclear and cytoplasmic components of the cell that are specific to neither organs nor species. Another group of antibodies is directed against surface antigens of blood cells, while yet another is reactive with proteins in complex with phospho- lipids (antiphospholipid antibodies) (Chapter 3). * Antinuclear antibodies. ANAs are directed against several nuclear antigens and can be grouped into four catego- ries: (1) antibodies to DNA, (2) antibodies to histones, (3) antibodies to nonhistone proteins bound to RNA, and (4) antibodies to nucleolar antigens. Table 4-10 lists several autoantibodies, including ANAs, and their asso- ciation with SLE as well as with other autoimmune dis- eases, to be discussed later. The most widely used method of detecting ANAs is the indirect immunofluo- rescence assay (IFA), which screens for autoantibodies that bind to a variety of nuclear antigens, including DNA, RNA, and proteins. Four staining patterns are seen with IFA: homogeneous or diffuse, rim or periph- eral, speckled, and nucleolar. While each pattern can be suggestive of the presence of specific autoantibodies, the strength of these associations is limited and should not be relied on. ANA testing by IFA is extremely sensitive, as more than 95% of patients with SLE will test positive, but the test's specificity is quite limited, because patients with other autoimmune diseases, chronic infections, and cancer will test positive as well. Fuhermore, ANAs are seen in approximately 5% to 15% of healthy people, and the incidence increases with age. Recently, the IFA has been replaced in many clinical laboratories by multiplex flow cytometry immunoassays that can simultaneously test for multiple specific autoantibodies, but these assays may lack the sensitivity of the IFA. Antibodies to double- stranded DNA (dsDNA) and the so-called Smith (Sm) antigen can be detected by ELISA or multiplex flow methods and are specific for SLE. * Other autoantibodies. Antibodies against blood cells, including red cells, platelets, and lymphocytes, are found in many patients. Antiphospholipid antibodies are present in 40% to 50% of patients with lupus and react with a wide variety of proteins in complex with phospholipids. Some bind to cardiolipin antigen, used in serologic tests for syphilis, so patients with lupus may have a false-positive test result for syphilis. Antiphos- pholipid antibodies contribute to coagulation abnormal- ities, which are described below. Mechanisms of Tissue Injury Regardless of the exact sequence by which autoantibodies are formed, they are likely to be the mediators of tissue injury, probably through multiple mechanisms. * Most organ damage in SLE is caused by immune complex deposition. Skin and kidney biopsies from patients with SLE typically demonstrate diffuse and heavy granular deposits of complement and immunoglobulin. Autoan- tibodies complexed with DNA can be detected as well. These deposits of immune complexes had been thought to cause tissue damage by activating the classical com- plement pathway (type III hypersensitivity); 75% of patients will have reduced serum levels of C3 and C4 at the time of SLE flares, presumably because complement is being activated and consumed faster than it can be produced. However, people and rodents deficient in C1q are not protected from SLE and actually can spon- taneously develop SLE, raising the possibility that complement-independent mechanisms may also con- tribute to tissue damage. * Autoantibodies of different specificities contribute to the pathology and clinical manifestations of SLE (type II hyper- sensitivity). Autoantibodies against red cells, white cells, and platelets opsonize these cells and lead to their phagocy- tosis, resulting in cytopenias. Autoantibodies against various phospholipids lead to increased thrombosis in patients, with varied clinical consequences, including recurrent spontaneous aboion and thrombotic epi- sodes. These disorders are pa of the antiphospholipid syndrome. Paradoxically, these antibodies interfere with clotting tests and are actually called \"lupus anticoagu- lants.\" Autoantibodies are also produced against clot- ting factors such as thrombin, and these too may contribute to clotting disorders. Autoantibodies against central nervous system receptors for various neurotransmit- ters have been implicated in the neuropsychiatric com- plications of the disease. * There is no evidence that ANAs can permeate intact cells. However, if cell nuclei are exposed, the ANAs can bind to them. In tissues, nuclei of damaged cells react with ANAs, lose their chromatin pattern, and become homogeneous, to produce so-called LE bodies or hema- toxylin bodies. An in vitro correlate of this is the LE cell, a neutrophil or macrophage that has engulfed the dena- tured nucleus of another injured cell. When blood is withdrawn and agitated, a number of leukocytes are sufficiently damaged to expose their nuclei to ANAs, with secondary complement activation; these antibody- and complement-opsonized nuclei are then readily phagocytosed. Although the LE cell test is positive in as many as 70% of patients with SLE, it is now largely of historical interest.", "cop": 3, "opa": "LE phenomenon", "opb": "Rheumatoid ahritis", "opc": "Anti_nuclear factor", "opd": "Double stranded DNA test", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b22b42db-a810-4eea-95f8-47df4a7b470e", "choice_type": "single"} {"question": "Tardy ulnar nerve palsy is due to", "exp": "Tardy ulnar nerve palsy is due to cubitus valgus. Fracture of the lateral condyle of humerus in the long run can lead to complications such as Cubitus valgus. Friction neuritis of the ulnar nerve as it moves over the medial epicondayle every time the elbow is flexed and extended may result in a late ulnar nerve palsy called as 'TARDY ULNAR PALSY'.", "cop": 1, "opa": "Cubitus valgus", "opb": "Fixation of the nerve in the groove by osteoahritis", "opc": "Excision of elbow joint", "opd": "Fracture of internal condyle", "subject_name": "Anatomy", "topic_name": "Peripheral nerve injuries", "id": "1c871c8c-bd2e-441c-b3cf-33acbbfac88b", "choice_type": "single"} {"question": "Oogonia are derived from", "exp": "Inderbir Singh&;s; Human Histology; Seventh edition; Pg 346The stem cells from which ova are derived are called Oogonia. These are large round cells present in the coex of the ovary. Oogonia are derived from the primordial germ cells that are formed in the region of the yolk sac and migrate into the developing ovary", "cop": 1, "opa": "Yolk sac", "opb": "Germinal epithelium", "opc": "Chorion", "opd": "Mesoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9d58d1f7-3c88-41e0-a4f8-dbc854935a84", "choice_type": "single"} {"question": "The abductor of vocal cord is", "exp": "Ans. a (Posterior cricoarytenoid) (Ref BDC vol. 3/4th/243)Posterior Cricoarytenoid is known to be the only abductor of the larynx. It opens space between the vocal cords (abduct) by rotating the arytenoids laterally (abduct), causing the vocal cords to separate opening the rima glottidis. Posterior cricoarytenoid muscle is called the safety muscle because ail the intrinsic muscles are adductors of the vocal cords except posterior cricoarytenoids which are abductors. The cricothyroid muscle is the only tensor of the larynx aiding with phonation and should not to be confused with the posterior cricoarytenoid muscles, which are the only muscles directly responsible for opening (abducting) the space between the vocal cords.Laryngeal muscleAction1.Aryepiglottic MuscleDraws the epiglottis posteriorly and downward during swallowing2.Oblique ArytenoidDraws arytenoid cartilages together, adducting vocal folds3.Transverse ArytenoidDraws arytenoid cartilages together, adducting vocal folds4.ThyroarytenoideusDraws arytenoid cartilage forward, relaxing and adducting the vocal folds5.Vocalis muscle^Relaxes segments of the vocal ligament, thereby adjusting voice pitch.Educational Points# Larynx begins at C4 & ends at C7 vertebral levels Q# The only intrinsic muscle of larynx that lies outside the laryngeal framework is Cricothyroid.LIGAMENTS OF LARYNX# The extrinsic ligaments of the larynx are those connecting the thyroid cartilage and epiglottis with the hyoid bone and the cricoid cartilage with the trachea.# The intrinsic ligaments of the larynx are those connecting several cartilages ofthe organ to each other. They are considered the elastic membrane of the larynx.A Structural ligaments - hold larynx, hyoid and trachea together1. Thyrohyoid membrane-link thyroid cartilage to hyoid bone;medial part is median thyrohyoid ligament.2. Cricothyroid membrane - links cricoid to thyroid cartilage; thickened medial and anterior part called Median cricothyroid ligament.3. Cricotracheal ligament - links cricoid to first tracheal cartilage.4. Quadrangular membrane - links arytenoid to epiglottis; lower free edge is called vestibular ligament.5. Thyroepiglottic ligament - links epiglottis to thyroid cartilage.B. Functional LigamentsConus elasticus - elastic membrane forming vibrating lips; arises from entire upper edge of arch of cricoid; attaches anteriorly to thyroid cartilage, posteriorly to vocal processes of arytenoid cartilages; upper free edges are thickened to form vocal ligaments; opening between vocal ligaments is called rima glottidis. Functions of conus elasticus: Sound production and Closing rima glottidis.", "cop": 1, "opa": "Posterior cricoarytenoid", "opb": "Lateral cricoarytenoid", "opc": "Thyroarytenoid", "opd": "Cricoarytenoid", "subject_name": "Anatomy", "topic_name": "Larynx", "id": "665a9d4c-ba44-4bf9-b513-970913ba1442", "choice_type": "single"} {"question": "Purkinje cells are situated in", "exp": "Purkinje Cells It is the characteristic cell of cerebellum.It gets stimulated by climbing fibers coming from inferior olivary nucleus .The main output of this cell is to cerebellar nuclei and is inhibitory in nature. Ref.B D Chaurasia's human anatomy.vol.3", "cop": 2, "opa": "A.Cerebral coex", "opb": "B.Molecular layer of cerebellum", "opc": "C.Granular layer of cerebellum", "opd": "D.Nucleus emboliformis", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "ea58ee71-45dc-4005-b344-2eb7041ac853", "choice_type": "single"} {"question": "Most common cause of hemobilia", "exp": "Hemobilia Bleeding into the biliary tract from an abnormal aerial source to intrahepatic biliary tract fistula Poal venous bleeding into the biliary tree is rare, minor and selflimited Aerial hemobilia is the most common source Etiology Trauma : Iatrogenic (PTC) is the most common cause, blunt trauma is more common cause than penetrating trauma Gallstones Vascular pathology : Aneurysm, angiodysplasia, Parasitic infestation, liver abscess, cholangitis Ref: Sabiston 20th edition Pgno :1472-1474", "cop": 2, "opa": "Trauma", "opb": "Iatrogenic", "opc": "Parasites", "opd": "Tumors", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0a02b0ce-30da-4799-8cab-0364c9abaf4e", "choice_type": "single"} {"question": "Sternum attached to scapula", "exp": "Sternum or chest bone is attached to scapula which is present on posterior surface with help of clavicle or collar bone so that weight of upper limb is transmitted to axial skeleton scapula,Clavicle and sternum", "cop": 2, "opa": "Manubrium", "opb": "Clavicle", "opc": "First rib", "opd": "Second rib", "subject_name": "Anatomy", "topic_name": "Osteology", "id": "3b73952f-6619-4726-9925-c7d96f94144d", "choice_type": "single"} {"question": "Best skin disinfectant for central line inseion is", "exp": "Chlorhexidine is now the disinfectant recommended for all catheter placementprocedures and for routine site cleansing during dressing changes. \"Use of antiseptic solution for skin disinfection at the catheter inseion site helps prevent catheter-related infection. Chlorhexidine-based solutions appear to be superior to both aqueous and alcohol-based povidone-iodine in reducing the risk for catheter colonization and catheter-related bloodstream infection. If there is a contraindication to chlorhexidine, tincture of iodine, an iodophor or 70 per cent alcohol can be used as alternatives", "cop": 4, "opa": "Povodine iodine", "opb": "Alcohol", "opc": "Cetrimide", "opd": "Chlorhexidine", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "37f4b92a-6ff9-4724-b012-f332c1ffee3a", "choice_type": "single"} {"question": "The following drug selectively acts on beta receptors", "exp": "Isoprenaline acts only on beta 1 and beta 2 receptors.", "cop": 2, "opa": "Dopamine", "opb": "Isoprenaline", "opc": "Nor adrenaline", "opd": "Adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "faab8fd3-31b2-4753-9e47-225b0a2a03b7", "choice_type": "single"} {"question": "Endogenous chemoattractant is", "exp": "Ref Robbins 8/e p66;7/e p56;9/e p77 C5a is a strong chemoattractant and is involved in the recruitment of inflammatory cells such as neutrophils, eosinophils, monocytes, and T lymphocytes, in activation of phagocytic cells and release of granule-based enzymes and generation of oxidants, all of which may contribute to innate immune functions or tissue ...", "cop": 1, "opa": "C5a", "opb": "Bacterial products", "opc": "Lipopolysaccharide A", "opd": "C8", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ea9cd710-e3b3-4c12-81bd-f8f5faf43992", "choice_type": "single"} {"question": "Nerve for motor function of buccinator muscle", "exp": "The buccal branch of mandibular nerve is sensory is nature and supplies the skinand mucous membrane related to the buccinator. The buccal branch of facialnerve is motor in nature and it supplies the buccinator muscle.", "cop": 3, "opa": "Hypoglossal nerve", "opb": "Glossopharyngeal nerve", "opc": "Facial nerve", "opd": "Trigeminal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "1818f6a2-b1c0-40be-bb79-d52875dea60c", "choice_type": "single"} {"question": "The efferent limb of cremaster reflex is carried by", "exp": "CREMASTER REFLEX: When we touch upper medial thigh in males, cremaster muscle contracts & pull the ipsilateral testicle towards inguinal canal. Afferent sensory information is carried by Femoral branch of Genitofemoral N. > Ilioinguinal N. towards spinal cord at level of L1 Efferent motor signal- Genital branch of Genitofemoral N. towards cremaster muscle to elevate the scrotum. Iliohypogastric Nerve (L1): Supplies skin above inguinal ligament Ilioinguinal Nerve (L1): Supplies skin of anterior scrotum and adjacent thigh Genitofemoral (L1, L2): Supplies skin below inguinal ligament, motor to cremaster muscle Note: Both the ilioinguinal nerve and genital branch of the genitofemoral nerve pass through the inguinal canal.", "cop": 2, "opa": "Femoral branch of genitofemoral nerve", "opb": "Genital branch of genitofemoral nerve", "opc": "Ilio-inguinal nerve", "opd": "Pudendal nerve", "subject_name": "Anatomy", "topic_name": "Nerve supply of Lower Limb", "id": "c34650dd-625b-4956-b251-9716616dd338", "choice_type": "single"} {"question": "Sweat gland near the lid margins", "exp": "Ans. is 'a' i.e., MollGlands of Moll (Moll's gland) are apocrine sweat glands just next to the eyelashes.Zeis glands are sebaceous glands near lid margins.Meibomian gland (tarsal glands) are specialized sebaceous gland at the rim of eyelids inside the tarsal plate.Krause's glands are accessory lacrimal glands underneath the eyelid.", "cop": 1, "opa": "Moll", "opb": "Zeis", "opc": "Meibomian", "opd": "Krause", "subject_name": "Anatomy", "topic_name": null, "id": "d5b797a4-ab9f-4b08-8174-1c40f1cff97a", "choice_type": "single"} {"question": "Light microscope characteristic feature of Apoptosis is", "exp": "Ref Robbins 9/e p14_15 ,26_27,9/e p53 The morphologic features characteristic of Apoptosis includes Cell srinkage: the cell is smaller in size having dense cytoplasm and the organelles are tightly packed. Chromatin condensation : This is the most characteristic feature of Apoptosis formation of cytoplasmic bleeds and apoptotic bodies", "cop": 4, "opa": "Intact cell membrane", "opb": "Eosinophilic cytoplasm", "opc": "Nuclear moulding", "opd": "Condensation of the nucleus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1399bc35-3903-4a8e-a2ce-39be53408438", "choice_type": "single"} {"question": "Foot drop is caused by damage to", "exp": "The common peroneal nerve is a component of the sciatic nerve. In the posterior thigh, it supplies the sho head of biceps femoris. It curves around neck of fibula deep to peroneus longus and divides into superficial and deep peroneal nerves. The superficial peroneal nerve innervates peroneus longus and peroneus brevis which are the eveors of foot and to the skin over the dorsal area of foot except the first webspace and lateral side of little toe. The deep peroneal nerve innervates all muscles of anterior compa which are the dorsiflexors of foot, extensor digitorum brevis, first two dorsal interossei muscles and skin between great and second toes. Hence, injury to common peroneal nerve will lead to weakness of dorsiflexion of foot or foot drop, loss of eversion, loss of extension of toes and sensory loss along anterior and lateral side of leg, dorsum of foot including medial side of great toe. Ref: Gray&;s Anatomy 41st edition PGno: 632", "cop": 1, "opa": "Common peroneal nerve", "opb": "Femoral nerve", "opc": "Tibial nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "11e615a4-d3f0-4dc0-ba61-5f507319da3f", "choice_type": "single"} {"question": "Posterior cord supplies", "exp": "The axillary nerve from the posterior cord supplies teres minor and deltoid muscle. Coracobrachialis is supplied by a musculocutaneous nerve from the lateral cord. Pectoralis minor is supplied by medial pectoral nerve arising from the medial cord and lateral pectoral nerves arising from lateral cord. The long head of biceps brachii is supplied by a musculocutaneous nerve from the lateral cord. BD Chaurasia 7th edition Page no: 57", "cop": 1, "opa": "Teres minor", "opb": "Pectoralis minor", "opc": "Coracobrachialis", "opd": "Long head of biceps", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "0c81fe12-7aff-4a4c-a367-7ae82631a156", "choice_type": "single"} {"question": "Urethral Crest is situated in", "exp": "Dissection of prostate showing prostatic urethra and urethral crest on posterior wall.In males, the urethral crest is known as the crista urethralis masculinae, or the crista phallica, and is a longitudinal fold on the posterior wall of the urethra extending from the uvula of the bladder through the prostatic urethra. ref - researchgate.net", "cop": 1, "opa": "Prostatic Urethra", "opb": "Membrnous Uretha", "opc": "Penile Urethra", "opd": "Bulbar Urethra", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "4e09b699-e173-4fd0-8e03-d89137f45c7e", "choice_type": "single"} {"question": "Teres minor muscle is supplied by", "exp": ".", "cop": 4, "opa": "Upper subscapular nerve", "opb": "Lower subscapular nerve", "opc": "Dorsal subscapular nerve", "opd": "Axillary nerve", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "bcc6271e-cf95-4216-86f5-ec22b6bb9801", "choice_type": "single"} {"question": "Vena comitans", "exp": "Vena comitans are the Veins accompanying aeries. Vena comitans is a vein that is usually paired, with both veins lying on the sides of an aery. They are found in close proximity to aeries so that the pulsations of the aery aid venous return.", "cop": 3, "opa": "Veins accompanying nerves", "opb": "Veins accompanying lymph vessels", "opc": "Veins accompanying aeries", "opd": "Veins accompanying veins", "subject_name": "Anatomy", "topic_name": "Introduction and gametogenesis.", "id": "8ec15d78-d43d-41df-968b-3df6e7aea897", "choice_type": "single"} {"question": "Most sensitive investigation of early bone infection", "exp": "Bone scan is very sensitive and is positive for changes appear on x-ray Refer Maheshwari 6th/e p 168", "cop": 3, "opa": "X-ray", "opb": "CT sCan", "opc": "Bone scan", "opd": "USG", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "920dbf8f-a1d1-440d-af64-7df67764a711", "choice_type": "single"} {"question": "Most common organs involved in the wagners granulomatosis are", "exp": "Refer robbins 9/e p511 Granulomatosis with polyangiitis (formerly called Wegener's) is a rare disease of unceain cause that can affect people of all ages. It is characterized by inflammation in various tissues, including blood vessels (vasculitis), but primarily pas of the respiratory tract and the kidneys. The areas most commonly affected by GPA include the sinuses, lungs, and kidneys, but any site can be affected", "cop": 2, "opa": "Skin and nose", "opb": "Lung and kidney", "opc": "Hea and kidney", "opd": "Kidney and nervous system", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "11fb03c6-1ece-41a3-8394-6a681c0e766b", "choice_type": "single"} {"question": "Broca's area is located in", "exp": null, "cop": 1, "opa": "Inferior frontal lobe", "opb": "Parietal lobe", "opc": "Superior temporal gyrus", "opd": "Angular gyrus", "subject_name": "Anatomy", "topic_name": null, "id": "e33301b5-c1c2-4a9f-985d-c59f37dfab20", "choice_type": "single"} {"question": "Commonest cause of cerebral infarction is", "exp": "Refer Robbins page no 1263 Infarction is tissue death (necrosis) due to inadequate blood supply to the affected area. It may be caused by aery blockages, rupture, mechanical compression, or vasoconstriction. The resulting lesion is referred to as an infarct (from the Latin infarctus, \"stuffed into\").", "cop": 1, "opa": "Aerial thrombosis", "opb": "Aeritis", "opc": "Venous thrombosis", "opd": "Embolism", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "8ec2a47b-9820-4e92-8514-dc0bf6a28b8f", "choice_type": "single"} {"question": "Nucleus pulposus is seen in", "exp": "(Intervertebral disc) (210-BDC-1 6th edition) (689-snell 9th edition)* The intervertebral disc is made up of a peripheral annulus fibrosus and a central nucleus pulposus* The physical characteristics permit them to serve as the shock absorbers* No discs are found between the first two cervical vertebrae or in the sacrum or coccyx* Laminae are connected by ligament flava* Spines are connected together by interspinous ligament and the ligamentous nuchae (represents the supra spinous ligament). The ligament gives origin to the splenius rhomboid and trapezius muscle* The intervertebral disces form about one quarter the length of the colomn* Discs are thickest in the lumber region* The most characteristic feature of the thoracic vertebrae is the body has costal facetsStructure of an intervertebral disc, (a) Superior view, (b) arrangement of laminae, and (c) vertical section", "cop": 1, "opa": "Intervertebral disc", "opb": "Medical meniscus", "opc": "Brain", "opd": "Vestibulo cochlear region", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "c9cce909-eb39-4c15-a231-dae0e3e62beb", "choice_type": "single"} {"question": "Inherited coagulation disorders are", "exp": "Ref Harrison 16/e p685 Primary (Genetic) Common (>1% of the Population) Factor V mutation (G1691A mutation; factor V Leiden) Prothrombin mutation (G20210A variant) 5,10-Methylene tetrahydrofolate reductase (homozygous C677T mutation) Increased levels of factor VIII, IX, or XI or fibrinogen Rare Antithrombin III deficiency Protein C deficiency Protein S deficiency Very Rare Fibrinolysis defects Homozygous homocystinuria (deficiency of cystathione b-synthetase)", "cop": 1, "opa": "Protein C deficiency", "opb": "Protein S deficiency", "opc": "Leiden factor mutation", "opd": "Lupus anticoagulant", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "04291adf-21c5-4298-b153-8de1214b35bc", "choice_type": "single"} {"question": "In Osteogenic sarcoma predominantly histology finding is DELETE", "exp": "Osteioid bone formation by tumor cells is Diagnostuc if OGS Refer Maheshwari 6th/e p 239", "cop": 2, "opa": "Giant cell", "opb": "Osteoid forming tumor cells", "opc": "Fibroblastic proliferation", "opd": "Chondtoblasts", "subject_name": "Anatomy", "topic_name": null, "id": "e8729790-c99c-40a4-9376-23877ef7313a", "choice_type": "single"} {"question": "Good collateral circulation occurs in", "exp": "Collateral circulation is the alternate circulation around a blocked aery or vein another path, such as nearby minor vessels. It may occur preexisting vascular redundancy (analogous to engineered redundancy), as in the circle of willis in the brain, or it may occur new branches formed between adjacent blood vessels (neovascularisation), as in the eye after a retinal embolism. Its formation may be provoked by pathological conditions such as high vascular resistance or ischemia . An example of the usefulness of collateral circulation is a systemic thromboembolism in cats. This is when a thrombotic embolus lodges above the external iliac aery (common iliac aery), blocking the external and internal iliac aeries and effectively shutting off all blood supply to the hind leg. Even though the main vessels to the leg are blocked, enough blood can get to the tissues in the leg the collateral circulation to keep them alive. Ref - sciencedirect.com", "cop": 1, "opa": "Skin", "opb": "Muscle", "opc": "Fascia", "opd": "Bone", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ca0c4c83-9a07-4237-8978-d5cf1eaf4098", "choice_type": "single"} {"question": "Minimum dose of estrogen in combined OCP's", "exp": ".", "cop": 1, "opa": "20mcg", "opb": "30cg", "opc": "35mcg", "opd": "50mcg", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "bf541c7a-d272-4d68-90ca-288371d76979", "choice_type": "single"} {"question": "Simple squamous epithelium is seen in", "exp": "Squamous epithelium lines theinside of the hea ,where it is called endothelium INDERBIR SINGH&;S TEXT BOOK OF HUMAN HISTOLOGY-REFERENCE page no:41", "cop": 1, "opa": "Blood vessels", "opb": "Thyroid follicle", "opc": "Esophagus", "opd": "Hard palate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b39377c2-e8a7-47ed-b462-eba630e740fb", "choice_type": "single"} {"question": "Wound contraction is mediated by", "exp": "ref, Robbins 9/e p105 The chief physiological function of myofibroblasts in mammalian tissues has been in wound healing and specifically in contraction of the wound. Typically there are four overlapping phases of wound healing: Haemostasis, inflammation, proliferation, and remodelling", "cop": 2, "opa": "Epithelial cells", "opb": "Myofibroblasts", "opc": "Collagen", "opd": "Elastin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f26de4ed-7397-4bb7-9f07-1f8348602aca", "choice_type": "single"} {"question": "Opsonins are", "exp": "ref Robbins 8/e p51-53 ;7/e p59,9/e p78", "cop": 3, "opa": "C3a", "opb": "IgM", "opc": "Carbohydrates binding protein", "opd": "Selectins", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "214ead16-3e33-4dea-9afd-2915a6368f06", "choice_type": "single"} {"question": "The substance used in OCG is", "exp": "Iopanoic acid is used in oral cholecystography Biligraffin is used in IV cholangiography Ref: Sabiston 20th edition Pgno :1487", "cop": 1, "opa": "Iopanoic acid", "opb": "Sodium diatrozite", "opc": "Meglumine iodothalamate", "opd": "Biligraffin", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b4d24c74-0839-4a0c-a90a-9edd6bf0525c", "choice_type": "single"} {"question": "Central sulcus is an example of", "exp": "Limiting sulcus develops along the plane of the coical areas, which differ in the function they primarily subserve. Central sulcus (of Rolando) forms the boundary between the motor area of cerebral coex in front and sensory area behind. Calcarine sulcus is also a limiting sulcus. Axial sulci develop along the long axis of rapidly growing homogenous areas. Operculated sulcus is similar to limiting sulcus in that it separates functionally different areas but transition occurs in the lip and not on the floor. Complete sulcus is deep enough to produce an elevation in the wall of ventricle.(Ref: Vishram Singh textbook of clinical neuroanatomy, second edition pg- 142)", "cop": 1, "opa": "Limiting sulcus", "opb": "Axial sulcus", "opc": "Operculated sulcus", "opd": "Complete sulcus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "93ec55ea-79e4-4552-b2a3-123030d4cf30", "choice_type": "single"} {"question": "Lining Epithelium of respiratory bronchiole is", "exp": "The Bronchioles are subdivided into terminal bronchioles which fuher divides to form respiratory bronchioles. Respiratory bronchiole is the smallest bronchiole & it is lined with Simple Cuboidal Cells.", "cop": 4, "opa": "Pseudo Stratified Columnar with Goblet Cells", "opb": "Pseudo Stratified Columnar", "opc": "Columnar", "opd": "Cuboidal", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "387f6a17-742e-4bdb-ac27-fca1cf972309", "choice_type": "single"} {"question": "Medial boundary of Femoral Ring", "exp": "Femoral Ring:It is represented by a horizontal line 1.25 cm long over the inguinal ligament, 1.25 cm medial to the midinguinal pointIt is bounded anteriorly by the inguinal ligament, posteriorly by the pectineus and its covering fascia, medially by the concave margin of the lacunar ligament, and laterally by the septum separating it from the femoral vein. The inferior epigastric vessels are closely related to the junction of the anterior and lateral walls of the ring. The femoral ring is closed by a condensation of extraperitoneal connective tissue called the femoral septum. The femoral canal contains a lymph node of Cloquet or of Rosenmuller, lymphatics, and a small amount of areolar tissue. The lymph node drains the glans penis in males and the clitoris in femalesReference: Chaurasia Volume II; 7th edition; Page no: 51", "cop": 2, "opa": "Inguinal Ligament", "opb": "Lacunar Ligament", "opc": "Pectineus", "opd": "Femoral Vein", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e3e46bc6-fd69-40df-971f-0720262490a1", "choice_type": "single"} {"question": "Duct of Rivinus is associated with", "exp": null, "cop": 3, "opa": "Parotid gland", "opb": "Submandibular gland", "opc": "Sublingual gland", "opd": "Minor salivary gland", "subject_name": "Anatomy", "topic_name": null, "id": "9e15b747-8896-467c-8f5b-ab3035b9617f", "choice_type": "single"} {"question": "In cholangiography CBD stone appears as", "exp": "Mr cholangiography : provides excellent anatomic detail, with sensitivity and specificity of 95 %and 98 %respectively for CBD stones Typical meniscus sign is seen when the CBD stone is wedged at the level of the papilla Ref: Sutton 6th edition Pgno : 971", "cop": 1, "opa": "Meniscus sign", "opb": "Cutoff sign", "opc": "Slight flow of dye from the sides", "opd": "Ability to absorb water", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "38e9ea6f-df33-4480-8c1c-237c1cfb8595", "choice_type": "single"} {"question": "Snowfield vision is characteristic of", "exp": "Methyl alcohol poisoning Visual disturbances may be the early symptoms. The person may develop photophobia, blurring of vision (Snowfield vision), central and peripheral scotoma, dilated pupils and sudden failure of vision. Blindness is caused by formic acid accumulation in the retinal cells and optic disc show degenerative changes and edema on fundoscopy. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 444", "cop": 2, "opa": "Ethyl alcohol poisoning", "opb": "Methyl alcohol poisoning", "opc": "Ethylene glycol poisoning", "opd": "Isopropanol poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "ff8b881d-53e2-4896-a5b8-5dc8b9a841e3", "choice_type": "single"} {"question": "Impotant adverse effect of nesiritide is", "exp": "Ref-Goodman and Gillman 12/e p696 Commonly repoed side effects of nesiritide include: asymptomatic hypotension, hypotension, symptomatic hypotension, and increased serum creatinine.", "cop": 2, "opa": "Dysgusea", "opb": "Hypotension", "opc": "Cough", "opd": "Angiodema", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "64ef734c-83df-41e0-a98c-24918fa769df", "choice_type": "single"} {"question": "patient has decreased weight, need for thinness, the diagnosis is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "refeeding syndrome", "opb": "anorexia nervosa", "opc": "metabolic syndrome", "opd": "bulimia nervosa", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "1abd9ca7-7e2d-4c0e-9232-2324a9d45711", "choice_type": "single"} {"question": "Tennis Racquet cells are seen in", "exp": "Refer Robbins page no 1001 Embryonal RMS, primarily a lesion of the head and neck region, especially the orbit, is a type of tumor usually occurs in youngsters and at the age of 10 years. This tumor is characterized by a mixture of round cells and cells with an eccentric nucleus, so called \"tadpole\" or tennis \"racquet\".\"\"", "cop": 1, "opa": "Rhabdomyosarcoma", "opb": "Rhabdomyoma", "opc": "histocytosis", "opd": "Eosinophilic granuloma", "subject_name": "Anatomy", "topic_name": null, "id": "52e1251f-74b5-4a19-b9b6-1ab08c4a7bd1", "choice_type": "single"} {"question": "Gasless abdomen in xRay is a sign of", "exp": "Radiological appearance of Acute pancreatitis Renal halo sign Gasless abdomen. Ground glass appearance Colon cut off sign Sentinel loop Ref: Sabiston 20th edition Pgno : 1527", "cop": 1, "opa": "Acute pancreatitis", "opb": "Necrotizing enterocolitis", "opc": "Ulcerative colitis", "opd": "Intussusception", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1586d3ea-47b2-4c0b-aaa0-5e74643688c1", "choice_type": "single"} {"question": "Acinar cells of the Exocrine Pancreas secrete", "exp": "Several Proteases are synthesized by Pancreatic Acinar Cells and are delivered the Pancreatic Duct to the Duodenum", "cop": 4, "opa": "Glucagon", "opb": "Lysozyme", "opc": "Insulin.", "opd": "Proteases", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "9fc17f57-9666-4251-82bb-feae9176461b", "choice_type": "single"} {"question": "Styloid process is derived from", "exp": "The styloid process,the stylohyoid ligament and muscle are derived from the second branchial arch. REF.BDC VOL.3,Fifth Edition,", "cop": 2, "opa": "First arch", "opb": "Second arch", "opc": "Third arch", "opd": "Fouh arch", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "505a2b54-a2b1-456f-b8c4-21a73af773ba", "choice_type": "single"} {"question": "Medial border of triangle of auscultation is", "exp": "Triangle Of Auscultation It is a small triangular interval interval bounded medially by the lateral border of the trapezius, laterally by the medial border of the scapula,and inferiorly by the upper border of the latissimus dorsi.The floor of the triangle is formed by the seventh rib,sixth and seventh intercostal spaces,and the rhomboideus major. Ref.B D Chaurasia's human anatomy vol.1.", "cop": 2, "opa": "Trapezius", "opb": "Scapula", "opc": "Lattismus dorsi", "opd": "Rhomboids major", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "3fa1f056-37ea-4733-8d18-5dd42d012164", "choice_type": "single"} {"question": "The most common site for Amoebiasis", "exp": "Refer Robbins page no Pg p 795 Amoebiasis is seen most definitely in the cecum and ascending colon", "cop": 3, "opa": "Sigmoid colon", "opb": "Transverse colon", "opc": "Cecum", "opd": "Colon", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "be4ff9a0-457a-4a8c-801e-5d0fb951b254", "choice_type": "single"} {"question": "Grynfeltt triangle not bounded by", "exp": "Lumbar hernias- Hernias through the superior lumbar triangle (Grynfeltt triangle) are more common and bounded by the 12th rib, paraspinal muscles, and internal oblique muscle. Inferior Lumbar / Petit triangle- bounded by the iliac crest, latissimus dorsi muscle, and external oblique muscle.", "cop": 4, "opa": "12th rib", "opb": "Paraspinal muscles", "opc": "Internal oblique muscle", "opd": "External oblique muscle", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ac36165a-ad17-4eac-b102-1db616bb0061", "choice_type": "single"} {"question": "Almost exclusively urinary bladder is lined by", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:320", "cop": 3, "opa": "Squamous epithelium", "opb": "Columnar epithelium", "opc": "Transitional epithelium", "opd": "Cuboidal epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d80e8723-a8ba-448f-aec2-d8cd095e7750", "choice_type": "single"} {"question": "Increased risk of cancer is seen in", "exp": "Ref Robbins 8/e p276; 9/e p279 Ceain non neoplastic disorders _ the chronic atrophic gastric of pernicious Anemia, solar keratosis of skin, chronic ulcerative colitis and leukoplakia of the oral cavity, vulva and penis, have such a well defined association with cancer that they have been termed precancerous condition", "cop": 3, "opa": "Fibroadenoma of breast", "opb": "Bronchial asthma", "opc": "Chronic ulcerative colitis", "opd": "Leiomyoma of the uterus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6edfbd0f-11f3-4545-a6fd-06d8bd77dc26", "choice_type": "single"} {"question": "Special visceral efferent DOESN'T include", "exp": "Dorsal nucleus of tenth cranial nerve belongs to GVE (general visceral efferent) neural column It supplies the three effectors under autonomic system: cardiac muscles, smooth muscles and glands. Special visceral efferent (SVE) neural column supplies skeletal muscles developing in pharyngeal arches. Ref: Gray's 39e/p-227", "cop": 3, "opa": "Motor nucleus of fifth cranial nerve", "opb": "Motor nucleus of seventh cranial nerve", "opc": "Dorsal nucleus of tenth cranial nerve", "opd": "Nucleus ambiguous", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "3a0993cc-ce65-45f4-a4c2-0483d3678fa6", "choice_type": "single"} {"question": "Most impoant clinical feature of primary biliary cirrhosis", "exp": "Primary biliary cirrhosis Believed to be an autoimmune etiology, leading to progressive destruction of intrahepatic bile ducts More common in females Associated with autoimmune disorders (CREST, Sicca syndrome, Autoimmune thyroiditis, Renal tubular acidosis) Clinical features Most patients are asymptomatic, pruritus the commonest and earliest symptom. Pruritus precedes jaundice in PBC, Pruritus is most bothersome in evening Jaundice, fatigue, melanosis (gradual darkening of exposed areas of skin), deficiency of aft soluble vitamins due to malabsorption Xanthomas and xanthelesmas due to protracted elevation of serum lipids Ref: Sabiston 20th edition Pgno : 639", "cop": 1, "opa": "Generalised pruritus", "opb": "Jaundice", "opc": "Clubbing", "opd": "Hematemesis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "bdcce9f5-e780-44aa-84c6-9f81e2b11c66", "choice_type": "single"} {"question": "Major neurotransmitter released at end organ effectors of the sympathetic division of the autonomic nervous system is", "exp": "Neurotransmitter secreted it in organ effectors of sympathetic system is mostly nor-adrenaline (except in sweat glands and haur follicle, where it Is acettacetylch) where as it is acetylcholine at parasympathetic system Ref-KDT 6/e p116", "cop": 2, "opa": "Adrenaline", "opb": "Noradrenaline", "opc": "Dopamine", "opd": "Acetylcholine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "425f8a8c-0ffa-4768-a9a7-e9cbd124d444", "choice_type": "single"} {"question": "IgE receptors are present on", "exp": "Ref Robbins 9/e p201 Type 1 hypersensitivity is a rapid immunological reaction occuring in a previously sensitized individual that is triggered by the binding of an antigen to IgE antibody on the surface of mast cells", "cop": 1, "opa": "Mast cells", "opb": "NK cells", "opc": "B cells", "opd": "Histiocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "178f2a2f-ecac-46c2-86d7-6e2f852c1032", "choice_type": "single"} {"question": "Muscle(s) supplied by facial nerve is/are", "exp": "Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition. The nerve to the stapedius, branch of facial nerve arises opposite the pyramid of the middle ear, and supplies the stapedius muscle.", "cop": 1, "opa": "Stapedius", "opb": "Anterior diagastric", "opc": "Risorius", "opd": "Stylohoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "192b7c7f-2aa7-4129-9752-03146b09c0e4", "choice_type": "single"} {"question": "Biopsy of the exposed surface of the palatine tonsil reveals the following type of tissue", "exp": "The palatine tonsil is situated at the oropharyngeal isthmus. Its oral aspect is covered with stratified squamous nonkeratinized epithelium, which dips into the underlying tissue to form the crypts. The lymphocytes lie on the sides of the crypts in the form of nodules. The tonsil has two surfaces medial and lateral. The medial surface is covered by stratified squamous epithelium continuous with that of the mouth. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 4, "opa": "Simple columnar epithelium", "opb": "Pseudostratified columnar ciliated epithelium", "opc": "Simple squamous epithelium", "opd": "Stratified squamous epithelium", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "808901a2-11fa-4473-90bd-3d391742a92f", "choice_type": "single"} {"question": "Hyoid bone is a derivative of", "exp": null, "cop": 3, "opa": "First pharyngeal arch", "opb": "First and second pharyngeal arches", "opc": "Second and third pharyngeal arches", "opd": "Fourth pharyngeal arch", "subject_name": "Anatomy", "topic_name": null, "id": "0eaa7cc5-5537-4d3e-9114-9147cc4275e8", "choice_type": "single"} {"question": "Successful antibiotic penetration of a burn eschar can be achieved with", "exp": "Mafenide acetate is the antibiotic agent that penetrates burn eschar to reach the interface with patient's ble tissue This agent has the Disadvantage that it is quite painful on any paial thickness areas and it is carbonic anhydrase inhibitor that interferes with renal buffering mechanism Metabolic acidosis can occur Ref: schwaz's principle of surgery 10th edition Pg no: 232", "cop": 1, "opa": "Mafenide Acetate", "opb": "Neomycin", "opc": "Silver nitrate", "opd": "Silver sulfadiazine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "00749b8f-4edd-4444-9b64-5c6776bc7ec6", "choice_type": "single"} {"question": "Most common aery involved in pancreatic pseudoaneurysm", "exp": "Aeries involved in pseudoaneurysm associated with pancreatic pseudocyst Splenic Aery (30-50%):Most common Gastroduodenal aery : (10-15%) Inferior and superior pancreaticoduodenal aery (10%) Ref: Maingot 11th edition Pgno :977", "cop": 4, "opa": "Gastroduodenal aery", "opb": "Inferior pancreaticoduodenal aery", "opc": "Gastric aery", "opd": "Splenic aery", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3c07cd21-ee56-4020-ada5-75d8372b14af", "choice_type": "single"} {"question": "Primordial germ cell is derived from", "exp": "Primordial germ cell is derived from epiblast, earlier they were believed to arise from endoderm of yolk sac They became evident at the distal end of primitive streak by the 2nd week of intrauterine life, these cells migratory and reach the endodermal wall of yolk sac, they reach the gonad by the 5th week Gray's 39e/p-210-220", "cop": 3, "opa": "Ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Mesodermal sinus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d479aa36-490d-4c57-afca-b9f0b09f5c75", "choice_type": "single"} {"question": "mood stablizer used in the management of temporal lobe epilepsy", "exp": "Carbamazepine - USES - TRIGEMINAL NEURALGIA - TEMPORAL LOBE EPILEPSY - SECOND LINE MOOD STABILIZER Ref. Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no.935", "cop": 1, "opa": "carbamezepine", "opb": "valproate", "opc": "lamotrigine", "opd": "lithium", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "53af0b75-28dd-499d-8921-1a113c131da3", "choice_type": "single"} {"question": "Sensory supply to external auditory meatus is by /\nsensory nerve supply to external ear is by", "exp": null, "cop": 3, "opa": "Facial nerve", "opb": "Vestibulococchlear nerve", "opc": "Trigeminal nerve", "opd": "Glossopharyngeal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "2e08d41e-966f-464b-b7bf-a18fd0d678cf", "choice_type": "single"} {"question": "Mouth opening is due to action of", "exp": null, "cop": 1, "opa": "Lateral pterygoid", "opb": "Medial pterygoid", "opc": "Temporalis", "opd": "Masseter", "subject_name": "Anatomy", "topic_name": null, "id": "91511594-3f10-4d2e-9c69-ed1853a8346e", "choice_type": "single"} {"question": "The second stage of deglutition is characterized by", "exp": null, "cop": 1, "opa": "Elevation of larynx", "opb": "Momentary apnoea", "opc": "Peristalsis of Pharyngo esophageal sphincter", "opd": "Relaxation of pharyngeal constrictors", "subject_name": "Anatomy", "topic_name": null, "id": "826333f7-d29d-40ba-a759-2d2c7b456f06", "choice_type": "single"} {"question": "Agent of first choice in an acute attack of Prinzmetal's angina is", "exp": "Ref Harrison 19 th ed pg 1598 Prinzmetal's Variant Angina Nitrates and calcium channel blockers are the main therapeutic agents. Aspirin may actually increase the severity of ischemic episodes, possibly as a result of the sensitivity of coronary tone to modest changes in the synthesis of prostacyclin.", "cop": 2, "opa": "Diltiazem", "opb": "Nitrates", "opc": "Propranolol", "opd": "Verapamil", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c2aefceb-322a-4382-ad8d-5a39a389b39f", "choice_type": "single"} {"question": "Nerve supply of Glans penis is", "exp": "Innervation of penis : nerves deriving from S2-S4. Sensory & sympathetic innervation: provided by the dorsal nerve of penis (terminal branch of pudendal nerve), which runs lateral to dorsal aery of penis. It Supplies both skin and glans. The sensory endings are more numerous on the glans). Ilioinguinal nerve branches supply skin at the root. Parasympathetic innervation: provided by cavernous nerves that innervate the helicine aeries in the corpora cavernosa (that is why erection is parasympathetically stimulated). Ref - medscape.com", "cop": 4, "opa": "Genital branch of genito-femoral nerve", "opb": "Ilio-inguinal nerve", "opc": "Ilio-hypogastric nerve", "opd": "Pudendal nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "299a77da-7720-4505-b353-42de9d8a764d", "choice_type": "single"} {"question": "seizure is a side effect of", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients * Side effects * Agranulocytosis * Myocarditis * Seizure * Constipation * Weight gain * Metabolic syndrome Sialorrhea Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no, 935", "cop": 1, "opa": "clozapine", "opb": "olanzapine", "opc": "aripiprazole", "opd": "amisulpride", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "bf8d61e3-3f56-4b25-bb92-f6dc269e6442", "choice_type": "single"} {"question": "Plunging goitre is", "exp": "Refer Robbins page no 1092 Multinodular goiters are multilobulated, asymmetrically enlarged glands that can reach weights of more than 2000 gm. The pattern of enlargement is quite unpredictable and may involve one lobe far more than the other, producing lateral pressure on midline structures, such as the trachea and esophagus. In other instances the goiter grows behind the sternum and clavicles to produce the so-called intrathoracic or plunging goiter. Occasionally, most of it is hidden behind the trachea and esophagus; in other instances one nodule may stand out, impaing the clinical appearance of a solitary nodule. On cut section, irregular nodules containing variable amounts of brown, gelatinous colloid are present (Fig. 24-15A). Older lesions have areas of hemorrhage, fibrosis, calcification, and cystic change. The microscopic appearance includes colloid-rich follicles lined by flattened, inactive epithelium and areas of follicular hyper- plasia, accompanied by degenerative changes related to phys- ical stress. In contrast to follicular neoplasms, a prominent capsule between the hyperplastic nodules and residual com- pressed thyroid parenchyma is not present", "cop": 3, "opa": "Solitary nodule", "opb": "Colloid goitre", "opc": "Retro sternal goitre", "opd": "Medullary carcinoma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "d7f7b755-128f-4785-9212-b2cc353ba7a2", "choice_type": "single"} {"question": "The surface marking of the arch of aoa is as follows", "exp": "ARCH OF AOA It lies behind the lower half of the manubrium sterni.Its upper convex border is marked by a line which begins at the right end of the sternal angle,arches upwards and to the left through the centre of the manubrium and ends at the sternal end of the left second costal cailage.Note that the beginning and end of the arches are at the same level.When marked on the surface as descried above the arch looks much smaller than it actually is because of foreshoening. BD CHAURASIA 'S HUMAN ANATOMY VOL.1,FIFTH EDITION", "cop": 1, "opa": "Behind the manubrium sterni", "opb": "2nd intercostal space", "opc": "3rd intercostal space", "opd": "Left 2nd costal cailage", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "60fb0cdc-63d4-49fe-892a-a193bb5982e5", "choice_type": "single"} {"question": "Thorium induced tumor", "exp": "Refer Robbins page no Pg 875", "cop": 1, "opa": "Angiosarcoma of liver", "opb": "Renal cell carcinoma", "opc": "Lymphoma", "opd": "Astrocytoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8b3716c7-9e73-4ad6-911a-c218aa49cba7", "choice_type": "single"} {"question": "Mammography was performed in 45 year old female for screening of breast cancer. The finding is suggestive of", "exp": "Mammography Soft tissue radiographs are taken by placing the breast in direct contact with ultrasensitive film and exposing it to low-voltage, high-amperage x-rays. The dose of radiation is approximately 0.1 cGy and, therefore, mammography is a very safe investigation. The sensitivity of this investigation increases with age as the breast becomes less dense. In total, 5% of breast cancers are missed by population-based mammographic screening programmes; even in retrospect, such carcinomas are not apparent. Thus, a normal mammogram does not exclude the presence of carcinoma. Digital mammography is being introduced, which allows manipulation of the images and computer-aided diagnosis. Tomo-mammography is also being assessed as a more sensitive diagnostic modality. Ultrasound Ref: Sabiston 20th edition Pgno : 861", "cop": 2, "opa": "Benign lesion", "opb": "Malignant lesion", "opc": "Indeterminate", "opd": "No opinion can be given", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "751b17ee-126c-4a03-ae37-7e5d09e7b367", "choice_type": "single"} {"question": "Resting pressure in the anal canal is because of", "exp": "Anal manometry has been used in the study of patients who have fecal incontinence as an attempt to quantify anal sphincter function. Typical basic parameters are resting pressure and squeeze pressure. Resting pressure denotes resting tonicity and thus is used as an index parameter for internal anal sphincter which is in charge of that tonicity, while squeeze pressure denotes the strength of voluntary contraction and is used for contractility of external anal sphincter. But resting pressure is usually regarded more reliable as an index of continence function judging from physical propeies during metric procedure because squeeze pressure depends more on patient's subjective effo with resultant more variation. Resting pressure has, however, a restriction that it represents cross sectional status of the anal canal without taking into consideration its three dimensional structure. Resting pressure gradient (RPG) of the anal canal is devised as one of the advanced parameters to make up for such a restriction. The RPG is given by the ratio of pressure difference between maximum resting pressure and basal resting pressure to interval distance between their levels. Therefore, it can be said that it has 2 components as factors of determination, which are pressure and length factor, respectively. Ref - pubmed.com {Reference: BDC 6E chapter 13.}", "cop": 2, "opa": "Deltoid ligament", "opb": "Spring ligament", "opc": "Sho plantar ligament", "opd": "Long plantar ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d078b80e-2fd4-491b-b629-d2c32a84eaf0", "choice_type": "single"} {"question": "Ducts of bellini are found in", "exp": "The Uriniferous Tubules - From a functional point of view the kidney may be regarded as a collection of numerous uriniferous tubules that are specialised for the excretion of urine. Each uriniferous tubule consists of an excretory pa called the nephron, and of a collecting tubule. The collecting tubules draining different nephrons join to form larger tubules called the papillary ducts (of Bellini), each of which opens into a minor calyx at the apex of a renal papilla. Each kidney contains one to two million nephrons. Urinary tubules are held together by scanty connective tissue. Blood vessels, lymphatics and nerves lie in this connective tissue. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no., 304.", "cop": 3, "opa": "Pancreas", "opb": "Submandibular salivary gland", "opc": "Kidney", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bf1f6944-f150-42e1-aa8b-987e409daeb4", "choice_type": "single"} {"question": "Spinal cord in children ends at the lower border of", "exp": "Veebral level and spinal cordSpinal cord in adults ends at L1, L2Spinal cord in children ends at L3Highest point of iliac crest is at L4", "cop": 3, "opa": "L1", "opb": "L2", "opc": "L3", "opd": "L4", "subject_name": "Anatomy", "topic_name": null, "id": "aa5add13-8d4f-4438-b776-abecdeac524c", "choice_type": "single"} {"question": "\"Nucleus ambiguus\" is present at", "exp": "The nucleus ambiguus is found in the lateral medulla; it gives rise to the SVE (Special visceral efferent fibers ) components of cranial nerves IX and X. fig:- crossection at the level of medulla(upper pa)", "cop": 4, "opa": "Base of pons", "opb": "Midbrain, at level of superior colliculus", "opc": "Midbrain, at level of inferior colliculus", "opd": "Lateral medulla", "subject_name": "Anatomy", "topic_name": "Brainstem, cerebellum and ventricles", "id": "acf53208-474f-44bd-b5b0-451c3845697e", "choice_type": "single"} {"question": "Pharmacological stressor used in PET scan to detect cardiac function is", "exp": "Instead of treadmill test,dobutamine can be used.", "cop": 2, "opa": "Dopamine", "opb": "Dobutamine", "opc": "Droxidopa", "opd": "Nor adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e83a7d26-cb81-42fc-8cd7-b4f943977d2e", "choice_type": "single"} {"question": "The muscles attached to perineal body are A/E", "exp": "Ten muscles of the perineum converge and interlace in the perineal body - a) Two unpaired : (i) External anal sphincter, (ii) Fibres of longitudinal muscle coat of anal canal. b) Four paired:- (i) Bulbospongiosus, (ii) Superficial transverse perenei, (iii) Deep transversus perenei, (iv) levator ani, In females, sphincter urethrovaginalis is also attached here. Ref: Gray&;s anatomy text book of anatomy BD chaurasia 21st Ed.", "cop": 1, "opa": "Ischiocavernosum", "opb": "Bulbospongiosm", "opc": "Superficial transverse perinea", "opd": "Deep transverse perinea", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b678cb1e-fa6a-484c-abb0-bc54a655418a", "choice_type": "single"} {"question": "Hyperosmolarcoma are caused by the following excep t by", "exp": "though the concentration of proteins is large they only contribute 2mosm/lbecause of their very high molecular weights", "cop": 3, "opa": "Hyperglycemia", "opb": "Uremia", "opc": "Increased concentration of plasma proteins", "opd": "Increase in plasma sodium concentration", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "07a510c1-78ea-4ad2-8982-eaabe402e308", "choice_type": "single"} {"question": "Cricothyroid is supplied by", "exp": null, "cop": 2, "opa": "Recurrent laryngeal", "opb": "External laryngeal", "opc": "Internal laryngeal", "opd": "Superior laryngeal", "subject_name": "Anatomy", "topic_name": null, "id": "9d0f6e1e-d69c-4c9c-9f95-3e793e69458d", "choice_type": "single"} {"question": "Predominant blood supply to the Supra duodenal bile duct is derived from", "exp": "Vascular supply of biliary tract The Supra duodenal and infrahilar bile duct are Predominantly supplied by two axial vessels that run in a 3- and 9-'o clock position These vessels are derived from the superior pancreaticoduodenal, right hepatic, cystic, gastroduodenal and retro duodenal aeries It has been estimated that only 2% of the aerial supply to this poion of the bile duct is segmental and arises directly off of the proper hepatic aery The bile duct and its bifurcation in the hilum derive their aerial supply from a rich network of multiple small branches from surrounding vessels Retro pancreatic bile duct derives its aerial supply from the retroduoden aery Venous drainage of the bile duct parallels the aerial supply and drains into the poal venous system The venous drainage of the gallbladder empties into the veins that drain the bile duct and doesnot flow directly to the poal vein Ref: Sabiston 20th edition Pgno : 1482-1483", "cop": 1, "opa": "Vessels that run upward along the bile duct from the duodenal end of the duct such as the retro duodenal and gastroduodenal aeries", "opb": "Vessels that run downward along the bile duct from the hepatic end of the duct such as the right hepatic aery", "opc": "Vessels that arise from the hepatic aery proper run up along the CBD and supplies it with twigs in Non-axial distribution", "opd": "Vessels that arise from the cystic aery", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "120ff088-c008-4dc8-8294-3f2d8f58dbdf", "choice_type": "single"} {"question": "Most sensitive indicator of intravascular volume depletion in child is", "exp": "Capillary refill is a simple test that assesses how quickly blood returns to the skin after pressure is applied. It is carried out by applying pressure to the pink pa of the nail bed of the thumb or big toe in a child and over the sternum or forehead in a young infant for 3 seconds. The capillary refill time is the time from release of pressure to complete return of the pink color. It should be less than 3 seconds. If it is more than 3 seconds the child may be in shock. Lift the limb slightly above hea level to assess aeriolar capillary refill and not venous stasis. This sign is reliable except when the room temperature is low, as the cold environment can cause a delayed capillary refill. In such a situation check the pulses and decide about shock", "cop": 1, "opa": "Hea rate", "opb": "Cardiac output", "opc": "Blood pressure", "opd": "Stroke volume", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94f3c959-a095-4afe-907a-20f7e24d3b6f", "choice_type": "single"} {"question": "Toynbee's muscle is", "exp": "Tensor tympani is called as Toynbee muscle origin, the cailaginous pa of the pharyngotympanic (auditory) tube and the walls of its hemicanal just above the bony poion of the pharyngotympanic tube; inseion, handle of malleus; action, draws the handle of the malleus medially tensing the tympanic membrane to protect it from excessive vibration by loud sounds. nerve supply, branches of trigeminal through the otic ganglion Ref - Pubmed.com", "cop": 1, "opa": "Tensor tympani", "opb": "Stapedius", "opc": "Levator ani", "opd": "Scalenus minimus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "46243a79-d51b-48f2-b127-b76c2e1e37f5", "choice_type": "single"} {"question": "Musculocutaneous nerve is a branch of", "exp": "REF.BDC VOL.1,FIFTH EDITION.pg.88 The musculocutaneous nerve is the main nerve of the front of the arm and continues below the elbow as the lateral cutaneous nerve of the forearm.It is a branch of the lateral cord of the brachial plexus,arising at the lower border of the pectoralis minor in the axilla.", "cop": 2, "opa": "Root of brachial plexus", "opb": "Lateral cord of brachial plexus", "opc": "Medial cord of brachial plexus", "opd": "Posterior cord of brachial plexus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "dbfe1363-1c5a-4a69-9a0d-fe4ed7f5da05", "choice_type": "single"} {"question": "Most common nerve involvement in fracture surgical neck humerus", "exp": "Refer Maheshwari 6th/e p 92 Axillary nerve is paicularly vulnerable, both from the injury and from surgery", "cop": 1, "opa": "Axillary nerve", "opb": "Radial nerve", "opc": "Ulnar nerve", "opd": "Median nerve", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ad7e940-bf6a-47d7-8b68-f8e706d9b4b9", "choice_type": "single"} {"question": "Superior pancreaticoduodenal aery is a branch of", "exp": "The superior pancreaticoduodenal aery is an aery that supplies blood to the duodenum and pancreas. It is a branch of the gastroduodenal aery, which most commonly arises from the common hepatic aery of the celiac trunk, although there are numerous variations of the origin of the gastroduodenal aery. The pancreaticoduodenal aery divides into two branches as it descends, an anterior and posterior branch", "cop": 3, "opa": "Hepatic aery", "opb": "Splenic aery", "opc": "Gastroduodenal aery", "opd": "Inferior mesenteric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "7bf5390b-d5b8-469e-bc69-fc7e5698226b", "choice_type": "single"} {"question": "CD 99 is for", "exp": "Refer Harrison 17th/613", "cop": 1, "opa": "Ewings sarcoma", "opb": "SLL", "opc": "Dermatofibroma protuberans", "opd": "Malignant Histiocytic fibroma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "ec1d077d-b055-4010-bea6-04f3a6692b66", "choice_type": "single"} {"question": "Wharton's duct drains", "exp": "(A) Submandibular gland # Submandibular gland: It is irregular in shape & about the size of a walnut.> It consists of a larger superficial and a smaller deep part, continuous with each other around the posterior border of mylohyoid.> It is seromucous (but predominantly serous) gland.# Wharton's duct emerges from the medial surface of this part of the gland behind the posterior border of mylohyoid.> It traversed the deep part of the gland passes at first up and slightly back for 0.5 mm, and then forwards between mylohyoid and hyoglossus.> It next passes between the sublingual gland and genioglossus to open in the floor of the mouth on the summit of the sublingual papilla at the side of the frenulum of the tongue. It lies between the lingual and hypoglossal nerves on hypoglossus, but, at the anterior border of the muscle, it is crossed laterally by the lingual nerve, terminal branches of which ascend on its medial side.> As the duct traverses the deep part of the gland it receives small tributaries draining this part of the gland like the parotid gland, the duct system of the submandibular gland can be visualized by sialography.", "cop": 1, "opa": "Submandibular gland", "opb": "Sublingual gland", "opc": "Parotid gland", "opd": "Lacrimal gland", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "06c8472c-cefa-4f07-a7c1-8870d3e103e0", "choice_type": "single"} {"question": "Bursa communicating with the shoulder joint space is", "exp": "Infraspinatus bursa may communicate with the shoulder joint. Subacromial bursa separates the acromion process and the coracoacromial ligaments from supraspinatus tendon and permit smooth motion. B D Chaurasia 7th edition Page no: 148", "cop": 2, "opa": "Infraspinatous bursa", "opb": "Subscapular bursa", "opc": "Subcoracoid bursa", "opd": "Subacromian bursa", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e2676d6a-89bb-4148-aeee-4193855f89c6", "choice_type": "single"} {"question": "Node of Rouviere is", "exp": "Ref: Various articles & internet sources\nNode of Rouviere is the most superior of the lateral group of the retropharyngeal lymph nodes. It is found at the base of the skull. They represent one of the first echelon lymphnodes typically involved in nasopharyngeal carcinoma (NPC).", "cop": 1, "opa": "Retropharyngeal", "opb": "Pharyngeal", "opc": "Nasopharyngeal", "opd": "Retromolar trigone", "subject_name": "Anatomy", "topic_name": null, "id": "325b4a30-8749-4d45-a26b-0c3d2207eb44", "choice_type": "single"} {"question": "Lymph from glans penis drain into", "exp": "Lymphatics from the glans drain into the deep inguinal nodes also called gland of Cloquet. Lymphatics from the rest of the penis drain into the superficial inguinal lymph nodes.Ref: Vishram Singh; Volume II; 2nd edition; Page no: 464", "cop": 3, "opa": "External iliac lymph nodes", "opb": "Internal iliac lymph nodes", "opc": "Deep inguinal lymph nodes", "opd": "Superficial inguinal lymph nodes", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "cf286767-0d81-4316-bb83-6e783c2f5b12", "choice_type": "single"} {"question": "Transistional epithelium is present in", "exp": "Inderbir Singh&;s Human Histology Seventh edition Pg 49 Transitional epithelium is found in renal pelvis and calyces, ureter, urinary bladder and pa of urethra", "cop": 1, "opa": "Renal pelvis", "opb": "Loop of Henle", "opc": "Terminal pa of uretha", "opd": "PCT", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3951f827-63a8-474c-acb5-45b5eb8aaf94", "choice_type": "single"} {"question": "Posterior relation of poal vein", "exp": "The poal vein usually measures approximately 8 cm in adults. It originates behind the neck of the pancreas and is classically formed by the confluence of the superior mesenteric and splenic veins. ref - BDC 6e vol2 pg282 , researchgate.net", "cop": 4, "opa": "1st pa of duodenum", "opb": "Hepatic aery", "opc": "Bile duct", "opd": "IVC", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c71bc934-3ce1-412c-a895-64e521207711", "choice_type": "single"} {"question": "Rotter's lymph nodes are found between", "exp": "Ans: C. Pectoralis major and Pectoralis minorRotter's lymph nodes - Small interpectoral lymph nodes located between pectoralis major & pectoralis minor muscles.Receive lymphatic fluid from muscles & mammary gland.Delivers lymphatic fluid to axillary lymphatic plexus.", "cop": 3, "opa": "Serratus anterior & Trapezius", "opb": "Deltoid & Pectoralis major", "opc": "Pectoralis major and Pectoralis minor", "opd": "Latissimus dorsi and Serratus anterior", "subject_name": "Anatomy", "topic_name": null, "id": "3d4b42b7-603e-4ccb-9d2f-5775d55b85da", "choice_type": "single"} {"question": "Corpora amylacea is seen in", "exp": "Corpora amylacea are small hyaline masses of unknown significance found in the prostate gland, neuroglia, and pulmonary alveoli. They are derived from degenerate cells or thickened secretions and occur more frequently with advancing age. Ref - BDC 6e vol2 pg410 ,researchgate.net", "cop": 1, "opa": "Prostate", "opb": "Seminal vesicle", "opc": "Thymus", "opd": "Testis", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "cf89682a-4aa2-4c7a-bffe-bb819022bd22", "choice_type": "single"} {"question": "The power grip of hand is due to the main function of", "exp": "The power grip is used to do things like carry heavy bags or hold on to a handle. In the power grip, the object is held in the palm of the hand, and the long flexor tendons pull the fingers and the thumb so that they can tightly grasp the object. This grip is made possible by the four other fingers flexing (bending) and, most impoantly, the ability of the thumb to be positioned opposite the fingers. With the hand in this position, larger objects such as a stone or a heavy bottle can be held and moved in a controlled way. The heavier the weight and the smoother the surface is, the more strength is needed to hold and move the object. ref - pubmed.com", "cop": 2, "opa": "Sho flexors", "opb": "Long flexors", "opc": "Lumbricals", "opd": "Palmaris", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "29dd2df8-3746-4814-83cc-a8e25f6ccd7e", "choice_type": "single"} {"question": "One year old male child with cat's reflex and raised IOT", "exp": "Most common age of presentation in Retinoblastoma is within 18 months Refer khurana 6/e", "cop": 3, "opa": "Toxoplasma gondi infection", "opb": "Toxocara canies", "opc": "Retinoblastoma", "opd": "Retinopathy of prematurity", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bfad9dbb-d60a-4e76-8500-3ac468e0c866", "choice_type": "single"} {"question": "Third pa of duodenum is crossed by", "exp": "The third pa, or horizontal pa or inferior pa of the duodenum begins at the inferior duodenal flexure and passes transversely to the left, passing in front of the inferior vena cava, abdominal aoa and the veebral column. The superior mesenteric aery and vein are anterior to the third pa of duodenum. Ref - BDC 6e vol2 pg262", "cop": 4, "opa": "Poal vein", "opb": "Hepatic aery", "opc": "Bile duct", "opd": "Superior mesenteric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ab3c34e9-a1e6-49d6-b33b-fa03cdd04d14", "choice_type": "single"} {"question": "Lymphatic drainage of anterior pa of nose is to", "exp": "Lymphatic from the anterior half of the lateral wall pass to the submandibular nodes,and from the posterior half,to the retropharyngeal and upper deep cervical nodes. Ref BDC volume;3,Sixth edition", "cop": 1, "opa": "Submandibular LN", "opb": "Parotid", "opc": "Pretracheal LN", "opd": "Retropharyngeal LN", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6659cd63-f939-43b0-9f2a-b9100cb9eefa", "choice_type": "single"} {"question": "Pain of ovarian pathology is referred to", "exp": "Pain of ovarian pathology is referred to the periumbilical (T10-T11) area (due to sensory fibres accompanying sympathetic nerves to aoic plexus) along the cutaneous distribution of obturator nerve on inner aspect of thigh (because obturator neurovascular bundle lie lateral to ovary in ovarian fossa).", "cop": 3, "opa": "Back of thigh", "opb": "Anterior thigh", "opc": "Medial thigh", "opd": "Gluteal region", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ea8387ea-ba86-4d80-abd7-21e7176b5fd6", "choice_type": "single"} {"question": "Blood supply of thoracic pa of esophagus", "exp": "OESOPHAGUS-AERIAL SUPPLY 1.The cervical pa including the segment upto the arch of aoa is supplied by the inferior thyroid aeries. 2.The thoracic pa is supplied by the oesophageal branches of the aoa. 3.The abdominal pa is supplied by the oesophageal branches of the left gastric aery. REF:B D Chaurasia's human anatomy,Vol.1.Fifth edition.Pg 270", "cop": 1, "opa": "Aoa", "opb": "Inferior thyroid aery", "opc": "Gastric aery", "opd": "Superior thyroid aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "61a228aa-692d-4838-a8f7-5086971aea16", "choice_type": "single"} {"question": "A patient presents with a penetrating chest wound associated with intrathoracic haemorrhage. A thoracotomy is done by taking an incision in the 41h/51h intercostals space staing 1 cm away from the lateral margin of the sternum.This is done to avoid injury to the", "exp": "C i.e. Internal thoracic aeryIntercostal (external, internal & innermost) muscles (not transverses thoracic) are pierced in pleural taping in mild axillary line.Latissimus dorsi, serratus anterior, rhomboidus major & intercostal muscles are cut in posterolateral thoracotomy whereas pectoralis is cut in anterior & anterolateral approach.Thoracotomy in upper 6 intercostal spaces is done by taking an incision 1 cm lateral to sternum to avoid injury to internal thoracic (mammary) aeryQ.", "cop": 3, "opa": "Pleura", "opb": "Intercostal aery", "opc": "Internal thoracic aery", "opd": "Intercostal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "3c58304b-5277-4037-86fa-ed6517766945", "choice_type": "single"} {"question": "An anaesthetic agent with boiling temperature more than 75 C", "exp": ".", "cop": 4, "opa": "Ether", "opb": "Halothane", "opc": "Cyclopropane", "opd": "Methoxyflurane", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "72743db8-ac33-4ae8-b58a-b73bd1078ade", "choice_type": "single"} {"question": "After ovulation the discharged oocytes and surrounding layer of granulosa cells are known as", "exp": "The corona radiata is the innermost layer of the cells of the cumulus oophorus and is directly adjacent to the zona pellucida, the inner protective glycoprotein layer of the ovum . Its main purpose in many animals is to supply vital proteins to the cell. It is formed by follicle cells adhering to the oocyte before it leaves the ovarian follicle, and originates from the squamous granulosa cells present at the primordial stage of follicular development. The corona radiata is formed when the granulosa cells enlarge and become cuboidal, which occurs during the transition from the primordia to primary stage . These cuboidal granulosa cells, also known as the granulosa radiata, form more layers throughout the maturation process, and remain attached to the zona pellucida after the ovulation of the graafian follicle . For feilization to occur, sperm cells rely on hyaluronidase (an enzyme found in the acrosome of spermatozoa) to disperse the corona radiata from the zona pellucida of the secondary (ovulated) oocyte, thus permitting entry into the perivitelline space and allowing contact between the sperm cell and the nucleus of the oocyte. Ref - Wikipedia.org", "cop": 2, "opa": "Corpus luteum", "opb": "Corona radiata", "opc": "Stigma", "opd": "Zona pellucida", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a2f81f12-c510-45b2-b2b2-5de7c4116a99", "choice_type": "single"} {"question": "The commonest site of peptic ulcer is", "exp": "Conditions also. with peptic ulcer have already been described. Plummer Vinson Paterson Kelly syndrome consists of :- Iron deficiency anemia Dysphasia atrophic oral mucosa, glossitis brittle spoon-shaped fingernails. Typically pts are Woman over 40 yrs of age. Its a Pre-malignant condition* for both oral cavity & esophagus. Ref : S Das textbook, 3/e, p818", "cop": 1, "opa": "1st pa of duodenum", "opb": "2nd pa of duodenum", "opc": "Distal 1/3 of stomach", "opd": "Pylorus of the stomach", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "05ace9ef-3603-4b0f-ba0d-ee4f7523026b", "choice_type": "single"} {"question": "Epitope spreading refers to", "exp": "Ref Robbins 9/e p217 It is a phenomenon in which an immune response against one self antigens causes tissues damage releasing other antigens .and resulting in the activation of lymphocytes by these newly encountered epitope", "cop": 3, "opa": "A type of mechanism of spread of malignant tumor", "opb": "One type of mechanism of HIV dissemination", "opc": "A mechanism for the persistence and evolution of autoimmune disease", "opd": "One of the mechanism of apoptosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b9826a27-2eb7-429d-8a66-ce28492caed9", "choice_type": "single"} {"question": "In carcinoma head of pancreas nausea and vomiting is due to", "exp": "PRESENTING SYMPTOM FREQUENCY Jaundice Weight loss Abdominal pain Nausea/vomiting Pruritus Fever Gastrointestinal bleeding Ref: Sabiston 20th edition Pgno: 1544", "cop": 1, "opa": "External compression of duodenum", "opb": "Poal vein infiltration", "opc": "Proliferation and infiltration into duodenum", "opd": "Chemotherapy related", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2724f661-8e1b-44b1-80d4-4f3b93aa3847", "choice_type": "single"} {"question": "Final centre for horizontal movements of eye is", "exp": ".", "cop": 1, "opa": "Abducent nucleus", "opb": "Trochlear nucleus", "opc": "Oculomotor nucleus", "opd": "Vestibular nucleus", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e84728a6-0527-42d8-af25-eb0dc96509c7", "choice_type": "single"} {"question": "For oral iron supplements used for iron deficiency anemia", "exp": "Refer Katzung 10/e p 530 Tolerable doses of elemental iron is 200mg per day Mass of elemental iron is more impoant in determining Daily Dose Treatment with oral iron should be continued even after reaching the desired hemoglobin level", "cop": 1, "opa": "Tolerable dose will deliver 40 to 60 mg of iron per day", "opb": "Mass of total salt is impoant in determining Daily Dose", "opc": "Treatment should be stopped as soon as normal hemoglobin levels is reached", "opd": "Desired rate of hemoglobin improvement is 0.5 mg per day", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "43a34fbf-cf51-40a7-b8b1-9fb12ee08c51", "choice_type": "single"} {"question": "Node of Ranvier means", "exp": "- Nodes of Ranvier or Myelin sheath gaps, are the gaps (approximately 1 micrometer in length) formed between the myelin sheaths generated by different cells. O A myelin sheath is a many-layered coating, largely composed of a fatty substance called myelin,that wraps around the axon of a neuron and very efficiently insulates it. O At nodes of Ranvier, the axonal membrane is uninsulated and therefore capable of generating electrical activity. O Since fat serves as a good insulator, the myelin sheaths speed the rate of transmission of an electrical impulse along the axon. O Electrical impulse jumps from one node to the next at a rate as fast as 120 meters/ second. O This rapid rate of conduction is called salutatory conduction. O Myelinated axons are rare in the autonomic nervous system. Inveebrates do not have myelinated sheaths.", "cop": 1, "opa": "Gap between two Schwann cells", "opb": "Indentation Schwann cell due to synapsing of adjacent unipolar neuron", "opc": "Gaps between dendrites and Schwann cells", "opd": "Gaps between Schwann cell and axon", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "563f3257-78b4-4c56-9a16-e6a18a668a88", "choice_type": "single"} {"question": "Teratomas may arise from the aberrant migration of", "exp": "Epiblast cells form the primordial germ cells, which migrate from the region of primitive streak to the region of future gonads to form the gametes like sperm & oocyte.Abnormal remnants of epiblast/primordial germ cells at the primitive streak or their aberrant migration lead to forma on of teratomas.", "cop": 1, "opa": "Epiblast", "opb": "Hypoblast", "opc": "Cytotrophoblast", "opd": "Syncy otrophoblast", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cbdb2a36-bde6-4380-8ea6-056683396542", "choice_type": "single"} {"question": "Great cerebral vein of Galen formed by the union of", "exp": "Great cerebral vein: This is a single median vein. It is formed by the union of the two internal cerebral veins. It terminates in the straight sinus. Its tributaries include the basal veins and veins from the pineal body, the colliculi, the cerebellum and the adjoining pa of the occipital lobes of the cerebrum.Ref: BD Chaurasia; Volume 3; 6th edition; Page no: 388", "cop": 2, "opa": "Superfcial middle cerebral vein", "opb": "Internal cerebral vein", "opc": "Anterior cerebral vein", "opd": "Middle cerebral vein", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "308518c7-118f-4283-878e-9528d5771bfe", "choice_type": "single"} {"question": "First stage of lung development is", "exp": "Lung organogenesis is pa of the embryonal period. While fetal lung development consists in the pseudoglandular, canalicular and saccular stages, postnatal lung development comprises the stages of classical and continued alveolarization, as well as of microvascular maturation. The phases of lung development are mainly based on morphological criteria. Because most processes during lung development sta proximal and extend into the periphery, all phases of lung development overlap . Ref - pubmed.com", "cop": 1, "opa": "Pseudoglandular", "opb": "Tubular", "opc": "Alveolar", "opd": "Canalicular", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "4d3bf194-5d4f-4748-885a-59e0477843b8", "choice_type": "single"} {"question": "After the pericardial sac has been opened anteriorly during surgery, by passing a surgical clamp through the transverse sinus, surgeons can stop/dive circulation of blood in", "exp": "During surgery, a clamp is passed through the transverse sinus stops or dives the blood flow from the aoa and pulmonary trunk. Transverse pericardial sinus seperates the aerial end of the hea tube from the venous end. Aoa and pulmonary trunk lie anterior to the sinus and superior vena cava lies posterior to it. Therefore, during surgery, a clamp is passed through the transverse sinus stops or dives the blood flow from the aoa and pulmonary trunk. Ref: Gray's Anatomy 41st edition Pgno: 183", "cop": 3, "opa": "Superior an inferior vena cava", "opb": "Aoa and pulmonary veins", "opc": "Aoa and pulmonary trunk", "opd": "SVC and pulmonary veins", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "8c034f48-5e57-44d9-b37b-39409847d029", "choice_type": "single"} {"question": "The sequence of commonest fractured sites of Mandible is", "exp": "The mandible is commonly fractured at the canine socket where it is weak. Involvement of the inferior alveolar nerve in the callus may cause neuralgic pain, and if the nerve is paralyzed, the area supplied by the mental nerve becomes insensitive. The next common fracture of the mandible occurs at the angle.Reference: Chourasia; 6th edition; 35th page; 1.29 Figure", "cop": 3, "opa": "Angle, Neck, Canine fossa", "opb": "Canine fossa, Neck, Angle", "opc": "Canine fossa, Angle, Neck", "opd": "Neck, Canine fossa, Angle", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dd0850f7-f7a2-40d0-8684-21fe331c016a", "choice_type": "single"} {"question": "Maxillary prominence develops in", "exp": null, "cop": 1, "opa": "1st pharyngeal arch", "opb": "1st pharyngeal groove", "opc": "1st pharyngeal pouch", "opd": "1st pharyngeal membrane", "subject_name": "Anatomy", "topic_name": null, "id": "b30d20a7-38b3-44ce-ab13-36e9bf6ccdbd", "choice_type": "single"} {"question": "After 72 hours of Myocardial infarction, the predominant cells are", "exp": ".", "cop": 2, "opa": "Mast cells", "opb": "Macrophages", "opc": "Lymphocytes", "opd": "Leukocytes", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "231ec7e3-524f-4642-a460-4733e6637670", "choice_type": "single"} {"question": "Solid and largest lymphatic organ of the body is", "exp": "(A) Spleen# Largest lymphatic organ in the human body is the spleen.> Primary function of the spleen is to purify the blood and store blood cells. It helps the immune system identify and combat foreign antibodies.> The spleen consists of white pulp and red pulp. The white pulp generates blood cells and synthesizes antibodies, and the red pulp removes old blood cells and filters the blood.", "cop": 1, "opa": "Spleen", "opb": "Thymus", "opc": "Lymph node", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "41585522-f8c5-4f30-b48e-a37af93c0819", "choice_type": "single"} {"question": "Intrinsic muscles of the tongue are derived from", "exp": "occipital somites Most of the tongue muscles are derived from myoblasts that migrate from the occipital somites.Embryological Origin of the TongueThe tongue's embryonic orgin is derived from first 4 pharyngeal arches contributing different components.Anterior 2/3\" or body of tongue: is derived from 3 lingual buds- the median tongue bud (tuberculum impar) and 2 lateral lingual swellings developing at each side of the median tongue bud. All arising from the la pharyngeal arch. The lateral tongue buds rapidly increase in size, merge with each other, and overgrow the median tongue bud. The merged distal tongue buds form the anterior 2/3rd of the tongue. The median tongue bud forms no recognizable pa of the adult tongue. Since the mucosa covering the ant. 2/3rd of the tongue originates from the first pharyngeal arch; sensory innervation to this area is by the mandibular branch of the trigeminal nerve. (Taste sensation to the anterior 2/3rd of the tongue is provided by the chorda tympani branch of the facial nerve).Post 1/3\" or root of the tongue: is formed from two median elevations;- The copula arising from the 2\"d pair of branchial arches, just caudal to the foramen ceacum.- The hypopharyngeal or hypobranchial eminence developing caudal to the copula from the 3rd and dh pair of arches.As the tongue develops the copula is gradually overgrown by the hypopharyngeal eminence and disappears. As a result, the post pa of the tongue develops from the hypopharyngeal eminence( the 3rd and 4th pharyngeal arches) . Thus the sensory nerve supply to this pa of tongue is from the glossopharyngeal nerve.(taste sensation is also carried by the glossopharyngeal nerve).Pharyngeal arch mesenchyme forms the connective tissue and vasculature of the tongue. Some of the tongue muscles probably develop in situ from mesenchyme, but most develop from myoblasts that migrate from the occipital myotomes. The hypoglossal nerve accompanies the myoblasts during their migration and innervates the tongue muscles.The Nerve Supply of the Tonguea. Motor nerve- All the intrinsic & extrinsic muscles, except the palatoglossus, are supplied by the hypoglossal nerve. The palatoglossus is supplied by the cranial pa of the accessory nerve through the pharyngeal plexus.b. Sensory nerves:- Anterior 2/3 of tongue - The lingual nerve is the nerve of general sensation and the chorda tympani is the nerve of taste for the anterior two-thirds of the tongue.- Posterior 1/3 of tongue - The glossopharyngeal nerve is the nerve for both general sensation and taste for the posterior 1/3 of the tongue.- The posterior-most pa of the tongue is supplied by the vagus nerve through the internal laryngeal branch. You can also see animated embryological development of tongue at following sites: class=\"Style2\"> 1 2/animations/contents.htm", "cop": 3, "opa": "2 \"d branchial cleft", "opb": "Pharyngeal arch mesenchyme", "opc": "Occipital somites", "opd": "Cervical somites", "subject_name": "Anatomy", "topic_name": null, "id": "87349764-2797-4dc2-9ad7-69614118fb8d", "choice_type": "single"} {"question": "The aerial blood glucose concentration in normal humans after a meal is in the range of", "exp": ".", "cop": 3, "opa": "30 to 50 mg/dL", "opb": "50 to 70 mg/dL", "opc": "120 to 150 mg/dL", "opd": "220 to 250 mg/dL", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2cf55062-9eb0-4341-b5ff-b73da3a17f48", "choice_type": "single"} {"question": "NOT a content of superior mediastinum", "exp": "Mediastinum refers to the space between two lungs in thorax. SUPERIOR MEDIASTINUM Space above 2nd costal cailage CONTENTS: thymus, arch of aoa, superior venacava, pulmonary aeries, esophagus, trachea, T1 - T4 veebra, PICA - 1, 2. INFERIOR MEDIASTINUM Space below superior mediastinum, again divided into anterior, middle and posterior mediastinum. CONTENTS: pulmonary trunk, bronchus, thymus, hea, ascending aoa, PICA 3 - 12 esophagus, descending aoa, T5 - T12 veebra. Angle between manubrium of sternum & body of sternum is called angle of louis, which is 1630.", "cop": 1, "opa": "Pulmonary trunk", "opb": "Thymus", "opc": "Left superior intercostal aery", "opd": "Arch of aoa", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "d212f837-ea72-4809-ab4e-a0629006bc1a", "choice_type": "single"} {"question": "F 10 denotes in ICD 10 denotes", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref.Internation Classification disorders, 10 edition", "cop": 2, "opa": "organic disorders", "opb": "substance use disorders", "opc": "mood disorders", "opd": "anxiety disorders", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c7adc0ab-5385-4a89-9d91-987c5ba937c6", "choice_type": "single"} {"question": "Annerix V on non permeable cell is indicative of", "exp": "Ref, Robbins 8/ep27,9/ep56 Apoptotic cells express phosphatidylserine in the outer layers of their plasma membrane.This phospholipids move out from the inner layer where it is recognised by number of receptors on the phagocytes.", "cop": 1, "opa": "Apoptosis", "opb": "Necrosis", "opc": "Cell entering replication phase", "opd": "Cell cycle arrest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e659e4f4-cd09-4a55-a982-dfa8e6ce4dd7", "choice_type": "single"} {"question": "This drug can clear trip trypansomes from Blood and lymph nodes and is active in late CNS stage of African sleeping sickness. it is", "exp": "Ref-Katzung 10/e p863 Treatment of trypansomes is African sleeping sickness Early haemolymphatic stage :Suramin Late CNS stage: melarsoprol South American disease (chagas disease):nifuimox", "cop": 2, "opa": "Emetine", "opb": "Melarsoprol", "opc": "Nifuimox", "opd": "Suramin", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "c7e2b8c0-b2e5-43c5-817a-651dbac93b6b", "choice_type": "single"} {"question": "Bleeding vessel in haemorrhoids is", "exp": "Bleeding vessel in haemorrhoids is superior rectal vein which is a branch of inferior mesenteric vein at the level of rectum. Dilation of these vessels leads to bleeding leading to internal haemorrhoids. Veins are better option than aery.", "cop": 2, "opa": "Superior rectal aery", "opb": "Superior rectal vein", "opc": "Middle rectal aery", "opd": "Middle rectal vein", "subject_name": "Anatomy", "topic_name": "Pelvis and Perineum 3", "id": "39860116-7589-4aa9-94e1-7e56a9332a0d", "choice_type": "single"} {"question": "Bag of membranes ruptures", "exp": "Membranes usually rupture after full dilatation of cervix or sometimes even beyond in second stage", "cop": 2, "opa": "Before full dilatation of cervix", "opb": "After full dilatation of cervix", "opc": "After head is engaged", "opd": "With excessive show", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "3726749d-1b21-405e-a827-0b7a37f99906", "choice_type": "single"} {"question": "Lining of oesophagus is", "exp": null, "cop": 4, "opa": "Stratified columnar", "opb": "Stratified cuboidal", "opc": "Keratinised stratified squamous", "opd": "Non keratinised stratified squamous", "subject_name": "Anatomy", "topic_name": null, "id": "c07d2646-578b-4d38-a949-d85d409e939f", "choice_type": "single"} {"question": "The superior vesical aeries are direct branches of the", "exp": "The umbilical aery is a branch of the internal iliac aery. In the fetus, the umbilical aery passes over the bladder and continues up the anterior body wall to the umbilical cord and out to the placenta. As it passes the bladder, it gives rise to the superior vesical aeries. After bih, the pa of the aery distal to the bladder becomes fibrous, but the proximal pa remains patent and continues to supply the bladder.", "cop": 2, "opa": "Internal iliac aery", "opb": "Umbilical aery", "opc": "Internal pudendal aery", "opd": "External pudendal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "98219ce4-c5a4-46c2-8093-812d2546063b", "choice_type": "single"} {"question": "Crura of Penis is supplied by", "exp": "Dorsal artery of penis supplies the skin and fascia.\nDeep artery of penis supplies the crura.", "cop": 2, "opa": "Dorsal artery of penis", "opb": "Deep artery of penis", "opc": "External pudendal artery", "opd": "Obturator artery", "subject_name": "Anatomy", "topic_name": null, "id": "71747f3c-87b2-4665-8faf-cb6874b08007", "choice_type": "single"} {"question": "Contents of posterior triangle of neck", "exp": "Contents of posterior triangle of neck :\n\nOccipital artery.\nSpinal accessory nerve.\nSubclavian vessels.\nTrunks of brachial plexus.\nGreat auricular nerve, lesser occipital nerve, supraclavicular nerve, transverse cutaneous nerve.\nExternal jugular vein.", "cop": 2, "opa": "Occipital artery, spinal accessory nerve, hypoglossal, ascending pharyngeal artery", "opb": "Occipital artery, lesser occipital nerve, subclavian artery, spinal accessory nerve", "opc": "Occipital artery, spinal accessory nerve, subclavian artery, hypoglossal nerve", "opd": "Occipital artery, Lesser occipital nerve, ascending pharyngeal artery, vagus nerve", "subject_name": "Anatomy", "topic_name": null, "id": "7b119fe3-05b2-42c0-b0c0-8173651d9b6a", "choice_type": "single"} {"question": "Most common vascular tumor in AIDS patient is", "exp": "Ref Robbins 8/e 523_524 KS is caused by a virus called human herpes virus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpes virus (KSHV). KS develops when infected cells that line lymph or blood vessels begin to divide without stopping and spread into surrounding tissues. Whereas most cancers begin in one pa of the body and may later spread to other areas, KS usually appears as lesions (abnormal bumps, spots or patches) on the skin or on mucosal surfaces (such as inside the mouth or in the genitals). Lesions can also develop in other pas of the body, such as in the lungs, lymph nodes or gastrointestinal tract. Having visible KS lesions can be upsetting. Nonetheless, they may develop very slowly without causing any serious complications. If KS is confined to the skin or lymph nodes without causing any swelling, it usually responds very well to treatment with anti-HIV drugs. Infection with HHV-8, the virus which causes KS, is widespread among gay men and in African countries. The virus can be found in saliva and may be passed on during sex, including through wet kissing, oral sex, and using saliva as a lubricant during sex. It can also be spread when adults pre-chew food for infants. There isn't a vaccine to prevent HHV-8 infection. A normally functioning immune system can usually keep HHV-8 infections under control and suppress the abnormal growth of cells into KS lesions. Most people who have HHV-8 never get KS. However, when the immune system is weakened and an unhelpful activation of the immune system in response to HHV-8 occurs, KS may develop. Generally, KS is a rare cancer in people who don't have HIV. Nonetheless, cases do occur in HIV-negative people, paicularly in people who take medications that suppress the immune system (such as coicosteroids). It is also one of the most common cancers in African countries, with large numbers of cases in people who don't have HIV.", "cop": 1, "opa": "Kaposi's sarcoma", "opb": "Angiosarcoma", "opc": "Lymphangioma", "opd": "Lymphoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8a555407-dd31-46a2-a0d5-54de15c5f279", "choice_type": "single"} {"question": "Following antineoplastic drugs should not be administered to a chronic alcoholic patient due to risk of development disulfiram like reaction", "exp": "Ref-KDT 6/e p827 Procarbazine is a chemotherapy medication used for the treatment of Hodgkin's lymphoma and brain cancers. For Hodgkin's it is often used together with chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine You should avoid the use of alcohol while being treated with procarbazine, as alcohol may increase some of the nervous system side effects such as dizziness, drowsiness, and difficulty concentrating.", "cop": 2, "opa": "Dacarbazine", "opb": "Procarbazine", "opc": "Melphalan", "opd": "Hydroxyurea", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "1760406f-927f-440c-8d73-6f613e58ff1f", "choice_type": "single"} {"question": "Epithelial lining of the Tonsil is", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:144The palatine tonsils Each palatine tonsils consists of diffuse lymphoid tissue in which lymphatic nodules are present. the lymphoid tissue is covered by stratified squamous epithelium continuous with that of the mouth and pharynx", "cop": 2, "opa": "Cuboidal", "opb": "Squamous epithelium without Keratinisation", "opc": "Squamous epithelium with Keratinisation", "opd": "Columnar", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "383f838d-308c-4fb2-ad84-4bd9406fd895", "choice_type": "single"} {"question": "First cellular change in hypoxia", "exp": "Ref, Robbins 8/e p18;7/e p15;9/ep45", "cop": 1, "opa": "Decreased oxidative phosphorylation in mitochondria", "opb": "Cellular swelling", "opc": "Alteration in cellular membrane permeability", "opd": "Clumping of nuclear chromatin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c2eee3ea-7dd9-4560-9428-3bb0ed35218a", "choice_type": "single"} {"question": "Posterior superior alveolar aery is branch of", "exp": "B i.e. Palatal branch of maxillary aery", "cop": 2, "opa": "Nasal branch of maxillary aery", "opb": "Palatal branch of maxillary aery", "opc": "Mandibular aery", "opd": "Inferior alveolar aery", "subject_name": "Anatomy", "topic_name": null, "id": "fcc78812-5acc-4291-81b0-7e4766161b54", "choice_type": "single"} {"question": "Following are required for normal growth", "exp": "A,B,D are answers Ref Robbins 7/e p290; 9/e p280 A proto-oncogene is a normal gene that could become an oncogene due to mutations or increased expression. Proto-oncogenes code for proteins that help to regulate the cell growth and differentiation. Proto-oncogenes are often involved in signal transduction and execution of mitogenic signals, usually through their protein products. Examples of proto-oncogenes include RAS, WNT, MYC, ERK, and TRK.", "cop": 1, "opa": "Proto oncogene", "opb": "Tumor suppressor genes", "opc": "Oncogenes", "opd": "DNA repair genes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dc1545fe-bce0-4d01-b589-ea9e3b07308d", "choice_type": "single"} {"question": "Cranial part of accessory nerve supplies", "exp": "Sternocleidomastoid and trapezius develop from branchial arch mesoderm and are supplied by spinal part of accessory nerve. \nLevator scapulae are supplied by a branch from dorsal scapular nerve and branches from C3, C4.", "cop": 1, "opa": "Sternocleidomastoid", "opb": "Trapezius", "opc": "Levator scapulae", "opd": "Levator palatini", "subject_name": "Anatomy", "topic_name": null, "id": "60a664da-1648-4d51-9901-5ce1131d3cb8", "choice_type": "single"} {"question": "Bigelow's ligament is at", "exp": "C. i.e. Hip joint", "cop": 3, "opa": "Knee joint", "opb": "Shoulder joint", "opc": "Hip joint", "opd": "Ankle joint", "subject_name": "Anatomy", "topic_name": null, "id": "e86ac531-b5f4-414d-b784-5d6b0f8bad24", "choice_type": "single"} {"question": "Medial rotator of thigh at hip joint is", "exp": "Gluteus medius, Gluteus minimus, Tensor fascia lata (collectively referred to as TRIO muscles)- Medial rotators of thigh Obturator internus, Obturator externus, Gluteus maximus -lateral rotators of thigh.", "cop": 4, "opa": "Obturator externus", "opb": "Obturator internus", "opc": "Gluteus maximus", "opd": "Gluteus minimus", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "43581fb0-69d6-4ca6-8f6f-c6061e939aa4", "choice_type": "single"} {"question": "The drug of choice for supraventricular tachycardia is", "exp": "Refer katzung 11e 243,244 KDT 6/e p517 Adenosine is drug of choice for paroxysmal supraventricular tachycardia termination Verapamil is a drug of choice for prophylaxis of paroxysmal supraventricular tachycardia and for the management of sustained supraventricular tachycardia", "cop": 1, "opa": "Verapamil", "opb": "Diltiazem", "opc": "Digoxin", "opd": "Phenytoin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "71b5bb49-f0c5-4a3c-8360-958501d70216", "choice_type": "single"} {"question": "Fibro cailage is found in", "exp": "Fibrocailage is shock absorber which provides strength to cailage and is found in Interveebral disc. Costal cailage and nasal septum are made up of Hyaline Cailage. Auditory tube has elastic cailage.", "cop": 3, "opa": "Costal cailage", "opb": "Nasal septum", "opc": "Interveebral disc", "opd": "Auditory tube", "subject_name": "Anatomy", "topic_name": "Cailage tissue & cell junctions", "id": "371cb226-675f-4f89-a8e1-861cd7287883", "choice_type": "single"} {"question": "Disease or infarction of neurologist tissues causes it to be replaced by", "exp": "Neuroglia astrocytes are the principal cells in the central nervous system responsible for reactioj to injury repair and scar formation in the brain. They perform function similar to fibroblasts in the CNS Refer Robbins page no 1252", "cop": 2, "opa": "Fluid", "opb": "Neuroglia", "opc": "Proliferation of adjacent nerve cells", "opd": "Blood vessel", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "7c9b0a2d-9f7c-40c5-a70f-e2ebc9a3afb8", "choice_type": "single"} {"question": "The basal forebrain nuclei and the pedunculopontine nuclei are similar in that neurons within them", "exp": ".", "cop": 4, "opa": "Are major inputs to the striatum", "opb": "Receive innervation from the cingulate gyrus", "opc": "Process information related to language construction", "opd": "Utilize acetylcholine as their neurotransmitter", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "49bb55e9-c425-478e-9d80-122b0e7cc429", "choice_type": "single"} {"question": "Memory T cell can be identified using the following marker", "exp": ".", "cop": 4, "opa": "CD45RA", "opb": "CD45RB", "opc": "CD45RC", "opd": "CD45RO", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "38a71d46-d7fa-41e5-9c2e-58dec94e1538", "choice_type": "single"} {"question": "Regarding termination of drug action", "exp": "Ref-KDT 6/e p23 Action of drug can be terminated by hepatic metabolism or by anal excretion. Most of the dexa inactivated by metabolism. However some Ducks may be activated from inactive form (prodrugs) and others may produce active metabolite Some drugs main activate from Blood example decoction lives bloodstream and enters the hea to produce it's action", "cop": 3, "opa": "Drugs must be excreted from the body to terminate their action", "opb": "Metabolism of drugs always abolishes their Pharmalogical activity", "opc": "Hepatic metabolism and renal excretion are the two most impoant mechanism involved", "opd": "Distribution of a drug out of bloodstream terminated drugs effect", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "1c636da2-775e-422b-958c-5296113b4c08", "choice_type": "single"} {"question": "Irreversible injury in cell is", "exp": "Ref, Robbins 8/e p13-14;7/ep11,9/ep47", "cop": 1, "opa": "Deposition of ca ++ in mitochondria", "opb": "Swelling", "opc": "Mitotic figure", "opd": "Ribosomal detachment", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "43e136bc-5d47-4cd4-a576-bb88850e23e4", "choice_type": "single"} {"question": "Middle meningeal vessel damage results in", "exp": "Extradural hematoma (EDH), also known as an epidural hematoma, is a collection of blood that forms between the inner surface of the skull and outer layer of the dura, which is called the endosteal layer. They are usually associated with a history of head trauma and frequently associated skull fracture. The source of bleeding is usually aerial, most commonly from a torn middle meningeal aery. EDHs are typically biconvex in shape and can cause a mass effect with herniation. They are usually limited by cranial sutures, but not by venous sinuses. Both CT and MRI are suitable to evaluate EDHs. When the blood clot is evacuated promptly (or treated conservatively when small), the prognosis of EDHs is generally good. Intracranial venous extradural hemorrhages and spinal epidural hemorrhages are discussed separately Refer Robbins page no 1261 9th edition", "cop": 2, "opa": "Subdural haemorrhage", "opb": "Extra dural hemorrhage", "opc": "Subarachnoid hemorrhage", "opd": "Intracerebral haemorrhage", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "469fb7b1-90b6-4147-834f-812081547b63", "choice_type": "single"} {"question": "Peripheral necrosis of liver is caused by", "exp": "Hepatocellular damageExamplesMicrovascular fatty changeTetracycline, salicylates, yellow phosphorus, ethanolMacrovascular fatty change Ethanol, methotrexate, amiodaroneCentrilobular necrosisBromobenzene , CCL4,acetaminophen,halothane ,rifampinDiffuse or massive necrosisHalothane, isoniazid, acetaminophen, methyldopa, trinitrotoluene, Amanita phalloides toxinHepatitis Methyldopa, isoniazid, nitrofurantoin, phenytoin, oxyphenisatinFibrosis-cirrhosis Ethanol, methotrexate, amiodarone, most drugs that cause chronic hepatitisGranuloma formation Sulfonamides, methyldopa, quinidine, phenylbutazone, hydralazine, allopurinolCholestasis Chlorpromazine, anabolic steroids, erythromycin, estolate, OCP, organic arsenicalsPeripheral necrosisPhosphorus (Refer: Robbins & Cotran's - Pathologic Basis of Disease, SAE, 1st edition, Vol II-pg no: 840 &841)", "cop": 3, "opa": "Carbon tetrachloride", "opb": "Benzene", "opc": "Phosphorus", "opd": "Rifampicin", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1d03cef3-bb65-4b4d-9565-a4dd9daa1758", "choice_type": "single"} {"question": "Among the muscles of TMJ the following muscle opposing stabilizing and antagonistic muscle force as far as the disc is concerned", "exp": null, "cop": 3, "opa": "Medial pterygoid", "opb": "Temporalis", "opc": "Lateral pterygoid", "opd": "External pterygoid", "subject_name": "Anatomy", "topic_name": null, "id": "31fa1fdb-effd-4f00-8a93-f306b066f96d", "choice_type": "single"} {"question": "hyper ammonemia is a side effect of", "exp": "LETHAL SIDE EFFECTS OF VALPROATE - Hyperammonemia - Pancreatitis - Hepatic failure - Neural tube defects - Thrombocytopenia MINOR SIDE EFFECTS OF VALPROATE - Hair loss - PCOD - WEIGHT GAIN - TREMORS Ref.kaplon and sadock, synopsis of psychiatry,11 th editioon, pg no.935", "cop": 1, "opa": "valproate", "opb": "amitriptilline", "opc": "amisulpride", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "b965e3af-a1d1-4468-94a3-edd880ed4890", "choice_type": "single"} {"question": "Vein used to bypass the coronary aery", "exp": "Varicose veins are due to the touosity of the long saphenous vein and occur mostly due to prolonged standing.The long saphenous vein is used to bypass the coronary aery after inveing the vein.Ref: Chaurasia; Volume 2; 6th edition; Page no: 135", "cop": 1, "opa": "Long saphenous vein", "opb": "Sho saphenous vein", "opc": "Soleal vein", "opd": "Tibial vein", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "aea05576-02c1-4748-a7a3-2ed929d00d33", "choice_type": "single"} {"question": "Nuclear bag fibre detects", "exp": "(Refer Q 5 AIIMS Nov'14)", "cop": 1, "opa": "Sense dynamic length of muscle", "opb": "Involved in reciprocal innervations", "opc": "Alpha motor neuron stimulation", "opd": "Senses muscle tension", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cb0f4dba-99ad-4668-a901-750814374700", "choice_type": "single"} {"question": "Insulin resistance in liver disease is due to", "exp": "Refer Robbins page no Insulin resistance is defined as the failure of target tissues to respond normally to insulin. It leads to decreased uptake of glucose ik muscle reduced glycolysis and fatty acid oxidation I'm the liver and inability to suppress hepatic gluconeogenesis", "cop": 2, "opa": "Decreased insulin resistance", "opb": "Steatosis", "opc": "Hepatocyte dysfunction", "opd": "Decreased C peptide level", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "de0a1c9c-c45b-40fe-a29d-d1daee690e75", "choice_type": "single"} {"question": "Total duration of antibiotics in acute osteomyelitis is", "exp": "Teatement is staed with , IV antibiotics until condition begins to improve or Crp values return to normal, usually for 2 weeks. Thereafter antibiotics ae given orally for another 4 weeks. Change of antibiotics or surgery is considered, if no improvement occurs within 48hrs of antibiotics. ref : maheswari 9th ed", "cop": 3, "opa": "4 weeks", "opb": "2 weeks", "opc": "6 weeks", "opd": "8 weeks", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "0d3d0b40-6bcf-4145-ac1d-d74d31d087f1", "choice_type": "single"} {"question": "Primitive streak develops from", "exp": "Around day 14, the epiblast cells form primitive streak .", "cop": 3, "opa": "Mesoderm", "opb": "Hypoblast", "opc": "Epiblast", "opd": "Neural plate", "subject_name": "Anatomy", "topic_name": "General Embryology 2", "id": "ca2cfafc-6c7d-452b-984c-ecfd09a10802", "choice_type": "single"} {"question": "Bleeding vessel in hemorrhoids is (FMGE Dec 2018)", "exp": "Blood of hemorrhoids is from vein > Aery > sinusoids. Hemorrhoids - engorgement of venous plexus at / inside anal sphincter. It has slight genetic predisposition, but obesity, straining during bowel movements, sedentary life- style can predispose to them. Symptoms -irritation, pain, swelling. External hemorrhoids: Hemorrhoids occurring at anal verge (distal boundary of anal canal below pectinate line) Normally have low tendency to bleed on straining at stool. Bleeding comes from inferior rectal vein. Internal hemorrhoids: Occur inside the rectum (above pectinate line) have high tendency to bleed. Bleeding from \"superior rectal vein\" Prolapsed hemorrhoids are internal hemorrhoids that pass outside anal canal & form lump, which may undergo thrombosis & become painful.", "cop": 2, "opa": "Superior rectal aery", "opb": "Superior rectal vein", "opc": "Middle rectal aery", "opd": "Middle rectal vein", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "992bb371-f6d4-4b97-84dd-40be84a11f31", "choice_type": "single"} {"question": "Inveor of foot is", "exp": "Eversion: movement in which the lateral border of the foot is elevated so that the sole faces laterally. Inversion: movement in which the medial border of the foot is elevated so that the sole faces medially. In eversion and inversion, the entire pa of the foot below the talus moves together. Inversion is accompanied by plantar flexion of the foot and adduction of the forefoot.Eversion is accompanied by the dorsiflexion of the foot and adduction of the forefoot. JOINTS TAKING PA:-Subtalar Talocalcaneonavicular Transverse talar AXIS:- These movements takes place around an oblique axis which runs forwards, upwards and medially, passing from the back of the calcaneum, through sinus tarsi, to emerge at the superomedial aspect of the neck of the talus. The obliquity of the axis pay accounts for the adduction, abduction, plantar flexion and dorsiflexion which are associated with these movements. RANGE:-Inversion is more free than eversion The range of movements is increased in plantar flexion. MUSCLES PRODUCING MOVEMENTS:- Muscles- Main Accessory Inversion Tibialis anterior Tibialis posterior FHL FDL Eversion Peroneus longus Peroneus brevis {Reference:BDC 6E}", "cop": 1, "opa": "Tibialis posterior", "opb": "Peroneus teius", "opc": "Peroneus brevis", "opd": "Gastrocnemius", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "c5770f93-938a-4521-a4cb-c9a5e91e2c4d", "choice_type": "single"} {"question": "Tract ABSENT in superior cerebellar peduncle", "exp": "* Dorsal spinocerebellar fibers pass through inferior (not superior) cerebellar peduncle. Peduncle Afferent Middle cerebellar peduncle Coico ponto cerebellar tract Inferior cerebellar peduncle Olivocerebellar tract Dorsal Spinocerebellar Superior cerebellar peduncle Ventral spinocerebellar Tectocerebellar * Efferent fiber of superior cerebellar peduncle : Dento Rubro thalamic tract", "cop": 3, "opa": "Tecto-cerebellar", "opb": "Dentato thalamic", "opc": "Dorsal spinocerebellar", "opd": "Ventral spinocerebellar", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "32256ee2-b67d-4081-955f-5547ce9b960a", "choice_type": "single"} {"question": "Inferior rectal aery is a branch of", "exp": "The inferior rectal aery arises near the posterior end of the pudendal canal from internal pudendal aery, and accompanies the nerve of the same name.The aery supplies the skin and muscles of the anal region, and anastomoses with the superior and middle rectal aeries And the other branches are - The perineal aery ( arises near the anterior end of the pudendal canal ), The aery of the penis or theclitoris Ref : B D Chaurasia's Human Anatomy, seventh edition , volume 2 , pg. no. 397", "cop": 4, "opa": "Inferior mesenteric aery", "opb": "Superior mesenteric aery", "opc": "Celiac trunk", "opd": "Internal pudendal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "dd6bd819-1146-4013-b05e-cc648bfeacc6", "choice_type": "single"} {"question": "Sphincter and dilator pupillae develops from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH tenth edition Derivatives of neuroectoderm: R-Retina O-Optic stalk/optic nerve M-Muscles of iris(sphicter and dilator pupillae) E-Epithelium of iris/ciliary body", "cop": 1, "opa": "Neuroectoderm", "opb": "Surface ectoderm", "opc": "Mesoderm", "opd": "Endoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7b703cea-3645-4bfd-bd8e-cf8bf6feaf60", "choice_type": "single"} {"question": "Stage of 16 cells is", "exp": "A morula is distinct from a blastocyst in that a morula (3-4 days post feilization) is a 16-cell mass in a spherical shape whereas a blastocyst (4-5 days post feilization) has a cavity inside the zona pellucida along with an inner cell mass", "cop": 2, "opa": "Embryo", "opb": "Morula", "opc": "Zygote", "opd": "Blastocyst", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ce304b93-24ce-4377-bd5d-95a7f1a7d30c", "choice_type": "single"} {"question": "Left Kidney is preferred for transplantation because", "exp": "The left kidney is preferred because of implantation advantages associated with a longer renal vein making anastomosis easier Also know, procurement of kidney, In a brainstem dead donor, the organ to be procured should be preserved to maintain its functional integrity. For this purpose the organ should be perfused with organ preservative solution twice before it is transplanted to the recipient. The first perfusion is done just after the abdomen is opened at laporotomy and the second perfusion is done just after the organ has been removed from the donor. Commonly used preservative solutions include UW solution (University of Wisconsin) and Eurocollins solution. After removal from the donor, the organ is placed in two sterile bags and stored at 0-4degC by immersion in ice while they are transpoed to the recipient centre Ref srb's manual of surgery 5e p993 , Internet", "cop": 1, "opa": "Longer renal Vein", "opb": "Higher location", "opc": "Ease of surgery due to anatomical relations", "opd": "To prevent damage to liver", "subject_name": "Anatomy", "topic_name": "Urology", "id": "89ad1c15-d1df-4b13-ba60-60312adf1535", "choice_type": "single"} {"question": "Largest carpal bone is", "exp": "CARPAL BONES:-8 in number.Proximal row:-1. Scaphoid- boat-shaped.2. Lunate- moon shape/ crescentic.3. Triquetral-pyramidal.4. Pisiform-pea shaped.Distal row:-1. Trapezium - quadrilateral 2. Trapezoid- shoe shaped.3. Capitate- largest carpal bone.4. Hamate- wedge-shaped.{Reference: Vishram Singh, pg no.33}", "cop": 1, "opa": "Capitate", "opb": "Hamate", "opc": "Pisiform", "opd": "Scaphoid", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "c7fda35b-af0a-4586-9f94-85095d2ecae7", "choice_type": "single"} {"question": "Opposition of thumb involves", "exp": "Opposition of thumb involves adduction, flexion & medial rotation at 1st carpo - metacarpal joint.", "cop": 3, "opa": "Pronation", "opb": "Supination", "opc": "Adduction", "opd": "Abduction", "subject_name": "Anatomy", "topic_name": null, "id": "b60e5b10-ed64-45d0-a9d8-60850db0da45", "choice_type": "single"} {"question": "Engagement of fetal head is with reference to", "exp": "Engagement is said to occur when the largest transverse diameter of fetal head crosses the pelvic inlet. Largest transverse diameter of fetal head is biparietal diameter", "cop": 1, "opa": "Biparietal diameter", "opb": "Bitemporal diameter", "opc": "Occipitofrontal diameter", "opd": "Suboccipitofrontal diameter", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "93db2573-592b-483c-a96c-fd970eb01843", "choice_type": "single"} {"question": "The inability to perceive the texture & shape an object occurs in lesion of.", "exp": "D. i.e. Nucleus cuneatus The middle pa of cuneate nucleus, the pars rotunds which receives impulses from digits, palm, dorsum of hand & forearm is specific for stereognosis.- Stereognosis is determination of texture & size of an object, is a function of cerebral coexThe sensory information of stereognosis to brain is carried by posterior column which includes tractus gracilis & tractus cuneatus Tractus gracilis bring sensation from lumber & sucral segments to nucleus gracilis (less specific for steriognosis)- Tractus cuneatus bring sensation from cervical & thoracic segments to nucleus cuneatus.Mnemonic - \"Gracilis for lower segments & Cuneatus for upper segments - G comes after C", "cop": 4, "opa": "Lateral spino-thalamic tract", "opb": "Nucleus gracils", "opc": "Spino reticular tract", "opd": "Nucleus cuneatus", "subject_name": "Anatomy", "topic_name": null, "id": "2d57a995-b025-40b0-87f4-dacd47bc6733", "choice_type": "single"} {"question": "hyponatremia is a side effect of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 955", "cop": 3, "opa": "olanzapine", "opb": "lithium", "opc": "carbamezepine", "opd": "clonazepam", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "92c70628-2996-4a3d-a31b-60ea4424f073", "choice_type": "single"} {"question": "Tectal breaking is seen in", "exp": "The normal tectum has a rounded or, sometimes, a squared appearance of the colliculi and a sho cranial-caudal length. In the Chiari II malformation, variable degrees of fusion of the colliculi and upward deflection of the tectum result in prominent beaking and elongation of the tectum.Arnold Chiari malformation consists of a downward displacement of the cerebellar tonsils through the foramen magnum resulting in obstructive hydrocephalus.Dandy-Walker malformation is characterized by agenesis or hypoplasia of the cerebellar vermis, cystic dilatation of the fouh ventricle, and enlargement of the posterior fossa.", "cop": 2, "opa": "Dandy - Walker malformation", "opb": "Arnold - Chiari malformation", "opc": "Aqueductal stenosis", "opd": "Third ventricular tumour", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "62f2e1a6-69a3-4024-a5af-7147468a5314", "choice_type": "single"} {"question": "Muscle of mastication are derived from", "exp": "First pharyngeal arch is also called mandibular archMUSCLES-Temporalis, Lateral pterygoid, Medial pterygoid, Masseter, Mylohyoid, Anterior belly of digastric, Tensor tympani, Tensor palatiSKELETAL ELEMENTS-Premaxilla,maxilla,zygomatic,temporal,Meckel&;s cailageLIGAMENTS-Anterior ligament of malleus, sphenomandibular ligamentNERVE-Mandibular nerveAERY-Maxillary aery", "cop": 1, "opa": "1st arch", "opb": "2nd arch", "opc": "3rd arch", "opd": "4th arch", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f6a907f1-30a9-4b8b-be52-6533a3531c56", "choice_type": "single"} {"question": "Climbing fiber inputs in the cerebellum stimulate", "exp": "Climbing fibers from contralateral inferior olive terminate on Purkinje cells, and also send a collateral innervation to the corresponding deep cerebellar nuclei RELAYS OF CEREBELLAR CIRCUIT Basket cells - Inhibits - Purkinje cell Stellate cells - Inhibits - Purkinje cell Climbing fibres - Stimulate - Purkinje cell Purkinje cells- Inhibits - Deep cerebellar nuclei Mossy fibres - Stimulate - Granule cells Granule cells - Stimulate - Stellate, basket, Purkinje, Golgi cells Golgi cells - Inhibitory - Interneuron NEURONS IN CEREBELLUM Granular cells > EXCITATORY NEURONS", "cop": 3, "opa": "Granule cells", "opb": "Golgi cells", "opc": "Purkinje cells", "opd": "Basket cells", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "21dca7a5-f4e1-4bfe-8a01-7e005b9aff93", "choice_type": "single"} {"question": "spina bifida is a complication of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential - CLEFT PALATE, FINGER NAIL HYPOLASIA, - SPINA BIFIDA Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 1, "opa": "carbamezepine", "opb": "clozapine", "opc": "lithium", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "c9d3e966-ccd8-4174-8504-5e83cf0b41cd", "choice_type": "single"} {"question": "Recurrent laryngeal nerve has close relation to", "exp": null, "cop": 3, "opa": "Superior thyroid artery", "opb": "Middle thyroid vein", "opc": "Inferior thyroid artery", "opd": "Inferior parathyroid", "subject_name": "Anatomy", "topic_name": null, "id": "0acfa35b-cd5b-4629-b53c-d530bbf1a201", "choice_type": "single"} {"question": "Drug of choice for night shift workers insomnia is", "exp": ".", "cop": 2, "opa": "Methylphenidate", "opb": "Modafinil", "opc": "Amitriptyline", "opd": "Adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "43646b6e-74f8-4910-ba0c-b77c4d44b7b9", "choice_type": "single"} {"question": "Lynch syndrome is associated with cancers of the", "exp": "Ref Harrison 17/e p575; Robbins 8/e p821- 822; 9/e p 810 Lynch syndrome is an autosomal dominant disorder it is called as hereditary non polyposis colon cancer It is caused because of defective DNA repair genes leading to micro satellite instability There is increased chances of multiple cancer such as colorectal cancer, endometrial,ovarian stomach, ureter, brain, small intestine,hepatobiliary tract, skin", "cop": 4, "opa": "Breast ,colon, ovary", "opb": "Breast , endometrium, ovary", "opc": "Breast ,colon,endometrium", "opd": "Colon,endometrium ,ovary", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "63cc582b-f4a0-41fb-956b-435a13a691d0", "choice_type": "single"} {"question": "Hypochloremia, hypokalemia and alkalosis are seen in", "exp": "Biochemical abnormality in congenital hyperophic pyloric stenosis is a regular feature of AIIMS and AI examinations it has been repeated several times. The biochemical abnormalities seen are: Hypokalemia Hypochloremia Alkalosis and Paradoxical aciduria Ref : Schwaz 9/e p59", "cop": 2, "opa": "Hirschsprung's disease", "opb": "Congenital hyperophic pyloric stenosis", "opc": "Esophageal atresia", "opd": "Jejunal atresia", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "5bb05983-c2d5-4fd4-bef5-907ec9b1c326", "choice_type": "single"} {"question": "The lateral mesoderm is divided into two distinct layers by the formation of the", "exp": "The lateral mesoderm is a subdivision of intraembryonic mesoderm and initially is a solid plate of mesoderm. The intraembryonic coelom forms in the middle of the lateral mesoderm, thereby dividing it into the intraembryonic somatic mesoderm and intraembryonic visceral mesoderm.", "cop": 2, "opa": "Extraembryonic coelom", "opb": "Intraembryonic coelom", "opc": "Cardiogenic region", "opd": "Notochord", "subject_name": "Anatomy", "topic_name": "General Embryology 2", "id": "2d3b54d4-989d-4933-9b51-6b79ee6ccabd", "choice_type": "single"} {"question": "Meralgia parasthetica is due to compression of", "exp": "Meralgia parasthetica is due to compression of Lateral cutaneous Nerve of thigh below inguinal ligament. It is a condition where pain and numbness is seen in Outer thigh.", "cop": 4, "opa": "Femoral Nerve", "opb": "Intermediate cutaneous Nerve of thigh", "opc": "Medial cutaneous Nerve of thigh", "opd": "Lateral cutaneous Nerve of thigh", "subject_name": "Anatomy", "topic_name": null, "id": "f831cb04-691a-43ac-a2e9-e7423ec9773d", "choice_type": "single"} {"question": "Azygous vein drains", "exp": "The azygous vein is formed by the confluence of the Lumbar azygous vein, Right ascending lumbar vein and right subcostal vein. It passes superiorly through the aoic apeure, posterior to the right diaphragmatic crus and anterior to the twelth veebral body. The azygos vein transpos deoxygenated blood from the posterior walls of the thorax and abdomen into the superior vena cava vein.", "cop": 1, "opa": "Into superior vena cava", "opb": "Anterior to costochondral junction", "opc": "Oesophagus", "opd": "Directly into right atrium", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cb94158b-a584-4dc8-b9db-85c8bf5a15b2", "choice_type": "single"} {"question": "Fibrous pericardium is attached to", "exp": "Fibrous pericardium base is broad and inseparably blended with the central tendon of the diaphragm.Ref: BD Chaurasia; Volume I; 6th Edition; Page no: 249", "cop": 1, "opa": "Central tendon", "opb": "Right crus", "opc": "Left crus", "opd": "Pleura", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "a9443a3a-c1ca-40a5-a175-5075439ccc0b", "choice_type": "single"} {"question": "Cesarean section is mandatory in following presentation", "exp": "In brow presentation, the engaging diameter is Mentoveical diameter which is 14 cms that cannot pass through cervix Hence,cesarean section is mandatory. Ref: Datta Obs 9e pg 368.", "cop": 4, "opa": "Cephalic", "opb": "Veex", "opc": "Face", "opd": "Brow", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "d66eb5d7-2918-4e89-bb4c-967f6b08eb99", "choice_type": "single"} {"question": "Third tubercle of femur provides attachment to", "exp": "The gluteal tuberosity gives attachment to pa of the Gluteus maximus: its upper pa is often elongated into a roughened crest, on which a more or less well-marked, rounded tubercle, the third trochanter, is occasionally developed. ref - Bdc vol2 6th ediiton p13", "cop": 1, "opa": "Gluteus maximus", "opb": "Gluteus medius", "opc": "Gluteus minimis", "opd": "Piriformis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7bd839b6-773d-45b7-ac5e-050da92fcf66", "choice_type": "single"} {"question": "Hepatocytes secrete", "exp": "Hepatocytes synthesize several plasma proteins, including Fibrinogen, Prothrombin, and Albumin", "cop": 4, "opa": "Glucagon", "opb": "Lysozyme", "opc": "Insulin", "opd": "Plasma proteins.", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "24c8d4ca-1fd6-41f4-b15c-1b7c5c1e4640", "choice_type": "single"} {"question": "Fracture of the spine of sphenoid results in", "exp": "Injury to the spine of sphenoid: Chorda tympani nerve is related on the medial side of the spine of the sphenoid, while auriculotemporal nerve is related to the lateral side. Chorda tympani gives secretomotor fibers to submandibular and sublingual salivary glands, whereas auriculotemporal gives secretomotor fibers to the parotid gland. So injury to the spine of sphenoid may injure both these nerves affecting the secretion of all three salivary glands.Ref: BD Chaurasia; Volume 3; 6th edition; Page no 298", "cop": 2, "opa": "Increased salivation", "opb": "Affects secretion of Submandibular, sublingual and Parotid glands", "opc": "Loss of general sensation on Anterior 2/3rd of tongue", "opd": "Affects only Parotid gland secretions", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "a46f65d3-748f-4cce-ac37-287bdd21c109", "choice_type": "single"} {"question": "Epithelium of \"Trigone of bladder\" is derived from", "exp": "The urinary bladder is derived from the cranial pa of the vesicourethral canal (endoderm).The epithelium of the trigone is derived from absorbed mesonephric ducts (mesoderm)Reference: Inderbir Singh Embryology; 10th edition; Page no: 292", "cop": 2, "opa": "Vesicourethral Canal", "opb": "Mesoderm", "opc": "Splanchnopleuric Mesoderm", "opd": "Urachus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5cd92a8b-7a7c-4e21-a300-1ff3b2bbb7be", "choice_type": "single"} {"question": "AFP is raised in", "exp": "Serum AFP levels are elevated In >70% of patients with HCC In 85-90% of patients with hepatoblastoma Ref : Sabiston 20th edition Pgno :1464", "cop": 2, "opa": "100% of hepatoblastoma", "opb": "90% of hepatoblastoma", "opc": "100% of HCC", "opd": "90% of HCC", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6d9c4062-8264-44bd-84f1-514f4554957f", "choice_type": "single"} {"question": "Froment's sign is due to", "exp": "Ans: A Ulnar nerve injury(Ref: Maheshwari 4h/e p. 65)Ulnar nerve injury:Adductor pollicis will be paralysed.Shows 'Froment's sign'or the'book test'.Procedure:The patient is asked to grasp a book between the thumb and index finger. Normally, a person will grasps book firmly with thumb extended, taking full advantage of adductor pollicis and the first dorsal interosseous muscles.Patient will hold the book by using the flexor pollicis longus (supplied by median nerve) in place of the inter-phalangeal joint of the thumb.This becomes more pronounced if the examiner tries to pull the book out while the patient tries to hold it.", "cop": 1, "opa": "Ulnar nerve injury", "opb": "Median nerve injury", "opc": "Radial nerve injury", "opd": "Intercostobrachial nerve injury", "subject_name": "Anatomy", "topic_name": null, "id": "2f512783-1eb0-40ee-b83a-a93f0ef052d8", "choice_type": "single"} {"question": "myocarditis is a side effect of", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients * Side effects * Agranulocytosis * Myocarditis * Seizure * Constipation * Weight gain * Metabolic syndrome Sialorrhea Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 2, "opa": "aripiprazole", "opb": "clozapine", "opc": "chlorpromazine", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "7b9f3f2d-3940-4fbd-8644-c935b1a8ce9a", "choice_type": "single"} {"question": "Painful arc syndrome is caused by the tear of", "exp": "Painful arc syndrome is caused by tear of the supraspinatus tendon. Subacromial bursitis, fracture of greater tuberosity also may produce Ref: Gray's39e/p-793-795", "cop": 2, "opa": "Deltoid", "opb": "Supra spinatus", "opc": "Trapezius", "opd": "Pectoralis major", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a838ceef-c560-45eb-97c7-d1390ecc7d90", "choice_type": "single"} {"question": "Highest point on skull", "exp": null, "cop": 4, "opa": "Pterion", "opb": "Porion", "opc": "Lambda", "opd": "Vertex", "subject_name": "Anatomy", "topic_name": null, "id": "3df1e0c0-3610-4f31-a8f1-4b0b9c01e964", "choice_type": "single"} {"question": "systematic desensitization was introduced by", "exp": "SYSTEMATIC DESENSITIZATION JOSEPH WOLPE Joseph Wolpe gave the concept of systematic desensitization This is a treatment used in phobia In phobia there is a conditioned fear response to aversive neutral stimulus and avoidance of that response leads to phobia Whenever there is a fear response there is stimulation of sympathetic system In that case stimulation of parasympathetic system by relaxation there is reduction in anxiety First step is to make a step ladder which are arranged based on the severity Then is go step by step and along with doing applied relaxation Slowly the the sympathetic system is reduced The patient will be able to approach stimulus without anxiety Ref. kaplon and sadock, synopsis of psychiatry, 11 th editio, pg no. 845", "cop": 2, "opa": "seligman", "opb": "joseph wolpe", "opc": "lorenz", "opd": "skinner", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "47632585-cfa0-428d-b9f1-f7667a860b29", "choice_type": "single"} {"question": "In the following nutrient aeries to bones, choose the wrong pair", "exp": "Nutrient aery to tibia is a branch of a posterior tibial aery Ref: Gray's 39e/p112-127", "cop": 4, "opa": "Humerus -profundabrachii", "opb": "Radius - anterior interosseous", "opc": "Fibula - peroneal", "opd": "Tibia - anterior tibial", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c9edafbb-d1f9-4113-96f5-1eae25262bdf", "choice_type": "single"} {"question": "Deep surface of hyoglossus is related to", "exp": null, "cop": 4, "opa": "Lingual nerve", "opb": "Hypoglossal Nerve", "opc": "Submandibular Ganglion", "opd": "Glossopharyngeal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "fd3dd950-a4e2-4a7c-bd5f-8ba683ee60a0", "choice_type": "single"} {"question": "A person having irresistible desire to do crime is", "exp": "Psychopath: psychopath is a person who is having irresistible desire to do crimes. He behaves in an anti social manner. He is otherwise called a sociopath. He can plan and implement his antisocial acts including murders in an efficient way. Punishment and advice have no effect on him. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 361", "cop": 4, "opa": "Fugue", "opb": "Amnesia", "opc": "Abreaction", "opd": "Psychopath", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "3e731201-8edf-4bad-881c-4695f89d0de2", "choice_type": "single"} {"question": "Length of male urethra", "exp": "The male urethra measures, on average, 18-20 cm in length. It commences at the internal urethral orifice in the trigone of the bladder and opens in the navicular fossa of the glans penis at the external urethral meatus, which is the narrowest pa of the urethra. ref - BDC vol2 pg376", "cop": 4, "opa": "3-5 cm", "opb": "5-10 cm", "opc": "10-15 cm", "opd": "15-20 cm", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "b8c0d45d-2912-408a-a28a-2cb7f1ff2ee2", "choice_type": "single"} {"question": "Blood platelets in stored blood do not remain functional after", "exp": "Platelet concentrates Volume :50ml Platelets are the only blood products which are stored at room temperature, 20-24 degC (Survival is 4-5 days) 1 unit of platelet increases the count by 5000-10000 The threshold for prophylactic platelet transfusion is 10000 /uL For invasive procedures, 50000/uL platelets is the usual target level Platelet count should be 1,00,000/uL before accepting the patient for surgery Transfused platelets generally survive for 2-7 days following transfusion ABO compatibility is desirable but not necessary Blood platelets in stored blood are non functional after 24 hours Ref: Harrison's 19th edition pgno: 953 Sabiston 20th edition pgno:588", "cop": 2, "opa": "12 hrs", "opb": "24 hrs", "opc": "48 hrs", "opd": "72 hrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "73c9f22a-8c2d-4c3b-90e1-6867891e0aaa", "choice_type": "single"} {"question": "Examination of a person accused of rape by medical practitioner comes under", "exp": "Sec53ACr.PC. Examination of person accused of rape by medical practitioner.- when a person is arrested on a charge of committing an offence of rape or attempt for rape, he shall be examined by a Govt registered medical practitioner and in the absence of such a practitioner within the radius of 16km from the place where the offence has been committed, by any other registered medical practitioner, at request of police officer not below the rank of sub inspector, using force reasonably necessary for that purpose. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 306", "cop": 3, "opa": "Sec 376CrPC", "opb": "Sec 45CrPC", "opc": "Sec53ACrPC", "opd": "Sec 54ACrPC", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "1e6f245b-e79c-49ff-99d9-d3fa51b30de4", "choice_type": "single"} {"question": "The technique of laparoscopic cholecystectomy was first described by", "exp": "History of Laparoscopic Cholecystectomy Dr. Ku Semm, the father of 'Pelviscopy', performed the first laparoscopic appendectomy in 1980 Eric Muhe performed the first laparoscopic cholecystectomy in 1982. He used a modified operating laparoscope placed at the umbilicus after establishing pneumoperitoneun In 1987, Phillip Mouret performed the first video laparoscopic cholecystectomy by using a camera attached to the laparoscope Ref: Blumga 5th edition Pgno :512", "cop": 1, "opa": "Eric Muhe", "opb": "Philip Moure", "opc": "Ku semm", "opd": "Eddie Reddick", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7ae763ce-fb83-4025-8834-2535363cfbce", "choice_type": "single"} {"question": "Hemotoxylin bodies seen in", "exp": "Ref Robbins 9/e p218 Systemic lupus erythematosus (SLE) is a multisystem auto- immune disease of protean manifestations and variable clinical behavior. Clinically, it is an unpredictable, remit- ting and relapsing disease of acute or insidious onset that may involve viually any organ in the body; however, it affects principally the skin, kidneys, serosal membranes, joints, and hea. Immunologically, the disease is associ- ated with an enormous array of autoantibodies, classically including antinuclear antibodies (ANAs). The clinical pre- sentation of SLE is so variable, with so many overlapping features with those of other autoimmune diseases (RA, polymyositis, and others), that it has been necessary to develop diagnostic criteria for SLE (Table 4-9). The diag- nosis is established by demonstration of four or more of the criteria during any interval of observation. Hematoxylin bodies are seen these are deposition of antigen antibody complexes in various tissues", "cop": 1, "opa": "SLE", "opb": "PAN", "opc": "Rheumatoid ahritis", "opd": "Wegener's granulomatosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "75163497-ec11-4a87-8381-4fbc3e90cba3", "choice_type": "single"} {"question": "Anterior choroidal aery is a branch of", "exp": "After piercing the dura mater forming the roof of the cavernous sinus, the internal carotid aery gives off three large branches. These are the following. (i) Ophthalmic aery (which supplies the orbit), and the (ii) Anterior and Middle cerebral aeries to the brain.It also gives off two smaller branches that take pa in supplying the brain: these are the (iv) Posterior communicating aery and the (v) Anterior choroidal aery.Ref: BD Chaurasia; volume 3; 6th edition; Page no: 384", "cop": 4, "opa": "Anterior cerebral aery", "opb": "Middle cerebral aery", "opc": "Posterior cerebral aery", "opd": "Internal carotid aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "4e8ec9f2-2804-4d6e-9832-bb48a63a647e", "choice_type": "single"} {"question": "Investigation of choice in early phase of renal transplant", "exp": "Ref - Bailey and love 25 e p1424", "cop": 4, "opa": "X ray", "opb": "IVP", "opc": "CT scan", "opd": "Ultrasonography", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "77a36394-246c-44d9-a696-c4584556e679", "choice_type": "single"} {"question": "Aoic opening is present at the veebral level of", "exp": "The aoic hiatus is a opening in the diaphragm. It is the lowest and most posterior of the large apeures. It is located approximately at the level of the twelfth thoracic veebra (T12). ref - semantischolar.org", "cop": 3, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "T11", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "78956bae-2c0d-4cd5-86a7-44dbfc6d00d1", "choice_type": "single"} {"question": "Pterygopalatine ganglion supplies", "exp": "Pterygopalatine is the largest parasympathetic peripheral ganglion. It serves as a relay station for secretomotor fibres to the lacrimal gland and to the mucous glands of the nose, the paranasal sinuses, the palate, and pharynx. Topographically, it is related to the maxillary nerve, but functionally it is connected to the facial nerve through its greater petrosal branch. The flattened ganglion lies in the pterygopalatine fossa just below the maxillary nerve, in front of the pterygoid canal and lateral to the Sphenopalatine foramen. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Parotid gland", "opb": "Submandibular gland", "opc": "Lacrimal gland", "opd": "Sublingual", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "5d153483-1980-40b8-80b7-ceb889dfaf37", "choice_type": "single"} {"question": "Illusions are a disorder of", "exp": "Read definitions of sensation, perception, Also know types of perceptual differences", "cop": 2, "opa": "Cognition", "opb": "Perception", "opc": "Emotion", "opd": "Eye", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "80b47d73-e8b8-414e-a844-b6adbfd003a7", "choice_type": "single"} {"question": "Hepatic vein drains into", "exp": "B. i.e. (Inferior vena-cava) (317- BDC-2 4th) (245- Snell 8th)The portal vein enters the liver and breaks up into sinusoids, from which blood passes into the hepatic veins that join the inferior vena cava.Tributaries of the Portal veinTributaries of Inferior vena-cava* Splenic vein* Inferior mesenteric vein* Superior mesenteric vein* Left gastric vein* Right gastric vein* Cystic vein1. Common iliac veins2. Third and fourth lumber veins3. Right testicular or ovarian vein4. Renal vein5. Right supra renal vein6. Hepatic veins** Inferior mesenteric vein is found in paraduodenal fossa", "cop": 2, "opa": "Portal vein", "opb": "Inferior vena cava", "opc": "Hemiazygos vein", "opd": "Abdominal aorta", "subject_name": "Anatomy", "topic_name": "Abdomen & Pelvis", "id": "90df358f-00c2-4648-b7fb-2c6ca3d9cce8", "choice_type": "single"} {"question": "Blow back phenomenon seen in", "exp": "Blow back phenomenon in hard contact: This is most frequently seen in gunshot wounds on the head where the hot expanding gases forced back between the scalp and skull are released by creating tears in the scalp. The margins will be eveed due to gases coming out under pressure. Sometimes, due to negative pressure tissue fragments may be drawn into the barrel and outside called black spatter. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 148", "cop": 1, "opa": "Hard contact entrance wound", "opb": "Light contact shot", "opc": "Close shot", "opd": "Intermediate shot", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "76c03df8-7867-4bf2-85d8-9c6cc93832b0", "choice_type": "single"} {"question": "Marker for B lymphocytes", "exp": "Ref immunology by Roitt 6/e p 29; 30; 19 ;9/e p191 CD 19,20,22 are main markers of human B cells .othersB cell markers are CD72 and CD78", "cop": 2, "opa": "CD34", "opb": "CD33", "opc": "CD19", "opd": "CD20", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b03ad257-1f14-4610-ad23-5b08d8a8ac61", "choice_type": "single"} {"question": "Thymus is developed from", "exp": null, "cop": 3, "opa": "4th arch", "opb": "2nd arch", "opc": "3rd arch", "opd": "6th arch", "subject_name": "Anatomy", "topic_name": null, "id": "0bcfd79a-60a5-480f-834b-f70fd96e6b3d", "choice_type": "single"} {"question": "Milk teeth total number in human being", "exp": "Milk teeth: Dental formula in children is 2,1,0,2. That is in one half of each jaw 2 incisors 1 canine 0 premolars 2 molars As there are 4 half's , 5x4= 20. There are 20 milk teeth. Ref : Ghai ,9th edition, chapter 2", "cop": 1, "opa": "20", "opb": "28", "opc": "32", "opd": "24", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6ec5e419-19e7-4b53-adf3-82af6d52bf1f", "choice_type": "single"} {"question": "Injury to long thoracic nerve leads to", "exp": "Injury to long thoracic nerve causes paralysis of serratus anterior muscle which clinically manifests as winging of scapula. The patient also finds difficulty in overhead abduction and touching the opposite shoulder. B D Chaurasia 7th edition Page no: 45", "cop": 1, "opa": "Winging of scapula", "opb": "Pointing index", "opc": "Claw hand", "opd": "Wrist drop", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "7dc712c5-5269-408a-8ed7-edbb3f8467d5", "choice_type": "single"} {"question": "Structure forming the Posterior 1/3 of veebral canal is (JIPMER May 2019)", "exp": "At tip of spine of veebra there is Supra-Spinous Ligament Inter-Spinous Ligament b/w two spines & Ligamentous Flavum - ligament connecting lamina of veebral arch superiorly to next adjacent veebra (gives elasticity to veebral canal) forming post 1/3rd of veebral canal.", "cop": 2, "opa": "Posterior Longitudinal Ligament", "opb": "Ligamentum Flavum", "opc": "Posterior 1/3 of Veebral Body", "opd": "Posterior 1/3 of Interveebral Disc", "subject_name": "Anatomy", "topic_name": "JIPMER 2019", "id": "7ba862e3-2159-4e66-9a58-1583eb85b47e", "choice_type": "single"} {"question": "Lateral cutaneous nerve of forearm is continuation of", "exp": "Lateral cutaneous nerve of forearm ( C5, C6 ) is the continuation of musculocutaneous nerve. It pierces deep fascia just lateral to the tendon of biceps 2-3 cm above the bend of the elbow, and supplies the skin of the lateral side of forearm, extending anteriorly to a small pa of the ball of the thumbs. B D Chaurasia 7th edition Page no: 79", "cop": 1, "opa": "Musculocutaneous nerve", "opb": "Ulnar nerve", "opc": "Radial nerve", "opd": "Median nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "8d156858-6cfb-45f6-a1d1-da0c71d517c6", "choice_type": "single"} {"question": "In the postnatal period the greatest growth in the grey matter of the C.N.S. is of", "exp": "The brain of newborn weighs approximately 300-350g. By 12 months, it reaches about two-thirds of adult brain. The postnatal growth of cerebral hemispheres results mainly from myelination. Myelination continues long after gray matter has reached a specific volume.", "cop": 3, "opa": "Length of Axon", "opb": "Neuron cell number", "opc": "Dendritic tree", "opd": "Size of Perikaryon", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "36b4dd98-08c2-4727-bf37-d19afbbde8aa", "choice_type": "single"} {"question": "Elastic cailages is found in", "exp": "Distribution of elastic cailage-it forms the &;skeletal &;basis of the auricle and of the lateral pa of the external acoustic meatusINDERBIR SINGH&;S TEXT BOOK OF HUMAN HISTOLOGY-reference,page no:85", "cop": 2, "opa": "Tracheal cailage", "opb": "Auricular cailage", "opc": "Aicular disc", "opd": "Bronchi", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "19462119-637b-4a50-9fc9-03bb4df2fc8a", "choice_type": "single"} {"question": "A patient comes with the H/O swelling in the submandibular region. He is diagnosed to have submandibular abscess. The incision to drain the abscess is put 1 cm below the base of the mandible because", "exp": null, "cop": 3, "opa": "The submandibular gland appears 1 cm below the mandible", "opb": "It is difficult to incise along the margin of the mandible", "opc": "The marginal mandibular nerve may be injured if incision is along the base of mandible", "opd": "To avoid injury to the cervical branch of facial nerve", "subject_name": "Anatomy", "topic_name": null, "id": "1e530a4f-853c-4ed8-9b97-ee1ad1bda243", "choice_type": "single"} {"question": "The classical lobule of the liver is centred around", "exp": "The \"classic\" liver lobule is the sixsided polyhedral prism with poal triads (hepatic aery, poal vein, and bile duct) at each of the corners. The vessels of the poal triads send distributing branches along the sides of the lobule, and these branches open into the sinusoids. The long axis of the lobule is transversed by the central vein, and this vessel receives blood from the sinusoids. Interconnecting sheets of hepatocytes are disposed in a radial pattern from the central vein to the perimeter of the lobule. Ref - pubmed.com", "cop": 3, "opa": "Postal vein", "opb": "Bile duct", "opc": "Central vein", "opd": "Hepatic aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f595d190-ba27-44d1-b3c1-ab5461e23142", "choice_type": "single"} {"question": "Nerves of pharyngeal cleft develop from", "exp": "Neural tube - upper pa: Brain CNS neural plate lower pa: Spinal cord ectoderm Neural crest - ganglia of PNS ARCH. NERVE MUSCLES SKELETON I. Main: CNV (III)Additional: chorda Tympani: (CNVII) Muscles of mastication (temporal, masseter & the pterygoids) ant. Belly of digastric, tensor palatini, tensor tympani. Premaxilla, maxilla, zygomatic, Mandible, malleus, incus, anterior, ligament of malleus, sphenomandibular ligament, meckel's cailage. II. Main: CN VII Additional: tympanic branch of glossopharyngeal nerve (CN IX) Muscles of facial expression, posterior belly of digastric, stylohyoid, stapedius Stapes, styloid process, stylohyoid ligament, lesser horn & upper poion of body of hyoid bone. III. CN IX - glossopharyngeal Stylopharyngeus Greater horn & lower pa of hyoid bone V-VI CNX - vagusSuperior laryngeal n - 4th arch Recurrent laryngeal n - 6th arch Cricothyroid, levator palatine, constrictors od pharynx intrinsic muscles of larynx Laryngeal cailage (thyroid, cricoid, arytenoid, corniculate, uniform) Nerves of pharyngeal arches : each arch has a main nerve derived from the neural plate and an additional nerve derived from NCC. The additional nerves are the nerves of pharyngeal clefts. (Derived from NCC) Fig. Each pharyngeal arch is supplied by its own cranial nerve. The trigeminal nerve supplying the first pharyngeal arch has three branches: the ophthalmic, maxillary, and mandibular. The nerve of the second arch is the facial nerve; that of the third is the glossopharyngeal nerve. The musculature of the fouh arch is supplied by the superior laryngeal branch of the vagus nerve, and that of the sixth arch, by the recurrent branch of the vagus nerve.", "cop": 2, "opa": "Neuroectoderm", "opb": "Neural crest cells", "opc": "Ectoderm", "opd": "Mesoderm", "subject_name": "Anatomy", "topic_name": "NEET 2018", "id": "08ebded1-96aa-4d19-a419-090b7f010f57", "choice_type": "single"} {"question": "Nutrient aery to fibula arises from", "exp": "Nutrient aery to fibula:- The peroneal aery gives off nutrient aery to fibula.Enters the bone on its posterior surface.Nutrient foramen directed downwards. {Reference: BDC 6E}", "cop": 1, "opa": "Peroneal aery", "opb": "Anterior- tibial aery", "opc": "Posterior tibial aery", "opd": "Popliteal aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d1e4f345-cd9e-4a3f-8b37-3cfd44c75c43", "choice_type": "single"} {"question": "Not seen in carpal tunnel syndrome", "exp": "Carpal tunnel syndrome is compression of medial nerve below flexor retinacalum. Palmar cutaneous branch is given before median nerve pierces below flexor retinacalum and hence no loss of sensation on lateral 3⅓ of palm.", "cop": 4, "opa": "Pain of medial 3 fingers", "opb": "Ape thumb deformity", "opc": "Symptoms worsen at night", "opd": "Sensory loss on lateral 3½ of palm", "subject_name": "Anatomy", "topic_name": null, "id": "e4ae1105-f44a-42f4-b2a7-b34341cfedd8", "choice_type": "single"} {"question": "Substantia gelatinosa corresponds to", "exp": "The Rexed laminae comprise a system of ten layers of grey matter (I-X), identified in the early 1950s by Bror Rexed to label poions of the grey columns of the spinal cord NOTE: Lamina I: posteromarginal nucleus Lamina II: substantial gelatinosa of Rolando Laminae III and IV: nucleus proprius Lamina V& VI: base of the dorsal horn. Lamina VII: intermediomedial nucleus, intermediolateral nucleus, nucleus dorsalis Lamina VIII & IX: medial and lateral groups of nuclei of anterior grey column Lamina X: Central Zone, grey matter surrounding the central canal ref - vishram singh neuroanatomy 2e pg59", "cop": 2, "opa": "Rexed laminae I", "opb": "Rexed laminae II", "opc": "Rexed laminae III", "opd": "Rexed laminae IV", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "f5306b03-fb29-4406-92d9-0e28b717f3bc", "choice_type": "single"} {"question": "In high risk population , HCC is best detected by", "exp": "Diagnosis Focal lesion 1-2 cm: Two imaging techniques with aerial hypervascularization and venous wash out Focal lesion> 2cm: One imaging technique with aerial hypervascularization and venous washout Techniques to be considered : Dynamic CT and MRI Screening is based on regular ultrasound scanning in high risk population Biopsy proof of HCC is not required Ref: Sabiston 20th edition 1458-1463", "cop": 1, "opa": "USG", "opb": "CT", "opc": "MRI", "opd": "PET scan", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1ba6d92d-40ed-4ede-ae33-07724bb2a75f", "choice_type": "single"} {"question": "A person suffered a fracture of neck of fibula followed by foot drop. The involved nerve is", "exp": "Common peroneal nerve is in close relation to Neck of fibula and on damage leads to foot drop.", "cop": 1, "opa": "Common peroneal nerve", "opb": "Tibial nerve", "opc": "Deep peroneal nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": null, "id": "c8d140cf-c954-46fb-a023-3d9e6c70351b", "choice_type": "single"} {"question": "Cords of Billroth in spleen are found in", "exp": "75% of spleen is red pulp, predominantly having RBCs. 25% of spleen is white pulp, predominantly having WBCs Red pulp contains sinusoids which are filled with RBCs & blood and splenic cords of billroth White pulp contains lymphoid follicles &periaerial lymphatic sheath.", "cop": 3, "opa": "Mantle zone", "opb": "Trabecular zone", "opc": "Red pulp", "opd": "White pulp", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "8642ab5b-0b7f-47e2-aba4-fa2a448a5cf3", "choice_type": "single"} {"question": "Denver's shunt is used in", "exp": "A peritoneal-venous shunt (also called Denver shunt) is a shunt which drains peritoneal fluid from the peritoneum into veins, usually the internal jugular vein or the superior vena cava. It is sometimes used in patients with refractory ascites. It is a long tube with a non-return valve running subcutaneously from the peritoneum to the internal jugular vein in the neck, which flows ascitic fluid to pass directly into the systemic circulatio Ref Bailey and love 27 e Liver", "cop": 1, "opa": "Ascites", "opb": "Raised ICP", "opc": "Headache", "opd": "Dialysis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8c2d14a1-29c5-4d9b-b495-0b44d085c3c1", "choice_type": "single"} {"question": "In case of occlusion occurs at the 2nd pa of Axillary aery, blood flow is maintained by collateral/ anastomosis between", "exp": "Ligation, thrombosis or trauma of axillary aery anywhere between origins of thyrocervical trunk &subscapular aeries will not lead to compromise of distal arm flow.", "cop": 3, "opa": "Anterior and posterior circumflex humor and aery", "opb": "Supra scapular and posterior circumflex aery", "opc": "Deep branch of the transverse cervical aery and sub scapular aery", "opd": "Anterior circumflex aery and sub scapular aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "83c95e4a-1ea1-4128-8ad6-5939d4e8d261", "choice_type": "single"} {"question": "Lining of common bile duct", "exp": "Common bile duct is lined by simple columnar epithelium , simple cuboidal epithelium at it's proximal region. Ref: IB Singh textbook of histology 6e pg 268.", "cop": 1, "opa": "Simple columnar", "opb": "Ciliated columnar", "opc": "Pseudo stratified squamous", "opd": "Transitional", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "615be929-ba70-460e-ada6-f5b4f4d7fd32", "choice_type": "single"} {"question": "Cranial nerve not carrying parasympathetic fibers", "exp": "Ans. is 'a' i.e. Fourth Four cranial nerves CN III, CN VII, CNIX & CN X carry presynaptic parasympathetic (visceral motor) axons as they emerge from brain stem.Parasympathetic fibres carrying cranial nervesAssociated GanglionOcculomotor (III)Ciliary ganglionFacial (VII)Pterygopalatine & Submandibular ganglionGlossopharyngeal (IX)Otic ganglionVagus (X)Visceral ganglionsAlso know:Pure motorPure sensory (unique/special sensation carrying)MixedOcculomtor (III)Trochlear (IV)Abducent (VI)Spinal accessory (XI)Hypoglossal (XII)Olfactory (I)Optic (II)Vestibulocochlear VIII)Trigeminal (V)Facial (VII)Glossopharyngeal (IX)Vagus (X)Olfactory nerve (CNI) is the only sensory cranial nerve that projects directly to the cerebral cortexOptic nerve terminates in the thalamus while the other ten pairs of C.N. are attached to brain stem.Except the vagus N., all the cranial nerves are confined to head & neck.Trochlear N. is the only cranial nerve to emerge from the dorsal surface of the brain stem.Trochlear N. is the smallest cranial nerve in terms of axons it contains. It supplies only one muscle - the superior oblique.Trochlear N. has the longest intracranial course.", "cop": 1, "opa": "Fourth", "opb": "Seventh", "opc": "Third", "opd": "Ninth", "subject_name": "Anatomy", "topic_name": "Cranial Cavity", "id": "1f57b242-223e-441d-aab5-5b8d570db16d", "choice_type": "single"} {"question": "Erb’s palsv involves", "exp": "ERB’S PARALYSIS\n\n One region of upper trunk (C# Cf Q of the brachial plexus is called Erb's point where six nerves meet,\n Injury at this point results in Erb’s paralysis.\n The injury is due to undue separation of the head from the shoulder; which may be seen in: - i. Birth injury ii. Fall on the shoulder iii. During Anesthesia Clinical features of Erb’s palsv A.\n\nMuscles paralysed: Mainly biceps brachii Q , deltoid, branchialis and brachioradialis. Partly supraspinatus Q , infraspinatus Q and supinator.\nB. Deformity (position of the limb) i. Arm : Hanges by the side; it is adducted and medially rotated Q ii. Forearm : Extended and pronated 0\nThe deformity is known as “policeman's tip hand’ or ‘porter’s tip hand’. C. Disability : The following movements are lost. o Abduction Q and lateral rotation of the arm (shoulder) Q ,\n\n Flexion and supination of the forearmQ , \n Biceps and supinator jerks are lost.\n Sensations are lost over a small area over the lower part of the deltoid. KLUMPKE’S PARALYSIS\n Site of injury : Lower trunk of the brachial plexus Q \nCause of injury:\n\nUndue abduction of the arm, as in clutching something with the hands after a fall from a height, or sometimes in birth injury,\n\n Nerve roots involved : - Mainly T1 and partly C8.\n Muscles paralysed i. Intrinsic muscles of the hand (T1). ii. Ulnar flexors of the wrist and fingers (C8) iii.\n\nDeformity (position of the hand). Claw hand due to the unopposed action of the long flexors and extensors of the fingers.\nIn a claw hand there is hyperextension at the metacarpophalangeal joints and flexion at the interphalangeal joints.\nDisability i. Claw hand ii. Cutaneous anaesthesia and analgesia in a narrow' zone along the ulnar border of the forearm and hand.\niii. Homer’s syndrome if T1 is injured proximal to white ramus communicans to first thoracic sympathetic ganglion.\nThere is ptosis, miosis, anhydrosis, enophthalmos, and loss of ciliospinal reflex-may be associated.\n(This is because of injury to sympathetic fibres to the head and neck that leave the spinal cord through nerve T1). iv. Vasomotor changes :\nThe skin area with sensory loss is warmer due to arteriolar dilation. It is also drier due to the absence of sweating as there is loss of sympathetic activity.\nv. Trophic changes : Long standing case of paralysis leads to dry and scaly skin. The nails crack easily with atrophy of the pulp of fingers.", "cop": 1, "opa": "C5C6", "opb": "C8T1", "opc": "T1T2", "opd": "C 6C7", "subject_name": "Anatomy", "topic_name": null, "id": "e4c9ea13-043e-4c19-97cb-79a7424c0282", "choice_type": "single"} {"question": "The clot formed after coagulation cascade is not stable unless extensive cross linking occurs .this is done by", "exp": "Ref Robbins 9/e p119 Thrombin is the principal enzyme of hemostasis. It catalyzes the conversion of fibrinogen to fibrin and activates procoagulant factors V, VIII, XI, and XIII. Additionally, when bound to thrombomodulin, it activates protein C, an anticoagulant zymogen", "cop": 2, "opa": "Plasmin", "opb": "Thrombin", "opc": "Factor 8", "opd": "High molecular weight kininogen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7eab7eab-2cd0-4633-bce5-1a2cf0c4c311", "choice_type": "single"} {"question": "Most common site of pheochromocytoma after adrenal gland is", "exp": "Refer Robbins page no 1134 hormone-secreting tumour that can occur in the adrenal glands. Phaeochromocytomas usually develop in the small glands on top of the kidneys (adrenal glands). They most commonly affect people between the ages of 20 and 50, but can occur at any age.", "cop": 2, "opa": "Hilum of kidney", "opb": "Organs of Zuckerkandl", "opc": "Neck", "opd": "Urinary bladder", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "b9bbc96f-7781-497a-8d03-4b3d54d2f811", "choice_type": "single"} {"question": "Local anesthetics act by", "exp": ".", "cop": 4, "opa": "Forming area of nerve block along a neuron", "opb": "Binding to calcium receptor on nerve membrane", "opc": "Blocking calcium channels of nerve membrane", "opd": "Inhibiting the sodium pump", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c9b92eb4-c432-43ca-868e-028796d8ff9e", "choice_type": "single"} {"question": "Risk of malignancy in BIRADS score 2 is", "exp": "BIRADS score - Breast Imaging Repoing and Data System Category 2- Negative, routine mammogram in 1 year is recommended", "cop": 1, "opa": "0-2%", "opb": "2-4%", "opc": "10%", "opd": "50%", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "cdaa43d7-1239-4b57-8f57-6e8afb8be02d", "choice_type": "single"} {"question": "The trapezoid body is concerned with", "exp": "Trapezoid body is a trapezium-shaped mass of white matter lying in the anterior pa of tegmentum, posterior to basilar pa of pons.It is formed by decussation of transversely running fibres arising from cochlear nuclei of both sides before it reaches the superior olivary nucleus. This decussation is believed to help in localization of sound.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 80)", "cop": 2, "opa": "Pain and temperature", "opb": "Hearing", "opc": "Touch and pressure", "opd": "Proprioception", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "a981c626-eca9-48f2-a96e-0cb2c0df3125", "choice_type": "single"} {"question": "Scheuerman\"s disease occurs in", "exp": "Scheuermann deformity is the osteochindritis of ring epiphysis of veebrae. REF : MAHESWARI 9TH ED", "cop": 4, "opa": "Adults", "opb": "Elderly", "opc": "infants", "opd": "Adolescents", "subject_name": "Anatomy", "topic_name": null, "id": "c0786090-62b8-44a3-92b4-3ebb51ec3bd3", "choice_type": "single"} {"question": "Tumour arising from Rathke's pouch is", "exp": "Rathke's pouch develop at the roof of oral cavity from surface ectoderm to form most of pituitary . Posterior pituitary develops from diencephalon. Craniopharyngioma is a tumor that develop in the sella turcica.", "cop": 3, "opa": "Meningioma", "opb": "Glioma", "opc": "Craniopharyngioma", "opd": "Ependymoma", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "7d86d506-ac4d-4d4d-8019-f3ca69582d42", "choice_type": "single"} {"question": "Esophageal opening in diaphragm is at the level of", "exp": "Oesophagus pierces diaphragm at level of tenth thoracic veebrae. BD CHAURASIA&;S HUMAN ANATOMY VOLUME 1. 6TH EDITION Page no- 282", "cop": 2, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "T6", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "629b5d24-64c1-4f29-8ce8-f03ac7d38b97", "choice_type": "single"} {"question": "Appendicular aery is a branch of", "exp": "The appendicular aery is a terminal branch of the ileocolic aery that descends behind the termination of the ileum and enters the mesoappendix of the vermiform appendix. It runs near the free margin of the mesoappendix and ends in branches which supply the appendix. ref - sciencedirect.com", "cop": 1, "opa": "Iliocolic", "opb": "Right colic", "opc": "Inferior mesenteric", "opd": "Marginal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "36077f47-1438-41a5-bc2a-72ebcae1084d", "choice_type": "single"} {"question": "Compartment involved in Dequervian's tenosynovitis", "exp": "Extensor pollicis brevis and abductor pollicis longus are invovled in Dequervian's tenosynovitis.\nThe condition is tested using FRINKELSTEIN test.", "cop": 1, "opa": "I", "opb": "II", "opc": "V", "opd": "VI", "subject_name": "Anatomy", "topic_name": null, "id": "abf3fa24-516d-4b45-8dbd-c23ec77aa512", "choice_type": "single"} {"question": "Water lilly appearance in a chest radiograph suggests", "exp": ".", "cop": 4, "opa": "Metastases", "opb": "Cavitating metastasis", "opc": "Aspergilloma", "opd": "Ruptured hydatid cyst", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c7bd854c-05eb-491a-959f-ab01bd6b2adb", "choice_type": "single"} {"question": "Modiolus is directed", "exp": "The bony cochlea resembles the shell of a common snail. It forms the anterior pa of the labyrinth. It has a conical central axis known as the modiolus around which the cochlear canal makes two and three quaer turns. The modiolus is directed forwards ( anteriorly ) and laterally.", "cop": 1, "opa": "Anterolateral-inferior", "opb": "Anterolateral-superior", "opc": "Posteromedial-inferior", "opd": "Posteromedial-superior", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "2d2c24cd-7733-4c86-9c45-257df40710cb", "choice_type": "single"} {"question": "Wear and tear pigment in the body refer to", "exp": "Refer ribbons 7/e p39 , 9/e p64", "cop": 1, "opa": "A. LiPochrome", "opb": "B. Melanin", "opc": "C. Anthracotic pigment", "opd": "D. Haemosiderin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0de7f38d-f0aa-45fd-a960-e5d1d8de2a9a", "choice_type": "single"} {"question": "Common carotid artery divides at the level of", "exp": "Ans. is 'c' i.e. Superior border of thyroid cartilage Common carotid artery ends at the level of upper border of the thyroid cartilage by dividing into external & internal carotid arteries Also remember the following imp. levels * Sternal angle- costal cartilage of 2nd rib, T4/T5IV disc* Xiphoid process- T9* Tracheal bifurcation- T4/T5 IV disc* Trachea extends from- C6 to T5* Arch of aorta begins and ends at- T4* Aortic opening in diaphragm- T12* Esophageal opening in diaphragm- T10* Vena caval opening in diaphragm- T8* Thoracic duct crosses from Rt to Left- T5* Splenic axis- 10th rib* Celiac trunk arises- T12/L, IV disc* Superior mesenteric artery arises- LI* Renal arteries- L1/L2* Inferior mesenteric artery- L3* Aorta ends by bifurcating into common iliac arteries- L4* IVC begins at- L5* Umbilicus- L3/L4", "cop": 3, "opa": "Hyoid bone", "opb": "Cricoid cartilage", "opc": "Superior border of thyroid cartilage", "opd": "Inferior border of thyroid cartilage", "subject_name": "Anatomy", "topic_name": "Triangles of Neck", "id": "7a930f17-8810-4fad-ac18-04e8d747e063", "choice_type": "single"} {"question": "Spinal cord develops from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:325Spinal cordThe spinal cord is developed from the coudal cylindrical pa of the neural tube. when this pa of the neural tube is formed, its cavity its cavity is in the form of a dorsal ventricular cleft", "cop": 1, "opa": "Neural tube", "opb": "Mesencephalon", "opc": "Rhombencephalon", "opd": "Prosencephalon", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4874e184-de14-4083-89dc-d2ae5a03cf53", "choice_type": "single"} {"question": "Left sided poal hypeension is best treated by", "exp": "Left sided poal hypeension Poal hypeension due to isolated splenic vein thrombosis is known as left sided poal hypeension or sinistral hypeension Pressure in poal vein and SMV are normal There is gastrosplenic venous hypeension leading to formation of gastric varices Causes Pancreatitis (most common) leading to splenic vein thrombosis Neoplasm Trauma Treatment Splenectomy is the treatment of choice Ref: Sabiston 20th edition Pgno : 1436-1437", "cop": 1, "opa": "Splenectomy", "opb": "Poocaval shunt", "opc": "Lino-renal ligament", "opd": "Spleno-renal shunt", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "994bcd59-0574-4a88-a04e-636c3055248e", "choice_type": "single"} {"question": "Heerfordt's syndrome cosists of fever , parotid enlargement facial palsy", "exp": "Ref Harrison 18/e p2806 Lofgren's syndrome consists of erythema nodosum, hilar adenopathy on chest x-ray and uveitis Heerfordt's syndrome .: Fever , parotid enlargement , facial palsy , uveitis", "cop": 4, "opa": "Ahralgia", "opb": "Bilateral hilar adenopathy", "opc": "Erythema nodosum", "opd": "Anterior uveitis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "daf7f74b-64fb-43d2-9c07-911fe27e52d6", "choice_type": "single"} {"question": "This permanent tooth is", "exp": "First molar is the first permanent tooth to appear, 6-7 yrs", "cop": 3, "opa": "Lower medial incisor", "opb": "Upper medial incisor", "opc": "First molar", "opd": "First premolar", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9f00da6d-1738-4d1a-9aa7-5fd93feed994", "choice_type": "single"} {"question": "Tympanic branch of the middle ear is derived from", "exp": "NERVE SUPPLY OF MIDDLE EAR: The tympanic branch of the glossopharyngeal nerve. Its fibres are distributed to the mucous membrane of the middle ear, the auditory tube, the mastoid antrum and air cells.It also gives off the lesser petrosal nerve. The superior and inferior coicotympanic nerves arise from the sympathetic plexus around the internal carotid aery. These fibes are vasomotor to the mucous membrane. Ref BDC volume 3,sixth edition pg 281", "cop": 2, "opa": "Facial nerve", "opb": "Glossopharyngeal nerve", "opc": "Nerve to stapedius", "opd": "Chorda tympani", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d4b1cbf0-b404-4f75-b7a9-cecdb2824916", "choice_type": "single"} {"question": "Approximate distance of diphragmatic constriction from nostril & incisor are", "exp": "C i.e. 17\" & 16\"", "cop": 3, "opa": "7\" & 6\"", "opb": "11' & 10\"", "opc": "17\" & 16\"", "opd": "23\" & 22\"", "subject_name": "Anatomy", "topic_name": null, "id": "7d53a9d8-e6a4-4143-9b0e-2a50505efb2a", "choice_type": "single"} {"question": "Structures at Angle of Louis", "exp": "Sternal angle/Louis angle:It is felt as a transverse ridge about 5cm below the suprasternal notch.It marks the manubriosternal joint and lies at the level of the second costal cailage anteriorly and the disc between the fouh and fifth thoracic veebrae posteriorly.This is an impoant landmark for many reasons.The arch of aoa begins and also ends at this level. BD CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX SIXTH EDITION VOLUME 1.PAGE NO187", "cop": 1, "opa": "Arch of aoa", "opb": "Azygous vein", "opc": "Common carotid aery", "opd": "Clavicle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "8710e2b8-263c-43a1-b9d8-f3425182f7dc", "choice_type": "single"} {"question": "Histamine causes", "exp": "ref Robbins 7/e p64;9/e p73 As pa of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.", "cop": 3, "opa": "Hypeension", "opb": "Vasoconstriction", "opc": "Vasodilation", "opd": "Tachycardia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "92cd14de-c85a-4cb7-b0ad-dbdeebae6b39", "choice_type": "single"} {"question": "Resistance to Zidovudine develops due to", "exp": "Zidovudine is a nucleoside reverse transcriptase inhibitors which is a viral enzyme .HIV undergoes mutations in this enzyme to become resistant to NIs Refer :KDT 6/e p770", "cop": 1, "opa": "Mutation at reverse transcriptase", "opb": "Increased efflux of the drug from inside the cell", "opc": "Increased metabolism of drug", "opd": "Decreased Zidovudine 5 triphosphate formation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "98186f26-5a51-405c-a337-60fcaa26d8a1", "choice_type": "single"} {"question": "Antiglaucoma drug used to increase uveoscleral outflow is", "exp": "(Refer: Parson's, 21stedition, pg no: 154,155)", "cop": 3, "opa": "Acetazolamide", "opb": "Pilocarpine", "opc": "Latanoprost", "opd": "Timolol", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "09b91448-fa8b-4114-bde3-359826c69557", "choice_type": "single"} {"question": "Central dot is seen in", "exp": "Caroli's disease Clinical features Symptoms include cholangitis (64%), poal hypeension (22%), and abdominal pain (18%) More common in males Septa containing poal veins protrude into the lumen of the ecstatic bile ducts (central dot sign) The main and often the only symptom of bacterial cholangitis secondary to caroli's disease is fever without abdominal pain and jaundice Frequent episodes of cholangitis indicates poor prognosis Most stones are pigmented in caroli's disease Ref: Sabiston 20th edition Pgno :1511", "cop": 3, "opa": "Primary sclerosing cholangitis", "opb": "Liver hamaoma", "opc": "Caroli's disease", "opd": "Polycystic liver disease", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "20657323-21b4-4699-b9db-7e7c70337ca2", "choice_type": "single"} {"question": "Wide fixed split S2 occurs in", "exp": "Ref Harrison 19 th ed pg 1447 Fixed splitting of S2 , in which the A2 -P2 interval is wide and does not change during the respiratory cycle, occurs in patients with a secundum atrial septal defect.", "cop": 3, "opa": "VSD", "opb": "Mitral stenosis", "opc": "ASD", "opd": "Coarctation of aoa", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8d4b28de-ea69-4ef8-8d8c-16709af5f861", "choice_type": "single"} {"question": "Ultra structure finding of irreversible injury", "exp": "Amorphous densities in mitochondria Ref , Robbins 7/e p41-2 ,9/ep42", "cop": 2, "opa": "Ribosomal detachment from endoplasmic reticulum", "opb": "Amorphous densities in mitochondria", "opc": "Formation of phagolysosomes", "opd": "Cell swelling", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9f11e268-f221-40a7-877c-6d7bf873aa66", "choice_type": "single"} {"question": "Elimination after 3 half lives in first order kinetics is", "exp": "Cp - > Cp/2 in 1 half-life i.e. 50.0 % lost 50.0 % Cp - > Cp/4 in 2 half-lives i.e. 25.0 % lost 75.0 % Cp - > Cp/8 in 3 half-lives i.e. 12.5 % lost 87.5 % Cp - > Cp/16 in 4 half-lives i.e. 6.25 % lost 93.75 % Cp - > Cp/32 in 5 half-lives i.e. 3.125 % lost 96.875 % Cp - > Cp/64 in 6 half-lives i.e. 1.563 % lost 98.438 % Cp - > Cp/128 in 7 half-lives i.e. 0.781 % lost 99.219 % Ref-KDT 7/e p30", "cop": 3, "opa": "12.50%", "opb": "75%", "opc": "87.50%", "opd": "94%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "08667805-05df-43e7-82dd-3bc9cff38e7d", "choice_type": "single"} {"question": "antipsychotic drug approved for the managemnt of parkinsonian patients", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients * Side effects * Agranulocytosis * Myocarditis * Seizure * Constipation * Weight gain * Metabolic syndrome Sialorrhea ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 1, "opa": "clozapine", "opb": "olanzapine", "opc": "haloperidol", "opd": "risperidone", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "d63934b3-4b1f-47db-96ff-316ac511605d", "choice_type": "single"} {"question": "The inferior most structure of right hilum is", "exp": "The inferior most structure of right hilum is inferior pulmonary vein. The sequence of structures at the right hilum superior to inferior is: Superior lobar (epaerial) bronchus. Pulmonary aery Principal bronchus Inferior pulmonary vein Ref: Gray&;s Anatomy 41st edition Pgno: 958", "cop": 2, "opa": "Right atrium", "opb": "Inferior pulmonary vein", "opc": "Pulmonary aery", "opd": "Inferior bronchial vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "964c949c-afff-4c27-b102-534c0f590141", "choice_type": "single"} {"question": "In multiparous women, sho labor is defined as a rate of cervical dilatation of", "exp": "Sho labors were defined as a rate of cervical dilatation of 5 cm/hr or faster for nulliparas and 10cm/hr for multiparas. Such sho labors were more common in multiparas who typically had contractions at intervals less than 2 minutes and were associated with placental abruption, meconium, postpaum hemorrhage, cocaine abuse, and low Apgar scores.Precipitous labor terminates in the expulsion of the fetus in < 3 hours.Ref: William&;s obstetrics; 24th edition; Chapter: 23", "cop": 4, "opa": "3cm/hr", "opb": "5cm/hr", "opc": "8cm/hr", "opd": "10cm/hr", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ceaa63db-dcf3-4ffa-ac22-292acc2950a3", "choice_type": "single"} {"question": "Nerve supply of the papillary muscle, the sphincter papillae is done through", "exp": "The ciliary ganglion is a peripheral parasympathetic ganglion topographically connected with the nasociliary nerve from ophthalmic division of trigeminal nerve but functionally connected to the oculomotor nerve.The motor or parasympathetic root of the ciliary ganglion is derived from nerve to inferior oblique and consists of preganglionic parasympathetic fibres from the Edinger-Westphal nucleus. These fibres relay in the ganglion. The postganglionic parasympathetic fibers arise from the cells of the ganglion and pass through sho ciliry nerves to supply the ciliary muscle and sphincter pupillae.The branches of the ciliary ganglion are sho ciliary nerves that contain fibres from all 3 roots, run above and below the optic nerve towards the eyeball. On reaching the eyeball, they pierce the sclera around the attachment of the optic nerve and pass forwards in the space between the sclera and the choroid to reach the target organs.The ciliary ganglion is blocked to produce dilatation of the pupil before cataract extraction.Reference: Textbook of anatomy, Head neck, and brain, Vishram Singh, 2nd edition, page no.298", "cop": 1, "opa": "Third cranial nerve", "opb": "Fouh cranial nerve", "opc": "Sixth cranial nerve", "opd": "Seventh cranial nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "be51a65d-aa26-462c-a95a-ae381b5a1522", "choice_type": "single"} {"question": "Structure piercing investing layer of deep cervical fascia in posterior triangle of neck", "exp": "Investing layer in the posterior triangle of neck is pierced by: * External jugular vein * Supraclavicular nerves. * Cutaneous nerves including lymphatics.", "cop": 4, "opa": "Spinal accessory nerve", "opb": "Common carotid aery", "opc": "Internal jugular vein", "opd": "External jugular vein", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "1b660440-15a0-4381-a045-0042d692d283", "choice_type": "single"} {"question": "Muscle attached to lateral surface of greater trochanter", "exp": "GREATER TROCHANTER:- Quadrangular prominence located on upper pa of the junction of neck with the shaft.Attachments:-1. Apex-pyriformis 2. Anterior surface-gluteus minimus3. Medial surface- obturator internus and two gamelli.4. Trochanteric fossa- obturator externus.5. Lateral surface-gluteus medius. {Reference: BDC 6E pg no. 16}", "cop": 2, "opa": "Gluteus maximus", "opb": "Gluteus medius", "opc": "Gluteus minimus", "opd": "Piriformis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "3b2cd3ab-2ed2-4939-95d0-d4b8d69f08b7", "choice_type": "single"} {"question": "The weight of the upper limb is transmitted to the axial skeleton by", "exp": "The weight of the upper limb is transmitted to the axial skeleton by Costoclavicular ligament The weight of the upper limb is transmitted as follows: Upper limb to Coracoclavicular ligament to Clavicle to Costoclavicular ligament to Axial skeleton. Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41e pg 800,809.", "cop": 1, "opa": "Costoclavicular ligament", "opb": "Coracoacromial ligament", "opc": "Coracoclavicular ligament", "opd": "Coracohumeral ligament", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "3b521885-90a7-48d0-88b2-6a3c43028e41", "choice_type": "single"} {"question": "HE R2/neu receptor plays a role in", "exp": "Ref Robbins 8/e p1090,9/e p1062 The ErbB family consists of four plasma membrane-bound receptor tyrosine kinases. One of which is erbB-2, and the other members being epidermal growth factor receptor, erbB-3 (neuregulin-binding; lacks kinase domain), and erbB-4. All four contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular domain that can interact with a multitude of signaling molecules and exhibit both ligand-dependent and ligand-independent activity. Notably, no ligands for HER2 have yet been identified. HER2 can heterodimerise with any of the other three receptors and is considered to be the preferred dimerisation paner of the other ErbB receptors. Dimerisation results in the autophosphorylation of tyrosine residues within the cytoplasmic domain of the receptors and initiates a variety of signaling pathway", "cop": 1, "opa": "Predicting therapeutic response", "opb": "Diagnosis of breast cancer", "opc": "Screening of breast cancer", "opd": "Recurrence of tumor", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "01cc94b9-3691-4219-bbda-af4bf961fd5c", "choice_type": "single"} {"question": "Commonest malignant bone tumor is", "exp": "Refer Robbins page no 8th 609-611 Multiple also called as Kahlers disease", "cop": 1, "opa": "Multiple myeloma", "opb": "Osteosarcoma", "opc": "Ewings sarcoma", "opd": "Giant cell tumor", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "0be3d9b5-8d52-4b64-b4da-069a1a1d2111", "choice_type": "single"} {"question": "The hard palate contains", "exp": "The hard palate contains keratinized stratified squamous epithelium, has a submucosa, and contains minor salivary gland. The bony structure of the hard palate is covered by a firmly attached mucosa in the central pa. In the lateral pas, the hard palate also has a submucosal layer containing blood vessels. There are minor mucous type salivary glands in the submucosa in the posterior pa of the hard palate. Ref: Gray&;s Anatomy 41st edition Pgno: 510", "cop": 1, "opa": "Keratinized epithelium, submucosa, minor salivary glands", "opb": "Keratinised epithelium, absent submucosa, no salivary glands", "opc": "Non-keratinised epithelium, submucosa, minor salivary glands", "opd": "Non-keratinised epithelium, absent submucosa, minor salivary glands", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "f8bd7ba3-6393-42ff-886e-617391a8f9d2", "choice_type": "single"} {"question": "One is not the feature of obstructive jaundice", "exp": "Features of Obstructive jaundice Most common cause of obstructive jaundice is CBD stones Characterized by dark urine, clay coloured stools, icterus and Pruritus Presence of urobilinogen in urine rules out obstructive jaundice USG is the best test to differentiate medical from surgical jaundice There is raised ALP levels, cholesterol and reduced Urobilinogen Ref: Harrison's 19th edition Pgno : 1998", "cop": 4, "opa": "Pruritus", "opb": "Elevated level of serum bilirubin", "opc": "Raised alkaline phosphatase", "opd": "Raised urinary urobilinogen", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "a97e5699-40ca-47b6-a37a-4ced726bf517", "choice_type": "single"} {"question": "Sphincter urethrae is present in", "exp": "The urethral sphincters are two muscles used to control the exit of urine in the urinary bladder through the urethra.The internal sphincter is a continuation of the detrusor muscle and is made of smooth muscle, therefore it is under involuntary or autonomic control. ref - BDC 6e vol2 pg372-376", "cop": 4, "opa": "Prostatic urethrae", "opb": "Spongy urethrae", "opc": "Membranous urethrae", "opd": "Penile urethrae", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "45861c0d-5f7e-427a-baef-7e46c6f503e9", "choice_type": "single"} {"question": "The only non catecholamine sympathomimetic drug out of the following is", "exp": "Ref-Goodman and Gillman 11/e p239 Catecholamine are the drugs having dihydrobenzene nucleus in it's structure.adrenaline, isoprenaline and dopamine contain this structure", "cop": 2, "opa": "Adrenaline", "opb": "Ephedrine", "opc": "Dopamine", "opd": "Isoprenaline", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "e799d69f-6ae5-43fd-ae4d-61bdbffab5ae", "choice_type": "single"} {"question": "The intervillous space of the placenta contains", "exp": "The intervillous space contains only maternal blood as the spiral aeries of the endometrium penetrate the outer cytotrophoblast shell.", "cop": 1, "opa": "Maternal blood", "opb": "Fetal blood", "opc": "Maternal and fetal blood", "opd": "Amniotic fluid", "subject_name": "Anatomy", "topic_name": "General Embryology 1", "id": "49793b5b-c265-4826-ba6e-b9e91c3a812b", "choice_type": "single"} {"question": "Sho head of Biceps is attached to", "exp": "The sho head of biceps brachii arises from the tip of the coracoid process and gets attached to the posterior rough pa of the radial tuberosity. The tendon is twisted; the anterior fibres become lateral and posterior fibres become media. The tendon is separated from the anterior pa of tuberosity by a bursa. Mnemonic Biceps brachii muscle origins: You walk shoer to a street corner .you ride longer on a superhighway. The sho head originates from the coracoid process. The long head originates from the supraglenoid tubercle. Ref- BD Chaurasia 7th edition Page no: 91 Figure:8.3 page no 89,BD chaurasia, 6th edition", "cop": 1, "opa": "Coracoid process", "opb": "Acromion process", "opc": "Supraglenoid tubercle", "opd": "Bicipital groove", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "614f8cd1-1310-415a-9e1d-a5e219dd789e", "choice_type": "single"} {"question": "A dome shaped skull is known as", "exp": null, "cop": 2, "opa": "Brachy-cephaly", "opb": "Oxy-cephaly", "opc": "Scapho-cephaly", "opd": "Rhomb-encephaly", "subject_name": "Anatomy", "topic_name": null, "id": "15e93d47-a1dc-4b5b-ac2b-5404a7b165f9", "choice_type": "single"} {"question": "Function of anconeus is", "exp": "ANCONEUS:- Origin: back of lateral epicondyle.Inseion:-lateral side of olecranon process. and upper surface of posterior surface of ulna.Nerve supply: nerve to anconeus. (Branch of radial nerve)Action:weak extensor of elbow joint.{Reference: vishram singh, pg no.129}", "cop": 4, "opa": "Pronation", "opb": "Supination", "opc": "Flexion", "opd": "Extension", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "92e6b57e-4df2-4143-9137-31d566358c7a", "choice_type": "single"} {"question": "On Congo red staining amyloid is seen as", "exp": "Ref Robbins 9/e 257 Congo red under ordinary light impas a pink or red colour to amyloid deposits.under polarized light, the Congo red stained amyloid shows a green birefringence", "cop": 3, "opa": "Dark brown colour", "opb": "Blue colour", "opc": "Brilliant pink colour", "opd": "Khaki colour", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5d85855c-9f86-4873-a33a-6eb99794d5a6", "choice_type": "single"} {"question": "Most common cause of left sided hea failure is", "exp": "Refer robbins 9/e 529 Myocardial infarction (MI), also known as a hea attack, occurs when blood flowdecreases or stops to a pa of the hea, causing damage to the hea muscle. The most common symptom is chest pain or discomfo which may travel into the shoulder, arm, back, neck or jaw. Often it occurs in the center or left side of the chest and lasts for more than a few minutes.The discomfo may occasionally feel like heaburn. Other symptoms may include shoness of breath, nausea, feeling faint, a cold sweat or feeling tired. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause hea failure, an irregular heabeat, cardiogenic shock or cardiac arrest", "cop": 1, "opa": "Myocardial infarction", "opb": "Systemic hypeension", "opc": "Rheumatic hea disease", "opd": "Infective endocarditis", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "acddae55-5155-40a5-a941-7b253fe29033", "choice_type": "single"} {"question": "Inferior thyroid vein drains into", "exp": "The inferior thyroid veins emerge at the lower border of the isthmus. They form a plexus in front of the trachea and drain into the left brachiocephalic vein. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Internal jugular vein", "opb": "Superior vena cava", "opc": "Brachiocephalic vein", "opd": "EXternal jugular vein", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1fc03c0c-da56-4599-94d8-bbeaa97a35ab", "choice_type": "single"} {"question": "Distance of the Lower Esophageal Sphincter from the upper incisors is", "exp": "Lower oesophageal sphincter is seen in lower pa of oesophagus where it pierces diaphram. It is 37.5cm/15inch from incisor teeth. Ref - BDC vol 1 6th edition pg 282", "cop": 4, "opa": "15cm", "opb": "22.5cm", "opc": "27.5cm", "opd": "37.5cm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ebc3ec71-d033-4cdf-bdd6-fdc3d430ec73", "choice_type": "single"} {"question": "Depression of the fragments for the comminuted fracture seen in", "exp": "Depressed comminuted fracture In this type of fracture, there will be depression of the fragments of the comminuted fracture. It is usually caused by striking with an object having a small striking surface. It can also be caused by impact from a relatively large projecting object as in traffic accidents. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 163", "cop": 2, "opa": "Fissured fracture", "opb": "Depressed comminuted fracture", "opc": "Ring fracture", "opd": "Pond fracture", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "3a177ef7-276e-4abf-a74c-2f364b191322", "choice_type": "single"} {"question": "Palatine tonsil develops from", "exp": null, "cop": 2, "opa": "Dorsal part of II pharyngeal pouches", "opb": "Ventral part of II pharyngeal pouches", "opc": "Dorsal part of III pharyngeal pouches", "opd": "Ventral part of I pharyngeal pouches", "subject_name": "Anatomy", "topic_name": null, "id": "ca5cf9de-1c1d-4520-afec-0ec291c29156", "choice_type": "single"} {"question": "Most potent stimulator of native T cells", "exp": "Ref Robbins 9/e p191 Naive T cells leave the thymus and home to secondary lymphoid organs. Dendritic cells are the most potent activators of naive T cells. DCs carry antigen from the periphery to the draining lymph nodes. ... CD28 signaling provides \"Signal 2\" to T cells and is necessary for T cell activation.", "cop": 1, "opa": "Mature dendritic cells", "opb": "Follicular dendritic cells", "opc": "Macrophage", "opd": "B cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7ae341af-8438-4e2d-b8b4-e1d839bb2ebc", "choice_type": "single"} {"question": "Courvoiser's law is related to", "exp": "Courvoiser's law In obstruction of the common bile duct due to Stone, distension of gall bladder seldom occurs, the organ usually is shriveled If there is no disease in the gall bladder and the obstruction is due to cancer of ampulla, pancreas or bile duct, then gall bladder will be distended Ref: Sabiston 20th edition Pgno : 1544", "cop": 1, "opa": "Jaundice", "opb": "Ureteric calculi", "opc": "Poal hypeension", "opd": "The length of skin flap in skin grafting", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "670e791e-ea40-4b70-a753-0d935c651953", "choice_type": "single"} {"question": "Largest organelle in eukaryote is", "exp": "The Nucleus - The nucleus constitute the central, more dense, pa of the cell. It is usually rounded or ellipsoid. Occasionally it may be elongated, indented or lobed. It is the largest cell organelle measuring 4-10 um in diameter. All cells in the body contain nucleus, except mature red blood cells (RBCs) in circulation. Nuclear Components - Chromatin, Nucleolus, Nuclear membrane, Nucleoplasm. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no., 28.", "cop": 2, "opa": "ER", "opb": "Nucleus", "opc": "Cytoskeleton", "opd": "Golgi body", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "db9bd7e9-20e2-4272-9cfb-2a50e73db6f3", "choice_type": "single"} {"question": "Most common cause of liver abscess is", "exp": "E.coli most common in Western countries Klebsiella pneumonia most common in Asian countries Staphylococcus most common in children suffering from chronic granulomatous disease", "cop": 2, "opa": "Proteus", "opb": "E.coli", "opc": "Klebsiella", "opd": "Staphylococcus", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "97ba3480-ec06-446e-af6d-163bba879bf7", "choice_type": "single"} {"question": "Prophylactic maintenance level of lithium is", "exp": "Just facts", "cop": 1, "opa": "0.6-0.8 mEq/L", "opb": "0.8-1.2 mEq/L", "opc": "2-4 mmol /L", "opd": "2-4 mEQ/L", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7aae151f-f6eb-42ed-bf11-5bc861abda95", "choice_type": "single"} {"question": "Difference between typical cervical & thoracic veebra", "exp": "CERVICAL VEEBRAE They are identified by the presence of foramen transversaria.There are seven cervical veebrae,out of which the third to sixth are typical,while the first,second and seventh are atypical. Typical cervical veebra Body 1.The body is small and broader from side to side than from before backwards. 2.The superior surface is concave transversely with upward projecting lips on each side. 3.The inferior surface is saddle shaped,being convex from side to side and concave from before backwards. 4.The anterior and posterior surfaces resemble that of other veebrae. Veebral Foramen It is larger than the body.It is triangular in shape because the pedicles are directed backwards and laterally. Veebral Arch 1.The pedicles are directed backwards and laterally. 2.The laminae are relatively long and narrow,being thinner above than below. 3.The superior and inferior aicular processes form aicular pillars which project laterally at the junction of pedicle and the lamina. 4.The transverse processes are pierced by foramina transversaria. REF.BD CHAURASIA'S HUMAN ANATOMY,FIFTH EDITION,VOL 3.PAGE NO 40", "cop": 2, "opa": "Has a triangular body", "opb": "Has a foramen transversarium", "opc": "Superior aicular facet directed backwards & upwards", "opd": "Has a large veebral body", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "03de0816-dc57-46c8-affd-92e5a5170ab9", "choice_type": "single"} {"question": "Psychological antagonist is found in", "exp": "(Ref Katzung 12/e p20) Physiological antagonists are those drugs that produce opposite action by acting on different receptors. Adrenaline reverses the bronchoconstrictor action of histamine (. H1 receptors) by causing bronchodilation (through beta2 receptors). Therefore,these are physiological antagonists.", "cop": 4, "opa": "Isoprenaline and sulbutamol", "opb": "Isoprenaline and adrenaline", "opc": "Isoprenaline and propranolol", "opd": "Adrenaline and histamine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b7b3f507-a8d6-441e-b2fe-36b67044dbe6", "choice_type": "single"} {"question": "Centrilobular necrosis is seen in", "exp": "Refer Robbins page no 872 8th edition Centrilobular necrosis refers to the necrosis of the centrilobular tissue of the hepatic lobule. The centrilobular zone of the lobule is most prone to metabolic toxins such as those generated in alcoholic hepatitis.", "cop": 1, "opa": "CCL4", "opb": "White phosphorus", "opc": "Yellow fever", "opd": "Eclampsia", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "5c8426cb-a857-4641-a10a-d49410fb78b0", "choice_type": "single"} {"question": "Ciliary muscles develop It", "exp": "Ans. b. Neural crest cellGrays Anatomy 40/e p702, Ciliary muscles develop from Neural crest.", "cop": 2, "opa": "Surface ectoderm", "opb": "Neural crest cell", "opc": "Mesoderm", "opd": "Neuroectoderm", "subject_name": "Anatomy", "topic_name": null, "id": "d135c2f1-115b-41ea-b882-36a3a5960be8", "choice_type": "single"} {"question": "Cervical oesophagus corresponds to", "exp": "Cervical esophagus stas at inferior margin of cricoid cailage that corresponds to corpus of 6th cervical veebra. This level is marked by a carotid tubercula named \"Chasseing tubercula,\" which is an impoant landmark in cervical esophagectomy. Cervical esophagus ends at inferior edge of first dorsal veebra that comes up to a horizontal plane of jugular incisura of sternum. The endpoint is the staing point of upper mediastinum, and from this point it is thoracic esophagus. Cervical esophagus is 5-6 cm long, and its luminal diameter is 1.4-1.5 cm at its narrowest point. Ref -100gm UTI: Recurrent episodes of UTI (and not a single episode) are an absolute indication for surgery of prostate. Hypeension: Alpha blockers which are first line medical therapy for BPH lower the blood pressure and thus are helpful in hypeensive persons. Management of BPH Management is primarily directed by symptoms. Mild symptoms can be managed with watchful waiting. More severe symptomatic patients are treated with medicines (alpha blockers, 5-alpha reductase inhibitors or combination of both). Surgery is recommended if the patient is having problems despite medical therapy. Absolute indications for surgery as listed in Smith's Urology is given below. Absolute indications for surgical treatment of BPH Refractory urine retention (failing at least one attempt at catheter removal) Recurrent UTI from BPH Bladder stones d/t BPH Renal insufficiency d/t BPH Large bladder diveicula secondary to BPH Recurrent gross hematuria from BPH Upper tract dilatation is an indication for surgery according to Schwaz. Medical therapy Alpha-blockers (terazosin, doxazosin, and tamsulosin) Alpha-blockers help is reducing the symptoms of BPH by blocking the alpha 1 adrenoreceptors present in human prostate and bladder base. 5-Alpha-reductase inhibitors (Finasteride, Dutasteride) - 5-alpha-reductase inhibitors block the conversion of testosterone to dihydrotestosterone. This thus results in reduction in the size of the gland and improvement in symptoms (after several months of use). Surgery Surgery for BPH is most commonly performed endoscopically; however, if the prostate gland is quite large (approx >100 g), an open prostatectomy should be performed. The standard endoscopic procedure for BPH is a transurethral resection (TUR) of the prostate. Conventional surgical methods: Transurethral resection of the prostate (most commonly used method) Transurethral incision of the prostate (TUIP) Open simple prostatectomy (simple suprapubic prostatectomy, simple retropubic prostatectomy) - When the prostate is too large to be removed endoscopically, an open enucleation is necessary. What constitutes \"too large\" is subjective and varies depending upon the surgeon's experience with TURP. Glands >100 g are usually considered for open enucleation. Open prostatectomy may also be initiated when concomitant bladder diveiculum or a bladder stone is present or if dorsal lithotomy positioning is not possible. Open prostatectomies can be done with either a suprapubic or retropubic approach. A simple suprapubic prostatectomy is performed transvesically and is the operation of choice in dealing with concomitant bladder pathology. Minimally invasive methods: Laser therapy (Nd:YAG and holmium:YAG ) Transurethral electro vaporization of the prostate Microwave Hypehermia Transurethral needle ablation of the prostate- High-intensity focused ultrasound for thermal tissue ablation Intraurethral stents--stents are endoscopically placed in the prostatic fossa and are designed to keep the prostatic urethra patent. They are usually covered by urothelium within 4-6 months after inseion. These devices are typically used for patients with limited life expectancy who are not deemed to be appropriate candidates for surgery or anesthesia. Ref : Schwaz 8/e p1528-31", "cop": 4, "opa": "Prostate size >75gm", "opb": "Single episode of UTI requiring 3 day antibiotics", "opc": "Cannot use medication due to hypeension", "opd": "Bilateral hydronephrosis", "subject_name": "Anatomy", "topic_name": "Urology", "id": "0794f766-891f-4238-90de-888368ede29d", "choice_type": "single"} {"question": "Dysttropic calcification is seen in", "exp": "Ref, Robbins 8/e p38,9/e p9/e65", "cop": 1, "opa": "Atheroma", "opb": "Paget's disease", "opc": "Renal osteodystrophy", "opd": "Milk alkali syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6d084cfc-569a-466a-bfd2-c7e632c26d12", "choice_type": "single"} {"question": "Arrange coverings on peripheral nerve from inner to outer", "exp": "coverings on peripheral nerve from inner to outer are Endoneurium, Perineurium, EpineuriumINDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY PAGE NO:171", "cop": 2, "opa": "Endoneurium, Epineurium, Perineurium", "opb": "Endoneurium, Perineurium, Epineurium", "opc": "Perineurium, Endoneurium, Epineurium", "opd": "Epineurimn, Endoneuriu, Perineurium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1fe8c133-2971-495a-90fd-63e171f2dc2f", "choice_type": "single"} {"question": "Middle 1.5 cm of anal canal is lined by", "exp": "The anal canal is divided into three pas. The zona columnaris is the upper half of the canal and is lined by simple columnar epithelium. The lower half of the anal canal, below the pectinate line, is divided into two zones separated by Hilton's white line. The two pas are the zona hemorrhagic and zona cutanea, lined by atratified squamous non keratinized and stratified squamous keratinized. ref - BDC vol2 pg416", "cop": 2, "opa": "Keratinized stratified squamous epithelium", "opb": "Non keratinized stratified squamous epithelium", "opc": "Columnar epithelium", "opd": "Psudocolumnar epithelium", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "327bc019-7109-4162-b765-f961785143da", "choice_type": "single"} {"question": "\"Turkish Saddle\" refers to", "exp": "Turkish Saddle refers to sella turcica, which is the seat for pituitary gland. The pituitary gland sits in a little cup-shaped bone (the sphenoid) which actually looks quite like a saddle: The name the classical anatomists gave it is the sella turcica, presumably because the classical Turkish saddle was designed to cup the rider's bottom. ref - researchgate.net", "cop": 2, "opa": "Hypothalamus", "opb": "Pituitary gland", "opc": "Amygdaloid body", "opd": "Uncus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "576c130a-ada6-4387-b074-bff08cf2cfc6", "choice_type": "single"} {"question": "Cista terminalis is present in", "exp": "Cista Terminalis is present in the right atrium. It is a muscular ridge that runs anteriorly along the atrial wall from the opening of the superior vena cava. It corresponds externally to Sulcus terminalis. It is the site of origin of pectinate muscles. It divides the right atrium into a smooth posterior pa and a rough anterior pa. Both the vena cavae empty into the posterior smooth pa. Ref: Gray&;s Anatomy 41st edition. Pgno: 1000", "cop": 1, "opa": "Right Atrium", "opb": "Left Atrium", "opc": "Right Ventricle", "opd": "Left Ventricle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ffad4b61-ec7a-45fe-ac18-fedb84a1e4ae", "choice_type": "single"} {"question": "Spinal epidural space is the largest at the level of the", "exp": "Spinal epidural space is largest at 3rd lumbar veebrae .Spinal epidural space is a closed anatomic space between the dura mater and the bony spinal canal. It extends from the foramen magnum to the sacrum. Unlike its intracranial counterpa, spinal epidural space is real. The presence of anchoring plicae and meningoveebral ligaments divide the space into anterior, lateral and posterior compaments. Ref - pubmed.com", "cop": 4, "opa": "12th thoracic veebra", "opb": "1st lumbar veebra", "opc": "2nd lumbar veebra", "opd": "3rd lumbar veebra", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "158a3ed4-8496-4ab2-aad6-2f115d37680c", "choice_type": "single"} {"question": "tranylcypromine is a type of", "exp": "MAOI * IMPOANCE First class of antidepressant drugs that were introduced * MECHANISM There are three monoamines namely dopamine, adrenaline and serotonin. These mon amines are degraded by monoamine oxidase. MAOI inhibit this enzyme and acts increasing monoamines * DRUGS Phenelezine Tranylcipromine * USE ATYPICAL DEPRESSION, depression with reverse vegetative symptoms * SIDE EFFECTS Hypeensive crisis Cheese reaction When a patient on MAOI takes tyramine rich food like tyramine there will be increased release of monoamines. These excess monoamines cannot be degraded by MAO as it is blocked by MAOI. Thus, this may result in hypeensive crisis. Paresthesia's due to pyridoxine deficiency LIKE IPRONIAZID WEIGHT gain SEXUAL dysfunction ref. kaplon and sadock, synopsis of psychiatry, 11 th edition , pg no. 925", "cop": 3, "opa": "SNRI", "opb": "SSRI", "opc": "MAOI", "opd": "NDRI", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "519f4dae-6489-41d4-a5f3-04ee91cc5c2b", "choice_type": "single"} {"question": "Root value of axillary nerve is", "exp": "AXILLARY NERVE:-Root value: C5, C6Arises from the posterior cord of brachial plexus, near lower border of the subscapularis.Runs backward on Subscapularis to pass through quadrangular space along with posterior circumflex humeral aery.Here it is related to surgical neck of humerus.Nerve gives branch to shoulder joint and divide into anterior and posterior division.Anterior division:- teres minor and posterior pa of deltoid.Continues as upper lateral cutaneous nerve of arm and supplies skin over deltoid.Posterior division:-continues horizontally between deltoid and surgical neck of humerus along with posterior circumflex humeral vessels.supplies deltoid and few branches to innervate skin.Risk of damage in inferior dislocation of the head of humerus and fracture surgical neck humerus.Clinical presentation:-Impaired abduction of shoulder.Loss of sensation over lower half of deltoid- regimental badge area.Loss of shoulder contour with prominence of greater tubercle.{Reference:Vishram Singh, pg no. 78}", "cop": 1, "opa": "C5 C6", "opb": "C7 C8", "opc": "C8 T1", "opd": "C5 C6 C7 C8 T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "ff39e4cd-1b9d-4e17-9fb7-307c8a9fbe85", "choice_type": "single"} {"question": "Boundaries of ischiorectal fossa are", "exp": "The boundaries of ischiorectal fossa: floor: deep transverse perineal fascia. medial wall: external anal sphincters/anal canal; levator ani muscle. lateral wall: ischial tuberosity; obturator internus muscle; obturator fascia. apex: intersection of levator ani and obturator internus muscle ref - BDC vol2 pg415, researchgate.net", "cop": 3, "opa": "Posterior : Perineal membrane", "opb": "Anterior : Sacrotuberous ligament", "opc": "Lateral : Obturator internus", "opd": "Medial : Gluteus maximus", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "09eb02db-3ab4-4521-93cd-df882185bc65", "choice_type": "single"} {"question": "Gland derived from foramen caecum is", "exp": "A. i.e. Thyroid", "cop": 1, "opa": "Thyroid", "opb": "Parathyroid", "opc": "Parathyroid", "opd": "Parathyroid", "subject_name": "Anatomy", "topic_name": null, "id": "101db3a7-cb26-4529-b74f-77a36390d481", "choice_type": "single"} {"question": "Peroneus longus is supplied by", "exp": "SUPERFICIAL PERONEAL:-Muscular branches: peroneus longus and brevis Cutaneous branches:Digital branches to medial side of big toe,adjacent sides of 2nd and 3rd, 3rd and 4th ,and 4th and 5th toes. TIBIAL NERVE:-Root value:ventral division of ventral rami of L4,L5,S1,S2,S3 segments of spinal cord.Beginning: largest subdivision of sciatic nerve.Course: descends veically in popliteal fossa. It continues in back of leg as the neurovascular bundle with posterior tibial vessels. Lastly passes deep to flexor retinaculum of ankle joint.Branches:Muscular branches to gastrocnemius,soleus, popliteus, plantaris, FHL, FDL and Tibialis posterior.Aicular branches to superior,middle and inferior genicular .Cutaneous and vascular branch: sural nerve ,medial calcaneal branch and branch to posterior tibial aery.Terminates by dividing into medial and lateral plantar nerves.MEDIAL PLANTAR NERVE:-Muscular branches: Abductor hallucis, flexor digitorum brevis, flexor hallucis brevis and first lumbrical.Cutaneous branch: skin of medial pa of sole and medial three and a half toes.LATERAL PLANTAR NERVE:-Main trunk: flexor digitorum accessorius and abductor digiti minimi ans skin of sole. Ends by dividing into superficial and deep branches.Superficial branch: lateral and medial branch Lateral branch:flexor digiti minimi brevis, 3rd plantar, 4th interossei and skin on lateral side of little toe.Medial branch :4th interdigital cleft. Deep branch:2nd,3rd,4th lumbricals1st,2nd,3rd dorsal interossei 1st,2nd plantar interossei andAdductor hallucis. {Reference: BDC 6E }", "cop": 4, "opa": "Tibial nerve", "opb": "Sural nerve", "opc": "Deep peroneal nerve", "opd": "Superficial peroneal nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7a5662e8-64e9-4989-a7ea-b373be09922d", "choice_type": "single"} {"question": "The following muscle is an opener of the glottis", "exp": "1. Muscles which abduct the vocal cords: only posterior cricoarytenoids( safety muscles of larynx) 2. Muscles which adduct the vocal cords: * lateral cricoarytenoids * transverse aenoid * cricothyroid *thyroarytenoids 3. Muscles which tense the vocal cords: cricothyroid 4.muscles which relax the vocal cords: * thyroarytenoids * vocalis 4. Muscles which close the inlet of the larynx * oblique arytenoids * aryepiglottic 5.muscles which open the inlet of larynx : Thyroepiglotticus Ref BDC volume 3; 6th edition pg 258", "cop": 2, "opa": "Lateral cricoarytenoid", "opb": "Posterior cricoarytenoid", "opc": "Transverse arytenoid", "opd": "Inter arytenoids", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "13bf3aff-1e4b-44c5-84a3-042f8e4732a1", "choice_type": "single"} {"question": "Pancreatitis may be produced by following drugs", "exp": "Drugs associated with pancreatitis Definitive cause (MAD CAT PET TV FM) 6-Mercaptopurine Azathioprine Dideoxyinosine Cytosine arabinoside 5-Aminosalicylate Tetracycline Pentamidine Estrogens Trimethoprim - Sulfamethoxazole Thiazide Valproic acid Furosemide Metronidazole Probable cause (PILAAS) Phenformin Procainamide Isoniazid L-Asperaginase Acetaminophen Alpha-Methyl-dopa Sulindac Ref: Sabiston 20th edition Pgno : 1526", "cop": 2, "opa": "Colchicine", "opb": "L-Asperaginase", "opc": "Ciprofloxacin", "opd": "Nalidixic acid", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "56acdfb3-adc3-4158-b0f9-e10968c7898a", "choice_type": "single"} {"question": "Dropped shoulder occurs due to paralysis of", "exp": "Elevation of the scapula (as in shrugging the shoulders)The movement is brought about by the upper fibres of the trapezius and by the levator scapulae. It is associated with the elevation of the lateral end, and depression of the medial end of the clavicle. Spinal accessory nerve supplies trapezius muscle and may get injured in trauma or damage during surgery, resulting in weakness of the trapezius muscle and drooping of shoulder.", "cop": 2, "opa": "Deltoid", "opb": "Trapezius", "opc": "Teres minor", "opd": "Serratus anterior", "subject_name": "Anatomy", "topic_name": "Upper limb bones and muscles (proximal region) & Scapular movements", "id": "cbd1438f-9d3e-4693-8ba2-920120a9d30e", "choice_type": "single"} {"question": "The right gastroepiploic aery is a branch of", "exp": "Right gastroepiploic aery, a branch of gastroduodenal supplies the greater curvature of the stomach. Ref: BD Chaurasia; Volume 3; 6th edition; Page no: 252", "cop": 2, "opa": "Right Hepatic aery", "opb": "Gastroduodenal aery", "opc": "Hepatic aery", "opd": "Superior mesenteric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "05602c6a-ef37-4b21-9180-0c1ba8d45ca0", "choice_type": "single"} {"question": "Tip of spine of Sphenoid is related to", "exp": "The spine of the sphenoid is related laterally to the auriculotemporal nerve, and medially to the chorda tympani nerve and auditory tube. Its tip provides attachment to the sphenomandibular ligament. Its anterior aspect gives origin to the most posterior fibers of the tensor veli palatini muscleReference: Chourasia; 6th edition; 18th page", "cop": 4, "opa": "Auriculotemporal nerve", "opb": "Posterior fibres of Tensor veli palatini", "opc": "Auditory tube", "opd": "Sphenomandibular ligament", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1ecac637-e620-4566-a1e4-a87d440958fc", "choice_type": "single"} {"question": "Ulnar paradox is seen in", "exp": "Ulnar claw hand is seen in lower ulnar nerve palsy not Iin high ulnar nerve palsy It is called as ulnar paradox Ulnar paradox # Not severe claw hand deformity, but inability to flex DIP and weakness of flexing MCP & PIP of digits IV and V # Seen with higher nerve injuries (cubital tunnel syndrome) # More severe muscle impairment # FDP and lumbricals for digits IV and V are impaired, there is unopposed action of the Extensor digitorum Claw hand of the first and second finger Refer maheswari 9th ed", "cop": 1, "opa": "High ulnar lesion", "opb": "Low ulnar lesion", "opc": "Triple nerve injuries", "opd": "Combined ulnar and median nerve injuries", "subject_name": "Anatomy", "topic_name": null, "id": "7fbed6d2-5cef-4534-b132-5c177404ad3b", "choice_type": "single"} {"question": "agranuloctosis is a side effect of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 4, "opa": "risperidone", "opb": "clonazepam", "opc": "olanzapine", "opd": "carbamezepine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "0ce59744-583b-4f30-a84e-beaf94c7826d", "choice_type": "single"} {"question": "Most common position of appendix is", "exp": "The tip of the appendix can have a variable position within the abdominal cavity : retro-caecal (65-70%) pelvic (25-30%) pre- or post-ileal (5%) Ref - BDC 6e vol2 pg269", "cop": 4, "opa": "Pre ilial", "opb": "Post ilial", "opc": "Pelvic", "opd": "Retro caecal", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "2f10aca9-8d4d-4f07-8bb3-f14d534aba20", "choice_type": "single"} {"question": "Benign Prostatic hyperophy results in obstruction of the urinary tract. The specific condition is associated with enlargement of the", "exp": "Anatomically the median and lateral lobes are usually enlarged, due to their highly glandular composition. BPH typically affects the submucous group of glands in the transitional zone The anterior lobe has little in the way of glandular tissue and is seldom enlarged. Carcinoma of the prostate typically occurs in the posterior lobe. Ref BDC vol2 6e pg403", "cop": 3, "opa": "Anterior lobes", "opb": "Posterior lobes", "opc": "Median lobe", "opd": "Peripheral zone", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ffc6082a-4e97-4861-b451-a0f2c2a3250c", "choice_type": "single"} {"question": "The drug most likely to be responsible for accurate pancreatic disease", "exp": "Ref-KDT 6/e p771 Didanosine is most commonly implicated anti-retroviral drug in causing acute pancreatitis. Maximum chances ot peripheral neuropathy are seen with stavudine", "cop": 1, "opa": "Didanosine", "opb": "Ketokonazole", "opc": "Saquninavir", "opd": "Zidovudine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "4956f4fa-a788-4ba3-8e77-ac9bc7b9fe0f", "choice_type": "single"} {"question": "In Peritonsillar Abscess, pain is referred to ear due to", "exp": "In Peritonsillar Abscess or Quinsy, pain is referred to ear Glossopharyngeal Nerve (Tympanic or Jacobson's branch of Tympanic Plexus) because it is passing close to the peritonsillar space which might get irritated due to inflammation. Thus leading to referred otalgia in the patient", "cop": 2, "opa": "Facial Nerve", "opb": "Glossopharyngeal Nerve", "opc": "Vagus Nerve", "opd": "AuriculoTemporal Nerve", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "738668e4-8ddc-4343-89c4-679f5acbfa46", "choice_type": "single"} {"question": "Chediak_higashi syndrome is due to defect in", "exp": "Ref Walter and Israel 7/e p150 Chediak Higashi syndrome is an autosomal ressive Condition in which polymorphs exhibit defective random movements , defective chemotaxis and impairee degranulation on phagocytosis paicles", "cop": 2, "opa": "Opsonisation", "opb": "Chemotaxis", "opc": "LAD", "opd": "Extracellular microbacterial killing", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "75a617dc-002e-4043-808b-7acdfd05597f", "choice_type": "single"} {"question": "Hamaoma is", "exp": "Ref Robbins 8/e p262;7/e p272; 9/e p267 Hamaomatous Polyps Hamaomatous polyps occur sporadically and as compo- nents of various genetically determined or acquired syn- dromes (Table 14-6). As described previously, hamaomas are disorganized, tumor-like growths composed of mature cell types normally present at the site at which the polyp develops. Hamaomatous polyposis syndromes are rare, but they are impoant to recognize because of associated intestinal and extraintestinal manifestations and the need to screen family members. Juvenile Polyps Juvenile polyps are the most common type of hamaoma- tous polyp. They may be sporadic or syndromic. In adults, the sporadic form sometimes is also referred to as an inflam- matory polyp, paicularly when dense inflammatory infil- trates are present. The vast majority of juvenile polyps occur in children younger than 5 years of age. Juvenile polyps characteristically are located in the rectum, and most manifest with rectal bleeding. In some cases, prolapse occurs and the polyp protrudes through the anal sphincter. Sporadic juvenile polyps are usually solitary but in persons with the autosomal dominant syndrome of juvenile pol- yposis the number varies from 3 to as many as 100. Colec- tomy may be required to limit the hemorrhage associated with polyp ulceration in juvenile polyposis. Dysplasia occurs in a small propoion of (mostly syndrome- associated) juvenile polyps, and the juvenile polyposis syn- drome is associated with increased risk for the development of colonic adenocarcinoma. hamaomatous polyps and mucocutaneous hyperpigA mentation that carries an increased risk of several malig- nancies, including cancers of the colon, pancreas, breast, lung, ovaries, uterus, and testes, as well as other unusual neoplasms. Germ line heterozygous loss-of-function muta- tions in the gene LKB1/STK11 are present in approximately half of the patients with the familial form of Peutz-Jeghers syndrome, as well as a subset of patients with the sporadic form. Intestinal polyps are most common in the small intestine, although they may also occur in the stomach and colon and, rarely, in the bladder and lungs. On gross evaluation, the polyps are large and pedunculated with a lobulated contour. Histologic examination demonstrates a characteristic arborizing network of connective tissue, smooth muscle, lamina propria, and glands lined by normal-appearing intestinal epithelium (Fig. 14-31, B", "cop": 2, "opa": "Proliferation of cells in foreign site", "opb": "Proliferation of native cells in tissue", "opc": "Malignant condition", "opd": "Acquired condition", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "81c054b4-9eea-487b-938b-63090a7d8bdb", "choice_type": "single"} {"question": "Right fouh arch aery gives rise to", "exp": ".", "cop": 1, "opa": "Right subclan aery", "opb": "Common carotid aery", "opc": "Internal carotid aery", "opd": "External carotid aery", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "104a5921-6307-46aa-887d-abf9c479a7b1", "choice_type": "single"} {"question": "Inferior thyroid aery is related to", "exp": "The inferior thyroid aery is a branch of thyrocervical trunk. It runs first upwards then medially and finally downwards to reach the lower pole of the gland. During its course, it passes behind the carotid sheath and the middle cervical sympathetic ganglion; and in front of the thyroid veebral vessels; and gives off branches to adjacent structures Its terminal pas is intimately related to the recurrent laryngeal nerve, while proximal pa is away from the nerve. The aery divides into 4 to 5 glandular branches which pierce the fascia separately to reach the lower pa of the gland. One ascending branch anastomoses with the posterior branch of the superior thyroid aery, and supplies the parathyroid glands. Ref BDC volume 3 :sixth edition :pg 143", "cop": 2, "opa": "Superior laryngeal nerve", "opb": "Recurrent laryngeal", "opc": "Glossopharyngeal nerve", "opd": "XII nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "058f3972-2801-43a6-a089-b8dea353109a", "choice_type": "single"} {"question": "Ventral merogastrium gives rise to", "exp": null, "cop": 2, "opa": "Liver omentum", "opb": "Greater omentum", "opc": "Gastrophrenic ligament", "opd": "Gastrophrenic ligament", "subject_name": "Anatomy", "topic_name": null, "id": "56b5c399-7f37-4aea-9de4-acf8d98350ef", "choice_type": "single"} {"question": "First branch of subclavian artery is", "exp": null, "cop": 3, "opa": "Internal thoracic artery.", "opb": "Thyrocervical trunk.", "opc": "Vertebral artery.", "opd": "Costocervical trunk.", "subject_name": "Anatomy", "topic_name": null, "id": "f6810cf9-6618-47f6-83a4-d0fc6936cf72", "choice_type": "single"} {"question": "Spinal cord in an infant terminates at", "exp": "In premature & term neonates- it lies b/w 1st & 3rd lumbar veebrae. In children between ages of (1-7yrs)- it lies between 12th thoracic and 3rd lumbar veebra. In adults, it terminates at the level of middle 3rd of body of 1st lumbar veebra which corresponds approximately to transpyloric plane. Spinal cord occupies superior 2/3rd of veebral canal It continues cranially with medulla oblongata, just below the level of foramen magnum, at the upper border of atlas and terminates caudally as conus medullaris. During development, veebral column elongates more rapidly than spinal cord, so there is increasing discrepancy b/w anatomical level of spinal cord segments & their corresponding veebrae.", "cop": 3, "opa": "L1", "opb": "L2", "opc": "L3", "opd": "L4", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 3", "id": "37550fd7-46d1-4623-bb64-a1d925af5830", "choice_type": "single"} {"question": "Trigone of urinary bladder develops from", "exp": "The terminal poion of Mesonephric duct gets absorbed into the posterior wall of urogenital sinus and forms the trigone of the urinary bladder. Urinary bladder develops from endodermal vesicourethral canal. Ref: Gray's 39e/p-1289", "cop": 3, "opa": "Urogenital sinus", "opb": "Vesicourethral canal", "opc": "Mesonephric duct", "opd": "Endoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dc88705f-0d82-4db1-82f9-cbb2d708cc08", "choice_type": "single"} {"question": "Most common site of admantinomaof the long bones is", "exp": "Ameloblastoma---most common site jaw Ameloblastoma---most of long bones---called adamantinoma and is most common in tibial diaphysis Refer Ohopedic pathology 6th/e 449", "cop": 3, "opa": "Femur", "opb": "Ulna", "opc": "Tibia", "opd": "Fibula", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "5214780c-e734-4aca-a953-efdff2b104c3", "choice_type": "single"} {"question": "Deep branch of ulnar nerve innervates", "exp": "There are twenty muscles in hands of which all are supplied by the ulnar nerve Except the following five muscles which are supplied by median nerve: 1 Abductor pollicis brevis 2. Flexor pollicis brevis (also often receives additional supply from the deep branch of ulnar nerve) 3. Opponens pollicis 4. First lumbrical 5. Second lumbrical Note: Palmaris Brevis is supplied by the superficial branch of the ulnar nerve. All interossei are supplied by the deep branch of ulnar nerve.", "cop": 3, "opa": "I and II lumbricals", "opb": "Palmaris brevis", "opc": "Dorsal interossei", "opd": "Opponens pollicis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "0c4068a4-9474-417e-9c1f-a47cdf7efbc9", "choice_type": "single"} {"question": "Centromere near the end of chromosome", "exp": "Acrocentric REF: Precid & Strachan Molecular genetics, page 49, 153, http://en.wikipedia.org/wiki/ CentromereCentromere positionsEach chromosome has two arms, labeled p (the shoer of the two) and q (the longer). The p arm is named for \"petit\" meaning `small'; the q arm is named q simply because it follows p in the alphabet. (\"q\" refers to the French word \"queue\" meaning 'tail')Metacentric: A chromosome is metacentric if its two arms are roughly equal in length. In some cases, a metacentric chromosome is formed by balanced Robesonian translocation: the fusion of two acrocentric chromosomes to form one metacentric chromosome. Example 1, 3, 16, 19, 20.Submetacentric: If arms' lengths are unequal, the chromosome is said to be Submetacentric. Example-X chromosome, 2, 4, 12 , 17, 18Acrocentric: If the p (sho) arm is so sho that is hard to observe, but still present, then the chromosome is acrocentric (The \"acro-\" in acrocentric refers to the Greek word for \"peak\"). The human genome includes acrocentric Y-chromosomes, 13, 14, 15, 21 and 22Telocentric: A telocentric chromosome's centromere is", "cop": 1, "opa": "Acrocentric", "opb": "Metacentric", "opc": "Submetacentric", "opd": "Telocentric", "subject_name": "Anatomy", "topic_name": null, "id": "c3ea38df-cfc7-4263-853f-368070ec02d8", "choice_type": "single"} {"question": "Vitelline vein forms", "exp": "Inderbir Singh'sHuman embryology Tenth edition Pg 265 The pas of right and left vitelline that lie outside the substance of the liver undergo alterations leading to formation of poal vein 2 vitelline veins shows anastomosis before opening into sinus venosus that is 1dorsal and 2 ventral (proximal and distal). At dorsal anastomosis spleenic and superior mesentric vein joins vitelline vein poal vein is formed by:Dorsal anastomosis ventral anastomosis Right vitelline vein", "cop": 3, "opa": "Ligamentum venosum", "opb": "Ligamentum teres", "opc": "Poal vein", "opd": "Coronary sinus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3e2ce61c-821a-4ee2-8da0-4fa5686873b4", "choice_type": "single"} {"question": "In a case of chest pain with pericarditis and pericardial effussion, pain is referred by", "exp": "The fibrous and parietal pericardia are supplied by phrenic nerves.They are sensitive to pain.Pain of pericarditis originates in the parietal pericardium alone. B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION Page no-251", "cop": 1, "opa": "Phrenic nerve", "opb": "Superficial cardiac plexus", "opc": "Deep cardiac plexus", "opd": "Vagus nerve", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "0824b434-5704-4318-888f-028dd64dddfb", "choice_type": "single"} {"question": "Cytosolic chromosomes C plays an impoant function in", "exp": "* Cytosolic chromosomes C and apaf-1 are involved in intrinsic pathway of Apoptosis * mitochondrial cyt c and not cystolic cyt c is involved in aerobic respiration", "cop": 1, "opa": "A. Apoptosis", "opb": "B. Cell necrosis", "opc": "C. Electron transpo chain", "opd": "D. Cell division", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "20a7e473-3af7-4280-94d8-b536cd2d0480", "choice_type": "single"} {"question": "Nerve supply of muscle of palate is/are", "exp": "NERVE SUPPLY OF PALATE: Motor nerves-All muscles of soft palate except the tensor veli palatini are supplied by the pharyngeal plexus. The fibres of this plexus are derived from the cranial pa of accessory nerve through the vagus. The tensor veli palatini is supplied by mandibular nerve General sensory nerves are derived from- a.Middle and posterior lesser palatine nerves, which are branches of the maxillary nerve through the pterygopalatine ganglion b.The glossopharyngeal nerve Special sensory nerves or gustatory nerves carrying taste sensations from the oral surface are contained in the lesser palatine nerves. The fibres travel through the greater petrosal nerve to the geniculate ganglion of the facial nerve and from there to the nucleus of tractus solitarius Secretomotor nerves are also contained in the palatine nerves. They are derived from the superior salivatory nucleus and then travel through the greater petrosal nerve Ref.BDC volume 3,sixth edition pg 223", "cop": 1, "opa": "Glossopharyngeal nerve", "opb": "Vagus nerve", "opc": "Trigeminal nerve", "opd": "Greater palatine nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "4820e90d-1b12-43d0-8b44-356be7a6960c", "choice_type": "single"} {"question": "In Bing test, on alternately compressing and releasing the external acoustic meatus, the sound increases, and decreases. This indicates", "exp": "Tests for bone conduction TestPrincipleMethodImpressionBing test Examines the effect of occlusion of ear canal on hearing Tuning fork placed on mastoid while examiner alternatively closes & opens the ear canal by pressing on the tragus inwards Patient hears louder when ear canal is occluded & softer when ear canal is open - Normal persons or sensorineural deafness ( Bing + ve )No change on ear canal opening or occlusion - conductive deafness ( Bing - ve )Gelle's test Examines the effect ofincreased air pressure in ear canal on hearing Placing a vibrating fork on mastoid while changes in air pressure in ear canalare brought about by siegel's speculum Positive - normal persons or sensorineural deafnessNegative - ossicular chain fixed or disconnected(Refer: PL Dhingra, Textbook of Ear, Nose, Throat, 6thedition,pg no: 21,22,23)", "cop": 2, "opa": "Otosclerosis", "opb": "Sensorineural deafness", "opc": "Adhesive otitis media", "opd": "Chronic suppurative otitis media", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cdd7f8a4-9cc5-4826-9ce9-430f8ee66ef2", "choice_type": "single"} {"question": "A patient with a prosthetic hea valve develops endocarditis eight months after Valve replacement. Most likely organisms responsible is", "exp": "Ref Harrison 19 th ed pg 816 Prosthetic valve endocarditis (PVE) arising within 2 months of valve surgery is generally nosocomial, the result of intraoperative contami- nation of the prosthesis or a bacteremic postoperative complication. This nosocomial origin is reflected in the primary microbial causes: S. aureus, CoNS, facultative gram-negative bacilli, diphtheroids, and fungi. The poals of entry and organisms causing cases beginning >12 months after surgery are similar to those in community-acquired NVE. PVE due to CoNS that presents 2-12 months after surgery often represents delayed-onset nosocomial infection. Regardless of the time of onset after surgery, at least 68-85% of CoNS strains that cause PVE are resistant to methicillin.", "cop": 1, "opa": "Staphylococcus aureus", "opb": "Streptococcus Viridians", "opc": "Salmonella faecalis", "opd": "HACEK Group", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "eeaf7e5b-14b6-4acd-ba88-5ecfdbb3acdc", "choice_type": "single"} {"question": "Right gastric aery is a branch of(2018)", "exp": "The right gastric aery arise from the hepatic aery. Ref:-grays anatomy, pg num:-1116", "cop": 2, "opa": "A) Coeliac trunk", "opb": "B) Hepatic aery", "opc": "C) Gastroduodenal aery", "opd": "D) splenic aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "5936a7a6-bfbc-478c-9943-db0d76bdbd23", "choice_type": "single"} {"question": "Ascent of horse shoe shaped kidney is prevented by", "exp": "Initialy in IUL(intrauterine life) kidneys are present in iliac fossa , Kidney has to reach the level of renal aery which is prevented by inferior mesenteric aery which is a branch of abdominal aoa. Fusion of right and left kidney occurs to form a U shaped structure at the level below inferior mesenteric aery.", "cop": 2, "opa": "Superior mesenteric aery", "opb": "Inferior mesenteric aery", "opc": "Superior mesenteric vein", "opd": "Inferior mesenteric vein", "subject_name": "Anatomy", "topic_name": "GIT 1", "id": "97000d9e-e725-4572-8597-9cbbc54fa298", "choice_type": "single"} {"question": "The epithelial lining of the urethra below the opening of the ejaculatory ducts is", "exp": "The epithelium of the urethra stas off as transitional cells as it exits the bladder. Fuher along the urethra there are psuedostratified columnar and stified columnar epithelia, then stratified squamous cells near the external urethral orifice. There are small mucus-secreting urethral glands, that help protect the epithelium from the corrosive urine. Ref - wikipedia.org", "cop": 2, "opa": "Stratified cuboidal epithelium", "opb": "Stratified columnar epithelium", "opc": "Transitional epithelium", "opd": "Stratified squamous epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a8fae452-37bb-4d32-b9f6-4469e8951f6d", "choice_type": "single"} {"question": "A tangential cut by sword or butcher's knife produces", "exp": "Gutter fracture In this, the outer pa of the bone us chipped off by a tangential force and a gutter is formed. Gutter fracture is caused by a bullet touching the outer table and is not penetrating the skull This can also be produced by a tangential cut by a sword or butcher's knife. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 163", "cop": 3, "opa": "Greenstick fracture", "opb": "Ring fracture", "opc": "Gutter fracture", "opd": "Sutural fracture", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "c7d481e5-0b41-4860-91c7-56f5cbf9495f", "choice_type": "single"} {"question": "Commonest cancer in a renal transplant recipient is", "exp": "Cancers seen in renal transplant recipients in decreasing order are: Skin cancer > Lymphoma > Kaposi's Sarcoma > Ca Cervix > Renal tumors > Ca Vulva & perineum. Ref : Cambell's Urology 8/e p372", "cop": 4, "opa": "Kaposi sarcoma", "opb": "Renal cell carcinoma", "opc": "Ca cervix", "opd": "Skin cancer", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "83a835b6-97d3-49c9-8edf-e1a42ede67d6", "choice_type": "single"} {"question": "Fetal hydrops is most commonly associated with", "exp": "Cardiac anomaly is the most common anatomical abnormality associated with fetal hydrops. In general, hydrops associated with a structurally abnormal hea carries a poor prognosis, as the anomaly is usually severe.", "cop": 1, "opa": "Cardiac anomalies", "opb": "Renal anomalies", "opc": "GI anomalies", "opd": "Skeletal anomalies", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b5b945dd-f5b9-4bd9-b570-5215deb8d612", "choice_type": "single"} {"question": "Internal carotid aery crosses", "exp": "Inside the middle cranial fossa, it first runs forwards along the floor and medial wall of the cavernous sinus and then turns upwards on the medial side of the anterior clinoid process.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 175)", "cop": 3, "opa": "Sigmoid sinus", "opb": "Straight sinus", "opc": "Cavernous sinus", "opd": "Saggital sinus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "d8a72711-c6fb-4a9e-9bc0-4bb7f0c37a92", "choice_type": "single"} {"question": "The arterial supply of trachea is by", "exp": null, "cop": 3, "opa": "Bronchial artery", "opb": "Tracheal artery", "opc": "Inferior thyroid artery", "opd": "Superior thyroid artery", "subject_name": "Anatomy", "topic_name": null, "id": "4dc11f5e-d93f-48cc-ac67-0f40ea872092", "choice_type": "single"} {"question": "Inner ear fully developed at", "exp": "Ans. is 'c' i.e., 20 weeksDevelopment of membranous internal ear is completed by 10\" weeks and reaches its adult size and shape by 20-22 weeks when the cochlea is developed sufficiently.", "cop": 3, "opa": "4 weeks", "opb": "10 weeks", "opc": "20 weeks", "opd": "32 weeks", "subject_name": "Anatomy", "topic_name": null, "id": "1f9556f8-ba17-44d9-911f-8d2802cef5bb", "choice_type": "single"} {"question": "Structure passing through anterior pa of jugular foramen", "exp": "Jugular foramen transmits Through anterior pa: 1. Inferior petrosal sinus 2. Meningeal branch of the ascending pharyngeal aery Notes: through the middle pa: 9th, 10th,11th cranial nerves Through the posterior pa: internal jugular vein and meningeal branch of the occipital aery. BDC 6th edition vol 3 page no:20", "cop": 1, "opa": "Inf petrosal sinus", "opb": "Internal jugular vein", "opc": "Internal jugular vein", "opd": "X, XI nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9a46bc3d-6b29-40de-aef8-1db8aca4306d", "choice_type": "single"} {"question": "Bennet's Fracture involves", "exp": "Fracture of the base of the first metacarpal is called Bennett&;s fracture.It involves the anterior pa of the base, and is caused by a force along its long axis. The thumb is forced into a semiflexed position and cannot be opposed. The fist cannot be clenchedReference: Vishram Singh Anatomy; 2nd edition; Page no: 32", "cop": 1, "opa": "Base of Ist metacarpal", "opb": "Neck of Ist metacarpal", "opc": "Base of Vth metacarpal", "opd": "Neck of Vth metacarpal", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "5e36706e-d70f-4cea-9f3f-cad3d41c3ba9", "choice_type": "single"} {"question": "Middle segment pancreatectomy avoided in", "exp": "Middle or central or segmental pancreatectomy Middle pancreatectomy is a safe, effective procedure for treatment of benign and low grade malignant neoplasm of the mid pancreas Advantages of Middle or Segmental Pancreatectomy Preserves pancreatic parenchyma Reduces the risk of exocrine and endocrine insufficiency. Consists of a limited resection of the mid poion of the pancreas. Indications of Middle or segmental Pancreatectomy Benign or low grade malignant tumor Location in the neck or its contiguous poion A distal pancreas stump of at least 5cm in length. Ref: Blumga 5th edition Pgno :959-960", "cop": 2, "opa": "Cystadenoma", "opb": "Tumors of head pancreas", "opc": "Tumors of tail of pancreas", "opd": "Tumors of neck of pancreas", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1178ac81-7621-49cd-b539-e99787992e85", "choice_type": "single"} {"question": "Artery not involved in Vascular anastemosis around Acromian", "exp": "Acromial Branch of Thyrocervical Trunk (Branch of 1st part of Subclavian artery).\nAcromial Branch of Thoracoacromial trunk (Branch of 2nd part of Axillary artery).\nAcromial branch of  posterior circumflex humeral artery form anastomosis around Acromian.", "cop": 3, "opa": "Thyrocervical Trunk", "opb": "Thoracoacromial trunk", "opc": "Anterior circumflex humeral artery", "opd": "Posterior circumflex humeral artery", "subject_name": "Anatomy", "topic_name": null, "id": "a28f17b3-81df-432b-a85f-fa1bf779475e", "choice_type": "single"} {"question": "Caseous granuloma is seen in", "exp": "ref Robbins 8/e p718 from tuberculous lesions often contain caseous , , other , and contain epithelioid cells, a few lymphocytes, and occasional multinucleated giant cells. No necrosis is seen. Granulomas following are noncaseous and characterized by epithelioid cell reaction with giant cells and , and the is based on finding organisms or and mononuclear macrophages when examined under polarized light. The crystals are composed of hydrous Fungal infections Most Histoplasma capsulatum. The granulomas are often isolated or small and scattered, thereby resembling miliary granulomas. The organism can be identified histologically. They are intracellular organisms, with 1-5 mm, round to oval yeast-like bodies, with a small, central round nucleus. Periodic acid-Schiff (PAS) and methenamine-silver (Meth-Ag) stains highlight these organisms. Other fungi that may cause granulomas are Cryptococcus neoformans (Fig. 21.4A), Blastomyces Fig. 21.4B), Mucorales, causing Fig. 21.4C), and Coccidioides immitis.13Some of these organisms are associated with definite geographical regions. Because of the ease of travel, however, diseases do not necessarily present in a Fungal infections Most Histoplasma capsulatum. The granulomas are often isolated or small and scattered, thereby resembling miliary granulomas. The organism can be identified histologically. They are intracellular organisms, with 1-5 mm, round to oval yeast-like bodies, with a small, central round nucleus. Periodic acid-Schiff (PAS) and methenamine-silver (Meth-Ag) stains highlight these organisms. Other fungi that may cause granulomas are Cryptococcus neoformans (Fig. 21.4A), Blastomyces (Fig. 21.4B), Mucorales, causing Fig. 21.4C), and Coccidioides immitis.13Some of these organisms are associated with definite geographical regions. Because of the ease of travel, however, diseases do not necessarily present in a ", "cop": 1, "opa": "Histoplasmosis", "opb": "Silicosis", "opc": "Sarcoidosis", "opd": "Foreign body", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9102efdb-b74b-4cba-a4e4-32f355b81c43", "choice_type": "single"} {"question": "Heterotrophic calcification occurs in", "exp": "Ref Robbins 7/e p 41_42, Harrison 17/e p1952 Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. The acquired form of HO most frequently is seen with either musculoskeletal trauma, spinal cord injury, or central nervous system injury. For example, patients who have recently undergone total hip ahroplasty or have paraplegia after spinal cord injury are at risk for HO. The fever, swelling, erythema, and occasional joint tenderness seen in early HO can be difficult to distinguish from cellulitis, osteomyelitis, or thrombophlebitis. Bone scanning and other imaging tests frequently are used to distinguish between these diagnostic possibilities", "cop": 1, "opa": "Ankylosing spondylitis", "opb": "Rieter's syndrome", "opc": "Forrestier disease", "opd": "Rheumatic ahritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "16257977-c123-4d14-9462-b85e4bd791ca", "choice_type": "single"} {"question": "Most common complication of pseudocyst", "exp": "Pseudocyst complications Infection (MC) :14% Pain due to expansion Hemorrhage upto 10% Duodenal obstruction Rupture Abscess Ref: Shackelford 7th edition Pgno :1159", "cop": 1, "opa": "Infection", "opb": "Rupture", "opc": "Hemorrhage", "opd": "Compression", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "633ecdcb-f81d-4390-b223-7330e2ca82e9", "choice_type": "single"} {"question": "Harelip Is due to non fusion of", "exp": null, "cop": 3, "opa": "Medial nasal process with lateral nasal process", "opb": "Lateral nasal process with maxillary process", "opc": "Medial nasal process with maxillary process", "opd": "Lateral nasal process with palatal process", "subject_name": "Anatomy", "topic_name": null, "id": "8cae82b0-3bab-474c-8328-c1303197f703", "choice_type": "single"} {"question": "Passavants ridge is formed by", "exp": "Some of the upper fibres of the palatopharyngeus pass circularly deep to the mucous membrane of the pharynx and form a sphincter internal to the superior constrictor. These fibres constitute Passavant's muscle which on contraction raises a ridge called the Passavant's ridge on the posterior wall of the nasopharynx. When the soft palate is elevated it comes in contact with this ridge, the two together closing the pharyngeal isthmus between the nasopharynx and the oropharynx. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 4, "opa": "Palatoglossus", "opb": "Superior constrictor", "opc": "Salpingopharyngeus", "opd": "Palatopharyngeus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "2683be5e-7bb5-4bf7-aba3-4f5e7b7eec3d", "choice_type": "single"} {"question": "First pharyngeal arch derivative is", "exp": "(A) Maxillary artery ArchNerve of ArchMuscles of ArchFirstMandibularMedial and lateral pterygoidsMasseter, Temporalis, MylohyoidAnt. belly of Digastric Tensor tympani, Tensor palatiSecondFacialMuscles of face, Occipito-frontalis Platysma, Stylohyoid, Post, belly of Digastric, Stapedius, Auricular musclesThirdGlossopharyngealStylopharyngeusFourthSuperior laryngealCricothyroidSixthRecurrent laryngealMuscles of larynx", "cop": 1, "opa": "Maxillary artery", "opb": "Stylohyoid ligament", "opc": "Styloid process", "opd": "Posterior 1/3rd of tongue", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "d97a736e-a4ed-4b91-90c4-66b4eef7667d", "choice_type": "single"} {"question": "Pretrematic nerve of 1st pharyngeal arch is", "exp": "Pharyngeal Arch Nerves: Nerve of 1st arch - Mandibular division of trigeminal nerve Pretrematic nerve - Chorda tympani & greater petrosal nerves (purely sensory) of facial nerve. Nerve of 2nd arch - Facial nerve Pretrematic nerve - Tympanic branch of glossopharyngeal nerve. Nerve of 3rd arch - Glossopharyngeal nerve Pretrematic nerve - auricular branch of vagus nerve Nerve of 4th arch - Pharyngeal branch of vagus nerve Nerve of 6th arch - Recurrent laryngeal branch of vagus nerve.", "cop": 3, "opa": "Vagus nerve", "opb": "Glossopharyngeal", "opc": "Chorda tympani", "opd": "Trigeminal", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 3", "id": "bb51279c-d947-4f64-be87-5c3ca9d209fa", "choice_type": "single"} {"question": "Origin of ovary is from", "exp": "C. i.e. Genital ridge", "cop": 3, "opa": "Wolffian duct", "opb": "Genital duct", "opc": "Genital ridge", "opd": "Genital tubercle", "subject_name": "Anatomy", "topic_name": null, "id": "b8806459-f7a0-4554-850a-2b02c25fcfaf", "choice_type": "single"} {"question": "Auditory pathway passes through", "exp": null, "cop": 1, "opa": "Medial geniculate body", "opb": "Lateral geniculate body", "opc": "Reciculate formation", "opd": "Cerebellar fornix", "subject_name": "Anatomy", "topic_name": null, "id": "21e4d5c3-f9d5-421a-a0ad-2d3d001055ec", "choice_type": "single"} {"question": "Normal Carrying Angle", "exp": "Carrying angle is a small degree of cubitus valgus, formed between the axis of a radially deted forearm and the axis of the humerus. It helps the arms to swing without hitting the hips while walking.Normally it is 5-15o away from the body.Ref: Vishram Singh; Volume 1; II edition; Page no: 130", "cop": 2, "opa": "5-10degrees", "opb": "5-15degrees", "opc": "10-20degrees", "opd": "15-20degrees", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a58c5208-d8dc-4a1a-a2e2-b99d2e847ca9", "choice_type": "single"} {"question": "Best blood product to be given in a patient of multiple clotting factor deficiency with active bleeding", "exp": "Refer Robbins page no 664", "cop": 1, "opa": "Fresh frozen plasma", "opb": "Whole blood", "opc": "Packed RBCs", "opd": "Cryoprecipitate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6b6102d0-696c-4a9a-828a-88323754d9e7", "choice_type": "single"} {"question": "Boundary of the Koch's triangle is not formed by", "exp": "The atrioventricular node (AVN) is within the subendocardial layer of the hea wall of the interatrial septum. In relation to the right atrium, its position is within the triangle of Koch Triangle of Koch: a roughly triangular area on the septal wall of the right atrium, bounded by the base of the septal leaflet of the tricuspid valve, the anteromedial margin of the orifice of the coronary sinus, and the tendon of Todaro; it marks the site of the atrioventricular node. Tendon of Todaro: A palpable subendocardial collagen bundle in the wall of the right atrium, extending from the central fibrous body (fibrous skeleton of hea) across the torus aoicus toward the medial extremity of the valve of the inferior vena cava. Ref - pubmed.com", "cop": 4, "opa": "Tricuspid valve ring", "opb": "Coronary sinus", "opc": "Tendon of todaro", "opd": "Limbus fossa ovalis", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "97810d2a-6210-4c02-abb6-683138bc5dc3", "choice_type": "single"} {"question": "The facial artery terminates in the anastomosis with", "exp": "D. i.e. (Branch of the ophthalmic artery) (57-58-BDC 3rd)* FACIAL - ARTERY - Branch of the external carotid artery*** It lies deep to the sub mandibular salivary gland and emerges and bends around the lower border of the mandible. It then ascends over the face close to the anterior border of the masseter muscle. The artery then ascends around the lateral margin of the mouth and terminates at the medial angle of the eye by anastomosing with the dorsal nasal branch of the ophthalmic artery.", "cop": 4, "opa": "Opposite side of the facial artery", "opb": "Transverse facial artery", "opc": "Anastomosis with Infra orbital artery", "opd": "Branch of the ophthalmic artery", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "6cdf13d5-119f-45a4-91f9-f6454bc951f1", "choice_type": "single"} {"question": "Folate trap occurs due to the deficiency of", "exp": "The conversion of 5,10-methylene-THF into 5-methyl-THF is irreversible. The only way to make fuher use of 5-methyl-THF and to maintain the folate cycle is by the vitamin B12-dependent remethylation of homocysteine to methionine (regenerating THF). The methyl group transfer is therefore greatly dependent on 5-methylTHF and the availability of Vitamin-B12. In cases of vitamin-B12 deficiency, an intracellular deficiency of biologically active THF arises as methyl-THF is not conveed to THF and the folate gets trapped as methyl-THF. This situation is called a 'folate trap' (or methyl group trap). Reference: Harpers illustrated biochemistry 30th edition", "cop": 4, "opa": "Thiamine", "opb": "Biotin", "opc": "Folic acid", "opd": "vitamin B12", "subject_name": "Anatomy", "topic_name": null, "id": "51da5b72-95db-4963-abc2-1845ac902ccc", "choice_type": "single"} {"question": "Facial artery gives rise to following branches", "exp": "Facial artery gives rise to :\n\nSubmental artery.\nTonsillar artery.\nAscending palatine artery.\nGlandular artery.\nSuperior and inferior labial artery.\nLateral nasal artery.\nAngular artery.", "cop": 2, "opa": "Submental artery, ascending pharyngeal artery, tonsillar artery, posterior auricular artery", "opb": "Submental artery, ascending palatine artery, tonsillar artery, angular artery", "opc": "Tonsillar artery, submental artery, ascending pharyngeal artery, angular artery", "opd": "Tonsillar artery, submental artery, ascending pharyngeal artery, glandular artery", "subject_name": "Anatomy", "topic_name": null, "id": "7d7beced-929b-4565-a965-9cc9e871d69f", "choice_type": "single"} {"question": "Inferior epigastric vein drains into", "exp": "The inferior epigastric aery - It arises from the external iliac aery near its lower end just above the inguinal ligament. It runs upwards and medially in the extraperitoneal connective tissue, passes just medial to the deep inguinal ring, pierces the fascial transversalis at the lateral border of the rectus abdominis and enters the rectus sheath by passing in front of the arcuate line .Within the sheath it supplies the rectus muscle and ends by anastomosing with the superior epigastric aery. branches of inferior epigastric aery - (a) A cremasteric branch - To the spermatic cord, or the aery of the round ligament in females; (b) A pubic branch - Which anastomoses with the pubic branch of the obturator aery; (c) muscuiarbranches - To the rectus abdominis , and (d) cutaneous branches - To the overlying skin. Ref : B D Chaurasia's Human Anatomy , seventh edition, volume 2 , pg. no. 229", "cop": 2, "opa": "Femoral vein", "opb": "External iliac vein", "opc": "Internal iliac vein", "opd": "Internal pudendal vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "eaea1666-a06d-4e30-bc3e-8baf6a1d6d52", "choice_type": "single"} {"question": "HLA typing is useful in", "exp": "Also used in organ transplant Ref Robbins 9/e p195 ,215 DNA paternity testing is the use of DNA profiles to determine whether an individual is the biologicalparent of another individual. Paternity testing can be especially impoant when the rights and duties of the father are in issue and a child's paternity is in doubt. Tests can also determine the likelihood of someone being a biological grandparent. Though genetic testing is the most reliable standard, older methods also exist, including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen antigens. The current techniques for paternity testing are using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). Paternity testing can now also be performed while the woman is still pregnant from a blood drawn", "cop": 1, "opa": "Disputed paternity", "opb": "Thanotology", "opc": "Organ transplant", "opd": "Dactylography", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c48969cd-8d23-4dd0-a438-1d8ad27d4a7e", "choice_type": "single"} {"question": "If the 3rd supralabial scales are large and touching the eye and nasal shield, the snake may be", "exp": "If the head scales are large, it may be poisonous or non poisonous. Look for the 3rd supra labial and if it is touching the eye and the nasal shield, it is poisonous (cobra or coral snake) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 511", "cop": 4, "opa": "Krait", "opb": "Pit viper", "opc": "Saw scaled viper", "opd": "Cobra", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "029e5bd6-8261-4a85-a0f1-dae4e62c0b43", "choice_type": "single"} {"question": "The preganglionic parasympathetic fibres to the parotid gland travel in", "exp": "The preganglionic fibres begin in the inferior salivatory nucleus; pass through the glossopharyngeal nerve, it's tympanic beach, the tympanic plexus and the lesser petrosal nerve and relay in the price ganglion. The postganglionic fibres pass through the auriculotemporal nerve and reach the gland. Ref: BDC 6th edition pg 110 Notes: Ref flow cha 5.1 pg 111 BDC 6th edition", "cop": 1, "opa": "Lesser petrosal nerve", "opb": "Greater petrosal nerve", "opc": "Deep petrosal nerve", "opd": "Internal carotid nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1be7901f-9c9b-4064-b332-9536346f77cd", "choice_type": "single"} {"question": "The mass treatment of trachoma is undeaken if the prevalence in community is", "exp": "Mass treatment of trachomaA prevalence of more than 5 %; severe and moderate trachoma in children under 10 years Treatment consists of an application of twice daily of tetracycline 1 % ointment to all children, for 5 consecutive days each month or once daily for 10 days each month for 6 consecutive months.Alternative antibiotic - erythromycin(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 326, 327)", "cop": 2, "opa": "3%", "opb": "5%", "opc": "6%", "opd": "10%", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ed6cfae9-7def-4fd1-8da8-bce4a09b7346", "choice_type": "single"} {"question": "Organ of Rosenmullar is remenant of", "exp": "Ans. is 'c' i.e., Mesonephric tuble", "cop": 3, "opa": "Endodermal sinus", "opb": "Mulleria duct", "opc": "Mesonephric tuble", "opd": "Paramesonephric duct", "subject_name": "Anatomy", "topic_name": null, "id": "ccf15025-2d65-4cf1-8966-1d1f73c2545e", "choice_type": "single"} {"question": "Most common site of metastasis in cholangiocarcinoma", "exp": "Distant metastasis occurs in one third of patients Most common site is liver, lung or mediastinum, peritoneum Ref: Sabiston 20th edition Pgno :1514-1518", "cop": 1, "opa": "Liver", "opb": "Bones", "opc": "Lung", "opd": "Pancreas", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "60b2f968-6f74-4870-b872-6ed22356a4f2", "choice_type": "single"} {"question": "Commonest cause of pyogenic liver abscess", "exp": "Hematogenous spread is most common among given option", "cop": 2, "opa": "Aspiration", "opb": "Hematogenous spread from a distant site", "opc": "Direct contact", "opd": "Lymphatic spread", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "19980104-6bcf-415f-a9c4-5b8b5ef6adee", "choice_type": "single"} {"question": "Varicocele is common on left testis because", "exp": "Variocele formation has been attributed to one of the three primary factors : Increased venous pressure in left renal vein Collateral venous anastomoses Absent or incompetent valves in the internal spermatic vein. Ref : Bailey & Love 23/e p1273", "cop": 2, "opa": "Left testicular vein drains into IVC which has high pressure", "opb": "Left testicular vein drains into left renal vein which has high pressure", "opc": "Left testis is lower situated", "opd": "Compression of testicular vein by rectum", "subject_name": "Anatomy", "topic_name": "Urology", "id": "8fd061b2-ce3b-4cb8-90e7-ac5ae27bf974", "choice_type": "single"} {"question": "Level of lower border of lung at mid axillary line is", "exp": "B i.e. 8th rib", "cop": 2, "opa": "6th rib", "opb": "8th rib", "opc": "10th rib", "opd": "12th rib", "subject_name": "Anatomy", "topic_name": null, "id": "e6d0585a-5853-4ccc-87ed-a6daa5855cc2", "choice_type": "single"} {"question": "Diarthrosis is known as", "exp": null, "cop": 1, "opa": "Synovial joint", "opb": "Suture", "opc": "Symphysis pubis", "opd": "Gomphosis", "subject_name": "Anatomy", "topic_name": null, "id": "4b478e6e-6274-4c88-a591-3d341bfa269e", "choice_type": "single"} {"question": "Treatment of choice in acute sarcoidosis is", "exp": "For acute disease, no therapy remains a ble option for patients with no or mild symptoms. For symptoms confined to only one organ, topical therapy is preferable. For multiorgan disease or disease too extensive for topical therapy, an approach to systemic therapy is outlined. Glucocoicoids remain the drugs of choice for this disease. However, the decision to continue to treat with glucocoicoids or to add steroid-sparing agents depends on the tolerability, duration, and dosage of glucocoicoids. Ref Harrison 19th edition pg 2210", "cop": 1, "opa": "Prednisolone", "opb": "Cyclosporine", "opc": "Infliximab", "opd": "IV Immunoglobulins", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "289f9cbf-3290-4226-abd5-19a7d9d438ab", "choice_type": "single"} {"question": "In pyogenic liver abscess commonest route of spread", "exp": "\"Along with cryptogenic infections, infections from the biliary tree are presently the most common identifiable cause of the hepatic abscess. Biliary obstruction results in bile stasis, with the potential for subsequent bacterial colonization, infection and ascension into the liver. This process is k/a ascending suppurative cholangitis. The nature of biliary obstruction is mostly related to stone disease or malignancy. In Asia, intrahepatic stones and cholangitis (recurrent pyogenic cholangitis) is a common cause, whereas, in the Western world, malignant obstruction is becoming a more predominant factor\" Ref : Sabiston 18/e p1485", "cop": 2, "opa": "Hematogenous through poal vein.", "opb": "Ascending infection through biliary tract", "opc": "Hepatic aery", "opd": "Local spread", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "29ff1468-bf9c-442f-81b9-ab7524e294be", "choice_type": "single"} {"question": "Maintenance dose rate of drug depends primarily on", "exp": "Ref-KDT 6/e p34 Maintenance dose is determined by clearance Maintenance dose=CLxPlasma concentration required", "cop": 4, "opa": "Volume of distrubtion", "opb": "Half life", "opc": "Lipid solubility", "opd": "Total body clearance", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "58ef2bbc-dded-4acb-b573-51545a85f669", "choice_type": "single"} {"question": "Diagnosis of x linked agammaglobulinamia should be suspected if", "exp": "Ref Robbins 9/e p240-241 Classically, this disease is characterized by the following: * Absent or markedly decreased numbers of B cells in the circulation, with depressed serum levels of all classes of immunoglobulins. The numbers of pre-B cells in the bone marrow may be normal or reduced. * Underdeveloped or rudimentary germinal centers in peripheral lymphoid tissues, including lymph nodes, Peyer patches, the appendix, and tonsils * Absence of plasma cells throughout the body * Normal T cell-mediated responses", "cop": 1, "opa": "Absent tonsils and no palpable lymph nodes on physical examination", "opb": "Female sex", "opc": "High iso hemagglutinin titers", "opd": "Low CD3", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cb41f1e7-911c-4dd9-949f-a27bbb6098d5", "choice_type": "single"} {"question": "Muscle forming anterior and posterior faucial folds of tonsillar fossa, respectively", "exp": "Palatoglossus-palatopharyngeus form the boundary of the tonsillar fossaReference: Chaurasia; 6th edition", "cop": 2, "opa": "Levator veli palatine-tensor veli palatine", "opb": "Palatoglossus-palatopharyngeus", "opc": "Palatopharyngeus-salpingopharyngeus", "opd": "Styloglossus-stylopharyngeus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "7ba37a39-49dd-412d-a945-49fa3d17ceaf", "choice_type": "single"} {"question": "Difference between typical cervical & thoracic veebral", "exp": "B i.e., Has a foramen transversorium", "cop": 2, "opa": "Has a triangular body", "opb": "Has a foramen transversarium", "opc": "Superior aicular facet directed backwards & upwards", "opd": "Has a large veebral body", "subject_name": "Anatomy", "topic_name": null, "id": "425741f5-1bac-4c64-9b43-078fac25f6b4", "choice_type": "single"} {"question": "Content of the star marked triangle", "exp": "Marked triangle - Anatomical snuff box Anatomical snuff box -Content - radial aery -Boundaries Anterolaterally - abductor pollicis longus and extensor policis brevis Posteromedially- extensor pollicis longus Floor-styloid process, scaphoid,trapezium Floor-Carpetted by tendons of ECRL,ECRB Roof-Cephalic vein ,Sup. branch of radial nerve", "cop": 2, "opa": "Basilic vein and superficial branch of radial nerve", "opb": "Radial aery only", "opc": "Radial aery and Posterior interosseous nerve(PIN)", "opd": "Cephalic vein and Posterior interosseous nerve(PIN)", "subject_name": "Anatomy", "topic_name": "Muscles of arm and forearm region & Cubital fossa", "id": "45bfe7c1-cf3a-420c-8783-b5a72e248814", "choice_type": "single"} {"question": "Frontal eye field Area is", "exp": "Frontal eye field ( Area 8): Located in middle frontal gyrus in front of premotor area Conjugate detion of eyes to opposite side. Destructive lesions result in eyes looking towards the side of lesion.", "cop": 3, "opa": "4", "opb": "6", "opc": "8", "opd": "41", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9faa8b21-c39f-4b7d-98ff-9885d6a9651c", "choice_type": "single"} {"question": "Subarachnoid space ends at", "exp": "The dura and arachnoid along with the subarachnoid space containing CSF extend up to 2nd sacral veebra. Below the lower border of L1 and S2 veebrae, the subarachnoid space contains 40 spinal nerve roots of L2-L5, S1-S5 and Co 1 which constitute the cauda equina. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3.", "cop": 4, "opa": "D12", "opb": "L2", "opc": "L5", "opd": "S2", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9ce7e92d-747c-42ab-86e5-6332ab52e1fb", "choice_type": "single"} {"question": "Anemia in chronic renal failure is due to", "exp": "Ref Harrison 19 th ed pg 630 The anemia is primarily due to a failure of EPO production by the diseased kidney and a reduction in red cell survival. In ceain forms of acute renal failure, the correlation between the anemia and renal function is weaker. Patients with the hemolytic-uremic syndrome increase eryth- ropoiesis in response to the hemolysis, despite renal failure requiring dialysis.", "cop": 1, "opa": "Decreased erythropoietin production", "opb": "Iron deficiency", "opc": "Hypoplastic bone marrow", "opd": "Decreased folate levels", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "326dff05-eb4e-403b-8449-136265f44e71", "choice_type": "single"} {"question": "mood stablizer used in the management of drug induced neutropenia", "exp": "- Lithium has a narrow therapeutic index - GIT == diarrhea, vomiting - NEUROLOGICAL=== tremor, co ordination - Therapeutic level is 0.8-1.2meq/l - HEMODIALYSIS is the TOC for lithium toxicity - OTHER USES - Anti- suicidal propey, used to prevent suicide. - Correct drug induced neutropenia. ref, kaplon and sadock, synopsis of psychiatry, 11 thh edition, pg no. 935", "cop": 1, "opa": "lithium", "opb": "valproate", "opc": "carbamezepine", "opd": "lamotrigine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "57a17cad-047d-4acc-9f9a-4dab708ed297", "choice_type": "single"} {"question": "Epithelium of cervix mucosa is lined by", "exp": "Other epithelia: Simple squamous epithelium lines free surface of serous pericardium, pleura & peritoneum (here it is called mesothelium) lines inside hea a endocardium a blood vessels & lymphatics a endothelium etc. Stratified squamous epithelium: 1. keratinized ??' lines skin of whole body & forms epidermis. 2. non keratinized ??'seen in lining of mouth, tongue, pharynx, esophagus, vagina, cornea etc. Simple columnar epithelium ??' (Non cilia / microvilli) present over mucous membrane of stomach & large intestine. Ciliated columnar epithelium ??' Respiratory tract, uterus, uterine tubes, efferent ductules of testes, pas of middle ear & auditory tube, ependyma lining the central canal of spinal cord & ventricles of brain. Pseudostratified columnar epithelium ??' some pas of auditory tube, ductus deferens, male urethra (membranous & penile pas), trachea & large bronchi", "cop": 2, "opa": "Simple squamous epithelium", "opb": "Simple columnar epithelium", "opc": "Stratified squamous epithelium", "opd": "Ciliated columnar epithelium", "subject_name": "Anatomy", "topic_name": "DNB 2018", "id": "d4780c9d-f96b-4143-ab78-a258a567a06d", "choice_type": "single"} {"question": "Double aoa develops from", "exp": "Inderbir Singh&;s Human embryology Tenth edition Pg 257Double aoa occurs due to the persistence of distal poion of the right dorsal aoa", "cop": 3, "opa": "1st arch aery", "opb": "2nd arch aery", "opc": "Right dorsal aoa", "opd": "Left dorsal aoa", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fe2ba919-ff2e-43c2-b9f0-afc8696cfec9", "choice_type": "single"} {"question": "Protractor of scapula", "exp": "Protraction of the scapula (as in pushing and punching movements). It is brought about by the serratus anterior and by the pectoralis minor. It is associated with forward movements of the lateral end and backward movement of the medial end of the clavicle . Ref - BDC 6th e p142", "cop": 1, "opa": "Serratus anterior", "opb": "Rhomboidis major", "opc": "Deltoid", "opd": "Pectoralis major", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "439163ee-0cd6-41ab-8a66-b1c5e5aea0d9", "choice_type": "single"} {"question": "Downward displacement of enlarged spleen is prevented by", "exp": "Phrenicocolic ligament and left colic flexure prevent downward displacement of enlarged spleen.", "cop": 2, "opa": "Lienorenal ligament", "opb": "Phrenicolic ligament", "opc": "Upper pole of right kidney", "opd": "Sigmoid colon", "subject_name": "Anatomy", "topic_name": null, "id": "fe13cafa-4af3-42b0-8008-e265087e3d0c", "choice_type": "single"} {"question": "The optimal position of the ankle to avoid ankylosis is", "exp": "The optimal position of the ankle to avoid ankylosis is one of slight plantar flexion.Ref: Chaurasia; Volume 2; 6th edition; Page no: 150", "cop": 1, "opa": "Slight plantar flexion", "opb": "Slight plantar extension", "opc": "Slight dorsiflexion", "opd": "Slight inversion", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dca96f1e-103a-4993-a66d-f0e14ad22b57", "choice_type": "single"} {"question": "Meckel&;s cave is related to", "exp": "The trigeminal ganglion lies on the trigeminal impression,on the anterior surface of the petrous temporal bone near its apex.It occupies a special space of duramater,called the trigeminal or Meckel's cave. REF.BDC VOL.3,Fifth edition.", "cop": 3, "opa": "Submandibular gland", "opb": "Trigeminal ganglion", "opc": "Trigeminal ganglion", "opd": "Ptergopalatine ganglion", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "a72e21f3-c7fe-4ee2-8384-6a73c326c2e4", "choice_type": "single"} {"question": "The structure present anterior to transverse pericardial sinus is", "exp": "Transverse sinus is a horizontal gap between the aerial and venous ends of the hea tube, it is bound Anteriorly: ascending aoa, pulmonary trunk Posteriorly: SVC Inferiorly: L. atrium On each side it opens into the general pericardial cavity. Oblique sinus is a narrow gap behind the hea. It is bound anteriorly : L. atrium posteriorly: R. parietal pericardium, oesophagus.", "cop": 3, "opa": "Inferior vena cava", "opb": "Superior vena cava", "opc": "Aoa", "opd": "Pulmonary aery", "subject_name": "Anatomy", "topic_name": "CVS Embryology", "id": "84545478-fafa-455d-84ab-c21968cecb78", "choice_type": "single"} {"question": "The mucosa of the posterior third of the tongue is supplied by", "exp": null, "cop": 4, "opa": "Facial nerve", "opb": "Trigeminal nerve", "opc": "Mandibular nerve", "opd": "Glossopharyngeal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "62b2dd42-14ba-4f13-9f0c-8d161389e6bb", "choice_type": "single"} {"question": "Onion skin fibrosis of the common bile duct is", "exp": "Refer Robbins page no Pg 860 MORPHOLOGY Morphologic changes differ between the large ducts (intrahe- patic and extrahepatic) and the smaller intrahepatic ducts. Large duct inflammation is similar to that seen in ulcerative colitis: acute, neutrophilic infiltration of the epithelium superim- posed on a chronic inflammatory background. Inflamed areas develop strictures because edema and inflammation narrows the lumen or because of subsequent scarring. The smaller ducts, however, often have little inflammation and show a strik- ing circumferential \"onion skin\" fibrosis around an increas- ingly atrophic duct lumen (Fig. 18-39), eventually leading to obliteration by a \"tombstone\" scar. Because the likelihood of sampling smaller duct lesions on a random needle biopsy is miniscule, diagnosis depends on radiologic imaging of the extrahepatic and larger intrahepatic ducts. As the disease pro- gresses the liver becomes markedly cholestatic, culminating in biliary cirrhosis much like that seen with chronic obstruction and primary biliary cirrhosis. Biliary intraepithelial neoplasia may develop and cholangiocarcinoma appears usually with a fatal outcomes.", "cop": 2, "opa": "Primary biliary cirrhosis", "opb": "Primary sclerosisg cholangitis", "opc": "Extrahepatic biliary fibrosis", "opd": "Congenital hepatic fibrosis", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "e6dd1fd5-3a0d-4405-9f9d-f815844895d8", "choice_type": "single"} {"question": "Left posterior sector of liver consists of", "exp": "Lobar anatomy of the liver Liver is divided into two lobes by the main poal fissure (Scissura), known as Cantlie's line Cantlie's line describes a 75deg angle with a horizontal plane It extends from the gallbladder fossa to the left side of the IVC Right and left halves of the liver is delineated by a plane through the MHV and IVC Right poal fissure divides the right lobe into an anteromedial and posterolateral sector. RHV courses along this fissure Right poal fissure describes an angle of 40deg with the transverse plane. Left poal fissure divides the left lobe into an anterior and posterior sector, LHV courses along this fissure In the right lobe Anteromedial sector : Segment V anteriorly and segment VIII posteriorly Posterolateral sector : Segment VI anteriorly and segment VII posteriorly In the left lobe Anterior sector is divided by the umbilical fissure into segment IV and segment III Posterior sector is comprised of only one segment, segment II Umbilical fissure is not a Scissura, does not contain a hepatic vein, but contains the left poal triad. Left Scissura runs posterior to the ligament I'm teres and contains the LHV; the left liver is split into an anterior (segments III and IV) and posterior (segment II- the only sector composed of a single segment) sector by the left Scissura. Ref: Sabiston 20th edition Pgno : 437-439", "cop": 2, "opa": "Segment II and III", "opb": "Segment II, III, IV", "opc": "Segment II only", "opd": "Segment I only", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "dfbe54ab-7def-4df6-bd41-d2429a628455", "choice_type": "single"} {"question": "Special visceral efferent doesn't include(2018)", "exp": "Special visceral efferent( purely motor) for the supply of muscles of facial expression, muscles of mastication and muscles of palate and pharynx, larynx(Nucleus ambiguous). Dorsal nucleus of vagus (parasympathetic): it is a mixed nucleus, being both motor (visceromotor and secretomotor) and sensory. General visceral efferent fibres arise in the dorsal nucleus of the vagus. Ref:- BD chaurasia volume 3, pg num:-288,289", "cop": 2, "opa": "A) nucleus ambiguous", "opb": "B) Dorsal nucleus of the Xth cranial nerve", "opc": "C) Motor nucleus of Vth cranial nerve", "opd": "D) Motor nucleus of VIIth cranial nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ab453b0b-2691-4bd3-9533-5c7605f48e8e", "choice_type": "single"} {"question": "In pyogenic liver abscess commonest route of spread is", "exp": "Routes of spread 1st most common - Biliary tract 2nd most common - poal vein", "cop": 2, "opa": "Hematogenous through poal vein", "opb": "Ascending infection through biliary tract", "opc": "Hepatic aery", "opd": "Local spread", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "422c1eb2-1a0e-4093-b8f8-65fd02fa8911", "choice_type": "single"} {"question": "Claw hand is caused by lesion of", "exp": "A greate than B Claw hand of 3rd bad 4th finger will be seen in isolated ulnar palsy as 1st ND 2nd fingers lumbricals are spared -----ulnar claw hand Claw hand of all fingers is seen in combined ulnar and median nerve palsy as all lumbricals and Interoosei are paralyzed -----true claw hand Refer ebnezar 4th/e p 336", "cop": 1, "opa": "Ulnar nerve", "opb": "Median nerve", "opc": "Axillary nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Peripheral nerve injuries", "id": "6311f1b5-5396-4b72-a72d-9f09987f3680", "choice_type": "single"} {"question": "Prostate gland is derived from", "exp": "In the hindgut at the region of cloaca develops a urogenital sinus which forms urinary bladder, urethra and lower pa of vagina in females. It also forms inner glandular poion of prostate gland. It is endodermal in origin.", "cop": 1, "opa": "Urogenital sinus", "opb": "Urogenital folds", "opc": "Labioscrotal swelling", "opd": "Gubernaculum", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "6d645d17-229e-490c-90fa-d7fa25230465", "choice_type": "single"} {"question": "In the testis, haploid number of chromosomes are present in", "exp": "Inderbir Singh's Human embryology; Tenth edition; Pg 20 Primary spermatocyte undergoes meiotic division to form secondary spermatocytes Each secondary spermatocyte divides to form two spermatids by a mitotic division which also contains a haploid number of chromosomes", "cop": 3, "opa": "Spermatogonia - Type A", "opb": "Primary spermatocyte", "opc": "Spermatids", "opd": "Spermatogonia - Type B", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b7f0eb9e-e158-4422-b256-495f4e3f322f", "choice_type": "single"} {"question": "Structure that does not cross the midline is", "exp": "Left gonadal vein, left suprarenal vein & right renal vein do not cross midline. Hemiazygos vein cross midline at The veebral level to join azygous vein. Left Renal vein is longer than right renal vein and cross midline anterior to aoa to drain into IVC. However, left gonadal & suprarenal veins drain into left renal vein (almost veically) without crossing midline. Ref: Gray's 39e/p1026", "cop": 1, "opa": "Left gonadal vein", "opb": "Left Renal vein", "opc": "Left brachiocephalic vein", "opd": "Hemiazygos vein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d01bb869-8284-4648-9ff0-629b1a420228", "choice_type": "single"} {"question": "Goblet cells are present in", "exp": "The lumen of the trachea is lined with mucous membrane that consists of a lining epithelium and an underlying layer of connective tissue. The lining epithelium is pseudostratified ciliated columnar. It contains numerous goblet cells and basal cells that lie next to the basement membrane.Ref: Inderbir Singh&;s Textbook of Human Histology; Pg No: 230", "cop": 1, "opa": "Trachea", "opb": "Jejunum", "opc": "Epididymis", "opd": "Ileum", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "86171a11-5793-4d64-916a-7305e7291302", "choice_type": "single"} {"question": "The number of symphyseal cartilages appearing during the development of mandible", "exp": null, "cop": 1, "opa": "Two", "opb": "Three", "opc": "Four", "opd": "One", "subject_name": "Anatomy", "topic_name": null, "id": "5e7f4420-7130-4313-9b1a-7a0dd9302780", "choice_type": "single"} {"question": "Pseudounipolar neurons are seen in", "exp": "Pseudounipolar neurons are actually unipolar to begin with but become bipolar functionally and are found in dorsal nerve root ganglia and sensory root ganglia of the cranial nerves. REF.B D Chaurasia's human anatomy,Vol 3,fifth edition,Pg.308", "cop": 4, "opa": "Celiac ganglion", "opb": "Olfactory", "opc": "Cochlea", "opd": "Spinal dorsal root ganglion", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "c86d1790-7a76-4d27-87b1-9ae0a4f82234", "choice_type": "single"} {"question": "percentage of moality in anorexia nervosa is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "75", "opb": "8", "opc": "45", "opd": "25", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "0a83ae10-7b6a-4596-b5d8-56a80264983c", "choice_type": "single"} {"question": "Lesion of medial temporal lobe is associated with", "exp": "A. i.e. Auditory amnesia", "cop": 1, "opa": "Auditory amnesia", "opb": "Agnosia", "opc": "Visual amnesia", "opd": "Alexia", "subject_name": "Anatomy", "topic_name": null, "id": "73cac3ac-357a-4f2b-b56e-7aaa8ae150ea", "choice_type": "single"} {"question": "any behaviour is assosiated with reward will be increased in frequency. this is based on", "exp": "Behavioral therapy is learning given by BF Skinner , according to him all behaviors are learned phenomenon and thus can be unlearned Positive reinforcement a type of reinforcement when a behavior is rewarded there is more chance that the behavior is repeated Negative reinforcement is that when a behavior is done and an aversive response is removed, the behavior is repeated. When I go and meet my girlfriend, she checks my messages and picks up fight (aversive response) suddenly I delete all messages one day and that day there was no fight (no aversive response) then that behavior is repeated (delete all messages before meeting my girlfriend) Extinction is the type of reinforcement where a behavior is done and a rewarding response is removed the chance is that behavior will not be repeated A child likes to play with children( reward) but when the child fights with other children( undesirable behavior) the child will be removed from playing( removing a reward) , then the child stops fighting with other children( reduction of undesirable behaviour) Ref. kaplon and sadock synopsis, 11 th edition, pg no. 845", "cop": 2, "opa": "mindfulness therapy", "opb": "behavior therapy", "opc": "psychodynamic therapy", "opd": "cognitive therapy", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "69242d81-7b89-40a5-97c2-000d69be583d", "choice_type": "single"} {"question": "Kupffer cells present in the adult liver are derived from", "exp": "Kupffer cells are actually macrophages and are derived from mesoderm. Hepatocytes and the epithelial lining of the intrahepatic biliary tree are derived from endoderm diveiculum of forgut.", "cop": 1, "opa": "Mesoderm", "opb": "Endoderm", "opc": "Ectoderm", "opd": "Neuroectoderm", "subject_name": "Anatomy", "topic_name": "Embryology and abdominal wall layer", "id": "ddc480d8-e7b1-45a8-8020-2729b5481bb2", "choice_type": "single"} {"question": "Commonest site of branchial cyst is", "exp": "Branchial cysts are characteristically found anterior and deep to the upper third of the sternocleidomastoid muscle. Branchial fistulas(those derived from 2nd branchial cleft) open externally in the lower third of necic, near the anterior border of sternocleidomastoid. Its internal orifice is located in the tonsillar fossa. Branchial cysts & fistulas are remnants of the branchial apparatus present in fetal life. branchial cysts, fistulas or sinuses are lined by squamous epithelium. Ref : Bailey & Love 25/e p727", "cop": 1, "opa": "Upper one third of SCM", "opb": "Lower one third of SCM", "opc": "Upper two third of the SCM", "opd": "Lower two third of the SCM", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6803f9cc-1464-4d32-8063-15dd3210d5fd", "choice_type": "single"} {"question": "Posterior cerebral aery supplies A/E", "exp": "Posterior cerebral aery supplies occipital, temporal, thalamus, lentiform nucleus, pineal, medial geniculate body, choroid plexus of inferior horn of lateral ventricle, 3rd ventricle, midbrain Ref: Gray's 40e/p-252", "cop": 1, "opa": "Pons", "opb": "Midbrain", "opc": "Thalmus", "opd": "Striate coex", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fbb2e44f-2736-42f9-8339-b4cb1c36c2fc", "choice_type": "single"} {"question": "Ligament of Berry in thyroid fixes", "exp": "(Cricoid Cartilage) (166-BDC-3)4th editionCapsules of Thyroid1. The true capsule is the peripheral condensation of the connective tissue of the gland2. The false capsule is derived from the pretracheal layer of the deep cervical fascia. It is thin along the posterior border of the lobes, but thick on the inner surface of the gland where it forms a suspensory ligament (of Berry). Which connects the lobe to the cricoid cartilage", "cop": 2, "opa": "Hyoid bone", "opb": "Cricoid cartilage", "opc": "Trachea", "opd": "Thyroid", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "a03d662a-f32a-4a87-93b1-3a1e1e5ec2e7", "choice_type": "single"} {"question": "If two buds of pancreas do not fuse, the anomaly is", "exp": "Pancreatic divisum is a congenital anomaly in the anatomy of the ducts of the pancreas in which a single pancreatic duct is not formed, but rather remains as two distinct dorsal and ventral ducts. imageref- researchgate.net", "cop": 2, "opa": "Ectopic pancreas", "opb": "Pancreatic divisum", "opc": "Annular pancreas", "opd": "Accessory pancreas", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "0e6d81ed-55d2-4ca7-b537-6b21f516a720", "choice_type": "single"} {"question": "The red velvety appearance of stomach mucosa is seen in the poisoning of", "exp": "(Refer: Rajesh Bardale - Principle of Forensic Medicine & Toxicology, 1 st edition, pg no: 430)", "cop": 2, "opa": "Lead", "opb": "Arsenic", "opc": "Copper", "opd": "Mercury", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "727efe5e-9b4f-4f4a-95c3-51b405e73c6a", "choice_type": "single"} {"question": "Paralysis of opponens muscle leads to loss of thumb....", "exp": "Flexion", "cop": 1, "opa": "Flexion", "opb": "Extension", "opc": "Pinching", "opd": "Abduction", "subject_name": "Anatomy", "topic_name": null, "id": "0f3bca72-df7b-45f3-a93b-e48d98d1e865", "choice_type": "single"} {"question": "Deja vu like experiences is seen epilepsies with their focus in", "exp": "Even though these phenomenon are seen in anxiety disorders and schizophrenia they are most characteristic of temporal lobe epilepsies", "cop": 3, "opa": "Diencephalon", "opb": "Orbitofrontal coex", "opc": "Temporal lobe", "opd": "Sensory motor cotex", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0c6b4599-61f9-40e2-8567-f2b0d6df5657", "choice_type": "single"} {"question": "Head of scapula is", "exp": "Lateral angle or glenoid angle is broad and bears the glenoid cavity or fossa, which is directed forwards, laterally and slightly upwards. Glenoid cavity margin gives attachment to the shoulder joint and to the glenoid labrum. BD Chaurasia 7th edition Page no: 9", "cop": 3, "opa": "Coracoid process", "opb": "Acromion process", "opc": "Lateral angle", "opd": "Spin", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "b709fcf2-76e0-4e22-a936-050bdc668f62", "choice_type": "single"} {"question": "HLA B27 is positive in", "exp": "Ref Robbins 8/e p193; Harrison 17/e p2051 ;9/e p215 The HLA complex, which is located on the sho arm of human chromosome 6, contains sequences encoding about 100 genes, most involved in the regulation of the immune response. HLA genes are classically grouped into three major classes.", "cop": 1, "opa": "Ankylosing spondylitis", "opb": "Rheumatoid ahritis", "opc": "SLE", "opd": "Behcet syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "36b1e3a9-5596-4992-8729-3b39ac3fd97b", "choice_type": "single"} {"question": "Nervus furcalis is another name for", "exp": "Nervus furcalis is another name for L 4", "cop": 1, "opa": "L4", "opb": "L5", "opc": "T6", "opd": "T4", "subject_name": "Anatomy", "topic_name": null, "id": "a7a24f52-2936-401b-a208-9e63bae13708", "choice_type": "single"} {"question": "The nerve roots blocked in pudendal nerve block is", "exp": "Pudendal nerve arises from S 2,3,4 roots", "cop": 3, "opa": "L1,2,3", "opb": "L 2,3", "opc": "S 2,3,4", "opd": "S4", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "27283a57-498e-4d60-957d-327a717ab934", "choice_type": "single"} {"question": "Lining epithelium of the uterine cavity is", "exp": "The endometrium, or mucosal lining of the uterus, is composed of a simple columnar epithelium and a lamina propria. The epithelium is composed of nonciliated secretory columnar cells and ciliated cells, whereas the lamina propria houses simple branched tubular glands that extend as far as the myometrium.Ref: Textbook of histology; 4th edition; Chapter 20; Female Reproductive System", "cop": 2, "opa": "Simple squamous epithelium", "opb": "Simple columnar epithelium", "opc": "Stratified squamous epithelium", "opd": "Ciliated columnar epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "62e8d00d-77f1-411d-90b6-d08dd9a002e5", "choice_type": "single"} {"question": "Dermatomal supply of the perianal skin is", "exp": "The Inferior rectal nerves (inferior anal nerves, inferior hemorrhoidal nerve) usually branch from the pudental nerve but occasionally arises directly from the sacral plexus; they cross the ischiorectal fossa along with the inferior hemorrhoidal vessels, toward the anal canal and the lower end of the rectum, and is distributed to the spincher ani externa and to the integument (skin) around the anus. image ref - Netter atlas", "cop": 4, "opa": "S1", "opb": "L2", "opc": "L3", "opd": "S4", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "73d8656b-3919-451d-aba2-7466370950c6", "choice_type": "single"} {"question": "Referred pain from knee to hip is due to", "exp": "Referred pain from knee to hip and vice-versa is due to Obturator nerve", "cop": 3, "opa": "Femoral Nerve", "opb": "Saphenous nerve", "opc": "Obturator nerve", "opd": "Accessory Obturator nerve", "subject_name": "Anatomy", "topic_name": null, "id": "838231ba-8ac5-48ee-98ab-957a0921073f", "choice_type": "single"} {"question": "The pacemaker potential is due to", "exp": ".", "cop": 2, "opa": "Fast Na+ channel", "opb": "Decrease in K+ permeability", "opc": "Slow Ca++ channel", "opd": "Rapid repolarization", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "064092b0-928b-44df-b714-eb6d926067a8", "choice_type": "single"} {"question": "Hunter&;s canal seen in", "exp": "ADDUCTOR/ HUNTER'S/ SUBSAORIAL CANAL - The adductor canal is an intermuscular space situated on the medial side of the middle one-third of the thigh Ref : B D Chaurasia's Human Anatomy , Seventh edition , volume 2, pg. no. 60 ( fig. no. 3.33 & 3.34 )", "cop": 3, "opa": "Cubital fossa", "opb": "Popliteal fossa", "opc": "Thigh", "opd": "Calf", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "115600f0-2b30-49c5-90d2-039ec53fa03d", "choice_type": "single"} {"question": "Largest bursa of the body is", "exp": "The iliopsaos bursa is the largest bursa of the human body and is bilaterally present in 98% of adults.", "cop": 1, "opa": "Ilio-psoas bursa", "opb": "Suprapatellar bursa", "opc": "Subcoracoid bursa", "opd": "Olecranon bursa", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "4c6a0f81-802d-4169-8ef7-c018bd3f4f5e", "choice_type": "single"} {"question": "In cholangitis, the organism mostly responsible is", "exp": "Ascending bacterial infection of the biliary ductal system with obstruction Most common cause is choledocholithiasis Most common organisms present in the bile in patients with cholangitis : E.coli (MC). Klebsiella pneumoniae, streptococcus faecalis & Bacteroides fragilis Ref: Sabiston 20th edition Pgno :1507", "cop": 1, "opa": "E.coli", "opb": "Streptococcus", "opc": "E.histolytica", "opd": "Clostridium", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "33f5a0ca-4e56-4e1a-9b56-5baec191e23f", "choice_type": "single"} {"question": "Nerve root of pudendal nerve is", "exp": "The pudendal nerve is derived from the sacral roots of S2-S4 and later divides into three branches, the dorsal clitoral/penile, the perineal, and the rectal. It carries motor, sensory and autonomic fibers. Ref - BDC 6e vol2 pg363", "cop": 2, "opa": "S1 S2 S3", "opb": "S2 S3 S4", "opc": "S3 - S4", "opd": "S2 - S3", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "277dcba2-b702-49ff-b8be-2caa2a98c34d", "choice_type": "single"} {"question": "Pott's puffy tumor is", "exp": "POTT'S PUFFY TUMOUR It is formation of diffuse external swelling in the scalp due to subperiosteal pus formation (abscess) and scalp oedema. x It originates commonly in frontal region and may extend into other regions. x There is acute osteomyelitis of frontal bone. Causes x Chronic frontal sinusitis which eventually suppurates and extends into subperiosteal region. x Trauma--subperiosteal haematoma. x Chronic suppurative otitis media. Features x Pain and boggy swelling in frontal region which is warm, tender. x Toxicity and drowsiness. x Pitting scalp oedema is typical. x Investigations: \u0017 Total leucocyte count--increased. ESR--raised. \u0017 X-ray skull. CT scan. x Differential diagnosis: Secondaries in the skull or brain. Complications Osteomyelitis of frontal bone. Spread of infection into intracranial cavity leads to intracranial abscess (Extradural or subdural abscess) (dumb-bell abscess). So may present with features of raised intracranial tension like headache, coning and convulsions. Pott's Puffy tumor can be associated with coical vein throm- bosis, epidural brain abscess/subdural empyema. The cause of vein thrombosis is explained by diplopic veins in frontal bone, which communicates with the dural venous plexus; septic thrombi can potentially evolve from foci within the frontal sinus and propagate through this venous system. Treatment x Antibiotics and drainage under general anaesthesia before it spreads into cranial cavity. x Once it extends into cranial cavity, it is treated accordingly by formal neurosurgical decompression (often using Dandy's brain cannula). x Osteomyelitis of skull bones requires radical removal with recon- struction of skull defect. Ref: SRB manual of surgery 5th edition Pgno: 48", "cop": 1, "opa": "Sub periosteal abscess of frontal bone", "opb": "Sub periosteal abscess of ethmoid bone", "opc": "Mucocele of frontal bone", "opd": "Mucocele of ethmoid bone", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "99b5791c-daca-4f0d-9389-417735a20353", "choice_type": "single"} {"question": "3rd extensor compament of wrist contains tendon of", "exp": "-The extensor retinaculum is a thickened band of deep fascia on the back of wrist. the anterior or deep aspect of this retinaculum is divided into 6osseofibrous compaments by 5 septa arising from back of radius and ulna. These tunnels provide passage to the extensor tendons.they are numbered 1 to 6 lateral to medially. the third compament provides passage to EPL tendon.Reference: clinical anatomy for students a problem-solving approach, Neeta v Kulkarni, page no.84", "cop": 3, "opa": "Extensor carpi radialis longus", "opb": "Extensor carpi radialis brevis", "opc": "Extensor pollicis longus", "opd": "Extensor pollicis brevis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "47a044e6-1cfa-4bf0-add4-cc5b1af1e9e7", "choice_type": "single"} {"question": "Nasolacrimal duct opens into the", "exp": "Nasolacrimal duct is membranous passage 18 mm long.it begins at the lower end of lacrimal sac, runs downwards, backward and laterally, and opens into the inferior meatus of the nose.A fold of mucous membrane called the valve of Hasner forms an imperfect valve at the lower end of the duct. Ref.BDC volume 3;sixth edition pg.76", "cop": 4, "opa": "Supreme meatus", "opb": "Superior meatus", "opc": "Middle meatus", "opd": "Inferior meatus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "c80edfeb-0fd7-4d41-b6e9-47eedf3e1cfa", "choice_type": "single"} {"question": "Most common cause of mitral stenosis is", "exp": "Refer robbins 9/e 554 Rheumatic hea disease (RHD) is damage to one or more hea valves that remains after an episode of acute rheumatic fever (ARF) is resolved. It is caused by an episode or recurrent episodes of ARF, where the hea has become inflamed. The hea valves can remain stretched and/or scarred, and normal blood flow through damaged valves is interrupted. Blood may flow backward through stretched valves that do not close properly, or may be blocked due to scarred valves not opening properly. When the hea is damaged in this way, the hea valves are unable to function adequately, and hea surgery may be required. Untreated, RHD causes hea failure and those affected are at risk of arrhythmias, stroke, endocarditis and complications of pregnancy. These conditions cause progressive disability, reduce quality of life and can cause premature death in young adults. Hea surgery can manage some of these problems and prolong life but does not cure RHD.", "cop": 1, "opa": "Rheumatic hea disease", "opb": "Infective endocarditis", "opc": "Diabetes mellitus", "opd": "Congenital", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "e5fda1f8-c7f7-4b5b-869d-a58a24a5b1e9", "choice_type": "single"} {"question": "Choose the most effective drug for mild intestinal amoebiasis and asymptomatic cyst passers", "exp": "Ref-KDT 6/e p801 Diloxanide is a medication used to treat amoeba infections. In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. It is taken by mouth.", "cop": 4, "opa": "Metronidazole", "opb": "Emetine", "opc": "Quiniodochlor", "opd": "Diloxanide furoate", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "a51274df-04a6-4eb0-bb19-c1701e8c4640", "choice_type": "single"} {"question": "Propranolol a non selective Beta blocker can be prescribed to decrease anxiety associated with", "exp": "Ref-KDT 6/e p143 Propranolol is used for controlling the performance anxiety, major manifestation of which are due to increase the sympathetic activity (tachycardia, palpilpalpit etc)", "cop": 3, "opa": "Chronic neurotic disorder", "opb": "Schizophrenia", "opc": "Sho term stressful situation", "opd": "Endogenous depression", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "1795a9e0-2cd0-477c-9cdb-754a3d057a73", "choice_type": "single"} {"question": "Special stain useful in the following condition", "exp": ".", "cop": 4, "opa": "Alcian blue", "opb": "Perls Prussian blue", "opc": "Masson Fontana", "opd": "Von kossa", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "79744221-e50d-4ef0-9c6f-879df37bc853", "choice_type": "single"} {"question": "neologism is a charecterstic of", "exp": "Type of thought disorder clinical condition clang assosiation mania flight of ideas mania prolixity hypomania loosening of assosiation schizophrenia neologism schizophrenia circumstantiality organicity Ref. Kaplon and Sadock, synopsis of psychiatry, 11 th edition, Pg.No.194", "cop": 1, "opa": "schizophrenia", "opb": "mania", "opc": "depression", "opd": "phobia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f0ce898a-eeaa-4288-a7c0-ca7cd1940256", "choice_type": "single"} {"question": "A patient woke up from sleep with difficulty in extending fingers. He can make a grip and hold apen. Wrist extension was possible. No sensory disturbance was found. Injury could be at", "exp": "Posterior interosseous nerve emerges from supinator on the back of the forearm .and lies between the superficial and deep muscles.At the lower border of the extensor pollicis brevis, it passes deep to the extensor pollicis longus .it then runs on the posterior surface of the interosseous membrane up to the wrist where it enlarges into pseudoganglion and ends by supplying the wrist and intercarpal joints. Reference : page no: 136 - BD chaurasia,upper limb & thorax", "cop": 2, "opa": "C8,T1", "opb": "Posterior interosseous nerve", "opc": "Lower pa of brachial plexus", "opd": "Hand area in motor coex", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "b70245bd-530b-4549-b19f-70a3040f7cc4", "choice_type": "single"} {"question": "According to MTP Act, aboion can be done till", "exp": "The Medical Termination of Pregnancy (MTP) Act of IndiaIt clearly states the conditions under which a pregnancy can be ended or aboed the persons who are qualified to conduct the aboion and the place of implementation.Women whose physical and/or mental health were endangered by the pregnancy.Women facing the bih of a potentially handicapped or malformed child.Rape.Pregnancies in unmarried girls under the age of eighteen with the consent of a guardianPregnancies in \"lunatics\" with the consent of a guardianPregnancies that result are a result of failure in sterilization.The length of the pregnancy must not exceed 20 weeks in order to qualify for an aboionMTP Act of 1971 legalizes aboion on the following grounds;TherapeuticEugenic.HumanitarianSocial.MTP RULESOnly registered medical practitioner can perform MTP;Should only be done in Government hospitals or hospitals recognized by GovernmentConsent of woman is required.If minor or mentally ill, written consent from guardian is required.If period of pregnancy is less than 12 weeks, opinion of single doctor is enough.If period of pregnancy is between 12-20 weeks, opinion of 2 doctors required.Refer: Rajesh Bardale - Principle of Forensic Medicine & Toxicology, 1st edition, pg no: 351,352", "cop": 2, "opa": "12 weeks", "opb": "20 weeks", "opc": "28 weeks", "opd": "Till bility", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d8875d1f-c025-43cf-b465-1ddef81b77f9", "choice_type": "single"} {"question": "graded exposure to phobic stimulus along with relaxation is given by", "exp": "SYSTEMATIC DESENSITIZATION JOSEPH WOLPE Joseph Wolpe gave the concept of systematic desensitization This is a treatment used in phobia In phobia there is a conditioned fear response to aversive neutral stimulus and avoidance of that response leads to phobia Whenever there is a fear response there is stimulation of sympathetic system In that case stimulation of parasympathetic system by relaxation there is reduction in anxiety First step is to make a step ladder which are arranged based on the severity Then is go step by step and along with doing applied relaxation Slowly the the sympathetic system is reduced The patient will be able to approach stimulus without anxiety Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 4, "opa": "bleuler", "opb": "skinner", "opc": "freud", "opd": "wolpe", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "b0d8ea26-8154-40f5-aae6-d171b489c0d2", "choice_type": "single"} {"question": "The hyaloid canal is found in the", "exp": "The hyaloid canal (Cloquet's canal) is found in the vitreous body. In early development, a hyaloid aery passes through the vitreous body to perfuse the developing lens; in the late fetal period, this aery is obliterated to form the hyaloid canal.", "cop": 1, "opa": "Vitreous body", "opb": "Choroid", "opc": "Optic stalk", "opd": "Ciliary body", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "d8d160df-8824-4202-b2f8-5c3435eb1c83", "choice_type": "single"} {"question": "Muscles of facial expression develops from", "exp": null, "cop": 2, "opa": "I Arch", "opb": "II Arch", "opc": "III Arch", "opd": "IV Arch", "subject_name": "Anatomy", "topic_name": null, "id": "47f605a6-1cd4-4828-8c71-3d4d3ba00ec6", "choice_type": "single"} {"question": "Spinal pa of accessory nerve supplies", "exp": "Sternocleidomastoid and trapezius are supplied by spinal accessory nerve. Both of them develop from brachial arch mesoderm.It is tested by turning the neck against resistance.B D Chaurasia 7th edition Page no: 65 ( refer head and neck volume )", "cop": 2, "opa": "Platysma", "opb": "Sternocleidomastoid", "opc": "Stylohyoid", "opd": "Diagastric", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "b3d16fe0-c691-466d-a136-9d5c13c4b385", "choice_type": "single"} {"question": "These ventral spinal rootlets are more prone to injury during decompressive operations because they are shorter and exit in a more horizontal direction", "exp": "Due to rostral shift of the spinal cord during development, the spinal nerve roots become progressively oblique from above downwards.\nIn upper cervical region, the spinal nerve roots are short and run almost horizontally but the roots of the lumbar and sacral nerves are long and run almost vertically.", "cop": 1, "opa": "C5", "opb": "C6", "opc": "C7", "opd": "T1", "subject_name": "Anatomy", "topic_name": null, "id": "51258ad3-2667-4621-a7c3-a4ddae3d8de5", "choice_type": "single"} {"question": "First web space of toes is supplied by", "exp": "Deep peroneal nerve is the nerve of anterior compament of the leg and the dorsum of foot. This is one of the two terminal branches of common peroneal nerve ( ventral primary rami of L4, L5, S1 and S2 segment) The nerve ends on the dorsum of the foot, close to the ankle joint, by dividing into lateral and medial terminal branches. Lateral terminal branch turns laterally and ends in pseudo ganglion deep to the extended digitorum brevis. Medial terminal branch ends by supplying skin adjoining the first interdigital cleft and the proximal joints of the big toe. Femoral nerve is the nerve of anterior compament of thigh. Root value - dorsal division of ant primary rami of L2 L3 L4 ). Superficial peroneal nerve is smaller terminal branch of common paroneal nerve.Its branches supply the skin over lower 1/3 of lateral side of the leg, skin over the entire dorsum of foot except lateral border supplied by dural nerve and medial border up to base of great toe supplied by saphenous nerve and cleft between 1st and 2nd toes supplied by deep peroneal nerve Ref: BD Chaurasia(6th edition pg-95,96)", "cop": 2, "opa": "Femoral nerve", "opb": "Deep peroneal nerve", "opc": "Superficial paroneal nerve", "opd": "Saphenous nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "89ee80b2-862e-487c-af56-9f1580b827d6", "choice_type": "single"} {"question": "A 14 year old boy present with headache fever and cough for 2 days. Sputum is scant and non purulent and gram stain reveals many white cells but no organisms. The treatment should be initiated with", "exp": "Ref-KDT 6/e p729 Diagnosis is atypical pneumonia in the DOC is Erythromycin.", "cop": 2, "opa": "Cefazolin", "opb": "Erythromycin", "opc": "Amikacin", "opd": "Trovafloxacin", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "3f8df8a1-2624-4149-996f-8b25e655a6b6", "choice_type": "single"} {"question": "Ligament suppoing the talus is", "exp": "SPRING LIGAMENT:- Also known as plantar calcaneonavicular ligament.Attachments-Anteriorly:plantar surface of navicular bone.Posteriorly: anterior margin of sustentaculum tali. Head of talus directly rests on upper surface of the ligament. The plantar surface of the ligament is suppoed by tendon of tibialis posterior medially,and by tendons of flexor hallucis longus and flexor digitorum longus laterally.Most impoant ligament for maintaining the medial longitudinal arch of foot. {Reference: BDC 6E}", "cop": 1, "opa": "Spring ligament", "opb": "Deltoid ligament", "opc": "Calcaneocuboid ligament", "opd": "Cervical ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "72503d47-1485-471c-b447-f4fbb89db563", "choice_type": "single"} {"question": "Embryonic period of development is", "exp": "Development before bih is called prenatal development, and that after bih is called postnatal development. There are three stages in prenatal development. They are: 1. Preimplantation/pre-embryonic period 2. Embryonic period 3. Fetal period. Embryonic Period- It extends from 3rd week of intrauterine life to 8th week of intrauterine life. The following morphogenetic events take place during this period : 1. Trilaminar germ disc differentiation: Formation of three layered germ disc with the appearance of mesoderm in between ectoderm and endoderm. 2. Early organogenesis: Formation of primordia of various organs like lungs, hea, liver, etc. 3. Formation of extraembryonic suppoive organs and membranes: Placenta, umbilical cord, amnion, allantois. Ref:Inderbir Singh's Human Embryology, eleventh edition , pg. no.,2.", "cop": 4, "opa": "Up to 16 weeks", "opb": "Up to 12 weeks", "opc": "Up to 10 weeks", "opd": "Up to 8 weeks", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a252b919-f8f3-456f-afb1-233fec4a09a2", "choice_type": "single"} {"question": "Barrett oesophagus can result from", "exp": "Refer Robbins page no p 957 Barrett esophagus is a complication of chronic GERD that is characterized by intestinal metaplasia within the esophageal squamous mucosa. The incidence of Barrett esophagus is rising, and it is estimated to occur in as many as 10% of individuals with symptomatic GERD. Barrett esophagus is most common in white males and typically presents between 40 and 60 years of age. The greatest concern in Barrett esophagus is that it confers an increased risk of esoph- ageal adenocarcinoma. Genomic sequencing of biopsies involved by Barrett esophagus has revealed the presence of mutations that are shared with esophageal adenocarci- noma, in keeping with the idea that Barrett esophagus is a precursor lesion to cancer. Potentially oncogenic mutations are more numerous when biopsies demonstrate dysplasia, which is detected in 0.2% to 2% of persons with Barrett esophagus each year. The presence of dysplasia, a prein- vasive change, is associated with prolonged symptoms, longer segment length, increased patient age, and Caucasian race. Although the vast majority of esophageal adenocar- cinomas are associated with Barrett esophagus, it is impor- tant to remember that most individuals with Barrett esophagus do not develop esophageal tumors.", "cop": 3, "opa": "H. Pylori infection", "opb": "H. Simplex infection", "opc": "Gastroesophagal reflux", "opd": "Varices", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0931470a-7364-48d8-ac12-864cab2f0066", "choice_type": "single"} {"question": "A patient on total parenteral nutrition for 20 days presents with weakness, veigo and convulsions. Diagnosis is", "exp": "Clinical features for complications of Parenteral Nutrition Hypomagnesemia Weakness, muscle cramps and tremors Marked neuromuscular and CNS hyperirritability with jerking and nystagmus Hyperkalemia Interferes with neuromuscular function to produce muscle weakness which may progress to flaccid paralysis and hypoventilation if respiratory muscles are involved Hypercalcemia Fatigue, depression,mental confusion, lethargy Anorexia, nausea, vomiting, constipation and polyuria Ref: Harrison's 19th edition Pgno :88-97", "cop": 2, "opa": "Hypermagnesemia", "opb": "Hypomagnesemia", "opc": "Hypercalcemia", "opd": "Hypocalcemia", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "f9ef78ff-387c-440c-acb0-35554c2681dc", "choice_type": "single"} {"question": "The screening for HCC in chronic liver disease", "exp": "Screening is based on regular ultra sound scanning in high risk population and measurement of AFP levels Ref:Sabiston 20th edition Pgno : 1458-1463", "cop": 1, "opa": "Serial USG + AFP", "opb": "Serial LFT+AFP", "opc": "Serial LFT+CT scan", "opd": "Serial USG + serial LFT", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8a178b56-78f3-4683-86da-5def00206bbf", "choice_type": "single"} {"question": "Not a B cell marker", "exp": ".", "cop": 3, "opa": "CD19", "opb": "CD20", "opc": "CD34", "opd": "CD10", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "27707cf2-995b-424d-8125-830584dad760", "choice_type": "single"} {"question": "Adductor tubercle gives attachement to", "exp": "ADDUCTOR TUBERCLE:- Posterosuperior to medial epicondyl there is a projection called adductor tubercle. It gives attachment to the inseion of hamstring or ischial head of adductor Magnus. Adductor brevis inseed into the line extending from lesser trochanter to upper pa of linea aspera. Adductor longus inseed into the medial lip of linea aspera between vastus medialis and adductor brevis and magnus. Vastus intermedialis- arise from femur shaft ( upper three fouh of anterior and lateral surface) {Reference: BDC 6E pg no.17}", "cop": 1, "opa": "Adductor magnus", "opb": "Adductor brevis", "opc": "Adductor longus", "opd": "Vastus intermedius", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "aadc3664-0059-423a-a0ad-3387ea6eb607", "choice_type": "single"} {"question": "neuroleptic malignant syndrome is treated with", "exp": "neuroleptic malignant syndrome is a type of movement disorder assosiated with CLINICAL CRITERIA * 106:F * Abrupt onset * Any of the two * Diaphoresis * Tachycardia Labile bp ETIOLOGY Introduction of Dopamine antagonists or Abrupt Discontinuation Of an antipsychotic this can be treated with Dantrolene sodium and syndopa Ref.kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no. 925", "cop": 1, "opa": "dantrolene sodium", "opb": "propanolol", "opc": "pacitine", "opd": "clonazepam", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "40fd63d9-39cb-4015-823c-cf78f3a8e849", "choice_type": "single"} {"question": "Puschers retinopathy is seen unn", "exp": "Refer Robbins Puschers retinopathy is manifestrd by a sudden death and severe loss of vision In a patient with acute pancreatitis. It is caused by occlusion of the posterior retinal aery with aggregated granulocytes. There to cotton wool spots and haemorrhage confined to an area. Limited NY the optic disc and macula", "cop": 2, "opa": "Meningitis", "opb": "Pancreatitis", "opc": "Uncontrolled hypeension", "opd": "Unilateral carotid aery occlusion", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "aa9542a2-5d56-4f8d-ac2a-0e96acbac48d", "choice_type": "single"} {"question": "Mycotic abcesses are due to", "exp": "As the name suggests , mycotic abcesses are caused by fungal infections . However mucous aneurysm is caused due to bacterial infection of aerial wall . The infection weakens the wall and causes aneurysm .", "cop": 3, "opa": "Bacterial Infection", "opb": "Viral infection", "opc": "Fungal infection", "opd": "Mixed infection", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0c62d424-14ad-454c-bb66-f58dee48a5da", "choice_type": "single"} {"question": "drug used in the management of treatment resistant schizophrenia is", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients Ref.kaplon and sadock, synopsis of psychiatry, 11 th dition, 935", "cop": 1, "opa": "clozapine", "opb": "olanzapine", "opc": "flupenthixol", "opd": "haloperissol", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "3725fc49-94c1-498b-8836-43d2d3934255", "choice_type": "single"} {"question": "Facial colliculus is seen in", "exp": "The motor fibres of the facial nerve undergo a loop course around the dorsomedial aspect of abducent nerve nucleus, producing the facial colliculus in the pons. In the early embryogenesis, the motor nucleus of facial nerve is located dorsolateral to cranial end of abducent nucleus. Gradually, it migrates in close proximity to the Spinal nucleus of trigeminal nerve which is called \"NEUROBIOTAXIS\". (Ref: Vishram Singh textbook of clinical neuroanatomy, second edition pg 80)", "cop": 2, "opa": "Midbrain", "opb": "Pons", "opc": "Medulla", "opd": "Interpeduncular foosa", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "83b50e65-7b7d-4030-86b1-3e480f05280c", "choice_type": "single"} {"question": "Gluteofemoral bursa is in between gluteus maximus and", "exp": "Bursae between gluteal maximus and vastus lateralis is called Gluteofemoral bursa. Between gluteus maximus and trochanter is trochanteric bursa. There is also a bursa over ischial tuberosity. {Reference: BDC 6E pgno. 70}", "cop": 4, "opa": "Greater trochanter", "opb": "Lesser trochanter", "opc": "Ischeal tuberosity", "opd": "Vastus lateralis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "de37bc2e-03f7-4491-8b8f-3b77ac42c919", "choice_type": "single"} {"question": "Mechanism of action of paralidoxime is", "exp": "Pralidoxime and diacetylmonoxime are cholinesterase regenerator compound used for organophosphate poisoning. Ref-KDT 6/e p105", "cop": 4, "opa": "Stimulation of ACh receptors", "opb": "Inhabitation of breakdown of ACh", "opc": "Blockade of ACh receptors", "opd": "Deactivation of ACh enzyme", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "98adc1a6-eb98-4dda-bbc4-d17992952361", "choice_type": "single"} {"question": "Superior and inferior vesicular aery is a branch of", "exp": "The superior and inferior vesical aery is a branch(direct or indirect) of the anterior division of the internal iliac aery. It frequently arises in common with the middle rectal aery, and is distributed to the fundus of the bladder. In males, it also supplies the prostate and the seminal vesicles. ref - researchgate.net", "cop": 3, "opa": "Abdominal aoa", "opb": "Obturator aery", "opc": "Internal iliac aery", "opd": "External iliac aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "96f71f2a-430c-446f-8a07-8660f3f492a2", "choice_type": "single"} {"question": "Tissue thromboplastin activates", "exp": "Ref Robbins 9/e, p 118 Coagulation Cascade The coagulation cascade constitutes the third arm of the hemostatic system. The pathways are schematically pre- sented in Figure 3-8; only general principles are discussed here. The coagulation cascade is a successive series of ampli- fying enzymatic reactions. At each step in the process, a proenzyme is proteolyzed to become an active enzyme, which in turn proteolyzes the next proenzyme in the series, eventually leading to the activation of thrombin and the formation of fibrin. Thrombin has a key role, as it acts at numerous points in the cascade (highlighted in Fig. 3-8). Thrombin proteolyzes fibrinogen into fibrin monomers that polymerize into an insoluble gel; this gel encases platelets and other circulating cells in the definitive secondary hemostatic plug. Fibrin polymers are stabilized by the cross-linking activity of factor XIIIa, which also is activated by thrombin. Each reaction in the pathway depends on the assembly of a complex composed of an enzyme (an activated coagula- tion factor), a substrate (a proenzyme form of the next coag- ulation factor in the series), and a cofactor (a reaction accelerator). These components typically are assembled on a phospholipid surface (provided by endothelial cells or platelets) and are held together by interactions that depend on calcium ions (explaining why blood clotting is preventedby calcium chelators). Figure 3-8 The coagulation cascade. Factor IX can be activated by either factor XIa or factor VIIa: In laboratory tests, activation is predominantly dependent on factor XIa, whereas in vivo, factor VIIa appears to be the predominant activator of factor IX. Factors in red boxes represent inactive molecules; activated factors, indicated with a lowercase a, are in green boxes. Note that thrombin (factor IIa) (in light blue boxes) contributes to coagula- tion through multiple positive feedback loops. The red X's denote points at which tissue factor pathway inhibitor (TFPI) inhibits activation of factor X and factor IX by factor VIIa. HMWK, high-molecular-weight kininogen; PL, phospholipid.", "cop": 1, "opa": "Factor 7", "opb": "Factor 4", "opc": "Factor 6", "opd": "Factor12", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ee7f28c6-6a10-4bc9-894f-5d8c708589d9", "choice_type": "single"} {"question": "Winging of scapula is due to paralysis of", "exp": "WINGING OF SCAPULA: Paralysis of serratus anterior causes 'winging of scapula' It is supplied by the long thoracic nerve. FEATURES: Medial border of the scapula becomes unduly prominent The inferior angle becomes prominent. The arm cannot be abducted beyond 90degree. REF: BD Chaurasia 7th edition page no: 12.", "cop": 2, "opa": "Pectoralis major", "opb": "Serratus anterior", "opc": "Pectoralis minor", "opd": "Latissimus dorsi", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "1fb61aec-64f0-4b97-90a2-00367e8cfe96", "choice_type": "single"} {"question": "Lining epithelium of ventricles of brain", "exp": "The cavity of ventricles is lined by ciliated columnar epithelium- the ependymal cells.Ependyma is one of the four types of neuroglia in the central nervous system.They are of three types: ependymocytes, choroid epithelial cells, tanycytes.TANYCYTES are the ependymal cells lining the floor of fouh ventricle having long basal process.It is involved in the production of cerebrospinal fluid(choroidal epithelial cells) and is shown to serve as a reservoir for neuroregeneration.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 15)", "cop": 2, "opa": "Squamous", "opb": "Columnar", "opc": "Cuboidal", "opd": "Transitional", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "a32e6448-c6d9-422b-9a28-704bf96470ac", "choice_type": "single"} {"question": "Malignant hydatidosis is caused by", "exp": ".", "cop": 2, "opa": "Echinococcus granulosus", "opb": "Echinococcus multilocularis", "opc": "Echinococcus vogelli", "opd": "Echinococcus oligahus", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0c8f98b2-8f99-421d-91e2-66d502d69a70", "choice_type": "single"} {"question": "POSTERIOR COMMUNICATING aery is a branch of", "exp": "Posterior communicating aery is a branch of cerebral pa of internal carotid aery. It arises close to its termination. It runs backwards and anastomoses with proximal pa of posterior cerebral aery.Reference: Textbook of anatomy, Head neck, and brain, Vishram Singh, 2nd edition, page no.406", "cop": 2, "opa": "Veebral aery", "opb": "Internal carotid aery", "opc": "External carotid aery", "opd": "Basillary aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "04e83658-0c35-4aad-84e7-eff80624a2f8", "choice_type": "single"} {"question": "Left trisegmentectomy involves removal of", "exp": "Trisegmentectomy Right trisegmentectomy or extended right hepatectomy : Complete resection of segment IV with the right liver (Removal of segment IV, V, VI, VII, VIII Left trisegmentectomy or extended left hepatectomy : Complete resection of segment V and VIII with left liver (removal of segment II, III, IV, V, VIII) Ref: Blumga 5th edition Pg no : 1512-1513", "cop": 1, "opa": "Segment II, III, IV, V, VIII", "opb": "Segment II, III, IV", "opc": "Segment IV, V, VI, VII, VIII", "opd": "Segment V, VI, VII, VIII", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5077c176-72ce-4c8e-ad31-2ed9965d4ab1", "choice_type": "single"} {"question": "Spleen projects into the following space of peritoneal cavity", "exp": "The diaphragmatic surface of the spleen (or phrenic surface) is convex, smooth, and is directed upward, backward, and to the left, except at its upper end, where it is directed slightly to the middle. It is in relation with the under surface of the diaphragm, which separates it from the ninth, tenth, and eleventh ribs of the left side, and the intervening lower border of the left lung and pleura. The visceral surface of the spleen is divided by a ridge into two regions: an anterior or gastric and a posterior or renal. The gastric surface (facies gastrica) is directed forward, upward, and toward the middle, is broad and concave, and is in contact with the posterior wall of the stomach. Ref - BDC vol2 6e pg295-298", "cop": 4, "opa": "Paracolic gutter", "opb": "Infracolic compament", "opc": "Left subhepatic space", "opd": "Greater Sac", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9a0f72a5-a20f-4ef8-a6f3-0ee9c3f1b3a1", "choice_type": "single"} {"question": "Hypoglossal nucleus lies on", "exp": "Hypoglossal nucleus is an elongated column of grey matter extending throughout the length of medulla oblongata in the paramedian plane. Note: *Midbrain - nuclei of 3,4 cranial nerves *Pons - nuclei of 5,6,7,8 cranial nerves * Medulla- nuclei of 9,10,11,12 cranial nerves (Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg -91, 92)", "cop": 3, "opa": "Mid brain", "opb": "Pons", "opc": "Medulla", "opd": "Lower pons", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "bd454538-4172-4c27-935e-d04e7bea7fdf", "choice_type": "single"} {"question": "Ritgen maneuver is done in", "exp": "Ritgen manuever is done for delivery of head in normal labor to allow controlled delivery of head. When the head distends the vulva and perineum enough to open the vaginal introitus to a diameter of 5cn of more , a towel is drapled ,gloved hand may be used to exe forward pressure on the chin of fetus through the perineum just in front of coccyx. Concurrently the other hand exes pressure superiorly against occiput. This ours nect extension so that the head is delivered with its smallest diameter passing through the introitus and over perineum", "cop": 4, "opa": "Shoulder dystocia", "opb": "For delivery of head in breech presentation", "opc": "For delivery of legs in breech", "opd": "For delivery of head in normal labour", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "3a35e70b-7ce6-42b1-85ab-25ee1be89659", "choice_type": "single"} {"question": "Nissl's (substance) bodies are seen in", "exp": "(A) Cell body # Nissl body (or Nissl granule or Tigroid body) is a large granular body found in nerve cells. It was named after Franz Nissl, German neurologist (1860-1919).> Nissl bodies can be demonstrated by selective staining, which was developed by Nissl and was an aniline stain used to label extranuclear RNA granules.> These granules are rough endoplasmic reticulum (with ribosomes) and are the site of protein synthesis.> Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (karyolysis).", "cop": 1, "opa": "Cell body", "opb": "Axon", "opc": "Dendrites", "opd": "Sheath", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "b9c0ba2e-e4fe-4054-a62e-16966041e8b4", "choice_type": "single"} {"question": "Round ligament of uterus is derived from", "exp": "The round ligament develops from the gubernaculum which attaches the gonad to the labioscrotal swelling in the embryo. The round ligament enters the pelvis the deep inguinal ring, passes through the inguinal canal and continues on to the labia majora where its fibers spread and mix with the tissue of the mons pubis.", "cop": 3, "opa": "Gonadal ridge", "opb": "Mullerian duct", "opc": "Gubernaculum", "opd": "Genital tubercle", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "77c71380-ff13-4ce2-bd55-d71c6c6b6e2b", "choice_type": "single"} {"question": "The term infantile polyaeritis nodosa was formerly used for", "exp": "Refer Robbins page no 510 Clinically infantile polyaeritis nodosa often ilia pa of the spectrum of Kawasaki disease", "cop": 3, "opa": "Goodpasteurs syndrome", "opb": "Henoch schenon purpura", "opc": "Kawasaki disease", "opd": "Takaysaus aeritis", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "061e522e-91bd-4595-9e89-f3ef3815c71f", "choice_type": "single"} {"question": "Ligamentum teres is the remnant of", "exp": "(A) Umbilical vein SOME FREQUENTLY ASKED REMNANTS* Ductus arteriosusLigamentum arteriosum* Ductus venosusLigamentum venosum* Left umbilical veinLigamentum teres of liver* Right umbilical veinDisappears* Vitello-intestinal ductMeckel's diverticulum* Wolffian ductGartner duct> After obliteration, the umbilical vein forms the ligamentum teres and the ductus venosus becomes ligamentum venosum.", "cop": 1, "opa": "Umbilical vein", "opb": "Portal vein", "opc": "Ductus venosus", "opd": "Umbilical artery", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "a677f0a3-b6b2-42d3-908b-0c1d30c5e1ae", "choice_type": "single"} {"question": "Insertion of extensor carpi ulnaris", "exp": "Ans. is 'c' i.e., Base of 5th MetacarpalExtensor carpi ulnariso Origin : Lateral epicondyle of humerus and posterior border ulnao Insertion : Base of 5th metacarpalo Nerve supply : Posterior interosseus nerveo Action : Extension (dorsiflexion) and adduction of hand.", "cop": 3, "opa": "Base of proximal phalanx of thumb", "opb": "Base of Distal phalanx of thumb", "opc": "Base of 5th Metacarpal", "opd": "Scaphoid base", "subject_name": "Anatomy", "topic_name": "Hand", "id": "d3a126b6-18fd-4846-a6a1-892929580360", "choice_type": "single"} {"question": "Corneal epithelium consist of", "exp": "(B) (Stratified, squamous non keratinized) (390-92-I-B. Singh 7th)Key points of cornea (colour less and avascular but has a very rich nerve supply)1. Stratified squamous, non keratinized corneal epithelium -outermost layer2. Anterior limiting membrane (Bowman's membranes)3. Substantia propri- made up of collagen fibres4. Posterior limiting membrane (Descemet's membrane)5. Posterior cuboidal epithelium* Afferent of corneal reflex-trigeminal nerve. (Ophthalmic branch)* Efferent of corneal reflex-facial nerveDEVELOPMENTMesodermExtra- ocular muscle, comeal stroma. Sclera , iris, vascular endothelium of eye, and orbit, choroid parts of vitreousNeural ectodermSmooth muscle of the iris (Dilator sphineter), optic vesicle and cup, iris epithelium, ciliary epithelium, parts of vitreous, Retina, Retinal pigment epitheliumSurface ectodermConjunctival epithelium, comeal epithelium, Lacrimal glands. Tarsal glands. Lens", "cop": 2, "opa": "Stratified squamous keratinized", "opb": "Stratifed squamous non keratinized", "opc": "Columnar epithelium", "opd": "Pseudo stratified epithelium", "subject_name": "Anatomy", "topic_name": "Histology", "id": "d7101866-c15d-4ffc-a076-0ef1d73161eb", "choice_type": "single"} {"question": "Deep brain stimulation has been approved for treatment of", "exp": "DBS is approved only for treatment resistant parkinsonism by FDA, Has been tried for treatment resistant depression, OCD, other movement disorders", "cop": 1, "opa": "Movement disorders like Parkinsonism", "opb": "Schizophrenia", "opc": "Depression", "opd": "Anxiety disorder", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "5782db5c-0b54-482a-b5e8-bcbdc9b288d1", "choice_type": "single"} {"question": "Most common site for intra abdominal abscess following laparotomy is", "exp": "RIGHT SUBHEPATIC SPACE This lies transversely beneath the right lobe of the liver in Rutherford Morison's pouch. It is bounded on the right by the right lobe of the liver and the diaphragm. To the left is situated the foramen of Winslow and below this lies the duodenum. In front are the liver and the gall bladder, and behind are the upper pa of the right kidney and the diaphragm. The space is bounded above by the liver and below by the transverse colon and hepatic flexure. It is the deepest space of the four and the most common site of a subphrenic abscess, which usually arises from appendicitis, cholecystitis, a perforated duodenal ulcer or following upper abdominal surgery It is the most dependent poion of the abdominal cavity in the recumbent position Ref: Bailey and love 27th edition Pgno : 1056", "cop": 1, "opa": "Sub hepatic", "opb": "Subphrenic", "opc": "Pelvic", "opd": "Paracolic", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8e90eeb0-2ded-4a87-b235-246e28b5dc70", "choice_type": "single"} {"question": "Mastoid fontanelle closes by", "exp": "Closure of Fontanelles:1. Anterior fontanelle by 18 months2. Posterior fontanelle by 2-3 months3. Sphenoidal fontanelle by 2-3 months and 4. Mastoid fontanelle by 12 months Reference: Chourasia; 6th edition; 12th page", "cop": 3, "opa": "1-3 months", "opb": "3-6 months", "opc": "11-12 months", "opd": "18-24 months", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6b095218-339a-41f8-af86-76ab8c7b7a82", "choice_type": "single"} {"question": "IVC obstruction presents with", "exp": "IVC obstruction presents with Thoraco epigastric dilation Blockade of IVC causes a communication between SVC & IVC by azygos vein due to which blood from IVC enters the SVC. A communication also sets up b/w superior and inferior epigastric vein in the rectus sheath which drains into Brachiocephalic vein Internal thoracic vein. Superficial Epigastric vein forms collaterals with Lateral Thoracic vein thoracoepigastric vein in case of either IVC or SVC obstruction Normally blood flow in the veins of anterior abdominal wall is in upward direction above the plane of the umbilicus and in downward direction below the plane of umblicus. But in case of IVC obstruction it is completely in upward direction ( both above and below the plane)", "cop": 4, "opa": "Esophageal varices", "opb": "Haemorrhoids", "opc": "Para-umbilical dilatation", "opd": "Thoraco-epigastric dilatation", "subject_name": "Anatomy", "topic_name": "Thorax- wall and Bronchopulmonary segment", "id": "daf1c228-90fc-48dc-a53f-25492ef74851", "choice_type": "single"} {"question": "Lipid in the tissues is detected by", "exp": "Oil Red O Ref, Bancroft histology 6/e p53", "cop": 3, "opa": "PAS", "opb": "Myeloperoxidase", "opc": "Oil Red O", "opd": "Mucicarmine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fafb1f45-4905-4f65-9f28-8b7952443b4e", "choice_type": "single"} {"question": "Necrotizing lymphadenitis is seen in", "exp": "Ref Harrison 17/e p1011 The other name for kikuchis fujimoto disease is histocytic nercrotizing lymphadenitis. Benign and self-centered disorder in young individuals characterised by cervical lymphadenopathy With tenderness .usually accompanied with mild fever and night sweats,may b viral on ethilogy", "cop": 2, "opa": "Kimura disease", "opb": "Kikuchis fujimoto disease", "opc": "Hodgkin's lymphoma", "opd": "Castelman disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "116b3476-84b9-4c03-91a8-08aca521b965", "choice_type": "single"} {"question": "Muller&;s muscle is found in", "exp": "Mullers muscle or involuntary pa of levator palpebrae superioris is supplied by sympathetic fibres from the superior cervical ganglion. Paralysis of mullers muscle leads to paial ptosis. This is a pa of horners syndrome. Ref BDC volume 3,Sixth edition pg 74", "cop": 3, "opa": "Pharynx", "opb": "Middle ear", "opc": "Eye lid", "opd": "Tongue", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "7c46e144-166b-43d9-aedf-be51177f9ced", "choice_type": "single"} {"question": "SA Node is located at", "exp": "SA node is situated at the atriocaval junction in the upper pa of the sulcus terminalis B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME 1 SIXTH EDITION Page no-262", "cop": 1, "opa": "Upper end crista terminalis", "opb": "Lower end of crista terminalis", "opc": "At opening of IVC", "opd": "At ostium primum", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ce726946-4c40-447b-ab9f-064b43256c69", "choice_type": "single"} {"question": "Location of Testis in the 7th month of Gestation", "exp": "Descent of Testis:The testes develop in relation to the developing mesonephros, at the level of segments T10 to T12. Subsequently, they descend to reach the scrotum. Each testis begins to descend during the second month of intrauterine life. It reaches the iliac fossa by the 3rd month, rests at the deep inguinal ring from the 4th to the 6th month, traverses the inguinal canal during the 7th month, reaches the superficial inguinal ring by the 8th month and the bottom of the scrotum by the 9th month.Reference: Chaurasia Volume II; 7th edition; Page no: 249", "cop": 3, "opa": "Iliac Fossa", "opb": "Deep Inguinal Ring", "opc": "Inguinal canal", "opd": "Superficial Inguinal ring", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f8bf3b7a-1bef-44d3-9695-b5855c60f12b", "choice_type": "single"} {"question": "Collecting tubules of kidney develop from", "exp": "Collecting ducts of the permanent kidney develop from the ureteric bud, an outgrowth of the mesonephric duct close to its entrance to the cloaca. The bud penetrates the metanephric tissue, which is molded over its distal end as a cap. Subsequently, the bud dilates, forming the primitive renal pelvis, and splits into cranial and caudal poions, the future major calyces.Ref: Guyton; 13th edition; Chapter 65; Secretory Functions of the Alimentary Tract", "cop": 1, "opa": "Ureteric bud", "opb": "Mesonephric duct", "opc": "Paramesonephric duct", "opd": "Wolffian duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6a720dd4-4e5a-4595-b506-28e2c11452d6", "choice_type": "single"} {"question": "Most common primary leading to secondaries in pancreas", "exp": "Metastatic Tumors to pancreas MC site of primary : RCC > Malignant melanoma On autopsy, most common primary : CA Lung Ref: Sabiston 20th edition Pgno : 1544", "cop": 1, "opa": "Lung", "opb": "Breast", "opc": "Colon", "opd": "Stomach", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6e27de8a-38fd-47dc-9454-d1f53e80b0a0", "choice_type": "single"} {"question": "Majority of lung cysts occur in", "exp": "The bronchogenic cyst is a congenital lung lesion which arises from the anomalous development of foregut or tracheobronchial tree. Characteristics of Bronchogenic Cysts - Most of the Bronchogenic cysts arise in the mediastinum but ~15% occur in pulmonary parenchyma. In the mediastinum, they are usually located just posterior to the carnia or main stem bronchi. Mediastinal bronchogenic cysts do not communicate with the bronchi but those situated within the lung may communicate with the airways and consequently are prone to abscess formation. When located in the lung, they are more common in right lung and lower lobes These are lined by cuboidal or ciliated columnar epithelium and are usually filled with mucoid material. Complication: - Infection of the cyst leads to abscess Compression can produce either hyper infection of the lung or atelectasis due to obstruction Tension pneumothorax - d/t Rupture of the cyst that communicates with bronchus.", "cop": 1, "opa": "Mediastinum", "opb": "Near carina", "opc": "Base of the lung", "opd": "Peribronchial tissue", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "66f5931f-f40d-4582-8b50-a96d7ec2adab", "choice_type": "single"} {"question": "Synesthesia is seen with", "exp": ".", "cop": 2, "opa": "Cocaine", "opb": "LSD", "opc": "Opioids", "opd": "Methadone", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b85d3e77-42cd-4657-bf5f-741ef821cb5e", "choice_type": "single"} {"question": "Maximum growth spu in boys occurs at", "exp": "Height velocity curves for male, show maximum growth velocity at 14-15 yrs Height velocity curves for female,show maximum growth velocity at 11-13 yrs Ref: Nelson's 20th edition, page 84-89", "cop": 4, "opa": "8-10yrs", "opb": "10-12yrs", "opc": "12-13yrs", "opd": "14-15yrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f835566f-149c-4fb5-abab-b4a8e7611daf", "choice_type": "single"} {"question": "The procedure of choice for elective removal of CBD stones for most patients is", "exp": "Elective definitive treatment Cholecystectomy with choledochotomy and CBD exploration T-tube is left in place for cholangiography and removal of any retained stone T-tube cholangiogram is done on 7th - 10th day Post-operatively Remove the T-tube if cholangiogram is normal If residual stone is discovered on the postoperative cholangiogram, T-tube should be left in place for 4-6 weeks for the tract to mature The stones are removed percutaneously through the matured tract by Burhenne's technique Ref: Sabiston 20th edition Pgno : 1511", "cop": 1, "opa": "Open choledocholithotomy", "opb": "Laparoscopic choledocholithotomy", "opc": "Endoscopic choledocholithotomy", "opd": "Percutaneous choledocholithotomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8fc1322f-5d83-474d-a438-21046e2f5669", "choice_type": "single"} {"question": "Better prognostic factor for operation of biliary duct obstruction in newborn are", "exp": "Major factors in successful outcome after pooentreostomy Age in days at diagnosis and initial surgery (30-60 days) Length of time jaundice was present before surgery Successful and persistent bile flow postoperatively Size and nature of the microscopic ducts (>150um) Degree and extent of fibrotic changes in the liver Need for phototherapy as a neonate Technical aspects of the postenterostomy and anastomosis Presence of bile on hepatic lobular zone 1 Ref: Blumga 5th edition Pgno :600", "cop": 4, "opa": "No passage of bile", "opb": "Size of ductile >200 micron", "opc": "Weight of baby >3 kg", "opd": "Age of 8 weeks", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ffc7d1ea-4274-45c7-9240-b47bff8c6c4b", "choice_type": "single"} {"question": "Massive transfusion can cause a) Hyperkalemia b) DIC c) Thrombocytopenia d) Hypothermia", "exp": "Complications of Massive transfusion Massive transfusion cam lead to coagulapathy and metabolic complications Most common cause of death after massive transfusion : Dilutional Coagulopathy or DIC Transfusion of 15-20 units of blood components causes Dilutional thrombocytopenia After massive transfusion initially transient hyperglycemia due to glucose in preservatives leading to insulin release and causing hypoglycemia (MC) Galvimetric method of estimation of blood loss : Blood loss during operation is measured by weighing the swabs after use & subtracting the dry weight plus volume of blood collected in suction or drainage Metabolic complications of Massive transfusion General Fluid overload Hypothermia Impaired oxygen delivery capacity of Hb (decreased 2,3-DPG). Electrolyte Hyperkalemia Hypocalcemia Hypomagnesemia Metabolic alkalosis Metabolic acidosis (rare) Ref: Harrison's 19th edition Pgno :138", "cop": 4, "opa": "a,d", "opb": "b,c", "opc": "a,c,d", "opd": "a,b,c,d", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2a4d9231-b099-44c3-a814-20aa31b23592", "choice_type": "single"} {"question": "Pt. with chronic pancreatitis gives chain of lakes appearance in ERCP examination. MM is", "exp": "Areas of ductal dilatation alternating with areas of ductal stenosis are common finding in alcoholic patients who have severe chronic pancreatitis. This type of duct obstruction cannot be relieved by a sphincteroplasty because of multiple areas of stenosis along the duct. Although total pancreatectomy would be a beneficial approach, moality and morbidity rate with this procedure are extremely high. Thus the procedure of choice in this pt. is side to side pancreaticojejunostonzy in which the duct is opened longitudinally through the chain of lakes. A Roux-en-Y limb of jejunum should then be brought up for anastomosis with the opened pancreas in side-to-side fashion. Ref : Schwaz Pretest, 7/e, Q. No. 577", "cop": 3, "opa": "Total pancreatectomy", "opb": "Sphincteroplasty", "opc": "Side to side pancreatico jejunostomy", "opd": "Resetting the tail of pancreas and performing a pancreatojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2d151119-6d63-4dd3-bcf1-460d9c24afc6", "choice_type": "single"} {"question": "The ideal temperature to cool the burnt surface is", "exp": "In temperate climates cooling should be at about 15degC and hypothermia must be avoided They provide analgesia and delay the micro vascular damage in burns It should occur for a minimum of 20 minutes and is effective upto 1 hour after burn injury. Paicularly impoant in scalds Ref: Bailey and love 27th edition Pg no : 620", "cop": 2, "opa": "10degC", "opb": "15degC", "opc": "20degC", "opd": "25degC", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8a59cf42-1525-4884-98cd-8a3259260b6b", "choice_type": "single"} {"question": "Azygous vein drains into", "exp": "course and termination of azygos vein - The azygos vein enters the thorax by passing through the aoic opening of the diaphragm, The azygos vein then ascends up to fouh thoracic veebra where it arches forwards over the root of the right lung and ends by joining the posterior aspect of the superior vena cava just before it pierces the pericardium Ref : B D Chaurasia's Human Anatomy, seventh edition, volume 1 , pg. no. 233", "cop": 3, "opa": "IVC", "opb": "Coronary sinus", "opc": "SVC", "opd": "Right atrium", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "66f05ad5-da39-44a1-b242-1e947790e8ce", "choice_type": "single"} {"question": "Remnant of notochord is", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:60As the embryo enlarges, the notochord elongates considerably and lies in the Midline, in the position to be later occupied by the veebral column. However, the notochord doesn&;t give rise to the veebral column. Most if it disappears, but pas of it persist in the region of each interveebral disc as the nucleus purposes.", "cop": 2, "opa": "Annulus fibrosus", "opb": "Nucleus pulposus", "opc": "Ligament flavum", "opd": "Interansverse ligament", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8be6ac8e-94e2-4a65-a208-f268db6986ac", "choice_type": "single"} {"question": "Gitter cells are", "exp": "Microglia are a type of neuroglia (glial cell) located throughout the brain and spinal cord. Microglia account for 10-15% of all cells found within the brain. As the resident macrophage cells, they act as the first and main form of active immune defense in the central nervous system (CNS). Microglia (and other neuroglia including astrocytes) are distributed in large non-overlapping regions throughout the CNS. Microglia are key cells in overall brain maintenance--they are constantly scavenging the CNS for plaques, damaged or unnecessary neurons and synapses, and infectious agents. Since these processes must be efficient to prevent potentially fatal damage, microglia are extremely sensitive to even small pathological changes in the CNS. This sensitivity is achieved in pa by the presence of unique K+ channels that respond to even small changes in extracellular potassium. Ref - Wikipedia.org", "cop": 1, "opa": "Microglia", "opb": "Modified macrophages", "opc": "Astrocytes", "opd": "Neutrophils", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4bef0501-4e65-4b5f-8ebd-9fad8da71f3d", "choice_type": "single"} {"question": "Bosophillic stippling is seen in", "exp": "Refer robbins 8/e p406 Lead poisoning is a type of metal poisoningcaused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, inability to have children, and tingling in the hands and feet. It causes almost 10% of intellectual disability of otherwise unknown cause and can result in behavioral problems. Some of the effects are permanent. In severe cases anemia, seizures, coma, or death may occur Associated conditionsEdit Thalassemia (b-thalassemia Minor (i.e Trait) & Major, and a-thalassemia, only when 3 gene loci defective: (--/-a)) Severe megaloblastic anemia Hemolytic anemia Sickle-cell anemia Pyrimidine 5' nucleotidase deficiency Alcoholism Myelodysplastic syndromes Sideroblastic anemia Congenital dyserythropoietic anemia Primary myelofibrosis Leukemia Erythroleukemia Hemorrhage, e.g. from gastrointestinal tract CPD-choline phosphotransferase deficiency Unstable hemoglobins Altered hemoglobin biosynthesis Heavy metal poisoning Lead poisoning Zinc Arsenic Silver Mercury", "cop": 2, "opa": "Cadmium Poisoning", "opb": "Lead Poisoning", "opc": "Chromium poisoning", "opd": "Iron poisoning", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "020a7178-d44c-4709-8445-116e0f64dbaa", "choice_type": "single"} {"question": "Middle meningeal aery arises from", "exp": "Middle meningeal aeryIt is typically the third branch of the first pa (retromandibular pa) of the maxillary aery, one of the two terminal branches of the external carotid aery.After branching off the maxillary aery in the infratemporal fossa, it runs through the foramen spinosum to supply the dura mater and the calvaria.The middle meningeal aery is the largest of the three (paired) aeries which supply the meninges, the others being the anterior meningeal aery and the posterior meningeal aery.", "cop": 4, "opa": "Middle cerebral aery", "opb": "Superior temporal aery", "opc": "Facial aery", "opd": "Maxillary aery", "subject_name": "Anatomy", "topic_name": null, "id": "286e03f2-e4a5-4ca2-a940-5cadcece0a9f", "choice_type": "single"} {"question": "Most commonly seen Choledochal cyst", "exp": "Most common Choledochal cyst Type I>Type IV >Type III Type I is the most common It is the dilation of extrahepatic biliary tree Type Ia: cystic dilation Type Ib: Focal segmental dilation Type Ic : Fusiform dilation Treatment : Roux-en-Y hepatic jejunostomy Ref: Sabiston 20th edition 1510-1511", "cop": 1, "opa": "Type I", "opb": "Type II", "opc": "Type III", "opd": "Type IV", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b98a20ca-f1fa-4bb2-aa0d-f4429d1be83b", "choice_type": "single"} {"question": "Structures present in Radical neck node resection", "exp": "Radical neck dissection (RND) was attributed to Crile in 1906 and was considered the gold standard for the removal of nodal metastases (Fig. 33-4). Through a subsequent close reading of Crile's surgical notes, it was found that he had begun to modify his surgical technique to remove only selected regions of the neck, depending on the site of the primary tumor; this has become common surgical practice for HNSCC at the present time. All modifications of neck dissection are described in relation to the standard RND, which removes nodal levels I through V and the sternocleidomastoid muscle, internal jugular vein, cranial nerve XI, cervical plexus, and submandibular gland. Preservation of the sternocleidomastoid muscle, internal jugular vein, or cranial nerve XI in any combination is referred to as a modified RND, and the structures preserved are specified for nomenclature. A modified neck dissection may also be referred to as a Bocca neck dissection, named after the surgeon who demonstrated that not only is modi- fied RND equally as effective in controlling neck disease as RND when structures are preserved that are not directly involved in tumor, but also the functional outcomes of patients after modified RND are superior to functional outcomes after RND.18 Although resection of the sternocleidomastoid muscle or one internal jugular vein is relatively nonmorbid, loss of cranial nerve XI leaves a denervated trapezius muscle, which can cause a painful chronic frozen shoulder. RND or modified RND can be performed for removal of detectable nodal disease. Preservation of any of levels I through V during neck dissection is referred to as selective neck dissection and is based on knowledge of the patterns of spread to neck regions. Selective neck dissection is performed on a clinically negative (N0) neck, with preservation of nodal groups carrying less than a 20% chance of being involved with metastatic disease. Regional control has been shown to be as effective after selective neck dissection as after modified RND in patients with a clinically negative neck. Studies evaluating treatment of an N0 neck inves- tigated the use of sentinel lymph node biopsy, which attempts to predict the disease status of the neck based on the first echelon of nodes that drain the tumor.19 Although sentinel lymph node biopsy has been used extensively with melanoma, its use in HNSCC has come about more gradually. Early results using iso- sulfan blue dye alone suggested that this technique cannot con- sistently identify the sentinel node in HNSCC. More recent results using a gamma probe were more encouraging, although the isolated node should be serial step-sectioned at a thickness of 150 nm and be examined through permanent processing. Recom- mendations at the present time are that the technique should be restricted to early-stage (T1 or T2) oral and oropharyngeal cancers, with clinically N0 necks; the gamma probe continues to be an investigational tool pending validation by large randomized clini- cal trials. Ref: sabiston 20th edition Pgno: 794", "cop": 1, "opa": "Vagus nerve", "opb": "Spinal accessory nerve", "opc": "Internal jugular vein", "opd": "Sternocleidomastoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ca5a0b59-ec26-4aa6-9ace-17f4821291c4", "choice_type": "single"} {"question": "Structures passing through the centre of the cavernous sinus", "exp": null, "cop": 4, "opa": "Occulomotor nerve", "opb": "Trochlear nerve", "opc": "Maxillary nerve", "opd": "Abducent nerve", "subject_name": "Anatomy", "topic_name": null, "id": "cd73e9ab-24cb-48ad-ba16-d355b8cb219a", "choice_type": "single"} {"question": "Stomach is supplied by", "exp": "The left gastric aery is a branch of celiac trunk. The left gastroepiploic aery supplies left half of greater curvature of the stomach is a branch of splenic aery. The sho gastric aeries that supply the fundus are also branches of the splenic aery. The right gastroepiploic aery that supplies the right half of greater curvature of the stomach is a branch of gastroduodenal aery.Reference: clinical anatomy for students a problem-solving approach, Neeta v Kulkarni, page no 615, 616.", "cop": 4, "opa": "Celiac trunk", "opb": "Splenic aery", "opc": "Gastroduodenal aery", "opd": "Inferior pancreaticoduodenal aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c2941c4b-5479-40af-8762-4d0820ed40d1", "choice_type": "single"} {"question": "Boundary of Morrison's pouch is formed by", "exp": "Boundaries of Morrison's pouch (Hepatorenal pouch) Anteriorly Inferior surface of right lobe of the liver Gall bladder Posteriorly Right Supra renal gland Upper pa of right kidney 2nd pa of duodenum Hepatic flexure of colon Transverse mesocolon Pa of head of pancreas Superiorly Inferior late of corornary ligament Inferiorly Opens into general peritoneal cavity Ref: Gray's 40th edition Pg no : 1101", "cop": 1, "opa": "Kidney", "opb": "Falciform ligament of liver", "opc": "Spleen", "opd": "Pancreas", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "71ea2ec3-16f4-4774-b686-81de89a5d8bd", "choice_type": "single"} {"question": "The virulence factor of P.aeruginosa , endotoxin A acts by", "exp": "It prevents protein synthesis by inhibiting elongation factor 2", "cop": 2, "opa": "Type 3 secretion system", "opb": "Inhibiting protein syntesis", "opc": "Acts on toll like receptors", "opd": "Biofilm formation", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "7dfdf19d-847f-4a57-a404-a4ef8f3c8549", "choice_type": "single"} {"question": "Biceps brachi is supplied by", "exp": "Root value of musculocutaneous nerve is C5, C6.It arises from the lateral cord of brachial plexus.B D Chaurasia 7th edition Page no : 57", "cop": 3, "opa": "Radial nerve", "opb": "Median nerve", "opc": "Musculocutaneous nerve", "opd": "Axillary nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "56b89fbe-e3d8-4078-9695-153d2684a883", "choice_type": "single"} {"question": "buimia nervosa is treated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 4, "opa": "pimozide", "opb": "clozapine", "opc": "reserpine", "opd": "escitalopram", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "24c99f3a-c50f-46e2-8f8b-38106dd09256", "choice_type": "single"} {"question": "Early indication of sexual maturation in females is", "exp": "The onset of pubey is triggered by various genetic and environmental factors. The activation of the hypothalamic-pituitary-gonadal axis leads to the production of gonadotropins ( LH & FSH) and sex steroids (estrogen & testosterone). Pubey in girls stas with Breast development (thelarche)- 8-13yrs Appearance of public hair(pubarche) At last menstruation ( menarche)- average at 12.6 yrs( range 10-16 yrs) Pubey in boys stas with Increase in testicular size(9-14yrs) Pubarche Lengthening of penis Spermarche( production of sperms at 14-16 yrs) Ref: Ghai, 9th edition, Chapter 5, Page 60.", "cop": 2, "opa": "Menarche", "opb": "Thelarche", "opc": "Pubarche", "opd": "Genital maturation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fb375323-947a-42f0-afd8-17c256b59c82", "choice_type": "single"} {"question": "The HLA class3 region genes are impoant element in", "exp": "Ref Robbins 9/e p215 Anantha Narayana 6/e p108 Class III molecules include several secreted proteins with immune functions: components of the complement system (such as C2, C4, and B factor), cytokines (such as TNF-a, LTA, and LTB), and heat shock proteins.", "cop": 2, "opa": "Translate rejection phenomenon", "opb": "Governing susceptibility to autoimmune disease", "opc": "Immune surveillance", "opd": "Antigen presentation and elimination", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "35cc5fdd-c430-4e3d-8ea3-38854ac2c33e", "choice_type": "single"} {"question": "Investigation to diagnosis of laryngopharyngeal reflux", "exp": "pH monitoring at the level of pharynx is not helpful because the acid refluxed is neutralised by the pharyngeal secretions Hence a dual (bifurcated) catheter measuring both pH and impedance is used across upper oesophageal sphincter thereby permitting detection of pharyngeal reflux Ref: Shackelford 8th edition Pgno: 222", "cop": 2, "opa": "Esophageal pH monitoring", "opb": "Dual probe impedance pH monitoring", "opc": "Barium esophagram", "opd": "Scintigraphy", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "c765910b-3a0e-4760-be52-8de7110483a9", "choice_type": "single"} {"question": "Structures passing through middle pa of superior orbital fissure", "exp": "superior orbital Lateral pa: Lacrimal and frontal nerves, trochlear nerve, superior ophthalmic vein, meningeal branch of lacrimal aery, anastomotic branch of middle meningeal aery which anastomoses with recurrent branch of lacrimal aery middle pa Upper and lower divisions of oculomotor nerve, nasociliary nerve, abducent nerve Medial pa Inferior ophthalmic vein; sympathetic nerve from plexus around internal carotid aery Ref BDC volume 3;Sixth edition pg 56", "cop": 2, "opa": "Trochlear nerve", "opb": "Nasociliary nerve", "opc": "Lacrimal nerve", "opd": "Trigeminal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1f28265d-86e7-4deb-91a7-66476131fad9", "choice_type": "single"} {"question": "Parakeratinization is seen in", "exp": "B. i.e. Non - keratinized stratified squamous epithelium", "cop": 2, "opa": "Keratinized stratified squamous epithelium", "opb": "Non keratinized stratified squamous epithelium", "opc": "Transitional epithelium", "opd": "Simple squamous epithelium", "subject_name": "Anatomy", "topic_name": null, "id": "437aa8ec-9c90-49a8-9782-ac15d5cd8f1a", "choice_type": "single"} {"question": "Obturator aery is a branch of", "exp": "Obturator aery is the branch of internal iliac aery that passes anterio - inferiorly on the lateral wall of the pelvis,to the upper pa of obturator foramen and escaping the pelvic cavity through the obturator canal, it divides both into anterior and posterior branch. ref - BDC 6e vol2 pg63 imageref - teachmeanatomy.com", "cop": 1, "opa": "Internal iliac aery", "opb": "External iliac aery", "opc": "Common iliac aery", "opd": "Vesical aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "b0d0072c-69e9-4351-9871-ff5a4cffb645", "choice_type": "single"} {"question": "Tongue muscles are derived from", "exp": "Inderbir Singh&;s Human embryology Tenth edition Pg 176 The musculature of tongue is derived from occipital myotomes", "cop": 1, "opa": "Occipital somites", "opb": "Pharyngeal pouch", "opc": "Hypobranchial emminence", "opd": "Neural crest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2af1fb13-8c75-473c-b805-fcf860fb0c2b", "choice_type": "single"} {"question": "The hardest and calcified pa of tooth is known as", "exp": "Enamel is the densely calcified white material covering the crown of the tooth. It is the hardest substance in the body and made up of crystalline prisms.The prisms lie at right angles to the tooth surface.Pulp is the inner core containing soft tissue, blood vessels, nerve, and lymphatics.Pulp is covered by a layer of tall columnar cells called odontoblasts. The space-occupying pulp is called pulp cavity.Dentine is a calcified material surrounding the pulp cavity. It forms the basis of the tooth and contains spiral tubulesradiating from the pulp cavity. Each tubule is occupied by a protoplasmic process from the odontoblast. In dentine, calcium and organic matter are in the same propoion as bone.Cementum is the bony covering over the neck and root of tooth. It commonly overlaps the lower pa of enamel.Reference: Textbook of anatomy, Head Neck, and Brain, Vishram Singh, 2nd edition, page no.184", "cop": 3, "opa": "Pulp", "opb": "Dentin", "opc": "Enamel", "opd": "Cementum", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "8370aaa5-0765-4236-a2c7-281479701e0b", "choice_type": "single"} {"question": "Fertilization of sperm & ova takes place at", "exp": null, "cop": 1, "opa": "Ampullae", "opb": "Infundibulum", "opc": "Isthmus", "opd": "Fimbrial End", "subject_name": "Anatomy", "topic_name": null, "id": "d57e842b-5319-4a82-871e-81f86b2acd5f", "choice_type": "single"} {"question": "Most common site of biopsy in amyloidosis", "exp": "Ref Robbins 9/e p261 Kidney. Amyloidosis of the kidney is the most common and most serious feature of the disease. Grossly, the kidney may appear unchanged, or it may be abnormally large, pale, gray, and firm; in long-standing cases, the kidney may be reduced in size. Microscopically, the amyloid deposits are found principally in the glomeruli, but they also are present in the interstitial peritubular tissue as well as in the walls of the blood vessels. The glomerulus first develops focal deposits within the mesangial matrix and diffuse or nodular thickenings of the basement membranes of the capillary loops. With progression, the deposition encroaches on the capillary lumina and eventually leads to total obliteration of the vas- cular tuft (Fig. 4-34, A). The interstitial peritubular deposits frequently are associated with the appearance of amorphous pink casts within the tubular lumens, presumably of a pro- teinaceous nature. Amyloid deposits may develop in the walls of blood vessels of all sizes, often causing marked vascular narrowing. renal biopsy is useful in the presence of urinary abnormalities. Rectal and gingival biopsy specimens contain amyloid in as many as 75% of cases with generalized amyloidosis. Examination of abdominal fat aspirates stained with Congo red is a simple, low-risk method. In suspected cases of AL amyloi- dosis, serum and urinary protein electrophoresis and immunoelectrophoresis should be performed.", "cop": 3, "opa": "Liver", "opb": "Spleen", "opc": "Kidney", "opd": "Lung", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f7908ee0-725a-4a00-8833-6d36c9db4dad", "choice_type": "single"} {"question": "The synthesis of one peptide bond involves hydrolysis of", "exp": "During the translation process, the formation of one peptide bond (adding one amino acid) consumes 4 high energy phosphates (2 from ATP & 2 from GTP). Eukaryotes will add 6 amino acids and prokaryotes will add 18 amino acids per second. (Refer: Harper's Illustrated Biochemistry, 26th edition, pg no: 370)", "cop": 2, "opa": "1 ATP & 3 GTP", "opb": "2 ATP & 2 GTP", "opc": "3 ATP & 1 GTP", "opd": "4 ATP", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7c94d6e9-f0c9-434e-8c3a-cc17159554da", "choice_type": "single"} {"question": "The vein formed by union of posterior division of retromandibular vein and posterior auricular vein is", "exp": "External jugular vein is formed by posterior auricular vein and posterior division of retromandibular vein.", "cop": 3, "opa": "Common facial vein", "opb": "Anterior jugular vein", "opc": "External jugular vein", "opd": "Interior jugular vein", "subject_name": "Anatomy", "topic_name": null, "id": "291956aa-8bba-40f7-8cd6-94414b5a5440", "choice_type": "single"} {"question": "According to Bismuth classification, type IV Cholangiocarcinoma involves", "exp": "Bismuth - corlette classification of Hilar Cholangiocarcinoma Type I- Tumor confined to hepatic duct, not involving the main biliary confluence Type II- Tumor involving the main biliary confluence but not extending to the right or left ducts Type IIIa- Tumor extending upto the right secondary biliary confluence Type IIIb- Tumor extending upto the left secondary biliary confluence Type IV - Tumor extending bilaterally to the secondary biliary confluence Ref : Sabiston 20th edition Pgno :1514-1518", "cop": 3, "opa": "Common hepatic duct", "opb": "Bifurcation only", "opc": "Bifurcation and bilateral secondary intrahepatic ducts", "opd": "Bifurcation and unilateral secondary intrahepatic ducts", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7949b883-fff3-45a6-bf33-df60ba2c2eec", "choice_type": "single"} {"question": "The kinetic energy of the body is least in one of the following phases of walking cycle;", "exp": "Ans. is 'b' i.e. MidstanceRef.: Gray's 38th/e p 898 & 899According to Gray's- \"In walking each foot is on the ground (stance phase) for about 60% of the stride and off (swing phase) for about 40%. Thus single support phases (one foot on the ground) alternate with double support phases (two foot).\"Gray's further states- \"The speed and so the kinetic energy of the body passes through a maximum in each double-support phase and a minimum in each single support phase.\"Here are various phases of waling cycle:Double Support phases of the walking - Heel Strike cycle includes - - Foot flatToe flatSingle limb support phases of the - Mid stance walking cycle includes - - Heel offMid swingSo the answer is obvious now because the only single limb support phase in the question is mid stance.", "cop": 2, "opa": "Heel strike.", "opb": "Mid-stance", "opc": "Double support", "opd": "Toe-off", "subject_name": "Anatomy", "topic_name": "Joints", "id": "fe3998f2-3fbe-4f40-a006-17b3826f2d5a", "choice_type": "single"} {"question": "The forward displacement of the tibia and the femur is prevented by", "exp": "Structurally knee is a weak joint because the aicular surfaces are not congruent. The tibial condyles are too small and shallow to hold the large convex femoral condyles in place. The stability of the joint is maintained by a number of factors:-1.cruciate ligaments-anteroposterior stability. 2.Collateral ligaments-side to side stability.3.Iliotibial tractCRUCIATE LIGAMENTS: Very thick and strong fibrous bands. Direct bonds of union between tibia and fibula. Maintain anteroposterior stability of knee joint. Anterior cruciate ligament:- Begins from anterior pa of intercondylar area of tibia, runs upward, backward and laterally and is attached to the posterior pa of medial surface of lateral condyle of femur. Taut during extension of knee. The anterior cruciate ligament is more commonly damaged than the posterior.It may be injured in violent hyperextension of knee or anterior dislocation of tibia. Posterior cruciate ligament:- Begins from posterior pa of intercondylar area of tibia, runs upwards, forwards and medially and is attached to lateral surface of medial condyle of femur. Taut during flexion of knee. The posterior cruciate ligament is injured in posterior dislocation of tibia. Both these are supplied by middle genicular nerves and vessels. {Reference: BDC 6E pg no.143}", "cop": 1, "opa": "Anterior cruciate ligament", "opb": "Posterior cruciate ligament", "opc": "Medial collateral ligament", "opd": "Lateral collateral ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "879a6360-c43f-442a-b229-699f717779b3", "choice_type": "single"} {"question": "Coagulation defect associated with increased coagulation are seen in", "exp": "Ref Harrison 16/e p1491 ,9/e p123 Protein C and protein S are two vitamin K-dependent proteins that act in a complex to proteolytically inacti- vate cofactors Va and VIIIa. Protein C activation by thrombomodulin was described earlier; protein S is a cofactor for protein C activity Resistance to activated protein C due to the factor V R506Q (Leiden) mutation is the most common clotting abnormality in patients with venous thromboembolism", "cop": 4, "opa": "Increased protein C", "opb": "Increased protein S", "opc": "Increased anti thrombin 3", "opd": "Protein C resistance", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e82ac2dc-bfb4-413f-94c4-9e3f193d73c0", "choice_type": "single"} {"question": "Thoracic duct does not drain", "exp": "Thoracic duct does not drain right upper half above the diaphragm B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION,Page no-286", "cop": 1, "opa": "Right upper pa of body", "opb": "Left upper pa of body", "opc": "Right lower pa of body", "opd": "Left lower pa of body", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "6dab85d8-37c2-4d86-8614-80b6aed12d85", "choice_type": "single"} {"question": "Root value of intercostobrachial nerve is", "exp": "The intercostobrachial nerve is a lateral cutaneous branch of the second intercostal nerve that supplies sensation to the skin of the Axilla . It leaves the second intercostal space at the midaxillary line and subsequently pierces the serratus anterior muscle to enter the subcutaneous tissues of the axilla. The nerve may be injured during axillary surgery such as nodal clearance for breast cancer The anterior divisions of the second, third, fouh, fifth, and sixth thoracic nerves, and the small branch from the first thoracic, are confined to the walls of the thorax, and are named thoracic intercostal nerves respectively . They pass forward in the intercostal spaces below the intercostal vessels. At the back of the chest they lie between the pleura and the posterior intercostal membranes, but soon they run between the internal intercostals and the innermost intercostals then anteriorly they lie between the pleura and the internal intercostals . Ref - radiology assistant.com", "cop": 2, "opa": "T1", "opb": "T2", "opc": "T3", "opd": "T4", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d30749ac-d52c-4276-88f1-3b580c251ea7", "choice_type": "single"} {"question": "Nodular regenerative changes in liver most commonly occur in", "exp": "Refer Robbins page no 876", "cop": 1, "opa": "Drugs induced hepatitis", "opb": "Alcoholic hepatitis", "opc": "Hepatitis B", "opd": "Autoimmune hepatitis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fd874d5f-2b2c-48b8-88af-f78974cf753a", "choice_type": "single"} {"question": "Anterior relation of left kidney", "exp": "Anterior Relations - (1) Left suprarenal gland, (2) spleen, (3) stomach, (4) pancreas, (5) splenic vessels, (6) splenic flexure and descending colon, and (7) jejunum. Out of these the gastric, splenic and jejunal surfaces are covered by peritoneum. The lateral border of the left kidney is related to the spleen and to the descending colon Ref : B D Chaurasia's Human Anatomy , seventh edition, volume 2 , pg. no. 343", "cop": 4, "opa": "Liver", "opb": "Duodenum", "opc": "Ascending colon", "opd": "Pancreas", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "73900d10-f718-4b51-94d1-ee8a8456ee41", "choice_type": "single"} {"question": "Passavant's ridges is formed by", "exp": null, "cop": 1, "opa": "Palatopharyngeus muscle", "opb": "Palatoglossus muscle", "opc": "Stylopharageus muscle", "opd": "Buccinator muscle", "subject_name": "Anatomy", "topic_name": null, "id": "54e0e776-37ef-4f68-b749-53a1876f7391", "choice_type": "single"} {"question": "Angle of mandible is supplied by", "exp": "Auriculotemporal nerve arises by two roots which run backward, encircle the middle meningeal aery, and unite to form a single trunk. The nerve continues backward between the neck of the mandible and the sphenomandibular ligament above the maxillary aery. Behind the neck of the mandible, it turns upwards and ascends on the temple behind the superficial temporal vessels. Ref BDC volume 3; 6th edition pg 125", "cop": 3, "opa": "Greater auricular nerve", "opb": "Lesser occipital nerve", "opc": "Auriculotemporal nerve", "opd": "Trigeminal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "06caedf4-10b9-41e6-bb46-3155ec6354aa", "choice_type": "single"} {"question": "Superficial branch of ulnal nerve supplies to the following muscle", "exp": "Superficial branch of ulnar nerve supplies the palmaris brevis muscle and divides into 2 digital branches for the medial 1 1/2 digits . Adductor pollicis, opponens digiti minimi and abductor digiti minimi is supplied by the deep branch of ulnar nerve. Ref - BD Chaurasia 7th edition Page no: 124", "cop": 2, "opa": "Adductor pollicis", "opb": "Palmaris brevis", "opc": "Abductor digit minimi", "opd": "Opponens digiti mini", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "ed6db92f-628d-4145-a52b-8938d6e8eafb", "choice_type": "single"} {"question": "Prion disease is caused by", "exp": "ref Robbins 9/e p1281 Prion diseases are caused by misfolded forms of the prion protein, also known as PrP. ... The human forms of prion disease are most often the names Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gesmann-Straussler-Scheinker syndrome (GSS), kuru and variably protease-sensitive prionopathy (VPSPr", "cop": 1, "opa": "Misfolding of protein", "opb": "Denaturation of Protein", "opc": "Reduced formation of protein", "opd": "Excess formation of protein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "567f8d48-1b67-4a9f-bd48-a6b87508a1ab", "choice_type": "single"} {"question": "Renal papillary necrosis is almost associated with the following condition", "exp": "Refer p 936 Most common cause of papillary necrosis is diabetes mellitus Acute papillary necrosis is most often a complication of acute pyelonephritis in diabetes. Chronic papillary necrosis is seen in assoscation with analgesic nephropathy", "cop": 1, "opa": "Diabetes mellitus", "opb": "analgesicnephroathy", "opc": "Chronic pyelonephritis", "opd": "Post streptococcal GN", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8e5ff119-eab5-4212-9d5a-0bb10604566c", "choice_type": "single"} {"question": "Arrange covering on peripheral nerve from inner to outer", "exp": "Covering on peripheral nerve from inner to outer is Endoneurium, perineurium, Epineurium INDERBIR SINGH&;S TEXT BOOK OF HUMAN HISTOLOGY PAGE NO:171", "cop": 2, "opa": "Endoneurium, Epineurium, perineurium", "opb": "Endoneurium, perineurium, Epineurium", "opc": "Perineurium, Endoneurium, Epineurium", "opd": "Epineurium, Endoneurium, perineurium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "880e42cd-e93e-41ac-be56-9d2e39aaf234", "choice_type": "single"} {"question": "Most common malignant tumor of parotid gland is", "exp": "The major salivary glands include the parotid glands, subman- dibular glands, and sublingual glands. There are also approxi- mately 750 minor salivary glands scattered throughout the submucosa of the oral cavity, oropharynx, hypopharynx, larynx, parapharyngeal space, and nasopharynx. Salivary gland neoplasms are rare and constitute 3% to 4% of head and neck neoplasms. Most neoplasms arise in the parotid gland (70%), whereas tumors of the submandibular gland (22%) and sublingual and minor salivary glands (8%) are less common Malignant Salivary gland tumors Acinic cell carcinoma Mucoepidermoid carcinoma Adenoid cystic carcinoma Polymorphous low-grade adenocarcinoma Epithelial-myoepithelial carcinoma Basal cell adenocarcinoma Sebaceous carcinoma Papillary cystadenocarcinoma Mucinous adenocarcinoma Oncocytic carcinoma Salivary duct carcinoma Adenocarcinoma Myoepithelial carcinoma Malignant mixed tumor Squamous cell carcinoma Small cell carcinoma Lymphoma Metastatic carcinoma Carcinoma ex pleomorphic adeno Malignant salivary tumors are staged according to size; T1 is smaller than 2 cm, T2 is 2 to 4 cm, T3 is larger than 4 cm (or any tumor with macroscopic extraparenchymal extension), and T4 involves invasion of surrounding tissues. Malignant salivary tumors are listed in Box 33-1. Mucoepidermoid carcinoma is the most common malignant tumor of the parotid gland and can be divided into low-grade and high-grade tumors. High-grade lesions have a propensity for regional and distant metastases and corre- sponding shoer survival rates than low-grade mucoepidermoid carcinomas Ref: Sabiston 20th edition Pgno: 807", "cop": 1, "opa": "Mucoepidermoid cancer", "opb": "Adenoid cyst cancer", "opc": "Acinic cell tumor", "opd": "Lymphoma", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d231db1c-541a-4602-9cd8-035f3498f63e", "choice_type": "single"} {"question": "Treatment for polycystic liver disease is", "exp": "Treatment of symptomatic polycystic liver disease is deroofing of the cyst Treatment Laparoscopic unroofing for small number of large cysts A combination of cyst unroofing+liver resection for reducing liver volume Most common complication specific to surgery: Ascites Ref: Sabiston 20th edition Pgno : 1469", "cop": 1, "opa": "Deroofing of the cyst", "opb": "Injection of sclerosant", "opc": "Hepatic resection", "opd": "Liver transplantation", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6489b67b-9783-433f-9562-566a1d620538", "choice_type": "single"} {"question": "Halocrine secretion is seen in .....gland", "exp": "The manner in which their secretions are poured out of the cells: Merocrine: In most exocrine glands secretions are thrown out of the cells by a process of exocytosis, the cell remaining intact, this manner of secretion is described as merocrine, e.g., goblet cell (sometimes also called eccrine or epicrine), Apocrine: In some glands the apical pas of the cells are shed off to discharge the secretion, this manner of secretion is described as apocrine. An example of apocrine secretion is seen in some atypical sweat glands and in mammary glands. Holocrine: In some glands, the entire cell disintegrates while discharging its secretion. This manner of discharging secretion is described as holocrine, and is seen typically in sebaceous glands. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no., 58.", "cop": 3, "opa": "Salivary", "opb": "Mammary", "opc": "Sebaceous glands", "opd": "Gastric", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c928e479-1015-4286-a42a-577945e95e61", "choice_type": "single"} {"question": "Structures not passing through inferior cerebellar peduncle", "exp": "The fibres entering or leaving the cerebellum are grouped to form three peduncles which connect the cerebellum to the midbrain,the pons and the medulla. CONSTITUENTS OF THE CEREBELLAR PENDUNCLE Penducle Afferent tracts Efferent tracts A) Superior cerebellar peduncle 1) Anterior spinocerebellar 2) Tectocerebellar 1)Cerebellorubral 2) Dentatothalamic 3) Dentatoolivary 4) Fastigioreticular B) Middle cerebellar peduncle Pontocerebellar C) Inferior cerebellar peduncle 1) Posterior spinocerebellar 2) Cuneocerebellar 3) Parolivocerebellar 4) Olivocerebellar 5) Reticulocerebellar 6) Vestibulocerebellar 7) Anterior external arcuate fibres 8) Straie medullares 9) Trigeminocerebelar 1) Cerebellovestibular 2) Cerebelloolivary 3) Cerebelloreticular REF: B D Chaurasia's human anatomy,Vol:3, Pg:392", "cop": 3, "opa": "Pontocerebellar", "opb": "Cuneocerebellar", "opc": "Anterior spinocerebellar", "opd": "Posterior spinocerebellar", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "25cf27d0-7ec1-43bb-8207-c4b4e2ce2e50", "choice_type": "single"} {"question": "The receptor cells of the olfactory epithelium are", "exp": null, "cop": 1, "opa": "Bipolar neurons", "opb": "Unipolar neurons", "opc": "Multipolar neurons", "opd": "Stellate cells", "subject_name": "Anatomy", "topic_name": null, "id": "2d21a6f3-ae51-4442-aff8-4daea42e2f0b", "choice_type": "single"} {"question": "The angle that tympanic membrane makes with the floor of meatus is", "exp": "Tympanic membrane is placed obliquely at an angle of 55 degrees with the floor of the meatus. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 3 , pg. no., 285.", "cop": 4, "opa": "15 o", "opb": "25 o", "opc": "45 o", "opd": "55 o", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "dcd46306-9b70-4066-8e99-fef10238e2e7", "choice_type": "single"} {"question": "Muscular component of dorsal aoa develops from", "exp": "Muscular component of dorsal aoa develops from paraxial mesodermRef: Inderbir Singh&;s Human embryology Tenth edition Pg 257", "cop": 2, "opa": "Axial Mesoderm", "opb": "Paraxial Mesoderm", "opc": "Intermediate mesoderm", "opd": "Lateral plate mesoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a2dde450-f5f6-4f0d-9b14-038f4f7b450f", "choice_type": "single"} {"question": "Infection spreading via lymphatics from the lower lip first enter the blood stream at the", "exp": null, "cop": 1, "opa": "Brachiocephalic vein", "opb": "Inferior labial vein", "opc": "Inferior labial artery", "opd": "Pterygoid venous plexus", "subject_name": "Anatomy", "topic_name": null, "id": "aed83e95-9752-4f40-9cdc-c65185422582", "choice_type": "single"} {"question": "Reticulocytes are stained by", "exp": "Ref Robbins 9/e p635 Reticulocytes are stained in living state in-vitro so staining with dyes like brilliant cresyl blue and new methylene blue is preferred road supra vital staining Brilliant cresyl blue is a supravital stain used for counting reticulocytes. It is classified as an oxazine dye", "cop": 2, "opa": "Methylviolet", "opb": "Brilliant cresyl blue", "opc": "Sudan black", "opd": "Indigo carmine", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "51ed6d0c-c3b4-4ce7-91af-d459060c70ec", "choice_type": "single"} {"question": "Fastest acting schizontocidal drug among the fillowfol is", "exp": "Ref-KDT 6/e p792 Aemisinin derivatives like dihydroaemisinin,aeether and aemether etc fastest acting anti malarial drugs", "cop": 1, "opa": "Aemether", "opb": "Mefloquine", "opc": "Chloroquine", "opd": "Proguanil", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "6d4eabfd-49d4-4884-a056-54b65910c5d6", "choice_type": "single"} {"question": "The most frequently dislocated joint in the body is", "exp": "The glenohumeral joint is the most mobile joint in the body and is very unstable As the mobility increases, stability is lost in the joint The shoulder dislocation occurs more commonly in adults and rare in the children. Ref : Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 813.", "cop": 2, "opa": "Acromioclavicular joint", "opb": "Glenohumeral joint", "opc": "Ankle joint", "opd": "Hip joint", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "000f79f0-b229-4bec-9c18-01996d018d25", "choice_type": "single"} {"question": "Amphotercin B causes deficiency of", "exp": "Refer Katzung 11/e p 838 Renal tubular acidosis and renal wasting of K+ and Mg2+ also may be seen during and for several weeks after therapy. Supplemental K+ is required in one-third on patients with prolonged therapy", "cop": 3, "opa": "Sodium", "opb": "Calcium", "opc": "Potassium", "opd": "Chloride", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4c735739-72f3-44e9-b781-91f5b8f8b46b", "choice_type": "single"} {"question": "In poal venous system, valves are present at", "exp": "D i.e. The whole system is valvelessLike vena Cava, the poal vein and its tributaries are without valvesQ. The normal pressure in poal vein is 3-5 mmHg and the increase in venous pressure is distributed throughout the splanchenic circulation.", "cop": 4, "opa": "The junction of superior mesentric aery with the splenic aery", "opb": "Within the poal vein only", "opc": "In the intrahepatic poion of poal vein", "opd": "The whole system is valveless", "subject_name": "Anatomy", "topic_name": null, "id": "f03fb5f5-85ce-4b83-9b5a-70216cdadf7d", "choice_type": "single"} {"question": "The choroid plexus of the fouh ventricle is derived from the", "exp": "Roof plate & its pial covering give rise to the choroid plexus. Alar plate gives rise to sensory neurons Basal plate gives rise to motor neurons Floor plate contains decussating fibers Rhombic lips give rise to the cerebellum.", "cop": 4, "opa": "alar plate", "opb": "basal plate", "opc": "floor plate", "opd": "roof plate", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 3", "id": "97ed1259-76f6-4e3d-9b6e-ca4f0129749b", "choice_type": "single"} {"question": "There are low many pairs of spinal nerves", "exp": "Spinal nerves: spinal nerve arise in pairs 8 cervical 12 thoracic 5 lumbar 5 sacral 1 coccygealEach spinal nerve arises by a series of dorsal and ventral merve roots. these rootlets unite in or near the interveebral foramen to form spinal nerveBD CHAURASIAS HUAMAN ANATOMY Sixth edition Volume 3", "cop": 3, "opa": "28", "opb": "30", "opc": "31", "opd": "33", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2bef6162-56e7-433b-9900-2576426dbf7f", "choice_type": "single"} {"question": "In Apoptosis intiation", "exp": "Ref Robbins 9/e p56 The Death Receptor (Extrinsic) Pathway of Apoptosis Many cells express surface molecules, called death recep- tors, that trigger apoptosis. Most of these are members of the tumor necrosis factor (TNF) receptor family, which contain in their cytoplasmic regions a conserved \"death domain,\" so named because it mediates interaction with other proteins involved in cell death. The prototypic death receptors are the type I TNF receptor and Fas (CD95). Fas ligand (FasL) is a membrane protein expressed mainly on activated T lymphocytes. When these T cells recognize Fas-expressing targets, Fas molecules are cross-linked by FasL and bind adaptor proteins the death domain. These in turn recruit and activate caspase-8. In many cell types caspase-8 may cleave and activate a pro-apoptotic member of the Bcl-2 family called Bid, thus feeding into the mitochondrial pathway. The combined activation of both pathways delivers a lethal blow to the cell. Cellular proteins, notably a caspase antagonist called FLIP, block activation of caspases downstream of death receptors. Interestingly, some viruses produce homologues of FLIP, and it is suggested that this is a mechanism that viruses use to keep infected cells alive. The death receptor pathway is involved in elimination of self-reactive lympho- cytes and in killing of target cells by some cytotoxic T lymphocytes.", "cop": 1, "opa": "The death receptors induce Apoptosis when they get engaged by fas ligand system", "opb": "Cytochrome C inhibits Apoptosis activating factor", "opc": "Apoptosis may be intiated by capase activation", "opd": "Apoptosis mediated through DNA damage", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4ca18dc1-53b8-4991-a90a-8a5a5eccfcae", "choice_type": "single"} {"question": "CT severity index is a measure for", "exp": "Computed Tomography severity index(CTSI) for acute pancreatitis CTSI= Balthazar grade score + necrosis score Highest attainable score =10 CTSI score 0-3: Moality 3%,Morbidity 8% 4-6: Moality 6%, Morbidity 35% 7-10: Moality 17%, Morbidity 92% Refer CTSI table Ref: Sabiston 20th edition Pgno :1527", "cop": 2, "opa": "Hepatitis", "opb": "Pancreatitis", "opc": "Cerebral trauma", "opd": "Meningitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "12e33685-edf3-4549-9e5d-fbb68df7767e", "choice_type": "single"} {"question": "Parasympathetic ganglion in head are", "exp": null, "cop": 2, "opa": "Three pairs", "opb": "Four pairs", "opc": "Five pairs", "opd": "Two pairs", "subject_name": "Anatomy", "topic_name": null, "id": "ee4e0ece-5c5e-4daf-b52c-c9f4e7f3a0db", "choice_type": "single"} {"question": "Coronary cabal fistula is", "exp": "Inokuchi shunt Interpostion of vein graft between the left gastric (coronary) vein and the IVC Also known as coronary-cabal fistula Choice (TIPS or shunt) is based on the predicted time to transplantation Ref:Sabiston 20th edition Pgno : 1440", "cop": 1, "opa": "Inokuchi", "opb": "Warren's", "opc": "Eck's fistula", "opd": "Shamik", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fa6656e4-97cd-44a2-b6d3-9a58e02f79f8", "choice_type": "single"} {"question": "In a patient with compensated liver cirrhosis presented with history of variceal bleed. The treatment of choice in this patient is", "exp": "Management of variceal bleeding In addition to pharmacologic therapy endoscopy should be carried out as soon as possible If varices are found they are treated with either endoscopic ligation or sclerotherapy EVL is the treatment of choice for variceal bleeding Endoscopic scleropathy Variceal bleeding suspected based on history ABC's and resuscitation Sta vasopressin or octreotide infusion Variceal bleeding confirmed on EGD Endoscopic band ligation (or scleropathy) If bleeding stopped - Vasopressin/octreotide for 3-5 days. Complete 7 days of antibiotics. Repeat endoscopic banding every 10-14 days until eliminated If bleeding didn't stop - Balloon tampon ade consider TIPS or surgical shunt if TIPS fails or not vavilable Ref: Sabiston 20th edition Pgno : 1444", "cop": 4, "opa": "Propanalol", "opb": "Liver transplantation", "opc": "TIPS(Transjugular intra hepatic poal shunt)", "opd": "Endoscopic sclerotherapy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "217bf844-948f-473e-8d62-818e1163f69e", "choice_type": "single"} {"question": "Example of type 4 hypersensitivity is", "exp": "Ref Robbins 9/e p209 Delayed-type hypersensitivity (DTH), described next, is an illustrative model of T cell-mediated inflammation and tissue injury. The same reactions are the underlying basis for several diseases. Contact dermatitis is an example of tissue injury resulting from T cell-mediated inflammation. It is evoked by contact with pentadecylcatechol (also known as urushiol, the active component of poison ivy and poison oak, which probably becomes antigenic by binding to a host protein). On reexposure of a previously exposed person to the plants, sensitized TH1 CD4+ cells accumulate in the dermis and migrate toward the antigen within the epidermis. Here they release cytokines that damage kera- tinocytes, causing separation of these cells and formation of an intraepidermal vesicle, and inflammation manifested as a vesicular dermatitis. It has long been thought that several systemic diseases, such as type 1 diabetes and mul- tiple sclerosis, are caused by TH1 and TH17 reactions against self antigens, and Crohn disease may be caused by uncon- trolled reactions involving the same T cells but directed against intestinal bacteria. T cell-mediated inflammation also plays a role in the rejection of transplants, described later in the chapter. Delayed-Type Hypersensitivity DTH is a T cell-mediated reaction that develops in response to antigen challenge in a previously sensitized individual. In contrast with immediate hypersensitivity, the DTH reac- tion is delayed for 12 to 48 hours, which is the time it takes for effector T cells to be recruited to the site of antigen chal- lenge and to be activated to secrete cytokines. The classic example of DTH is the tuberculin reaction, elicited by chal- lenge with a protein extract of M. tuberculosis (tuberculin) in a person who has previously been exposed to the tuber- cle bacillus. Between 8 and 12 hours after intracutaneous injection of tuberculin, a local area of erythema and indura- tion appears, reaching a peak (typically 1 to 2 cm in diam- eter) in 24 to 72 hours and thereafter slowly subsiding. On histologic examination, the DTH reaction is characterized by perivascular accumulation (\"cuffing\") of CD4+ helper T cells and macrophages (Fig. 4-13). Local secretion of cyto- kines by these cells leads to increased microvascular per- meability, giving rise to dermal edema and fibrin deposition; the latter is the main cause of the tissue induration in these responses. DTH reactions are mediated primarily by TH1 cells; the contribution of TH17 cells is unclear. The tubercu- lin response is used to screen populations for people who have had previous exposure to tuberculosis and therefore have circulating memory T cells specific for mycobacterial proteins. Notably, immunosuppression or loss of CD4+ T cells (e.g., resulting from HIV infection) may lead to a nega- tive tuberculin response even in the presence of a severe infection. Prolonged DTH reactions against persistent microbes or other stimuli may result in a special morphologic pattern of reaction called granulomatous inflammation. The initial perivascular CD4+ T cell infiltrate is progressively replaced by macrophages over a period of 2 to 3 weeks. These accumulated macrophages typically exhibit morphologic evidence of activation; that is, they become large, flat, and eosinophilic, and are called epithelioid cells. The epitheli- oid cells occasionally fuse under the influence of cytokines (e.g., IFN-g) to form multinucleate giant cells. A micro- scopic aggregate of epithelioid cells, typically surrounded by a collar of lymphocytes, is called a granuloma (Fig. 4-14, A). The process is essentially a chronic form of TH1-mediated inflammation and macrophage activation (Fig. 4-14, B). Older granulomas develop an enclosing rim of fibroblasts and connective tissue. Recognition of a granuloma is of diagnostic impoance because of the limited number of conditions that can cause it (Chapter 2).", "cop": 2, "opa": "Farmer's lung", "opb": "Contact hypersensitivity", "opc": "Immediate hypersensitivity", "opd": "Myasthenia gravis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "05fdf61b-9b74-478f-9224-11cdde8337e9", "choice_type": "single"} {"question": "The rate of newly synthesized Osteoid mineralization is best estimated by", "exp": "Reference Robbins page no 358 6th edition Tetracycline is absorbed into bone and so it is used as a marker of bone growth for biopsies in humans. Tetracycline binds to newly formed bone at the bone interface where it shows as a linear fluroscencse. Tetracycline labelling is used to determine the amount of bone growth within a ceain period of time", "cop": 1, "opa": "Tetracycline labelling", "opb": "Alizarine red staining", "opc": "Calceine stain", "opd": "Von Kossa stain", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "efedd892-b9d5-4643-8357-90bfb8cd69c8", "choice_type": "single"} {"question": "Enchondroma commonly arises from", "exp": "ENCHONDROMA * Rarely an enchondroma may extend through the coex and demonstrate a exophytic growth pattern. This is known as an enchondroma protuberans, and may either be seen sporadically or as pa of Oilier disease. * Almost all enchondromas are located in the medullary cavity of tubular bones. D/ds: * bone infarct , chondrosarcoma, intraosseous * other benign Ivtic bone lesions, * metastases * granulomatous disease : sarcoidosis, tuberculosis * X-ray & CT Typically enchondromas are small 1 - 2cm lytic lesions with non-aggressive features. narrow zone of transition sharply defined scalloped margins : may have mild endosteal scalloping expansion of the overlying coex may be present but there should not be coical breakthrough unless fractured Chondroid calcifications may be present : rings and arcs calcification-STIPPLED/PUNCTATE/POPCORN no periosteal reaction * The majority of enchondromas more frequ the metaphyseal region entirely arise in A cailaginous lesion in an epiphysis is more likely to be a chondrosarcoma . Refer Apleys 9th/e p 197", "cop": 4, "opa": "Ribs", "opb": "Veretebre", "opc": "Tibia", "opd": "Phalanges", "subject_name": "Anatomy", "topic_name": null, "id": "5a5a1137-5007-4d26-ae8d-555384238f5b", "choice_type": "single"} {"question": "Inflammatory mediator of generalised systemic inflammation is", "exp": "ref Robbins 8/e p57 ; 61 ,7/e p71 ,9/e p86", "cop": 1, "opa": "IL1", "opb": "IL2", "opc": "Interferon alpha", "opd": "TNF", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3a89b456-6ead-496b-9376-a050efb2aca5", "choice_type": "single"} {"question": "Direct coombs test detects", "exp": "Refer robbins 8/e p653 A Coombs test (also known as antiglobulin test or AGT) is either of two clinical blood tests used in immunohematology and immunology. The two Coombs tests are the direct Coombs test (DCT, also known as direct antiglobulin test or DAT), and the indirect Coombs test (also known as indirect antiglobulin test or IAT). The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. Since these antibodies sometimes destroy red blood cells, a person can be anemic and this test can help clarify the condition. The indirect Coombs detects antibodies that are floating freely in the blood. These antibiodies could act against ceain red blood cells and the test can be done if you have had a blood transfusion and might be having a reaction to the blood", "cop": 4, "opa": "Antigens in serum", "opb": "Antibodies on RBC surface", "opc": "Antigen on RBC surface", "opd": "Antibodies in serum", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "ba46147f-cd22-44e4-8ac7-a10238949023", "choice_type": "single"} {"question": "Intrinsic muscle of the tongue is derived from", "exp": "The muscles develop from the occipital myotomes which are supplied by the hypoglossal nerve Notes: The intrinsic muscles of tongue are- 1. Superior longitudinal 2.Inferior longitudinal 3.Transverse 4.Veical Ref BDC volume 3,Sixth edition pg 270", "cop": 3, "opa": "2nd branchial cleft", "opb": "Pharyngeal arch mesenchyme", "opc": "Occipital somites", "opd": "Cervical somites", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "c1805875-7c03-4cc1-a3a7-a5d3332945e4", "choice_type": "single"} {"question": "Muscle entering middle ear from pyramid apex is", "exp": "A conical projection, called the pyramid, lies near the junction of the posterior and medial walls of the middle ear. It has an opening at its apex for passage of the tendon of the stapedius muscle.Ref: BD Chaurasia; 6th edition; Volume 3", "cop": 1, "opa": "Stapedius", "opb": "Tensor tympani", "opc": "Tensor palatine", "opd": "Auricularis", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9d938dc9-68bc-4a77-b0b0-a1a61b3d6681", "choice_type": "single"} {"question": "Amnion is made up of", "exp": "Amnion is made up of Amniogenic cells+ Somatopleuric cells", "cop": 2, "opa": "amniogenic cells+splanchnopleuric cells", "opb": "amniogenic cells+somatopleuric cells", "opc": "primary yolk cells+somatopleuric cells", "opd": "primary yolk sac +splanchnopleuric cells", "subject_name": "Anatomy", "topic_name": "General Embryology 1", "id": "dff3ef35-186f-4a99-9812-1c2537c80b2d", "choice_type": "single"} {"question": "lithium was introduced by", "exp": "LITHIUM - Lithium was introduced by ==== JOHN F CADE - It is liver friendly drug - It is mainly eliminated by kidney Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, 935", "cop": 3, "opa": "benedict morel", "opb": "delay and denniker", "opc": "john F Cade", "opd": "bleuler", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "0e023286-c3b3-47bb-a042-6adb359f5581", "choice_type": "single"} {"question": "Deep petrosal nerve is formed from", "exp": "The deep petrosal nerve,sympathetic in nature is a branch of the sympathetic plexus around the internal carotid aery.It contains postganglionic fibres from the superior cervical sympathetic ganglion. Ref,BDC VOL.3,Fouh edition", "cop": 1, "opa": "Symathetic plexus around carotid", "opb": "Facial nerve", "opc": "Glossopharyngeal", "opd": "Internal carotid plexus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "3b3d94ad-260c-403a-9c67-76b0cbe9b8d7", "choice_type": "single"} {"question": "Intermediate filaments in connective tissue", "exp": "Vimentin is the intermediate filaments present in connective tissue It is used as tumor marker in tumor of connective tissue Ref:Guyton and Hall textbook of medical physiology 12th edition,page number 8,9,14", "cop": 3, "opa": "Keratin", "opb": "Desnin", "opc": "Vimentin", "opd": "Lamin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b1fcf268-d303-4aa4-9c6e-4045a65158e3", "choice_type": "single"} {"question": "Antegrade cholecystectomy", "exp": "Types of Cholecystectomy Retrograde Hilar structure dissection occurs first followed by the removal of gallbladder in the triangle of callot's Antegrade or Fundus first or Top-down Seperates GB from the liver before the cystic duct and aery are ligated Considered safer because it allows for the progressive demonstration of the anatomy down to the indundibulocystic junction Ref: Mastery of surgery 5th edition Pg no : 1128", "cop": 1, "opa": "Stas from fundus", "opb": "Stas from cystic duct identification", "opc": "Stas from hilar dissection", "opd": "Considered unsafe", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d02d4d5e-ae94-42b3-81ff-80206da70db9", "choice_type": "single"} {"question": "Somites are derived from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:62 Some details about the paraxial mesoderm -at first, the cells of the paraxial mesoderm are homogeneously arranged .later, the mesoderm gets segmented -the segment is of two categories, somitomeres, and somites", "cop": 1, "opa": "Paraxial mesoderm", "opb": "Lateral plate mesoderm", "opc": "Intermediate mesoderm", "opd": "Mesoblastic nephroma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9877d936-c503-4c40-b6b6-de1d6a1ed556", "choice_type": "single"} {"question": "conveing of psychological syptoms to physical presentation was given by", "exp": "CONTRIBUTIONS OF FREUD o Father of psychoanalysis He founded a type of psychotherapy called psychoanalysis. It is nothing but analyzing the psych(MIND) o Interpretation of dreams According to Freud dreams are royal road to unconscious In dreams several conflicts that are present in the unconscious comes to the consciousness in the form of dreams Thus by analyzing ones dreams we could understand the unconscious conflicts o Psychosexual stages of life o Freud divided development into 5 stages namely psycho sexual development o It is divivded namely oral , anal , phallic, latent, genital phase. o Conversion disorders conversion disorder is conveing a psychological pain to physical symptoms present physical symptoms which has some connection with unconscious conflict is called SYMBOLIZATION present physical symptoms which has some resemblance with illness in family members, which is called MODELLING patient has illness like neurological deficit but they have apparent in concern towards their own illness which is known as LA BELLE INDIFFERENCE main defense mechanism in conversion disorder is REPRESSION o Repression defence mechanism * REPRESSION is called QUEEN of defense mechanisms o COUCH and FREE ASSOSIATION * He introduced a technique called as a couch technique where he makes the patient lie on the couch, he asks the patient to speak from 'cabbages to kings. This method is called FREE ASSOSIATION. By allowing the patient to speak whatever that comes to their mind randomly so that by analyzing their thoughts we could understand the conflict in the unconscious. o Topographical theory of mind Freud gave topographical theory mind It is divided into pre conscious, unconscious, conscious Later he disregarded topographical theory of mind and gave structural theory of mind o Structural theory of mind It is divided into id, ego, super ego Id= instinctual desires like anger, hunger, sexual instinct Ego= function of mind to work based on ego to avoid guilt from super ego Super ego= based on moral principle, obtained from family members and relatives, teachers Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition pg no. 845", "cop": 4, "opa": "erikson", "opb": "adler", "opc": "lorenz", "opd": "freud", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "c704bd06-5523-4d7a-8120-2623f154358c", "choice_type": "single"} {"question": "Umbilical cord has", "exp": "This tube of amnion and the structures within it constitutes the umbilical cord.T his cord contains two umbilical aeries and one umbilical vein. REF HUMAN EMBRYOLOGY; Inderbier singh; Tenth edition; Page 67", "cop": 3, "opa": "2 veins and 1 aery", "opb": "1 aery and 1 vein", "opc": "2 aeries and 1 vein", "opd": "2 aeries and 2 veins", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f847a093-d8ff-4583-acba-7188f1273155", "choice_type": "single"} {"question": "Sympathetic trunk rests on", "exp": "The sympathetic trunk lies just lateral to the veebral bodies for the entire length of the veebral column. ... The sympathetic trunk permits preganglionic fibers of the sympathetic nervous system to ascend to spinal levels superior to T1 and descend to spinal levels inferior to L2/3 The superior end of it is continued upward through the carotid canal into the skull, and forms a plexus on the internal carotid aery ; the inferior pa travels in front of the coccyx, where it converges with the other trunk at a structure known as the ganglion impar . Along the length of the sympathetic trunk are sympathetic ganglia known as paraveebral ganglia . Image showing efferrent system of sympathetic trunk Ref - medscape.com", "cop": 1, "opa": "Body of veebra", "opb": "Transverse process", "opc": "Lamina of veebra", "opd": "Pedicle of veebra", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "e7d361ed-6445-461b-b3e1-b45de1bd813d", "choice_type": "single"} {"question": "Huhle cells are seen in", "exp": "Refer Robbins page no 1087thyroid is often diffusely enlarged, although more localized enlargement may be seen in some cases. The capsule is intact, and the gland is well demarcated from adjacent structures. The cut surface is pale, yellow-tan, firm, and somewhat nodular. There is extensive infiltration of the parenchyma by a mono- nuclear inflammatory infiltrate containing small lympho- cytes, plasma cells, and well-developed germinal centers (Fig. 24-11). The thyroid follicles are atrophic and are lined in many areas by epithelial cells distinguished by the presence of abun- dant eosinophilic, granular cytoplasm, termed Huhle cells. This is a metaplastic response of the normally low cuboidal follicular epithelium to ongoing injury. In fine-needle aspiration biopsy samples, the presence of Huhle cells in conjunction with a heterogeneous population of lymphocytes is character- istic of Hashimoto thyroiditis. In \"classic\" Hashimoto thyroiditis, interstitial connective tissue is increased and may be abundant. Unlike Reidel thyroiditis (see later), the fibrosis does not extend beyond the capsule of the gland.", "cop": 2, "opa": "Granulomatous thyroid disease", "opb": "Hashimotos thyroiditis", "opc": "Papillary carcinoma of thyroid", "opd": "Thyroglossal duct", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "52be9363-0c65-42bd-b426-e540c5a0f200", "choice_type": "single"} {"question": "Lower 1/3 of vagina is formed by", "exp": "Lower 2/3rd of vagina formed from sinovaginal bulb which comes from endoderm of urogenital sinus. Upper 1/3rd of vagina is derived from fused paramesonephric duct. Mesonephric duct forms the collecting pa or ductular pa of male reproductive system. Mesoderm of Mullerian duct is basically paramesonephric duct.", "cop": 3, "opa": "Mesonephric duct", "opb": "Paramesonephric duct", "opc": "Sinovaginal bulb", "opd": "Mesoderm of mullerian duct", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "83d19023-2a1e-461b-b90a-b033af147a08", "choice_type": "single"} {"question": "Angular vein communicates with", "exp": "Angular Vein is the upper most segment of the Facial Vein, formed by the union of the Supratrochlear Vein and Supraorbital Vein. It runs obliquely downward by the side of the nose, is linked with the cavernous sinus by the superior and inferior ophthalmic veins which are devoid of valves. fig:-Angular vein communication with cavernous sinus", "cop": 1, "opa": "Cavernous sinus", "opb": "Superior sagittal sinus", "opc": "Inferior sagittal sinus", "opd": "Straight Sinus", "subject_name": "Anatomy", "topic_name": "Abdomen: Miscellaneous", "id": "b6cb4dfb-9530-447b-b1d1-a90e6e991d4f", "choice_type": "single"} {"question": "Nucleus ambiguous doesn&;t include", "exp": "The nuclei of facial nerve are located in the pons.Nucleus ambiguous is an elongated column of typical motor neurons extending throughout the medulla.The fibres from nucleus ambiguous supplies muscles derived from 3,4 and 6 branchial arches. Cells in nucleus ambiguous contain motor neurons associated with three cranial nerves (rostral pole -C.N. IX glossopharyngeal; middle pa -C.N. X vagus; caudal pole -C.N. XI spine accessory).(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 94)", "cop": 1, "opa": "7th nerve nucleus", "opb": "9th nerve nucleus", "opc": "10th nerve nucleus", "opd": "11th nerve nucleus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "8ac0ab89-6f27-4b3f-aa82-178b32af925e", "choice_type": "single"} {"question": "Last to recover in spinal anesthesia is", "exp": ".", "cop": 4, "opa": "Pain", "opb": "Motor", "opc": "Proprioception", "opd": "Preganglionic", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e850a5fb-42d6-44f4-92eb-8ae9cb6484ad", "choice_type": "single"} {"question": "Leucine aminopeptidase is elevated in obstruction of", "exp": "Leucine Aminopeptidase Increased leucine aminopeptidase (Lap) activity is seen in : Carcinoma of the pancreas, choledocholithiasis, acute pancreatitis Viral hepatitis, cirrhosis, carcinoma with liver metastases In common bile duct obstruction, whether due to carcinoma pancreas or choledocholithiasis, the elevated serum Lap levels returned to normal following relief of the obstruction. This is in agreement with the hypothesis that the increased serum LAP activity in these conditions is the result of bile duct obstruction Ref: American journal of Gastroenterology, Dec 1963, vol 41 issue 6 Pgno : 620", "cop": 3, "opa": "Ureter", "opb": "Urethra", "opc": "Common bile duct", "opd": "Spermatic cord", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "cb1e6fc9-3f46-4dd6-8ac0-ba608f14c341", "choice_type": "single"} {"question": "The intiating mechanism in endotoxic shock is", "exp": "Ref Robbins. 9/e p132-133 Endothelial injury is also a cause..see the above questions In gram-negative sepsis, free LPS attaches to a circulating LPS-binding protein, and the complex then binds to the CD14 receptor on monocytes, macrophages, and neutrophils. Engagement of CD14 (even at doses as minute as 10 pg/mL) results in intracellular signaling an associated \"Toll-like receptor\" protein 4 (TLR-4). This signaling results in the activation of nuclear factor kappaB (NF-kB), which leads to transcription of a number of genes that trigger a proinflammatory response. It was the result of significant activation of mononuclear cells and synthesis of effector cytokines. It also results in profound activation of mononuclear cells and the production of potent effector cytokines such as IL-1, IL-6, and TNF-a. TLR-mediated activation helps to trigger the innate immune system to efficiently eradicate invading microbes, but the cytokines they produce also act on endothelial cells. There, they have a variety of effects, including reduced synthesis of anticoagulation factors such as tissue factor pathway inhibitor and thrombomodulin. The effects of the cytokines may be amplified by TLR-4 engagement on endothelial cells", "cop": 4, "opa": "Peripheral vasodilation", "opb": "Endothelial injury", "opc": "Increased vascular permeability", "opd": "Cytokine release", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8fe21cce-6639-4ace-a59f-9c4b1a720bef", "choice_type": "single"} {"question": "The best test for oesophageal varices is", "exp": "Endoscopy - upper GI endoscopy represents the most reliable single technique as it shows oesophageal varix and bleeding point Dilated longitudinal veins running a Zig- Zag course Diffuse oesophagal spasm is best diagnosed by Manometry Commonest cause of acute upper GI haemorrhage - Peptic ulcer ref - Srb's manual of surgery 5e p790", "cop": 2, "opa": "CT- scan", "opb": "Gastro- oesophagoscopy", "opc": "Tomography", "opd": "Ultrasound", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5f426c3a-9bcf-4c67-a981-184fc26199fd", "choice_type": "single"} {"question": "Gingival biopsy is useful in the diagnosis of", "exp": "Ref Harrison 17/ 2146; Robbins 9/e p 262,7/e p264 Other Organs. Amyloidosis of other organs generally is encountered in systemic disease. The adrenals, thyroid, and pituitary are common sites of involvement. In such cases as well, the amyloid deposition begins in relation to stromal and endothelial cells and progressively encroaches on the paren- chymal cells. Surprisingly large amounts of amyloid may be present in any of these endocrine glands without apparent disturbance of function. In the gastrointestinal tract, a rela- tively ored site for deposition, amyloid may be found at all levels, sometimes producing tumorous masses that must be distinguished from neoplasms. Nodular depositions in the tongue may produce macroglossia. On the basis of the frequent involvement of the gastrointestinal tract in systemic cases, gingival, intestinal, and rectal biopsies serve in the diag- nosis of suspected cases. Deposition of b2-microglobulin amyloid in patients receiving long-term dialysis occurs most commonly in the carpal ligaments of the wrist, resulting in compression of the median nerve (leading to carpal tunnel syndrome).", "cop": 2, "opa": "Sarcoidosis", "opb": "Amyloidosis", "opc": "Histoplasmosis", "opd": "Scurvy", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "add848af-f9df-4b22-b62c-194714698ad4", "choice_type": "single"} {"question": "Muscles attached to the greater tubercle of humerus", "exp": "Supraspinatus is attached to greater tubercle. All other muscles are attached in the shaft of humerus. B D Chaurasia 7th edition Page no : 16 mnemonic:attachments in greater tubercle of humerus SIT Supraspinatus Infraspinatus Teres Minor", "cop": 1, "opa": "Supra spinatus", "opb": "Latissimus dorsi", "opc": "Teres major", "opd": "Pectoralis major", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "bead0164-caee-45fc-95b1-e194386dbdbd", "choice_type": "single"} {"question": "In the lungs bronchial aeries supply the bronchopulmonary tree", "exp": "Bronchial aery supplies the bronchial tree till respiratory bronchiole. BD CHAURASIA'S HUMAN ANATOMY VOLUME 1. 6TH EDITION.page no.242 fig 16.9", "cop": 3, "opa": "Till teiary bronchi", "opb": "Till segmental bronchi", "opc": "Till respiratory bronchioles", "opd": "Till alveolar sacs", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "7f91be07-5d10-4837-8f5a-65996e35b72e", "choice_type": "single"} {"question": "Clara cells are present in", "exp": "cells of Clara - Some non-ciliated cells present predominantly in terminal bronchioles produce a secretion that spreads over the alveolar cells forming a film that reduces surface tension. These include the cells of Clara. Some functions attributed to cells of Clara include: Protection against harmful substances that are inhaled. Protection against development of emphysema by opposing the action of substances (proteases) that tend to destroy walls of lung alveoli. Stem cell function. REF : Inderbir Singh's Textbook of Human Histology, Seventh edition, pg.no. 235.", "cop": 3, "opa": "Alveoli", "opb": "Bronchus", "opc": "Bronchioles", "opd": "Trachea", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c7ab6ff6-88fe-445c-825e-990e3a320a33", "choice_type": "single"} {"question": "Endothelial derived relaxing factor is associated with", "exp": "Ref Robbins 8/p60;7/e,72-73 ;9/e p80 , it is firmly established this substance is nitric oxide (NO).Endothelium produces NO which then diffuses to the vascular smooth muscle tissue, although these seems to be evidence that vasodilatory may also be of neuronal origin, rather than endothelial. NO is produced by the enzyme nitric oxide synthase and it relaxes smooth muscle tissue by promotig the synthesis of cGMP.", "cop": 4, "opa": "Ras", "opb": "C- myc", "opc": "Bcl", "opd": "nNOS", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "033cc986-5bca-4869-9e63-56aa054a9d64", "choice_type": "single"} {"question": "Hb is a good buffer because of", "exp": "Ref Robbins 9/e p650 Haemoglobin also functions in CO2 and proton transpo from tissues to lungs . Release of O2 from Oxy Hb at the tissue is accompanied by uptake of proton due to lowering of the pKa of histamine residues", "cop": 1, "opa": "Histidine residues", "opb": "Protein nature", "opc": "Acidic nature", "opd": "Iron molecules", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "9e219080-5add-464c-9dd5-15aa3161ce7e", "choice_type": "single"} {"question": "Nerve supply of scalpa) Auriculotemporal nerveb) Zygomatic nervec) Occipital nerved) Infratrochlear nerve", "exp": "Nerves of the scalp and superficial temporal region\n\n\n\n\nIn Front of auricle\n\n\nBehind th auricle\n\n\n\n\nSensory nerves\n\n\nSensory nerves\n\n\n\n\n1.\n\n\n Supratrochlear branch of  the frontal (ophthalmic  division of trigeminal  nerve)\n\n\n1.\n\n\nPosterior division of great auricular nerve (C2, C3) from cervical plexus\n\n\n\n\n2.\n\n\n Supraorbital, branch of  frontal (ophthalmic  division of trigeminal  nerve)\n\n\n2.\n\n\nLesser occipital nerve (C2), from cervical plexus\n\n\n\n\n3.\n\n\n Zygomaticotemporal,  branch of zygomatic  nerve (maxillary division  of trigerninal nerve)\n \n\n\n3.\n\n\nGreater occipital nerve (C2, dorsal ramus)\n\n\n\n\n4.\n\n\nAuriculotemporal branch of mandibular division of trigeminal nerve\n \n\n\n4.\n\n\nThird occipital nerve (C3, dorsal ramus\n\n\n\n\n \n\n\nMotor nerve\n\n\n \n\n\nMotor nerve\n\n\n\n\n1.\n\n\n Temporal branch of facial  nerve\n\n\n1.\n\n\n Posterior auricular barnch  of facial nerve", "cop": 2, "opa": "ab", "opb": "abc", "opc": "acd", "opd": "bcd", "subject_name": "Anatomy", "topic_name": null, "id": "0a086e34-6f17-4a29-bc57-f626d6a4ea83", "choice_type": "single"} {"question": "The normal gain in length in a full term baby at first 6 months of life is", "exp": "At bih length : 50cms At 3 months : 60cms At 6 months: 65 cms At 1yr: 75 cms Hence gain in length in a full term baby at first 6 months of life is 15cms Ref: Ghai, 9th edition, Table 2.3", "cop": 3, "opa": "6cms", "opb": "9 cms", "opc": "15 cms", "opd": "24 cms", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8870f0f2-f2d2-464f-86e1-a139e2897da7", "choice_type": "single"} {"question": "Choledochal cyst develops due to", "exp": "Choledochal cyst Cystic dilation of the biliary ducts, more common in females Association of Choledochal cyst with biliary atresia is seen, with type 1 biliary atresia is present in most cases It is congenital and discovered on antenatal ultrasound Most widely accepted hypothesis: Abnormal pancreaticobiliary ductal junction (APBDJ) APBDJ results in reflux of pancreatic fluid into the distal common hepatic duct and results in mucosal injury, chronic inflammation and weakening of the bile duct Wall Ref: Sabiston 20th edition Pgno : 1511", "cop": 3, "opa": "Stenosis of sphincter", "opb": "Dysfunction of long circular fibre", "opc": "Congenital", "opd": "Iatrogenic", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e926952d-67e8-40ad-866f-05d966d56899", "choice_type": "single"} {"question": "A 17 year old boy is admitted to the hospital after S, per abdomen examination is normal. After adequate resuscitation, his pulse rate is 80/min and BP is 110/70mmHg. Abdominal CT reveals 1cm deep laceration on the left lobe of the liver extending from the dome more than half way through the parenchyma. Appropriate mangement at this time would be", "exp": "In stable persons Conservative management is the preferred option Ref: Sabiston 20th edition Pgno : 437-439", "cop": 1, "opa": "Conservative management", "opb": "Abdominal exploration and packing of hepatic wounds", "opc": "Abdominal exploration and ligation of left hepatic aery", "opd": "Left hepatectomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0addbffd-08d7-419d-b3bb-e4dfd53e7e2b", "choice_type": "single"} {"question": "Tensor fascia lata is supplied by", "exp": "Of all the nerves, that passes through greater sciatic foramen, superior gluteal N is only one that passes above piriformis muscle. After entering gluteal region. Nerve loops up over inferior margin of gluteus minimus & travels anteriorly & laterally in plane b/w gluteus medius & minimus muscle It supplies gluteus minimus - abductors at hip joint gluteus medius - medially rotates thigh Tensor fasciae latae -prevent pelvis drop on opposite swing side during walking. Nerve to quadratus femoris : Enters gluteal region through greater sciatic foramen inferior to piriformis muscle & deep to sciatic nerve. Lies anterior to plane of deep muscles. It descends along the ischium deep to tendon of obturator internus muscle & associated gemellus muscle to penetrate & innervate quadratus femoris a Supplies small branch to gemellus anterior. * Inferior gluteal nerve : Enters gluteal region through sciatic foramen inferior to piriformis muscle & along the posterior surface of sciatic nerve Penetrate & supplies gluteus maximus muscle. Sciatic nerve : Largest nerve in body & innervates all muscles in posterior compament of thigh that flex the knee & all muscles that move ankle & foot Innervates large area of skin in lower limb.", "cop": 2, "opa": "Nerve to quadratus femoris", "opb": "Superior gluteal nerve", "opc": "Inferior gluteal nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": "DNB 2018", "id": "06d144a1-e855-4a14-afbe-26b76a7e7450", "choice_type": "single"} {"question": "retrorade ejaculation is common with", "exp": "chlorpromazine is a antisychotic which is assosiated with retrograde ejaculation blue green discolouration of skin lens granulor deposits obstructive jaundice ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, p no 952", "cop": 3, "opa": "haloperidol", "opb": "risperidone", "opc": "chlorpromazine", "opd": "amisulpride", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d7b6e42a-f08f-4b0d-b119-228312becde5", "choice_type": "single"} {"question": "Valve of Hasner", "exp": "Ref BDC volume3,6th edition pg 76Nasolacrimal duct begins at the lower end of the lacrimal sac, runs downwards, backward and laterally and opens into the inferior meatus of the nose.A fold of mucous membrane called hasners valve forms an imperfect valve at the lower end of the duct.", "cop": 1, "opa": "Opening of nasolacrimal duct", "opb": "Sphenoidal sinus opening", "opc": "Frontal sinus opening", "opd": "Ethmoidal sinus opening", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "34cc11bd-e64a-4991-b4b7-a481822262ec", "choice_type": "single"} {"question": "Commonest site of occurrence of chondroblastoma", "exp": "Most commonly involved bones are proximal tibia (most common) Femur and pelvis(2nd most common) Humerus Ribs Shoulder girdles Refer Campbells 12th /e p 914", "cop": 4, "opa": "Pelvis", "opb": "Femur", "opc": "Ribs", "opd": "Proximal tibia", "subject_name": "Anatomy", "topic_name": null, "id": "d20b0159-3617-4a2f-a3b8-71f3155caf8e", "choice_type": "single"} {"question": "Efferent fibers of amygdala are", "exp": "Ans. is 'a' i.e., Stria terminalisStria terminalis forms the efferent fibers of amygdaloid nucleus passing in the roof of inferior horn and floor of body of lateral ventricle.", "cop": 1, "opa": "Stria terminalis", "opb": "Striavascularis", "opc": "Lamina terminalis", "opd": "Mosseyfibers", "subject_name": "Anatomy", "topic_name": null, "id": "cb8fa6ae-cda9-4665-8788-f557636f2217", "choice_type": "single"} {"question": "Puppe's rule is", "exp": "Two fracture lines will never cross( puppe's rule) . Applying this rule it is easy to find out the sequence of injuries, i,e which fracture has occured first. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 162", "cop": 3, "opa": "Two fracture lines cross at right angles", "opb": "Two fracture lines cross at acute angle", "opc": "Two fracture lines never cross each other", "opd": "Two fracture lines cross at obtuse angle", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "2cd5e28d-ae42-4582-a479-f7967a6cc473", "choice_type": "single"} {"question": "The United Nations General Assembly recently declared June 21st as", "exp": ".", "cop": 1, "opa": "International Yoga day", "opb": "International Tourism day", "opc": "International Meditation day", "opd": "International Cultural Heritage day", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "320a9e87-37c7-48ec-942a-64fa10d17b90", "choice_type": "single"} {"question": "Common carotid artery is palpable at", "exp": null, "cop": 1, "opa": "Upper border of thyroid cartilage", "opb": "Upper border of cricoid cartilage", "opc": "At hyoid bone", "opd": "Lower border of cricoid cartilage", "subject_name": "Anatomy", "topic_name": null, "id": "0fb11510-a2f1-4059-bb49-39e7cfaa392e", "choice_type": "single"} {"question": "Follman's balanitis is seen in", "exp": "Syphilitic balanitis of Follmann (SBF) is a rare condition that is considered as manifestation of primary syphilis. Syphilitic balanitis of Follmann presents with variable clinical appearances, and primary chancre may be absent, associated with, or occur after the balanitis. Usually the inguinal lymphadenopathy is present, and syphilitic serology is positive or is going to become positive. Treatment is identical to that of primary syphilis.", "cop": 4, "opa": "Candida", "opb": "Trichomonas", "opc": "HIV", "opd": "Syphilis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e66beca6-7125-4e18-b483-19a8befcf1c7", "choice_type": "single"} {"question": "Buccopharyngeal membrane consist of", "exp": "There is no mesoderm in the prochordal plate, so this region remains relatively thin, and later forms the buccopharyngeal membrane. The buccopharyngeal membrane breaks at 4th week . The mouth is bidermal in development. It is derived paly from the stomatodeum (ectodermal) and paly from the cranial pa of the foregut (endodermal). Hence its epithelial lining is paly ectodermal and paly endodermal and the demarcation between the two is buccopharyngeal membrane. Ref: Inderbir Singh's Human Embryology, eleventh edition, pg. no.,68,69,163.", "cop": 4, "opa": "Mesoderm and endoderm", "opb": "Ectoderm and mesoderm", "opc": "Ectoderm, mesoderm and endoderm", "opd": "Endoderm and ectoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "65b5e82a-f5f3-4a7a-9d7e-4e71ef8722f0", "choice_type": "single"} {"question": "Elastic cailage is found in", "exp": "Distribution of Elastic Cailage - It forms the 'skeletal' basis of the auricle (or pinna) and of the lateral pa of the external acoustic meatus. The wall of the medial pa of the auditory tube is made of elastic cailage. The epiglottis and two small laryngeal cailages (corniculate and cuneiform) consist of elastic cailage. The apical pa of the arytenoid cailage contains elastic fibres but the major poion of it is hyaline. NOTE - All the sites mentioned above are concerned either with the production or reception of sound. REF : Inderbir Singh's Textbook of Human Histology, Seventh edition, pg.no.,85.", "cop": 1, "opa": "Auditory tube", "opb": "Nasal septum", "opc": "Aicular cailage", "opd": "Costal cailage", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "93456a18-305f-492c-8553-4decf934b792", "choice_type": "single"} {"question": "The mechanism of anti cancer action of fluoruracil is", "exp": "5-FU is an antimetabolite.it us a thymidine analogue and acts by conversion to 5'-dUMP .latter inhibits the formation of dTMP and result in Thymineless dealth of cells Ref-KDT 6/824", "cop": 3, "opa": "Cross linking of double standard DNA and the resulting inhibition of DNA replication and transcription", "opb": "Cytotoxicity resulting from metabolite that interferes with the production of dTMP", "opc": "Irreversible inhibition of dihydrofolic acid reductase", "opd": "Selective action of DNA polymerase", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "275bc554-253b-408f-acd0-22ff6406385d", "choice_type": "single"} {"question": "Gyrus not on the lateral aspect is", "exp": "(C) Cingulate gyrus # Cingulate cortex, a part of the limbic cortex, is a part of the brain situated in the medial aspect of the cerebral cortex.> Cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus.> Cingulate cortex is usually considered part of the limbic lobe.> It receives inputs from the thalamus and the neocortex, and projects to the entorhinal cortex via the cingulum. It is an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory.> Combination of these three functions makes the cingulate gyrus highly influential in linking behavioral outcomes to motivation (e.g. a certain action induced a positive emotional response, which results in learning).> This role makes the cingulate cortex highly important in disorders such as depression and schizophrenia. It also plays a role in executive function and respiratory control.> Superior temporal gyrus is one of three (sometimes two) gyri in the temporal lobe of the human brain, which is located laterally to the head, situated somewhat above the external ear.", "cop": 3, "opa": "Superior temporal gyrus", "opb": "Middle frontal gyrus", "opc": "Cingulate gyrus", "opd": "Inferior frontal gyrus", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "812fd53c-5db3-4d3e-ad1e-d94def839038", "choice_type": "single"} {"question": "Iloprost in pulmonary aerial hypeension is administered", "exp": "Ref Harrison 19 th ed pg 1666 Iloprost is a prostacyclin analogue approved inhalation for treatment of pulmonary aerial hypeension (PAH) Epoprostinil as iv treprostinil as oral /iv/SC/inhalation.", "cop": 4, "opa": "Intravenous", "opb": "Intramuscular", "opc": "Oral", "opd": "Inhalation", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "1168b961-e7f5-4856-91dd-78af78b05e94", "choice_type": "single"} {"question": "Internal anal sphincter is a pa of", "exp": "Internal anal sphincter is formed by thickened circular muscle coat of the anal canal (which is continuous with rectum) and surrounds the upper two-third of the canal.", "cop": 2, "opa": "Internal longitudinal fibers of rectum", "opb": "Internal circular muscle fibers of rectum", "opc": "Puborectalis muscle", "opd": "Deep perineal muscles", "subject_name": "Anatomy", "topic_name": "Pelvis and Perineum 3", "id": "13ef9fae-b12b-4a1d-b9cb-5d69060be9a3", "choice_type": "single"} {"question": "Anterior cruciate ligaments prevents", "exp": "CRUCIATE LIGAMENTS: Very thick and strong fibrous bands.Direct bonds of union between tibia and fibula. Maintain anteroposterior stability of knee joint. Anterior cruciate ligament:- Begins from anterior pa of intercondylar area of tibia, runs upward, backward and laterally and is attached to the posterior pa of medial surface of lateral condyle of femur. Taut during extension of knee. The anterior cruciate ligament is more commonly damaged than the posterior. It may be injured in violent hyperextension of knee or anterior dislocation of tibia. Posterior cruciate ligament:- Begins from posterior pa of intercondylar area of tibia, runs upwards, forwards and medially and is attached to lateral surface of medial condyle of femur. Taut during flexion of knee. The posterior cruciate ligament is injured in posterior dislocation of tibia. Both these are supplied by middle genicular nerves and vessels. {Reference: BDC 6E pg no.143}", "cop": 3, "opa": "Anterior dislocation of femur", "opb": "Posterior dislocation of femur", "opc": "Anterior dislocation of tibia", "opd": "Posterior dislocation of tibia", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "a27957dd-9889-48b9-bfc3-3e9ce8014a9b", "choice_type": "single"} {"question": "Major blood supply of pectoralis major muscles is", "exp": "Major blood Supply of Pectoralis major muscles is thoracoacromial trunk. The intercostal perforators arising from the internal mammary aery provide a segmental blood supply BD CHAURASIA'S HUMAN ANATOMY.VOLUME 1. 6TH EDITION.PAGE NO 180. TABLE A1.5:aeries of upper limb", "cop": 1, "opa": "Thoracoacromial trunk", "opb": "Lateral thoracic aery", "opc": "Internal mammary aery perforating branches", "opd": "Axillary aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "1ff5565d-6732-44ad-bf06-2aef028757c9", "choice_type": "single"} {"question": "In the inflammatory process the prostaglandins E1and E2 causes", "exp": "ref Robbins 9/e p85", "cop": 1, "opa": "Vasodilation", "opb": "Increased gastric output", "opc": "Decreased body temperature", "opd": "Vaso constriction", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a09dec0c-bdde-43b1-8520-84f075f161e4", "choice_type": "single"} {"question": "Paramesonephric duct in males remains as", "exp": "The paramesonephric ducts remain rudimentary in the maleThe greater pa of each duct eventually disappearsThe cranial end of each duct persists as a small rounded body attached to the testis(appendix of testis)It has been considered that the prostatic utricle represents the uterovaginal canalRef: Inderbir Singh&;s Human embryology; Tenth edition; Pg 300", "cop": 1, "opa": "Prostatic utricle", "opb": "Prostatic uretha", "opc": "Colliculus seminalis", "opd": "Ejaculatory duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bb9e9fc3-46aa-409a-bd4e-b18725e775d0", "choice_type": "single"} {"question": "Vaginal epithelium is a derivative of", "exp": "The wall of the vagina from the lumen outwards consists firstly of the mucosa of non keratinized stratified squamous epithelium with an underlying lamina propria of connective tissue, secondly a layer of smooth muscle with bundles of circular fibers internal to longitudinal fibers, and thirdly an outer layer of connective tissue called the adventitia. ref - BDC 6e vol2 pg395", "cop": 2, "opa": "Mesoderm of urogenital sinus", "opb": "Endoderm of urogenital sinus", "opc": "Mesoderm of genital ridge", "opd": "Endoderm of genital ridge", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "1d9714bf-f1cf-4fd1-9263-0f1e97732e7f", "choice_type": "single"} {"question": "Treatment of Chlamydia pneumonia is", "exp": "Although few controlled trials of treatment have been repoed, C. pneumoniae is inhibited in vitro by erythromycin, tetracycline, azithromycin, clarithromycin, gatifloxacin, and gemifloxacin. Recommended therapy consists of 2 g/d of either tetracycline or erythromycin for 10-14 days.. Ref Harrison 19th edition pg 1147", "cop": 1, "opa": "Erythromycin", "opb": "Ceftriaxone", "opc": "Penicillin", "opd": "Sulphonamide", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "b64f4a70-cb88-4d71-be7a-0bced8dbfc2f", "choice_type": "single"} {"question": "With anal canal rectum forms an angle of", "exp": "The lumen of the rectum terminates at the pelvic floor and is continued, downwards and posteriorly, as the anal canal, passing through the levator ani muscle sheet and surrounded by the internal and external anal sphincters. The anal canal is 2.5 to 5 cm in length and 3 cm in diameter when distended. The axis of the rectum forms almost a right angle (average 82 degrees) with the axis of the anal canal. It has been established by radiological studies that the anal canal is an antero-posterior slit in the resting state. Ref -pubmed.com", "cop": 3, "opa": "60 degree", "opb": "45 degree", "opc": "90 degree", "opd": "120 degree", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e2ff33fd-466a-41a3-80a3-682ab6f0281a", "choice_type": "single"} {"question": "Cause of death in amyloidosis involving kidney", "exp": "Ref Robbins 8/e p254,9/e p261 Amyloidosis of the kidney is the most common and potentially the most serious form of organ involvement", "cop": 2, "opa": "Cardiac failure", "opb": "Renal failure", "opc": "Sepsis", "opd": "Liver failure", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7be8be71-a1a8-4a57-a739-72999f62e751", "choice_type": "single"} {"question": "Korsakoff s syndrome is due to deficiency of", "exp": "Wernickes encephalopathyis a triad of GLOBAL CONFUSION, OPHTHALMOPLEGIA AND ATAXIA It is due to deficiency of thiamine It is 100% reversible Most impoant symptom needed for the diagnosis is confusion If the patients wernickes encephalopathy is not trated it would result in koraskoff's psychosis koraskoff's psychosis is a misnomer it is associated with confabulation that is fluent plausible lying, where the patient fills up with memory gaps with information and she is not aware that wat is she is saying is not truth Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition,pg no.624", "cop": 1, "opa": "Thiamine", "opb": "niacine", "opc": "riboflavine", "opd": "pyridoxine", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "f55d9c47-1003-41a7-ab96-9ca0aeb92f76", "choice_type": "single"} {"question": "The most common type of anorectal malformation is", "exp": "The most common type of malformation involving the anal canal and rectum is anorectal agenesis, in which the rectum ends as a blind sac above the puborectalis muscle. The anal canal may form normally but does not connect with the rectum. This malformation is accompanied by various fistulas.", "cop": 3, "opa": "Imperforate anus", "opb": "Anal agenesis", "opc": "Anorectal agenesis", "opd": "Rectal atresia", "subject_name": "Anatomy", "topic_name": "Embryology and abdominal wall layer", "id": "64a16fc7-73ea-4e76-a34a-1653d0e8c48a", "choice_type": "single"} {"question": "Skin of dorsum of first web space of foot is supplied by", "exp": "DEEP PERONEAL:- Muscular branches to muscles of anterior compament of leg:Tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus teius.Extensor digitorum brevis Cutaneous: dorsal digital nerves for adjacent sides of big toe and second toe.Aicular branches:Ankle joint, tarsal joints, tarsometatarsal joints and metatarsophalangeal joint of big toe. {Reference:BDC 6E vol2 pg166 }", "cop": 3, "opa": "Sural nerve", "opb": "Saphenous nerve", "opc": "Deep peroneal nerve", "opd": "Lateral plantar nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "0a38685e-e678-4411-ac1c-72c2b3678208", "choice_type": "single"} {"question": "Seminoma corresponds to", "exp": "Seminoma A seminoma typically has a cut surface that is homogeneous and pinkish cream in colour. It appears to compress neighbouring testicular tissue. It corresponds to dysgerminoma of ovaries. It consists of oval cells with clear cytoplasm and large, rounded nuclei with prominent acidophilic nucleoli. Sheets of cells resembling spermatocytes are separated by a fine fibrous stroma. Active lymphocytic infiltration of the tumour suggests a good host response and a better prognosis. There are two histological variants, one with a more anaplastic appearance and another that is characterised by cells that closely resemble different phases of maturing spermatogonia (spermatocytic seminoma). Seminomas metastasise mainly the lymphatics and haematogenous spread is uncommon. The lymphatic drainage of the testes is to the para-aoic lymph nodes near the origin of the gonadal vessels. The contralateral para-aoic lymph nodes are sometimes involved by tumour spread, but the inguinal lymph nodes are affected only if the scrotal skin is involved. Ref: Bailey and love 27th edition Pgno : 1506", "cop": 2, "opa": "Choriocarcinoma", "opb": "Dysgerminoma", "opc": "Granulosa tumour", "opd": "Luteal cyst", "subject_name": "Anatomy", "topic_name": "Urology", "id": "94206d3e-cd44-4abc-839a-387a1763de7c", "choice_type": "single"} {"question": "The whiff test is useful in the diagnosis of", "exp": "Bacterial vaginosis AMSEL criteriaNugent criteriaThin, white, yellow, homogeneous discharge.Clue cells on microscopy.pH of vaginal fluid >4.5.Release of a fishy odor on adding alkali--10% potassium hydroxide (KOH) solution (Whiff test)At least three of the four criteria should be present for a confirmed diagnosis.Grade 1 (Normal): Lactobacillus morphotypes predominate.Grade 2 (Intermediate): Mixed flora with some Lactobacilli present, but Gardnerella or Mobiluncus morphotypes also present.Grade 3 (Bacterial Vaginosis): Predominantly Gardnerella and/or Mobiluncus morphotypes. Few or absent Lactobacilli.(Refer: Novak's Textbook of Gynaecology, 23rd edition)", "cop": 2, "opa": "Trichomonas", "opb": "Bacterial vaginosis", "opc": "Candida", "opd": "PID", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0bffa6d8-3738-4116-8018-727b62805a52", "choice_type": "single"} {"question": "Drug of choice for ADHD is", "exp": ".", "cop": 1, "opa": "Methylphenidate", "opb": "Modafinil", "opc": "Amitriptyline", "opd": "Adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "68f71e37-a2a5-44ef-9139-71914b863fa4", "choice_type": "single"} {"question": "Ewings sarcoma arises from", "exp": "Refer Robbins page no 8/e 1232 Ewing sarcoma is a malignant bone tumor characterized by primitive round cells without obvious differentiation. Recently, Ewing sarcoma and primitive neuroectodermal tumor (PNET) have been unified into a single category: the Ewing sarcoma family tumors (ESFT) based on shared clinical, morphologic, biochemical and molecular features (discussed later). Although PNET demonstrates more neu- roectodermal differentiation than Ewing sarcoma, the dis- tinction is not clinically significant", "cop": 3, "opa": "G cells", "opb": "Totipotent cells", "opc": "Neuroectodermal cells", "opd": "Neurons", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "36a1fb0a-4b34-45be-b4f6-b33b91a942e5", "choice_type": "single"} {"question": "Facial N. stimulation during testing of nerve indicated by contraction of muscle", "exp": "The orbicularis oris muscle is a sphincter muscle that encircles the mouth.It lies between the skin and the mucous membranes of the lips, extending upward to the nose and down to the region between the lower lip and chin.It is sometimes called the kissing muscle because it causes the lips to close and pucker. ref - BD chaurasia 6e vol3 pg 66", "cop": 4, "opa": "Temporalis", "opb": "Masseter", "opc": "Sternoleidomastoid", "opd": "Orbicularis oris", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f3776c86-33e0-4534-ae05-5cde1dc112f7", "choice_type": "single"} {"question": "Average reproductive life span of ovum is", "exp": "LH surge occurs ~ 36 hours before ovulation LH peak occur ~ 12 hours before ovulation & marks the release of Ist polar body. This mature oocyte (ovum) remain ble for feilization for ~ 24 hours.", "cop": 2, "opa": "6-12 hrs", "opb": "12-24 hrs", "opc": "24-26 hrs", "opd": "48 hrs", "subject_name": "Anatomy", "topic_name": "General Embryology 2", "id": "7f5e0db6-ce9a-4a5f-a18c-7048fb8b7fc2", "choice_type": "single"} {"question": "Abductor of vocal cord is", "exp": "The posterior cricoarytenoids are the only intrinsic muscles of the larynx which abduct the vocal cords to allow entry of air through rima glottidis to the respiratory tract below. When posterior cricoarytenoids contract muscular processes of both carotenoids rotate medially. As a result, vocal processes rotate laterally. i.e. abducting vocal cords and providing wide diamond shaped opening of the glottis. If they are paralyzed the adductor muscles of the larynx take the upper hand and the person might die due to the lack of air. Hence, the posterior cricoarytenoids are called safety muscles of the larynx.Cricothyroid tenses the vocal cords.Lateral cricoarytenoid adducts the vocal cords.Thyroarytenoid relaxes the vocal cords.Reference: Textbook of anatomy, Head neck, and brain, Vishram Singh, 2nd edition, page no.224", "cop": 2, "opa": "Cricothyroid", "opb": "Post cricoarytenoid", "opc": "Thyro arytenoid", "opd": "Lat cricoarytenoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "70a0b0ef-3cab-48db-9886-1e1dcd78df67", "choice_type": "single"} {"question": "Intermediate mesoderm will give rise to the", "exp": "Intermediate mesoderm is a subdivision of intraembryonic mesoderm that forms a longitudinal dorsal ridge called the urogenital ridge from which the kidneys and gonads develop .", "cop": 3, "opa": "Neural tube", "opb": "Hea", "opc": "Kidneys and gonads", "opd": "Somites", "subject_name": "Anatomy", "topic_name": "General Embryology 2", "id": "7a94e17c-76fa-4038-b2ad-1d4c63ec26af", "choice_type": "single"} {"question": "Abductor of vocal cords is", "exp": "Abduction of vocal cords is by Posterior cricoarytenoid only. Posterior Cricoarytenoid is a triangular muscle. - Origin: Posterior surface of the lamina of the cricoid cailage. Origin is medial to inseion. - Inseion: Its fibres pass upwards and backward to the inseed into, the anterior aspect of muscular process of the arytenoid cailage. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Thyroarytenoid", "opb": "Lateral cricoarytenoid", "opc": "Posterior cricoarytenoid", "opd": "Cricothyroid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6a95bde1-bde0-43cb-a336-bdd5b872b6ec", "choice_type": "single"} {"question": "Renal angle lies between", "exp": "Renal-angle is area located on either side of the human back between the lateral borders of the erector spinae muscles and inferior borders of the twelfth rib, so called because the kidney can be felt at this location. Ref -researchgate.net", "cop": 1, "opa": "12th rib & lateral border of sacrospinalis", "opb": "11th rib & lateral border of sacrospinalis", "opc": "12th rib & lateral border of quadratus lumborum", "opd": "11th rib & lateral border of quadratus lumborum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "269a24b2-1ad3-46b6-8715-52deda833cd7", "choice_type": "single"} {"question": "An old man enters a hospital with myocardial infarction and severe ventricular arrithmia. The antiarrhythmic drug chosen has a narrow therapeutic window. The minimum toxic plasma concentration is 1.5 times a minimum therapeutic plasma concentration. Day half life is 6 hours. It is essential to maintaining the plasma concentration about the minimum therapeutic level to prevent possible lethal arrhythmia. Of the following the most appropriate dosing regimen would be", "exp": "Ref-Katzung 10/e p40,43,44 When a drug is administered less frequently, it produces marked variation in the plasma concentrations. In this question the drug has a half life of 6 hours. If we repeat the dose at 6 hourly intervals, there will be 100% variation in the plasma concentration. More frequent dosing will minimize the variation between maximum and minimum plasma concentrations. As the margin of safety of this drug (given in the question) is very low (maximum tolerable concentration is only 1.5 times the effective concentration), constant i.v. infusion is the best route.", "cop": 4, "opa": "Once a day", "opb": "Twice a day", "opc": "Four times a day", "opd": "Constant intravenous infusion", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "7814613a-554c-469e-a0f0-e4c19fc00e12", "choice_type": "single"} {"question": "Connecting sinus between cavernous sinus and transverse sinus", "exp": null, "cop": 1, "opa": "Superior petrosal sinus.", "opb": "Inferior petrosal sinus.", "opc": "Horizontal sinus", "opd": "Horizontal sinus Vertical sinus.", "subject_name": "Anatomy", "topic_name": null, "id": "4a8cd608-d5f6-402b-9999-6f63720ac0ab", "choice_type": "single"} {"question": "The costal cailages of these ribs do not reach the sternum", "exp": "8,9,10 the ribs are joined to the next higher cailage B D CHOURASIAS HUMAN ANATOMY UPPER LIMB THORAX VOLUME, 1 SIXTH EDITION, Page no, 196", "cop": 4, "opa": "11th & 12th", "opb": "1st & 2nd", "opc": "6th & 7th", "opd": "8th, 9th & 10th", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "8227995e-8466-49ed-b96b-7db02c051a88", "choice_type": "single"} {"question": "A young patients presented with loss of sensation in sole of foot with paralysis of medial side of plantar muscles of the foot, Most likely nerve involvement is", "exp": "TIBIAL NERVE:- Root value:ventral division of ventral rami of L4,L5,S1,S2,S3 segments of spinal cord.Beginning: largest subdivision of sciatic nerve.Course: descends veically in popliteal fossa. It continues in back of leg as the neurovascular bundle with posterior tibial vessels. Lastly passes deep to flexor retinaculum of ankle joint.Branches:Muscular branches to gastrocnemius,soleus, popliteus, plantaris, FHL, FDL and Tibialis posterior.Aicular branches to superior,middle and inferior genicular .Cutaneous and vascular branch: sural nerve ,medial calcaneal branch and branch to posterior tibial aery.Terminates by dividing into medial and lateral plantar nerves.MEDIAL PLANTAR NERVE:-Muscular branches: Abductor hallucis, flexor digitorum brevis, flexor hallucis brevis and first lumbrical.Cutaneous branch: skin of medial pa of sole and medial three and a half toes.LATERAL PLANTAR NERVE:-Main trunk: flexor digitorum accessorius and abductor digiti minimi and skin of sole. Ends by dividing into superficial and deep branches.Superficial branch: lateral and medial branch Lateral branch:flexor digiti minimi brevis ,3rd plantar, 4th interossei and skin on lateral side of little toe.Medial branch: 4th interdigital cleft. Deep branch:2nd,3rd,4th lumbricals1st,2nd,3rd dorsal interossei 1st,2nd plantar interossei andAdductor hallucis. COMMON PERONEAL:-Branch of sciatic nerve Root value:L4,L5,S1,S2 Branches:Muscular branch: sho head of biceps Cutaneous:lateral cutaneous nerve of calf.Aicular: superior lateral,inferior lateral and recurrent genicular .Terminal branches: superficial and deep peroneal. SUPERFICIAL PERONEAL:-Muscular branches: peroneus longus and brevis Cutaneous branches:Digital branches to medial side of big toe,adjacent sides of 2nd and 3rd, 3rd and 4th ,and 4th and 5th toes. DEEP PERONEAL:-Muscular branches to muscles of anterior compament of leg:Tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus teius.Extensor digitorum brevis Cutaneous: dorsal digital nerves for adjacent sides of big toe and second toe.Aicular branches:Ankle joint, tarsal joints, tarsometatarsal joints and metatarsophalangeal joint of big toe. {Reference:BDC 6E vol2 pg 79}", "cop": 4, "opa": "Common peroneal nerve", "opb": "Deep peroneal nerve", "opc": "Superficial peroneal nerve", "opd": "Tibial nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "5c2666a3-14d5-40f7-90b2-554a8cdfed47", "choice_type": "single"} {"question": "Patient a known case off alcohol dependence after 3 days of last drink develops change in behaviour that he says he could see 5 cm people throwing stones at him, acts as if he is working in his workshop, frightened pacing in and out of the house with worsening more in the night. The possible diagnosis is", "exp": "Detoxification implies removal of the toxic substance from the body, this can be done by using a drug similar to alcohol and thus benzodiazepine is chosen. This is the main drug used in treatment of alcohol withdrawal despite the problem being simple withdrawal, rum fits or delirium tremens IF LIVER FUNCTION IS WITHIN NORMAL LIMITS CHOOSE CHLORDIAZEPOXIDE, AS IT HAS A SIMILAR STRUCTURAL FORMULA LIKE ALCOHOL IF LIVER FUNCTION IS ABNORMAL CHOOSE LORAZEPAM, AS IT DOES NOT WORSEN LIVER DERANGEMENTS FRONT LOADING=====patient is loaded with benzodiazepines SYMPTOM TRIGGER=== benzodiazepines is offered only as and when the withdrawal symptom arises FIXED DOSAGE====== regular fixed dosage of benzodiazepine is given in divided doses and slowly tapered so that the patient is not on any drugs by the end of 2 weeks Ref. kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no.626", "cop": 1, "opa": "Delirium tremens", "opb": "seizure disorder", "opc": "Rum fits", "opd": "wernickes encephalopathy", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "eaad465b-9e27-429b-9dfc-07259f58f124", "choice_type": "single"} {"question": "Low V4 means", "exp": "Vd means volume of distribution.It signifies the distribution of drug in the tissues.Low Vd means less drug is distributed to tissue whereas high Vd means drug is being stored in some tissue", "cop": 2, "opa": "the drug has low half life", "opb": "the drug does not accumulate in tissues", "opc": "the drug has low bioavailability", "opd": "the drug has weak plasma protein building", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "65f8e2ef-2a9b-45c8-bf07-3121fafda300", "choice_type": "single"} {"question": "Cremasteric muscle is supplied by", "exp": "CREMASTER MUSCLE:-Consists of muscle fasciculi embedded in cremasteric fascia. The fasciculi forms superficial loops from middle one-third of upper surface of inguinal ligament and deep loops from pubic tubercle, pubic crest and conjoint tendon. Fully developed in males.In females only few fibres.Muscle along with the intervening connective tissue forms a sac-like cremasteric fascia around spermatic cord and testis. Nerve supply:- genital branch of genitofemoral nerve. Action: suspend the testis and elevate it.Cremasteric reflex:-Stroking the upper pa of the medial side of the thigh there is reflex contraction of the cremaster muscle, as is evidenced by elevation and retraction of the testis. In UMN lesions above segment L1 reflex is lost. {Reference: BDC 6E vol2 pg 206}", "cop": 2, "opa": "Ilioinguinal nerve", "opb": "Genital branch of genitofemoral", "opc": "Femoral nerve", "opd": "Obturator nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "c437e0bf-2281-47b0-9f22-c1d3f3f28e9c", "choice_type": "single"} {"question": "Mirizzi's Syndrome is", "exp": "Mirriz's syndrome(Functional hepatic syndrome) It is defined as obstruction of the common hepatic duct or CBD by external compression or by erosion of stone in the Hamann pouch or cystic duct. External compression has been classified as type I where as erosion as type II Mirriz's syndrome by McSherry Ref: Sabiston 20th edition Pgno :1510", "cop": 1, "opa": "GB stone compressing common hepatic duct", "opb": "GB carcinoma invading IVC.", "opc": "GB stone causing cholecystitis", "opd": "Pancreatic carcinoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8160c48b-4811-4f16-ba36-e673abdf337d", "choice_type": "single"} {"question": "Nissl's substance is mainly", "exp": "Nissl Substance - The cytoplasm shows the presence of a granular material that stains intensely with basic dyes; this material is the Nissl substance (also called Nissl bodies or granules). When examined by EM, these bodies are seen to be composed of rough surfaced endoplasmic reticulum. The presence of abundant granular endoplasmic reticulum is an indication of the high level of protein synthesis in neurons. The proteins are needed for maintenance and repair, and for production of neurotransmitters and enzymes. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no.,164.", "cop": 4, "opa": "Histone", "opb": "Ribosomes", "opc": "DNA", "opd": "Ribonucleoprotein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b12c2df7-a8f0-464a-8932-89d9791d17a2", "choice_type": "single"} {"question": "Treatment of choice for bleeding gastric ulcer is", "exp": "Bleeding gastric ulcers. Treatment of bleeding gastric ulcers depends on their cause and location; however, the initial approach is similar to duodenal ulcers. Patients require resuscitation, monitoring, and endoscopic investigation. Up to 70% of gastric ulcers are H. pylori-positive, so an attempt should be made to control the bleeding endoscopically, with multiple biopsy specimens of the ulcer obtained to rule out malignancy and concurrently obtained biopsy specimens of the body and antrum to test for H.pylori infection. Patients whose bleeding can be controlled and who are H. pylori-positive should undergo subsequent treatment for H. pylori infection. For bleeding that cannot be controlled, operative intervention again depends on the type of gastric ulcer. In all cases, the ulcer should ideally be excised with the addition of vagotomy depending on the cause of the ulcer (mostly for intractable ulcers that are not due to H. pylori infection or NSAID usage that can be stopped). Ref: Sabiston Textbook of Surgery 20th edition Pgno: 1209", "cop": 3, "opa": "Gastrectomy", "opb": "Antrectomy", "opc": "Under running of ulcer", "opd": "Vagotomy and drainage", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1285eae3-994e-41ad-80eb-65aabf13993d", "choice_type": "single"} {"question": "cove sensitization is mainly used in", "exp": "In cove sensitization also called as imagined punishment, the individual who wants to quit alcohol will be asked to think about adverse consequences of taking alcohol like getting arrested for drunken driving or facing a accident underintoxicated state. He would be told to dream as if if he is drunk and lies intoxicated in the road and has to be brought back to the home by family members where he will be given lot of advice from neighbours and there would be a loss of respect. While these imagined exposure the patient feels bad and makes sure thet he should quit alcohol and his thoughts ahgainst alcohol increases. Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 2, "opa": "schizoid personality", "opb": "substance use", "opc": "mania", "opd": "schizophrenia", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "1e56cddc-84bc-4477-8158-96251e523e4c", "choice_type": "single"} {"question": "Magistrate inquest deals under", "exp": "Magistrate inquest done in cases of Death in prisons Death of a person in police custody or while under police interrogation Man missing in police custody Death due to police firing Death of a mentally ill prisoner in psychatric hospital Death of a woman within 7 years of marriage Exhumation Rape of a woman I police custody In any case, Magistrate can conduct an inquest in addition to police inquest (CrPC 176) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 7", "cop": 3, "opa": "Sec 174 CrPC", "opb": "Sec 175CrPC", "opc": "Sec 176CrPC", "opd": "Sec 177CrPC", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c6da4236-d569-48be-8f67-13a10774ce8c", "choice_type": "single"} {"question": "Masseter is supplied by nerve", "exp": "The mandibular nerve The mandibular nerve leaves the inferior margin of the trigeminal ganglion & leaves the skull through the foramen ovale. The motor root of the trigeminal nerve also passes through the foramen ovale & unites with the sensory component of the mandibular nerve (V3) outside the skull. Thus, the V3 is the only division of the trigeminal nerve that contains a motor component. Outside the Skull- The motor fiber innervates the four muscles of mastication. | Temporalis, masseter, medial pterygoids, lateral pterygoids As well as - Tensor tympani muscle, tensor veli palatini muscle, the anterior belly of digastric & the mylohyoid muscle. Sensory pa of V3:- receives sensory fibers from. -The skin of lower face, cheek, lower lip, anterior pa of external ear, pa of external acoustic meatus & temporal region etc.", "cop": 1, "opa": "Mandibular", "opb": "Facial", "opc": "Glossopharyngeal", "opd": "Hypoglossal", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "54c3e8fb-deaa-4cde-9eed-3f3d63e6a967", "choice_type": "single"} {"question": "Superficial perineal muscles include", "exp": "The superficial perineal pouch is a compament of perineum.Its inferior border is superficial perineal fascia.Superior border is perineal membrane. Superficial perineal pouch consist of :Ischiocavernous muscle , Bulbospongiosus , Superficial transverse perineal muscle etc Ref - BDC 6e Vol2 pg 350", "cop": 3, "opa": "Iliococcygeus", "opb": "Ischiococcygeus", "opc": "Bulbospongiosus", "opd": "Levator ani", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "933bc71d-4165-4380-a685-881cffb38e35", "choice_type": "single"} {"question": "The neck of pancreas is related on its posterior surface to", "exp": "Neck of pancreas is located between the head and the body of the pancreas. It overlies the superior mesenteric vessels which form a groove in its posterior aspect. Ref - BDC 6e vol2 pg 298-300", "cop": 2, "opa": "Gastroduodenal aery", "opb": "Superior mesenteric vein", "opc": "Inferior vena cava", "opd": "Bile duct", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "88fdea41-221e-4549-91c2-8fedbcfd0b1c", "choice_type": "single"} {"question": "Brunner glands are seen in", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:272 The wall of the small intestine is made up of the four layers: mucous,submucous,muscularis and serous.the serous and muscular layers correspond exactly to the general structure of the alimentary canal.the sub mucosa is also typical except in the duodenum,where it contains the glands of brunner", "cop": 2, "opa": "Stomach", "opb": "Duodenum", "opc": "Ileum", "opd": "Appendix", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a25fb7b9-5083-4469-a3a8-4ac9f403a24b", "choice_type": "single"} {"question": "A 45 Yr old woman presents with a hard and mobile lump in the breast. Next investigation is", "exp": "First investigation : Mammography First investigation for tissue sampling : FNAC Best and diagnostic investigation : Biopsy Investigations in CA Breast Mammography - Initial investigation for symptomatic breast in women>35 years and for screening. Investigation of choice for microcalcification Ultrasound- Initial investigation for palpable lesions in women < 35 years. Not useful in screening MRI- Indicated in scarred breast, implants and borderline lesions for breast conservation. Investigation of choice for implant related complication. Gold standard for imaging breast in females with implants. PET scan- Investigation of choice for detecting recurrences in scarred breast. Useful multifocal disease and in helping detect axillary movement Ref:Sabiston 20th edition Pg no : 826- 827", "cop": 3, "opa": "FNAC", "opb": "USG", "opc": "Mammography", "opd": "Excision biopsy", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "5ff569f5-e949-4e21-b2db-1540a33a2c04", "choice_type": "single"} {"question": "Birbeck granules are present in", "exp": "Ref Robbins 9/e p662 Birbeck granules, also known as Birbeck bodies, are rod shaped or \"tennis-racket\" cytoplasmic organelles with a central linear density and a striated appearance. First described in 1961 (where they were simply termed \"characteristic granules\"), they are solely found in Langerhans cells.", "cop": 2, "opa": "Merkel cells", "opb": "Langerhans cells", "opc": "Langhans cells", "opd": "Melanocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1c30645f-b97c-4f13-bccb-2b66c6dc0d97", "choice_type": "single"} {"question": "Deltoid ligament has no attachment to", "exp": "Deltoid ligament has attachments to Tibia, Navicular, Calcaneum, Talus.", "cop": 3, "opa": "Talus", "opb": "Navicular", "opc": "Calcaneus", "opd": "Cuneiform", "subject_name": "Anatomy", "topic_name": null, "id": "4bcd188c-82be-41a9-bb00-76a06c4a959a", "choice_type": "single"} {"question": "Fever occurs due to", "exp": "ref Robbins 8/e p61,66,9/e p83,90 IL-1 is intensely produced by tissue macrophages, monocytes, fibroblasts, and dendritic cells, but is also expressed by B lymphocytes, NK cells, microglia, and epithelial cells. They form an impoant pa of the inflammatory response of the body against infection. These cytokines increase the expression of adhesion factors on endothelial cells to enable transmigration (also called diapedesis) of immunocompetent cells, such as phagocytes, lymphocytes and others, to sites of infection. They also affect the activity of the hypothalamus, the thermoregulatory center, which leads to a rise in body temperature (fever) . That is why IL-1 is called an endogenous pyrogen. Besides fever, IL-1 also causes hyperalgesia (increased pain sensitivity), vasodilation and hypotension", "cop": 1, "opa": "IL1", "opb": "Endorphin", "opc": "Enkephalin", "opd": "Histamine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "39376ed2-69c9-47bf-be37-f07b09f3e61b", "choice_type": "single"} {"question": "Root value of supinator jerk is", "exp": "Ref - Researchgate.net", "cop": 3, "opa": "C3 C4", "opb": "C4 C5", "opc": "C5 C6", "opd": "C8 T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "0a7c216c-92ec-4952-b3af-1bde430d332b", "choice_type": "single"} {"question": "Nerve supply of rhomboides major", "exp": "Dorsal scapular nerve arising from the nerve root C5 supplies both rhomboides major and minor. Rhomboides major retract the scapula. B D Chaurasia 7th edition Page no : 65", "cop": 3, "opa": "Spinal accessory nerve, cranial pa", "opb": "Spinal accessory nerve, spinal pa", "opc": "Dorsal scapular nerve", "opd": "Thoracodorsal nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "df40a4f8-8b36-4f7d-a955-7c060f1227c3", "choice_type": "single"} {"question": "Immunity against cancer cells", "exp": "Ref Robbins 8/EP 188;9/e p192 NK cells kill virus- infected cells and produce the macrophage-activating cyto- kine IFN-g. If the microbes enter the blood, many plasma proteins, including the proteins of the complement system, recognize the microbes and are activated, and their products kill microbes and coat (opsonize) the microbes for phagocytosis. In addition to combating infections, innate immune responses stimulate subsequent adaptive immu- nity, providing signals that are essential for initiating the responses of antigen-specific T and B lymphocytes.", "cop": 3, "opa": "Basophil", "opb": "Eosinophils", "opc": "NK cells", "opd": "Neutrophil", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "67c8d43f-4b74-426c-9de0-7363a4d97139", "choice_type": "single"} {"question": "Reticulocytosis is not a feature of", "exp": "Ref Harrison 19 th ed pg 630 Progressive CKD is usually associated with a moderate to severe hypoproliferative anemia; the level of the anemia corre- lates with the stage of CKD. Red cells are typically normocytic and normochromic, and reticulocytes are decreased.", "cop": 4, "opa": "Paroxysmal nocturnal hemoglobinuria", "opb": "Following acute bleeding", "opc": "Hereditary spherocytosis", "opd": "Anemia in CRF", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "92da265b-50b6-43db-82b0-7990d582fac9", "choice_type": "single"} {"question": "The Gustatory nucleus is a pa of", "exp": "The rostral pa of the solitary nucleus is sometimes referred to as the gustatory nucleus. The solitary nucleus conveys information about taste and visceral sensations", "cop": 1, "opa": "Solitary nucleus", "opb": "Hypoglossal nucleus", "opc": "Nucleus ambiguous", "opd": "Dorsal motor nucleus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "2c4d93d3-cb13-4e72-ae9e-cfebe1218739", "choice_type": "single"} {"question": "The trigeminal ganglion is", "exp": null, "cop": 3, "opa": "A motor and sensory ganglion of trigeminal nerve", "opb": "Made up of unipolar and bipolar cells", "opc": "Homologous with the dorsal root ganglion", "opd": "Receives the motor root at its posterior concavity", "subject_name": "Anatomy", "topic_name": null, "id": "c4d8c032-3e9a-411b-89a0-539fd93e839a", "choice_type": "single"} {"question": "Ligament supporting the head of talus is", "exp": "Ans. d (Plantar calcaneonavicular ligament ). (Ref. BDC, Vol. II, 3rd ed., 132, 135, 136)# The head of talus rests directly on the upper surface of the Plantar calcaneonavicular ligament (Spring ligament), which is covered by fibrocartilage.# The plantar calcanonavicular ligament, as the name sugests, runs from the sustentaculum tali of the calcaneum to the navicular bone on its inferior aspect. The upper surface of the ligament is covered by fibrocartilage and strongly supports the head of the talus from below. It also acts like a tie beam to support the medial longitudinal arch.# Most commonly the lateral collateral ligament is sprained, mostly so anterior talo-fibular component.2Also remember:Talar neck fractures are the commonest injury and are usually high energy (historically termed 'aviator's astragalus'). A significant complication is avascular necrosis of the talus. The goal of treatment is anatomical reduction and stable fixation, which helps reduce the risk of osteonecrosis. Hawkins' sign can be seen approximately 6-8 weeks after injury on plain radiographs. This appears as subchondral lucency of the talar dome, which signifies bony reabsorption, i.e. a viable bone.", "cop": 4, "opa": "Short plantar ligament", "opb": "Long plantar ligament", "opc": "Medial ligament (Deltoid ligament)", "opd": "Plantar calcaneonavicular ligament (Spring ligament)", "subject_name": "Anatomy", "topic_name": "Osteology of Lower Extremity", "id": "1157ebbb-a8de-4b16-ae1b-b8e08d6ed038", "choice_type": "single"} {"question": "Level III neck nodes are", "exp": null, "cop": 4, "opa": "In the sub-mental triangle", "opb": "In the posterior triangle", "opc": "In the midline from hyoid to suprasternal notch", "opd": "around the middle 1/3rd of internal jugular vein", "subject_name": "Anatomy", "topic_name": null, "id": "63528280-d85b-4534-b479-d0b82a759723", "choice_type": "single"} {"question": "Regarding oncogenesis", "exp": "Topoisomerase2 causes break in strands ; and option C and D is also answer ref Harrison 16/e p453; 454; Robbins 7/e Cell Cycle Inhibitor Proteins Topoisomerases can fix these topological problems and are separated into two types depending on the number of strands cut in one round of action: Both these classes of enzyme utilize a conserved tyrosine. However these enzymes are structurally and mechanistically different. For a video of this process click here. A type I topoisomerase cuts one strand of a DNA double helix, relaxation occurs, and then the cut strand is re-ligated. Cutting one strand allows the pa of the molecule on one side of the cut to rotate around the uncut strand, thereby reducing stress from too much or too little twist in the helix. Such stress is introduced when the DNA strand is \"supercoiled\" or uncoiled to or from higher orders of coiling. A type II topoisomerase cuts both strands of one DNA double helix, passes another unbroken DNA helix through it, and then re-ligates the cut strands. Type II topoisomerases utilize ATP hydrolysis and are subdivided into two subclasses which possess similar structure and mechanisms: Type IIA topoisomerases which include eukaryotic and eukaryal viral Topoisomerase IIa and Topoisomerase IIb, bacterial gyrase, and topoisomerase IV. Type IIB topoisomerases, which include Topoisomerase VI found in archaea", "cop": 1, "opa": "Topoisomerase2 causes break in strands", "opb": "P53 is the most common oncogene mutation causing malignancy in humans", "opc": "At G2_M phase there is loss of inhibitors controlling cell cycle", "opd": "Decrease in telomerase activity causes anti tumor effects", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fbc5e38d-be2f-49bb-8191-33985c8f8403", "choice_type": "single"} {"question": "'Crumbled egg appearance' in liver is seen in", "exp": "Crumbled egg appearance in liver is seen in hyadatid disease", "cop": 3, "opa": "Hepatic adenoma", "opb": "Chronic amoebic liver disease", "opc": "Hydatid liver disease", "opd": "Hemangioma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "32f37281-6446-44ac-a201-bac4168c8de1", "choice_type": "single"} {"question": "Anterior end of the spleen is held up by", "exp": "The posterior end is rounded and is directed upward and backward; it rests on the upper pole of the left kidney. The spleen's 3 borders are the superior, inferior, and intermediate. The superior border of the spleen is notched by the anterior end. The inferior border is rounded. Ref - researchgate.net", "cop": 2, "opa": "Leinorenal ligament", "opb": "Phrenicocolic ligament", "opc": "Gastrosplenic ligament", "opd": "Gastrocolic ligament", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fd977189-28f0-4e3e-bdaa-b76d4a8df01a", "choice_type": "single"} {"question": "ulimia nervosa is assosiated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 1, "opa": "impulsive behaviour", "opb": "obesity", "opc": "metabolic syndrome", "opd": "amnorrhera", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "d4cd674c-3a81-41e3-9103-38105e6ea463", "choice_type": "single"} {"question": "Most posterior structure seen in root of lung is", "exp": "Most posterior structure in the root of the lung is bronchus B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME1 SIXTH EDITION Page no-237", "cop": 1, "opa": "Bronchus", "opb": "Superior pulmonary vein", "opc": "Inferior pulmonary vein", "opd": "Pulmonary aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "3e269f6f-3504-477d-98fd-056a1f650354", "choice_type": "single"} {"question": "Structures passing through the aortic hiatus of diaphragm area) Aortab) Azygos veinc) Hemiazygos veind) Thoracic ducte) Sympathetic trunk", "exp": "Aortic opening\n-        Level- T12\n-        At osseoaponeurosis between right and left crus\n-        Structures transmitted\n\n   Aorta\n   Thoracic duct\n   Azygos vein", "cop": 2, "opa": "acd", "opb": "abd", "opc": "abc", "opd": "ab", "subject_name": "Anatomy", "topic_name": null, "id": "3a8db914-4b0d-4d4f-a97d-bfee10595462", "choice_type": "single"} {"question": "DEEP PETROSAL nerve arises from", "exp": "The deep petrosal nerve, sympathetic in nature is a branch of the sympathetic plexus around the internal carotid aery. It contains postganglionic fibres from the superior cervical sympathetic ganglion. The nerve joins the greater petrosal nerve to form the nerve of the pterygoid canal. The sympathetic fibres in it are distributed through the branches of the pterygopalatine ganglion. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Facial nerve", "opb": "Glossopharyngeal nerve", "opc": "Plexus around internal carotid aery", "opd": "Mandibullar nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "96124c59-2e4e-4feb-8343-5c8dde9725e5", "choice_type": "single"} {"question": "The appropriate media culture for a gram negative coccobacilli arranged in a school of fish , that causes STD with genital ulcers is", "exp": "Chocolate agar enriched with 1%isovitalex is used to grow H.ducreyi.", "cop": 3, "opa": "Thayer Main media", "opb": "Blood agar with X and V factors", "opc": "Chocolate agar with isovitale X", "opd": "Tellurite blood agar", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "3b28bd2e-1776-489b-8986-c73c47a595d5", "choice_type": "single"} {"question": "The most commonest cause for chronic cor pulmonale is", "exp": "Ref Harrison 19 th ed pg 1505 Once patients with chronic pulmonary or pulmonary vascular disease develop cor pulmonale, the prognosis worsens. Although chronic obstructive pulmonary disease (COPD) and chronic bronchitis are responsible for approximately 50% of the cases of cor pulmonale .", "cop": 2, "opa": "Recurrent pulmonary embolization", "opb": "COPD", "opc": "cystic fibrosis", "opd": "Bronchial asthma", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "d06c306b-6d84-4c10-bc93-0bd3a55ae0c6", "choice_type": "single"} {"question": "NOT a content of Deep perineal pouch among the following is", "exp": "Membranous urethra is a content of Deep perineal pouch, not prostatic urethra.", "cop": 2, "opa": "External urethral sphincter", "opb": "Prostatic urethra", "opc": "Bulbourethral gland", "opd": "Deep transverse perineal muscle", "subject_name": "Anatomy", "topic_name": null, "id": "aa75deef-d813-407e-9fc8-782e408a7cd3", "choice_type": "single"} {"question": "On bimanual palpation, the feeling of absent uterus is termed as", "exp": "Hegar's sign Softeningof the lower uterine segment can be elicited between second and fifth month of pregnancy. In a bimanual palpation with one hand placed on the abdomen and two fingers in the vagina the lower uterine segment is not felt and fingers of hands will touch together as if no uterus is between. This test is not recommended now for fear of disturbance of pregnancy. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 330", "cop": 3, "opa": "Palmer's sign", "opb": "Chadwick's sign", "opc": "Hegar's sign", "opd": "Goodell's sign", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "afe4f35b-dbdd-433f-8aa8-1ef5f39bd2ac", "choice_type": "single"} {"question": "Deiters cells are present in", "exp": "Deiters&; cells, also known as phalangeal cells are found within the organ of Coi.The organ of Coi is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic duct and is composed of mechanosensory cells, known as hair cells. Strategically positioned on the basilar membrane of the organ of Coi are three rows of outer hair cells (OHCs) and one row of inner hair cells (IHCs). Separating these hair cells are suppoing cells called Deiters cellsReference: Krishna Garg Histology; 5th edition; Page no: 258", "cop": 1, "opa": "Organ of Coi", "opb": "Scala media", "opc": "Pharynx", "opd": "Larynx", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "75f9de05-ed11-4e9d-9ad9-3a4c02e20929", "choice_type": "single"} {"question": "Muscle causing flexion of hip", "exp": "Hip flexion is brought about by the action of iliopsoas aided by the rectus femoris ,saorius, and pectineus.Tensor fasciae latae(TFL) aids gluteus minimus and medius in abduction and medial rotation.Gluteus maximus helps in extension and lateral rotation.Biceps femoris helps inflexionReference : Clinical Anatomy for students, a problem solving approach, Neeta v Kulkarni, 2nd edition, page no.932", "cop": 2, "opa": "Biceps femoris", "opb": "Psoas major", "opc": "Gluteus maximus", "opd": "Tensor fasciae latae", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d8b77e70-4303-4b86-a9c4-274c3fae20a2", "choice_type": "single"} {"question": "Macular sparing is seen in affection of", "exp": "MACULA HAS GOT DUAL SUPPLY-BOTH MCA AND PCA", "cop": 3, "opa": "Optic nerve", "opb": "Optic chiasma", "opc": "Occipital lobe", "opd": "Parietal lobe", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3300be05-a8a0-4f6e-b544-9d5ce57c4e91", "choice_type": "single"} {"question": "Sacrotuberous ligament is not pierced by", "exp": "Sacrotuberous ligament is pierced by\n\nCoccygeal branch of Inferior gluteal nerve\nPerforating cutaneous nerves\nFilaments of Coccygeal plexus", "cop": 3, "opa": "Coccygeal branch of Inferior gluteal nerve", "opb": "Perforating cutaneous nerves", "opc": "Posterior cutaneous nerve of thigh", "opd": "Filaments of Coccygeal plexus", "subject_name": "Anatomy", "topic_name": null, "id": "017b7329-89d5-4bf7-a501-63fc4e13f8ae", "choice_type": "single"} {"question": "Charcot's triad", "exp": "Charcot's triad is seen in cholangitis It is characterized by Abdominal pain Jaundice Fever Reynold's pentad Charcot's triad Altered mental status. Shock (hypotension) Ref: Sabiston 20th edition Pgno :1507", "cop": 1, "opa": "Fever, abdominal pain, jaundice", "opb": "Fever, vomiting, jaundice", "opc": "Fever, jaundice, abdominal distension", "opd": "Fever, diarrhoea, jaundice", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5f9d1dc2-f00d-4a53-a0f4-d3c6c49e3254", "choice_type": "single"} {"question": "The Vein of Galen drains into", "exp": "Ans. b (Straight sinus). (Ref. BD Chaurasia, Anatomy, 3rd ed., Vol III 303)Great Cerebral Vein Of Galen# Single median vein formed by union of two internal cerebral veins.# Terminates into straight sinus.# Its tributaries include the basilic vein, veins from pineal body, colliculi, cerebellum and adjoining occipital lobes.# Vein of Galen malformation is one of the most common cause of congestive cardiac failure in neonates.# The dural venous sinuses receive cerebral veins from the brain and drain the venous blood mainly into the IJV.Dural venous sinusesSuperior sagittal sinus# It drains into the concluence of the sinuses (Torcular).Inferior sagittal sinus# It is located in the midsagittal plane, near the inferior margin of the falx cerebri.# It terminates by joining with the great cerebral vein of Galen to form the straight sinus at the junction of the falx cerebri and tentorium cerebelli.Straight sinus# It is formed by the union of the inferior sagittal sinus and the great cerebral vein.# It usually terminates by draining into the confluence of sinuses (or in transverse sinus).Occipital sinus# It is found in the attached border of the tentorium cerebelli.# It drains into the confluence of sinuses.Confluence of sinuses (torcular herophili)# It is formed by the union of the superior sagittal, straight, and occipital sinuses.# It drains into the two transverse sinuses.Transverse sinuses (Lateral sinuses)# It drains venous blood from the confluence of sinuses into the sigmoid sinuses.# Each sigmoid sinus joins with an inferior petrosal sinus to drain into the internal jugular vein below the jugular foramen.# Thrombosed in complicated chronic mastoiditis (DELTA SIGN on CT).", "cop": 2, "opa": "Sigmoid sinus", "opb": "Straight sinus", "opc": "Transverse sinus", "opd": "Basal vein", "subject_name": "Anatomy", "topic_name": "Meninges & Blood Vessels of the Brain", "id": "f717454b-eded-4b2e-9d41-4d4860ae5924", "choice_type": "single"} {"question": "Blood supply of ventral 2/3rd of interventricular septum of hea is", "exp": "The posterior interventricular aery, a branch of right coronary aery, supplies the posterior 1/3 of the interventricular septum. The remaining anterior 2/3 is supplied by the anterior interventricular aery which is a septal branch of the left anterior descending aery, which is a branch of left coronary aery . B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION Page-265", "cop": 2, "opa": "Right coronary aery", "opb": "Left coronary aery", "opc": "Posterior interventricular aery", "opd": "Marginal aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d6da4e7e-013d-4508-a1bc-75230e1169f2", "choice_type": "single"} {"question": "Child rolls over by", "exp": "Once the assymetric tonic reflex disappears, baby learns to roll over from prone to supine and vice versa. Between 4 to 6 months, baby learns to roll over from back to side and then from back to stomach. Ref: Ghai, 9 th edition, page- 42.", "cop": 2, "opa": "3 months", "opb": "6 months", "opc": "7 months", "opd": "8 months", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bf5af90b-3e18-49bd-9a89-5e06c5115a84", "choice_type": "single"} {"question": "Lymph from glans penis drains into", "exp": "All the lymphatic vessels of the penis passes to the superficial inguinal nodes by accompanying the external pudendal blood vessel. The lymphatic vessels of glands penis enter to the deep inguinal nodes and external iliac nodes. Ref - BDC 6e vol2 pg219", "cop": 2, "opa": "Superficial inguinal nodes", "opb": "Deep inguinal lymph nodes", "opc": "Obturator nodes", "opd": "Internal iliac nodes", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "4f357911-20ba-43bc-97f1-27e874931cde", "choice_type": "single"} {"question": "Most common cause of peritonitis in adult male is", "exp": "MC cause of peritonitis in adult male: Peptic ulcer perforation * The most common cause is a perforation of the abdominal viscus-most commonly, a perforated ulcer, may occur as a result of perforation of any pa of the bowel; other causes include a benign ulcer, a tumor, or trauma.* MC cause of peritonitis in adult male: Peptic ulcer perforation", "cop": 4, "opa": "Duodenal ulcer perforation", "opb": "Abdominal tuberculosis", "opc": "Enteric perforation", "opd": "Perforated appendix", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e8c568f9-a54e-42b5-8673-58b85c97c95d", "choice_type": "single"} {"question": "Modiolus (apex) is directed", "exp": "B i.e. Anterolateral - inferior", "cop": 2, "opa": "Anterolateral - superior", "opb": "Anterolateral - inferior", "opc": "Posteromedial superior", "opd": "Poster() medial - inferior", "subject_name": "Anatomy", "topic_name": null, "id": "db22405f-3f24-429c-988b-c2fa3bba39aa", "choice_type": "single"} {"question": "Collagen found in hyaline cailage is", "exp": "Collagen present in cailage are chemically distinct from those in most other tissues.They are described as type 2 collagen Inderbir Singh&;s textbook of human Histology Seventh edition Pg no 82", "cop": 2, "opa": "Type I", "opb": "Type II", "opc": "Type IV", "opd": "Type V", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f84822b1-ddbb-4b46-9074-c924e5278583", "choice_type": "single"} {"question": "Arrange the contents of cubital fossa medial to lateral", "exp": "Cubital fossa is a triangular hollow situated on the front of the elbow. Contents (medial to lateral)- M-Median nerve B-Brachial aery and it's branches B-Biceps brachi tendon S- Superficial branch of radial nerve* Lateral boundary is contributed by brachioradialis muscle, medially present is pronator teres and base is formed by an imaginary line connecting the two epicondyles.", "cop": 3, "opa": "Median Nerve -Biceps tendon - Brachial aery- Radial nerve", "opb": "Biceps tendon - Median Nerve - Brachial aery- Radial nerve", "opc": "Median Nerve - Brachial aery - Biceps tendon - Radial nerve", "opd": "Median Nerve - Radial nerve - Biceps tendon - Brachial aery", "subject_name": "Anatomy", "topic_name": "Muscles of arm and forearm region & Cubital fossa", "id": "121d2670-f3fa-40c0-9451-18d324f8bb3c", "choice_type": "single"} {"question": "Caspases are involved in.", "exp": "Caspes are present in normal cells as inactive proenzymes and when they are activated they cleave proteins and induce Apoptosis. These are cysteine professes.", "cop": 2, "opa": "A. Necrosis", "opb": "B. Apoptosis", "opc": "C. Atherosclerosis", "opd": "D. Inflammation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1d472bc4-5d2a-426e-ad89-dd7e323d561c", "choice_type": "single"} {"question": "DeQuervains thyroiditis is also known as", "exp": "Refer Robbins page no DeQuervains thyroiditis is also referred to as Granulomatous thyroiditis", "cop": 1, "opa": "Granulomatous thyroiditis", "opb": "Struma lymphomatosa", "opc": "Acute thyroiditis", "opd": "Hashimotos thyroiditis", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "05eb9f3e-301a-4e61-927e-c7f8bd11cacd", "choice_type": "single"} {"question": "The cytogenetics of the Chromophillic renal cell carcinoma is characterized by", "exp": "Chromophillic carcinoma is the other name of papillary renal cell carcinoma because 80% of Chromophillic cancers show tubopapillary architecture. As discussed, papillary cancer is associated with trisomy 7,16,17", "cop": 3, "opa": "Mutant VHL gene", "opb": "Loss 3p", "opc": "Trisomy 7/17", "opd": "Loss of 5q3", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "01d44a9f-11f3-4f3d-ba65-e6cda2552eab", "choice_type": "single"} {"question": "Mastoid fontanelle after ossification exists in adults as ,", "exp": "The asterion is the point where the parietomastoid, occipitomastoid and lambdoid sutures meet. In infants the asterion is the site of the posterolateral or mastoid fontanelle,which closes at the end of the first year.", "cop": 2, "opa": "Lambda", "opb": "Asterion", "opc": "Bregma", "opd": "Pterion", "subject_name": "Anatomy", "topic_name": null, "id": "4bf79ba8-9ef8-4df8-9808-a63f0e92bc62", "choice_type": "single"} {"question": "Epithelium present in thin segment of Loop of Henle is", "exp": "The epithelium of the Thick segment is simple cuboidal epithelium. The epithelium of the Thin segment is simple squamous.Reference: Krishna Garg Histology; 5th edition; Page no: 180", "cop": 4, "opa": "Simple Cuboidal Epithelium", "opb": "Simple Columnar Epithelium", "opc": "Stratified Columnar Epithelium", "opd": "Simple Squamous Epithelium", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "f31f962c-cb46-4156-a781-d91a674252aa", "choice_type": "single"} {"question": "The forward displacement of tibia on the femur is prevented by", "exp": "Anterior cruciate ligament prevents posterior displacement of the femur on the tibia and hyperextension of the knee joint. When the joint is flexed at a right angle, the tibia cannot be pulled anteriorly because it is held by the ACL.**watch the wordings carefullyReference: Chaurasia; 6th edition", "cop": 1, "opa": "Anterior cruciate ligament", "opb": "Posterior cruciate ligament", "opc": "Medical collateral ligament", "opd": "Lateral collateral ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "4d276923-cb98-4d38-b623-88ddd7ab9559", "choice_type": "single"} {"question": "Nerve supply of adductors of thigh includes", "exp": "(B) Obturator nerve# Obturator Nerve:> Obturator nerve (L2 L3 L4) is the chief nerve of the medial (adductor) compartment of the thigh.> It is a branch of the lumbar plexus.> It enters the thigh by passing through the obturator canal.> Anterior division of obturator nerve supplies the following muscles: Pectineus, Adductor longus, Gracilis, Adductor brevis.> Posterior division of obturator nerve supplies following muscles: Obturator extemus, Adductor magnus, Adductor brevis.> Adductor magnus has double nerve supply. Its adductor part is supplied by the obturator nerve, while its hamstring part is supplied by the tibial part of the sciatic nerve.> Pectineus also has a double innervation; its anterior fibres are supplied by the femoral nerve and the posterior fibres by the obturator nerve> Obturator nerve also give branches to the hip and the knee joint so a lesion of the nerve may cause pain in the hip & knee joint.", "cop": 2, "opa": "Femoral nerve", "opb": "Obturator nerve", "opc": "Inferior gluteal nerve", "opd": "Superior gluteal nerve", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "bf69d8b2-a2af-4e8d-a59a-e916828fa4f2", "choice_type": "single"} {"question": "The ureter is lined by .................ephithelium", "exp": "Ureters - Ureters are muscular tubes that conduct urine from renal pelvis to the urinary bladder. The wall of the ureter has three layers: An inner lining of mucous membrane , A middle layer of smooth muscle, An outer fibrous coat: adventitia. Mucous Membrane -The mucous membrane has a lining of transitional epithelium that is 4 to 5 cells thick and an underlying connective tissue, lamina propria. The mucosa shows a number of longitudinal folds that give the lumen a star-shaped appearance in transverse section. The folds disappear when the ureter is distended. REF: Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no.,317.", "cop": 4, "opa": "Stratified squamous", "opb": "Cuboidal", "opc": "Ciliated columnar", "opd": "Transitional", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e929c9af-5ec2-4d2c-becf-7a2c50c413d8", "choice_type": "single"} {"question": "External acoustic meatus is derived from", "exp": "(Dorsal part of the 1st ectodermal cleft) (357-IBS 8th) (317-I.B.Singh 8th)External acoustic meatus is derived from the dorsal part of the first ectodermal cleft. However, its deeper part is formed by proliferation of its lining epithelium.FATE OF ENDODERMAL POUCHESA. First pouch(a) Its ventral part is obliterated by formation of the tongue(b) Its dorsal part receives a contribution from the dorsal part of the second pouch, and these two together form a diverticulum that grows towards the region of the developing ear. This diverticulum that grows towards the region of the developing ear. This diverticulum is called the trubotympanic recess. The proximal part of this recess gives rise to the auditory (pharyngotympanic) tube, and the distal part to the, middle ear cavity including the tympanic antrumB. Second Pouch(a) The epithelial of the ventral part of this pouch contributes to the formation of the tonsil(b) The dorsal part takes part in the formation of the tubotympanic recessC. Third Pouch- give rise to inferior parathyroid gland & ThymusD. Fourth Pouch- gives origin to the superior parathyroid glands and may contribute to the Thyroid glandE. Fifth or Ultimobranchial pouch- give rise to ultimobranchial body (some species) & caudal pharyngeal complex", "cop": 1, "opa": "Dorsal part of the first ectodermal cleft", "opb": "Ventral part of the first ectodermal cleft", "opc": "Dorsal part of the 2nd ectodermal cleft", "opd": "Ventral part of the 2nd ectodermal cleft", "subject_name": "Anatomy", "topic_name": "Embryology", "id": "55ff05e4-a2c1-440d-865c-49f242936e31", "choice_type": "single"} {"question": "Middle deft upper lip due to failure of fusion b/w", "exp": "Defect\nCaused by\n\n\nCleft upper lip\nFailure of fusion between maxillary process and medial naral process\n\n\nMedial deft upper lip\nFailure of fusion between maxillay process and medial and lateral naral process\n\n\nOblique facial deft\nFailure of fusion between maxillary process and medial lateral naral process\n\n\nLower lip deft\nFailure of fusion of two mandibular process", "cop": 2, "opa": "Maxillary process", "opb": "Medial naral process", "opc": "Medial and lateral naral process", "opd": "Medial naral process and maxillary process", "subject_name": "Anatomy", "topic_name": null, "id": "93c49d73-aacb-49df-97ba-5109efd6af13", "choice_type": "single"} {"question": "Caplan's syndrome is pneumoconiosis with", "exp": "Pulmonary manifestations of RA include pleurisy with or without effusion, ILD in up to 20% of cases, necrobiotic nodules (nonpneumoconiotic intrapulmonary rheumatoid nodules) with or without cavities, Caplan syndrome (rheumatoid pneumoconiosis), pulmonary hypeension secondary to rheumatoid pulmonary vasculitis, organized pneumonia, and upper airway obstruction due to cricoarytenoid ahritis. Ref Harrison 19th edition pg 1713", "cop": 3, "opa": "Lymphadenopathy", "opb": "Congestive cardiac failure", "opc": "Rheumatoid ahritis", "opd": "HIV", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "6e876510-1198-4b39-8d43-87eceb3e8f8d", "choice_type": "single"} {"question": "Most common site of cholangiocarcinoma", "exp": "Cholangiocarcinoma Tumors arising from bile duct epithelium. Most common type is adenocarcinoma Differentiated by anatomic site of origin: Intrahepatic (10%), Hilar (65%), and distal (25%) MC gene mutation is K-ras >p16(KRAP-16) Ref: Sabiston 20th edition Pgno :1514-1518", "cop": 2, "opa": "Distal biliary tract", "opb": "Hilum", "opc": "Intrahepatic duct", "opd": "Multifocal", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d53ab076-3a25-446b-919f-61eabb720dc6", "choice_type": "single"} {"question": "Hand and foot syndrome is an adverse effect of", "exp": "Ref-Katzung 11/e p947 Capecitabine and 5-FU can cause hand and foot syndrome", "cop": 1, "opa": "5-Flurouracil", "opb": "Bleomycin", "opc": "Etoposide", "opd": "Actinomycin-D", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "0743454c-e310-4414-84f6-a6c1a632db7f", "choice_type": "single"} {"question": "A strong propensity for vacuolar invasion is seen in", "exp": "Ref Robbins 7/e p925; 9/e p274 Renal and hepatocellular carcinomas hav high tendency invasion of vascular channels MORPHOLOGY HCC may appear grossly as (1) a unifocal, usually massive tumor; (2) a multifocal tumor made of nodules of variable size; or (3) a diffusely infiltrative cancer, permeating widely and sometimes involving the entire liver, blending imperceptibly into the cirrhotic background. Paicularly in the latter two patterns, it may be difficult to radiologically distinguish regenerative cirrhotic nodules from neoplasms of similar size. Discrete tumor masses usually are yellow- white, punctuated sometimes by bile staining and areas of hemorrhage or necrosis. HCC has a strong propensity for vascular invasion. Extensive intrahepatic metastases are characteristic, and occasionally snakelike masses of tumor invade the poal vein (with occlusion of the poal circula- tion) or inferior vena cava, extending even into the right side of the hea. On histologic examination, HCCs range from well- differentiated lesions that reproduce hepatocytes arranged in cords, trabeculae or glandular patterns (Fig. 15-34), to poorly differentiated lesions, often composed of large, multinucleate anaplastic giant cells. In the better-differentiated vari- ants, globules of bile may be found within the cyto- plasm of cells and in pseudocanaliculi between cells. Acidophilic hyaline inclusions within the cytoplasm may be present, resembling Mallory bodies. There is little stroma in most hepatocellular carcinomas, explaining their soft consistency. A distinctive clinicopathologic variant of HCC is the fibrolamellar carcinoma. It occurs in young male and female adults (20 to 40 years of age) with equal incidence and has no association with cirrhosis or other risk factors. It usually consists of a single tumor with fibrous bands coursing through it, superficially resembling focal nodular hyperplasia. The fibrolamellar variant has a better prognosis than that of the other, more common variants.", "cop": 2, "opa": "Prostatic carcinoma", "opb": "Hepatocellular carcinoma", "opc": "Bronchogenic carcinoma", "opd": "Gastric carcinoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ab2b7c0c-9ecd-4613-b649-0f4c3a874c3f", "choice_type": "single"} {"question": "Constrictions in Esophagus by aoa is present at distance of from incisor", "exp": "Construction of oesophagus at the following levels 15 cm-crossed by cricopharyngeus 22.5 cm-crossed by aoa 27.5 cm-crossed by left bronchus 37.5 cm-pierces the diaphragm All from incisor teeth BD CHAURASIA'S HUMAN ANATOMY VOL.1,PAGE NO 282", "cop": 2, "opa": "15 cm", "opb": "25cm", "opc": "30 cm", "opd": "40 cm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "c15e6597-0d68-41ca-9b85-8403f532b76c", "choice_type": "single"} {"question": "Scarpa's fascia gets attached to", "exp": "Scarpa's fascia is the deep membranous layer of superficial fascia of anterior abdominal wall. It crosses the inguinal ligament and gets attached to the fascia lata of thigh along Holden's line below and parallel to inguinal ligament. fig:-layers of abdominal wall", "cop": 2, "opa": "Inguinal ligament", "opb": "Fascia lata of thigh", "opc": "Conjoint tendon", "opd": "Pubic crest", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "74080a0a-1566-4d9b-ae9b-4bc89d298850", "choice_type": "single"} {"question": "First lumbrical canal communicates with", "exp": "Thenar space communicates with first web space through first lumbrical canal.The midpalmar space communicates with medial 3 web spaces through medial 3 lumbrical canals.Reference: Textbook of anatomy upper limb and thorax, Vishram Singh, second edition, page no 154, 153", "cop": 3, "opa": "Adductor space", "opb": "Midpalmar space", "opc": "Thenar space", "opd": "Hypothenar space", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "2698d209-c2a8-4247-a1cf-33b0ba5c676c", "choice_type": "single"} {"question": "Unilateral palsy of external laryngeal nerve leads to", "exp": null, "cop": 2, "opa": "Aphonia", "opb": "Hoarseness of voice", "opc": "Paralysis", "opd": "Loss of timber of voice", "subject_name": "Anatomy", "topic_name": null, "id": "09333bae-d5de-4243-84dd-4297ade7bd85", "choice_type": "single"} {"question": "Farmers lung is caused due to exposure to", "exp": "Farmer's Lung This condition results from exposure to moldy hay containing spores of thermophilic actinomycetes that produce a hypersensitivity pneumonitis. Ref Harrison 19th edition 1691", "cop": 2, "opa": "Bacillus subtilis", "opb": "Thermoactinomyces saccharri", "opc": "Aspergillus fumigates", "opd": "Penicillium nalgiovense", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "af6c3fec-8da1-471e-bb61-b2e59106508c", "choice_type": "single"} {"question": "Adductor canal lies beneath the", "exp": "ADDUCTOR CANAL:- Also known as Hunter's or subsaorial canal. It is an intermuscular space situated on the medial side of the middle one-third of the thigh. Extend -from apex of femoral triangle above to the tendinous opening in adductor Magnus below. Shape:- Triangular on cross section. Boundaries:--Anterolateral wall: vastus medialis.-Posteromedial wall/Floor:Adductor longus above and adductor Magnus below.-Medial wall/Roof: strong fibrous membrane joining Anterolateral and posteromedial walls. Roof overlapped by Saorius. Subsaorial plexus of nerves lies on the fibrous roof of the canal under saorius. Plexus is formed by branches from the medial cutaneous nerve of thigh, the saphenous nerve and the anterior division of the obturator nerve. It supplies skin over fascia lata and neighboring skin. Contents:-1. Femoral aery: enters the canal at the apex of the femoral triangle. Within the canal, it gives off muscular branches and descending genicular branch. It leaves the canal through opening in adductor Magnus to continue as popliteal aery.2. Femoral vein lies posterior to femoral aery( upperclassmen pa) and lateral to the aery ( lower pa).3. Saphenous nerve: cross the femoral aery anteriorly from lateral to medial side.4. Nerve to vastus medialis 5. Branches of two divisions of obturator nerve: Anterior division emerges at the lower border of adductor longus, gives branches to subsaorial plexus and ends by supplying femoral aery. Posterior division of the obturator nerve runs on anterior surface of adductor magus and ends by supplying knee joint. {Reference: BDC 6Epg no.56}", "cop": 3, "opa": "Adductor longus", "opb": "Adductor magnus", "opc": "Saorius", "opd": "Vastus medialis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7ec53067-a568-46a5-9b5b-83a8faf5b14e", "choice_type": "single"} {"question": "Meckel's diveiculum is a remnant of", "exp": "INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY-page no:195 Persistence of a pa of the vitellointestinal duct may give rise to the presence of a diveiculum attached to the terminal pa of the ileum.this is called Meckel's diveiculum or diveiculum ilei", "cop": 4, "opa": "Stenson's duct", "opb": "Wolffian duct", "opc": "Mullerin duct", "opd": "Vitellointestinal duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "792c2cc3-3201-48c5-ba05-e5bedbc191b3", "choice_type": "single"} {"question": "Barr body is found in the following phase of the cell cycle", "exp": "Inactivated X chromosomes seen in female somatic cells are called Barr-bodies which are present adjacent to the nuclear membrane. In humans with more than one X chromosome, the number of Barr bodies visible at interphase is always one fewer than the total number of X chromosomes.", "cop": 1, "opa": "Interphase", "opb": "Metaphase", "opc": "GI phase", "opd": "Telophase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f22c162a-4a4a-4eb5-9947-d43152fe14a5", "choice_type": "single"} {"question": "Trochlear nerve nucleus lies at the level of", "exp": "Trochlear nerve nucleus is located in anterior part of gray matter that surrounds cerebral aqueduct, at the level of inferior colliculus.", "cop": 2, "opa": "Inferior cerebellar peduncle", "opb": "Inferior colliculus", "opc": "Superior colliculus", "opd": "Superior cerebellar peduncle", "subject_name": "Anatomy", "topic_name": null, "id": "94156aab-6f84-4200-9ac9-05c6bca40145", "choice_type": "single"} {"question": "The Pectoralis major is classified as a (2018)", "exp": "Spiral or Twisted Fasciculi Spiral or twisted fibres are found in trapezius, pectoralis major, latissimus dorsi, supinator Ref:-BD chaurasia handbook of general anatomy , pg num:-91", "cop": 1, "opa": "A) Spiral muscle", "opb": "B) Cruciate muscle", "opc": "C) Fusiform fasiculus", "opd": "D) Bipennate muscle", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0f1c0b8e-c65f-4f30-a90e-670e6d8263af", "choice_type": "single"} {"question": "CPD in absence of gross pelvic abnormality can be diagnosed by", "exp": "Best method to rule out CPD is trial of labor Best investigation MRI", "cop": 2, "opa": "Ht of mother < 158 cms", "opb": "Trial of labor", "opc": "X ray pelvimetry", "opd": "Pelvic examination", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "6ce7c31b-5412-409d-8ca6-5fb707da39dd", "choice_type": "single"} {"question": "Most common histological type of renal cell carcinoma", "exp": "Refer Robbins 9/e p953 Clear cell carcinoma. This is the most common type, accounting for 70% to 80% of renal cell cancers. The tumors are made up of cells with clear or granular cytoplasm and are nonpapillary. They can be familial, but in most cases (95%) are sporadic. In 98% of these tumors, whether familial, sporadic, or associated with VHL syndrome, there is loss of sequences on the sho arm of chromosome 3. The deleted region harbors the VHL gene (3p25.3). A second nondeleted allele of the VHL gene shows somatic mutations or hypermethylation-induced inactivation in up to 80% of clear cell cancers, indicating that the VHL gene acts as a tumor suppressor gene in both sporadic and familial cancers (Chapter 7). The VHL gene encodes a protein that is pa of a ubiquitin ligase complex involved in targeting other proteins for degradation. Impoant among the targets of the VHL protein is the transcription factor hypoxia- inducible factor-1 (HIF-1). When VHL is inactive, HIF-1 levels remain high, even under normoxic conditions, causing inappropriate expression of a number of genes that are turned on by HIF. These include genes that promote angiogenesis, such as VEGF, and genes that stimulate cell growth, such as insulin-like growth factor-1 (IGF-1). In addition, HIF collaborates in complex ways with the oncogenic factor MYC to \"reprogram\" cellular metabolism in a way that ors growth. D", "cop": 1, "opa": "Clear cell", "opb": "Medullary", "opc": "Papillary", "opd": "Mixed type", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "540c9113-75e9-43d7-a867-597eca1b828d", "choice_type": "single"} {"question": "In Apoptosis , cytochrome C acts through", "exp": "ref, Robbins 8/e p29,9/e p55", "cop": 1, "opa": "Apaf1", "opb": "Bcl-2", "opc": "FADD", "opd": "TNF", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "77270a4c-4ddb-40cd-9cc3-6fe099a7c7bb", "choice_type": "single"} {"question": "Gluteus maximus is inserted on", "exp": "Ans. d (Iliotibial tract). (Ref. BD Chaurasia, Human Anatomy- Vol. II 3rd ed., 61)TENSOR FASCIA LATA# Tensor fascia lata lies between the gluteal region and front of the thigh.# It arises from anterior 5 cm of outer lip of iliac crest up to tubercle and from anterio superior iliac spine and notch below it. It is inserted into iliotibial tract.# It is supplied by superior gluteal nerve (L4, L5)# Ober's test is for testing its function", "cop": 4, "opa": "Lesser trochanter", "opb": "Greater trochanter", "opc": "Spiral line", "opd": "Iliotibial tract", "subject_name": "Anatomy", "topic_name": "Gluteal Region", "id": "d49783a9-1641-48eb-b962-14ad9738b0a1", "choice_type": "single"} {"question": "Injury to one of the following arteries results in extradural hematoma", "exp": null, "cop": 1, "opa": "Middle meningeal artery", "opb": "Facial artery", "opc": "Temporal artery", "opd": "Anterior cerebral artery", "subject_name": "Anatomy", "topic_name": null, "id": "336edfba-3e98-407a-a8f6-8ed257ab8c0f", "choice_type": "single"} {"question": "Nerve supply for adductor compartment of thigh is by", "exp": "(B) Obturator Nerve # OBTURATOR NERVE (L2, L3, L4) is the chief nerve of the medial compartment of the thigh.> It is a branch of the lumbar plexus.> It enters the thigh by passing through the obturator canal.> Anterior division of obturator nerve supplies the following muscles: Pectineus Adductor longus Gracilis Adductor brevis> Posterior division of obturator nerve supplies following muscles: Obturator externus Adductor magnus Adductor brevis", "cop": 2, "opa": "Femoral nerve", "opb": "Obturator nerve", "opc": "Superior gluteal nerve", "opd": "Inferior gluteal nerve", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "4ba28621-473d-482e-8b3a-6e502aa33b12", "choice_type": "single"} {"question": "The origin of ovaries from", "exp": null, "cop": 1, "opa": "Genital ridge", "opb": "Genital tubercle", "opc": "Wolffian duct", "opd": "Miillerian duct", "subject_name": "Anatomy", "topic_name": null, "id": "0e8ec33a-593f-40cb-a207-43f4fe18510c", "choice_type": "single"} {"question": "Early complication of TIPSS is", "exp": "Transjugular intrahepatic poosystemic stent shunts The emergency management of variceal haemorrhage has been revolutionised by the introduction of transjugular intrahepatic poosystemic stent shunts (TIPSS). Over a sho period, this has become the main treatment of variceal haemorrhage that has not responded to drug treatment and endoscopic therapy. The shunts are inseed under local anaesthetic, analgesia and sedation, using fluoroscopic guidance and ultrasonography. Via the internal jugular vein and SVC, a guidewire is inseed into a hepatic vein and through the hepatic parenchyma into a branch of the poal vein. The track through the parenchyma is then dilated with a balloon catheter to allow inseion of a metallic stent, which is expanded once a satisfactory position is achieved to form a channel between systemic and poal venous systems. A satisfactory drop in poal venous pressure is usually associated with good control of the variceal haemorrhage. The main early complication of this technique is perforation of the liver capsule, which can be associated with fatal intraperitoneal haemorrhage. TIPSS occlusion may result in fuher variceal haemorrhage and occurs more commonly in patients with well-compensated liver disease and good synthetic function. Post-shunt encephalopathy is a confusional state caused by the poal blood bypassing the detoxification of the liver. It occurs in about 40% of patients, a similar incidence to that found after surgical shunts. If severe, the lumen of the TIPSS can be reduced by inseion of a smaller stent. T he main contraindication to TIPSS is poal vein occlusion. The main long-term complication of TIPSS is stenosis of the shunt, which is common (approximately 50% at 1 year) and may present as fuher variceal haemorrhage. Ref: Bailey and love 27th edition pgno:1164", "cop": 2, "opa": "Encephalopathy", "opb": "Capsule rupture and bleeding", "opc": "Shunt stenosis", "opd": "Shunt thrombosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "21c5b038-7246-47e7-9ca3-fc554c8e5409", "choice_type": "single"} {"question": "Nerve damaged in case of numbness of little and ring finger, atrophy of hypothenar muscles", "exp": "Ans. c. Ulnar nerve before division into superficial and deep branchesNerve damaged in case of numbness of little and ring finger, atrophy of hypothenar muscles is ulnar nerve, before division into superficial and deep branches.Supplied musclesUlnar Nerve (C8T,)Musician's NervMedian Nerve (C5678T1)Laborer's nervedegAxilla and ArmNo branchNo branchForearmFlexor carpi ulnarisdegFlexor digitorum profundus(medial half)degFlexor carpi radialisFlexor digitorum profundus (lateral Flexor digitorum superficialisdegFlexor pollicis longusPalmaris longusPronator teres and quadratusdegHandLast two (3rd and 4th)lumbricalsdegPalmar and dorsal interosseidegThenar muscles:Adductor pollicisdegHypothenar muscles:Palmaris brevisAbductor digiti minimiFlexor digiti minimiOpponens digiti minimi1st two (1st and 2sd)lumbricalsdegThenar musclesAbductor pollicis b.revisdegFlexor pollicis brevisdegOpponens pollicisdeg", "cop": 1, "opa": "Palmar cutaneous branch of ulnar", "opb": "Deep branch of ulnar", "opc": "Ulnar nerve before division into superficial and deep branches", "opd": "Posterior cord of brachial plexus", "subject_name": "Anatomy", "topic_name": null, "id": "46ed639a-3cc0-4a2f-97d8-24280d191fb9", "choice_type": "single"} {"question": "Structure injured while resecting the free edge of lesser omentum is", "exp": "Lesser omentum: - It extends from liver to stomach (lesser curvature) and duodenum (first 2 cm). The pa of lesser omentum from liver to stomach is called hepatogastric ligament, and pa from liver to duodenum is called hepatoduodenal ligament. Hepatogastric ligament forms anterior free wall of lesser sac (omental bursa) and contains right and left gastric vessels, branches of gastric nerves and lymph vessels. Hepatoduodenal ligament forms right free margin, contains poal vein, hepatic aery proper, bile duct, lymphatics and hepatic plexus of nerves. Lesser omentum develops from ventral mesogastrium (dorsal pa).", "cop": 2, "opa": "Cystic duct", "opb": "Poal vein", "opc": "Left gastric aery", "opd": "Right gastroepiploic aery", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "8a1e3dd1-cbb9-432e-b6a4-829adf8155c5", "choice_type": "single"} {"question": "Lymphatic drainage of glans penis is by", "exp": "Lymphatic drainage of glans penis is deep inguinal lymph nodes. Superficial inguinal lymph nodes- scrotum, perineum, vulva and anus Lymphatic drainage of testis is pre and para aoic lymph nodes.", "cop": 2, "opa": "Superficial inguinal lymph nodes", "opb": "Deep inguinal lymph nodes", "opc": "Internal iliac lymph nodes", "opd": "Preaoic nodes", "subject_name": "Anatomy", "topic_name": "Abdominal wall ,Inguinal and Femoral region", "id": "9ecb13a1-fd05-420e-bdc7-fd8ea936e0fd", "choice_type": "single"} {"question": "Major complication of cysto gastrostomy for pseudopancreatic cyst", "exp": "Serious post op hemorrhage from cyst occurs from cysto gastrostomy Ref: CSDT 11th edition Pgno :638", "cop": 4, "opa": "Infection", "opb": "Obstruction", "opc": "Fistula", "opd": "Hemorrhage", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3e79abe7-9121-4f44-b0ea-7b08158d5bd3", "choice_type": "single"} {"question": "Most common hea valve involved in IV drug user is", "exp": "Ref Harrison 19 th ed pg 819 Almost 50% of endo- carditis associated with injection drug use is limited to the tricuspid valve and presents with fever but with faint or no murmur and no peripheral manifestations", "cop": 4, "opa": "Mitral valve", "opb": "Aoic valve", "opc": "Pulmonary valve", "opd": "Tricuspid Valve", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "eed04d00-6176-4481-93a9-17cf00a849e8", "choice_type": "single"} {"question": "Least common site for vegetation is", "exp": "Ref Harrison 19 th ed pg 820 Infection most commonly involves hea valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving aeriovenous shunts, aerio-aerial shunts (patent ductus aeriosus), or a coarctation of the aoa is called infective endaeritis.", "cop": 3, "opa": "Aerial stenosis", "opb": "Mitral stenosis", "opc": "Aerial septal defect", "opd": "Mitral regurgitation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fc198104-99a1-4b99-8cd1-bbb12c69e677", "choice_type": "single"} {"question": "Nerve involved most commonly in fracture neck of humerus is", "exp": "The axillary nerve ( C5,C6) passes close to surgical neck of humerus. -Supplies teres minor. Dislocation of shoulder or fracture of surgical neck of humerus can damage axillary nerve. Effects of damage- deltoid is paralyzed loss of power of abduction up to 90deg at shoulder, sensory loss over lower half of deltoid.", "cop": 4, "opa": "Musculocutaneous", "opb": "Median nerve", "opc": "Ulnar nerve", "opd": "Axillary nerve", "subject_name": "Anatomy", "topic_name": "Nerve supply, Nerve Lesions", "id": "a432cf5a-71ba-478b-8e35-8f8f2c5e3b67", "choice_type": "single"} {"question": "A highly ionized drug", "exp": "Ionized molecules cannot cross the biological membranes .therfore they are less likely to be absorbed . Entry of the molecules through blood brain barrier and blood placental barrier is also restricted .these drugs cannot be reabsorbed in the nephron,thus are excreted by the kidney . Refer kDT 7/e p29", "cop": 1, "opa": "Is excreted mainly by kidney", "opb": "Can carry placental barrier easily", "opc": "Is well absorbed from intestine", "opd": "Accumulates in cellular lipids", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ddd6de0-cc23-4250-8267-1d7dc8572d74", "choice_type": "single"} {"question": "Hyperextension at the metacarpophalangeal joints and flexion at the interphalangeal joints is caused by injury in the", "exp": "i.e. (Ulnar nerve): (59, 134-BDC-l 5th)An ulnar nerve lesion at the writ produces ulnar claw hand'CLAW HAND - due to the un opposed action of the long flexors and extension of the fingers, there is hyperextension at the metacarpo phalangeal joint and flexion at the interphalangeal joints involving the ring and little fingers - more than the index and middle fingers* If both median and ulnar nerves are paralysed the result is complete claw hand* Ulnar injury at the wrist can be tested by froment's sign", "cop": 1, "opa": "Ulnar nerve", "opb": "Radial nerve", "opc": "Median nerve", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper Extremity", "id": "e10e0352-c7a0-461c-b1c4-c5272f4c9a1b", "choice_type": "single"} {"question": "C wave in JVP indicates", "exp": "Ref Harrison 19 th ed pg 1485 The ' c' wave in JVP is a positive wave producd by the bulging of tricuspid Valve into the right atruat during right ventricular isovolumetric systils and by the impact of the carotid aery adjacent to the jugular vein.", "cop": 2, "opa": "Aerial contraction", "opb": "Bulging of tricuspid Valve", "opc": "Ventricle systole", "opd": "Rapid ventricular filling", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "968b2cf9-aa13-44ec-bf17-3df76903af95", "choice_type": "single"} {"question": "Root value of thoracodorsal nerve", "exp": "Thoracodorsal nerve or long thoracic nerve arises from brachial plexus. Its nerve value is C5, C6 and C7. REF:BDChaurasia 7th edition Page no: 57.", "cop": 1, "opa": "C5,C6,C7", "opb": "C6,T1", "opc": "C6,C7,C8", "opd": "T1,T2", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a44a527e-ab41-4554-876d-80bc279a8bf5", "choice_type": "single"} {"question": "Tissue f r om rat used for detection of antinuclear antibodies", "exp": "Serum antinuclear antibodies bind to corresponding antigents present in the rat liver section.the antigen-antibody complexes are detected by means of fluorescent labeled anti human immunoglbulin .and visualised with the aid of a fluorescence microscopy ref Robbins 9/e immunity chapter p131 and internet", "cop": 4, "opa": "Kidney", "opb": "Brain", "opc": "Stomach", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8d28ce14-92bb-4576-9223-1a6e709a8dc7", "choice_type": "single"} {"question": "Most commonest agent for Early Onset Nosocomial pneumonia is", "exp": "Early Onset Nosocomial pneumonia which manifest within the first 4 days of hospitalization,is most often caused by community acquired pathogens such as Streptococcus pneumoniae and Hemophilus species Hospital-acquired pneumonia (HAP) or nosocomial pneumonia refers to any pneumonia contracted by a patient in a hospital at least 48-72 hours after being admitted. It is thus distinguished from community-acquired pneumonia. It is usually caused by a bacterial infection, rather than a virus . Ref Harrison 19th edition pg 915", "cop": 1, "opa": "Hemophilus", "opb": "Staphylococcus aureus", "opc": "Pseudomonas", "opd": "Acinobacter", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "56d74b0c-2bd7-4dc9-a298-53c10d4dddd8", "choice_type": "single"} {"question": "Injury to the nerve originating from C5 in Brachial plexus leads to", "exp": "The question speaks of Dorsal scapular nerve on whose damage leads to winging of scapula.", "cop": 4, "opa": "Loss of abduction of the arm", "opb": "Loss of abduction of arm", "opc": "Loss of shrugging", "opd": "Winging of scapula", "subject_name": "Anatomy", "topic_name": null, "id": "4798c743-8cf8-4d88-af53-00a9f0f38233", "choice_type": "single"} {"question": "The term \"Dynamic stabilizer Of shoulder joint\" is used for", "exp": "ROTATOR CUFF:-Musculotendinous cuff Tendons of :1. Supraspinatus2. Infraspinatus3. Teres minor4. SubscapularisThey fuse with the underlying capsule of shoulder joint.Tendons of supraspinatus fuse superiorly.Infraspinatus& teres minor posteriorlySubscapularis anteriorly Functions:-1. Stabilise shoulder joint.2. Grasp relatively large head of the humerus and holds it against the smaller shallow glenoid cavity.{Reference: vishram singh, pg no. 74}", "cop": 1, "opa": "Rotator cuff", "opb": "Glenoid labrum", "opc": "Coracohumeral ligament", "opd": "Glenohumeral ligament", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "2be504bb-8bba-44c8-a623-3a7fc999fdbb", "choice_type": "single"} {"question": "Radial styloid process gives attachement to", "exp": "Extensor carpi ulnaris tendon traverses between the head of ulna and styloid process. Brachioradialis is inseed into the lowest pa of lateral surface just above the styloid process. Supinator is inseed into the upper pa of lateral surface . Anconeus is inseed into the lateral surface of olecranon process of ulna. B D Chaurasia 7th edition Page no: 18,138 Fig:2.14 page no 25 vishram Singh 2nd edition upper limb & thorax", "cop": 2, "opa": "Extensor carpi ulnaris", "opb": "Brachioradialis", "opc": "Supinator", "opd": "Anconeus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "1bbc5847-9656-45f6-b0ea-e51602f116a5", "choice_type": "single"} {"question": "Resistance to acyclovir is most commonly due to mutation in the viral gene that encodes a protein that", "exp": "Ref-KDT 6/e p768 Nucleoside/tide analogues act by conveing to NTPs. First phosphorylation step occurs inside the virus and resistance occurs if there is mutation in this gene", "cop": 2, "opa": "Conves viral RNA into DNA", "opb": "Phosphorylates acyclovir", "opc": "Transpos acyclovir into the cell", "opd": "Transpos acyclovir out of the cell", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "f2a1b0c8-7565-472d-a91c-cb1cca01765c", "choice_type": "single"} {"question": "Intestinal biopsy is not diagnostic in", "exp": "Refer Robbins page no 9/e 784 Small bowel biopsy is viually always abnormal when the tTG IgA antibody level is very high (more than five-fold the normal range), and EMA is positive. This is done in a procedure called a biopsy. The physician eases a long, thin tube called an endoscope through the mouth andstomach into the small intestine, and then takes samples of the tissue using small instruments passed through the endoscope.Biopsy remains the most accurate way to diagnose celiac disease", "cop": 2, "opa": "Abetalipoprotienemina", "opb": "Tropical sprue", "opc": "Intestinal lymphagienctaisis", "opd": "Agammaaglobinemia", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "94db41a4-0e72-4abb-89c0-bad8328d4caf", "choice_type": "single"} {"question": "The right suprarenal vein drains into the", "exp": "A i.e. Inferior vena cavaLeft testicular, ovarian or suprarenal vein usually drains into left renal veinQ, before entering the IVC OrganVeinDrain intoRt. Suprarenal glandRt. Suprarenal veinIVCQLt. Suprarenal glandLt. Suprarenal veinLeft Renal VeinQSame is true for gonads (testis /ovary) i.e.Lt. Gonad (testis or ovary)Lt. Gonadal (testicular or ovarian) veinLeft renal veinQRt. Gonad (testis or ovary)Rt. Gonadal (testicular or ovarian)veinIVCQ", "cop": 1, "opa": "Inferior vena cava", "opb": "Right renal vein", "opc": "Right Gonadal vein", "opd": "Left Renal vein", "subject_name": "Anatomy", "topic_name": null, "id": "5353469b-8bde-4db6-b796-318e6a2a469a", "choice_type": "single"} {"question": "Most commonly injured nerve in raised intracranial pressure", "exp": "MC nerve involved in increased ICT - Abducens (VI). Reasons : Longest intradural course Taking a sharp bend over apex of petrous pa of temporal bone. Passing through the cavernous sinus, not suppoed laterally by any dura mater.", "cop": 4, "opa": "3rd", "opb": "4th", "opc": "5th", "opd": "6th", "subject_name": "Anatomy", "topic_name": "Cranial Nerves", "id": "8fbee312-8b80-456e-81b9-a2a464a1ebda", "choice_type": "single"} {"question": "Haversian canal is not seen in", "exp": "Cancellous bone, also known as spongy or trabecular bone, is one of the two types of bone tissue found in the human body. Cancellous bone is found at the ends of long bones, as well as in the pelvic bones, ribs, skull, and the veebrae in the spinal column. Spongy bone consists of plates (trabeculae) and bars of bone adjacent to small, irregular cavities that contain red bone marrow. The canaliculi connect to the adjacent cavities, instead of a central haversian canal, to receive their blood supply Red bone marrow is where blood cells are made. Inderbir Singh&;s textbook of human Histology Seventh edition Pg no94 !1", "cop": 3, "opa": "Compact bone", "opb": "Diaphyseal bone", "opc": "Spongy bone", "opd": "Coical Bone", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "016154cc-a5eb-4b4a-a321-886674f33102", "choice_type": "single"} {"question": "Megaloblastic anemia due to folic acid deficiency is commonly due to", "exp": "Ref Harrison 19 th ed pg 646 Dietary folate deficiency is common. Indeed, in most patients with folate deficiency a nutritional element is present. Ceain individuals are paicularly prone to have diets containing inadequate amounts of folate (Table 128-5). In the United States and other countries where foification of the diet with folic acid has been adopted, the preva- lence of folate deficiency has dropped dramatically and is now almost restricted to high-risk groups with increased folate needs.", "cop": 1, "opa": "Inadequate dietary intake", "opb": "Defective intestinal absorption", "opc": "Absence of folic acid binding protein in serum", "opd": "Absence of glutamic acid in the intestine", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "71c6f23f-21bc-405f-8664-e7558c0fd2b2", "choice_type": "single"} {"question": "Michaelis Guttmannn bodies are present in", "exp": "Ref Robbins 9/e p693 Michaelis-Gutmann bodies are concentrically layered basophilic inclusions found in the urinary tract. They are 2 to 10 mm in diameter, and are thought to represent remnants of phagosomes mineralized by iron and calcium deposits.", "cop": 3, "opa": "Analgesic nephropathy", "opb": "Him and ulcer", "opc": "Malacoplakia", "opd": "Erythroplasia", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "445b6c79-2fc9-4e26-939e-ec39f4e0fd28", "choice_type": "single"} {"question": "Absence of lymph nodes is characteristic of", "exp": "The brain, pa of the central nervous system, has blood vessels but has been thought to lack lymphatic vessels, as they've never been found in humans . Ref - researchgate.net", "cop": 1, "opa": "Brain", "opb": "Liver", "opc": "Lung", "opd": "Placenta", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ed1a7a2c-e064-482b-9ca5-4d6e990278a0", "choice_type": "single"} {"question": "The nerve of the second branchial arch is", "exp": "Each pharyngeal arch is characterized by its own muscular components. The muscular components of each arch have their own cranial nerve, and wherever the muscle cells migrate, they carry their nerve commponent with them. The neurons of 5th, 77th, 9th and 10th cranial sensory ganglia that supply the pharyngeal arch structures are derived from the ectodermal placodes (epipharyngeal placodes) and from the neural crest cells. Arch Nerve Skeletal derivatives Pouch Derivatives Muscle Derivatives Aery 1st (Mandibular arch) Trigeminal (V) Incus Malleus Anterior ligament of malleus Spine of sphenoid Sphenomandibular ligament Auditory tube Middle ear cavity Tensor tympani Muscles of mastication Mylohyoid Anterior belly of digastric Tensor veli palatini maxillary aery 2nd (hyoid arch) Facial (VII) Stapes Styloid process (temporal) Lesser cornu and upper hyoid Stylohyoid ligament palatine tonsil Tonsillar fossa Stapedius Stylohyoid Facial muscles (Buccinator, platysma, posterior belly of diagastric) Stapedial aery Hyoid aery 3rd Glossopharyngeal (IX) Greater cornu of hyoid Lower pa of hyoid pa Inferior parathyroids Thymus Stylopharyngeus Common carotid Proximal internal carotid aeries 4th Supeiror laryngeal of vagus (X) Thyroid cailage Corniculate cailage Cuneiform cailage Superior parathyroids Parafolliculae C cells of thyroid (from ultimobranchial body) Pharyngeal muscles Larynx-cricothyroid Levator veli palatini Right side : Right subclan aery (proximal poion) Left side: Arch of the aoa from the left common carotid to the left subclan aeries 6th Recurrent laryngeal nerve of Vagus (X) Arytenoid cailages All intrinsic muscles of the larynx (except the crciothyroid muscle) Right side: Right pulmonary aery Left side: Pulmonary aery and ductus aeriosus Ref: Langman's Medical embryology 14th edition Pgno: 284, 289", "cop": 3, "opa": "Glossopharygeal nerve", "opb": "Trigeminal nerve", "opc": "Facial nerve", "opd": "Vagal nerve", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d991137f-d5c2-495b-8b48-aa37eac865a5", "choice_type": "single"} {"question": "The structure derived from neural crest is", "exp": "The neural crest is the region from where the pigment cells(melanoblasts) of skin develop. Ref: Inderbir Singh's Human embryology; Tenth edition; Pg 327 Mnemonic:SOME GAP S-Schwann cells -Skeleton of face O-odontoblasts M-Meninges(pia and arachnoid) E-Endocardial cushion G-Ganglia(autonomic and dorsal root ganglia) A-Adrenal medulla -Aoicopulmonary septum P-Pigmant cells(melanocytes) -Pharyngeal arches(nerves and cailage) -parafollicular c cells of thyroid", "cop": 3, "opa": "Retina", "opb": "Cauda equina", "opc": "Melanocytes", "opd": "Adrenal coex", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "10d9ada4-36d4-4b0a-bb9e-1a4d6fc2716c", "choice_type": "single"} {"question": "Kasai's procedure is the treatment of choice for", "exp": "Treatment of Biliary atresia Exploratory laparotomy: If needle biopsy or abdominal ultrasound is consistent with BA Intra operative cholecystocholangiography : To confirm diagnosis, demonstration of fibrotic biliary remnant and definition of absent proximal and distal bile duct patency Treatment of choice : Kasai's hepatopooenterostomy (Roux-en-Y hepaticojejunostomy Ref: Sabiston 20th edition Pgno : 639", "cop": 3, "opa": "Congenital hyperophic pylori stenosis", "opb": "Duodenal atresia", "opc": "Biliary atresia", "opd": "Hirschprung's disease", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1a624d6f-39e7-490c-9acc-5a4f648c8bd1", "choice_type": "single"} {"question": "Herniation of midgut during embryogenesis persists until", "exp": "This midgut herniation persists until about 10 weeks of fetal gestation, when the intestine returns to the abdominal cavity Ref: Sabiston 20th edition Pg no : 1237", "cop": 2, "opa": "6 weeks", "opb": "10 weeks", "opc": "16 weeks", "opd": "20 weeks", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f3aabbd4-2ae9-4a9b-999d-24868a5a2519", "choice_type": "single"} {"question": "Length of CBD", "exp": ".", "cop": 3, "opa": "2.5 -5 cm", "opb": "5-7 cm", "opc": "7-11 cm", "opd": "10-15 cm", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "a0dd14a6-fc40-459d-9f1b-083a873fe47b", "choice_type": "single"} {"question": "The optic nerve is a tract of the diencephalon that is not completely myelinated until", "exp": "The axons of the optic nerve are not completely myelinated until 3 months after bih. Myelinated axons are normally not found in the retina. The optic nerve is not a true peripheral nerve but a tract of the diencephalon; when severed, the optic nerve does not regenerate. Myelination in the central nervous system (CNS) is accomplished by oligodendrocytes; oligodendrocytes are not found in the retina.", "cop": 4, "opa": "5 years after bih", "opb": "2 years after bih", "opc": "1 year after bih", "opd": "3 months after bih", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "dd62cf00-2acd-4703-956a-2659f361bd97", "choice_type": "single"} {"question": "The type of joint encircled", "exp": "The joint encircled in Zygapophyseal joint. It is a type of plane Synovial joint.", "cop": 4, "opa": "Fibrous joint", "opb": "Condylar joint", "opc": "Saddle joint", "opd": "Plane Synovial joint", "subject_name": "Anatomy", "topic_name": null, "id": "62e5a5bd-7622-4c80-bee5-1f0c7815267b", "choice_type": "single"} {"question": "Recurrant interosseous aery is a branch of", "exp": "Near its origin , posterior interosseous aery gives off interosseous recurrent aery which runs upwards , and ends by anastomosing with middle collateral aery behind lateral epicondyle . B D Chaurasia 7th edition Page no : 113", "cop": 1, "opa": "Posterior interosseous aery", "opb": "Anterior interosseous aery", "opc": "Radial aery", "opd": "Ulnar aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "de8e50d7-ed01-42ce-ab55-47a89da851dc", "choice_type": "single"} {"question": "CD 56 is a marker of", "exp": "Ref : Robbins 8/ep29-30,9/e p56", "cop": 2, "opa": "Intrinsic pathway of apoptosis", "opb": "Extrinsic pathway of apoptosis", "opc": "Necrosis of cell", "opd": "Cellular adaptation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "69de2418-ca50-4c0c-be13-2f5ce89d69fe", "choice_type": "single"} {"question": "In angina pectoris, the pain radiating down the left arm is mediated by increased activity in afferent (sensory) fibres contained in the", "exp": "D. i.e. Thoracic splanchnic nerves", "cop": 4, "opa": "Carotid branch of the glossopharyngeal nerve", "opb": "Phrenic nerve", "opc": "Vagus nerve & recurrent laryngeal nerve", "opd": "Thoracic splanchnic nerve", "subject_name": "Anatomy", "topic_name": null, "id": "1d605184-b9c0-43e6-87a5-e6fca692c801", "choice_type": "single"} {"question": "Venous blood of liver is drained by", "exp": "The poal vein and hepatic aeries form the liver's dual blood supply. After draining into the liver sinusoids, blood from the liver is drained by the hepatic vein. Ref - Researchgate.net", "cop": 4, "opa": "Poal vein", "opb": "Hepatic aery", "opc": "Sinusoids", "opd": "Hepatic veins", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "83bd3571-3a81-478d-9a8a-0cbbcd8f6bb2", "choice_type": "single"} {"question": "Footplate of stapes is developed from", "exp": "The stapes is formed from the dorsal end of the cailage of the second pharyngeal arch. The ossicles are at first outside the mucous membrane of the developing ear. The foot process of stapes develops from the otic capsule. Inderbir Singh's; Human embryology; Tenth edition; Pg 368", "cop": 2, "opa": "Meckel's cailage", "opb": "Otic capsule", "opc": "Reiches cailage", "opd": "Hyoid arch", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9d4ac487-0e27-496f-bac6-fa8ee4ae68b4", "choice_type": "single"} {"question": "Nerve supply of Trapezius", "exp": "TRAPEZIUS: Origin: medial 1/3 rd of superior nuchal line., ligamentum nuchae, external occipital protuberance and spines of C7-T12 veebrae. Inseion:-lateral 1/3rd of clavicle., medial margin of acromion,superior margin of spine of scapula. Nerve supply: spinal accessory( motor),C3,C4 spinal nerves ( proprioceptive). Action:- upper fibres elevate scapula,'middle fibres retract ,and lower fibres depress scapula. {Reference: vishram singh, pg no. 72}", "cop": 1, "opa": "Spinal accessory nerve", "opb": "Hypoglossal nerve", "opc": "Trochlear nerve", "opd": "Trigeminal nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "080b8b82-9b28-4b6a-9e53-54dc0151ba88", "choice_type": "single"} {"question": "Normal volume of adult testis", "exp": "Ans. is 'c' i.e., 15-20 ml\"Normal adult testicular volume is 15-20 ml, calculated by the formula : length x width x depth x 0.52 = volume\" -- Grainger.", "cop": 3, "opa": "5-10 ml", "opb": "10-15 ml", "opc": "15-20 ml", "opd": "25-30 ml", "subject_name": "Anatomy", "topic_name": null, "id": "f2ad33e1-38f4-47cf-89ac-e83e490f10be", "choice_type": "single"} {"question": "Knudsen's two hit hypothesis is for", "exp": "Knudson gave the hypothesis that there are two mutations needed for Retinoblastoma to manifest. Either both hits are on somatic cells or one is at the somatic cells and one is at germ cell. Respectively, it can be sporadic or a hereditary case Refer khurana 6/e p 303", "cop": 2, "opa": "Glaucoma", "opb": "Retinoblastoma", "opc": "Optic glioma", "opd": "Meningioma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2741becb-fc3f-4aa0-a85c-75773ca3b600", "choice_type": "single"} {"question": "The daos muscle is innervated by", "exp": "It is a sheet of smooth muscle. It arises from the layer superficial to the superficial fascia. It arises superficially to inse into the skin and midline fibrous raphae of the scrotum. It is innervated by the sympathetic fibres from the genital branch of the genitofemoral nerve. ref - BDC 6e vol2", "cop": 3, "opa": "Ilioinguinal nerve", "opb": "Iliohypogastric nerve", "opc": "genitofemoral nerve", "opd": "Pudendal nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fe6107e6-3d02-4cd5-84a1-e316299eccaf", "choice_type": "single"} {"question": "ATT drug causing contact lens stainig is", "exp": "refer Goodman Gilman 12th/1553 Rifamipicin cause discolouration (orange) of secretions leading to control lens5 staining", "cop": 2, "opa": "INH", "opb": "Rifamipicin", "opc": "Streptomycin", "opd": "Pyrazinamide", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5e3b0a8a-5b95-4c26-a4cc-3e01b6050abc", "choice_type": "single"} {"question": "Failure of the choroid fissure to close results in", "exp": "Failure of the choroid (optic) fissure to close results in a cleft of the iris--called coloboma iridis (mostly in inferonasal position). This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia--absence of the lens--may result from defective development of the lens placode.", "cop": 4, "opa": "Congenital detached retina", "opb": "Congenital aniridia", "opc": "Congenital aphakia", "opd": "Coloboma iridis", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "a90c98cd-45f2-4267-b932-7290d77c72dc", "choice_type": "single"} {"question": "Not a feature of Quadrangular space syndrome", "exp": "Quadrangular space syndrome Hypertrophy of the quadrangular space muscles or fibrosis of the muscle edges may impinge on the axillary nerve. Uncommonly this produces waekness of the deltoid muscle. Typically it produces atrophy of the teres minor muscle. Which may affect the control that the rotator cuff muscles exert on shoulder movement.", "cop": 4, "opa": "Hypertrophy of quadrangular space syndrome", "opb": "Weakness of abduction of the arm", "opc": "Weakness of lateral rotation of the arm", "opd": "Weakness of medial rotation of the arm", "subject_name": "Anatomy", "topic_name": null, "id": "9c69efa1-e76b-4214-a8c5-6d7c756d4bbf", "choice_type": "single"} {"question": "The given histological specimen is of", "exp": null, "cop": 2, "opa": "Thymus", "opb": "Spleen", "opc": "Lymph node", "opd": "Seminal vesicles", "subject_name": "Anatomy", "topic_name": null, "id": "48b1cd75-24f5-43e2-8b8a-8d7831c0a12d", "choice_type": "single"} {"question": "The Thymus is located in", "exp": "The thymus is a bilobed structure, made up of two pyramidal lobes of unequal size which are connected together by areolar tissue. Each lobe develops from the endoderm of the third pharyngeal pouch. It lies on the pericardium, the great vessels of the superior mediastinum, and the trachea. Small detached thymic nodules may be found in the neck.Ref: BD chaurasia; Volume 3; 6th edition; Page no: 172", "cop": 1, "opa": "Superior mediastinum", "opb": "Middle mediastinum", "opc": "Posterior mediastinum", "opd": "Anterior mediastinum", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "52b512df-f79e-490b-8e24-1cfd5bac7095", "choice_type": "single"} {"question": "Pringle maneuver may be required for treatment of", "exp": "Explanation in previous question Ref: Sabiston 20th edition Pgno : 439 Blumga 5th edition pgno : 1547", "cop": 4, "opa": "Injury to tail of pancreas", "opb": "Mesentric ischaemia", "opc": "Bleeding esophageal varices", "opd": "Liver laceration", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0b29a1a7-7907-418d-823b-61228d8fc205", "choice_type": "single"} {"question": "Anterior interventricular aery is a branch of", "exp": "LEFT CORONARY AERY It is larger than the right coronary aery.It arises from the left posterior aoic sinus. Branches A.Large branches 1.Anterior interventricular 2.Branches to the diaphragmatic surface of the left ventricle,including a large diagonal branch. B.Small branches 1.Left atrial 2.Pulmonary 3.Terminal REF.B D Chaurasia's human anatomy vol.1.fifth edition BD CHAURASIA'S HUMAN ANATOMY.VOL.1.FIFTH EDITION.PAGE NO 252", "cop": 2, "opa": "Right coronary aery", "opb": "Left coronary aery", "opc": "Circumflex aery", "opd": "Left anterior descending aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "08c69f87-fbc7-4e84-99cf-6bad6eea0983", "choice_type": "single"} {"question": "need for thinness inspite of being lean is a feuture of", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "anorexia nervosa", "opb": "bulimia nervosa", "opc": "metabolic syndrome", "opd": "binge eating", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "665f972a-3ede-4202-b7e4-c56cf9604f8b", "choice_type": "single"} {"question": "Poor prognostic factor in acute pancreatitis", "exp": "Ranson's prognostic criteria for Non-gallstone pancreatitis At admission Age >55 years WBC >16000 cells/mm3 Blood glucose >200mg/dl Serum LDH>350IU/L AST >250 U/L During initial 48hours Hematocrit fall >10 percentage points. BUN elevation >5mg/dl Serum calcium fall to <8mg/dl Aerial pO2<60 mmHg Base deficit >4mEq/L Estimated fluid sequestration >6 litres Ranson's prognostic criteria for gallstone pancreatitis At admission Age >70 years WBC >18000 cells/mm Glucose >220mg/dl Serum LDH >400IU/L AST >250U/L During initial 48 hours Hematocrit fall >10 percentage points BUN elevation >2mg/dl Serum calcium fall to <8mg/dl Base deficit >5mEq/L Aerial pO2<60 mmHg Estimated fluid sequestration >4 litres Patients with one or two criteria have a predicted moality of less than 1%, with three criteria (10%) of four criteria (15%) with more than seven criteria 50% Ref: Sabiston 20th edition Pgno : 1527-1528", "cop": 2, "opa": "Decreased serum amylase", "opb": "Decreased calcium", "opc": "Increased blood sugar", "opd": "Increased PaO2", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "559744d1-c8ff-4caa-9d50-ac026e41a328", "choice_type": "single"} {"question": "The marker for Langerhans cells Histiocytes is", "exp": "Refer Robbins page no 8th edition 631-632 The tumor cells express HLA-DR and CD 1a Langerhans cell histiocytosis (LCH) is a clonal disorder believed to be derivedfrom cells of the dendritic system. Fascin, a 55-kd actin-bundling protein, represents a highly selective marker for dendritic cells of lymphoid tissues and peripheral blood and is involved in the formation of dendritic processes in maturing epidermal Langerhans cells. Since lesional cells of LCH may represent Langerhans cells arrested at an early stage of activation, immunohistochemical expression offascin in epidermal Langerhans cells and in the lesional cells of 34 cases of LCH was evaluated in paraffin sections using an immunoalkaline phosphatase technique. Though epidermal Langerhans cells were nonreactive for fascin, lesional cells in all LCH cases exhibited immunoreactivityforfascin, CD1a, and S-100 protein. Variation in staining intensity was observed in some cases, possibly reflecting differences in cell maturation or activation. Involved tissues included bone, soft tissue, lymph node, thyroid, orbit, and extradural cranial tissue. Immunoreactivity of lesional cells of LCH for fascin suppos their derivation from cells of the dendritic system and represents another alteration in the phenotype of Langerhans cells that is associated with maturation, migration, culture, or clonal expansion", "cop": 1, "opa": "CD 1a", "opb": "CD 20", "opc": "CD 3", "opd": "CD 30", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "0c802f60-fe1b-4770-9973-dd7217dce737", "choice_type": "single"} {"question": "Risk of HIV transmission is not seen with", "exp": "* Intravenous drug abusers with no history of homosex- ual behavior compose the next largest group, represent- ing about 17% of all patients. * Recipients of blood and blood components (but not hemophiliacs) who received transfusions of HIV- infected whole blood or components (e.g., platelets, plasma) account for about 1% of patients. * Hemophiliacs, especially those who received large amounts of factor VIII or IX concentrates before 1985, make up less than 1% of all cases. * The epidemiology of HIV infection and AIDS is quite different in children (diagnosed when younger than 13 years of age). About 1% of all AIDS cases occur in this population, and the vast majority (about 90%) result from veical transmission of virus from infected mother to the fetus or newborn Ref Robbins 9/e P244", "cop": 3, "opa": "Whole blood", "opb": "Platelets", "opc": "Plasma derived hepatitis B vaccine", "opd": "Leucocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7f2a7bf7-4617-4eb4-850d-9c156b371f98", "choice_type": "single"} {"question": "In head and neck the parasympathetic system in\ninnervates the", "exp": null, "cop": 4, "opa": "Salivary glands only", "opb": "Lacrimal glands only", "opc": "Salivary and mucous glands", "opd": "Salivary and lacrimal glands", "subject_name": "Anatomy", "topic_name": null, "id": "90a7c043-ddd2-44f6-b568-cddbecb06df1", "choice_type": "single"} {"question": "Auerbach plexus is present in the", "exp": "The cells of the Auerbach's (myenteric) plexus are located between the inner circular and outer longitudinal layers of the muscularis externa. These nerve cells are the poion of the enteric nervous system responsible for generating peristaltic movements. Ref - medscape.com", "cop": 3, "opa": "Mucosa layer", "opb": "Submucosa layer", "opc": "Muscular layer", "opd": "Serosa layer", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "b8937a5f-26d0-4276-910d-b1a2a5123f96", "choice_type": "single"} {"question": "Sensation not represented in sensory coex is", "exp": "Olfaction is represented in the olfactory coex (Brodmann's area 28) which is located in the anterior pa of the parahippocampal gyrus and uncus. Note: Primary sensory area-pain, touch, Vibration, Temperature, muscle and joint sense. sensory association area- stereognosis. (Ref: Vishram Singh textbook of clinical neuroanatomy, second edition pg- 151)", "cop": 4, "opa": "Pain", "opb": "Temperature", "opc": "Touch", "opd": "Olfaction", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "d0360c88-6b07-48e1-8cc0-87ac45eea4db", "choice_type": "single"} {"question": "Muscles of mastication develops from", "exp": null, "cop": 1, "opa": "1st branchial arch", "opb": "2nd branchial arch", "opc": "3rd branchial arch", "opd": "6th branchial arch", "subject_name": "Anatomy", "topic_name": null, "id": "26daa193-f5ea-4ec3-97c9-dac9b02d4e21", "choice_type": "single"} {"question": "Function of hepatic kupffer cells is", "exp": "Kupffer cells Kupffer cells, derived from the macrophage - monocyte system Are irregular stellate - shaped cells that also line the sinusoids, insinuating between endothelial cells Phagocytic, play a major role in the trapping of foreign substances and initiating an inflammatory response MHC-II antigens are expressed on kupffer cells but do not confer efficient antigen presentation compared with macrophages elsewhere in the body Ref: Sabiston 20th edition Pgno :1430", "cop": 4, "opa": "Formation of sinusoids", "opb": "Vitamin A storage", "opc": "Increase blood perfusion", "opd": "Phagocytosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b72c63bd-6177-421c-9acc-60d27e1c8c63", "choice_type": "single"} {"question": "In humour cells meiosis take place at", "exp": "MEOSIS TAKES PLACE IN GONADS . REF : EMBRYOLOGY VISHRAM SINGH", "cop": 2, "opa": "Adrenal", "opb": "Adult ovary", "opc": "prepubeal testes", "opd": "Hypothalamus", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "f687fb8b-02c6-4085-9943-10e92f647a07", "choice_type": "single"} {"question": "Functional unit of Liver is", "exp": "Anatomical unit of liver - Hepatic Lobule Functional unit of liver- Liver Acinus", "cop": 3, "opa": "Hepatocytes", "opb": "Poal Tracts", "opc": "Liver Acinus", "opd": "Hepatic Lobule", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "a11d6f28-7147-4a50-9745-41499c36a2b8", "choice_type": "single"} {"question": "Delusion that nothing exists in this world is", "exp": "Nihilistic delusion It is the delusion of hat nothing exists in the world, even he doesn't exist. This type of delusion may be seen in endogenous depression and bipolar disorder. Ref: FORENSIC MEDICINE ANad TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 359", "cop": 2, "opa": "Delusion of influence", "opb": "Nihilistic delusion", "opc": "Delusion of self reproach", "opd": "Erotomania", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "414ed457-8213-4a21-b100-811fd391bbcd", "choice_type": "single"} {"question": "Following is not a feature of AIDS related lymphadenopathy", "exp": "Ref Robbins 9/e p256 Early stages of HIV reveal a marked follicular hyperplasia Monocytoid cells along the blood vessels can be seen in acute lymphadenitis With the disease progession_ severe follicular involution is seen During the advanced stage - viral burden in the nodes reduces in pa because of the disruption of follicular dendritic cells ..These burnt out lumph nodes are atropic and small", "cop": 3, "opa": "Florid reactive hyperplasia", "opb": "Follicle lysis", "opc": "Haematoxylin bodies", "opd": "Collection of monocytoid B cells in sinuses", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d82c112d-8265-43da-a7b4-f24853ee3096", "choice_type": "single"} {"question": "NOT an abductor of hip joint", "exp": "Gluteus maximus chiefly performs Extension and lateral rotation\nGluteus medius, Gluteus minimus and Tensor fascia lata -Abduction and medial rotation", "cop": 3, "opa": "Gluteus medius", "opb": "Gluteus minimus", "opc": "Gluteus maximus", "opd": "Tensor fascia lata", "subject_name": "Anatomy", "topic_name": null, "id": "befdf640-638b-4532-817b-0abe7cdb005b", "choice_type": "single"} {"question": "Cavernous sinus communicates with", "exp": "Draining channels or communications the cavernous sinus drains: 1.into the transverse sinus through the superior petrosal sinus. 2.into the internal jugular vein through the inferior petrosal sinus and through a plexus around the internal carotid aery. 3. into the pterygoid plexus of veins through the emissary veins passing through the foramen ovals, the foramen lacerum, and the emissary sphenoidal foramen 4. In to the facial vein through the superior ophthalmic vein. 5.the right and left cavernous sinuses communicate with each other through the anterior and posterior intercavernous sinuses and through the basilar plexus of veins. Notes: all these communications are valveless and blood can flow through them in either direction Ref: BDC volume3;Sixth edition pg 195", "cop": 1, "opa": "Superior petrosal sinus", "opb": "Inferior petrosal sinus", "opc": "Superior ophthalmic vein", "opd": "Middle meningeal vein", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "49acf5af-293e-4976-9663-22970825fe09", "choice_type": "single"} {"question": "Base of Submental triangle is formed by", "exp": "Boundaries of Sub Mental Triangle Apex - Symphysis Menti Base - Hyoid Bone On each side - Anterior belly of Digastric Content - Sub Mental nodes Floor - Mylohyoid", "cop": 3, "opa": "Chin", "opb": "Omohyoid", "opc": "Hyoid", "opd": "Diagastric", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "f4085a61-ab74-4e40-a39e-a63fa28580d6", "choice_type": "single"} {"question": "Somatic innervation to the pelvic organs is", "exp": "For most of its pelvic course, the femoral nerve (L2, L3, L4) travels within the substance of the psoas muscle and then exits its lateral side to pass under the inguinal ligament. It supplies sensation to the anterior thigh and motor innervation to the extensors of the knee.", "cop": 3, "opa": "Greater splanchnic nerve", "opb": "Lesser splanchnic nerve", "opc": "Pudendal nerve", "opd": "Ilioinguinal nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "a2aeba83-437c-44bf-bb05-8081baa44e98", "choice_type": "single"} {"question": "At 30 days of intrauterine life", "exp": "*Optical vesicle come in contact with surface ectoderm and lens place is forming by the 4th week of IUL - the eyes begin to develop as a pair of diveicula from the lateral aspects of the forebrain. These diveicula make their appearance before the closure of the anterior end of the neural tube; after the closure of the tube, they are known as the optic vesicles. *Ear pinna or auricle stas forming by the 5th week of IUL *Cerebellum stas forming by the 8th week of IUL *The baby's heabeat stas as the blood flow begins by 22nd day of IUL (Reference: I B Singh's Embryology, 10th edition, pg 374, 281)", "cop": 3, "opa": "Hea stas beating", "opb": "Cerebellum develops", "opc": "Optical vesicle appears", "opd": "Pinna appears", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4b1181d3-d9b9-460d-b60a-bd8896dda4fd", "choice_type": "single"} {"question": "Macrophage of Central Nervous System includes", "exp": "(B) Microglia # Microglia are tissue macrophages that populate the mammalian central nervous system (CNS) very early in embryonic development. By adulthood, microglia are found in all regions of the brain and spinal cord and comprise 10-15% of the total cells in the CNS.", "cop": 2, "opa": "Astrocytes", "opb": "Microglia", "opc": "Neuron'", "opd": "Oligodendrocyte", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "44778600-9e4a-499a-ae29-bbe3886f0dd2", "choice_type": "single"} {"question": "Area that lies immediately lateral to the anterior perforating substance is", "exp": "The limen insulae is the Antero-inferiorly located insular coical surface which conjoins the inferior insular point, the anterior perforated surface, and the temporo mesial surface.", "cop": 4, "opa": "Orbital gyrus", "opb": "Uncus", "opc": "Optic chiasma", "opd": "Limen insulae", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "4437ecfe-4e0b-49d1-9608-5cab3ef162a8", "choice_type": "single"} {"question": "Connecting Stalk forms", "exp": "Connecting Stalk forms primary Umbilical Cord .", "cop": 1, "opa": "primary umblical cord", "opb": "secondary umblical cord", "opc": "decidua paritalis", "opd": "decidua capsularis", "subject_name": "Anatomy", "topic_name": "General Embryology 1", "id": "3d23e393-ae91-407d-af61-9f5621bbab48", "choice_type": "single"} {"question": "Intramuscular injection of atropine causes initial bradicardia. The reason for this effective being seen is", "exp": "Ref-KDT 6/e p107 Atropine is a non-selective antagonist of M1, M2, and M3 muscarinic receptors. M2, cholinergic receptors are responsible for bradycardia and blockade of these receptors can result in tachycardia. Atropine initially acts on presynaptic M1, receptors (normally decrease the release of ACh) and result in greater release of ACh which is responsible for bradycardia. Later on, blockade of M2 receptors will lead to tachycardia.", "cop": 4, "opa": "Stimulation of medullary vagal centre", "opb": "Stimulation of vagal ganglia", "opc": "Blockade of ME receptor and SA nodal cells", "opd": "Blockade of muscarinic auto receptor on vagal nerve ending", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "304a43bb-c15e-432d-9306-3bf43791727a", "choice_type": "single"} {"question": "Pulsation felt in the suprasternal space are probably due to", "exp": null, "cop": 3, "opa": "Subclavian artery.", "opb": "CCA.", "opc": "Inferior thyroid artery.", "opd": "Vertebral artery.", "subject_name": "Anatomy", "topic_name": null, "id": "f888fdd0-cd3f-415d-b082-832ccd427494", "choice_type": "single"} {"question": "Drug of choice for septic shock is", "exp": "Septic shock produces more VD so noradrenaline which is a powerful vasoconstrictor is used.", "cop": 4, "opa": "Dopamine", "opb": "Dobutamine", "opc": "Droxidopa", "opd": "Nor adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f8cf15c8-bef5-4cf8-93ce-672cfcfa176c", "choice_type": "single"} {"question": "Most common malignant bone tumors", "exp": "Metastatic tumors are the most common form of skeletal malignancy. Refer Robbins page no 8/e 1236p", "cop": 2, "opa": "Osteogenic sarcoma", "opb": "Secondaries", "opc": "Osteoma", "opd": "Enchondroma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "eec86058-bcb6-4ff6-907c-880153f3105f", "choice_type": "single"} {"question": "Hyaline Cailage extends upto", "exp": "Hyaline Cailage extends upto Bronchus", "cop": 2, "opa": "Trachea", "opb": "Bronchus", "opc": "Respiratory Bronchioles", "opd": "Terminal Bronchioles", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "f058727d-0057-4284-8238-27bdc43e1dd2", "choice_type": "single"} {"question": "Lymphatics from the spongy urethra drain into the following lymph nodes", "exp": "It drains into deep injuinal lymph node . Ref - bdc 6e vol2 pg376-379", "cop": 3, "opa": "Superior inguinal nodes", "opb": "Internal inguinal nodes", "opc": "Deep inguinal nodes", "opd": "Sacral nodes", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "73f89185-f4b1-42b2-a500-3cc783f7391c", "choice_type": "single"} {"question": "Spontaneous regression though rare is seen in", "exp": "Neuroblastoma is a cancer often found in the small glands on top of the kidneys (adrenal glands). It can develop in the stomach, chest, neck, pelvis and bones. Children aged five or younger are most commonly affected. Most children with neuroblastoma in Noh America have been treated according to the In the previous COG risk system, each child was assigned to a low-risk, intermediate-risk, or high-risk group (refer to Tables INSS stage. Age. International Neuroblastoma Pathologic Classification (INPC). Ploidy. Amplification of the MYCN oncogene within tumor tissue.[Other biological factors that influenced treatment selection in previous COG studies included unbalanced 11q loss of heterozygosity and loss of heterozygosity for chromosome 1p.[Generally, treatment is based on whether the tumor is classified as low, intermediate, or high risk, as follows: Low risk. For patients with low-risk tumors, the approach is either observation or resection, with chemotherapy restricted to symptomatic patients with low-risk biology. Five-year overall survival (OS) was 97% in a large COG study.[Intermediate risk. For patients with intermediate-risk tumors, chemotherapy is often given before definitive resection, and the number of chemotherapy cycles is based on clinical and tumor biological risk factors and response to therapy. In recent studies, select patients have been observed without undergoing chemotherapy or attempted resection. The 3-year OS rate for intermediate-risk patients was about 96% in a large COG study.[High risk. For high-risk patients, treatment has intensified to include chemotherapy, surgery, radiation therapy, myeloablative therapy and stem cell transplant (SCT), isotretinoin, and immunotherapy, resulting in survival rates of about 50%. Statistically significant improvement in survival was observed in a randomized phase III COG study ( COG Risk-Group Assignment Treatment Options COG = Children's Oncology Group; GM-CSF = granulocyte-macrophage colony-stimulating factor; 131I-MIBG = iodine I 131-metaiodobenzylguanidine; SCT = stem cell transplant. Recurrent Neuroblastoma Locoregional recurrence in patients initially classified as low risk Metastatic recurrence in patients initially classified as low risk Locoregional recurrence in patients initially classified as intermediate risk Metastatic recurrence in patients initially classified as intermediate risk Recurrence in patients initially classified as high risk Recurrence in the central nervous system . Refer robbins 8/e p477", "cop": 3, "opa": "Burkits lymphoma", "opb": "Wilms tumor", "opc": "Neuroblastoma", "opd": "Melanoma", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "36d98e71-9448-44e5-af7f-4c3d25b3c2e7", "choice_type": "single"} {"question": "Investigation of choice for hydatid disease is", "exp": "Diagnosis is confirmed by Serological tests for antibodies like ELISA Immunoblot Arc-5 IHA", "cop": 2, "opa": "CT scan", "opb": "ELISA", "opc": "Biopsy", "opd": "USG", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3c844565-cb22-4d33-a826-527779239d7d", "choice_type": "single"} {"question": "Blood supply of liver", "exp": "The liver revives 20 % of blood supply through hepatic aery,80% through poal vein B D CHAURASIA'S HUMAN ANATOMY LOWER LIMB ABDOMEN PELVIS VOLUME2-SIXTH EDITION Page no-307", "cop": 2, "opa": "80 % hepatic aery, 20 % poal vein", "opb": "20 % hepatic aery, 80 % poal vein", "opc": "50 % hepatic aery, 50 % poal vein", "opd": "100 % hepatic aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "062d2d3c-8fc4-4bb1-9f9a-806bf89d35c3", "choice_type": "single"} {"question": "Normal anteflexion of uterus", "exp": "Normally the uterus lies in anteversion & anteflexion. Fuhermore, the long axis of the body of the uterus is bent forward at the level of the internal os with the long axis of the cervix. This position is termed anteflexion of the uterus. ref - BDC 6e vol2 pg 387", "cop": 3, "opa": "90 o", "opb": "100 o", "opc": "125 o", "opd": "140 o", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9e4b823d-ad42-439c-88b9-3d52b7c7f6e8", "choice_type": "single"} {"question": "Meckel's cailage develops from", "exp": "The cailage of the first arch is called Meckel's cailage. the incus and malleus are derived from its dorsal end. the ventral pa of the mandible is surrounded by the developing mandible and is absorbed Ref: Human Embryology, Inderbir Singh, 10th edition, page no: 131", "cop": 1, "opa": "I branchial arch", "opb": "II branchial arch", "opc": "III branchial arch", "opd": "IV branchial arch", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ca2254a6-ebb3-4f40-a07e-7b7f48b038b1", "choice_type": "single"} {"question": "Otic ganglia are related to", "exp": "Otic ganglion is a peripheral parasympathetic ganglion which relays secretomotor fibres to the parotid gland. Topographically, it is intimately related to the mandibular nerve, but functionally it is a pa of the glossopharyngeal nerve. The motor or parasympathetic root is formed by the lesser petrosal nerve. The preganglionic fibres are derived from the inferior salivary nucleus - the ninth nerve, its tympanic branch, the tympanic plexus -the lesser petrosal nerve to reach the ganglion. The postganglionic or secretomotor fibres pass through the auriculotemporal nerve to the parotid gland. The sympathetic root is derived from the plexus on the middle meningeal aery. The sensory root comes from the auriculotemporal nerve and is sensory to the parotid gland. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 6th edition 127,311", "cop": 1, "opa": "9th nerve", "opb": "10th nerve", "opc": "8th nerve", "opd": "7th nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ba5ee350-3005-4799-986a-23166d47c195", "choice_type": "single"} {"question": "Enzyme that protects the brain from free radical injury is", "exp": "Superoxide dismutase ref Robbins 7/e p17 , Harrison 17/e p 2572 ,9/e p48.", "cop": 2, "opa": "Myeloperoxidase", "opb": "Superoxide dismutase", "opc": "MAO", "opd": "Hydroxylase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "30e81409-3e3c-4e5f-8684-43eff5a85f17", "choice_type": "single"} {"question": "Excision of hyoid bone is done in", "exp": "Thyroglossal Cyst Cystic swelling developed in the remnant of the thyroglossal duct or tract Present in any pa of the thyroglossal tract (extends from foramen caecum to isthmus of thyroid) Common sites Subhyoid (MC) Floor of mouth Region of thyroid cailage Suprahyoid Beneath the foramen caecum Clinical features It is a midline swelling, except in the region of thyroid cailage, where thyroglossal tract is pushed to one side, usually to the left Though its a congenital swelling MC age of presentation is between 15 and 30 years Cyst can be moved sideways but not veically Peculiar characteristics which helps in distinguishing thyroglossal cyst from other neck swelling Moves up with protrusion of tongue as the thyroglossal tract is attached to the tongue Moves with deglutition so do all thyroid swellings, subhyoid bursitis Cyst is lined by pseudostratified columnar epithelium and squamous epithelium with hetero topic thyroid tissue present in 20% of cases Complications Recurrent infections Formation of thyroglossal fistula Carcinomatous change (papillary carcinoma) Treatment Sistrunk operation : En-bloc cystectomy and excision of central hyoid bone to minimize recurrence Ref: Sabiston 20th edition Pgno :1861", "cop": 4, "opa": "Sublingual dermoids", "opb": "Ludwig's angina", "opc": "Branchial cyst", "opd": "Thyroglossal cyst", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "7d372669-485e-4c71-bf9c-fd0018f30f69", "choice_type": "single"} {"question": "Germs cells derived from", "exp": "All the germ layers ectoderm, meroderm and endoderm derived from epiblast.", "cop": 1, "opa": "Epiblast", "opb": "Hypoblast", "opc": "Endodermal sinus", "opd": "Neural crest cells", "subject_name": "Anatomy", "topic_name": null, "id": "79ccbdbf-457b-42c6-9cfa-92c84958d208", "choice_type": "single"} {"question": "mood stabilizer used in the management of depression", "exp": "Lamotrigine is a mood stabilizer which works best in BIPOLAR DEPRESSION Lithium is a mood stabilizer which works best in BIPOLAR MANIA valproate is a mood stabilizer which works best in RAPID CYCLING Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, 935", "cop": 1, "opa": "lamotrigine", "opb": "valproate", "opc": "carbamezepine", "opd": "lithium", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "ac1610af-f580-4ef6-a9aa-855086fd9617", "choice_type": "single"} {"question": "The most abundant glycoproteins present in basement membrane is", "exp": "Lamininis the most abundant glycoproteins in the basement membrane .the type 4 collagen .laminin and nidrogen are present in basement mem Ref.robbins Harrison.17/e p2462", "cop": 1, "opa": "Laminin", "opb": "Fibronectin", "opc": "Collagen type 4", "opd": "Heparan sulphate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d8a2f817-770d-48b5-8c7b-5fcdb2ae015e", "choice_type": "single"} {"question": "Opening of the nasolacrimal duct is in", "exp": "Ans. is 'a' i.e. Inferior meatus Openings in the lateral wall of nasal cavity *Inferior meatus : Nasolacrimal duct*Middle meatus : Anterior ethmoidal sinus*Frontal sinus*Maxillary sinus*Superior meatus : Posterior ethmoidal sinuses*Sphenoethmoidal recess : Sphenoid sinus*Note: that the nasolacrimal duct opens into the inferior meatus but if its blocked and a DCR (Dacryocystorhinostomy) operation is performed the new opening is in the middle meatus*", "cop": 1, "opa": "Inferior meatus", "opb": "Superior meatus", "opc": "Middle meatus", "opd": "Sphenoethmoidal recess", "subject_name": "Anatomy", "topic_name": "Nose", "id": "6a839fe5-4d56-4cf7-81a5-2a5eb749b256", "choice_type": "single"} {"question": "Most common muscle damaged in rotator cuff is", "exp": "Refer Williams Vil 1.p 330 The tendons of the rotator cuff, not the muscle are most commonly involved and of the four, The supraspinatus us effected most frequently as it passes below the acromian", "cop": 1, "opa": "Supraspinatus", "opb": "Infraspinatus", "opc": "Subsacapularis", "opd": "Teres minor", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "594d3070-e4bd-44ba-824a-693ef24b00c9", "choice_type": "single"} {"question": "Punched out ulcer in oesophagus on endoscopy in a immunocompromised patient is seen in", "exp": "Dysphagia and odynophagia are the symptoms caused by herpes. There may be history of heretic lesion on lip some days earlier. Endoscopy reveals vesicles or small ulcers with raised margins, usually in the upper half of the oesophagus. Ref: Bailey and love 27th edition Pgno: 1104", "cop": 2, "opa": "Herpes zoster virus", "opb": "Herpes simplex virus", "opc": "Cytomegalo virus", "opd": "Candidiasis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "43755eb8-4682-4cd0-b515-904c15e55e37", "choice_type": "single"} {"question": "Structure not forming watershed area", "exp": "Watershed area is the medical term referring to regions of the body that receive dual blood supply from the most distal branches of two large aeries, such as the splenic flexure of the large intestine. Watershed areas are found in the brain, where areas are perfused by both the anterior and middle cerebral aeries, and in the intestines, where areas are perfused by both the superior and inferior mesenteric aeries (i.e., splenic flexure). Additionally, the sigmoid colon and rectum form a watershed zone with blood supply from inferior mesenteric, pudendal and iliac circulations. Hypoperfusion in watershed areas can lead to mural and mucosal infarction in the case of ischemic bowel disease. When watershed stroke occurs in the brain, it produces unique focal neurologic symptoms that aid clinicians in diagnosis and localization.", "cop": 3, "opa": "Splenic flexure", "opb": "Brain", "opc": "Duodenum", "opd": "Sigmoid colon - rectum", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8418f9d8-1671-4409-8fa2-be03da3c3608", "choice_type": "single"} {"question": "blue grey discolouration of skin", "exp": "chlorpromazine is a typical anti psychotic that has lot of mentioned side effects namely Blue grey discolouration of skin reverse lens granular deposits obstructive jaundice retrograde ejaculation REf. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 925", "cop": 1, "opa": "chlorpromazine", "opb": "risperisone", "opc": "memantine", "opd": "clozapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "e9e56117-2026-44cc-a848-2624b8e5b0e0", "choice_type": "single"} {"question": "Solitary hypoechoic lesion of the liver without septa or debris is most likely to be", "exp": "A solitary hypoechoic lesion without any septae or debris is most likely to be a simple cyst. However rarely a hydatid cyst can have a similar sonologic appearance. Simple cysts are the most common benign lesions found in liver. On imaging studies they appear as unilocular, homogenous fluid-filled structures with a thin wall without projections, septa or debris. Ultrasound appearances of - Hydatid cyst - It presents either as a simple cyst with hydatid sand or daughter cysts or floating endocyst or calcification. Caroli's disease - Its the type V choledochal cyst Multiple intrahepatic biliary cysts are seen on ultrasound. Sludge & stones may also be visible within the cysts. Liver abscess - Sonographic appearance may include a cystic lesion with floating internal echoes and irregular margins. Septations, debris and fluid-fluid interfaces may also be seen. Ref : Rumack's Diagnostic Ultrasound 3rd/e, p. 86, 89, 94, 1865", "cop": 4, "opa": "Hydatid cyst", "opb": "Carolis disease", "opc": "Liver abscess", "opd": "Simple cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8da3de02-aaf6-4f08-b23f-093ed9475c54", "choice_type": "single"} {"question": "Hypogastric sheath is a condensation of", "exp": "The hypogastric sheath is a pelvic fassia condensation. It lies along the posterolateral pelvic wall and carries the neurovascular bundles towards the pelvic visera. It also provides the pelvic visera suppo. image ref - wikipedia.org", "cop": 3, "opa": "Scarpa's fascia", "opb": "Colle's fascia", "opc": "Pelvic fascia", "opd": "Inferior layer of urigenital diaphragm", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ef8c584c-b56c-407d-b92c-f7d91289fbc0", "choice_type": "single"} {"question": "Posterior ethmoidal sinus drains into (JIPMER May 2019)", "exp": "- There are 3 groups of ethmoidal air sinuses Anterior Middle Posterior - Posterior ethmoidal sinus is opening in lateral wall of the nose. - Lateral wall of the nose has 3 elevations called superior, middle & inferior turbinates / conchae - Under each turbinate, there is space called meatus called superior, middle & inferior meatus - Posterior ethmoidal sinus is opening in superior meatus - Anterior & middle sinus is opening in middle meatus - Middle meatus have hiatus semilunaris At front of hiatus semilunaris frontal air sinus opens The anterior, middle ethmoidal sinus respectively Maxillary sinus opens slightly posterior; In the region of hiatus semilunaris in middle meatus - Naso-lacrimal duct opens in the inferior meatus on Anterior aspect - Inferior turbinate is largest turbinate & its meatus is largest meatus - Eustachian tube opens behind inferior turbinate in lateral wall of nasopharynx", "cop": 2, "opa": "Spheno-ethmoidal recess", "opb": "Superior meatus", "opc": "Middle meatus", "opd": "Inferior meatus", "subject_name": "Anatomy", "topic_name": "JIPMER 2019", "id": "3b909ad5-c40f-4013-85df-1a402a8b9fc4", "choice_type": "single"} {"question": "Fracture of the proximal humerus in an elderly patient is best treated by", "exp": "(Refer: Watson Jones Textbook of Ohopedics & Trauma, 6thedition,pg no: 536-538)", "cop": 2, "opa": "K-wire fixation", "opb": "Open reduction internal fixation", "opc": "Cuff and sling only", "opd": "Manual reduction and Slab application", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3929c339-da3c-42c1-af76-7bf2e814e70d", "choice_type": "single"} {"question": "Shoest pa of colon", "exp": "ascending colon 15 cm descending colon 25 cm transverse colon 50 cm sigmoid colon;40 cms The ascending colon is the first of four sections of the large intestine. It is connected to the small intestine by a section of bowel called the cecum. The ascending colon runs upwards through the abdominal cavity toward the transverse colon for approximately eight inches.One of the main functions of the colon is to remove the water and other key nutrients from waste material and recycle it. As the waste material exits the small intestine through the ileocecal, it will move into the cecum and then to the ascending colon where this process of extraction stas. Ref - BDC vol2 6e pg271-273", "cop": 1, "opa": "Ascending colon", "opb": "Transverse colon", "opc": "Descending colon", "opd": "Sigmoid colon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "cd67993d-d546-4fcf-954f-562fd4a6a039", "choice_type": "single"} {"question": "dihydroerigotamine differs from ergotamine in the following respect", "exp": "hydrogenation of ergot alkaloids decrease their vasoconstrictor action and increase the Alpha blocking activity Ref-KDT 6/e p168", "cop": 4, "opa": "It is more potent oxytocic", "opb": "it has antimetic propey", "opc": "it has high oral bioavailability", "opd": "it is more potent alpha adrenergic blocker and less potent vasoconstrictor", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "9470fd74-c4d0-4e9d-8785-3e859dcf7d20", "choice_type": "single"} {"question": "Capitonnage is used in treatment of", "exp": "Methods of management of the residual cavity after cyst evacuation External tube drainage Capsulorrhaphy Capitonnage Myoplasty Omentoplasty Internal collapse Introflexion Marsupialization Introflexion plus omentoplasty Cysto jejunostomy or cysto gastrostomy Ref: Blumga 5th edition Pg no : 1045", "cop": 3, "opa": "Choledochal cyst", "opb": "Dermoid cyst", "opc": "Hydatid cyst", "opd": "Renal cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "9102f825-4f57-4133-b938-af6356661b14", "choice_type": "single"} {"question": "A patient with AIDS and a CD4 cell count of 100/ul , has a persistent fever and Weight Loss associated with invasive pulmonary disease due to M avium complex. Optimal management of this case requires", "exp": "Ref-KDT 6/e p750 Mycobacterium avium complex infection is treated with combination of rifabutin,ethambu eth and clarithromycin", "cop": 3, "opa": "Select an antibiotic regimen based on drug susceptibility of the cultured organism", "opb": "Sta treatment with isoniazide and rifampicin", "opc": "Treat the patient with clarithromycin,ethambutol and rifabutin", "opd": "Treat with trimethoprim sulfamethoxazole", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "62777be4-4267-4f29-bae3-e5c660539f2c", "choice_type": "single"} {"question": "A three years old boy presents with the poor urinary stream. Most likely cause is", "exp": "Poor urinary stream in 3 years old boy suggests urinary tract obstruction (usually intravesical) and the most common cause of obstructive uropathy in a male child is posterior urethral valve. Posterior urethral valve These are symmetrical folds of urothelium extending distally from prostatic urethra to external urinary sphincter. It most commonly lies just distal to the verumontanum or at the verumontanum* It occurs only in males. It behaves as flap valves so, although urine does not flow normally a urethral catheter can be passed without difficulty. Sometimes, the valves are incomplete and the patient remains without symptoms until adolescence or adulthood. Approximately 30% of patients experience end stage renal disease Vesicoureteral reflux occurs in 50% of patients. Diagnosis is made by voiding cystourethrogram* & endoscopy Both of these investigations clearly depict the site of obstruction. The diagnosis can be established prenatally by ultrasound.* Management First, a small polyethene feeding tube is inseed in the bladder and left for several days. Then fuher management is done according to serum creatinine level. with normal serum creatinine - transurethral ablation of the valve leaflets. * With increased serum creatinine and the worsening of condition - vesicostomy to bypass the obstruction and when normal creatinine levels are achieved, transurethral ablation is done. Ref : Bailey & Love 25/e 1362", "cop": 4, "opa": "Stricture urethra", "opb": "Neurogenic bladder", "opc": "Urethral calculus", "opd": "Posterior urethral valve", "subject_name": "Anatomy", "topic_name": "Urology", "id": "e1fdecec-a609-41b2-abf2-43f185f3aa21", "choice_type": "single"} {"question": "Anti ds DNA antibiodies are commonly seen in", "exp": "Antibiodies to do DNA and the so called Smith antigens are viually diagnostic of SLE .Anti ds-,DNA is common in SLE (40-60%,) ref Robbins 9/e p 128", "cop": 1, "opa": "SLE", "opb": "Scleroderma", "opc": "Dermatomyositis", "opd": "Rheumatoid ahritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "790234ca-a6da-4d31-a98a-50045bea622a", "choice_type": "single"} {"question": "If the 4th infralabial is larger than others on either side, the snake may be", "exp": "If the 3rd supra labial is not touching eye and nasal shield, then look at the ventral aspect of head. If the 4th infra labial is larger than the others on either side, it is poisonous (krait) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 511", "cop": 2, "opa": "Cobra", "opb": "Krait", "opc": "Viper", "opd": "Coral snake", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "a689bcc2-3e3a-45a8-8903-9af52dbe758c", "choice_type": "single"} {"question": "The Broca's area is situated in the", "exp": "(B) Inferior frontal gyrus # BROCA'S AREA is a section of the human brain that is involved in language processing, speech or sign production, and comprehension.> Broca's area is located in the opercular and triangular sections of the inferior frontal gyrus of the frontal lobe of the cortex.> Broca's and Wernicke's areas are found unilaterally in the brain (left hemisphere).> Broca's area comprises Brodmann area 44 and (according to some authorities) Brodmann area 45.> Broca's Area is connected to Wernicke's area by a neural pathway called the arcuate fasciculus.", "cop": 2, "opa": "Temporal lobe", "opb": "Posterior part of Inferior frontal gyrus", "opc": "Occipital calcarine fissure", "opd": "Mammillary body region", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "64d6a4df-357e-46d4-a071-994d3e7d25e8", "choice_type": "single"} {"question": "Suture present between parietal & occipital bones is", "exp": "The lambdoid suture lies between the occipital bone and the two parietal bones. Sutural bones are common along this suture. Lambdoid sutures are usually visible clearly. The lambdoid suture traverses the posteriormost pa of the skull. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 1, "opa": "Lambdoid suture", "opb": "Saggital suture", "opc": "Coronal suture", "opd": "Metopian suture", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9b0bec46-792b-4995-befa-e3c458c0af86", "choice_type": "single"} {"question": "Conjoint tendon is formed by", "exp": "CONJOINT TENDON:- Falx inguinalisFormation: fusion of lowest aponeurotic fibres of internal oblique and of the transversus muscle. Medially : continuous with the anterior wall of rectus sheath.Laterally: free It may be continuous with an inconstant ligamentous band, interfoveolar ligament,which connects lower border of transversus abdominis to the superior ramus of pubis. Conjoint tendon strengthens the anterior abdominal wall at site where it is weakened by the superficial inguinal ring. {Reference: BDC 6E}", "cop": 3, "opa": "External oblique, internal oblique", "opb": "External oblique, transversus abdominis", "opc": "Internal oblique, transversus abdominis", "opd": "Rectus abdomnis, transversus abdominis", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "2a1d0229-3780-4e5e-9587-49dc018f4364", "choice_type": "single"} {"question": "Preganglionic supply to the submandibular gland is", "exp": "The sensory root is from the lingual nerve. It is suspended by two roots of lingual nerve.The sympathetic root is from the sympathetic plexus around the facial aery. This plexus contains postganglionic fibers from the superior cervical ganglion of the sympathetic trunk. These fibers pass express through the ganglion and are vasomotor to the submandibular glandThe secretomotor root is from superior salivatory nucleus through nervous intermedius chords tympani which is a branch of cranial nerve VII. Chorda tympani joins lingual nerve. The parasympathetic fibers get relayed in the submandibular ganglion.Ref: BD Chaurasia; volume 3; 6th edition; Page no: 308", "cop": 3, "opa": "Otic ganglion", "opb": "Geniculate ganglion", "opc": "Superior salivary nucleus", "opd": "Inferior salivary nucleus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "44e6828f-cf88-47db-86bd-95f69bdc8e3e", "choice_type": "single"} {"question": "Structures passing between superior and middle constrictor muscles are", "exp": "Stylopharyngeus muscle and glossopharyngeal nerve are structures passing between superior and middle constrictors of pharynx.", "cop": 3, "opa": "Superior laryngeal vessels, internal laryngeal nerve", "opb": "Stylopharyngeus muscle, superior laryngeal vessels", "opc": "Glossopharyngeal nerve, stylopharyngeus muscle", "opd": "Internal laryngeal nerve, stylopharyngeus muscle", "subject_name": "Anatomy", "topic_name": null, "id": "a003fe4c-13bd-4976-8680-e2b08b181ca9", "choice_type": "single"} {"question": "Ansa cervicalis supplies", "exp": "Ansa cervicalis supplies to the sternohyoid, the sternothyroid, and the inferior belly of the omohyoid Notes; ansa cervicalis is a thin nerve loop that lies embedded in the anterior wall of the carotid sheath over the lower pa of the larynx.it supplies the infrahyoid muscles Ref: BDC volume 3;Sixth edition pg 103", "cop": 3, "opa": "Cricothyroid", "opb": "Stylohyoid", "opc": "Sternohyoid", "opd": "Mylohyoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "e73765fb-12fe-4d09-9e21-55a3a1182266", "choice_type": "single"} {"question": "Facial vein communicates with the cavernous sinus through", "exp": null, "cop": 4, "opa": "Retromolar vein and internal jugular vein", "opb": "External jugular vein and internal jugular vein", "opc": "Internal jugular vein and retromandibular vein", "opd": "Superior ophthalmic vein and pterygoid venous plexus", "subject_name": "Anatomy", "topic_name": null, "id": "6773f2fb-dcdd-4b92-888f-53593304c16e", "choice_type": "single"} {"question": "Stain used for the diagnosis of granulocytic sarcoma", "exp": ".", "cop": 1, "opa": "Myeloperoxidase", "opb": "Leucocyte alkaline phosphatase", "opc": "Non specific esterase", "opd": "Neuron specific esterase", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "bc1682e3-8a3f-43a9-98cb-a3b205d357e3", "choice_type": "single"} {"question": "Patients with chronic pancreatitis gives chain of lakes appearance in ERCP examination. Management is", "exp": "Surgical procedures in chronic pancreatitis Ideal procedure : DPPHR(Beger's procedure) In presence of poal vein thrombosis : Frey's Small duct disease : V- Shaped excision Disease recurrence in body and tail (after DPPHR, Whipple's or Longmire-Transverso procedure) : V-shaped drainage Disease limited to tail: Spleen - preserving distal pancreatectomy Ref: Sabiston 20th edition Pgno :1535", "cop": 3, "opa": "Total pancreatectomy", "opb": "Sphicteroplasty", "opc": "Side to side pancteaticojejunostomy", "opd": "Resecting the tail of pancreas and performing a pancteaticojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "91662407-9e6a-49aa-9402-a166bdeb231b", "choice_type": "single"} {"question": "Froments sign is seen in", "exp": "Froments sign, or the book test tests the adductor pollicis muscle. When the patient is asked to grasp a book firmly between the thumbs and other fingers of both hands, the terminal phalanx of thumb on the paralysed side becomes flexed at the interphalangeal joint (by the flexor pollicis longus which is supplied by median nerve)", "cop": 1, "opa": "Ulnar nerve palsy", "opb": "Median nerve palsy", "opc": "Anterior interosseous nerve palsy", "opd": "Radial nerve palsy", "subject_name": "Anatomy", "topic_name": null, "id": "b6a8aefb-e88e-4a2d-81c1-d5e3b63e9889", "choice_type": "single"} {"question": "The lowest rib level reached by the parietal pleura in the midaxillary line is", "exp": "C. i.e. Tenth", "cop": 3, "opa": "Eighth", "opb": "Ninth", "opc": "Tenth", "opd": "Eleventh", "subject_name": "Anatomy", "topic_name": null, "id": "99618cee-f770-4995-9f57-63be4ab788f4", "choice_type": "single"} {"question": "Storage form of iron", "exp": "Ref Robbins 9/e p650 The normal total body iron mass is about 2.5 g for women and 3.5 g for men. Approximately 80% of func- tional body iron is present in hemoglobin, with the remain- der being found in myoglobin and iron-containing enzymes (e.g., catalase, cytochromes). The iron storage pool, consist- ing of hemosiderin and ferritin-bound iron in the liver, spleen, bone marrow, and skeletal muscle, contains on average 15% to 20% of total body iron. Because serum fer- ritin is largely derived from this storage pool, the serum ferritin level is a good measure of iron stores. Assessment of bone marrow iron is another reliable but more invasive method for estimating iron stores. Iron is transpoed in the plasma bound to the protein transferrin. In normal persons, transferrin is about 33% saturated with iron, yielding serum iron levels that average 120 ug/dL in men and 100 ug/dL in women. Thus, the normal total iron-binding capacity of serum is 300 to 350 ug/dL.", "cop": 1, "opa": "Ferritin", "opb": "Transferrin", "opc": "Hepcidin", "opd": "Ferropoin", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "3f328334-bd3d-4bfb-ab00-4e91ecf74fd2", "choice_type": "single"} {"question": "Muscle responsible for opening of mandibular", "exp": "Masseter and medial pterygoid form a amuscular sling which holds and suspends the mandible. By cambining the actions of both muscles in to a functional unit, this sling enables powerful closure of the jaws.", "cop": 1, "opa": "Lateral pterygoid", "opb": "Medial pterygoid", "opc": "Temporalis", "opd": "Buccinators", "subject_name": "Anatomy", "topic_name": null, "id": "425f5934-b901-406b-973c-751c4efa9684", "choice_type": "single"} {"question": "Presence of nephroblastomatosis in a biopsy specimen from Wilm's tumor of left kidney indicates high possibility of", "exp": "Presence of nephrogenic rests (nephroblastomatosis) in resected specimen indicates an increased risk of developing Wilm's tumor in contralateral kidney. Nephrohlastomatosis also k/a \"nephrogenic rests\" or nodular renal blastema, refer to the abnormal persistence of embryonal renal tissue. These are supposed to be precursor lesions of Wilm's tumor. These are seen in renal paraenchyma adjacent to tumors in approx. 25% to 40% of unilateral and 100% of bilateral tumors. Presence of nephrogenic rests in resected specimen indicates an increased risk of developing Wilm's tumor in contralateral kidney. So these patients will require frequent and regular radiological surveillance with CT scan for many years. Ref : Nelson Pediatrics 18/e p2140-2143", "cop": 3, "opa": "Denys-Drash syndrome", "opb": "Mutation in insulin like growth factor", "opc": "Increased risk of tumor in right kidney", "opd": "Lymph node metastasis", "subject_name": "Anatomy", "topic_name": "Urology", "id": "ea837356-857a-4d06-b263-ff61ed5fda84", "choice_type": "single"} {"question": "atypical depression is managed with", "exp": "MAOI * IMPOANCE First class of antidepressant drugs that were introduced * MECHANISM There are three monoamines namely dopamine, adrenaline and serotonin. These mon amines are degraded by monoamine oxidase. MAOI inhibit this enzyme and acts increasing monoamines * DRUGS Phenelezine Tranylcipromine * USE ATYPICAL DEPRESSION, depression with reverse vegetative symptoms * SIDE EFFECTS Hypeensive crisis Cheese reaction When a patient on MAOI takes tyramine rich food like tyramine there will be increased release of monoamines. These excess monoamines cannot be degraded by MAO as it is blocked by MAOI. Thus, this may result in hypeensive crisis. Paresthesia's due to pyridoxine deficiency LIKE IPRONIAZID WEIGHT gain SEXUAL dysfunction ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 966", "cop": 1, "opa": "MAOI", "opb": "SSRI", "opc": "NDRI", "opd": "SNRI", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "98b93160-ef90-41b9-902b-a92dfd59763c", "choice_type": "single"} {"question": "Inversion of foot is at", "exp": "C. i.e. Talocalcaneal joint", "cop": 3, "opa": "Talocalcaneonavicular joint", "opb": "Calcaneocuboid joint", "opc": "Talocalcaneal joint", "opd": "Inferior tibiofibular joint", "subject_name": "Anatomy", "topic_name": null, "id": "52f4ab9b-7c18-4f58-897a-a54c73703718", "choice_type": "single"} {"question": "In genetic deficiency of MPO the increased susceptibility to infections is due to", "exp": "Ref Robbins 8/e p53 ,56,9/e p76 Myeloperoxidase (MPO) is a hemoprotein expressed in azurophilic granules of neutrophils and in the lysosomes of monocytes. The enzyme has strong antibacterial propeies and is unique in its ability to generate potent bactericidal compounds such as hypochlorous acid (HOCl) from hydrogen peroxide and the halide, chloride", "cop": 3, "opa": "Defective production of prostaglandin", "opb": "Defective rolling of neutrophil", "opc": "Inability to produce hydroxyl halide radicals", "opd": "Inability to produce hydrogen peroxide", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "417d7423-fd0e-45f6-9f65-00d952adf93b", "choice_type": "single"} {"question": "Ebsteins anomaly is a side effect of", "exp": "side effects of mood stablizers are impoant questions to be asked in entrance examination lithium causes Ebstiens anamoly valproate causes neural tube side effects Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, 935", "cop": 1, "opa": "lithium", "opb": "carbamezepine", "opc": "valproate", "opd": "lamotrigine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "11c07702-7164-45e8-8e3f-74ea4109e629", "choice_type": "single"} {"question": "Plague epidemic in Surat in 1995 has occurred after a 'silence period' of", "exp": "The last case of plague in India was repoed in 1966 and after that there was a 'silence period' of 28 years till the reappearance of the disease in September 1994, when there was an outbreak of bubonic plague in Beed district of Maharashtra and pneumonic plague in Surat (Gujarat).", "cop": 3, "opa": "18 years", "opb": "23 years", "opc": "28 years", "opd": "30 years", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cfb916d1-1d99-4207-8278-1cc72de700c3", "choice_type": "single"} {"question": "Naloxone is the physiological antidote of", "exp": "Naloxone is the physiological antidote. It competes with opioids at the receptor sites and reverses their action. It can reverse not only the respiratory, analgesic, and euphoric actions but the dysphoric, delusional and hallucinatory propeies also. Naloxone in the dose of 2 mg i.v can be taken and repeated every 20-30 minutes, upto a total dose of 10 mg. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 488", "cop": 4, "opa": "Alcohol", "opb": "Cocaine", "opc": "Barbiturates", "opd": "Opium", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "3ae2f868-7574-444d-b71f-7f6cdc91401f", "choice_type": "single"} {"question": "A patient is admitted with severe pain in the abdomen, nausea, vomiting and fever. The most likely diagnosis", "exp": "Clinical features of acute pancreatitis Cardinal symptoms : Epigastric and /or peri umbilical pain that radiates to the back, relieved by sitting & leaning forward Upto 90% of patients have nausea and/or vomiting that typically does not releive on pain Nature of the pain is constant Dehydration, poor skin turgor, tachycardia, hypotension & dry mucous membranes are commonly seen in patients with AP Mild-pancreatitis: Abdomen may be normal of reveal only mild epigastric tenderness Severe pancreatitis : Significant abdominal distension, associated with generalised rebound tenderness and abdominal rigidity Flank (Grey Turner), peri umbilical (cullen's sign) & inguinal ecchymosis (Fox sign) are indicative of retro peritoneal bleeding associated with severe pancreatitis Dullness to percussion and decreased breathing sounds in left or less commonly, in the right hemithorax suggest pleural effusion Ref: Sabiston 20th edition Pgno :1524-1528", "cop": 3, "opa": "Perforated peptic ulcer", "opb": "Intestinal obstruction", "opc": "Acute pancreatitis", "opd": "Acute cholecystitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "22d659d4-2707-4f87-b9cd-63ff7c9924de", "choice_type": "single"} {"question": "The type of suture represented by sagittal suture of the cranial vault is", "exp": "The joints in the skull are mostly sutures.\nVarious types of sutures in the skull are,\n\nPlane suture - Eg. Internasal suture, mid palatal suture.\nSerrated suture - Eg. Sagittal and coronal suture (interparietal suture).\nDenticulate suture - Tooth like projections. Eg. Lambdoid suture.\nSquamous suture - Eg. Parieto-temporal suture.", "cop": 1, "opa": "Serrate", "opb": "Denticulate", "opc": "Squamous", "opd": "Plane", "subject_name": "Anatomy", "topic_name": null, "id": "6fb940fa-195e-4e4c-96b6-cba99d416a46", "choice_type": "single"} {"question": "Most common type of Supracondylar fracture in children is", "exp": "Extension type is the most common type (97-99 percnt) and the most commonest displacement of distal fragment is Posteromedial (70-80 percnt)", "cop": 1, "opa": "Posteromedial extention", "opb": "Posterolateral extension", "opc": "Anterimedial flexion", "opd": "Anterolateral flexion", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "507fc40f-d3f8-46f9-adf7-f82aa3cec6bd", "choice_type": "single"} {"question": "Nephrocalcinosis in a systemic granuomatous disease is due to", "exp": "Ref Robbins 8/e p 433-436 Nephrocalcinosis, once known as Albright's calcinosis after Fuller Albright, is a term originally used to describe deposition of calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate. It may cause acute kidney injury", "cop": 1, "opa": "Over production of 1,25 dihydroxy vitamine D", "opb": "Dystrophic calcification", "opc": "Mutation in calcium sensing receptors", "opd": "Increased reabsorption of calcium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7575e4dc-a149-44fa-b0db-1ba402cada7b", "choice_type": "single"} {"question": "The sensation of posterior aspect of tongue is by", "exp": "The glossopharyngeal nerve is the nerve for both general sensation and taste for the posterior one third of the tongue including the circumvallate papillae.The posterior most pa of the tongue is supplied by the vagus nerve through the internal laryngeal branch.The sensory supply of anterior two thirds is lingual nerve where as the taste sensation from the anterior two thirds is carried out by chorda tympani except vallate papillae(pre-trematic branch of first arch). REF.BDC VOL 3,Fifth edition.", "cop": 1, "opa": "Glossopharyngeal nerve", "opb": "Vagus nerve", "opc": "Hypoglossal nerve", "opd": "Mandibular nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f78d8d8c-6cab-443b-ab27-31e022aa4f67", "choice_type": "single"} {"question": "According to pughs classification moderate to severe hepatic insufficiency is managed by", "exp": "Patient of cirrhosis with variceal bleeding or ascites can be controlled by shunt surgery only if he falls in CTP class A or B Moderate to severe grade liver insufficiency can only be managed by liver transplantation Ref: Sabiston 20th edition Pgno : 1436", "cop": 3, "opa": "Sclerotherapy", "opb": "Conservative", "opc": "Ohotopic liver transplantation", "opd": "Shunt surgery", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "a9b31f0a-b209-4fde-a915-ac5d9453d40e", "choice_type": "single"} {"question": "Length of the cailaginous pa of \"Eustachian tube\"", "exp": "The external auditory meatus is 4 cm long and conducts sound waves from the auricle to the tympanic membrane. The framework of the anterior and medial two-thirds of the meatus is elastic cailage (measures 25 mm in length), and the posterior and lateral one third is bony, formed by the tympanic plate (measures 12 mm in length). The sensory nerve supply of the lining skin is derived from the auriculotemporal nerve and the auricular branch of the vagus nerve.The lymph drainage is to the superficial parotid, mastoid, and superficial cervical lymph nodes.", "cop": 3, "opa": "15 mm", "opb": "20 mm", "opc": "25 mm", "opd": "30 mm", "subject_name": "Anatomy", "topic_name": null, "id": "25ef8862-6650-495c-bdc0-c7cde62500d2", "choice_type": "single"} {"question": "Meiosis occurs in human males in", "exp": "Human embryology; Inderbir Singh; Tenth editionIn males, meiosis occurs in seminiferous tubules", "cop": 2, "opa": "Epididymis", "opb": "Seminiferous tubules", "opc": "Vas deferens", "opd": "Seminal vesicles", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "909dd52b-e9a3-4c93-9896-9b38d0762841", "choice_type": "single"} {"question": "Joint between sphenoid & vomer is", "exp": "Schindylesis is that form of aiculation in which a thin plate of bone is received into a cleft or fissure formed by the separation of two lamina in another bone, as in the aiculation of the rostrum of the sphenoid and perpendicular plate of the ethmoid with the vomer, or in the reception of the latter in the fissure between the maxilla and between the palatine bones. Ref: Henry Gray. Anatomy of the Human Body.", "cop": 4, "opa": "Gomphosis", "opb": "Syndesmosis", "opc": "Symphysis", "opd": "Schindylesis", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "290bbb05-584f-4fb7-bed1-24606b756eb8", "choice_type": "single"} {"question": "Thyroid carcinoma with pulsatile vascular skeletal metastasis is", "exp": "Pulsatile secondaries are seen in: Follicular carcinoma Thyroid Renal cell carcinoma ref - Srb's manual of surgery 5e p481", "cop": 3, "opa": "Medullary", "opb": "Anaplastic", "opc": "Follicular", "opd": "Papillary", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "a2ec9411-f4d8-475c-9fb3-412466712eb4", "choice_type": "single"} {"question": "In hydatidiform mole, blood cells does not develop because of defect in", "exp": "As organs form, a process called organogenesis, mesoderm interacts with endoderm and ectoderm to give rise to the digestive tract, the hea and skeletal muscles, red blood cells, and the tubules of the kidneys, as well as a type of connective tissue called mesenchyme. Ref:Human embryology Inderber singh", "cop": 2, "opa": "Primary ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Trophoblast", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a7dd554a-539e-4ab0-8697-fd5b639156af", "choice_type": "single"} {"question": "Steriocilia of hair cells are embedded in", "exp": null, "cop": 3, "opa": "Tympanic membrane", "opb": "Basilar membrane", "opc": "Tectorial membrane", "opd": "Reisner's membrane", "subject_name": "Anatomy", "topic_name": null, "id": "7434d3f3-2e91-438b-a583-582c113d4f6a", "choice_type": "single"} {"question": "Acute osteomyelitis of long bones commonly affects the", "exp": "Metaphysis of long bones is the earliest and most common site involved in osteomyelitis. x ray showing acute osteomyliyis of long bones ref : maheswari 9th ed", "cop": 3, "opa": "Epiphysis", "opb": "Diaphysis", "opc": "Metaphysis", "opd": "Aicular surfaces", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "08ae79ff-7fd7-4cd4-8023-8b799ffd1ab7", "choice_type": "single"} {"question": "Cutaneous nerve supply of region marked X", "exp": "1st web space is supplied by Deep peroneal nerve", "cop": 2, "opa": "Superficial peroneal nerve", "opb": "Deep peroneal nerve", "opc": "Medial plantar nerve", "opd": "Saphenous nerve", "subject_name": "Anatomy", "topic_name": null, "id": "93b75cf9-bae4-4205-9fd3-ac0999ee8376", "choice_type": "single"} {"question": "Ture about Mafucci syndrome is", "exp": "Maffucci syndrome is multiple Enchondromas assosciated with soft tissue Hemangioma and thrombophlebitis MAFUCCI&;S SYNDROME : * Maffucci syndrome is a congenital non hereditary mesodermal dysplasia characterised by multiple enchondromas with soft-tissue cavernous haemangiomas. * Imaging findings are multiple enchondromas seen associated with soft tissue swelling and phleboliths. * Enchondromas degenerate into chondrosarcomas in 15-51% of cases and soft-tissue haemangiomas to vascular sarcomas in 3-5%. Refer ohopedic pathology by Vincent PG p 401", "cop": 2, "opa": "Multiple osteochondroma", "opb": "Multiple Enchondroma with Hemangioma", "opc": "Multiple osteochindroma with soft tissue Hemangioma", "opd": "Multiple Hemangioma", "subject_name": "Anatomy", "topic_name": null, "id": "e46351dd-0ee8-4eb8-a981-5d6fd1143c5e", "choice_type": "single"} {"question": "The Glossopharyngeal nerve supplies the posterior pa of the tongue because it develops from the", "exp": "D i.e. Hypobranchial eminence- Tongue muscles originate from myoblast of occipital somitesQ. Thus tongue musculature is innervated by hypoglossal nerve.- Glossopharyngeal (9th) nerve supplies posterior (1/3) pa of tongue because it develops from hypobrachial eminence (copula)Q.Parathyroid glands develop from 4th (superior) & 3rd (inferior para thyroid glands) pharyngeal endodermal pouchQ.", "cop": 4, "opa": "Hyoid arch", "opb": "Tuberculum impar", "opc": "Mandibular arch", "opd": "Hypobranchial eminence", "subject_name": "Anatomy", "topic_name": null, "id": "e16d161d-823a-4ed5-9a28-9027f27d5bfd", "choice_type": "single"} {"question": "Bronchial adenoma commonly present as", "exp": "Bronchial adenoma are hypervascular and can bleed profusely. Other causes chronic cough,oobstruction with atelectasis,lobar collapse, pneumonitis, and abscess formation Ref Harrison 19th edition pg 1676", "cop": 1, "opa": "Recurrent haemoptysis", "opb": "Cough", "opc": "Dysponea", "opd": "Chest pain", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "085cc67d-4e28-40bd-a8f8-f6408d49fb02", "choice_type": "single"} {"question": "Best marker for iron deficiency is", "exp": "Ref Harrison 19 th ed pg 627-628 The serum ferritin level is a better indicator of iron overload than the marrow iron stain. However, in addition to storage iron, the marrow iron stain provides information about the effective delivery of iron to develop- ing erythroblasts.", "cop": 2, "opa": "Serum iron", "opb": "Serum ferritin", "opc": "Total iron binding capacity", "opd": "Transferrin saturation", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "72e8814f-7b9e-43b7-a0f5-ca05b094423b", "choice_type": "single"} {"question": "Resting membrane potential is determined by", "exp": "Resting membrane potential CellsResting membrane potentialSkeletal muscle -90 mVSmooth muscle -50 to -75 mVCardiac muscle -85 to -95 mVNerve fibre -70 mVRods -40 mVInner ear cell-60 mVResting Membrane Potential is due to K+ Resting membrane Potential is close to the isoelectric potential of Cl-IPSP is due to Cl- influxEPSP is due to the K+ influx (Refer: Ganong's Review of Medical Physiology 24thedition, pg no: 87-89)", "cop": 2, "opa": "Na+", "opb": "K+", "opc": "CI-", "opd": "Mg++", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "f6c6cc1a-d0d5-4da9-80d1-99a9f230d9db", "choice_type": "single"} {"question": "Hea beat in conceptus can be detected earliest by", "exp": "The CVS is the earliest system to become functional is human. Hea begins to beat in the fouh week of development( Day 22 ).", "cop": 1, "opa": "4-6 weeks", "opb": "12-14 weeks", "opc": "14-16 weeks", "opd": "21-24 weeks", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "b8bbd9e5-2386-420f-962f-d0184051b0c1", "choice_type": "single"} {"question": "The amino acid that acts as a precursor in the production of urea is", "exp": "(Refer: Harper's Illustrated Biochemistry, 26th edition, pg no: 265)", "cop": 1, "opa": "Arginine", "opb": "Aspaic acid", "opc": "Ornithine", "opd": "Glutamate", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e5b121a0-3de4-460f-a5c5-6ccbb891e970", "choice_type": "single"} {"question": "Skin over the angle of mandible is supplied by", "exp": "Ans. d (Great auricular nerve) (Ref. BDC Vol. Ill 4th ed. 57)The great auricular nerve originates from the cervical plexus, composed of branches of spinal nerves C2 and C3. It provides sensory innervation for the skin over angle of mandible (parotid area) and mastoid process, and both surfaces of the outer ear.INNERVATION OF THE SKIN OF FACE# Innervation of the skin is mainly through the three branches of the trigeminal nerve (CN V).# Some skin over the angle of the mandible and anterior and posterior of the auricle is supplied by the great auricular nerve from the cervical plexus.# Some cutaneous branches of the auricular branch of the facial nerve also supply skin on both sides of the auricle.# The trigeminal nerve is the general sensory nerve to the head, particularly the face, and is the motor nerve to the muscles of mastication.", "cop": 4, "opa": "Auriculotemporal nerve", "opb": "Lesser occipital nerve", "opc": "Infraorbital nerve", "opd": "Great auricular nerve", "subject_name": "Anatomy", "topic_name": "Scalp Face & Temple", "id": "c6b9d08a-b4f0-42e9-9fd4-476a7bc1503b", "choice_type": "single"} {"question": "Sensory nerve supply to angle of jaw is through", "exp": "The trigeminal nerve through its three branches is the chief sensory nerve of the face. The skin over the angle of the jaw and over the parotid gland is supplied by the great auricular nerve (C2,C3)", "cop": 1, "opa": "Great auricular nerve", "opb": "Buccal branches of facial nerve", "opc": "Lesser petrosal nerve", "opd": "Auriculotemporal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "7a2a19d1-0ac7-4b9b-973e-bba97387208e", "choice_type": "single"} {"question": "Thymus develops from", "exp": "Pharyngeal pouchDerivativesDorsal ends of I and II pouches form --Tubotympanic recessThe proximal pa of tubotympanic recess gives rise to auditory tube.Distal pa gives rise to tympanic cavity and mastoid antrum. Mastoid cellsdevelop at about 2 years of ageVentral pa of II pharyngeal pouchEpithelium covering the palatine tonsil and tonsillar crypts, lymphoid tissueis mesodermal in originIII Pharyngeal pouchThymus and inferior parathyroid gland or parathyroid III.IV Pharyngeal pouchSuperior parathyroid or parathyroid IVV Pharyngeal pouch (ultimobranchial body)Parafollicular or 'C' cells of the thyroid glandRef: Chaurasia; Volume 3; 6th edition; Page no: 30", "cop": 3, "opa": "I Pharyngeal pouch", "opb": "II Pharyngeal pouch", "opc": "III Pharyngeal pouch", "opd": "IV Pharyngeal pouch", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "fd433eae-60d3-40b6-a97d-d2ca1a34c23a", "choice_type": "single"} {"question": "Least chances of cord prolapse are seen with", "exp": "Maximum chances of cord prolapse seen in breech are in footling where as min chances in frank frank breech", "cop": 1, "opa": "Frank breech", "opb": "Complete breech", "opc": "Footling", "opd": "Knee", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "6f5572d0-f3da-407c-8bb2-94dae37236b0", "choice_type": "single"} {"question": "Olfactory epithelium is", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:225Olfactory epitheliumThe olfactory epithelium is pseudo stratified it imuch thicker than the epithelium lining the respiratory mucosa", "cop": 4, "opa": "Squamous Keratinised", "opb": "Squamous non keratinised", "opc": "Striated columnar", "opd": "Psudostratified", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7d60ecfd-8843-44e9-ba8c-e788aabdc526", "choice_type": "single"} {"question": "Gerlach tonsil is", "exp": "A collection of lymphoid tissue is present in the nasopharynx, behind the tubal opening. It is called the tubal tonsil, also known as Gerlach tonsil. It is continuous with the lateral pa of the pharyngeal tonsil. In Waldeyer's lymphatic ring, the most impoant aggregations are the right and left palatine tonsils. Posteriorly and above there is the pharyngeal tonsil; laterally and above there are the tubal tonsils, and inferiorly there is the lingual tonsil over the posterior pa of the dorsum of the tongue. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 3, "opa": "Palatine tonsil", "opb": "Lingual tonsil", "opc": "Tubal tonsil", "opd": "Nasopharyngeal tonsil", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "908465f6-66c2-4a96-b3d2-456e3aae25cb", "choice_type": "single"} {"question": "Sternohyoid is supplied by", "exp": "The ansa cervicalis or ansa hypoglossal is a thin nerve loop that lies embedded in the anterior wall of the carotid sheath over the lower pa of the larynx.It supplies the infrahyoid muscles. Distribution Superior root:To the superior belly of the omohyoid. Ansa cervicalis:To the sternohyoid,the sternothyroid and the inferior belly of the omohyoid. The throhyoid and geniohyoid are supplied by seperate branches from the first cervical nerve through the hypoglossal nerve. REF.BDC VOL.3,FIFTH EDITION", "cop": 2, "opa": "CI through hyoid glossal nerve", "opb": "Ansa cervicalis", "opc": "Glossopharyngeal nerve", "opd": "Hypoglossal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "8dc79a84-ed83-4e3c-aafc-76871e9501a5", "choice_type": "single"} {"question": "Solitary bone cyst is most common in the", "exp": "Simple bone cysts commonly occurs at Metaphysis of long bones Most common site is proximal humerus, followed by proximal femur SIMPLE BONY CYST : ACTIVE : Develop in patients under 10 years of age * Cyst arises adjacent to growth plate & may grow to fill most of metaphysis Bone may be slightly expanded within coical shell * May cause pathologic fracture PASSIVE : Passive cysts patients are usually over 12 years of age &; become increasingly separated from gmwth plate (more ) than 1-2 an) have thicker bony wall than active lesions may show evidence of healing or ossification less likely to result in fracture CAUSES : * The cause of a unicameral bone cyst remains unknown. Theories have been proposed but none have been definitively proven. * One of these theories is that the cysts result from a disorder of the growth plate. * Another is that the cysts result from problems with circulation that are caused by a developmental anomaly in the veins of the affected bone. * The role trauma plays in the development of these cysts is unknown. Symptoms: * Unless there has been a fracture, bone cysts arc without symptoms. * They may occasionally be discovered by chance on x-rays obtained for other reasons. * There is no mass or tenderness unless there is a fracture. * There may be an abnormal angulation of the limb secondary to the fracture or shoening of the limb if the adjacent growth plate is involved. Location lesion appears to arise from the growth plate & in early stages, lesion is lies adjacent to growth plate; typically the simple bone cyst will have a central location, whereas an ABC will have a slightly eccentric location; predilection for the metaphysis of long bones; - proximal humerus (SO% of cases) - proximal tibia - proximal femur (40%) - foot:Calcaneal Bone Cysts Radiographs show a central, well marginated & symmetric radiolucent defect in metaphysis metaphyseal bone does not remodel normally metaphysis is broader than normally seen but not broader than with width of epiphyseal plate thin rim of non reative bone borders the unicameral bone cyst Refer Maheshwari 9th/e p 248", "cop": 1, "opa": "Upper end of humerus", "opb": "Lower end humerus", "opc": "Upper end of tibia", "opd": "Lower end of femur", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "5b526a89-f0c8-420c-a2da-15275fd8fde8", "choice_type": "single"} {"question": "Most common symptom of chronic pancreatitis is", "exp": "Clinical features of Chronic pancreatitis Classical triad : DM+ Pancreatic calcification + Steatorrhea(DPS) Abdominal pain is the primary manifestation and most common symptom of CP Intensity, frequency & duration of pain gradually increase with worsening disease Pancreatic inflammation and fibrosis decrease the number & function of acinar cells At least 90% of the gland needs to be dysfunctional before steatorrhoea, diarrhea and other symptoms of malabsorption develop Exocrine insufficiency occurs in 80-90% of patients with long standing CP Diabetes is developed in 40-80% of patients, typically occurs many years after the onset of abdominal pain and pancreatic Exocrine insufficiency Ref: Sabiston 20th edition Pgno :1531", "cop": 1, "opa": "Abdominal pain", "opb": "Cachexia", "opc": "Weight loss", "opd": "Steatorrhoea", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "703be3eb-0865-44c4-9be5-ce2b9bc83616", "choice_type": "single"} {"question": "Bile ductopenia seen in", "exp": "Ductopenia Ductopenia refers to a reduction in the number of ducts in an organ. It is the histological hallmark of vanishing bile duct syndrome (typically <0.5 bile ducts per poal triad). The most common cause of ductopenia is primary biliary cholangitis. Other causes failing liver transplant Hodgkin's lymphoma graft-versus-host disease (GVHD) sarcoid cytomegalovirus infection, HIV medication toxicity. Ref: Harrison's 19th edition Pgno :2027-2028", "cop": 1, "opa": "GVHD", "opb": "Alcoholic hepatitis", "opc": "Autoimmune hepatitis", "opd": "Cirrhosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b0bae284-e5dc-4d80-97c3-59cfe72e8b4d", "choice_type": "single"} {"question": "Chronic granulomatous inflammation in upper lid (painless swelling);", "exp": "Chalazion is a chronic granulomatous inflammation of the meibomian gland. Chalazion (tarsal cyst/meibomian cyst) Presents as painless swelling of eye lid More common in adults than children Treatment Incision and curettage Intralesional injection of triamcinolone acetate. CHALAZION", "cop": 3, "opa": "Internal Hordeolum", "opb": "External hordeolum", "opc": "Chalazion", "opd": "Trachoma", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "969e61ff-ff55-41d2-8d3c-445d2e6c0226", "choice_type": "single"} {"question": "McEwan's pupil is seen in", "exp": "Stage of coma in ethyl alcohol poisoning The person may go to a stage of coma at a blood alcohol concentration of more than 300mg%. There will be steorous breathing. The pulse is rapid and temperature is subnormal. Pupils remaining constricted. On slapping or pinching on the face, causes pupils to dilate and gradually return to constriction (McEwan's pupils) ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 437", "cop": 3, "opa": "Opioid poisoning", "opb": "Mercury poisoning", "opc": "Alcohol poisoning", "opd": "Chronic lead poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "6e16f369-7335-48ed-bce2-d84dc0921231", "choice_type": "single"} {"question": "Base of femoral triangle is formed by", "exp": "Base of femoral triangle is inguinal ligament which is aponeurosis of external oblique muscle. Medial border of adductor longus forms the medial boundary. Medial border of Saorius forms the lateral boundary. Floor is formed by adductor longus,pectineus and iliacus. Femoral aery, femoral vein and lymphatics are involved in femoral sheath.", "cop": 1, "opa": "Inguinal ligament", "opb": "Medial border of saorius", "opc": "Medial borer of adductor longus", "opd": "Iliacus", "subject_name": "Anatomy", "topic_name": "Abdominal wall ,Inguinal and Femoral region", "id": "58af5a04-c7a9-48fd-addb-8c4d9788d304", "choice_type": "single"} {"question": "Spinal cord ends at the level of", "exp": "(A) L1 vertebra # Spinal cord:> At birth, spinal cord terminates at lower border of L2.> In Adults, it extends from the level of the upper border of the atlas to the lower border of vertebra L1, or the upper border of vertebra L2.> Spinal cord is about 45 cm long.> Spinal cord extends from the level of the upper border of the atlas to the lower border of L1 vertebra or the upper border of L2 vertebra. It is about 45 cm long.> The lower end is conical and is called conus medullaris.> The apex of the conus is continued down as the filum terminate> There are 31 pairs of spinal nerves.", "cop": 1, "opa": "LI vertebra", "opb": "L2 vertebra", "opc": "SI vertebra", "opd": "L3 vertebra", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "3f85394c-2823-426b-9d0b-727c9772cdd7", "choice_type": "single"} {"question": "The relation of common bile duct", "exp": "The anterior border of the liver is lifted upwards. Gallbladder with Longitudinal section, pancreas, and duodenum with frontal one. Intrahepatic ducts and stomach in transparency. It is formed by the union of the common hepatic duct and the cystic duct (from the gallbladder). ref - BDC 6e vol2 pg289", "cop": 2, "opa": "Lies of poal vein", "opb": "Lies right to hepatic aery", "opc": "Lies left to hepatic aery", "opd": "Lies posterior to hepatic aery and poal vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "153b97c3-6443-41ed-a438-2d2709fd6bce", "choice_type": "single"} {"question": "bulimia nervosa is assosiated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 2, "opa": "metabolic syndrome", "opb": "russels sign", "opc": "obesity", "opd": "verguath fold", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "8223d0e2-4883-4114-97d7-90c9a911db40", "choice_type": "single"} {"question": "Sphincter of Oddi consists of", "exp": "The sphincter of Oddi is a muscular valve that controls the flow of digestive juices through the ampulla of vater into the second pa of the duodenum. It is named after ruggero oddi. Ref - BDC 6e vol2 pg259 , britannica.com", "cop": 2, "opa": "2 sphincters", "opb": "3 sphincters", "opc": "4 sphincters", "opd": "5 sphincters", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "f28603ee-fea9-4207-8afc-f5bb0bd167e8", "choice_type": "single"} {"question": "A 20 Yr old male presented with repeated episodes of hemetemesis. There is no history of jaundice or liver decompensation. On examination the significant findings include splenomegaly (8cms below costal margin), and presence of esophageal varices. There is no ascites or peptic ulceration. The liver function tests are normal. The most likely diagnosis is", "exp": "Non cirrhotic poal fibrosis Condition of liver characterized by widespread fibrosis of liver(mainly poal, subcapsular and rarely perisinusoidal) causing wide variation in normal architecture There is no true cirrhosis Etiology Chronic ingestion of arsenic, copper, vinyl chloride Clinical features Youny age patient with features of poal hypeension with conspicuous absence of liver cell failure Patient are usually on 2nd or 3rd decade Onset of symptoms is gradual Most common presenting symptom is GI bleed (90% cases) Splenomegaly Jaundice, Hepatomegaly, ascites and stigmata of liver cell failure are uncommon Diagnosis Site of block is smaller branches (3rd or 4th order branches) Ultrasound shows normal splenopoal axis. Withered tree appearance and peripoal fibrosis is seen in NCPF Ref: Blumga 5th edition Pgno : 1099-1105", "cop": 2, "opa": "Extra hepatic poal venous obstruction", "opb": "Non-cirrhotic poal fibrosis", "opc": "Cirrhosis", "opd": "Hepatic venous outflow tract obstruction", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "98f7241b-16ba-4011-acd6-728a15ebbf47", "choice_type": "single"} {"question": "Thiamine acts as a cofactor in", "exp": "Thiamine as a cofactor in ReactionsEnzymesPyruvate - Acetyl CoAPyruvate dehydrogenasea-ketoglutarate - Succinyl CoAa-ketoglutarate dehydrogenaseErythrose-4-PO4 + Xylulose-5-PO4 - Fructose-6-PO4 + Glyceraldehyde-3-PO4TransketolaseBranched-chain amino acids - Branched chain keto acidsBranched-chain amino acid dehydrogenase(Refer: DM Vasudevan, Textbook of Biochemistry, 7th edition, pg no: 478)", "cop": 4, "opa": "Pyruvate to oxalate", "opb": "Malonate to oxaloacetate", "opc": "Succinate to fumarate", "opd": "Pyruvate to acetyl CoA", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "831f611c-8c9b-4ab6-a15a-782d4b0267bf", "choice_type": "single"} {"question": "Middle aged man presents with complaints of weakness, fatigue and hyperpigmentation. On examination hepatomegaly and Hypoglycemia are present. Diagnosis", "exp": "Manifestation of Hemochromatosis Liver : Hepatomegaly, cirrhosis, HCC Pancreas : Diabetes mellitus Hea: CHF, cardiomyopathy Skin: Hyperpigmentation(bronzing of skin) Joints : Ahropathy Hypogonadism Ref:Harrison's 19th edition Pgno :2516", "cop": 2, "opa": "Addison's disease", "opb": "Hemochromatosis", "opc": "IDDM", "opd": "Cushing's syndrome", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fb52d2ad-1e56-4244-8a5d-bd9fd2cdb698", "choice_type": "single"} {"question": "Ansa nephroni is lined by", "exp": "Ansa nephroni is lined by simple squamous epithelium", "cop": 2, "opa": "Columnar epithelium", "opb": "Squamous epithelium", "opc": "Cuboidal adn columnar epithelium", "opd": "Cuboidal epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2109fed3-d171-4b7a-b0e3-dd6fac87c6fc", "choice_type": "single"} {"question": "In a female child at bih oocyte is in a stage of", "exp": "B. i.e. Prophase 1st meiotic", "cop": 2, "opa": "Anaphase 2nd meiotic", "opb": "Prophase 1st meiotic", "opc": "Oogony", "opd": "Maturation", "subject_name": "Anatomy", "topic_name": null, "id": "a7707ec3-bc1f-4e43-8874-b2453342ca35", "choice_type": "single"} {"question": "Cyclosporine is an", "exp": "Ref Bailey and love 27/e p1538", "cop": 4, "opa": "Antioxidant", "opb": "Immunity booster", "opc": "Antibiotics", "opd": "Immunosuppressant", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c02d44f7-bcff-4062-97de-f6e850f57b61", "choice_type": "single"} {"question": "In HCC", "exp": "Clinical features of HCC Vascular bruit (25%) GI bleed (10%) Tumor rupture (2-5%) Jaundice due to biliary obstruction (10%) Paraneoplastic syndrome (<5%) Ref:Sabiston 20th edition Pgno : 1456-1463", "cop": 3, "opa": "Aerial bruit is present in 80% of cases", "opb": "Two-third patients presents with signs of liver disease", "opc": "Hemoperitoneum in 7% of cases", "opd": "Percutaneous biopsy is mandatory for diagnosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3b339c0c-d2d4-4857-b657-476ce9869612", "choice_type": "single"} {"question": "Study light is caused by", "exp": "Sterlite and secondary leukemias are distinguish adverse effects of alkylation agents", "cop": 2, "opa": "Vinca alkaloids", "opb": "Alkylation agents", "opc": "Antimetabolite", "opd": "Antinomycin D", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "36a7f94d-3944-4eab-97ac-0a9da2e33232", "choice_type": "single"} {"question": "Poosystemic shunt is not seen in", "exp": "Poosystemic shunt is not seen in spleen. Poosystemic shunt is abnormal connection between hepatic poal vein and the systemic circulation. It can be either congenital or acquired condition. A poosystemic shunt (PSS) is an abnormal connection between the poal vascular system and systemic circulation. Blood from the abdominal organs which should be drained by the poal vein into the liver is instead shunted to the systemic circulation by the PSS. Ref - sciencedirect.com", "cop": 2, "opa": "Liver", "opb": "Spleen", "opc": "Anorectum", "opd": "Gastro Esophageal", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e2677ee5-f11d-4eb8-9c04-c950835545ed", "choice_type": "single"} {"question": "The pleura that covers the surface of the lungs is the", "exp": "C: The visceral pleura covers the surface of the lung.\nA, B: The pleural cavity, between the parietal and visceral pleurae, is filled with a small volume of pleural fluid produced by the pleural membranes.\nD: The parietal pleura lines the walls of the thorax, diaphragm, and mediastinum", "cop": 3, "opa": "Pleural Cavity", "opb": "Pleural Fluid", "opc": "Visceral Pleura", "opd": "Parietal Pleura", "subject_name": "Anatomy", "topic_name": null, "id": "a7ae2b47-90b3-4bd3-873f-28a9d6a1dfa6", "choice_type": "single"} {"question": "Submandibular Acinar Cells secrete", "exp": "Lysozyme, an enzyme with antibacterial activity, is produced primarily by the Submandibular Salivary Gland Acinar Cells", "cop": 2, "opa": "Glucagon", "opb": "Lysozyme", "opc": "Insulin", "opd": "Plasma proteins", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "b4cdc059-52e6-4b5d-9472-a87cdd320529", "choice_type": "single"} {"question": "The pa of internal capsule associated with acoustic radiation is", "exp": ".", "cop": 3, "opa": "Genu", "opb": "Anterior limb", "opc": "Sublentiform", "opd": "Retrolentiform", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c9215fdd-9bde-4c46-abf2-e89286fc21fe", "choice_type": "single"} {"question": "Largest opening in the Right atrium", "exp": "Right Atrioventricular Orifice Blood passes out of the right atrium through the right atrioventricular or tricuspid orifice and goes to the right ventricle. The tricuspid orifice is guarded by the tricuspid valve which maintains unidirectional flow of bloodReference: Vishram Singh Anatomy; 2nd edition; Page no: 265", "cop": 3, "opa": "Superior Venacava", "opb": "Inferior Venacava", "opc": "Right Atrioventricular Orfice", "opd": "Coronary SInus", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "dd039c6c-62b5-480c-8d5a-64449ed69647", "choice_type": "single"} {"question": "Lipid in the tissue is detected by", "exp": "Ref Bancroft histology 6/e p53 Oil Red O is a lysochrome diazo dye used for staining of neutral triglycerides and lipids on frozen sections and some lipoproteins on paraffin sections. It has the appearance of a red powder with maximum absorption at 518 nm", "cop": 3, "opa": "PAS", "opb": "Myeloperoxidase", "opc": "Oil Red O", "opd": "Mucicarmine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f27ecdca-292a-410f-8492-e58a05f6d765", "choice_type": "single"} {"question": "Benedict's hand is due to injury to", "exp": "BENEDICTION ATTITUDE:-Injury to median nerve at elbow Causes:- supracondylar fractures of humerus, application of tight tourniquet during venepuncture, entrapment of the nerve between two heads of pronator teres.When patient tries to make fist, the index and middle fingers remain straight, due to paralysis of both superficial and deep flexors of fingers.The ring and little fingers can be kept in flexed position due to intact nerve supply of medial half of the FDP.{Reference:Vishram Singh, page no.195}", "cop": 2, "opa": "Ulnar nerve", "opb": "Median nerve", "opc": "Axillary nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "9a479b55-d89a-4756-a4f7-d12a3cba8dda", "choice_type": "single"} {"question": "Ochronosis is seen in", "exp": "Ochronosis It is the greenish black discoloration of tissues, mainly cailages, fibrous tissues, and sclera. It is seen in alkaptonuria. It can also occur due to exposure to various substances like phenol, trinitrophenol, resorcinol, hydroquinone, benzene, picric acid, mercurry or antimalarials. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 415", "cop": 1, "opa": "Phenol poisoning", "opb": "Oxalic acid poisoning", "opc": "Nitric acid poisoning", "opd": "Sulphuric acid poisoning", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e06cd9a3-af25-4a20-aaed-d77e88126691", "choice_type": "single"} {"question": "Lines of Blaschko&;s are along", "exp": "Blaschko&;s lines, are lines of normal cell development in the skin. These lines are invisible under normal conditions.", "cop": 3, "opa": "Lymphatics", "opb": "Nervs", "opc": "Developmental", "opd": "Blood vessels", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2d7752b3-6526-4bba-90a1-b7862767573b", "choice_type": "single"} {"question": "Fairy 23 year old pregnant female having severe sensitivity to amoxicillin drug used to treat Gonorrhea in a single dose should be", "exp": "Ref-Katzung 10/e p761,762 Ceftriaxone is contraindicated in patients having severe allergy to penicillins. Tetracvclines are not etfective against gonorrhoea. Although ciprotloxacin is etfective as a single dose treatment ot gonorrhoea but it is contraindicated in pregnancy. Spectinomycin can be given as single dose treatment of PPNG.", "cop": 4, "opa": "Ceftriaxone", "opb": "Tetracycline", "opc": "Ciprofloxacin", "opd": "Spectinomycin", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "a8e6c3b4-3f7f-4ab0-bb7a-75aa0cd3f6f0", "choice_type": "single"} {"question": "This arrangement of myofibrils are found in", "exp": "Refer robbins 9/e 569 Hyperophic cardiomyopathy (HCM) is a disease in which the hea muscle (myocardium) becomes abnormally thick (hyperophied). The thickened hea muscle can make it harder for the hea to pump blood. Hyperophic cardiomyopathy often goes undiagnosed because many people with the disease have few, if any, symptoms and can lead normal lives with no significant problems. However, in a small number of people with HCM, the thickened hea muscle can cause shoness of breath, chest pain or problems in the hea's electrical system, resulting in life-threatening abnormal hea rhythms (arrhythmias).", "cop": 4, "opa": "Dilated cardiomyopathy", "opb": "Constrictive cardiomyopathy", "opc": "Fibroelastic cardiomyopathy", "opd": "Hyperophic cardiomyopathy", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "6fd68fbf-c7c2-45b0-8eea-fab91229c93c", "choice_type": "single"} {"question": "Investigation of choice for diagnosis of Epilepsy is", "exp": "All patients who have a possible seizure disorder should be evaluated with an EEG as soon as possible. The EEG is most useful in evaluating patients with suspected epilepsy. The presence of electrographic seizure activity - i.e., abnormal, repetitive, rhythmic activity having an abrupt onset and termination and a characteristic evolution - clearly establishes the diagnosis.", "cop": 1, "opa": "EEG", "opb": "CT scan", "opc": "MRI", "opd": "CSF investigations", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b2b8369f-13db-48ca-ae15-42a2c3cb4e0a", "choice_type": "single"} {"question": "Number of veebrae in veebral column", "exp": "There are total thiy-three veebrae, upper twenty-four are aiculating and separated from each other by interveebral discs, seven cervical veebrae, twelve thoracic veebrae and five lumbar veebrae. The lower nine are fused, five in the sacrum and four in the coccyx.", "cop": 4, "opa": "25", "opb": "27", "opc": "29", "opd": "33", "subject_name": "Anatomy", "topic_name": "Back region", "id": "f84e00a7-2f4c-4ed5-825b-0b0400b479c7", "choice_type": "single"} {"question": "The length of the feeding tube to be inseed for transpyloric feeding is measured from the tip of", "exp": "The feeding tube length can be measured by following the normal route for tube i.e. Nasal ala - to ear lobe - to epigastium Since the distance between the nasal ala and ear lobe is almost equal to the distance between the epigastrium and umbilicus, the length can be measured from ear lobe to umbilicus.", "cop": 2, "opa": "Nose to the umblicus", "opb": "Ear lobe to the umblicus", "opc": "Nose to the pelvis", "opd": "Ear lobe to the pelvis", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "40e51276-aaf1-4cc8-8141-3905da5cbe9b", "choice_type": "single"} {"question": "Serotonin can be synthesized from", "exp": "In bacteria that synthesize tryptophan, high cellular levels of this amino acid activate a repressor protein, which binds to the trpoperon. Binding of this repressor to the tryptophan operon prevents transcription of downstream DNA that codes for the enzymes involved in the biosynthesis of tryptophan Refer kDT 7/e p170", "cop": 1, "opa": "Tryptophan", "opb": "Trypsin", "opc": "Dopa", "opd": "Epinephrine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c74bf202-7049-4f68-aefd-f7c2a063981d", "choice_type": "single"} {"question": "Intermediate filaments in glial cells are", "exp": "Intermediate filaments are used as tumor markers GFAP is the intermediate filament present in glial cells, they are used to indicate astrocytoma Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:8,9,14", "cop": 3, "opa": "Keratin", "opb": "Desnin", "opc": "GFAP", "opd": "Bone", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "96259ab0-3fa4-45db-bc22-19c0dbf315da", "choice_type": "single"} {"question": "Inguinal ligament forms the boundaries of", "exp": "INGUINAL LIGAMENT:- Extends from anterior superior iliac spine to pubic tubercle. Forms boundaries of femoral triangle and Hesselbach&;s triangle. FEMORAL TRIANGLE:- Triangular depression on front of the upper one third of the thigh immediately below the inguinal ligament. BOUNDARIES :- 1. Laterally: medial border of saorius. 2. Medially: medial border of adductor longus. 3. Base: inguinal ligament. 4. Apex:directed downwards.formed by the point where the medial and lateral boundaries cross.apex is continuous with the adductor canal. 5. Roof: skin,superficial fascia and deep fascia.Superficial fascia contains superficial inguinal lymph nodes,femoral branch of genitofemoral nerve,branches of ilioinguinal nerve,superficial branches of the femoral aery with accompanying veins and the upper pa of the great saphenous vein. 6. Floor: medially by adductor longus and pectineus,and laterally by the psoas major and iliacus. CONTENTS:- 1. Femoral aery and its branches.- Superficial branches-superficial external pudendal Superficial epigastric Superficial circumflex iliac Deep branches-profunda femoris, muscular branches and deep external pudendal 2. Femoral vein and its tributaries 3. Femoral sheath 4. Femoral nerve 5. Nerve to pectineus 6. Femoral branch of genitofemoral nerve. 7. Lateral cutaneous nerve of thigh. 8. Deep inguinal lymph nodes. Vein is medial to aery (base) Vein posteromedial to aery (apex) HESEELBACH&;S TRIANGLE:- Boundaries- 1. Medially-Lateral border of rectus abdominis 2. Laterally- inferior epigastric aery. 3. Base - inguinal ligament. {Reference:BDC 6E pg no. 45}", "cop": 2, "opa": "Calots triangle", "opb": "Hesselbach's triangle", "opc": "Triangle of doom", "opd": "Triangle of pain", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "2c736762-d564-4d6d-b840-d246b6657555", "choice_type": "single"} {"question": "In spinal groove, radial nerve is accompanied by", "exp": "radial nerve- At the beginning of the brachial aery, the radial nerve lies posterior to the aery. Soon the nerve leaves the aery, by entering the radial (spiral) groov on the back of the arm where it is accompanied by th profunda brachii aery. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no. 96 fig. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no.74 ( fig. no. 6.11 )", "cop": 3, "opa": "Median nerve", "opb": "Axillary aery", "opc": "Profunda brachii aery", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "d91c87a7-4499-4746-9d16-473fa6b0416e", "choice_type": "single"} {"question": "JG cells (juxta glomerular apparatus) are", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:313Juxtaglomerular cells the muscle cells in the wall of the afferent aerioles are modified.they are large and rounded(epithelium)and have spherical nuclei. their cytoplasm contains granules that can be stained with special methods. these are called juxtaglomerular cells", "cop": 2, "opa": "Macula densa", "opb": "Smooth muscullar cells of afferent aeriole", "opc": "Smooth muscullar cells of efferent aeriole", "opd": "Islets of epithelial cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "babc3683-1eae-43c5-ad17-5a0ccd785340", "choice_type": "single"} {"question": "Alpha fetoprotein is a marker of", "exp": "Ref Robbins 8/e p 327; 7/e P339,9/e p869_870 AFP is Glycoprotein synthesized in fetal life by yolk sac,fetal liver,fetal GIT.It is a marker of hepatocellular carcinoma,non seminomatous germ cell tumor Of testis Elevated level of AFP Is found less regularly in carcinoma of lung,colon, pancreas IImpoant points about hepatoblastoma arising from hepatic parenchymal cells The most common tumor in Child hood A characteristic features of hepatoblastoma is frequent activation of WTN/catenin signalling pathway,by stabilizing mutation of beta catenin,contributes to the process of carcinogenesis", "cop": 1, "opa": "Hepatoblastoma", "opb": "Seminoma", "opc": "Renal cell carcinoma", "opd": "Choriocarcinoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "86988ada-6de4-4eec-ae88-d585465e6ee8", "choice_type": "single"} {"question": "Collecting pa of kidney develops from", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:285The collecting pa of the kidney is derived from a diveiculum called the Ureteric bud which arises from the lower pa of the mesonephric duct", "cop": 4, "opa": "Pronephrons", "opb": "Mesonephros", "opc": "Metanephros", "opd": "Ureteric bud", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cac6968a-d641-4ab8-bed2-dd6a1b761e2c", "choice_type": "single"} {"question": "External auditory meatus develops from", "exp": null, "cop": 1, "opa": "Dorsal part of 1st ectodermal cleft", "opb": "Dorsal part of 2nd ectodermal cleft", "opc": "Dorsal part of 3rd ectodermal cleft", "opd": "Sixth branchial arch", "subject_name": "Anatomy", "topic_name": null, "id": "b429ff48-259a-483b-b295-2a212a14ad2d", "choice_type": "single"} {"question": "VNS works by", "exp": "Vagus nerve stimulation * Electrical stimulation of left vagus nerve * Stimulation of raphe nucleus and locus cereleus * Release of norepinephrine and serotonin * Side effects * Voice alteration Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, 1075", "cop": 2, "opa": "deep brain stimulation", "opb": "vagal nerve stimulation", "opc": "magnetic stimulation", "opd": "convulsion production", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8d6bf6a6-6bf2-4b6f-bc85-abbfd8fe610d", "choice_type": "single"} {"question": "Lateral cutaneous nerve of thigh arises from", "exp": "LUMBAR PLEXUSFormed by ventral rami of LI, L2, L3, and pa of L4. These rami divide into dorsal and ventral divisions.From the ventral divisions: ilioinguinal (LI), genitofemoral (LI, L2) obturator (L2, L3, L4), accessory obturator (L3, L4) nerves.From the dorsal divisions: Lateral cutaneous nerve of thigh (L2, L3), femoral nerve (L2, L3, L4).Iliohypogastric contains fibers of both ventral and dorsal divisions (LI).Reference: Chaurasia Volume II; 7th edition; Page no: 41", "cop": 2, "opa": "Femoral Nerve", "opb": "Lumbar Plexus", "opc": "Obturator Nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "777238fd-ea3f-4497-baa3-49a3cdcb1ae7", "choice_type": "single"} {"question": "Tendon present in third extensor compament of wrist is", "exp": "6 iteofascial compaments are formed on the back of the wrist ( extensor retinaculum ). The structures passing through each ompament, from lateral to the medial side are - 1st compament - (i) Abductor pollicis longus (ii) Extensor pollicis brevis IInd compament - (i) Extensor carpi radialis longus (ii) Extensor carpi radialis brevis IIIrd compament - (i) Extensor pollicis longus IVth compament - (i) Extensor digitorum (H) Extensor indicts (iii) Posterior interosseous nerve (iv) Anterior interosseous aery Vthcomparment - (i) Extensor digiti minimi VIth compament - (i) Extensor carpi ulnaris. Ref : B D Chaurasia's Human Anatomy, Seventh edition , volume 1 , pg. no., 135", "cop": 3, "opa": "ECRL", "opb": "ECRB", "opc": "EPL", "opd": "EPB", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "d4779d6a-7e29-4ea1-b9a3-7134d68c3e0f", "choice_type": "single"} {"question": "Upper two posterior intercostal aeries arise from", "exp": "First and second posterior intercostal aeries arise from superior intercostal aery B D CHAURASIA&;S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION,Page no-219", "cop": 2, "opa": "Aoa", "opb": "Superior intercostal aery", "opc": "Internal mammary aery", "opd": "Bronchial aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ef9d1358-aee6-42d9-b6e9-e7fff613cab8", "choice_type": "single"} {"question": "Length of anal canal", "exp": "The length of the anal canal is about 4 cm (range, 3-5 cm), with two thirds of this being above the pectinate line (also known as the dentate line) and one third below the pectinate line ref - BDC 6e vol2 pg413", "cop": 4, "opa": "10 - 15 mm", "opb": "15 - 20 mm", "opc": "25 - 30 mm", "opd": "35 - 40 mm", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "287cbb38-377e-43de-b733-66732e979c53", "choice_type": "single"} {"question": "The lymphatic drainage of testes is", "exp": "Blood Supply and Lymphatic Drainage. The testis and epididymis are supplied by the testicular aery , and their veins drain into the pampiniform plexus, which forms the bulk of the spermatic cord. The veins of the pampiniform plexus often become varicose, a condition termed varicocele. Ref - BDC 6e vol2 pg224 , semantischolar.org", "cop": 3, "opa": "Inguinal lymph node", "opb": "Mesenteric lymph node", "opc": "Para-aoic lymph node", "opd": "Obturator lymph node", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "bf351f4d-8b66-46f2-a8ee-e933dedae7b5", "choice_type": "single"} {"question": "Cremaster muscle is supplied by", "exp": "Ans. a (Genital branch of genito-femoral nerve). (Ref. BD Chaurasia, Human Anatomy Vol. II 3rd ed. 172)CREMASTER# Cremaster Muscle consist of muscle fasciculi embedded in the cremasteric facia.# Fasciculi form loop that are attached laterally to inguinal ligament & medially to pubic tubercle, pubic crest, the conjoint lendon.# It is fully developed only in male.# It is supplied by Genital branch of the genitofemoral nereve (LI).# Its action is to suspend testis & can elevate it.# It also closes superficial inguinal ring by 'ball valve' mechanism when intraabdominal pressure is raised.# In UMN lesions above segment LI, Cremaster reflex is lost.", "cop": 1, "opa": "Genital branch of genitofemoral nerve", "opb": "Ilioinguinal nerve", "opc": "Iliohypogastric nerve", "opd": "Femoral nerve", "subject_name": "Anatomy", "topic_name": "Male Genital System", "id": "1d4f5659-bb1f-40fd-a619-56ed6cbbe0c6", "choice_type": "single"} {"question": "An example of tumor suppressor gene is", "exp": "Ref Robbins 7/e p300; , Harrison 17/e p499; 9/e p290 Tumor suppressor genes are the genes whose products down regulate the cell cycle. RB Gene: Governor of the Cell Cycle It is useful to begin with the retinoblastoma gene (RB), the first tumor suppressor gene to be discovered and, as it happens, a prototypical representative. As with many advances in medicine, the discovery of tumor suppressor genes was accomplished by the study of a rare disease--in this case, retinoblastoma, an uncommon childhood tumor. Approximately 60% of retinoblastomas are sporadic, and the remaining ones are familial, the predisposition to develop the tumor being transmitted as an autosomal dom- inant trait. To account for the sporadic and familial occur- rence of an identical tumor, Knudson, in 1974, proposed his now famous two-hit hypothesis, which in molecular terms can be stated as follows: * Two mutations (hits) are required to produce retinoblas- toma. These involve the RB gene, which has been mapped to chromosomal locus 13q14. Both of the normal alleles of the RB locus must be inactivated (hence the two hits) for the development of retinoblastoma (Fig. 5-21). * In familial cases, children inherit one defective copy of the RB gene in the germ line; the other copy is normal. brakes to cellular proliferation Rb gene is a tumor suppressor gene whereas My ,fos and Ra's are all example of proto oncogene Retinoblastoma develops when the normal RB gene is lost in retinoblasts as a result of somatic mutation. Because in retinoblastoma families only a single somatic mutation is required for expression of the disease, the familial transmission follows an autosomal dominant inheritance pattern. * In sporadic cases, both normal RB alleles are lost by somatic mutation in one of the retinoblasts. The end result is the same: a retinal cell that has lost both of the normal copies of the RB gene becomes cancerous. Although the loss of normal RB genes initially was discovered in retinoblastomas, it is now evident that homo- zygous loss of this gene is a fairly common feature of several tumors, including breast cancer, small cell cancer of the lung, and bladder cancer. Patients with familial retinoblastoma also are at greatly increased risk for development of osteosarcomas and some soft tissue sarcoma The RB gene product is a DNA-binding protein that is expressed in every cell type examined, where it exists in an active hypophosphorylated state and an inactive hyperphosphor- ylated state. The impoance of Rb lies in its regulation of the G1/S checkpoint, the poal through which cells must pass before DNA replication commences. As background for an understanding of how tumor sup- pressors function, it is useful to briefly revisit the cell cycle: In embryos, cell divisions proceed at an amazing clip, with DNA replication beginning immediately after mitosis ends. As development proceeds, however, two gaps are incorpo- rated into the cell cycle: gap 1 (G1) between mitosis (M) and DNA replication (S), and gap 2 (G2) between DNA replica- tion (S) and mitosis (M) (Fig. 5-20). Although each phase of the cell cycle circuitry is monitored carefully, the transi- tion from G1 to S is believed to be an extremely impoant checkpoint in the cell cycle \"clock.\" Once cells cross the G1 checkpoint they can pause the cell cycle for a time, but they are obligated to complete mitosis. In G1, however, cells can remove themselves entirely from the cell cycle, either tem- porarily (quiescence, or G0) or permanently (senescence). Indeed, during development, as cells become terminally differentiated, they exit the cell cycle and enter G0. Cells in G0 remain there until external cues, such as mitogenic sig- naling, push them back into the cell cycle. In G1, therefore, diverse signals are integrated to determine whether the cell should progress through the cell cycle, or exit the cell cycle and differentiate, and Rb is a key hub integrating external mitogenic and differentiation signals to make this decision. To appreciate this crucial role of Rb in the cell cycle, it is helpful to review the mechanisms that enforce the G1/S transition. * The initiation of DNA replication (S phase) requires the activity of cyclin E/CDK2 complexes, and expression of cyclin E is dependent on the E2F family of transcription factors. Early in G1, Rb is in its hypophosphorylated active form, and it binds to and inhibits the E2F family of transcription factors, preventing transcription of cyclin E. Hypophosphorylated Rb blocks E2F-mediated transcription in at least two ways (Fig. 5-22). First, it sequesters E2F, preventing it from interacting with other transcriptional activators. Second, Rb recruits chromatin remodeling proteins, such as histone deacetylases and histone methyltransferases, which bind to the promoters of E2F-responsive genes such as cyclin E. These enzymes modify chromatin at the promoters to make DNA insen- sitive to transcription factors. This situation is changed on mitogenic signaling. Growth factor signaling leads to cyclin D expression and activa- tion of cyclin D-CDK4/6 complexes. These complexes phosphorylate Rb, inactivating the protein and releasing E2F to induce target genes such as cyclin E. Expression of cyclin E then stimulates DNA replication and pro- gression through the cell cycle. When the cells enter S phase, they are committed to divide without additional growth factor stimulation. During the ensuing M phase, the phosphate groups are removed from Rb by cellular phosphatases, regenerating the hypophosphorylated form of Rb. * E2F is not the sole target of Rb. The versatile Rb protein binds to a variety of other transcription factors that regulate cell differentiation. For example, Rb stimulates myocyte-, adipocyte-, melanocyte-, and macrophage- specific transcription factors. Thus, the Rb pathway couples control of cell cycle progression at G0-G1 with differentiation, which may explain how differentiation is associated with exit from the cell cycle. In view of the centrality of Rb to the control of the cell cycle, an interesting question is why RB is not mutated in every cancer. In fact, mutations in other genes that control Rb phosphorylation can mimic the effect of RB loss; such genes are mutated in many cancers that seem to have normal RB genes. For example, mutational activation of CDK4 or overexpression of cyclin D ors cell proliferation by facil- itating Rb phosphorylation and inactivation. Indeed, cyclin D is overexpressed in many tumors because of gene ampli- fication or translocation. Mutational inactivation of CDKIs also would drive the cell cycle by unregulated activation of cyclins and CDKs. As mentioned earlier, the CDKN2A gene is an extremely common target of deletion or muta- tional inactivation in human tumors. The emerging paradigm is that loss of normal cell cycle control is central to malignant transformation and that at least one of the four key regulators of the cell cycle (CDKN2A, cyclin D, CDK4, Rb) is mutated in most human cancers. Fuhermore, the transforming proteins of several oncogenic human DNA viruses act, in pa, by neutralizing the growth inhibi- tory activities of Rb. For example, the human papillomavi- rus (HPV) E7 protein binds to the hypophosphorylated form of Rb, preventing it from inhibiting the E2F transcrip- tion factors. Thus, Rb is functionally deleted, leading to uncontrolled growth", "cop": 4, "opa": "Myc", "opb": "Fos", "opc": "Ras", "opd": "Rb", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "926fdc5f-cd8e-44b0-a5b2-9fddd134cb27", "choice_type": "single"} {"question": "Neutrophils secrete", "exp": "Ref Robbins 9/e p 73 Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17. MPO is most abundantly expressed in neutrophil granulocytes (a subtype of white blood cells), and produces hypohalous acids to carry out their antimicrobial activity. It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation. Neutrophil myeloperoxidase has a heme pigment, which causes its green color in secretions rich in neutrophils, such as pus and some forms of mucus. The green color contributed to its outdated name verdoperoxidase", "cop": 2, "opa": "Superoxide dismutase", "opb": "Myeloperoxidase", "opc": "Lysosomal enzyme", "opd": "Catalase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f4d21570-0d74-4897-b423-7bec8d6c2987", "choice_type": "single"} {"question": "Ala of sacrum is not crossed by", "exp": "Ans. is 'd' i.e., UreterThe smooth medial pa of the ala of sacrum is associated with the subsequent 4 structures from medial to lateral side: 1. Sympathetic chain. 2. Lumbosacral trunk. 3. Iliolumbar aery. 4. Obturator nerve.The ventral ramus of L5 nerve is really tight that it grooves the ala.The rough lateral pa of the ala provides origin to iliacus muscle anteriorly and connection to the lumbosacral ligament posteriorly.", "cop": 4, "opa": "Sympathetic chain", "opb": "Iliolumbar aery", "opc": "Obturator nerve", "opd": "Ureter", "subject_name": "Anatomy", "topic_name": null, "id": "4751133e-cebc-4b82-9d3c-b9bb4f5814bb", "choice_type": "single"} {"question": "One bullet get lodged in the barrel in the previous firing and dislodged with the second bullet in the subsequent firing in", "exp": "Tandem bullet( Piggy tail bullet) One bullet gets lodged in the barrel in the previous firing and dislodged with the second bullet in the subsequent firing. These bullets may separate before entering the body and produce two entrance wounds on a single firing. Sometimes, they may separate after entering the body and make two exit wounds. Sometimes, two bullets may remain inside the body making no exit wound. In some cases, one bullet will go producing one exit wound and the other will remain inside. In a single catridge, one bullet is set behind the other by notching on the base and in one shot two bullets are discharged. It is called duplex or tandem catridge. These types of catridges are used in some military rifles. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 141", "cop": 2, "opa": "Frangible bullet", "opb": "Piggy tail bullet", "opc": "Incendiary bullet", "opd": "Dum dum bullet", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "7e16f63c-83cf-4544-82a7-dde0b21a657b", "choice_type": "single"} {"question": "anorexia management is assosiated with", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "obesity", "opb": "avoid using rest room for 2 hours after food intahke", "opc": "overweight", "opd": "metabolic syndrome", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "d3caa6c8-3c19-4b9d-aeb0-556f79302f9d", "choice_type": "single"} {"question": "Lambda is the junction between", "exp": "The lambdoid suture lies between the occipital bone and the two parietal bones.sutural or Wormian bones are common along this suture. Lambda, parietal foramina, and obelion have been examined in the norma veicalis. Ref BDC volume:3,6th edition", "cop": 3, "opa": "Occipital and frontal bones", "opb": "Frontal and temporal bones", "opc": "Parietal and occipital bones", "opd": "Frontal and parietal bones", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "98bcd132-8262-4b06-968c-8284bcdb3098", "choice_type": "single"} {"question": "Ligament of poupart is", "exp": "Ligament of poupart is another name for Inguinal ligament", "cop": 4, "opa": "Linea alba", "opb": "Pectineal ligament", "opc": "Lacunar ligament", "opd": "Inguinal ligament", "subject_name": "Anatomy", "topic_name": null, "id": "e5d4a9c1-c129-4b4a-a018-1d9ae1610247", "choice_type": "single"} {"question": "External anal sphincter is innervated by", "exp": "External anal sphincter is controlled by spinal nerves from the S2, S3 and S4 levels of your spinal cord, which form the pudendal nerve. ref - BDC vol2 pg 412-416", "cop": 4, "opa": "L4, L5", "opb": "L5, S1", "opc": "S1, S2, S3", "opd": "S2, S3, S4", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "11b0f6d1-5938-406a-80cd-e598ed892f5e", "choice_type": "single"} {"question": "The normal narrowing in the middle of the oesophagus is caused by", "exp": "Middle constriction of oesophagus is due to left bronchus .27.5cm/11 inch from insisor teeth. BD CHAURASIA&;S HUMAN ANATOMY VOLUME 1, 6TH Edition . page no 282, fig 20.7", "cop": 4, "opa": "Azygos vein", "opb": "Hemiazygos vein", "opc": "Right main stem bronchus", "opd": "Left main stem bronchus", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "e6f22617-9b42-4842-86b5-4a925665c834", "choice_type": "single"} {"question": "Cell surface molecules involved in peripheral tolerance", "exp": "Ref Robbins 7/e p225 , Harrison 16/e p1907, Robbins 9/e p213 B7 is a type of peripheral membrane protein found on activated antigen presenting cells that, when paired with either a CD28 or CD152 surface protein on a T cell, can produce a costimulatory signal", "cop": 1, "opa": "B7 and CD28", "opb": "CD40 and CD40L", "opc": "CD 34 and CD51", "opd": "B7 and CD3", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "faa319da-6236-442e-ba6a-b818b4dc9eda", "choice_type": "single"} {"question": "First sign of wound injury is", "exp": "ref Robbins 8/e p46 ,102 ; 7/e p107,9/e p106 Some redness is normal at the wound site, but it should diminish over time. However, if your surgical incision or wound continues to be red or exhibit radiating streaks known as lymphangitis, this is a warning sign of awound infection .red Ness due to vasodilation", "cop": 2, "opa": "Epithelization", "opb": "Dilatation of capillary", "opc": "Leukocyte infiltration", "opd": "Locatised odema", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f3972338-27ce-41ed-80f8-3fd37e223ce1", "choice_type": "single"} {"question": "The following parasite infection predispose to malignancies", "exp": "Ref Robbins 8/e p880; 9/e p874 The following two parasites have definitive ethilogical association with malignancies: Clonorchis sinensis : cholangiocarcinoma Opisthorchis viveerini: cholangiocarcinoma Schistosoma japonicum: colorectal cancer", "cop": 3, "opa": "Paragonimus westermani", "opb": "Guinea work infection", "opc": "Clonorchiasis", "opd": "Schistosomiasis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f1b17ef8-15b6-418d-a4d7-5bb954dbe931", "choice_type": "single"} {"question": "Yellowish discoloration of the mucus membrane and teeth is produced by", "exp": "Nitric acid- signs and symptoms They are similar to that of sulphuric acid. The abdominal pain and belching may be more. There may be severe cough, dysnoea, and breathlessness due to inhalation of fumes and irritation of air passages. There will be corrosion and yellow discoloration of the mucus membrane and teeth. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 409", "cop": 2, "opa": "Sulphuric acid", "opb": "Nitric acid", "opc": "Carbolic acid", "opd": "Hydrochloric acid", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "fbae845c-d346-4bf3-a7ec-bd32e0ef41ff", "choice_type": "single"} {"question": "In case of direct occipito posterior position most commonly encountered problem is", "exp": "In face to pubis delivery the most common complication is perineal tear as the occiput is posterior and thus the longer biparietal diameter distends the perineum rather than the smaller bitemporal diameter.Hence in all such cases liberal episotomy should be given", "cop": 4, "opa": "Intracranial injury", "opb": "Cephalhematoma", "opc": "Paraurethral tears", "opd": "Complete perineal tears", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "745f5dfa-fe5e-4850-bc31-22c45258600f", "choice_type": "single"} {"question": "Brainstem nucleus not derived from the alar plate", "exp": "Hypoglossal nucleus is a pure motor nucleus derived from the anterior basal plate neural tube Posterior alar plate gives sensory (not motor) nuclei. Ref: Gray's39e/p-518", "cop": 3, "opa": "Dentate", "opb": "Inferior olivary", "opc": "Hypoglossal", "opd": "Substantia nigra", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "8da8f53f-e3e4-4c32-9931-310d0520500c", "choice_type": "single"} {"question": "In giant cell tumor of the bone.,the cell of origin is", "exp": "The Neoplastic cells of giant cell tumor are primitive osteoblast precursors but they represent only a minority of the tumor cells.The bulk of the tumor consists of non Neoplastic osteoclast and their precursors Ref Robbins page no 1203", "cop": 3, "opa": "Fibroblst cells", "opb": "Osteoclast and precursors", "opc": "Osteoblast and precursors", "opd": "Sinusoidal cells", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "8968c9e7-e332-4baa-9396-4de241efdf1a", "choice_type": "single"} {"question": "Schiller Duval bodies are seen in", "exp": "Refer Robbins page no 1031", "cop": 3, "opa": "Teratoma", "opb": "Seminoma", "opc": "Yolk sad tumor", "opd": "Choriocarcionma", "subject_name": "Anatomy", "topic_name": "Breast", "id": "8fb9e524-832f-4393-b9bc-eaae46be6050", "choice_type": "single"} {"question": "Assesment of progress of labor is best done by", "exp": "Paogram is the best method to assess progress of labor", "cop": 4, "opa": "Station of head", "opb": "Rupture of membranes", "opc": "Contraction of uterus", "opd": "Paogram", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "5902e603-e40f-4ec1-b76b-7b055a7e0f05", "choice_type": "single"} {"question": "A 26 years male person has got injury to mid arm patient developed wrist drop, finger drop, loss of sensation and dorsum of hand, patient is able to do elbow extension, the diagnosis is", "exp": "Very high radial nerve palsy ----elbow extension lost, wrist drop, finger drop High radial nerve palsy ----wrist drop, finger drop Low radial nerve palsy ----finger drop, no wrist drop Refer maheswari 9th ed", "cop": 2, "opa": "Very high radial nerve injury", "opb": "High radial nerve injury", "opc": "Low radial nerve injury", "opd": "Posterior Interooseus nerve", "subject_name": "Anatomy", "topic_name": null, "id": "e9435a43-ac7b-4eb3-b481-289e2793090e", "choice_type": "single"} {"question": "A 21 year old patient attended a pay the previous night and gives the following symptoms, pain in abdomen radiating to back, pulse 100/min, BP 100/76, Temp 39degC and vomiting before coming. Most probable diagnosis is", "exp": "Clinical features of acute pancreatitis Cardinal symptoms : Epigastric and /or peri umbilical pain that radiates to the back, relieved by sitting & leaning forward Upto 90% of patients have nausea and/or vomiting that typically does not releive on pain Nature of the pain is constant Dehydration, poor skin turgor, tachycardia, hypotension & dry mucous membranes are commonly seen in patients with AP Mild-pancreatitis: Abdomen may be normal of reveal only mild epigastric tenderness Severe pancreatitis : Significant abdominal distension, associated with generalised rebound tenderness and abdominal rigidity Flank (Grey Turner), peri umbilical (cullen's sign) & inguinal ecchymosis (Fox sign) are indicative of retro peritoneal bleeding associated with severe pancreatitis Dullness to percussion and decreased breathing sounds in left or less commonly, in the right hemithorax suggest pleural effusion Ref : Sabiston 20th edition Pgno :1524-1528", "cop": 4, "opa": "Acute appendicitis", "opb": "Acute cholecystitis", "opc": "Acute diveiculitis", "opd": "Acute pancreatitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "97823612-86f9-4a26-a656-b624e244e55e", "choice_type": "single"} {"question": "Skin pigmentation resembling 'rail road tracks' seen in", "exp": "Chronic opium poisoning They have dry skin with needle puncture marks and sometimes masked by tattooing. Abscesses and thrombosed veins may be seen. I. V users may develop pigmentation and scars on front of the elbow called railroad tracks. Drug addicts may tattoo this area to mask the scars. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 489", "cop": 2, "opa": "Marijuana", "opb": "Opium", "opc": "Barbiturates", "opd": "Alcohol", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "2aa28c73-2324-4d41-80b1-f419ebf12e48", "choice_type": "single"} {"question": "Abduction of Hand is caused by", "exp": "The flexor carpi radialis muscle originates from the medial epicondlyle of humerus and inses into the bases of 2nd and 3rd metacarpal bones. Its action is abduction of hand at the wrist joint. BD CHAURASIA 7th edition ,page 108 table 9.2", "cop": 1, "opa": "FCR", "opb": "FCU", "opc": "FDP", "opd": "FDS", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "ab172f73-30d1-4996-a212-d16694612a76", "choice_type": "single"} {"question": "Mitochondrial chromosomal abnormality leads to", "exp": "Ref Robbins 8/e p171;9/e p172 Example of mitochondrial inheritance is leber's hereditary optic neuropathy.leigh's disease ,MELAS - Mitochondrial encephalopathy Lactic acid Stroke like syndrome Neuropathy , ataxia, retinitis, Kearns Sayre syndromes, chronic progressive external opthalmoplegia,Pearson syndrome M", "cop": 1, "opa": "Leber's hereditary optic neuropathy", "opb": "Angelman syndrome", "opc": "Prader villi syndrome", "opd": "Myotonic dystrophy", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b48da862-312f-4ae1-ba72-346d5c4c2e96", "choice_type": "single"} {"question": "Rosette shaped arrangement of cells is seen in", "exp": "An ependymoma is a glial tumor of the ependymal cells that line the center of the spinal cord and the ventricles of the brain. There are several different types of ependymoma cancers, which are also classified by grade. The three grades used for ependymoma cancers are determined by how closely the cancer cells resemble normal cells. The lower the grade, the more closely the cancer cells resemble normal cells. The different types of ependymomas appear in different locations within the spinal column or brain. Grade I tumors - These include subependymomas and myxopapillary ependymomas, and are typically slow growing. Myxopapillary ependymomas tend to appear at the lower end of the spinal column. Subependymomas appear near a ventricle in the brain. These ventricles are involved in the creation of cerebrospinal fluid. Grade II tumors - These are the most common ependymomas. Many ependymoma subtypes exist in this grade, including cellular, papillary, tancytic, RELA fusion-positive, and clear cell ependymomas. These may appear anywhere along the ventricular system where cerebrospinal fluid is produced. Grade III tumors - These are known as anaplastic ependymomas and are typically faster growing than the other grades. Anaplastic ependymomas are usually found in the skull, brain, and brain stem. They are rarely found in the spinal cord. Refer robbins 9/e 1334", "cop": 2, "opa": "Thecoma of ovary", "opb": "Ependymoma", "opc": "Neurofibroma", "opd": "Lymphoma", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "ecbb7821-81c4-489d-adf8-37ac28e7f342", "choice_type": "single"} {"question": "Nerve supply to the perineum is", "exp": "Pudendal nerve, its course through the lesser sciatic foramen, and branches, including inferior anal at bottom right. The superficial branches of the internal pudendal aery. The perineal nerve is a nerve arising from the pudendal nerve that supplies the perineum. Ref - BDC 6e vol2 pg363", "cop": 1, "opa": "Pudendal nerve", "opb": "Inferior rectal nerve", "opc": "Pelvic splanchnic nerves", "opd": "Hypogastric plexus", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ff61f891-ccd7-4a97-8de8-573e3031c7e5", "choice_type": "single"} {"question": "Peripheral hea is another name for", "exp": "There are large valveless venous sinuses in the substance of soleus. When it contracts, the blood is pumped out of them and during rest the blood stagnates in them. Soleus is also known as because it actively helps in the venous return from the lower limb. (Ref: Gray's Anatomy, Churchill Livingstone, New York; 2005; 879 - 880.)", "cop": 2, "opa": "Gastrocnemius muscle", "opb": "Soleus muscle", "opc": "Plantaris muscle", "opd": "Popliteus muscle", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "792a1af3-30a1-44d8-8a8d-89ce0cb4d08e", "choice_type": "single"} {"question": "In Hashimotos thyroiditis there is infiltration of", "exp": "Robbins page no 1087MORPHOLOGY The thyroid is often diffusely enlarged, although more localized enlargement may be seen in some cases. The capsule is intact, and the gland is well demarcated from adjacent structures. The cut surface is pale, yellow-tan, firm, and somewhat nodular. There is extensive infiltration of the parenchyma by a mono- nuclear inflammatory infiltrate containing small lympho- cytes, plasma cells, and well-developed germinal centers (Fig. 24-11). The thyroid follicles are atrophic and are lined in many areas by epithelial cells distinguished by the presence of abun- dant eosinophilic, granular cytoplasm, termed Huhle cells. This is a metaplastic response of the normally low cuboidal follicular epithelium to ongoing injury. In fine-needle aspiration biopsy samples, the presence of Huhle cells in conjunction with a heterogeneous population of lymphocytes is character- istic of Hashimoto thyroiditis. In \"classic\" Hashimoto thyroiditis, interstitial connective tissue is increased and may be abundant. Unlike Reidel thyroiditis (see later), the fibrosis does not extend beyond the capsule of the glands", "cop": 3, "opa": "Macrophages", "opb": "Neutrophiks", "opc": "Leukocytes", "opd": "Eosinophils", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "0e525fe1-0b66-426a-9c3a-1dc70cc97603", "choice_type": "single"} {"question": "systematic sensitization is used in", "exp": "SYSTEMATIC DESENSITIZATION JOSEPH WOLPE Joseph Wolpe gave the concept of systematic desensitization This is a treatment used in phobia In phobia there is a conditioned fear response to aversive neutral stimulus and avoidance of that response leads to phobia Whenever there is a fear response there is stimulation of sympathetic system In that case stimulation of parasympathetic system by relaxation there is reduction in anxiety First step is to make a step ladder which are arranged based on the severity Then is go step by step and along with doing applied relaxation Slowly the the sympathetic system is reduced The patient will be able to approach stimulus without anxiety Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 2, "opa": "dissosiation", "opb": "phobia", "opc": "schioid personality", "opd": "psychosis", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "5b11c7e8-7b55-45e2-89e8-0b11352de959", "choice_type": "single"} {"question": "Premature fusion of coronal, sphenofrontal and ethmoidal sutures seen in", "exp": "Turricephaly : Cone shaped head caused by premature fusion of coronal sphenofrontal and frontoethmoidal sutures. Dolichocephaly: Due to premature closure of sagittal suture , produces a long and narrow skull, Also called scaphocephaly Plagiocephaly: Asymmetrical distoion or flattening of one side of the skull. Trigoncephaly: Caused by premature fusion of metopic suture; Keel shaped forehead, and hypotelorism, increased risk for associated developmental abnormalities of the forebrain. Ref: Nelson's 20th edition, page- 71-72.", "cop": 1, "opa": "Turricephaly", "opb": "Dolichocephaly", "opc": "Plagiocephaly", "opd": "Trigoncephaly", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e40375e4-b3d1-445e-b876-8abcec2943ed", "choice_type": "single"} {"question": "Concha and Eminent Concha are supplied by", "exp": "The auricular branch arises from the superior ganglion of the vagus. It crosses the facial canal 4 mm above the stylomastoid foramen, emerges through the tympanomastoid fissure, and ends by supplying the concha and root of the auricle, the posterior half of the external auditory meatus, and the tympanic membrane (outer surface)Reference: Chaurasia Head and Neck; 6th edition; Vagus nerve", "cop": 4, "opa": "Great Auricular Nerve", "opb": "Lesser Occipital Nerve", "opc": "Auriculotemporal Nerve", "opd": "Auricular Branch of Vagus nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ed4df00f-ccf5-4b11-9ef2-9b9213ea97f5", "choice_type": "single"} {"question": "U shaped dose response curve is seen in", "exp": "U shaped response curve is seen in vitamins Ref-Goodman and Gillman 12/e p74", "cop": 1, "opa": "Vitamins", "opb": "Anti cancer drugs", "opc": "Steroids", "opd": "Chelators", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "629224a1-c27d-4bff-87be-c362565e74d6", "choice_type": "single"} {"question": "Pseudorosettes are seen in", "exp": "Microscopic pathological study in Retinoblastoma shows various patterns like Homer-wright Flexner wintersteiner Fleurettes Refer khurana 6/e", "cop": 1, "opa": "Retinoblastoma", "opb": "Ophthalmia nodosa", "opc": "Phacolytic glaucoma", "opd": "Trachoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1ab5ff17-c5a4-4853-b0c9-2e89ceae29bb", "choice_type": "single"} {"question": "The free edge of the falciform ligament encloses", "exp": "The liver is divided into right and the left lobes by the attachment of the falciform ligament anteriorly and superiorly; by the fissure for the ligamentum teres inferiorly; and by the fissure for the ligamemtum venosum posteriorly. Ligamentum teres is a degenerative string of tissue that exists in the free end of the falciform ligament. Ref -researchgate.net", "cop": 3, "opa": "Ligamentum venosum", "opb": "Poal vein and common bile duct", "opc": "Ligamentum teres", "opd": "Superior epigastric vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "84bf9db7-b443-492c-99a3-6514c2a246a1", "choice_type": "single"} {"question": "Fear of height is", "exp": "Acrophobia- fear of height Agoraphobia- fear of open place Claustrophobia- fear of closed spaces Hapnophobia - fear of touch Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 361", "cop": 1, "opa": "Acrophobia", "opb": "Agoraphobia", "opc": "Claustrophobia", "opd": "Hapnophobia", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "12bb8859-64a2-444f-9b63-dc852180806c", "choice_type": "single"} {"question": "Infection draining the index finger goes to", "exp": "Infection in the index finger drains into thenar space Infection from 3, 4, 5th fingers drains into mid-palmar space Spaces: Flexor pollicis longus tendon have radial bursa towards radius bone. Ulnar bursa is on the synol sheath of flexor tendons which continues with the little finger (flexor digitorum Tendon) If there is infection in pulp space of thumb there would be radial bursitis. Lumbrical 1 relates with thenar space But lumbricals 2, 3, 4 canals would be continuous with mid-palmar space forearm space of Parona (which is filled with pus sometimes due to ulnar / radial bursitis) Midpalmar and Thenar Spaces FDS:Flexor digitorum superficialis FDP: Flexor digitorum profundus FPL: Flexor pollicis longus", "cop": 1, "opa": "Thenar space", "opb": "Midpalmar space", "opc": "Ulnar bursa", "opd": "Radial bursa", "subject_name": "Anatomy", "topic_name": "Upper limb : Miscellaneous", "id": "ac7f1212-83e1-4fb0-9447-904cfae815ff", "choice_type": "single"} {"question": "Increase in the height of child from 1 to 3 yrs", "exp": "Height at 1yr is 75cm and at 4 yrs is 100cms. So increase in height from 1-4 yrs is 25cms Height at 2yrs is 90 cms.So increase in height from 1-2 yrs is 15cms Hence, increase in height from 1-3 yrs should fall between 15 to 25cms. Ref: Ghai,9th edition, Table 2.3", "cop": 3, "opa": "10cms", "opb": "15cms", "opc": "20cms", "opd": "25cms", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e03bb573-f000-44d7-90be-c0048f61cbe5", "choice_type": "single"} {"question": "Contraindication of Enteral Nutrition A) Intestinal obstruction B) Severe pancreatitis C) Severe diarrhoea D) IBD E) Intestinal fistula", "exp": "Enteral Nutrition Indications Protein - Energy malnutrition with inadequate oral intake Dysphagia except for fluids Major trauma (or surgery) when return to required dietary intake is Prolonged Inflammatory bowel disease Distal, low output (<200 ml/day) enterocutaneous fistula To enhance adaptation after massive enterectomy Contraindications Small bowel obstruction or ileus Severe diarrhoea Proximal small intestinal fistula Severe pancreatitis Ref: Sabiston 20th edition Pgno :112", "cop": 3, "opa": "A, B, C", "opb": "A, B, C, D", "opc": "A, B, C, E", "opd": "A, C, E", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "2bf92de5-8f1a-4640-99c1-b6573138394a", "choice_type": "single"} {"question": "Thinnest pa of the skull", "exp": "The anterior pa of the floor of the temporal fossa is crossed by an H shaped suture where four bones,frontal,parietal,greater wing of sphenoid and temporal adjoin each other.This area is termed the pterion. REF.B D Chaurasia's Human Anatomy VOL.3,Fouh edition", "cop": 3, "opa": "Lambdoid suture", "opb": "Temporal pa of bone", "opc": "Pterion", "opd": "Occiput", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "13e88c5e-563a-4109-9e3c-020b1643a54b", "choice_type": "single"} {"question": "Scar in lung tissue may get transformef into", "exp": "Impoant points about squamous cell carcinoma of lung MC type of lung cancer in smokers MC type in males Usually central in location Intracellular bridges or junction is very specific Hyercalcemia due to PTHrP is the NC paraneoplastic syndrome. Refer robbindp716-717f", "cop": 3, "opa": "Adenocarcinoma", "opb": "Oat cell carcinoma", "opc": "Squamous cell carcinoma", "opd": "Columnar cell carcinoma", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "2fb41546-68b5-4120-9a60-bff95de3a5cb", "choice_type": "single"} {"question": "Poal vein supplies", "exp": "The poal vein or hepatic poal vein is a blood vessel that carries blood from the gastrointestinal tract and spleen to the liver. This blood is rich in nutrients that have been extracted from food, and the liver processes these nutrients; it also filters toxins that may have been ingested with the food. Ref - BDC 6e vol2 pg282", "cop": 2, "opa": "Spleen", "opb": "Liver", "opc": "Pancreas", "opd": "Colon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "da9a1d70-ca39-4514-96d2-23df89cb1097", "choice_type": "single"} {"question": "The given histological specimen is", "exp": null, "cop": 2, "opa": "Urethra", "opb": "Vermiform appendix", "opc": "Vas deferens", "opd": "Stenson's duct", "subject_name": "Anatomy", "topic_name": null, "id": "b1dbef3a-9282-48bf-91ae-211ee6415af2", "choice_type": "single"} {"question": "The pectoralis major is classifies as a", "exp": "Pectoralis major muscle is typically classified as a spiral Muscle. Muscles with spiral or twisted fasciculi are found in Trapezius, Pectoralis major, Latissimus dorsi, and supinator. Spiral or Twisted: The muscle fibers undergo a twist of approximately 180 degrees between their medial and lateral attachement. Spiral or Twisted Muscle: Pectoralis major Latissimus dorsi Trapezius Supinator Some skeletal muscles may be classified into more than one category. Pectoralis Major muscle has been classified both as convergent (or Triangular muscle) and Spiral Muscle in different textbooks. Note that Pectoralis major has been classified as &;Spiral &; in Gray&;s text and hence this has been selected as the single best answer of choice for this question. Convergent may be selected as the correct answer if spiral is not provided amongst the options. Ref: Gray&;s anatomy 41st edition Pgno: 113", "cop": 1, "opa": "Spiral Muscle", "opb": "Cruciate muscle", "opc": "Fusiform muscle", "opd": "Bipennate Muscle", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "551419bc-ddb4-43f7-8d39-f4ba6c6daefe", "choice_type": "single"} {"question": "Colon contains", "exp": "Mucous glands: Cell of mucous acini are tall with flat nuclei at their bases. The lumen of these acini is larger than the serous acini. In mucous glands the secretion contains mucopolysaccharides. The secretion collects in the apical pas of the cells. As a result nuclei are pushed to the base of the cell, and may be flattened. In classroom slides stained with haematoxylin and eosin, the secretion within mucous cells remains unstained so that they have an 'empty' look. However, the stored secretion can be brightly stained using a special procedure called the periodic acid Schiff (PAS) method. Unicellular cells secreting mucus are numerous in the intestines, they are called goblet cells because of their peculiar shape. REF : Inderbir Singh's Textbook of Human Histology, Seventh edition,pg.no.,56.", "cop": 4, "opa": "Parietal cells", "opb": "Chief cells", "opc": "Brunner's gland", "opd": "Goblet cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "21281e47-f9b1-43f0-b75f-66418536a6e8", "choice_type": "single"} {"question": "'Nodding face sign' is seen in", "exp": "Hinge/Transverse fracture: Transverse fracture of the base of the skull occurs on middle that completely splits it into two halves, creating hinge (nodding face sign) .This may result from an impact on either side of head or side to side compression of head as in run over by vehicle. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 165", "cop": 3, "opa": "Fracture of anterior cranial fossa", "opb": "Fracture of middle cranial fossa", "opc": "Hinge fracture", "opd": "Orbital blow out fractures", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "59408f3a-9944-4352-8e35-ac927b383464", "choice_type": "single"} {"question": "The optic foramen is located between", "exp": "The optic foramen/canal is the opening of the optic canal. It is bounded medially by the body of the sphenoid and laterally by the lesser wing of sphenoid. Contents: Optic nerve and ophthalmic aery Ref: BD Chaurasia; 6th edition", "cop": 3, "opa": "Greater wing and lesser wing of sphenoid", "opb": "Greater wing and body of sphenoid", "opc": "Lesser wing and body of sphenoid", "opd": "Lesser wing of sphenoid and ethmoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "12ed67dc-f57c-4093-ab30-ed8ca28093b8", "choice_type": "single"} {"question": "Nerve supply of trapezius is by", "exp": "the and sternocleidomastoid are supplied by spinal accessory nerve. Both of them develop from brachial arch mesoderm. The principal action of trapezius is to rotate scapula during abduction of arm beyond 90deg. Clinically the muscle is tested by asking the patient to shrug his shoulder against resistance. REF: BD Chaurasia 7th edition Page no: 64.", "cop": 4, "opa": "Axillary", "opb": "Musculocutaneous", "opc": "Median", "opd": "Spinal accessory nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "1537d19c-47b3-4a9a-a28e-a5b70a2f29f9", "choice_type": "single"} {"question": "G couple protein receptor is", "exp": "Ref-katzung 11/e p359 Metabotropic receptor are G-protein receptors", "cop": 1, "opa": "Metabotropic receptor", "opb": "Ionic receptor", "opc": "Kinase-linked receptor", "opd": "Nuclear receptor", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "277ca077-0a94-48ab-b97b-4ab325c6d9cf", "choice_type": "single"} {"question": "Indications for needle aspiration in liver abscess are", "exp": "Therapeutic needle aspiration of amebic abscesses has been proposed. However, a Cochrane systematic review did not suppo any benefit of therapeutic aspiration in addition to metronidazole treatment over metronidazole treatment alone to hasten clinical or radiologic resolution of amebic liver abscesses.19 In general, aspiration is recommended for diagnostic unceainty, with failure to respond to metronidazole therapy in 3 to 5 days, or in abscesses thought to be at high risk for rupture. Abscesses Larger than 5 cm in diameter and in the left liver are thought to carry a higher risk of rupture, and aspiration should be considered. Ref: Sabiston 20th edition Pgno :1452", "cop": 2, "opa": "Recurrent", "opb": "Left lobe", "opc": "Refractory to treatment after 48- 72 hours", "opd": "Multiple", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "14342466-44e3-4f06-87f8-31b2b4d879eb", "choice_type": "single"} {"question": "Acute osteomyelitis is caused by", "exp": "It is caused most commonly by staphylococcus aureus Refer Maheshwari 6th/e p 168", "cop": 1, "opa": "Staphylococcus aureus", "opb": "Actinomyces bovis", "opc": "Nocardia asteroids", "opd": "Borelia vincenti", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "28c5b41d-647a-4d80-b7a7-57101527b9e1", "choice_type": "single"} {"question": "Loss of corneal reflex is due to injury of", "exp": "Loss of corneal reflex may result due to injury of Ophthalmic division of trigeminal nerve (afferent limb) or injury of Facial nerve (efferent limb).", "cop": 1, "opa": "Ophthalmic division of trigeminal nerve", "opb": "Optic nerve", "opc": "Oculomotor nerve", "opd": "1 and 2.", "subject_name": "Anatomy", "topic_name": "Cranial Nerves", "id": "b7a0146c-067c-4325-b9a7-974eddf93d9d", "choice_type": "single"} {"question": "Palpation on the costoveebral angle produces pain and tenderness in acute adrenal insufficiency.This is", "exp": "Costoveebral angle pain and tenderness in acute adrenal insufficiency is known as Rogoff's sign.", "cop": 3, "opa": "Rotch's sign", "opb": "Rossolimo\"s sign", "opc": "Rogoff's sign", "opd": "Osler's sign", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "153bdf31-a65c-41ee-bcc9-060cc6039971", "choice_type": "single"} {"question": "A woman presents with chest pain and shoulder pain. On examination, she is found to have pericarditis with pericardial effusion. This shoulder pain is mediated by", "exp": "The pain of pericarditis is mediated by the phrenic nerve. The somatic sensation from the pericardium is carried by the somatic afferent fibers of the phrenic nerve. The pericardial pain may be referred to the supraclavicular region of the shoulder or lateral neck area (dermatomes C3, C4 and C5. Ref: Gray&;s Anatomy for students 3rd edition Pgno: 183", "cop": 3, "opa": "Deep cardiac plexus", "opb": "Superficial cardiac plexus", "opc": "Phrenic nerve", "opd": "Subcostal nerve", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "3d3a4188-074a-4822-8f01-e7fdd0fe474b", "choice_type": "single"} {"question": "Not a pa of epithalamus", "exp": "The epithalamus consists of the habenular trigones on each side of the third ventricle, the pineal body (pineal gland or epiphysis cerebri), and the habenular commissure", "cop": 2, "opa": "Pineal body", "opb": "Geniculate body", "opc": "Trigonum habenulae", "opd": "Posterior commisure", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "68dc9b82-b347-436d-ae33-3df311fe8446", "choice_type": "single"} {"question": "In transverse lie presentation is", "exp": "In transverse lie shoulder presentation is seen", "cop": 4, "opa": "Veex", "opb": "Breech", "opc": "Brow", "opd": "Shoulder", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "7da0f9dd-c922-46b9-9921-340d8f8a9498", "choice_type": "single"} {"question": "Early adolescence age is", "exp": "Adolescence is the stage of transition from childhood to adulthood. Early adolescence ( 10-13yrs) Mid adolescence ( 14-16yrs) Late adolescence (17-19yrs) Ref: Ghai, 9th edition, Chapter 5", "cop": 2, "opa": "8-11 yrs", "opb": "10-13 yrs", "opc": "14-15 yrs", "opd": "16-19 yrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "794972ae-c47d-4d0c-b764-b64c38884aaf", "choice_type": "single"} {"question": "For blood and urine, preservative used is", "exp": "For blood, CSF, vitreous humor and urine, sodium fluoride is the preservative (100mg/10ml) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 404", "cop": 2, "opa": "Sodium chloride", "opb": "Sodium fluoride", "opc": "Sodium acetate", "opd": "Sodium gluconate", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "5880d85e-3801-41c6-853b-7ef4cc1d58a4", "choice_type": "single"} {"question": "Platysma", "exp": null, "cop": 2, "opa": "Compresses the cheeks", "opb": "Draws the angles of mouth downwards", "opc": "Elevates the mandible", "opd": "Helps in mastication", "subject_name": "Anatomy", "topic_name": null, "id": "ac9efae1-62d6-4529-b9d5-fc9ac797365a", "choice_type": "single"} {"question": "Deep perineal pouch contains", "exp": "Deep perineal pouch is the anatomic space enclose by the perineum and located superior to the perineal membrane. the contents are deep transverse perineal muscle, external sphincter muscle of urethra, membranous poion of urethra, bulbourethral gland. Ref - BDC 6e Vol2 pg355", "cop": 4, "opa": "Bulb of penis", "opb": "Crura of penis", "opc": "Bulbospongiosus", "opd": "Membranous urethra", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "d6f388a3-1d3f-4862-941f-65ee58b6dca4", "choice_type": "single"} {"question": "First dorsal interosseous muscle of hand is supplied by", "exp": "Deep branch of ulnar nerve supplies all the 4 dorsal interossei muscles.Superficial branch of ulnar nerve supplies the palmaris brevis muscle.Median nerve supplies the muscles of thenar eminence.Radial nerve have no supply to any intrinsic muscle of hand.B D Chaurasia 7th edition Page no: 182", "cop": 1, "opa": "Deep branch of ulnar nerve", "opb": "Superficial branch of ulnar nerve", "opc": "Median nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "64162c65-9184-4985-98e1-1fa461b90839", "choice_type": "single"} {"question": "Most common cause of death in measles is", "exp": ".", "cop": 1, "opa": "Pneumonia", "opb": "Meningitis", "opc": "Dehydration", "opd": "Encephalitis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "92e4ebb2-1c28-402e-94af-5fc516bfb9a6", "choice_type": "single"} {"question": "Lateral dislocation of patella is prevented by", "exp": "The lateral border provides inseion to vastus lateralis in its upper one-third or half. The medial border provides inseion to the vastus medialis in its upper two-thirds or more. Ref : B D Chaurasia's Humsn Anatomy , seventh edition , volume 2 , pg, no. 22", "cop": 2, "opa": "Rectus femoris", "opb": "Vastus medialis", "opc": "Vastus lateralis", "opd": "Vastus intermedius", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "90811af8-fc0f-4b74-8630-63306c1e545f", "choice_type": "single"} {"question": "The number of laticiferous ducts that open into the nipple is", "exp": "Breast is a compound tubulo-alveolar gland which secretes milk. The gland consists of 15 to 20 lobes. Each lobe is a cluster of alveoli, and is drained by a lactiferous duct. The lactiferous ducts converge towards the nipple and open on it. Near its termination each duct has a dilatation called a lactiferous sinus. Ref - BDC Vol1 6th edition pg 34", "cop": 2, "opa": "0-5", "opb": "15-20", "opc": "35-50", "opd": "50-75", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "3e65d813-102e-4c0f-84d3-eb1d48ea75ef", "choice_type": "single"} {"question": "Management of pancreatic abscess is", "exp": "Sterile and Infected Pancreatic Fluid Collection (Pancreatic Abscess) The presence of acute abdominal fluid during an episode of AP has been described in 30-57% of patients In contrast to pseudocyst and cystic neoplasia of the pancreas, fluid collections are not surrounded or encased by epithelium or fibrotic capsule Treatment is suppoive because most fluid collections will be Spontaneously reabsorbed by the peritoneum Pancreatic Abscess: The presence of fever, elevated WBC count, and abdominal pain suggest infection of this fluid and percutaneous aspiration is confirmatory Percutaneous drainage and IV administration of antibiotics should be instituted if infection (Pancreatic abscess) is present Ref: Sabiston 20th edition Pgno :1529", "cop": 1, "opa": "Needle aspiration", "opb": "Cystogastrostomy", "opc": "USG guided drainage", "opd": "Cystojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7f077ce8-f32e-4926-b46c-64d514d2458b", "choice_type": "single"} {"question": "The lymphatic drainage to central part of the lip is", "exp": "(Sub mental nodes) (207-BDC-3) (769 - Snell 7th)LYMPHATIC DRAINAGE1. LIPS(i) Central part of the lower lip and skin of the chin - Submental nodes(ii) Rest of the lower lip drains to - Sub mandibular nodes2. Cheeks (Buccae) - drain chiefly into submandibular and preauricular nodes and partly also to the buccal and mandibular nodes3. Oral cavity proper(i) Anterior part of the floor of the mouth - sub mental nodes(ii) The gums and the rest of the floor - sub mandibular nodes4. Gums (Gingivae)(i) Upper gum - Submandibular nodes(ii) Anterior part of gum - sub mandibular nodes(iii) Posterior part of gum - submandibular nodes5. Hard palate & Soft palate - The lymphatics drain mostly to the upper deep cervical nodes and partly to the retro pharyngeal nodes* The lymphatic drainage of Tonsil - Jugulodiagastric nodes* Lymph from the forehead and the anterior part of the face drains in to the submandibular lymph nodes. The lateral part of the face including the lateral part of the eyelids is drained by lymph vessels that end in the parotid lymph nodes", "cop": 2, "opa": "Sub mandibular node", "opb": "Sub mental nodes", "opc": "Deep cervical nodes", "opd": "Jugulodiagastric nodes", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "2eb0af00-e11e-4388-b690-f6346d05fca9", "choice_type": "single"} {"question": "Spermatogenesis", "exp": "i.e. (Occurs in seminiferous tubules): (11-12-IBS-Embryology 8th)Spermatozoa are formed in the walls of the seminiferous tubules of the testesSPERMATOGENESIS - formation of gametes (spermatozoa) takes only during the reproductive periods which begins at the age of puberty (12 to 16 years) and continue even though old age* The process of spermatogenesis, including spermiogenesis requires about two months** for its completion.Difference between Spermatogenesis and SpermiogenesisSpermatogenesis is the complete process of formation of a spermatozoon from a spermatogonium. It includes first and second meiotic division and spermiogenesisSpermiogenesis - is the process of transformation of a rounded spermatid into a spermatozoanSERTOLI CELLSSertoli cells are specialized cells within the seminiferous tubules and are involved in the orchestration and coordination of all of the key events in spermatogenesis (including spermiogenesis)Function of Sertoli cells1. Provide support, nutrition to developing spermatozoa2. Protect developing germ cells by forming the blood testes barrier (BTB)3. Secretion of important substances - Androgen binding protein (ABP)*, Inhibin*, Mullerian Inhibiting substance (MIS)*, contain aromatase (CYP)*4. Presence of FSH receptors5. Important role in the final maturation phase of spermiogenesis which is characterized by shedding of excess or residual cytoplasm of the spermatids (Phagocytosis)", "cop": 3, "opa": "Starts at birth", "opb": "Maximum in 37degC", "opc": "Occurs in seminiferous tubules", "opd": "Time required for a spermatogonium to develop into mature spermatozoan is 6 weeks", "subject_name": "Anatomy", "topic_name": "Embryology", "id": "30a12f31-4c50-4bae-9d54-8fa7b1b07186", "choice_type": "single"} {"question": "Nitroblue tetrazolium test is used for", "exp": "Ref, Harrison pg 76 In immunohistochemistry the alkaline phosphatase is often used as a marker, conjugated to an antibody. The colored product can either be of the NBT/BCIP reaction reveals where the antibody is bound, or can be used in immunofluorescence. The NBT/BCIP reaction is also used for colorimetric/spectrophotometric activity assays of oxidoreductases. One application is in activity stainsin gel electrophoresis, such as with the mitochondrial electron transpo chain complexes. Nitro blue tetrazolium is used in a diagnostic test,paicularly for chronic granulomatous disease and other diseases of phagocyte function. When there is an NADPH oxidase defect, the phagocyte is unable to make reactive oxygen species or radicals required for bacterial killing. As a result, bacteria may thrive within the phagocyte. The higher the blue score, the better the cell is at producing reactive oxygen species.", "cop": 1, "opa": "Phagocytes", "opb": "Complement", "opc": "T cell", "opd": "B cell", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "eca87e0b-9be6-4b7e-b225-a07f8a86b9d5", "choice_type": "single"} {"question": "The most common cause of tricuspid regurgitation is secondary to", "exp": "Ref Harrison 19 th ed pg 1548 In at least 80% of cases, TR is secondary to marked dilation of the tricuspid annulus from RV enlargement due to PA hypeension .Functional TR may complicate RV enlargement of any cause, however, including an inferior myocardial infarction (MI) that involves the RV.", "cop": 2, "opa": "Rheumatoid hea disease", "opb": "Dilation of right ventricle", "opc": "Coronary aery disease", "opd": "Endocarditis due to intravenous drug abuse", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "03fb3329-beb4-4aa9-8672-9ffb18c9fdd6", "choice_type": "single"} {"question": "Thoracic duct opens into", "exp": "In the neck, it arches laterally at the level of the transverse process of seventh cervical veebra. Finally it descends in front of the first pa of the left subclan aery and ends by opening into the angle of junction between the left subclan and left internal jugular veins ( both these left subclan and left internal jugular vein drains into left brachiocephalic vein ) Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1, pg. no. 302", "cop": 4, "opa": "Subclan vein", "opb": "Internal jugular vein", "opc": "Right brachiocephalic vein", "opd": "Left brachiocephalic vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "57887867-d4bb-47c7-9be2-5602307101bc", "choice_type": "single"} {"question": "Clergyman&;s knee is due to", "exp": "Subcutaneous Infrapatellar BursaIt lies in front of lower pa of the tibial tuberosity and of the lower pa of the ligamentum patellae.Subcutaneous infrapatellar bursitis is called \"clergyman&;s knee.\"Ref: Chaurasia; Volume 2; 6th edition; Page no: 44", "cop": 2, "opa": "Prepatellar bursitis", "opb": "Subcutaneous Infrapatellar bursitis", "opc": "Deep Infrapatellar bursitis", "opd": "Suprapatellar bursitis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "6732b6f1-fdc4-4fd7-87fa-9e0e2da18665", "choice_type": "single"} {"question": "In corneal reflex efferent is carried by", "exp": null, "cop": 4, "opa": "occulomotor", "opb": "trochlear", "opc": "abducens", "opd": "facial", "subject_name": "Anatomy", "topic_name": null, "id": "93de68fb-1077-4127-8341-58740781330e", "choice_type": "single"} {"question": "Epithelium of cornea is", "exp": "A. i.e. Stratified Squamous non Keratinizing", "cop": 1, "opa": "Stratified squamous non Keratinizing", "opb": "Stratified squamous Keratinizing", "opc": "Collumnar Keratinized", "opd": "Collumnar non Keratinized", "subject_name": "Anatomy", "topic_name": null, "id": "26ec59a9-b350-4626-bbe9-6f0e67dd8652", "choice_type": "single"} {"question": "Most sensitive imaging for ductal carcinoma insitu breast is", "exp": "Screening with MRI is superior to mammography in detecting invasive breast cancer in younger women, where the sensitivity of mammography is low due to presence of mammographically dense breast parenchyma. Ref: Grainger 5th edition Pgno: 1190, 1188", "cop": 2, "opa": "Mammography", "opb": "MRI", "opc": "PET", "opd": "USG", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "c4231efd-b07f-45f5-a21f-b0eedbcfdd87", "choice_type": "single"} {"question": "Ligament with vessels includes", "exp": "(B) Gastro splenic # Gastrosplenic ligament (ligamentum gastrosplenicum or gastrolienal ligament) is part of the greater omentum.> Embryonically the gastrosplenic ligament is derived from the dorsal mesogastrium.> Gastrosplenic ligament is made of peritoneum that connects the greater curvature of stomach with the hilum of the spleen.> Contains: Short gastric vessels & left gastro-epiploic vessels.", "cop": 2, "opa": "Renocolic", "opb": "Gastro splenic", "opc": "Linorenal", "opd": "Phrenicocolic", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "e44dde36-76e3-4f1f-9739-a2594ec06546", "choice_type": "single"} {"question": "Winging of scapula is due to paralysis of (FMGE Dec 2018)", "exp": "Origin-Lateral surfaces of upper 8 to 9 ribs and deep fascia overlying the related intercostal spaces Inseion-Costal surface of medial border of scapula Innervation-long thoracic nerve (C5,6,7) Function-protraction and rotation of scapula, keeps medial border and inferior angle of scapula opposed to thoracic wall Winging of scapula: -As long thoracic nerve passes down the lateral thoracic wall on external surface of serratus anterior muscle just deep to skin & subcutaneous tissue, it is vulnerable to damage. -Loss of function of this muscle cause medial border, paicularly inferior angle of scapula, to elevate away from thoracic wall | (Resulting in) \"winging\" of scapula (on pushing forward with arm) - Normal elevation of arm a no longer possible. Trapezius: supplied by motor spinal pa of accessory nerve (X1); sensory (proprioception) anterior rami of C3 & C4 Function: powerful elevator of scapula, rotates scapula during abduction of humerus above Horizontal. Middle fibers = retract scapula Lower fibers = depress scapula Latissimus dorsi: supplied by thoraco- dorsal nerve (C6, C7, C8) Function: adduction, medial rotation & extension of arm at glenohumeral joint. Pectoralis major: innervated by medial & lateral pectoral nerves.", "cop": 2, "opa": "Trapezius", "opb": "Serratus anterior", "opc": "Latissimus dorsi", "opd": "Pectroralis major", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "f6bc7e03-26c9-44ad-b4ef-a14c9eb505c4", "choice_type": "single"} {"question": "Preganglionic parasympathetic fibres to parotid gland relay at", "exp": "Sensory root by the auriculotemporal nerve. Sympathetic root is by the sympathetic plexus around middle meningeal aery. Secretomotor root is by the lesser petrosal nerve from the tympanic branch of cranial nerve IX. Motor root is by a branch from nerve to medial pterygoid. Ref BDC volume3,6th edition pg 311", "cop": 2, "opa": "Geniculate ganglion", "opb": "Otic ganglion", "opc": "Sub mandibular ganglion", "opd": "Stellate ganglion", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "4dc1789a-d3ef-4de6-90d6-c9a3e005909a", "choice_type": "single"} {"question": "Anti topoisomerase 1 is marker of", "exp": "Ref Robbins 9/e p228 B cell activation also occurs, as indicated by the pres- ence of hypergammaglobulinemia and ANAs. Although there is no evidence that humoral immunity plays a signifi- cant role in the pathogenesis of SS, two of the ANAs are viually unique to this disease and are therefore useful in diagnosis (Table 4-10). One of these, directed against DNA topoisomerase I (anti-Scl 70), is highly specific; it is present in as many as 70% of patients with diffuse scleroderma (and in less than 1% of patients with other connective tissue diseases) and is a marker for the devel- opment of more aggressive disease with pulmonary fibro- sis and peripheral vascular changes. The other ANA is an anticentromere antibody, found in as many as 90% of patients with limited scleroderma (i.e., the CREST syn- drome); it indicates a relatively benign course.", "cop": 1, "opa": "Systemic sclerosis", "opb": "Classical polyaeritis nodosa", "opc": "Nephrotic syndrome", "opd": "Rheumatoid ahritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dc1556e2-6830-490d-b16e-1df2214fb9ed", "choice_type": "single"} {"question": "Bladder develops from", "exp": "Ref Human embryology Inderbier singh 10 th edition Page no 292 The epithelium of urinary bladder devolep from cranial pa of vesicourethral canal (endoderm). The epithelium trigone of baldder is absorbed from absorbed mesonephric ducts(mesoderm) The muscular and serous wall of the oragab are derived fron spalnchnopleuric mesoderm", "cop": 3, "opa": "Ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Neural crest cell", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e96a76fa-49ec-48a4-aecd-b409ef926515", "choice_type": "single"} {"question": "In Wilms tumor the following leads to emergence of resistance to chromotherapy", "exp": "5 percnt of tumors have Anpalsia, defined as the presence of cells with large hyperchromatic pleomprphic nuclei and abnormal mitosis and the presrnc of anapladsia coreltes with p53 mutation", "cop": 3, "opa": "Nehprogenic rests", "opb": "Monoblastic morphology", "opc": "Anpalsia", "opd": "Capsular infiltration", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "bfdd5277-7290-4010-b98d-c3ee7d596ee2", "choice_type": "single"} {"question": "First polar body is extruded at", "exp": "Oogenesis is formation of ovum i.e. female gamete. First polar body is released after LH surge (i.e. at or before ovulation) LH surge occurs 36 hrs before ovulation. LH peak occurs 12 hrs before ovulation. (first polar body released )", "cop": 2, "opa": "Menstruation", "opb": "Ovulation", "opc": "Feilization", "opd": "Menopause", "subject_name": "Anatomy", "topic_name": "Introduction and gametogenesis.", "id": "cce8dee5-9799-4cec-9d72-4f751592f003", "choice_type": "single"} {"question": "Drug induced poal hypeension is seen with", "exp": "Vitamin A induced Hepatotoxicity Normal dose of vitamin A are not associated with liver injury or liver test abnormalities, but higher doses can be toxic Mechanism of injury : Excess Vitamin A is stored in stellate cells in the liver and accumulation can lead to their activation and hyperophy, excess collagen production, fibrosis and liver injury Serum bilirubin is typically only mildly elevated Liver biopsy is diagnostic Ref: Internet sources", "cop": 1, "opa": "Vitamin A toxicity", "opb": "Methotrexate", "opc": "Aldomet", "opd": "Hydatid cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f8f4b383-b8fd-4a9d-8d89-a1b8639d060a", "choice_type": "single"} {"question": "Milwakulee classification is used for", "exp": "Modified Milwaukee classification is used for Biliary sphincter of oddi classification Types Sphincter of oddi stenosis : Also known as papillitis Benign intrinsic obstruction of the CBD outlet. Sphincter of oddi dyskinesis : It is an intermittent functional Blockage of the high pressure zone of the sphincter. Basal pressure is elevated, but administration of smooth muscles relaxants(nitrates) causes decrease of the basal sphincter pressure in functional dyskinesis Ref: Sabiston 20th edition Pgno :1497", "cop": 1, "opa": "Sphincter of oddi dysfunction", "opb": "Abnormal pancreaticobiliary duct junction", "opc": "Acute pancreatitis", "opd": "Chronic pancreatitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f33c9f88-b1f3-49c5-849d-76e4ec57f91a", "choice_type": "single"} {"question": "Sclerotherapy failure is defined as", "exp": "Failure of endoscopic treatment is declared when two sessions fail to control hemorrhage Ref: Sabiston 20th edition", "cop": 1, "opa": "Unresponsiveness to consecutive 2 energy sclerotherapies", "opb": "Unresponsiveness to consecutive 3 energy sclerotherapies", "opc": "Remnant bleeding even after sclerotherapy for successive 2 hospital admissions", "opd": "Failure to heal after a single treatment", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "049c0cfa-6736-4963-b9a7-d97790493bd0", "choice_type": "single"} {"question": "Structure NOT passing through Aortic opening of diaphragm", "exp": "(D) VagusVena Cava (8 letters) - Passes through the diaphragm at T8.Oesophagus (10 letters) - Passes through the diaphragm at T10.Aortic Hiatus (12 letters) - Passes through the diaphragm at T12.OPENINGS THROUGH THE DIAPHRAGM & THEIR CONTENTSDescriptionVertebral levelContentsCava! opening lies in central tendon of DiaphragmT8 (to the right side of the median plane)Caval opening passes through the central tendon of the diaphragm. Contains Inferior vena cava, & some branches of the Right Phrenic nerve.Esophageal hiatuslies in Masseter part of diaphragmT10 (to the of the median plane)Esophageal hiatus is situated in the posterior part of the diaphragm, located slightly left of the central tendon through the muscular sling of the right crus of the diaphragm.Oesophagus & anterior & posterior Vagal trunks.Lymphatics from the lower third of the esophagusAortic hiatus OsseoaponeuroticT12 (in the median plane)Aortic hiatus is in the posterior part of the diaphragm, between the left & right crus.Aorta, Azygos vein & Thoracic duct.Two lesser apertures of right crusGreater & Lesser Right splanchnic nervesTwo lesser apertures of left crusGreater & Lesser Left Splanchnic nerves & Hemiazygos veinBehind the diaphragm, under the medial lumbocostal archSympathetic trunkAreolar tissue between the sternal & costal parts (Foramina of Morgagni)Superior epigastric branch of the internal thoracic artery & some lymphatics from the abdominal wall & convex surface of the liverAreolar tissue between the fibers springing from the medial & lateral lumbocostal archesThis interval is less constant; when this interval exists, the upper & back part of the kidney is separated from the pleura by areolar tissue only.OTHER STRUCTURES PASSING THROUGH DIAPHRAGMSplanchnic nerves - which pierce the cruraInferior hemiazygos - Vein which pierce the left crus.Psoas major Muscle.Sympathetic trunk (pass deep to the medial arcuate ligament).Quadratus lumborum.Subcostal Nerve, Vessels (pass deep to the lateral arcuate ligamentClinical Importance:Lumbocostal triangle or Bochdalek's foramen, Diaphragmatic hernia, Diaphragmatic paralysis, Congenital eventration of diaphragm, Hiccup.Aortic opening (Aortic hiatus) is one the three major apertures through the diaphragm & lies at the level of T12.A number of structures pass through the aortic hiatus: aorta, azygos vein, thoracic duct, greater splanchnic nerve.", "cop": 4, "opa": "Azygos vein", "opb": "Aorta", "opc": "Thoracic duct", "opd": "Vagus", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "2e171e43-c4d5-46d7-9d5d-fd7266d333d5", "choice_type": "single"} {"question": "This finding is seen in", "exp": ".", "cop": 3, "opa": "Drowning", "opb": "Amyloidosis", "opc": "Putrefaction", "opd": "Mummification", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d680fa91-7000-4364-84ed-8e828387c331", "choice_type": "single"} {"question": "Each lateral ventricle opens into the 3rd ventricle through", "exp": "Cavities within brain and spinal cord:\na) The cerebrum contains a median cavity, the third ventricle and two lateral ventricles, one in each hemisphere.\nb) Each lateral ventricle opens into the 3rd ventricle through interventricular foramen or foramen of  monro.\nc) The third ventricle opens into the 4th ventricle  (i.e., cavity of hind brain) through the cerebral aqueduct.\nd) The 4th ventricle communicates with subarachnoid space through two lateral foramen or foramen of luschka and a medial foramen or foramen of magendi.", "cop": 1, "opa": "Foramen of Monro", "opb": "Lateral foramen", "opc": "Foramen of luschka", "opd": "Foramen of magendi", "subject_name": "Anatomy", "topic_name": null, "id": "1f06f343-4703-4dca-bf0f-70f42e6edc64", "choice_type": "single"} {"question": "Medical treatment of acute pancreatitis includes", "exp": "Treatment Cornerstone of the treatment : Aggressive fluid resuscitation using isotonic crystalloid solution with supplementary oxygen Narcotics are usually preferred, especially Buprenophine >Morphine as analgesics In acute pancreatitis medical treatment Analgesics (Buprenophine, meperidine) IV fluids and colloids No oral alimentation Treatment of hypocalcaemia, if symptomatic Antibiotics Ref: Sabiston 20th edition Pgno :1524-1528", "cop": 1, "opa": "Calcium", "opb": "Glucagon", "opc": "Aprotinin", "opd": "Cholestyramine", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "36c3d86f-89e1-4175-9cc8-619012244b2f", "choice_type": "single"} {"question": "Awareness during anaesthesia can be assessed by", "exp": ".", "cop": 2, "opa": "a) ETCO2", "opb": "b) BIS", "opc": "c) AERIAL B.P", "opd": "d) NEUROMASCULAR MONITOR", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "49756271-71e9-4e75-8834-0419813d255c", "choice_type": "single"} {"question": "Mi's expression of the following homeobox genes alters the position of the forelimbs during development", "exp": "The carnival limit of expression of HOX B8 is at the carnival border of the forelimbs, and the mid - expression of this gene alters the position of these limbs Position of the limbs along the craniocaudal axis in the flank regions of the embryo is regulated by the HOX genes expressed along this axis. Ref: Gray's 39e/p-1289", "cop": 2, "opa": "HOX A7", "opb": "HOX B8", "opc": "HOX C9", "opd": "HOX D 10", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9b47ec6f-e2f2-48bd-8c8f-5edcec633a6c", "choice_type": "single"} {"question": "The total number of ligamentuni denticulatum lies on side of spinal cord are", "exp": "(D) 40-42 # Ligamentum denticulatum is a flat, fibrous sheet which lies on each side of the spinal cord between the ventral and dorsal spinal roots. Its medial border is continuous with the subpial connective tissue of the cord and its lateral border forms a series of triangular processes, the apices of which are fixed at intervals to the dura mater. There are usually 21 processes on each side. The first crosses behind the vertebral artery where it is attached to the dura mater, and is separated by the artery from the first cervical ventral root. Its site of attachment to the dura mater is above the rim of the foramen magnum, just behind the hypoglossal nerve: Spinal accessory nerve ascends on its posterior aspect. Last of the dentate ligaments lies between the exiting twelfth thoracic and first lumbar spinal nerves and is a narrow, oblique band which descends laterally from the conus medullaris. Changes in the form and position of the dentate ligaments during spinal movements have been demonstrated by cine- radiography.", "cop": 4, "opa": "10--12", "opb": "20 -- 22", "opc": "30 -- 32", "opd": "40 -- 42", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "b4704586-fb50-4696-9224-bcf1911e888d", "choice_type": "single"} {"question": "Most impoant pathophysiological cause of GERD is", "exp": "\"Transient LES relaxations account for at least 90% of reflux in normal subjects or GERD patients without a hiatus hernia\"- Harrison Transient lower oesophagal sphincter relaxations account for essentially all reflux events in individuals with a normal LES pressure at the time of reflux. Pathogenesis of gastroesophageal reflux disease (GERD) The primary event in the pathogenesis of gastroesophageal reflux disease (GERD) is a movement of gastric juice from the stomach into the oesophagus. The three dominant pathophysiologic mechanisms causing gastroesophageal junction incompetence are: Transient lower esophageal sphincter relaxations (tLESRs) A hypotensive lower oesophagal sphincter (LES) Anatomic disruption of the gastroesophageal junction, often associated with a hiatal hernia The latest concept is that the dominant mechanism varies as a function of disease severity with tLESRs predominating with mild disease and mechanisms associated with a hiatus hernia and/or a weak sphincter predominating with more severe disease Transient LES relaxations are different from swallow-induced LES relaxation: tLESRs occur without an associated pharyngeal contraction, are unaccompanied by oesophagal peristalsis, and persist for longer periods (>10 sec) than do swallow-induced LES relaxations. tLESRs are the physiological mechanism of belching. Ref : Harrison 18/e p2433", "cop": 2, "opa": "Hiatus hernia", "opb": "Transient LES relaxation", "opc": "LES hypotension", "opd": "Inadequate esophageal clearance", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "04af8bda-8f27-4d95-8a56-17f80158d94d", "choice_type": "single"} {"question": "Child criteria doesnt include", "exp": "Variables in Child-Turcotte-Pugh scoring system Serum albumin Bilirubin Prothrombin time Ascites Encephalopathy Ref: Sabiston 20th edition Pgno : 1436", "cop": 2, "opa": "Encephalopathy", "opb": "ALT", "opc": "Ascites", "opd": "Albumin", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "165851d6-7384-4ba6-b3de-0b316916f412", "choice_type": "single"} {"question": "Earlier site of bone involvement in Hematogenous osteomyelitis", "exp": "Metaphysis of long bone is the earliest and most common site involved Refer Maheshwari 6th/e p 168", "cop": 1, "opa": "Metaphysis", "opb": "Diaphysis", "opc": "Epiphysis", "opd": "Point of entry of nutrient aery", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "d957e323-127d-4b2d-9b4c-b98e90befafa", "choice_type": "single"} {"question": "Posterior columns sensations in lower limbs are lost in", "exp": "Refer KDT 6/e p589 Deficiency of vitamin B12 leads to Megaloblastic anemia which is indistinguishable from folic acid deficiency Deficiency also have manifestations related to loss of myelin like Subacute combined degeneration of spinal cord", "cop": 2, "opa": "Vitamin A deficiency", "opb": "Vitamin B12 deficiency", "opc": "Vitamin C deficiency", "opd": "Vitamin D deficiency", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "63c991da-75b3-4032-9eae-5c686f64de4d", "choice_type": "single"} {"question": "Polyribosyl ribitol phosphate PRP antigen is present in the capsule of H. influenzae", "exp": "Capsular polysaccharide of serotype b has PRP antigen that is also used in vaccine preparation because of it's immunogenic propey.", "cop": 2, "opa": "Serotype a", "opb": "Serotype b", "opc": "Serotype c", "opd": "Serotype d", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "4834c898-2f76-4a91-af71-197fdd62e0fc", "choice_type": "single"} {"question": "Only nerve that originates from the dorsal surface of the brain stem is", "exp": null, "cop": 1, "opa": "Trochlear", "opb": "Occulomotor", "opc": "Vagus", "opd": "Abducent", "subject_name": "Anatomy", "topic_name": null, "id": "d6a73566-d855-4a51-8b1c-9696be76b26a", "choice_type": "single"} {"question": "Yoke muscle pair", "exp": "Yoke muscles are the primary muscles in each eye that accomplish a given version (eg, for right gaze, the right lateral rectus and left medial rectus muscles). Each extraocular muscle has a yoke muscle in the opposite eye to accomplish versions into each gaze position. By the Herring law, yoke muscles receive equal and simultaneous innervation. The magnitude of innervation is determined by the fixating eye, which means that the angle of detion between eyes (strabismus) may vary depending on which eye is fixating. The primary detion is misalignment, with the normal eye fixating. If the paretic eye fixates, the ensuing secondary detion is typically larger than the primary detion. Ref - medscape.com", "cop": 3, "opa": "Rt IR + Rt SR", "opb": "Rt LR + Rt MR", "opc": "Rt LR + Lt MR", "opd": "Lt LR + Lt MR", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "99dda533-dbf7-4faf-8c23-88b21534e5c9", "choice_type": "single"} {"question": "Epithelial lining of the vagina is", "exp": "The lining of orifices is stratified squamous epithelium. In moist areas it is non-keratinised.Examples of non-keratinized stratified squamous epithelium include corneal epithelium, lining mucosa of the oral cavity, esophagus, anal canal, ectocervix, vagina and the internal poion of the lips.Reference: Chaurasia; 6th edition", "cop": 1, "opa": "Stratified squamous non-keratinised", "opb": "Stratified squamous keratinised", "opc": "Columnar", "opd": "Cuboidal", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fa5bfb83-5649-4731-8719-ab88e5f4bd99", "choice_type": "single"} {"question": "Dangerous area of face", "exp": "The facial vein communicates with the cavernous sinus through emissary veins infections from the face can spread in a retrograde direction and cause thrombosis of the cavernous sinus. This is especially likely to occur in the presence of infection in the upper lip and in the lower pa of the nose. This area is therefore called dangerous area of the face. REF.BDC 6th edition volume 3 pg no 73", "cop": 1, "opa": "Upper lip middle 1/3rd", "opb": "Lower lip middle 1/3rd", "opc": "Lower lip lateral pa", "opd": "Periorbital area", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "3c4ad022-88ef-4fa6-b6a0-21c7d840e4d1", "choice_type": "single"} {"question": "Lymphatic drainage of ovary", "exp": "The left ovarian vein drains into the left renal vein, and the right ovarian vein empties directly into the inferior vena cava. Supply is through the ovarian, hypogastric, and aoic plexuses. Lymph drainage of the ovary is primarily to the lateral aoic nodes; however, the iliac nodes are also involved. Ref - BDC 6e vol2 pg384", "cop": 4, "opa": "Deep inguinal", "opb": "Superficial inguinal", "opc": "Obturator", "opd": "Paraaoic", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "d0a15a05-8a91-468a-a280-eb6c43a4cbbf", "choice_type": "single"} {"question": "Most common metabolic disturbance of cirrhosis is", "exp": "Electrolyte abnormalities in Cirrhosis Hyponatremia Hypokalaemia Metabolic alkalosis (precipitate PNH) Ref: Sabiston 20th edition Pgno :565", "cop": 2, "opa": "Metabolic acidosis", "opb": "Metabolic alkalosis", "opc": "Respiratory acidosis", "opd": "Respiratory alkalosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3c93a75d-bce1-4182-8171-22c8a35595a8", "choice_type": "single"} {"question": "Following appearance is noted in", "exp": ".", "cop": 3, "opa": "CVC spleen", "opb": "CVC lung", "opc": "CVC liver", "opd": "CVC adrenal", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d1e7b180-22c9-4250-bba0-597192d9cb26", "choice_type": "single"} {"question": "Cranial nerves III, IV, V, VI lesions are associated with", "exp": "(D) Cavernous sinus# Each Cavernous Sinus (one for each hemisphere of the brain) contains the following:> Vertically, from superior to inferior (within the lateral wall of the sinus).> Oculomotor nerve (CN III)> Trochlear nerve (CN IV)> Ophthalmic nerve, the V1 branch of the trigeminal nerve (CN V).> Maxillary nerve, the V2 branch of CN V> Unlike the nerves listed above, the abducens nerve (CN VI) does not run within the lateral wall of the cavernous sinus; rather it runs through the middle of the sinus alongside the internal carotid artery.> Horizontally, from medial to lateral> Internal carotid artery and sympathetic plexus.", "cop": 4, "opa": "Sphenoparietal sinus", "opb": "Occipital sinus", "opc": "Occipital sinus", "opd": "Cavernous sinus", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "2b8aa334-584c-407a-b442-5526f1a1ccb2", "choice_type": "single"} {"question": "Nutrient artery to Femur is a branch of", "exp": "Femur gets its nutrient artery from 2nd perforating Branch arising from profunda femoris artery.", "cop": 3, "opa": "Inferior gluteal Artery", "opb": "1st perforating Branch of profunda femoris artery", "opc": "2nd perforating Branch of profunda femoris artery", "opd": "Lateral circumflex femoral artery", "subject_name": "Anatomy", "topic_name": null, "id": "c396af37-6e38-4458-909a-7e01e91f617b", "choice_type": "single"} {"question": "Internal spermatic fascia is derived from", "exp": "The transverse fascia is a thin aponeurotic membrane which lies between the inner surface of the transverse abdominal muscle and the parietal peritoneum.It forms pa of the general layer of fascia lining the abdominal parietes, and is directly continuous with the iliac fassia, internal spermatic and pelvic fascia.In the inguinal region, the transverse fascia is thick and dense in structure and is joined by fibers from the aponeurosis of the transverse abdominal. ref - BDC 6e vol2 pg 223,226", "cop": 1, "opa": "Fascia transversalis", "opb": "External oblique aponeurosis", "opc": "Internal oblique aponeurosis", "opd": "Transversus abdominis", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "25a0299f-f5cf-4a29-9ad7-4214efa11610", "choice_type": "single"} {"question": "Fracture of the neck of fifth metacarpal occurs in", "exp": "Fracture of the neck of fifth metacarpal occurs usually due to striking the closed hand against a firm surface(Boxer's fracture) occurs in boxers. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 179", "cop": 4, "opa": "Hangman's fracture", "opb": "Jefferson's fracture", "opc": "Greenstick fracture", "opd": "Boxer's fracture", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "9ca0f832-703b-4a74-842c-4304cd28b8b0", "choice_type": "single"} {"question": "Flexion of knee joint is caused by", "exp": "KNEE JOINT:- Largest and most complex joint of the body.Fusion of 3 joints(lateral femorotibial, medial femorotibial, and femoropatellar) in one.Type: condylar synol joint. Movements:-Flexion,extension,medial and lateral rotation.Flexion and extension takes place in upper compament of the joint, above the menisci. They differ from ordinary hinge movements-The transverse axis around which these movements takes place is not fixed. During extension, the axis moves forward and upwards, and in the reverse direction during flexion.These are accompanied by rotation. Medial rotation of the femur occurs during the last 30 degrees of extension, and lateral rotation of the femur occurs during initial stages of flexion. When feet is on the ground, while standing erect, medial rotation of femur occurs during the last 30 degrees of extension as in \" attention \" by the vastus medialis.During the position of \"stand at ease\", there is lateral rotation of femur, during initial stages of flexion by the popliteus. Muscles involved:-1. Flexion- Biceps femoris Semitendinosus Semimembranosus 2. Extension-Quadriceps femoris. {Reference: BDC 6E pg no. 145}", "cop": 3, "opa": "Rectus femoris", "opb": "Vastus medialis", "opc": "Hamstrings", "opd": "Vastus lateralis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "be150a60-26a4-4968-a8b4-c95cca2a9f26", "choice_type": "single"} {"question": "The tongue is formed from", "exp": "The tongue has contributions from all pharyngeal arches which changes with time.\nThe tongue initially begins as swelling rostral to foramen cecum, the median\ntongue bud.\nArch 1 - oral part of tongue (anterior 3/2)\nArch 2 - initial contribution to surface is lost\nArch 3 - pharyngeal part of tongue (posterior 1/3)\nArch 4 - epiglottis and adjacent regions", "cop": 4, "opa": "I,II,V branchial arches", "opb": "I,III,V branchial arches", "opc": "I,III,IV branchial arches", "opd": "I,II,III,IV branchial arches", "subject_name": "Anatomy", "topic_name": null, "id": "5bb231c6-909d-4c77-9727-12034cae23f3", "choice_type": "single"} {"question": "Lack of fusion of maxillary and medial nasal process results in", "exp": "Human embryology Tenth edition Inderbir Singh Page no 160 When one or both maxillary process don't fuse with medial nasal process give rise to defect in upper lip", "cop": 4, "opa": "Upper hare lip", "opb": "Lower hare lip", "opc": "Cleft palate", "opd": "Cleft palate and cleft lip", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9632c78f-4909-4097-963d-6578bbfe4675", "choice_type": "single"} {"question": "Following tarsal bone is devoid of muscular attachment", "exp": "TALUS:- Second largest tarsal bone.Head, neck, and body. Tibia above and calcaneum below, Attachments:-Devoid of muscular attachment. Numerous ligaments attached to it because it takes pa in three joints- ankle, talocalcaneal, and talonavicular.Neck:- Capsular ligament of ankle joint.Dorsal talonavicular Interosseus talocalcanean and cervical ligament.Anterior talofibular ligament. Medial surface of body:- deep fibres of deltoid. Medial tubercle - superficial fibres of deltoid ligament. Groove on posterior surface lodges flexor hallucis tendon. Posterior talofibular ligament attached to posterior process.Plantar border: posterior talocalcanean ligament. {Reference: BDC 6E pg no. 30}", "cop": 1, "opa": "Talus", "opb": "Navicular", "opc": "Cuboid", "opd": "Medial cuneiform", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "4e466817-a7c4-432e-ba2d-2cda7cfaba3b", "choice_type": "single"} {"question": "The most commonest cause of acute cor pulmonale is", "exp": "Ref Harrison 19 th ed pg 1454 ,1505 The most commonest cause of acute cor pulmonale is pulmonary thromboembolism. The most common cause of chronic cor pulmonale is COPD.", "cop": 2, "opa": "Pneumonia", "opb": "Pulmonary thromboembolism", "opc": "COPD", "opd": "primary spontaneous pneumothorax", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "8cb2fdf1-d678-4e16-b61b-58cb6d84fb8c", "choice_type": "single"} {"question": "Most common splenic cyst is", "exp": ".", "cop": 2, "opa": "Dermoid cyst", "opb": "Hydatid cyst", "opc": "Pseudo cyst", "opd": "Lymphangioma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "87b4edca-953d-468b-bbd9-8335ea0704f3", "choice_type": "single"} {"question": "The following growth indicator may appear relatively normal in patients with chronic severe malnutrition", "exp": "Height-for-age (or length-for-age for children <2 yr) is a measure of linear growth, and a deficit represents the cumulative impact of adverse events, usually in the first 1,000 days from conception, that result in stunting, or chronic malnutrition. A low height-for-age typically reflects socioeconomic disadvantage. A low weight-for-height, or wasting, usually indicates acute malnutrition. Conversely, a high weight-for-height indicates overweight. Weight-for-age is the most commonly used index of nutritional status, although a low value has limited clinical significance as it does not differentiate between wasting and stunting. Weight-for-age has the advantage of being somewhat easier to measure than indices that require height measurements. In humanitarian emergencies and some field settings, mid-upper arm circumference is used for screening wasted children", "cop": 1, "opa": "weight for height", "opb": "height for age", "opc": "weight for age", "opd": "head circumference", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3884afe1-287e-4dd5-9567-e0d6b4287bc7", "choice_type": "single"} {"question": "Infection of index finger spread to", "exp": "Infection of thumb and index finger spreads to thenar space. Infection from middle, ring and little finger spreads to midpalmar space.", "cop": 3, "opa": "Mid-palmar space", "opb": "Radial bursa", "opc": "Thenar space", "opd": "Dorsum of hand", "subject_name": "Anatomy", "topic_name": null, "id": "d67864fb-6034-453a-b714-a6b163291643", "choice_type": "single"} {"question": "Most potent stimulator of naive T cell is", "exp": "Ref Robbins 9/e p191 Naive T cells leave the thymus and home to secondary lymphoid organs. Dendritic cells are the most potent activators of naive T cells. DCs carry antigen from the periphery to the draining lymph nodes. ... CD28 signaling provides \"Signal 2\" to T cells and is necessary for T cell activation.", "cop": 1, "opa": "Mature dendritic cells", "opb": "Follicular dendritic cells", "opc": "Macrophage", "opd": "Bcell", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e1ded635-eccd-4b17-a82e-d3b313b5ed1c", "choice_type": "single"} {"question": "cove sensitization is a type of", "exp": "In cove sensitization also called as imagined punishment, the individual who wants to quit alcohol will be asked to think about adverse consequences of taking alcohol like getting arrested for drunken driving or facing a accident underintoxicated state. He would be told to dream as if if he is drunk and lies intoxicated in the road and has to be brought back to the home by family members where he will be given lot of advice from neighbours and there would be a loss of respect. While these imagined exposure the patient feels bad and makes sure thet he should quit alcohol and his thoughts ahgainst alcohol increases. Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 2, "opa": "analytic therapy", "opb": "behavioral therapy", "opc": "mindfulness therapy", "opd": "dynamic therapy", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "1dbaac54-8789-4189-87d5-03d9e435e837", "choice_type": "single"} {"question": "Poor prognostic factor in patient with acute pancreatitis u", "exp": "Ranson's prognostic criteria for Non-gallstone pancreatitis At admission Age >55 years WBC >16000 cells/mm3 Blood glucose >200mg/dl Serum LDH>350IU/L AST >250 U/L During initial 48hours Hematocrit fall >10 percentage points. BUN elevation >5mg/dl Serum calcium fall to <8mg/dl Aerial pO2v<60 mmHg Base deficit >4mEq/L Estimated fluid sequestration >6 litres Ranson's prognostic criteria for gallstone pancreatitis At admission Age >70 years WBC >18000 cells/mm Glucose >220mg/dl Serum LDH >400IU/L AST >250U/L During initial 48 hours Hematocrit fall >10 percentage points BUN elevation >2mg/dl Serum calcium fall to <8mg/dl Base deficit >5nEq/L Aerial pO2<60 mmHg Estimated fluid sequestration >4 litres Patients with one or two criteria have a predicted moality of less than 1%, with three criteria (10%) of four criteria (15%) with more than seven criteria 50% Ref: Sabiston 20th edition Pgno : 1527-1528", "cop": 1, "opa": "Leucocytosis >20000/ul", "opb": "Decreased serum amylase", "opc": "Decreased serum lipase", "opd": "Diastolic BP >90mmHg", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ffa5cb0a-2c44-4ef8-a6d2-4ab7c7c2de3b", "choice_type": "single"} {"question": "Pisiform bone aiculates with", "exp": "Pisiform aiculates only with Triquetral. Triquetral aiculates with Pisiform, lunate, hamate and aicular disc of Inferior radioulnar joint. B D Chaurasia 7th edition Page no: 27", "cop": 1, "opa": "Triquetral", "opb": "Lunate", "opc": "Scaphoid", "opd": "Trapezoid", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e58ff3ad-b8bc-4afc-a636-e69845358369", "choice_type": "single"} {"question": "In Non hemolytic jaundice, urobilinogen is seen in", "exp": ".", "cop": 4, "opa": "Obstructive jaundice", "opb": "Hepatic fibrosis", "opc": "Fatty liver", "opd": "Infective Hepatitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "08044f87-3820-48d2-bc11-40e732f38424", "choice_type": "single"} {"question": "In some kidney transplants Hyperacute graft rejection is seen . It is due to", "exp": "Ref - Bailey and love 25 e p1410", "cop": 4, "opa": "B lymphocytes", "opb": "T cells", "opc": "CD+4 cells", "opd": "Preformed antibodies", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e69c888f-499f-4ad2-8b8b-27ff67e00e8e", "choice_type": "single"} {"question": "Cleft of upper lip is formed due to failure", "exp": null, "cop": 4, "opa": "Failure of fusion of maxillary process to mandibular process", "opb": "Medial nasal and two mandibular process", "opc": "Medial nasal and lateral nasal process", "opd": "Medial nasal and maxillary process", "subject_name": "Anatomy", "topic_name": null, "id": "5880deca-fe7c-4d32-93ee-b155e8abc97a", "choice_type": "single"} {"question": "Most common site of medulloblastoma is", "exp": "Medulloblastoma is a cancerous tumor--also called cerebellar primitive neuroectodermal tumor (PNET)--that stas in the region of the brain at the base of the skull, called the posterior fossa. These tumors tend to spread to other pas of the brain and to the spinal cord. Refer Robbins page no 1312", "cop": 2, "opa": "Medulla", "opb": "Cerebellum", "opc": "Cerebrum", "opd": "Pineal gland", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "5cfc95f7-47da-4ac1-8c7b-11e3410a802a", "choice_type": "single"} {"question": "Poland Syndrome is", "exp": "Poland Syndrome is Congenital absence of Pectoralis major", "cop": 4, "opa": "Congenital absence of Pectoralis minor", "opb": "Acquired Weakness and disuse atrophy of Pectoralis minor", "opc": "Acquired Weakness and disuse atrophy of Pectoralis major", "opd": "Congenital absence of Pectoralis major", "subject_name": "Anatomy", "topic_name": null, "id": "d8de3a6a-7a3f-4516-9594-fe49b23bee60", "choice_type": "single"} {"question": "Not a direct branch of aoa", "exp": "ARCH OF AOA BRANCHES Arch of aoa is the continuation of the ascending aoa.It is situated in the superior mediastinum behind the lower half of the manubrium sterni. BRANCHES 1.Brachiocephalic aery which divides into the right common carotid and right subclan aeries. 2.Left common carotid aery 3.Left suclan aery REF.BDC VOL.1,FIFTH EDITION", "cop": 4, "opa": "Left common carotid aery", "opb": "Left subclan aery", "opc": "Brachiocephalic trunk", "opd": "Right common carotid aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "626c1a32-e102-40b4-86b1-917767f4fe84", "choice_type": "single"} {"question": "Coeliac plexus is located", "exp": "The celiac plexus or coeliac plexus, also known as the solar plexus because of its radiating nerve fibers, is a complex network of nerves (a nerve plexus) located in the abdomen, near where the celiac trunk, superior mesenteric aery, and renal aeries branch from the abdominal aoa. ref - sciencedirect.com", "cop": 3, "opa": "Anterolateral & around the aoa", "opb": "Posterolateral & around the aoa", "opc": "Anteromedial to lumbar sympathetic chain", "opd": "Posterolateral to lumbar sympathetic chain", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "95cd5b2a-9c5d-4d4e-ba52-8bdfaeccea81", "choice_type": "single"} {"question": "The common peroneal nerve can be rolled against the following pa of the fibula", "exp": "COMMON PERONEAL NERVE:- Smaller terminal branch of sciatic nerve.Root value: dorsal division of ventral rami of L4,L5,S1,S2.Beginning: begins in back of thigh as a smaller subdivision of the sciatic nerve. Course:lies in upper lateral pa of popliteal fossa. It turns around the lateral surface of the fibula. Then it lies in the substance of peroneus longus muscle.Terminates by dividing into two terminal branches- superficial and deep peroneal. Commonest nerve to be paralysed.Causes of injury:1. Fracture neck of fibula.2. Lathi injury on lateral side of knee joint.3. Due to plaster on leg.- nerve get compressed between hard plaster and neck of fibula.To prevent this cotton must be placed on the upper lateral side of the leg. {Reference: BDC 6E}", "cop": 3, "opa": "Styloid process", "opb": "Head", "opc": "Neck", "opd": "Shaft", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "449bce5b-81af-4611-9c21-21d66c4fd8c3", "choice_type": "single"} {"question": "In management of thyroglossal cyst", "exp": "Thyroglossal cyst is managed by Sistrunk operation in which the cyst is completely excised along with the thyroglossal tract. Since the thyroglossal tract is intimately related to the hyoid bone, the central poion of the hyoid bone is also removed. Ref : S. Das Op. Surgery 4/e p201", "cop": 3, "opa": "Nodes of neck are removed", "opb": "Sternocleidomastoid muscle is dissected", "opc": "Central poion of thyroid is excised", "opd": "Subtotal thyroidectomy is done", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f88788b6-8fcc-4f26-b53a-fa9ef975d6c9", "choice_type": "single"} {"question": "Skin cancers develop due to sun light exposure induced by", "exp": "Ref Robbins 7/e p323,9/e p324 Radiation, whatever its source (UV rays of sunlight, x-rays, nuclear fission, radionuclides) is an established carcinogen. Unprotected miners of radioactive elements have a 10-fold increased incidence of lung cancers. Follow-up study of survivors of the atomic bombs dropped on Hiroshima and Nagasaki disclosed a markedly increased incidence of leukemia--principally myelogenous leukemias--after an average latent period of about 7 years, as well as increased moality rates for thyroid, breast, colon, and lung carcino- mas. The nuclear power accident at Chernobyl in the former Soviet Union continues to exact its toll in the form of high cancer incidence in the surrounding areas. More recently, it is feared that radiation release from a nuclear power plant in Japan damaged by a massive eahquake and tsunami will result in significantly increased cancer incidence in the surrounding geographic areas. Therapeutic irradiation of the head and neck can give rise to papillary thyroid cancers years later. The oncogenic propeies of ionizing radiation are related to its mutagenic effects; it causes chromosome breakage, translocations, and, less frequently, point mutations. Biologically, double- stranded DNA breaks seem to be the most impoant form of DNA damage caused by radiation. The oncogenic effect of UV rays merits special mention because it highlights the impoance of DNA repair in car- cinogenesis. Natural UV radiation derived from the sun can cause skin cancers (melanomas, squamous cell carcino- mas, and basal cell carcinomas). At greatest risk are fair- skinned people who live in locales such as Australia and New Zealand that receive a great deal of sunlight. Non- melanoma skin cancers are associated with total cumula- tive exposure to UV radiation, whereas melanomas are associated with intense intermittent exposure--as occurs with sunbathing. UV light has several biologic effects on cells. Of paicular relevance to carcinogenesis is the ability to damage DNA by forming pyrimidine dimers This type of DNA damage is repaired by the nucleotide excision repair pathway. With extensive exposure to UV light, the repair systems may be overwhelmed, and skin cancer results. As mentioned earlier, patients with the inherited disease xeroderma pigmentosum have a defect in the nucleotide excision repair pathway. As expected, there is a greatly increased predisposition to skin cancers in this disorder.", "cop": 2, "opa": "UV A rays", "opb": "UV B rays", "opc": "UV C rays", "opd": "UV D rays", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a7ccdcb3-cda6-42d9-b2d1-e69149cd48a4", "choice_type": "single"} {"question": "Morula reaches uterus at", "exp": "Morula is 16 cell structure and reaches uterus by 4th day of feilisation. Soon divisions occurs and blastocyst is formed which is 64 celled structure by day 6.", "cop": 2, "opa": "3rd day after feilization", "opb": "4th day after feilization", "opc": "6th day after feilization", "opd": "8th day after feilization", "subject_name": "Anatomy", "topic_name": "Introduction and gametogenesis.", "id": "a4ae7be1-0c78-4dc0-bf40-9f43580b670d", "choice_type": "single"} {"question": "Tubocurarine action is easily reversed by", "exp": ".", "cop": 2, "opa": "Atropine", "opb": "Neostigmine", "opc": "Edrophonium", "opd": "Galamin", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3190702f-c10d-4b69-9306-49931fde01b8", "choice_type": "single"} {"question": "depression with reverse vegetative symptoms is treated with MAOIMAOI", "exp": "MAOI * IMPOANCE First class of antidepressant drugs that were introduced * MECHANISM There are three monoamines namely dopamine, adrenaline and serotonin. These mon amines are degraded by monoamine oxidase. MAOI inhibit this enzyme and acts increasing monoamines * DRUGS Phenelezine Tranylcipromine * USE ATYPICAL DEPRESSION, depression with reverse vegetative symptoms * SIDE EFFECTS Hypeensive crisis Cheese reaction When a patient on MAOI takes tyramine rich food like tyramine there will be increased release of monoamines. These excess monoamines cannot be degraded by MAO as it is blocked by MAOI. Thus, this may result in hypeensive crisis. Paresthesia's due to pyridoxine deficiency LIKE IPRONIAZID WEIGHT gain SEXUAL dysfunction Ref. kaplon and sadock, synopsis of psychiatry, 11 th dition, 925", "cop": 1, "opa": "MAOI", "opb": "SSRI", "opc": "NDRI", "opd": "SNRI", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "b68ab6f0-ca94-4f48-94b5-fa8142649f3b", "choice_type": "single"} {"question": "Surgeon excise a poion of liver to the left of the attachment of the falciform ligament. The segments that have been resected are", "exp": "Segmental anatomy of the liver Understanding the internal anatomy of the liver has greatly facilitated safe liver surgery. Couinaud, a French surgeon,described the liver as being divided into eight segments . Each of these segments can be considered as a functional unit, with a branch of the hepatic aery, poal vein and bile duct, and drained by a branch of the hepatic vein. It is the concept of these segments as distinct functional units that guides 'anatomical' liver resection. The overall anatomy of the liver is divided into a functional right and left 'unit'along the line between the gallbladder fossa and the middle hepatic vein (Cantlie's line). Liver segments (V-VIII) to the right of this line are supplied by the right hepatic aery and the right branch of the poal vein, and drain bile the right hepatic duct. To the left of this line (segments I-IV), functionally, is the left liver, which is supplied by the left branch of the hepatic aery and the left poal vein branch, and drains bile the left hepatic duct. Resections can be performed of indi- vidual segments or of the whole of the left or right hemiliver Ref: Bailey and love 27th edition Pg no :1153", "cop": 3, "opa": "Segment 1a and 4", "opb": "Segment 1 and 4b", "opc": "Segment 2 and 3", "opd": "Segment 1 and 3", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d66e6742-e1ec-4c16-a035-acaff02c550a", "choice_type": "single"} {"question": "Most appropriate marker of GIST", "exp": "Refer Robbins page no 789-790 Cd117 is the most impoant diagnostic marker is detectable in 95 percnt of the patients", "cop": 1, "opa": "CD 117", "opb": "CD 34", "opc": "CD 23", "opd": "S-100", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fc93a2a4-6340-4b1f-800e-87fcfd819a13", "choice_type": "single"} {"question": "Anteversion of uterus is maintained by", "exp": "(D) Round ligaments[?]POSITIONS OF UTERUS:Anteversion of uterus: Long axis of uterus is bent forward on long axis of vagina, In most women.Also, long axis of body of uterus is bent forward at level of internal as with long axis of cervix (anteflexion of uterus). Thus, in erect position and with bladder empty, uterus lies in an almost horizontal plane.Fundus and body of uterus are bent backward on vagina so that they lie in rectouterine pouch (pouch of Douglas). Uterus is therefore retroverted. If body of the uterus is, in addition, bent backward on cervix, it is also retroflexed.Angle of Anteflexion is 125degStructures assist in keeping the uterus in position:Sustainer structures: Urogenital diaphragm, Levator ani muscle, Perineal bodySuspensory Structures:Pubocervical ligament, Cardinal ligament (parametrium)Uterosacral ligamentRound ligament of UterusStructures assist in keeping the uterus in Antever- s ion-anteflexion:Cardinal ligament (parametrium):Supports Anteversion, the uterine angle between cervix & body.-Between Vagina & CervixRound Ligament of Uterus:Maintains Anteflexion of the uterus (a position where the fundus of the uterus leans ventrally).-During Pregnancy it gives support to the anteversion as well.Angle of Anteversion 90deg: Maintained by Round & uterosacral ligaments.It has even more significant role during pregnancy. When the uterus grows during pregnancy, the round ligaments can stretch causing pain.#. Position:!. Non pregnant uterus is within the pelvis.!. It is anteverted & anteflexed in position.!. Long axis of cervix is bent on long axis of vagina this is called Anteversion.!. Body of uterus is bent forwards over cervix at the isthmus and is known as Anteflexion.#. Pubocervical ligament:!. Attached Anteriorly to posterior aspect of body of pubis!. Passes to neck of bladder.!. Anterior fornix of vagina.!. Pubocervical ligaments help to maintain normal angle of 45deg between the vagina & horizontal.!. Decrease may cause a cystocoele.", "cop": 4, "opa": "Cardinal ligaments", "opb": "Uterosacral ligaments", "opc": "Pubocervical ligaments", "opd": "Round ligaments", "subject_name": "Anatomy", "topic_name": "Abdomen & Pelvis", "id": "67981693-f8cd-4ef1-88f1-17f2bdb65dbc", "choice_type": "single"} {"question": "A person driving a vehicle is punishable if his alcohol level exceeds", "exp": "In India, as per provisions of section 185 of Motor Vehicles act 1985 whoever while driving or attempting to drive, a motor vehicle, his blood alcohol exceeding 30 mg per 100 ml of blood detected in test by breath analyser shall be punishable with imprisonment of a term which may extend to 6 months or with fine which may extend 2000 rupees or with both. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 191", "cop": 2, "opa": "10mg per 100ml", "opb": "30mg per 100ml", "opc": "50 mg per 100ml", "opd": "80mg per 100ml", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "ad9e4f45-e24e-4166-a6f6-bb3c2f82f236", "choice_type": "single"} {"question": "Aerial supply to the head and neck of femur is", "exp": "The medial circumflex femoral aery (internal circumflex aery, medial femoral circumflex aery) is an aery in the upper thigh that helps supply blood to the neck of the femur. Damage to the aery following a femoral neck fracture may lead to avascular necrosis (ischemic) of the femoral neck/head . Ref - BDC 6th edi vol 2 ; pg 13-15", "cop": 2, "opa": "Lateral circumflex femoral aery", "opb": "Medial circumflex femoral aery", "opc": "Profunda femoris aery", "opd": "External femoral aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "57115bb8-5850-4a9c-b000-91fa80caa816", "choice_type": "single"} {"question": "Sundar Lal 28 year old farmer is found convulsing in the farm. Hea rate is 100/min and blood pressure is 180/110mm Hg. Diarrhoea sweating and urination and Apparent. Pupils are pin point. Drug poisoning is suspected. Most probable cause is", "exp": "Ref-KDT 6/e p104,105 Only symptoms are of antichlorinesterase poisoning accepted raised blood pressure and hea rate. At hugh dose,ACh can stimulates NN and NM receptor. This symptoms may occur due to the nicotinic action of ACh", "cop": 3, "opa": "Acetaminophen overdose", "opb": "Amphetamine toxicity", "opc": "Organo-phosphsphate poisoning", "opd": "Atropine poisoning", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "dfcea880-3085-4d3c-9b94-c7809f9ed6ee", "choice_type": "single"} {"question": "Lockwood ligament is found in", "exp": "A i.e. Orbit - Hammock like check (suppo) ligament k/a suspensory ligament of Lockwood is found in orbit and it retains position of eye & prevent sagging.- Medial orbital wall is formed by body of sphenoid, frontal process of maxilla, lacrimal bone & orbital plate of ethmoidQ. (Mn Buffalo = BFLO).- Inferior orbital fissure lies between lesser wing floor and lateral wall (i.e. b/w maxilla & greater wing of sphenoid). Orbital floor is formed by palatine (orbital process), zygomatic bone & maxillail). Lateral orbital wall is formed by zygomatic (frontal process) & sphenoid (greater wing)Q.", "cop": 1, "opa": "Orbit", "opb": "Pharynx", "opc": "Larynx", "opd": "TMJ", "subject_name": "Anatomy", "topic_name": null, "id": "cd766726-45b5-4bee-b07b-d565a014cb38", "choice_type": "single"} {"question": "Parafolliculars gland of thyroid developed from", "exp": "D. i.e. (Neural crest) (320 - I.B.S 8,h)* Derivatives of Endoderm = Glands(a) Endocrine: Thyroid, Parathyroid, Thymus , Islets of langerhans(b) Exocrine: Liver, Pancreas, Glands in wall of GIT, greater part of prostate (except inner glandular zone) and its female homologous* The superior parathyroid glands arise from caudal pharyngeal complex, the complex probably also gives origin to the parafollicular cells of the thyroid. Which may represent the ultimo branchial body of lower animals.*** \"C- cells\" parafollicuiars, constitute and endocrine system which are derived from neural crest and are found in thyroid, parathyroid and in thymus (544- Rana-shinde 7th)NEURAL -CREST - DERIVATIVES (273-74- IBS 8th)1. The neurons of the spinal posterior nerve root ganglia2. The neurons of the sensory ganglia of the 5, 7, 8, 9 and 10th cranial nerves.3. The Schwann cells that form the neurolemmal sheaths of all peripheral nerves4. The neurons of the sympathetic ganglia5. The specific cells of the adrenal medulla6. Chromaffin tissue7. The pigment cells (melanoblasts**) of the skin8. The pia mater and arachnoidmater are also, probably, derived from the neural crest9. The mesenchyme of the dental papillae (odontoblast**) Some diseases and syndromes are associated with disturbances of the Neural crestHirschsprung's disease (aganglionic megacolon**). Aorticopulmonary septal defects of heart. Cleft lip, cleft palate, frontonasal dysplasia, neurofibromatosis, tumours of adrenal medulla, albinism", "cop": 4, "opa": "Ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Neural crest", "subject_name": "Anatomy", "topic_name": "Embryology", "id": "d65c49bc-ecd0-4a7d-a25c-6aacaefd2221", "choice_type": "single"} {"question": "Eosinophil are activated by", "exp": "ref Robbins 8/e p200; IL 5 is required for the development and maturation of eosinophil Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It is also a key mediator in eosinophil activation.", "cop": 2, "opa": "IL 1", "opb": "IL5", "opc": "IL4", "opd": "IL6", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cd868da0-439b-4a68-8227-fae55cd00756", "choice_type": "single"} {"question": "Short gastric arteries reach the stomach via", "exp": "(B) (Gastrosplenic ligament) (172-snell 7th)* Short gastric arteries- arises from the splenic artery ** at the hilum of the spleen and passes forward in the gastrosplenic omentum (ligament) to supply fundus1. Gastrosplenic ligamentContains short gastric vessels *2. Lino renal ligamentContains splenic vessels and tail of pancreas**3. Phrenico colic ligamentSupports anterior end of spleen and prevent its down ward displacement **** Massive colonic bleeding in a patients with Diverticulosis is from superior Mesentric arterySUPERIOR MESENTERIC SYNDROME (WILKIE'S syndrome!* Caused by compression of the third portion of the duodenum by the superior mesenteric artery, as it passes over this portion of the duodenum* Most commonly seen in young sthenic individuals with woman (w>m)* Predisposing factors- weight loss, supine immobilization scoliosis, placement of body cast (cast syndrome )* Symptoms- Nausea. Vomiting abdominal distension, weight loss , and post prandial epigastric pain* Diagosis-Barium upper GI series, Hypotonic duodenography* Operative treatment of choice for vascular compression of duodenum is - duodeno- jejunostomy", "cop": 2, "opa": "Linorenal ligament", "opb": "Gastrosplenic ligament", "opc": "Gastrophrenic ligament", "opd": "Ligament of treitz", "subject_name": "Anatomy", "topic_name": "Abdomen & Pelvis", "id": "de763b37-6f8e-4037-8165-6e757db3c910", "choice_type": "single"} {"question": "In strasberg classification of bile duct injury, type C is", "exp": "Strasberg classification of Laparoscopic Biliary injuries Type A- Bile leaks from minor ducts still in continuity with the CBD Includes leakage from cystic duct stump and from a subvesical duct of Luschka. MC cause of biliary leaks seen after cholecystectomy. Type B- Occlusion of a pa of the biliary tree, almost always an aberrant right sectoral duct Type C- Transection without ligation of an aberrant right sectoral duct. Type D- A lateral injury to an extrahepatic duct. Type E- Includes biliary strictures, divided into E1 to E5 as classified by Bismuth Ref: Sabiston 20th edition Pgno :1502", "cop": 3, "opa": "Bile leak from a minor duct still in continuity with CBD", "opb": "Injury from bile duct not in communication with CBD", "opc": "Sectoral duct injury with consequent leak", "opd": "Circumferential injury to major bile ducts", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "bf54e80a-9145-4f57-85f9-1ca0b4032b95", "choice_type": "single"} {"question": "Nucleus intercalatus is seen in", "exp": "Nucleus intercalates is present in the medulla at the level of olives between the dorsal nucleus of the vagus nerve (lateral to the intercalated nucleus) and the nucleus of the hypoglossal nerve. Probably involved in the control of the vestibuloocular reflex and may contribute to the veical neural integrator. (Ref: vishram Singh textbook of clinical neuroanatomy second edition pg 77)", "cop": 2, "opa": "Frontal lobe", "opb": "Medulla", "opc": "Temporal lobe", "opd": "Midbrain", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "93c4ee85-2547-4ad8-81e3-fda943343112", "choice_type": "single"} {"question": "Vitamin used for post translational modification of glutamic acid to gamma carboxy glutamate is", "exp": "Ref Robbins 9/e p442 ,119. The vitamin K-dependent carboxylase carries out the posttranslational modification of specific glutamate residues in proteins togamma-carboxy glutamic acid (Gla) in the presence of reduced vitamin K, molecular oxygen, and carbon dioxide.", "cop": 4, "opa": "A", "opb": "D", "opc": "E", "opd": "K", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "844a5a78-7794-4670-a92f-4cd174e9b897", "choice_type": "single"} {"question": "Commonest cause of Cushings syndrome is", "exp": "In most cases, the cause is bilateral adrenal hyperplasia due to hypersecretion of pituitary ACTH or ectopic production of ACTH by a nonpituitary source.", "cop": 4, "opa": "Adrenal adenoma", "opb": "Carcinoma", "opc": "Atrophy", "opd": "Hyperplasia", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "ce5b3105-8ac6-45c4-bbc8-722677df5a18", "choice_type": "single"} {"question": "The tumor suppressor gene p 53 induces cell cycle arrest at", "exp": "Ref Robbins 8/e p290-291 ,9/e p294 The cell cycle has its own internal controls called checkpoint, there are two main checkpoints ,one at the G2/S transition and another at G2/M In the G1/S checkpoint ,cell cycle arrest is mostly mediated through p53, which induces the cell cycle inhibitor p21 Arrest of the cell cycle by the G2/M checkpoint involves both p53 dependant mechanism As can be deduced from above mentioned information that the p53 is associated with both the types of checkpoint , however G2 /M checkpoint can take place even without p53.hence option\" C\" is the preferred anwers", "cop": 3, "opa": "G2_M phase", "opb": "S_G2 phase", "opc": "G2_Sphase", "opd": "G0phase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bae4c7be-d9f8-439a-8d21-c5d03022ce4b", "choice_type": "single"} {"question": "Pudendal canal is a pa of", "exp": "The pudendal canal is an anatomical structure in the pelvis through which the internal pudendal aery, internal pudendal veins, and the pudendal nerve pass. The pudendal canal is a space between obturator fascia and the lunate fascia. Others believe that it is formed by splitting of the obturator fascia ref - BDC 6e vol2 pg362", "cop": 2, "opa": "Colle's fascia", "opb": "Obturator fascia", "opc": "Scarpa's fascia", "opd": "Campors fascia", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "8b9c3ea3-3bea-46df-a5f2-b37941a7c9bd", "choice_type": "single"} {"question": "Flexor digitorum profundus muscle nerve supply is", "exp": "-FDP nerve supply -medial half by ulnar nerve and lateral half by the anterior interosseous nerve- a branch of the median nerve. -reference: Textbook of anatomy ,Upper limb and thorax,Vishram Singh, 2nd edition, page no. 110", "cop": 1, "opa": "Medial half by ulnar nerve", "opb": "Medial half by median nerve", "opc": "Lateral half by ulnar nerve", "opd": "Lateral half byaradial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "4e03bb23-a39a-4466-a696-365b816e95ca", "choice_type": "single"} {"question": "Chronic granulomatous disease is", "exp": "ref Harrison 18/e p 387 It is a congenital and not acquired leucocyte function defect CGD Overview. Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease (PIDD) which increases the body's susceptibility to infections caused by ceain bacteria and fungi. Granulomas are masses of immune cells that form at sites of infection or inflammation.", "cop": 1, "opa": "Associated with formation of multiple granulomas", "opb": "A benign neoplastic process", "opc": "A parasitic disease", "opd": "Acquired leukocyte function defect", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9aef4240-c534-4eb5-b386-66da740c4e07", "choice_type": "single"} {"question": "Preformed antibiodies cause", "exp": "Ref Robbins 9/e p233-234 Hyperacute Rejection Hyperacute rejection occurs within minutes to a few hours after transplantation in a presensitized host and typically is recognized by the surgeon just after the vascular anastomosis is completed. In contrast with a nonrejecting kidney graft, which regains a normal pink color and tissue turgor and promptly excretes urine, a hyperacutely rejecting kidney rapidly becomes cyanotic, mottled, and flaccid and may excrete only a few drops of bloody fluid. The histologic picture is characterized by widespread acute aeritis and aeriolitis, vessel thrombosis, and ischemic necrosis, all resulting from the binding of preformed antibodies to graft endothelium. Viually all aerioles and aeries exhibit char- acteristic acute fibrinoid necrosis of their walls, with narrow- ing or complete occlusion of the lumens by precipitated fibrin and cellular debris", "cop": 1, "opa": "Hyperacute rejection", "opb": "Acute rejection", "opc": "Chronic rejection", "opd": "Acute humoral rejection", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c3393abd-4472-4231-aed9-a608fd1dfa34", "choice_type": "single"} {"question": "Memory T cells can be identified by using the following", "exp": "Ref Harrison 17/e p2021 CD45 (lymphocyte common antigen) is a receptor-linked protein tyrosine phosphatase that is expressed on all leucocytes, and which plays a crucial role in the function of these cells. ... These CD45-associated molecules may play an impoant role in regulatingCD45 tyrosine phosphatase activity and function. Present on memory T cells", "cop": 4, "opa": "CD 45RA", "opb": "CD45RB", "opc": "CD45RC", "opd": "CD45RO", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0e97cd05-876b-4a27-9710-0ae41c0b0ec0", "choice_type": "single"} {"question": "Most effective method of treatment of digitalis toxicity is", "exp": "Refer kDT 7/e p 516 Digoxin toxicity can emerge during long-term therapy as well as after an overdose. It can occur even when the serum digoxin concentration is within the therapeutic range. Toxicity causes anorexia, nausea, vomiting and neurological symptoms. It can also trigger fatal arrhythmias. There is a range of indications for using digoxin-specific antibody fragments. The amount ingested and serum digoxin concentration help to determine the dose required, but are not essential. Digoxin-specific antibody fragments are safe and effective in severe toxicity. Monitoring should continue after treatment because of the small risk of rebound toxicity", "cop": 3, "opa": "Haemodialysis", "opb": "Cardioversion", "opc": "Digoxin antibody", "opd": "Atropine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cd7b6fad-8742-43b4-8c31-b9aaa3ec4e96", "choice_type": "single"} {"question": "Following pattern in DNA electrophoresis is seen in", "exp": ".", "cop": 1, "opa": "Apoptosis", "opb": "Necrosis", "opc": "Dyplasia", "opd": "Metaplasia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "5044b7a0-0fae-41cf-b43b-db46e5d18274", "choice_type": "single"} {"question": "The histological feature of shock includes", "exp": "All the four options is the answer Ref Robbins 7/e p142,9/e p134 Shock is characterized by failure of multiple organ systems.due to systemic hypoperfusioncaused by reduced cardiac output Or ineffective circulatory blood volume The cellular and tissue effects of shock are essentially those of hypoxic injury (Chapter 1) and are caused by a combina- tion of hypoperfusion and microvascular thrombosis. Although any organ can be affected, brain, hea, kidneys, adrenals, and gastrointestinal tract are most commonly involved. Fibrin thrombi can form in any tissue but typically are most readily visualized in kidney glomeruli. Adrenal cor- tical cell lipid depletion is akin to that seen in all forms of stress and reflects increased utilization of stored lipids for steroid synthesis. While the lungs are resistant to hypoxic injury in hypovolemic shock occurring after hemorrhage, sepsis or trauma can precipitate diffuse alveolar damage (Chapter 12), leading to so-called shock lung. Except for neuronal and cardiomyocyte loss, affected tissues can recover completely if the patient survives.", "cop": 1, "opa": "ATN", "opb": "Pulmonary congestion", "opc": "Depletion of lipids in adrenal coex", "opd": "Hepatic necrosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ecf74974-5a79-433c-beba-805d3534db9d", "choice_type": "single"} {"question": "Subcapsular sinuses are seen in", "exp": "Subcapsular sinuses are seen in lymph node INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY SEVENTH EDITION PAGE NO133", "cop": 4, "opa": "Spleen", "opb": "Thymus", "opc": "Thyroid", "opd": "Lymph node", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "3adba6f3-c465-471f-ab84-3195cd95cea9", "choice_type": "single"} {"question": "Most impoant bactericidal agent is", "exp": "H2O2 -MPO - halide system is the most efficient bacterial system of neutrophils It is most efficient in Phagocytosis ref Robb ins 9/e p79", "cop": 4, "opa": "Cationic basic protein", "opb": "Lactoferrin", "opc": "Lysozyme", "opd": "Reactive oxygen species", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "906fb696-5a99-4b94-acba-88b8462f33a6", "choice_type": "single"} {"question": "Deep vein thrombosis is more common after", "exp": "The factors which result in increased risk of venous thrombosis include advancing age and greater complexity of surgical treatment. Ohopedic operations on the lower limbs (hip and knee replacements) are especially likely to result in venous thrombosis.\" - Bailey & Love Ref : Bailey & Love 24/e p969", "cop": 2, "opa": "Prostatic operation", "opb": "Total hip replacement", "opc": "Neurosurgery", "opd": "Gastrectomy", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1f107b8b-0a65-4df8-87aa-7c44e83568a9", "choice_type": "single"} {"question": "The most common cause of pulmonary embolism is", "exp": "About half of the patient with pelvic vein thrombosis or proximal leg deep vein thrombosis have pulmonary thromboembolism. Isolated calf vein thrombosis pose a lower risk of pulmonary embolism. The majority of pulmonary emboli arise from the propagation of lower limb deep vein thrombosis (p. 186). Rare causes include septic emboli (from endocarditis affecting the tricuspid or pulmonary valves), tumour (especially choriocarcinoma), fat following fracture of long bones such as the femur, air, and amniotic fluid, which may enter the mother's circulation following delivery. Ref Davidson edition23rd pg 620", "cop": 3, "opa": "Amniotic fluid embolism", "opb": "Calf vein thrombi", "opc": "Pelvic vein thrombosis", "opd": "Cardio thoracic surgery", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "15407cb0-b648-46f1-b6ea-4e284178a576", "choice_type": "single"} {"question": "Caudate lobe of liver is", "exp": "The caudate lobe of the liver is bounded below, by the poa hepatis; on the right, by the fossa for the inferior vena cava; and, on the left, by the fossa for the ductus venosus and the physiological division of the liver called the ligamentum venosum. It looks backward, being nearly veical in position; it is longer from above downward than from side to side and is somewhat concave in the transverse direction. ref - BDC 6e vol2 pg304-307", "cop": 1, "opa": "I", "opb": "III", "opc": "IV", "opd": "VI", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "09541fa4-ebc5-41e0-b9d2-2dd98cb372e5", "choice_type": "single"} {"question": "Iron deficiency anemia is", "exp": "Cell membrane matyration lags behind the nucleur maturation leading to microcytic appearance", "cop": 3, "opa": "Normochromic normocytic", "opb": "Normocytic hyperchromic", "opc": "Microcytic hypochromic", "opd": "Macrocytic hypochromic", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3dd476f6-6d37-41f4-adde-a4ba9073e8ed", "choice_type": "single"} {"question": "NK cells express", "exp": "Ref Robbins 8/e p188 ;9/e p192 NK cells (belonging to the group of innate lymphoid cells) are defined as large granular lymphocytes (LGL) and constitute the third kind of cells differentiated from the common lymphoid progenitor-generating B and T lymphocytes. NK cells are known to differentiate and mature in the bone marrow, lymph nodes, spleen, tonsils, and thymus, where they then enter into the circulation. NK cells differ from natural killer T cells (NKTs) phenotypically, by origin and by respective effector functions; often, NKT cell activity promotes NK cell activity by secreting interferon gamma. In contrast to NKT cells, NK cells do not express T-cell antigen receptors(TCR) or pan T marker CD3 or surface", "cop": 2, "opa": "CD 15;CD55", "opb": "CD 16; CD 56", "opc": "CD16;CD 57", "opd": "CD21;CD66", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7b0ef95a-e00e-47c6-8d77-53de92f566ac", "choice_type": "single"} {"question": "Most common anatomocal lesion of tongue cancer is", "exp": "Most of 60-70percent of cancer arise from lateral surface of middle third of tongue", "cop": 2, "opa": "Anterior third", "opb": "Lateral margin", "opc": "Dorsum", "opd": "Posterior third", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "17e7a938-5c9e-4230-8d30-1333aba6d7a6", "choice_type": "single"} {"question": "An arrow mark or bird foot mark on the centre of head suggest it is", "exp": "If the head is triangular and covered with small scales, it may be poisonous(viper). If there is an arrow mark or bird foot mark on the centre of the head, it is poisonous (saw scaled viper) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 511", "cop": 2, "opa": "Pit viper", "opb": "Saw scaled viper", "opc": "King cobra", "opd": "Krait", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "70354906-a064-4c6c-8c8f-d409228e683c", "choice_type": "single"} {"question": "Increasing severity of mental retardation in male members over generations is a result of", "exp": "Ref Robbins 8/e p169-171; 9/e p169 Triplet Repeat Mutations: Fragile X Syndrome Fragile X syndrome is the prototype of diseases in which the causative mutation occurs in a long repeating sequence of three nucleotides. Other examples of diseases associated with trinucleotide repeat mutations are Huntington disease and myotonic dystrophy. About 40 diseases are now known to be caused by this type of mutation, and all dis- orders discovered so far are associated with neurodegen- erative changes. In each of these conditions, amplification of specific sets of three nucleotides within the gene disrupts its func- tion. Ceain unique features of trinucleotide repeat muta- tions, described later, are responsible for the atypical pattern of inheritance of the associated diseases. Fragile X syndrome results from a mutation in the FMR1 gene, which maps to Xq27.3. The syndrome gets its name from the karyotypic appearance of the X chromosome inthe original method of diagnosis: Culturing patient cells in a folate-deficient medium typically revealed a discontinuity of staining or constriction in the long arm of the X chromosome. This method has now been supplanted by DNA-based analysis of triplet repeat size as discussed later. With a frequency of 1 in 1550 for affected males and 1 in 8000 for affected females, fragile X syndrome is the second most common genetic cause of mental retardation, after Down syndrome. Clini- cally affected males have moderate to severe mental retar- dation. The characteristic physical phenotype includes a long face with a large mandible, large eveed ears, and large testicles (macroorchidism). Although characteristic of fragile X syndrome, these abnormalities are not always present or may be quite subtle. The only distinctive physi- cal abnormality that can be detected in at least 90% of postpubeal males with fragile X syndrome is macroorchidism. As with all X-linked diseases, fragile X syndrome pre- dominantly affects males. Analysis of several pedigrees, however, reveals some patterns of transmission not typi- cally associated with other X-linked recessive disorders (Fig. 6-17). These include the following: * Carrier males: Approximately 20% of males who, by ped- igree analysis and by molecular tests, are known to carry a fragile X mutation are clinically and cytogeneti- cally normal. Because carrier males transmit the trait through all their daughters (phenotypically normal) to affected grandchildren, they are called normal transmit- ting males.", "cop": 4, "opa": "Mitochondrial DNA mutation", "opb": "Frameshift mutation", "opc": "Y linked disorders", "opd": "Trinucleotide repeat mutation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "18a8247b-9380-445b-b5fb-535fce526890", "choice_type": "single"} {"question": "Drug of choice for mycoplasma pneumonia is", "exp": "Treatment options for acute M.pneumoniae infection include macrolides (e.g., oral azithromycin, 500 mg on day 1, then 250 mg/d on days 2-5), tetracyclines (e.g., oral doxycycline, 100 mg twice daily for 10-14 days), and respira-tory fluoroquinolones Ref Davidson edition23rd pg 585", "cop": 4, "opa": "Penicillin", "opb": "Tetracycline", "opc": "Cefuroxime", "opd": "Erythromycin", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "d07da705-f903-4f1a-8828-f88fae64228a", "choice_type": "single"} {"question": "The subarachnoid space ends at", "exp": "Arachnoid & dural sheath end at the lower end of the S-2 veebra. Subarachnoid space terminates at the caudal (lower border) S-2 veebra. This is also the ending of the sub-dural space. Ref - BDC 6thedition vol 2", "cop": 4, "opa": "L1", "opb": "L2", "opc": "L5", "opd": "S2", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "59721c66-7d12-4dd2-83be-a8fe4138693b", "choice_type": "single"} {"question": "for diagnosisng bulimia nervosa binge eating should be present for a dutration of", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 2, "opa": "once in 3 months", "opb": "once a week", "opc": "once in 2 months", "opd": "once a month", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "8715c495-86ce-4448-af72-4e8a51280382", "choice_type": "single"} {"question": "Chief cells of stomach are most abundant in", "exp": "Cheif cells are present in fundic areas . ref - semantischolar.org", "cop": 1, "opa": "Fundus", "opb": "Body", "opc": "Antrum", "opd": "Pylorus", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9d95bfc7-120a-4707-be06-7bb7e09afe03", "choice_type": "single"} {"question": "Best prognosis after whipple's is seen in", "exp": "Best prognosis : Duodenal adenocarcinoma >Ampullary carcinoma >Distal Bile duct adenocarcinoma >Head of pancreas >Body and tail of pancreas (DAD Head Body and Tail) Ref: Shackelford 7th edition Pgno : 1201", "cop": 2, "opa": "Cholangiocarcinoma", "opb": "CA duodenum", "opc": "CA pancreas", "opd": "Ampullary carcinoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "08abe5a4-3bcb-4aa8-94d1-8b2ece6300a3", "choice_type": "single"} {"question": "Central obesity is seen in;", "exp": "Among given options Central obesity is seen in Cushing's disease. CUSHING'S DISEASE: Form of Cushing's syndrome in which pituitary gland releases too much of ACTH Features of Cushing's syndrome: Moon facies Centripetal Obesity Proximal myopathy Violet/ purple Striae, Thin skin, Purpura Buffalo hump Weight gain / Lemon on sticks description | Peripheral resistance - HTN Insulin resistance - sugar FBS > 126 mg%; 2hr > 200 mg% Coisol | - Activates ENaC - causes salt & water retention; Hypokalemic alkalosis Coisol | - Activates Sex steroid receptors Female - Hirsutism, weight gain, oligomenorrhea, infeility Hyperpigmentation: (+-)", "cop": 1, "opa": "Cushing's disease", "opb": "Chron's disease", "opc": "Conns disease", "opd": "Celiac disease", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "dec9772a-8be7-4999-a123-64f4eb174dcd", "choice_type": "single"} {"question": "Selective beta 2 agonist is", "exp": "Pirbuterol is a beta 2 agonist like salbutamol used for COPD and asthma. Ref: KDT 6th ed pg 129-132", "cop": 2, "opa": "Isoprenaline", "opb": "Pirbuterol", "opc": "Dobutamine", "opd": "Mirabegron", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ec90b579-c3ee-44d4-9ab7-d0a8ea85f814", "choice_type": "single"} {"question": "Best investigation for air in peritoneal cavity is", "exp": "free gas under the diaphragm is best shown on an erect chest x-ray or x ray abdomen. If the patient is too ill for an erect film, a lateral decubitus film is done.", "cop": 3, "opa": "USG", "opb": "CT", "opc": "Xray abdomen erect view", "opd": "Laproscopy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ae466720-fba3-4ad8-8f65-2d3ff4a6e974", "choice_type": "single"} {"question": "Mucinous ascites is seen in", "exp": "Mucinous ascites is seen in pseudomyxoma peritonei colloid ca of stomach or colon with peritoneal implants", "cop": 1, "opa": "Stomach ca", "opb": "Nephrotic syndrome", "opc": "TB", "opd": "Cirrhosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e2b24040-1670-44c1-87a8-4fb186421eea", "choice_type": "single"} {"question": "Feature of shock lung is", "exp": "In ARDS, the presence of alveolar and interstitial fluid and the loss of surfactant can lead to a marked reduction of lung compliance. Without an increase in end-expiratory pressure, significant alveolar collapse can occur at end-expiration,with consequent impairment of oxygenation. Ref Davidson edition23rd pg 199", "cop": 1, "opa": "Diffuse alveolar damage", "opb": "Usual interstitial infiltrates", "opc": "Organizing pneumonia", "opd": "Bronchiolitis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "ff9c8923-b5c9-4441-934d-73ecdaa17b09", "choice_type": "single"} {"question": "Most commonly lesioned nerve in intracranial aneurysms is", "exp": "Intracranial aneurysm may involve oculomotor, abducent and optic nerve in descending order Trochlear nerve is involvement is higher in head trauma. Ref: Gray's 39e/p-227", "cop": 2, "opa": "Optic", "opb": "Oculomotor", "opc": "Trochlear", "opd": "Abducent", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "6bc2c288-82c4-491b-bd3f-60b88e991612", "choice_type": "single"} {"question": "The obstruction of two or more major hepatic veins is seen in", "exp": "Budd-Chiari syndrome It is caused by obstruction of hepatic venous outflow producing intense congestion of the liver Etiology Polycythemia rubra Vera is the most common etiology In the West, thrombosis of the major hepatic veins is more common In BCS all three major hepatic veins usually are occluded Small hepatic veins that join the retro hepatic IVC, paicularly veins draining the caudate lobe are spared Membranous obstruction of IVC is the most common cause of BCS in Japan, China, India and South Africa Infections causing BCS : Filariaisis, amebic liver abscess, aspergillosis, schistosomiasis, syphilitic gumma and hydatid disease Most common cancer associated with BCS : HCC, RCC, adrenal carcinoma and leimyosarcoma of IVC Clinical features Characterized by triad of Ascites+Hepatomegaly+ abdominal pain (Asha) Abdominal pain, abdominal distension, weakness, anorexia and jaundice Signs are massive ascites, hepatomegaly (with hyperophied Caudate lobe), wasting, abdominal venous distension, splenomegaly, jaundice and edema of thighs, legs and feet Jaundice and abdominal venous distension is more common in hepatic vein occlusion Edema of thighs, legs and feet is seen only in IVC occlusion Striking and progressive weakness occur as a manifestation in acute form but not in cirrhotic forms of BCS Ref: Schwaz's principle of surgery 10th edition Pg no : 1283-1284", "cop": 1, "opa": "Budd-Chiari syndrome", "opb": "Reye's syndrome", "opc": "Rotor syndrome", "opd": "Crigler-Najjar syndrome", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0e875125-369d-4715-a798-2b80280533a6", "choice_type": "single"} {"question": "Trachea is lined by", "exp": "Ciliated columnar epithelium is seen in trachea and bronchus Inderbir Singh&;s textbook of human Histology Seventh edition Pg no 45", "cop": 2, "opa": "Simple columnar", "opb": "Pseudostratified columnar", "opc": "Simple cuboidal", "opd": "Stratified squamous, non-keratinized", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "28286b81-310e-495f-97fc-fe9450753bfe", "choice_type": "single"} {"question": "Rider's bone ossify in the", "exp": "In horse riders, the rounded tendon of adductor longus frequently gets calcified as a result of its friction together with the horseback. This calcified tendon is named rider's bone.Reference: Chaurasia Volume II; 7th edition; Page no: 41", "cop": 1, "opa": "Adductor Longus", "opb": "Gluteus Maximus", "opc": "Lateral head of Gastronemius", "opd": "Tibialis Posterior", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e2067527-5f4e-45a5-b304-c7cea872bbb0", "choice_type": "single"} {"question": "The membranous pa of the atrioventricular pa of interventricular septum is between", "exp": "Inderbir Singh&;s Human embryology; Tenth edition; Pg 244The membranous pa of the interventricular septum is divisible into an anterior pa which separates the right and left ventricle and a posterior pa which separates the left ventricle from the right atrium ( also called interventricular septum).", "cop": 2, "opa": "RA & LV", "opb": "LA & RV", "opc": "RA & RV", "opd": "LA & LV", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cf471c4f-9523-4004-887c-c525953103ae", "choice_type": "single"} {"question": "ECT is contraindicated in", "exp": "Raised intracranial pressure is the only absolute contraindication for ECT", "cop": 4, "opa": "Pregnancy", "opb": "Seizure disorder", "opc": "Mania", "opd": "Raised Intracranial pressure", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3495fa94-06e0-4c85-91c6-a383611a4e1e", "choice_type": "single"} {"question": "The function of common neutrophils ,monocytes, macrophages is", "exp": "Ref Robbins 9/e p97 phagocytosis is a major mechanism used to remove pathogens and cell debris. The ingested material is then digested in the phagosome. Bacteria, dead tissue cells, and small mineral paicles are all examples of objects that may be phagocytized. Some protozoa use phagocytosis as means to obtain nutrients The common function of neutrophil ,monocytes and macrophages is phagocytosis it's the most common function", "cop": 2, "opa": "Immune response is reduced", "opb": "Phagocytosis", "opc": "Liberation of histamine", "opd": "Destruction of old erythrocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "63c53c8a-fb0a-4212-9e31-06e974741c7c", "choice_type": "single"} {"question": "The weakness of Vastus Medialis causes", "exp": "The fibers of Vastus medialis are attached medial to cafue half of patella. They prevent lateral displacement of patella.", "cop": 3, "opa": "Patellar Clunk Syndrome", "opb": "Medial dislocation of patella", "opc": "Lateral dislocation of patella", "opd": "Weakness in abduction at Hip joint", "subject_name": "Anatomy", "topic_name": null, "id": "cb0edd8e-068e-4f7e-9061-0ece4efb6912", "choice_type": "single"} {"question": "Common carotid aery divides at the level of", "exp": "At the level of the upper border of the thyroid cailage, the aery ends by dividing into the external and internal carotid aeries. The right common carotid aery is a branch of the brachiocephalic aery. the left common carotid aery is branch of the arch of the aoa. Ref.BDC volume 3 sixth edition pg no: 99", "cop": 3, "opa": "Hyoid bone", "opb": "Cricoid cailage", "opc": "Superior border of thyroid cailage", "opd": "Inferior border of thyroid cailage", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f8e161b5-ebd9-40ef-9ef5-46f1a81b006d", "choice_type": "single"} {"question": "Abdominal pa of esophagus is supplied by", "exp": "AERIAL BLOOD SUPPLY TO ESOPHAGUS: Cervical pa of esophagus Esophageal branches of inferior thyroid aery. Thoracic pa of esophagus PICA (posterior Inter costal aery) (Branch of descending Thoracic aoa) + Bronchial aeries. Abdominal pa of esophagus Left gastric aery (Branch of Celiac trunk) + Inferior phrenic aery (Branch Of abdominal aoa)", "cop": 4, "opa": "Bronchial aery", "opb": "Abdominal aoa", "opc": "Right gastric aery and inferior phrenic aery", "opd": "Left gastric aery and inferior phrenic aery", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "93eda98a-92ba-4049-91a7-50629b492068", "choice_type": "single"} {"question": "The Y chromosome carries a gene on its sho arm that codes for", "exp": "The SRY (sex region Y chromosome) gene present on the sho arm of the Y chromosome codes for TDF (Testes Determining Factor). Presence or absence of this chromosome decides whether the fetus will be male or female. Sex determination is not possible till week 6 i.e. why the embryo is called indeterminate embryo till week 6. External sex differentiation completes after week 11. USG sex determination can be done at this time.", "cop": 3, "opa": "Testosterone", "opb": "MIF", "opc": "Testes-determining factor (TDF)", "opd": "Progesterone", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "720aaff8-2b5e-4911-90c1-4cc354fa42af", "choice_type": "single"} {"question": "Dose limiting toxicity of amphotericin B is", "exp": "Ref-KDT 6/e p759 Amphotericin B can Cause: Dose limiting nephrotoxicity (A) Infusion related reactions (not dose related) Hypokalemia Hypomagnesenia", "cop": 2, "opa": "Infusion related reaction", "opb": "Renal tubular acidosis", "opc": "Myelosuppression", "opd": "Hypotension", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "6b66ea92-4036-4287-84c9-e551c1a6ff2f", "choice_type": "single"} {"question": "NOT a content of carpal tunnel", "exp": "Carpal tunnel Contents - 1. 4 tendons of Flexor Digitorum Profundus (FDP) 2. 4 tendons of Flexor Digitorum Superficialis (FDS) 3. 4 tendons of Flexor Pollicis Longus (FPL) 4. Median nerve Structure passing anterior to carpal tunnel: 1. Ulnar nerve 2. Ulnar aery 3. Palmaris longus tendon. Structure embedded into flexor retinaculum Flexor carpi radialis tendon.", "cop": 3, "opa": "Flexor pollicis longus", "opb": "Flexor digitorum profundus", "opc": "Ulnar nerve", "opd": "Median nerve", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "ce5819fd-1e86-480a-8c90-240395fe21f1", "choice_type": "single"} {"question": "Structure superficial to mylohyoid in anterior digastric triangle is/are", "exp": "Structures passing superficial to mylohyoid: Submandibular gland (superficial pa) Mylohyoid nerve and vessels Submental branch of facial vein & aery Submandibular lymph nodes.", "cop": 4, "opa": "Deep pa of submandibular gland", "opb": "Hypoglossal nerve", "opc": "Pa of parotid gland", "opd": "Mylohyoid aery and nerve", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "c6aaabc1-0b89-45f3-848f-43cb267c2907", "choice_type": "single"} {"question": "The following is not a feature of Alzheimer's disease", "exp": "Reference Robbins page no 1290", "cop": 4, "opa": "Neurofibrillary tangles", "opb": "Senile plaques", "opc": "Amyloid angiopathy", "opd": "Lewy bodies", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6060d207-e2c5-4651-afc7-10cb2a2b592d", "choice_type": "single"} {"question": "Posterior cord of brachial plexus is formed by", "exp": "Cords of brachial plexus are formed by : (i) The lateral cord - It is formed by the union of the ventral divisions of the upper and middle trunks. (ii) The medial cord - It is formed by the ventral division of the lower trunk. (iii) The posterior cord -It is formed by union of the dorsal divisions of all the three trunks. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no., 57.", "cop": 4, "opa": "Ventral division of upper trunk", "opb": "Dorsal division of upper trunk", "opc": "Ventral division of upper, middle and lower trunk", "opd": "Dorsal division of upper, middle and lower trunk", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a50cc6a0-ca6a-4e12-a43a-b458148a7dc7", "choice_type": "single"} {"question": "The drug of choice for chemoprophylaxis for H.influenzae is", "exp": "Oral rifampin is the drug of choice", "cop": 1, "opa": "Rifampin", "opb": "Ceftriaxone", "opc": "Penicillin", "opd": "Erythromycin", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "5536a31a-350a-45c7-bbe3-a255c15bb81a", "choice_type": "single"} {"question": "Follicular carcinoma of thyroid is", "exp": "Follicular cancer of the thyroid 20% of thyroid malignancies More common in iodine-deficient areas Clinical featuresTreatmentPredisposed by long-standing multinodular goiterHematogenous metastasis is more common than lymph nodal metastasis. Pulsatile secondaries may be seen in skull, ribs, pelvis. Malignancy is defined by the presence of capsular and vascular invasion. Hence FNAC cannot differentiate between follicular adenoma and carcinoma Follicular tumors>4 cm size are more likely to be malignant. Follow up can be done using I123 scan or by thyroglobulin estimation. Thyroglobulin levels in patients who have undergone total thyroidectomy should be below 2 ng/ml. Total thyroidectomyProphylactic nodal dissection is not needed because nodal involvement is infrequentIf nodal involvement is seen functional block dissection must be done. If FNAC shows follicular adenoma; lobectomy is enough because 80% of cases are benign. If the biopsy repo becomes positive for malignancy based on angio or capsular invasion. Total thyroidectomy must be done I131 therapyExternal beam RadiotherapyChemotherapy: Adriamycin and taxanes (Refer: Schwaz's Principles of Surgery, 9th edition, pg no: 1363-1365)", "cop": 3, "opa": "The most common thyroid cancer", "opb": "Readily diagnosed thyroid cancer", "opc": "Spreads through hematogenous route", "opd": "Commonly multifocal", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "4f8e58fd-e58f-4752-b25c-4444a9433987", "choice_type": "single"} {"question": "Best site for taking biopsy for viral esophagitis is", "exp": "Refer Robbins page no 768 Herpes virus typically cause punched out ulcers the nuclear inclusions of herpes virus arr found in a narrow rim of degenerating epithelial cells at the margin of ulcer For biopsy should be taken from edge of ulcer in HSV and base of ulcer in CMV", "cop": 2, "opa": "Edge of ulcer", "opb": "Base of ulcer", "opc": "Adjacent induratrd area around ulcer", "opd": "Surrounding normal mucosa", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ad8b5a18-f5a6-4d1e-8775-c1f868605148", "choice_type": "single"} {"question": "Not an inverter of foot is", "exp": "Inverters of foot are\n\nTibialis anterior\nTibialis posterior\nFlexor digitorum longus", "cop": 2, "opa": "Flexor digitorum longus", "opb": "Peroneus tertius", "opc": "Tibialis posterior", "opd": "Tibialis anterior", "subject_name": "Anatomy", "topic_name": null, "id": "00b72e7e-42c8-455a-be4c-4ad0ad9f91a7", "choice_type": "single"} {"question": "Nerve involved in Guyon&;s canal syndrome is", "exp": "Guyon&;s canal is formed by the pisiform and hamate and the ligament that connects them. The ulnar nerve and ulnar aery run through the tunnelGuyon&;s canal syndrome is also known as handlebar palsy (seen in cyclists)", "cop": 3, "opa": "Axillary nerve", "opb": "Median nerve", "opc": "Ulnar nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "077ed7ec-4e61-491e-aff6-7c9a20331522", "choice_type": "single"} {"question": "Somatic efferent does not include", "exp": "Somatic efferent nerves, also called as general somatic efferent (GSE) nerves, supply skeletal muscle of somatic origin ( muscles of eye and tongue).\nSomatic efferent nerves include,\n\nOculomotor nerve - 3rd nerve\nTrochlear nerve - 4th nerve\nAbducent nerve - 6th nerve\nHypoglossal nerve - 12th nerve", "cop": 1, "opa": "Facial nerve", "opb": "Oculomotor nerve", "opc": "Abducent nerve", "opd": "Trochlear nerve", "subject_name": "Anatomy", "topic_name": null, "id": "54d7b858-9eee-4db9-8fce-ba9956a55fc9", "choice_type": "single"} {"question": "Middle meningeal aery is a branch of", "exp": "First pa of maxillary aery 1.deep auricular 2.anterior tympanic 3.middle meningeal 4. Accessory meningeal 5.inferior alveolar Second pa of maxillary aery 1.masseteric 2.deep temporal 3.pterygoid 4.buccal Third pa of maxillary aery 1.posterior superior alveolar 2.infraorbital 3.greater palatine 4.pharyngeal 5. Aery of pterygoid canal 6.spenopalatine Ref BDC volume 3;sixth edition pg 119", "cop": 1, "opa": "1st pa of maxillary aery", "opb": "2nd pa of maxillary aery", "opc": "3rd pa of maxillary aery", "opd": "External pa carotid aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d6954d46-e0eb-4880-9808-adeb6617d645", "choice_type": "single"} {"question": "Interosseous recurrent aery is a branch of", "exp": "Posterior interosseous aery originates from common interosseous branch of ulnar aery. It gives a branch - recurrent interosseous aery to the vascular network around the elbow joint. Ref : Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 778.", "cop": 2, "opa": "Anterior interosseous aery", "opb": "Posterior interosseous aery", "opc": "Common interosseous aery", "opd": "Radial aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "d687b9a2-ff28-426e-8c5d-5608ed99a8b9", "choice_type": "single"} {"question": "The best prognosis is gastric carcinoma is in type", "exp": "Reference p772-773 The Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. Early symptoms may include heaburn, upper abdominal pain, nausea and loss of appetite. Later signs and symptoms may include weight loss, yellowing of the skin and whites of the eyes, vomiting, difficulty swallowing and blood in the stool among others Prognosis Five-year survival rate < 10% (globally),28% (US), 65% (S. Korea", "cop": 4, "opa": "Linitis plastic", "opb": "Polypoidal growth", "opc": "Ulcerative", "opd": "Superficial spreading", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "71b47bfb-8f2c-48c4-b384-bfe2f9cd2452", "choice_type": "single"} {"question": "The left recurrent laryngeal nerve recurs around the", "exp": "Early in embryological development, both the right and left recurrent laryngeal nerves hook (recur) around aoic arch 6. The left aoic arch 6 persists as the ductus aeriosus(distal pa) while proximal pa of it forms pulmonary aery. 6TH phyrangeal arch derivatives:- Nerve-reccurent laryngeal nerve Aery- pulmonary aery (and ductus aeriosus) Muscles - all muscles of larynx except cricothyroid.", "cop": 4, "opa": "Left primary bronchus", "opb": "left subclan aery", "opc": "Left subclan vein", "opd": "Ductus aeriosus", "subject_name": "Anatomy", "topic_name": "CVS Embryology", "id": "e21657cb-ccb2-4071-9252-893ddd6c8c30", "choice_type": "single"} {"question": "Hyperglycemia Associated with", "exp": "The clinical manifestations resulting from the production of metabolic active substance by neoplastic tissue,have been labelled paraneoplastic syndrome.adolescent patients with osteosarcoma Demonstrate abnormal growth hormone ,insulin,growth hormone response to oral glucose loading in78% of the study population No statistical association exists between any of the two or three factors There fore no primary abnormality can be identified high somatomedin levels were noted 72%of group study accompanied by Simultaneous elevation of Growth hormone Study adrenal ,gonadal, gonadotropic hormone were essentially normal thrreby ruling these out as endocrine abnormalities Hyperglycemia is also aAssociated with condrosarcoma and fibrosarcoma", "cop": 3, "opa": "Multiple myeloma", "opb": "Ewing's sarcoma", "opc": "Osteosarcoma", "opd": "Chondroblastoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1b2940b3-8678-4e4a-861b-f13b3e6ec6d8", "choice_type": "single"} {"question": "A man was brought to the emergency after meeting with an accident and injured his perineum He gets our urge to micturate but its yuable to pass urine Ole blood was Sti at the tip of urethra and swelling of penis and scrotum", "exp": "REF : BD CHAURASIA", "cop": 2, "opa": "Penile urethra rupture", "opb": "Bulbar urethra", "opc": "Membraneous urethra", "opd": "Urinary bladder injury", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "bc5c9d24-55b5-4505-8b94-9d64990ff6b8", "choice_type": "single"} {"question": "Hyper viscosity is seen in", "exp": "Ref William hematology 6/e p1268 The term cryoglobulinemia refers to the presence in the serum of proteins that precipitate at temperatures below 37 degrees C and redissolve on rewarming. ... The elective treatment for hyperviscosity syndrome, whether associated with monoclonal, mixed, or polyclonalcryoglobulinemia, is plasma exchange.", "cop": 1, "opa": "Cryoglobulinemia", "opb": "Multiple myeloma", "opc": "MGUS", "opd": "Lymphoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f79a972f-3611-4cdc-837e-ce2f9393f592", "choice_type": "single"} {"question": "Hyoid bone is closely associated with", "exp": "Hyoid bone is closely associated with the thyroglossal tract from which thyroglossal cyst & fistula originate, thus during surgical excision of the thyroglossal cyst or fistula, the central pa of the hyoid bone is excised (otherwise recurrence may occur). Ref : Bailey Love 25/e p730", "cop": 2, "opa": "Ludwig's angina", "opb": "Thyroglossal cyst", "opc": "Branchial cyst", "opd": "Cystic hygroma", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "72223ccd-104a-481a-b32a-9ff2e27895ea", "choice_type": "single"} {"question": "Causes for reduced bioavailability include", "exp": "Ref-KDT 7/e p18 the causes of low availability are reduced absorption highfirst pass metabolism", "cop": 1, "opa": "high first pass metabolism", "opb": "increased absorption", "opc": "high lipid solubility", "opd": "non ionization", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "975b08f4-61fe-430a-a5c0-cef2b958f44a", "choice_type": "single"} {"question": "A 88year old male patient presented with endstage renal disease with coronary Aery block and metastasis in the lungs. Now presents with acute cholecystitis, patients relatives need treatment to do some thing", "exp": "Tube cholecystectomy If patients are unfit for surgery, per cutaneous, ultrasound guided or CT guided cholecystectomy is the treatment of choice Ref: Sabiston 20th edition Pgno :1496", "cop": 2, "opa": "Open cholecystectomy", "opb": "Tube cholecystectomy", "opc": "Laparoscopic cholecystectomy", "opd": "Antibiotics then elective cholecystectomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f10fab92-6942-4309-a24b-238167836626", "choice_type": "single"} {"question": "Tonsil is formed from", "exp": "Second Pouch(a) The epithelium of the ventral pa of this pouch contributes to the formation of the tonsil.(b) The dorsal pa takes pa in the formation of the tubotympanic recess.Reference: Inderbir Singh Embryology; 10th edition; Page no: 135", "cop": 2, "opa": "Ist Pharyngeal pouch", "opb": "IInd Pharyngeal pouch", "opc": "IIIrd Pharyngeal pouch", "opd": "IV Pharyngeal pouch", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1b21f110-827b-419f-ba2b-990b7e610252", "choice_type": "single"} {"question": "Length of adult trachea", "exp": "Trachea is 10-15 cm length. BD CHAURASIA'S HUMAN ANATOMY VOLUE1 .6 TH EDITION. PAGE NO 281", "cop": 2, "opa": "5-6 cm", "opb": "10-11 cm", "opc": "15-16cm", "opd": "20-21cm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "bc59a038-6b4e-468d-813f-8f14afa39003", "choice_type": "single"} {"question": "The posterior 1/3 of the tongue is supplied by....nerve", "exp": "D i.e. Glossopharyngeal", "cop": 4, "opa": "Hypoglossal", "opb": "Chorda tymapni", "opc": "Lingual", "opd": "Glossopharyngeal", "subject_name": "Anatomy", "topic_name": null, "id": "10749e64-920e-4ced-84a5-8631a007cd47", "choice_type": "single"} {"question": "Appropriate treatment for the mild congenital ptosis;", "exp": "Treatment of Congenital ptosis In severe ptosis, surgery should be performed at the earliest to prevent stimulus deprivation amblyopia. In mild and moderate ptosis, surgery should be delayed until the age of 34 years, when accurate measurements are possible. - Congenital ptosis can be treated by any of the following operations: Tarso-conjunctivo - Mullerectomy (Fasanella-Servat operation). It is performed in cases having mild ptosis (1.5-2 mm) and good levator function. In it, upper lid is eveed and the upper tarsal border along with its attached Muller's muscle and conjunctiva are resected. Levator resection. It is a very commonly performed operation for moderate and severe grades of ptosis It is contraindicated in patients having severe ptosis with poor levator function. Techniques: Levator muscle may be resected by either conjunctival or skin approach. Conjunctival approach (Blaskovics' operation) Skin approach (Eversbusch's operation) 3. Frontalis sling operation (Brow suspension). This is performed in patients having severe ptosis with no levator function.", "cop": 1, "opa": "LPS Resection", "opb": "Antibiotics and hot compression", "opc": "Tarsal fracture", "opd": "Wedge resection of conjunctiva", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "1516ef77-95fc-43c3-aeb4-d557c7693105", "choice_type": "single"} {"question": "Opening of jaw is done by", "exp": "Lateral pterygoid is sho, conical, and has upper and lower heads. The lateral pterygoid: - depress mandible to open mouth, with suprahyoid muscles. - protrudes mandible - right lateral pterygoid turns the chin to left side.", "cop": 2, "opa": "Temporalis", "opb": "Lateral pterygoid", "opc": "Med pterygoid", "opd": "Masseter", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "db9483df-c6b3-4357-a955-196f122ac5d5", "choice_type": "single"} {"question": "The cailage of A is", "exp": "The epiglottis is a leaf-shaped elastic cailage situated behind the root of the tongue.", "cop": 2, "opa": "Fibrous", "opb": "Elastic", "opc": "White fibro-cailage", "opd": "Hyaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3b3567b9-8fa8-4a86-9c58-aa8b898058ac", "choice_type": "single"} {"question": "Lacrimal punctum of upper and lower eyelid is", "exp": "Each lacrimal canaliculus begins at the lacrimal punctum and is 10 mm long.it has a veical pa which is 2mm long and a horizontal pa which is 8 mm long. There is a dilated ampulla at the bend,both canaliculi open close to the each other in the lateral wall of the lacrimal sac behind the medial palpebral ligament. ref.BDC volume 3;sixth edition pg 76", "cop": 1, "opa": "They are opposed", "opb": "No relation", "opc": "Upper punctum is medial", "opd": "Upper punctum is lateral", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "aa9e36bc-e633-4cd6-af28-880020cf93be", "choice_type": "single"} {"question": "The interossei are supplied by", "exp": "Deep palmar arch is formed mainly by terminal pa of the radial aery and is completed medially at the base of fifth metacarpal bone by the deep palmar branch of the ulnar aery. Superficial palmar branch of radial aery joins with the ulnar aery laterally to form a superficial palmar arch which supplies the digits. Deep palmar branch of ulnar aery joins with the radial aery to form deep palmar arch and supplies interossei muscles. BD Chaurasia 7th edition Page no: 126,127", "cop": 4, "opa": "Superficial palmar branch of radial aery", "opb": "Deep palmar branch of ulnar aery", "opc": "Superficial palmar arch", "opd": "Deep palmar arch", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "1e4349fb-dd2e-4835-ae0c-7ff24985736a", "choice_type": "single"} {"question": "Predominant blood supply to the supraduodenal bile duct is derived from", "exp": "Blood supply of supraduodenal bile duct Axial Blood supply: (98%) The most impoant of these vessels run along the lateral borders of the bile duct and are called the &;3 o clock &; and &;9 o clock&; aeries. 60% of the blood supply occurs from the duodenal (caudal) end of the duct primarily from branches of the retroduodenal aery (posterior superior pancreaticoduodenal aery). 38% of the blood supply occurs from the hepatic (cephalic) end of the right hepatic aery. Non-axial blood supply: only 2% of blood supply to the supraduodenal bile duct from the branches of the hepatic aery proper. Ref: Gray&;s Anatomy 41st edition Pgno: 1176", "cop": 1, "opa": "Vessels that run upward along the bile duct from the duodenal end of the duct such as the retroduodenal and the gastroduodenal aeries retro", "opb": "Vessels that run downward along the bile duct from the hepatic and of the duct as the right hepatic aery", "opc": "Vessels that arise from the hepatic aery proper as it runs up along the common bile duct and supplies it with twigs in a non-axial distribution", "opd": "Vessels that arise from the cystic aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "2f6d9d21-c263-4546-a762-9b023157c678", "choice_type": "single"} {"question": "The structure not passing through the aoic opening of the diaphragm is", "exp": "The vagal trunk does not pass through the aoic opening of the diaphragm. It passes through the esophageal opening at the level of T10 veebrae. Major openings through the diaphragm Level of opening T8 T10 T12 Located in In the central tendon In the muscular pa In the crus of the diaphragm Structures passing through Inferior venacava Right Phrenic nerve Oesophagus Vagus nerve-right and left Aoa Thoracic duct Azygous vein Hemiazygous vein Ref: Gray's Anatomy 41st edition Pgno: 899", "cop": 4, "opa": "Aoa", "opb": "Azygous vein", "opc": "Thoracic duct", "opd": "Vagal trunk", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2763442a-549e-4778-8fcb-a02dab07fcbe", "choice_type": "single"} {"question": "Iliofemoral ligament arise from", "exp": "ILIOFEMORAL LIGAMENT:- Inveed Y shaped ligament of Bigelow.Lies anteriorly One of the strongest ligament.Triangular in shape. Attachments:-Apex: lower half of anterior inferior iliac spine. Base: interochanteric line. Action: prevent trunk from falling backwards in standing posture. Fibres:-Upper oblique and Lower veical fibres form thick and strong bands.Middle fibres: thin and weak. {Reference: BDC 6E pg no.137}", "cop": 4, "opa": "Ischial tuberosity", "opb": "Anterior superior iliac spine", "opc": "Iliopubic rami", "opd": "Anterior inferior iliac spine", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7fdef0d7-8c46-4785-b938-5ce25cc950e1", "choice_type": "single"} {"question": "Trendelenburg test is positive on right side. Nerve injured is", "exp": "Superior gluteal nerve, if injured, paralyses the 3 muscles: gluteus medius, gluteus minimus and tensor fascia latae and hence lead to Trendelenberg test positive, which is evident on the contralateral side. Pelvis sags on the unsuppoed lower limb. In Trendelenberg test the action of gluteus medius (superior pelvic tilt of contralateral hip) is absent and we actually observe that there is a downward drop of the unsuppoed hip -due to unopposed action of gravity. This leads to Lurching gait in the patient.", "cop": 4, "opa": "Right Inferior gluteal", "opb": "Right Femoral", "opc": "Right Superior gluteal", "opd": "Left Superior gluteal", "subject_name": "Anatomy", "topic_name": "Nerve supply of Lower Limb", "id": "b691f8b2-fed7-4b2c-b06c-ea5d36138c5d", "choice_type": "single"} {"question": "Brunner's gland is a histological finding of", "exp": "Brunner's gland is a histological finding of duodenum which is present in submucosa which secretes mucus which is alkaline in nature and neutralises the acid in duodenum so that enzymes could work at their optimum pH.It also heals the ulcer by increasing mitotic activity. Peyer patches or Lymphoid follicles seen in Lamina propria.", "cop": 3, "opa": "Esophagus", "opb": "Stomach", "opc": "Duodenum", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "Small and Large intestine", "id": "b9500b51-4c5d-4c5f-a818-99d0f6ae5740", "choice_type": "single"} {"question": "Branch of pharmacology that deals with medicinal drugs that are obtained from plants and other natural resources are known as", "exp": "Ref-K.K.Sharma 2nd/4 Defination", "cop": 1, "opa": "Pharmacognosy", "opb": "Pharmacogenetics", "opc": "Pharmacogenomics", "opd": "Pharmacopoeia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "74c807d0-6e1d-434d-ba12-a89086ce2c1b", "choice_type": "single"} {"question": "Defective fumarylacetoacetate hydrolase enzyme is associated with", "exp": "Defective fumarylacetoacetate hydrolase enzyme is associated with type I tyrosinemia (tyrosinosis). it is the most common type of tyrosinemia. Therapy employs a diet low in tyrosine and phenylalanine and nitisinone (NTBC). Reference: Harpers illustrated biochemistry 30th edition", "cop": 1, "opa": "Type 1 Tyrosinemia", "opb": "Type 2 Tyrosinemia", "opc": "Type 3 Tyrosinemia", "opd": "Type 4 Tyrosinemia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "518a7590-0c51-40b1-988a-05b6a78633b1", "choice_type": "single"} {"question": "Dorsiflexion of ankle joint is by", "exp": "Muscles producing movements of ankle - A. Dorsiflexion : Tibialis anterior is the principal muscle,(Extensor digitorum anterior longus, Extensor hallucis longus,Peroneus teius are the accessory muscles) B. Plantar flexion : Gastrocnemius and Soleus are the principal muscles ( plantaris, Tibialis posterior, Flexor hallucis longus, Flexor digitorum longus are the accessory muscles) Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2 , pg. no. 161 ( table 12.3 )", "cop": 1, "opa": "Tibialis anterior", "opb": "Peroneus longus", "opc": "Tibialis posterior", "opd": "Soleus", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "fafb802d-fa37-4bca-8e23-ee8a87e87df4", "choice_type": "single"} {"question": "The upper half of the esophagus in lined by", "exp": "INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:263 The mucosa The mucous membrane of the oesophagus shows several longitudinal folds that disappears when the tube is distended The mucosa is lined by stratified squamous epithelium which is normally not keratinized", "cop": 3, "opa": "Stratified cuboidal epithelium", "opb": "Stratififed squamous epithelium", "opc": "Stratififed squamous non keratinsed epithelium", "opd": "Stratififed squamous keratinised epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "29e6751c-43ef-477e-8c86-3b3c81fe82ac", "choice_type": "single"} {"question": "The nerve piercing sphenomandibular ligament is", "exp": "Nerve to mylohyoid pierces sphenomandibular ligament.", "cop": 3, "opa": "Superior alveolar nerve", "opb": "Inferior alveolar nerve", "opc": "Nerve to mylohyoid", "opd": "Lingual nerve", "subject_name": "Anatomy", "topic_name": null, "id": "b19b4de0-eeb0-4893-9577-4bbd194ac887", "choice_type": "single"} {"question": "Bones ossified at bih", "exp": "Secondary centers around knee joint ( distal femur and proximal tibia) appear during last weeks of intrauterine life (or immediately after bih) Primary center of all tarsal bones (except talus, calcaneus and cuboid) appear after bih Ref: Gray's39e/p185-210", "cop": 3, "opa": "Upper end of humerus", "opb": "Lower end of humerus", "opc": "Lower end of femur", "opd": "Lower end of tibia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c1c943bf-e59a-455e-b41d-216089d44f8a", "choice_type": "single"} {"question": "Components of acellular peussis vaccine", "exp": "aP Avoids neuro side effects of whole cell peussis but less immunogenic", "cop": 1, "opa": "PT + FHA + Fimbriae", "opb": "PT + cytotoxin + fimbriae", "opc": "Endotoxin + fimbriae + pili", "opd": "Peactin + FHA + OMP + Fimbriae", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "40f21410-877c-4dd7-9c39-88185a967d7c", "choice_type": "single"} {"question": "Hatter's shake or glass blower's shake seen in", "exp": "Mercurial Tremors The hands are first affected. there will be tremors of the hands called Danbury tremors. It may progress to lips, tongue, arms, and legs. The tremors are moderately coarse and intentional to sta with and are interspersed by jerky movements. The advanced condition is called hatter's shake or glass blower's shake. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 428", "cop": 2, "opa": "Arsenic poisoning", "opb": "Mercury poisoning", "opc": "Lead poisoning", "opd": "Copper poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "a1d9f303-5020-4b6d-ac7c-706baff3b1f3", "choice_type": "single"} {"question": "Coronary vein is", "exp": ".", "cop": 1, "opa": "Left Gastric vein", "opb": "Right Gastric vein", "opc": "Left Gastroepiploic vein", "opd": "Right Gastroepiploic vein", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "59839f13-71b0-455c-b88d-76deaa5e29bc", "choice_type": "single"} {"question": "Root value of medial cutaneous nerve of thigh", "exp": "The medial cutaneous nerve of the thigh (L2, L3) - It is a branch of the anterior division of the femoral nerve. It divides into anterior and posterior divisions. The nerve supplies the skin on the medial side of the lower two thirds of the thigh, and of the upper one-third of the leg. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2, pg. no., 45.", "cop": 2, "opa": "L1L2", "opb": "L2L3", "opc": "L4L5", "opd": "L5S1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "441043bc-0692-4415-bf91-9c920b1d3cd6", "choice_type": "single"} {"question": "Most radiosensitive tumor is", "exp": "Ref Robbins 8/e p989 In general, radiation therapy is mainly used for patients with seminoma, which is very sensitive to radiation. Sometimes it's used after orchiectomy (the operation to remove the testicle) and is directed at the lymph nodes at the back of the abdomen (the retroperitoneal lymph nodes). This is to kill any tiny bits of cancer in those lymph nodes that can't be seen. It can also be used to treat small amounts of seminoma that have spread to the nodes (based on changes seen on CT and PET scans).", "cop": 4, "opa": "Renal cell carcinoma", "opb": "Carcinoma colon", "opc": "Hepatocellular carcinoma", "opd": "Testicular seminoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ad1bf295-f926-45dd-a8c5-f3f4dcb8f6b7", "choice_type": "single"} {"question": "Characterisic microscopic features of Osteogenic sarcoma is", "exp": "Osteoid formation by Mesenchymal cells with large Pleomorphism Ref :Robbins 8th/1226", "cop": 2, "opa": "Osteoid formation", "opb": "Osteoid formation by Mesenchymal cells with pleomorphism", "opc": "Codmans triangle", "opd": "Predominant osteoclast", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "6ad35d08-d496-4fe2-844a-d34385557566", "choice_type": "single"} {"question": "Collecting tubules of human kidney originate from", "exp": "C. i.e. Ureteric bud", "cop": 3, "opa": "Mesonephros", "opb": "Metanephros", "opc": "Ureteric", "opd": "Mesonephric duct", "subject_name": "Anatomy", "topic_name": null, "id": "a66379f1-da01-474f-ab37-e29d65dd7d50", "choice_type": "single"} {"question": "Zafirlukast used in asthmatic patients acts by", "exp": "Drugs for Bronchial AsthmaMechanism of actionDrugsBronchodilators b2 sympathomimetics Salbutamol, Terbutaline, Bambuterol, Salmeterol, Formoterol, Ephedrine Methylxanthine Theophylline, Aminophylline, Choline theophyllineAnticholinergics Ipratropium bromide, Tiotropium bromide Leukotriene antagonist Montelukast, Zafirlukast Mast cell stabilizers Sodium cromoglycate, Ketotifen Coicosteroids Systemic Hydrocoisone, Prednisolone Inhalational Beclomethasone, Budesonide, Fluticasone, Flunisolide, Ciclesonide Anti IgE antibody Omalizumab (Refer: Rang and Dale's Clinical Pharmacology, 7th edition, pg no: 345)", "cop": 3, "opa": "Phosphodiesterase inhibition", "opb": "Endothelium receptor blockage", "opc": "Leukotriene receptor blockage", "opd": "Lipoxygenase inhibitor", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "af78d7d3-cb7a-4c9e-ad22-cfe40be06df8", "choice_type": "single"} {"question": "Dose of radiation per study in mammography is", "exp": ".", "cop": 1, "opa": "0.1cGy", "opb": "0.2", "opc": "0.3", "opd": "0.4", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "05cb4f10-f1e2-40c2-9d2f-6e4d99dfb847", "choice_type": "single"} {"question": "The roots and trunks enter the posterior triangle of the neck by passing", "exp": "The roots and trunks enter the posterior triangle of the neck by passing between the anterior scalene and middle scalene and lie posterior & superior to subclavian Artery.", "cop": 1, "opa": "Between the anterior scalene and middle scalene muscles", "opb": "Between the middle scalene and posterior scalene muscles", "opc": "Behind subclavius muscle", "opd": "Posterior and inferior subclavian Artery", "subject_name": "Anatomy", "topic_name": null, "id": "54e057ce-849c-4f27-95f6-e0fbfc68522e", "choice_type": "single"} {"question": "A 35 year old athlete has height 184 cm , arm span 194 cm, pulse rate 64/min , BP 148/64 mm Hg . Chest auscultation reveals long Diastolic murmur over right 2nd intercostal space on routine examination. The probable diagnosis is", "exp": "Ref Harrison 19 th ed pg 1536 Arm span greater than height is suggestive of MarfansM syndrome. Aoic regurgitation is a feature associated with Marfan's as well as consistent with a diastolic murmur is second right intercostal space.", "cop": 1, "opa": "Aoic regurgitation", "opb": "Atrial septal defect", "opc": "Ebstein anomaly", "opd": "Coarctation of aoa", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5a68d686-c48d-432a-ba78-cd84a4846ddb", "choice_type": "single"} {"question": "VIII cranial nerve affects", "exp": "The vestibulocochlear nerve consists of two divisions: cochlear and vestibular.Cochlear nerve innervate the organ of Coi and is associated with hearingVestibular nerve innervates the vestibular receptors in the semicircular ducts(kinetic balance) and in the utricle and saccule(for static balance) in the ear.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg- 103)", "cop": 2, "opa": "Taste", "opb": "Equilibrium", "opc": "Touch", "opd": "Smell", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "33335c03-729f-4a3d-a611-18b40b0af12c", "choice_type": "single"} {"question": "Dorello canal transmitts", "exp": "Dorello's Canal is the bow-shaped bony enclosure surrounding the abducens nerve and the inferior petrosal sinus as the two structures merge with the cavernous sinus. This canal is named after the famous Italian anatomist Primo Dorello, who proved the existence of this canal after a series of meticulous dissections . Ref - pubmed.com", "cop": 4, "opa": "Middle meningeal aery", "opb": "Mandibular nerve", "opc": "Superior alveolar branch of maxillary nerve", "opd": "Abducent nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "5ef3d300-c8b4-4269-9c38-afb272692503", "choice_type": "single"} {"question": "Action of Lumbricals is", "exp": "Action of Lumbricals is Flexion at Metacarpo - phalangeal joint and extension at Interphalangeal joint.", "cop": 3, "opa": "Flexion at Metacarpo - Phalangeal joint and flexion at Interphalangeal joint", "opb": "Extension at Metacarpo - Phalangeal joint and extension at Interphalangeal joint", "opc": "Flexion at Metacarpo - Phalangeal joint and extension at Interphalangeal joint", "opd": "Extension at Metacarpo - Phalangeal joint and flexion at Interphalangeal joint", "subject_name": "Anatomy", "topic_name": null, "id": "e3a3c296-db28-42f7-a366-7f89dc6bebfd", "choice_type": "single"} {"question": "I time required to reach the steady state after a dosage regimen depends on", "exp": "after a dosage regimen, concentraton of the drug to reach the stead state (when the eliminaton balances the input) is called steady state plasma concentration cpss cpss is reached in about 4-5 half lives. the amplitule fluctuations in Cpss depends on the dose interal relative t1/2 Ref-KDT 6/e p32", "cop": 2, "opa": "Route of Administration", "opb": "Half life of drug", "opc": "Dose interval", "opd": "Dosage of the drug", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0c1b75b8-8b8d-4df1-8b17-a169e06a1c49", "choice_type": "single"} {"question": "Structure derived from first pharyngeal arch", "exp": "Ref:- Keith L. Moore -The Developing Human 9th Edition; Pg num:- 165", "cop": 1, "opa": "Anterior belly of digastric", "opb": "Stylohyoid", "opc": "Levator veli palatini", "opd": "Buccinator", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9df840a9-bb7d-4810-8f67-e1d1e39daafd", "choice_type": "single"} {"question": "Ground glass appearance is seen in", "exp": "Refer Robbins page no 1231 8th edition The lesions of fibrous dysplasia are well circumscribed, intra- medullary, and vary greatly in size. Larger lesions expand and disto the bone. The lesional tissue is tan-white and gritty and is composed of curvilinear trabeculae of woven bone sur- rounded by a moderately cellular fibroblastic proliferation. The curvilinear shapes of the trabeculae mimic Chinese characters, and the bone lacks prominent osteoblastic rimming (Fig. 26-38). Nodules of hyaline cailage with the appearance of disorga- nized growth plate are also present in approximately 20% of cases. Cystic degeneration, hemorrhage, and foamy macro- phages are other common findings.", "cop": 3, "opa": "Inveed pappilomma", "opb": "Fibro calcification", "opc": "Fibrous dysplasia of bone", "opd": "Chronic osteomyelitis", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "1f212664-10ae-432c-92ac-887f5e44d5de", "choice_type": "single"} {"question": "Haemolytic disease of newborn is an example of", "exp": "Ref Robbins 7/e p211,9/e p206 Autoimmune hemolytic Anemia Red cell membrane proteins (Rh blood group antigens, I antigen) Opsonization and phagocytosis of erythrocytes Hemolysis, anemia Autoimmune thrombocytopenic purpura thrombocytopenic Platelet membrane proteins (GpIIb/IIIa integrin) Opsonization and phagocytosis of platelets..leads to bleeding..type 2 hypersensitivity reaction", "cop": 2, "opa": "Type 3 hypersensitivity reaction", "opb": "Type2 hypersensitivity reaction", "opc": "Ahur reaction", "opd": "Type 4 hypersensitivity reactions", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "97e5b4e5-9a1d-4064-bb9b-c9d324a3ac08", "choice_type": "single"} {"question": "Fibromuscular stroma is present in", "exp": "Fibromuscular stroma occupies the anterior surface of the prostate gland anterior to the urethra and is composed of dense irregular connective tissue with a large number of smooth muscle fibersReference: Chaurasia; 6th edition", "cop": 3, "opa": "Testis", "opb": "Liver", "opc": "Prostate", "opd": "Urinary bladder", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94135cff-a1da-46c2-9c25-fb1c81363480", "choice_type": "single"} {"question": "Most sensitive and specific test for diagnosis of iron deficiency is", "exp": "Ref Harrison 19 th ed pg 627,628 Under steady-state conditions, the serum ferritin level correlates with total body iron stores; thus, the serum ferritin level is the most convenient laboratory test to estimate iron stores. The normal value for ferritin varies according to the age and gender of the individual", "cop": 2, "opa": "Serum iron levels", "opb": "Serum ferritin levels", "opc": "Serum transferrin receptor population", "opd": "Transferrin saturation", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "c8a87315-cc05-44e9-9447-4da96008a152", "choice_type": "single"} {"question": "More than 90% of this drug is excreted in the urine intact form. Because its urinary solubilities low, patient should be well hydrated to prevent nephrotoxicity.the drug is", "exp": "Ref-KDT 6 /769 Both indinavir and acyclovir can cause nephrotoxicity and renal stone formation.but indinavir is metabolized mainly in the liver and acyclovir is excreted unchanged in the urine", "cop": 3, "opa": "Indinavir", "opb": "Zidovudine", "opc": "Acyclovir", "opd": "Amantadine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "ea17560d-d714-4cb0-a301-fdbdc70aec32", "choice_type": "single"} {"question": "M.C. site for secondary metastasis in a case of Hypernephroma", "exp": "The Renal cell Ca is prone to grow into the renal vein. Pieces of growth are swept into the circulation and end up in the lung where they grow to form cannon-ball secondary deposits. Metastasis to bone also occurs. Highly vascular metastasis may pulsate.\" Also Remember MC site of metastasis from lung Ca - Adrenals next is Liver, Brain MC site for distant metastasis from Bladder Ca - Veebrae MC site for distant metastasis from Colorectal Ca - Liver MC site for distant metastasis from Melanoma (cutaneous) - Skin/subcutanous tissue, Lung MC site for distant metastasis from Melanoma (Ocular) - Liver MC site for distant metastasis from Prostate - Bonesstas MC site for distant metastasis from Soft tissue sarcoma - Lung MC site for distant metastasis from Testis Ca - Lung MC site for distant metastasis from Thyroid Ca - Bone, Lung Metastasis to lung is most commonly from - Breast Ca Ref : Bailey & Love, 25/e p1309", "cop": 2, "opa": "Adrenal", "opb": "Lungs", "opc": "Brain", "opd": "Bones", "subject_name": "Anatomy", "topic_name": "Urology", "id": "147160b8-27c8-492d-88fd-539f7bb4a1e0", "choice_type": "single"} {"question": "Deep cardiac plexus is present at", "exp": "Deep cardiac plexus is situated in front of the bifurcation of trachea B D CHOURASIAS HUMAN ANATOMY UPPER LIMB THORAX VOLUME ,1 SIXTH EDITION, PAGE NO, 267", "cop": 1, "opa": "Tracheal bifurcation", "opb": "Myometrium", "opc": "At end of svc", "opd": "At right bronchus", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "41eede7d-a578-4bab-905a-82a31f4dca0a", "choice_type": "single"} {"question": "Muscle not in relation with structure marked A", "exp": "The marked structure is Greater trochanter. Gluteus maximus gets inserted to lliotibial tract.\nAll other 3 muscles get inserted to Greater trochanter.", "cop": 1, "opa": "Gluteus maximus", "opb": "Gluteus medius", "opc": "Gluteus minimus", "opd": "Pyriformis", "subject_name": "Anatomy", "topic_name": null, "id": "ad39752d-7766-4991-8c01-8dc8c4df6624", "choice_type": "single"} {"question": "Bleeding time assesses", "exp": "ref Robbins 8/e p666 bleeding time evaluation is used to measure the primary phase of hemostasis, which involves platelet adherence to injured capillaries and then platelet activation and aggregation. The bleeding time can be abnormal when the platelet count is low or the platelets are dysfunctional.", "cop": 4, "opa": "Extrinsic clotting pathway", "opb": "Intrinsic clotting pathway", "opc": "Fibrinogen Level", "opd": "Function of platelets", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b2ae500d-31c4-45d4-a3d1-d1993d198cbe", "choice_type": "single"} {"question": "Aery supplying major pa of superolateral surface of brain is", "exp": "The middle cerebral aery is the largest terminal branch of the internal carotid aery and it runs laterally in the lateral cerebral sulcus of the brain.It supplies the entire lateral surface of the cerebral hemisphere except the narrow strip along the superomedial border extending from the frontal pole to the parieto-occipital sulcus(which is supplied by the anterior cerebral aery) and the occipital pole and inferior temporal gyrus (both of which are supplied by the posterior cerebral aery).", "cop": 1, "opa": "Middle cerebral aery", "opb": "Anterior cerebral aery", "opc": "Posterior cerebral aery", "opd": "Veebral aery", "subject_name": "Anatomy", "topic_name": null, "id": "503d8364-58ed-4605-9726-98f814409559", "choice_type": "single"} {"question": "Number of vascular segments present in kidney are", "exp": "Five vascular segments of kidney were seen based on the branching pattern of the renal aery by angiography and corrosion cast techniques. The renalaery was divided into anterior and posterior branches.The origins of segmental aeries were variable. image Ref - eahslab.om", "cop": 1, "opa": "5", "opb": "7", "opc": "9", "opd": "11", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "49813cf5-dff2-48db-8edd-80d8e8984c48", "choice_type": "single"} {"question": "Normal platelet count is found in", "exp": "Ref Robbins 9/e p526_527 ;8/e p666;7/e p986-987 All other options have decreased platelet count except henoch schonlein purpura .though it has the name purpura ,but the platelet count in this condition is normal.The skin manifestations in HSP are due to small vessel vasculitis", "cop": 2, "opa": "Wiskott Aldrich syndrome", "opb": "Henoch schonlein purpura", "opc": "Immune thrombocytopenia", "opd": "Dengue fever", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "f0aa5707-a32e-46f8-83fa-ae39b0f7d619", "choice_type": "single"} {"question": "Angina pectoris and syncope are most likely to be associated with", "exp": "Ref Harrison 19 th ed pg 1530 patients with pure or predominant AS have gradually increas- ing obstruction over years but do not become symptomatic until the sixth to eighth decades. Adult patients with BAV disease, however, develop significant valve dysfunction and symptoms one to two decades sooner. Exeional dyspnea, angina pectoris, and syncope are the three cardinal symptoms.", "cop": 2, "opa": "Mitral stenosis", "opb": "Aoic stenosis", "opc": "Mitral regurgitation", "opd": "Tricuspid stenosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "903c92db-39d9-4375-8d01-7706cc54186e", "choice_type": "single"} {"question": "Caudal end of neuropore closes by", "exp": null, "cop": 2, "opa": "24th day", "opb": "27th day", "opc": "32nd day", "opd": "40th day", "subject_name": "Anatomy", "topic_name": null, "id": "94c7c014-834c-45ef-bfc2-98fd7f5a0937", "choice_type": "single"} {"question": "Wire loop lesions are often characteristics for the following class of lupus nephritis", "exp": "Ref Robbins illustrated 8/e p218, 9/e p224 Diffuse lupus nephritis (class IV) is the most serious form of renal lesions in SLE and is also the most commonly encountered in renal biopsies, occurring in 35% to 60% of patients. It is distinguished from focal lupus nephritis (class III) by involvement of half or more of glomeruli. Most of the glomeruli show endothelial and mesangial prolifera- tion, leading to diffuse hypercellularity of these structures (Fig. 4-18, B) and producing in some cases epithelial crescents that fill Bowman's space. When extensive, sub- endothelial immune complexes create a circumferential thickening of the capillary wall, resembling rigid \"wire loops\" on routine light microscopy (Fig. 4-18, C). Electron microscopy reveals prominent electron-dense subendo- thelial immune complexes (between endothelium and basement membrane) (Fig. 4-18, D), but immune com- plexes are also usually present in other pas of the capil- lary wall and in the mesangium. Immune complexes can be visualized by staining with fluorescent antibodies directed against immunoglobulins or complement, result- ing in a granular fluorescent staining pattern (Fig. 4-18, E). In due course, glomerular injury may give rise to scarring (glomerulosclerosis). Most affected patients have hematu- ria with moderate to severe proteinuria, hypeension, and renal insufficiency.", "cop": 3, "opa": "Mesangial proliferative glomerulonephritis(wHO class2)", "opb": "Focal proliferative glomerulonephritis (WHO class3)", "opc": "Diffused proliferative glomerulonephritis (WHO class4)", "opd": "Membranous glomerulonephritis (WHO class5)", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a7ec92fa-ba1b-4124-bd2d-c68fe9bd97fb", "choice_type": "single"} {"question": "The right adrenal vein drains into", "exp": "These blood vessels supply a network of small aeries within the capsule of the adrenal glands. Venous blood is drained from the glands by the suprarenal veins, usually, one for each gland: The right suprarenal vein drains into the inferior vena cava. ref - semantischolar.org", "cop": 2, "opa": "Right renal vein", "opb": "Inferior vena cava", "opc": "Second right lumbar vein", "opd": "Third right lumbar vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9b8a7e77-110f-4078-a443-89cab5456691", "choice_type": "single"} {"question": "Blood supply of coronoid process of mandible is primarily from", "exp": null, "cop": 2, "opa": "Inferior alveolar artery", "opb": "Deep temporal artery", "opc": "Facial artery", "opd": "Middle Meningeal artery", "subject_name": "Anatomy", "topic_name": null, "id": "95a0d0ca-aefb-4236-aca4-611c3f4e74ff", "choice_type": "single"} {"question": "Longest muscle in the body", "exp": "REF BD CHAURASIAS HUMAN ANATOMY SIXTH EDITION VOLUME 2 PAGE 53 Saorius is long narrow and ribbon like it run downwards and medially across the front of thigh .it is the longest muscle in the body. It orgin :anterior superior iliac spine Ipper half of notch below spine Inseion: medial surface of shaft of tibia upper pa", "cop": 3, "opa": "Biceps", "opb": "Triceps", "opc": "Saorius", "opd": "Quadriceps", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d38fd8a2-75de-495f-aadd-4640dd125f1b", "choice_type": "single"} {"question": "Most common cause of amoebic lung abcess", "exp": "Amoebic lung abscess is a result of direct spread of infection from liver to lung. The infection spreads directly through the diaphragm. The most common area of the lung involved is right lower lobe. The amoebic liver abscess ruptures and then it can involve any of the following structures. Right lung (Most commonly) Right pleural cavity Left Lung Pericardium Peritoneal cavity", "cop": 2, "opa": "Inhalation", "opb": "Direct extension from liver", "opc": "Hematogenous spread", "opd": "Lymphatic spread", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "715393bf-7160-4d1c-af22-76cdca995051", "choice_type": "single"} {"question": "AV node is situated in", "exp": "Koch's triangle is an anatomical area located within right atrium, defined by Ostium of coronary sinus, posteriorly The anterior-septal leaflet commissure Tendon of Todaro ( a tendinous structure connecting the valve of the inferior venacava ostium to the central fibrous body posteriorly) Used as anatomical landmark for location of AV node during electrophysiology procedures such as pacing or ablation. Ref - researchgate.net", "cop": 3, "opa": "Opening of SVC", "opb": "Interventricular septum", "opc": "Koch's triangle", "opd": "Interatrial septum", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "2bd36249-e417-460d-b9e9-d52dbfed459e", "choice_type": "single"} {"question": "On follow up study, elevated CA 125 in a case of epithelial ovarian tumour should be fuher evaluated with", "exp": "CT Scan Evaluation of patients with suspected ovarian cancer should include measurement of serum levels of the tumour marker CA-125. CA-125 determinants are glycoproteins with molecular masses from 220 to 1000 kDa, and a radioimmunoassay is used to determine circulating CA-125 antigen levels. Between 80 and 85% of patients with epithelial ovarian cancer have levels of CA-125 _ 35 U/mL. Other malignant tumours can also elevate CA-125 levels, including cancers of the endometrium, cervix, fallopian tubes, pancreas, breast, lung, and colon. Ceain nonmalignant conditions that can produce moderate elevations of CA-125 levels include pregnancy, endometriosis, pelvic inflammatory disease, and uterine fibroids. About 1% of normal females have serum CA-125 levels _35 U/mL.", "cop": 2, "opa": "MRI", "opb": "CT Scan", "opc": "Yearly follow up", "opd": "Clinical examination and serial CA 125 monitoring", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ddbac2b1-6d00-4294-b90a-22d5aec4787b", "choice_type": "single"} {"question": "Cardiac dominance is determined by coronary aery", "exp": "Cardiac dominance is determined by posterior inter ventricular aery which supplies postero inferior pa of interventricular septum. Mostly this a branch of RCA so right cardiac dominance(65% of population) If posterior inter ventricular aery arise from left coronary aery, then it is left cardiac dominance in 10% of population(bad prognosis) Multiple PIVA one from right side one from left side that is co -dominance in 25% of population.", "cop": 2, "opa": "Supplying circulation to the SA node", "opb": "Supplying circulation to the inferior poion of the interventricular septum", "opc": "Supplying circulation to the inteatrial septum", "opd": "Supplying circulation to the anterior poion of the interventricular septum", "subject_name": "Anatomy", "topic_name": "Thorax: Aerial supply", "id": "d62637e7-d31d-4483-a03c-a54011111c3a", "choice_type": "single"} {"question": "Most common viral antigen used for diagnosis of HIv", "exp": "Ref Robbins 7/e p246; 9/e p245 p24 antigen assay: It is available only as a blood test. It detects the HIV antigen called p24 plus antibodies to HIV-1 and HIV-2. ... The level of p24 antigenand the amount of virus (viral load) increase significantly soon after initial infection. Testing for p24 allows for detection of early infections, before HIV antibody is produced", "cop": 1, "opa": "P24", "opb": "P17", "opc": "P7", "opd": "P14", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7da5c167-4c6a-4888-a688-e0352446ab18", "choice_type": "single"} {"question": "Mucous membrane of cervix is lined by", "exp": "Ans: B Simple columnar epithelium(Ref: Langman's Embryology 11'h/e p. 269)Lining of uterine cavity - Ciliated columnar epithelium.Lining of cervical canal - Simple (nonciliated) columnar epithelium", "cop": 2, "opa": "Simple squamous epithelium", "opb": "Simple columnar epithelium", "opc": "Stratified squamous epithelium", "opd": "Ciliated columnar epithelium", "subject_name": "Anatomy", "topic_name": null, "id": "151a8015-eb55-4682-be2f-fa12ed63de36", "choice_type": "single"} {"question": "The ideal treatment of stenosis of sphincter of oddi is", "exp": "Sphincter of oddi dysfunction Pain similar to biliary colic with normal LFT and episodes of acute pancreatitis have been attributed to a poorly defined syndrome known as sphincter of oddi dysfunction The pathogenesis is unclear. Postulated theories include gallstone migration inducing fibrosis of the sphincter, trauma, pancreatitis and congenital anomalies Modified Milwaukee classification is used for Biliary sphincter oddi dysfunction. Treatment Treatment of choice : Transduodenal Sphinctereplasty with transampullary septectomy Ref: Sabiston 20th edition Pgno :1497", "cop": 1, "opa": "Transduodenal sphicteroplasty", "opb": "Endoscopic sphicteroplasty", "opc": "Choledochojejunostomy", "opd": "Choledochoduodenostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8c9dbef9-b1e5-449e-9c7f-9c21da83febe", "choice_type": "single"} {"question": "Feilized orum reaches the uterus", "exp": "Ans. is 'a' i.e., 3-4 days Feilized ovum (zygote) reaches the uterus in morula stage, 4 days after feilization.Feilization and implantation Feilization refers to fusion of male and female gametes (i.e. spermatozoon and ovum). It takes place in the middle segment (ampulla) of fallopian tube. Before feilization, the ovum and sperms reach the ampulla for feilization. Fusion of spermatocyte and ovum leads to formation of zygote. First week of development begins immediately after feilization and includes :?Cleavage of zygote : Zygote (feilized ovum) stas dividing immediately and large zygote is subdivided into smaller daughter cells called blastomeres. Blastomeres are still surrounded by zona pellucida. Cleavage occurs in fallopian tube (uterine tube).Formation of morula : At about 16 cells stage the blastomeres tightly align by the process of compaction to form a compact ball of cells called morula (mulberry). This process of compaction leads to segregation of cells into two groups (i) inner cells (inner cell mass), and (ii) outer cells (outer cell mass). Morula enters uterine cavity 4 days after feilization.Formation of blastocyst : As the morula enters the uterine cavity, uterine fluid diffuses through zona pellucida and fills small intercellular gaps between blastomeres, and morula is conveed to blastocyst. Blastocyst consists of :?Zona pellucida : Outer covering.Embryoblast : A group of centerally located cells of inner cell mass and later give rise to tissues of embryo proper.Trophoblast : A thin outer layer of cells formed from outer cells mass and later give rise extraembryonic tissues.Blastocele : Cavity of blastocyst :The region of blastocyst containing embryoblast is known as embryonic pole and the opposite pole, the abembryonic pole. The trophoblasts overlying the embryoblast at embryonic pole is called polar trophoblast and that occupying the rest of wall called mural trophoblast. Between 5-6 days after feilization, blastocyst hatches from zona pellucida, and this naked blastocyst is ready for implantation.Implantation : About 6-7 days after feilization the blastocyst attaches to the endometrium, a process called as implantation or embedding. Normal site of implantation is posterior wall of the body of uterus close to fundus (at junction offundus with body).", "cop": 1, "opa": "3-4 days", "opb": "6-8 days", "opc": "10-12 days", "opd": "12-14 days", "subject_name": "Anatomy", "topic_name": null, "id": "cacdea33-9432-444c-9d32-6790722323f1", "choice_type": "single"} {"question": "Unnatural sexual offences deals under", "exp": "Sec 377 IPC deals with unnatural sexual offences Whoever voluntarily has carnal knowledge against the order of nature with any man, woman, or animal shall be punished with imprisonment for life or either description for a term which may extend to ten years and shall also be liable for fine. Ref: FORENSIC MEDICINE AND TOXICOLOGY DR PC IGNATIUS THIRD EDITION PAGE 308", "cop": 3, "opa": "Sec 375 IPC", "opb": "Sec 376 IPC", "opc": "Sec 377 IPC", "opd": "Sec 379 IPC", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "3cefcb32-286c-425f-91f8-323d04c47a59", "choice_type": "single"} {"question": "Root value of long thoracic nerve", "exp": "Ans. b. C-5, 6, 7Long thoracic nerve is branch of trunk forming brachial plexus with root value of C-5, 6, 7.Dorsal scapular nerveSuprascapular nerveNerve to subclaviusLateral pectoral nerveMusculocutaneous nerveAxillary nerveMeduan nerveUlnar nerveMedial cutaneous nerve of the forearmMedial cutaneous nerve of the armRadial nerveLower subscapular nerveThoraco dorsal nerveMedial pectoral nerveUpper subscapular nerveLong thoracic nerveBranches of the plexus for the upper limbBranches of the RootsNerve to serratus anterior (Long thoracic nerve C5.6,7)Q Nerve to rhomboideus (Dorsal Scapular nerve COdeg", "cop": 2, "opa": "C-3, 4, 5", "opb": "C-5, 6, 7", "opc": "C-7, 8 T-1", "opd": "C-2, 3, 4", "subject_name": "Anatomy", "topic_name": null, "id": "415a39e2-35f5-4ebd-ad2a-7e4c962c4630", "choice_type": "single"} {"question": "Muscle not included in Anterior compartment of thigh", "exp": "Gracilis is a muscle of Medial compartment", "cop": 3, "opa": "lliacus", "opb": "Sartorius", "opc": "Gracilis", "opd": "Rectus femoris", "subject_name": "Anatomy", "topic_name": null, "id": "4d34f71e-b4cb-4b2f-b4ef-bc96bf049113", "choice_type": "single"} {"question": "Dialysis patients are prone to develop", "exp": "Can lead to anemia, osteopenia, demetia.", "cop": 4, "opa": "Iron toxicity", "opb": "Lead toxicity", "opc": "Zinc toxicity", "opd": "Aluminium toxicity", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2533011f-c536-498d-9079-78c83f035b8e", "choice_type": "single"} {"question": "Cranial nerve related to apex of the petrous temporal bone", "exp": "In the intraneural course,the fibres of VI nerve runs veically and downwardsthrough the trapezoid body,medial lemniscus and basilar pa of the pons to reach the lower border of the pons. The nerve is attached to the lower border of the pons,opposite the upper end of the pyramid of the medulla. The nerve then runs upwards,forwards and laterally through the cristerna pontis and usually dorsal to the anterior inferior cerebellar aery to reach the cavernous sinus. The ebducent nerve enters the cavernous sinus by piercing its posterior wall at a point lateral to the dorsum sellae and superior to the apex of the petrous temporal bone. As the nerve crosses the superior border of the petrous temporal bone,it passes beneath the petrosphenoidal ligament,and bends sharply forwards. In the cavernous sinus,at first it lies lateral to the internal carotid aery and then inferolateral to it. The abducent nerve enters the orbit through the middle pa of the superior orbital fissure. Here it lies inferolateral to the occulomotor and nasociliary nerves. In the orbit,the nerve ends by supplying only the lateral rectus muscle. It enters the ocular surface of the muscle. Ref BDC volume 3.6th edition pg 365", "cop": 3, "opa": "VIII", "opb": "VII", "opc": "VI", "opd": "V", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "e18be598-6d3d-4e54-a101-76ba589cc87c", "choice_type": "single"} {"question": "Nerve damaged in fracture neck fibula", "exp": "Common peroneal / fibular nerve injury: 1. The common fibular nerve is susceptible to injury as it passes around the lateral aspect of the neck of the fibula. 2. It can be result of direct trauma. Secondary to knee injury or as a consequence of proximal fibular fracture, sometimes can be iatrogenic (Ex. Ahroscopy) 3. Symptoms of CPN injury. Foot drop Loss of sensation over the lateral aspect of leg & dorsum of foot Wasting of fibular & anterior Tibial muscle.", "cop": 3, "opa": "Superficial peroneal", "opb": "Deep peroneal", "opc": "Common peroneal", "opd": "Tibial", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "8bedc336-ffbf-4bae-8691-123245924f89", "choice_type": "single"} {"question": "Stapedius muscle is upplied by …..Nerve", "exp": null, "cop": 1, "opa": "Facial", "opb": "Vagus", "opc": "Glossopharyngeal", "opd": "Trochlear", "subject_name": "Anatomy", "topic_name": null, "id": "37d8d0b9-3204-4fac-9900-38979e1f1627", "choice_type": "single"} {"question": "Vidian nerve passes through", "exp": "In the anterior pa of the foramen lacerum,the greater petrosal nerve unites with the deep petrosal nerve to form the nerve of the pterygoid canal(the vidian nerve)which leaves the foramen by entering the pterygoid canal in the anterior wall of the foramen lacerum. REF.BDC VOL.3,FIFTH EDITION", "cop": 4, "opa": "Inferior orbital fissure", "opb": "Incisive foramen", "opc": "Tympanomastoid fissure", "opd": "Pterygoid canal", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "7a97bb87-da0c-432f-af2c-83f6130ae1b9", "choice_type": "single"} {"question": "Valvulae conniventes are seen in", "exp": "The valvulae conniventes, also known as Kerckring folds or plicae circulares, are the mucosal folds of the small intestine, staing from the second pa of the duodenum, they are large and thick at the jejunum and considerably decrease in size distally in the ileum to disappear entirely in the distal ileal bowel loops. p Ref - radiopedia.org", "cop": 1, "opa": "Jejunum", "opb": "Ileum", "opc": "Stomach", "opd": "Colon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "49860c53-f494-45ba-ae72-f62ac3234dd0", "choice_type": "single"} {"question": "Right coronary sinus directly drains into", "exp": "The coronary sinus is the largest vein of the hea.It is situated in the left posterior coronary sulcus.It is about 3cm long.It ends by opening into the posterior wall of the right atrium.It receives the following tributaries such as the great cardiac vein,the middle cardiac vein,the small cardiac vein,the posterior vein of the left ventricle,the oblique vein of the left atrium of Marshall and the right marginal vein. REF.B D Chaurasia's human anatomy vol.1,fifth edition", "cop": 4, "opa": "SVC", "opb": "IVC", "opc": "Circumflex aery", "opd": "Right atrium", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "49d1aa2e-9d7c-4432-b3ac-7f318ddaebf1", "choice_type": "single"} {"question": "Danger area of neck is situated between", "exp": "The space between Alar fascia & Preveebral fascia proper is called danger area as the infection or pus in this place can spread to posterior mediastinum.", "cop": 3, "opa": "Buccopharyngeal and preveebral fascia", "opb": "Pharyngobasilar and preveebral fascia", "opc": "Preveebral and alar fascia", "opd": "Buccopharyngeal and alar fascia", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "103f7132-cb80-45af-82df-4ef679b9f477", "choice_type": "single"} {"question": "Wegeners Granulomatosis", "exp": "All options are Crct Refer Robbins page no 511 Wegeners Granulomatosis is treated with steroids and cycloohosphamide. They dramatically ameliorate glomerular injury in pauci immune glomerulonephritis", "cop": 1, "opa": "Involves lungs", "opb": "Involves nose", "opc": "Involves kidney", "opd": "Treated with cytotoxic agent /steroids", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "9cadeed3-34f0-4e05-8f95-edddb559bb84", "choice_type": "single"} {"question": "Gene for eye morphogenesis", "exp": "Ans. is 'a' i.e., Pax-6The Pax-6 gene locus is a transcription factor for various genes and growth factors involved in eye formation.Pax-6 is a master control gene for eye morphogenesis and encodes for Paired box protein Pax-6 (also called aniridia type II protein or oculorhombin).", "cop": 1, "opa": "Pax-6", "opb": "BMP-4", "opc": "HOX-D13", "opd": "HOX-A13", "subject_name": "Anatomy", "topic_name": null, "id": "8f44a572-9dcb-43e4-83d9-8ace83a5ba80", "choice_type": "single"} {"question": "After meiotic division, the primary oocyte remains arrested in", "exp": "At the time of bih all primary oocyte are in the prophase of meiotic division The primary oocyte remain in prophase and complete their first meiotic divison until they mature and ready to ovulate Human embryology Tenth edition Inderbier Singh Page 24", "cop": 1, "opa": "Diplotene stage", "opb": "Pachytene stage", "opc": "Metaphase", "opd": "Telophase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4a840d86-e415-4e14-a7a1-63b5c2435006", "choice_type": "single"} {"question": "The lingual surface of epiglottis is lined by", "exp": null, "cop": 1, "opa": "Stratified squamous epithelium", "opb": "Simple squamous epithelium", "opc": "Stratified columnar epithelium", "opd": "Pseudostratified epithelium", "subject_name": "Anatomy", "topic_name": null, "id": "e112db95-c01d-4fd5-8882-e81ade95b328", "choice_type": "single"} {"question": "The gastroduodenal aery is derived from", "exp": "The gastroduodenal aery is the branch of the common hepatic aery. It passes inferiorly behind the 1st pa of the duodenum and bifurcates into right gastroepiploic aery and superior pancreaticoduodenal aery. Gastroduodenal aery provides blood to the distal pa of the stomach, the duodenum proximal poion and to pancreatic head indirectly through the posterior and anterior and superior pancreaticoduodenal aery. Ref -BDC vol2 6e pg 277", "cop": 2, "opa": "Celiac aery", "opb": "Hepatic aery", "opc": "Splenic aery", "opd": "Cystic aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "d60a4e22-2d0f-4c86-a634-c9a14f5e1b89", "choice_type": "single"} {"question": "Thyroarytenoid muscle causes", "exp": "Thyroarytenoid muscle is relaxor of vocal cord. Vocalis muscle which is medial fibre of thyroarytenoid, causes tension in anterior ⅓ and relaxation in posterior ⅔ of vocal cord.", "cop": 3, "opa": "Adduction of vocal cord", "opb": "Tenses vocal cord", "opc": "Relaxes vocal cord", "opd": "Closes inlet of larynx", "subject_name": "Anatomy", "topic_name": null, "id": "0fc29d23-3e2f-40ff-9b63-2366fbfde6f4", "choice_type": "single"} {"question": "The paracentral lobule is located in", "exp": "The paracentral lobule is a gyrus on the medial surface of the cerebral hemisphere. It is present in the motor area of frontal lobe where representation is upside down. The areas for the legs and perineum lie in the paracentral lobule.Ref: BD Chaurasia; volume 3; 6th edition; Brain; page no: 378", "cop": 1, "opa": "Medial surface of cerebral hemisphere", "opb": "Superolateral surface of cerebral hemisphere", "opc": "Tentorial surface of cerebral hemisphere", "opd": "Orbital surface of cerebral hemisphere", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "6b5ad1dd-76a3-4a2c-a331-8a0d2fe36b5c", "choice_type": "single"} {"question": "The narrowest pa of the larynx is", "exp": "The rima has an anterior intermembranous pa (three-fifth) and a posterior intercailaginous pa, The rima is the narrowest pa of the larynx. It is longer (23 mm) in males than in females (17 mm ). ref : B D Chaurasia's Human Anatomy , sixth edition, volume 3 , pg. no. 256 ref : 16.15a , B D Chaurasia's Human Anatomy , sixth edition, volume 3 , pg. no. 255", "cop": 4, "opa": "Ventricle", "opb": "Vestibule", "opc": "Subglottic space", "opd": "Glottis", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d147caa9-0423-4fd8-b383-e6bf26f7f1a1", "choice_type": "single"} {"question": "The epitheliod cell and multinucleated giant cells of granulomatous inflammation are derived from", "exp": "Ref Robbins 9/e p97 Delayed type of hypersensitivity results from accumulation of mononucleated cells around small veins and venules producing a perivascular cuffing .mono cytes transform into macrophages which undergo morphological changes to produce epitheliod cell", "cop": 4, "opa": "Basophils", "opb": "Eosinophil", "opc": "CD4T lymphocytes", "opd": "Monocytes marcophages", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "244718e8-402f-464d-89f5-393f607a49a6", "choice_type": "single"} {"question": "Tear drop bladder is seen in", "exp": "In case of extra peritoneal rupture of bladder a cystogram shows extravasation of contrast material into the pelvis around the base of bladder. The characteristic TEAR DROP' deformity represents bladder compression by a large pelvic haematoma. Ref : Schwaz 7/e p1803", "cop": 3, "opa": "Hunner's ulcer", "opb": "Tuberculosis", "opc": "Perivisceral hemorrhage with rupture", "opd": "Perivisceral hemorrhage without rupture", "subject_name": "Anatomy", "topic_name": "Urology", "id": "20e5d732-176a-4420-aa83-37ef80c1d312", "choice_type": "single"} {"question": "The most impoant source of histamine", "exp": "ref Robbins 8/e p57,9/e p83 Histamine is synthesized in all tissues, but is paicularly abundant in skin, lung and gastrointestinal tract. Mast cells, which are present in many tissues, are a prominentsource of histamine, but histamine is also secreted by a number of other immune cells.", "cop": 1, "opa": "Mast cells", "opb": "Eosinophil", "opc": "Neutrophils", "opd": "Macrophages", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4ecc504c-a051-4cc3-8aa3-5caa32b565be", "choice_type": "single"} {"question": "The artery marked X is most commonly a branch of", "exp": "X marked structure is Right Gastric artery which is most commonly a branch of Hepatic artery proper", "cop": 3, "opa": "Common Hepatic Artery", "opb": "Superior pancreaticoduodenal Artery", "opc": "Hepatic artery proper", "opd": "Gastroduodenal artery", "subject_name": "Anatomy", "topic_name": null, "id": "17f1b859-24a3-42c9-9f83-7077921dac9e", "choice_type": "single"} {"question": "Gerlach tonsil in Waldayer's ring is", "exp": "Ans. is 'a' i.e., Tubal tonsil", "cop": 1, "opa": "Tubal tonsil", "opb": "Palatine tonsil", "opc": "Pharyngeal tonsil", "opd": "Lingual tonsil", "subject_name": "Anatomy", "topic_name": null, "id": "fbe34a04-ccd0-439a-aa36-73501c77d2d0", "choice_type": "single"} {"question": "Nerve roots involved at the Erb's point are", "exp": "Erb's ParalysisThe site of injury: One region of the upper trunk of the brachial plexus is called Erb's point. Six nerves meet here. Injury to the upper trunk causes Erb's paralysis. Nerve roots involved; Mainly C5 and paly C6.Muscles paralyzed: Mainly biceps brachii, deltoid, brachialis, and brachioradialis. Paly supraspinatus, infraspinatus, and supinator. Deformity and position of the limbArm: Hangs by the side; it is adducted and medially rotated.Forearm: Extended and pronated.The deformity is known as policeman's tip hand' or waiter's tip hand or'poer's tip hand'. Disability: The following movements are lost: Abduction and lateral rotation of the arm at the shoulder joint.Flexion and supination of the forearm.Biceps and supinator jerks are lost.Sensations are lost over a small area over the lower pa of the deltoid. Ref: Chaurasia; Volume 1; 6th edition; Page no: 56", "cop": 1, "opa": "C5, C6", "opb": "C5, C7", "opc": "C6, C7", "opd": "C7, C8", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f03f7b36-a978-4028-9bfa-c5fdc03d9949", "choice_type": "single"} {"question": "45 year old alcoholic male came for deaddiction treatment. He has alcohol induced hepatitis with other blood parameters within normal limits. The drug that should not be chosen for relapse prevention is", "exp": "NALTREXONE is an OPIOID ANTAGONIST given at a dosage of 50-150mg, should not be used in LIVER DYSFUNCTION ACAMPROSATE is an GABA AGONIST given at a dosage of 666MG TDS, should not be used in KIDNEY DYSFUNCTION Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no.626", "cop": 3, "opa": "Disulfiram", "opb": "chlordiazepoxide", "opc": "Naltrexone", "opd": "Acamprosate", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "bb7fbaff-f870-41e5-80cd-07817e09eb62", "choice_type": "single"} {"question": "Testicular lymphatics drain into", "exp": "Lymphatic drainage of the testes follows the testicular aeries back to the paraaoic lymph nodes, while lymph from the scrotum drains to the inguinal lymph nodes. Ref: BD Chaurasia; 6th edition", "cop": 3, "opa": "Deep inguinal lymphnodes", "opb": "Internal iliac lymph nodes", "opc": "Para aoic lymph nodes", "opd": "Superficial inguinal lymphnodes", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "562dec8f-04e7-48cc-b13e-a6e2a43d03cf", "choice_type": "single"} {"question": "Mantoux test reading of less than 5mm indicates", "exp": "Ref Robbins 9/e p371 Mantoux test is simply able to predict the presence or absent of cell mediated immunity against the tubercular antigens .it cannot differentiate between infection and disease Negative mantoux test just indicates that the individual has not been exposed to tuberculin bacilli", "cop": 2, "opa": "Tuberculosis infection", "opb": "Disseminated TB", "opc": "Susceptiblity to TB", "opd": "Immunity to TB", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2f2b9b1e-61f7-45cb-a653-76e70b1b4583", "choice_type": "single"} {"question": "Parotid duct opens", "exp": "The duct runs forwards for a sho distance between the buccinator and the oral mucosa. Finally, the duct turns medially and opens into the vestibule of the mouth opposite to the crown of upper second molar tooth. REF.BDC SIXTH EDITION VOL NO:3 PAGE NO:110", "cop": 2, "opa": "Opposite 1st mollar", "opb": "Opposite 2nd molar", "opc": "Into the papilla", "opd": "Opposite incisor", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f047ee18-f447-432a-adb7-e83f36b1bf43", "choice_type": "single"} {"question": "Muscle of neck with dual nerve supply", "exp": "Digastric muscle Digastric has two bellies United by an intermediate tendon. NERVE SUPPLY; anterior belly by nerve to mylohyoid, facial nerve. ACTIONS; 1. Depresses mandible is opened widely or against resistance it is secondary to lateral pterygoid. 2. Elevates hyoid bone. Ref BDC volume 3;6th edition", "cop": 3, "opa": "Sternohyoid", "opb": "Thyrohyoid", "opc": "Digastric", "opd": "Stylohyoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "40365dc8-e675-4a98-9608-40793707d848", "choice_type": "single"} {"question": "Embryological development of the human veebra is form", "exp": "The paraxial mesoderm becomes segmented to form 40-45 pairs of somites that lie on either side of the developing neural tube and notochord. The somites appear between the 20th and 30th days of development. Hence, the 4th week of development is known as somite period of development. The veebral column is formed from the sclerotomes of the somites. The cells of each sclerotome get conveed into loose mesenchyme. This mesenchyme migrates medially and surrounds the notochord. REF: Inderbir Singh's Human Embryology, eleventh edition, pg. no., 138, 139.", "cop": 1, "opa": "Somite", "opb": "Endoderm", "opc": "Ectoderm", "opd": "neuroectoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "507ef2c0-77d3-48fb-b6fe-61b78762d239", "choice_type": "single"} {"question": "Aery in anatomical snuffbox is", "exp": "Radial nerve along with superficial branch of radial nerve and cephalic vein are the contents of anatomical snuff box.Brachial aery passes from medial side of arm to its anterior aspect.Ulnar aery passes over the flexor retinaculum in the forearm.B D Chaurasia 7th edition Page no: 136", "cop": 1, "opa": "Radial", "opb": "Brachial", "opc": "Ulnar", "opd": "Interosseous", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "76b1d094-6050-439e-97c4-63052ddf91c1", "choice_type": "single"} {"question": "Laparoscopic cholecystectomy was done, on histopathology, stage was T2. Next line of treatment", "exp": "Treatment of carcinoma Gallbladder Gallbladder cancer: Incidental pathological finding after laparoscopic cholecystectomy T1a with negative cystic duct margin : No fuher therapy T1a with postive cystic duct margin : Reresection of cystic duct or CBD to negative margin T1b, T2, T3 tumor with no evidence of metastasis : Reresection, extended cholecystectomy (possible CBD or extended hepatic resection) T4: Extended cholecystectomy with extended right hepatectomy N2 or M1 disease : Clinical trial (Chemoradiation or chemotherapy) in good performance status. Laparoscopic trocar site scars are excised for staging purpose to identify M1 disease than for any potential therapeutic benefit Ref: Sabiston 20th edition Pgno : 1512-1514", "cop": 2, "opa": "Observation", "opb": "Extended cholecystectomy", "opc": "Po size excision", "opd": "Chemotherapy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2ec7d89e-7877-4a9f-9576-b8cfe72d8aa4", "choice_type": "single"} {"question": "Muscle attached to the marked area", "exp": "Masseter arises from zygomatic arch and inses onto lateral aspect of ramus and angle of the mandible.Its innervated by the masseteric nerve from the anterior division of the mandibular nerve.Action is to elevate and protract the angle of the mandible", "cop": 1, "opa": "Masseter", "opb": "Temporalis", "opc": "Medial pterygoid", "opd": "Lateral pterygoid", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "1d98a361-2e15-4c79-a166-454cef96fd6a", "choice_type": "single"} {"question": "IV fluid replacement (volume & rate) in a trauma patient is determined by", "exp": "Urine output \"Urine output is a quantitative and relatively reliable indicator of organ perfusion. Adequate urine output is 0.5 ml/kg/ h in an adult, lml/kg/h in a child and 2ml/kg/h in an infant less than 1yr. of age.\" Pulse- Although tachycardia may be the earliest sign of hypovolemia, individuals in good physical condition, and paicularly trained atheletes with a low resting pulse rate, may manifest only a relative tachycardia, pts on blocking medication may not be able to increase their hea rate. In children, bradycardia or relative bradycardia can occur with severe blood loss. Conversely, hypoxia, pain, apprehension and stimulant drugs produce a tachycardia\" Blood pressure Hypotension is not a reliable early sign of hypovolemia. in healthy pts. Blood volume must decrease by 30 to 40 percent before hypotension occurs. Younger pts with good sympathetic tone can maintain systemic blood pressure with severe intravascular deficit untill they are on the verge of cardiac arrest. CVP(Central venous pressure) CVP measurement helps in distinguishing b/w cardiogenic shock and hypovolemic shock. 'A central venous catheter can give information about the relationship b/w intravascular volume and right ventricular function but should not be used to assess either factor independently. Ref: Sabiston 20th edition Pgno : 555 Bailey and love 27th edition Pgno :17", "cop": 2, "opa": "CVP", "opb": "Urine output", "opc": "BP", "opd": "Blood Hb", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "0ae8d932-69cf-4344-b6a1-e53f8ad8b31c", "choice_type": "single"} {"question": "Great vein of Galen is formed by", "exp": "(A) Two internal cerebral veins # GALEN'S VEINS: The internal cerebral veins; the great vein of Galen is formed by their union.> Anterior cerebral vein also known as Galen's vein.> Great cerebral vein or Great vein of Galen is formed by union of two internal cerebral veins. It terminates in the straight sinus.", "cop": 1, "opa": "Two internal cerebral veins", "opb": "Superficial middle cerebral vein & deep middle cerebral vein", "opc": "Anterior cerebral vein & basal vein", "opd": "Internal cerebral veins & straight sinus", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "d93d70a3-b830-4a91-b637-9fe618391310", "choice_type": "single"} {"question": "Gluteus medius muscle is supplied by", "exp": "C i.e. Superior gluteal aery", "cop": 3, "opa": "Obturator aery", "opb": "Ilio-inguinal aery", "opc": "Superior gluteal aery", "opd": "Inferior gluteal aery", "subject_name": "Anatomy", "topic_name": null, "id": "6f3d6b84-e0a5-4386-a3fe-2855bf8a454e", "choice_type": "single"} {"question": "Internal carotid artery at the bifurcation from the common carotid is", "exp": null, "cop": 1, "opa": "Lateral to the external carotid.", "opb": "Medial to external carotid.", "opc": "Posterior to external carotid.", "opd": "Anterior to external carotid.", "subject_name": "Anatomy", "topic_name": null, "id": "9b5c08eb-b559-4a50-bf6c-c38ee7cdbd38", "choice_type": "single"} {"question": "Shedding of red tears seen in", "exp": "OP poisoning Pupils will be usually constricted and will be pin point. In the eye, the ciliary muscles are constricted. So the suspensory ligaments are relaxed and the lens will bulge to the anterior chamber. So there will be blurring of vision. There may be lacrimation and in severe cases, chromo-lachryorrhoea (shedding of red tears) This is due to accumulation of porphyrin in the lacrimal glands due to inhibition of porphyrin metabolism, one of the minor actions of some organophosphates especially marathon. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 448", "cop": 3, "opa": "Alcohol poisoning", "opb": "Phosphorus poisoning", "opc": "OP poisoning", "opd": "Lead poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "27580ea5-3bc9-42ba-b57f-f4fcb3cbebd9", "choice_type": "single"} {"question": "Profound MR the IQ is below", "exp": "Just learn the IQ ranges", "cop": 3, "opa": "50", "opb": "40", "opc": "20", "opd": "10", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c7341768-4e3f-4beb-9de2-6392448109be", "choice_type": "single"} {"question": "Example of traction epiphysis is", "exp": "Traction epiphysis is nonaicular and does not take pa in transmission of weight. It always provides attachment to one or more tendons which exe a traction on epiphysis. Traction epiphyses ossify later than pressure epiphyses Eg:Trochanters of femur and tubercles of humerus Description Ref BD CHAURASIA S Handbook of General Anatomy Fouh edition Pg no 41", "cop": 1, "opa": "Trochanters of long bone", "opb": "Os trigonum", "opc": "Carpals", "opd": "Coracoid process", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9a1ccb6c-51c7-4506-aa0d-9f88c8d5c882", "choice_type": "single"} {"question": "Green nail syndrome is caused by", "exp": "It is a paronychia ( inflammation of the tisseues adjacent to the nail with green pus formation) . It results from prolonged submersion of the hands in water.", "cop": 1, "opa": "Psedomonas aeruginosa", "opb": "Pleisomonas", "opc": "Aeromonas", "opd": "Burkholderia", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "19b89c94-801e-4315-ae86-f62b6cd06060", "choice_type": "single"} {"question": "Nerve supply to the muscles of flexor compament of arm", "exp": "MUSCULOCUTANEOUS NERVE:- Nerve of front of arm. Arises from lateral cord of brachial plexus in the axilla. Runs downwards and laterally, pierces the corcobrachialis, which it supplies, then passes between biceps and brachialis. Descends over the lateral aspect of forearm as lateral cutaneous nerve of forearm. Branches:- 1. Muscular:- biceps brachii, coracobrachialis and brachialis. 2. Cutaneous- lateral cutaneous nerve of forearm. 3. Aicular branch-elbow joint. {Reference: vishram singh, pg no. 108}", "cop": 3, "opa": "Radial nerve", "opb": "Median nerve", "opc": "Musculocutaneous nerve", "opd": "Ulnar nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a8967827-f073-4f4e-947b-d73aa5c7fe60", "choice_type": "single"} {"question": "Anterior lymphatics from nose drain into", "exp": "Lymphatics from the anterior half of the lateral wall pass to the submandibular nodes, and from the posterior half, to the retropharyngeal and upper deep cervical nodes Anterior half of Nasal septum to the submandibular nodes. Posterior half of nasal septum to the retropharyngeal and deep cervical nodes . Ref - BDC vol3 6th e pg 242-246", "cop": 3, "opa": "Pretracheal nodes", "opb": "Submandibular nodes", "opc": "Deep cervical nodes", "opd": "Submental nodes", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "30d077b5-aa00-4e24-8779-9e0d9b99e31d", "choice_type": "single"} {"question": "Least common presentation of HCC", "exp": "On rare occasions, HCC can present as a rupture with the sudden onset of abdominal pain followed by hypovolemic shock secondary to intraperitoneal bleeding Other rare presentations include hepatic vein occlusion (Budd-Chiari syndrome), obstructive jaundice, hemobilia or fever of unknown origin(PUO) Ref: Sabiston 20th edition Pgno : 1459", "cop": 1, "opa": "PUO", "opb": "Mass", "opc": "Jaundice", "opd": "Weakness", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "37f40939-4a90-41fe-b32e-f17938e9a193", "choice_type": "single"} {"question": "Scarpa's fascia is attached to", "exp": "The fascia of Scarpa is the deep membranous layer, of the superficial fascia of the abdomen. It is a layer of the anterior abdominal wall. It is found deep to the Camper Fascia and superficial to the external oblique muscle. Ref - BDC 6e vol2 pg199", "cop": 3, "opa": "Inguinal ligament", "opb": "Pubic crest", "opc": "Fascia lata of thigh", "opd": "Conjoint tendon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e40f00d9-fbfe-493d-9bdf-7ce01dd81f1c", "choice_type": "single"} {"question": "T.U.R. (transurethral resection) syndrome is due to", "exp": "TUR syndrome and water intoxication syndrome are same. They are caused due to dilutional hyponatremia. Ref : Bailey & Love 25/e p1352", "cop": 1, "opa": "Hyponatremia", "opb": "Hypokalemia", "opc": "Hypovolaemia", "opd": "Hypoxia", "subject_name": "Anatomy", "topic_name": "Urology", "id": "44140bbc-a88a-4a92-a544-10990f13e741", "choice_type": "single"} {"question": "Traction epiphysis is are", "exp": "Traction epiphysis are usually present at the end if bones and develop due to traction by the attached muscle (and are therefore extracapsular), eg Greater (and lesser) tubercle in humerus and greater ( and lesser) trochanter in femur Ref: Gray's39e/p185-210", "cop": 2, "opa": "Head of humerus", "opb": "Lesser tubercle", "opc": "Deltoid tuberosity", "opd": "Ciracoid process", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94c3e97b-c88c-4c4b-8941-e0cf47d25ea2", "choice_type": "single"} {"question": "Most common cause of pseudopancreatic cyst in children is", "exp": "Pancreatic pseudocyst follows acute attack of pancreatitis and trauma is the most common cause of acute pancreatitis in children. Most common causes of acute pancreatitis in children include: Blunt abdominal injuries, Mumps and other viral illnesses Congenital anomolies Ref : Nelson 16/e, p 1300", "cop": 4, "opa": "Chloledochal cyst", "opb": "Annular pancreas", "opc": "Drug induced pancreatitis", "opd": "Traumatic pancreatitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "65960ced-a879-4e74-8e4e-e71cfa6a0ef3", "choice_type": "single"} {"question": "Defenition of Rape is defined under section", "exp": "Sec 375 IPC defines rape Sec 376 IPC is explaining the punishment of rape. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 298", "cop": 4, "opa": "Sec 374 IPC", "opb": "Sec 376A IPC", "opc": "Sec 376B IPC", "opd": "Sec 375 IPC", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "d203db17-e597-4b0b-b36c-b56d75513a75", "choice_type": "single"} {"question": "Dermatome at umbilicus is", "exp": "Dermatome level of umbilicus is T 10. Dermatome of Epigastric level is T7 Dermatome of Supra pubic level is L1.", "cop": 2, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "L1", "subject_name": "Anatomy", "topic_name": "Mesentry, neurovascular bundle", "id": "d132d264-3b53-47ec-ab0d-4163667c0295", "choice_type": "single"} {"question": "Blood supply of thoracic part of esophagus", "exp": "Blood supply of thoracic part of oesophagus is aorta.", "cop": 1, "opa": "Aorta", "opb": "Inferior thyroid artery", "opc": "Gastric artery", "opd": "Superior thyroid artery", "subject_name": "Anatomy", "topic_name": null, "id": "99c9ab0d-6c89-433e-8286-2c7aa3a359ef", "choice_type": "single"} {"question": "Most common site of Morgagni Hernia is", "exp": "More common in right side and lies between the pericardium and right pleura. B D CHAURASIA&;S HUMAN ANATOMY LOWER LIMB ABDOMEN AND PELVIS VOLUME-2,SIXTH EDITION Page no-334", "cop": 3, "opa": "Left Anterior", "opb": "Right posterior", "opc": "Right Anterior", "opd": "Left posterior", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "4bcf10be-b651-426b-b217-80ea03685801", "choice_type": "single"} {"question": "Thickening of the respiratory membrane is seen in", "exp": "Thickening of the airway wall is a feature of airways remodeling and is seen in asthma A condition in which a person's airways become inflamed, narrow and swell and produce extra mucus, which makes it difficult to breathe.", "cop": 1, "opa": "A. Asthma", "opb": "B. Emphysema", "opc": "C. Empyema", "opd": "Bronchiectasis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "5c5a219f-9bf4-484a-b139-a4a3b749778a", "choice_type": "single"} {"question": "Cutaneous innervations of dorsum of foot are marked in the given diagram. The area D supplied by", "exp": "Common peroneal nerve wind around the neck of fibula and divide into superficial and deep peroneal nerve Superficial peroneal nerve (musculo cutaneous nerve of lower limb) - supplies peroneus longus and brevis Deep peroneal nerve - supplies extensor compament of leg CHOICE EXPLANATION & ELIMINATION REASON 1 B - area supplied by deep peroneal nerve 2 D - area supplied by superficial peroneal nerve 3 C - area supplied by sural nerve 4 Not correct", "cop": 2, "opa": "Deep peroneal nerve", "opb": "Superficial peroneal nerve", "opc": "Tibial nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": "Nerve supply of Lower Limb", "id": "43a40644-73eb-4796-a552-ec87c21968ff", "choice_type": "single"} {"question": "One of the following opens into middle meatus of nose", "exp": "The middle meatus presents the ethmoidal bulla,the hiatus semilunaris,the infundibulum and the opening of frontal,maxillary and the middle ethmoidal air sinuses.Sphenoidal air sinus opens into the sphenoethmoidal recess,which is a triangular fossa just above the superior concha. REF.BDC VOL.3,5th edition.", "cop": 4, "opa": "Naso-lacrimal duct", "opb": "Eustachian tube", "opc": "Sphenoidal sinus", "opd": "Maxillary sinus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1689e380-6561-4524-b6fe-60fee5a48566", "choice_type": "single"} {"question": "MELD score doesn't include", "exp": "MELD score (CBI) : Creatinine, Bilirubin, INR PELD score(NABIA) : Nutritional status, Age, Bilirubin, INR, Albumin Ref: Sabiston 20th edition Pgno : 658", "cop": 4, "opa": "INR", "opb": "Serum Bilirubin", "opc": "Serum creatinine", "opd": "Blood urea", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7c105b82-6c91-4704-b0c2-40e320e2c5ea", "choice_type": "single"} {"question": "CD 95 has a major role in", "exp": ".", "cop": 1, "opa": "Apoptosis", "opb": "Cell necrosis", "opc": "Interferon activation", "opd": "Proteolysis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "133dc2dd-6062-43d9-bac5-27b92e5c5e1f", "choice_type": "single"} {"question": "The role played by major histocompatibility complex 1 and 2", "exp": "Ref Robbins 8/e p191 Class I MHC molecules are encoded by three closely linked loci, designated HLA-A, HLA-B, and HLA-C (Fig. 4-3). Each of these molecules is a heterodimer, con- sisting of a polymorphic 44-kDa a chain noncovalently associated with an invariant 12-kDa b2-microglobulin polypeptide (encoded by a separate gene on chromo- some 15). The extracellular poion of the a chain contains a cleft where the polymorphic residues are located and where foreign peptides bind to MHC mol- ecules for presentation to T cells, and a conserved region that binds CD8, ensuring that only CD8+ T cells can respond to peptides displayed by class I molecules. In general, class I MHC molecules bind and display pep- tides derived from proteins synthesized in the cyto- plasm of the cell (e.g., viral antigens). Because class I MHC molecules are present on all nucleated cells, all virus-infected cells can be detected and eliminated by CD8+ CTLs. Class II MHC molecules are encoded by genes in the HLA-D region, which contains at least three subregions: DP, DQ, and DR. Class II MHC molecules are heterodi- mers of noncovalently linked polymorphic a and b sub- units (Fig. 4-3). The extracellular poion of the class II MHC heterodimer contains a cleft for the binding of antigenic peptides and a region that binds CD4. Class II MHC expression is restricted to a few types of cells, mainly APCs (notably, dendritic cells ), macro- phages, and B cells. In general, class II MHC molecules bind to peptides derived from proteins synthesized outside the cell (e.g., those derived from extracellular bacteria) and ingested into the cell. This propey allows CD4+ T cells to recognize the presence of extracellular pathogens and to orchestrate a protective response. * Several other proteins are encoded in the MHC locus, some of which have been called \"class III molecules.\" These include complement components (C2, C3, and Bf) and the cytokines tumor necrosis factor (TNF) and lymphotoxin. These molecules do not form a pa of the peptide display system and are not discussed fuher.", "cop": 3, "opa": "Transduce the signal to T cells following antigen recognition", "opb": "Mediate immunogenic class switching", "opc": "Present antigens for recognition by T cells antigen receptor", "opd": "Enhance the secretion of cytokine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "25040b2f-b7f2-4d29-8a4f-cbd8451b91ac", "choice_type": "single"} {"question": "Following is an example of", "exp": ".", "cop": 2, "opa": "Coagulative necrosis", "opb": "Fat necrosis", "opc": "Liquefactive necrosis", "opd": "Fibrinoid necrosis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "42ff000d-32b7-4a49-b169-3c526ae288fc", "choice_type": "single"} {"question": "Position of nucleus ambiguous is", "exp": "Nucleus ambiguous lies at the level of olives in medulla, posterolateral to olives.It lies deep within the reticular formation and gives origin to the motor fibres of 9,10 and 11 cranial nerves. Along the posterolateral sulcus emerges the rootlets of 9,10and11 cranial nerves.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 73, fig 8.2)", "cop": 4, "opa": "Anteromedial to olive", "opb": "Anterolateral to olive", "opc": "Posteromedial to olive", "opd": "Posterolateral to olive", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "115b5b32-585e-4731-b57b-f98370df28c8", "choice_type": "single"} {"question": "Indication for PAIR treatment in hydatid cyst", "exp": "PAIR Puncture, aspiration, injection and reaspiration IIt is the preferred method of treatment for anatomically and surgically appropriate lesions Contraindication - complicated cysts ( communicating with biliary tract) surgery remains the treatment of choice for those not possible or refractory to PAIR", "cop": 1, "opa": "Size >5 cm", "opb": "Multiloculated", "opc": "Cyst in lung", "opd": "Recurrence after surgery", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6e7b29ae-420f-4108-8301-1057ba48aba1", "choice_type": "single"} {"question": "Structure passing through foramen Rotundum is", "exp": "The foramen rotundum: it leads posteriorly to the pterygopalatine fossa containing pterygopalatine ganglia. Maxillary nerve passes throgh the foramen rotundum. Ref BDC volume:3,6th edition", "cop": 3, "opa": "Ophthalmic nerve", "opb": "Mandibular nerve", "opc": "Maxillary nerve", "opd": "Abducens nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "925814ed-c122-4abd-8a8c-5a22b8af426e", "choice_type": "single"} {"question": "Proptosis is seen in", "exp": "B option is also correct Neuroblastoma metastasizes in the orbit causing Proptosis Refer khurana 6/e", "cop": 1, "opa": "Neuroblastoma", "opb": "Meningioma", "opc": "Sympathetic Ophthalmia", "opd": "Injuries", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "21eea28e-cf97-4c3f-8d4d-f2b096cd297a", "choice_type": "single"} {"question": "Apthous ulcers are also known as", "exp": "Refer Robbins page no 728 9/e Chronic recurrent oral aphthous ulcers are the most common type of inflammatory efflorescence of the oral mucosa, with a prevalence of 2% to 10% in Caucasian populations. To treat them properly, physicians should know their clinical appearance and course, conditioning factors, underlying causes, and differential diagnosis. Results Hard, acidic, and salty foods and toothpastes containing sodium lauryl sulfate should be avoided, along with alcohol and carbonated drinks. In Germany, the only drugs that have been approved to treat oral aphthous ulcers are coicosteroids, topical antiseptic/anti-inflammatory agents such as triclosan and diclofenac, and local anesthetics such as lidocaine. Antiseptic agents and local anesthetics should be tried first; if these are ineffective, topical coicosteroids should be used. In severe cases, local measures can be combined with systemic drugs, e.g., colchicine, pentoxifylline, or prednisolone. The efficacy of systemic treatment is debated. Other immunosuppressive agents should be given systemically only for refractory or paicularly severe oral aphthous ulcers due to Adamantiades-Behcet disease", "cop": 1, "opa": "Canker sores", "opb": "Marjolins ulcer", "opc": "Curling s ulcer", "opd": "Cushings ulcer", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "695cbc72-882b-4424-accc-486ef0ff1eb5", "choice_type": "single"} {"question": "Injury to dangerous area of face infection goes to", "exp": "(Cavernous sinus) (195-BDC-3) (544.581-small 9th)Facial infections and cavernous sinus ThrombosisThe area of facial skin bounded by the nose, the eye, and two upper lip is a potentially dangerous zone to have an infection, for example, a boil in this region can cause thrombosis of two facial vein. With spread of organisms through two inferior ophthalmic vein to the cavernous sinus, the resulting cavernous sinus thrombosis may be fatal unless adequately treated with antibioticsDangerous area of face includes the upper LipQ, and the Lower part of NoseQ.It is called the 'dangerous area' as infections from this region can spread in a retrograde direction from the face to the cavernous sinus causing dangerous complications like 'thrombosis of the cavernous sinusFacial vein can communicate to the cavernous sinus through two major routes or deep connections i.e.-Important Structures Associated with the cavernous sinuses# The internal carotid artery and the 6th cranial nerve which travel through it# In the lateral wall, the 3rd and 4th cranial nerve and the ophthalmic and maxillary division of the 5th cranial nerve# The pituitary gland which lies medially in the sella turcica# The veins of the face, which are connected with the cavernous sinus via the facial nerve and inferior ophthalmic vein, are an important route for the spread of infection from the face# The superior and inferior petrosal sinuses which run along the upper and lower border of the petrous part of the temporal one Cavernous sinus lesions presentation |||Nervous symptomsVenous symptoms| ||| Pain in the distribution of ophthalmic (V1) and Maxillary (V2) nerveParalysis of extra ocular muscles due to lesion affecting III IV & VI cranial nerveMarked oedema of the eyelids, cornea and roof of nose with exophthalmos due to congestion of orbital veins CAVERNOUS SINUS|Incoming channels Draining channels* Superior ophthalmic vein *** Inferior ophthalmic vein *** Central vein of Retina *** (may drain via superior ophthalmic vein)* Superficial middle cerebral vein **** Inferior cerebral vein ** Sphenoparietal sinus ** Middle meningeal vein *( frontal and Anterior Trunk) * Superior petrosal sinus (drain into Transverse sinus)* Inferior petrosal sinus (drain into internal jugular vein) **** Emissary veins *** (drain into pterygoid plexus of veins)* Superior ophthalmic vein (drain into facial vein)* Inter cavernous vein (\"sinuses communicate between the left & right cavernous sinuses", "cop": 1, "opa": "Cavernous sinus", "opb": "Mastoiditis", "opc": "Labyrinthitis", "opd": "Lateral sinus thromophlebitis", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "ac00ce6b-cbf7-4ad4-91c6-e338f8fe34a3", "choice_type": "single"} {"question": "In acute pulmonary embolism the most frequent ECG finding is", "exp": "The ECG is often normal but is useful in excluding other impoant differential diagnoses, such as acute myocardial infarction and pericarditis. The most common findings in PE include sinus tachycardia and anterior T-wave inversion but these are non-specific; larger emboli may cause right hea strain revealed by an S1Q3T3 pattern, ST-segment and T-wave changes, or the appearance of right bundle branch block. Aerial blood gases typically show a reduced PaO2 and a normal or low PaCO2, and an increased alveolar-aerial oxygen gradient, but may be normal in a significant minority. A metabolic acidosis may be seen in acute massive PE with cardiovascular collapse. An elevated D-dimer is of limited value, as it may be raised in a variety of other conditions, including myocardial infarction, pneumonia and sepsis. However, low levels, paicularly in the context of a low clinical risk, have a high negative predictive value and fuher investigation is usually unnecessary . The result of the D-dimer assay should be disregarded in high-risk patients, as fuher investigation is mandatory even when normal. The serum troponin I may be elevated, reflecting right hea strain. Ref Davidson edition23rd pg 620", "cop": 3, "opa": "S1Q3T3 pattern", "opb": "P.pulmonale", "opc": "Sinus tachycardia", "opd": "Right Axis detion", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "8c7b897d-d8a1-4281-91b9-ea2a769c8055", "choice_type": "single"} {"question": "aplastic anemia is the side effect of", "exp": "Carbamazepine - SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential Ref. Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no.935", "cop": 2, "opa": "valproate", "opb": "carbamezepine", "opc": "lamotrigine", "opd": "lithium", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "a21f4e5d-2d2b-4cea-8048-e38e6d54ff8d", "choice_type": "single"} {"question": "Transient bells palsy during mandibular nerve block after injection of local anesthesia occurs due to needle piercing into", "exp": null, "cop": 4, "opa": "Maxillary artery", "opb": "Buccinator muscle", "opc": "Temporalis muscle", "opd": "Parotid gland", "subject_name": "Anatomy", "topic_name": null, "id": "6035466a-8398-49be-8ace-b1ef3a400c95", "choice_type": "single"} {"question": "Notochord develops in", "exp": "(A) 3rd week > Notochord develops in 3rd week.", "cop": 1, "opa": "3rd week", "opb": "3rd month", "opc": "6 months", "opd": "10th week", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "bc3847d2-7217-4076-b0e5-82a07619cc80", "choice_type": "single"} {"question": "Number of Hepatic segments in Liver", "exp": "The Couinaud classification of liver anatomy divides the liver into eight functionally independent segments.Each segment has its own vascular inflow, outflow and biliary drainage.In the centre of each segment, there is a branch of the poal vein, hepatic aery and bile duct.Reference: Chaurasia Volume II; 7th edition; Page no: 336", "cop": 3, "opa": "4", "opb": "6", "opc": "8", "opd": "10", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "83572973-88ae-4a24-af5c-a3e391a7e28c", "choice_type": "single"} {"question": "Regulation of blood flow is maintained by", "exp": "(Refer: Ganong's Review of Medical Physiology 24thedition, pg no: 570-572, 577)", "cop": 4, "opa": "Aeries", "opb": "Venules", "opc": "Capillaries", "opd": "Aerioles", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "869c5c34-e9ab-4533-8b39-7923074198ea", "choice_type": "single"} {"question": "Example of type 2 hypersensitivity is", "exp": "Ref Robbins 9/e p206 Antibody-Mediated Diseases (Type II Hypersensitivity) Antibody-mediated (type II) hypersensitivity disorders are caused by antibodies directed against target antigens on the surface of cells or other tissue components. The antigens may be normal molecules intrinsic to cell membranes or in the extracellular matrix, or they may be adsorbed exoge- nous antigens (e.g., a drug metabolite). Antibody-mediated abnormalities are the underlying cause of many human diseases; examples of these are listed in Table 4-3. In all of these disorders, the tissue damage or functional abnormali- ties result from a limited number of mechanisms. Mechanisms of Antibody-Mediated Diseases Antibodies cause disease by targeting cells for phagocyto- sis, by activating the complement system, and by interfer- ing with normal cellular functions (Fig. 4-10). The antibodies that are responsible typically are high-affinity antibodies capable of activating complement and binding to the Fc receptors of phagocytes. * Opsonization and phagocytosis. When circulating cells, such as erythrocytes or platelets, are coated (opsonized) with autoantibodies, with or without complement pro- teins, the cells become targets for phagocytosis by neutrophils and macrophages (Fig. 4-10, A). These phagocytes express receptors for the Fc tails of IgG anti- bodies and for breakdown products of the C3 comple- ment protein, and use these receptors to bind and ingest opsonized paicles. Opsonized cells are usually elimi- nated in the spleen, and this is why splenectomy is of Table 4-3 Examples of Antibody-Mediated Diseases (Type II Hypersensitivity) clinical benefit in autoimmune thrombocytopenia and some forms of autoimmune hemolytic anemia. * Inflammation. Antibodies bound to cellular or tissue anti- gens activate the complement system by the \"classical\" pathway (Fig. 4-10, B). Products of complement activa- tion serve several functions (see Fig. 2-18, Chapter 2), one of which is to recruit neutrophils and monocytes, triggering inflammation in tissues. Leukocytes may also be activated by engagement of Fc receptors, which rec- ognize the bound antibodies. This mechanism of injury is exemplified by Goodpasture syndrome and pemphi- gus vulgaris. * Antibody-mediated cellular dysfunction. In some cases, antibodies directed against cell surface receptors impair or dysregulate cellular function without causing cell injury or inflammation (Fig. 4-10, C). In myasthenia gravis, antibodies against acetylcholine receptors in the motor end plates of skeletal muscles inhibit neuromuscular transmission, with resultant muscle weakness. Antibodies can also stimulate cellular Figure 4-10 Mechanisms of antibody-mediated injury. A, Opsonization of cells by antibodies and complement components, and ingestion of opso- nized cells by phagocytes. B, Inflammation induced by antibody binding to Fc receptors of leukocytes and by complement breakdown products. C, Antireceptor antibodies disturb the normal function of receptors. In these examples, antibodies against the thyroid-stimulating hormone (TSH) receptor activate thyroid cells in Graves disease, and acetylcholine (ACh) receptor antibodies impair neuromuscular transmission in myasthenia g responses excessively. In Graves disease, antibodies against the thyroid-stimulating hormone receptor stim- ulate thyroid epithelial cells to secrete thyroid hormones, resulting in hypehyroidism. Antibodies against hor- mones and other essential proteins can neutralize and block the actions of these molecules, causing functional derangements.", "cop": 1, "opa": "Blood transfusion reaction", "opb": "Ahur reaction", "opc": "Hay fever", "opd": "Post streptococcal glomerulonephritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d22fdd5f-d568-415b-a8bb-69b321809a70", "choice_type": "single"} {"question": "Middle cerebellar Penducle transmits..... fibres", "exp": "A i.e. Pontocerebellar", "cop": 1, "opa": "Ponto cerebellar pathway", "opb": "Tectospinal pathway", "opc": "Spino cerebellar pathway", "opd": "Middle cerebellar pathway", "subject_name": "Anatomy", "topic_name": null, "id": "2c8fcaa8-8235-426e-a805-43cb3c3ecaa9", "choice_type": "single"} {"question": "ACL prevents", "exp": "Anterior cruciate ligament prevents Posterior dislocation of femur on tibia Anterior displacement of tibia on femur Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 1394.", "cop": 4, "opa": "Anterior displacement of fibula", "opb": "Posterior displacement of tibia", "opc": "Anterior displacement of femur", "opd": "Posterior displacement of femur", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "15ef7e48-1d2a-497f-9266-8b9428d0c759", "choice_type": "single"} {"question": "The most likely precursor to bronchiectasis is", "exp": "BronchiectasisAbnormal and permanent dilatation of bronchi.The bronchial dilatation of bronchiectasis of is associated with destructive and inflammatory changes in the walls of medium-sized airways, often at the level of segmental or subsegmental bronchi.Types of bronchiectasisCylindrical bronchiectasis Varicose bronchiectasis Saccular (cystic) bronchiectasis Aetiology & pathogenesisBronchiectasis is a consequence of inflammation and destruction of the structural components of the bronchial wall. Infection is the usual cause of inflammation.Adenovirus and influenza virusImpaired host defence mechanisms Carcinoid tumours or foreign body aspirationPrimary ciliary dyskinesia, Kaagener&;s syndrome and cystic fibrosis are also associated with bronchiectasis.Exposure to toxic substances like inhalation of toxic gases such as ammonia or aspiration of acidic gastric contentsClinical Manifestations:Radiographic findingsPersistent or a recurrent cough and purulent sputum productionHemoptysis due to bleeding from friable, inflamed airway mucosa.Massive bleeding from hyperophied bronchial aeries.Physical examination include crackles, rhonchi, and wheeze may be heard, all of which reflect the damaged airway containing significant secretions HRCT is an investigation of choice When seen longitudinally, the airways appears as\"tram tracks\"; when seen in cross-section, they produce&;ring shadows\" Bronchiectasis of relatively proximal airways suggests ABPA, whereas the presence of multiple small nodules (nodular bronchiectasis) suggest infection with M. avium complex(Refer: Harrison's Principles of Internal Medicine, 18thedition, pg no: 2143-2144)", "cop": 4, "opa": "Tuberculosis", "opb": "Carcinoma", "opc": "Bronchial adenoma", "opd": "Bronchopneumonia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "a93cf1bd-dcf3-4782-babf-52b0e4651318", "choice_type": "single"} {"question": "The skin over the xiphoid process is innervated by the following thoracic spinal nerve", "exp": "The skin over the xiphoid is innervated by the thoracic spinal nerve from T6. The anterior chest wall is innervated by the lateral cutaneous branches and anterior cutaneous branches of the intercostal nerves. Intercostal nerves T7 to T11 and the subcostal nerve T12 supply the skin and muscle of the abdominal wall. In addition, T5 and T6 supply the upper pas of the external oblique muscle of the abdominal wall. The highest thoracic dermatome on the anterior chest wall is T2. Ref: Gray's Anatomy 41st edition Pgno: 945", "cop": 2, "opa": "T4", "opb": "T6", "opc": "T9", "opd": "T10", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d6193496-3c33-4d8d-a3e3-b4341fc58222", "choice_type": "single"} {"question": "Glomus cells are found in", "exp": "The glomus cells (type I) are specialized glandular-like cells, mainly located in the carotid bodies and aoic bodies, that control the respiratory activity.The glomus cells have a high metabolic rate and good blood perfusion and synapses directly or indirectly with nerve endings. Thus are sensitive to changes in aerial blood gas (specially to low pO2)(Ref: Guyton & hall, pg- 367)", "cop": 3, "opa": "Bladder", "opb": "Brain", "opc": "Chemoreceptors", "opd": "Kidney", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "dd614810-d6b1-42e1-a3f5-4cff4ddc9a4e", "choice_type": "single"} {"question": "Reverse splitting Of first hea sound is heard in", "exp": "Ref Harrison 19 th ed pg 1447 Reversed or paradoxical splitting refers to a pathologic delay in aoic valve closure, such as that which occurs in patients with left bundle branch block, right ventricular pac- ing, severe AS, HOCM, and acute myocardial ischemia. With reversed or paradoxical splitting, the individual components of S2 are audible at end expiration, and their interval narrows with inspiration, the oppo- site of what would be expected under normal physiologic conditions.", "cop": 2, "opa": "RBBB", "opb": "LBBB", "opc": "Tricuspid stenosis", "opd": "AR", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c73b6182-328b-4f76-96f9-d4e6188653ad", "choice_type": "single"} {"question": "The main antagonistic muscle of rectus abdominis muscle is", "exp": "The rectus abdominus muscle reflexes the trunk/lumbar spine, therefore it is a antagonist muscles should extend the spine. The erector spinae muscles are a group of muscles that perform this functions.These can be divided up it into individual muscles. The erector spinae muscles lies on the each side of the veebral column.and extends along the lumbar, thoraxic and cervical sections of the spine.It straightens the back and provide side to side rotation. Ref - researhgate.net", "cop": 4, "opa": "Psoas major", "opb": "Latissimus dorsi", "opc": "Quadratus lumborum", "opd": "Erector spinae", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "75a7de5c-8f16-4313-b098-1534323e1112", "choice_type": "single"} {"question": "Gold standard test for investigation for chronic Pancreatitis detection of early pathologies and simultaneous treatment possible (e.g., duct dilation, stent inseion) Ductal stones, seen as filling defects \"Chain of lakes\" or \"string of pearls\" appearance (characteristic feature) Irregularity, dilation of the main pancreatic duct", "exp": "ERCP - Considered the gold standard for the diagnosis of CP, the advent of secretion MRCP and EUS have significantly decreased its role as a diagnostic test ERCP : detection of early pathologies and simultaneous treatment possible (e.g., duct dilation, stent inseion) Ductal stones, seen as filling defects\"Chain of lakes\" or \"string of pearls\" appearance (characteristic feature)Irregularity, dilation of the main pancreatic duct Ref: Sabiston 20th edition Pgno :1535", "cop": 2, "opa": "MRI", "opb": "ERCP", "opc": "Pancreatic function tests", "opd": "Fecal fat estimation", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2297c368-9cd3-441b-88fd-ec5679590cf1", "choice_type": "single"} {"question": "Roof of Anatomical snuff box is related to", "exp": "The name 'snuff box' originates from the use of this surface for placing and then sniffing powdered tobacco, or \"snuff\" Anatomical Snuffbox boundaries Lateral wall Abductor pollicis longus (APL) Extensor pollicis brevis (EPB) Medial Wall Extensor pollicis longus (EPL) Roof Cephalic vein Superior branch of radial nerve Floor Radial styloid, scaphoid, Trapezium and 1st Metacarpal Only content: Radial aery. Ref: Gray's Anatomy 41st edition Pgno: 893", "cop": 3, "opa": "Radial aery", "opb": "Basilic vein", "opc": "Superior Branch of radial nerve", "opd": "Superior branch of ulnar nerve", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b8884bc0-d69c-49e2-addd-7ec5ab3dcb4b", "choice_type": "single"} {"question": "Oncocytic carcinoma arises from", "exp": "Refer Robbins 8/e p964, 9/ep953 Oncocytoma This is an epithelial neoplasm composed of large eosinophilic cells having small, round, benign-appearing nuclei that have large nucleoli. It is thought to arise from the intercalated cells of collecting ducts, and accounts for approximately 5% to 15% of renal neoplasms. Ultra-structurally the eosinophilic cells have numerous mitochondria. In gross appearance, the tumors are tan or mahogany brown, relatively homogeneous, and usually well encapsulated with a central scar in one-third of cases. However, they may achieve a large size (up to 12 cm in diameter). There are some familial cases in which these tumors are multicentric rather than solitary.", "cop": 4, "opa": "Perivascular tissue", "opb": "Glomerulus", "opc": "Loop of henle", "opd": "Collecting duct", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "1ba26e3f-6200-4a55-8a70-846d5a5df7a1", "choice_type": "single"} {"question": "Skin and facia of great toe drains into", "exp": "The superficial inguinal lymph nodes form a chain immediately below the inguinal ligament. They lie deep to Camper&;s fascia which overlies the femoral vessels at medial aspect of the thigh. They are found in the triangle bounded by the inguinal ligament superiorly, the border of the saorius muscle laterally, and the adductor longus muscle medially. (Femoral Triangle of Scarpa) There are approximately 10 superficial lymph nodes. The superficial nodes drain to the deep inguinal lymph nodes.", "cop": 1, "opa": "Veical group of superficial inguinal lymph node", "opb": "Horizontal group of superficial inguinal lymph node", "opc": "Obturator lymph nodes", "opd": "Deep inguinal lymph nodes", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e6d3571a-d5e6-4daf-8949-fafb06981f51", "choice_type": "single"} {"question": "duration criteria for anorexia nervosa is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "5 months", "opb": "3 months", "opc": "2 months", "opd": "4 months", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "4b41298f-027f-40ab-92dc-44409ee5d88d", "choice_type": "single"} {"question": "The axillary nerve supplies", "exp": "Teres minor is supplied by the posterior division of axillary nerve which is characterized by the presence of a pseudoganglion. Posterior division of axillary nerve also supplies the posterior pa of deltoid muscle. B D Chaurasia 7th edition Page no : 180", "cop": 2, "opa": "Infraspinatus", "opb": "Teres minor", "opc": "Trapezius", "opd": "Pectoralis major", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f1ebde74-9b9d-4dd2-ac74-dadbc769b533", "choice_type": "single"} {"question": "The cavernous sinus does not communicate with the", "exp": null, "cop": 3, "opa": "Opthalmic vein", "opb": "Internal jugular vein", "opc": "External jugular vein", "opd": "Pterygoid plexus", "subject_name": "Anatomy", "topic_name": null, "id": "04129e79-23f3-4f63-85e5-602e5acc7b60", "choice_type": "single"} {"question": "A congenital diaphragmatic hernia may result from failure of the", "exp": "The formation of the diaphragm occurs through the fusion of tissue from four different sources. The pleuroperitoneal membranes normally fuse with the three other components during week 6 of development. Abnormal development or fusion of one or both of the pleuroperitoneal membranes causes a patent opening between the thorax and abdomen through which abdominal viscera may herniate. fig:- development of diaphragm", "cop": 2, "opa": "Septum transversum to develop", "opb": "Pleuroperitoneal membranes to fuse in a normal fashion", "opc": "Pleuropericardial membrane to develop completely", "opd": "Dorsal mesentery of the esophagus to develop", "subject_name": "Anatomy", "topic_name": "Umblicial cord and diaphragm", "id": "dd72739f-cb58-46ed-8c22-356bf464cc8d", "choice_type": "single"} {"question": "Stroma of cornea is developed from", "exp": "Stroma of cornea develops from neural crest cells derived (secondary) mesenchyme. The adult cornea has developmentally three layers: Outer epithelium layer (surface ectoderm) Middle stromal layer of collagen-rich extracellular matrix between stromal keratocytes (neural crest) Inner layer of endothelial cells (neural crest). Ref - medscape.com", "cop": 3, "opa": "Neural ectoderm", "opb": "Surface ectoderm", "opc": "Mesoderm", "opd": "Neural crest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "be728c78-6881-4937-834c-c5c5f84b4cb3", "choice_type": "single"} {"question": "The normal P wave is inveed in lead", "exp": "Since this vector points toward the positive pole of lead II and toward the negative pole of lead aVR, the normal P wave will be positive in lead II and negative in lead aVR Ref Harrison 20th edition pg 1456", "cop": 4, "opa": "LI", "opb": "LII", "opc": "aVF", "opd": "aVR", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5c82bbfd-7b2c-4061-9c7d-427294d95b3f", "choice_type": "single"} {"question": "anorexia nervosa is assosiated with", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "admit in severe cases", "opb": "metabolic yndrome", "opc": "overweight", "opd": "obesity", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "0b1852c2-8167-41d1-b2c9-ab9bb6fe70d6", "choice_type": "single"} {"question": "A lesion involving upper motor neuron of facial nerve manifests as", "exp": "The facial muscles are innervated by the facial nerve. Damage to the facial nerve in the internal acoustic meatus (by a tumor), in the middle ear (by infection or operation), in the facial nerve canal (perineuritis, Bell's palsy), or in the parotid gland (by a tumor) or caused by lacerations of the face will cause distoion of the face, with drooping of the lower eyelid, and the angle of the mouth will sag on the affected side. This is essentially a lower motor neuron lesion. Check voluntary movement of the upper pa of the face on the affected side: in supranuclear lesions such as a coical stroke (upper motor neuron; above the facial nucleus in the pons), the upper third of the face is spared while the lower two thirds are paralyzed. The orbicularis, frontalis, and corrugator muscles are innervated bilaterally, which explains the pattern of facial paralysis in these cases", "cop": 4, "opa": "Upper half of the face is affected, lower half normal", "opb": "Left half of the face", "opc": "Right half of the face", "opd": "Upper half of the face normal, lower half affected", "subject_name": "Anatomy", "topic_name": null, "id": "4a33e358-ac0d-482f-b668-d3afbc013361", "choice_type": "single"} {"question": "The simple columnar or cuboidal epithelium lining the extrahepatic biliary ducts is derived from", "exp": "liver gall bladder and biliary apparatus develop from an endodermal diveiculum that arises from ventral aspect of terminal forgut The epithelium lining the extrahepatic biliary ducts is derived from endoderm. The intrahepatic biliary ducts are also derived from endoderm.", "cop": 2, "opa": "Mesoderm", "opb": "Endoderm", "opc": "Ectoderm", "opd": "Neuroectoderm", "subject_name": "Anatomy", "topic_name": "Embryology and abdominal wall layer", "id": "1d46bcdd-8e7d-4256-af9a-6ad91bc33d60", "choice_type": "single"} {"question": "Palsy of right genioglossus causes", "exp": "Palsy of right genioglossus muscle detes the tongue to the right side, due to unopposed medial pull of the left genioglossus. Genioglossus muscle moves the tongue anterior (protrusion), inferior (depression) and medial (AIM). In bilateral contraction of genioglossus, the vector of medial pull is balanced (and cancelled), and there occurs protrusion and depression of tongue in midline.", "cop": 1, "opa": "Detion of tongue to right", "opb": "Detion of tongue to left", "opc": "Detion of soft palate to right", "opd": "Detion of soft palate to left", "subject_name": "Anatomy", "topic_name": "Cranial Nerves", "id": "8264e6d4-9edd-4674-b258-28f0bb609db7", "choice_type": "single"} {"question": "a super antigen is a bacterial product that", "exp": "Ref Harrison 16/e p1920 Superantigens (SAgs) are a class of antigens that result in excessive activation of the immune system. Specifically it causes non-specific activation of T-cellsresulting in polyclonal T cell activation and massive cytokine release. SAgs are produced by some pathogenic viruses and bacteria most likely as a defense mechanism against the immune system.Compared to a normal antigen-induced T-cellresponse where 0.0001-0.001% of the body's T-cells are activated, these SAgs are capable of activating up to 20% of the body's T-cells. Fuhermore, Anti-CD3and Anti-CD28 Antibodies (CD28-SuperMAB) have also shown to be highly potent superantigens (and can activate up to 100% of T cells).", "cop": 2, "opa": "Binds to B7 and CD 8 co stimulatory molecules", "opb": "Binds to beta chain of TCR and MCH class 2 molecules at APC stimulating T cell activation", "opc": "Binds to CD4 molecules causing TCells activation", "opd": "Is presented by macrophages to a larger than normal number of T helper CD4 lymphocytes", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8f3c10eb-c1a1-473f-8b9b-72542fc40e39", "choice_type": "single"} {"question": "The aery to the ductus dererens is a branch of", "exp": "The vas deferens is supplied by an accompanying aery (aery of vas deferens). This aery normally arises from the superior (sometimes inferior) vesical aery, a branch of the internal iliac aery. Ref - researchgate.net", "cop": 3, "opa": "Inferior epigastric aery", "opb": "Superior epigastric aery", "opc": "Superior vesical aery", "opd": "Cremasteric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "d81402e7-c5b4-4231-966b-b71b6fd7f6f1", "choice_type": "single"} {"question": "Isolated gastric varices", "exp": "Most common cause of gastric varices : Cirrhosis Most common cause of isolated gastric varices : Splenic vein thrombosis Ref: Sabiston 20th edition Pgno : 1232", "cop": 2, "opa": "Profuse bleeding", "opb": "Most commonly due to splenic vein thrombosis", "opc": "EUS is better than endoscopy", "opd": "Single treatment can lead to eradication", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "4d9be23f-8e01-4c23-958e-139d3f1d8e00", "choice_type": "single"} {"question": "Occipital myotome gives", "exp": "The muscles of the tongue develop from myoblasts that migrate into developing tongue from the occipital myotomes. The hypoglossal nerve-the nerve of the occipital myotomes-accompanies the myoblasts during their migration to the pharyngeal arches and innervates the muscle of the tongue as they develop. The migration of the occipital myotomes to the tongue explains the course of the hypoglossal nerve. The laryngeal muscles develop from 4th and 6th pharyngeal arches The muscles of mastication from the first arch. The muscles of facial expression from the second arch. Reference: Textbook of clinical embryology,1st edition, Vishram Singh, page no.123,112", "cop": 2, "opa": "Muscle of mastication", "opb": "Tongue muscles", "opc": "Facial muscles", "opd": "Laryngeal muscles", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "5f9afc45-08c8-4b6c-a4ad-70c5c5c2ae5e", "choice_type": "single"} {"question": "Parofollicular cells develops from", "exp": "Parafolliculor cells derived from neural crest and ultino - brachail body.\nNeural crest is the best option.", "cop": 4, "opa": "Ultimo - bractial body", "opb": "Pharyngeal pouch 4", "opc": "Pharyngeal pouch 3", "opd": "Neural crest cells", "subject_name": "Anatomy", "topic_name": null, "id": "98f21f49-6c68-4824-b82e-873e2c1df627", "choice_type": "single"} {"question": "Purkinje cells from the cerebellum end in", "exp": "The output of purkinje cells is inhibitory to the cerebellar nuclei", "cop": 2, "opa": "Cerebral coex", "opb": "Cerebellar nuclei", "opc": "Cranial nerve nuclei", "opd": "Extrapyramidal system", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7e5895b5-90d2-411a-a93d-150b43ef8a7d", "choice_type": "single"} {"question": "Hypoglossal nerve is", "exp": null, "cop": 2, "opa": "Purely sensory", "opb": "Purely motor", "opc": "Mixed", "opd": "Spinal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "5d926920-bedb-4487-ae30-53fe5329f44c", "choice_type": "single"} {"question": "The etiological agent of Roseola infantum includes", "exp": "Roseola infantum*A history of 3 days of high-grade fever in an otherwise nontoxic 10-month-old child with a blanchable maculopapular rash on trunk -Roseola.*Mean duration- 6days - so sixth disease/Exanthem subitum.*Nagayama spots-ulcers at the uvulopalatoglossal junction.*DD - Measles, Rubella, Drug allergy.*M/C complication-convulsions / recurrent seizures/temporal lobe epilepsy.*Rx suppoive*Severe cases-Ganciclovir/ Foscarnet.(Refer: Nelson's Textbook of Paediatrics, 19thedition, pg no:1117)", "cop": 4, "opa": "CMV", "opb": "EBV", "opc": "Parvovirus", "opd": "Human herpes virus 6", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "71139f31-2a44-43b6-b001-4dee2bdbf0b8", "choice_type": "single"} {"question": "Middle Third of the IJV lies at the cervical lymph node level", "exp": null, "cop": 3, "opa": "Level I", "opb": "Level II", "opc": "Level III", "opd": "Level IV", "subject_name": "Anatomy", "topic_name": null, "id": "b8f816ee-e11a-4d49-8880-08395985f3ef", "choice_type": "single"} {"question": "Daughter cells formed from the cleavage of zygote are", "exp": "Zygote first divide into blastomere, 16 cell stage is known as Morula.", "cop": 4, "opa": "Morula", "opb": "Gastrula", "opc": "Blastula", "opd": "Blastomere", "subject_name": "Anatomy", "topic_name": null, "id": "90640c30-3b46-410a-b7f5-836a176a82a1", "choice_type": "single"} {"question": "Pogonion is present on", "exp": "Pogonion is anterior most point on chin.", "cop": 4, "opa": "Submentum in neck", "opb": "Hyoid bone", "opc": "Lowest point on mandible symphysis", "opd": "Anterior most point on contour of chin", "subject_name": "Anatomy", "topic_name": null, "id": "5cddfcc5-7b97-49c5-a74a-c7aa740756a4", "choice_type": "single"} {"question": "Most common site of ectopic pancreatic tissue is", "exp": "Ectopic pancreatic tissue, also known as heterotopic pancreatic tissue, refers to the presence of pancreatic tissue in the submucosal, muscularis or subserosal layers of the luminal gastrointestinal tract outside the normal confines of the and lacking any anatomic or vascular connection with the main pancreas. Recognized locations for ectopic pancreatic tissue include: proximal proximal jejunum ", "cop": 1, "opa": "Stomach", "opb": "Jejunum", "opc": "Appendix", "opd": "Hilum of spleen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9438f9a0-8611-482c-9b64-30bc2fdb266e", "choice_type": "single"} {"question": "Sensory supply for upper part of right cheek is by", "exp": "Maxillary division of trigeminal Nerve supplies Upper lip; side and ala of nose; most of the lower eyelid; upper part of cheek; and anterior part of temple.", "cop": 2, "opa": "Opthalmic nerve", "opb": "Maxillary nerve", "opc": "Mandibular nerve", "opd": "Cervical plexus", "subject_name": "Anatomy", "topic_name": null, "id": "66f5cce0-fc04-4524-bbae-252c62cdc1ed", "choice_type": "single"} {"question": "Cardiac polyp is seen in", "exp": "Chicken fat and red current jelly seen in post moem clot", "cop": 4, "opa": "Acute nephritis", "opb": "Endocarditis", "opc": "Septicaemia", "opd": "Postmoem clot", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "03f7c9c2-7ec9-471c-ace8-a1093f79e913", "choice_type": "single"} {"question": "Protrusion of tongue not possible in damage of", "exp": "ACTIONS OF EXTRINSIC MUSCLES OF TONGUE: Hyoglossus-Depress the tongue Styloglossus-Retracts the tongue Palatoglossus-Elevates the tongue Genioglossus-Protrudes the tongue NOTES: Genioglossus muscle is a life-saving muscle Ref BDC volume 3,sixth edition pg 266", "cop": 4, "opa": "Styloglossus", "opb": "Hypoglossus", "opc": "Palatoglossus", "opd": "Genioglossus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "88d0e4ea-e724-43cc-ae7f-0864a5985b49", "choice_type": "single"} {"question": "Not a feature of CBD stone", "exp": "Clinical features of CBD stone CBD stone may be silent and are often discovered incidentally. In these patients, biliary colic, jaundice, clay coloured stools and darkening of the urine Fever and chills may be present in patients with choledocholithiasis and cholangitis Serum bilirubin, aminotransferases, and ALP are commonly elevated in patients with biliary obstruction but are neither sensitive nor specific for the presence of common duct stones Among these, serum bilirubin has the highest positive predictive value for the presence of choledocholithiasis Laboratory values may be normal in one third of Patients with choledocholithiasis Ref: Sabiston 20th edition Pgno:1494", "cop": 4, "opa": "Pain", "opb": "Jaundice", "opc": "Fever", "opd": "Septic shock", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "22d8f1ef-33b7-4891-8fc6-c340279202b3", "choice_type": "single"} {"question": "The primordia of the craniofacial complex develops from", "exp": null, "cop": 1, "opa": "Hensen's node", "opb": "Notochordal process", "opc": "Cloacal membrane", "opd": "Blastopore", "subject_name": "Anatomy", "topic_name": null, "id": "e531c607-eace-4b2a-b18e-b08db4377529", "choice_type": "single"} {"question": "Among the following, content of cavernous sinus is", "exp": "Structures passing through the medial aspect of the sinus: Internal carotid aery -with the venous and sympathetic plexus around it Abducent nerve- inferolateral to the internal carotid aery. Notes: Structures within the lateral wall of the sinus from above downwards: Oculomotor nerve Trochlear nerve Ophthalmic nerve Maxillary nerve Trigeminal ganglion. Ref BDC volume3,sixth edition of 193", "cop": 4, "opa": "Maxillary division of trigeminal nerve", "opb": "Ophthalmic division of trigeminal nerve", "opc": "Trochlear nerve", "opd": "Internal carotid aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "2fd8ade5-df1a-489c-804e-60560d7565fe", "choice_type": "single"} {"question": "Syndesmosis is a type of", "exp": "Sutures, syndosmosis and gomphosis are the types of Fibrous joint.", "cop": 1, "opa": "Fibrous", "opb": "Plain", "opc": "Pivot", "opd": "Cartilaginous", "subject_name": "Anatomy", "topic_name": null, "id": "3dad24e8-be9e-4d7b-a431-308d6c29a170", "choice_type": "single"} {"question": "Ulnar collateral nerve is", "exp": "In the arm, the radial nerve is posterior to the brachial aery. Here it gives muscular branches to long and medial heads of triceps brachii. The branch for medial head lies very close to the ulnar nerve and hence is called the ulnar collateral nerve. ReferenceClinicall Anatomy for students, a problem-solving approach, Neeta v Kulkarni, 2nd edition, page no.179", "cop": 2, "opa": "Branch of ulnar nerve", "opb": "Branch of radial nerve supplying medial head of triceps", "opc": "Branch of radial nerve supplying long head of biceps", "opd": "Branch of radial nerve supplying lateral head of triceps", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "8ffad3c0-3b5d-4058-a68a-b539e1e705f2", "choice_type": "single"} {"question": "WRONG about ileum as compared with jejunum is", "exp": "Jejunum has long and sparse vasa recta as compared to ileum. Jejunum are thick walled and peritoneal windows are transparent as compared to ileum. Peyer patches are present in ileum which are absent in jejunum. Jejunum have 1 or 2 rows of aerial arcades whereas ileum have 4 to 5 aerial arcades Ileum have sho club shaped villi. Ileum have more fat in mesentry.", "cop": 2, "opa": "Sho club shaped Villi", "opb": "Long vasa recta", "opc": "More lymphoid nodules", "opd": "More fat in mesentery", "subject_name": "Anatomy", "topic_name": "Small and Large intestine", "id": "7de409bf-cd0a-429d-bd32-cc73478b5fe4", "choice_type": "single"} {"question": "A patient presented with weakness of the right side of the face. There is associated ipsilateral loss of pain and temperature of face and contralateral body. The lesion is most likely located at", "exp": "Lesion in pons leads to7th nerve palsyas 7th nerve nucleus is present in Pons leading to I/L facial weakness along impairment ofsensory pa of 5th nerve(Present laterally in Pons) leading to I/L loss of sensations on face. As the pain and temp. sensation of left side (C/L) is also affected s/o oflesion to spino-thalamic tractwhich runs laterally. In case of lateral medullary syndrome or wallenburg syndrome, all the symptoms mentioned above will be present. Along with those, there will be impairment of VIII, IX, X and XI CN.", "cop": 2, "opa": "Medial medulla", "opb": "Lateral pons", "opc": "Medial pons", "opd": "Lateral medulla", "subject_name": "Anatomy", "topic_name": "NEET Jan 2020", "id": "e544e72c-5d6e-465e-be14-484d2f646368", "choice_type": "single"} {"question": "Lunate sulcus is present in", "exp": "The occipital lobe sulciA. Transverse occipital B. Lateral occipital C. Lunate D. Superior and inferior polarReference: Chaurasia; 6th edition; 417 page", "cop": 4, "opa": "Frontal lobe", "opb": "Parietal lobe", "opc": "Temporal lobe", "opd": "Occipital lobe", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "09a7f48a-9ace-411e-a20a-d9c58bd2e3c0", "choice_type": "single"} {"question": "Order of neurovascular bundle in the femoral triangle from medial to lateral", "exp": "(B) Vein, Artery, Nerve # FEMORAL TRIANGLE: This is a clinically important triangular subfascial space in the superomedial one-third part of the thigh. It appears as a depression inferior to the inguinal ligament when the thigh is actively flexed at the hip joint. Its main contents are the femoral vessels and the femoral nerve.> Boundaries of the Femoral Triangle: Superiorly by the inguinal ligament. Medially by the medial border of the adductor longus muscle. Laterally by the medial border of the sartorius muscle. Muscular floor of the femoral triangle is not flat but gutter-shaped Formed from medial to lateral by the adductor longus, pectineus, and the iliopsoas. It is the juxtaposition of the iliopsoas and pectineus muscles that forms the deep gutter in the muscular floor. Roof of the femoral triangle is formed by the fascia lata, which includes the cribriform fascia.> Contents of the Femoral Triangle: This triangular space in the anterior aspect of the thigh contains Medial to Lateral: Vein-Artery-Nerve (VAN) the femoral Vein and its tributaries, the femoral Artery (femoral artery in femoral triangle) and its branches, the femoral Nerve and its branches, the lateral cutaneous nerve, the femoral branch of the genitofemoral nerve, lymphatic vessels, and some inguinal lymph nodes.", "cop": 2, "opa": "Nerve, artery, vein", "opb": "Vein, Artery, Nerve", "opc": "Artery, Vein, Nerve", "opd": "Nerve, Vein, Artery", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "9ebc4708-2e5d-43b0-8d6b-c6c65a11b097", "choice_type": "single"} {"question": "Major pa of intrinsic muscles of hand are innervated by", "exp": "Median nerve supplies abductor pollicis brevis, flexor pollicis brevis and opponens pollicis ( muscles of thenar eminence).Ulnar nerve supplies adductor pollicis, palmaris brevis, abductor digiti minimi, flexor digiti minimi, opponens digiti minimi, 4 lumbricals, 4 dorsal and 4 palmar interossei.Radial nerve doesn&;t supply any intrinsic muscle of hand.B D Chaurasia 7th edition Page no : 119", "cop": 1, "opa": "Ulnar Nerve", "opb": "Radial Nerve", "opc": "Median Nerve", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f7d1d06d-69fe-4299-9809-3357e1941578", "choice_type": "single"} {"question": "unconscious repletion of words said by the examiner", "exp": "clang, ====subsequent words will have rhyming seen in MANIA puns,=== double meaning words echolalia=== unconscious repletion of words said by the examiner, seen in catatonia Ref. Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg.No.194", "cop": 1, "opa": "echolalia", "opb": "echopraxia", "opc": "puns", "opd": "clang assosiation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f4bd5f6c-11ad-4799-9e49-b8d6e37d0ec6", "choice_type": "single"} {"question": "Familial amylodotic polyneuropathy is due to amyloidosis of nerves caused by deposition of", "exp": "Ref Robbins 9/e p259 Familial (Hereditary) Amyloidosis A variety of familial forms of amyloidosis have been described; most are rare and occur in limited geographic areas. The best-characterized is an autosomal recessive condition called familial Mediterranean fever. This is a febrile disorder characterized by attacks of fever ccompanied by inflammation of serosal surfaces, includ- ing peritoneum, pleura, and synol membrane. This dis- order is encountered largely in persons of Armenian, Sephardic Jewish, and Arabic origins. It is associated with widespread tissue involvement indistinguishable from reactive systemic amyloidosis. The amyloid fibril proteins are made up of AA proteins, suggesting that this form of amyloidosis is related to the recurrent bouts of inflamma- tion that characterize this disease. The gene for familial Mediterranean fever is called pyrin and encodes a protein that is a component of the inflammasome (Chapter 2). Patients have gain-of-function mutations in pyrin that result in constitutive overproduction of the pro- inflammatory cytokine IL-1 and persistent inflammation. In contrast with familial Mediterranean fever, a group of autosomal dominant familial disorders is characterized by deposition of amyloid predominantly in the peripheral and autonomic nerves. These familial amyloidotic poly- neuropathies have been described in kindreds in different pas of the world--for example, in Pougal, Japan, Sweden, and the United States. As mentioned previously, the fibrils in these familial polyneuropathies are made up of mutant forms of transthyretin (ATTRs).", "cop": 3, "opa": "Amyloid associated protein", "opb": "Mutant calcitonin", "opc": "Mutant transthyretin", "opd": "Normal transthyretin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fcda0aec-748c-4dd9-869a-ae11e12e274a", "choice_type": "single"} {"question": "Adolescents age stas at the age of", "exp": "Adolescence ranges from Early (10-13 yrs) Mid( 14-16yrs) Late(17-19 yrs) Ref: Ghai, 9th edition, Page- 60.", "cop": 2, "opa": "7 yrs", "opb": "10 yrs", "opc": "14 yrs", "opd": "17 yrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "72f0df7f-9403-41f2-a9da-8eb47e2ee9a5", "choice_type": "single"} {"question": "Normal length of CBD is", "exp": "Bile duct : Anatomy It lies in front of the poal vein and to the right of the hepatic aery Common hepatic duct is 1-4cm in length and has a diameter of approx. 4mm CBD is about 7-11 cm in length and 5-10 mm in diameter A fibroareolar tissue containing scant smooth muscle surround the mucosa (a distinct muscle layer is absent) Most impoant aeries to the Supra duodenal bile duct run parallel to the duct at the 3 & 9'o clock position Approximately 60% of the blood supply to the Supra duodenal bile duct originates inferiorly from the pancreaticoduodenal and retro duodenal aeries Whereas 38% of blood supply originate superiorly from the right hepatic atmeru and cystic duct aery Ref: Sabiston 20th edition Pgno : 1482-1484", "cop": 1, "opa": "7cm", "opb": "5cm", "opc": "3cm", "opd": "2cm", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ea11fbf4-39eb-462b-857a-44d3f0565d2e", "choice_type": "single"} {"question": "Osteogenic sarcoma arises from", "exp": "The tumor most commonly begins in the Metaphysis The most common site of involvement is Metaphysis of long bone around knee ***lower end of femur ***upper end of tibia Refer Maheshwari 4th/e p. 232", "cop": 2, "opa": "Epiphyses", "opb": "Metaphysis", "opc": "Growth plate", "opd": "Epiphyseal coex", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "5c3d93db-840c-4a7e-aa33-0574f41662a3", "choice_type": "single"} {"question": "In neurofibromatosis 1 most common tumor is", "exp": "Optic nerve glioma is an astrocytoma common in patients with neurofibromatosis 1. It is tumor of children most commonly seen in girls Refer khurana 6/e 419", "cop": 1, "opa": "Optic nerve glioma", "opb": "Cerebral astrocytoma", "opc": "Glioblastoma multiforme 8", "opd": "Meningioma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5bb20aea-050a-4b96-b076-23ef5e490319", "choice_type": "single"} {"question": "The coronary sinus", "exp": "Coronary Sinus is the largest vein of hea.it ends by opening to posterior of Right atrium. BD CHAURASIA'S HUMAN ANATOMY,VOL:1,6TH EDITION,PAGE NO:266", "cop": 2, "opa": "Lies in anterior pa of the coronary sulcus", "opb": "Ends in right atrium", "opc": "Has venae cordis minimae as its tributaries", "opd": "Develops from right anterior cardinal vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "1994895e-7e59-4469-bed6-ce69b80ba297", "choice_type": "single"} {"question": "Visual acuity used as cut off for school screening program is", "exp": "Initial screening done by school teachers", "cop": 2, "opa": "12-Jun", "opb": "9-Jun", "opc": "6-Jun", "opd": "18-Jun", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e8a79e2c-123a-4e99-9675-151d95c803bc", "choice_type": "single"} {"question": "Elastic cartilage seen in", "exp": null, "cop": 1, "opa": "Pinnae", "opb": "Articular Ends Of Bones", "opc": "Pubic Symphysis", "opd": "larynx", "subject_name": "Anatomy", "topic_name": null, "id": "69b1de45-805c-4f3c-84fe-90be1da95061", "choice_type": "single"} {"question": "A patient presented with weakness of the right side of the face with loss of pain and temperature , Pain and temperature sensation of the left leg is lost The lesion is most likely located", "exp": "RULE OF 4 weakness of face =palsy of facial muscles of=7th nerve affected =same side=7th NERVE from PONS Loss of pain, temperature from force = Trigeminal Nerve affected=Lesion in lateral side and ipsilateral Loss of pain , temperature in body = UL, LL=spinothalamic tract affected= Lesion in C/L side and also lateral side REF: BD CHAURASIA", "cop": 1, "opa": "lateral poms", "opb": "medial pons", "opc": "lateral medulla", "opd": "Medial medulla", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2050babe-cd91-4264-a15f-82b3ed4bcae0", "choice_type": "single"} {"question": "Screening method for medullary carcinoma thyroid is", "exp": "MCT can be of two types - sporadic and familial (occurring in MEN syn. 2A & 2B and Familial cases without MEN syn.) The familial MTC are more aggressive, multicentric (bilateral) and present at a younger age, therefore high risk cases should be screened for MTC by - detecting RET mutation. The genetic screening tests are supplemented by estimating serum calcitonin levels in the basal state and after stimulation by either calcium or pentagastrin. Prophylactic total thyroidectomy is indicated in RET mutation carriers once the mutation is confirmed. Ref : Bailey & love 25/e p797", "cop": 3, "opa": "S. alkaline phosphate", "opb": "S. calcium", "opc": "Serum calcitonin", "opd": "S. acid phosphatase", "subject_name": "Anatomy", "topic_name": null, "id": "ec086545-b354-4e25-807e-3a70e8c790da", "choice_type": "single"} {"question": "Gluteus medius is supplied by", "exp": "SUPERIOR GLUTEAL NERVE Root value: L4,L5,S1Course: enters the gluteal region through greater sciatic notch above pyriformis muscle. Runs between gluteus medius and gluteus minimus to end in tensor fascia lata. Branches :-it supplies 1. Gluteus medius 2. Gluteus minimus3. Tensor fascia lata {Reference: BDC 6E pg no. 173}", "cop": 1, "opa": "Superior gluteal nerve", "opb": "Inferior gluteal nerve", "opc": "Nerve to obturator intemus", "opd": "Nerve to quadratus femoris", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "7437167a-b933-4ca1-9730-d6f466bb6dd9", "choice_type": "single"} {"question": "Febrile response in CNS is mediated by", "exp": "ref Harrison 18/e 143p -145 Fever is produced in response to substance called pyrogens that acts by stimulating prostaglandins synthesis in vascular and periferal cells of hypothalamus.there are exogenous and endogenous pyogens", "cop": 1, "opa": "Bacterial toxin", "opb": "IL1", "opc": "IL6", "opd": "Interferon", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b41c17ed-a275-4203-aaa8-a4c73b33c48f", "choice_type": "single"} {"question": "Nerve associated with pharyngeal cleft is derived from", "exp": "Nerves of pharyngeal cleft - pretrematic nerve Eg: chorda tympani, tympanic branch of glossopharyngeal nerve. Ganglia are derived from neural crest cells Thus, nerves of pharyngeal clefts are derived from Neural crest cells.", "cop": 1, "opa": "Neural crest cells", "opb": "Mesoderm", "opc": "Neural plate ectoderm", "opd": "Notochord", "subject_name": "Anatomy", "topic_name": "General Embryology 2", "id": "7c8d3cc5-6048-47c4-a8ba-2eef28d56ba4", "choice_type": "single"} {"question": "Keratometer is used to assess.", "exp": "It is an objective method. Keratometer is used for: Estimate corneal astigmatism Measure the curvature of the cornea Calculate the power of intraocular lens (IOL) Image: Keratometer", "cop": 1, "opa": "Curvature of cornea", "opb": "Diameter of cornea", "opc": "Thickness of cornea", "opd": "Curvature of lens", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "f8890bd9-54ed-408f-b94f-7225307d3f68", "choice_type": "single"} {"question": "Calcific hepatic metastasis are seen in", "exp": "Calcified hepatic metastases Clacified hepatic metastases are most frequently associated with mucin-producing neoplasm such as colon carcinoma or less likely ovarian carcinoma", "cop": 1, "opa": "Adenocarcinoma of the colon", "opb": "Carcinoid tumors", "opc": "Renal cell carcinoma", "opd": "Lymphoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b7317867-92f2-4ae1-bab7-23b87fec96bc", "choice_type": "single"} {"question": "Surgeon excises a poion of liver to the left of the attachment of the falciform ligament. The segments that have been resected are", "exp": "Falciform ligament Falciform ligament is the most obvious external landmark on the liver surface Plane passing through the falciform ligament passes through the left lobe It divides the left lobe into a medial segment (Segment IV) and lateral segment (Segment II and III) Ref: Sabiston 20th edition Pgno : 1421", "cop": 3, "opa": "Segment 1a and 4", "opb": "Segment 1 and 4b", "opc": "Segment 2 and 3", "opd": "Segment 1 and 3", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "81482ac4-0f5a-4e5b-8da1-b8981779c6b5", "choice_type": "single"} {"question": "Contents of anatomical snuff box are\n(A)Radial Artery\n(B)Tendon of Abductor Poilicis longus\n(C)Tendon of extensor poilicis brevis\n(D)Scaphoid bone\n(E)Superficial cutaneous branch of radial nerve", "exp": "Anatomical Snuff Box - BDC4th/ Vol. 1130\n♦ It is a triangular depression in lateral side of wrist seen best when thumb is extended\n♦ Boundaries\n● Anterior - Tendon of abductor Pollicis lonus Tendon of extensor Pollicis brevis\n● Posterior - Tendon of extensor pollids iongus\n● Above\n♦ Styloid process of radius\n♦ Floor – ScaphoidQ & trapezium bone\n♦ Crossed by radial A Anatomical Snuff Box – snell’s 8th/533-35\n♦ It is a depression in the skin that lies distal to styloid process of radius.\n♦ Boundaries\n● Medial\n● Tendon of Extensor pollicis longus\n● Lateral\n● Tendon of abductor pollicis longus\n● Tendon of Extensor pollicis brevis\n♦ Floor\n● Proximally-styloid process of radius\n● Distally-base of rst metacarpal bone of thumb\n♦ B/w these bones , beneath the oor lies the scaphoid & the trapezium (felt but not identiable)\n♦ Radial Artery - Can be palpated\n♦ Cephalic vein - Can also someti mes be recognised crossing the box as it ascends the forearm Mnemonics Floor -\nFiRST Fi- First Metacarpal bone R- Radial Styloid S-Scaphoid bone T- Trapezium Contents - VAN V- Cephalic vein A - Radial artery N - Radial Nerve (cutaneous Branch)\nClinical signicance of anatomical snuff box:\n• The pulsations of radial artery can be felt in the anatomical box.\n• The tenderness in the anatomical box indicates fracture of scaphoid bone.\n• The cephalic vein at this site is often used for giving intravenous uids.\n• The supercial branches of the radial nerve can be rolled over the tendon of extensor pollicis longus.\nAnatomical Snuff Box Anatomical Snuffbox is a triangular depression on the lateral aspect of wrist immediately distal to the radial styloid process,\nthat becomes prominent when thumb is fully extended Boundaries Floor Contents Lateral /Anterior wall\n● Abductor Pollicis longus (Radially)\n● Extensor Pollicis Brevis (Medially') Medial /Posterior wall\n● Extensor Pollicis\n● Radial styloid\n● Scaphoid (smooth convex articular surface)\n● Trapezium\n● Base of First Metacarpal\n● Cephalic vein\n● Radial artery\n● Supercial radial nerve", "cop": 1, "opa": "AE", "opb": "BC", "opc": "BA", "opd": "DE", "subject_name": "Anatomy", "topic_name": null, "id": "bfe97917-4de8-4cff-9046-6fd196a268a9", "choice_type": "single"} {"question": "Hypoxic hypoxia is seen in", "exp": "Type of hypoxia Features Examples Hypoxic hypoxia Occur when enough oxygen is not present in the air / when decreasing atmospheric pressure prevents diffusion of oxygen from lungs to blood stream High altitudes COPD AV shunt etc Anemic hypoxia Haemoglobin available to carry oxygen is reduced Anemia Non-functional Hb - Co poisoning; Met-Hb etc Stagnant hypoxia Decreased/ sluggish blood flow to tissues resulting in inadequate oxygen supply Ischemia/ congestion Histotoxic hypoxia Oxygen delivered to tissues is normal but tissues can't utilize oxygen. Cyanide poisoning", "cop": 4, "opa": "CO poisoning", "opb": "HCN poisoning", "opc": "Ischemia", "opd": "AV shunt", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "57709afb-d54d-4954-ae7b-be9bbdbf32a2", "choice_type": "single"} {"question": "The most unlikely feature Iof HCC is", "exp": "Clinical features of HCC Most common symptom is abdominal pain >weight Significant weight loss : <5% in 1 month or 10% in 6 months or 20% in 1 year Usually presents at late stage, symptoms at advanced stage are vague Non-specific symptoms( anorexia, weight loss) and hepatomegaly Paraneoplastic syndromes in HCC - Hypercholestrolemia( most common), hypoglycemia, erythrocytosis, hypercalcemia Vascular bruit (25%), GI bleed (10%), tumor rupture (2-5%), jaundice due to biliary obstruction (10%), Paraneoplastic syndromes (<5%) Ref: Sabiston 20th edition Pgno :1458-1463", "cop": 4, "opa": "Hepatomegaly", "opb": "Raised AFP levels", "opc": "Raised alkaline phosphatase", "opd": "Jaundice", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1b8fe7b7-26f4-4cbf-a109-121ecb9fc91e", "choice_type": "single"} {"question": "Renal transplantation is preferred in", "exp": "Renal transplantation is the preferred treatment for many patients with end stage renal disease (ESRD), because it provides a better quality of life for them than dialysis. The most common causes of ESRD (in decreasing order) are: Diabetes mellitus Hypeension Glomerulonephritis Ref : Cambell's Urology 8/e p346", "cop": 3, "opa": "Bilateral staghorn calculus", "opb": "Bilateral hydronephrosis", "opc": "Chronic glomerulonephritis", "opd": "AKI", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "befa0e9e-aa25-47ac-87dd-f2d6e283b27c", "choice_type": "single"} {"question": "Common bile duct injuries are most commonly seen in", "exp": "Bile duct injury and ligation Most benign strictures follow iatrogenic bile duct injury. Most commonly during laparoscopic cholecystectomy Incidence of bile duct injury during open cholecystectomy is 0.1-0.2 % Incidence of bile duct injury during laparoscopic cholecystectomy is 0.3-0.85 % Ref :Sabiston 20th edition Pgno :1502", "cop": 4, "opa": "Radical gastrectomy", "opb": "Penetrating injuries of abdomen", "opc": "ERCP and sphincterectomy", "opd": "Laparoscopic cholecystectomy operation", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "712e7578-fa82-44ea-ab18-eb756d79e47a", "choice_type": "single"} {"question": "The most common organism causing osteomyelitis is", "exp": "The most common organism in osteomyelitis in intravenous drug users is staphylococcus aureus. Pseudomonas aeruoginosa an otherwise unusual cause of osteomyelitis, is the second most frequently observed microorganism Refer Maheshwari 6th/e p 168", "cop": 4, "opa": "E, coli", "opb": "Pseudomonas", "opc": "Klebsiella", "opd": "Staph aureus", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "62e7b0bd-7cfe-4074-b6f7-88c9d6732ab8", "choice_type": "single"} {"question": "Growth plate of a long bone is supplied by", "exp": "Epiphyseal artery supplies Epiphysis and Growth plate.", "cop": 3, "opa": "Metaphyseal artery", "opb": "Nutrient artery", "opc": "Epiphyseal artery", "opd": "Periosteal artery", "subject_name": "Anatomy", "topic_name": null, "id": "b76e7390-96b9-4f11-873c-a5b640ed05e4", "choice_type": "single"} {"question": "Common occular manifestation of chromosomes 13 is", "exp": "Trisomy 13 is called pataue syndrome. And is characterized by micropthalmous cataract,corneal opacity and retinal dysplasia Refer khurana 6/e", "cop": 2, "opa": "Capillary hemangioma", "opb": "Bilateral microopthalmous", "opc": "Neurofibroma", "opd": "Dermoid cyst", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "739c6be5-933a-48db-9af4-e356e83ef3fc", "choice_type": "single"} {"question": "In inflammatory process ,the prostaglandins E1and E2 cause", "exp": "Ref Robbins 9/e p85 It is a direct vasodilator, relaxing smooth muscles, and it inhibits the release of noradrenaline from sympathetic nerve terminals. It does not inhibit platelet aggregation, where PGI2 does. PGE2 also suppresses T cell receptor signaling and may play a role in resolution of inflammation. Up-regulation of PGE2 has been implicated as a possible cause of nail clubbing. Fuhermore, its postpaal synthesis in newborns is considered as one cause of patent ductus aeriosus", "cop": 1, "opa": "Vasodilation", "opb": "Increased gastric output", "opc": "Decreased body temperature", "opd": "Vaso constriction", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9e260f00-0b2b-4c22-9f38-042ea75c6c68", "choice_type": "single"} {"question": "The best investigation for diagnosing Best disease is", "exp": "Best diseaseAutosomal dominant inheritance due to mutation of bestrophin gene on 11q13 chromosomeLipofuscin accumulation throughout the RPELarge yellow yolk like ( vitelliform ) lesion - EGG YOLK APPEARANCEBest investigation for diagnosis of Best disease is made on the basis of abnormal electrooculogram findings - a severe loss of light response of the standing potential occursArden ratio - less than 1.5 & frequently near 1.1Electro-retinography - reduced C waveBEST disease - relatively normal electroretinographic results with abnormal electro oculographic findings(Refer: AH Khurana, Comprehensive Textbook of Ophthalmology,5thedition, pg no: 520-521)", "cop": 3, "opa": "EEG", "opb": "Electroneurogram", "opc": "Electrooculogram", "opd": "Electroretinogram", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0ba02894-9278-4304-8de0-fd61b610db69", "choice_type": "single"} {"question": "Koch's triangle has blood supply from", "exp": "Koch&;s triangle has blood supply from Right coronary", "cop": 1, "opa": "Right coronary", "opb": "Left circumflex", "opc": "Left anterior descending", "opd": "Anterior aoic sinus", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "3e34ba5d-4bbd-44af-b5c5-d5d6cbbd38af", "choice_type": "single"} {"question": "cove sensitization is used for", "exp": "In cove sensitization also called as imagined punishment, the individual who wants to quit alcohol will be asked to think about adverse consequences of taking alcohol like getting arrested for drunken driving or facing a accident underintoxicated state. He would be told to dream as if if he is drunk and lies intoxicated in the road and has to be brought back to the home by family members where he will be given lot of advice from neighbours and there would be a loss of respect. While these imagined exposure the patient feels bad and makes sure thet he should quit alcohol and his thoughts ahgainst alcohol increases. Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 845", "cop": 4, "opa": "PTSD", "opb": "hysteria", "opc": "brain injury", "opd": "alcohol use", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "7b535d72-590a-462c-881c-0898755b9b45", "choice_type": "single"} {"question": "Rosenthal's syndrome is due to deficiency of", "exp": "Hemophilia C(Rosenthal syndrome) It is due to deficiency of factor XI Ref: http://en.wikipedia.org/wiki/Hemophilia_C", "cop": 1, "opa": "XI", "opb": "VIII", "opc": "XII", "opd": "IX", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bbf59dc3-f75f-411b-9b24-fb5fc19c47df", "choice_type": "single"} {"question": "Ligation of the common hepatic aery will compromise blood flow in", "exp": "Rt. Gastric aeryarises from common hepatic aery andRt. Gastroepiploic aeryarises fromgastroduodenal aerywhich is a branch of common hepatic aery. Therefore,ligation of common hepatic aerywill lead to impaired blood supply inRt. Gastric aeryandRt. Gastroepiploic aery. Left gastric aery arises from CT. Sho gastric aeries arise from splenic aery.", "cop": 4, "opa": "Right and Left gastric aery", "opb": "Right gastric and sho gastric aeries", "opc": "Right gastroepiploic and sho gastric aeries", "opd": "Right gastric and right gastroepiploic aery", "subject_name": "Anatomy", "topic_name": "NEET Jan 2020", "id": "367f2590-d02c-400d-a24e-62f07f9c3a83", "choice_type": "single"} {"question": "Anterosuperior sternal pa of hea is made up of", "exp": "Surfaces Anterior (or sternocostal) - Right ventricle. Posterior (or base) - Left atrium Inferior (or diaphragmatic) - Left and right ventricles. Right pulmonary - Right atrium. Left pulmonary - Left ventricle. Borders Right border - Right atrium Inferior border - Left ventricle and right ventricle Left border - Left ventricle (and some of the left atrium) Superior border - Right and left atrium and the great vessels Apex : Left ventricle", "cop": 4, "opa": "Right atrium and auricle", "opb": "Left atrium", "opc": "Left ventricle", "opd": "Right ventricle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "e0b06c7d-642a-486d-9f79-9023e6c1d4f4", "choice_type": "single"} {"question": "Horizontal semicircular canal is", "exp": "D i.e Lateral", "cop": 4, "opa": "Anterior", "opb": "Superior", "opc": "Posterior", "opd": "Lateral", "subject_name": "Anatomy", "topic_name": null, "id": "a997ceac-936d-419d-9e06-e45a46844480", "choice_type": "single"} {"question": "The maximum period of imprisonment a metropolitan magistrate can give is", "exp": "Power of magistrates Magistrate period of imprisonment amount of fine Chief Judicial Magistrate/ Chief metropolitan Magistrate upto7 yerars unlimited Judicial 1st class magistrate/ Metropolitan magistrate upto 3 years Rs 10,000/- Judicial 2nd class magistrate upto 1 year Rs 5000/- Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 9", "cop": 2, "opa": "1 year", "opb": "3 year", "opc": "5 year", "opd": "7 year", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f9f90c17-7894-4bff-9d27-9a44e6f7ec35", "choice_type": "single"} {"question": "Shoest pa of the colon is", "exp": "The large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, the ileocaecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then descending to the rectum and its endpoint at the anal canal. Overall, in humans, the large intestine is about 1.5 meters (5 ft) long, which is about one-fifth of the whole length of the gastrointestinal tract. Ref - BDC 6e vol2 pg271-273", "cop": 1, "opa": "Ascending colon", "opb": "Descending colon", "opc": "Transverse colon", "opd": "Sigmoid colon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e9666686-c4a7-4400-a829-1ffc3e12ebf9", "choice_type": "single"} {"question": "The most impoant function of epitheliod cells in TB is", "exp": "ref harsh Mohan 9/e p97 The granuloma contains mostly blood-derived macrophages,epithelioid cells (differentiated macrophages) and multinucleated giant cells (also known as Langhans giant cells), surrounded by T lymphocytes . Caseous granulomas are typical oftuberculosis. ... T cells were then rapidly recruited to the forming granuloma. Epithelioid cells are cells of the mononuclear phagocyte system found in ceain granulomas mainly associated with intense immunological activity. ... It is suggested that \"vesicular epithelioid cellscould develop from \"secretory\" epithelioid cells by a process of degeneration.", "cop": 2, "opa": "Phagocytosis", "opb": "Secretory", "opc": "Antigenic", "opd": "Healing", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3badf54a-d51b-47d3-8bb6-47f2e7fdb141", "choice_type": "single"} {"question": "Gas used in laproscopy is", "exp": "Ref:Bailey and love 27th edition Pg no :105", "cop": 1, "opa": "Carbon dioxide", "opb": "Sulphur dioxide", "opc": "Nitrogen", "opd": "Oxygen", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "faab13b6-b64c-43c7-8bce-58ccceaead57", "choice_type": "single"} {"question": "To stop variceal bleeding pressure in sengstaken Blakemore tube should be", "exp": "Sengstaken - Blakemore tube If the rate of blood loss prohibits endoscopic evaluation, a sengstaken-Blakemore tube may be inseed to provide temporary hemostasis Once inseed, the gastric balloon is inflated with 300ml of air and retracted to the gastric fundus, where the varices at the esophagogastric junction are tamponade by the subsequent inflation of the esophageal balloon to a pressure of 40mmHg The remaining two channels allow gastric and esophageal aspiration A radiograph is used to confirm the position of the tube The balloons should be temporarily defalated after 12 hrs to prevent pressure necrosis of the esophagus Ref: Bailey and love 27th edition Pgno : 1164", "cop": 1, "opa": "40mmHg", "opb": "50mmHg", "opc": "60mmHg", "opd": "70mmHg", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "952c4afb-852c-45dc-9e7f-90bfea6b71fb", "choice_type": "single"} {"question": "Sho gastric aery is a branch of", "exp": "Sho gastric aery is a branch of the splenic aery. Splenic aery gives it branches to branches to pancreas, sho gastric aery, left gastroepiploic and posterior gastric. right gastroepiploic is not its branch. ref - BDC 6e vol2 pg277", "cop": 1, "opa": "Splenic aery", "opb": "Left gastroduodenal aery", "opc": "Left gastroepiploic aery", "opd": "Poal vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "8660bd65-e5f1-49af-a92e-5870769389a6", "choice_type": "single"} {"question": "Mobile bone of skull", "exp": "The mandible or lower jaw is the largest and the strongest bone of the face. It develops from the first pharyngeal arch. It has a horseshoe-shaped body which lodges the teeth, and pair of rami which project upwards from posterior ends of the body. The rami provide attachment to the muscles of mastication. Ref BDC volume 3,sixth edition pg 31", "cop": 2, "opa": "Maxilla", "opb": "Mandible", "opc": "Ethmoid", "opd": "Sphenoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b51bbd29-4082-416c-8d90-28b9ff730b1e", "choice_type": "single"} {"question": "Enophthalmus is due to palsy of", "exp": "Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition. Enophthalmos (i.e. retraction of the eyeball); is possibly caused by paralysis of the smooth (orbitalis) muscle in the floor of the orbit.", "cop": 3, "opa": "Levator palpebrae superioris", "opb": "Superior tarsal muscle", "opc": "Orbital muscle", "opd": "Inferior tarsal muscle", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "995e76ff-ecf5-4631-bf34-02bbcc74e795", "choice_type": "single"} {"question": "Diagnosis of myasthenia gravis is done by using", "exp": "(Ref: KDT 6/e p104) Myasthenia gravis can be differentiated from cholinergic crisis with the help ot a sho acting anticholinesterase agent, edrophonium. It improves the symptoms in mvasthenia gravis whereas worsens the condition in cases of cholinergic crisis. Neostigmine is used for the treatmet of myasthenia.", "cop": 1, "opa": "Edrophonium", "opb": "Neostigmine", "opc": "Succinylcholine", "opd": "Atropine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "97b767b5-e9b8-4628-b751-f0684e6fdfa4", "choice_type": "single"} {"question": "Blood supply of femoral head is", "exp": "BLOOD SUPPLY OF FEMORAL HEAD:- The head of femur is paly supplied by a branch of obturator aery along the ligamentum teres.Main aerial supply is from retinacular aeries, branch of medial circumflex femoral aery.These aeries get injured in intracapsular fracture neck of femur, leading to avascular necrosis of the head. In such cases hip joint need to be replaced. {Reference: BDC 6E pg no.19}", "cop": 2, "opa": "Femoral aery", "opb": "Obturator aery", "opc": "Internal pudendal aery", "opd": "Lateral circumflex aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "9549b68e-7862-4e66-ab58-6127a02ee375", "choice_type": "single"} {"question": "Amotivation syndrome caused by", "exp": "Psychiatric presentation---------------------Mimics panic attacks Patient on intoxication has increased activation of sympathetic nervous system Gate way drug This drug is called gate way drug as when a person uses this drug, he has a chance of increased exposure to other drugs Amotivation syndrome Patient with amotivation syndrome will lack of drive, abulia, no motivation for any activities hemp insanity insanity caused by cannabis is called hemp insanity if a person with family history of psychosis takes cannabis there is a chance a kindling of psychotic symptoms Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no.645", "cop": 1, "opa": "Cannabis abuse", "opb": "Opioid abuse", "opc": "Alcohol abuse", "opd": "Heroin abuse", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "d72bf4e5-7f81-49c3-98c7-eeebbf960013", "choice_type": "single"} {"question": "Neural tube formation occurs on", "exp": null, "cop": 1, "opa": "18 to 23 days post fertilization and is the second stage of craniofacial development", "opb": "28 to 38 days post fertilization and is the third stage of craniofacial development", "opc": "42 to 55 days post fertilization and is the fourth stage of craniofacial development", "opd": "17th day post fertilization and is the first stage of craniofacial development", "subject_name": "Anatomy", "topic_name": null, "id": "1cad68e2-84bb-4bec-8b1f-f8a8372d7bf8", "choice_type": "single"} {"question": "General Paresis of insane is associated with", "exp": "It is a late complication of neurosyphilis", "cop": 2, "opa": "Miliary tuberculosis", "opb": "Teiary Syphilis", "opc": "Vitamin B12 deficiency", "opd": "Autoimmune encephalitis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0e0f7680-af15-459c-b640-366004e3f92e", "choice_type": "single"} {"question": "Corneal stroma is derived from", "exp": "The corneal stroma is a mesenchymal tissue, derived from the periocular neural crest, is the thickest layer of the cornea, and is 'sandwiched' between the epithelium and the inner endothelium. The stroma is composed of organized collagen, mainly type I and type V collagen fibers, which maintain transparency. Keratocytes (fibroblasts) are located between the lamella collagen fibers and secrete an extracellular matrix, which includes collagen and proteoglycans, and also produce crystalline proteins to maintain corneal transparency. Ref - Pubmed.com", "cop": 3, "opa": "Paraxial mesoderm", "opb": "Intermediate mesoderm", "opc": "Neural crest", "opd": "Ectoderm", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "e68ee52b-106b-4249-9afe-d4469a70fdcd", "choice_type": "single"} {"question": "Dorsum of first webspace is supplied by nerve", "exp": "Nerve supply to lower limb Thigh: Anterior compament - femoral nerve Medial compament - obturator nerve Posterior compament - tibial nerve (Sciatic nerve) Leg: Anterior - Deep Peroneal Nerve (DPN) Lateral - Superficial peroneal nerve (SPN) Posterior- Tibial nerve Foot: Dorsum of foot (except first web space)- superficial peroneal nerve Dorsum of first web space - Deep peroneal nerve (DPN) Plantar surface - Medial and lateral plantar nerve (terminal division of tibial nerve) Middle malleolus - Saphenous nerve (branch of femoral nerve) Lateral margin - Sural nerve", "cop": 2, "opa": "Superficial peroneal", "opb": "Deep peroneal", "opc": "Sural", "opd": "Posterior tibial", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "81bbf1f4-3d12-43c2-89b6-dbd5a3f58864", "choice_type": "single"} {"question": "Level of hyoid bone is at", "exp": "Vertebral level of various structures in the neck:\nHyoid bone - C3\nUpper border and notch of thyroid cartilage - C3/C4\nThyroid cartilage - C4-05\nCricoid cartilage - C6\nSuprasternal notch - T2/T3", "cop": 1, "opa": "C3", "opb": "C4", "opc": "C5", "opd": "C7", "subject_name": "Anatomy", "topic_name": null, "id": "f1f1d002-5191-4f04-9d75-c6557a54b164", "choice_type": "single"} {"question": "The superficial external pudendal aery is a branch of", "exp": "The femoral aery in the femoral triangle gives off 3 superficial branches :superficial epigastric aery,superficial external pudendal andsuperficial circumflex iliac aery.Reference: Textbook of anatomy, Abdomen and Lower limb, Vishram Singh, 2nd edition, page no.341", "cop": 1, "opa": "Femoral aery", "opb": "External iliac aery", "opc": "Internal iliac aery", "opd": "Aoa", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "5fea837a-5fb5-4543-9fb2-e1427e5310fc", "choice_type": "single"} {"question": "Middle piece of sperm tail made up of", "exp": "Pa of axial filament which lies in middle piece is surrounded a spiral sheath made up of mitochondria Human embryology Tenth edition Pg no19", "cop": 3, "opa": "Golgibody", "opb": "Centriole", "opc": "Mitochondria", "opd": "Lysosome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "166154d6-69a8-45b0-a35d-2857148ba7e1", "choice_type": "single"} {"question": "Posterior dislocation of the femur on the tibia is prevented by", "exp": "CRUCIATE LIGAMENTS: Very thick and strong fibrous bands.Direct bonds of union between tibia and fibula.Maintain anteroposterior stability of knee joint. Anterior cruciate ligament:- Begins from anterior pa of intercondylar area of tibia, runs upward, backward and laterally and is attached to the posterior pa of medial surface of lateral condyle of femur. Taut during extension of knee. The anterior cruciate ligament is more commonly damaged than the posterior.It may be injured in violent hyperextension of knee or anterior dislocation of tibia. Posterior cruciate ligament:- Begins from posterior pa of intercondylar area of tibia, runs upwards, forwards and medially and is attached to lateral surface of medial condyle of femur. Taut during flexion of knee. The posterior cruciate ligament is injured in posterior dislocation of tibia. It prevents posterior dislocation of femur on tibia. Both these are supplied by middle genicular nerves and vessels. {Reference: BDC 9 E}", "cop": 2, "opa": "Anterior cruciate ligament", "opb": "Posterior cruciate ligament", "opc": "Medial collateral ligament", "opd": "Lateral collateral ligament", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "be5edcf2-a3cf-440b-96e4-e8575d3c4fae", "choice_type": "single"} {"question": "Tensile strength of wound aftr laparoscopic cholecystectomy in a 30yr old woman depends upon", "exp": "ref Robbins, 8/e p105 -106 Collagen is a ubiquitous protein with remarkable mechanical propeies. It is highly elastic, shows large during tropocollagen. The molecular component of a collagen fibril, consisting of three polypeptide chains coiled around each other.", "cop": 2, "opa": "Replacement of type 3collagen", "opb": "Extensive cross linking of tropocollagen", "opc": "Macrophage activity", "opd": "Granulation tissue", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fc9436c8-16a9-4a45-8e50-5e86dfd4b188", "choice_type": "single"} {"question": "The optic nerve terminates in the", "exp": null, "cop": 4, "opa": "Thalamus", "opb": "Pituitary gland", "opc": "Medulla Oblongata", "opd": "Lateral Geniculate Body", "subject_name": "Anatomy", "topic_name": null, "id": "ee29c25e-3a88-4c73-afe0-74f28f06e792", "choice_type": "single"} {"question": "Extent of esophagus is", "exp": "The esophagus has cervical, thoracic, and abdominal pas, extending from the lower end of the pharynx (C6 veebrae) to the cardiac opening of the stomach (T11 or 12 veebral level). It is about 25 to 30 cm long", "cop": 2, "opa": "C3 - C6", "opb": "C6 - T11", "opc": "T10 - T12", "opd": "C3 - T6", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "0c67fd53-5b37-43aa-920a-fe01ce1a348a", "choice_type": "single"} {"question": "russels sign is assosiated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 2, "opa": "anorexia nervosa", "opb": "bulimia nervosa", "opc": "obesity", "opd": "metabolic syndrome", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "1a10a550-8a18-4664-808b-c3b687369f49", "choice_type": "single"} {"question": "Cranial pa of accessory nerve supplies", "exp": "Sternocleidomastoid and trapezius develop from branchial arch mesoderm and are supplied by spinal pa of the accessory nerve. Levator scapulae are supplied by a branch from dorsal scapular nerve and branches from C3, C4. BD Chaurasia 7th edition Page no: 65", "cop": 1, "opa": "Sternocleidomastoid", "opb": "Trapezius", "opc": "Levator scapulae", "opd": "Levator palatini", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "9b424535-eb42-4c23-a467-7a50cf60c294", "choice_type": "single"} {"question": "SAG M stands for", "exp": "SAG-M solution - Packed red cells are stored to increase shelf life to 5 weeks at 2-6degC SAG-M : is Saline-Adenine-Glucose-Mannitol Ref: Bailey and love 27th edition Pgno :21", "cop": 2, "opa": "Sodium chloride , Adenine , Glucose anhydrate , Mannitol", "opb": "Sodium citrate , Adenine , Glucose anhydrate , Mannitol", "opc": "Sodium citrate , Adenosine , Glucose anhydrate , Mannitol", "opd": "Sodium chloride , Adenine , Gelatin , Mannitol", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4f70a69f-4732-4964-933e-379b502b72a8", "choice_type": "single"} {"question": "Inversion / Eversion movements occurs at", "exp": "(Subtalar joints) (154- BDC-2 4th edition)* Inversion and Eversion of foot occurs at - Subtalar (Talocalcaneum) & Talocalcaneonavicular joints* Principal muscles involved in Inversion are - Tibialis anterior, Tibialis posterior* Principal muscles involved in Eversion are Peroneus longus, Peroneus brevis* Pronation and Supination of the foot - takes place chiefly at the Transverse tarsal joints** and partly at smaller intertarsal, tarsometatarsal and inter metatarsal joints", "cop": 2, "opa": "Ankle joints", "opb": "Subtalar joints", "opc": "Tibiotalar joints", "opd": "Transverse tarsal joints", "subject_name": "Anatomy", "topic_name": "Lower Extremity", "id": "b368c994-1786-4e65-84e4-9979b9899ee0", "choice_type": "single"} {"question": "Occupational lung disease commonly seen in Textile industry workers is", "exp": "Workers occupationally exposed to cotton dust (but also to flax, hemp, or jute dust) in the production of yarns for textiles and rope making are at risk for an asthma-like syndrome known as byssinosis. Ref Harrison 19th edition pg 1688", "cop": 1, "opa": "Byssinosis", "opb": "Bagassosis", "opc": "Farmers lung", "opd": "Asbestosis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "2ac4095e-b973-494e-b886-1b0ae79176d3", "choice_type": "single"} {"question": "Hyoid lies at the level of", "exp": "Hyoid is a U-shaped bone situated in the anterior midline of the neck between the chin and the thyroid cailage.At rest,it lies at the level of the third cervical veebra behind and the base of the mandible in front. REF,BDC VOL.3,FIFTH EDITION", "cop": 1, "opa": "C3", "opb": "C5", "opc": "C7", "opd": "T2", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "fe2ad6bf-2ce4-4e32-86cf-f44ddc329d1f", "choice_type": "single"} {"question": "Large and most impoant branch of the posterior tibial aery is", "exp": "Peroneal aery is the largest branch of the posterior tibial aery. It supplies the posterior and lateral compaments of the legOther branches of the posterior tibial aery are:circumflex fibular aerymedial plantar aerylateral plantar aeryRef: Vishram Singh; Volume II; 2nd edition; Page no: 416", "cop": 2, "opa": "Circumflex fibular aery", "opb": "Peroneal aery", "opc": "Medial plantar aery", "opd": "Lateral plantar aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "dc37a7de-b62d-4bd7-ac82-59d608feae72", "choice_type": "single"} {"question": "Internal organs in the fetus develop at", "exp": "D i.e. 6 weeks The embryonic period or period of organogenesis occurs from 3rd- weeksQ (Langman's) /4th- 801 weeksQ (Persuad) Although the critical development events occur during first three weeks, such as cleavage of the zygote, blastogenesis & early development of the nervous & cardiovascular systems. All major external & internal structures are established during 4- 8 weeks.", "cop": 4, "opa": "24 weeks", "opb": "12 weeks", "opc": "10 weeks", "opd": "6 weeks", "subject_name": "Anatomy", "topic_name": null, "id": "cf222359-5bf6-4479-bb59-51899e0d94fa", "choice_type": "single"} {"question": "Loss of Direct and consensual light reflex Is due to\nlesion of", "exp": null, "cop": 2, "opa": "Trigeminal nerve", "opb": "Occulomotor nerve", "opc": "Trochlear nerve", "opd": "Abducens nerve", "subject_name": "Anatomy", "topic_name": null, "id": "001548c5-7326-4c68-97dd-6aeb121327ab", "choice_type": "single"} {"question": "Cavity of mesencephalon", "exp": "The cavity of mesencephalon forms the cerebral aqueduct.The cavity of Rhombencephalon forms the fouh ventricle.The cavity of prosencephalon forms lateral and third ventricle.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 4)", "cop": 3, "opa": "Lateral ventricle", "opb": "Fouh ventricle", "opc": "Cerebral acqueduct", "opd": "Third ventricle", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "8e23121f-ed9e-407d-80f5-eed6c35970c1", "choice_type": "single"} {"question": "The most common cause of preventable hospital death is", "exp": "PE is the most common preventable cause of death among hospitalized patients. Clinical features The diagnosis of pulmonary embolism (PE) may be aided by asking three questions: * Is the clinical presentation consistent with PE? * Does the patient have risk factors for PE? * Are there any alternative diagnoses that can explain the patient's presentation? Clinical presentation varies, depending on number, size and distribution of emboli and on underlying cardiorespiratory reserve (Box 17.83). A recognised risk factor is present in 80-90% (see Box 23.65, p. 975). The presence of one or more risk factors increases the risk fuher still. Ref Davidson edition23rd pg 619", "cop": 1, "opa": "Acute pulmonary embolism", "opb": "Hea failure", "opc": "Myocardial infraction", "opd": "Cancer", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "663db463-a35d-4e8a-8080-482f20dfd540", "choice_type": "single"} {"question": "The main danger with low tension alternating current is", "exp": "The main danger with alternative current injuries is from alternating current interactions with normal cardiac pacing It can cause cardiac arrest. The electricity itself doesn't usually cause significant underlying myocardial damage. So resuscitation if successful should be lasting. Ref: Bailey and love 27th edition Pg no : 631", "cop": 2, "opa": "Myoglobinuria", "opb": "Cardiac arrest", "opc": "Renal failures", "opd": "Burns", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "41004212-8bad-4a97-a35d-0b38d239efb7", "choice_type": "single"} {"question": "Ram Devi presented with generalized edema sweating and flushing tachycardia and fever after bee sting .this is", "exp": "Ref Robbins 9/e p202 Immediate (Type I) Hypersensitivity Immediate hypersensitivity is a tissue reaction that occurs rapidly (typically within minutes) after the interaction of antigen with IgE antibody that is bound to the surface of mast cells in a sensitized host. The reaction is initiated by entry of an antigen, which is called an allergen because it triggers allergy. Many allergens are environmental substances that are harmless for most persons on exposure. Some people apparently inherit genes that make them susceptible to allergies. This susceptibility is manifested by the propen- sity of such persons to mount strong TH2 responses and, subsequently, to produce IgE antibody against the aller- gens. The IgE is central to the activation of the mast cells and release of mediators that are responsible for the clinical and pathologic manifestations of the reaction. Immediate hypersensitivity may occur as a local reaction that is merely annoying (e.g., seasonal rhinitis, or hay fever), severely debilitating (asthma), or even fatal (anaphylaxis). Sequence of Events in Immediate Hypersensitivity Reactions Most hypersensitivity reactions follow the same sequence of cellular responses (Fig. 4-7): * Activation of TH2 cells and production of IgE antibody. Aller- gens may be introduced by inhalation, ingestion, or injection. Variables that probably contribute to the strong TH2 responses to allergens include the route of entry, dose, and chronicity of antigen exposure, and the genetic makeup of the host. It is not clear if allergenic substances also have unique structural propeies that endow them with the ability to elicit TH2 responses. Immediate hypersensitivity is the prototypical TH2-mediated reaction. The TH2 cells that are induced secrete several cytokines, including IL-4, IL-5, and IL-13, which are responsible for essentially all the reactions of immediate hypersensitivity. IL-4 stimulates B cells specific for the allergen to undergo heavy-chain class switching to IgE and to secrete this immunoglobulin isotype. IL-5 acti- vates eosinophils that are recruited to the reaction, and IL-13 acts on epithelial cells and stimulates mucus secre- tion. TH2 cells often are recruited to the site of allergic reactions in response to chemokines that are produced locally; among these chemokines is eotaxin, which also recruits eosinophils to the same site. * Sensitization of mast cells by IgE antibody. Mast cells are derived from precursors in the bone marrow, are widely distributed in tissues, and often reside near blood vessels and nerves and in subepithelial locations. Mast cells described in Chapter 2. Eosinophils are recruited by eotaxin express a high-affinity receptor for the Fc poion of the e heavy chain of IgE, called FceRI. Even though the serum concentration of IgE is very low (in the range of 1 to 100 ug/mL), the affinity of the mast cell FceRI recep- tor is so high that the receptors are always occupied by IgE. These antibody-bearing mast cells are \"sensitized\" to react if the antigen binds to the antibody molecules. Basophils are the circulating counterpas of mast cells. They also express FceRI, but their role in most immedi- ate hypersensitivity reactions is not established (since these reactions occur in tissues and not in the circula- tion). The third cell type that expresses FceRI is eosino- phils, which often are present in these reactions and also have a role in IgE-mediated host defense against hel- minth infections, described later. * Activation of mast cells and release of mediators. When a person who was sensitized by exposure to an allergen is reexposed to the allergen, it binds to multiple specific IgE molecules on mast cells, usually at or near the site of allergen entry. When these IgE molecules are cross- linked, a series of biochemical signals is triggered in the mast cells. The signals culminate in the secretion of various mediators from the mast cells. Three groups of mediators are the most impoant in different immediate hypersensitivity reactions (Fig. 4-8): Vasoactive amines released from granule stores. The gran- ules of mast cells contain histamine, which is released within seconds or minutes of activation. Histamine causes vasodilation, increased vascular permeability, smooth muscle contraction, and increased secretion of mucus. Other rapidly released mediators include adenosine (which causes bronchoconstriction and inhibits platelet aggregation) and chemotactic factors for neutrophils and eosinophils. Other mast cell granule contents that may be secreted include several neutral proteases (e.g., tryptase), which may damage tissues and also generate kinins and cleave comple- ment components to produce additional chemotactic and inflammatory factors (e.g., C3a) (Chapter 2). The granules also contain acidic proteoglycans (heparin, chondroitin sulfate), the main function of which seems to be as a storage matrix for the amines. Newly synthesized lipid mediators. Mast cells synthesize and secrete prostaglandins and leukotrienes, by the same pathways as do other leukocytes (Chapter 2). These lipid mediators have several actions that are impoant in immediate hypersensitivity reactions. Prostaglandin D2 (PGD2) is the most abundant media- tor generated by the cyclooxygenase pathway in mast cells. It causes intense bronchospasm as well as increased mucus secretion. The leukotrienes LTC4 and LTD4 are the most potent vasoactive and spasmo- genic agents known; on a molar basis, they are several thousand times more active than histamine in increas- ing vascular permeability and in causing bronchial smooth muscle contraction. LTB4 is highly chemotac- tic for neutrophils, eosinophils, and monocytes. Cytokines. Activation of mast cells results in the syn- thesis and secretion of several cytokines that are impoant for the late-phase reaction. These include TNF and chemokines, which recruit and activate leu- kocytes (Chapter 2); IL-4 and IL-5, which amplify th TH2-initiated immune reaction; and IL-13, which stimulates epithelial cell mucus secretion. In summary, a variety of compounds that act on blood vessels, smooth muscle, and leukocytes mediate type I hypersensitivity reactions (Table 4-2). Some of these com- pounds are released rapidly from sensitized mast cells and are responsible for the intense immediate reactions associ- ated with conditions such as systemic anaphylaxis. Others, such as cytokines, are responsible for the inflammation seen in late-phase reactions. Often, the IgE-triggered reaction has two well-defined phases (Fig. 4-9): (1) the immediate response, characterized by vasodilation, vascular leakage, and smooth muscle spasm, usually evident within 5 to 30 minutes after expo- sure to an allergen and subsiding by 60 minutes; and (2) a second, late-phase reaction that usually sets in 2 to 8 hours later and may last for several days and is characterized by inflammation as well as tissue destruction, such as mucosal epithelial cell damage. The dominant inflammatory cells in the late-phase reaction are neutrophils, eosinophils, and lymphocytes, especially TH2 cells. Neutrophils are recruited by various chemokines; their roles in inflammation were described in Chapter 2. Eosinophils are recruited by eotaxinTH2-initiated immune reaction; and IL-13, which stimulates epithelial cell mucus secretion. In summary, a variety of compounds that act on blood vessels, smooth muscle, and leukocytes mediate type I hypersensitivity reactions (Table 4-2). Some of these com- pounds are released rapidly from sensitized mast cells and are responsible for the intense immediate reactions associ- ated with conditions such as systemic anaphylaxis. Others, such as cytokines, are responsible for the inflammation seen in late-phase reactions. Often, the IgE-triggered reaction has two well-defined phases (Fig. 4-9): (1) the immediate response, characterized by vasodilation, vascular leakage, and smooth muscle spasm, usually evident within 5 to 30 minutes after expo- sure to an allergen and subsiding by 60 minutes; and (2) a second, late-phase reaction that usually sets in 2 to 8 hours later and may last for several days and is characterized by inflammation as well as tissue destruction, such as mucosal epithelial cell damage. The dominant inflammatory cells in the late-phase reaction are neutrophils, eosinophils, and lymphocytes, especially TH2 cells. Neutrophils are recruited by various chemokines; their roles in inflammation were described in Chapter 2. Eosinophils are recruited by eotaxin", "cop": 2, "opa": "T cell mediated cytotoxicity", "opb": "IgEmediated reaction", "opc": "IgG mediated reaction", "opd": "IgA mediated hypersensitivity reaction", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3954746e-99e6-4508-92d6-c01bc49325df", "choice_type": "single"} {"question": "A direct acting cholinomimetics that is lipid soluble and has been used in the treatment of glaucoma is", "exp": "Ref-KDT 6/e p98 Pilocarpine is a directly acting and physostigmine-acetylcholine is an indirectly acting cholinomimetic useful for glaucoma.", "cop": 3, "opa": "Acetylcholine", "opb": "Physostigmine", "opc": "Pilocarpine", "opd": "Neostigmine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "7c90d3e8-e247-480e-a08b-fbed98124b6d", "choice_type": "single"} {"question": "Circumflex scapular aery is a branch of", "exp": "Subscapular aery is the largest branch of the axillary aery, arising from its third pa. It runs along the lower border of the subscapularis to terminate near the inferior angle of the scapula. It supplies the latissimus dorsi and the serratus anterior. The Subscapular aery gives off a large branch, the circumflex scapular aery, which is larger than the continuation of the main aery. Ref : B D Chaurasia's Human Anatomy, seventh edition , volume 1, pg. no., 53.", "cop": 2, "opa": "Thyrocervical trunk", "opb": "Subscapular aery", "opc": "Subclan aery", "opd": "Aoa", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "b5d8e495-b59e-4b0a-895e-15f7b71a982c", "choice_type": "single"} {"question": "Sensory nerve supply of the palatine tonsils is by", "exp": "Glossopharyngeal and lesser palatine nerves supply palatine tonsilPalatine tonsilThe Palatine tonsils are two prominent masses situated one on either side between the glossopalatine and pharyngopalatine arches.Each tonsil consists fundamentally of an aggregation of lymphoid tissue underlying the mucous membrane between the palatine arches.In the child the tonsils are relatively (and frequently absolutely) larger than in the adultThe follicles of the tonsil are lined by a continuation of the mucous membrane of the pharynx, covered with stratified squamous epitheliumAeries supplying the tonsil are the:Dorsalis linguae from the lingualThe ascending palatine and tonsillar from the external maxillaryThe ascending pharyngeal from the external carotidThe descending palatine branch of the internal maxillaryA twig from the small meningeal.The veins end in the tonsillar plexus, on the lateral side of the tonsilThe nerves are derived from the sphenopalatine ganglion, and from the glossopharyngeal.", "cop": 3, "opa": "Greater Palatine nerve", "opb": "Trigeminal nerve", "opc": "Glossopharyngeal nerve", "opd": "Facial nerve", "subject_name": "Anatomy", "topic_name": null, "id": "77af96d6-2bd7-4e83-880b-4a4224e26969", "choice_type": "single"} {"question": "The Reynold's pentad of fever, jaundice, right upper quadrant pain, septic shock and mental status change is typical of", "exp": "Clinical features of cholangitis Characterized by charcot's triad: Abdominal pain + jaundice + fever Cholangitis may be either self-limited or toxic with severe illness, including jaundice, fever, abdominal pain, mental status changes, and hypotension (Reynold's pentad) Fever and chills are the MC presentation Ref: Sabiston 20th edition Pgno : 1507", "cop": 1, "opa": "Cholangitis", "opb": "Hepatitis", "opc": "Cholecystitis", "opd": "Pancreatitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "61a3d286-6bfd-4a5c-8792-7f5b1affc4e3", "choice_type": "single"} {"question": "If there is a superficial cut in the region of middle pa of posterior triangle of neck, patient will experience problem", "exp": "Roof of posterior triangle is formed by the investing layer of deep cervical fascia.Accessory nerve lies just deep to the investing layer at the middle of the posterior border of sternocleidomastoid muscle and across the posterior triangle and reaches the anterior border of trapezius, which it supplies.Shrugging of shoulder is an action of trapezius.", "cop": 3, "opa": "Adduction of arm", "opb": "Pronating scapula", "opc": "Shrugging of shoulder", "opd": "Abduction of arm", "subject_name": "Anatomy", "topic_name": null, "id": "4d25fc74-0b6e-4abf-b00e-7ae45f0c827f", "choice_type": "single"} {"question": "Kupffer cells are found in", "exp": "Ref Robbins 8/e p834; 7/e p79;9/e p102 Kupffer cells, also known as stellate macrophages and Kupffer-Browicz cells, are specialized macrophages located in the liver, lining the walls of the sinusoids. They form pa of the mononuclear phagocyte system.", "cop": 3, "opa": "Hea", "opb": "Lungs", "opc": "Liver", "opd": "Spleen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "061f9ef7-d35d-4858-b30a-e49816a963d8", "choice_type": "single"} {"question": "The cistern chyli are situated in", "exp": "CISTERNA CHYLI - This is an elongated lymphatic sac, about 5 to 7 cm long. It is situated in front of the first and second lumbar veebrae,immediately to the right of the abdominal aoa. It is overlapped by the right crus of the diaphragm. Its upper end is continuous with the thoracic duct. It is joined by the right and left lumbar and intestinal lymph trunks. The lumbar trunks arise from the lateral aoic nodes, and bring lymph from the lower limbs, the pelvic wall and viscera, the kidneys, the suprarenal glands, the testes or ovaries, and the deeper pas of the abdominal wall. The intestinal trunks bring lymph from the stomach, the intestine, the pancreas, the spleen, and the anteroinferior pa of the liver. The cisterna chyli may be replaced by anastomotic channels between the two lumbar trunks, or by dilatations of the lumbar trunks which join to form the thoracic duct. The intestinal trunks may thus join the cisterna chyli, the lumbar trunks, or the thoracic duct. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2 , pg.no. 371", "cop": 4, "opa": "Pelvis", "opb": "Thorax", "opc": "Neck", "opd": "Abdomen", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "24ea60ad-8a60-41e8-90cb-cc02ed596f7b", "choice_type": "single"} {"question": "Inhibitor of Apoptosis is", "exp": "Ref Robbins 9/e p55; Robbins 7/e p29 Conversely, if cells are exposed to growth factors and other survival signals, they synthesize anti-apoptotic members of the Bcl-2 family, the two main ones of which are Bcl-2 itself and Bcl-xL. These proteins antagonize Bax and Bak, and thus limit the escape of the mitochondrial pro-apoptotic proteins. Cells deprived of growth factors not only activate the pro-apoptotic Bax and Bak but also show reduced levels of Bcl-2 and Bcl-xL, thus fuher tilting the balance toward death. The mitochondrial pathway seems to be the pathway that is responsible for apoptosis in most situa- tions, as we discuss later.", "cop": 4, "opa": "P53", "opb": "Ras", "opc": "Myc", "opd": "Bcl_2", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "432f07af-2905-4b92-a77b-f50f847c23ec", "choice_type": "single"} {"question": "Urogenital diaphragm is not formed by", "exp": "Urogenital diaphragm consists of :?i) Two muscles :- Sphincter urethrae and deep transverse perinei (also called transverse perinei profundus).ii) Two fascia :- Inferior fasica of urogenital diaphragm (perineal membrane) and superior fascia of urogenital diaphragm.", "cop": 3, "opa": "Perineal membrane", "opb": "Transverse peronei", "opc": "Sphincter urethra", "opd": "Inferior fascia of urogenital diaphragm", "subject_name": "Anatomy", "topic_name": null, "id": "55bc1426-e702-4005-8cf6-f8fe4ad92f49", "choice_type": "single"} {"question": "Metacarpophalangeal joint is", "exp": "Ellipsoid(functionally) / condylar joints(structurally): 1. Wrist (radio-carpal joints) 2. Knuckle (metacarpophalangeal joint) 3. Atlanto - occipital joint Ellipsoid > condylar joints", "cop": 2, "opa": "Condylar", "opb": "Ellipsoid", "opc": "Saddle", "opd": "Hinge", "subject_name": "Anatomy", "topic_name": "Osteology", "id": "14f284bf-ba04-4d92-829a-82e897c3171e", "choice_type": "single"} {"question": "Fluconazole different from ketoconazole in that", "exp": "REF-KDT6/e p762) Ketoconazole is rarely used now a days because of several limitations. Impoant among them are: Poor oral bioavailability Limited CNS penetration Powerful inhibition of microsomal enzymes Anti-androgenic adverse effects like gynaecomastia Fluconazole is preferred agent because it has Very good oral absorption Maximum CNS penetration (therefore effective in cryptococcal meningitis). No inhibitorv action on microsomal enzymes No anti-androgenic propey.", "cop": 4, "opa": "It is not active by the oral route", "opb": "It is more potent inhibitor of drug metabolism", "opc": "It is not effective in Cryptococcal meningitis", "opd": "It is unlikely to produce anti androgenic side effects", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "eeb94e8d-43b5-4513-9eb6-10a8fec72ac5", "choice_type": "single"} {"question": "Morula is a stage of cell", "exp": null, "cop": 2, "opa": "8", "opb": "16", "opc": "32", "opd": "64", "subject_name": "Anatomy", "topic_name": null, "id": "562b77fc-1cc8-48c6-bc66-ff876b9fd79a", "choice_type": "single"} {"question": "Posterior gastric aery is a branch of", "exp": "The fundic branches of the stomach can be defined as a group of vessels that can arise either directly or indirectly from the following source aeries: the left inferior phrenic aery, the accessory left hepatic aery, the left gastric aery, the left middle suprarenal aery, the main trunk of the splenic aery Ref - BDC 6e vol2 pg277", "cop": 1, "opa": "Splenic aery", "opb": "Hepatic aery", "opc": "Left Gastric aery", "opd": "Right Hastric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "982bc630-53b0-4431-bc0c-24dfad256bed", "choice_type": "single"} {"question": "Taste sensation from anterior 2/3rd of tongue are carried by", "exp": "TASTE SENSATION FROM ANTERIOR TWO-THIRDS OF TONGUE IS CARRIED BY CHORDA TYMPANI. CHORDA TYMPANI IS THE NERVE OF TASTE EXCEPT VALLAA PAPILLAE. REFER BDC 6 TH EDITION VOLUME 3 PAGE NO: 268 REFER FIG 17.8", "cop": 2, "opa": "Glossopharyngeal", "opb": "Chordatympani", "opc": "Trigeminal", "opd": "Greater auricular", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6fb2cb3a-e2ec-4aad-8ab2-dd1993309337", "choice_type": "single"} {"question": "Largest cranial nerve", "exp": "SOME KEY FACTS ABOUT CRANIAL NERVES \n\nTrigeminal is the largest cranial nerve.\nVagus nerve is with vague or extensive distribution.\nOlfactory is the smallest cranial nerve.\n\niv) Trochlear nerve shows largest intracranial course.\n       v) Buccal nerve is the only sensory branch of anterior division of mandibular nerve\n       vi) Smallest branch of trigeminal nerve is ophthalmic. \n       vii) Smallest of three terminal branches of opthalmic nerve is lacrimal nerve and frontal nerve is largest terminal branch of opthalmic nerve.", "cop": 3, "opa": "Vagus", "opb": "Trochlear", "opc": "Trigeminal", "opd": "Olfactory", "subject_name": "Anatomy", "topic_name": null, "id": "b58354f5-d754-4d60-b520-ea7578a1b8b0", "choice_type": "single"} {"question": "Central aery of Retina is branch of", "exp": "Within the dural sheath, the ophthalmic aery gives off the central aery of the retina. after piercing the dura mater it gives off a large lacrimal branch that runs along the lateral wall of the orbit. the main aery runs towards the medial wall of the orbit giving off a number of branches. Notes: the central aery of retina is the only aerial supply to most of the nervous layer the retina of the eye.if this aery is blocked there is sudden blindness. Ref BDC volume 3;Sixth edition pg 209.", "cop": 3, "opa": "External carotid aery", "opb": "Internal carotid aery", "opc": "Ophthalmic aery", "opd": "Basilar aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "5cab817d-f60d-41f2-b8b5-81e802e1a515", "choice_type": "single"} {"question": "Aliskiren is a", "exp": "Aliskiren binds to the S3bp binding pocket of renin, essential for its activity . Binding to this pocket prevents the conversion of angiotensinogen to angiotensin I.", "cop": 3, "opa": "Endothelin receptor antagonist", "opb": "Antiplatelet", "opc": "Renin inhibitor", "opd": "Diuretic", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "de32b9df-fde2-4c06-9d12-9f316024ebfc", "choice_type": "single"} {"question": "Earliest lesion seen in asbestosis is", "exp": "It is most common manifestation of asbestos exposure composed of plaques of dense collagen containing calcium. They are usually asymptomatic and develop on anterior and posteriolateral pas of parietal pleura and over the diaphragm Refer robbins 9/e", "cop": 1, "opa": "A. Pleura plaques", "opb": "B. Hilar lymphadenopathay", "opc": "C. Adenoma lung", "opd": "D. Mesothelioma", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "27633b50-e480-4f72-adb4-0a50c2aaf36f", "choice_type": "single"} {"question": "Lymphatic drainage of cervix is to", "exp": "A. i.e. Iliac lymph nodes", "cop": 1, "opa": "Iliac lymph nodes", "opb": "Para aoic lymph nodes", "opc": "Superficial inguinal lymph nodes", "opd": "Deep inguinal lymph nodes", "subject_name": "Anatomy", "topic_name": null, "id": "a61bbfb0-c4a0-463f-94c9-324ade33e2a5", "choice_type": "single"} {"question": "In regeneration", "exp": "ref, Robbins 8/e p92-94 .7/e p 88,9/e p101 When the injury is minimal, the tissue may effectively replace the damaged or lost cells . In severely damaged tissues or long-term chronic situations, the ability of the tissue toregenerate the same cell types and tissuestructure may be exceeded, so that a different and imperfect repair occurs.", "cop": 2, "opa": "Granulation tissue", "opb": "Repairing by same type of tissue", "opc": "Repairing by different type of tissue", "opd": "Cellular proliferation is largely regulated by biochemical factors", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7913ebd4-8e36-4038-adbe-5449c6f387be", "choice_type": "single"} {"question": "Epitheliod granuloma is caused by", "exp": "ref Robbins 7/e p 83 CD 4 hepler cells are involved in granuloma formation as it secreted lFN - gamma, IL 2 ,IL 12 Histiocytes (specifically macrophages) are the cells that define a granuloma. They often, but not invariably, fuse to form multinucleated giant cells (Langhans giant cell). The macrophages in granulomas are often referred to as \"epithelioid\".", "cop": 3, "opa": "Neutrophils", "opb": "Cytotoxic T cells", "opc": "Helper T cells", "opd": "NK cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "60a09767-9f37-4194-805e-d5a8685a88a1", "choice_type": "single"} {"question": "In an outbreak of cholera in a village of 2,000 population, 20 cases have occurred and 5 died. Case fatality rate is", "exp": "(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 63)", "cop": 4, "opa": "1%", "opb": "0.25%", "opc": "5%", "opd": "25%", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1980e5e1-cee4-4dbd-a201-e65d8cb3bcaa", "choice_type": "single"} {"question": "Circulus iridis major is seen at", "exp": "Anterior ciliary aeries join with 2 long posterior ciliary aeries at root of iris", "cop": 4, "opa": "Ciliary body", "opb": "Pupillary margin", "opc": "Collarette", "opd": "Root of iris", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "8f4bbddd-9412-47e2-abca-052b4642e340", "choice_type": "single"} {"question": "Lining epithelium of vagina is", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:359Mucous membraneThe mucous membrane shows numerous longitudinal folds and is firmly fixed to the underlying muscle layer.it us lined by stratified squamous epithelium(non keratinized)", "cop": 3, "opa": "Pseudostratified columnar epithelium", "opb": "Keratinized stratified squamous epithelium", "opc": "Non keratinized stratified squamous epithelium", "opd": "Cliated columnar epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ce260192-ec97-429a-bd53-d8d5b6aafdf0", "choice_type": "single"} {"question": "The nerve supply of Middle ear is from", "exp": "(B) Tympanic branch of glossopharyngeal nerve# Sensory nerve supply of middle ear cavity is provided by Glossopharyngeal nerve.> Tympanic Plexus It lies on the promontory and is formed by tympanic branch of glossopharyngeal and sympathetic fibres from the plexus round the internal carotid artery.> Tympanic plexus supplies innervation to the medial surface of the tympanic membrane, tympanic cavity, mastoid air cells and the bony eustachian tube.> It also carries secretomotor fibres for the parotid gland. Section of tympanic branch of glossopharyngeal nerve can be carried out in the middle ear in Frey syndrome.> The tympanic cavity contains the tympanic plexus and the facial nerve. Branches from the plexus and the facial nerve supply structures within the tympanic cavity but also leave the cavity to supply structures on the face. The nerves that constitute the tympanic plexus ramify on the surface of the promontory on the medial wall of the tympanic cavity They are derived from the tympanic branch of the glossopharyngeal nerve and the caroticotympanic nerves. The former arises from the inferior ganglion of the glossopharyngeal nerve, and reaches the tympanic cavity via the tympanic canaliculus for the tympanic nerve. The superior and inferior caroticotympanic nerves are postganglionic sympathetic fibres which are derived from the carotid sympathetic plexus and traverse the wall of the carotid canal to join the plexus.", "cop": 2, "opa": "Superior auricular nerve", "opb": "Tympanic branch of glossopharyngeal nerve", "opc": "Pharyngeal branch of glossopharyngeal nerve", "opd": "Great auricular nerve", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "f8bedf6b-920d-4662-b365-4f3217a15c37", "choice_type": "single"} {"question": "Bifurcation of Trachea is at the level of", "exp": "Bifurcation of Trachea is at the level of Body of T6", "cop": 1, "opa": "Body of T6", "opb": "Lower border of T6", "opc": "Body of T4", "opd": "Lower border of T4", "subject_name": "Anatomy", "topic_name": null, "id": "c3150fd0-4863-4641-8f0a-dc9507531441", "choice_type": "single"} {"question": "The secretomotor fibre to the parotid gland passes through", "exp": "B. i.e. (Otic ganglion) (737- BDC-3 4th)* Parasympathetic secretomotor fibres from the inferior salivary nucleus of the 9th nerve supply the parotid gland. The nerve fibres pass to the otic ganglion via the tympanic branch of the 9th nerve and lesser petrosal nerve* Parotid duct (stenson duct) opens into the opposite the crown of the upper second molar tooth *** Structure within the parotid gland - from lateral to medial are facial nerve, retromandibular vein, external carotid artery, lymph node*** Taste fibres are the peripheral processes of the cells in the geniculate ganglion (712-Snell 8th)* Ciliary Ganglion - is a parasympathetic ganglion situated in the posterior part of the orbit and supply the sphincter pupillae and the ciliary muscle", "cop": 2, "opa": "Ciliary ganglion", "opb": "Otic ganglion", "opc": "Sub mandibular ganglion", "opd": "Geniculate ganglion", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "b1b6c389-88f5-47af-ae1f-abed49d42e1c", "choice_type": "single"} {"question": "Antibody found in patients with myasthenia gravis is directed against", "exp": "Ref Robbins 9/e p195 Myasthenia gravis Acetylcholine receptor Antibody inhibits acetylcholine binding, downmodulates receptors Muscle weakness, paralysis", "cop": 2, "opa": "Acetylcholine", "opb": "Acetylcholine receptor", "opc": "Acetylcholine vesicles in nerve terminals", "opd": "Actin myosin complex of the muscle", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cbc35b03-62e5-4709-bdda-3fc4d5aac58b", "choice_type": "single"} {"question": "Motor nerve supply of muscles of upper lip is by", "exp": "Temporal—frontalis, auricular muscles, orbicularis oculi \nZygomatic—Orbicularis oculi \nBuccal—muscles of the cheek and upper lip \nMarginal mandibular—muscles of lower lip. \nCervical—platysma", "cop": 3, "opa": "Temporal branch of facial nerve", "opb": "Zygomatic branch of facial nerve", "opc": "Buccal branch of facial nerve", "opd": "Marginal mandibular branch of facial nerve", "subject_name": "Anatomy", "topic_name": null, "id": "2c9f6268-9465-4049-a112-5da2871f7848", "choice_type": "single"} {"question": "Fear of pain is", "exp": "Acrophobia - fear of height Hydrophobia- fear of water Nyctophobia - fear of night Algophobia - fear of pain Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 361", "cop": 4, "opa": "Acrophobia", "opb": "Hydrophobia", "opc": "Nyctophobia", "opd": "Algophobia", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "4c9b4f7a-9772-4adb-8ad7-3b532b88dc93", "choice_type": "single"} {"question": "Basal lamina of blood vessel in CNS is secreted by", "exp": null, "cop": 1, "opa": "Endothelial cells", "opb": "Oligodendrocytes", "opc": "Microglia", "opd": "Astrocytes", "subject_name": "Anatomy", "topic_name": null, "id": "358dccee-4bd0-4aec-ac80-f8c12d9e3708", "choice_type": "single"} {"question": "A 40 year old male presents with a painless cystic liver enlargement of four years duration without fever or jaundice. The most likely diagnosis is", "exp": "Clinical features of hydatid disease Equally common in males and females, age 45 years Most(75%) are singular, located in right liver Mostly asymptomatic until complications occur Most common presenting symptoms - abdominal pain, dyspepsia and vomiting Most common sign- Hepatomegaly Ref:Sabiston 20th edition Pgno :1452", "cop": 3, "opa": "Amoebic liver abscess", "opb": "Hepatoma", "opc": "Hydatid cyst of liver", "opd": "Choledochal cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7d79a6da-fa13-40a6-a9e0-1b7a1c63093e", "choice_type": "single"} {"question": "Melanocytes are present in", "exp": "Melanoblasts, derived from neural crest, migrate to the epidermis and reside in the stratum basaleReference: Krishna Garg Histology; 5th edition; Page no: 113", "cop": 3, "opa": "Stratum Corneum", "opb": "Stratum Granulosum", "opc": "Stratum Basale", "opd": "Stratum Lucidium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cdec3aa9-92e6-4da2-9e5b-dcf87030fc05", "choice_type": "single"} {"question": "Testes completely descend in the scrotum by the aha of", "exp": "Testis lies at superficial ring at 8th month and enters the scrotum at the beginning of 9th month. It reaches the final position in the scrotum just before bih.", "cop": 3, "opa": "Ends of 7th month of intrauterine life", "opb": "End of 8th months of intrauterine life", "opc": "End of 9th months of intrauterine life", "opd": "After bih", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2c1aab71-0ae2-4e04-812f-94b9e74daa99", "choice_type": "single"} {"question": "Surgical lobes of liver are divided on the basis of", "exp": "Functional anatomy of the liver is based on couinaud's division of liver into eoght(subsequently nine) functional segments, based upon the distribution of poal venous branches and location of hepatic veins in the parenchyma Couinaud 1957", "cop": 2, "opa": "Hepatic aery", "opb": "Hepatic vein", "opc": "Bile ducts", "opd": "Central veins", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "06da6a39-ef70-4737-93b0-cf32eadf1146", "choice_type": "single"} {"question": "Characteristics of SLE of kidney is", "exp": "Ref Robbins 9/e p224 Kidneys. Kidney involvement is one of the most impoant clinical features of SLE, with renal failure being the most common cause of death. The focus here is on glomerular pathology, although interstitial and tubular lesions are also seen in SLE. The pathogenesis of all forms of glomerulonephritis in SLE involves deposition of DNA-anti-DNA complexes within the glomeruli. These evoke an inflammatory response that may cause proliferation of the endothelial, mesangial, and/or epithelial cells and, in severe cases, necrosis of the glomeruli. Although the kidney appears normal by light microscopy in 25% to 30% of cases, almost all cases of SLE show some renal abnormality if examined by immuno- fluorescence and electron microscopy. According to the current International Society of Nephrology/Renal Pathol- ogy Society morphologic classification, there are six patterns of glomerular disease in SLE (none of which is specific to the disease): class I, minimal mesangial lupus nephritis; class II, mesangial proliferative lupus nephritis; class III, focal lupus nephritis; class IV, diffuse lupus nephritis; class V, membra- nous lupus nephritis; and class VI, advanced sclerosing lupus nephritis. * Minimal mesangial lupus nephritis (class I) is rarely encountered in renal biopsies. Immune complexes are present in the mesangium, but there are no concomitant structural alterations detectable by light microscopy. * Mesangial proliferative lupus nephritis (class II) is seen in 10% to 25% of cases and is associated with mild clinical symptoms. Immune complexes deposit in the mesangium, with a mild to moderate increase in the mesangial matrix and cellularity. * Focal lupus nephritis (class III) is seen in 20% to 35% of cases. Lesions are visualized in fewer than half the glomeruli, and they may be segmentally or globally distrib- uted within each glomerulus. Active lesions are character- ized by swelling and proliferation of endothelial and mesangial cells, infiltration by neutrophils, and/or fibrinoid deposits with capillary thrombi (Fig. 4-18, A). The clinical presentation may range from only mild microscopic hema- turia and proteinuria to a more active urinary sediment with red blood cell casts and acute, severe renal insufficiency. * Diffuse lupus nephritis (class IV) is the most serious form of renal lesions in SLE and is also the most commonly encountered in renal biopsies, occurring in 35% to 60% of patients. It is distinguished from focal lupus nephritis (class III) by involvement of half or more of glomeruli. Most of the glomeruli show endothelial and mesangial prolifera- tion, leading to diffuse hypercellularity of these structures (Fig. 4-18, B) and producing in some cases epithelial crescents that fill Bowman's space. When extensive, sub- endothelial immune complexes create a circumferential thickening of the capillary wall, resembling rigid \"wire loops\" on routine light microscopy (Fig. 4-18, C). Electron microscopy reveals prominent electron-dense subendo- thelial immune complexes (between endothelium and basement membrane) (Fig. 4-18, D), but immune com- plexes are also usually present in other pas of the capil- lary wall and in the mesangium. Immune complexes can be visualized by staining with fluorescent antibodies directed against immunoglobulins or complement, result- ing in a granular fluorescent staining pattern (Fig. 4-18, E). In due course, glomerular injury may give rise to scarring (glomerulosclerosis). Most affected patients have hematu- ria with moderate to severe proteinuria, hypeension, and renal insufficiency. * Membranous lupus nephritis (class V) occurs in 10% to 15% of cases and is the designation for glomerular disease characterized by widespread thickening of the capillary wall due to deposition of subepithelial immune complexes. Membranous glomerulonephritis associated with SLE is very similar to that encountered in idiopathic membranous nephropathy (Chapter 13). Thickening of capillary walls is caused by increased deposition of base- ment membrane-like material, as well as accumulation of immune complexes. Patients with this histologic change almost always have severe proteinuria with ove nephrotic syndrome (Chapter 13). * Advanced sclerosing lupus nephritis (class VI) is characterized by complete sclerosis of greater than 90% of glomeruli and corresponds to clinical end stage renal disease.", "cop": 3, "opa": "Focal sclerosis", "opb": "Focal necrosis", "opc": "Wire loop lesion", "opd": "Diffused glomerulosclerosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "31e5fb4e-d480-46b1-8042-b081479c3d3c", "choice_type": "single"} {"question": "Vomer ala and sphenoidal rostrum junction is", "exp": "Spheno- vimerine joint is a schindylesis suture at the roof of the nasal cavity Ref: Gray's39e/p185-210", "cop": 3, "opa": "Syndesmosis", "opb": "Synostosis", "opc": "Schindylesis", "opd": "Gomphosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e4c626a1-8483-46b3-aa4d-1159cceac958", "choice_type": "single"} {"question": "Taeniae coli is found is", "exp": "(Ascending colon) (254-BDC-2 4th)Differences between small intestine and the large intestineFeaturesSmall IntestineLarge Intestine1. Appendices epiploicaeAbsentPresent*2. Taeniae coliAbsentPresent*3. SacculationsAbsentPresent4. DistensibilityLessMore5. FixityGreater part is freely mobileGreater part is fixed6. VilliPresentAbsent7. Transverse mucosal foldsPermanentObliterated when longitudinal muscle coat relaxes8. Peyer's patchesPresent in ileumAbsent9. Common site for(a) Intestinal worms(a) Entamoeba histolytica (b) Typhoid(b) Dysentery organism (c) Tuberculosis(c) Carcinoma10. Effect of infection and irritationDiarrhoeaDysentery", "cop": 4, "opa": "Duodenum", "opb": "Jejunum", "opc": "Ileum", "opd": "Ascending colon", "subject_name": "Anatomy", "topic_name": "Abdomen & Pelvis", "id": "7959f442-a1b0-4e74-a9e8-e8eb3d023601", "choice_type": "single"} {"question": "Muscle not having dual nerve supply", "exp": "Anterior belly of digastric is supplied by the trigeminal nerve and posterior belly by facial nerve Spinal accesory nerve and c3,c4 nerves supply Trapezius Ischial pa of sciatic nerve and the obturator nerve supply adductor magnus Ref: Gray's 39e/p112-127", "cop": 2, "opa": "Digastric", "opb": "Thyrohyoid", "opc": "Trapezius", "opd": "Adductor magnus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9bbfbe9b-5d44-4c4b-a898-7dd1d63bfbb1", "choice_type": "single"} {"question": "NK cells CD marker is", "exp": "Ref Robbins 8/e p188;9/e p192 NK cells (belonging to the group of innate lymphoid cells) are defined as large granular lymphocytes (LGL) and constitute the third kind of cells differentiated from the common lymphoid progenitor-generating B and T lymphocytes. NK cells are known to differentiate and mature in the bone marrow, lymph nodes, spleen, tonsils, and thymus, where they then enter into the circulation. NK cells differ from natural killer T cells (NKTs) phenotypically, by origin and by respective effector functions; often, NKT cell activity promotes NK cell activity by secreting interferon gamma. In contrast to NKT cells, NK cells do not express T-cell antigen receptors(TCR) or pan T marker CD3 or surface immunoglobulins (Ig) B cell receptors, but they usually express the surface markers CD16 (FcgRIII) and CD56 in humans", "cop": 1, "opa": "16", "opb": "60", "opc": "32", "opd": "25", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1ede52f9-4206-4a2b-b6de-3a1ee6d340d4", "choice_type": "single"} {"question": "In type II respiratory failure,there is", "exp": "Ref Harrison 19 th ed. pg1731-1732 Type II respiratory failure is characterized by decreased paO2 and incresinc paCO2 as a result of alveolar hypoventilation.there is fall in minute ventilation which causes a rise in PaCO2 and fall in PaO2. The alveolar aerial gradient is normal in Type 2 respiratory failure.", "cop": 2, "opa": "Low pO2 and low pCO2", "opb": "low pO2 and high pCO2", "opc": "Normal pO2 and high pCO2", "opd": "Low pO2 and normal pCO2", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "73475457-d8a1-4807-b508-cc6b8943a8d2", "choice_type": "single"} {"question": "Primordial Germ cells give rise to oogonium and then primary oocyte.PGCs themselves develop from", "exp": "Among the given options, yolk sac is the best answer. Primordial germ cells (PGC) forms germ cells which are derived from epiblast at the end of Week 2. These PGC migrates to endodermal layer of yolk sac at week 4 and fuher towards genital ridge by week 5. Aberrant migration of these PGC leads to teratomas: Sacrococcygeal teratoma Oropharyngeal teratoma", "cop": 1, "opa": "Epiblast", "opb": "Neural crest", "opc": "Coelomic epithelium", "opd": "Genital ridge", "subject_name": "Anatomy", "topic_name": "Introduction and gametogenesis.", "id": "a8f8393e-31c3-42a0-ac97-a5fbc94062c5", "choice_type": "single"} {"question": "The WORST prognosis in patients with endometrial carcinoma is found in patients with tumour involvement of the", "exp": "Involvement of the bladder mucosa constitutes a stage IV tumour. The other examples given are either stage II or III. The more advanced the stage of a tumour, the worse the prognosis.", "cop": 3, "opa": "Uterine cervix", "opb": "Upper vagina", "opc": "Bladder mucosa", "opd": "Parametrium", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d903d86e-350c-4776-804b-60e9795a7d0d", "choice_type": "single"} {"question": "Weight transmission from upper limb to axial skeleton is done by", "exp": "Ligaments involved in weight transmission connect one bone with the next bone, in line of weight transmission. Costoclavicular ligament transfers the weight of upper limb to axial skeleton.Coracoclavicular ligament transfer the weight of upper limb to clavicle bone.Note: Coracoacromial ligaments attach to bone scapula at different points and is not attached to the previous or next bone in line of weight transmission. They do not help in weight transmission.", "cop": 1, "opa": "Costoclavicular ligament", "opb": "Coracoacromial ligament", "opc": "Coracoclavicular ligament", "opd": "Interclavicular ligament", "subject_name": "Anatomy", "topic_name": "Upper limb bones and muscles (proximal region) & Scapular movements", "id": "0c22812c-62c7-4628-8ce6-281538ab4f0e", "choice_type": "single"} {"question": "Most common serotype of HPV associated with invasive cervical carcinoma is", "exp": ".", "cop": 1, "opa": "HPV 16", "opb": "HPV 18", "opc": "HPV 32", "opd": "HPV 36", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2a801e8e-ecd4-4804-bd16-98b6aa3754d9", "choice_type": "single"} {"question": "Retraction of scapula at sternoclavicular joint is done by (FMGE Dec 2018)", "exp": "Retractors of scapula: - 1. Trapezius 2. Rhomboid major 3. Rhomboid minor Protraction of scapula - done by 1. Pectoralis minor 2. Serratus anterior (damage causes winging of scapula) Subscapularis, supraspinatus along with infraspinatus & teres minor muscles connect scapula to humerus & provide suppo to glenohumeral joint (Rotator - cuff muscles) Muscle Origin Inseion Innervation Function Sub- scapularis Medial 2/3rd of subscapular fossa Lesser tubercle of humerus Upper & lower sub- scapular nerves (C5, C6, C7). Medial rotation of arm at glenohumeral joint Supraspinatus Medial 2/3rd of supra spinous fossa of scapula & deep fascia that covers muscle Most superior facet on greater tubercle of humerus Supra - scapular nerve (C5, C6) Abduction & stabilization of glenohumeral joint", "cop": 2, "opa": "Serratus anterior", "opb": "Trapezius", "opc": "Subscapularis", "opd": "Supraspinatus", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "4af0ff70-d403-47ff-988c-bfe7a300e006", "choice_type": "single"} {"question": "Root value ofsciatic nerve", "exp": "Ans. B.L4L5SlS2S3Root value of sciatic nerve is L4L5S1 S2S3", "cop": 2, "opa": "SIS2S3", "opb": "L4L5SlS2S3", "opc": "L2L3L4", "opd": "L1L2L3", "subject_name": "Anatomy", "topic_name": null, "id": "21bc7dcd-5bca-4ae9-9c47-08ba7ef0be6f", "choice_type": "single"} {"question": "The ductus aeriosus is derived from the following aoic arch", "exp": "The pa of the left sixth arch aery, between the branch to the lung bud and aoa,forms the ductus aeriosus HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:255", "cop": 4, "opa": "3rd", "opb": "4th", "opc": "5th", "opd": "6th", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "da965615-9a28-4c26-9f44-599a28adc6f8", "choice_type": "single"} {"question": "The colour coding of of 20G IV cannula is", "exp": null, "cop": 3, "opa": "Green", "opb": "Grey", "opc": "Pink", "opd": "Blue", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cde80903-c904-496a-950e-0bc4d54cc98e", "choice_type": "single"} {"question": "Middle lobe of prostate is present in between", "exp": "The prostate can be divided in two ways: by zone, or by lobe. It does not have a capsule; rather an integral fibromuscular band surrounds it.It is sheathed in the muscles of the pelvic floor, which contract during the ejaculatory process. Ref - BDC 6e vol2 pg403", "cop": 1, "opa": "Prostratic urethra & Ejaculation duct", "opb": "Prostratic urethra & rectum", "opc": "Ejaculation duet & pubis", "opd": "Pubis and rectum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fa6e7ec4-d27e-4b57-b771-c2c22287632b", "choice_type": "single"} {"question": "The spinal cord in infants ends at the level of", "exp": "C i.e. L3", "cop": 3, "opa": "L1", "opb": "L2", "opc": "L3", "opd": "La", "subject_name": "Anatomy", "topic_name": null, "id": "f232106d-ce47-426e-a1f7-f47274fa4681", "choice_type": "single"} {"question": "Failure of migration of neural crest cells is seen in", "exp": "Congenital megacolon (nirschsprung tiscase) due to failure of migration of neural crest to distal part of the tube so absence of para sympathetic myenteric acerbach's ganglia. Diseased segment is construction and the segmanr proximal is dilated due to faxical retention.", "cop": 2, "opa": "Albinism", "opb": "Congenital megacolon", "opc": "Odontomes", "opd": "Adrenal tumor", "subject_name": "Anatomy", "topic_name": null, "id": "daa29762-644b-4b63-8af3-6d0e6658222b", "choice_type": "single"} {"question": "Retention of Sodium is a side effect of", "exp": "(Refer: K. D. Tripathi&;s Essentials of Medical Pharmacology, 7th edition, pg no: 287-290)", "cop": 2, "opa": "Hydrocoisone", "opb": "Triamcinolone", "opc": "Prednisolone", "opd": "Coicosterone", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3a31685f-f5c7-4c76-b964-a9e13a111a3c", "choice_type": "single"} {"question": "Mastoid process antrum begins to develop in the", "exp": "*MASTOID* *ANTRUM* *DEVELOPEMENT* The antrum, which is the biggest of all mastoid air cells, stas its development between the 22nd and the 24th week of fetal life. It reaches its adult size on the 35th week The antrum develops at the center of the mastoid process on both sides of the petrosquamous fissure. The medial pa of the antrum, the petrous pa, develops from the saccus medius and the lateral pa, the squamous pa, develops from the saccus superior The fusion plane between the petrous pa and the squamous pa gives the petrosquamous fissure. Failure of complete fusion between the two sacci leads to a septation of the mastoid antrum by a bony paition called the Korner's septum Developmental arrest of the vestibule The antrum is well developed at bih and has a mean surface of 1 cm2 The size of the antrum does not change after bih; however, it undergoes medial displacement because of the growth of the mastoid process. The mastoid process continues to grow until pubey and even beyon REF : VISHRAM SINGH EMBRYOLOGY", "cop": 1, "opa": "6th month", "opb": "9th month", "opc": "1st year", "opd": "2nd year", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dbb3bf0d-e3f3-430c-9139-403a24f2fea7", "choice_type": "single"} {"question": "Immediate management of a patient with Multiple fracture and fluid loss includes the infusion", "exp": "Resuscitation following blood loss from multiple fractures begins with administration of 2-3 litres of isotonic crystalloid immediately to restore BP and peripheral circulation Lactated ringer (RL) solution is generally preferred over 0.9% NaCl (normal saline) as it is balanced salt solution and designed to mimic extracellular fluid Resuscitation with colloids is no more effective than crystalloids but is more expensive Ref: schwaz's principle of surgery 10th edition Pgno :109-110,119-123", "cop": 2, "opa": "Normal saline", "opb": "Ringer lactate", "opc": "Sag M", "opd": "Blood", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dc899b13-5bda-4890-8710-22d6406e735c", "choice_type": "single"} {"question": "Calcitonin is a marker of thyroid", "exp": "Refer Robbins page no Pg 1030 Medullary Thyroid Carcinomas. Familial medullary thyroid carcinomas occur in multiple endocrine neoplasia type 2 (MEN-2, see later) and are associated with germline RET mutations that lead to constitutive activation of the recep- tor. RET mutations are also seen in approximately one half of nonfamilial (sporadic) medullary thyroid cancers. Chromosomal rearrangements involving RET, such as the RET/PTC translocations repoed in papillary cancers, are not seen in medullary carcinomas.", "cop": 2, "opa": "Papillary carcinoma", "opb": "Medullary carcinoma", "opc": "Anaplstic carcinoma", "opd": "Adenocarcinoma", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "78f58662-b55d-4729-8f50-fbd6a57007f2", "choice_type": "single"} {"question": "Meissner&;s and Auerbach&;s plexus are divided from", "exp": "The myenteric plexus develops from the neural crest cells of the fetus. These cells then go through a series of migrations to situate along the future gastrointestinal tract. At three weeks of gestation, these cells move to the anterior foregut, where they are then referred to as enteric neural crest-derived cells (ENCDCs). Interestingly, neural crest cells induce the differentiation of surrounding muscular structures and interstitial cells of Cajal (ICC). In turn, these differentiate into the elements of the enteric nervous system, glial cells, and neurons. By week 9 of embryologic development, the myenteric plexus, circular muscle, and longitudinal muscle layers have formed along the entire gut.", "cop": 1, "opa": "Neural crest", "opb": "Yolk sac", "opc": "Primordial germ cell", "opd": "Epithelial lining of gut", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d130576e-9ffc-48db-9f30-7c99ec78e809", "choice_type": "single"} {"question": "Most common tumor producing osteoclastic metastasis", "exp": "Osteoblastic lesions are uncommon, they are usually are seen in prostatic carcinoma. However some other tumors may also produce Osteoblastic secondaries Refer ohopedic nuclear medicine 1st /e p 154", "cop": 3, "opa": "Kidney", "opb": "Lung", "opc": "Prostrate", "opd": "Thyroid", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "3bdd14eb-c6fd-4768-a6d7-2c90a457f1a6", "choice_type": "single"} {"question": "Deep branch of ulnar nerve supplies", "exp": "Muscles supplied by deep branch of ulnar nerve are - Muscles of hypothenar eminence, medial two lumbricals , 4-1 dorsal interossei muscles and 4-1 palmar interossei and adductor pollicis 1st and 2nd lumbricals are supplied by digital nerves from median nerve. Nerve supplying flexor digitorum superficialis comes from median nerve in the cubital fossa. B D Chaurasia 7th edition Page no: 182", "cop": 1, "opa": "Adductor pollicis", "opb": "Flexor digitorum superficialis", "opc": "1st Lumbrical", "opd": "2nd Lumbrical", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "b28130ab-1f97-4a49-a0c6-7c39ff59fc6f", "choice_type": "single"} {"question": "Simple Cuboidal Epithelium is present in", "exp": "The mucosal lining of the trachea is composed of pseudostratified ciliated columnar (respiratory) epithelium.The epithelial lining of bronchioles ranges from ciliated simple columnar with occasional goblet cells in larger bronchioles to simple cuboidal (many with cilia) with occasional club cells (also known as Clara cells) and no goblet cells in smaller bronchioles. The epithelium of terminal bronchioles is composed of club cells and cuboidal cells, some with ciliaRespiratory bronchioles are similar in structure to terminal bronchioles, in that their epithelium is a simple cuboidal epithelium rich in club cells and some ciliated cells, but this epithelium is broken up by the presence of thin-walled, pouch-like structures, known as alveoli, composed of an attenuated simple squamous epithelium, where gaseous exchange (O2 for CO2) can occur.Reference: Krishna Garg Histology; 5th edition; Page no: 130", "cop": 4, "opa": "Trachea", "opb": "Bronchioles", "opc": "Terminal Bronchiole", "opd": "Alveoli", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0d70c1df-9769-421f-bd8d-5f7aa02ded66", "choice_type": "single"} {"question": "Larynx extends from", "exp": "Larynx extends from the root of the tongue to the trachea.In the adult male it lies in front of the third to sixth cervical veebrae,but in children and in the adult female it lies at a little higher level. REF.BDC VOL.3,FIFTH EDITION", "cop": 2, "opa": "C2-C5", "opb": "C3-C6", "opc": "C5-T1", "opd": "C4-T1", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "31f9ec6a-a04b-4e94-9eed-6b475b70fff0", "choice_type": "single"} {"question": "Lamina papyracea separates nose from", "exp": "Ref: Henry Gray. Anatomy of the Human Body. The lateral surface is formed of a thin, smooth, oblong plate, the lamina papyracea (os planum), which covers in the middle and posterior ethmoidal cells and forms a large pa of the medial wall of the orbit; it aiculates above with the orbital plate of the frontal bone, below with the maxilla and orbital process of the palatine, in front with the lacrimal, and behind with the sphenoid.", "cop": 2, "opa": "Sphenoid bone", "opb": "Orbit", "opc": "Frontal bone", "opd": "Maxillary sinus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9c54f3fd-8e63-4b93-bca6-8dbf0c8e42a7", "choice_type": "single"} {"question": "Complications of tubercular meningitis are", "exp": "Refer Robbins page no1274 Options a and b are crct Most serious complications are Obliterative Endaeritis. Spinal roots may also be affected Calcification Tuberculoma. Arachnoid fibrosis", "cop": 1, "opa": "Endaeritis", "opb": "Hydrocephalus", "opc": "Deafness", "opd": "Venous sinus infarct", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "95e6e268-2961-40b7-b6b2-63ab4a73e070", "choice_type": "single"} {"question": "Obstruction of inferior vena cava presents as", "exp": "Inferior vena cava syndrome is a result of obstruction of the inferior vena cava. It can be caused by invasion or compression by a pathological process or by thrombosis in the vein itself.", "cop": 2, "opa": "Paraumbilical dilatation", "opb": "Thoracoepigastric dilatation", "opc": "Esophageal varices", "opd": "Hemorrhoids", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fee444d3-af7f-442a-ad74-988fcf829307", "choice_type": "single"} {"question": "Type II Mirizzi's syndrome", "exp": "Classification of Mirizzi's Syndrome (Csendes classification) Type I Obstruction of common duct by external compression only(no erosion) Type II Erosion of less than one-third circumference of common duct Type III Erosion of upto two-third circumference of common duct Type IV Total/near total circumferential destruction of common duct Type V Erosion of GB in common duct with cholecystoenteric fistula Ref: Sabiston 20th edition Pgno :1520", "cop": 2, "opa": "Obstruction of common duct by external compression only(no erosion)", "opb": "Erosion of one-thirds circumference of common duct", "opc": "Erosion of upto two-third circumference of common duct", "opd": "Total /near total circumferential of common duct", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "a25ecd08-c96d-4f98-9932-4038595cb408", "choice_type": "single"} {"question": "Heteopic calcification occurs in", "exp": "Ref, Robbins 7/e p41-2; Harrison 17/e p1952", "cop": 1, "opa": "Ankylosing spondylitis", "opb": "Rieter's syndrome", "opc": "Forrestier'disease", "opd": "Rheumatic ahritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "74ec0f7c-fceb-4ea5-ae75-e22bbc2a2a4f", "choice_type": "single"} {"question": "Locate the renal stone with pain radiating to medial side of thigh and perineum due to slipping of stone in males", "exp": "The clinician is able to judge the position of the stone by the history of pain - Ref : S. Das manual, 4/e p408", "cop": 1, "opa": "At pelvic brim", "opb": "Intramural opening of ureter", "opc": "Junction of ureter and renal pelvis", "opd": "At crossing of gonadal vessels and ureter", "subject_name": "Anatomy", "topic_name": "Urology", "id": "d383c0a7-1cf5-46ef-87ad-23e225e556be", "choice_type": "single"} {"question": "A woman has a fracture of the left tenth and eleventh ribs. The organ most likely to get injured by these fractured ribs is", "exp": "It is the most commonly injured organ in the abdomen.", "cop": 4, "opa": "Descending colon", "opb": "Jejunum", "opc": "Le adrenal gland", "opd": "Spleen", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9ade0c73-19c5-46e4-8357-233fae432230", "choice_type": "single"} {"question": "Principal cause of death in renal transplant patient", "exp": "Ref cambell's urology,8/e p346-349 * The graft rejection response is initiated mainly by host T cells that recognize the foreign HLA antigens of the graft, either directly (on APCs in the graft) or indirectly (after uptake and presentation by host APCs). * Types and mechanisms of rejection comprise the following: Hyperacute rejection: Pre-formed antidonor antibodies bind to graft endothelium immediately after transplanta- tion, leading to thrombosis, ischemic damage, and rapid graft failure. Acute cellular rejection: T cells destroy graft parenchyma (and vessels) by cytotoxicity and inflammatory reactions. Acute humoral rejection: Antibodies damage graft vasculature. Chronic rejection: Dominated by aeriosclerosis, this type is probably caused by T cell reaction and secretion of cytokines that induce proliferation of vascular smooth muscle cells, associated with parenchymal fibrosis. Principal cause of death is due to infection and inflammation", "cop": 4, "opa": "Uraemia", "opb": "Malignancy", "opc": "Rejection", "opd": "Infection", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f611ccb6-f829-4334-bddb-4a3d9687642f", "choice_type": "single"} {"question": "Branch of Pharmacology that deals with medicinal drugs obtained from plants and other natural sources is known as", "exp": ".", "cop": 1, "opa": "Pharmacognosy", "opb": "Pharmacogenomics", "opc": "Pharmacopoeia", "opd": "Chronopharmacology", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d59d8927-5350-41a9-bcef-148b5c07daf9", "choice_type": "single"} {"question": "Temporal lobe contains", "exp": "Primary auditory area (41,42) and secondary auditory area(22) both are in temporal lobe", "cop": 4, "opa": "Broca's area", "opb": "Prefrontal area", "opc": "Primary visual area", "opd": "Primary auditory area", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "5ff5f2c1-0fe5-4f4c-a25e-9f55d174844a", "choice_type": "single"} {"question": "Sec 299 IPC deals with", "exp": "Culpable homocide ( section 299 IPC) whoever causes death by doing an act, with the intention of causing death or with the intention for causing such bodily injury as likely to cause death, or cause death, commits the offence of culpable homicide Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 216", "cop": 2, "opa": "Assault", "opb": "Culpable homicide", "opc": "Murder", "opd": "Grievous hu", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "2774add4-7ea3-48f1-a950-9969fd90efeb", "choice_type": "single"} {"question": "Myelin sheath in the central nervous system is formed by", "exp": "Oligodendrocytes are responsible for myelination in the CNS. In the PNS, Schwann cells form the myelin sheath. The process of myelination begins before bih and is not complete until a year or more after bih. (Ref: Vishram Singh textbook of neuroanatomy, second edition, pg- 19)", "cop": 3, "opa": "Schwann cell", "opb": "Microglia", "opc": "Oligodendrocytes", "opd": "Protoplasmic astrocytes", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "f17ffc1c-1ad4-438a-8724-0bb55b7195d7", "choice_type": "single"} {"question": "In the mitogen activated protwin kinase pathway , the activation of RAS is counteracted by", "exp": "Ref Robbins 9/e p286 Activated rasvis present in association with GTP. Enzyme GTPase will degrade GTP to GDO and results in inactivation of RAS. Thus ,GTPase activating protein will counteract the activation of ras", "cop": 2, "opa": "Protein kinase C", "opb": "GTPase activating protein", "opc": "Phosphtidyl inositol", "opd": "Inositol triphosphate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a7c41960-641e-4c28-b80d-9734d007e3ba", "choice_type": "single"} {"question": "Nerve supply of tip of nose is", "exp": "The afferent component of corneal reflex is mediated through the ophthalmic branch of the trigeminal nerve. (V1 nerve).\nThe efferent component is mediate through the facial nerve (VIIth nerve).", "cop": 2, "opa": "Maxillary nerve", "opb": "Ophthalmic nerve", "opc": "Facial nerve", "opd": "Mandibular branch of Vth nerve", "subject_name": "Anatomy", "topic_name": null, "id": "4f670e28-9b94-434d-be43-da84870f797b", "choice_type": "single"} {"question": "Cells most sensitive to hypoxia are", "exp": "Ref , Robbins 8/e p11-2", "cop": 2, "opa": "Myocardial cells", "opb": "Neurons", "opc": "Hepatocytes", "opd": "Renal tubular epithelial cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a8aa9170-4cbf-4bc1-b3ca-ac7fb2a107e9", "choice_type": "single"} {"question": "A young patients presented with loss of sensation in sloe of foot with paralysis of medial side of plantar muscles of the foot, Most likely nerve involvement is", "exp": "(Tibial nerve) (172 - 74- BDC 4th edition) (660- Snell 8th)Common peroneal nerve injuryMotor- The muscles of the Anterior and lateral compartments of the leg are paralysed. As a result the opposing muscles, the planter flexors of the ankle joints and the invertors of the subtalar and transverse tarsal joints and the invertors of the subtalar and transverse tarsal joints, causes the foot to be plantar flexed (foot drop) and inverted and attitude reffered to as equinovarusSensory loss - Loss of sensation occurs down the anterior and lateral sides of the leg and dorsum of the foot and toesTibial Nerve InjuryMotor - All the muscles in the back of the leg and the sole of the foot are paralyzed. The opposing muscles dorsiflex the foot at the ankle joints and evert the foot at the subtalar and transverse tarsal joints, and attitude reffered to as calcaneo valgusSensory - Sensation is lost on the sole of the footDeep peroneal nerve injury - Paralysis of muscles of the anterior compartment of the leg results in loss of the power of dorsiflexion of the foot (Foot drop)", "cop": 4, "opa": "Common peroneal nerve", "opb": "Deep peroneal nerve", "opc": "Superficial peroneal nerve", "opd": "Tibial nerve", "subject_name": "Anatomy", "topic_name": "Lower Extremity", "id": "3b66ac04-7684-4e89-b435-754451332d89", "choice_type": "single"} {"question": "Nerve of Latarjet is seen in", "exp": "The nerve of Latarjet or the posterior nerve of the lesser curvature is a branch of the anterior vagal trunk which supplies the pylorus. BD CHAURASIA S HUMAN ANATOMY Vol 3", "cop": 3, "opa": "Thorax", "opb": "Neck", "opc": "Stomach", "opd": "Hea", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "08b35e30-45e3-430a-9a98-166bc60ee383", "choice_type": "single"} {"question": "Cause of odema", "exp": "Ref.robbins 8/e 112; 7/e 120- 121;9/e p114 Capillary blood contains a decreased quantity of colloids (protein-white circles) due to either decreased hepatic synthesis of these proteins or increased protein loss through the kidney or gastrointestinal tract. ... With decreased production of albumin the plasma colloidal osmotic pressure decreases and edema occurs.", "cop": 1, "opa": "Decreased plasma protein concentration", "opb": "Increased lymph flow", "opc": "Increased ECF", "opd": "Increased plasma proteins concentration", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "087c9231-57a9-4c92-99ae-849364aa6024", "choice_type": "single"} {"question": "Cremaster is supplied by", "exp": "Cremaster muscle Lies in scrotum Sensory supply to cremaster Laterally -Femoral Branch of genitofemoral nerve Medially - Ilioinguinal nerve Motor supply to cremaster Genital branch of genitofemoral nerve", "cop": 3, "opa": "Sacral plexus", "opb": "Femoral branch of genitofemoral nerve", "opc": "Genital branch of genitofemoral nerve", "opd": "Femoral nerve", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "98d4b830-c275-4c83-a90c-ffd3432dfa47", "choice_type": "single"} {"question": "A patient comes to the emergency depament with vomiting, diarrhea, lacrimation abdominal cramps, piloerection. The family members gave history of substance use for the past 1 month. The clinical presentation is due to", "exp": "In opioid withdrawal ALL ORIFICES BLEED Lacrimation, vomiting, rhinorrhea, diarrhea, mydriasis, kicking the habit, muscle cramps, abdominal cramps, tachycardia, cold turkey Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no.660", "cop": 2, "opa": "opiod intoxication", "opb": "opiod withdrawl", "opc": "cocaine intoxication", "opd": "cocaine withdrawl", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "b6e4d9d6-e491-40d3-9aae-fbe30eacd513", "choice_type": "single"} {"question": "Bacterial endocarditis is rarely seen in", "exp": "Ref Harrison 19 th ed pg 816 Infection most commonly involves hea valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving aeriovenous shunts, aerio-aerial shunts (patent ductus aeriosus), or a coarctation of the aoa is called infective endaeritis.", "cop": 4, "opa": "VSD", "opb": "PDA", "opc": "MVP", "opd": "Secundum ASD", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bc34b2bb-6b15-41dc-98bc-68838cbc9baa", "choice_type": "single"} {"question": "Ramu 40 year old man, chronic Alcoholic, diagnosed as cirrhosis, presents with a lump in the right lobe of liver. Serum AFP level is normal. Most probable diagnosis is", "exp": "This is a typical case of HCC, remember AFP is raised in about 75% of Africans and only 30% of patients in US and Europe Ref: Sabiston 20th edition Pgno :1458-1463", "cop": 2, "opa": "Fibro hyperplasia", "opb": "Hepatocellular carcinoma", "opc": "Secondaries", "opd": "Hepatic adenoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fb724bb4-cb91-4cf9-b0f5-91a7a738ee3a", "choice_type": "single"} {"question": "Primordial germ cells originate in the", "exp": "Primordial germ cells originate in the epiblast Primordial germ cells (PGCs), also known as primitive sex cells originate in the epiblast at the caudal end of the primitive streak. PGCs are the precursors of gametes in both genders. PGCs arise in the epiblast during the 2nd week of development. They pass through the primitive streak during gastrulation and reach the wall of the yolk sac. They migrate from the yolk sac at the 4th week and reach the developing gonads by the end of the 5th week. Ref: Gray&;s Anatomy 41st edition Pgno: 184", "cop": 2, "opa": "Gonads at the 4th week of embryonic develpment", "opb": "Epiblast at 2nd week of embryonic development", "opc": "Gonads at 2nd month of embryonic development", "opd": "Yolk sac at 4th week of embryonic development", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "87aa9a79-406d-4874-b3f7-975a24837f22", "choice_type": "single"} {"question": "A patient presented with midline pain at the marked dermatome (shaded in green). Select the best possible answer, as a differential diagnosis", "exp": "The green shaded area is the umbilical region, carrying T10 dermatome. Referred pain of mid-gut derivatives is felt in the peri-umbilical region (T - 10). Meckel's diveiculum is a mid-gut anomaly, presenting with pain around the umbilicus.", "cop": 2, "opa": "Angina pectoris", "opb": "Meckel's diveiculum", "opc": "Acute cholecystitis", "opd": "Renal colic", "subject_name": "Anatomy", "topic_name": "Umblicial cord and diaphragm", "id": "2227e917-bbf2-44ae-99aa-dbb36bdc51f6", "choice_type": "single"} {"question": "Muscle of expiration", "exp": "MUSCLE OF INSPIRATION: Quiet: Diaphragm External intercostals Interchondral pa of internal intercostal of contralateral side. Deep: Erector spinae Scalene muscles Pectoral muscles Serratus anterior MUSCLE OF EXPIRATION: Quiet: Passive process d/o inherent quality of lungs Forced: Muscles of anterior abdominal wall with internal intercostal (except interchondral pa)", "cop": 3, "opa": "External intercostal", "opb": "Diaphragm", "opc": "Internal intercostal", "opd": "Serratus anterior", "subject_name": "Anatomy", "topic_name": "Surfaces and Grooves", "id": "06de1146-f777-4e6b-89be-b2565d942c7a", "choice_type": "single"} {"question": "The preferred bypass procedure in case of nonresctable carcinoma of head of pancreas is", "exp": "Palliative surgery in Advanced, Non-resectable pancreatic Association Surgery for advanced, non resectable pancreatic adenocarcinoma can palliate obstruction of CBD or duodenum, as well as control visceral pain Hepaticojejunostomy, choledochojejunostomy or choledochoduodenostomy offers durable drainage of an obstructed bile duct. Choledochojejunostomy is less reliable but can be employed when tumor bulk precludes common duct procedure Ref: Devita 9th edition Pgno : 979", "cop": 4, "opa": "Cholecystojejunostomy", "opb": "Cholecystogastrostomy", "opc": "Choledochoduodenostomy", "opd": "Choledochojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1431c4b9-245a-45ac-a729-a64eb20da536", "choice_type": "single"} {"question": "Indication for prophylaxis in pneumocystis carinii pneumonia include", "exp": "Defects in cellular and/or humoral immunity predispose to development of PCP. CD4+ T cells are critical in host defense against Pneumocystis. For HIV-infected patients, the incidence is inversely related to the CD4+ T cell count: at least 80% of cases occur at counts of <200 cells/mL, and most of these cases develop at counts of <100 cells/mL. Ref Harrison 19th edition pg 1017", "cop": 1, "opa": "CD4 count <200 /ul", "opb": "Tuberculosis", "opc": "Vital load >25000 copies/ml", "opd": "Oral candidiasis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "d3fbe568-f091-4a11-8ee7-c616d57f7c69", "choice_type": "single"} {"question": "Tonsil is lined by", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:144The palatine tonsilsEach palatine tonsils consists of diffuse lymphoid tissue in which lymphatic nodules are present. the lymphoid tissue is covered by stratified squamous epithelium continuous with that of the mouth and pharynx", "cop": 2, "opa": "Stratified squamous keratinised epithelium", "opb": "Stratified squamous non keratinised epithelium", "opc": "Columnar epithelium", "opd": "Cuboidal epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "59dc83f7-9915-4250-bced-9d827dc2da21", "choice_type": "single"} {"question": "Common carotid aery is derived from", "exp": "The common carotid aery is derived, on either side, from pa of the third arch aery, proximal to the external carotid bud.The internal carotid aery is formed by the poion of the third arch aery distal to the budReference: Inderbir Singh Embryology; 10th edition; Page no: 260", "cop": 3, "opa": "Distal pa of 3rd Arch Aery and Cervical pa of Dorsal Aoa", "opb": "As a bud from 3rd Arch Aery", "opc": "Proximal pa of 3rd Arch Aery", "opd": "Truncus Aeriosus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0cd9b8f9-9069-4afe-861d-eb38c49ee64a", "choice_type": "single"} {"question": "Paralysis of 3rd, 4th, 6th nerves with involvement of ophthalmic division of 5th nerve,localizes the lesion to", "exp": "3,4,5 cranial nerves pass in relation to the lateral wall of cavernous sinus. 6th cranial nerve passes through the cavernous sinus. Ref - BDC 6th vol3 topic - cranial nerves ;pg350", "cop": 1, "opa": "Cavernous sinus", "opb": "Apex of orbit", "opc": "Brainstem", "opd": "Base of skull", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "88e19176-87ce-434c-ae12-7f1c646c4755", "choice_type": "single"} {"question": "A midline protrusion in maxillary region is mostly due to", "exp": "Torus means an elevation. Different types according to location: Torus palatinus: - Midline elevation of exaggerated bony growth at intermaxillary suture region specifically in the midline Torus maxillaris: - Exaggerated bony growth at either inner side of alveolar process or at outer side of alveolar process (either side of teeth) Torus mandibularis: - Exaggerated bony growth - near the premolar & above the mylohyoid line. Torus tubaris: - Mucosal elevation in nasopharynx at opening of the eustachian tube.", "cop": 1, "opa": "Torus palatinus", "opb": "Torus maxillaris", "opc": "Torus mandibularis", "opd": "Torus tubarius", "subject_name": "Anatomy", "topic_name": "Osteology", "id": "d69827f8-bf6b-4fc2-838e-b2cfb7273ca4", "choice_type": "single"} {"question": "Facial nerve supplies", "exp": "Facial nerve is the motor nerve of the face. its five terminal branches, temporal, zygomatic, buccal, marginal mandibular and cervical emerge from the parotid gland and diverge to supply the various facial muscles as follows. Temporal - frontalis, auricular muscles,orbicularis oculi. Zygomatic- orbicularis oculi. Buccal- muscles of the cheek and upper lip Marginal mandibular- muscles of lower lip. Cervical - platysma Ref BDC volume 3; sixth edition", "cop": 1, "opa": "Risorius", "opb": "Anterior belly of digastric", "opc": "Lateral pterygoid", "opd": "Zygomaticus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "36a88ca2-f645-46e3-b9f0-aa53b6698f66", "choice_type": "single"} {"question": "Bifurcation of trachea is at", "exp": "Trachea bifurcates at the lower border of fouh thoracic veebrae. BA CHAURASIA'S HUMAN ANATOMY VOLUME 1. 6TH EDITION.page no-280", "cop": 2, "opa": "Upper border of T5", "opb": "Lower border of T4", "opc": "Upper border of T4", "opd": "Lower border of T5", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "682aaa77-f36e-40bd-bcaa-8817f7f46eea", "choice_type": "single"} {"question": "Trochlear nerve supplies", "exp": "A. i.e. (Superior oblique) (115-BDC-3 4th)* Trochlear nerve - is very long and slender nerve supplies only the superior oblique muscle of the eye ball* Abducent - is a small motor nerve supplies the lateral rectus muscle**", "cop": 1, "opa": "Superior oblique", "opb": "Inferior oblique", "opc": "Lateral rectus", "opd": "Inferior rectus", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "da9554ef-1037-4bbf-88ee-302217f9c4eb", "choice_type": "single"} {"question": "Chief Extensor at knee joint is", "exp": "Quadriceps femoris is knee Extensor. Hamstrings (Biceps femoris long head, Semitendinosus, Semimembranosus and Adductor magnus) are Knee Flexors.", "cop": 2, "opa": "Biceps femoris", "opb": "Quadriceps femoris", "opc": "Semitendinosus", "opd": "Semimembranosus", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "5c0f299d-3461-4f8b-8469-26c97fdfc7ee", "choice_type": "single"} {"question": "Other than the spleen, occlusion of the splenic aery at its origin will most likely affect the blood supply to", "exp": "The sho gastric aeries arise from the Splenic aery at the hilum of the spleen and pass forward in the gastrosplenic omentum (ligament) to supply the fundus of the stomach.", "cop": 3, "opa": "Jejunum", "opb": "Head of the pancreas", "opc": "Fundus of the stomach", "opd": "Duodenum distal to the entrance of the common bile duct", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "bbee660e-1bbd-4e25-8257-247cfe372dba", "choice_type": "single"} {"question": "Secreting active thyroid follicles are lined by", "exp": "Thyroid follicles lining epithelium depends upon the secretion of thyroxine More the secretion,more the endoplasmic reticulum,more the height of the cell, becoming columnar. Resting follicle - Squamous Normal follicle - Cuboidal Active follicle - Columnar Ref: IB Singh textbook of histology 6e pg 325.", "cop": 1, "opa": "Columnar", "opb": "Cuboidal", "opc": "Squamous", "opd": "Pseudo stratified squamous", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d800539a-ee1e-4c2d-93b5-225f2b7b26b5", "choice_type": "single"} {"question": "Transpyloric plane separates", "exp": "Transpyloric plane cuts through the pylorus of the stomach, the tips of the ninth costal cailages and the lower border of the first lumbar veebra. Seperates hypochondrial and lumbar regions BD chaurasias Anatomy sixth edition Volume 2 Page no 197", "cop": 2, "opa": "Hypogastrium from lumbar region", "opb": "Hypochondrium from lumbar region", "opc": "Iliac fossa from lumbar region", "opd": "Umbilical region from lumbar region", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "20cb3af4-0504-4627-b2aa-7ddeacb7dae7", "choice_type": "single"} {"question": "Insensible loss of water per day is", "exp": ".", "cop": 3, "opa": "400 ml", "opb": "500ml", "opc": "700ml", "opd": "1000ml", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e98cbce0-a170-4d3f-a41f-509466cd73c6", "choice_type": "single"} {"question": "The first indication of gastrulation in the embryo is", "exp": "The formation of the primitive streak on the dorsal surface of the bilaminar embryonic disk formed from proliferation at the end of 2nd week (day 14) is the first indication of gastrulation.", "cop": 1, "opa": "Formation of the primitive streak", "opb": "Formation of the notochord", "opc": "Formation of the neural tube", "opd": "Formation of extraembryonic mesoderm", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "4bf78e3c-bab3-4e82-9883-cd7c303d8005", "choice_type": "single"} {"question": "Wellen's syndrome suggests", "exp": ".", "cop": 2, "opa": "Stable angina", "opb": "Unstable angina", "opc": "Lugwig's angina", "opd": "Prinzmetal angina", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2503d254-8a1b-4154-9f9c-046a7b0da682", "choice_type": "single"} {"question": "Parasympathetic postganglionic fibres are carried by the", "exp": "Long ciliary nerves are mixed sensory and sympathetic. Greater petrosal nerves carries preganglionic parasympathetic fibers from the facial nerve to the pterygopalatine ganglion. The deep petrosal nerve carries mainly sympathetic fibres from the superior cervical ganglion and internal carotid plexus.", "cop": 3, "opa": "Long ciliary nerves", "opb": "Greater petrosal nerves", "opc": "Auriculotemporal nerve", "opd": "Deep petrosal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "98d12a39-9c30-4486-81ae-e9fafcc0acaa", "choice_type": "single"} {"question": "Urothelium", "exp": "Inderbir Singh's Human Histology Pg A16 Membranous urethra is lined by transitional epithelium or urothelium", "cop": 4, "opa": "Ureters", "opb": "Minor calyx", "opc": "Urinary bladder", "opd": "Membranous Uretha", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6f0243ef-8364-4c8f-b304-f751c85ab758", "choice_type": "single"} {"question": "Accessory obturator aery is a branch of", "exp": "Accessory obturator aery is the pubic branch of the inferior epigastric aery. It contributes a significant supply through the obturator canal. Ref - semantischolar.org", "cop": 4, "opa": "Femoral aey", "opb": "Obturator aey", "opc": "Profunda femoris", "opd": "Inferior epigastric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "55c6dd0a-460c-4dfb-abb7-fc7395e7501c", "choice_type": "single"} {"question": "Parasympathetic nerve supply to salivary glands is by", "exp": null, "cop": 1, "opa": "VII and IX cranial nerves", "opb": "IX and X cranial nerves", "opc": "V and X cranial nerves", "opd": "VII and IX spinal nerves", "subject_name": "Anatomy", "topic_name": null, "id": "8c8d321e-ec27-43e7-8176-9a1f187a49f3", "choice_type": "single"} {"question": "Cell cycle specific anticancer drugs that acts mainly in the M phase of the cycle is", "exp": "Ref-KDT 6/830 Vinca alkaloids (vincristine, vinblastine and vinoerlbine ) and taxanes (pacilaxel and docetaxel) act in M-phase of cell cycle Vinca alkaloids inhibits the formation whereas taxenes inhibit the breakdown of mitotic spindle", "cop": 4, "opa": "Cisplatin", "opb": "Etoposide", "opc": "Methotrexate", "opd": "Paclitaxel", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "0e832f9e-dff2-4c1e-bf47-2b4d7838df10", "choice_type": "single"} {"question": "Transverse facial aery is the branch of", "exp": "Superficial Temporal Aery It is the smaller terminal branch of the external carotid aery. It begins, behind the neck of the mandible undercover of the parotid gland.In addition to the branches which supply the temple, the scalp, the parotid gland, the auricle and the facial muscles, the superficial temporal aery gives off a transverse facial aery and a middle temporal aery.Reference: Chourasia; 6th edition; 72nd page", "cop": 3, "opa": "Facial aery", "opb": "Maxillary aery", "opc": "Superficial Temporal aery", "opd": "Occipital aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1aada981-01ec-4942-ad0f-cfbb5db8a652", "choice_type": "single"} {"question": "Hypothayoidism is seen in", "exp": "Refer Robbins page no 1087 Hashimoto thyroiditis most often comes to clinical attention as painless enlargement of the thyroid, usually associated with some degree of hypothyroidism, in a middle-aged woman. The enlargement of the gland is usually symmetric and diffuse, but in some cases it may be sufficiently localized to raise the suspicion of a neoplasm. In the usual case, hypothyroidism develops gradually. In some patients, however, it may be preceded by transient thyrotoxicosis caused by disruption of thyroid follicles, leading to release of thyroid hormones (\"hashitoxicosis\"). During this phase, free T4 and T3 levels are elevated, TSH is diminished, and radioactive iodine uptake is decreased. As hypothyroidism supervenes, T4 and T3 levels fall, accompanied by a compensatory increase in TSH.", "cop": 1, "opa": "Hashimotos thyroiditis", "opb": "Graves disease", "opc": "Toxic multinodular goitre", "opd": "Struma ovarii", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "159978f8-9a5c-420b-9566-31da003cdf06", "choice_type": "single"} {"question": "Damage to nervous tissue is repaired by", "exp": "Refer Robbins page no Pg 1252", "cop": 1, "opa": "Neuroglia", "opb": "Fibroblasts", "opc": "Axons", "opd": "Microglia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "07e88501-5432-45a1-b3c2-a2c317427fd3", "choice_type": "single"} {"question": "Inferior epigastric aery forms the boundry of", "exp": "HESSELBACH&;S TRIANGLE:-Boundaries-1. Medially-Lateral border of rectus abdominis2. Laterally- inferior epigastric aery.3. Base - inguinal ligament.FEMORAL TRIANGLE:-Triangular depression on front of the upper one third of the thigh immediately below the inguinal ligament.BOUNDARIES :-1. Laterally: medial border of saorius.2. Medially: medial border of adductor longus.3. Base: inguinal ligament.4. Apex:directed downwards.formed by the point where the medial and lateral boundaries cross.apex is continuous with the adductor canal.5. Roof: skin,superficial fascia and deep fascia.Superficial fascia contains superficial inguinal lymph nodes,femoral branch of genitofemoral nerve,branches of ilioinguinal nerve,superficial branches of the femoral aery with accompanying veins and the upper pa of the great saphenous vein.6. Floor: medially by adductor longus and pectineus,and laterally by the psoas major and iliacus. CONTENTS:-1. Femoral aery and its branches.- Superficial branches-superficial external pudendal, Superficial epigastric and Superficial circumflex iliac Deep branches-profunda femoris, muscular branches and deep external pudendal2. Femoral vein and its tributaries3. Femoral sheath4. Femoral nerve5. Nerve to pectineus6. Femoral branch of genitofemoral nerve.7. Lateral cutaneous nerve of thigh.8. Deep inguinal lymph nodes.Vein is medial to aery (base)Vein posteromedial to aery (apex){Reference:BDC 6E pg no. 45}", "cop": 2, "opa": "Femoral triangle", "opb": "Hesselbach's triangle", "opc": "Adductor canal", "opd": "Popliteal triangle", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "0a70655c-5965-4933-a0da-765d5ddddae5", "choice_type": "single"} {"question": "Torus aoicus is an impression in the cavity of", "exp": "Torus aoicus (aoic mound) is the prominent region of the right atrial septum, which marks the projection of the non-coronary aoic sinus into the right atrial wall. The bulge is superior to the coronary sinus and anterior to the fossa ovalis.", "cop": 1, "opa": "Right atrium", "opb": "Right ventricle", "opc": "Left ventricle", "opd": "Left atrium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2d2f06d8-6f74-438d-b739-20714682240a", "choice_type": "single"} {"question": "Glycolipids are mostly found in", "exp": "Glycolipids are mostly seen in Brain and spinalcord Two types of glycolipids are : ganglioside ,cerebroside", "cop": 2, "opa": "Hea", "opb": "Brain", "opc": "Spinalcord", "opd": "Tetanus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3ce78960-74cb-49d1-95d9-5bb949cd9ce1", "choice_type": "single"} {"question": "Stimulation of the following receptor produce renin", "exp": "Beta 1 receptors are present opn JG apparatus producing increased renin.", "cop": 3, "opa": "Alpha 1", "opb": "Alpha 2", "opc": "Beta 1", "opd": "Beta 2", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cc237a72-0626-4246-b272-2d74b799247e", "choice_type": "single"} {"question": "AFP is elevated in", "exp": ".", "cop": 1, "opa": "HCC", "opb": "Infant hemangioendothelioma", "opc": "Amoebic liver abscess", "opd": "Embryonic sarcoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "09f49e40-5471-4d12-b873-44f2e7412082", "choice_type": "single"} {"question": "Surface marking of the mitral valve is", "exp": "Surface marking of mitral value is an oblique line 3 cm behind the left half of sternum opposite left 4th coastal cailage. BD CHAURASIA'S HUMAN ANATOMY.VOLUME 1.6TH EDITION.PAGE NO 291.TABLE 21.1:SURAFACE MARKING OF CARDIAC VALVE", "cop": 1, "opa": "Behind sternal end of left 4th costal cailage", "opb": "Behind sternal end of right 4th costal cailage", "opc": "Left 4th intercostal space in the midclavicular line", "opd": "Left 3rd intercostal space in the midclavicular line", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "ded5a773-6dd9-4523-82d6-f1d5b1fc9925", "choice_type": "single"} {"question": "CYP 450 inducers are", "exp": "P-450 inducers are: Phenobarbitone, rifampicin, phenytoin, chloe hydrate, phenylbutazone, griseofulvin, DDT, an chronic alcohol ingestion. Ketoconazole and cimetidine inhibit the drug metabolizing enzymes. Ref-KDT 7/e p26", "cop": 3, "opa": "Cimetidine", "opb": "Ketokonazole", "opc": "Phenobarbitone", "opd": "Theoplylline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3feba108-9027-433a-80a9-611adf025d29", "choice_type": "single"} {"question": "Perilymph enters the subarachnoid space the", "exp": "C. The perilymph enters the subarachnoid space of the posterior cranial fossa the cochlear aqueduct, which contains the perilymphatic duct.", "cop": 3, "opa": "Cochlear duct", "opb": "Ductus Reuniens", "opc": "Perilymphatic Duct", "opd": "Vestibular Aqueduct", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "59e6ea8e-a5aa-4e53-a92d-e4fd5afb7b23", "choice_type": "single"} {"question": "The approximate no of genes contained in human genome", "exp": "Humans have a mere 30,000 genes rather than the 100000 predicted only recently . Recent ribbons mention the no of genes 20,000 to 25,000 Ribbons 7th/219", "cop": 2, "opa": "A. 40,000", "opb": "B. 30,000", "opc": "C. 80,000", "opd": "D. 1,00,000", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3237cac7-65d9-4859-b5b6-1ca98694ddd1", "choice_type": "single"} {"question": "Meckel's diverticulum is a remnant of", "exp": null, "cop": 4, "opa": "Stenson's duct", "opb": "Wolffian duct", "opc": "Mullerian duct", "opd": "Vitellointestinal duct", "subject_name": "Anatomy", "topic_name": null, "id": "ae13ccf8-543a-46f2-a63a-6230584ee90c", "choice_type": "single"} {"question": "Gold standard investigation for screening of breast carcinoma in patients with breast implant", "exp": "MRI Indicated in scarred breast, implants and borderline lesions for breast conservation Investigation of choice for implant related complications Gold standard for imaging breast in females with implants Ref: Sabiston 20th edition pgno: 826-828", "cop": 1, "opa": "MRI", "opb": "USG", "opc": "Mammography", "opd": "CT- Scan", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "a17e0a12-f553-4be2-bd2e-6873b37e98b8", "choice_type": "single"} {"question": "ARDS is due to defect in", "exp": "ALI/ARDS is initiated by injury of pneumocytes and pulmonary endothelium. Setting in motion a vicious cycle of increasing inflammation and pulmonary damage", "cop": 4, "opa": "A. Hypoxemia", "opb": "B. Hypotention", "opc": "C. Clara cells", "opd": "D. Endothelial cells", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "096c9f13-6623-4601-951f-a721197b5c6d", "choice_type": "single"} {"question": "Blood can be stored with CPD A for", "exp": "Blood can be stored for 21 days with CPD ( Citrate phosphate dextrose ) Blood can be stored upto 35 days with CPD A ( Citrate phosphate dextrose adenine )", "cop": 3, "opa": "15 days", "opb": "21 days", "opc": "30 days", "opd": "45 days", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3ebbda28-a3d6-4852-92ef-da6c41dd21d1", "choice_type": "single"} {"question": "The stria of Gennari is a histological feature of", "exp": "Variations in Coical Structure -The structure of the cerebral coex shows considerable variation from region to region, both in terms of thickness and in the prominence of the various laminae described above. Finer variations form the basis of the subdivisions into Brodmann's areas. Other workers divide the coex into five broad varieties. These are as follows. In the agranular coex the external and internal granular laminae are inconspicuous. This type of coex is seen most typically in the precentral gyrus (area 4) and is, therefore, believed to be typical of 'motor' areas. It is also seen in some other areas. In the granular coex the granular layers are highly developed while the pyramidal and ganglionic layers are poorly developed or absent. In the visual area the external band of Baillarger is prominent and forms a white line that can be seen with the naked eye when the region is freshly cut across. This stria of Gennari gives the name striate coex to the visual coex. Between the two extremes represented by the agranular and granular varieties of coex, three intermediate types are described as follows. Frontal coex Parietal coex and Polar coex. The frontal type is nearest to the agranular coex, the pyramidal cells being prominent, while the polar type is nearest to the granular coex. REF: Inderbir Singh's Textbook of Human Histology, Seventh edition, pg.no., 190.", "cop": 3, "opa": "Motor speech area", "opb": "Auditory area", "opc": "Visual area", "opd": "Prefrontal area", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b6c837e1-edcd-4c85-a311-a839453939ae", "choice_type": "single"} {"question": "Spinal epidural space contains", "exp": "Epidural space This is the interval which seperates the periosteum in the veebral canal from the spinal duramater.The space is filled with loose areolar tissue,semiliquid fat,a network of veins,and the small aeries which supply the structures in the veebral canal. REF.CUNNINGHAM'S MANUAL OF PRACTICAL ANATOMY,Vol.3,PG.193", "cop": 1, "opa": "Areolar tissue and internal veebral venous plex uses", "opb": "Only areolar tissue", "opc": "Only cerebrospinal fluid", "opd": "Veebral venous plexus and cerebrospinal fluid", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "00e5f19a-b3e1-4d49-9468-d30ea7aba357", "choice_type": "single"} {"question": "Superficial inguinal ring is deficient of", "exp": "It is a triangular opening that forms the exit of the inguinal canal, which houses the ilioinguinal nerve, the genital branch of the genitofemoral nerve, and the spermatic cord (in men) or the round ligament (in women). At the other end of the canal, the deep inguinal ring forms the entrance. ref - BDC 6e vol2", "cop": 3, "opa": "External oblique abdominis", "opb": "Internal oblique abdominis", "opc": "External oblique aponeurosis", "opd": "Internal oblique aponeurosis", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c8fa80ed-9153-4b26-93a2-5d730b16f96b", "choice_type": "single"} {"question": "Vitamin k associated clotting factors are", "exp": "Ref Robbins 8/e 118-119 ; 9/e p 119 Physiologic Effects of Vitamin K Vitamin K serves as an essential cofactor for a carboxylase that catalyzes carboxylation of glutamic acid residues on vitamin K-dependent proteins. The key vitamin K-dependent proteins include: Coagulationproteins: factors II (prothrombin), VII, IX and X.", "cop": 1, "opa": "9,10", "opb": "1,5", "opc": "7,8", "opd": "1,81", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "301be874-e1b4-469c-89ee-f44aa1fee33b", "choice_type": "single"} {"question": "Infraclavicular lesion of tuberculosis is known as", "exp": "refer robins page no 370 Hematogenous spread to apex of upper lobe resulting in a post primary infective lesion which heals with scarring is known as \"Simon's focus.\" ... \"Puhl's lesion/nodule\" is the term for isolated lesion of chronic pulmonary TB in the apex of the lung.", "cop": 3, "opa": "Gohns focus", "opb": "Puhls focus", "opc": "Assmans focus", "opd": "Simmons focus", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "37e17d4b-5e4d-4c6f-9282-b34539f6dd15", "choice_type": "single"} {"question": "In contrast to heparin, enoxaparin", "exp": "Ref: KDT 6/e p599 Enoxaparin is a LMW heparin. It does not require monitoring Both heparin as well as enoxaparin do not crose placenta and are not teratogenic.", "cop": 1, "opa": "Can be used without monitoring the patients aPTT", "opb": "Is less likely to have a teratogenic effect", "opc": "Is more likely to be given intravenously", "opd": "Is more likely to cause thrombosis and thrombocytopenia", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "5f9d694e-a4a6-48fa-bc21-a826dcd16128", "choice_type": "single"} {"question": "Most pathognomic sign of irreversible cell injury", "exp": "Ref Robbins 9/e p50 Mitochondrial Damage and Dysfunction Mitochondria may be viewed as \"mini-factories\" that produce life-sustaining energy in the form of ATP. Not surprisingly, therefore, they are also critical players in cell injury and death (Fig. 1-16). Mitochondria are sensitive to many types of injurious stimuli, including hypoxia, chemi- cal toxins, and radiation. Mitochondrial damage may result in several biochemical abnormalities: * Failure of oxidative phosphorylation leads to progres- sive depletion of ATP, culminating in necrosis of the cell, as described earlier. * Abnormal oxidative phosphorylation also leads to the formation of reactive oxygen species, which have many deleterious effects, described below. * Damage to mitochondria is often associated with the formation of a high-conductance channel in the mito- chondrial membrane, called the mitochondrial permea- bility transition pore. The opening of this channel leads to the loss of mitochondrial membrane potentialand pH changes, fuher compromising oxidative phosphorylation. * The mitochondria also contain several proteins that, when released into the cytoplasm, tell the cell there is internal injury and activate a pathway of apoptosis, dis- cussed later.", "cop": 1, "opa": "Amorphous densities in mitochondria", "opb": "Swelling of the cell membrane", "opc": "Ribosomes detached from endoplasmic reticulum", "opd": "Clumping of nuclear chromatin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3b4f1a3d-294e-4408-bf8e-0c931c1d17ec", "choice_type": "single"} {"question": "Most Baroreceptors and chemoreceptors are situated in", "exp": "Most Baroreceptors and chemoreceptors are situated in left auricle.", "cop": 3, "opa": "Infundibulum of Right Ventricle", "opb": "Crista terminalis", "opc": "left auricle", "opd": "Infundibulum of left Ventricle", "subject_name": "Anatomy", "topic_name": null, "id": "2c446535-7bae-4dfb-954d-3170054c7e4d", "choice_type": "single"} {"question": "Most potential route for spread of infection from CNS to inner ear", "exp": "Cochlear aqueduct is most potential route for spread of infection from CNS to inner earQ Cochlear aqueduct & vestibular aqueduct are 2 bony channels (canals) that connect inner ear (cochlea & vestibule respectively) to intracranial sub arachnoid space. Vestibular aqueduct contains endolymphatic duct filled with endolymph, which does not communicate freely with CSF as it ends in a cul de sac and forms a closed space. Whereas perilymph filled cochlear aqueduct is in direct continuation with the CSF which makes it a most potential route of infection. Hyle's fissure is present in early embryonic life that normally obliterates by 24 weeks of gestation. When persistent it provides a connection from middle ear to subarachnoid space.", "cop": 2, "opa": "Vestibular aqueduct", "opb": "Cochlear aqueduct", "opc": "Endolymphatic sac", "opd": "Hyle fissure", "subject_name": "Anatomy", "topic_name": null, "id": "6939f04e-4b7b-4c32-ab48-81dd332435cd", "choice_type": "single"} {"question": "Dye used in IV cholangiography is", "exp": "Iponoic acid is used in oral cholecystography Biligraffin is used in IV cholangiography Ref: Sabiston 20th edition Pgno :1487", "cop": 3, "opa": "Conray", "opb": "Diansoil", "opc": "Biligraffin", "opd": "Myodil", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e6bfc475-24c2-43cb-8e2f-a7adbcb1a1b6", "choice_type": "single"} {"question": "Most commonly injured muscle in Rotator cuff injury is", "exp": null, "cop": 3, "opa": "Infraspinatus", "opb": "Subscapularis", "opc": "Supraspinatus", "opd": "Teres minor", "subject_name": "Anatomy", "topic_name": null, "id": "4e4d5412-0071-4c22-9a73-1ef90ecee3e2", "choice_type": "single"} {"question": "Cullen's sign is seen in", "exp": "Signs indicative of retroperitoneal bleeding in severe pancreatitis Flank ecchymosis - Grey Turner sign Periumbilical ecchymosis- Cullen's sign Inguinal ecchymosis - Fox sign Ref: Sabiston 20th edition Pgno : 1527", "cop": 3, "opa": "Acute cholecystitis", "opb": "Acute pancreatitis", "opc": "Acute hemorrhagic pancreatitis", "opd": "Blunt injury abdomen", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d8a1a0b3-84f0-4e15-8a7b-bc2a8a43c540", "choice_type": "single"} {"question": "Strain used in Mumps vaccine", "exp": "Strains in Mumps Jeryll Lynn strain RIT 4385 Leningrad 3 strain L-Zagren strain Urabe strain Rubini strain Strains in Measles Edmonston-Zagreb strain Schwatz strain Moraten strain", "cop": 2, "opa": "Oka", "opb": "Jeryl Lynn", "opc": "Danish 1331", "opd": "Edmonston Zagreb", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "444a246f-0e49-4932-97a4-9181b30cb099", "choice_type": "single"} {"question": "STYLOHYOID muscle is supplied by", "exp": "Stylohyoid is a small muscle supplied by the facial nerve. The action of stylohyoid is to pull the hyoid bone upwards and backwards, and with other hyoid muscles, it also fixes the hyoid bone. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 1, "opa": "Facial", "opb": "Glossopharyngeal", "opc": "Ansa cervical", "opd": "Vagus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1f9a7c65-7ec4-4a56-a8f6-7ebd2c8c2ada", "choice_type": "single"} {"question": "Patient a known case off alcohol dependence after 12 to 18 hrs of last drink develops seizure for the first time in his life.possible diagnosis is", "exp": "withdrawl symptoms are present due to alcohol withdrawl based on the time duration between the last drink and the presentation of symtoms withdrawls symptoms can be classified into many types it may be mild symptoms like tremore to seizure to life threatening symptoms like delirium tremens ref.Kaplon and Sadock, synopsis of Psychiatry, 11 th edition, pg no.625", "cop": 3, "opa": "Delirium tremens", "opb": "seizure disorder", "opc": "Rum fits", "opd": "wernickes encephalopathy", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "7a1cd5a6-4171-47b0-8fa6-c233de573a1b", "choice_type": "single"} {"question": "Place of first liver transplant", "exp": "Firat liver transplantation was done by Starzl in 1963, in Denver, University of Colorado Ref: Sabiston 20th edition Pgno : 637", "cop": 3, "opa": "Pittsburgh", "opb": "Boston", "opc": "Colarado", "opd": "Cambridge", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b13fa286-89a0-4c38-b4b8-ff08763bf375", "choice_type": "single"} {"question": "The most common secondary malignancy in a patient having retinoblastoma is", "exp": "Ref Robbins 9/e p293 Retinoblastoma is the most common primary intraocular malignancy of children . involvement of both eyes with pineal gland gland is called as trilateral retinoblastoma The pinealoblastoma in association with retinoblastoma is a primary tumor In approximately 40% of cases, retinoblastoma occurs in individuals who inherit a germ line mutation of one RB alleles .This variant of retinoblastoma is inherited as an autosomal dominant trait and is associated with osteosarcoma . Osteosarcoma is therefore the commonest secondary malignancy associated with retinoblastoma", "cop": 1, "opa": "Osteosarcoma", "opb": "Renal cell carcinoma", "opc": "Pineoblastoma", "opd": "Osteoblastoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cee46a79-3747-41f0-abe3-e0d59e685164", "choice_type": "single"} {"question": "The infectivity of a convalescent case of cholera lasts for", "exp": "Preclinical or incubatory carrier -The incubatory carriers are potent carriers (1-5 days)Convalescent carrier - Patient who has recovered from an attack of cholera may continue to excrete vibrios, during his convalescence for 2 -3 weeksContact or healthy carrier - Subclinical infection contracted through association with a source of infection. Duration < 10 days.Chronic carrier - Over 10 years(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 244)", "cop": 3, "opa": "Less than 7 days", "opb": "7-14 days", "opc": "14-21 days", "opd": "21-28 days", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "4b520350-a915-453c-ba44-a67afa924174", "choice_type": "single"} {"question": "Abductors of vocal cord is", "exp": "i.e. (Posterior cricoarytenoids): (243-BDC-3-5th ed)Muscles acting on the Larynx|| |Movements Muscles1. Elevation of larynx Thyrohyoid, mylohyoid2. Depression of larynx Sternothyroid, sternohyoid3. Opening of larynx Thyroepiglotticus4. Closing inlet of larynx Aryepiglotticus5. Abductor of vocal cords Posterior cricoaryteroids only6. Adductor of vocal cords Lateral cricoarytenoids, transverse oblique arytenoids7. Tensor of vocal cords Cricothyroids8. Relaxor of vocal cords Thyroarytenoids(i) Cricothyroid is supplied by external laryngeal nerve(ii) Rest of the intrinsic muscle - recurrent laryngeal nerve", "cop": 2, "opa": "Lateral cricoarytenoids", "opb": "Posterior cricoarytenoids", "opc": "Thyro arytenoids", "opd": "Cricothyroids", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "02068b30-0938-4aff-b0e6-c49ad9818c8b", "choice_type": "single"} {"question": "If a drug is active against pre erythrocytic stage of the malaria parasite it will be useful as", "exp": "(Ref KDT 6/e p782) Stage ---clinical use Preerythrocytic- Causal prophylaxis Erythrocytic-Clinical cure -Suppressive prophylaxis Exo-Erythrocytic: Radical cure Gametocytic Pevention of transmission", "cop": 2, "opa": "Suppressive prophylactic", "opb": "Causal prophylactic", "opc": "Clinical curative", "opd": "Radical curative", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "c7a654a2-8e55-4bd5-8560-65da0139a3b6", "choice_type": "single"} {"question": "Drug of choice for cardiogenic shock is", "exp": "Dobutamine and dopamine are inotropic agents used in CCF and cardiac shock but dobutamine is best as it doesn't interfere with alpha receptors producing Vaso contriction.", "cop": 2, "opa": "Dopamine", "opb": "Dobutamine", "opc": "Droxidopa", "opd": "Nor adrenaline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5c7d34dc-9272-4c26-a8d0-dc8a52085d4b", "choice_type": "single"} {"question": "Most dependent Bronchopulmonary segment in supine position is", "exp": "Most dependent Bronchopulmonary segment in supine position is Right Superior segment.", "cop": 2, "opa": "Left Superior segment", "opb": "Right Superior segment", "opc": "Right posterior basal segment", "opd": "Left posterior basal segment", "subject_name": "Anatomy", "topic_name": null, "id": "52ea0f2d-e607-4605-99b0-f9f25795e169", "choice_type": "single"} {"question": "Superior pancreaticoduodenal artery is a branch of", "exp": "(Gastroduodenal artery) (263-BDC-2 4th) (261-Snell 7th)* Superior pancreatico duodenal artery is a branch of Gastroduodenal artery* Inferior pancreatico duodenal artery is a branch of superior mesenteric arteryHEPATIC ARTERY - branchesSUPERIOR MESENTERIC ARTERY branches* Right gastric artery* Gastroduodenal artery-*Right gastroepiploic-*Superior pancreatico duodenal* Right and left hepatic arteries (Right hepatic artery gives off cystic artery)* *Left gastroepiploic artery is branch of splenic artery* *Inferior pancreatico duodenal artery* Middle colic artery* Iliocolic artery (Appendicular artery is a branch of the posterior cecal artery)* Jejunal and Ileal branches", "cop": 2, "opa": "Splenic artery", "opb": "Gastroduodenal artery", "opc": "Right gastric artery", "opd": "Superior mesenteric artery", "subject_name": "Anatomy", "topic_name": "Abdomen & Pelvis", "id": "1e08c875-5710-4922-953c-f9d59b0a6f34", "choice_type": "single"} {"question": "Nerve supply of obturator internus is by", "exp": "OBTURATOR INTERNUS Fan-shaped Belly lies in pelvis and tendon in gluteal region.Action: lateral rotators of thigh at hip joint.supplied by nerve to obturator internus.Root value: L5,S1,S2Branches: obturator internus and superior gamellus.{Reference: BDC 6E page no.173}", "cop": 3, "opa": "L1-L3", "opb": "L4-S1", "opc": "L5-S2", "opd": "S1-S3", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d6b597c1-ad9a-4194-9dbd-e2965109a12f", "choice_type": "single"} {"question": "Grey Turner's sign (Flank discolouration) is seen in", "exp": "Signs indicative of retroperitoneal bleeding in severe pancreatitis Flank ecchymosis - Grey Turner sign Periumbilical ecchymosis- Cullen's sign Inguinal ecchymosis - Fox sign Ref: Sabiston 20th edition Pgno : 1527", "cop": 3, "opa": "Acute pyelonephritis", "opb": "Acute cholecystitis", "opc": "Acute pancreatitis", "opd": "Acute peritonitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2e99fa14-499d-4a04-8a72-3584961ae920", "choice_type": "single"} {"question": "Pruritus precedes jaundice in", "exp": "Primary biliary cirrhosis Believed to be an autoimmune etiology, leading to progressive destruction of intrahepatic bile ducts More common in females Associated with autoimmune disorders (CREST, Sicca syndrome, Autoimmune thyroiditis, Renal tubular acidosis) Clinical features Most patients are asymptomatic, pruritus the commonest and earliest symptom. Pruritus precedes jaundice in PBC, Pruritus is most bothersome in evening Jaundice, fatigue, melanosis (gradual darkening of exposed areas of skin), deficiency of aft soluble vitamins due to malabsorption Xanthomas and xanthelesmas due to protracted elevation of serum lipids Ref: Sabiston 20th edition Pgno : 639", "cop": 1, "opa": "Primary biliary cirrhosis", "opb": "Secondary biliary cirrhosis", "opc": "Primary sclerosing cholangitis", "opd": "CBD stone", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e3fa7c77-8455-46ec-8b5f-64a206e20a86", "choice_type": "single"} {"question": "Lateral Sacral artery is a branch of", "exp": "Lateral Sacral artery is a branch of Posterior division of Internal Iliac artery. Other branches of Posterior division of Internal Iliac artery are\n\nSuperior gluteal Artery\nIliolumbar artery", "cop": 2, "opa": "Anterior division of Internal Iliac artery", "opb": "Posterior division of Internal Iliac artery", "opc": "External Iliac artery", "opd": "Direct branch from Common Iliac artery", "subject_name": "Anatomy", "topic_name": null, "id": "5264a271-c14c-45b9-be59-4ee744bfb892", "choice_type": "single"} {"question": "In cerebellar lesion NOT seen is", "exp": "Resting tremor is the manifestation of parkinsonism In cerebellar lesion intentional tremors are seen", "cop": 3, "opa": "Ataxia", "opb": "Nystagmus", "opc": "Resting tremors", "opd": "Past pointing", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "4034edd7-030e-4e74-a67b-f01c752e5fbf", "choice_type": "single"} {"question": "Posterior relation of neck of pancreas", "exp": "The frontal vein (supratrochlear vein) begins on the forehead in a venous plexus which communicates with the frontal branches of the superficial temporal vein. The veins converge to form a single trunk, which runs downward near the middle line of the forehead parallel with the vein of the opposite side. The two veins are joined, at the root of the nose, by a transverse branch, called the nasal arch, which receives some small veins from the dorsum of the nose. At the root of the nose the veins diverge, and, each at the medial angle of the orbit, joins the supraorbital vein, to form the angular vein. Ref - BDC 6e vol2 pg 298-300", "cop": 2, "opa": "IVC", "opb": "Origin of porntal vein", "opc": "Aoa", "opd": "Common bile duct", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "1d10dbc8-5850-4c91-bb7c-ae33530f0673", "choice_type": "single"} {"question": "Abduction of shoulder is initiated by", "exp": "Abduction of shoulder - abduction and adduction take place at right angles to the plane of flexion and extension , i. e., approximately midway between the sagittal and coronal planes. In abduction , the arm moves anterolaterally away from the trunk. This movement is in the same plane as that of the body of the scapula. Muscles bringing about movements at the shoulder joint - (i)Both Supraspinatus and Deltoid muscles initiate abduction and are involved throughout the range of abduction from 0 - 90 digrees. (ii)Serratus anterior 90 - 180 digrees (iii) Upper and lower fibres of trapezius 90 - 180 digrees. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1, pg. no., 149.", "cop": 1, "opa": "Supraspinatus", "opb": "Trapezius", "opc": "Serratus anterior", "opd": "Levator scapulae", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "50e008ac-77f0-4301-8006-4c3c0b0df39e", "choice_type": "single"} {"question": "At 30 days intra uterine life", "exp": "(D) Pinna appears # Development of External Ear:> Auricle, or pinna, is formed from about six mesodermal thickenings (called tubercles or hillocks) that appear on the Mandibular (First) & Hyoid (Second) arches, around the opening of the dorsal part of the first ectodermal cleft (i.e. around the opening of the external acoustic meatus).> External acoustic meatus is derived from the dorsal part of the first ectodermal cleft.> Mandibular arch forms only tragus & a small area around it, rest of the auricle being formed from the Hyoid arch.", "cop": 4, "opa": "Heart starts beating", "opb": "Cerebellum develops", "opc": "Optical vesicle appears", "opd": "Pinna appears", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "3a548dfa-d988-44b5-9e66-3057cbe368c9", "choice_type": "single"} {"question": "The poly ahritic condition that is not common inm", "exp": "Ref Robbins 9/e p218 Similar to many autoimmune disease ,SLE predominantly affects women.a female to male ratio of 9:1.is seen during the reproductive age get .female to male ratio is only 2:1 for the development of the disease at childhood or at the age of 65", "cop": 4, "opa": "Gout", "opb": "Psoriasis ahritis", "opc": "Ankylosing spondylitis", "opd": "SLE", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4ba2c8a8-f615-4ce6-8563-a06dfe393b9c", "choice_type": "single"} {"question": "CCA can be palpated at", "exp": null, "cop": 1, "opa": "Thyroid cartilage.", "opb": "1st tracheal ring.", "opc": "Cricoid cartilage.", "opd": "Arteries can never be palpated.", "subject_name": "Anatomy", "topic_name": null, "id": "e0a9dd85-0cdb-490f-bde7-b2b43984221c", "choice_type": "single"} {"question": "Lymph flow from the foot is", "exp": "B i.e. Increased by massaging the footFoot massage increases the rate of lymph flow by causing intermittent external compression of lymphatic vessels, which promotes pumping of lymph.", "cop": 2, "opa": "Increased when an individual rises from the supine to standing position", "opb": "Increased by massaging the foot", "opc": "Increased when capillary permeability is decreased", "opd": "Decreased when the valves of the leg veins are incompetnet", "subject_name": "Anatomy", "topic_name": null, "id": "c1705fde-e966-4fb7-bd38-c53d19dd4962", "choice_type": "single"} {"question": "Presence of an ossification centre in talus means that", "exp": "Centre comes at 7 months of intrauterine life, ble", "cop": 2, "opa": "The foetus is full term", "opb": "The foetus is ble", "opc": "The foetus was live born", "opd": "The foetus was still born", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9c466b13-6909-4b9f-8574-3d5312a89b45", "choice_type": "single"} {"question": "Referred pain in external hemorrhoids is due to", "exp": "Internal hemorrhoids are located on the inside lining of the rectum and cannot be felt unless they prolapse and push through the anus opening causing pain and itching. A thrombosed external hemorrhoid occurs when blood within the blood vessel clots, and may cause significant pain and swelling.", "cop": 2, "opa": "Common pudendal nerve", "opb": "Inferior rectal nerve", "opc": "Splanchnic nerve", "opd": "Sympathetic nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "be8f1b99-b269-4e79-b24e-fa66c697752c", "choice_type": "single"} {"question": "The most common mode of transmission of brucella is", "exp": "The organism from the infected animal enters the human body by direct contact. Through the wound, the conjunctiva, by inhalation or by ingestion of products from infected animals. The incubation period is usually about 10-30 days, but may sometimes be very prolonged. Ref: Textbook of microbiology; Ananthanarayana and paniker's; 10th edition; Pg: 346", "cop": 1, "opa": "Direct contact", "opb": "Ingestion of raw milk", "opc": "Air borne", "opd": "Man to man", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "599ecd5d-e095-45db-8674-2391eba542e9", "choice_type": "single"} {"question": "NARP syndrome is seen in", "exp": "NARP syndrome (neuropathy ,ataxia, & retinitis pigmentosa) is a condition related to changes in mitochondrial DNA Refer Harrison 17/316-317 Robbins 8/1328", "cop": 1, "opa": "A. Mitochondrial diseases", "opb": "B. Glycogen storage diseases", "opc": "C. Lysosomal storage diseases", "opd": "D. Lipid storage diseases", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ba013b0-d7d2-4620-b17d-e236eff2bbd1", "choice_type": "single"} {"question": "Special visceral efferent DOES NOT involve", "exp": "(D) Dorsal nucleus of X cranial nerveNUCLEI BELONGING TO COLUMNSGSEOculomotor, Trochlear, Abducent, Hypoglossal nucleiSVEMotor nucleus of V nerve Motor nucleus of VII nerve Nucleus AmbiguusGVEEW nucleus, Lacrimatory nucleus, Superior & Inferior salivatory nuclei, Dorsal vagal nucleusGVA/SVANucleus of Tractus solitariusGSASpinal, Principal sensory & Mesencephalic nuclei of V nerveSSAVestibular & Cochlear nuclei[?]III-Special Visceral (Branchial)Efferent (SVE) Column:Motor nuclei which supply musclesdeveloped from the pharyngeal arches, (Branchiomotor cell column).These are (5,7,9 & 10)Ambiguus nucleus, in Medulla (9,10 & cranial part of Accessory nerve)Motor Nucleus of the Trigeminal nerve, in the Mid pons.Motor nucleus of the Facial nerve in the Caudal pons.CRANIAL NERVE FUNCTIONAL COMPONENTSFunctional componentAbbreviation General FunctionCranial nerves containing componentGeneral somatic afferentGSAPerception of touch, pain, temperatureTrigeminal nerve (V); Facial nerve (VII); Vagus nerve (X)General visceral afferentGVASensory input from visceraGlossopharyngeal nerve (IX); Vagus nerve (X)Special afferentSASmell, taste, vision, hearing & balanceOlfactory nerve (1); Optic nerve (II); Facial nerve (VII); Vestibulocochlear nerve (VIII); Glossopharyngeal nerve (IX), Vagus nerve (X)General somatic efferentGSEMotor innervation to skeletal (voluntary) musclesOculomotor nerve (II); Trochlear nerve (IV); Abducent nerve (VI); Hypoglossal nsrve (XII)General visceral efferentGVEMotor innervation to smooth muscle, heart muscle & glandsOculomotor nerve (III); Facial nerve (VI); Glossopharyngeal nerve (IX); Vagus nerve (X)Branchial efferent**BEMotor innervation to skeletal muscles derived from pharyngeal arch mesodermTrigeminal nerve (V); Facial nerve (VII), Glossopharyngeal nerve (IX); Vagus nerve (X); Accessory nerve (XI)* Special sensory or Special Visceral Afferent (SVA) - smell, taste; special somatic afferent (SSA) - vision, hearing, balance.** Special Visceral Efferent (SVE) or branchial motor.Other Option[?]Nucleus AmbiguusRuns in a rostral to caudal direction in the medulla & is located in the ventrolateral reticular formation, posterior to the inferior olivary nuclear complex and anteromedial to the spinal trigeminal nucleus.[?]Dorsal nucleus of the Vagus nerve (or Posterior motor nucleus of Vagus)Is a cranial nerve nucleus for the vagus nerve in the medulla that lies ventral to the floor of the fourth ventricle.It mostly serves parasympathetic vagal functions in the gastrointestinal tract, lungs, and other thoracic and abdominal vagal innervations.The cell bodies for the preganglionic parasympathetic vagal neurons that innervate the heart reside in the nucleus ambiguus.Additional cell bodies are found in the nucleus ambiguus, which give rise to the branchial efferent motor fibers of the vagus nerve (CN X) terminating in the laryngeal, pharyngeal muscles & musculus uvulae.", "cop": 4, "opa": "Nucleus ambiguus", "opb": "Motor nucleus of V cranial nerve", "opc": "Motor nucleus of VII cranial nerve", "opd": "Dorsal nucleus of X cranial nerve", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "63fe1814-a414-4c20-8f21-03d23f0fefef", "choice_type": "single"} {"question": "The sensitivity of casoni's test is", "exp": "The sensitivity of casoni's test ranges from 55-65%", "cop": 2, "opa": "50%", "opb": "60%", "opc": "75%", "opd": "90%", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ca8af5fd-a91d-465d-85eb-f2cf897c242b", "choice_type": "single"} {"question": "Adductor pollicis is supplied by", "exp": "Deep branch of ulnar nerve supplies the palmaris brevis muscle and muscles of hypothenar eminence , medial two lumbricals , 4-1 dorsal interossei muscles and 4-1 palmar interossei . B D Chaurasia 7th edition Page no : 182", "cop": 2, "opa": "Superficial branch of ulnar nerve", "opb": "Deep branch of ulnar nerve", "opc": "Superficial branch of median nerve", "opd": "Deep branch of median nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e2cafba6-caa1-4455-956e-10880410922e", "choice_type": "single"} {"question": "Double aoa occurs due to", "exp": "Double aoa occurs due to the persistence of distal poion of the right dorsal aoaRef: Inderbir Singh&;s Human embryology; Tenth edition; Pg 257", "cop": 4, "opa": "Non development of the right 4th aoic arch", "opb": "Non development of the left 4th aoic arch", "opc": "Non division of truncus aeriosus", "opd": "Persistence of distal poion of the right dorsal aoa", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "47cd50c8-c18d-4d96-9cc4-86da5b7af58d", "choice_type": "single"} {"question": "Umbilical aery is a branch of", "exp": "Anterior division of internal iliac aeryA pa of Umbilical aery persists as superior vesical aery and remaining aery becomes obliterated forming medial umbilical ligament.", "cop": 3, "opa": "Coeliac aery", "opb": "Superior mesenteric aery", "opc": "Anterior division of internal iliac aery", "opd": "Posterior division of internal iliac aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ae089b5b-42c2-4fd8-92eb-6dfbd02faaa0", "choice_type": "single"} {"question": "4th Ventricle develops from", "exp": "Inderbir Singh&;s Human embryology Tenth edition Pg 321 The cavity of mesencephalon remains narrow and forms the aqueduct while the cavity of rhombencephalon forms the fouh ventricle", "cop": 4, "opa": "Telencerphalon", "opb": "Mesencephalon", "opc": "Diecephalon", "opd": "Rhombencephlon", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b3771386-9220-42ca-860c-b47d8990dcc7", "choice_type": "single"} {"question": "Blood supply of great toe is", "exp": "The great toe is supplied by the first dorsal metatarsal aery the dorsalis pedis aery and plantar digital aery the medial plantar aery. Ref: Gray's 40e/p-1364", "cop": 1, "opa": "Dorsalis pedis aery", "opb": "Lateral plantar aery", "opc": "Metacarpal aery", "opd": "Posterioibial aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a1c6ce87-e9ec-46e9-8334-0baca0aeb2ab", "choice_type": "single"} {"question": "Maximum AP diameter of trachea in male and female are", "exp": "Trachea: - Trachea is a flexible tube that extends from veebral level C6 in the lower neck to veebral level T 4 / 5 in the mediastinum where it bifurcates into a right and a left main bronchus. Measurement of trachea: - Parameters Average Minimum Maximum A - P diameter (mm) Male Female Male Female Male Female 18.82 13.25 10.15 10.72 22.92 17.25 Transverse diameter 16.30 14.92 11.02 10.57 19.98 17.22", "cop": 4, "opa": "27 mm and 25 mm", "opb": "25 mm and 23 mm", "opc": "25 mm and 21 mm", "opd": "20 mm and 15 mm", "subject_name": "Anatomy", "topic_name": "Pharynx, larynx and trachea and cranial nerves 3,4,6", "id": "36af1fd9-9ae7-4744-9330-49870ab566f0", "choice_type": "single"} {"question": "0", "exp": "0", "cop": 1, "opa": "0", "opb": "0", "opc": "0", "opd": "0", "subject_name": "Anatomy", "topic_name": null, "id": "c16e7d55-906e-4f09-baf2-35397fd4a852", "choice_type": "single"} {"question": "Sistrunk operation is used for", "exp": "ThyroglossalDuct Cyst A thyroglossal duct cyst is a midline neck lesion that originates at the base of the tongue at the foramen cecum and descends through the central poion of the hyoid bone. Although thyroglossal duct cysts may occur anywhere from the base of the tongue to the thyroid gland, most are found at or just below the hyoid bone . A thyroid diveiculum develops as a median endodermal thickening at the foramen cecum in the embryonic stage of development. The thyroid diveiculum descends in the neck and remains attached to the base of the tongue by the thyroglossal duct. Also, as the thyroid gland descends to its normal pretracheal position, the ventral cailages of the second and third branchial arches form the hyoid bone--hence the intimate anatomic relationship of the thyroglossal duct remnant with the central poionof the hyoid bone. The thyroglossal duct normally regresses by the time the thyroid gland reaches its final position. When the elements of the duct persist despite complete thyroid descent, a thyroglossal duct cyst may develop. Failure of normal caudal migration of the thyroid gland results in a lingual thyroid, in which no other thyroid tissue is present in the neck. Ultrasound or radionuclide imaging may provide useful information to identify the presence of an ectopic thyroid gland in the neck. The standard operation for thyroglossal duct cysts has remained unchanged since it was described by Sistrunk in 1928, which involves complete excision of the cyst in continuity with its tract, the central poion of the hyoid bone, and the tract interior to the hyoid bone extending to the base of the tongue Failure to remove these tissues entirely will likely result in recur- rence because multiple sinuses have been histologically identified in these locations. Ref: Sabiston 20th edition Pgno: 1861", "cop": 1, "opa": "Thyroglossal cyst", "opb": "Branchial cyst", "opc": "Cystic hygroma", "opd": "Laryngocele", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "859e1f68-6995-46c2-abdd-49a33611ab28", "choice_type": "single"} {"question": "In cholecytectomy of cirrhotic patient , fresh frozen plasma should be given", "exp": "A cirrhotic patient with abnormal coagulation who needs cholecystectomy should be given FFP FRESH FROZEN PLASMA Transfusions with FFP are given to replenish clotting factors The effectiveness of the transfusion in maintaining hemostasis is dependent on the quantity of each factor delivered and its half life The half-life on the most stable clotting factor, FACTOR-VII, is 4 to 6 hours A reasonable transfusion scheme would be to give FFP on call to the operating room. This way the transfusion is complete prior to the incision, with circulating factors to cover the operative and immediate post-op period Ref: Sabiston 20th edition Pgno :1496", "cop": 1, "opa": "Just before operation", "opb": "At the time of operation", "opc": "6 hours before operation", "opd": "12 hours after operation", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "365863fb-0dfa-4148-8db6-00bb7ed0f1a2", "choice_type": "single"} {"question": "Boa's sign seen in", "exp": "Boas' or Boas's sign is hyperaesthesia (increased or altered sensitivity) below the right scapula is a symptom of acute cholecystitis", "cop": 2, "opa": "Acute cholangitis", "opb": "Acute Cholecystitis", "opc": "Mirizzi syndrome", "opd": "Primary sclerosing cholangitis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "85ecbde6-8985-4831-9a62-2938ff9187c8", "choice_type": "single"} {"question": "Popcorn calcification in mammography is seen in", "exp": "Pattern of calcification in breast diseases Carcinoma--Microcalcification, punctuate, branching Fibro adenoma - Popcorn( coarse, granular, crushed Stone) Fibrocystic disease - powdery Fat necrosis - Curvilinear Ref: Robbins 9th edition Pg no : 1069", "cop": 1, "opa": "Fibro adenoma", "opb": "Fat necrosis", "opc": "Cystosarcoma phyllodes", "opd": "CA breast", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "011b871f-568c-42e6-ab00-f9b99ac03d62", "choice_type": "single"} {"question": "Rider's bones are ossification of", "exp": "Rider's bone develops in the tendon of adductor longus in professional riders. It is a sesamoid bone.that has no periosteum and ossifies after bih. Reference: BD Chaurasia's handbook of general anatomy, 5th edition, pg 55", "cop": 2, "opa": "Adductor brevis", "opb": "Adductor longus", "opc": "Adductor magnus", "opd": "Flexor digitorum superficialis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "74a91165-dea5-4b35-bfe5-ba2ce5e33ea0", "choice_type": "single"} {"question": "The deep ring is situated in", "exp": "INGUINAL CANAL:-\nThe oblique intermuscular passage in the lower part of the anterior abdominal wall.\nExtends from the deep inguinal ring to superficial.\nDeep ring- oval opening in fascia transversalis.\n 1.25 cm above mid-inguinal point.\nSuperficial ring: triangular gap in external oblique aponeurosis.\nLength: 4cm\nDirected downwards forwards and medially.", "cop": 3, "opa": "External oblique", "opb": "Internal oblique", "opc": "Fascialis tranversalis", "opd": "Cremasteric fascia", "subject_name": "Anatomy", "topic_name": null, "id": "1d7f0b25-6249-410d-a6ad-fb4092f7c8b9", "choice_type": "single"} {"question": "Patent foramen ovale is due to", "exp": "The primitive atrium is divided into left and right atria by an interatrial septum which is formed by fusion of septum primum and septum secundum. The sequence of events are as follows\n\nSeptum primum arises from the roof of the common atrium (primitive atrium) and grows caudally towards septum intermedium (fused AV cushions).\nForamen primum is formed between the free border of growing septum primum and fused AV cushions (septum intermedium).\nShortly afterwards the septum primum fuses with septum intermedium (fused AV cushions), obliterating foramen primum\nForamen secundum is formed by degeneration of cranial part of septum primum.\nSeptum secundum grows caudally to the right of septum primum and overlaps the foramen secundum. The passage between septum primum and septum secundum is called foramen ovale. After birth, foramen ovale closes by fusion of septum primum with septum secundum. Failure of fusion of these two septa results in patent foramen ovale.", "cop": 4, "opa": "Failure of closure of sinoatrial orifice", "opb": "Failure of fusion of septum primum and endocardial cushion", "opc": "Failure of fusion of septum primum and septum intermedium", "opd": "Failure of fusion of septum primum and septum secondum", "subject_name": "Anatomy", "topic_name": null, "id": "f052dd00-fde8-45f9-bbdf-85b45eff31c5", "choice_type": "single"} {"question": "APUD cells are seen in", "exp": "Anime Precursor Uptake and Decarboxylation(APUD) cells are also known as neuroendocrine cells.These cells are the cell of origin of the carcinoid tumor Ref Robbing 9/e p719", "cop": 2, "opa": "Bronchial adenoma", "opb": "Bronchial carcinoid", "opc": "Hepatic adenoma", "opd": "Villous adenoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9676de6a-2968-4368-a717-2be77d3bf161", "choice_type": "single"} {"question": "Obturator nerve enters thigh at", "exp": "It descends through the fibers of the psoas major, and emerges from its medial border near the brim of pelvis; it then passes behind the common illaic aery and on the lateral side of the internal illiac aery and ureter, and runs along the lateral wall of the lesser pelvis, above and in front of the obturator vessel, to the upper pa of the obturator foramen. Here it enters the thigh, through the obturator canal, and divides into an anterior and a posterior branch, which are separated at first by some of the fibers of the obturator externus, and lower down by the adductor brevis. ref -sciencedirect.com", "cop": 2, "opa": "Adductor canal", "opb": "Obturator canal", "opc": "Superficial inguinal ring", "opd": "Femoral canal", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "09c632c3-fd1a-4feb-9a7b-ba6acc89d0a1", "choice_type": "single"} {"question": "The palatine tonsil", "exp": "Palatine tonsil lies on superior constrictor muscle. It drains into deep cervical nodes particularly jugulodigastric nodes. It is innervated by glossopharyngeal nerve .", "cop": 3, "opa": "Lies on the middle constrictor muscle", "opb": "Drains into submandibular lymph nodes", "opc": "Is supplied by facial artery", "opd": "Is innervated by pharyngeal plexus", "subject_name": "Anatomy", "topic_name": null, "id": "5b81a787-548f-40dd-b367-56fec81f52a6", "choice_type": "single"} {"question": "Nerve commonly involved in fracture distal shaft of the humerus", "exp": "Radial nerve is the most commonly injured nerve in fracture shaft humerus It is paicularly common in oblique fracture at junction of middle and distal third bone", "cop": 1, "opa": "Radial nerve", "opb": "Medial", "opc": "Ulnar", "opd": "Circumflex Brachial nerve", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "946554bb-bd59-483a-b17a-bbe2428c65df", "choice_type": "single"} {"question": "Brodmann Area no. constitutes Wernicke’s area of speech", "exp": "Wernicke’s area is sensory speech centre of brain. It is constituted by area no 22-auditory association area.\nArea no 39-angular gyrus and Area no 40-supramarginal gyrus.", "cop": 4, "opa": "41, 42, 22", "opb": "22, 42, 39", "opc": "42, 41, 44", "opd": "22, 39, 40", "subject_name": "Anatomy", "topic_name": null, "id": "8ed8ad41-652c-4688-99cb-534741d18a0a", "choice_type": "single"} {"question": "Survival in unresectable GB carcinoma is", "exp": "Unresectable carcinoma Gallbladder Median survival for patients presenting with unresectable disease is 2-4 months with 1-yr survival is less than 5: Goal of palliation is to relieve jaundice, pain, bowel obstruction and prolongation of life Percutaneous stents are effective for relieving jaundice and should be used as expected survival does not usually warrants a surgical bypass Gemcitabine plus cisplatin (reference regimen) is used for palliation of unresectable disease Ref: Sabiston 20th edition Pgno :1512-1514", "cop": 1, "opa": "4-6 months", "opb": "8-10 months", "opc": "1 year", "opd": "12-24 months", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "48c09df0-4714-4f24-880b-85e7d81a0689", "choice_type": "single"} {"question": "The most impoant factor for maintaining arches of the foot is", "exp": "Factors in maintaining arches of foot are1 The shape of the bones concerned.2 intersegmental ties/staples or ligaments (and muscles) that hold the different segments of the arch together.3 Tie beams or bowstrings that connect the two ends of the arch.4 Slings that keep the summit of the arch pulled up.5 Suspension\"The longitudinal arches are prevented from flattening by the plantar aponeurosis, and by the muscles of the first layer of the sole.\"Ref: Vishram Singh; Volume II; 2nd edition", "cop": 2, "opa": "Shapes of bones", "opb": "Ligaments of plantar aponeurosis", "opc": "Tendons of muscles", "opd": "Intearsal joints", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "40204537-da6c-46de-9a04-039b68570bfb", "choice_type": "single"} {"question": "Medial Umbilical ligament is a remnant of", "exp": "Medial Umbilical ligament is a remnant of Distal part of Umbilical artery. MedianUmbilical ligament is a remnant of Urachus.", "cop": 1, "opa": "Distal part of Umbilical artery", "opb": "Distal part of Umbilical vein", "opc": "Proximal part of Umbilical artery", "opd": "Urachus", "subject_name": "Anatomy", "topic_name": null, "id": "c00e039c-1b0a-4532-8242-380f19bd7c95", "choice_type": "single"} {"question": "Valve of Rosenmuller is located at", "exp": "A fold of mucous membrane found at the junction between the common canaliculus and the lacrimal sac. It is not strictly a valve because fluids can be blown back to emerge at the puncta. It is not always fully developed. ref -medscape.com", "cop": 3, "opa": "Cystic duct", "opb": "Opening of nasolacrimal duct", "opc": "Junction of lacrimal sac and canaliculus", "opd": "Ampulla of vater", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b00a5749-8bdd-475e-b429-e55cf18ef0e7", "choice_type": "single"} {"question": "Necrobiosis lipoidica is seen in", "exp": "Lesions of Necrobiosis lipoidica are found Primarily on the shins and patients can have diabetes mellitus or develop it subsequently .Characeteristic findings include", "cop": 3, "opa": "Diabetes insipudus", "opb": "Lyme disease", "opc": "Diabetes mellitus", "opd": "Symmonds disease", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "d9534523-1075-4ab3-9616-5f585d2a7676", "choice_type": "single"} {"question": "Indication for liver transplantation in an infant is", "exp": "Most common indication for liver transplantation in children - Biliary atresia in adults - Cirrhosis Ref : Bailey & Love 25/e p1426", "cop": 3, "opa": "Alcohol cirrhosis", "opb": "Biliary cirrhosis", "opc": "Biliary atresia", "opd": "Hematochromatosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a6ecc645-6f67-4048-8391-bdce4373d85e", "choice_type": "single"} {"question": "Needle biopsy of solitary thyroid nodule in a young woman with palpable cervical lymph nodes on the same sides demonstrates amyloid in the stroma of lesion. Likely diagnosis is", "exp": "Presence of thyroid nodule along with palpable cervical lymph nodes and amyloid histologically is clearly indicative of Medullary Carcinoma Thyroid, as explained before. Ref : Bailey 25/e p797", "cop": 1, "opa": "Medullary carcinoma thyroid", "opb": "Follicular carcinoma thyroid", "opc": "Thyroid adenoma", "opd": "Multinodular goitre", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "91b75df8-05c3-454a-9d60-6e892fc3f88d", "choice_type": "single"} {"question": "The longest duration of action of insulin preparation is obtained with", "exp": "(Refer Q 17)", "cop": 3, "opa": "Crystal zinc insulin", "opb": "Insulin zinc suspension (Semilente)", "opc": "Protamine zinc insulin", "opd": "Isophane insulin", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "25e6268f-5dbb-4ad3-b6e7-4d55e0da16bf", "choice_type": "single"} {"question": "Opening of esophagus into diaphragm is at the level of", "exp": "Opening of esophagus into diaphragm is at the level of T10. Ref - BDC 6th edition Vol 1 pg282", "cop": 2, "opa": "T6", "opb": "T10", "opc": "T12", "opd": "T8", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "093ad189-ca04-4e2d-b92f-e38b96bc12ea", "choice_type": "single"} {"question": "Refractive index of cornea is", "exp": "Corneal refractive index is 1.376", "cop": 1, "opa": "1.37", "opb": "1.33", "opc": "1.42", "opd": "1.45", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "497c8405-2ab3-4ed1-bf2b-2a9410609a7a", "choice_type": "single"} {"question": "Appendix of testis arise from", "exp": "The paramesonephric ducts remain rudimentary in the male. The greater pa of each duct eventually disappears (Fig. 16.19B). The cranial end of each duct persists as a small rounded body attached to the testis {appendix of testis) which may occasionally give rise to cystsReference: Inderbir Singh Embryology; 10th edition; Page no: 316", "cop": 2, "opa": "Mesonephric duct", "opb": "Paramesonephric duct", "opc": "Mesonephric tubule", "opd": "Genital Tubercle", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "65086ffc-2b3c-4fdb-ab32-4a13ecca8b61", "choice_type": "single"} {"question": "drug transpo mechanisms include", "exp": "Ref-KDT 7/e p11-13 drugs are transpoed across the membrane by passive diffusion and filtration specialized transpo", "cop": 1, "opa": "passive transpo", "opb": "lipid solubility", "opc": "bioavavailability", "opd": "distribution", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e9fa45d0-55e7-4717-849d-b3c2215e3f09", "choice_type": "single"} {"question": "Ductus venosus connects", "exp": "Ductus venosus shunts a poion of the left umbilical vein blood flows directly to the inferior vena cava. Thus, it allows oxygenated blood from the placenta to bypass the liver. BD CHAURASIA'S HUMAN ANATOMY.VOLUME 1. 6T H EDITION.PAGE NO 268", "cop": 3, "opa": "Pulmonary trunk and IVC", "opb": "Right atrium and left atrum", "opc": "Left umbilical vein and IVC", "opd": "Pulmonary trunk and ascending aoa", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "833edfb6-7c3c-4f57-b304-6e2477b35f60", "choice_type": "single"} {"question": "Most common CNS neoplasm in HIV patient is", "exp": "Ref Robbins 9/e p254_255 It is the most common CNS neoplasia in those with AIDS It is of B cell origin and most have caused by EBV in the immunosuppressant persons Histologically reticulon stains demonstrate that the infiltrating cells are separate from one another by silverstraing material .this pattern referred as hopping is characteristics of primary brain lymphoma", "cop": 3, "opa": "Medulloblastoma", "opb": "Astrocytoma", "opc": "Primary CNS lymphoma", "opd": "Ependymoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ef51a829-02e2-45c6-87c4-a4e8d87512e1", "choice_type": "single"} {"question": "Conditions associated with incoagulable state are", "exp": "All the above four options is answer Ref Robbins 7/e p657; 9/e p664-665 severe falciparum malaria: The incidence and progression of coagulation abnormalities were studied in 52 patients with acute falciparum malaria. The patients were prospectively divided into 3 groups; severe (parasitaemia greater than or equal to 5% or vital organ dysfunction), 12 patients; moderate (parasitaemia 1%- less than 5% without complications), 16 patients; and mild (parasitaemia less than 1%), 24 patients. No case died or developed clinical evidence of disseminated intravascular coagulation. Conventional indices of coagulation (prothrombin time, paial thromboplastin time, fibrinogen, fibrin degradation products) were usually within the normal range but reduced plasma concentrations of antithrombin III (AT-III) levels were noted in all groups, and the incidence was significantly higher in patients with severe and moderate malaria (83% and 81%) compared with the mild group (37%; P less than 0.005). Depletion of AT-III was associated with thrombocytopenia, acute promyelocytic leukemia: Acute promyelocytic leukemia (APL) is a is a unique subtype of acute leukemiacharacterized by abnormal proliferation of promyelocytes, life-threatening coagulopathy, and the chromosome translocation t(15;17)(q22;q11-12). heparin overdose: Heparin is an anticoagulant, meaning it inhibits the formation of blood clots in the body. In heparin overdose, the body is unable to deploy its natural defenses against hemorrhage (excessive bleeding), and life-threatening blood loss can occur quickly. Excessive bleeding from an open wound is unlikely to go unnoticed, but internal bleeding can be sneakier. All patients receiving heparin should be monitored closely for the signs and symptoms of internal bleeding due to delayed clotting action abruption placentae: Placental abruption can cause life-threatening problems for both mother and baby. For the mother, placental abruption can lead to: Shock due to blood loss Blood clotting problems (disseminated intravascular coagulation)", "cop": 1, "opa": "Abruption placentae", "opb": "Acute promyelocytic leukaemia", "opc": "Severe falciparum malaria", "opd": "Heparin overdose", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "63d7d909-d632-4c45-8cdc-9b3122077039", "choice_type": "single"} {"question": "The rectum is characterized by the presence of", "exp": "The transverse folds of the rectum (or Houston&;s valves) are semi-lunar transverse folds of the rectal wall that protrude into the rectum. These folds are about 12 mm. in width and are composed of the circular muscle coat of the rectum. They are usually three in numberTaenia coli, haustrations and appendices epiploicae are features of ColonRef: Vishram Singh; Volume II; 2nd edition; Page no: 282", "cop": 3, "opa": "Taenia coli", "opb": "Haustrations", "opc": "Permanent transverse mucosal folds within lumen", "opd": "Appendicis epiploicae", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "a445d338-afb0-4df0-a1f8-496297a94816", "choice_type": "single"} {"question": "Most impoant prognostic factor of Wilms tumor", "exp": "histology remains a critical determinant of adverse prognosis. Even anaplasia restricted to the kidney (i.e., without extra-renal spread) confers an increased risk of recurrence and death, emphasizing the need for accurate identification of this histologic feature. Molecular parameters that correlate with adverse prognosis include loss of genetic material on chromosomes 11q and 16q, and gain of chromosome 1q inthe tumor cells. Along with the increased survival of individuals with Wilms tumor have come repos of an increased risk of developing second primary tumors, including bone and soft-tissue sarcomas, leukemia", "cop": 2, "opa": "Histopathology and ploidy of cells", "opb": "Tumor stage", "opc": "Age of patient", "opd": "Mutation of chromosome 1p", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "9927aff0-d66e-4d08-ac25-13008dc12c3e", "choice_type": "single"} {"question": "anorexia nervosa is common in", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "adolescents", "opb": "middle age", "opc": "males", "opd": "old age", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "bfbf7532-acf5-4746-a327-103ec294667a", "choice_type": "single"} {"question": "Poal vein is formed by the union of", "exp": "The poal vein is usually formed by the confluence of the superior mesenteric and splenic veins and also receives blood from the inferior mesenteric, gastric, and cystic veins. Ref - BDC 6e vol2 pg282", "cop": 2, "opa": "Splenic and inferior mesentric veins", "opb": "Splenic and superior mesentric veins", "opc": "Right and left hepatic veins", "opd": "Hepatic and splenic veins", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "7699cbb1-fd34-48da-af6e-8490a330ee82", "choice_type": "single"} {"question": "Appendices epiploicae present in", "exp": "The epiploic appendices are small pouches of the peritoneum filled with fat and situated along the colon, but are absent in the rectum. Ref - researchgate.net", "cop": 4, "opa": "Appendix", "opb": "Caecum", "opc": "Rectum", "opd": "Sigmoid colon", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "7899a6c1-6c86-4246-843a-b70b2b6ca838", "choice_type": "single"} {"question": "Division of long thoracic nerve results in", "exp": "Nerve to serratus anterior is also called long thoracic nerve(C5,C6,C7). A)Serratus anterior muscle along with the pectoralis minor pulls the scapula forwards around the chest wall to protract the upperlimb. B)The fibres inseed into the inferior angle of the scapula pull it forwards and rotate the scapula so that the glenoid cavity is turned upwards.In this action,the serratus anterior is helped by the trapezius which pulls the acromion upwards and backwards. when the muscle is paralyzed,the medial margin of the scapula gets raised specially when 'pushing movements' are attempted.This is called 'winging of scapula'. REF.B D Chaurasia's human anatomy,Vol.1,pg.47", "cop": 4, "opa": "Inability to retract the scapula", "opb": "Wasting of pectoralis major muscle", "opc": "Weakness of adduction of humerus", "opd": "Winging of scapula", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "5f4d2928-eff3-400e-a5a9-e17f6a9cb585", "choice_type": "single"} {"question": "The nerve supply of nail bed of index finger is", "exp": "Palmar branches of the median nerve supplies the nail bed of lateral 3 and a half digits Reference: BD Chaurasia 7th edition diagram page no:182.", "cop": 3, "opa": "Superficial br of radial nerve", "opb": "Deep br of radial nerve", "opc": "Median nerve", "opd": "Ulnar nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "243088b8-c247-4eb4-a84b-a898f41a2b18", "choice_type": "single"} {"question": "Not a content of adductor canal is", "exp": "ADDUCTOR CANAL:- Also known as Hunter's or subsaorial canal.It is an intermuscular space situated on the medial side of the middle one-third of the thigh. Extend:-from apex of femoral triangle above to the tendinous opening in adductor magnus below.Shape:- Triangular on cross section. Boundaries:--Anterolateral wall : vastus medialis.-Posteriomedial wall/Floor:Adductor longus above and adductor magnus below.-Medial wall/Roof: strong fibrous membrane joining Anterolateral and posteromedial walls.Roof overlapped by saorius. Subsaorial plexus of nerves lies on the fibrous roof of the canal under saorius. Plexus is formed by branches from the medial cutaneous nerve of thigh,the saphenous nerve and the anterior division of the obturator nerve. It supplies skin over fascia lata and neighbouring skin. Contents:-1. Femoral aery:enters the canal at the apex of the femoral triangle. Within the canal it gives off muscular branches and descending genicular branch. It leaves the canal through opening in adductor Magnus to continue as popliteal aery.2. Femoral vein lies posterior to femoral aery( upperclassmen pa) and lateral to the aery ( lower pa).3. Saphenous nerve:cross the femoral aery anteriorly from lateral to medial side.4. Nerve to vastus medialis5. Branches of two divisions of obturator nerve: Anterior division emerges at the lower border of adductor longus, gives branches to subsaorial plexus and ends by supplying femoral aery. Posterior division of the obturator nerve runs on anterior surface of adductor magus and ends by supplying knee joint. {Reference: BDC 6Epg no.56}", "cop": 4, "opa": "Femoral aery", "opb": "Femoral vein", "opc": "Saphenous nerve", "opd": "Nerve to vastus lateralis", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "03377881-e8fe-4817-9e0f-bcac552dd332", "choice_type": "single"} {"question": "Single unit smooth muscles are seen in", "exp": null, "cop": 3, "opa": "Iris", "opb": "Ductus deferens", "opc": "Ureter", "opd": "Trachea", "subject_name": "Anatomy", "topic_name": null, "id": "7c0cee65-a382-4c2c-b2e1-30265f675cca", "choice_type": "single"} {"question": "Skull consists of....bones", "exp": "B i.e. 22", "cop": 2, "opa": "20", "opb": "22", "opc": "24", "opd": "28", "subject_name": "Anatomy", "topic_name": null, "id": "ff610047-536b-4ad7-9ced-937d426f7238", "choice_type": "single"} {"question": "Palmar interossei is absent in", "exp": "Palmar interossei is absent im middle finger. Dorsal interossei is absent in Thumb & Little finger.", "cop": 2, "opa": "Thumb", "opb": "Middle finger", "opc": "Ring finger", "opd": "Little finger", "subject_name": "Anatomy", "topic_name": null, "id": "8e09f6ae-e117-4af0-b942-005e1a32263e", "choice_type": "single"} {"question": "The most dependable means of personal identity is", "exp": "Finger print or dactylography is the most dependable means", "cop": 2, "opa": "Anthropometry", "opb": "Dactylography", "opc": "Super imposition", "opd": "Photography", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ca812f8a-48ea-4db1-89c5-a797ad7c5e00", "choice_type": "single"} {"question": "Total number of dorsal interossei", "exp": "There are 4 dorsal interossei muscles and 4 palmar interossei muscles. Dorsal and palmar interossei are supplied by the deep branch of the ulnar nerve. Dorsal interossei help in the abduction of digits. Ref: BD Chaurasia 7th edition; Page no: 182", "cop": 3, "opa": "2", "opb": "3", "opc": "4", "opd": "5", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "3feead10-db93-4941-beca-2a0c6bde7ec9", "choice_type": "single"} {"question": "Acute emphysematous cholecystitis is caused by", "exp": "Emphysematous cholecystitis It is thought to begin with acute cholecystitis (calculous or acalculous), followed by ischaemia or gangrene of GB wall and infection by gas producing organisms. Causative organisms of Emphysematous Cholecystitis Anaerobes : Clostridium welchi or Cl. Perfringens Aerobes : E.coli Ref: Sabiston 20th edition Pgno : 1493", "cop": 3, "opa": "Pseudomonas aeruginosa", "opb": "Staphylococcus", "opc": "Clostridium perfringens", "opd": "Streptococcus pyogenes", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f25caa8b-6391-45ca-98ac-9351345f0aab", "choice_type": "single"} {"question": "Clitoris develops from", "exp": "Human embryology Tenth edition Inder Bir Singh Page no 301 The genital tubercle becomes cylindrical and forms the clitoris Genital tubercle is situated in the midline between the urogenital membrane and lower pa of anterior abdominal wall In males genital tubercle forms penis", "cop": 1, "opa": "Genital tubercle", "opb": "Genital ridge", "opc": "Wolfian duct", "opd": "Mullerian duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6e0aeffb-329f-467b-baaf-7e253877d5dd", "choice_type": "single"} {"question": "Disulfiram is used to treat", "exp": "DISULFIRAM is a DETERRANT which acts by blocking acetaldehyde dehydrogenase When acetaldehyde dehydrogenase is blocked there will be increased amount of acetaldehyde that acts on mast cells and results in release of histamine that in turn leads to allergic reaction. Thus when a patient on disulfiram takes alcohol there would be allergic reaction that prevents the patient from using the substance Ref.Kaplon and Sadock, synopsis of Psychiatry, 11 th edition, pg No.625", "cop": 2, "opa": "Opioid dependence", "opb": "Alcohol dependence", "opc": "Cocaine dependence", "opd": "Amphetamine dependence", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "92ca4d18-1cab-4d0d-b6e2-f1489e741423", "choice_type": "single"} {"question": "Transformation of one epithelium to other epithelium", "exp": "Ref Robbins 8/e p10,11; 9/e p37 Metaplasia is a reversible change in which one adult cell type (epithelial or mesenchymal) is replaced by another adult cell type. In this type of cellular adaptation, a cell type sensitive to a paicular stress is replaced by another cell type better able to withstand the adverse environment. Metaplasia is thought to arise by reprogramming of stem cells to differ- entiate along a new pathway rather than a phenotypic change (transdifferentiation) of already differentiated cells. Epithelial metaplasia is exemplified by the squamous change that occurs in the respiratory epithelium of habitual cigarette smokers (Fig. 1-5). The normal ciliated columnar epithelial cells of the trachea and bronchi are focally or widely replaced by stratified squamous epithelial cells. The rugged stratified squamous epithelium may be able to survive the noxious chemicals in cigarette smoke that the more fragile specialized epithelium would not tolerate. Although the metaplastic squamous epithelium has survival advantages, impoant protective mechanisms are lost, such as mucus secretion and ciliary clearance of paiculate matter. Epithelial metaplasia is therefore a double-edged sword. Moreover, the influences that induce metaplastic change, if per- sistent, may predispose to malignant transformation of the epi- thelium. In fact, squamous metaplasia of the respiratory epithelium often coexists with lung cancers composed of malignant squamous cells. It is thought that cigarette smoking initially causes squamous metaplasia, and cancers arise later in some of these altered foci. Since vitamin A is essential for normal epithelial differentiation, its deficiency may also induce squamous metaplasia in the respiratoryepithelium. Metaplasia need not always occur in the direc- tion of columnar to squamous epithelium; in chronic gastric reflux, the normal stratified squamous epithelium of the lower esophagus may undergo metaplastic transformation to gastric or intestinal-type columnar epithelium. Metapla- sia may also occur in mesenchymal cells but in these situ- ations it is generally a reaction to some pathologic alteration and not an adaptive response to stress. For example, bone is occasionally formed in soft tissues, paicularly in foci of injury.", "cop": 4, "opa": "Dysplasia", "opb": "Hyperplasia", "opc": "Neoplasia", "opd": "Metaplasia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "72e3a858-b804-45d9-b60f-409c38468588", "choice_type": "single"} {"question": "Veins not involved in stomach varices", "exp": "Gastric varices Gastric varices can develop secondary to poal hypeension, in conjunction with esophageal varices, or secondary to sinistral hypeension from splenic vein thrombosis In generalised poal hypeension, the increased poal pressure is transmitted by the left gastric vein to esophageal varices and by the sho and posterior gastric veins to the fundic plexus and cardiac veins Isolated gastric varices tend to occur secondary to splenic vein thrombosis Splenic blood flows retrograde through the sho and posterior gastric veins into the varices, then hepatomegaly through the coronary vein into the poal vein. Left to right retrograde flow through the gastriepiploic vein to the superior mesenteric vein can explain the development of ectopic varices in the stomach Ref: Sabiston 20th edition Pgno : 1232", "cop": 4, "opa": "Coronary vein", "opb": "Right gastroepiploic vein", "opc": "Sho gastric vein", "opd": "Splenic vein", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "28107dcf-11fe-4ce1-818a-008afe7f9eb1", "choice_type": "single"} {"question": "Structure posterior to transverse pericardial sinus is", "exp": "The transverse sinus is a horizontal gap between the aerial and venous ends of the hea tube.It is bounded anteriorly by the ascending aoa and pulmonary trunk,and posteriorly by the superior venacava and inferiorly by the left atrium on each side it opens into the general pericardial cavity. REF.B D Chaurasia's human anatomy vol.1,fifth edition", "cop": 3, "opa": "Aoa", "opb": "Pulmonary trunk", "opc": "SVC", "opd": "Left atrium", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "c0af97c2-c82f-4462-a9dd-1ef08dc04ea4", "choice_type": "single"} {"question": "Cricothyroid muscle is supplied by", "exp": "Ref BDC volume 3;sixth edition pg 257 All intrinsic muscles of the larynx are supplied by the recurrent laryngeal nerve except for the cricothyroid which is supplied by the external laryngeal nerve.", "cop": 3, "opa": "Recurrent laryngeal nerve", "opb": "Inferior laryngeal nerve", "opc": "Superior laryngeal nerve", "opd": "Nerve of galen", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "21ace5d7-ea16-4b7c-8b6d-80f1650d8297", "choice_type": "single"} {"question": "De Quervain's disease is tenosynovitis of", "exp": "-Exterior pollicis brevis & abductor pollicis longus tendons. - form the anterolateral border of anatomical Snuff box. -It occurs d/o repeated overuse of thumb/ wrist paicularly like thumb abduction. -Finkelstien test : Sudden ulnar detion is painful. -Anatomical snuff box Triangular depression on lateral side of wrist seen best when thumb is extended. Boundaries :- -Anterolateral - Abductor policies longus tendon Exterior pollicis brevis tendon -Posteromedial - Exterior pollicis longus tendon -Floor - Scaphoid & trapezium Contents - Radial aery, radial nerve, cephalic vein", "cop": 3, "opa": "Abductor pollicis brevis and extensor pollicis longus", "opb": "Abductor pollicis longus and extensor carpi radialis brevis", "opc": "Abductor pollicis longus and extensor pollicis brevis", "opd": "Abductor pollicis brevis and extensor carpi radialis longus", "subject_name": "Anatomy", "topic_name": "NEET 2018", "id": "32fae73a-5f92-4806-84fc-0da4baa4bbd8", "choice_type": "single"} {"question": "Pulp of the index finger is supplied by", "exp": "Ans. is 'a' i.e., Median nerve Sensory supply of HandOn Palmar side* Lateral 2/3 of the palm and lateral three and half fibers - Median nerve* Medial 1/3 of the palm and medial one and half fingers - Ulnar nerveOn Dorsal surface* Distal phalanx of lateral three and half ditits -Median nerve* Medial 1/3 of dorsum of hand and medial one and half fingers - Ulnar nerve* Lateral 2/3 of dorsum of hand -Radial nerve* Dorsum of lateral three and half fingers over proximal and middle phalanges - Radial nerve* Sensory distribution of upper limb is as followThe cutaneous nervesRegion suppliedNerve(s)Root valueDerived fromUpper part of pectoral region, and skin over upper part of deltoidSupraclavicularC3,C4Cervical plexusArm 1. Upper medial partIntercostobrachialT22nd intercostal2. Lower medial partMedial cutaneous nerve of armT1,T2Medial cord3. Upper lateral part (including skin over lower part of deltoid)Upper lateral cutaneous nerve of armC5, C6Axillary nerve4. Lower lateral partLower lateral cutaneous nerve of armC5, C6Radial nerve5. Posterior aspectPosterior cutaneous nerve of armC5Radial nerveForearm 1. Medial sideMedial cutaneous nerve of forearmC8,T1Medial cord2. Lateral sideLateral cutaneous nerve of forearmC5> C6Musculocutaneous3. Posterior sidePosterior cutaneous nerve of forearmC6, C7, C8Radial nervePalm 1. Lateral two-thirdsPalmar cutaneous branch of medianC6, C7Median2. Medial one-thirdPalmar cutaneous branch of ulnarC8UlnarDorsum of hand 1. Medial half including proximal phalanges of medial 2 1/2 digitsDorsal branch of ulnarC8Ulnar2. Lateral half including proximal phalanges of medial 2 1/2 digitsSuperficial terminal branch of radialC6, C7RadialDigits Palmar aspect, and dorsal aspect of middle and distal phalanges 1. Lateral 3V6 digitsPalmar digital branch of medianC7Median2. Medial 1 Vi digitsPalmar digital branch of ulnarC8Ulnar", "cop": 1, "opa": "Median nerve", "opb": "Radial nerve", "opc": "Ulnar nerve", "opd": "Axillary nerve", "subject_name": "Anatomy", "topic_name": "Upper Extremity", "id": "46906a15-11e0-49fd-9822-a259521db007", "choice_type": "single"} {"question": "Poal Acinus means", "exp": "The hepatic or poal acinus is the functional unit of the liver.The acinus consists of an irregular shaped, roughly ellipsoidal mass of hepatocytes aligned around the hepatic aerioles and poal venules just as they anastomose into sinusoids.The acinus is roughly divided into zones that correspond to distance from the aerial blood supply - those hepatocytes closest to the aerioles (zone 1 below) are the best oxygenated, while those fahest from the aerioles have the poorest supply of oxygen. This arrangement also means that cells in the center of the acinus (again, zone 1) are the first to \"see\" and potentially absorb blood-borne toxins absorbed into the poal blood from the small intestine.Reference: Krishna Garg Histology; 5th edition; Page no: 171", "cop": 1, "opa": "The space between two central veins of adjacent lobules", "opb": "The space between two hepatic ducts", "opc": "The space between central vein and bile duct", "opd": "The space between Poal vein and central vein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9301e1b0-83af-409d-8d31-11f82a609a7f", "choice_type": "single"} {"question": "The distance of aoic constriction of the oesophagus from the upper incisor teeth", "exp": "First constriction, at the pharyngo-esophageal junction, 9 cm (6 inches) from the incisor teeth. Second constriction, where it's crossed by the arch of aoa, 22.5 cm (9 inches) from the incisor teeth. Third constriction, where it's crossed by the left principal bronchus, 27.5 cm (11 inches) from the incisor teeth. Fouh constriction, where it pierces the diaphragm, 40 cm (15 inches) from the incisor teeth. Ref - sciencedirect.com", "cop": 2, "opa": "15 cm", "opb": "22.5 cm", "opc": "27.5 cm", "opd": "40 cm", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f0f27f10-d0b0-486e-b7b6-1a7cd8f735e3", "choice_type": "single"} {"question": "Muscle attached to the tubercle of 1st cervical vertebrae", "exp": null, "cop": 2, "opa": "Scalenus anterior", "opb": "Scalenus medium", "opc": "Scalenus minimum", "opd": "Scalenus posterior", "subject_name": "Anatomy", "topic_name": null, "id": "f4e188ef-e2c0-47b8-835f-db80d6d3c0a9", "choice_type": "single"} {"question": "The gold standard for the definitive diagnosis of the extrahepatic biliary atresia is", "exp": "Biliary atresia Evaluation of biliary anatomy begins with ultrasound Other imaging modalities such as HIDA scintigraphy, MRCP and ERCP have been used with varying success Although these are useful adjuncts, liver biopsy is gold standard for the diagnosis of biliary atresia and can safely be done percutaneously under local anaesthesia Ref: Sabiston 20th edition Pgno : 639", "cop": 4, "opa": "Per operative cholangiography", "opb": "Hepatobiliary scintigraphy", "opc": "Alkaline phosphatase level", "opd": "Liver biopsy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d45904aa-fb66-473e-9f80-037a0932d06e", "choice_type": "single"} {"question": "Splenectomy is most useful in", "exp": "Ref Harrison 19 th ed pg 652 We do not have a causal treatment for HS; i.e., no way has yet been found to correct the basic defect in the membrane-cytoskeleton structure. Given the special role of the spleen in HS ), it has long been thought that an almost obligatory therapeutic mea- sure was splenectomy. Because this operation may have more than tril consequences, today we have more aiculate recommenda- tions, based on disease severity (having found out, whenever pos- sible, about the outcome of splenectomy in the patient's relatives with HS), as follows. In mild cases, avoid splenectomy.", "cop": 2, "opa": "Thrombocytopenia", "opb": "Hereditary spherocytosis", "opc": "H.S.purpura", "opd": "Sickle cell anemia", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "a796c269-e73a-4df4-8c86-a165e3874e0c", "choice_type": "single"} {"question": "sialorrhea is a side effect of", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients * Side effects * Agranulocytosis * Myocarditis * Seizure * Constipation * Weight gain * Metabolic syndrome Sialorrhea Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 4, "opa": "amisulpride", "opb": "olanzapine", "opc": "aripiprazole", "opd": "clozapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "d61556ed-0162-4f9f-9117-e645f56865be", "choice_type": "single"} {"question": "Auerbanchs plexus and Meissners ganglion cell are derived from", "exp": "C i.e. Neural Crest", "cop": 3, "opa": "Yolk sac", "opb": "Primordial germ cell", "opc": "Neural Crest", "opd": "Fetal GIT", "subject_name": "Anatomy", "topic_name": null, "id": "810e922c-d0d2-474b-b5f0-4affe129530a", "choice_type": "single"} {"question": "Inferior mesenteric vein drains into", "exp": "Inferior mesenteric vein usually terminates when reaching the splenic vein, which goes on to form the poal vein with the superior mesenteric vein (SMV).", "cop": 1, "opa": "Splenic vein", "opb": "Renal vein", "opc": "Inferior vena cava", "opd": "Superior mesenteric vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "302661f7-23d1-4e55-a035-fd22d7517a46", "choice_type": "single"} {"question": "Endothelial leukocyte interaction during inflammation is mediated by", "exp": "Ref Robbins 9/e p76 Endothelial leucocytes interaction is also mediated by integrins Integrins are proteins that function mechanically, by attaching the cell cytoskeleton to the extracellular matrix (ECM), and biochemically, by sensing whether adhesion has occurred. The integrin family of proteins consists of alpha and beta subtypes, which form transmembrane heterodimers", "cop": 1, "opa": "Selectins", "opb": "Integrins", "opc": "Defensins", "opd": "Endothelin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4dcc2d6b-948d-4d4e-922c-c80ec8246da4", "choice_type": "single"} {"question": "One of the following disorders is due to maternal disomy", "exp": "ref Robbins 9/e p173 Matetnal disomy is associated with disorders like prader Willi syndrome, angelman syndrome.", "cop": 1, "opa": "Prader Willi syndrome", "opb": "Angelman syndrome", "opc": "Hydatidi form mole", "opd": "Klinefelter syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3e5a2e35-214d-4fdb-9bee-5ca14bcc6f3e", "choice_type": "single"} {"question": "Most common liver tumor in children", "exp": ".", "cop": 1, "opa": "Hemangioma", "opb": "Non-parasitic cyst", "opc": "Adenoma", "opd": "Focal nodular hyperplasia", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "c2705b78-795c-4441-853f-0fe0d51b8ca5", "choice_type": "single"} {"question": "Maxillary aery is", "exp": "Branches of external carotid aery Anterior Superior thyroid Lingual Facial Posterior Occipital Posterior auricular Medial Ascending pharyngeal Terminal Maxillary Superficial temporal Ref BDC volume 3 ;sixth edition pg 101", "cop": 4, "opa": "Branch of facial aery", "opb": "Branch of internal carotid aery", "opc": "Branch of common carotid", "opd": "Terminal branch of external carotid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "84048e94-d814-442a-808a-879d0445a416", "choice_type": "single"} {"question": "Crouzon syndrome consists of", "exp": "Crouzon syndrome consists of Autosomal dominant (FGFR2 Gene) Craniosynostosis involving coronal suture Wide set bulging eyes and beaked nose Maxillary hypoplasia Underdeveloped upper jaw& protruding lower jaw Dental problems, hearing loss Hydrocephalus Ref: Nelson's, 20th edition, page 2819", "cop": 1, "opa": "Maxillary hypoplasia", "opb": "Syndactyly", "opc": "Macrocephaly", "opd": "Microcephaly", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6df1a071-84a9-4fbb-ab9f-b6e94f480788", "choice_type": "single"} {"question": "Foaming liver is seen in", "exp": "Gas Gangrene Clinical features Severe local wound pain and crepitus (gas in the tissues, which may also be noted on plain radiographs) The wound produces a thin, brown, sweet smelling exudate, in which Gram staining will reveal bacteria Gas and smell are characteristic (Myonecrosis) If septicemia occurs, gas may be produced in the other organs, notably liver known as 'foaming liver' Edema and spreading gangrene follow the release of collagenase, hylauronidase, other proteases and alpha toxin Early systemic complications with circulatory collapse and multi organ failure follow if prompt action is not taken Ref: Harrison's 19th edition Pgno :992", "cop": 2, "opa": "Actinomycosis", "opb": "Gas gangrene", "opc": "Organophosphorus poisoning", "opd": "Sepsis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "96d9fb07-cab8-43f5-9871-4c47c6a38874", "choice_type": "single"} {"question": "Left testicular vein drains into", "exp": "The veins emerge from the back of the testis, and receive tributaries from the epididemis; they unite and form a convoluted plexus, which constitutes the greater mass of the spermatic cord; the vessels composing this plexus are very numerous, and ascend along the cord, in front of the ductus difference.Below the subcutaneous inguinal ring, they unite to form three or four veins, coalesce to form two veins. These unite to form a single vein, which opens, on the right side, into the inferior vena cava (at an acute angle), on the left side into the left renal vein (at a right angle). ref - BDC 6e vol2 pg 225", "cop": 1, "opa": "Left renal vein", "opb": "Inferior vena cave", "opc": "Common iliac vein", "opd": "Internal iliac vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "ca3a3f20-1b01-4b7b-9a06-6ab654498efc", "choice_type": "single"} {"question": "Not seen in colon", "exp": "Peyer's patch are aggregations of gut assossiated lymphoid tissue that are usually found in the lowest poion of the small intestine, the ileum, in humans; as such, they differentiate the ileum from the duodenam and jejunam. The duodenum can be identified by burnners gland. The jejunum has neither Brunner's glands nor Peyer's patches. Ref - BDC vol2 pg257,264", "cop": 2, "opa": "Taeniae", "opb": "Pyer's patches", "opc": "Sacculations", "opd": "Appendices", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "84b4888e-2ba2-415d-9ea2-1fcd55eb52e6", "choice_type": "single"} {"question": "metabolic syndrome is a side effect of", "exp": "CLOZAPINE * Impoance * First SGA * TREATMENT FOR TREATMENT RESISTANT SCHIZOPHRENIA * TOC for TD * Anti suicidal * Psychosis in parkinsonian patients * Side effects * Agranulocytosis * Myocarditis * Seizure * Constipation * Weight gain * Metabolic syndrome Sialorrhea Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 935", "cop": 1, "opa": "clozapine", "opb": "aripiprazole", "opc": "topiramate", "opd": "ziprasidone", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2926cbd0-0227-479d-a6a3-504c58ad7313", "choice_type": "single"} {"question": "Pseudopancreatic cyst is", "exp": "Pseudopancreatic cyst A chronic collection of pancreatic fluid surrounded by a nonepithelized wall of granulation tissue and fibrosis Pseudocyst accounts 75% of cystic lesions of the pancreas Most common complication of chronic pancreatitis Located anywhere from the mediastinum to the scrotum Found most often in the lesser sac or anterior pararenal space Traumatic pseudocysts tend to occur anterior to the body of the gland Chronic pancreatitis pseudocyst are commonly located within the substance of the gland Incidence of pseudocyst :, Acute pancreatitis (10-20%) of patients. Chronic pancreatitis (20-40%) of patients Multiple in 17% cases Alcohol is the most common cause of pancreatitis related pseudocyst Ref: Sabiston 20th edition Pgno :1531", "cop": 2, "opa": "Post traumatic cyst", "opb": "Post Inflammatory cyst", "opc": "Congenital cyst", "opd": "Neoplastic cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "67adb7f4-5509-43ce-97bd-fb1661107e3f", "choice_type": "single"} {"question": "Honey comb liver is seen in", "exp": "The liver is the \"primary\" site of infection in 15% with abdominal actinomycosis.\" Presumably, Actimomyces are conveyed to the liver by the poal vein. The lesion develops after appendicitis or surgery for noninflammatory diseases in most instances,4-6 but there are repos in which the pathogenesis is un- Clear.'.' The most common hepatic lesion is a solitaryabscess, though multiple abscesses also occur. A honeycomb appearance in cross-section suggest an origin of the abscess from multiple, smaller ones. Abscesses are usually confined to the liver, but may extend to involve adjacent organs and even to reach the pleural space.\",'\" Liver abscesses can rarely arise by direct extension from such foci as an abscess in the neck.\"", "cop": 3, "opa": "Micronodular cirrhosis", "opb": "Dubin-Johnson syndrome", "opc": "Actimomycosis", "opd": "Hydatidosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "9023be81-a6cd-44d3-9343-a1af6cbf838c", "choice_type": "single"} {"question": "Stomach completes its rotation by", "exp": "At 5 weeks Stomach rotates and dilates. The intestinal loop begins to form.At 6 weeks Intestinal loop is well formed.Stomach completes rotation At 7 weeks Intestinal loop herniates out of the abdominal cavityAt 8 weeks Intestinal loop rotates counterclockwiseAt 3 months Herniated coils of intestine return to the abdominal cavity.Reference: Inderbir Singh Embryology; 10th edition; Page no: 200", "cop": 2, "opa": "4 weeks", "opb": "6 weeks", "opc": "7 weeks", "opd": "8 weeks", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "70571a80-34eb-46f3-a3db-f9e074fbeff9", "choice_type": "single"} {"question": "Climbing fibres of cerebellar coex are", "exp": "Afferent fibres to cerebellum are climbing fibres (olivocerebellar from inferior olivary nuclei) and mossy fibres (other pas of body)", "cop": 1, "opa": "Olivocerebellar", "opb": "Spinocerebellar", "opc": "Pontocerebellar", "opd": "Vestibulocerebellar", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d2599da0-4488-432e-bb46-9b14f154c5a8", "choice_type": "single"} {"question": "Shoest acting local anaesthetic", "exp": ".", "cop": 4, "opa": "Procaine", "opb": "Xylocaine", "opc": "Bupivacaine", "opd": "Chloroprocaine", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "4c7ba2c2-b050-4ec4-af1a-e00d461ff72d", "choice_type": "single"} {"question": "Sudden onset of a cough followed by increasing dyspnea is characteristic of", "exp": "PneumothoraxPatients most commonly present with chest pain, often sharp and pleuritic and may leads to severe respiratory embarrassment or becomes dull and persistent.Dyspnea is the 2ndMC symptom.Less common symptoms include a nonproductive cough and ohopnea.Physical findings may be normal if the Pneumothorax is less than 25%.Characteristic physical finding includes diminished chest excursion and hyper-resonance on percussion of the affected side. Breath sounds are diminished to absent.(Refer: Harrison's Principles of Internal Medicine, 18thedition, pg no: 2181, 2221, 3212)", "cop": 4, "opa": "Pleural effusion", "opb": "Lobar pneumonia", "opc": "Myocardial infarct", "opd": "Pneumothorax", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "3ca8863f-a793-4a1a-a417-e0ad9965af7d", "choice_type": "single"} {"question": "Sturge Weber syndrome is associated with", "exp": "Sturge Weber syndrome is manifested at bih by po wine stain forehead and upper eyelid of one side of the face. Refer robbins 9/e p196", "cop": 1, "opa": "Po wine staine", "opb": "Cavernous hemangioma", "opc": "Lymphangioma", "opd": "Haemangiosarcoma", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "34bade0d-65ec-4282-8d69-6edd3339fe18", "choice_type": "single"} {"question": "Irresistible desire to pull out hair", "exp": "Trichotilomania Irresistible desire to pull out hair Dipsomania Irresistible desire to drink alcohol Nymphomania Irresistible desire to have sexual intercourse including sexual perversions, in female. Satyriasis Irresistible desire to have sexual intercourse including sexual perversions, in male. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 360", "cop": 2, "opa": "Dipsomania", "opb": "Trichotilomania", "opc": "Nymphomania", "opd": "Satyriasis", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "d3583d98-d648-4082-bcca-2be85fb8f4cb", "choice_type": "single"} {"question": "Joint involved in movement of head from left to right.", "exp": "Answer A. Atlanto axialAtlanto-occipital (between skull and C1) joint permit nodding of head ( as when indicating approval or YES) and Atlanto-axial joint permits the head to be turned from side to side (as indicating disapproval or NO).", "cop": 1, "opa": "Atlanto axial", "opb": "Atlanto occipital", "opc": "C2- C3 Joint", "opd": "C3- C4 Joint", "subject_name": "Anatomy", "topic_name": null, "id": "1664e7e3-16c1-482f-a5f4-23793118f4f3", "choice_type": "single"} {"question": "Foramen Transversarium transmit", "exp": "Foramen transversarium transmits 1st, 2nd, pa of the veebral aery which is present in the cervical veebra Ref: Gray's 40e/p-250-251", "cop": 4, "opa": "Inferior jugular vein", "opb": "Inferior petrosal sinus", "opc": "Sigmoid sinus", "opd": "Veebral aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "056c2baf-1ecf-4a18-aca0-0893365b1379", "choice_type": "single"} {"question": "Worst prognosis memingioma is", "exp": "Atypical and anaplastic meningiomas are uncommon tumors with a poorer prognosis than benign meningiomas. We reviewed the current literature and attempted to integrate and summarize available information to determine a logical approach to these tumors. Both tumors are rare and are often integrated with benign meningiomas when treatments are evaluated. In addition, because there has not been one histopathological classification scheme for atypical and anaplastic meningiomas in the past, there are numerous inconsistencies in the literature. Malignant progression with accumulation of mutations in a benign meningioma can result in an atypical and/or anaplastic meningioma. Both tumors are difficult to manage and have high recurrence and poor survival rates. The extent of tumor resection and histological grade are the key determinants for recurrence. In addition, metastases are unusual, but they do occur. We also review the evidence available that has resulted in the current World Health Organization classification. Radiation therapy can be used as an adjunctive treatment after both total and subtotal resection. In addition, the role of stereotactic radiosurgery is increasing, along with a possible role for brachytherapy. There are no effective chemotherapeutic agents available. A treatment algorithm is suggested. Refer Robbins page no 1315", "cop": 3, "opa": "Syncitial", "opb": "Fibroblastic", "opc": "Anplastic", "opd": "Atypical", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "f6381ae2-7c94-4b57-bafd-9a071df08807", "choice_type": "single"} {"question": "Sensory fibres from the taste buds in the hard and soft palate travel along", "exp": "Special sensory or gustatory nerves carrying taste sensations from the oral surface are contained in the lesser palatine nerves. The fibres travel through the greater petrosal nerve to the geniculate ganglion of the facial nerve and from there to the nucleus of the solitary tract. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th.", "cop": 2, "opa": "Trigeminal nerve", "opb": "Facial nerve", "opc": "Glossopharynegeal nerve", "opd": "Vagus nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "c7d99d8d-fb07-4a70-b97c-ea9ffa6b53a7", "choice_type": "single"} {"question": "Panniculus Adiposus is seen in", "exp": "The panniculus adiposus is the fatty layer of the subcutaneous tissues, superficial to a deeper vestigial layer of muscle, the panniculus carnosus. Hence it is seen in orbit and protects the eye ball.", "cop": 2, "opa": "Scrotum", "opb": "Orbit", "opc": "Eyelid", "opd": "Penis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a4539d72-0236-493f-a711-5ed62d3f38a5", "choice_type": "single"} {"question": "The ideal treatment for hemothorax greater than 500ml/hr", "exp": "Following are indications of thoracotomy in blunt chest trauma: Initial drainage of blood > 1000 ml, especially if fresh. Continued brisk bleeding > (100 ml/15 minutes) from the intercostal drain Continued bleeding of > 200 ml/hr for > 3 hrs Rupture of bronchus, aoa, esophagus or diaphragm Cardiac tamponade (if needle aspiration unsuccessful). Ref : Bailey & Love 24/e p872", "cop": 4, "opa": "wait and watch", "opb": "Needle aspiraton", "opc": "Intercostal tube", "opd": "Open thoracotomy with ligation of vessels", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "074359ef-2000-4a52-9438-0e0d4659a6e5", "choice_type": "single"} {"question": "Ascorbic acid is a potent enhancer of iron absorption because it", "exp": "Ascorbic acid enhances iron absorption mostly by its reducing capacity, keeping iron in the ferrous state. Ascorbic acid does not enhance heme iron absorption, nor does it affect heme oxygenase activity or the produc on of ferritin or transferrin.", "cop": 3, "opa": "Enhances the absorption of heme iron", "opb": "Enhances the activity of heme oxygenase", "opc": "Is a reducing agent, thereby helping to keep iron in the ferrous state", "opd": "Decreases the production of ferritin by enterocytes", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "89f196fa-9d25-48e3-be78-d668f9ab0506", "choice_type": "single"} {"question": "Massive blood transfusion is defined as", "exp": "According to Schwaz Massive transfusion is a single transfusion of 2500 or 5000 ml over a period of 24 hours .", "cop": 4, "opa": "500 ml in 10 min", "opb": "250 ml in 5 min", "opc": "1 unit in 1 hour", "opd": "2500 ml or 5000 ml in 24 hours", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "eb54abb4-c007-4540-99af-84e5454840ce", "choice_type": "single"} {"question": "The drug that should be used for prophylaxis of close contacts of a patient suffering from meningococcal meningitis is", "exp": "Ref-KDT 6/e p729 Rifampicin and ciprofloxacin are used for the prophylaxis of meningococcal meningitis", "cop": 1, "opa": "Rifampicin", "opb": "Dapsone", "opc": "Erythromycin", "opd": "Amikacin", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "658bc4c5-2497-4841-b27d-034913175a9e", "choice_type": "single"} {"question": "Sutural separation seen in", "exp": "Diastatic fracture or sutural fracture: Suture separation is called a diastatic fracture. Penetrating and performing fracture: They are fractures produced by penetrating objects like a bullet, pointed sharp weapon, sword or dagger. Fracture which is having an entry and an exit is called a performing fracture. Cut fracture Skull may be subjected to cut injuries when a heavy cutting weapon is used. The cut injury may enter the skull cavity and injure the brain. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 164", "cop": 1, "opa": "Diastatic fracture", "opb": "Penetrating fracture", "opc": "Cut fracture", "opd": "Performing fracture", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "14b164c6-4bb8-486b-985c-3a1779b21da6", "choice_type": "single"} {"question": "Implantation occurs at the stage of", "exp": "C i.e. Blastocyst- Barrier is provided by fusion / feilin (not Ach)Q. Fusion reduce the membrane potential of ovum that prevents polyspermy by not allowing the others sperms to enter.- Morula is a 16 cell stage, surrounded by zona pellucida. Barrier is provided by fusiotVfetilin.QImplantation occurs at the stage of blasto cystQ.", "cop": 3, "opa": "Zygote", "opb": "Morula", "opc": "Blastocyst", "opd": "Primary villi", "subject_name": "Anatomy", "topic_name": null, "id": "1dae4806-29f9-44f3-9769-f574c41941aa", "choice_type": "single"} {"question": "Function of hepatic stellate cells are", "exp": "The hepatic cells are of mesenchymal origin , found in space of Dessie. The stellate cells play a role in the storage and metabolism of vitamin A and are transform into collagen producing myofibroblast when there is inflammation and Fibrosis of liver. Refer 9/e p436", "cop": 1, "opa": "Vitamin A storage", "opb": "Formation of sinusoids", "opc": "Increase blood perfusion", "opd": "Phagocytosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0bc5a266-8437-4fcc-b05c-9450e25f1bd3", "choice_type": "single"} {"question": "Tendon of Todaro connects", "exp": "Tendon of Todaro is a pa of Koch's triangle Base: ostium of coronary sinus Superior boundary: tendon of Todaro connects central fibrous body. Inferior boundary: septal cusp of tricuspid value. Apex: bundle of his & AV node.", "cop": 1, "opa": "Coronary sinus to tricuspid valve annulus", "opb": "Ridge of muscle connecting IVC and SVC", "opc": "Valve in opening of IVC", "opd": "Raised interatrial ridge", "subject_name": "Anatomy", "topic_name": "CVS Embryology", "id": "d3b2e5fc-b138-439e-88ec-a1e4d1db7041", "choice_type": "single"} {"question": "Holocrine glands are", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:204 Sebaceous glands The outer most cells are small and reston a basement membrane. the inner cells are larger more rounded and filled with lipid. this lipid is discharged by disintegration of the innermost cells that are replaced by proliferation of outer cells .the sebaceous glands are, therefore examples of holocrine glands", "cop": 2, "opa": "Sweat", "opb": "Sebaceous", "opc": "Mammary", "opd": "Pancreas", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a22172ee-8f52-48c3-a34a-2eb5ed44a0e2", "choice_type": "single"} {"question": "Calcitriol acts on", "exp": "Bioactive vitamin D or calcitriol is a steroid hormone that has long been known for its impoant role in regulating body levels of calcium Nuclear or cytosolic receptors include the binding sites for steroid hormones, thyroid hormones, vitamin D, and retinoic acids Ref-Goodman and Gillman 12th/e p1282", "cop": 2, "opa": "G protein coupled receptor", "opb": "Cytosolic receptor", "opc": "Intranuclear receptor", "opd": "Enzymatic receptors", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f761d7f8-7920-4ae5-a3fe-ce2103321cb4", "choice_type": "single"} {"question": "Following surgical removal of a firm nodular swelling in the right breast and exploration of the right axilla, on examination the patient was found to have a winged right scapula. Most likely this could have occurred due to injury to the", "exp": "C. i.e. Long thoracic nerve", "cop": 3, "opa": "Subscapular muscle", "opb": "Coracoid process of scapula", "opc": "Long thoracic nerve", "opd": "Circumflex scapular aery", "subject_name": "Anatomy", "topic_name": null, "id": "1804cf69-d6d1-4ced-94e8-6d7c6e367c5e", "choice_type": "single"} {"question": "Rotter's node is", "exp": "Ans: A Interpectoral nodes Interpectoral (Rotter's) lymph nodes - Small interpectoral lymph nodes located between pectoralis major & pectoralis minor muscles.", "cop": 1, "opa": "Interpectoral nodes", "opb": "Internal mammary LN", "opc": "Supraclavicular LN", "opd": "Infraclavicular LN", "subject_name": "Anatomy", "topic_name": null, "id": "1e7d9238-7829-407d-812b-d55f50b01443", "choice_type": "single"} {"question": "Nerve supply of deltoid is", "exp": "Anterior division of axillary nerve supplies most pa of the deltoid muscle.Posterior division of axillary nerve supplies the posterior fibres of deltoid muscle.B D Chaurasia 7th edition Page no: 180", "cop": 1, "opa": "Axillary", "opb": "Musculocutaneous", "opc": "Median", "opd": "Radial", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "65861a5d-42ba-4632-8ece-d0e7a73dc934", "choice_type": "single"} {"question": "Variant of Giant cell tumor is", "exp": "GCT is adult counterpa of chondroblastoma. Chondroblastoma is an epiphyseal tumor which occurs in 2nd decade while GCT is an epiphyseal tumor which occurs in adults Refer https ://emedicine. Medscape.com/aicle/125449-overview", "cop": 4, "opa": "Ossifying fibroma", "opb": "Non Ossifying fivroma", "opc": "Osteosarcoma", "opd": "Chondtoblastoma", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "a3e63920-b0ae-425b-a3a8-d04245224ffe", "choice_type": "single"} {"question": "A drug that blocks the uptake of dopamine and norephinephrine into presynaptic Nerve terminals and also block sodium channels in the axonal membrane is", "exp": "Ref-KDT 6/e p117 It is a local anaesthetic agent(act by inhibiting Na+ channel in the axonal membrane) that also possess indirect sympathomemtic activity", "cop": 1, "opa": "Cocaine", "opb": "Ephedrine", "opc": "Imipramine", "opd": "Floxentine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "e49e4a9b-449e-41c3-8137-f7984eed9c90", "choice_type": "single"} {"question": "Treatment of choice in Choledochal cyst is", "exp": "Treatment of Choledochal cyst Type I : Roux-en-Y hepaticojejunostomy Type II: Excision with T-tube REPAIR, Roux-en-Y hepaticojejunostomy Type III: Endoscopic sphincterectomy and cyst unroofing Type IVA: Hepatic resection for localised disease, Liver transplantation for diffuse diseases Type IVB: Transduodenal sphicteroplasty and Roux-en-Y hepaticojejunostomy Type V: Hepatic resection for localised disease, Liver transplantation for diffuse disease Ref: Sabiston 20th edition Pgno :1511", "cop": 1, "opa": "Roux-en-Y hepaticjejunostomy", "opb": "Cystojejunostomy", "opc": "Choledochoduodenostomy", "opd": "Choledochojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "66e684a6-3b93-4cd6-b81d-3bf914a3b5c5", "choice_type": "single"} {"question": "Buccal branch of facial nerve suppplies", "exp": null, "cop": 1, "opa": "Orbicularis oris & buccinator muscle", "opb": "Buccinator muscle", "opc": "Buccinator and superior constrictor muscle", "opd": "Buccinator and quadrates labii superioris muscle", "subject_name": "Anatomy", "topic_name": null, "id": "164a32c1-bcf0-45a5-a94c-cf7f4d238d9e", "choice_type": "single"} {"question": "Most common primary malignant tumor of liver in adult is", "exp": "Refer Robbins page no 869", "cop": 3, "opa": "Squamous cell carcinoma", "opb": "Hepatoblastoma", "opc": "Hepatocellular carcinoma", "opd": "Hepatoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a35691bd-a220-4473-bf0a-a89d016a3696", "choice_type": "single"} {"question": "The nerve that supplies the marked structure", "exp": "marked structure is Levator scapulae Nerve supply C5 Dorsal scapular nerve supplies Levator scapulae and Rhomboids major/ remarks : brachial plexus is repeat topic ref : GRAYS ANATOMY AND BD CHAURASIA", "cop": 4, "opa": "Dorsal rami of CI", "opb": "Suprascapular", "opc": "subscapular", "opd": "dorsal scapular", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cb7f3465-6507-43ec-a093-f4632be4c6a2", "choice_type": "single"} {"question": "Structures passing through superior orbital fissure", "exp": "superior orbital fissure * lateral pa lacrimal and frontal nerves, trochlear nerve, superior ophthalmic vein, meningeal branch of lacrimal aery, anastomotic branch of middle meningeal aery, which anastomoses with recurrent branch of lacriamal aery. * middle pa Upper and lower divisions of oculomotor nerve, nasociliary nerve, abducent nerve *medial pa Inferior ophthalmic vein .sympathetic nerve from plexus around internal carotid aery \"\" Ref BDC volume 3; 6th edition pg 56", "cop": 1, "opa": "Cranial nerve VI", "opb": "Cranial nerve I", "opc": "Cranial nerve II", "opd": "Ophthalmic nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1f8fab15-80e8-4ed7-a0bd-1a67405babee", "choice_type": "single"} {"question": "The palatal muscle that ends in a tendon that hooks around the hamulus and is inserted in the palate is the", "exp": null, "cop": 2, "opa": "Palatoglossus", "opb": "Tensor veli palatini", "opc": "Levator veli palatini", "opd": "Palatopharyngeus", "subject_name": "Anatomy", "topic_name": null, "id": "2571827a-de16-4fc0-9de6-cb58241b8c9d", "choice_type": "single"} {"question": "Struther's ligament is another name for", "exp": "Struther's ligament is another name for Third head of Coracobrachialis. Median nerve runs below the ligament and undergoes compression and leads to Struther's syndrome.", "cop": 4, "opa": "Radial collateral ligament of Elbow joint", "opb": "Ulnar collateral ligament of Elbow joint", "opc": "Third head of Brachialis", "opd": "Third head of Coracobrachialis", "subject_name": "Anatomy", "topic_name": null, "id": "cbf7b8a8-cbb1-4702-ad9f-32f966564e13", "choice_type": "single"} {"question": "The vertebral artery", "exp": "The vertebral artery is a branch of first part of subclavian artery. It lies posterior to inferior thyroid artery. It passes posterior to lateral mass of atlas.", "cop": 3, "opa": "Arises from the second part of subclavian artery , from behind scalenus anterior", "opb": "Lies anterior to inferior thyroid artery", "opc": "Passes through the C6 foramen transversarium", "opd": "Passes anterior to the lateral mass of atlas and then enters the foramen magnum", "subject_name": "Anatomy", "topic_name": null, "id": "ce858d63-60d8-404f-86a0-b8c5d86e90d3", "choice_type": "single"} {"question": "Creola bodies are seen in", "exp": "Refer ribbons 9/e p682 Creola bodies are a histopathologic finding indicative of asthma. Found in a patient's sputum, they are ciliated columnar cells sloughed from the bronchial mucosa of a patient with asthma. Other common findings in the sputum of asthma patients include Charcot-Leyden crystals, Curschmann's Spirals, and eosinophilsCreola bodies are a histopathologic finding indicative of asthma. Found in a patient's sputum, they are ciliated columnar cells sloughed from the bronchial mucosa of a patient with asthma. Other common findings in the sputum of asthma patients include Charcot-Leyden crystals, Curschmann's Spirals, and eosinophils", "cop": 1, "opa": "A. Bronchial asthma", "opb": "B. Emphysema", "opc": "C. Chronic bronchitis", "opd": "D. Bronchiectasis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "1bd56cd7-34c1-4966-816d-c13749041a25", "choice_type": "single"} {"question": "Hyperbaric oxygen is useful in", "exp": "Hyperbaric oxygen is currently considered a primary treatment modality for carbon monoxide poisoning, cerebral aerial gas embolism, osteoradionecrosis, decompression sickness, and clostridial gas gangrene. It is also considered an adjunctive therapy for acute exceptional blood loss anemia, acute thermal burns, compromised skin grafts or skin flaps, crush injury, compament syndrome, necrotizing soft-tissue infections, non-clostridial gas gangrene, radiation tissue damage, refractory osteomyelitis, selected problem wounds, and intracranial abscesses. Treatment of frostbite injuries with HBO is considered experimental. The treatment protocol for frostbite includes rapid rewarming, close observation, elevation and splinting daily hydrotherapy, and serial debridements.- Ref : Bailey & Love 25/e p39, (24/e p124)", "cop": 4, "opa": "Tetanus", "opb": "Frostbite", "opc": "Vincent's angina", "opd": "Gas gangrene", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f73db622-4926-4cfc-a927-23294a52a3cc", "choice_type": "single"} {"question": "Plasma cells", "exp": "Ref Robbins 8/e p183_184;7/e p82;9/e p191 Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that originate in the bone marrow and secrete large quantities of proteins called antibodies in response to being presented specific substances called antigens.", "cop": 2, "opa": "Contain nucleus", "opb": "Helps in the formation of antibody", "opc": "Are deficient in cytoplasm", "opd": "Are derived from T cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ef689396-e3fe-4799-89ff-27d913a9cbee", "choice_type": "single"} {"question": "Ureter develops from (2018)", "exp": "Ureteric bud arises from the lower pa of the mesonephric duct. ureter is derived from the pa of the ureteric bud. Ureteric bud also give rise to Renal pelvis,major and minor calyces, Renal papilae and collecting tubules Ref:- Inderbirsingh, pg num:-241,243, 246", "cop": 1, "opa": "A) Mesonephric duct", "opb": "B) Metanephric Mesoderm", "opc": "C) Metanephric Vesicles", "opd": "D) Pronephric vesicles", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9d5fd269-dfb4-4962-afb0-c40b3b78870d", "choice_type": "single"} {"question": "Blood flow in intervillous space at term", "exp": "A mature placenta has 500 m blood out of which 150 no is in the intervillous space and 350 ml in villi system. Ref: Datta Observe 9e pg 29.", "cop": 1, "opa": "150 ml", "opb": "250 ml", "opc": "300 ml", "opd": "500 ml", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "9a2e41fe-665c-485b-88c2-070c9f73ec38", "choice_type": "single"} {"question": "Samter's triad refers to the association of aspirin sensitive asthma and", "exp": "Samter's triad Asthma Asprin sensitivity Nasal polyposis Ref Harrison 19th edition pg 1680", "cop": 3, "opa": "Obesity", "opb": "Uicarla", "opc": "Nasal polyp", "opd": "Rhinosinusitis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "16c79e82-1679-4b87-ba99-12b1fabca8ac", "choice_type": "single"} {"question": "The antidiabetic drug with anorectic effect is", "exp": "Oral hypoglycemic agents Enhance insulin secretion Sulfonylureas ( K-ATP channel blockers )I - TolbutamideSafer in elderly & those prone to hypoglycemia, Controls postprandial hyperglycemia II - Glibenclamide, Glipizide, Gliclazide, GlimepiridePotent drugs with lower incidence of hypoglycemic attacks Meglitinide analogues Repaglinide, NateglinideStimulates insulin secretion & limits post prandial hypoglycaemiaGLP-1 receptor agonists Exenatide, Liraglutide Lowers post prandial hypoglycaemia , fasting blood glucose , HbA1c and body weight Produces anorectic effect DPP 4 inhibitors Sitagliptin, Vida gliptin, Saxagliptin, Alogliptin, LinagliptinBoosts postprandial insulin release, decreases glucagon secretion, lowers meal time & fasting blood glucose Overcome insulin resistanceBiguanide ( AMP-K activator )Metformin Suppresses hepatic gluconeogenesis, enhances insulin-mediated glucose uptake in skeletal muscle & fat, promotes peripheral glucose utilization Thiazolidinediones ( PPARg activator )Pioglitazone, Rosiglitazone, Troglitazone Suppresses hepatic gluconeogenesis, an activator of genes regulating fatty acid metabolism & lipogenesis in adipose tissue, lowers HbA1c and insulin levels Miscellaneous drugsa-glucosidase inhibitors Acarbose , Voglibose , Miglitol Reduces post prandial glycemia , lowers HbA1C levels Amylin analogue Pramlintide Delay gastric emptying, retard glucose absorption & promotes satiety Dopamine D2 receptor agonist Bromocriptine Suppresses glycemic peak, reduce body weight SGLT - 2 inhibitor Dapagliflozin, CanagliflozinProduces round the clock glucosuria, lowers blood glucose levels", "cop": 1, "opa": "Liraglutide", "opb": "Gliclazide", "opc": "Acarbose", "opd": "Chlorpropamide", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "fc5ba7c2-425e-4d0d-81af-67d294537de0", "choice_type": "single"} {"question": "Strawberry cervix is caused by", "exp": "Strawberry cervix is caused by Trichomonas vaginalis. Severe inflammation of the cervix with macular haemorrhages gives it a strawberry appearance and hence the name. Similar inflammation with haemorrhages on the vagina is called colpitis macularis.", "cop": 1, "opa": "Trichomonas vaginalis", "opb": "Neisseria", "opc": "Candidiasis", "opd": "Chlamydia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "41a45791-342c-46bb-a38d-b9d96d45c574", "choice_type": "single"} {"question": "Denver shunt is used in", "exp": "Denver shunt It is used for the relief of ascites due to chronic liver disease To prevent high occlusion rates as seen in Le-Veen shunt, a fuher development was the inseion of a chamber placed over the costak margin to allow digital pressure and evacuation of any debris within the peritoneovenous shunt Ref: Textbook of hepatology by Erwin kuntz Pgno :317", "cop": 1, "opa": "Ascites", "opb": "Dialysis", "opc": "Raised ICT", "opd": "Raised IOP", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "00aff8f9-fb7e-413a-9214-ec8a93d74565", "choice_type": "single"} {"question": "Most impoant component of Bishop score", "exp": "The most impoant component of bishop score is dilatation of cervix", "cop": 2, "opa": "Position", "opb": "Dilatation", "opc": "Station", "opd": "Effacement", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "8b5402cc-27db-429e-94d9-e59cd2ad2c82", "choice_type": "single"} {"question": "The vitelline vein forms the", "exp": "A i.e. Hepatic vein", "cop": 1, "opa": "Hepatic vein", "opb": "Azygos vein", "opc": "Inferior mesenteric vein", "opd": "Splenic vein", "subject_name": "Anatomy", "topic_name": null, "id": "f7c7db1c-bb51-47d9-838d-c7e298160652", "choice_type": "single"} {"question": "The ideal temperature of water to cool down the burned area is", "exp": "Cool the burn wound. This provides analgesia and slows the delayed microvascular damage that can occur after a burn injury. Cooling should occur for a minimum of 10 minutes and is effective up to 1 hour after the burn injury. It is a paicularly impoant first aid step in paial-thickness burns, especially scalds. In temperate climates, cooling should be at about 15degC, and hypothermia must be avoided Ref bailey and love 27e p620", "cop": 3, "opa": "5degc", "opb": "10degc", "opc": "15degc", "opd": "20degc", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a83fa456-c969-4350-be83-5e351b89720a", "choice_type": "single"} {"question": "The normal angle of the neck of the femur to shaft is approximately....", "exp": "The normal angle of the neck of the femur to the shaft is approximately 125deg. This is known as neck shaft angle or angle of inclination. This facilitates the movement at the hip joint, enabling the limb to move freely. Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 1348.", "cop": 2, "opa": "105deg", "opb": "125deg", "opc": "145deg", "opd": "115deg", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2e1bec36-a722-48ab-a5e3-fd341374c04d", "choice_type": "single"} {"question": "delirium in ICD 10 is calssified under", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref.International classiication of disorders, ICD 10 th edition", "cop": 1, "opa": "F00", "opb": "F10", "opc": "F20", "opd": "F30", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d9f2de8d-67a6-4773-a751-f4035e7192bf", "choice_type": "single"} {"question": "bulimia nervosa isassosiated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 2, "opa": "decreased sexual drive", "opb": "alkalosis", "opc": "obesity", "opd": "acidosis", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "5711defb-db55-4c7d-8ab9-9eef96560f16", "choice_type": "single"} {"question": "Popliteal aery is difficult to palpate because", "exp": "D i.e. Not superficial & does not pass over prominent bony structure", "cop": 4, "opa": "It is not superficial", "opb": "Does not pass over prominent bony structure", "opc": "Superficial but does not pass over prominent bony structure", "opd": "Not superficial & does not pass over prominent bony structure", "subject_name": "Anatomy", "topic_name": null, "id": "1e052dfe-68d2-4714-855f-6b44d4afacb4", "choice_type": "single"} {"question": "The testis descends the inguinal canal during...month.", "exp": "C i.e. 7th", "cop": 3, "opa": "5th", "opb": "6th", "opc": "7th", "opd": "8th", "subject_name": "Anatomy", "topic_name": null, "id": "36503675-efa0-46dc-976b-d41c2c6493d4", "choice_type": "single"} {"question": "Increase in height in first year is by", "exp": "Length at bih- 50 cms, while at the end of 1st year, it is 75 cms, i.e., height increases by 25cms, which will be 50% 50% of 50cms (at bih) will be 25cms, and by adding this 25cms to 50cms it'll account to 75 cms( at the end of 1yr) Ref: Nelson's 20th edition, pg 84-89", "cop": 2, "opa": "40%", "opb": "50%", "opc": "60%", "opd": "75%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e3f32ef7-e1ea-4ae0-8573-37b29887f941", "choice_type": "single"} {"question": "Nerve for adductor compament of thigh", "exp": "OBTURATOR NERVE:- Branch of lumbar plexus Nerve of adductor compament Arises from ventral division of ventral rami of L2,L3,L4 segments. It emerges on the medial border of psoas major muscle within the abdomen.It crosses the pelvic brim to run downwards and forwards on the lateral wall of pelvis to reach upper pa of obturator foramen. Terminates by dividing into anterior and posterior Divisions. BRANCHES:-Anterior division 1. Muscular branches: pectineus, adductor longus, adductor brevis,gracilis.2. Aicular: hip joint.3. Vascular and cutaneous: femoral aery.Posterior division 1. Muscular: obturator externus,adductor magnus(adductor pa)2. Aicular: knee joint 3. Vascular and cutaneous: popliteal aery. {Reference: BDC 6E pg no. 172}", "cop": 2, "opa": "Femoral nerve", "opb": "Obturator nerve", "opc": "Superior gluteal nerve", "opd": "Inferior gluteal nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "34c8177c-63d7-41f4-8115-0da53c9b60d9", "choice_type": "single"} {"question": "Catastrophic variant of Ehler Danlos syndrome is", "exp": "Ehlers danlos syndrome comprise group of clinically and genetically heterogeneous group of disorder that result from defects in synthesis or structure of fibrillar collagen. Ref Robbin's 9th/146", "cop": 4, "opa": "I", "opb": "II", "opc": "III", "opd": "IV", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "052c0c11-38a6-45a3-b8bd-ac715b3a7af3", "choice_type": "single"} {"question": "In the intraepthielial region of the mucosa of intestine the predominant cell population is that of", "exp": "IEL are6 a distinctive population of T cells dispersed among the luminal epithelial cells. paicularly in the small intestine there is a predominantly of CD8+T cells", "cop": 2, "opa": "B cell", "opb": "T cell", "opc": "Plasma cells", "opd": "Basopils", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "655de91c-95e0-4166-8a2a-d04c42d55729", "choice_type": "single"} {"question": "Palmar interossei is supplied by", "exp": "All palmar interossei are supplied by the deep branch of the ulnar nerve (C8, T1). Ref : B D Chaurasia's Human Anatomy, Seventh edition , volume 1 , pg. no, 124", "cop": 2, "opa": "Superficial branch of ulnar nerve", "opb": "Deep branch of ulnar nerve", "opc": "Superficial branch of medial nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "145de249-1e71-4b42-a68d-70241bb4fe01", "choice_type": "single"} {"question": "The distance of gastroesophageal junction from upper incisor is", "exp": "Oesophagus begins at the lower border of cricoid cailage (at the level of C5 veebrae)Q, passes through diaphragm at the level of T10 veebrae and ends in the abdomen at the cardiac orifice of stomach at the level of Tn veebrae. Its is 25 cm long.- Small aggregation of lymphoid tissue is present in submucosaQ near lower end (not mucosa) Circular muscle fibers of lower end of esophagus form physiological sphincter at cardioesophageal junction.Oesophagus don't have serous covering except over a sho length near its lower end.", "cop": 3, "opa": "15 cm", "opb": "25 cm", "opc": "40 cm", "opd": "60 cm", "subject_name": "Anatomy", "topic_name": null, "id": "7be63022-e17f-4153-b936-aa64667707d5", "choice_type": "single"} {"question": "Right superior intercostal vein drains into", "exp": "The right superior intercostal vein drains the 2nd, 3rd, and 4th posterior intercostal veins on the right side of the body. It flows into the azygos vein. The left superior intercostal veins drains the 2nd and 3rd posterior intercostal veins on the left side of the body. It drains into the left brachiocephalic vein B D CHOURASIAS HUMAN ANATOMY UPPER LIMB THORAX VOLUME, 1 SIXTH EDITION, page no,221", "cop": 2, "opa": "Brachiocephalic vein", "opb": "Azygos vein", "opc": "Inferior venacava", "opd": "Hemizygos vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "5c4e69f6-fa7a-483c-8dd7-2f8585a52c9d", "choice_type": "single"} {"question": "Haversian system is seen in", "exp": "* Microscopically, the bone is of five types, namely lamellar (including both compact and cancellous), woven, fibrous, dentine and cement. 1. Lamellar bone: Most of the mature human bones, whether compact or cancellous, are composed of thin plates of bony tissue called lamellae. These are arranged in piles in a cancellous bone, but in concentric cylinders (Haversian system or secondary osteon) in a compact bone. 2. Woven Bone: seen in fetal bone, fracture repair and in cancer of bone 3. Fibrous bone is found in young foetal bones, but are common in reptiles and amphibia. 4. Dentine and 5. Cement occur in teeth. * Compact bone ( coical bone) In shaft (diaphysis) of long bone - lamellae arranged to form Haversian system - Bone marrow Yellow which stores fat after pubey. It is red before pubey - Hard and ivory-like * Cancelled bone spongy, or trabecular bone - In the epiphyses of long bone - arranged in a meshwork, so Haversian systems are not present - bone marrow red, produce RBCs, granular series of WBC and platelets - spongy * Nails are made of a tough protective protein called keratin - consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it (Reference : BDC Handbook of General Anatomy , 5th edition, pg 39)", "cop": 1, "opa": "Coical bone", "opb": "Cancellous bone", "opc": "Teeth", "opd": "Nail", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "23e42325-bd2d-49cf-a4c4-c502c82aa672", "choice_type": "single"} {"question": "Not a predisposing factor for cholangiocarcinoma", "exp": "Choledocholithiasis, not the cholelithiasis is a risk factor for cholangiocarcinoma Risk factors for cholangiocarcinoma Choledochal cyst Primary sclerosing cholangitis Ulcerative colitis. RPC or hepatolithiasis. Biliary enteric anastomosis HBV, HIV, HCV Choledocholithiasis Clonorchis sinensis and opisthorchis viverrini Cirrhosis Radon Asbestos, Nitrosamines, Dioxib(AND). Diabetes, Obesity, OCP's, smoking, Thorotrast, Isoniazid(DOSTI) Ref: Sabiston 20th edition Pgno :1514", "cop": 2, "opa": "Asiatic cholangiohepatitis", "opb": "Cholelithiasis", "opc": "Ulcerative colitis", "opd": "Choledochal cyst", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "50da022f-9d30-4309-b090-333cef491ed7", "choice_type": "single"} {"question": "Cranial nerve related to apex of petrous temoporal bone", "exp": "Cranial nerve 5 & 6 are related to apex of petrous bone.\nOnly 1st & 2nd cranial nerves do not arise from brain stem and so do not pass through posterior-cranial fossa. And all other C.N (i.e. 3rd to 12th) pass through posterior cranial fossa.\nTrochlear (4th) nerve is the only cranial nerve to emerge dorsally from the brain stem & has longest infra cranial course and most slender cranial nerve (in terms of axons it contains)", "cop": 3, "opa": "VIII", "opb": "VII", "opc": "VI", "opd": "IX", "subject_name": "Anatomy", "topic_name": null, "id": "e6847ec1-57cd-4cc4-b390-5a8c242075ee", "choice_type": "single"} {"question": "In erect posture commonest site of foreign body in bronchus is", "exp": "From Schwa, 7/e- \"The most common anatomic location for a foreign body is the right main stem bronchus or the . lower lobe.\" \" The right main stem bronchus is wider, shoer and veically placed, and therefore the posterior segments of the right upper lobe (if the pt. aspirated while supine) are anatomically susceptible to aspiration pneumonia. The superior segments of the right lower lobe and left lower lobe (if the pt. supine) are also susceptible to aspiration pneumonia. These three segments are often referred to as the aspiration segments of the lung. The basilar segments of both lungs are susceptible to aspiration if the pts. aspirates while erect or sitting up.\" Aspiration in Supine Position : RL upper lobe - posterior segment Rt. lower lobe - superior segment Lt. lower lobe - superior segment Aspiration in sitting or erection position Rt. basilar segments (of lower lobe). Ref : Schwaz 9/e p1420", "cop": 1, "opa": "Right posterior basal", "opb": "Right anterior basal", "opc": "Lateral basal", "opd": "Medial basal", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "cb20e12b-9f00-4376-9901-ac3864b973f1", "choice_type": "single"} {"question": "Hemiazygous vein crosses left to right at the level", "exp": "Hemiazygos vein crosses from left to right at the level of T8, after piercing the left crus of diaphragm while ascending.", "cop": 1, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "T6", "subject_name": "Anatomy", "topic_name": null, "id": "58154b06-bd9a-4ed7-9a93-e1cf06d68a81", "choice_type": "single"} {"question": "Diagnosis of Hodgkin's disease is confirmed by", "exp": "Ref : Bailey & Love 25/e p945", "cop": 3, "opa": "CT scan", "opb": "Bone marrow biopsy", "opc": "Lymph node biopsy", "opd": "Lymphangiography", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b1e3bc9f-c826-4484-8929-514b71d96699", "choice_type": "single"} {"question": "Hyperkalemia means more than", "exp": "Normal plasma K+ concentration is b/w 3.5 & 5.0 mEq/L. Hyperkalemia is defined as a plasma potassium level more than 5.5 mEq/L Hypokalemia: plasma K+ < 3.5 mEq. Severe hyperkalemia is K+ > 6.0 mEq. > 8.0 mEq- Causes diastolic arrest (Systolic arrest seen when Ca > 13 mg %) Causes of hyperkalemia: Pseudo hyperkalemia: Fist clenching, narrow bore needle, cooling of sample, TLC |, Platelet |, RBC| Acidosis: Trans-cellular shift CKD/AKI Aldosterone | - Addison disease, histoplasmosis, HIV, Waterhouse Frederickson syndrome Gordon syndrome - + gain of function of NaCl cotranspo ECG changes in Hyperkalemia - Tall tented T wave ST elevation Broad QRS If > 8.0 mEq: SINE WAVE PATTERN is seen. Treatment: Antagonism: Calcium gluconate , calcium chloride Redistribution: Insulin drip with 50% dextrose; salbutamol nebulization Removal of potassium: Furosemide, resin sodium polystyrene sulphonate etc", "cop": 2, "opa": "4.5 mEq/l", "opb": "5.5 mEq/l", "opc": "7.5 mEq/l", "opd": "10.5 mEq/l", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "d4d14ed3-705b-4db5-be45-b3f0d6d06666", "choice_type": "single"} {"question": "Multiple intrahepatic bile duct dilation with bile lakes and concurrent sepsis is suggestive of", "exp": "Caroli's disease Clinical features : Symptoms include cholangitis (64%), poal hypeension (22%) and abdominal pain(18%) More common in males Septa containing poal veins protrude into the lumen of the ecstatic bile ducts (central dot sign) The main and often the only symptom of bacterial cholangitis secondary to caroli's disease is fever without abdominal pain and jaundice Frequent episodes of cholangitis indicates poor prognosis Most stones are pigmented in caroli's disease Ref: Sabiston 20th edition Pgno :1511", "cop": 1, "opa": "Caroli's disease", "opb": "Watson Algali syndrome", "opc": "Primary sclerosing cholangitis", "opd": "Klatskin tumor", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "f6b9e281-b40f-4e89-b2ea-360b6c56d75a", "choice_type": "single"} {"question": "Mediastinal surface of right lung is related to", "exp": "> (because hea & its blood vessels should be preferred first as an answer as they cause direct impression on lungs). * mediastinal surface of Right lung contains Left lung contains Hea (right atrium) Superior vena cava Inferior vena cava Azygos vein Esophagus Right subclan aery & vein arch over and are related to superior lobe of right lung. Hea (left ventricle) Aoic arch Thoracic aoa Esophagus Left subclan aery & vein arch over & related to superior lobe of left lung. fig;- major structure related to mediastinal surface of right lung Right lymphatic duct - not related to lung Thoracic duct - related to left lung mediastinal surface But they do not put great impression on lungs * Trachea is more towards right lung * Esophagus is more towards left lung", "cop": 1, "opa": "Azygos vein", "opb": "Right lymphatic duct", "opc": "Aoa", "opd": "Trachea", "subject_name": "Anatomy", "topic_name": "Surfaces and Grooves", "id": "9e0c96eb-5b2b-43ec-93ca-de82396d5cd1", "choice_type": "single"} {"question": "A paitent met an accident with a car and has been in `deep coma' for the last 15 days. The most suitable route for the administration of protein and calories is by", "exp": "Unless the gastrointestinal tract is non-functional, its use for nutritional suppo is preferable to the use of either the central or a peripheral venous route. However, in a patient who is comatose either nasogastric feeding or feedings through a gastrostomy tube may lead to vomiting and aspiration. This problem can be avoided by using a nasoenteric tube with the tip placed in the jejunum under fluoroscopic or endoscopic control. Alternatively, a catheter may be placed directly into the proximal jejunum through a small upper abdominal incision", "cop": 1, "opa": "Jejunostomy tube feeding", "opb": "Gagstrotomy tube feeding", "opc": "Nasogastric tube feeding", "opd": "Central venous hyperalimentation", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "956ddc2a-bdfd-464a-bda1-877ee02040de", "choice_type": "single"} {"question": "Posterior boundary of Epiploic foramen is formed by", "exp": "Posterior boundary of Epiploic foramen is formed by Inferior venacava, T12 Vertebra and Right Suprarenal gland", "cop": 2, "opa": "L1 vertebra", "opb": "T12 Vertebra", "opc": "T11 Vertebra", "opd": "T10 Vertebra", "subject_name": "Anatomy", "topic_name": null, "id": "d85982bd-cac6-47a5-977d-8a2f58dd263d", "choice_type": "single"} {"question": "Punishment for penetrative sexual assault under POSCO act is", "exp": "Protection of Children from Sexual Offences Act(POSCO) According to this act, child is a person below 18 years of age. Punishment for penetrative sexual assault : shall be punished with imprisonment for 7 years which may be extended for life and also liable for fine. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 307", "cop": 2, "opa": "5 years", "opb": "7 years", "opc": "10years", "opd": "12 years", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "cfe5efd9-ac23-4ba9-b604-727b2189ae32", "choice_type": "single"} {"question": "1st spinal nerve is related to", "exp": "The anterior primary ramus of C1 joins with hypoglossal nerve, which distributes the motor fibres to the geniohyoid and thyroid muscles. C1 is the first spinal nerve which is unique in that it contains only motor fibres. (Ref: Vishram Singh textbook of clinical neuroanatomy, second edition pg 107)", "cop": 3, "opa": "Glossopharyngeal", "opb": "Vagus", "opc": "Hypoglossal", "opd": "Facial", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "0b348177-4ffb-49e3-915e-bb350902ba7e", "choice_type": "single"} {"question": "Drug remains in the body after three lives is", "exp": "Cp - > Cp/2 in 1 half-life i.e. 50.0 % lost 50.0 % Cp - > Cp/4 in 2 half-lives i.e. 25.0 % lost 75.0 % Cp - > Cp/8 in 3 half-lives i.e. 12.5 % in body and lost 87.5 % Cp - > Cp/16 in 4 half-lives i.e. 6.25 % lost 93.75 % Cp - > Cp/32 in 5 half-lives i.e. 3.125 % lost 96.875 % Cp - > Cp/64 in 6 half-lives i.e. 1.563 % lost 98.438 % Cp - > Cp/128 in 7 half-lives i.e. 0.781 % lost 99.219 % Ref-KDT 7/e p30", "cop": 1, "opa": "12.50%", "opb": "87.50%", "opc": "75%", "opd": "94%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c95d9263-1167-4d2f-b0f7-66ad2194625c", "choice_type": "single"} {"question": "Osteomyelitis in sickle cell anemia is due to DELETE", "exp": "Most common cause of osteomyelitis in sickle cell anemia is salmonella Refer Maheshwari 6tg/e p 168", "cop": 1, "opa": "Salmonella", "opb": "Streptococcus", "opc": "Hemophilus", "opd": "Neisseria", "subject_name": "Anatomy", "topic_name": null, "id": "ecef7a98-d23c-4870-9e3b-ea64a7bb31d0", "choice_type": "single"} {"question": "Ureters is lined by", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:318", "cop": 4, "opa": "Cuboidal epithelium", "opb": "Columnar epithelium", "opc": "Squamous epithelium", "opd": "Transitional epithelium", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9defb90a-bd44-449c-aa72-bd8dbd0b0f40", "choice_type": "single"} {"question": "E cadherin gene deficiency is seen in", "exp": "Ref Robbins 9/e p291 Cadherins is derived from the calcium dependant adherence protein.It paicipate in interactions between cells of same type.The linkage of cadherins with the cytoskeleton occurs through the catenins.The cell to cell interactions mediated by cadherins and catenins play a major role in regulating cell motility, proliferation,and differentiation and account for the inhibition of cell proliferation that occurs when cultured normal cells contact each other ( contact inhibition) Reduced functions of E cadherins is associated with ceain types of breast and gastric cancer", "cop": 1, "opa": "Gastric cancer", "opb": "Intestinal cancer", "opc": "Thyroid cancer", "opd": "Pancreatic cancer", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9077289d-d066-4b3b-aaa5-9116a12a5768", "choice_type": "single"} {"question": "Magnan's symptom', 'crack lung' and 'crack dancing' are seen in chronic use of", "exp": "Chronic use of cocaine The face will be pale, eyes sunken and marked evacuation, black discoloration of teeth and involuntary tooth grinding(bruxism) There may be persistent rhinitis nasal erosion with perforation Males suffer from loss of libido, impotence and infeility. Females suffer from galactorrhoea, amenorrhoea, and infeility. The person may suffer from paranoid or depressive psychosis, hallucinations, delusions, convulsions, and delirium due to degenerative changes in CNS The person may have tactile hallucination that insects are crawling under the skin. This is called Magnan's symptom or Cocaine bugs/ formication. Crack lung refers to hypersensitivity, bronchospasm, dysnoea, and pneumonia occurs as a result of cocaine smoking. crack dancing refera to extra pyramidal signs and symptoms after cocaine intake. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 485", "cop": 3, "opa": "Alchol", "opb": "Canabis", "opc": "Cocaine", "opd": "Barbiturates", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "8faf3bea-d09e-42ed-b8ca-91792c3d4a51", "choice_type": "single"} {"question": "Ascending pharyngeal aery is branch of", "exp": "*Ascending pharyngeal aery is a small branch that arises from the medial side of the external carotid aery. *It arises very close to the lower end of external carotid aery. *It runs veically upwards between the side walls of the pharynx, and the tonsil, medial wall of the middle ear and, the auditory tube. *It also sends meningeal branches into the cranial cavity through the foramen lacerum, the jugular foramen, and the hypoglossal canal. Ref: BDC 6th edition pg 103 ,230", "cop": 4, "opa": "Arch of aoa", "opb": "Inferior thryroid aery", "opc": "Superior thryroid aery", "opd": "Ext. Carotid Aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f352bed8-f0a8-46f6-8315-ae73f7eabd1d", "choice_type": "single"} {"question": "Medial boundary of Cubital fossa is", "exp": "CUBITAL FOSSA:-Triangular hollow in front of the elbow. Boundaries:-1. Lateral:- medial border of brachioradialis.2. Medial: lateral border of pronator teres.3. Base: imaginary horizontal line joining two epicondyles of the humerus.4. Apex: It is directed downwards, and is formed by the area where brachioradialis crosses the pronator teres muscle.5. Floor: brachialis (upper pa) Contents: medial to lateral 1. Median nerve 2. Brachial aery.3. Biceps tendon.4. Radial nerve. mnemonic: MBBR Brachial pulse- recording BPMedial cubital vein- collect blood samples & iv injection. REF: BD Chaurasia 7th edition page no: 97.", "cop": 2, "opa": "Brachioradialis", "opb": "Pronator teres", "opc": "Supinator", "opd": "Brachialis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "25c61070-1246-411f-b009-5006a86b8e44", "choice_type": "single"} {"question": "Drug of choice in PSVT is", "exp": "Table 276-3 Adenosine 6-18 mg (rapid bolus) N/A Terminate reentrant SVT involving AV node --ref Harrison 20th edition pg 1435", "cop": 4, "opa": "Amiodarone", "opb": "Lingnocaine", "opc": "Quinidine", "opd": "Adenosine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1e132a9f-68d7-4625-b09b-f1ab3a4684af", "choice_type": "single"} {"question": "Pain in early labor is limited to dermatomes", "exp": "In early stages of labor pain is mainly uterine in origin . Distributed along the cutaneous nerve distribution T10 - L1 In later stages pain is due to dilatation of cervix referred to back through sacral plexus", "cop": 1, "opa": "T10 - L1", "opb": "S1- S3", "opc": "L4- L5", "opd": "L2- L3", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "62151cc8-47d6-4379-aca9-d83ffd0e390e", "choice_type": "single"} {"question": "Least common site for lung abcess is", "exp": "About the site of lung abscess associated with aspiration . \"Because of the effect of gravity, foci of infection tend to develop in the subpleural regions of the superior segments of the lower lobes and in the posterior segments of the upper lobes. The right lung is involved more frequently, presumably because of the less acute angle of the right main bronhus. thus the right upper and lower lobes are the most commonly affected, followed by the left lower lobe and right middle lobe.\" Ref : Schwaz 9/e p.549", "cop": 4, "opa": "Right upper lobe", "opb": "Right lower lobe", "opc": "Left lower lobe", "opd": "Left upper lobe", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "84766a38-b1f6-46d6-b65e-3b3c2b17efeb", "choice_type": "single"} {"question": "The normal ratio of CD4to CD8 is", "exp": "Ref Robbins 9/e p190-191 A normal CD4/CD8 ratio is 2.0, with CD4lymphocytes equal to or greater than 400/mm3 and CD8 lymphocytes equal to 200 to 800/mm3. If your ratio is higher than 2, it means your immune system is strong and you may not have HIV. If your ratio is less than 1, you may have: HIV.", "cop": 2, "opa": "1:01", "opb": "2:01", "opc": "8:01", "opd": "10:01", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ec140706-21e3-4f0c-ba1b-6710bc84409a", "choice_type": "single"} {"question": "Microcephaly is seen in\nBeckwith hypoglycaemic syndrome\nFanconi syndrome\nDown syndrome\nAchondroplasia", "exp": "A condition in which a baby's head is significantly smaller than expected, often due to abnormal brain development. Causes of microcephaly include infections, malnutrition or exposure to toxins.\nSymptoms vary and include intellectual disability and speech delay. In severe cases, there may be seizures and abnormal muscle functionality.", "cop": 2, "opa": "I and iv", "opb": "I and ii", "opc": "ii and iii", "opd": "ii and iv", "subject_name": "Anatomy", "topic_name": null, "id": "30403ad9-b7de-441a-ab2d-987652ead942", "choice_type": "single"} {"question": "Base of the hea is formed by", "exp": "Base of hea is formed by left atrium and the small pa of right atrium. BD CHAURASIA&;S HUMAN ANATOMY.VOLUME 1. 6TH EDITION.PAGE NO 253", "cop": 3, "opa": "Right atrium", "opb": "Right ventricle", "opc": "Left atrium", "opd": "Left ventricle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "39ef064e-c512-4dcf-9109-a0eec8e41044", "choice_type": "single"} {"question": "A patient presented with a 1 X 1.5 cms growth on the lateral border of the tongue. The treatment indicated would be", "exp": "Radiation therapy may be curative in early cancer (T1 and some T2) and may preserve maximal normal anatomy and function. Brachytherapy allows delivery of a large radiation boost to the primary tumour bed", "cop": 3, "opa": "Chemotherapy", "opb": "Laser ablation", "opc": "Interstitial brachytherapy", "opd": "External beam radiotherapy", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "66666316-318b-4233-9bfe-b018e18939ef", "choice_type": "single"} {"question": "Afferent component in corneal reflex is mediated by", "exp": "Ophthalmic nerve carries sensory fibres from the structures derived from frontonasal process. In injury to ophthalmic nerve, there is loss of corneal blink reflex. This reflex is mediated by V1 which is afferent pathway and VII nerve which subserves as efferent pathway. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3.", "cop": 2, "opa": "Optic nerve", "opb": "Ophthalmic nerve", "opc": "Facial nerve", "opd": "Occulomotor nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "cda87340-168e-4ca1-ade1-a6128c55d106", "choice_type": "single"} {"question": "Inheritance of gardener syndrome is", "exp": "It is sub type of familial adenomatosis polyposis inherited as an autosomal dominant disorder Gardener syndrome ;intestine polyps +epidermal cysts+fibromatosis+osteomas Refer 8/e p816", "cop": 2, "opa": "A. Autosomal recessive", "opb": "B. Autosomal dominant", "opc": "C. X-linked dominat", "opd": "D. X-linked recessive", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b0fc9b8d-04d1-4ad6-b869-c51d1c67b62b", "choice_type": "single"} {"question": "Superior vena cava opens into right atrium at the level of", "exp": "SVC open into right atrium at the level of T5 . Ref - BDC 6th edition vol 1 pg272", "cop": 4, "opa": "T1", "opb": "T3", "opc": "T4", "opd": "T5", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "cb1f95cb-70c7-43e4-9102-e566d5072084", "choice_type": "single"} {"question": "The gold standard for diagnosis of pulmonary embolism", "exp": "Pulmonary embolism The risk factors for pulmonary embolism are the risk factors for thrombi formation within the venous circulation.The most common site for DVT: Calf veinsMost common source of pulmonary emboli: proximal vein of lower extremity (femoropopliteal and iliac vein)Calf venous thrombosis is itself associated with a low risk for embolism but when the thrombosis progresses proximally to involve the larger veins then the risk factors become very highClinical featuresFactors for clinical assessment of pulmonary embolismSymptoms: dyspnoea (MC), chest pain, hemoptysis, coughSigns: tachypnoea (MC), fever, unilateral leg swelling, wheeze, pleural friction rubClinical signs and symptoms of DVTAn alternative diagnosis is less likely than pulmonary embolismHea rate > 100/minImmobilization or previous surgery in 4 weeksPrevious DVT/PEHemoptysisMalignancy (on treatment, treatment in past 6 months)ECG changesDiagnosisFeatures suggesting acute right hea strain on ECG occur relatively infrequently, these include :Acute right axis detionP pulmonaleRight bundle branch blockInveed T wavesST segment changeECG changes highly predictive (but found in <12% pts) S wave in lead IQ wave in lead IIIInveed T wave in lead III (S1Q3T3)S wave in lead I, II, and III (S1S2S3)D-dimer is an excellent screening test for the diagnosis of PE Best investigation when there is clinical suspicion of PE: Multidetector Contrast CTLung scanning is now a second line diagnostic test for PE.Pulmonary angiography is the gold standard for the diagnosis of PE ECG changesDiagnosisFeatures suggesting acute right hea strain on ECG occur relatively infrequently, these include :Acute right axis detionP pulmonaleRight bundle branch blockInveed T wavesST segment changeECG changes highly predictive (but found in <12% pts) S wave in lead IQ wave in lead IIIInveed T wave in lead III (S1Q3T3)S wave in lead I, II, and III (S1S2S3)D-dimer is an excellent screening test for the diagnosis of PE Best investigation when there is clinical suspicion of PE: Multidetector Contrast CTLung scanning is now a second line diagnostic test for PE.Pulmonary angiography is the gold standard for the diagnosis of PE (Refer: Harrison's Principle of Internal Medicine, 18thedition, pg no- 2174)", "cop": 2, "opa": "Chest X-ray", "opb": "Pulmonary angiography", "opc": "Ventilation perfusion scintiscan", "opd": "CECT", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "68aad833-a180-403b-a9b5-2da794eefeb3", "choice_type": "single"} {"question": "F 30 in ICD 10 denotes", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref. International classification of mental disorders, 10 th edition", "cop": 1, "opa": "mood disorders", "opb": "anxiety disorders", "opc": "substance use disorders", "opd": "psychotic disorders", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "48cc816d-81c7-4697-bfd5-e8c4afef56ff", "choice_type": "single"} {"question": "Axillary aery is divided into 3 pas by", "exp": "Axillary aery is divided into 3 pas by Pectoralis minor The 3 pas are Superior thoracic aery Thoracoacromial trunk Subscapular aery Ref : BD Chaurasia Human Anatomy 5e vol 2 pg 55.", "cop": 3, "opa": "Pectoralis major", "opb": "Clavicle", "opc": "Pectoralis minor", "opd": "Teres minor", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "cf3e7963-83a8-49db-87e5-2fa3486735fa", "choice_type": "single"} {"question": "Azygos lobe is found", "exp": "Azygous lobe is seen in lungs . Ref - BDC 6thedi vol 1 pg236", "cop": 3, "opa": "Hea", "opb": "Spleen", "opc": "Lung", "opd": "Pancreas", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "a299ec1b-a042-40ab-802d-188a3af7c282", "choice_type": "single"} {"question": "Trachoma is characterized by the presence of", "exp": "Trachoma - Chronic keratoconjunctivitis Affects the superficial epithelium of conjunctiva and corneaCaused by Chlamydia trachomatis (TRIC) agentA, B, Ba, C - Hyperendemic trachomaD to K - Neonatal and adult inclusion conjunctivitisTrachoma Disease spectrumConjunctivaCorneaSigns Congestion of upper tarsal conjunctivaFollicles over upper tarsal or palpebral conjunctiva, lower fornix, plica semilunaris Arlt's line - linear scar in sulcus Sub tarsalisPapillary hyperplasia Concretions Superficial keratitis Herbe follicles Pannus - infiltration, and vascularization of the cornea Corneal ulcer Herbe pits Corneal opacity SequelaeConcretions Pseudocyst Xerosis SymblepharonTrichiasis Corneal opacity Ectasia Corneal xerosis Corneal pannus Epidemiological criteria Follicles on the upper tarsal conjunctivaLimbal follicles like Herbe pitsConjunctival scarring (Trichiasis, Entropion )Vascular pannus at superior limbus(Refer: AH Khurana, Comprehensive Textbook of Ophthalmology,5thedition, pg no: 62-66)", "cop": 2, "opa": "Follicles over the cornea", "opb": "Follicles in palpebral conjunctiva", "opc": "Follicles in bulbar conjunctiva", "opd": "Papillae in bulbar conjunctiva", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "043672af-d75b-4025-a288-6ced72388109", "choice_type": "single"} {"question": "The only cranial nerve to emerge from dorsal aspect of brainstem is", "exp": ".Surface attachment. Trochlear nerve is attached to the superior medullary velum one on each side of the frenulum veil just below the inferior colliculus. It is the only cranial nerve which emerges on the dorsal aspect of the brainstem. Ref : B D Chaurasia's Human Anatomy, sixth edition, volume 3 , pg. no. 364 Ref : B D Chaurasia's Human Anatomy, sixth edition, volume 3 , pg. no. 364 ( fig . 24. 1 )", "cop": 2, "opa": "3rd nerve", "opb": "4th nerve", "opc": "5th nerve", "opd": "6th nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9ab21739-bae6-4d7f-83c0-d9d4823ccf17", "choice_type": "single"} {"question": "Auditory transmission is via", "exp": null, "cop": 1, "opa": "Lateral lemniscus", "opb": "Medial lemniscus", "opc": "Lateral geniculate body", "opd": "Frontal cortex", "subject_name": "Anatomy", "topic_name": null, "id": "b5785c53-83b7-43e6-9173-ee1562c84ab6", "choice_type": "single"} {"question": "The lymphatic drainage of the glans penis is", "exp": "B i.e. Deep inguinal lymph nodes", "cop": 2, "opa": "Superficial inguinal lymph nodes", "opb": "Deep inguinal lymph nodes", "opc": "Para-aoic lymph nodes", "opd": "internal iliac lymph nodes", "subject_name": "Anatomy", "topic_name": null, "id": "7ec53ec3-59e5-4ff6-aae5-330d6bc46734", "choice_type": "single"} {"question": "Middle superior alveolar nerve is branch of", "exp": "MAXILLARY NERVE DIVISION: IN MIDDLE CRANIAL FOSSA-Meningeal branch IN PTERYGOPALATINE FOSSA-Ganglionic branches Zygomatic: a.Zygomaticotemporal b.Zygomaticofacial Posterior superior alveolar IN INFRAORBITAL CANAL-Middle superior alveolar Anterior superior alveolar ON FACE-Infraorbital:palpebral,labial,nasal Ref BDC volume 3,sixth edition pg 368", "cop": 2, "opa": "Mandibular nerve", "opb": "Maxillary nerve", "opc": "Lingual nerve", "opd": "Facial nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "2d02d8a6-01a3-4846-8c15-93103894cbb6", "choice_type": "single"} {"question": "Eruption of 1st molar permanent tooth occurs at the age of", "exp": "Eruption of permanent molar teeth: First molar( upper jaw) - 6-7 yrs First molar ( lower jaw) -. 6-7 yrs Second molar (upper jaw)- 12-13yrs Second molar(lower jaw)-11-13yrs Third molar(upper jaw)-17-21yrs Third molar(lower jaw)-. 17-21yrs Hence, the eruption of first molar permanent tooth is at the age of 6-7 yrs. Ref: Ghai, 9th edition- Pg-11.", "cop": 2, "opa": "4-5 yrs", "opb": "6-7 yrs", "opc": "7-8 yrs", "opd": "8-10 yrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d67d8ce1-bbf8-4595-8a1d-5c7a229ae03e", "choice_type": "single"} {"question": "Not present in sideroblastic anemia is", "exp": "Ref Harrison 19 th ed pg 628 when the marrow smear is stained for iron, 20-40% of developing erythroblasts--called sideroblasts--will have visible ferritin granules in their cytoplasm. This represents iron in excess of that needed for hemoglobin synthesis. In states in which release of iron from storage sites is blocked, RE iron will be detectable, and there will be few or no sideroblasts.", "cop": 2, "opa": "Microcytic anemia", "opb": "Decreased transferrin saturation", "opc": "Sideroblastic cells in blood smear", "opd": "Ineffective erythropoiesis", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "6e00e74e-5d4a-44de-b31a-6ba312d73963", "choice_type": "single"} {"question": "A congeital hydrocele is treated by", "exp": "Congenital hydrocele will resolve spontaneously within 1 year. The operation is required only when it persists for longer than 1 year\" In congenital hydrocele, the processes vaginalis is patent and connects with the peritoneal cavity. The communication is usually too small to allow herniation of intra-abdominal contents. Pressure on the hydrocele does not always empty it but the hydrocele fluid may drain into the peritoneal cavity when the child is lying down; thus, the hydrocele is often intermittent. Ascites should be considered if the swellings are bilateral. \"Congenital hydroceles are treated by herniotomy if they do not resolve spontaneously\" Treatment usually, no treatment of congenital hydrocele is indicated because this condition typically resolves spontaneously by age 1. Most surgeons advocate observation in the majority of infants less than 12 months. Others may continue to be observed for longer, as the majority of patent processes vaginalis will close within the first 12-24 months of life", "cop": 3, "opa": "No t/t before 5 years", "opb": "Herniorraphy", "opc": "Herniotomy", "opd": "Eversion of sac", "subject_name": "Anatomy", "topic_name": "Urology", "id": "dfb10b88-41c4-4e69-8bb5-7f9b504a8aad", "choice_type": "single"} {"question": "Abducens supplies", "exp": "*Abducent is the 6th cranial nerve *All the extraocular muscles are supplied by 3rd cranial nerve except lateral rectus and superior oblique *Lateral rectus by abducent nerve and superior oblique by trochlear nerve NOTE:MNEMONICS:LR6 & SO4 Ref: BDC 6th edition pg:208(3rd vol)", "cop": 2, "opa": "Medical rectus", "opb": "Lateral rectus", "opc": "Inferior oblique", "opd": "Superior oblique", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d04a474a-5fd4-4e50-99a1-388638f27baf", "choice_type": "single"} {"question": "Type of connective tissue present in the arrow marked area is", "exp": "The arrow mark shows the deep reticular layer of dermis, which is made up of dense and irregular connective tissue. Location Dense irregular: Capsule of visceral organs Periosteum, perichondrium Sheaths of nerves, muscles etc Dense regular Tendons, aponeurosis, ligament Deep fascial", "cop": 3, "opa": "Loose areolar", "opb": "Loose reticular", "opc": "Dense irregular", "opd": "Dense regular", "subject_name": "Anatomy", "topic_name": "Glands & Connective tissue", "id": "cbd92101-8e27-4fbb-8542-94bbc2e2fb08", "choice_type": "single"} {"question": "Freezing point of normal human plasma is", "exp": "The freezing point of normal human plasma averages _0.54degC which corresponds to osmolar concentration in plasma of 290 mOsm/L The term tonicity is used to describe the osmolality of a solution relative to plasma A 0.9% saline solution and 4% glucose solution is isotonic when initially infused intravenously osmolarity= 2(Na+)(mEq/L)+0.055(glucose)(mg/dL)+0.36(BUN)(mg/dL) Red Robbins 9/e p420 and ananthanaraya", "cop": 3, "opa": "4degC", "opb": "0degC", "opc": "_0.54degC", "opd": "_1.54degC", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "1ae0f9d7-5ebe-4e19-830b-6be193d139a5", "choice_type": "single"} {"question": "A most common tumour of urinary bladder is", "exp": "3 histological types of Bladder cancer are seen transitional cell ca -90% squamous cell ca -5~10% adenocarcinoma - 2%", "cop": 4, "opa": "Squamous cell carcinoma", "opb": "Adenocarcinoma", "opc": "Stratified squamous carcinoma", "opd": "Transitional carcinoma", "subject_name": "Anatomy", "topic_name": "Urology", "id": "e72e93eb-2087-4240-9ae4-1fdec6788ced", "choice_type": "single"} {"question": "D_Dimer is the most sensitive diagnosis test for", "exp": "Ref Robbins 9/e p127 D-Dimer ia a fibrin degradation product ,a small protein fragment present in blood after a blood clot is degraded by fibrinolysis,it is so named because it contains 2crosselinkedDFragments of fibrinogen protein", "cop": 1, "opa": "Pulmonary embolism", "opb": "Acute pulmonary oedema", "opc": "Cardiac tamponade", "opd": "Acute myocardial infraction", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "af97326a-1689-448c-9c6f-495c29c5c96b", "choice_type": "single"} {"question": "One of the following is a midline neck swelling", "exp": "Midline swelling of the neck from above downwards Ludwigs angina Enlarged submental lymph nodes Sublingual dermoid Lipoma in the submental region Thyroglossal cyst Subhyoid bursitis Goitre Lipoma & enlarged lymph nodes in the suprasternal space of burns Retrosternal goitre Thymic swelling (A dermoid cyst may occur anywhere in the midline) Ref : Bailey & Love 25/e p729", "cop": 2, "opa": "Carotid body tumor", "opb": "Thyroglossal cyst", "opc": "Branchial cyst", "opd": "Cystic hygroma", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "7302068c-f5af-4d61-a73b-d9683c6eb3bb", "choice_type": "single"} {"question": "Orchiectomy is not indicated in", "exp": "For tubercular epididymitis, usually ATT is sufficient, if resolution does not occur, then epididymectomy can be done. (Orchiectomy is done if pt. has orchitis, non-responsive to ATT).", "cop": 3, "opa": "Seminoma testis", "opb": "Prostatic carcinoma", "opc": "tubercular epididymitis", "opd": "Male breast cancer", "subject_name": "Anatomy", "topic_name": "Urology", "id": "22fcf2a7-d2ee-4e89-9ff9-a61f0d76b7dd", "choice_type": "single"} {"question": "Filum terminate extend up to", "exp": "(C) Coccyx # Level of Spinal Cord:> Spinal cord extends from C1 to L1 (lower border) in adults> Spinal cord extends from C1 to L3 (upper border) in infants.> Filum terminate extends from lower end of spinal cord (L1 or L3) to the tip of coccyx.> Piamater extends up to tip coccyx> Dural sheath extends up to S2 vertebra.> Subdural space extends up to S2> Subarachnoid space extends up to S2", "cop": 3, "opa": "S5", "opb": "L5", "opc": "Coccyx", "opd": "L4", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "113baa7d-f0df-444b-9bf1-57ad4ddf45b4", "choice_type": "single"} {"question": "The main Side effect of Imatinib mesylate", "exp": "The main side effects are fluid retention, nausea, muscle cramps, diarrhea, and skin rashes.", "cop": 2, "opa": "Leg ulcers", "opb": "Fluid retention", "opc": "Flagellate hyperpigmentation", "opd": "Irreversible myelosuppression", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "09d78b74-30c4-4f7b-861b-a1398e29fd2b", "choice_type": "single"} {"question": "Internal opening of brachial fistula is located at", "exp": null, "cop": 4, "opa": "Around 3rd molar", "opb": "Around 2nd Premolar", "opc": "Behind Palatoglossal Arch", "opd": "Fossa of Tonsils", "subject_name": "Anatomy", "topic_name": null, "id": "7ff1a40f-1514-4fe2-b1bb-b9a53353cc71", "choice_type": "single"} {"question": "A “Potential Anastomosis” seen in", "exp": "Arterial anastomosis is the communication between the arteries, or branches of arteries. It may be actual or potential.\n\nActual Arterial Anastomosis: In actual arterial anastomosis the arteries meet end to end. For example, palmar arches, plantar arch, circle of Willis, intestinal arcades, labial branches of facial arteries.\nPotential Arterial Anastomosis: In potential arterial anastomosis the communication takes place between the terminal arterioles. Such communications can dilate only gradually for collateral circulation. Therefore on sudden occlusion of a main artery, the anastomosis may fail to compensate the loss. The examples are seen in the coronary arteries and the cortical branches of cerebral arteries.", "cop": 3, "opa": "Labial branch of facial artery", "opb": "Intercostal artery", "opc": "Coronary artery", "opd": "Arterial arcades of mesentery", "subject_name": "Anatomy", "topic_name": null, "id": "a1fc86c3-46f3-4f7b-a6ff-33e9aa974654", "choice_type": "single"} {"question": "Kviem siltzbach test is is used in diagnosis of", "exp": "The Kviem-Siltzbach procedure is a specificdiagnostic test for sarcoidosis. An intradermalinjection of specially prepared tissue derived from the spleen of a known sarcoidosis patient is biopsied 4-6 weeks after injection. Ref Harrison 19th edition pg 2210", "cop": 2, "opa": "Tuberculosis", "opb": "Sarcoidosis", "opc": "Histoplasmosis", "opd": "Leishmaniasis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "404ffd64-6408-438f-ba2e-67376e1304f6", "choice_type": "single"} {"question": "Posterior communicating aery connects", "exp": "Posterior communicating aery connects the internal carotid aery with posterior cerebral aery.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 172)", "cop": 3, "opa": "Two posterior cerebral aeries", "opb": "Posterior cerebral aery with middle cerebral aery", "opc": "Posterior cerebral aery with internal carotid aery", "opd": "Anterior cerebral aery with middle cerebral aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "9cb4260d-fa2a-47a0-a6de-32b549156764", "choice_type": "single"} {"question": "Vanishing bile duct syndrome is seen in", "exp": "Vanishing bile duct syndrome Rare condition characterised by decreased number of bile ducts seen in liver biopsy specimens Causes Chronic rejection after liver transplantation Graft versus host disease after BMI transplantation Sarcoidosis Drugs: Chlorpromazine Idiopathic Ref : Harrison's 19th edition Pgno : 2027-2028", "cop": 2, "opa": "Chronic viral hepatitis", "opb": "Sarcoidosis", "opc": "Lymphoma", "opd": "Non - cirrhotic poal fibrosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "42810159-62b5-4d11-8f81-5cf3b0263737", "choice_type": "single"} {"question": "Rotator interval is between", "exp": "Refer Essentials of Ohopedic surgery Rotator interval is a triangular poion of shoulder capsule which lies between supraspinatus and subsacapularis tendon", "cop": 3, "opa": "Supraspinatus and trees minor", "opb": "Teres major and teres minor", "opc": "Supraspinatus and subsacapularis", "opd": "Subsapalris and infraspinatus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e7712da9-f9d4-4c8d-b6cd-c2b6913e2df2", "choice_type": "single"} {"question": "Lewis triple response is caused due to", "exp": "Ref Goodman and Gilman 10/e p650 With injection of histamine there is triple response Red spot Wheal Flare", "cop": 1, "opa": "Histamine", "opb": "Axon reflex", "opc": "Injury to endothelium", "opd": "Increased permeability", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5d03624a-73c3-44ba-abe9-52789edfa93a", "choice_type": "single"} {"question": "Nerve of inguinal canal is", "exp": "The inguinal canal is a passage in the anterior abdominal wall that in men conveys the spermatic cord and in women the round ligament of uterus. The inguinal canal is larger and more prominent in men. There is one inguinal canal on each side of the midline. ref -BDC 6e vol2 pg211-216", "cop": 4, "opa": "Genitofemoral nerve", "opb": "Obturator nerve", "opc": "Iliohypogastric nerve", "opd": "Ilioinguinal nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "73084877-91f0-4263-86c1-2261719dbb3b", "choice_type": "single"} {"question": "A derivative of neural Crest is", "exp": "Neural Crest Cells During elevation of the neural plate, a group of cells appears along each edge (the crest) of the neural folds (Fig. 18.2). These neural crest cells are ectodermal in origin and extend throughout the length of the neural tube. In addition to forming sensory ganglia, cells of the neural crest differentiate into sympathetic neuroblasts, Schwann cells, pigment cells, odontoblasts, meninges, and mesenchyme of the pharyngeal arches. Ref: Langman's embryology; Pg 306 Mnemonic:SOME GAP S-Schwann cells -Skeleton of face O-odontoblasts M-Meninges(pia and arachnoid) E-Endocardial cushion G-Ganglia(autonomic and dorsal root ganglia) A-Adrenal medulla -Aoicopulmonary septum P-Pigmant cells(melanocytes) -Pharyngeal arches(nerves and cailage) -parafollicular c cells of thyroid", "cop": 3, "opa": "Para follicular cells of thyroid", "opb": "Adrenal crest", "opc": "Schwann cells", "opd": "Dorsal roo ganglia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b231f093-1091-4be8-a62f-5ba4e05fcc4b", "choice_type": "single"} {"question": "Inferior Gluteal Nerve Supplies", "exp": "INFERIOR GLUTEAL NERVE :Root value: L5, SI, S2Course: Enters the gluteal region through greater sciatic notch below piriformis muscle Branches: It gives a number of branches to gluteus maximus muscle only. It is the sole supplier to the large antigravity, postural muscle with red fibers, responsible for extending the hip joint.Reference: Chaurasia Volume II; 7th edition; Page no: 73", "cop": 1, "opa": "Gluteus Maximus", "opb": "Gluteus Medius", "opc": "Gluteus Minimus", "opd": "Tensor Fascia Lata", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "c973a21b-07ed-4333-9744-d38712c5f2ae", "choice_type": "single"} {"question": "Inferior thyroid artery arises from", "exp": null, "cop": 2, "opa": "1st part of subclavian artery", "opb": "Thyrocervical trunk of 1st part of subclavian artery", "opc": "3rd part of subclavian artery", "opd": "Internal carotid artery", "subject_name": "Anatomy", "topic_name": null, "id": "63890391-f0d2-4c0c-ae37-9703a2e64a36", "choice_type": "single"} {"question": "Hemiazygous vein crosses left to right at the level of", "exp": "Hemiazygos vein turns to the right at the level of T8 B D CHAURASIA&;S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION Page no-224", "cop": 1, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "T6", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "bd8c5f98-2b36-4aa3-81c4-e3cd6d1a99d2", "choice_type": "single"} {"question": "The vein in the cardiac anterior interventricular groove is", "exp": "The Great cardiac vein accompanies first the anterior interventricular aery and then the left coronary aery to enter the left end of the coronary sinus. B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 FIFTH EDITION Page no-254", "cop": 1, "opa": "Great Cardiac Vein", "opb": "Anterior cardiac vein", "opc": "Posterior cardiac vein", "opd": "Thebesian vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "880e5cf6-af3e-4513-ab57-d40a10c52921", "choice_type": "single"} {"question": "The pharmakokinetic change occurring in geriatric patient is due to", "exp": "One of the most impoant pharmacokinetic changes associated with aging is decreased renal elimination of drugs. After age 40, creatinine clearance decreases an average of 8 mL/min/1.73 m2/decade; however, the age-related decrease varies substantially from person to person. Serum creatinine levels often remain within normal limits despite a decrease in GFR because older adults generally have less muscle mass and are generally less physically active than younger adults and thus produce less creatinine. Maintenance of normal serum creatinine levels can mislead clinicians who assume those levels reflect normal kidney function. Decreases in tubular function with age parallel those in glomerular function. Refer katzung 11/e p1039", "cop": 3, "opa": "Gastric absorption", "opb": "Liver metabolism", "opc": "Renal clearance", "opd": "Hypersensitivity", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4e6de6fe-8c69-4553-827d-417ce597f3ac", "choice_type": "single"} {"question": "Aicularis genu is related to", "exp": "Vastus intermedius- arises from the upper three-fouhs of the anterior and lateral surface of shaft of femur. Aicularis genu arises just below the vastus intermedius. Vastus lateralis-arises from upper pa of interochanteric line, anterior and inferior aspects of the greater trochanter, the lateral margin of the gluteal tuberosity, and the upper half of the lateral lip of linea aspera. Vastus medialis: lower pa of interochanteric line, the spiral line, medial lip of linea aspera, and the medial supracondylar line. Rectus femoris: Straight head- anterior inferior iliac spine.Reflected head-margin of acetabulum and capsule of hip joint. {Reference: BDC 6E pg no.16,17}", "cop": 2, "opa": "Vastus lateralis", "opb": "Vastus intermedius", "opc": "Vastus medialis", "opd": "Rectus femoris", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "faa7f906-f005-4d47-a036-acc0565e025a", "choice_type": "single"} {"question": "Lattice degeneration seen in", "exp": "Peripheral retinal degenerations common in pathological myopia", "cop": 4, "opa": "Hypermetropia", "opb": "Anisocoria", "opc": "Glaucoma", "opd": "Myopia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "108ab972-75d1-4589-8f2d-b70a08ad051b", "choice_type": "single"} {"question": "The cerebrospinal fluid", "exp": "The cerebrospinal fluid is a modified tissue fluid. It is contained in the ventricular system of the brain and in the subarachnoid space around the brain and spinal cord. The bulk of cerebrospinal fluid is formed by the choroid plexuses of the lateral ventricles and lesser amounts by the choroid plexuses of third and fouh ventricles Ref BDC volume3,6th edition pg 331", "cop": 2, "opa": "10% of it drain to cerebral lymphatics", "opb": "Formed by choroid plexus mostly", "opc": "Mostly found in skull bones than in spine", "opd": "Through aqueduct passes from lateral ventricle to 3rd ventricle", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "c8f141d8-f361-4da8-897f-bf01d1615d5f", "choice_type": "single"} {"question": "Sperm maturation takes place in", "exp": "Sperm maturation takes place in epididymis. The seminiferous tubules of the testis are the staing point of the process, where spermatogonial stem cells adjacent to the inner tubule wall divide in a centripetal direction- beginning at the walls and proceeding into the innermost pa or lumen to produce immature sperm. Ref - BDC 6e vol2 pg226", "cop": 3, "opa": "Vas deferens", "opb": "Seminiferous tubules", "opc": "Epididymis", "opd": "Female genital tract", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c34305e2-252f-4e20-94fb-7cd9fe80c26f", "choice_type": "single"} {"question": "Left common cardinal vein is reduced to", "exp": "Left common cardinal vein is reduced to coronary sinus Ref Human embryology Inderbir singh Tenth edition Page 232", "cop": 4, "opa": "Great cardiac vein", "opb": "Azygos vein", "opc": "SVC", "opd": "Coronary sinus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ec48bad8-6b9a-40da-a0c2-5d3bb003138a", "choice_type": "single"} {"question": "In a detached retina, the site of detachment is found", "exp": "The site of retinal detachment is between the pigment epithelial layer and the layer of outer segments of rods and cones; this corresponds to the intraretinal space between the inner and outer layers of the optic cup. Retinal detachment occurs when fluid from the vitreous compament passes through a retinal hole and separates the pigment epithelial layer from the layer of outer segments of rods and cones.", "cop": 4, "opa": "Within the outer plexiform layer", "opb": "Within the inner plexiform layer", "opc": "Between the inner nuclear layer and the outer nuclear layer", "opd": "Between the pigment epithelial layer and the layer of outer segments of rods and cones", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "e660eb1d-ce6d-47ad-b056-6ce124782f0a", "choice_type": "single"} {"question": "LMP 1 gene plays a role in oncogenesis induced by", "exp": "Ref Robbins 9/e p328 LMP 1 gene plays a role in oncogenesis induced by EBV Epstein-Barr virus latent membrane protein 1 (LMP1) is expressed in multiple human malignancies, including nasopharyngeal carcinoma and Hodgkin and immunosuppression-associated lymphomas. LMP1 mimics CD40 signaling to activate multiple growth and survival pathways, in paicular, NF-kB. LMP1 has critical roles in Epstein-Barr virus (EBV)-driven B-cell transformation, and its expression causes fatal lymphoproliferative disease in immunosuppressed mice. Here, we review recent developments in studies of LMP1 signaling, LMP1-induced host dependency factors, mouse models of LMP1 lymphomagenesis, and anti-LMP1 immunotherapy approaches", "cop": 3, "opa": "Human T cell leukemia virus type 1", "opb": "Hepatitis B virus", "opc": "Epstein Barr virus", "opd": "Human papilloma virus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9abd5a2b-04c3-4a3e-9a66-16949c3d5f31", "choice_type": "single"} {"question": "Location of beta 3 receptors include", "exp": ".", "cop": 3, "opa": "Bronchial muscle", "opb": "Vascular muscle", "opc": "Bladder", "opd": "Uterus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f8455199-b504-4b65-8748-a1584e26868b", "choice_type": "single"} {"question": "Typical JVP finding in cardiac tamponade", "exp": "Ref Harrison 19 th ed pg 1462 Cardiac tamponade is characterized by jugular venous diatenaiod ( increased JVP) with a prominent X descent but an ,absent Y descent.", "cop": 1, "opa": "Absent 'Y' descent", "opb": "Prominant 'a' wave", "opc": "Absent 'a' wave", "opd": "Prominant 'Y' wave", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "74338f95-23a2-437f-ad8a-522728e7dd9c", "choice_type": "single"} {"question": "Muscle attached to anterior surface of greater trochanter", "exp": "Gluteus minimus is most anterior in attachment & Gluteus Maximus is most posterior. Muscle Inseion Gluteus maximus Gluteal tuberosity (1/4), iliotibial tract (3/4) Gluteus Medius Greater trochanter of femur (Lateral surface) Gluteus minimus Greater trochanter of femur (anterior surface) Piriformis Apex of greater trochanter of femur", "cop": 3, "opa": "Gluteus Maximus", "opb": "Gluteus Medius", "opc": "Gluteus Minimus", "opd": "Piriformis", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "ea229adb-42b0-4a01-8e30-b142c1ff972d", "choice_type": "single"} {"question": "A carbuncle is best treated by", "exp": "Treatment - Carbuncle Proper excision by cruciate incision will usually treat the condition effectively Surgical incision and drainage of all Suppurative collections with antibiotics Ref: www.ncbi.nlm.nih.gov", "cop": 2, "opa": "Antibiotics alone", "opb": "Incision and drainage", "opc": "Conservative management", "opd": "Cruciate incision and deroofing", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d89e6bbf-c40f-4500-baa8-366811e646d3", "choice_type": "single"} {"question": "Hyperoxygenation of premature infants may result in", "exp": "Retrolental fibroplasia results from hyperoxygenation of premature infants. In premature infants, high oxygen concentration results in obliteration of the terminal aerioles, leading to hemorrhage and infarction of the retina. This phenomenon is peculiar to the incompletely vascularized peripheral retina.", "cop": 4, "opa": "Congenital glaucoma", "opb": "Microphthalmia", "opc": "Coloboma", "opd": "Retrolental fibroplasia", "subject_name": "Anatomy", "topic_name": "Eye, Nose and Ear", "id": "7b70bbe0-2d40-46b0-99ea-9cd77c3bc829", "choice_type": "single"} {"question": "Ureter develops from", "exp": null, "cop": 4, "opa": "Pronephros", "opb": "Metanephros", "opc": "Mesonephros", "opd": "Mesonephric duct", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "ad096e80-d779-48c0-b865-2617e186dda3", "choice_type": "single"} {"question": "Embryonic period is upto", "exp": "Embryo refers to the product of conception from the day of feilization to 8 weeks Prenatal period Ovum- 0-2 wks Embryo- 3-8wks Foetus- 9wks - bih Postnatal period Newborn- first 4wks after bih Infant- Bih to 12months Toddler- 1yr to 36 months Preschool child- 37 to 72 months School age child- 73 months to 12yrs Adolescence Early- 10-13 yrs Middle- 14-16 yrs Late- 17-20yrs Ref: Ghai, 9th edition, Chapter 2, Table 2.1", "cop": 1, "opa": "8 weeks", "opb": "10 weeks", "opc": "12 weeks", "opd": "6 weeks", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cef0213d-921f-44f5-9e23-37deae03c986", "choice_type": "single"} {"question": "Zero order kinetics occur in following drug with high dose", "exp": "Phenytoin and thiophylline follows zero order kinetics with high dose as it follow linear with time Ref -KDT 6/e p31,138", "cop": 1, "opa": "Phenytoin and theophylline", "opb": "Digoxin and prapranol", "opc": "Amiloride and probenecid", "opd": "Lithum and thiophylline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e9454a66-348c-49eb-a778-11a88786bd20", "choice_type": "single"} {"question": "Fascia around nerve bundle of brachial plexus is derived from", "exp": "The muscular floor of the posterior triangle is covered by preveebral layer of deep cervical fascia which forms the fascial carpet of the floor of posterior triangle.The axillary sheath around subclan aery and brachial plexustravelling from root of neck to the upper limb.pus collected in the posterior triangle deep to its fascial carpet from tubercular cervical veebrae may track downwards and laterally along the axillary sheath to first appear in the axilla or even in the arm subsequently.Reference: Textbook of anatomy, Upper limb, and thorax, Vishram Singh, 2nd edition, page no.80", "cop": 1, "opa": "Preveebral fascia", "opb": "Pretracheal fascia", "opc": "Investing layer", "opd": "Superficial cervical fascia", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a28a7eac-9186-4748-923a-6bc729b52fb7", "choice_type": "single"} {"question": "Verocay bodies are seen in", "exp": "Schwannoma are well circumscribed encapsulated masses that abut the associated nerve without invading it", "cop": 4, "opa": "Memingioma", "opb": "Hemangioma", "opc": "Glioma", "opd": "Shwannoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fa486197-aa01-4961-9b8b-7db900d6170d", "choice_type": "single"} {"question": "Posterior superior iliac spine is at the level of", "exp": "PSIS line identifies the S2 spinous process most frequently", "cop": 3, "opa": "L5", "opb": "S1", "opc": "S2", "opd": "S3", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8f554a65-7ec7-449b-a2ca-865e2edf2a95", "choice_type": "single"} {"question": "drug with teratogenic potential is", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential ref. kaplon and sadock, synopsis of psychiatry, 11 th edition,pg no.935", "cop": 1, "opa": "carbamezepine", "opb": "clonazepam", "opc": "risperidone", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "6bfe94ee-1568-4ea6-bd6e-9f55bd073bef", "choice_type": "single"} {"question": "The diameter of Tricuspid orifice is", "exp": "ValveDiameter of OrificePulmonary2.5cmAoic2.5cmMitral3cmTricuspid4cmRef: BD Chaurasia; Volume 1; 6th edition; Table 18.1", "cop": 4, "opa": "2cm", "opb": "2.5cm", "opc": "3cm", "opd": "4cm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "2907ab39-83ce-40d9-8be0-fbea58bfffe0", "choice_type": "single"} {"question": "A 12 year old boy presents with hemetemesis, melena and mild splenomegaly. There is no obvious jaundice or ascites. The most likely diagnosis is", "exp": "Extrahepatic poal venous obstruction (EHPVO) EHPVO is a vascular disorder of the liver Obstruction of the extrahepatic poal vein with or without involvement of the intrahepatic poal veins or splenic or SMV Most common site of obstruction is at the confluence of splenic vein and SMV EHPVO is the most common cause of upper Gastrointestinal bleeding in children Accounts for almost 70: of pediatric patients with poal hypeension Clinical features It can present in two forms Recent EPHVO : Abdominal pain, ascites or fever, may be asymptomatic Chronic EPHVO : Repeated, well tolerated bleeding episodes from esophageal varices Ectopic varices are common (duodenum, anorectal region, biliary tree and gallbladder) manifest as obscure GI bleed, bleeding per rectum or biliary obstruction Moderate splenomegaly is universal and may be a presenting feature A propoion of children have growth retardation Ref: Blumga 5th edition Pgno : 1099-1105", "cop": 1, "opa": "EHPVO", "opb": "NCPF", "opc": "Cirrhosis", "opd": "Malaria with DIC", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ff500c57-e7fc-41f9-a453-5bd1cf92dde2", "choice_type": "single"} {"question": "Most common tumor of appendix is", "exp": "Refer Robbins page no 9/e 816 Cancer of the appendix may causeappendicitis or rupture of appendicitis. Mostly this is the first symptom of appendix cancer. The majority of appendiceal tumors arecarcinoids, while the remaining 10% to 20% are mucinous cyst-adenocarcinoma,adenocarcinoma, lymphosarcoma,paraganglioma, and granular-cell tumors.", "cop": 1, "opa": "Carcinoid tumor", "opb": "Pseudomyxoma peritonitis", "opc": "Adenocarcinoma", "opd": "Mucocele", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3769dea6-b263-4edb-bf48-42ad57704a05", "choice_type": "single"} {"question": "Sho gastric aeries are branches of", "exp": "The left gastric aery arises from the celiac aery. It supplies the lower third of the esophagus and the upper right pa of the stomach.The right gastric aery arises from the hepatic aery at the upper border of the pylorus and runs to the left along the lesser curvature. It supplies the lower right pa of the stomach.The sho gastric aeries arise from the splenic aery at the hilum of the spleen and pass forward in the gastrosplenic omentum (ligament) to supply the fundus.The left gastroepiploic aery arises from the splenic aery at the hilum of the spleen and passes forward in the gastrosplenic omentum (ligament) to supply the stomach along the upper pa of the greater curvature.", "cop": 2, "opa": "Celiac aery", "opb": "Splenic aery", "opc": "Left gastroepiploic aery", "opd": "Left gastroepiploic aery", "subject_name": "Anatomy", "topic_name": null, "id": "e98135ee-8c2d-4f65-9e17-71e58c8d6680", "choice_type": "single"} {"question": "In obstruction of second pa of axillary aery, the anastomosis between the following aery will maintain the blood supply of upper limb", "exp": "When the axillary aery is blocked, collateral circulation is established through the anastomosis around scapula which links the first pa of the subclan aery with the third pa of axillary aery(apa from the communications with the posterior intercostal aeries). The transverse cervical aery is a branch of the subclan aery and the subscapular aery is a branch of the second pa of the axillary aery. BD Chaurasia 7th edition Page no: 55", "cop": 1, "opa": "Deep branch of transverse cervical aery & subscapular aery", "opb": "Anterior & posterior circumflex humeral", "opc": "Posterior circumflex humeral & circumflex scapular aery", "opd": "Suprascapular & anterior circumflex humeral aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "c6f4cb19-fcd1-43cb-86df-9fbc90986bae", "choice_type": "single"} {"question": "Posterior belly of digastric is supplied by", "exp": "Ans. is `a' i.e., Facial nerve", "cop": 1, "opa": "Facial nerve", "opb": "Mandibular nerve", "opc": "Glossopharyndeal nerve", "opd": "Trochlear nerve", "subject_name": "Anatomy", "topic_name": null, "id": "813fe692-05b6-4357-83c2-ca3537263fda", "choice_type": "single"} {"question": "Mesodermal in origin among the following is", "exp": "There is a third type of neuroglial cell called microglia. This type doesn't develop from the cells of the neural tube but migrates into it along with blood vessels. These cells are believed to be of mesodermal in origin HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:116", "cop": 4, "opa": "Astrocytes", "opb": "Oligodendrocytes", "opc": "Ependymal cells", "opd": "Microglial cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2ba859d7-4c3f-468b-b4fe-e60d32cb47ea", "choice_type": "single"} {"question": "In breast, Copper's ligament extends from subcutaneous tissue to", "exp": "B. i.e. Pectoral fascia Strands of fibrous tissue (forming the suspensory ligament of Cooper) connect the dermis of overlying skin to the ducts of breast (mammary gland) and pectoral fasciaQ. These suppo mammary gland lobule and help to maintain the protuberence of young breast. They also cause pitting of oedematons skin that results from malignant involvement of dermal lymphatics (peaud' orange) and dimpling of skin d/t fibrosis associated with ceain breast carcinomas.The fibrous stroma forms septa known as suspensory ligaments of cooper, which anchor the dermis of skin and gland to superficial pectoral fasciaQSuperficial pectoral fascia has two layers;- Superficial layer - Camper's fascia which contain mammary gland and?- Deep layer scarpa's fascia upto which Cooper's ligament extend", "cop": 2, "opa": "Pectoral muscle", "opb": "Pectoral fascia", "opc": "Alveoli", "opd": "Montgomery tubercle", "subject_name": "Anatomy", "topic_name": null, "id": "9c5ca7b8-c68f-48c3-94fb-f72e45ff2622", "choice_type": "single"} {"question": "Obstruction of IVC leads to", "exp": ".", "cop": 1, "opa": "Dilatation of thoracoepigastric veins", "opb": "Caput medusae", "opc": "Hemorrhoids", "opd": "Esophageal varices", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b61ca13b-df0b-4434-a9d9-1aab89ecd2aa", "choice_type": "single"} {"question": "Thoracic duct crosses at", "exp": "In the neck thoracic duct arches laterally at the level of C7 B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME-1 SIXTH EDITION Page no-285", "cop": 2, "opa": "T1", "opb": "C7", "opc": "T5", "opd": "T8", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d6742120-cf0f-45cc-81e5-1e8ce411e7fc", "choice_type": "single"} {"question": "The perilymph, present in the scala vestibule and scala tympani, drains into the CSF through the", "exp": "The perilymphatic chamber of the vestibular system has a wide connection to scala vestibuli, which in turn connects to scala tympani by an opening called the helicotrema at the apex of the cochlea. Scala tympani is then connected to the cerebrospinal fluid (CSF) of the subarachnoid space by the cochlear aqueduct. ref - BD chaurasia 6e vol3 pg", "cop": 1, "opa": "Aqueduct of cochlea", "opb": "Aqueduct of vestibule", "opc": "Ductus reunions", "opd": "Cochlear duct", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9f0251d9-f39a-47f2-a309-afa939bcbbb5", "choice_type": "single"} {"question": "The position of the hip in a patient with posterior dislocation of the hip is", "exp": "Position and attitude of hip pathology Flexion, Abduction, External rotationFlexion, Adduction, Internal rotationu1st stage of TB hip uAnterior dislocation of hip uFracture shaft of femur uPolio hipuHip joint effusion u2nd and 3rd stage of TB hip uPosterior dislocation of the hip uTraumatic hip dislocation (Refer: Watson Jones Textbook of Ohopedics & Trauma, 6thedition,pg no: 901-935)", "cop": 2, "opa": "Extension, abduction, internal rotation", "opb": "Flexion, adduction, internal rotation", "opc": "Flexion, abduction, internal rotation", "opd": "Flexion, abduction, external rotation", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c2a89232-599b-4f5f-bb64-a01357a28b1a", "choice_type": "single"} {"question": "Acute cholecystitis is caused by", "exp": "Causes of Acalculous cholecystitis Common causes Elderly and critically ill patients after trauma Burns Longterm TPN Major operations(Abdominal aneurysm repair and cardiopulmonary bypass) Diabetes mellitus Uncommon causes Vasculitis Obstructing GB adenocarcinoma GB torsion Parasitic infestation Unusual bacterial infection - Leptospira, streptococcus, salmonella , Vibrio cholera Ref: Harrison's 19th edition Pgno : 2081", "cop": 1, "opa": "Total parenteral nutrition", "opb": "Tuberculosis", "opc": "Anemia", "opd": "Malignancy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "63e2feb2-84d4-4acc-8a2f-c51aba249026", "choice_type": "single"} {"question": "In a female child at bih, oocyte is in a stage of", "exp": "Inderbir Singh&;s Human embryology; Tenth edition; Pg 24At the time of bih, all primary oocytes are in the prophase of the first meiotic division.", "cop": 2, "opa": "Anaphase of the first meiotic division", "opb": "Prophase of the first meiotic division", "opc": "Anaphase of the second meiotic division", "opd": "Prophase of the second meiotic division", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "28948476-a271-4ec2-8438-55b9981973f6", "choice_type": "single"} {"question": "Hofbauer cells are associated with", "exp": "Hofbauer cells are oval eosinophilic histiocytes with granules and vacuoles found in the placenta, which are of mesenchymal origin, in mesoderm of the chorionic villus, paicularly numerous in early pregnancy.", "cop": 3, "opa": "Single umbilical aery", "opb": "Maternal diabetes", "opc": "Early pregnancy", "opd": "Erythroblastosis foetalis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ccc5b6e4-70f5-4aef-a17e-9fed6ef07fd8", "choice_type": "single"} {"question": "NOT a content of Jugular Foramen", "exp": "(A) Hypoglossal nerve# JUGULAR FORAMEN may be subdivided into three compartments, each with their own contents.> Anterior compartment transmits the inferior petrosal sinus.> Intermediate transmits the glossopharyngeal, vagus, and accessory nerves ( cranial nerves number IX, X, and XI respectively).> Posterior transmits the sigmoid sinus (becoming the internal jugular vein) and some meningeal branches from the occipital and ascending pharyngeal arteries.", "cop": 1, "opa": "Hypoglossal nerve", "opb": "Glossopharyngeal nerve", "opc": "Occipital arteries", "opd": "Sigmoidal sinus", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "76a19948-8785-446d-9451-a281fa0490a5", "choice_type": "single"} {"question": "Superior intercostal aery is a branch of", "exp": "Superior intercostal arery is a branch of costocervical trunk of subclan aery. BD chaurasia's human anatomy.6th edition volume 1.page no 219.", "cop": 1, "opa": "Costocervical trunk", "opb": "Dorsal scapular aery", "opc": "Thyrocervical trunk", "opd": "Internal thoracic aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "06581457-c9f1-4a3f-aa65-91b9e748bc97", "choice_type": "single"} {"question": "Conversion of uroporphyrinogen III to coproporphyrinogen III is an example of", "exp": "(Refer Q 26)", "cop": 2, "opa": "Deamination", "opb": "Decarboxylation", "opc": "Hydrogenation", "opd": "Dehydrogenation", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "8861e1e4-de26-4e28-b759-fd09e19a4428", "choice_type": "single"} {"question": "Treatment in a patient suffering from Diffuse macular retinopathy is", "exp": ".", "cop": 3, "opa": "Macular ablation", "opb": "Pan retinal photocoagulation", "opc": "Grid pattern photocoagulation of macula", "opd": "Pan macular photocoagulation", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ec6c6eba-7f63-498e-aaa5-3a60e14a2da9", "choice_type": "single"} {"question": "The supinator muscle is supplied by", "exp": "SupinatorOrigin1.Lateral epicondyle of the humerus. 2.Radial collateral ligament of the elbow joint. 3.Annular ligament. 4.Supinator crest of the ulna, and the posterior pa of the triangular area in front of it.Inseion: Upper one-third of the lateral surface of the radius.Nerve Supply: Posterior interosseous nerve (C6, C7).Action: Supination of the forearm.Note: The muscles have two layers, superficial and deep. The posterior interosseous nerve runs downwards between these layers.Ref: BD Chaurasia; Volume 1; 6th edition; Page no: 133", "cop": 4, "opa": "Ulnar nerve", "opb": "Anterior interosseous nerve", "opc": "Median nerve", "opd": "Posterior interosseous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "818174c4-6b90-421b-b277-3ad4da8702c4", "choice_type": "single"} {"question": "Efficacy of the drug refers to", "exp": "Efficacy means effectiveness, i.e. the ability of something, e.g. a medicine, to produce the results you want Ref-KDT 7/e p54", "cop": 4, "opa": "Affinity of the drug to bind to the receptor", "opb": "Affinity of the drug that binds to the receptor and activates it", "opc": "Dose that required to to produce response", "opd": "Maximum response a drug can produce", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d146a142-a66d-464c-b59a-d84a85244785", "choice_type": "single"} {"question": "Procedure to be performed in the case of arrest of after coming head due to contracted pelvis in breech", "exp": "The last rescue for entrapped fetal head in term fetus is replacement of the fetus higher into the vagina and uterus followed by cesarean delivery this is zavanelli maneuver", "cop": 3, "opa": "Craniotomy", "opb": "Decapitation", "opc": "Zavanelli maneuver", "opd": "Cleidotomy", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "b11fa86b-c699-4625-98bf-36a31bc4a268", "choice_type": "single"} {"question": "Nerve not carrying taste sensation from tongue", "exp": "Trigmenial nerve does not carry taste sensation from tongue. Taste from tongue is medicated by chorda tympani nerve, a branch of facial nerve.", "cop": 1, "opa": "V", "opb": "VII", "opc": "IX", "opd": "X", "subject_name": "Anatomy", "topic_name": null, "id": "ae96fa5f-30fd-4b98-bab6-50c02fe75433", "choice_type": "single"} {"question": "Sclerosis of bony orbit is seen in", "exp": "Meningismus are tumor most common in women. Arising from the meningeal endothelial cells of the arachnoid villi. It is characterized by optiociliary shunts .if it involves the optic nerve sheath and in intracranial meningioma. It causes sclerosis of bony orbit Refer khurana 6/e p 423", "cop": 3, "opa": "Neurofibroma", "opb": "Retinoblastoma", "opc": "Meningioma", "opd": "Glioma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9548f690-7b50-4a57-b54c-651655c98cda", "choice_type": "single"} {"question": "Most common testicular tumour", "exp": "Seminoma is the most common germ cell tumor of the testis or, more rarely, the mediastinum or other extra- gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages.", "cop": 1, "opa": "Seminoma", "opb": "Teratoma", "opc": "Seoli cell tumour", "opd": "Chorio ca", "subject_name": "Anatomy", "topic_name": "Urology", "id": "f9ee5718-6ce5-4028-a9c2-1d4e61029d6e", "choice_type": "single"} {"question": "Primary action of superior oblique is", "exp": "actions of superior oblique: veical axis: depresses main action horizontal axis: abducts anteroposterior axis:rotates medically( intorsion) Ref.BDC volume 3:sixth edition pg 211", "cop": 1, "opa": "Intorsion", "opb": "Depression", "opc": "Adduction", "opd": "Abduction", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "4c3aa62b-d93c-4f05-8a8b-557ee6128b27", "choice_type": "single"} {"question": "Cutaneous supply over parotid gland is by", "exp": "3 main salivary glands include parotid gland, submandibular gland and sublingual gland. The skin over the parotid gland is supplied by the greater auricular nerve and auriculotemporal nerve. Greater auricular nerve supplies the greater pa of auricle& the auriculotemporal nerve supplies the anterior pa of auricle and temporal area, also carries secretomotor fibers to the parotid gland and sensory innervation of parotid gland Preganglionic parasympathetic fibers to the oticGanglion come from the glossopharyngeal nerve. Facial nerve (VII) exits the skull through stylomastoid foramen & then passes into parotid gland, where it usually divides into upper & lower trunk.", "cop": 2, "opa": "Auriculotemporal nerve", "opb": "Greater auricular nerve", "opc": "Greater occipital nerve", "opd": "Facial nerve", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "3129388c-0f5a-426e-8ab9-26779530b111", "choice_type": "single"} {"question": "After surgery, there was 50ml bile output from abdominal drain 1st preoperative day. Management is", "exp": "\"A small amount of biliary drainage following cholecystectomy should cause no alarm because it usually dissapears within 1 or 2 days. However, excessive bile drainage through the wound or drain site, jaundice, sepsis or a combination of these events early in post-operative period should suggest a bile-duct injury, as should copious biliary drainage for more than few post-op days Ref: Blumga 5th edition Pg no : 524-525", "cop": 4, "opa": "Intra biliary stent", "opb": "Immediate exploration", "opc": "T-tube drainage", "opd": "Observation", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7ca26fea-9764-4e9d-aed9-7a9bbf57d631", "choice_type": "single"} {"question": "Nerve of anterior compament of leg", "exp": "ANTERIOR COMPAMENT( leg):- Muscles:-1. Tibialis anterior 2. Extensor hallucis longus3. Extensor digitorum longus 4. Peroneus teius. Aery:anterior tibial aery.The blood supply of anterior compament is reinforced by the perforating branch of peroneal aery. Nerve:-Deep peroneal nerve. Arrangement:-From medial to lateral-Tibialis anterior EHLAnterior tibial aery and deep peroneal nerve EDL Peroneus teius DEEP PERONEAL:-Muscular branches to muscles of anterior compament of leg:Tibialis anterior, extensor hallucis longus,extensor digitorum longus and peroneus teius.Extensor digitorum brevis Cutaneous:dorsal digital nerves for adjacent sides of big toe and second toe.Aicular branches:Ankle joint, tarsal joints,tarsometatarsal joints and metatarsophalangeal joint of big toe. {Reference: BDC 6E pg no.93 diagram 8.4}", "cop": 2, "opa": "Superficial peroneal", "opb": "Deep peroneal", "opc": "Saphenous", "opd": "Sural", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "0d0d921a-cdb5-4d21-a0c8-5911356a806a", "choice_type": "single"} {"question": "Loss of alignment and over riding of bones of cranial vault seen in", "exp": "spadling sign Loss of alignment and over riding of the bones of cranial vault occurs due to shrinkage of the brain after death. This is known as spadling's sign. It may be detected within a few days of death of fetus in utero. Ref: TEXTBOOK OF FORENSIC MEDICINE AND TOXICOLOGY KRISHNAN VIJ FIFTH EDITION PAGE NO 148", "cop": 2, "opa": "Maceration", "opb": "Spadling's sign", "opc": "Mummification", "opd": "Plocquet's test", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "e80d747d-ebe5-4635-a50d-e3d30d7ebc91", "choice_type": "single"} {"question": "Hereditary chronic pancreatitis is caused by mutation of", "exp": "Hereditary pancreatitis Autosomal dominant disease Due to a missence mutation on cationic trypsinogen, or PRSS1(Protease, serine 1) results in premature, intrapancreatic activation of trypsinogen The incidence is equal in both sexes Ref: Sabiston 20th edition Pgno :1532", "cop": 1, "opa": "Cationic trypsinogen or PRSS1", "opb": "CFTR", "opc": "PTSI", "opd": "SPINK1", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b8c6e2be-ce35-4ab4-9581-5953099ffd15", "choice_type": "single"} {"question": "Pharmacodynamics includes", "exp": "Pharmacodynamics- the branch of pharmacology concerned with the effects of drugs and the mechanism of their action. Ref-KDT 7/e p1", "cop": 4, "opa": "Drug Elimination", "opb": "Drug excretion", "opc": "Drug Absorption", "opd": "Mechanism of action", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "12f45a95-8083-4d9a-9029-de7d4bf1848c", "choice_type": "single"} {"question": "Nucleus pulposus is a remnant of", "exp": "Inderbir Singh&;sHuman embryologyTenth edition Pg 60 As the embryo enlarges the notochord elongates considerably and lies in the midline in the position to be later occupied by veebral columnHowever, notochord does not give rise to veebral columnMost of it disappears but pas of it persist in the region of each interveebral disc as nucleus pulposus", "cop": 1, "opa": "Notochord", "opb": "Interveebral disc", "opc": "Spinal cord", "opd": "Spinous process", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d53da4c6-0910-45e7-b4a2-dcb2f5cbc3d9", "choice_type": "single"} {"question": "Ligament of Treitz", "exp": "1.It is a fibromuscular band to suppo the duodenojejunal flexure and arises from the right crus of the diaphragm.2.It has both the skeletal (diaphragmatic) as well as smooth (intestinal) muscles in it.3.It increases the DJ angulation and may cause paial obstruction at the site.It is also known as Suspensory ligament of the duodenum", "cop": 1, "opa": "Suppos DJ Flexure", "opb": "Is at Ileocaecal junction", "opc": "Arises from left crus of diaphragm", "opd": "Contain smooth muscle fibres only", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9e647eab-c507-44aa-8f44-f4af31d7a88b", "choice_type": "single"} {"question": "Triangle of ausculatation is seen in", "exp": "Triangle of auscultation is seen in 6 the intercoastal space B D CHOURASIAS HUMAN ANATOMY UPPER LIMB THORAX VOLUME, 1 SIXTH EDITION, PAGE NO, 64", "cop": 2, "opa": "5th intercostal space", "opb": "6th intercostal space", "opc": "7th intercostal space", "opd": "8th intercostal space", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d5ce3b49-093a-4234-a1bf-fee9f165dc0f", "choice_type": "single"} {"question": "The most common complication in spinal anaesthesia is", "exp": "During surgery 1. Hypotension most common complication Rx. Prophylactic preloading with 1-1.5L of fluids (colloid preferred) Curative: a Foot end elevation b Infusion of fluids (colloids better than crystalloids) c Vasopressors Mephentermine Ephedrine Phenyl Ephrine Dopamine (if not controlled) 2. Bradycardia Rx-Atropine 3. High Spinal complications depends on levels of block up to cardio-accelrator fibres then bradycardia & hypotension, if involves cervical Diaphragmatic paralysis occur Rx. IPPV 4. Resp. paralysis (Apnea) 5. Nausea & Vomiting Rx- oxygenation Correct hypotension Metoclopramide/ Ondansetron (if not C/I) 6. Apprehension & anxiety Rx-sedate the patient Post op. 1. urinary retention 2. Neurological complications A. Post spinal headache B. Cauda equina syndrome C. Paraplegia (mostly because of epidural haematoma) Rs: Exploration & drainage of haematoma D. Paralysis of cranial N. 6th most commonly (1st ,9th, 10th are not involved) E. Anterior spinal A. syndrome F. Meningitis 3. Backache", "cop": 2, "opa": "Post spinal headache", "opb": "Hypotension", "opc": "Meningitis", "opd": "Arrhythmia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "6d0a9143-d5a5-49c7-a480-d44927164f6f", "choice_type": "single"} {"question": "Anticholinesterases are ineffective against", "exp": "Refer katzung 11/e p 106,107 Anticholinergic drugs block the action of a neurotransmitter called acetylcholine. This inhibits nerve impulses responsible for involuntary muscle movements and various bodily functions. These drugs can treat a variety of conditions, from overactive bladder to chronic obstructive pulmonary disorder. These are ineffective against carbamate poisoning", "cop": 2, "opa": "Belladonna poisoning", "opb": "Carbamate poisoning", "opc": "Postoperative ileus", "opd": "Cobra bite", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ba3cab40-8468-4be5-a749-183ec6b80b08", "choice_type": "single"} {"question": "Diagnostic accuracy of a test is determined by its", "exp": "(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 149)", "cop": 3, "opa": "Sensitivity", "opb": "Specificity", "opc": "Predictive value", "opd": "Odds ratio", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "379e2054-89df-4de5-bec3-805a77568e13", "choice_type": "single"} {"question": "Green discharge is most commonly seen with", "exp": "A black or green discharge is usually the result of duct ectasia and its complications. Ref: Bailey and love 27th edition Pg no : 864", "cop": 2, "opa": "Duct papilloma", "opb": "Duct ectasia", "opc": "Retention cyst", "opd": "Fibro adenosis", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "326e56f1-fa4b-4b23-a590-c2cb42b38504", "choice_type": "single"} {"question": "Brodie&;s abscess is the terminology for", "exp": "It is a long standing localized pyogenic abscess in the bone(long standing because of strong defence mechanism of the body.) It usually involves long bones. Brodie&;s abscess - A circumscribed, round/oval cavity containing pus and pieces of dead bone (sequestra) surrounded sclerosis - Most commonly seen in tibial / femoral metaphysis *may occur in epiphysis / cuboidal bone (eg: calcaneum) - Metaphyseal lesion cause no / little periosteal reaction - Diaphyseal lesion may be associated with periosteal new bone formation and marked coical thickening . ref : maheswari9th ed", "cop": 2, "opa": "Subungual infection", "opb": "chronic osteomyelitis", "opc": "web space infection", "opd": "infected hematoma", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "be63713b-634e-4f36-8534-f2c5e3c171bf", "choice_type": "single"} {"question": "Superficial branch of ulnar nerve supplies", "exp": "Superficial branch of ulnar nerve supplies palmaris brevis and gives digital branches to medial 1 1/2 digits including medial 1 1/2 nail beds till the interphalangeal joints . Opponens pollicis is supplied by the recurrent branch of median nerve . Adductor pollicis and abductor digiti minimi is supplied by the deep branch of ulnar nerve . B D Chaurasia 7th edition Page no : 124", "cop": 1, "opa": "Palmaris brevis", "opb": "Opponens pollicis", "opc": "Adductor pollicis", "opd": "Abductor digiti minimi", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "6944746a-9bf7-47fc-92e6-8980c1fb6f3e", "choice_type": "single"} {"question": "Sacrotuberous and sacrospinous ligaments attach sacrum to", "exp": "The sacrotuberous ligament is a strong broad band of fibrous tissue. It has broad upper end and narrow lower lateral end.Upper end is attached from above downward to posterior superior iliac spine, posterior inferior iliac spine, lower pa of posterior surface and lateral border of sacrum and adjoining pa of coccyx. The lower end is attached to medial margin of ischial tuberosity. Some of the fibres from lower end continue on to the ramus of ischium as the falciform process.The sacrospinous ligament is a triangular sheet of fibrous tissue with its apex attached laterally to the ischial spine and base medially to the side of sacrum and coccyx.The sacrospinous and sacrotuberous ligaments conve the greater and lesser sciatic notches of the hip bone into greater and lesser sciatic foramina-the two impoant exits from the pelvis.Reference: Textbook of anatomy, Abdomen and Lower limb, Vishram Singh, 2nd edition, page no.204", "cop": 2, "opa": "Ilium", "opb": "Ischium", "opc": "Pubis", "opd": "Lumbar veebrae", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "6e0ad2e1-b1a9-4f4a-a632-968295fd39d7", "choice_type": "single"} {"question": "Teratospermia refers to", "exp": "Increased abnormal forms Teratospermia -----increased number of abnormal sperms. Regarding sperm morphology, the WHO criteria as described in 2010 state that a sample is normal (samples from men whose paners had a pregnancy in the last 12 months) if 4% (or 5th centile) or more of the observed sperm have normal morphology. Aspermia-------------absence of semen Azoospermia--------absence of sperms in semen. Total sperm count, or total sperm number, is the total number of spermatozoa in the entire ejaculate. By WHO, lower reference limit (2.5th percentile) is 39 million per ejaculate Oligospermia-------decreased sperm count Asthenospermia----decreased motility of sperms. The World Health Organization has a value of 50% and this must be measured within 60 minutes of collection Necrospermia-------increased number of dead sperms.", "cop": 1, "opa": "Increased abnormal forms", "opb": "Decreased count", "opc": "Decreased motility", "opd": "Absent semen", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "d1c7be9f-2ead-455a-a2f6-c95cf205d8ad", "choice_type": "single"} {"question": "Superior orbital fissure synd. includes", "exp": "superior orbital fissure * lateral pa lacrimal and frontal nerves, trochlear nerve, superior ophthalmic vein, meningeal branch of lacrimal aery, anastomotic branch of middle meningeal aery which anastomoses with recurrent branch of lacrimal aery. *middle pa upper and lower divisions of oculomotor nerve, nasociliary nerve, abducent nerve * medial pa inferior ophthalmic vein, sympathetic nerve from plexus around internal carotid aery Ref BDC volume 3; 6th edition pg 56", "cop": 1, "opa": "3, 4, 5, 6 cranial nr", "opb": "3, 2, 4, 5 cranial nr", "opc": "2, 6, 3 cranial nr", "opd": "2, 5, 6 cranial nr", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "5f2f731d-2897-4ecc-93d2-080cc6386e0d", "choice_type": "single"} {"question": "Schwannoma of 8th cranial nerve site is", "exp": null, "cop": 3, "opa": "Intra — petrous", "opb": "Intracanalicular", "opc": "Cisternal", "opd": "Parotid", "subject_name": "Anatomy", "topic_name": null, "id": "23970137-e3dd-46f2-b22b-b8e1e622bec3", "choice_type": "single"} {"question": "Vascular inflow occlusion of the liver is by", "exp": "Pringle Maneuver (Total inflow occlusion) Total clamping of the hepatic pedicle, by placing an atraumatic clamp across the foramen of Winslow Appropriate sized vascular clamp or loop snare easily controls hemorrhage from either the poal vein or the hepatic aeries Inflow occlusion durations of upto 39 minutes can be tolerated safely in cirrhotic livers and possibly upto 60 minutes in early disease If Prolonged occlusion is required, intermittent clamping can be used with repeated clamping of 10-20 minutes duration, each followed by 5 minutes declamping Ref: Sabiston 20th edition Pgno : 439", "cop": 4, "opa": "Clamping the hepatic aery", "opb": "Occluding the poal vein", "opc": "Clamping the hepatic veins", "opd": "The pringle maneuver", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "58dd7ad6-7cf2-4656-b90c-27862a094270", "choice_type": "single"} {"question": "Yoke muscle of right lateral rectus is", "exp": "(A) Left medial rectus[?]Yoke muscle (contra-lateral synergists):Reference to muscles which are primary muscles (one from each eye) that accomplish (contract) a given version.YOKE MUSCLES IN CARDINAL POSITIONS OF GAZE* Eyes up & rightRSR & LIO* Eyes up & leftLSR & RIO* Eyes rightRLR & LMR* Eyes leftLLR & RMR* Eyes down & rightRIR & LSO* Eyes down & leftLIR & RSOContralaterally paired extra-ocular muscles that work synergistically to direct the gaze in a given direction.For example, in directing the gaze to the right, the right lateral rectus and left medial rectus operate together as yoke muscles. ACTION OF EXTRA-OCULAR MUSCLESBeing approximately horizontal, when the visual axis is in its primary position, i.e. directed to the horizon, they rotate the eye medially (adduction) or laterally (abduction) about an imaginary vertical axis.They are antagonists.Visual axis can be swept through a horizontal arc by reciprocal adjustment of their lengths.When, as is usual, both eyes are involved, the medial & lateral recti of each eye either can adjust both visual axes in a conjugate movement from point to point at infinity (their axes remaining parallel), or they can converge or diverge the axes to or from nearer or more distant objects of attention in the visual field.Medial & lateral recti do not rotate the eye around its horizontal axis and so cannot elevate or depress the visual axes as gaze is transferred from nearer to more distant objects or the reverse.Normally, movements of the two eyes are harmoniously coordinated.Such coordinated movements of both eyes are called conjugate ocular movements.Conjugate movements are usually horizontal or vertical, but oblique conjugate movements may also occur.Dissociated movements of the two eyes are known as disjunctive movements (skew deviation).Levator palpebrae superioris elevates the upper lid, & its antagonist is the palpebral part of orbicularis oculi.", "cop": 1, "opa": "Left medial rectus", "opb": "Left superior rectus", "opc": "Left lateral rectus", "opd": "Left inferior oblique", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "62c2545a-093d-4a1f-9471-3dc23f8cab33", "choice_type": "single"} {"question": "Canal of Herring are seen in", "exp": null, "cop": 2, "opa": "Spleen", "opb": "Liver", "opc": "Kidney", "opd": "Thymus", "subject_name": "Anatomy", "topic_name": null, "id": "cd91cf60-1af1-40c0-b4f7-de826aef765c", "choice_type": "single"} {"question": "Diagnostic investigation in carcinoma pan2", "exp": "MDCT Diagnostic investigation in carcinoma pancreas is MDCT MDCT is investigation of choice for evaluation of lesions arising in the pancreas Investigation of choice for diagnosis, staging and follow up in CA pancreas : MDCT Ref:Sabiston 20th edition Pgno :1544", "cop": 1, "opa": "MDCT", "opb": "PET scan", "opc": "ERCP", "opd": "MRCP", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "158f54f0-0c35-4013-b45c-4b8995c0dae3", "choice_type": "single"} {"question": "Azygos vein", "exp": "(Ascends through the aortic opening in the diaphragm) (213-BDC-l) (128-Snell 7th)AZYGOS VEIN - The origin of the azygos vein is variable. It is often formed by the union of the right ascending lumbar vein and the right subcostal vein. It ascends through the aortic opening in the diaphragm on the right side of the aorta to the level of the fifth thoracic vertebra. Here it arches forward above the root of the right lung to empty into the posterior surface of the superior vena-cava.* In obstruction of the superior or inferior vena cava, the azygos veins provide an alternate pathway for the return of venous blood to the right atrium of the heart.", "cop": 4, "opa": "Formed by arch of aorta", "opb": "Opens into inferior vena cava", "opc": "Arches the groove of the left lung", "opd": "Ascends through the aortic opening in the diaphragm", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "8f1171d8-622f-4700-8749-3148c0b630b2", "choice_type": "single"} {"question": "Nerve emerging through the trapezoid body of pons is", "exp": "The trapezoid body is located in the caudal pons, or more specifically the pontine tegmentum. The trapezoid body is pa of the auditory pathway where some of the axons coming from the cochlear nucleus decussate, or cross over to the other side before traveling on to the superior olivary nucleus. This is believed to help with localization of sound. (Ref: vishram Singh textbook of clinical neuroanatomy second edition pg 80)", "cop": 4, "opa": "Trigeminal nerve", "opb": "Abducens nerve", "opc": "Facial nerve", "opd": "Cochlear nerve", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "8c8c9d42-e137-4e0a-b1d2-103d56afae3c", "choice_type": "single"} {"question": "Parotid duct opens at", "exp": null, "cop": 3, "opa": "1st PM", "opb": "1st molar", "opc": "2nd upper molar", "opd": "2nd lower molar", "subject_name": "Anatomy", "topic_name": null, "id": "d7fc2573-7a4a-4902-82c2-bb4970ef708d", "choice_type": "single"} {"question": "LE cell phenomenon is seen in", "exp": "Ref Robbins 9/e p222 LE cell or hematoxylin body is a phagocytic leukocyte that has engulfed the denatured nucleus of an injured cell", "cop": 2, "opa": "Lymphocytes", "opb": "Neutrophils", "opc": "Monocytes", "opd": "Eosinophil", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e55c52f1-26a8-4750-8b3a-66709dd25c93", "choice_type": "single"} {"question": "Gene for Wilms tumor iis located on", "exp": "characterized by Wilms tumor, aniridia, genital anomalies, and mental retardation. Their lifetime risk of developing Wilms tumor is approximately 33%. Individuals with WAGR syndrome carry constitutional (germline) deletions of 11p13. Studies on these patients led to the identification of the first Wilms tumor-associated gene, WT1, and a contiguously deleted autosomal dominant gene for aniridia, PAX6, both located on chromosome 11p13. Patients with deletions restricted to PAX6, with normal WT1 function, develop sporadic aniridia, but they are not at increased risk for Wilms tumors Refer Robbins 9/e 481", "cop": 3, "opa": "Chromosome 1", "opb": "Chromosome 10", "opc": "Chromosome 11", "opd": "Chromosome 12", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "81fd3ae7-1e8a-4e82-b1ac-977b6e781419", "choice_type": "single"} {"question": "Albumino cytologic dissoscition occurs in cases of", "exp": "Gullian Barre syndrome What are the symptoms of Guillain-Barre syndrome? tingling or prickling sensations in your fingers and toes. muscle weakness in your legs that travels to your upper body and gets worse over time. difficulty walking steadily. difficulty moving your eyes or face, talking, chewing, or swallowing. severe lower back pain. Refer Robbins page no 1231", "cop": 1, "opa": "Gullian Barre syndrome", "opb": "TB meningitis", "opc": "Motor Neuron disease", "opd": "Demyelinating disorder", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "a6e02015-cb1f-412c-8e66-7213fa18608a", "choice_type": "single"} {"question": "Most common liver cell tumor in those on OCP's", "exp": "Hepatic adenoma It is a benign proliferative disorder of hepatocytes Predominantly found in young women (20-40yrs) associated with OCP's Usually single ( multiple lesions in 12-30%)", "cop": 2, "opa": "HCC", "opb": "Liver cell adenoma", "opc": "Bile duct adenoma", "opd": "FNH", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ac7811fd-ac56-42c8-a33e-c5997d2f3c6d", "choice_type": "single"} {"question": "Best investigation of bilhemia is", "exp": "Bilhemia It is an extremely rare condition Bile flows into the blood stream either through the hepatic veins or poal vein branches Etiology High intra biliary pressure, exceeding that of venous system (CBD stone). Gallstones eroding into the poal vein. Accidental or iotrogenic trauma Clinical features Rapidly increasing jaundice, marked direct hyperbilirubinemia The condition can be fatal secondary to embolization of large amounts of bile into the lungs Most often, bile flow is low and the Fistulas Spontaneously closes Diagnosis ERCP is investigation of choice (Diagnostic and therapeutic) Treatment Treatment is directed at lowering intra biliary pressure either through stents or sphincterectomy Ref : Sabiston 20th edition Pgno : 1473-1474", "cop": 1, "opa": "ERCP", "opb": "MRCP", "opc": "CT", "opd": "EUS", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "c942c698-1b92-43e6-9783-2f26b027ae31", "choice_type": "single"} {"question": "Eversion of foot is produced by", "exp": "Eversion: movement in which the lateral border of the foot is elevated so that the sole faces laterally. Inversion: movement in which the medial border of the foot is elevated so that the sole faces medially. In eversion and inversion, the entire pa of the foot below the talus moves together. Inversion is accompanied by plantar flexion of the foot and adduction of the forefoot. Eversion is accompanied by the dorsiflexion of the foot and adduction of the forefoot. JOINTS TAKING PA:-Subtalar Talocalcaneonavicular Transverse talar AXIS:-These movements take place around an oblique axis which runs forwards, upwards and medially, passing from the back of the calcaneum, through sinus tarsi,to emerge at the superomedial aspect of the neck of the talus.The obliquity of the axis pay accounts for the adduction, abduction, plantar flexion and dorsiflexion which are associated with these movements. RANGE:-Inversion is more free than eversion The range of movements is increased in plantar flexion. MUSCLES PRODUCING MOVEMENTS:- Main Inversion Tibialis anterior Tibialis posterior FHL FDL Eversion Peroneus longus Peroneus brevis {Reference:BDC 6E}", "cop": 3, "opa": "Tibialis anterior", "opb": "Tibialis posterior", "opc": "Peroneus teius", "opd": "Peroneus longus", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "a3f69877-d0ce-4d64-926f-b2a3a8d33013", "choice_type": "single"} {"question": ".Drug of choice for alcohol withdrawal", "exp": "Treatment of alcohol dependence comprises 2 steps namely detoxification and de addiction DETOXIFICATION Detoxification implies removal of the toxic substance from the body, this can be done by using a drug similar to alcohol and thus benzodiazepine is chosen. This is the main drug used in treatment of alcohol withdrawal despite the problem being simple withdrawal, rum fits or delirium tremens IF LIVER FUNCTION IS WITHIN NORMAL LIMITS CHOOSE CHLORDIAZEPOXIDE, AS IT HAS A SIMILAR STRUCTURAL FORMULA LIKE ALCOHOL IF LIVER FUNCTION IS ABNORMAL CHOOSE LORAZEPAM, AS IT DOES NOT WORSEN LIVER DERANGEMENTS FRONT LOADING=====patient is loaded with benzodiazepines SYMPTOM TRIGGER=== benzodiazepines is offered only as and when the withdrawal symptom arises FIXED DOSAGE====== regular fixed dosage of benzodiazepine is given in divided doses and slowly tapered so that the patient is not on any drugs by the end of 2 weeks Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, pf no.625", "cop": 3, "opa": "Disulfiram", "opb": "Chlormethazole", "opc": "Chlordiazepoxide", "opd": "Buspirone", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "a44c79e7-d1ba-4188-a712-72f0f2cafc0c", "choice_type": "single"} {"question": "Exposure of left subclan aery by supraclavicular approach does not require cutting of", "exp": "Scalenus medius is located posterior to the subclan aery. Hence there is no need to cut this to expose the subclan aery. Ref - Bdc 6th e Vol 3 pg165,166 , pubmed.com", "cop": 3, "opa": "Sternocleidomastoid", "opb": "Scalenus anterior", "opc": "Scalenus medius", "opd": "Omohyoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6e27151a-0494-4c2d-82d1-f7c6c7f9af36", "choice_type": "single"} {"question": "Aery of hindgut is", "exp": "Aerial supply of hindgut is inferior mesenteric aery imageref - researchgate.net", "cop": 3, "opa": "Descending aery", "opb": "Superior mesenteric aery", "opc": "Inferior mesenteric aery", "opd": "Coeliac trunk", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "fd179e72-cdfb-4cab-bf0e-7696a5c1a5fe", "choice_type": "single"} {"question": "Ecadherin Gene deficiency is seen in", "exp": "ref Robbins 8/e p96; 9/e p297 Cadherins are derived from the \"calcium dependant adherence protein\".it paicipate in interaction between cells of same type The linkage of cadherins with the cytoskeleton occurs through catenins .the cell to cell interaction mediated by cadherins and catenins play a differentiation and account for the inhibition of cell proliferation that occurs when cultured normal cells contact each other", "cop": 1, "opa": "Gastric cancer", "opb": "Intestinal cancer", "opc": "Thyroid cancer", "opd": "Pancreatic cancer", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7893263a-fe03-4617-bfcd-b8b7230d469c", "choice_type": "single"} {"question": "Tubercles of Montgomery are present in", "exp": "Montgomery's glands or Montgomery Tubercles are the large sebaceous and rudimentary milk glands present in the areola surrounding the nipple of the female breast.", "cop": 4, "opa": "Lung", "opb": "Duodenum", "opc": "Liver", "opd": "Breast", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "37d1eb11-c2f2-43d7-8772-15568eaad0b2", "choice_type": "single"} {"question": "40yr old male patient having pain with daily morning stiffness of spine for 30 minutes and reduced chest movements. Most probable diagnosis is", "exp": "The information in question are 40yr male Morning stiffness in spine Limited chest expansion *****all fit into clinical criteria for diagnosis of Ankylosing spondylitis x ray of ankylosing spondylitis -BAMBOO SPINE AS is a chronic, progressive immune-mediated inflammatory disorder that results in ankylosis of the veebral column and sacroiliac joints . * The spine and sacroiliac joints are the common affected sites -- Chronic spinal inflammation (spondylitis) can lead to fusion of veebrae (ankylosis) . Characteristic Pathologic Features : * Chronic inflammation in: - Axial structures (sacroiliac joint, spine, anterior chest wall, shoulder and hip) - Possibly large peripheral joints, mainly at the lower limbs (oligoahritis) - Entheses (enthesitis) * Bone formation paicularly in the axial joints Axial manifestations: * Chronic low back pain * With or without buttock pain * Inflammatory characteristics: - Occurs at night (second pa) - Sleep disturbance - Morning stiffness * Limited lumbar motion * Onset before age of 40 years Refer maheswari 9th ed", "cop": 1, "opa": "Ankylosing spondylitis", "opb": "Rheumatoid ahritis", "opc": "Gouty ahritis", "opd": "Osteoahritis", "subject_name": "Anatomy", "topic_name": null, "id": "c70d571f-19d8-440d-af6f-f617c919a426", "choice_type": "single"} {"question": "Nerve supplying Gemellus inferior", "exp": "Nerve to Obturator internus supplies obturator internus and Gemellus superior.\nNerve to Quadratus femoris supplies Quadratus femoris and Gemellus inferior", "cop": 4, "opa": "Nerve to Obturator internus", "opb": "Superior gluteal nerve", "opc": "Inferior gluteal nerve", "opd": "Nerve to Quadratus femoris", "subject_name": "Anatomy", "topic_name": null, "id": "84658904-3855-47b5-9307-99efb9d90b0d", "choice_type": "single"} {"question": "An adult old man gets burn injury to his hands .over few weeks .the burner skin heals without the need for skin grafting . The most impoant critical factor responsible for rapid healing in this case is", "exp": "ref baley and love 23/e p189 Burn wounds of the skin result in a rupture of the cutaneous barrier that can have serious consequences such as loss of proteins and body fluids, infection, and death (Figure 65.1). Moreover, chronic wounds or improper scarring and the development of skin cancers (Owens and Watt, 2003; Perez-Losada and Balmain, 2003). A first-degree burn wound affects only the epidermis and heals spontaneously without scarring; the reconstitution of epidermal integrity results from the migration and the proliferation of ", "cop": 1, "opa": "Remnant skin appendages", "opb": "Underlying connective tissue", "opc": "Minimal Prema and erythema", "opd": "Granulation tissue", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ce3aa6ef-5eb5-4a94-93a3-8e2f5ec7875e", "choice_type": "single"} {"question": "Roots involved in Erb's palsy are", "exp": "Erb's point is formed by the roots of C5 and C6, anterior and posterior divisions of upper trunk, suprascapular nerve and nerve to subclavius muscle. So the nerve root involved in Erb's palsy is C5 and C6.", "cop": 2, "opa": "Posterior primary rami of C6- C7", "opb": "Anterior primary rani of C5-C6", "opc": "Posterior primary rami of C8-T1", "opd": "Posterior primary rami of C7-C8", "subject_name": "Anatomy", "topic_name": null, "id": "e37aaab2-3cec-4824-b0fd-f53de98c4748", "choice_type": "single"} {"question": "The type of Epithelium associated with the Vermilion Zone of the Lips is", "exp": "The External Aspect and Vermilion Zone of the Lips are covered by thin skin, which contains a Stratified Squamous Keratinized epithelium.", "cop": 3, "opa": "Stratified Squamous Non keratinized.", "opb": "PseudoStratified Ciliated Columnar", "opc": "Stratified Squamous Keratinized", "opd": "Stratified Cuboidal", "subject_name": "Anatomy", "topic_name": "Systemic histology", "id": "01a361ba-2f83-4bd1-80db-909032cfeaeb", "choice_type": "single"} {"question": "Epithelium covering the Bowman's capsule", "exp": "Simple squamous epithelium's typical locations\n\nVascular system (endothelium) \nBody cavities (mesothelium)\nBowman’s capsule (kidney)\nRespiratory spaces in lung", "cop": 1, "opa": "Simple squamous epithelium", "opb": "Simple cuboidal epithelium", "opc": "Simple columnar epithelium", "opd": "Stratified squamous epithelium", "subject_name": "Anatomy", "topic_name": null, "id": "fc50b4ad-b8a4-4732-a0c4-bd02223bd93c", "choice_type": "single"} {"question": "Most essential medicines are formulated as", "exp": "Essential medicines are those that satisfy the priority health care needs of the population. Criteria for selection of essential medicines Essential medicines are selected with due regard to disease prevalence and public health relevance, evidence of clinical efficacy and safety, and comparative costs and cost-effectiveness. Refer 7/e p24", "cop": 2, "opa": "No compound", "opb": "Single compound", "opc": "Multiple compound", "opd": "Fixed dose combination", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "55378779-7c60-44a5-b00e-ded9707471e9", "choice_type": "single"} {"question": "Dementia in ICD 10 is classified under", "exp": "ICD CHAPTERS ICD is a text book for classification of psychiatric disorders. The below table comprises chapter numbers dealing with various psychiatric disorders. Ref.Kaplon and Sadock, synopsis of Psychiatry, 10th edition", "cop": 1, "opa": "F00", "opb": "F10", "opc": "F20", "opd": "F30", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "aa0a4737-eed2-4bcd-ac64-ccae94781100", "choice_type": "single"} {"question": "Shock lung is characterized by", "exp": "ref Robbins 7/r p715,9/e p134 Harrison 17/e p1680_1681 The cellular and tissue effects of shock are essentially those of hypoxic injury (Chapter 1) and are caused by a combina- tion of hypoperfusion and microvascular thrombosis. Although any organ can be affected, brain, hea, kidneys, adrenals, and gastrointestinal tract are most commonly involved. Fibrin thrombi can form in any tissue but typically are most readily visualized in kidney glomeruli. Adrenal cor- tical cell lipid depletion is akin to that seen in all forms of stress and reflects increased utilization of stored lipids for steroid synthesis. While the lungs are resistant to hypoxic injury in hypovolemic shock occurring after hemorrhage, sepsis or trauma can precipitate diffuse alveolar damage (Chapter 12), leading to so-called shock lung.", "cop": 4, "opa": "Alveolar proteinosis", "opb": "Bronchiolitis obliterans", "opc": "Diffuse pulmonary haemorrhage", "opd": "Diffuse alveolar damage", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3b45f0a8-8f4f-4173-9587-f2fb92bd6471", "choice_type": "single"} {"question": "Most sensitive investigation of pancreatic carcinoma is", "exp": "Investigation of choice for carcinoma pancreas is MDCT Currently CT is probably the single most versatile and cost effective tool for diagnosis of pancreatic cancer Ref: CSDT 11th edition Pgno :645", "cop": 4, "opa": "Angiography", "opb": "ERCP", "opc": "Ultrasound", "opd": "CT scan", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8aab632f-c0ea-45e0-af5a-120abcfee8e7", "choice_type": "single"} {"question": "Adhesion of platelet to collagen is due to", "exp": "Ref Robbins 9/e p117 Von Willebrand Factor's primary function is binding to other proteins, in paicular factor VIII, and it is impoant in platelet adhesion to wound sites. It is not an enzyme and, thus, has no catalytic activity. VWF binds to a number of cells and molecules. The most impoant ones are: Factor VIII is bound to VWF while inactive in circulation; factor VIII degrades rapidly when not bound to VWF. Factor VIII is released from VWF by the action of thrombin. In the absence of VWF, factor VIII has a half-life of 1-2 hours; when carried by intact VWF, factor VIII has a half-life of 8-12 hours. VWF binds to collagen, e.g., when collagen is exposed beneath endothelial cells due to damage occurring to the blood vessel. Endothelium also releases VWF which forms additional links between the platelets' glycoprotein Ib/IX/V and the collagen fibrils", "cop": 3, "opa": "Factor 9", "opb": "Fibrinogen", "opc": "Von willebrand factor", "opd": "Fibrionectin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8d84b07f-63da-472e-a6d6-3aa342aecd44", "choice_type": "single"} {"question": "Muscle not supplied by median nerve REPEATED", "exp": "Opponens pollicis, abductor pollicis brevis and first lumbrical is supplied by the recurrent branch of median nerve in palm.Extensor pollicis brevis is supplied by the deep division of radial nerve in the forearm.B D Chaurasia 7th edition Page no: 182", "cop": 1, "opa": "Opponens pollicis", "opb": "Abductor pollicis brevis", "opc": "Extensor pollicis brevis", "opd": "First lumbrical", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "138478ef-51c8-487b-ac52-6f8e45cf9e2c", "choice_type": "single"} {"question": "Gluteus maximus is supplied by", "exp": "INFERIOR GLUTEAL NERVE:- Root value:L5,S1,S2Course: Enters gluteal region through greater sciatic notch below pyriformis muscle.Branches: Gluteus maximus.It is the sole supply to the large antigravity, postural muscle with red fibers, responsible for extending hip joint. SUPERIOR GLUTEAL NERVE Root value: L4,L5,S1Course: enters the gluteal region through greater sciatic notch above pyriformis muscle. Runs between gluteus medius and gluteus minimus to end in tensor fascia lata. Branches :-it supplies 1. Gluteus medius 2. Gluteus minimus3. Tensor fascia lata SCIATIC NERVE:-Root value: L4,L5,S1,S2,S3 ventral rami Thickest nerve in the body.Terminal branch of lumbosacral plexus.Tibial pa and common peroneal pa. Tibial pa:ventral division of ventral rami of L4,L5,S1,S2,S3.Common peroneal pa: dorsal division of ventral rami of L4, L5, S1, S2. Course: arises in pelvis.Leaves pelvis by passing through greater sciatic foramen below pyriformis to enter gluteal region.In gluteal region, it lies deep to gluteus maximus and crosses superior and inferior gamellus, obturator internus, quadratus femoris to reach thigh.During its sho course it lies between ischial tuberosity and greater trochanter.Gives no branches in gluteal region. Branches:--Muscular1. From tibial pa: semitendinosus, semimembranosus, long head of biceps femoris, ischial pa of Adductor Magnus.2. From common peroneal :Sho head of biceps femoris. Aicular: hip joint Terminal:tibial and common peroneal. {Reference: BDC 6E pg no.173}", "cop": 2, "opa": "Superior gluteal nerve", "opb": "Inferior gluteal nerve", "opc": "Nerve to quadratus femoris", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "0550bd81-4b20-43eb-b17d-8bfae6955f0d", "choice_type": "single"} {"question": "Common site of fracture in tibia is", "exp": "The tibia is commonly fractured at the junction of upper two-thirds and lower one-third of the shaft as the shaft is most slender here. Such fractures may unite slowly, or may not unite at all as the blood supply to this pa of the bone is poor. This may also be caused by tearing of the nutrient aery.Ref: Chaurasia; Volume 2; 6th edition; Page no: 25", "cop": 2, "opa": "Upper one-third", "opb": "Junction of upper two-thirds and lower one-third", "opc": "Lower one-third", "opd": "Middle one-third", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "6ae3569c-ddb1-4b9e-8a38-071964a1382a", "choice_type": "single"} {"question": "charecterstic feuture of anorexia nervosa is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "redtricting food", "opb": "dyslipedima", "opc": "overweght", "opd": "hypeension", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "f086b917-0634-42fc-b854-d644496d1a0a", "choice_type": "single"} {"question": "Mode of injury of a cotton fracture is", "exp": "Cotton fracture is due to abduction and external rotational injury. It is also known as TRIMALLEOLAR FRACTURE. There is fracture of the medial,lateral and posterior malleolus. It more often requires open reduction and internal fixation.", "cop": 3, "opa": "Adduction and external rotation", "opb": "Abduction and internal rotation", "opc": "Abduction and external rotation", "opd": "Adduction and internal rotation", "subject_name": "Anatomy", "topic_name": "Thigh, Knee,Leg,Foot & Ankle injuries", "id": "fa6ff221-0bb8-490c-8d73-ac4a06c03dd9", "choice_type": "single"} {"question": "any behaviou that is followed by reward is increased, this is", "exp": "Behavioral therapy is learning given by BF Skinner , according to him all behaviors are learned phenomenon and thus can be unlearned Positive reinforcement a type of reinforcement when a behavior is rewarded there is more chance that the behavior is repeated Negative reinforcement is that when a behavior is done and an aversive response is removed, the behavior is repeated. When I go and meet my girlfriend, she checks my messages and picks up fight (aversive response) suddenly I delete all messages one day and that day there was no fight (no aversive response) then that behavior is repeated (delete all messages before meeting my girlfriend) Extinction is the type of reinforcement where a behavior is done and a rewarding response is removed the chance is that behavior will not be repeated A child likes to play with children( reward) but when the child fights with other children( undesirable behavior) the child will be removed from playing( removing a reward) , then the child stops fighting with other children( reduction of undesirable behaviour) Ref. kaplon and sadock synopsis, 11 th edition, pg no. 845", "cop": 2, "opa": "punishment", "opb": "positive reinforcrmrnt", "opc": "omission", "opd": "negative reinforcement", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a4246723-9bb1-46fc-8e6f-0b9cc2b56cc9", "choice_type": "single"} {"question": "An anterolaternal corodotomy relieving pain in right leg is effective because it interrupts the", "exp": "C i.e. Left lateral spinothalmic tract The anterior/ ventral - spinothalmic tract carries crude touch and pressueQ from opposite half of body; whereas lateralspinothalmic tract carries pain and temperature from the opposite half of body. Therefore any lesion in lateral spinothalmic tract will result in loss of pain and temperature sensation contralaterally below the level of lesion; and lesion of anterior spinothalmic tract will 1/ t loss of crude touch & pressure sensation contralaterally.", "cop": 3, "opa": "Left dorsal column", "opb": "Left ventral spinothalmic tract", "opc": "Left lateral spinothalmic tract", "opd": "Right lateral spinothalmic tract", "subject_name": "Anatomy", "topic_name": null, "id": "048b366b-609e-4fe1-841e-7fbacdaf286a", "choice_type": "single"} {"question": "Tone of the anal sphincter in maintained by", "exp": "The anal sphincters and puborectalis are the primary muscles responsible for continence. There are two sphincters: the internal anal sphincter, and the external anal sphincter. The internal sphincter is responsible for 85% of the resting muscle tone and is involuntary. ref - BDC 6e vol2 pg413-416", "cop": 3, "opa": "Nervi erigentes", "opb": "Inferior hypogastric plexus", "opc": "Inferior rectal nerve", "opd": "Pelvic splanchnic nerves", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "50627552-1a6d-4791-87dd-11d154b6f1b0", "choice_type": "single"} {"question": "Superficial incision on posterior triangle of neck leads to", "exp": "Ans is 'a' i.e. difficulty in shrugging of shoulder Nerves in the posterior triangle of neck (only motor nerves)Spinal accessory nerveTwo small branches to levator scapulae(C3,4)Nerve to RhomboideNerve to serratus anteriorNerve to subclaviusSuprascapular nerveWhen a superficial incision is made in the post triangle, the nerve most likely to be injured is spinal accessory nerve, because it runs through a tunnel in the fascia forming the roof of triangle.Rest all nerves are either deep or have a very small course in the lower part of the triangleSpinal accessory nerve supplies 2 muscles -Trapezius andsternocleidomastoidAction of Trapezius* :Elevation of scapulaRetraction of scapulaRotation of scapulaAction of sternocleidomastoid* :Turns the face to opposite side *Tilts the head towards the same shoulder.When SCM of both sides contracts draws the head forwards.", "cop": 1, "opa": "Difficulty in shrugging of shoulder", "opb": "Difficulty in start of abduction", "opc": "Difficulty in rotation of face towards the same side", "opd": "Difficulty in flexion", "subject_name": "Anatomy", "topic_name": "Triangles of Neck", "id": "3b0eea6f-ffe9-4bb1-94b4-9412aba07a8e", "choice_type": "single"} {"question": "Tropical spastic paraparesis is caused by", "exp": "Oncogenic RNA Viruses The study of oncogenic retroviruses in animals has pro- vided spectacular insights into the genetic basis of cancer. However, only one retrovirus, the human T cell lympho- tropic virus-1 (HTLV-1), has been demonstrated to cause cancer in humans. HTLV-1 is associated with a form of T cell leukemia/lymphoma that is endemic in ceain pas of Japan and the Caribbean basin but is found sporadically elsewhere, including the United States. Similar to the human immunodeficiency virus (HIV), HTLV-1 has tropism for CD4+ T cells, and this subset of T cells is the major target for neoplastic transformation. Human infec- tion requires transmission of infected T cells through sexual intercourse, blood products, or breastfeeding. Leukemia develops only in about 3% to 5% of infected persons after a long latent period of 20 to 50 years. There is little doubt that HTLV-1 infection of T lympho- cytes is necessary for leukemogenesis, but the molecular mechanisms of transformation are not clear. The HTLV-1 genome does not contain a viral oncogene, and in contrast with ceain animal retroviruses, no consistent integration site next to a cellular oncogene has been discovered. Indeed, the long latency period between initial infection and devel- opment of disease suggests a multistep process, during which many oncogenic mutations are accumulated. The genome of HTLV-1 contains, in addition to the usual retroviral genes, a unique region called pX. This region contains several genes, including one called TAX. The TAX protein has been shown to be necessary and sufficient for cellular transformation. By interacting with several transcription factors, such as NF-kB, the TAX protein can transactivate the expression of genes that encode cytokines, cytokine receptors, and costimulatory molecules. This inappropriate gene expression leads to autocrine signaling loops and increased activation of promitogenic signaling cascades. Fuhermore, TAX can drive progression through the cell cycle by directly binding to and activating cyclins. In addition, TAX can repress the function of several tumor suppressor genes that control the cell cycle, including CDKN2A/p16 and TP53. From these and other observa- tions, the following scenario is emerging (Fig. 5-31): The TAX gene turns on several cytokine genes and their recep- tors (e.g., the interleukins IL-2 and IL-2R and IL-15 and IL-15R), setting up an autocrine system that drives T cell proliferation. Of these cytokines, IL-15 seems to be more impoant, but much remains to be defined. Additionally, a parallel paracrine pathway is activated by increased pro- duction of granulocyte-macrophage colony-stimulating factor, which stimulates neighboring macrophages to produce other T cell mitogens. Initially, the T cell prolifera- tion is polyclonal, because the virus infects many cells, but because of TAX-based inactivation of tumor suppressor genes such as TP53, the proliferating T cells are at increased risk for secondary transforming events (mutations), which lead ultimately to the outgrowth of a monoclonal neoplas- tic T cell population.", "cop": 1, "opa": "Human T cell lymphotropic virus", "opb": "Hepatitis B virus", "opc": "Human immunodeficiency virus", "opd": "Epstein Barr virus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b60ffa4d-7542-4a08-acd5-0e850971df52", "choice_type": "single"} {"question": "Common Facial vein is formed by the union of", "exp": "The scalp on each side of the midline is drained by five veins. The veins of the scalp accompany the arteries and have similar names. These are as follows:\n\nSupratrochlear and supraorbital veins: They join each other at the medial angle of the eye to form the angular vein, which continues downwards as the facial vein behind the facial artery.\nSuperficial temporal vein: It descends in front of tragus to enter the parotid gland where it joins the maxillary vein to form the retromandibular vein, which terminates by dividing into anterior and posterior divisions. The anterior division unites with the facial vein to form common facial vein, which drains into the internal jugular vein.\nPosterior auricular vein: It descends behind the auricle and  unites with the posterior division of the retromandibular vein to form the external jugular vein, which drains into the subclavian vein.\nOccipital vein: It terminates in the suboccipital venous plexus.", "cop": 4, "opa": "Anterior facial and posterior facial veins", "opb": "Anterior facial and posterior auricular veins", "opc": "Anterior facial and maxillary veins", "opd": "Anterior facial and anterior branch of the posterior facial vein", "subject_name": "Anatomy", "topic_name": null, "id": "c12899ab-803e-43df-97e7-90da885a75ad", "choice_type": "single"} {"question": "Toughest layer in esophagus is", "exp": "The wall of oesophagus has the usual four layers viz., mucosa, submucosa, muscularis externa and an external adventitia. The oesophagus does not have a serous covering except over a sho length near its lower end. The Mucosa - The mucous membrane of the oesophagus shows several longitudinal folds that disappear when the tube is distended. The mucosa is lined by stratified squamous epithelium, which is normally not keratinised. Occasional melanocytes and endocrine cells are present. A columnar epithelium, similar to that lining the cardiac end of the stomach, may extend for some distance into the abdominal pa of the oesophagus. Finger-like processes (or papillae) of the connective tissue of the lamina propria project into the epithelial layer (just like dermal papillae). This helps to prevent separation of epithelium from underlying connective tissue. At the upper and lower ends of the oesophagus some tubuloalveolar mucous glands are present in the lamina propria. The muscularis mucosae is absent or poorly developed in the upper pa of the oesophagus. It is distinct in the lower pa of the oesophagus, and is thickest near the eosophagogastric junction. It consists chiefly of longitudinal muscular fibres, but a few circular fibres are also present. The Submucosa - The only special feature of the submucosa is the presence of compound tubuloalveolar mucous glands. Small aggregations of lymphoid tissue may be present in the submucosa, specially near the lower end. Some plasma cells and macrophages are also present. The Muscularis Externa- The muscle layer consists of the usual circular and longitudinal layers. However, it is unusual in that the muscle fibres are paly striated and paly smooth. In the upper one-third (or so) of the oesophagus the muscle fibres are entirely of the striated variety, while in the lower onethird all the fibres are of the smooth variety. Both types of fibres are present in the middle onethird of the oesophagus. The Adventitia - The muscle layer of the oesophagus is surrounded by dense fibrous tissue that forms an adventitial coat for the oesophagus. The lowest pa of the oesophagus is intra-abdominal and has a covering of peritoneum. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no., 264,265.", "cop": 3, "opa": "Mucosa", "opb": "Submucosa", "opc": "Muscularis", "opd": "Adventitia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "311129b2-7073-46e1-81f7-3aaf37a5501b", "choice_type": "single"} {"question": "Most impoant mediator of chemotaxis is", "exp": "ref Robbins 7/e p56 ,9/e p77 C5a is a strong chemoattractant and is involved in the recruitment of inflammatory cells such as neutrophils, eosinophils, monocytes, and T lymphocytes, in activation of phagocytic cells and release of granule-based enzymes and generation of oxidants, all of which may contribute to innate immune functions or tissue ...", "cop": 2, "opa": "C3b", "opb": "C5a", "opc": "C5_7", "opd": "C2", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6be807d5-bb1e-4518-9291-cd515598a1d2", "choice_type": "single"} {"question": "Ideal bone for bone graft is", "exp": "The fibula is an ideal spare bone for a bone graft.Ref: Chaurasia; Volume 2; 6th edition; Page no: 29", "cop": 2, "opa": "Femur", "opb": "Fibula", "opc": "Radius", "opd": "Ulna", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "0a1feadc-1308-43c6-80e7-05afcf27defb", "choice_type": "single"} {"question": "Most common cause of bone malignancy", "exp": "Metastatic bone disease is the most commonest malignancy of bones and is much more than primary bone tumors Metastatic Bone Diseases(MBD) Cancer that begins in an organ, such as the lungs. breast, or prostate, and then spreads to bone is called metastatic bone disease (MBD). More than 1.2 million new cancer cases are diagnosed each year. Approximately 50% of these tumours can spread (metastasize) to the skeleton. With improved medical treatment of many cancers --especially breast. lung, and prostate -- patients are living longer. However, the primary cancers in more of these patients are spreading to bone. The tumours that result are called bone metastases. Organs involved in MBD * The most common cancers that arise from organs and spread to bone include: * Breast * Lung * Thyroid * Kidney * Prostate Pathophysiology of MBD : MBD causes pain in the area of spread. damages and weakens bone, and puts the patient at a greater risk for broken bones. It can make it hard to paicipate in daily activities. The biggest concern for patients with MBD is the general loss in quality of life. How much of an effect MBD has on a patient will vary and is associated with how much the cancer has spread. which bones are affected, and how severe the bone damage is. There are a range of treatment options, however. that can help patients manage pain and maintain their independence and activity levels. After the lung and the liver, the skeleton is the most common site of spread of cancers that begin in organs. Metastases to the lung and liver are often not detected until late in the course of disease because patients experience no symptoms. In contrast. bone metastases are generally painful when they occur. Cancer most commonly spreads to these sites in the skeleton: Spine Pelvis Ribs Skull Upper arm Symptoms Pain. The most common symptom of MBD is pain. Patients may have pain in the spine, pelvis, or extremities because the bone has been weakened by the tumour. Fractures. Weakened bones break more easily. A fracture from a minor injury is another possible sign of MBD. Anaemia. The most common sites of spread -- spine, pelvis, ribs, skull, upper arm, and long bones of the leg --correspond to areas of bone marrow that produce high levels of red blood cells, the cells responsible for carrying oxygen to tissues in the body. Anaemia (decreased red blood cell production) is a common blood abnormality in patients with MBD. A cancer patient who experiences any pain, especially in the back, legs, and arms, should notify his or her doctor immediately. Pain that occurs without activity (i.e., walking or lifting an object) is paicularly concerning. Refer Apleys 9th/e p 216", "cop": 1, "opa": "Secondaries", "opb": "Osteosarcoma", "opc": "Ewings sarcoma", "opd": "Osteoclastoma", "subject_name": "Anatomy", "topic_name": null, "id": "0cb57f43-c937-4572-a4ac-3f0479175ae5", "choice_type": "single"} {"question": "Frey's syndrome (gustatory sweating) is due to lesion of", "exp": "Auriculotemporal nerve carries parasympathetic secreto-motor fibres to parotid gland. After parotidectomy, sometimes there may be regeneration of secretomotor fibres in Auriculotemporal N This regeneration is misdirected into sweat glands. Thus, whenever the patient thinks of food/smells /chews food there would be stimulation of sweat glands & hyperaemia resulting in redness & sweating in front of ear on cheek. This clinical entity is called 'FREY SYNDROME'/AURICULOTEMPORAL SYNDROME/GUSTATORY SWEATING. Image showing Starch-iodine test:", "cop": 4, "opa": "Glossopharyngeal nerve", "opb": "Chorda tympani nerve", "opc": "Trigeminal nerve", "opd": "Auriculo-temporal nerve", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "485f90c8-104c-4347-8013-05b63ad7b306", "choice_type": "single"} {"question": "Nerve supply of tip of nose", "exp": "Nerve supply General sensory nerves derived from the branches of trigeminal nerve are distributed to whole of the lateral wall: Anterosuperior quadrant is supplied by the anterior ethmoidal nerve branch of ophthalmic nerve. Anteroinferior quadrant is suplied by the anterior superior alveolar nerve branch of infraorbital continuation of maxillary nerve. Posterosuperior quadrant is supplied by the lateral posterior superior nasal branches from the pterygopalatine ganglion. Posteroinferior quadrant is supplied by the anterior palatine branch from the pterygopalatine ganglion REF.BDC VOL.3,FIFTH EDITION", "cop": 1, "opa": "Ext nasal branch of ophthalmic division of", "opb": "Inferior orbital nerve", "opc": "Buccal br of mandibular nerve", "opd": "Orbital of maxillary n", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "0a977f95-6357-4e8b-9f6f-3001e5b705d7", "choice_type": "single"} {"question": "\"Dacryocystitis\" is interruption in drainage of", "exp": null, "cop": 3, "opa": "Submandibular gland", "opb": "Parotid gland", "opc": "Lacrimal gland", "opd": "Sublingual gland", "subject_name": "Anatomy", "topic_name": null, "id": "48e060b7-2a21-4fba-85c9-b23af6474744", "choice_type": "single"} {"question": "Formal thought disorder that is classical in mania is", "exp": "In flight of ideas, the individual stas at a point, shifts the topic , subsequent thoughts will have some association but they will not reach goal. This is classical of MANIA In loosening of association, patient comes with random thoughts that is not connected to each other and the goal is not reached. This is classical of schizophrenia they will introduce new words that are not present in one's dictionary , seen in SCHIZOPHRENIA In circumstantial speech individual stas about a topic, adds minute irrelevant details , beats around the bush and finally reaches the goal. This is seen in ORGANIC BRAIN CONDITIONS Ref. Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg No.194", "cop": 1, "opa": "flight of ideas", "opb": "loosening of assosiation", "opc": "neologism", "opd": "circumstantiality", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9b728749-350a-4a7e-a16d-de55fc99872f", "choice_type": "single"} {"question": "Anterior spinal artery is a branch of", "exp": null, "cop": 3, "opa": "Internal carotid artery", "opb": "Basilar artery", "opc": "Vertebral artery", "opd": "Labyrinthine artery", "subject_name": "Anatomy", "topic_name": null, "id": "c0bdddf8-c648-4d17-9972-ea2902839814", "choice_type": "single"} {"question": "Posterior communicating aery is branch of", "exp": "Posterior communicating aery arises close to the termination of internal carotid aery. Other branches of cerebral pa internal carotid aery are: Ophthalmic aery Anterior cerebral aery Middle cerebral aery Anterior choroidal aery Posterior cerebral aery is a branch of basilar aery. (Ref: Vishram Singh textbook of clinical neuroanatomy 2nd edition, pg- 176)", "cop": 1, "opa": "Internal carotid aery", "opb": "External carotid aery", "opc": "Middle cerebral aery", "opd": "Posterior cerebral aery", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "352d68f4-3e3b-43de-a122-77c83c603712", "choice_type": "single"} {"question": "Sacrococcygeal teratoma is a derivative of", "exp": "Sacrococcygeal teratoma: - Sometimes remnants of the primitive streak persist in the sacrococcygeal region. Then cluster of pluripotent cells proliferate & form tumor, known as sacrococcygeal teratomas Which commonly contain tissues derived from all three germ layers. Occurrence 1: 37,000 Most common tumor in a new born. Teratomas may also arise from abberent migration of primordial germ cells.", "cop": 1, "opa": "Primitive streak", "opb": "Hypoblast", "opc": "Ectoderm", "opd": "Cranial neuropore", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "6b62891f-eaf3-4933-b9e2-ed2d32f00107", "choice_type": "single"} {"question": "Liver is divided into", "exp": null, "cop": 1, "opa": "8 Couinaud segments", "opb": "7 Couinaud segments", "opc": "9 Couinaud segments", "opd": "10 Couinaud segments", "subject_name": "Anatomy", "topic_name": null, "id": "20c49653-2a4a-4fa4-899b-bb8c2ac09edf", "choice_type": "single"} {"question": "Coracoid process is an example for", "exp": "-This kind of epiphysis is a pa of the bone which exist as a separate bone in lower animals;but in humans it has fused with the main bone-Coracoid bone is a separate bone in aies", "cop": 3, "opa": "Pressure epiphysis", "opb": "Traction epiphysis", "opc": "Atavistic epiphysis", "opd": "Aberrant epiphysis", "subject_name": "Anatomy", "topic_name": null, "id": "d32e7099-d4a8-4ebd-b584-d2048c542ca8", "choice_type": "single"} {"question": "Middle superior alveolar nerve is a branch of", "exp": "C i.e. Anterior nasal division of maxillary nerve", "cop": 3, "opa": "Mandibular division of trigeminal nerve", "opb": "Palatine division of maxillary nerve", "opc": "Anterior nasal division of maxillary nerve", "opd": "Interior alveolar nerve", "subject_name": "Anatomy", "topic_name": null, "id": "d15a4529-1173-4632-9cc2-ba1c59ce0926", "choice_type": "single"} {"question": "Initial investigation for obstructive jaundice is", "exp": "Obstructive jaundiceObstructive jaundice is a paicular type of jaundice and occurs when the essential flow of bile to the intestine is blocked and remains in the bloodstream.Causes of Obstructive jaundice Due to blocked bile ducts caused by gallstones, or tumors of the bile duct.Swelling of lymph glands, scar tissue (from previous infections or surgery), or a cyst, possibly of the pancreas.Clinical featuresDiagnosisTreatmentSymptoms of obstructive jaundice include yellowing of the skin and whites of the eyes; paler stools and darker urine; and intense itching. Other symptoms vary, depending on the underlying cause of the obstruction although you may also feel tired.Blood tests to examine the level of bilirubinUltrasound of the liver and bile ducts to find out the exact cause of the obstruction CT scans are also used to help examine what is causing the blockageSurgical resection ERCP or a procedure is known as Percutaneous Transhepatic Cholangiography (PTC) with percutaneous biliary drainage(Refer: Sabiston's Textbook of Surgery, 19th edition, pg no: 1535-1544)", "cop": 1, "opa": "USG", "opb": "CT scan", "opc": "ERCP", "opd": "MRI", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "499c0f00-9d08-4185-9e73-1bea938670df", "choice_type": "single"} {"question": "A widely used the drug that suppresses cellular immunity,inhibits prostaglandin and leukotriene synthesis and increases the catabolism of IgG antibody is", "exp": "Ref-KDT 6/e p828,838 Glucocoicoids are powerful immunosuppresants. These inhibit both cellular and humoral immunity by: Decreasing the recruitment of immune cells Catabolism of immunoglobulins. Inhibiting the enzyme phospholipase A, resulting in decreased production of PGs,LTs and TXs", "cop": 2, "opa": "Cyclophosphamide", "opb": "Predisone", "opc": "Cyclosporine", "opd": "Infliximab", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "3f0cba17-53f5-4e38-af31-3730f421129a", "choice_type": "single"} {"question": "The narrowest pa of the ureter is at the", "exp": "Ureterovesical junction is the anatomical position where the ureters join the urinary bladder. This is the narrowest of the ureter. Ureters are surrounded by the valves called as ureterovesical valve which will prevent the vesicoureteral reflux. Ref - urologyhealth.org", "cop": 4, "opa": "Uretero - pelvic junction", "opb": "Illiac vessel crossing", "opc": "Pelvic uterer", "opd": "Uretero - vesical junction", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9cdea0f6-88b2-4545-b7ce-db9199c1d5a9", "choice_type": "single"} {"question": "Sensory supply for skin over angle of jaw is", "exp": "Cervial plexus supplies Skin over the angle of the jaw and over the parotid gland. Lower margin of the lower jaw", "cop": 3, "opa": "Opthalmic nerve", "opb": "Mandibular nerve", "opc": "Cervical plexus", "opd": "Maxillary nerve", "subject_name": "Anatomy", "topic_name": null, "id": "3810ff6e-9750-4596-b3e2-27815b024b43", "choice_type": "single"} {"question": "The most common congenital anomaly of the pancreas", "exp": "Pancreas divisum is the most common clinically significant congenital pancreatic anomaly, with an incidence 3% to 10% in autopsy series.", "cop": 1, "opa": "Pancreatic divisum", "opb": "Pancreatic cysts", "opc": "Ectopic pancreas", "opd": "Inversion of pancreatic ducts", "subject_name": "Anatomy", "topic_name": null, "id": "93028c12-c6b0-4b2f-b81e-6f59bfe8de8a", "choice_type": "single"} {"question": "Ligamentum teres develops from", "exp": "Umbilical vein \"In anatomy, the round ligament of liver (AKA: ligamentum teres - or more specifically ligamentum teres hepatis as the human body has three round ligaments in total) is a degenerative string of tissue that exists in the free edge of the falciform ligament of the liver. The round ligamentrepresents the remnant of the fetal left umbilical vein\"", "cop": 2, "opa": "Umbilical aery", "opb": "Umbilical vein", "opc": "Ductus venosus", "opd": "Poal radicles", "subject_name": "Anatomy", "topic_name": null, "id": "94326a65-d3e6-400a-8214-2afc769bdca7", "choice_type": "single"} {"question": "Factor present in final common terminal complement pathway", "exp": "Ref Harrison 17/e p2030 _2032 C5a is a protein fragment released from cleavage of complement component C5 by protease C5-convease into C5a and C5b fragments. C5b is impoant in late events of the complement cascade, an orderly series of reactions which coordinates several basic defense mechanisms, including formation of the Membrane Attack Complex (MAC), one of the most basic weapons of the innate immune system, formed as an automatic response to intrusions from foreign paicles and microbial invaders. It essentially pokes microscopic pinholes in these foreign objects, causing loss of water and sometimes death. C5a, the other cleavage product of C5, acts as a highly inflammatory peptide, encouraging complement activation, formation of the MAC, attraction of innate immune cells, and histamine release involved in allergic responses", "cop": 3, "opa": "C4", "opb": "C3", "opc": "C5", "opd": "Protein B", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dae1fd4c-a33e-4ba3-8924-b229ee3a135d", "choice_type": "single"} {"question": "Apical lung tumor causes", "exp": "Apical lung cancer/ Pancoast tumor causes - 2deg neuron injury (Preganglionic sympathetic fibres) I/L horner syndrome (Cervical sympathetic chain and ganglion involved) Loss of sweating on same side of face 1deg sympathetic neuron injury occurs in Wallenberg syndrome 2deg sympathetic neuron (preganglionic fibers) injury occurs in Apical lung cancer 3deg sympathetic neuron (postganglionic fibers) injury occurs in Internal carotid aery disection", "cop": 4, "opa": "C/L horner syndrome", "opb": "Post ganglionic fibres involved", "opc": "1deg neuron injury", "opd": "Loss of sweating on same side of face", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 3", "id": "4e243378-60a0-4085-94d9-e1a7b4b97259", "choice_type": "single"} {"question": "Epidural space lies between", "exp": ".", "cop": 3, "opa": "Pia and arachnoid", "opb": "Dura and arachnoid", "opc": "Dura and veebral column", "opd": "d) Pia mater and grey mater", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "2cfa365f-d369-4488-aa0e-531043910aa5", "choice_type": "single"} {"question": "Biceps Femoris, a hamstring muscle causes", "exp": "Hamstring Muscles( Biceps femoris long head, semitendinous, semimembranous, and adductor magnus) causes flexion at knee joint and Extension at Hip Joint. Hip flexion and knee Extension by quadriceps femoris muscle Hip and knee Flexion by saorious", "cop": 4, "opa": "Hip flexion and knee Extension", "opb": "Hip and knee Flexion", "opc": "Hip and knee Extension", "opd": "Hip extension and Knee Flexion", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "3b25bcb7-4465-4541-b291-968c27ed8a81", "choice_type": "single"} {"question": "Punishment for adultery is", "exp": "Man who commits the offence of adultery shall be punished with imprisonment up to 5 years or with fine or both. Ref: FORENSIC MEDICINE AND TOXICOLOGY DR PC IGNATIUS THIRD EDITION PAGE 308", "cop": 2, "opa": "2years", "opb": "5 years", "opc": "7 years", "opd": "10years", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "8c8425c8-d70f-4cfb-98db-80a6e01826c5", "choice_type": "single"} {"question": "AScoffs nodules are seen in", "exp": "Refer Harrison 17/2095 Robbins 9/e p558 Aschoff bodies are nodulesfound in the heas of individuals with rheumatic fever. They result from inflammation in the hea muscle and are characteristic of rheumatic hea disease The cardiac manifestations of rheumatic fever are in the form of focal inflammatoryinvolvement of the interstitial tissue in all 3 layers of the hea, a pathological change named pancarditis. The pathognomonicfeature of pancarditis in the case of rheumatic hea disease is the presence of Aschoff nodules or Aschoff bodies", "cop": 3, "opa": "Sub acute bacterial endocarditis", "opb": "Libman sacks endocarditis", "opc": "Rheumatic carditis", "opd": "Non bacterial thrombotuc endocarditis", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "38ef4d15-5723-4675-a91a-bee016bdd1eb", "choice_type": "single"} {"question": "The infratentorial dura is supplied by branches of the", "exp": "The tentorium cerebelli is a tent-shaped fold of dura mater, forming the roof of the posterior cranial fossa.It separates the cerebellum from the occipital lobes of the cerebrum and broadly divides the cranial cavity into supratentorial and infratentorial compaments. The infratentorial compament, in other words, is the posterior cranial fossa containing the hindbrain and the lower pa of the midbrain. The posterior cranial fossa is supplied chiefly by recurrent branches from first, second and third cervical spinal nerves and paly by meningeal branches of the ninth and tenth cranial nerves. Ref: BD Chaurasia; Volume 3; 6th edition; Page no: 92", "cop": 1, "opa": "Upper cervical spinal nerves and the vagus nerve", "opb": "Accessory and upper cervical nerve", "opc": "Only upper cervical nerves", "opd": "Only vagus nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "22fb5177-95b8-4a83-a4d9-9a0482f9e3cc", "choice_type": "single"} {"question": "The minor surfactant in lung is", "exp": "Phosphotidyl choline is major surfactant Sphyngomyelin is minor surfactant", "cop": 4, "opa": "Stearic acid", "opb": "Palmatic acid", "opc": "Phosphotidyl choline", "opd": "Sphyngomyelin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7c4b8911-c870-4d63-9e08-da758d5e126d", "choice_type": "single"} {"question": "Muscle involved in the rotation and protrusion of the mandible", "exp": null, "cop": 2, "opa": "Masseter", "opb": "Medial pterygoid", "opc": "Temporalis", "opd": "Digastric", "subject_name": "Anatomy", "topic_name": null, "id": "a643f131-65d3-4213-9063-0693bdb22fdd", "choice_type": "single"} {"question": "C cells are present in", "exp": "Cells of the ultimobranchial body give rise to the parafollicular or C cells of the thyroid gland. These cells secrete calcitonin, a hormone involved in regulation of the calcium level in the blood.Reference: Krishna Garg Histology; 5th edition; Page no: 230; 232", "cop": 1, "opa": "Thyroid gland", "opb": "Parathyroid gland", "opc": "Pituitary gland", "opd": "Thymus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "baf6b4c2-4eb3-4867-99dc-56ca352ad6cb", "choice_type": "single"} {"question": "NOT a content of Rectus sheath among the following is", "exp": "Thorcoabdominal nerves (T7 - T11) and Subcostal nerve ( T12) are the nerves of Rectus sheath. T6 is not the content of Rectus sheath", "cop": 4, "opa": "Pyramidalis", "opb": "Superior epigastric artery", "opc": "T12", "opd": "T6", "subject_name": "Anatomy", "topic_name": null, "id": "f0c6b2a7-3f1f-41ef-8d5c-9ffe67f76416", "choice_type": "single"} {"question": "Not under flexor retinaculum", "exp": "Structures deep to flexor retinaculum1) Lateral compament : Flexor carpi radialis tendon with its synol sheath lodged in the groove on the palmar surface of trapezium.2 Medial compament : (carpal tunnel proper).Structures superficially to flexor retinaculum 1) Palmaris longus tendon continuous with apex of palmar aponeurosis.2) Palmar cutaneous branch of median nerve.3) Palmar cutaneous branch of ulnar nerve.4) Ulnar nerve.5) Ulnar vessels protected superficially by volar carpal ligament (superficial pa of the flexor retinaculum).", "cop": 2, "opa": "Median nerve", "opb": "Ulnar nerve", "opc": "FDS", "opd": "FPL", "subject_name": "Anatomy", "topic_name": null, "id": "502d8d4b-bf45-4b13-9836-058caeff3e6f", "choice_type": "single"} {"question": "In agranuloma , epthiloid cells and giant cells are derived from", "exp": "ref Robbins 9/e p97 All granulomas, regardless of cause, may contain additional cells and matrix. These include lymphocytes, neutrophils, eosinophils, multinucleated giant cells, fibroblasts and collagen (fibrosis). The additional cells are sometimes a clue to the cause of thegranuloma. Macrophage and monocytes are also present", "cop": 2, "opa": "T lymphocytes", "opb": "Monocytes marcophages", "opc": "B lymphocytes", "opd": "Mast cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0f782df9-505f-41ca-b784-6b1407614eef", "choice_type": "single"} {"question": "Total bones in the skull are", "exp": "The skull consists of the 22 bonesCalvaria or brain case Facial skeleton Unpaired1.Frontal2.Occipital3.Sphenoid4.EthmoidUnpaired1.Mandible2.VomerPaired1.Parietal2.TemporalPaired1.Maxilla 2.Zygomatic 3.Nasal 4.Lacrimal 5.Palatine 6.Inferior nasal conchaReference: Chaurasia; 6th edition; Chapter 1; Osteology of head and neck", "cop": 2, "opa": "18", "opb": "22", "opc": "28", "opd": "32", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e9e65f90-949e-4b16-aa85-2876be9004dd", "choice_type": "single"} {"question": "Paradoxical splitting of second hea sound Heard in", "exp": "Ref Harrison 19 th ed pg 1447 Reversed or paradoxical splitting refers to a pathologic delay in aoic valve closure, such as that which occurs in patients with left bundle branch block, right ventricular pac- ing, severe AS, HOCM, and acute myocardial ischemia. With reversed or paradoxical splitting, the individual components of S2 are audible at end expiration, and their interval narrows with inspiration, the oppo- site of what would be expected under normal physiologic conditions.", "cop": 4, "opa": "RBBB", "opb": "ASD", "opc": "VSD", "opd": "LBBB", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7c831812-8b4e-46af-a796-62c9bbb513a4", "choice_type": "single"} {"question": "Jansen disease is", "exp": ".", "cop": 1, "opa": "Defect of PTH receptor", "opb": "Defect of GH receptor", "opc": "Defect of ADH receptor", "opd": "Defect of Thyroid receptor", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "8dbbd6b7-1470-4b39-9d38-72d893202ee1", "choice_type": "single"} {"question": "The neuroleptic malignant syndrome is characterized by", "exp": "Ref: Kaplan and Sadock&;s Synopsis of Psychiatry, 10th edition, pg no: 995Features of the Neuroleptic malignant syndrome:Increased body temperature >38degC (>100.4degF), orConfused or altered consciousnessDiaphoresis \"sweat shock\"Rigid musclesAutonomic imbalanceLabile hypeension Metabolic acidosis", "cop": 2, "opa": "Bradycardia", "opb": "Labile hypeension", "opc": "Hypotonia", "opd": "Hypothermia", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "9626c8c3-0599-467f-a27c-f1e9ce793efb", "choice_type": "single"} {"question": "Cilioretinal A is a branch of", "exp": "The posterior ciliary aery (PCA) circulation is the main source of blood supply to the optic nerve head (ONH), and it also supplies the choroid up to the equator, the retinal pigment epithelium (RPE), the outer 130 mm of retina (and, when a cilioretinal aery is present, the entire thickness of the retina in that region), and the medial and lateral segments of the ciliary body and iris. That makes the PCA circulation the most impoant pa of the ocular and ONH circulation. Therefore, disturbances in the PCA circulation can result in a variety of ocular and ONH vascular disorders, causing varying degrees of visual loss. I have investigated various aspects of the PCA circulation in health and disease by anatomic, experimental, and clinical studies since 1955. The objective of this lecture is essentially to summarize the main findings of those studies. It is beyond its scope to review the extensive literature on the subject that has accumulated over recent years. Ref - BD chaurasia 6e vol3 pg 212", "cop": 4, "opa": "Anterior ciliary aery", "opb": "Long posterior ciliary aery", "opc": "Cerebral retinal Aery", "opd": "Choroidal aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b27d17d0-aa85-4baf-8bd4-65dc9270a86e", "choice_type": "single"} {"question": "Axillary nerve supplies", "exp": "Posterior division of axillary nerve supplies the posterior pa of deltoid muscle and teres minor. Teres minor is one of the muscle in rotator cuff muscles. B D Chaurasia 7th edition Page no : 180", "cop": 2, "opa": "Supraspinatus", "opb": "Teres minor", "opc": "Teres major", "opd": "Infraspinatus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a8789c13-4c7f-4657-be6e-30faa4b96d33", "choice_type": "single"} {"question": "Hirsprung disease is due to", "exp": "C i.e. Failure of migration of neural crest cells from cranial to caudal direction", "cop": 3, "opa": "Loss of anterior longitudinal cells", "opb": "Loss of ganglionic cell in paraveebral sympathetic chain", "opc": "Failure of migration of neural crest.cell from cranial tocaudal direction", "opd": "Idiosyncratic", "subject_name": "Anatomy", "topic_name": null, "id": "c6300c87-c907-4a76-8c83-b4cccb71ed21", "choice_type": "single"} {"question": "Ergot alkaloid commonly used to prevent postpaum haemorrhage is", "exp": "Methylergometrine (methergin) is administered during delivery of anterior to prevent postpaum hemorrhage Ref-KDT 6/e p322", "cop": 1, "opa": "methyp ergometrine", "opb": "ergotamine", "opc": "dihydroergotamine", "opd": "dihydroergotoxine", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "3a887063-50ed-40a3-a377-71d74f54a584", "choice_type": "single"} {"question": "Metrinidazole is least likely to be effective in the treatment of", "exp": "Ref-KDT 6/e p686 Metranidazole is not effective against pneumocyst infection. The DOC for this condition is cotrimoxazole", "cop": 1, "opa": "Hepatic amoebiasis", "opb": "Infection caused by bacteroides fragilis", "opc": "Pseudomembranous colitis", "opd": "Pneumocystosis", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "bfd34a13-911f-43c3-a863-a40c44ad4857", "choice_type": "single"} {"question": "Centrum of veebra is formed from", "exp": "In the veebrate spinal column, each veebra is an irregular bone with... The upper and lower surfaces of the centrum are flattened and rough in order to give attachment to the interveebral discs.BD CHAURASIA S HUMAN ANATOMY Vol1", "cop": 3, "opa": "Pre axial mesoderm", "opb": "Notochord", "opc": "Paraxial mesoderm", "opd": "Somatic mesoderm", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "394730a6-6ecc-4e70-a5b0-19a267c8d7cd", "choice_type": "single"} {"question": "High calcium intake can lead to", "exp": "Refer Robbins page no Milk alkali syndrome is due to excessive ingestion of calcium and absorbabke antacids such as milk or calcium carbonate .This is associated with the development of metastatic Calcification", "cop": 3, "opa": "Osteoporosis", "opb": "Osteopotrosis", "opc": "Milk alkali syndrome", "opd": "Renal failure", "subject_name": "Anatomy", "topic_name": "Endocrinology", "id": "1f8d01ad-bfc0-40f5-856b-91a4bdcf719e", "choice_type": "single"} {"question": "Major flexor of hip joint", "exp": "The hip flexors Vesi are (in descending order of impoance to the action of flexing the hip joint): Collectively known as the iliopsoas or inner hip muscles: Psoas major Iliacus muscle Anterior compament of thigh Rectus femoris (pa of the quadriceps muscle group) Saorius One of the gluteal muscles: Tensor fasciae latae Medial compament of thigh Pectineus Adductor longus Adductor The psoas major is a long fusiform muscle located on the side of the lumbar region of the veebral column and brim of the lesser pelvis. It joins the iliacus muscle to form the iliopsoas. Ref - BDC 6th edition vol2 ; pg 139", "cop": 1, "opa": "Psoas major", "opb": "Gluteus maximus", "opc": "Tensor fasciae latae", "opd": "Hamstring", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "3fb7fe3b-5161-4517-8974-a351c9f6879a", "choice_type": "single"} {"question": "In child's criteria paial encephalopathy, bilirubin 2.5mg/dl, albumin 3gm/dl, prothrombin time 5min and controlled ascites indicates", "exp": "Refer previous question child-Turcotte point score table Ref: Sabiston 20th edition Pgno : 1436", "cop": 2, "opa": "Grade A", "opb": "Grade B", "opc": "Grade C", "opd": "More information needed", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ce1329da-d35e-4c2f-85ec-bf26432f925d", "choice_type": "single"} {"question": "Intraocular muscle supplied by Edinger Westphal nucleus is", "exp": "All pas of the muscle are supplied by parasympathetic nerves. The pathway involves the Edinger-Westphal nucleus, oculomotor nerve, and the ciliary ganglion. The nerve to inferior oblique gives a branch for the ciliary ganglion. This branch brings the fibres of Edinger-Westphal nucleus (GVE) to the ganglion for relay. The postganglionic fibres end up in supplying the ciliaris for enhancing the anterior curvature of the lens and the sphincter pupillae for narrowing the size of the pupil. Both these are intraocular muscles required for accommodation. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition", "cop": 2, "opa": "Superior oblique", "opb": "Ciliary muscle", "opc": "Lateral rectus", "opd": "Medial rectus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "e921c35f-c15f-4f14-8b4f-193a8514cd51", "choice_type": "single"} {"question": "If circumflex aery gives the posterior interventricular branch, this circulation is described as aEUR'", "exp": "Left dominance Dominance of the coronary aerial system depends on which aery gives rise to the posterior interventricular branch (posterior descending aery). This branch supplies adjacent areas of both ventricles and posterior third of the IV septum.Right dominance: In this more conzmon type the posterior interventricular aery is a brute of . coronary aery. Seen in 67 to 90% of the population (67% according to Moore's 5/e and 90% according to Snell's 6/e and BDC 4/e, and some middle values on internet)Left dominance: The circumflex aery, the continuation of left coronary provides the post. IV branch (Seen in 10 to 15%)Codominance/balanced: Branches of both right and left coronary aery run in or near the sulcus.Note that the term 'Right dominance' is misleading, since the left aery almost always supplies a greater volume of tissue.", "cop": 2, "opa": "Right dominance", "opb": "Left dominance", "opc": "Codominance", "opd": "Undetermined", "subject_name": "Anatomy", "topic_name": null, "id": "0e9b5e3f-9ab5-4316-b9c2-641146a6254a", "choice_type": "single"} {"question": "A \"Potential Anastomosis\" seen in", "exp": "Aerial anastomosis is the communication between the aeries, or branches of aeries. It may be actual or potential. Actual Aerial Anastomosis: In actual aerial anastomosis the aeries meet end to end. For example, palmar arches, plantar arch, circle of Willis, intestinal arcades, labial branches of facial aeries. Potential Aerial Anastomosis: In potential aerial anastomosis the communication takes place between the terminal aerioles. Such communications can dilate only gradually for collateral circulation. Therefore on sudden occlusion of a main aery, the anastomosis may fail to compensate the loss. The examples are seen in the coronary aeries and the coical branches of cerebral aeries. Ref - Medscape.com", "cop": 3, "opa": "Labial branch of facial aery", "opb": "Intercostal aery", "opc": "Coronary aery", "opd": "Aerial arcades of mesentery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "29c000e9-8b6e-4dd4-96d1-fa6256a566c8", "choice_type": "single"} {"question": "Choledochal cyst in intrahepatic biliary tree", "exp": "Todani Modification of Alonso-Lej classification Type I - Dilation of extrahepatic biliary tree Type Ia- cystic dilation Type Ib - focal segmental dilation Type Ic- fusiform dilation Type II - Diveicular dilation of extrahepatic biliary tree Type III - Cystic dilation of intra duodenal poion of common bile ducts (choledochocele) Type IVA- Dilation of the extrahepatic and intrahepatic biliary tree Type IVB- Dilation of multiple secretion of extrahepatic bile ducts Type V - Dilation confined to intrahepatic bile ducts (caroli's disease) Type VI - Cystic dilation of cystic duct (not included in Todani's modification) Ref: Sabiston 20th edition Pgno :1510-1511", "cop": 3, "opa": "I", "opb": "II", "opc": "IVa", "opd": "IVb", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e2ffc187-b0d1-432c-abe5-2e6bf87c51b2", "choice_type": "single"} {"question": "Contraindication of TIPSS is", "exp": "Contraindications of TIPSS Absolute Right sided hea failure Polycystic liver disease Pulmonary hypeension Hepatopulmonary syndrome Relative Poal vein thrombosis Hypervascular liver tumors Encephalopathy Ref: Sabiston 20th edition Pgno :1439", "cop": 1, "opa": "HPS", "opb": "HRS", "opc": "VOD", "opd": "BCS", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b0c751c6-e318-48df-b683-5ae5f3218b43", "choice_type": "single"} {"question": "Muscles of the anterior compament of the leg are innervated primarily by", "exp": "In the leg, the deep peroneal nerve supplies muscular branches to the Tibialis anterior, Extensor digitorum longus, Fibularis (Peroneus) teius, and Extensor hallucis longus, and an aicular branch to the ankle-joint.", "cop": 1, "opa": "Deep peroneal nerve", "opb": "Superficial peroneal nerve", "opc": "Sural nerve", "opd": "Saphenous", "subject_name": "Anatomy", "topic_name": null, "id": "595b47d2-c1bb-4323-9179-979787a3a4ba", "choice_type": "single"} {"question": "Foramen scarpa is another name of", "exp": null, "cop": 2, "opa": "Mental foramen.", "opb": "Incisive foramen", "opc": "Infra orbital foramen.", "opd": "Supraorbital foramen.", "subject_name": "Anatomy", "topic_name": null, "id": "917afbe2-1dbf-40b3-bf1a-dbac3e0f4fdf", "choice_type": "single"} {"question": "ANCA is most specific and sensitive marker for", "exp": "Robbins 9/e p 910-911 merulonephritis and cases of crescentic glomerulone- phritis that occur as a component of systemic vasculitis, and the similar pathologic features in either setting, have led to the idea that these disorders are pathogeneti- cally related. According to this concept, all cases of crescentic glomerulonephritis of the pauci-immune type are manifestations of small-vessel vasculitis or polyangiitis, which is limited to glomerular and perhaps peritubular capillaries in cases of idiopathic crescentic glomerulonephritis. Since these entities are viewed", "cop": 1, "opa": "Idiopathic cresteric glomerlunephritis", "opb": "Post streptococcal Glomerulonephritis", "opc": "Membranoproliferative glomerulonephritis", "opd": "Focal segmental Glomerulunephritis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f2137ab5-4a03-45d0-9f3f-cef130aaa2c5", "choice_type": "single"} {"question": "Treatment of choice for cyanide poisoning is", "exp": "Refer kDT 6/e p527 Administer a cyanide antidote if the diagnosis of cyanide toxicity is strongly suspected, without waiting for laboratory confirmation. Available antidotes are hydroxocobalamin (Cyanokit) and sodium thiosulfate and sodium nitrite (Nithiodote). Both are given intravenously. Patients who present with more than minimal symptoms that resolve without treatment should be admitted for observation and suppoive care. In patients with acute poisoning from hydrogen cyanide (HCN) gas or soluble salts, the principal acute care concerns are hemodynamic instability and cerebral edema. The continuous cardiac monitoring, respiratory and cardiovascular suppo, and frequent neurologic evaluation these patients require is generally best provided in an intensive care unit.", "cop": 4, "opa": "NaHCo3", "opb": "KMnO4", "opc": "Nacl", "opd": "Sodium nitrate followed by thiosulphate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cc344fb9-0565-4a04-af37-571d8fd0ddec", "choice_type": "single"} {"question": "Middle cerebellar peduncle transmits fibres of", "exp": "A. i.e. Pontocerebellar pathway", "cop": 1, "opa": "Ponto cerebellar pathway", "opb": "Tectospinal pathway", "opc": "Spinocerebellar pathway", "opd": "Olivo cerebellar pathway", "subject_name": "Anatomy", "topic_name": null, "id": "e31d24f7-a3dd-4dc2-a296-db8ecd38256c", "choice_type": "single"} {"question": "Kayser Fleischer ring is seen in", "exp": "Refer Robbins page no 850 Toxic injury to the brain primarily affects the basal ganglia, paicularly the putamen, which shows atrophy and even cavita- tion. Nearly all patients with neurologic involvement develop eye lesions called Kayser-Fleischer rings, green to brown depos- its of copper in Descemet membrane in the limbus of the cornea.", "cop": 1, "opa": "Wilson's disease", "opb": "Alpha 1antitrypsin deficiency", "opc": "Hemochromatosis", "opd": "Primary biliary cirrhosis", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "933371ce-8ca3-4464-aa42-648a104a9a40", "choice_type": "single"} {"question": "Largest lymphoid organ is", "exp": "(B) Spleen [BDC II4-279# Largest lymphatic organ in the human body is the spleen.> Primary function of the spleen is to purify the blood and store blood cells.> It helps the immune system identify and combat foreign antibodies.> Spleen consists of white pulp and red pulp.> White pulp generates blood cells and synthesizes antibodies, and the red pulp removes old blood cells and filters the blood.", "cop": 2, "opa": "Liver", "opb": "Spleen", "opc": "Thymus", "opd": "Kidney", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "e91e7fd1-be6f-4a7d-b9b8-378944a3e01d", "choice_type": "single"} {"question": "Balthazar scoring system is used for", "exp": "Computed Tomography severity index(CTSI) for acute pancreatitis CTSI= Balthazar grade score + necrosis score Highest attainable score =10 CTSI score 0-3: Moality 3%,Morbidity 8% 4-6: Moality 6%, Morbidity 35% 7-10: Moality 17%, Morbidity 92% Refer CTSI table Ref: Sabiston 20th edition Pgno :1527", "cop": 1, "opa": "Acute pancreatitis", "opb": "Acute appendicitis", "opc": "Acute cholecystitis", "opd": "Cholangitis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d70147a3-9095-4d15-83de-5d6a74f300b5", "choice_type": "single"} {"question": "Failure of descent of thyroid analage can be seen in the tongue", "exp": null, "cop": 3, "opa": "In anterior 2/3 of dorsal aspect", "opb": "In posterior 1/3 of dorsal aspect", "opc": "Near the base of tongue close to foramen caecum", "opd": "In anterior 2/3 of inferior surface", "subject_name": "Anatomy", "topic_name": null, "id": "10a11d66-f8c4-45aa-8b9a-ee0650101a8d", "choice_type": "single"} {"question": "Safety muscle of tongue is", "exp": null, "cop": 2, "opa": "Hyoglossus", "opb": "Genioglossus", "opc": "Palatoglossus", "opd": "Styloglossus", "subject_name": "Anatomy", "topic_name": null, "id": "58769b68-42c5-4c1f-90a8-772411ea8c38", "choice_type": "single"} {"question": "Deep injury of neck always involves", "exp": "Investing layer lies deep to the platysma and surrounds the neck like a collar. The surgeon has to stitch platysma muscle separately so that skin does not adhere to deeper neck muscles otherwise the skin will get an ugly scar. Ref BDC volume 3;sixth edition pg 81", "cop": 1, "opa": "Platysma", "opb": "Trapezius", "opc": "Sternocleidomastoid", "opd": "Longus colli", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b6f0b264-14fe-4360-8e5f-7ee786a3b7c5", "choice_type": "single"} {"question": "Hanging cast is used in", "exp": "Refer Maheshwari 6th/e 94 Most of the closed fractures can be treated by hanging cast from shoulder to wrist with the elbow flexed to 90 degree Other methods of conservative Treatment areU-slab,chest arm bandage and functional castbrace", "cop": 4, "opa": "Femur", "opb": "Radius", "opc": "Tibia", "opd": "Humerus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "33734b3f-2817-4407-8888-8014d50e97c4", "choice_type": "single"} {"question": "Auxillary ohotopic liver transplant is indicated for", "exp": "Indication of Auxillary Paial Ohotopic Liver Transplantation (APOLT) Reversible fulminant hepatic failure Small for size grafts Non- Cirrhotic metabolic liver disease ABO incompatibility AOPLT In fulminant hepatic failure, APOLT provides temporary suppo until the native liver recovers and then immunosuppression can be withdrawn APOLT can compensate for enzyme deficiency in non-cirrhotic metabolic liver disease Transplants of ABO incompatible grafts are often unavoidable due to limited number of potential donor candidates. A high incidence of early graft failure with a high rate of biliary and vascular complication in ABO incompatible liver transplantation is repoed. The remnant liver could sustain a patients life if the anticipated graft failure occurred in an ABO incompatible case In small for graft size, the remnant liver is expected to suppo the function of implanted graft during the early post op period. The graft liver expands its function in propoion to volume growth. After the graft liver has grown sufficiently, it can be expected to meet the hepatic functional demands of the reciepient Ref: Blumga 5th edition Pg no : 1689-1693", "cop": 1, "opa": "Metabolic liver disease", "opb": "As a standby procedure until finding a suitable donor", "opc": "Drug induced hepatic failure", "opd": "Acute fulminant liver failure for any cause", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3354a8f5-cdc4-4928-a647-ed49fc098543", "choice_type": "single"} {"question": "Biceps brachii does not arise from", "exp": "BICEPS BRACHII:-Origin: Two heads-Long head-supraglenoid tubercle of scapula and glenoid labrum.Sho head-coracoid process of scapula.Inseion:-posterior rough pa of radial tuberosity Nerve supply:-musculocutaneous nerve.Action: supination of forearm when elbow is flexed.Flexion of forearm when elbow is extended.Biceps reflex:-Tapping tendon of biceps brachii by reflex hammer with forearm pronated and paially extended at elbow. Normal reflex confirms the integrity of musculocutaneous nerve and C5 and C6 spinal segments.{Reference: Vishram Singh, pg no.105}", "cop": 4, "opa": "Supraglenoid tubercle", "opb": "Glenoid labrum", "opc": "Coracoid process", "opd": "Front of humerus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "53175c78-4c50-4fdd-81d3-58b54da6e591", "choice_type": "single"} {"question": "The layer responsible for strength of an intestinal anastomosis is", "exp": "Mechanical propeiesThe mechanical propeies of the intact intestine in axial and transversal directions were different. The mechanical strength of the intact intestinal wall was conditioned by the submucosa and muscularis, while the serosa and mucosa showed no significant strength. Comparison of axial specimens&; mechanical propeies of the intact intestinal wall and intestinal wall with all layers sutured through determined that only the submucosa supplies mechanical strength to the anastomosis.Other layers contribute no significant force to anastomotic strength. The strength applied to the thread during knot tying does not change the paicipation of the intestinal layers in supplying suture-holding capacity for 8 and 12 mm stitch depth. (Refer:", "cop": 2, "opa": "Mucosa", "opb": "Submucosa", "opc": "Muscularis propria", "opd": "Serosa", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7f8124d9-a169-4cec-9201-be0c1cc4f49f", "choice_type": "single"} {"question": "Testis lies in deep inguinal ring upto", "exp": "Descent of testis The testes develop in relation to the developing mesonephros, at the level of segments T10 to T12. Subsequently, they descend to reach the scrotum. Each testis begins to descend during the second month of intrauterine life. It reaches the iliac fossa by the 3rd month Rests at the deep inguinal ring from the 4th to the 6th month, Traverses the inguinal canal during the 7th month, Reaches the superficial inguinal ring by the 8th month and the bottom of the scrotum by the 9th month. An extension of peritoneal cavity called the processus vaginalis precedes the descent of testis into the scrotum, into which the testis invaginates. The processus vaginalis closes above the testis. Descent does not occur after one year of age. Ref - BDC 6th edition vol2 pg 227", "cop": 3, "opa": "4th month", "opb": "5th month", "opc": "7th month", "opd": "9th month", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "9854babf-873c-42f1-b39b-0639afdcae21", "choice_type": "single"} {"question": "Most common cranial nerve palsy in basilar skull\nfracture", "exp": null, "cop": 3, "opa": "Optic nerve", "opb": "Olfactory nerve", "opc": "Facial nerve", "opd": "Auditory nerve", "subject_name": "Anatomy", "topic_name": null, "id": "b9d5fd73-8752-4ba7-9c95-34ab3c13f8f5", "choice_type": "single"} {"question": "Hemorrhagic infraction is seen in", "exp": "Ref Harrison 18/e p162,9/e p123 A hemorrhagic infarct (HI) can be defined as an ischemic infarct in which an area of bleeding exists within necrosing cerebral tissue. This definition includes smallhemorrhages confined to minor ischemic areas in grey matter as well as much larger lesions involving coical and deep hemispheric regions. Cerebral venous sinus thrombosis (CVST) is the presence of thrombosis in the dural vein, which occurs when a blood clot forms in the brain's venous sinus that prevents blood from draining out of the brain . Patients with venous sinus thrombosis have a variety of symptoms . Venous hemorrhagic infarction (VHI) is presented as a severe form of clinical symptom and a poor prognostic factor of CVST .", "cop": 1, "opa": "Venous thrombosis", "opb": "Thrombosis", "opc": "Septicaemia", "opd": "Embolism", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ee097f0-5ab7-4dd5-ba4b-c08732c7424b", "choice_type": "single"} {"question": "Griesofulvin is not useful in one of the following", "exp": "Refer CMDT 2010/110 *griesofulvin is used for dermatophytoses including Tinea capitis, Tinea cruris, Tinea pedis, Tinea ungunum and Tinea corporis *Tinea versicolor is caused by yeast Malassezia furfur .it is treated by selenium sulfide AMD ketaconazole shampoo", "cop": 3, "opa": "Tinea capitis", "opb": "Tinea Cruris", "opc": "Tinea versicolor", "opd": "Tinea pedis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fc3110ba-dbf1-4a4b-beaa-9abad5cb3a03", "choice_type": "single"} {"question": "Elimination of alcohol follows", "exp": "Elimination of alcohol from blood is always linear with time, i.e., zero order kinetics. Ref-KDT 6/e p38", "cop": 1, "opa": "Zero order kinetics", "opb": "First order kinetics", "opc": "Second order kinetics", "opd": "Third Order kinetics", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "993bb4a6-a4ec-4ae4-afab-837941523abd", "choice_type": "single"} {"question": "a patient was brought to psychiatry casuality with contraction of the neck , the patient told that it was painul. this symptom staed after the injection given at the psychiatry hospital for his psychosis. the type of side effect caused by the drug is", "exp": "Acute dystonia * <48 hours of staing antipsychotics * M.C in======Younger black males * If a patient develops dystonia he is more prone for eps Patient considers this as an Allergic reaction , thereby may stop drugs Layryngeal dystonia is a Psychiatric emergency, should be treated with IV lorazepam TREATMENT * Diphenhydramine * Benztropine mesylate * Prophylactic anticholinergics helps Ref. Kaplonand sadock, synopsis of psychiatry, 11 th edition, page no. 925", "cop": 1, "opa": "dystonia", "opb": "neuroleptic malignant syndrome", "opc": "akathisa", "opd": "tardive dyskinesia", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "8602413e-fc50-497e-81dd-796bfd7972dc", "choice_type": "single"} {"question": "In ductus venous, the fetal blood from the placenta reaches to the liver through", "exp": "when there is an increase in placental circulation, to facilitate the rapid transpo of blood through the liver ,a large passage is formed between left umbilical vein and right hepato cardiac channel.This passage is called ductus venosus REFERENCE: TEXTBOOK OF CLINICAL EMBRYOLOGY... VISHRAM SINGH SECOND EDITION....PAGE NO:241", "cop": 4, "opa": "Poal vein", "opb": "Right umbilical vein", "opc": "Inferior vena cava", "opd": "Left umbilical vein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9a0193f1-1fb8-403c-bdd7-5cd57577f00b", "choice_type": "single"} {"question": "charecterstic of anorexia nervosa is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "overweight", "opb": "intense fear of becoming fat", "opc": "binge eating", "opd": "metabolic syndrome", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "f88d328c-51b9-4639-b97e-7702f78f37b5", "choice_type": "single"} {"question": "Three point bony relationship Of the elbow is disturbed", "exp": "Fracture lateral condyle of the humerus Three point bony relation ship of elbow Fracture of medial or lateral and condyke/epicondyle/intercanglylar area Fracture of olecranon Elbow dislocation Refer Kenneth A Evil 4th p 609", "cop": 2, "opa": "Supracondylar fracture of humerus", "opb": "Fracture lateral Condyleof humerus", "opc": "Monteggia fracture dislocation", "opd": "Fracture of proximal radius", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f2240f31-cf5f-4920-bcca-1fe0ed75f56b", "choice_type": "single"} {"question": "Most common benign tumor of liver is", "exp": "Most common benign tumor of the liver Mainly seen in women of 45 years Small capillary hemangiomas(no clinical significance), larger cavernous hemangioma Usually single and <5 cm in diameter, occur equally in right and left liver Giant hemangioma: lesion>5cm Pathology Microscopically: Endothelium-lines, blood filled spaces that are seperated by thin, fibrous septa Enlargement of hemangiomas are by ectasia rather than neoplasia Clinical features Most commonly asymptomatic and incidentally found on imaging studies Large compressive masses may cause vague upper abdominal symptoms Kasabach-Merritt syndrome; syndrome of thrombocytopenia and consumptive coagulapathy Rarely seen LFT's and tumor markers are normal Diagnosis Diagnosis is made radiologically CT and MRI are diagnostic if a typical peripheral nodular enhancement pattern is seen Percutaneous biopsy is potentially dangerous and inaccurate not recommended Treatment Observation for asymptomatic cases Enucleation with inflow control is TOC for symptomatic cases Ref : Sabiston 20th edition Pgno :1456-1457", "cop": 1, "opa": "Hemangioma", "opb": "Hepatic adenoma", "opc": "Hepatoma", "opd": "Hamaoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "2e572684-6f03-4cd6-9586-f6095af8f3b7", "choice_type": "single"} {"question": "Maximum unsaturated fatty acids are seen in", "exp": "FatsPUFASafflower oil75Sunflower seed oil65Soya bean oil62Margarine 50Groundnut oil31Palm oil10Butter 3Coconut oil2(Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 649)", "cop": 3, "opa": "Mustard oil", "opb": "Groundnut oil", "opc": "Safflower oil", "opd": "Coconut oil", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "e32006ed-15b7-47f2-b7b5-5d6a00bd9d41", "choice_type": "single"} {"question": "Regarding sexual differentiation of the fetus", "exp": "OptionB: SRY Gene located on Y chromosome encodes Testis Determining Factor which leads to the development of male genital organs Option C&D: Development of external genitalia is similar in males and females till the 6th week of IUL(Indifferent stage)....later develops in the direction of hormones. REFERENCE: TEXTBOOK OF CLINICAL EMBRYOLOGY... VISHRAM SINGH SECOND EDITION..PAGE NO:277", "cop": 1, "opa": "Gonadal development begins at 5th week of intrauterine life", "opb": "Y chromosome determines the differentiation of ovaries", "opc": "Female external genitalia development is completed by 10 weeks", "opd": "Male sexual differentiation occurs earlier than females", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e1176adb-60a7-47ed-b1c4-5214d1f25cef", "choice_type": "single"} {"question": "Amyloid is", "exp": "Ref Robbins 9/e p256 Amyloidosis is a condition associated with a number of inherited and inflammatory disorders in which extracel- lular deposits of fibrillar proteins are responsible for tissue damage and functional compromise. These abnormal fibrils are produced by the aggregation of misfolded pro- teins (which are soluble in their normal folded configura- tion) or protein fragments. The fibrillar deposits bind a wide variety of proteoglycans and glycosaminoglycans, including heparan sulfate and dermatan sulfate, and plasma proteins, notably serum amyloid P component (SAP). The presence of abundant charged sugar groups in these adsorbed proteins gives the deposits staining charac- teristics that were thought to resemble starch (amylose). Therefore, the deposits were called \"amyloid,\" a name that is firmly entrenched despite the realization that the depos- its are unrelated to starch.", "cop": 3, "opa": "Mucopolysaccharide", "opb": "Lipoprotein", "opc": "Glycoproteins", "opd": "Intermediate filament", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0d12039c-9637-4108-9e9f-0978d63fc44d", "choice_type": "single"} {"question": "Not a branch of posterior cord of Brachial plexus", "exp": "Long thoracic nerve arises from the nerve root of C5-C7 and it supplies serratus anterior muscle. The axillary nerve supplies the deltoid and teres minor muscles. The thoracodorsal nerve supplies the latissimus dorsi muscle. The radial nerve supplies 3 heads of triceps brachii and 12 muscles on the back of the forearm. Mnemonic Posterior cord - ULTRA U- upper subscapular nerve L-lower subscapular nerve T-thoracodorsal R-radial nerve A-axillary nerve B D Chaurasia 7th edition Page no: 58 Fig: 4.14,page no:55 BD chaurasia 6th edition.", "cop": 4, "opa": "Axillary nerve", "opb": "Thoracodorsal nerve", "opc": "Radial nerve", "opd": "Ulnar nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "7cb66b48-e4a6-4b99-bc0c-bd344af53583", "choice_type": "single"} {"question": "Most common site of ectopic pancreatic tissue", "exp": "Accessory pancreatic tissue found in stomach duodenum or mechel's diverticulam.", "cop": 1, "opa": "Stomach", "opb": "Jejunam", "opc": "Appendix", "opd": "Hilum of spleen", "subject_name": "Anatomy", "topic_name": null, "id": "173b8033-4e23-4972-8212-bf411fa3efa6", "choice_type": "single"} {"question": "Anterior neuropore closes at", "exp": "Clinical neuroanatomy; Vishram Singh; Pg no:7 Anterior/cranial neuropore closes at 24th day of intrauterine life if dont close Anencephaly", "cop": 2, "opa": "16 days", "opb": "24 days", "opc": "28 days", "opd": "8 days", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c2728986-6a48-4202-8470-163d35be4ce8", "choice_type": "single"} {"question": "Poosystemic shunt is not sent in", "exp": "At the liver, hepatic sinusoids& superior epigastric veins are forming poocaval anastomosis, at rectum superior rectal&middle, inferior rectal vein forms, at oesophagus between left gastric and azygos vein. Ref: Gray's 39e/p1026", "cop": 2, "opa": "Liverpool", "opb": "Spleen", "opc": "Anorectum", "opd": "Gastrointestinal Esophageal", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d32ba19b-6cf3-4bff-b2a2-6824813748fe", "choice_type": "single"} {"question": "Ferruginous bodies are seen in", "exp": "Inorganic paicles may become coated with iron protein complexes and ate called Ferruginous bodies A ferruginous body is a histopathologic finding in interstitial lung disease suggestive of significant asbestos exposure (asbestosis). Asbestos exposure is associated with occupations such as shipbuilding, roofing, plumbing, and constructio Refer robbins 9/e", "cop": 3, "opa": "Silicosis", "opb": "Byssinosis", "opc": "Asbestosis", "opd": "Bagassosis", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "a4599e3b-9746-4b5e-a4b2-3cfb05433323", "choice_type": "single"} {"question": "Neutrophil secretes", "exp": "ref Robbins 7/e p73 Cathepsin G also secreted by neutrophil", "cop": 2, "opa": "Superoxide dismutase", "opb": "Myeloperoxidase", "opc": "Lysosomal enzyme", "opd": "Catalase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ba335b4-c9d8-47c1-9ebe-c746989cb966", "choice_type": "single"} {"question": "Laryngeal prominence is formed by", "exp": "Thyroid cailage is V-shaped in cross-section.It consists of right and left laminae. each lamina is roughly quadrilateral.The laminae are placed obliquely relative to the midline,their posterior borders are far apa but the anterior borders approach each other at an angle that is about 90 degree in the male and about 120 degree in the female. The lower pas of the anterior borders of the right and left laminae fuse and form a median projection called the laryngeal prominence.", "cop": 4, "opa": "Cricoid cailage", "opb": "Hyoid bone", "opc": "Anterior margin of thyroid", "opd": "Angle of the thyroid cailage", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "01180949-e950-41a9-af0b-46647e262e81", "choice_type": "single"} {"question": "The nerve that emerges from the two superficial heads of lateral pterygoid muscle is", "exp": null, "cop": 1, "opa": "Buccal nerve", "opb": "Massetric nerve", "opc": "Nerve to pterygoid muscle", "opd": "Inferior alveolar nerve", "subject_name": "Anatomy", "topic_name": null, "id": "e9de453c-f159-4579-a58f-f2a84ca694df", "choice_type": "single"} {"question": "Anterior 2/3 of tongue develops from", "exp": "The anterior two-thirds: From two lingual swellings which arise from the first branchial arch. Therefore, it is supplied by lingual nerve of first arch and chorda tympani of second arch The posterior one-third: From cranial large pa of the hypobranchial eminence, that is from the third arch. Therefore, it is supplied by the glossopharyngeal nerve The posterior-most pa from the fouh arch. This is supplied by the vagus nerve Ref BDC volume 3,sixth edition pg 270", "cop": 1, "opa": "1st branchial arch", "opb": "2nd branchial arch", "opc": "3rd branchial arch", "opd": "4th branchial arch", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9bf044ee-c684-40de-a4cf-812cfc8cac74", "choice_type": "single"} {"question": "Length of male urethra is", "exp": "Length of male urethra is 20 cm long and female urethra is 4 cm long. Male urethra contains 3 pas- Prostatic urethra- 4 cm Membranous urethra-0.5-0.6 cm Spongy urethra -15 to 20 cm", "cop": 3, "opa": "10 cm", "opb": "15 cm", "opc": "20 cm", "opd": "30 cm", "subject_name": "Anatomy", "topic_name": "Pelvis and Perineum 3", "id": "e510993f-b188-4e25-b35b-63b35431e960", "choice_type": "single"} {"question": "Sacrotuberous ligament is pierced by", "exp": "Ans: A Perforating cutaneous nerveSacrotuberous ligament (STL) -Stabiliser of sacro-iliac joint.Connects bony pelvis to veebral column.Structure piercing STL - Perforating cutaneous nerve.Perforating cutaneous nerve:Cutaneous nerve that arises from the 52 and 53 nerve roots of the sacral plexus.Supplies lower medial pa of buttock.", "cop": 1, "opa": "Perforating cutaneous nerve", "opb": "Posterior femoral cutaneous", "opc": "Superior gluteal nerve", "opd": "Sciatic nerve", "subject_name": "Anatomy", "topic_name": null, "id": "e942c96f-33ee-4b46-9413-c9a7b58b04ac", "choice_type": "single"} {"question": "Deformity with decreased carrying angle is", "exp": "Refer Apleys 9th e p 372 Cubitus varus develops which is reduced carrying angle and Cubitus valgus is increased carrying angle", "cop": 1, "opa": "Cubitus varus", "opb": "Mannus varus", "opc": "Cubitus valgus", "opd": "Mannus valgus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8a9f1643-e566-4d39-9d2d-626821888c52", "choice_type": "single"} {"question": "Fibrous pericardium in supplied by", "exp": "Fibrous pericardium in supplied by phrenic Nerve. Visceral pericardium does not have somatic sensation.", "cop": 2, "opa": "Pericardiophrenic Nerve", "opb": "Phrenic Nerve", "opc": "T2 to T6 intercostal nerves", "opd": "Vagus nerve", "subject_name": "Anatomy", "topic_name": null, "id": "7ac725b5-a59d-48cc-ac6a-242ec2ce1826", "choice_type": "single"} {"question": "Ramu, 40 year old male, chronic alcoholic, diagnosed as cirrhosis, presents with a lump in the right lobe of liver. Serum AFP level is normal. Most probable diagnosis is", "exp": "This is a typical presentation of hepatocellular carcinoma (age, cirrhosis, presence of lump, all perfectly match.) The only problem is that AFP is not elevated. This should not prevent us from making a diagnosis of HCC as Schwaz writes-\"It must be kept in mind that only 60 to 75% of HCCs produce AFP; therefore, a normal serum AFP level does not rule out HCC.\" Hepatocellular adenoma and focal nodular hyperplasia (I' could not find any term as Fibrohyperplasia) are seen in women of reproductive age gp. They are associated with OCPs. Ref : Schwaz 9/e, p 1110", "cop": 2, "opa": "Fibrohyperplasia", "opb": "Hepatocellular carcinoma", "opc": "Secondaries", "opd": "Hepatocellular adenoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3a26480a-e6a5-4f5a-9911-e33cb9e428fc", "choice_type": "single"} {"question": "Left ovarian vein drains into", "exp": "Ovarian veins crosses the ureter anteromedially halfway between bifurcation of the IVC and the point in which it joins the anterolateral inferior vena cava (IVC). The left ovarian vein ascends similarly into the abdomen but drains into the left renal vein. ref - BDC 6e vol2 pg384", "cop": 1, "opa": "Left renal vein", "opb": "Internal iliac vein", "opc": "Inferior vena cava", "opd": "Azygos vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "abd96b36-d43e-45f3-8367-7625a3e5d777", "choice_type": "single"} {"question": "The role of bradykinin in process of inflammation is", "exp": "Ref Robbins 8/e p65- 66 ; 9/e p89 Bradykinin is a potent endothelium-dependent vasodilator and mild diuretic, which may cause a lowering of the blood pressure. It also causes contraction of non-vascular smooth muscle in the bronchus and gut, increases vascular permeability and is also involved in the mechanism of pain.", "cop": 4, "opa": "Vasoconstriction", "opb": "Bronchiodilatation", "opc": "Pain", "opd": "Increase in vascular permeability", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3faf163d-f453-41c0-822e-2ade3a48cb4e", "choice_type": "single"} {"question": "The marked area develops from(in green colour)", "exp": "The marked area is floor of fossa ovalis that developes from septum primum", "cop": 1, "opa": "Septum Primum", "opb": "Septum secundum", "opc": "Ostium primum", "opd": "Ostium secundum", "subject_name": "Anatomy", "topic_name": "JIPMER 2018", "id": "0c88435b-3b57-41fe-98b4-4066a3ee5c6c", "choice_type": "single"} {"question": "Sexual intercourse with another man's wife with her consent and without the consent of that man is", "exp": "Adultery Sexual intercourse with another man's wife with her consent and without the consent of that man is adultery. Man who commits the offence of adultery shall be punished with imprisonment up to 5 years or with fine or both. In such cases, the wife shall not be punishable as an abettor. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 308", "cop": 2, "opa": "Sodomy", "opb": "Adultery", "opc": "Bestiality", "opd": "Tribadism", "subject_name": "Anatomy", "topic_name": "Sexual offences and infanticide", "id": "91cea68d-dab9-4c16-9b41-5e98be145c50", "choice_type": "single"} {"question": "Stapes footplate covers", "exp": "B. i.e. Oval window", "cop": 2, "opa": "Round window", "opb": "Oval window", "opc": "Inferior sinus tympani", "opd": "Pyramid", "subject_name": "Anatomy", "topic_name": null, "id": "59ac6f0c-1ab9-4a49-86e4-c2baaa43be8b", "choice_type": "single"} {"question": "Vitum's sign is seen in", "exp": ".", "cop": 4, "opa": "AR", "opb": "MS", "opc": "AS", "opd": "TR", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0fc5a53f-3cec-42d4-b55a-c2f55b6b2f21", "choice_type": "single"} {"question": "Procalcitonin is used as marker of", "exp": "ref Harrison 18/e p3419 Procalcitonin is an acute phase reactant which is now useful for being a marker of sepsis Procalcitonin (PCT) is a biomarker that exhibits greater specificity than other proinflammatory markers (eg, cytokines) in identifying patients with sepsis and can beused in the diagnosis of bacterial infections", "cop": 4, "opa": "Cardiac dysfunction in acute coronary syndrome", "opb": "Menstrual perodicity", "opc": "Pituitary function", "opd": "Sepsis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "775c3602-1ecb-4cb6-9c6c-940558a97fef", "choice_type": "single"} {"question": "Following cells are responsible for acid secretion in kidney", "exp": ".", "cop": 1, "opa": "I cells", "opb": "P cells", "opc": "Mesangial cells", "opd": "Pericytes", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "6f0a1139-9834-47b9-bc01-616af4c7f7b4", "choice_type": "single"} {"question": "Length of female urethra", "exp": "The female urethra, about 4 cm in length, is fused with the anterior wall of the vagina. It ends between the clitoris and the vagina. The male urethra, about 20 cm in length, comprises three pas: prostatic, membranous, and spongy Ref - BDC 6e vol2 pg379", "cop": 2, "opa": "2cm", "opb": "4cm", "opc": "6cm", "opd": "8cm", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c0a0b020-8533-4cce-82fb-3397b4264adc", "choice_type": "single"} {"question": "Most common presentation of cardiac Lupus is", "exp": ".", "cop": 2, "opa": "Myocarditis", "opb": "Pericarditis", "opc": "Aoic regurgitation", "opd": "Libman sacks endocarditis", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b83b623d-cee1-4d88-83cc-bbabb2fd478f", "choice_type": "single"} {"question": "cleft palate is the side effect of", "exp": "- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential - CLEFT PALATE, FINGER NAIL HYPOLASIA, - SPINA BIFIDA Ref, kaplon and sadock, synopsis of psychiatry, 11 th edition,pg no.935", "cop": 1, "opa": "carbamezepine", "opb": "clozapine", "opc": "risperidone", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "1c5d91d8-3a19-4ce8-b54e-03b163bf8867", "choice_type": "single"} {"question": "Cephalic vein drains into", "exp": "CEPHALIC VEIN:-&;begins as continuation of lateral end of dorsal venous arch. Crosses roof of anatomical snuff box. Ascends On radial border of forearm, continues in front of elbow,along biceps. Pierces deep fascia at lower border of pectoralis major. Runs in cleft between deltoid and pectoralis major. Pierces clavipectoral fascia. Drains into axillary vein.&; Cephalic vein is accompanied by lateral cutaneous nerve of forearm. {Reference: vishram singh, pg no.98}", "cop": 3, "opa": "Brachial vein", "opb": "Subclan vein", "opc": "Axillary vein", "opd": "Inferior vena cava", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e22b46e0-7b70-4bb9-a939-e91981200376", "choice_type": "single"} {"question": "The arrow indicating the anatomical identification of structure", "exp": "(C) 3rd ventricle", "cop": 3, "opa": "First ventricle", "opb": "2nd ventricle", "opc": "3rd ventricle", "opd": "4th ventricle", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "04ffc86e-e161-4668-8d21-a3c503333802", "choice_type": "single"} {"question": "Best investigation to differentiate scar from recurrence after mastectomy done for carcinoma breast", "exp": "PET Scan Investigation of choice for recurrences in scarred breast. UUseful in multifocal disease and in helping detect axillary involvement Ref:Sabiston 20th edition pgno : 826-828", "cop": 3, "opa": "MRI", "opb": "CT", "opc": "PET Scan", "opd": "Mammography", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "ab5b6ed7-a717-4328-8946-fe57fbc37fb4", "choice_type": "single"} {"question": "The last organ to putrefy after death is", "exp": "As general rule organs show putrefactive changes in the following order 1) Larynx and trachea2) Stomach, intestines, and spleen3) Liver, lungs4) Brain5) Hea6) Kidney, bladder, uterus, prostate7) Skin, muscle, tendon8) Bones", "cop": 2, "opa": "Hea", "opb": "Prostate", "opc": "Stomach", "opd": "Brain", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "5549fabd-d15a-4694-81da-79587e639fe0", "choice_type": "single"} {"question": "mood stabilizer used in the tretament of rapid cycling", "exp": "Lamotrigine is a mood stabilizer which works best in BIPOLAR DEPRESSION Lithium is a mood stabilizer which works best in BIPOLAR MANIA valproate is a mood stabilizer which works best in RAPID CYCLING ref. kaplon and sadock, synopsis of psychiatry, 11 thedition, pg no.935", "cop": 1, "opa": "vaproate", "opb": "lithium", "opc": "carbamezepine", "opd": "lamotrigine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "84b19255-3121-471c-ad86-c9ae99b02bf1", "choice_type": "single"} {"question": "Irresistible desire to buy something is", "exp": "Oniomania Irresistible desire to buy things (shopping addiction) Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 360", "cop": 3, "opa": "Mutilomania", "opb": "Dipsomania", "opc": "Oniomania", "opd": "Trichotilomania", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "bc1791ba-85f2-48c7-a5b4-97bd371698bf", "choice_type": "single"} {"question": "Xeroderma pigmentosum is caused due to group of closely related abnormalities in", "exp": "Ref Harrison 17/e p387; Robbins 7/e p287; 9/e 314 Xeroderma Pigmentosum. Xeroderma pigmentosum (XP) is the classical human recessive disorder caused by defective nucleotide excision repair of DNA damage, including pyrimidine dimers induced by UV radiation. Symptoms may include a severe sunburnafter only a few minutes in the sun, freckling in sun exposed areas, dry skin and changes in skin pigmentation. Nervous system problems, such as hearing loss, poor coordination, loss of intellectual function and seizures, may also occur.Complications include a high risk of skin cancer, with about half having skin cancer by age 10 without preventive effos, and cataracts. There may be a higher risk of other cancers such as brain cancers.[", "cop": 3, "opa": "Mismatch repair", "opb": "Base excision repair", "opc": "Nucleotide excision repair", "opd": "SOS repair", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "858c9b85-1685-4b29-82d1-dae5c91ef938", "choice_type": "single"} {"question": "CYP 3A4 enzyme are affected by", "exp": "CYP3A4 cary out biotransformation of large numberof drugs. The inhibition of this isoenayme by erythromycin, clarithromycin, ketoconazole, itraconazole etc is responsible for impoant drug interactions with terfenadine, astemizole and cisapride. Rifamps barbiturates and other anticonvulsants are impoant inducers. Ref-KDT 7/e p24", "cop": 2, "opa": "Fexofenadine", "opb": "Phenytoin", "opc": "Carbamazepine", "opd": "Pencillin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9739e5db-d056-4758-bfe3-5d467a8f94a4", "choice_type": "single"} {"question": "Chassaignac's tubercle lies at level of", "exp": "The anterior tubercle of the transverse process of the sixth cervical veebra is the largest of all such processes and is called the carotid tubercle (of Chassaignac). The common carotid aery can be best pressed against I this tubercle, deep to the anterior border of the I sternocleidomastoid muscle. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 6th edition pg 300", "cop": 1, "opa": "Erb's point", "opb": "Stellate ganglion", "opc": "Atlas", "opd": "Odontoid process", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "6caef923-0bd7-4248-b990-79cc2679b61f", "choice_type": "single"} {"question": "The function of 8th cranial N. is related to", "exp": "Balance The 8th cranial N. or vestibulo cochlear N. has two divisions:Cochlear division -4 concerned with hearingVestibular division concerned with equilibrium & balance", "cop": 4, "opa": "Smell", "opb": "Taste", "opc": "Touch", "opd": "Balance", "subject_name": "Anatomy", "topic_name": null, "id": "93b0af0a-07db-49f4-9517-903bba8b8499", "choice_type": "single"} {"question": "Generalized necrotizing lymphadenopathy is", "exp": ".", "cop": 2, "opa": "Kimura disease", "opb": "Kikuchi disease", "opc": "Non hodgkins lymphoma", "opd": "Castle mans disease", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "73ae5773-0592-412a-acea-522bd7be340b", "choice_type": "single"} {"question": "Structure NOT passing through esophageal opening", "exp": "At T8 - IVC hiatus in central tendon through which IVC and few branches of Rt. phrenic nerve passes At T10 - Oesophageal opening is present through which passes: Esophagus Esophageal branch of left gastric aery Anterior and posterior vagal trunk At T12 - Aoic hiatus posterior to diaphragm formed by median arcuate ligament through which passes: Aoa Thoracic duct Azygous vein", "cop": 2, "opa": "Esophagus", "opb": "Phrenic nerve", "opc": "Vagus nerve", "opd": "Gastric aery branches", "subject_name": "Anatomy", "topic_name": "Umblicial cord and diaphragm", "id": "cf225b0b-9e41-4f41-9e6a-55d6bd10e2a7", "choice_type": "single"} {"question": "Calcium channel blocker with maximum efficiency on conduction on hea is", "exp": "Refer katzung 11e p181 Verapamil, is a medication used for the treatment of high blood pressure, angina, and supraventricular tachycardia. It may also be used for the prevention of migraines and cluster headaches. It is given by mouth or by injection into a vein", "cop": 3, "opa": "Phenylamine", "opb": "Nifedipine", "opc": "Verapamil", "opd": "Diltiazem", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dc3149fc-f806-4acc-8019-0c616f01069d", "choice_type": "single"} {"question": "Caseous necrosis in granuloma are not found in", "exp": "ref Robbins 7/e p73,9/e p98 It is also seen in wegener's granulomatosis. Caseous necrosis is a form of cell death in which the tissue maintains a cheese-like appearance. The dead tissue appears as a soft and white proteinaceous dead cell mass. CausesEdit Frequently, caseous necrosis is encountered in the foci of tuberculosis infections. It can also be caused by syphilis and ceain fungi. A similar appearance can be associated with histoplasmosis, cryptococcosis, and coccidioidomycosis. AppearanceEdit In caseous necrosis no histological architecture is preserved. On microscopic examination with H&E staining, it is characterized by acellular pink areas of necrosis surrounded by a granulomatousinflammatory process. When the hilar lymph node for instance is infected with tuberculosis and leads to caseous necrosis, its gross appearance can be a cheesy tan to white, which is why this type of necrosis is often depicted as a combination of both coagulative and liquefactive necrosis. However, in the lung, extensive caseous necrosis with confluent cheesy tan granulomas is typical. The tissue destruction is so extensive that there are areas of cavitation (also known as cystic spaces). See Ghon's complex", "cop": 2, "opa": "TB", "opb": "Leprosy", "opc": "Histoplasmosis", "opd": "CMV", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "35b5eeb5-19fe-4ef7-9478-9d9242c25ff1", "choice_type": "single"} {"question": "Isthmus of thyroid gland lies against following tracheal rings", "exp": "The thyroid gland lies against veebrae C5, C6, C7 and T1 embracing the upper pa of the trachea Each lobe extends from the middle of thyroid cailage to the fouh to fifth tracheal ring The isthmus extends from the second to fouh tracheal ring. Ref BDC volume 3,Sixth edition pg 141", "cop": 1, "opa": "4-Feb", "opb": "3-Feb", "opc": "5-Feb", "opd": "3-Jan", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "a9333f47-50ba-4f94-bc11-69f49f80d269", "choice_type": "single"} {"question": "Inferior meatus drains", "exp": null, "cop": 1, "opa": "Nasolacrimal duct", "opb": "Frontal sinus", "opc": "Posterior ethmoidal sinus", "opd": "Maxillary sinus", "subject_name": "Anatomy", "topic_name": null, "id": "b11edb28-d8a6-4691-adb3-4264b13bed0d", "choice_type": "single"} {"question": "Temporalis muscle is inserted into", "exp": null, "cop": 2, "opa": "Condylar process", "opb": "Coronoid process", "opc": "Lingula", "opd": "Ramus of mandible nerve", "subject_name": "Anatomy", "topic_name": null, "id": "b72dee94-3423-4367-8309-16f22ae68d2d", "choice_type": "single"} {"question": "Cranial nerve involved in sarcoidosis is", "exp": ".", "cop": 4, "opa": "2nd", "opb": "3rd", "opc": "5th", "opd": "7th", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1c132e39-993d-445c-8585-b498660ded63", "choice_type": "single"} {"question": "Mapleson's classification of an anaesthetic breathing system", "exp": "The Mapleson D may be described as a co-axial modification of the basic T-piece system, developed to facilitate scavenging of waste anaesthetic gases. Function: The Bain circuit is a modification of the Mapleson D system. It is a co-axial system in which the fresh gas flows through a narrow inner tube within the outer corrugated tubing. Essentially, the Bain circuit functions in the same way as the T-piece, Except that the tube supplying fresh gas to the patient is located inside the reservoir tube. Inspiration - The patient inspires fresh gas from the outer reservoir tube. Expiration - The patient expires into the reservoir tube. Although fresh gas is still flowing into the system at this time, it is wasted, as it is contaminated by expired gas. Expiratory pause - Fresh gas from the inner tube washes the expired gas out of the reservoir tube, filling it with fresh gas for the next inspiration. Spontaneous ventilation Normocarbia requires a fresh gas flow of 200-300 ml/kg. Controlled ventilation A fresh gas flow of only 70 ml/kg is required to produce normocarbia. Bain and Spoerel have recommended the following: 2 L/min fresh gas flow in patients <10 kg 3.5 L/min fresh gas flow in patients 10-50 kg 70 ml/kg fresh gas flow in patients >60 kg The recommended tidal volume is 10 ml/kg and respiratory rate is 12-16 breaths/minute", "cop": 2, "opa": "Describes four systems A, B, C, D", "opb": "Classifies the Bain system as Mapleson", "opc": "Describes the T-piece as M", "opd": "Describes the T-piece system as requiring a fresh gas flow rate of 1.5 - 2 times the minute volume.", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5269a34a-aeed-4d61-a6e2-2a1e4961ea07", "choice_type": "single"} {"question": "If circumflex artery gives the posterior interventricular branch, this circulation is described", "exp": "In about 10% of hearts, the right coronary is rather small and is not able to give the posterior interventricular branch.\nIn these cases the circumflex artery, the continuation of left provides the posterior interventricular branch and called left dominant.", "cop": 2, "opa": "Right dominance", "opb": "Left dominance", "opc": "Codominance", "opd": "Undetermined", "subject_name": "Anatomy", "topic_name": null, "id": "ba0e24e6-3b49-4933-8dbe-4ea3ff29686a", "choice_type": "single"} {"question": "The axis of abduction and adduction of digits passes through the centre of", "exp": "The third metacarpal is the longest and the axis of abduction and adduction passes through its centre.Ref: Chaurasia; Volume 2; 6th edition; Page no: 31", "cop": 2, "opa": "2nd metacarpal", "opb": "3rd metacarpal", "opc": "4th metacarpal", "opd": "5th metacarpal", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "4cb87390-5312-44e9-ac38-5c4244eeb5cc", "choice_type": "single"} {"question": "Rupture of Berry aneurysm causes", "exp": "Subarachnoid hemorrhage Rupture of sacular Berry aneurysm which is usually located in one of the vessels in the Circle of Willis. Berry aneurysm occurs due to congenital defect or degenerative change in the muscle layer and internal elastic lamina. Only the initimal layer and adventitia of the aery form the dome of the aneurysm. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 174", "cop": 3, "opa": "Extradural hemorrhage", "opb": "Subdural hemorrhage", "opc": "Subarachnoid hemorrhage", "opd": "Intracerebral hemorrhage", "subject_name": "Anatomy", "topic_name": "Special topics", "id": "0d8bd893-f6a2-4b51-9374-4b267eb52406", "choice_type": "single"} {"question": "A 40 year old male underwent coronary aery bypass grafting. During the procedure the surgeon applied clamp to the vessel lying anterior to thhe transverse pericardial sinus. The vessel is", "exp": "The aoa lies anterior to the transverse pericardial sinus. The reflections of the serous pericardium are arranged as two tubes- one enclosing the aoa and the pulmonary trunk and the other enclosing the vena cavae and the four pulmonary veins. The zone of reflection surrounding the vein is j-shaped and the cul-de-sac formed within the j is the oblique pericardial sinus. This lies posterior to the left atrium. The transverse sinus is a passage between the two 'tubes'. The aoa and the pulmonary trunk lie anterior and the superior vena cava and the atria lie posterior to it. Ref: Gray's Anatomy 41st edition Pgno: 995", "cop": 1, "opa": "Aoa", "opb": "Pulmonary aery", "opc": "Inferior vena cava", "opd": "Superior vena cava", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "d251b6d9-475f-4406-83f6-97b9a6e0507f", "choice_type": "single"} {"question": "The receptor of joint capsule and ligaments is", "exp": "Receptors can be classified into rapidly adapting (phasic) receptors and slowly adapting (tonic) receptors.Rapidly adapting receptorsSlowly adapting receptorsCutaneous mechanoreceptors such as:Meissner corpuscles (respond to changes in texture and slow vibrations)Pacinian corpuscles (respond to deep pressure and fast vibration)Cutaneous mechanoreceptors such as:Merkel cells (respond to sustained pressure and touch)Ruffini endings (respond to sustained pressure)ProprioceptorsNociceptors (free nerve endings - respond to thermal, chemical and thermal noxious stimuli)(Refer: Ganong&;s Review of Medical physiology 24th edition, pg no: 158)", "cop": 1, "opa": "Slow adapting", "opb": "Fast adapting", "opc": "Different to slow and fast adapting", "opd": "Non adapting", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "24860cfd-9774-4c65-87df-a903007e4c99", "choice_type": "single"} {"question": "Eye of the hand is", "exp": "The median nerve controls coarse movements of the hand, as it supplies most of the long muscles of the front of the forearm. It is, therefore, called the labourer&;s nerve. It is also called \"eye of the hand\" as it is sensory to most of the hand.Reference: Vishram Singh Anatomy; 2nd edition; Page no: 177", "cop": 1, "opa": "Median Nerve", "opb": "Ulnar Nerve", "opc": "Radial Nerve", "opd": "Posterior Interosseous Nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "85026aba-da80-43ca-b605-63c768287594", "choice_type": "single"} {"question": "Osteoclast are stimulated by", "exp": "Refer Robbins page no 1207-1208 Parathyroid hormone related protein (PTHrP) is a local factor, expressed by perichondrial stromal cells and early proliferating chondrocytes, that activates the PTH receptor and maintains proliferation of chondrocytes.", "cop": 2, "opa": "Thyroxine", "opb": "PTH", "opc": "Calcitonin", "opd": "Estrogen", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "6d9b1da1-3ccc-4e83-93d2-25ea20ee86a5", "choice_type": "single"} {"question": "A Toxic doses, zero order kinetics is seen in", "exp": "Phenytoin follows nonlinear (or zero-order) kinetics at therapeutic concentrations, because the rate of metabolism is close to the maximum capacity of the enzymes involved Ref-KDT 6/e p31", "cop": 2, "opa": "Pencillin", "opb": "Phenytoin", "opc": "Valproate", "opd": "Carbamazepine", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "33411849-200f-4a5c-85a6-3d69fd9a312a", "choice_type": "single"} {"question": "Water hammer pulse is seen", "exp": "Ref Harrison 19 th ed pg 1535 A rapidly rising \"water-hammer\" pulse, which col- lapses suddenly as aerial pressure falls rapidly during late systole and diastole (Corrigan's pulse), and capillary pulsations, an alternate flushing and paling of the skin at the root of the nail while pressure is applied to the tip of the nail (Quincke's pulse), are characterist", "cop": 2, "opa": "Aoic stenosis", "opb": "Aoic regurgitation", "opc": "Aoic stenosis and aoic regurgitation", "opd": "Mitral regurgitation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5ba1254f-af27-48e1-9b26-58af5f3b2d54", "choice_type": "single"} {"question": "Medial aspect of great toe supplied by", "exp": "DEEP PERONEAL:- Muscular branches to muscles of anterior compament of leg: Tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus teius.Extensor digitorum brevis Cutaneous: dorsal digital nerves for adjacent sides of big toe and second toe. Aicular branches:Ankle joint, tarsal joints, tarsometatarsal joints and metatarsophalangeal joint of big toe. COMMON PERONEAL:-Branch of sciatic nerve Root value:L4,L5,S1,S2 Branches:Muscular branch: sho head of biceps Cutaneous:lateral cutaneous nerve of calf.Aicular: superior lateral,inferior lateral and recurrent genicular .Terminal branches: superficial and deep peroneal. SUPERFICIAL PERONEAL:-Muscular branches: peroneus longus and brevis Cutaneous branches:Digital branches to medial side of big toe, adjacent sides of 2nd and 3rd, 3rd and 4th, and 4th and 5th toes. {Reference:BDC 6E page no.173,174}", "cop": 2, "opa": "Superficial peroneal nerve", "opb": "Deep peroneal nerve", "opc": "Common perioneal palsy", "opd": "Sural nerve", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "b5a57cac-f14b-42a3-912e-e22ffe635d88", "choice_type": "single"} {"question": "A 30 year old primipara in labor with transverse lie treatment of choice is", "exp": "Patients in labor with transverse lie can be managed by external cephalic version followed by surgical rupture of membrane But it is impoant to note that the patient is primigravuda with age 30years i.e, elderly primi so ECV is contraindicated This patient requires emergency cesaream section", "cop": 2, "opa": "Internal cephalic version", "opb": "Emergency cesarean section", "opc": "Wait and watch", "opd": "External cephalic version", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "f6dc814c-4c1e-445a-a238-6eff973434ca", "choice_type": "single"} {"question": "Crooke's hyaline body is present in", "exp": "Ref Robbins 8/e p 1149", "cop": 2, "opa": "Yellow fever", "opb": "Basophil cells of pituitary gland in Cushing syndrome", "opc": "Parkinsonism", "opd": "Huntington 's disease", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e0d688cf-0ae8-487e-aebf-09d51b0f52aa", "choice_type": "single"} {"question": "Neurovascular bundle in axilla is surrounded by sheath derived from", "exp": "The neurovascular bundle in axilla is covered by axillary sheath which is derived from preveebral fascia. Reference : BD chaurasia, 7th edition, page no 50-Fig.4.5 & page no 60-Facts to remember", "cop": 1, "opa": "Preveebral fascia", "opb": "Pretracheal fascia", "opc": "Clavipectoral fascia", "opd": "Axillary sheath", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "17b3f3f0-3f07-4c93-9724-7fc56016d36b", "choice_type": "single"} {"question": "Adductors of vocal cord", "exp": "movements and muscle 1. elevation of larynx: thyrohyoid, mylohyoid 2. depression of larynx: sternothyroid, sternohyoid 3.opening inlet of larynx: thyroepiglottic 4. closing inlet of larynx: aryepiglottic 5.abductor of vocal cords: posterior cricoarytenoid only 6. adductor of vocal cords: lateral cricoarytenoid transverse and oblique arytenoids Ref BDC volume 3; sixth edition pg 258", "cop": 2, "opa": "Posterior cricoarytenoids", "opb": "lateral cricoarytenoids", "opc": "Transverse arytenoids", "opd": "V occalis", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "acd20371-3377-4384-828e-3dea874fc862", "choice_type": "single"} {"question": "Most common site of Ewings sarcoma", "exp": "Most common site of Ewings sarcoma is diaphysis of femur followed by diaphysis of tibia Refer : Textbook of skeletal oncology p 315", "cop": 4, "opa": "Upper end of tibia", "opb": "Shaft of tibia", "opc": "Lower end of femur", "opd": "Shaft of femur", "subject_name": "Anatomy", "topic_name": null, "id": "b2ad36f4-84af-47d8-a2e8-c746fc25b994", "choice_type": "single"} {"question": "Mikulicz cell and Russell bodies are seen in", "exp": "Granulomatous disease of the nose BacterialFungalUnspecified causeRhinoscleroma Syphilis TuberculosisLupusLeprosy RhinosporidiosisAspergillosis Mucormycosis CandidiasisHistoplasmosis Blastomycosis Wegner's granulomatosisNon healing midline granuloma Sarcoidosis Churg Strauss syndrome RhinoscleromaAgent - Klebsiella rhinoscleromatisSite - nose, nasopharynx, oropharynx, larynx, trachea, bronchi Atrophic stageFoul smelling purulent nasal dischargeGranulomatous stage Subdermal infiltration of lower pa of external nose & upper lip - woody feelRubbery nodules - Tapir nose Cicatricial stage Stenosis of nares Distoion of upper lip Adhesions of nose, nasopharynx, oropharynx Subglottic stenosisNose deformity - Hebra nose Soft palate deformity - Gothic arch deformity Diagnosis Biopsy - infiltration of submucosa with plasma cells, lymphocytes, eosinophils, Mikulicz cells ( large foam cells with central nucleus & vacuolated cytoplasm containing causative bacilli ) & Russell bodies(homogenous eosinophilic inclusion bodies found in plasma cells)The culture of the organism Treatment - Streptomycin (1g/day) & tetracycline (2g/day) for 4 - 6 weeks (Refer: PL Dhingra, Textbook of Ear, Nose, Throat, 6thedition, pg no: 156)", "cop": 1, "opa": "Rhinoscleroma", "opb": "Rhinophyma", "opc": "Rhinosporidiosis", "opd": "Plasma cell disorder", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "054b188b-2b25-4ed8-89e5-fca2330f396c", "choice_type": "single"} {"question": "Ascending pharyngeal artery is a branch of", "exp": null, "cop": 2, "opa": "Middle branch of ECA.", "opb": "Medial branch of ECA.", "opc": "Terminal branch of ECA.", "opd": "Anterior branch of ECA.", "subject_name": "Anatomy", "topic_name": null, "id": "32c0ab5e-1d61-45eb-9735-ab83bf99a96e", "choice_type": "single"} {"question": "The embryonic vascular layer of the eye is derived from", "exp": "(Mesoderm) (8-9-Khurana 4th) (5-Parson 20th)Structures derived from the Embryonic layers1. Surface ectoderm2. Neural ectoderm(a) The crystalline lens(b) Epithelium of the cornea(c) Epithelium of the conjunctiva(d) Lacrimal glands(e) Epithelium of eyelids and its derivatives, viz.: cilia, tarsal glands, and conjunctival glands.(f) Epithelium lining the lacrimal apparatus (Lacrimal glands, Tarsal glands)(a) Retina with its pigment epithelium(b) Epithelial layers of ciliary body(c) Epithelial layers of iris(d) * Sphincter and dilator papillae muscles(e) Optic nerve (neuroglia and nervous elements only)(f) Melanocytes - Retinal pigment epithelium(g) Secondary vitreous(h) Ciliary zonules3. Associated paraxial mesoderm(a) ** Blood vessels of choroid, iris, ciliary vessels, central retinal artery, other vessels (Vascular endothelium of eye and orbit)(b) Primary vitreous(c) Substantia propria, Descemet's membrane, and endothelium of cornea(d) The sclera(e) Stroma of iris(f) Ciliary muscle(g) Sheaths of optic nerve(h) Extraocular muscle(i) Fat, ligaments and other connective tissue structures of the orbit(j) Upper and medial walls of the orbit(k) Connective tissue of the upper eyelid4. Visceral mesoderm of maxillary process below the eye(a) Lower and lateral walls of orbit(b) Connective tissue of the lower eyelid.", "cop": 2, "opa": "Neural crest", "opb": "Mesoderm", "opc": "Ectoderm", "opd": "Surface ectoderm", "subject_name": "Ophthalmology", "topic_name": "Anatomy", "id": "9f8d8531-cb22-47ea-87c4-f97def5bb075", "choice_type": "single"} {"question": "If the seventh nerve is damaged on the right side of the face", "exp": null, "cop": 2, "opa": "the muscles of mastication would be denervated", "opb": "the\tmuscles\tof\tfacial\texpression\twould\tbe denervated", "opc": "taste from the right anterior two thirds of the tongue would not be affected", "opd": "sympathetic\tfibre\tto\tsalivary\tgland\twould\tbe interrupted", "subject_name": "Anatomy", "topic_name": null, "id": "4cd83c5b-3240-40fe-8055-23dd1d46f6e7", "choice_type": "single"} {"question": "Glands of Van Ebner are present in", "exp": "The minor salivary glands are numerous and are widely distributed in the mucosa of oral cavity. Some of the minor salivary glands are the Von Ebner's gland in tongue, buccal glands in cheeks and labial glands in lips. REF : Inderbir Singh's Textbook of Human Histology, Seventh edition, pg.no., 251.", "cop": 3, "opa": "Cervix", "opb": "Penile uretha", "opc": "Tongue", "opd": "Vagina", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "66c64f3b-5522-4646-b243-c2b472642941", "choice_type": "single"} {"question": "Commonest stone in case of UTI", "exp": "Phosphate or struvite stones are infection stones associated with urea-splitting organisms i.e. Proteus, Pseudomonas, Providencia, Klebsiella, Staphylococci and Mycoplasma. The high ammonium concentration desired from urea-splitting organisms results in an alkaline urinary pH, required for the precipitation of phosphate crystals. Ref : Bailey & Love 25/e p1296", "cop": 1, "opa": "Phosphate", "opb": "Urate", "opc": "Cysteine", "opd": "Calcium oxalate", "subject_name": "Anatomy", "topic_name": "Urology", "id": "9705a10d-a159-4160-8cb8-84a1aed061a6", "choice_type": "single"} {"question": "The largest organ of the body is", "exp": "The liver is the largest gland in the body and has a wide variety of functions (265-Snell 7th )\nThe liver is the largest gland in the body. (283-BDC-2)\nFemer is the longest and the strongest bone of the body (16-B DC-2)\nSkin is the largest organ of the body (278-K- Sembulingam physiology)\nSkin is considered as the largest sense organ in the body it has many nerve endings, which are specialized to form cutaneous receptors (281-K. Sembulingam physiology 3rd )", "cop": 2, "opa": "Liver", "opb": "skin", "opc": "Gluteus maximus", "opd": "Femur", "subject_name": "Anatomy", "topic_name": null, "id": "311ea464-f79d-4208-a70c-d5fd4c9f423d", "choice_type": "single"} {"question": "A patient presented with pain in right testis Examination reveals bay of worms suggestive of varicocele. Right testicular vein drains into", "exp": "Right testicular vein drains into IVC\nLeft testicular vein drains into left renal vein", "cop": 2, "opa": "Hemiazygous vein", "opb": "IVC", "opc": "Inferior mesentric vein", "opd": "Renal vein", "subject_name": "Anatomy", "topic_name": null, "id": "42c6388c-9b27-4132-a5cb-8ba26c5f075a", "choice_type": "single"} {"question": "Line from midinguinal point to adductor tubercle represent", "exp": "Femoral aery surface marking:- Upper two third of the line joining midinguinal point and adductor tubercle. Mid inguinal point: a point midway between the anterior superior iliac spine and pubic symphysis. Adductor tubercle: lies at lower end of the cord like tendon of adductor magnus. The tendon can be felt in a groove just behind the prominence of vastus medialis when the thigh is semiflexed, abducted and laterally rotated. Upper 1/3 rd of line-upper half of line lying in femoral triangle. Middle 1/3 rd- lower half of aery lying in adductor canal. Lower 1/3 rd- descending genicular and saphenous branches of the aery. {Reference: BDC 6E pg no. 165}", "cop": 2, "opa": "Inferior epigastric aery", "opb": "Femoral aery", "opc": "Superior epigastric aery", "opd": "Saphenous vein", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "449ecc11-8b3c-4ead-b645-44770e9eff3d", "choice_type": "single"} {"question": "Maintenance of high urinary pH is impoant during methotrexate treatment because", "exp": "Ref-KDT 6/e p823 Methotrexate is a weak acid and basic reabsorbed in acids urinary PH. Higher plasma concentration may result in toxicity. Therefore to decrease the reabsorptiion through renal tubes urinary pH must be maintained", "cop": 4, "opa": "Bladder irritation is reduced", "opb": "It decreases renal tubular secretion of methotrexate", "opc": "Leucovorin toxicity is increased in a dehydrated patient", "opd": "Methotrexate is a weak acid", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "f0efb26c-cd6d-4290-ac29-29b5db4f43f3", "choice_type": "single"} {"question": "Stomach contents will have smell of bitter almond in", "exp": "Postmoem appearance Froth may be present at the mouth and nostrils. Postmoem staining and blood will have bright red color. In a case of suspected cyanide poisoning, cranial cavity has to be opened first because the odour of hydrocyanic acid is well evident in the brain. All the internal organs will be congested. Lungs will be congested and edematous. There may be corrosion of the mucosa of the mouth esophagus and stomach. Stomach will be intensely congested and the contents may have the smell of bitter almond. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 473", "cop": 3, "opa": "Sulphuric acid poisoning", "opb": "OP poisoning", "opc": "Cyanide poisoning", "opd": "Arsenic poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "6b766d50-c68b-4c2e-88a7-3669a2bfab74", "choice_type": "single"} {"question": "Eversion is", "exp": "- Eversion - Movement of sole of the foot outward. Foot eversion occurs at subtalar joint by Peroneus longus, Peroneus brevis and Peroneus Teius. - Inversion: Movement of the sole of the foot inward so that the soles face toward each other. Done by Tibialis anterior and Tibialis posterior.Additional information:", "cop": 2, "opa": "Sole of the foot upward", "opb": "Sole of the foot outward", "opc": "Sole of the foot inward", "opd": "Sole of the foot downward", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "2f38bdd0-4aa8-4723-bea7-6686f7923bf4", "choice_type": "single"} {"question": "Dorello's canal transmits in tip of temporal bone", "exp": "Dorello canal is an opening to cavernous sinus that transmit abducent nerve underneath the superior petrosal sinus.", "cop": 4, "opa": "Middle maningeal aery", "opb": "Mandibular nerve", "opc": "Superior alveolar branch of maxillary", "opd": "Abducent nerve", "subject_name": "Anatomy", "topic_name": null, "id": "cd75589d-2227-4658-bb29-c901855043cf", "choice_type": "single"} {"question": "In after coming head the following bone is perforated during craniotomy", "exp": "Craniotomy is perforating the fetal skull and evacuating the contents and then delivering the fetal pas. In after coming head in breech occipital bone is the perforation site", "cop": 1, "opa": "Occiput", "opb": "Parietal", "opc": "Palate", "opd": "Frontal", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "8f39bd9b-d5a2-4703-9ee7-2013b32d5e16", "choice_type": "single"} {"question": "Fleischer's ring is seen in;", "exp": "KERATOCONUS Non -Inflammatory central corneal thinning Young male with constantly changing power of glasses with myopia & high cylinder SIGNS IN KERATOCONUS Munson sign. Scissor reflex on retinoscopy (Earliest Clinical Sign) Enlarged corneal nerves-lower lid indentation on downgaze. Oil droplet reflex. Rizutti's sign Acute Hydrops - aqueous accumulated in stroma Fleischer ring-Paial or complete iron deposition ring in deep epithelium encircling the base of the cone. Characteristic in eyes with keratoconus.", "cop": 1, "opa": "Keratoconus", "opb": "Keratomalacia", "opc": "Keratoglobus", "opd": "Trachoma", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "f3de22eb-c077-462d-b59f-d5a96b27a708", "choice_type": "single"} {"question": "\"Abducent nucleus\" is present in", "exp": "The abducent nucleus (CN VI) is located in the dorsomedial tegmentum of the pons. fig:-crossection atthe level of lower pons", "cop": 4, "opa": "Midbrain, at level of inferior colliculus", "opb": "Medial medulla", "opc": "Lateral medulla", "opd": "Tegmentum of pons", "subject_name": "Anatomy", "topic_name": "Brainstem, cerebellum and ventricles", "id": "84514097-25d0-4bec-8c64-fc3575e853b0", "choice_type": "single"} {"question": "The doctrine of RESRES IPSA LOQUITUR means", "exp": "The doctrine of RES IPSA LOQUITUR It means that\" The thing speaks for itself\" and the patient need not prove negligence when this doctrine is applied. The burden of proving the innocence lies upon the doctor. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 379", "cop": 1, "opa": "The facts speaks for itself", "opb": "Let the master answer", "opc": "The things have been decided", "opd": "Avoidable consequences", "subject_name": "Anatomy", "topic_name": null, "id": "29ce1d5c-9e3e-4f46-b551-259b66d4f987", "choice_type": "single"} {"question": "The superior oblique muscle is supplied by", "exp": "Superior oblique muscle is supplied by fouh cranial nerve i.e,trochlear nerve. It supplies only the superior oblique muscle of the eyeball. Superior oblique muscle helps in depression,abduction and intoion. Note: When trochlear nerve is damaged, diplopia occur looking downwards; vision is single so long as the eye look above the horizontal plane. Ref:BDC 6th edition of no.208", "cop": 2, "opa": "3rd cranial nerve", "opb": "4th cranial nerve", "opc": "5th cranial nerve", "opd": "6th cranial nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "793e5ce7-b494-4e2a-ba24-389336b11943", "choice_type": "single"} {"question": "In couinaud's classification, segment IV of liver is", "exp": "Segments nomenclature I Caudate lobe (sometimes subdivided into left and right pas called segment IX) II Left lateral superior segment III left lateral Inferior segment IV left medial segment or Quadrate lobe V Right anterior Inferior segment VI Right posterior Inferior segment VII Right posterior superior segment VIII Right anterior superior segment", "cop": 2, "opa": "Caudate lobe", "opb": "Quadrate lobe", "opc": "Right lobe", "opd": "Left lobe", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "449c4943-1a86-4465-a3d2-cd798bb00de7", "choice_type": "single"} {"question": "Genu of internal capsule carries", "exp": "The genu of internal capsule contains coiconuclear and coicospinal fibres for head and neck. It also contains, fibres of superior thalamic radiations and frontopontine fibres. (Ref: Vishram Singh textbook of neuroanatomy second edition pg-166, also refer table 14.1)", "cop": 4, "opa": "Optic radiation", "opb": "Coicospinal tract", "opc": "Coicorubral tract", "opd": "Coiconuclear tract", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "0048d669-4d36-42da-b739-c50ecadac713", "choice_type": "single"} {"question": "Stain not used for lipids", "exp": "Ref Bancrofts 's histopathology 5/e p204 Congo red is used for staining amyloid and not lipids", "cop": 2, "opa": "Oil red O", "opb": "Congo red", "opc": "Sudan 3", "opd": "Sudan black", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "29f2496a-7001-4d30-ae12-7040ebc7bc52", "choice_type": "single"} {"question": "Melanocytes are developed from the following", "exp": "Derivatives of neural crest: Mnemonic:SOME GAP S-Schwann cells -Skeleton of face O-odontoblasts M-Meninges(pia and arachnoid) E-Endocardial cushion G-Ganglia(autonomic and dorsal root ganglia) A-Adrenal medulla -Aoicopulmonary septum P-Pigmant cells(melanocytes) -Pharyngeal arches(nerves and cailage) -parafollicular c cells of thyroid", "cop": 4, "opa": "Ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Neural crest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fef84207-3a49-4daa-96e0-25fe053bfa5a", "choice_type": "single"} {"question": "Normal reticulocyte count at bih is", "exp": "Reticulocytes are 2 to 6 % of rbc count in the circulation at bihthey decreade to less than 1% during week after bih at which level they remain throughout life", "cop": 2, "opa": "1-2%", "opb": "2-6%", "opc": "6-10%", "opd": "30-40%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fe259918-4557-41ad-a041-a5b1e2b62b42", "choice_type": "single"} {"question": "The reduction of a physiological hernia occurs at", "exp": "Physiological hernia appears by 6 wks and gets reduced by 10 wks . Ref - pubmed.com", "cop": 4, "opa": "6th week", "opb": "7th week", "opc": "9th week", "opd": "10th week", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "679548be-4654-4886-8cae-be8f7832b390", "choice_type": "single"} {"question": "In patient with chronic pancreatitis limited to tail and body with MPD diameter 4mm, ideal treatment would be", "exp": "Surgical procedures in chronic pancreatitis Ideal procedure : DPPHR (Beger's) In presence of poal vein thrombosis : Frey's Small duct disease : V-shaped excision Disease recurrence in body and tail (after DPPHR, Whipple's or Longmire-Transverso procedure) : V-shaped drainage Disease limited to tail : Spleen - preserving distal pancreatectomy Ref: Sabiston 20th edition Pgno :1534", "cop": 4, "opa": "Stenting", "opb": "Puestow's operation", "opc": "Frey's operation", "opd": "Distal pancreatectomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "ed3c1344-acd6-479e-94fb-0a51b6411a0e", "choice_type": "single"} {"question": "Edema in nephrotic syndrome occurs due to", "exp": "Ref Robbins 8/e p922;9/e p115", "cop": 3, "opa": "Na+ and water restrictions", "opb": "Increased venous pressure", "opc": "Decreased serum albumin", "opd": "Decreased fibrinogen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1c4e97b1-4f07-4637-8e05-3c8861fa93fe", "choice_type": "single"} {"question": "Worm like filling defect is seen In", "exp": "On USG Thickened sinus, interrupted mucosal folds (earliest sign) Toous radiolucencies of variable size The \"worm-eaten\" smooth lobulated filling defects Ref: Wolfgang Radiology 2nd edition Pg no : 509", "cop": 2, "opa": "Erosive gastritis", "opb": "Esophageal varices", "opc": "CA esophagus", "opd": "Schatzki's ring", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "570599ff-a0e4-488e-8b43-2cb1ecb4559c", "choice_type": "single"} {"question": "Sistrunk's operation is used ina) Parotid tumourb) Thyroglossal fistulac) Thyroglossal cystd) Branchial fistula", "exp": "Thyroglossal Cyst Cystic swelling developed in the remnant of the thyroglossal duct or tract Present in any pa of the thyroglossal tract (extends from foramen caecum to isthmus of thyroid) Common sites Subhyoid (MC) Floor of mouth Region of thyroid cailage Suprahyoid Beneath the foramen caecum Clinical features It is a midline swelling, except in the region of thyroid cailage, where thyroglossal tract is pushed to one side, usually to the left Though its a congenital swelling MC age of presentation is between 15 and 30 years Cyst can be moved sideways but not veically Peculiar characteristics which helps in distinguishing thyroglossal cyst from other neck swelling Moves up with protrusion of tongue as the thyroglossal tract is attached to the tongue Moves with deglutition so do all thyroid swellings, subhyoid bursitis Cyst is lined by pseudostratified columnar epithelium and squamous epithelium with hetero topic thyroid tissue present in 20% of cases Complications Recurrent infections Formation of thyroglossal fistula Carcinomatous change (papillary carcinoma) Treatment Sistrunk operation : En-bloc cystectomy and excision of central hyoid bone to minimize recurrence Ref: Sabiston 20th edition Pgno :1861", "cop": 2, "opa": "c", "opb": "bc", "opc": "abd", "opd": "cd", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "8c91ab4c-1d7c-44c8-a77a-6d12aefacba3", "choice_type": "single"} {"question": "Muscle of mastication are derivative of", "exp": null, "cop": 1, "opa": "1st pharyngeal arch", "opb": "2nd pharyngeal arch", "opc": "3rd pharyngeal arch", "opd": "4th pharyngeal arch", "subject_name": "Anatomy", "topic_name": null, "id": "306050ad-7c2f-4737-a58b-e04b4dac873d", "choice_type": "single"} {"question": "Drugs used for rare diseases are known as", "exp": "An orphan drug is a pharmaceutical agent developed to treat medical conditions which, because they are so rare, would not be profitable to produce without government assistance. The conditions are referred to asorphan diseases Refer 6/e p6", "cop": 1, "opa": "Orphan drugs", "opb": "Rare drugs", "opc": "Radioactive isotopes", "opd": "Alkylating agents", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "88aae635-e4d9-4c21-ac52-91cb5b704bd3", "choice_type": "single"} {"question": "Mitral cells are seen in", "exp": "Mitral cells are neurons that are pa of the olfactory system. They are located in the olfactory bulb in the mammalian central nervous system. They receive information from the axons of olfactory receptor neurons, forming synapses in glomeruli. Axons of the mitral cells transfer information to a number of areas in the brain, including the piriform coex, entorhinal coex, and amygdala. Mitral cells receive excitatory input from olfactory sensory neurons and external tufted cells on their primary dendrites, whereas inhibitory input arises either from granule cells onto their lateral dendrites and soma or from periglomerular cells onto their dendritic tuft. Mitral cells together with tufted cells from an obligatory relay for all olfactory information entering from the olfactory nerve.", "cop": 1, "opa": "Olfactory bulb", "opb": "Basal ganglia", "opc": "Hippocampus", "opd": "Hypothalamus", "subject_name": "Anatomy", "topic_name": "Neuroanatomy 1", "id": "1ef6dfbe-6186-43d5-b3da-eb97ac8a5775", "choice_type": "single"} {"question": "Unpaired muscle of perineal body among the following is", "exp": "The two Unpaired muscles of perineal body are\n\nLongitudinal muscle of anal canal\nExternal and sphincter", "cop": 2, "opa": "Bulbospongiosus", "opb": "Longitudinal muscle of anal canal", "opc": "Deep transverse perineal muscle", "opd": "Levator Ani", "subject_name": "Anatomy", "topic_name": null, "id": "4019ce1c-5c35-474f-8625-f90fdc51688c", "choice_type": "single"} {"question": "Collecting pa of kidney of derived from", "exp": ".", "cop": 3, "opa": "Metanephros", "opb": "Mesonephros", "opc": "Ureteric bud", "opd": "Wolffian duct", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "6b553d2d-be27-44a6-94f3-8d771f085006", "choice_type": "single"} {"question": "Deep venous system of brain consist of", "exp": "It is single median vein formed by union of 2 internal cerebral vein. along with inferior petrosal sinus terminate in straight sinus. Its tributaries are basal vein, veins from pineal body, colliculus, cerebellum& occipital lobes. Ref: Gray's 40e/p256", "cop": 3, "opa": "Superior sagittal sinus with straight sinus", "opb": "Inf. Sagittal sinus with straight sinus", "opc": "Internal cerebral veins", "opd": "Basilar vein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f35a21f2-6dba-4c4b-a53f-ae9bbe1811d3", "choice_type": "single"} {"question": "Common cause of acute osteomyelitis is DLETE", "exp": "Hematogenous osteomyelitis is the commonest form of osteomyelitis and most common source if bone and joint infection is Hematogenous Refer Maheshwari 6th/e 168", "cop": 4, "opa": "Trauma", "opb": "Surgery", "opc": "Fungal infection", "opd": "Hematogenous spread", "subject_name": "Anatomy", "topic_name": null, "id": "d5883708-1fe7-4098-b776-b64f2ba3dc63", "choice_type": "single"} {"question": "Most common nodule found in the liver is", "exp": "Hemangioma Most common benign tumor of the liver Mainly seen in women of 45 years Small capillary hemangiomas(no clinical significance), larger cavernous hemangioma Usually single and <5 cm in diameter, occur equally in right and left liver Giant hemangioma: lesion>5cm Ref:Sabiston 20th edition Pgno :1456-1457", "cop": 3, "opa": "Hepatoma", "opb": "Haraoma", "opc": "Hemangioma", "opd": "Cholangiodenoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "722e9f73-024d-4670-8a9e-0d0d3481c90e", "choice_type": "single"} {"question": "Not a muscle of the tongue", "exp": "Intrinsic muscles of the tongue: \n\nMuscles found entirely within the tongue\nLongitudinal, transverse, and vertical muscles\nFunction - change the shape of the tongue.\n\nExtrinsic muscles of the tongue:\n\nGenioglossus, Styloglossus, and hyoglossus, Palatoglosus.\nAll insert into the tongue, originate from surrounding structures", "cop": 2, "opa": "Genioglossus", "opb": "Sternohyoid", "opc": "Hyoglossus", "opd": "Styloglossus", "subject_name": "Anatomy", "topic_name": null, "id": "4db9be47-a34c-42e7-8b3b-80459494c8a0", "choice_type": "single"} {"question": "Perscualr lymphocytes and microglial nodules are seen in", "exp": "Refer Robbins page no Pg 1278 HIV encephalitis is best characterized by microscopically as a chronic inflammatory reaction with widely distributed infiltrates of microglial nodules", "cop": 4, "opa": "Multiple sclerosis", "opb": "CMV meningitis", "opc": "Bacterial meningitis", "opd": "HIV encephalitis", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "9fc61a86-c863-4c1f-9487-0f94da656069", "choice_type": "single"} {"question": "Drug of choice for pneumocystis carinii is", "exp": "The treatment of choice for PCP is trimethoprim-sulfamethoxazole (TMP-SMX), given either IV or PO for 14-21 days .TMP-SMX, which interferes with the organism's folate metabolism, is at least as effective as alternative agents and is better tolerated. Ref Harrison 19th edition pg 1019 Davidson edition23rd pg 587", "cop": 2, "opa": "Doxycycline", "opb": "Cotrimoxazole", "opc": "Tetracycline", "opd": "Dapsone", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "241321e8-8b27-48b6-b698-a31de0e5e943", "choice_type": "single"} {"question": "Hutchinsons secondaries In skull are due to tumors in", "exp": "Adrenal neuroblastomas are malig8nant neoplasms arising from sympathetic neuroblsts in Medulla of adrenal gland Neuroblastoma is a cancer that develops from immature nerve cells found in several areas of the body.Neuroblastoma most commonly arises in and around the adrenalglands, which have similar origins to nerve cells and sit atop the kidneys.", "cop": 3, "opa": "Lung", "opb": "Breast", "opc": "Adrenal", "opd": "Liver", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "9409edf0-7977-4824-ad70-2172bef513f5", "choice_type": "single"} {"question": "Formation of primary ovary in female foetus takes place by", "exp": "C i.e. 10 weeks", "cop": 3, "opa": "6th week", "opb": "8th week", "opc": "10th week", "opd": "12th week", "subject_name": "Anatomy", "topic_name": null, "id": "793539d2-5e54-40ad-9804-5b494078afd6", "choice_type": "single"} {"question": "Muscle not inseed on the greater tuberosity is", "exp": "The supraspinatus, infraspinatus, teres minor and subscapularis muscles comprise the rotator cuff muscle group. The main role of these muscles is stabilization of the humeral head in the glenoid fossa. Tendons of teres minor, supraspinatus, and infraspinatus inse on the greater tuberosity of the humerus, and subscapularis tendon inses on lesser humeral tuberosity. Actions of these muscles are internal rotation (subscapularis), external rotation (teres minor and infraspinatus) and early abduction from 0@ to 30@ (supraspinatus). The subacromial bursa lies between supraspinatus tendon and the acromion.", "cop": 4, "opa": "Teres minor", "opb": "Supraspinatus", "opc": "Infraspinatus", "opd": "Subscapularis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "8d8202d8-57f8-4c7e-bd9e-6d3926cbbd23", "choice_type": "single"} {"question": "In stable angina", "exp": "Ref Harrison 19 th ed pg 1593 Necrotic myocardial fibres release a variety of enzymes into blood stream. In stable angina necrosis of the cell does not occur so there is no elevation of serum enzymes.", "cop": 4, "opa": "CK- MB is elevated", "opb": "Troponin 1 is elevated", "opc": "Myoglobin is elevated", "opd": "The level of cardiac markers remain un changed", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7f502498-282d-4167-8f9a-f2523880d1d7", "choice_type": "single"} {"question": "Gartner's duct is remnant of", "exp": null, "cop": 2, "opa": "Miillerian duct", "opb": "Wolffian duct", "opc": "Cloacal duct", "opd": "Epoo phoron", "subject_name": "Anatomy", "topic_name": null, "id": "ef68a6c9-37bd-43eb-bf6a-1da5250fffce", "choice_type": "single"} {"question": "Meckel&;s diveiculum is a remnant of", "exp": "A Meckel's Diveiculum is a vestigial remnant of omphalomesenteric or vitellointestinal duct. As a congenital anomaly, it is a true diveiculum that includes all three coat of small intestine. ref - BDC 6e vol2 pg 265", "cop": 4, "opa": "Stenson's duct", "opb": "Wolffian duct", "opc": "Mullerian duct", "opd": "Vitellointestinal duct", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "28259789-388a-4bdf-bbe5-8b11fb66bb23", "choice_type": "single"} {"question": "Chronic osteomyelitis is diagnosed mainly by", "exp": "* SEQUESTRUM -- is a piece of dead bone , surrounded by infected granulation tissue trying to \"eat\" the sequestrum away. It appears pale having smooth inner surface and a rough outer. * When SEQUESTRUM IS COMPLETE, it lies in the free cavity and is LESS attacked by granulation tissue and is absorbed more slowly. * Meanwhile , the surrounding living bone attempts to wall off the infection by forming a thick , dense wall , the INVOLUCRUM. * (INVOLUCRUM is the dense sclerotic bone overlying the sequestrum). * An involucrum usually has multiple openings, the cloacae , through which exudate , bone debris , and sequestra find exit and pass through sinus tracts to the surface. * CONSTANT DESTRUCTION of neighboring soft tissue leads to THIN skin which is easily traumatised , skin epithelium grows inwards to line the sinus tract. * In chronic osteomyelitis of long standing , multiple cavities and sequestra exist throughout the bone * The shaft becomes thickened , irregular and deformed. ref : maheswari 9th ed", "cop": 1, "opa": "Sequestrum", "opb": "Bone fracture", "opc": "Deformity", "opd": "Brodie's abscess", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "f477051e-a17a-4ca6-8d14-c768dad1699d", "choice_type": "single"} {"question": "Vaginal epithelium develops from", "exp": "Vagina develops from merodum of parameronephric duct endodum of urogenital ridge.", "cop": 3, "opa": "Meroderm of urogenital sinus", "opb": "Meroderm of genital ridge", "opc": "Endoderm of urogenital ridge", "opd": "Endoderm of genital ridge", "subject_name": "Anatomy", "topic_name": null, "id": "4364ee93-68bb-4c31-b211-f60edb36dd11", "choice_type": "single"} {"question": "Dose response curves of salbutamol for bronchodilation and tachycardia are widely separated on dose axis. This information suggested that sulbutamol is", "exp": "Ref-Katzung 10/e p28,29 Wide Separation of two curves on DRC suggest that the dose required to produce one action is much higher than the other.", "cop": 4, "opa": "Highly potent cardiac stimulant", "opb": "Highly efficacious bronchodilator", "opc": "Highly toxic drug", "opd": "Highly selective drug", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "666ef1b9-7df2-4d06-ab87-60ef947f3910", "choice_type": "single"} {"question": "Sister marry Joseph nodules are found in", "exp": "Refer Robbins page no Pg 8th/786 In medicine, the Sister Mary Joseph nodule or more commonly node, also called Sister Mary Joseph sign, refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen", "cop": 1, "opa": "Gastric carcinoma", "opb": "Pancreatic carcinoma", "opc": "Lung carcinoma", "opd": "Ovary carcinoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "639a4a5c-377c-4dad-8544-25e0957ab76e", "choice_type": "single"} {"question": "Action of 20mcg/kg/min dopamine is", "exp": "Less than 2mcg/kg/min: Renal VD 2-10mcg/kg/min: B1 stimulation More than 10: alpha stimulation -VC", "cop": 2, "opa": "Renal vasodilatation", "opb": "Vasoconstriction", "opc": "Increased blood pressure", "opd": "Increased myocardiac contractility", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94d670b9-1b9b-4307-a8cc-580d475adc0c", "choice_type": "single"} {"question": "The direction of the flow of venous blood in conditions of valve incompetence affecting perforating veins of lower limb is", "exp": "PERFORATING VEINS:- Connect superficial with the deep veins. Small saphenous vein -1 perforator. Great saphenous vein perforators:- 3 medial perforators-just above ankle.1 perforator just below knee 1 in the region of adductor canal. These contain valves to prevent backflow of venous blood .i.e prevent flow from deep to superficial. Incompetence of these valves makes vein dilated and touous leading to varicose veins. If the valves in the perforating veins or at the termination of superficial veins become incompetent, the defective veins become \"high-pressure leaks\" through which high pressure of deep veins produced by muscular contractions is transmitted to superficial veins. This results in dilatation of superficial veins and to gradual degeneration of their walls producing varicose veins and varicose ulcers {Reference: BDC 9 E}", "cop": 4, "opa": "Along gravity", "opb": "Superficial to deep", "opc": "Along osmotic gradient", "opd": "Deep to superficial", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "311cb417-a8f5-40d9-818b-46803a5fd9e0", "choice_type": "single"} {"question": "Absolute lymphocytosis is seen in", "exp": "ref to P.JMehta 14/e p374 CLL and brucellosis is also the answer Leukocytosis is white cells (the leukocyte count) above the normal range in the blood. It is frequently a sign of an inflammatory response, most commonly the result of infection, but may also occur following ceain parasitic infections or bone tumors as well as leukemia", "cop": 2, "opa": "SLE", "opb": "TB", "opc": "CLL", "opd": "Brucellosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "323e05b8-80d7-40e9-88e2-555819baeb8a", "choice_type": "single"} {"question": "3rd Ventricle develops from", "exp": "Inderbir Singh&;sHuman embryologyTenth editionPg 335The cavity of diencephalon forms the third ventricle", "cop": 1, "opa": "Diencephalon", "opb": "Telencephalon", "opc": "Mesencephalon", "opd": "Prosencephalon", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6e847e0c-bd12-48ad-9e61-2dcdbfe1db47", "choice_type": "single"} {"question": "Major Disadvantage of peripheral line is", "exp": "Ref: Bailey and love 27th edition Pg no :287", "cop": 4, "opa": "Catheter related sepsis", "opb": "Damage to adjacent aery", "opc": "Refeeding syndrome", "opd": "Thrombophlebitis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fdcc3d9b-5a62-4bb6-86aa-053d4fa7dcbe", "choice_type": "single"} {"question": "Secondary amyloidosis is associated with", "exp": "Ref Robbins 8/e p252-253,9/e p257 The AA (amyloid-associated) fibril is a unique nonim- munoglobulin protein derived from a larger (12-kDa)serum precursor called SAA (serum amyloid-associated) protein that is synthesized in the liver. SAA is synthesized by liver cells under the influence of cytokines such as IL-6 and IL-1 that are produced during inflammation; thus, long-standing inflammation leads to elevated SAA levels, and ultimately the AA form of amyloid deposits. However, increased production of SAA by itself is not sufficient for the deposition of amyloid. Elevation of serum SAA levels is common to inflammatory states but in most instances does not lead to amyloidosis. There are two possible explanations for this. According to one view, SAA nor- mally is degraded to soluble end products by the action of monocyte-derived enzymes. Conceivably, people who develop amyloidosis have an enzyme defect that results in incomplete breakdown of SAA, thus generating insoluble AA molecules. Alternatively, a genetically determined structural abnormality in the SAA molecule itself renders it resistant to degradation by macrophages", "cop": 3, "opa": "A beta", "opb": "AL", "opc": "AA", "opd": "APrP", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "98c44966-1d3f-49b9-8e0e-4a7cf9240c84", "choice_type": "single"} {"question": "Glossopharyngeal nerve supply", "exp": null, "cop": 1, "opa": "Stylopharyngeus muscle", "opb": "Palatopharyngeus", "opc": "Salpingopharyngeus", "opd": "Constrictors of pharynx", "subject_name": "Anatomy", "topic_name": null, "id": "5cf1137a-4adc-4ed2-85fe-d924eeef4ed5", "choice_type": "single"} {"question": "Most common complication of common bile duct exploration", "exp": "Most common complication of CBD exploration is retained stone Clearance of all common bile duct stones is achieved in 75-95% of patients with laparoscopic CBD exploration The rate of retained CBD stone is <5% Ref: Sabiston 20th edition Pgno :1496", "cop": 1, "opa": "Retained stone", "opb": "Pancreatitis", "opc": "Stricture of CBD", "opd": "T-tube displacement", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "074e4e84-1d24-4840-ab96-867240b8e0cb", "choice_type": "single"} {"question": "Erb's point is", "exp": "B. i.e. Anterior primary rami of C5- C6", "cop": 2, "opa": "Posterior primary rami of C6-C7", "opb": "Anterior primary rami of C5-C6", "opc": "Posterior primary rami of Cs-T1", "opd": "Posterior primary rami of C2-C8", "subject_name": "Anatomy", "topic_name": null, "id": "34fa3220-e988-48b1-9bb1-9f8964a59d16", "choice_type": "single"} {"question": "If the origin of the masseter muscle is more medial on the zygomatic arch (ramus perpendicular), the space in the distobuccal area is", "exp": null, "cop": 1, "opa": "Decreases", "opb": "Remains the same", "opc": "Increases then decreases", "opd": "Increases", "subject_name": "Anatomy", "topic_name": null, "id": "d0b6a7d9-3c3a-4b7c-a6de-fdbf8fb14cdf", "choice_type": "single"} {"question": "Broca’s area is located at", "exp": null, "cop": 3, "opa": "Superior frontal gyrus", "opb": "Inferior temporal gyrus", "opc": "Inferior frontal gyrus", "opd": "Superior temporal gyrus", "subject_name": "Anatomy", "topic_name": null, "id": "d833c046-7a7c-4858-b8d8-ce548f3171a6", "choice_type": "single"} {"question": "The structure that passes between middle cerebellar peduncle and pons is", "exp": "Trigeminal nerve exits the brain by a large sensory root and a smaller motor root coming out of the pons at its junction with the middle cerebellar peduncle.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg-81, fig 8.9)", "cop": 1, "opa": "Trigeminal nerve", "opb": "Vagus nerve", "opc": "Olfactory nerve", "opd": "Optic nerve", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "98c6fdb0-306a-4975-a5a6-43f9f6f9c163", "choice_type": "single"} {"question": "Number of primodial follicles in ovary at bih are", "exp": "At bih the number of login is(primordial follicles) in an ovary is about one millionSo for two ovaries, it is about 2 millionInderbir Singh&;s Human Histology Seventh edition Pg 346", "cop": 1, "opa": "2 million", "opb": "6 million", "opc": "5 million", "opd": "10 million", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5f8fcf17-fe32-4af2-86d8-5868a8012753", "choice_type": "single"} {"question": "Coical representation of body in cerebrum is", "exp": "B i.e. Veical", "cop": 2, "opa": "Horizontal", "opb": "Veical", "opc": "Tandem", "opd": "Oblique", "subject_name": "Anatomy", "topic_name": null, "id": "f1fa8d42-0b6d-4186-a6a2-b99bc1db895c", "choice_type": "single"} {"question": "maternal disomy of chromosomes 15 is seen in", "exp": "Prader Willi syndrome could be present because of the following ; Deletion of paternal chromosome 15 .Or Uniparentral disomy of maternal chromosome 15 refer robbins 8/172", "cop": 1, "opa": "A. Prader Willi syndrome", "opb": "B. Klinefelter syndrome", "opc": "C. Angelman syndrome", "opd": "D. Turner's syndrome", "subject_name": "Anatomy", "topic_name": "General pathology", "id": "53f5f95c-65fb-4a0d-bc33-ee8a09d758b0", "choice_type": "single"} {"question": "Action of inferior oblique", "exp": "The actions of inferior oblique are: At veical axis-elevates At horizontal axis-abducts At anteroposterior axis-extorsion Notes; The inferior oblique arises from the orbital surface of the maxilla, lateral to the lacrimal groove. This muscle is situated near the anterior margin of the orbit. Ref BDC volume3.sixth edition pg 211", "cop": 3, "opa": "Adduction", "opb": "Depression", "opc": "Extorsion", "opd": "Intorsion", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b0289d17-991e-4119-9c8c-cb04f9ed418a", "choice_type": "single"} {"question": "Structure passing through esophageal opening of diaphragm", "exp": "Oesophageal opening transmits gastric or vagus nerves. B D CHAURASIA&;S HUMAN ANATOMY LOWER LIMB ABDOMEN AND PELVIS VOLUME-2,SIXTH EDITION Page no-333", "cop": 3, "opa": "Right phrenic nerve", "opb": "Azygous vein", "opc": "Gastric nerves", "opd": "Thoracic duct", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "4c9e233f-b55f-48e2-92ca-6df1efa250f9", "choice_type": "single"} {"question": "Vestibular ocular reflex", "exp": null, "cop": 4, "opa": "Neo Cerebellum", "opb": "Occipital Lobe", "opc": "Paleocerebellum", "opd": "Flocculonodular Lobe", "subject_name": "Anatomy", "topic_name": null, "id": "f7ecdfee-f52d-4485-b1d5-01bbadeb16b2", "choice_type": "single"} {"question": "Most impoant for diapedisis", "exp": "Ref Robbins 8/e p50;9/e p77 Leukocytes normally flow rapidly in the blood, and in inflamma- tion, they have to be stopped and brought to the offending agent or the site of tissue damage, which are typically outside the vessels. The sequence of events in the recruitment of leuko- cytes from the vascular lumen to the extravascular space consists of (1) margination and rolling along the vessel wall; (2) firm adhesion to the endothelium; (3) transmigra- tion between endothelial cells; and (4) migration in inter- stitial tissues toward a chemotactic stimulus (Fig. 2-5). Rolling, adhesion, and transmigration are mediated by the interactions of adhesion molecules on leukocytes and endothelial surfaces (see later on). Chemical mediators-- chemoattractants and ceain cytokines--affect these pro- cesses by modulating the surface expression and binding affinity of the adhesion molecules and by stimulating direc- tional movement of the leukocytes. Margination and Rolling. As blood flows from capillaries into postcapillary venules, circulating cells are swept by laminar flow against the vessel wall. Because the smaller red cells tend to move faster than the larger white cells, leukocytes are pushed out of the central axial column and thus have a better oppounity to interact with lining endothelial cells, especially as stasis sets in. This process of leukocyte accumulation at the periphery of vessels is called margination. If the endothelial cells are activated by cytokines and other mediators produced locally, they express adhesion molecules to which the leukocytes attach loosely. These cells bind and detach and thus begin to tumble on the endothelial surface, a process called rolling. Adhesion. The rolling leukocytes are able to sense changes in the endothelium that initiate the next step in the reaction of leukocytes, which is firm adhesion to endothelial sur- faces. This adhesion is mediated by integrins expressed on leukocyte cell surfaces interacting with their ligands on endothelial cells", "cop": 1, "opa": "PECAM", "opb": "Selectins", "opc": "Integrins", "opd": "Mucin like glycoprotein", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e972f5c9-cb3a-4de1-8fbe-4c4776f15f88", "choice_type": "single"} {"question": "The initiating mechanism in endotoxic shock is", "exp": "ref Robbins 9/e p131-132 The principal mechanism for septic shock includes: Peripheral vasodilation and pooling of blood Endothelial activation/injury Leukocyte induced injury Disseminated intravascular coagulation Activation of cytokine cascades", "cop": 2, "opa": "Peripheral vasodilation", "opb": "Endothelial injury", "opc": "Increased vascular permeability", "opd": "Reduced cardiac output", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ffeb8935-4bdb-42c1-b109-e8c241dbdc10", "choice_type": "single"} {"question": "Thyroid gland develops from", "exp": null, "cop": 1, "opa": "Thyroglossal duct", "opb": "Rathke's pouch", "opc": "Notochordal process", "opd": "Embryonal disc", "subject_name": "Anatomy", "topic_name": null, "id": "f5cd6ac5-3968-4781-be6a-2c26b340e50f", "choice_type": "single"} {"question": "Iliofemoral ligament arises from", "exp": "SSIliofemoral Ligament is also called Ligament of Bigelow.SSStrongest ligament in the body.SSInveed Y shaped, strengthens the anterior pa of capsule of HIP JOINTThe upper half of the anterior inferior iliac spine gives origin to the straight head of the rectus femoris. The rough lower pa of this spine gives attachment to the iliofemoral ligamentReference: Chaurasia; 6th edition; Chapter 2; Bones of the lower limb", "cop": 3, "opa": "Ischial tuberosity", "opb": "Anterior superior iliac spine", "opc": "Anterior inferior iliac spine", "opd": "Iliopubic rami", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "6b6bdd5f-5492-442e-9632-c5d8a1409de3", "choice_type": "single"} {"question": "A 45 year old lady is having persistent reflux symptoms. Most accurate investigation in establishing the diagnosis before surgical treatment is", "exp": "GERDGERD is often associated with hiatus hernia type IClinical featuresInvestigationsClassical traid: retrosternal burning pain, epigastric pain, and regurgitation.HeaburnsRegurgitationAbdominal painCoughDysphagia for solidsBelchingBloatingManometry for measuring LES tone24 hrs pH monitoringEsophagogram TreatmentLifestyle modifications: cessation of smoking, decreased caffeine intake and avoidance of large meal at nightMedical management: double dose of PPI'SSurgical therapy: laparoscopic Nissen's fundoplication, modern fundoplication, 3600 floppy fundoplication (Refer: Sabiston's Textbook of Surgery, 19th edition, pg no: 1081)", "cop": 4, "opa": "An UGI series", "opb": "Endoscopy", "opc": "Esophageal manometry", "opd": "24 hours pH monitoring", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1332ada1-35f2-4605-9613-489d21690563", "choice_type": "single"} {"question": "Nutrient aery arises to fibula from", "exp": "Nutrient aery to fibula:- The peroneal aery gives off nutrient aery to fibula.Enters the bone on its posterior surface.Nutrient foramen directed downwards. {Reference: BDC 6E}", "cop": 1, "opa": "Peroneal aery", "opb": "Anterior tibial aery", "opc": "Posterior tibial aery", "opd": "Popliteal aery", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e50a2405-b97d-4553-84d0-c3f964e96f64", "choice_type": "single"} {"question": "3. Drug used in the Pseudomonas treatment", "exp": "Psedomonas is inherently resistant to most of the antibiotics. Cephalosporins such as ceftazidime ,cefoperazone, ceftolozane and cefepime are used to treat it", "cop": 2, "opa": "Cefixime", "opb": "Ceftazidime", "opc": "Ampicillin", "opd": "Cotrimoxazole", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "f89fdba6-62bb-46fd-bda5-af610b529256", "choice_type": "single"} {"question": "Most common tumor of infancy is", "exp": "Refer robbins 8/e p584 A rhabdomyoma is a benign tumor of striated muscle. Rhabdomyomas may be either \"cardiac\" or \"extra cardiac\" (occurring outside the hea). Extracardiac forms of rhabdomyoma are sub classified into three distinct types: adult type, fetal type, and genital type. Cardiac rhabdomyomas are the most common primary tumor of the hea in infants and children. It has an association with tuberous sclerosis. In those with tuberous sclerosis, the tumor may regress and disappear completely, or remain consistent in size. It is most commonly associated with the tongue, and hea, but can also occur in other locations, such as the vagina. Malignant skeletal muscle tumors are referred to as rhabdomyosarcoma. Only rare cases of possible malignant change have been repoed in fetal rhabdomyoma. The differential diagnosis in the tongue includes ectomesenchymal chondromyxoid tumor.", "cop": 2, "opa": "Lymphangioma", "opb": "Rhabdomyoma", "opc": "Hemangioma", "opd": "Lipoma", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "2bfb92b7-fc20-430d-a84c-cf3e03aa9b41", "choice_type": "single"} {"question": "Epithelium lining of lingual surface of epiglottis is", "exp": "Stratified squamous epithelium is present in pharynx, lingual surface of epiglottis which is non keratinised in nature whereas in laryngeal surface of epiglottis it is lined by pseudostratified ciliated columnar epithelium (respiratory epithelium).", "cop": 4, "opa": "Simple Columnar", "opb": "Pseudostratified ciliated columnar", "opc": "Simple Cuboidal", "opd": "Stratified squamous epithelium", "subject_name": "Anatomy", "topic_name": "Epithelial tissue", "id": "4673ea7f-a76d-4d92-8d3c-1b8a4bc6a4d7", "choice_type": "single"} {"question": "Cox pathway is not inhibited by", "exp": "Aspirin inhibits Cox irreversibly by acetylating one of its serine residues;return of Cox activity depends are depends on synthesis of freshers I enzymes. other NSAIDs like indomethacin, diclofenac, etc are competative and Irreversible inhibitors of Cox, return of activity depends upon the dissociation from enzyme which in turn is governed by pharmacokinetic characteristics of its compound coicosteroids like betamethasone act by inhibiting phospholipase A2.", "cop": 3, "opa": "Aspirin", "opb": "Indomethacin", "opc": "Betamethasone", "opd": "Diclofenac", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7fb7bf64-10a3-4b27-8792-2c4330b370d8", "choice_type": "single"} {"question": "Facial artery is a branch of", "exp": "The facial artery is the chief artery of the face. It is a branch of the external carotid artery .", "cop": 1, "opa": "External carotid artery", "opb": "Internal carotid artery", "opc": "Transverse facial artery", "opd": "Buccal artery", "subject_name": "Anatomy", "topic_name": null, "id": "4c91cc30-aec4-4e5e-845e-d50bff6230c6", "choice_type": "single"} {"question": "Pyramidalis is supplied by", "exp": "The pyramidalis is a small and triangular muscle, anterior to the rectus abdominis, and contained in the rectus sheath. The muscle is innervated by the ventral poion of T12. Anterior division of the twelfth thoracic nerve (subcostal nerve) communicates with the iliohypogastric nerve of the lumbar plexus and gives a branch to the Pyramidalis. Ref - semantischolar.org", "cop": 1, "opa": "Subcostal nerve", "opb": "Ilioinguinal nerve", "opc": "Iliohypogastric nerve", "opd": "Genitofemoral nerve", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "3476eb4f-9159-443e-a186-468a303e9bc9", "choice_type": "single"} {"question": "The remnant of an omphalomesenteric duct is", "exp": "The omphalomesenteric duct is an embryonic structure which connects the yolk sac to the midgut, it gets obliterated between the 5thand 9th week of gestation, failure of which result in remnants like Meckel's diveiculum or cyst or fistula The median umbilical ligament is a remnant of the urachus The medial umbilical ligaments are a remnant of the umbilical aeries Ref: Gray's 39e/p-1289", "cop": 2, "opa": "Median umbilical ligament", "opb": "Meckel's diveiculum", "opc": "Median umbilical fold", "opd": "Omphalocele", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bd75b124-32fe-44b7-8bb9-8447ffeba0ed", "choice_type": "single"} {"question": "Thyroid Ca causes laryngeal paralysis due to", "exp": "The nerves found in close relationship to the thyroid gland and therefore likely to be involved in the malignant spread and thyroid surgery are recurrent laryngeal nerve and the superior laryngeal nerve. Ref : Schwaz Surgery 9/e p1346", "cop": 1, "opa": "Recurrent laryngeal nerve palsy", "opb": "Vagus nerve palsy", "opc": "Glossopharyngeal nerve palsy", "opd": "Hypoglossal nerve palsy", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "65f581f9-72de-417c-919f-a400a96a8ffe", "choice_type": "single"} {"question": "Extension of knee joint is caused by", "exp": "C. i.e. Quadriceps femoris", "cop": 3, "opa": "Gracilis", "opb": "Popliteus", "opc": "Quadriceps femoris", "opd": "Semitendinosus", "subject_name": "Anatomy", "topic_name": null, "id": "55eda9a9-48cf-42af-a6ce-61d65dcaa0f8", "choice_type": "single"} {"question": "Most dependent pa of abdomen in standing position is", "exp": "The recto-uterine pouch (cul-de-sac or pouch of Douglas) is the extension of the peritoneal cavity between the rectum and the posterior wall of the uterus. It is the most inferior aspect of the peritoneal cavity and therefore the first location where free fluid accumulates . ref - BDC 6e vol2 pg244", "cop": 2, "opa": "Vesicouterine pouch", "opb": "Pouch of douglas", "opc": "Morrison pouch", "opd": "Left paracolic gutter", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "3160f04e-7284-41bc-a561-dd467e9a23c7", "choice_type": "single"} {"question": "Reduced liver transplants", "exp": "Reduced size liver transplant Liver can be reduced to a functional unit of appropriate size for the recepient It can overcome the donor - recepient size discrepancy, but it does not increase the absolute number of grafts Ref: Sabiston 20th edition Pgno : 637-638", "cop": 4, "opa": "Given to two recepients after dividing into two pas", "opb": "Left lateral lobe divided and given to child", "opc": "Left lateral segment divided from segment 2 and gives to child", "opd": "Pa of liver segment transplanted into recepient depending upon requirement", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "bb7052f8-235b-4de7-b8a1-41cc23233e0c", "choice_type": "single"} {"question": "The simple columnar and stratified columnar epithelia lining the lower pa of the anal canal is derived from", "exp": "The anal canal is formed from two components--the hindgut and proctodeum. The epithelium lining the lower anal canal is derived from ectoderm lining the proctodeum. above the pectinate line develop from:-endodermal cloacae beiow the pectinate line delelop from :-ectodermal proctodeum", "cop": 3, "opa": "Mesoderm", "opb": "Endoderm", "opc": "Ectoderm", "opd": "Neuroectoderm", "subject_name": "Anatomy", "topic_name": "Embryology and abdominal wall layer", "id": "bb0c9fd8-0e1b-4ccf-8187-5e64e391117e", "choice_type": "single"} {"question": "Radial bursa is the synol sheath covering the tendon of", "exp": "The radial Bursa is a collection of synol fluid around the Tendon of the Flexor Pollicis Longus muscle, the primary flexor of the thumb ulnar bursa is a synol sheath in the carpal tunnel of the human hand. It contains tendons of the flexor digitorum an and the flexor digitorum profundus", "cop": 3, "opa": "Flexor digitorum superficialis", "opb": "Flexor digitorum profundus", "opc": "Flexor Pollicis Longus", "opd": "Flexor carpi radialis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "f6e1ae37-b35f-4123-9c81-1aca891d8eda", "choice_type": "single"} {"question": "Excessive bleeding during hemothorax is caused by", "exp": "Massive Hemothorax: Collection of more than 1500 ml of blood in the pleural cavity is called massive hemothorax. Massive hemothorax is usually the result of major pulmonary vascular injuries or major aerial wounds, while minor lung injuries cause small hemothorax. Also know Most common cause of hemothorax is due to injuries of Internal mammary Aery. Ref : Sabiston 18/e p498", "cop": 4, "opa": "Venacava", "opb": "Hea", "opc": "Internal mammary aery", "opd": "Major aery", "subject_name": "Anatomy", "topic_name": "Cardio thoracic surgery ", "id": "23a935b3-8da4-4cd2-b019-35ff085d898c", "choice_type": "single"} {"question": "The components of Levator ani are", "exp": "Pubococoygeus & lliococcygeus together is known as Levator ani", "cop": 2, "opa": "Pubococoygeus, Ischiococcygeus", "opb": "Pubococoygeus, lliococcygeus", "opc": "Pubococoygeus, Iliococcygeus & Ischiococcygeus", "opd": "Ischiococcygeus, lliococcygeus", "subject_name": "Anatomy", "topic_name": null, "id": "2a3f15ed-a752-48c4-8ec5-a37b380f24a6", "choice_type": "single"} {"question": "Sacral ala is related to", "exp": "Ans. is 'd' i.e., Iliolumbar aery,Ala of sacrum is a large triangular surface either side of sacral base, continuous with iliac fossa (akin to adapted and joined transverse and costal processes elsewhere spine)The smooth medial pa of the ala of sacrum is associated with the subsequent 4 structures from medial to lateral side: 1. Sympathetic chain. 2. Lumbosacral trunk. 3. Iliolumbar aery. 4. Obturator nerve.The ventral ramus of L5 nerve is really tight that it grooves the ala.The rough lateral pa of the ala provides origin to iliacus muscle anteriorly and connection to the lumbosacral ligament posteriorly.", "cop": 4, "opa": "Ureter", "opb": "Parasympathetic ganglion", "opc": "Umbilical aery", "opd": "Iliolumbar aery", "subject_name": "Anatomy", "topic_name": null, "id": "90970ecc-69aa-445e-a590-79f6e7fa06b9", "choice_type": "single"} {"question": "Primary and secondary palates are divided by", "exp": "D. i.e. Incisive foramenThe incisive foramen is dividing landmark between the primary & secondary palateQ; and anterior & posterior cleft deformities", "cop": 4, "opa": "Greater palatine foramen", "opb": "Canine teeth", "opc": "Alveolar arch", "opd": "Incisive foramen", "subject_name": "Anatomy", "topic_name": null, "id": "966dd816-88a5-41eb-945f-2dc2e2b55a20", "choice_type": "single"} {"question": "The primary palate is formed from the", "exp": "The primary palate develops from the intermaxillary segment that is formed by the fusion of two medial nasal prominences. The two medial nasal prominences fuse to form the intermaxillary segment, which has the following components: Labial component that forms the philtrum of the upper lip Upper jaw component that forms the medial pa of the maxillary bone with the four upper incisor teeth Palatal component that forms the triangular area in the front called as the primary palate. Ref: Inderbir Singh Human Embryology 11e pg 160.", "cop": 1, "opa": "Medial nasal prominences", "opb": "Lateral nasal prominences", "opc": "Maxillary prominences", "opd": "Mandibular prominences", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "990d5004-00ee-4da3-9010-2dce40358964", "choice_type": "single"} {"question": "Dura Mater derives its name from", "exp": "(D) Tough mother # Dura mater, or dura, is the outermost of the three layers of the meninges surrounding the brain and spinal cord.> It is derived from Mesoderm.> Other two meningeal layers are the pia mater and the arachnoid mater.> Dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid.> Name \"dura mater\" is derived from the Latin \"hard mother\" or \"tough mother\", and is also referred to by the term \"pachy-meninx\".", "cop": 4, "opa": "Leather like appearance", "opb": "Double layered mother", "opc": "Tender mother", "opd": "Tough mother", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "7283e258-e90f-4b23-ba21-245c31f0b4d7", "choice_type": "single"} {"question": "Child's criteria is used in Cirrhosis", "exp": "Variables of CTP score Serum albumin Serum bilirubin Prothrombin time Ascites Encephalopathy Ref: Sabiston 20th edition Pgno : 1436", "cop": 2, "opa": "Pancreatitis", "opb": "Cirrhosis", "opc": "Multiple myeloma", "opd": "AIDS", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "3b444ed8-9ded-498f-8578-63e032a75d45", "choice_type": "single"} {"question": "Efferent cremastric reflex is carried by", "exp": "Ans. (b) Genito-femoral nerveRef: Clinically Oriented Anatomy by Keith, Moore, 5thEd,/223# CREMASTERIC REFLEXEfferent: genital branch of genitofemoral nerveAfferent: Femoral branch of genitofemoral nerve* Contraction of the cremaster muscle is elicited by lightly stroking the skin on the medial aspect of the superior part of the thigh with an applicator stick or tongue depressor.* The ilioinguinal nerve supplies this area of skin.The rapid elevation of the testis on the same side is the cremasteric reflex. This reflex is extremely active in children* A hyperactive cremasteric reflex may simulate undescended testes.", "cop": 2, "opa": "Illio inguinal nerve", "opb": "Genito-femoral nerve", "opc": "Iliohypogastric nerve", "opd": "Pudendal nerve", "subject_name": "Anatomy", "topic_name": "Nerves of Lower Extremity", "id": "46f82405-0a3e-4ae8-a640-bebe08f331b5", "choice_type": "single"} {"question": "Unilateral supranuclear lesion of facial nerve involves", "exp": null, "cop": 3, "opa": "Whole of face", "opb": "Only ipsilateral upper part of the face", "opc": "Only contra lateral lower part of the face", "opd": "Whole of lower face", "subject_name": "Anatomy", "topic_name": null, "id": "40330351-90f6-48ef-90f9-c196d403b967", "choice_type": "single"} {"question": "Fastest acting receptor/transduction mechanism is", "exp": "Ref-KDT 6/e p40 Drugs acting and ionotropic receptor are fast acting where as those acting through nuclear receptors are slowest in action", "cop": 3, "opa": "Adenylyl cyclase-cyclic AMP pathway", "opb": "Phospholipase C-IP3:DAG pathway", "opc": "Intrinsic ion channel operation", "opd": "Nuclear receptor", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "f9761f0f-021c-4957-bcb3-78a142129d47", "choice_type": "single"} {"question": "Hoffbauer's cells are present in", "exp": null, "cop": 3, "opa": "Pituitary gland", "opb": "Parathyroid", "opc": "Placenta", "opd": "Pineal gland", "subject_name": "Anatomy", "topic_name": null, "id": "643a6440-e1e2-4c25-8725-f7ef36e63bdb", "choice_type": "single"} {"question": "Diagnostic procedure for postmenopausal bleeding", "exp": "Gold standard is hysteroscopic directed endometrial sampling. Next, best is endometrial aspiration as it gives a global endometrial sample by viue of suction. D and C and EB should never be done to diagnose the cause of postmenopausal bleeding. The most common cause overall is senile endometritis and the most common malignant cause is endometrial cancer", "cop": 2, "opa": "Endometrial aspiration", "opb": "Hysteroscopic guided biopsy", "opc": "Dilatation and curettage", "opd": "Ultrasound", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "667203da-b8b4-4abb-9572-7c47b1b26e3f", "choice_type": "single"} {"question": "Not a premalignant condition", "exp": "Ref Robbins 9/e p169 Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females. Affected individuals usually have delayed development of speech and language by age 2. Most males with fragile X syndrome have mild to moderate intellectual disability, while about one-third of affected females are intellectually disabled. Children with fragile X syndrome may also have anxiety and hyperactive behavior such as fidgeting or impulsive actions. They may have attention deficit disorder (ADD), which includes an impaired ability to maintain attention and difficulty focusing on specific tasks. About one-third of individuals with fragile X syndrome have features of fragile X syndrome. Most males and about half of females with fragile X syndrome have characteristic physical features that become more apparent with age. These features include a long and narrow face, large ears, a prominent jaw and forehead, unusually flexible fingers, flat feet, and in males, enlarged testicles (macroorchidism) after pubey. Fragile X syndrome is inherited in an X-linked dominant pattern. A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome), a mutation in the only copy of a gene in each cell causes the disorder. In most cases, males experience more severe symptoms of the disorder than females. In women, the FMR1 gene premutation on the X chromosome can expand to more than 200 CGG repeats in cells that develop into eggs. This means that women with the premutation have an increased risk of having a child with fragile X syndrome. By contrast, the premutation in men does not expand to more than 200 repeats as it is passed to the next generation. Men pass the premutation only to their daughters. Their sons receive a Y chromosome, which does not include the FMR1 gene.", "cop": 1, "opa": "Fragile X syndrome", "opb": "Down's syndrome", "opc": "Blount's syndrome", "opd": "Fanconi's syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "63fd0e82-fc1b-4661-bc68-df4114fed81a", "choice_type": "single"} {"question": "Following type of epithelium is present in", "exp": "The above picture represents non-keratinized stratified squamous epithelium.Numerous cell layers, the most superficial of which are squamous, characterize stratified squamous epithelium. The function of this type of tissue is protection.Examples of non-keratinized stratified squamous epithelium include corneal epithelium, lining mucosa of the oral cavity, oesophagus, anal canal, ectocervix, vagina, foreskin, and the internal poion of the lips. Moist areas don&;t need protection from desiccation and are therefore nonkeratinized.", "cop": 2, "opa": "Skin", "opb": "Oesophagus", "opc": "Ileum", "opd": "Alveolus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "e8b3c4fb-32e7-48d9-9d1c-11c8c29fea8d", "choice_type": "single"} {"question": "Best prognosis in CA GB is seen in", "exp": "Histological types in gallbladder Carcinoma Diffuse infiltrative :MC type Nodular or mass forming Papillary : Exhibits polypoid or cauliflower appearance and have best prognosis Adenocarcinoma : MC histological subtype of CA GB Ref: Sabiston 20th edition Pgno :1512-1514", "cop": 1, "opa": "Papillary", "opb": "Adenocarcinoma", "opc": "Squamous", "opd": "Melanoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e96fe0ba-1b84-4d97-93e3-73def80a6f04", "choice_type": "single"} {"question": "Anchovy sauce pus is a feature of", "exp": "Amoebic liver abscess Entamoeba histolytica is endemic in many pas of the world. It exists in vegetative form outside the body and is spread by the faecal-oral route. The most common presentation is with dysentery, but it may also present with an amoebic abscess, the common sites being paracaecal and in the liver. The amoebic cyst is ingested and develops into the trophozoite form in the colon, and then passes through the bowel wall and to the liver the poal blood. Diagnosis is by isolation of the parasite from the liver lesion or the stool and confirming its nature by microscopy. Often patients with clinical signs of an amoebic abscess will be treated empirically with metronidazole (400- 800mg t.d.s. for 7-10 days) and investigated fuher only if they do not respond. Resolution of the abscess can be monitired using ultrasound. Ref: Bailey and love 27th edition Pg no : 1169", "cop": 1, "opa": "Amoebic liver abscess", "opb": "Lung abscess", "opc": "Splenic abscess", "opd": "Pancreatic abscess", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "faa3cb71-b79e-4b1d-a2d1-b868b33f806c", "choice_type": "single"} {"question": "Joint between epiphysis and diaphysis of a long bone is a type of", "exp": "D. i.e. Synchondrosis", "cop": 4, "opa": "Plane Synol joint", "opb": "Fibrous joint", "opc": "Symphysis", "opd": "Synchondrosis", "subject_name": "Anatomy", "topic_name": null, "id": "bb9d0a2f-28b5-4024-ba41-245a3371d797", "choice_type": "single"} {"question": "Deep flexors of forearm are supplied by", "exp": "Deep flexors of forearm are Flexor digitorum profundus, Flexor pollicis longus, and Pronator quadratus. Flexor digitorum medial half is supplied by Ulnar nerve and lateral half is supplied by the anterior interosseous nerve. Flexor pollicis longus and pronator quadratus are supplied by anterior interosseous nerve. REF:B D Chaurasia edition 7th page no:110.", "cop": 2, "opa": "Median nerve", "opb": "Ulnar nerve", "opc": "Radial nerve", "opd": "Musculocutaneous nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a8eb9afd-0ba8-4a07-9156-205ffba6808a", "choice_type": "single"} {"question": "Cytokines", "exp": "Ref ananthanarayana 7/e p143; Harrison 16/e p 1915; Robbins 7/e p202 Cytokines are a broad and loose category of small proteins (~5-20 kDa) that are impoant in cell signaling. Cytokines are peptides, and cannot cross the lipid bilayer of cells to enter the cytoplasm. Cytokines have been shown to be involved in autocrine signaling, paracrine signaling and endocrine s as immunomodulating agents The four-a-helix bundle family: member cytokines have three-dimensional structures with four bundles of a-helices. This family, in turn, is divided into three sub-families: the IL-2 subfamily the interferon (IFN) subfamily the IL-10 subfamily.", "cop": 1, "opa": "Includes interleukins", "opb": "Produced only insepsis", "opc": "Are polypeptide s", "opd": "Have highly specific action", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "09157e84-f78b-4f83-9b51-51f1be4e094d", "choice_type": "single"} {"question": "Main Aerial supply of the tonsil is from", "exp": "Facial aery supplies face, tonsil Ref: Gray's 40e/p-262", "cop": 1, "opa": "Facial aery", "opb": "Ascending pharyngeal aery", "opc": "Palatine aery", "opd": "Maxillary aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "459a26c5-26f5-476c-90d4-14f585f83c57", "choice_type": "single"} {"question": "Light microscopic characteristic features of apoptosis is", "exp": "Ref, Robbins 8/ep41-15,26-27,9/ep53", "cop": 4, "opa": "Intact cell membrane", "opb": "Eosinophilic cytoplasm", "opc": "Nuclear moulding", "opd": "Condensation of the nucleus", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dbcf6367-b512-4df2-a95e-424b522bc4b8", "choice_type": "single"} {"question": "Maximum risk of pancreatitis is present with", "exp": "All NIs can cause pancreatitis and peripheral neuropathy Maximum risk of pancreatitis is associated with dilation didanosine and maximum incidence of peripheral neuropathy is seen with stavudine Lamivudine is safest NI as has minimum risk of pancreatitis and peripheral neuropathy Refer Katzung 11/e p858", "cop": 1, "opa": "Didanosine", "opb": "Lamivudine", "opc": "Zidovudine", "opd": "Abacavir", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8ee119e1-9b21-49fc-9422-34e84d0f0c12", "choice_type": "single"} {"question": "The lymphatics from the median part of the forehead drains to", "exp": null, "cop": 1, "opa": "Submandibular nodes", "opb": "Submental nodes", "opc": "Preauricular parotid nodes", "opd": "Upper deep cervical nodes", "subject_name": "Anatomy", "topic_name": null, "id": "8510723f-feef-470a-baf2-b86b8826bc7d", "choice_type": "single"} {"question": "Not a tributary of Azygos Vein among the following is", "exp": "1. Formative tributaries of Azygos Vein are Lumbar Ascending vein, Subcostal Vein and lumbar azygos vein.\n2. Right Bronchial Vein is the last tributary of Azygos Vein", "cop": 3, "opa": "Lumbar Ascending vein", "opb": "Subcostal Vein", "opc": "Intercostolumbar azygos vein", "opd": "Right Bronchial Vein", "subject_name": "Anatomy", "topic_name": null, "id": "39e77ab9-f92e-4fb9-a0f2-e79b8c9922c4", "choice_type": "single"} {"question": "The type of joint present between Epiphysis & Diaphysis is", "exp": "PRIMARY CAILAGINOUS JOINT (SYNCHONDROSIS): THESE BONE ARE UNITED BY A PLATE OF HYALINE CAILAGE SO THE JOINT IS IMMOVABLE AND STRONG Description Ref BD CHAURASIA S Handbook of General Anatomy Fouh edition Pg no 63", "cop": 3, "opa": "Fibrous joint", "opb": "Synol joint", "opc": "Synchondrosis", "opd": "Syndesmosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a764af9b-31ec-4764-91e0-4e9100624a6f", "choice_type": "single"} {"question": "Most common second malignancy in patients with femoral retinoblastoma is", "exp": "Patients with family retinoblastoma are at greatly increased risk of developing Osteosarcoma and and some other soft tissue sarcoma.. Alteration in RB pathway, involving INK proteins, cyclin D dependent kinases, and RB family proteins which are present in normal cells lead on to tumor suppressor gene. And associated somatic tissue mutation cause increased risk of other tumors. Refer robbins 9/e 299", "cop": 3, "opa": "Teratoma", "opb": "Medullary carcinomas", "opc": "Osteosarcoma", "opd": "Malignant melanoma", "subject_name": "Anatomy", "topic_name": "miscellaneous", "id": "002ce5ee-3cba-485c-bf86-2edcc70afc0f", "choice_type": "single"} {"question": "Accessory renal aeries are A/E", "exp": "D i.e. Very rare occurancePresence of accessory (supernumerary) renal aeries is the most common renal vascular anomalyQ. It is two times more common than supernumerary renal veins.", "cop": 4, "opa": "End aeries", "opb": "Vascular anomaly", "opc": "2-4 in number", "opd": "Very rare occurance", "subject_name": "Anatomy", "topic_name": null, "id": "fb861a75-811c-4b02-8939-33b9d61857c2", "choice_type": "single"} {"question": "Tibial and common peroneal nerve supplies the muscle (FMGE Dec 2018)", "exp": "Biceps femoris - hybrid muscle - have two nerves supply - Present in posterior compament (lateral) of thigh It has two heads Long head: 1. Originates from inferomedial pa of upper area of ischial tuberosity. 2. Innervated by sciatic nerve - common fibular division. Sho head: 1. Arise from lateral lip of Linea aspera on shaft of femur. 2. innervated by sciatic nerve - common fibular division. It flexes & laterally rotates leg at knee joint; Extends & laterally rotates thigh at hip joint Long head is a pa of hamstrings while sho head is not - gracilis, adductor longus, adductor magnus - belong to medial compament of thigh Muscle Origin Inseion Innervation Function * Gracilis A line on external surface of body of pubis, the inferior pubic ramus & ramus of ischium Medial surface of proximal shaft of tibia. Obturator nerve (L2, L3) Adducts thigh at hip joint & flexes leg at knee joint. * Adductor longus External surface of body of pubis (triangular depression inferior to pubic crest & lateral to pubic symphysis) Linea aspera on middle 1/3rd of shaft of femur Obturator nerve (anterior division L2, L3, L4) Adducts & medially rotates thigh at hip joint * Adductor magnus Ischiopubic ramus Ischial tuberosity Adductor pa - Posterior surface of proximal femur, Linea aspera, medial supracondylar line Hamstring pa - Adductor tubercle, medial supracondylar line Obturator N (L2, L3, L4) Sciatic N (tibial division) (L2, L3, L4) Adducts & medially rotates thigh at hip joint Extends thigh at hip joint.", "cop": 2, "opa": "Gracilis", "opb": "Biceps femoris", "opc": "Adductor longus", "opd": "Adductor magnus", "subject_name": "Anatomy", "topic_name": "FMGE 2018", "id": "a2342190-0573-46b2-9a9a-1035d1070e8b", "choice_type": "single"} {"question": "35 year old female diagnosed to have hyper thyroid disorder. Her thyroid follicle lined by", "exp": "Normal thyroid follicle - simple cuboidal Hyper thyroid follicle - simple columnar Hypo thyroid follicle - simple cuboidal", "cop": 1, "opa": "Simple columnar", "opb": "Simple squamous", "opc": "Simple cuboidal", "opd": "Ciliated columnar", "subject_name": "Anatomy", "topic_name": "Epithelial tissue", "id": "ce4ede3c-e2ef-4eb3-9d30-f4e14e239d29", "choice_type": "single"} {"question": "In case of parathyroid adenoma T/t is", "exp": "Ref: Harrison's 19th edition Pgno :2473-2475 Parathyroid adenoma causes primary Hyperparathyroidism A single parathyroid adenoma (85%) Resection Two adenomas(5%) Resection Hyperplasia of all four glands (10-15%) Resection of 3 1/2 glands Resection of all four glands with auto transplantation of a parathyroid gland in the forearm (brachioradialis) or SCM muscle", "cop": 2, "opa": "Calcitonin and steroid", "opb": "Removal of adenoma", "opc": "Total parathyroidectomy and implantation in arm", "opd": "Total parathyroidectomy", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "55a8ce9d-91ae-4ccf-b04e-32745efb3265", "choice_type": "single"} {"question": "Posterior belly of digastric is attached to", "exp": null, "cop": 3, "opa": "Styloid", "opb": "Hyoid", "opc": "Mastoid notch", "opd": "Thyroid", "subject_name": "Anatomy", "topic_name": null, "id": "b828a70c-dd36-4e4c-b294-51c32c209dc8", "choice_type": "single"} {"question": "Safe and effective method of sterilization of surgical eye instruments is", "exp": "Autoclaving is the safest methods of sterilization Ref khurana 6/e", "cop": 3, "opa": "Acetone", "opb": "Formalin", "opc": "Autoclaving", "opd": "Boiling", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "53835c87-44a6-4637-a491-cee6e4ffeb84", "choice_type": "single"} {"question": "Severity of mitral stenosis is assessed by", "exp": "Ref Harrison 19 th ed pg 1540 In general, the duration of this murmur correlates with the severity of the stenosis in patients with preserved CO. In patients with sinus rhythm, the murmur often reappears or becomes louder during atrial systole (presystolic accentuation).", "cop": 2, "opa": "Loud opening snap", "opb": "Length of murmur", "opc": "Loud S1", "opd": "Splitting S2", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5aa1151b-c421-4fe1-8ac0-3a5ee4f254b0", "choice_type": "single"} {"question": "Epithelium in vocal card is", "exp": null, "cop": 2, "opa": "Pseudo stratified columnar", "opb": "Stratified squamous", "opc": "Simple columnar", "opd": "Cuboidal epithelium", "subject_name": "Anatomy", "topic_name": null, "id": "aabfe503-9a60-442b-880f-f89ecf496633", "choice_type": "single"} {"question": "Lacrimal gland is a derivative of", "exp": "(A) EctodermDERIVATIVES OF EMBRYONIC TISSUESNeuroectodermCranial Neural Crest CellsSurface EctodermMesoderm* Neurosensory retina* Retinal pigment epithelium* Pigmented ciliary epithelium* Nonpigmented ciliary epithelium* Pigmented iris epithelium* Sphincter & dilator muscles of iris* Optic nerve, axons & glia* Vitreous* Corneal Stroma & endothelium* Sclera* Trabecular meshwork* Sheaths & tendons of extraocular muscles* Connective tissues of iris* Ciliary muscles* Choroidal stroma* Melanocytes (uveal & epithelial)* Meningeal sheaths of the optic nerve* Schwann cells of ciliary nerves* Ciliary ganglion* Most orbital bones, cartilage & connective tissue of the orbit* Muscular layer & connective tissue sheaths of all ocular & orbital vessels* Epithelium, glands, cilia of skin of lids & caruncle* Conjunctival epithelium* Lens* Lacrimal gland & drainage system* Vitreous* Fibers of extraocular: muscles endothelial lining of all orbital & ocular blood vessels; temporal portion of sclera, vitreous", "cop": 1, "opa": "Ectoderm", "opb": "Mesoderm", "opc": "Endoderm", "opd": "Neural crest cells", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "e84619c8-b2d1-4e93-a244-51bef5d0ab80", "choice_type": "single"} {"question": "Therapeutic drug monitoring is required for", "exp": "Ref-KDT 6/e p434,435 Indications for therapeutic drug monitoring include: There is an experimentally determined relationship between plasma drug concentration and the pharmacological effect. Knowledge of the drug level influences management. There is a narrow therapeutic window. There are potential patient compliance problems. The drug dose cannot be optimised by clinical observation alone. Examples of drugs analysed by therapeutic drug monitoring: Aminoglycoside antibiotics (gentamicin) Antiepileptics (such as carbamazepine, phenytoin and valproic acid) Mood stabilisers, especially lithium citrate Antipsychotics (such as pimozide and clozapine) Biologic monoclonal antibody drugs (such as adalimumab, ceolizumab pegol and infliximab) Therapeutic drug monitoring can also detect poisoning with above drugs, should the suspicion arise.", "cop": 3, "opa": "Prodrugs", "opb": "Levodopa", "opc": "Lithum carbonate", "opd": "MAO inhibitor", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "5c7786bd-6496-484f-9fe0-84de3a1cc599", "choice_type": "single"} {"question": "Brown atrophy is due to", "exp": "Ref, Robbins 8/e p10,532,7/e10,9/ep64", "cop": 2, "opa": "Fatty necrosis", "opb": "Lipofuscin", "opc": "Haemosiderin", "opd": "Ceruloplasmin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "be3299ed-a149-4abd-8fa4-d24e720e9be6", "choice_type": "single"} {"question": "Sho head of the biceps muscle is attached to", "exp": "Sho head of the biceps brachii arises from the lateral pa of the tip of coracoid process and gets attached to the posterior rough pa of radial tuberosity . B D Chaurasia 7th edition Page no : 91", "cop": 3, "opa": "Supraglenoid tubercle", "opb": "Acromion process", "opc": "Coracoid process", "opd": "Bicipital groove", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a3b57db0-bd0e-49bb-8f9e-b39174351928", "choice_type": "single"} {"question": "Hypercalcemia is seen in", "exp": "Paraneoplastic syndromes of HCC Hypercholesterolemia Hypoglycemia Erythrocytosis Hypercalcemia Ref:Sabiston 20th edition Pgno :1458-1463", "cop": 2, "opa": "Pancreatic cancer", "opb": "HCC", "opc": "CA stomach", "opd": "CA GB", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0826ab76-5737-4034-9c4e-802f6aa50c56", "choice_type": "single"} {"question": "Sarcoidosis doesn't involve", "exp": "Ref Robbins 9/e p693 Sarcoidosis almost always involves the lungs, but it can also affect the skin, eyes, nose, muscles, hea,liver, spleen, bowel, kidney, testes, nerves, lymph nodes, joints, and brain. Granulomas in the lungs can cause narrowing of the airways and inflammation and scarring (fibrosis) of lung tissue Only 5-15p% cases have involvement of sarcoidosis in brain called as neurosarcoidosis, it's very rare", "cop": 1, "opa": "Brain", "opb": "Hea", "opc": "Lung", "opd": "Kidney", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "29ea0a11-5bb1-42d5-a5fd-80208d1625fe", "choice_type": "single"} {"question": "Cardiac septum develops by", "exp": "Cardiac septum developed by 5-8 weeks . Ref - sciencedirect.com", "cop": 1, "opa": "5-8 weeks", "opb": "9-12 weeks", "opc": "12-16 weeks", "opd": "16-18 weeks", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "0222fb4d-4334-41ba-a522-39245af7bb80", "choice_type": "single"} {"question": "Genomic imprinting is seen in", "exp": "Ref Robbins 9/e p172 Angelman syndrome, as might be expected, also can result from uniparental disomy of parental chromosome 15. The Angelman syndrome gene (imprinted on the paternal chro- mosome) is now known to encode a ligase that has a role in the ubiquitin-proteasome proteolytic pathway (Chapter 1). This gene, called, somewhat laboriously, UBE3A, is expressed primarily from the maternal allele in specific regions of the normal brain. In Angelman syndrome, UBE3A is not expressed in these areas of the brain--hence the neurologic manifestations. Prader-Willi syndrome, unlike Angelman syndrome, probably is caused by the loss of function of several genes located on chromosome 15 between q11 and q13. These genes are still being fully characterized.", "cop": 3, "opa": "Klinefelter syndrome", "opb": "Down's syndrome", "opc": "Angelman syndrome", "opd": "Hydatidi form mole", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "05616bfd-586a-40a6-a9e7-0267e9f0a270", "choice_type": "single"} {"question": "Inferior oblique muscle of eye is supplied by", "exp": "Ref BDC volume 3,6th edition pg 208NERVE SUPPLY:The superior oblique is supplied by trochlear nerveThe lateral rectus is supplied by abducent nerveThe superior rectus, medial rectus, inferior rectus and inferior oblique is supplied by occulomotor nerve", "cop": 1, "opa": "Oculomotor nerve", "opb": "Abducent nerve", "opc": "Trochlear nerve", "opd": "Facial nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "e46ab140-479f-4e41-ba6c-592ce28215b2", "choice_type": "single"} {"question": "drugs used for anorexia nervosa", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "cyprohepatidine", "opb": "haloperidol", "opc": "chlorpromazine", "opd": "pimozide", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "10221ca8-4ed0-44bf-9147-1fcc8853bd26", "choice_type": "single"} {"question": "Nerve supply of Pinna is A/E", "exp": "The upper two-thirds of lateral surface is supplied by the auriculotemporal nerve and the lower one-third by the great auricular nerve . The upper two-thirds of medial surface is supplied by the lesser occipital nerve Notes: The auricular muscles are supplied through branches of facial nerve The root is supplied by auricular branch of vagus nerve Ref.BDC volume 3,sixth edition pg 273", "cop": 4, "opa": "Great auricular nerve", "opb": "Auriculotemporal nerve", "opc": "Lesser occipital nerver", "opd": "Greater superficial petrosal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "21172eb0-7344-48f3-84e0-9a7978e0d984", "choice_type": "single"} {"question": "Middle cardiac vein is accompanied by", "exp": "The middle cardiac vein commences at the apex of the hea; ascends in the posterior longitudinal sulcus along with posterior interventricular aery, and ends in the coronary sinus.Ref: V.S Volume 1; 2nd edition; Page: 276", "cop": 3, "opa": "Anterior interventricular aery", "opb": "Left circumflex aery", "opc": "Posterior Interventricular aery", "opd": "Diagonal aery", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "39c06e7a-1af3-4da9-869b-b99678fa4a43", "choice_type": "single"} {"question": "Superior colliculus is concerned with", "exp": "The Superior colliculus is a flattened mass formed of seven concentric alternating laminae of white matter and grey matter.The efferent fibres form Superior colliculus forms tectospinal and tectobulbar tracts, which are probably responsible for the reflex movements of eyes, head, and neck in response to visual stimuli.Unilateral lesion of Superior colliculus results in relative neglect of visual stimuli and inability to track moving objects in the contralateral field of vision, although the eye movements are normal.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 85)", "cop": 3, "opa": "Olfaction", "opb": "Hearing", "opc": "Vision", "opd": "Pain sensation", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "34246e80-8766-4e17-948e-0317fecf5ef4", "choice_type": "single"} {"question": "Most commonly fractured carpal bone", "exp": "• The scaphoid is a BOAT SHAPED carpal bone and has a tubercle in its lateral side.\n• Scaphoid bone is the most commonly fractured carpal bone.\n• Lunate (crescent shaped) is the 2nd most commonly fractured carpal bone.\n• Scaphoid fracture is usually caused by a fall on an outstretched hand with the weight landing on the palm.\n• Scaphoid bone forms the floor of the anatomical snuff box.\n• It articulates with the following bones: radius, lunate, capitate, trapezium, and trapezoid.", "cop": 3, "opa": "Hamate", "opb": "Lunate", "opc": "Scaphoid", "opd": "Capitates", "subject_name": "Anatomy", "topic_name": null, "id": "484b738c-4b82-4119-989b-5b67c40988f1", "choice_type": "single"} {"question": "The efferent limb of the cremaster reflex is provided by", "exp": "-        Cremastric reflex- \n\nAfferent- Femoral branch of genitofemoral nerve\nEfferent- Genital branch of genitofemoral nerve", "cop": 2, "opa": "Femoral branch of the genitofemoral", "opb": "Genital branch of the genitofemoral nerve", "opc": "Ilioinguinal nerve", "opd": "Pudendal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "266e44c6-8247-4f03-aac7-5883b32af997", "choice_type": "single"} {"question": "Superficial perineal space contains", "exp": "Contents: MuscleIschiocavernosus muscleBulbospongiosus muscleSuperficial transverse perineal muscleOtherCrura of penis (males) / crura of clitoris (females)Bulb of penis (males) / vestibular bulb (females)Greater vestibular gland (female)", "cop": 2, "opa": "Sphincter urethrae muscle", "opb": "Ischiocavernosus muscle", "opc": "Deep transverse perinei muscle", "opd": "Bulbourethral gland", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "1d44f9b7-5130-4eee-802e-3a201352d1ab", "choice_type": "single"} {"question": "A child presents with hypochromic microcytic anemia, with normal levels of free erythrocyte protoporphyrin . The most likely diagnosis is", "exp": "Ref Harrison 19 th ed pg 637-638 The diagnosis of b-thalassemia major is readily made during child- hood on the basis of severe anemia accompanied by the characteris- tic signs of massive ineffective erythropoiesis: hepatosplenomegaly, profound microcytosis, a characteristic blood smear ), and elevated levels of HbF, HbA2 , or both.", "cop": 3, "opa": "Iron deficiency anemia", "opb": "Lead toxicity", "opc": "Thalassemia", "opd": "Anemia of chronic disease", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "8b53e4bd-f4fa-4100-8c4e-9c8734e9e857", "choice_type": "single"} {"question": "Area of mitral orifice in adults is", "exp": "The normal area of aoic valve is tz, 3 - 4 cm2 and mitral valve is 4 - 6 cm2Q", "cop": 3, "opa": "6-8 cm2", "opb": "0.5-2 cm2", "opc": "4-6 cm2", "opd": "1-4 cm2", "subject_name": "Anatomy", "topic_name": null, "id": "55175e32-ad95-41e9-9d54-7f7ba3016cea", "choice_type": "single"} {"question": "Function of cholesterol in plasmalemma is to", "exp": "The fluidity of the lipid bilayer is decreased in following three ways Lowering temperature Increasing saturation of fatty acyl tails in phospholipid membrane Increase membrane cholesterol content. Cholesterol interacts with the phospholipid membrane containing fatty acyl chains, compacting them, constraining the motion in bilayers, hence decreasing the fluidity. Ref: Lehninger 30e pg 395.", "cop": 2, "opa": "Increase the fluidity of lipid bilayer", "opb": "Decrease the fluidity of lipid bilayer", "opc": "Facilitate the diffusion of ions into the lipid bilayer", "opd": "Assist in the transpo of hormones across the lipid bilayer", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f932be3f-8112-4e82-b763-e9403f88f30d", "choice_type": "single"} {"question": "Marked deformity is due to", "exp": "Given action - wrist drop Due to radial nerve injury PIN palsy causes - finger drop not wrist drop", "cop": 1, "opa": "Radial nerve", "opb": "Posterior interosseous nerve", "opc": "Ulnar nerve", "opd": "Median nerve", "subject_name": "Anatomy", "topic_name": "Nerve Lesions", "id": "bdc25c83-6844-484d-b4be-155a94617cfe", "choice_type": "single"} {"question": "Epithelium of comea is", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:391 Corneal epithelium: the outermost layer is of non keratinized stratified squamous epithelium. the cells in the deepest layer of the epithelium is columnar.in the middle layers they are polygonal and in the superficial layers they are flattened", "cop": 4, "opa": "Pseudostratified", "opb": "Transitional", "opc": "Statified squamous keratinized", "opd": "Statified squamous non keratinized", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8a386922-53fb-4f34-9e0b-0b6cae283c65", "choice_type": "single"} {"question": "A 59 yr old man with severe myxomatous mitral regurgitation is asymptomatic,wi wia left ventricular ejection fraction of 45% and an endsystollic diameter index of 2.9cm/m2 . The most appropriate treatment is", "exp": "Ref Harrison 19 th ed pg 1545 Valve repair for ischemic MR is associated with lower periopera- tive moality rates but higher rates of recurrent MR over time. In patients with ischemic MR and significantly impaired LV systolic function (EF <30%), the risk of surgery is higher, recovery of LV per- formance is incomplete, and long-term survival is reduced.", "cop": 1, "opa": "Mitral valve repair or replacement", "opb": "No treatment", "opc": "ACE inhibitor therapy", "opd": "Digoxin and diuretic therapy", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2a60aa57-2594-4fc1-85e3-10302e60b0f3", "choice_type": "single"} {"question": "Radiation dose in mammography", "exp": "Mammography Soft tissue radiographs are taken by placing the breast in direct contact with ultrasensitive film and exposing it to low-voltage, high-amperage x-rays. The dose of radiation is approximately 0.1 cGy and, therefore, mammography is a very safe investigation. The sensitivity of this investigation increases with age as the breast becomes less dense. In total, 5% of breast cancers are missed by population-based mammographic screening programmes; even in retrospect, such carcinomas are not apparent. Thus, a normal mammogram does not exclude the presence of carcinoma. Digital mammography is being introduced, which allows manipulation of the images and computer-aided diagnosis. Tomo-mammography is also being assessed as a more sensitive diagnostic modality. Ref:Bailey and love 27th edition Pgno :861", "cop": 3, "opa": "0.1 Gray/study", "opb": "0.01cGray/study", "opc": "0.1 cGray/study", "opd": "0.01 Gray/study", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "b846a213-1838-4447-bd37-66f1d024bee7", "choice_type": "single"} {"question": "Sensory nerve supply of the middle ear cavity is provided by", "exp": "Glossopharyngeal nerve -> Tympanic nerve/Tympanic plexus -> Middle ear\n                                                                                                                Auditory tube\n                                                                                                                Mastoid antrum", "cop": 2, "opa": "Facial", "opb": "Glossopharyngeal", "opc": "Trigeminal", "opd": "Vagus", "subject_name": "Anatomy", "topic_name": null, "id": "ad9d6b4f-4613-4e8f-8779-59a70a8aaca4", "choice_type": "single"} {"question": "Nerve likely to be injured in posterior dislocation of the Hip joint is", "exp": "Dislocation of the hip may be posterior (more common), anterior (less common), or central (rare). The sciatic nerve may be injured in posterior dislocations.Ref: BDC 6th edition (Abdomen and lower limb) pg: 154", "cop": 3, "opa": "Superior gluteal nerve", "opb": "Inferior gluteal nerve", "opc": "Sciatic", "opd": "Pudendal", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "775baff9-096f-4d03-b283-87414aa47206", "choice_type": "single"} {"question": "Site of transplantation in Islet cell transplant for Diabetes mellitus is", "exp": "The islets are then purified from the dispersed tissue by density-gradient centrifugation and can be delivered into the recepient liver (the preferred site for transplantation) by injection into the poal vein Ref: Bailey and love 27th edition Pgno :1552", "cop": 2, "opa": "Skin", "opb": "Injected into the poal vein", "opc": "Liver", "opd": "Pelvis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "91ec5518-373b-4a7e-9246-d7a72ba7640c", "choice_type": "single"} {"question": "The tensile strength of the wound stas and increases after", "exp": "Wounds do not begin to gain tensile strength from collagen until 5 - 7 days. Wound achieves around 20 % by 3 weeks, and around 60 % by four months. Scar tissue continues to remodel for at least 6 - 12 months after an injury.", "cop": 2, "opa": "Immediately after suturing", "opb": "3-4 days", "opc": "7-10 days", "opd": "1 month", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "44dd5d46-5799-4119-bb66-2179604c29f0", "choice_type": "single"} {"question": "Bregma is the name given to the junction of the", "exp": "Bregma:\n\nBregma is the meeting point between coronal and sagittal sutures.\nSeen in norma verticalis view of skull.\nIn foetal skull, this is the site of a membranous gap, called anterior fontanelle. It ossifies at 18 months of age.", "cop": 1, "opa": "Coronal and sagittal sutures", "opb": "Frontal bone with the nasal bone", "opc": "Lambdoid and sagittal sutures", "opd": "Parietal & Occipital bone", "subject_name": "Anatomy", "topic_name": null, "id": "30c0cabf-6865-4aca-9a52-05a53307ef3a", "choice_type": "single"} {"question": "Main feature of chemotaxis is", "exp": "Ref Robbins 8/e p45 ..9/e p77 Chemotaxis. After extravasating from the blood, leuko- cytes move toward sites of infection or injury along a chem- ical gradient by a process called chemotaxis. Both exogenous and endogenous substances can be chemotactic for leuko- cytes, including the following: * Bacterial products, paicularly peptides with N-formyl- methionine termini * Cytokines, especially those of the chemokine family * Components of the complement system, paicularly C5 * Products of the lipoxygenase pathway of arachidonic acid (AA) metabolism, paicularly leukotriene B4 (LTB4) These mediators, which are described in more detail later, are produced in response to infections and tissue damage and during immunologic reactions. Leukocyte infiltration in all of these situations results from the actions of various combinations of mediators. Chemotactic molecules bind to specific cell surface receptors, which triggers the assembly of cytoskeletal con- tractile elements necessary for movement. Leukocytes move by extending pseudopods that anchor to the ECM and then pull the cell in the direction of the extension. The direction of such movement is specified by a higher density of chemokine receptors at the leading edge of the cell. Thus, leukocytes move to and are retained at the site where they are needed. The type of emigrating leukocyte varies with the age of the inflammatory response and with the type of stimulus. In most forms of acute inflammation, neutrophils predomi- nate in the inflammatory infiltrate during the first 6 to 24 hours and are replaced by monocytes in 24 to 48 hours (Fig. 2-6). Several factors account for this early abundance of neutro- phils: These cells are the most numerous leukocytes in the blood, they respond more rapidly to chemokines, and they may attach more firmly to the adhesion molecules that are rapidly induced on endothelial cells, such as P- and E-selectins. In addition, after entering tissues, neutrophils are sho-lived--they die by apoptosis and disappear within 24 to 48 hours--while monocytes survive longer. There are exceptions to this pattern of cellular infiltration,", "cop": 4, "opa": "Increase random movement of neutrophil", "opb": "Increase adhesive Ness to intima", "opc": "Increased phagocytosis", "opd": "Unidirectional locomotion of neutrophil", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5312769b-7e7d-4153-a5a6-2523792c7d94", "choice_type": "single"} {"question": "Extentsion of neck occurs at", "exp": "C1 and C2 form a unique set of aiculations that provide a great degree of mobility for the skull. C1 serves as a ring or washer that the skull rests upon and aiculates in a pivot joint with the dens or odontoid process of C2. Approximately 50% of flexion extension of the neck happens between the occiput and C1; 50% of the rotation of the neck happens between C1 and C2. Ref - medscape.com", "cop": 1, "opa": "Atlanto-occipital joint", "opb": "C4-C5 veebra", "opc": "Atlantoaxial joint", "opd": "C6-C7", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "59f70ca0-e649-4947-be4d-c14835c40102", "choice_type": "single"} {"question": "Bochdalek hernia occurs in", "exp": "BOCHDALEK HERNIA: Usually left sided It is congenital diaphragmatic hernia Deficiency in left pleuroperitoneal cavity Left lung hypoplasia Right lung is also compressed Cyanosis at bih NEONATAL EMERGENCY MORGAGNI HERNIA Mostly on right side Antero-medial & Retrosternal Transverse colon herniates in front of hea Less common than Bochdalek hernia", "cop": 2, "opa": "Antero-lateral pa of diaphragm", "opb": "Postero-lateral pa of diaphragm", "opc": "Retro-sternal area", "opd": "posterior to diaphragm", "subject_name": "Anatomy", "topic_name": "Umblicial cord and diaphragm", "id": "1d7fdde7-b1fb-4aeb-b694-492c19cf793d", "choice_type": "single"} {"question": "Loss of lacrimation occurs due to injury of", "exp": "Parasympathetic secretomotor nerve fibres destined for the lacrimal gland arise from the lacrimal nucleus of the facial nerve. They travel via the great petrosal nerve to reach the lacrimal gland. Consequently injuries of the greater petrosal nerve can cause loss of lacrimation.", "cop": 2, "opa": "Nasocilliary nerve", "opb": "Greater petrosal nerve", "opc": "Anterior ethmoidal nerve", "opd": "Supraorbital nerve", "subject_name": "Anatomy", "topic_name": null, "id": "9e4d4a05-204f-43b7-a4be-392854f9a4ca", "choice_type": "single"} {"question": "M2 choline receptor is located at", "exp": "M2 receptors are located at Hea, Nerves, Smooth musclesM1NervesM2Hea, Nerves, Smooth musclesM3Glands, smooth muscle, endotheliumM4CNSM5CNSNMSkeletal muscle, Neuromuscular junctionNNCNS, postganglionic cell body, dendritesKatzung 13e pg:105", "cop": 1, "opa": "Hea", "opb": "Lungs", "opc": "Skeletal muscle", "opd": "Glands", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a5eb85f2-ada2-4442-8ecc-2d3b02991cfa", "choice_type": "single"} {"question": "Aortic hiatus contains", "exp": "Aortic hiatus contain azygous vein and thoracic duct", "cop": 3, "opa": "Left gastric vein and thoracic duct", "opb": "Thoracic duct and hemiazygos vein", "opc": "Azygos vein and thoracic duct", "opd": "Left vagus and thoracic duct", "subject_name": "Anatomy", "topic_name": null, "id": "8e7a13fa-fe0f-4f34-8f8b-92baf790580b", "choice_type": "single"} {"question": "Ligament of Berry is formed by", "exp": "The posterior layer of the thyroid capsule is thick. On either side it forms a suspensory ligament for the thyroid gland known as ligament of Berry .The ligaments are attached chiefly to the cricoid cartilage, and may extend to the thyroid cartilage. They support the thyroid gland, and do not let it sink into the mediastinum.", "cop": 2, "opa": "Investing layer of Deep Cervical fascia", "opb": "Pretracheal layer", "opc": "Prevertebral layer", "opd": "Pharyngobasilar fascia", "subject_name": "Anatomy", "topic_name": null, "id": "9d221759-4316-4fec-8d5e-240c96c6af0a", "choice_type": "single"} {"question": "Most dependent Bronchopulmonary segment in Erect position is", "exp": "Most dependent Bronchopulmonary segment in Erect position is Right posterior basal segment.", "cop": 3, "opa": "Left Superior segment", "opb": "Right Superior segment", "opc": "Right posterior basal segment", "opd": "Left posterior basal segment", "subject_name": "Anatomy", "topic_name": null, "id": "b3c89e7f-f8cc-424f-95f7-0a1fa1228eef", "choice_type": "single"} {"question": "Half life of factor 8", "exp": "Factor VIII is also called as anti hemophilic factor Its half life is 8-12 hrs Ref: Harrison's 19th edition Pgno :138", "cop": 2, "opa": "4 hrs", "opb": "8 hrs", "opc": "24 hrs", "opd": "30 hrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "92ecdf25-6ae8-495b-877b-3da11122ed8e", "choice_type": "single"} {"question": "Marked dermatome is", "exp": "Dermatome supply of the marked area is S2", "cop": 4, "opa": "L4", "opb": "L5", "opc": "S1", "opd": "S2", "subject_name": "Anatomy", "topic_name": "Nerve supply of Lower Limb", "id": "2f00464b-b29b-4ac2-9246-1b70377abb1a", "choice_type": "single"} {"question": "An agent that activates natural killer cells and is useful in renal cell carcinoma is", "exp": "Ref-Katzung 10/e p816 Recombinant IL-2 is used for the treatment of maligant melanoma and renal cell carcinoma", "cop": 1, "opa": "Aldesleukin", "opb": "Etanercept", "opc": "Leflunomide", "opd": "Thalidomide", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "5d77a71b-f3d4-4a53-a097-62ea260115e2", "choice_type": "single"} {"question": "Tensor tympani is supplied by", "exp": "The tensor tympani lies in a bony canal that opens at its lateral end on the anterior wall of the middle ear, and its medial end on the base of skull. Nerve supply: MANDIBULAR NERVE The fibres pass through the nerve to the medial pterygoid, and through the otic ganglion, without any relay. Development: From the mesoderm of first branchial arch Action: Tensing the tympanic membrane Ref:BDC 6th edition pg 281 (vol 3)", "cop": 2, "opa": "Maxillary branch of 5th nerve", "opb": "Mandibular branch of 5th nerve", "opc": "Facial nerve", "opd": "Lingual nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "051fad12-3426-458c-a634-38ecfd7e7193", "choice_type": "single"} {"question": "Medial boundary of anatomical snuffbox is formed by", "exp": "ANATOMICAL SNUFF BOX:-Elongated triangular depression seen on the lateral side of the dorsum of hand when the thumb is hyperflexed. BOUNDARIES:1. Anterolaterally-tendon of abductor pollicis longus,tendon of extensor pollicis brevis.2. Posteromedially-tendon of extensor pollicis longus.3. Floor-scaphoid and trapezium.4. Roof-skin and superficial fascia.Contents:-1. Radial aery.Structures crossing the roof deep to skin:-1. Cephalic vein.2. Terminal branch of superficial radial nerve. Pulsations of radial aery felt here.Tenderness felt here indicates fracture of scaphoid bone.Cephaloc vein at this site can be used for giving iv fluids. {Reference: Vishram Singh , page no.171} Figure 9.33,page no:122 BD chaurasia", "cop": 1, "opa": "Extensor pollicis longus", "opb": "Extensorpollicis brevis", "opc": "Abductor pollicis longus", "opd": "Flexor carpi ulnaris", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "8910b07a-1055-4561-8a79-4cf9f20d7eb6", "choice_type": "single"} {"question": "Suntentaculum tali is present on", "exp": "Sustentaculum tali is a bony projection present on Calcaneus, on medial surface.", "cop": 3, "opa": "Talus", "opb": "Navicular", "opc": "Calcaneus", "opd": "Cuneiform", "subject_name": "Anatomy", "topic_name": null, "id": "b7f551c0-01b8-4eb5-b380-5511895733e2", "choice_type": "single"} {"question": "The following is not a feature of malignant transformation by culturedc", "exp": "Ref biology of the cell p357-364 Both normal cells and cancer cells can be cultured in-vitro , however they behave quite differently normal cell: show replicative senescence .is cells pass through limited number of cell division before they decline in vigor and die it may caused by inability to synthesise telomerase", "cop": 2, "opa": "Increased cell density", "opb": "Increased requirement for growth factors", "opc": "Alterations of cytoskeleton structure", "opd": "Loss of anchorage", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "56a3e242-b2f4-45e3-a6d6-3e9257f84387", "choice_type": "single"} {"question": "Liver abscess ruptures most commonly in", "exp": ".", "cop": 2, "opa": "Pleural cavity", "opb": "Peritoneal cavity", "opc": "Pericardial cavity", "opd": "Bronchus", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "e06b836d-135b-4462-a36a-7c169f831f7a", "choice_type": "single"} {"question": "Foot eversion is caused by", "exp": "Foot eversion occurs at subtalar joint by Peroneus longus, Peroneus brevis and Peronius Teius. Inversion of foot done by Tibialis anterior and Tibialis posterior.", "cop": 2, "opa": "Extensor digitorum", "opb": "Peroneus longus", "opc": "Tibialis anterior", "opd": "Tibialis posterior", "subject_name": "Anatomy", "topic_name": "Muscles of Lower Limb", "id": "c7287f22-1329-4bf8-b6b2-ab2196d27d4c", "choice_type": "single"} {"question": "Ceruminous glands present in the ear are", "exp": "Th e ceruminous glands secrete the wax of the ear. Th ey are modifi ed sweat glands lined by a columnar, cuboidal or squamous epithelium. REF : Inderbir Singh's Textbook of Human Histology,Seventh edition, pg.no.,412.", "cop": 2, "opa": "Modified eccrine glands", "opb": "Midified apocrine glands", "opc": "Mucous gland", "opd": "Modified holocrine glands", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "955ba9c5-e62c-4d52-98b5-c2e8cbd0fbcf", "choice_type": "single"} {"question": "Origin of sho head of Biceps", "exp": "Biceps brachi have two heads sho head and long head The sho head of biceps arise along with coracobrachialis from the tip of the coracoid process, Long head of biceps arise from supraglenoid tubercle of the scapula and from the glenoid labrum Mnemonic Biceps brachii origins: you walk shoer to a street corner.you ride longer on a superhighway. Sho head originates from coracoid process. Long head originates from the supraglenoid tubercle. Reference: BD chaurasia vol 1, 7th edition page no 91 Figure:8.3,page no: 89 BD chaurasia , 6th edition", "cop": 1, "opa": "Coracoid process", "opb": "Acromion process", "opc": "Supra glenoid tubercle", "opd": "Bicipital groove", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "4937df2c-4b3d-497b-9740-8e74b7034ae8", "choice_type": "single"} {"question": "The commonest mode of inheritance of congenital hea disease is", "exp": "Ref Harrison 19 th ed pg 1516 The most common bih defects are cardiovascular in origin. These malformations are due to complex multifactorial genetic and environ- mental causes. Recognized chromosomal aberrations and mutations of single genes account for <10% of all cardiac malformations. Congenital hea disease (CHD) complicates ~1% of all live bihs in the general population--about 40,000 bihs/year--but occurs more frequently in the offspring (about 4-10%, depending on maternal CHD type) of women with CHD. Owing to the remarkable surgical advances over the last 60 years, >90% of afflicted neonates and children now reach adulthood; women with CHD may now frequently successfully bear children after competent repairs.", "cop": 4, "opa": "Autosomal dominant", "opb": "Autosomal recessive", "opc": "Sexlinked dominant", "opd": "Multifactorial", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9547e171-36ac-4f3b-b646-ac02f2b2a473", "choice_type": "single"} {"question": "The following structure does not pass through flexor retinaculum", "exp": "FLEXOR RETINACULUM Carpel tunnel.Transverse carpal ligament. Strong fibrous band which bridges anterior concavity of carpus and conves it into osseofibrous tunnel called carpal tunnel for the passage of flexor tendons of the digits. Rectangular.Formed due to thickening of deep fascia in front of carpal bones. Attachments: medial-pisiform, hook of hamate.Lateral-tubercle of scaphoid and crest of trapezium. Structures passing superficial to flexor retinaculum:-(medial to lateral)1. Ulnar nerve 2. Ulnar aery 3. Posterior cutaneous branch of ulnar nerve.4. Tendon of palmaris longus.5. Palmar cutaneous branch of median nerve.6. Superficial palmar branch of radial aery. Structures passing deep to flexor retinaculum:-1. Tendon of FDS2. Tendon of FDP 3. Tendon of FPL.4. median nerve. Ulnar bursa-tendons of FDS&FDP.Radial bursa- tendon of flexor pollicis Flexor carpi radialis pass through separate canal. CARPAL TUNNEL SYNDROME:-Injury to median nerve in carpal tunnel.Causes:-Tenosynovitis of flexor tendons.MyxedemaRetention of fluid in pregnancy Fracture dislocation of lunate bone.Osteoahritis of wrist. Symptoms:-1. Feeling of burning pain or \" pins & needles \" along lateral 3 and half digits especially at night.2. Weakness of thenar muscles.3. No sensory loss over thenar eminence.4. Ape thumb deformity if left untreated.5. Positive phalens abd tinel's sign.Phalen' sign-flexion of both wrists against each other for one minute reproduces the symptoms.Tinel's sign- percussion over flexor retinaculum reproduces symptoms. MNEMONIC structures passing deep to flexor retinaculum:\" SPM fuLLy Boring Flexor digitorum Superficialis tendon, flexor digitorum Profundus tendon, Median nerve, flexor poLLicis longus , Bursae - radial and ulnar. {Reference: vishram singh, page no.196,} Figure:9.15,page no:113,BD chaurasia , 6th edition,upper limb & thorax.", "cop": 1, "opa": "Ulnar N", "opb": "Median N", "opc": "Flexor digitorum profundus", "opd": "Flexor digitorum superficialis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "6c9ebdc7-8d66-4b68-982a-761223c5de66", "choice_type": "single"} {"question": "Most frequently damaged cranial nerve with a motor component", "exp": "Traumatic Cranial Neuropathies: the most common cranial nerves which recieve traumatic injuries include olfac, tory, facial and audiovestibular nerves the lower cranial nerves are less often involved", "cop": 3, "opa": "Occulomotor", "opb": "Trigeminal", "opc": "Facial", "opd": "Glossopharyngeal", "subject_name": "Anatomy", "topic_name": null, "id": "93b61204-2613-4f45-9fbd-57e3419ce084", "choice_type": "single"} {"question": "Tumor marker of HCC", "exp": "Tumor markers of HCC Protein induced by Vitamin K absence (PIVKA; Des-gamma-carboxy prothrombin); glypican-3; AFP fractions Lectin fraction-3 of SFP (AFP-L3) is highly specific to HCC and also indicator of poorly differentiated histology and unourable prognosis Serum AFP level is elevated above 20ng/mp in >70% of patients with HCC Monoclonal antibody HeoPar-1(hepatocyte paraffin-1) identifies a unique antigen on hepatocyte mitochondria and is used to identify hepatocytes or HCC Ref:Sabiston 20th edition 1458-1463", "cop": 1, "opa": "AFP", "opb": "Alpha fucosidases", "opc": "DCGP", "opd": "Carbohydrate antigen", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "8397baaf-752f-418f-b09c-1947ecc76217", "choice_type": "single"} {"question": "The aery most commonly responsible for bleeding in massive hemoptysis is", "exp": ".", "cop": 1, "opa": "Bronchial", "opb": "Pulmonary", "opc": "Intercostal", "opd": "Intersegmental", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "512e9824-55a9-42b6-989a-17fc92a4ccfc", "choice_type": "single"} {"question": "Wire loop lesions are seen in", "exp": "Ref Harrison 17/e p2077; Robbins 8/e p218;9/e p224 Subendothelial deposits create a homogenous thickness iof the capillary wall called wire loop lesson.which can be seen on light microscopy", "cop": 1, "opa": "SLE", "opb": "Diabetic nephropathy", "opc": "Benign nephrosclerosis", "opd": "Wegener's granulomatosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b3937bc0-299c-42aa-a1f0-5c2226e0e905", "choice_type": "single"} {"question": "Voluntameer ram will receive a new drugin Phase 1 clinical trial. The clearance and volume of distribution of the drug in Ram are 1.386L/hr and 80L respectively. They have life of the drug in him would be approximately", "exp": "Ref-Katzung 10/e p38,39 t1/2=0.0693xVd/CL", "cop": 3, "opa": "83hr", "opb": "77hr", "opc": "40hr", "opd": "0.02hr", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "6f20fca1-2b60-4e9d-a035-9ec7c8bce762", "choice_type": "single"} {"question": "The most suitable test to assess iron stores is", "exp": "Reg Harrison 19 th ed pg 627,628 The serum ferritin level is a better indicator of iron overload than the marrow iron stain. However, in addition to storage iron, the marrow iron stain provides information about the effective delivery of iron to develop- ing erythroblasts.", "cop": 2, "opa": "Serum iron", "opb": "Serum ferritin", "opc": "TIBC", "opd": "Transferrin saturation", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "2904a4e4-7a6d-4238-b1be-9adbd660ef20", "choice_type": "single"} {"question": "Convergent muscle among the following is", "exp": "Convergent muscle is one where all the fibres converge at the insertion (Fan shaped)\nEg - Temporalis", "cop": 3, "opa": "Subscapularis", "opb": "Deltoid", "opc": "Temporalis", "opd": "Pectoralis minor", "subject_name": "Anatomy", "topic_name": null, "id": "710177ef-c2f6-428b-a34f-cd5551e23e0f", "choice_type": "single"} {"question": "A patient sustains a knife wound through the right fouh intercostals space, 2 cm to the right of the sternum. The area most likely penetrated by the knife is the", "exp": "The right border of the hea is approximately 1 to 2 cm to the right of the right border of the sternum; therefore, the knife probably did not hit the hea. The middle lobe of the right lung extends from the level of the fouh costochondral junction to the level of the fifth intercostal space. The middle lobe is most likely at the level of the fouh intercostal space.", "cop": 2, "opa": "Right upper lobe of the lung", "opb": "Right middle lobe of the lung", "opc": "Right lower lobe of the lung", "opd": "Right atrium of the hea", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "6ed275d2-a711-461f-beb1-aca540311498", "choice_type": "single"} {"question": "The structure that lies lateral to distal radial tubercle", "exp": "The structure that lies lateral to distal radial tubercle are: Tendons of Extensor carpi radialis brevis and longus. Distal radial tubercle (Lister's tubercle) is located at the distal dorsal aspect of the radius It is a bony prominence that can be easily palpated. Function: It acts as a pulley for the Extensor Pollicis Longus tendon, changing it's mechanical direction of action.", "cop": 2, "opa": "Extensor pollicis longus", "opb": "Extensor carpi radialis longus", "opc": "Brachioradialis", "opd": "Extensor carpi ulnaris", "subject_name": "Anatomy", "topic_name": "Muscles of arm and forearm region & Cubital fossa", "id": "c02c97aa-cb2d-403d-909c-efcc2d5851f8", "choice_type": "single"} {"question": "Muscle causing supination of forearm", "exp": "SUPINATION & PRONATION OF FOREARM:-Perform skilled movements.Elbow is semiflexed in mid prone position.Palm turned down in pronation and upwards in supination.Rotatory movement of forearm which occur at superior and inferior radioulnar joints around a veical axis.In supination, radius and ulna lie parallel to each other.In pronation, rotation of lower end of radius on the head of ulna.Supination more powerful than pronation., because it has antigravity movement, it is performed by powerful muscles.Muscles involved:-Supination:-1. Supinator.2. Biceps brachii- supinates when elbow is flexed.3. Brachioradialis-supinates pronated forearm to midprone position.Pronation:-1. Pronator teres.2. Pronator quadratus.3. Brachioradialis- pronates the supinated forearm to midprone position .{Reference:vishram singh, pg no.145}", "cop": 1, "opa": "Biceps brachii", "opb": "Brachioradialis", "opc": "Flexor digitorum superficialis", "opd": "Anconeus", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "3eb365b8-0afd-446b-a9bd-e6f3800bf9f6", "choice_type": "single"} {"question": "Difference between typical cervical & thoracic vertebra", "exp": "In cervical vertebrae, the transverse process is pierced by foramen transversaria", "cop": 2, "opa": "Has a triangular body", "opb": "Has a foramen transversarium", "opc": "Superior articular facet directed backwards & upwards", "opd": "Has a large vertebral body", "subject_name": "Anatomy", "topic_name": null, "id": "161470d3-f053-43c6-8bd0-8140f6295b5a", "choice_type": "single"} {"question": "Skin and fascia of great toe drains into", "exp": "Superficial inguinal lymph nodes are located in the superficial fascia of the inguinal region. They are divided into two groups horizontal and veical resembling the letter T.The horizontal group lie below and parallel to the inguinal ligament. The veical group lies along the terminal pa of the great saphenous vein. The horizontal group is divided into medial and lateral groups.Lateral group receives lymph from the gluteal region, lateral half of anterior abdominal wall below the umbilicus and the entire lower limb except lateral pa of foot, heel and lateral pa of leg.Deep inguinal lymph nodes receive lymph from superficial inguinal lymph nodes. The external iliac nodes drain lymph from the inguinal nodes and they are fuher drained into common iliac nodes. The internal iliac nodes drain lymph from the pelvic viscera.Reference: clinical anatomy for students a problem solving approach, Neeta v Kulkarni, 2nd edition, page no.840,841,719", "cop": 1, "opa": "Superficial inguinal lymph nodes", "opb": "External iliac nodes", "opc": "Internal iliac nodes", "opd": "Deep inguinal nodes", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "d7b9d552-4e8a-4091-a5b7-5b38a8110433", "choice_type": "single"} {"question": "Coronal suture is placed between", "exp": "1. Coronal suture: This is placed between the frontal bone and the two parietal bones. The suture crosses the cranial vault from side to side and runs downwards and forwards2. Sagittal suture: It is placed in the median plane between the two parietal bones. 3. Lambdoid suture: It lies posteriorly between the occipital and the two parietal bones, and it runs downwards and forwards across the cranial vault.4. Metopic suture: This is occasionally present in about 3 to 8% individuals. It lies in the median plane and separates the two halves of the frontal bone.Ref: Chaurasia; Volume 3; 6th edition; Chapter 1; Page no: 4", "cop": 3, "opa": "Two parietal bones", "opb": "Two halves of frontal bone", "opc": "Frontal bone and two parietal bones", "opd": "Occipital and two parietal bones", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9e1ff85c-3130-4f12-8d20-7d1737bc10af", "choice_type": "single"} {"question": "Incomplete closure of ectodermal cleft is know to cause", "exp": "Inderbir Singh&;s Human embryology Tenth edition Pg 364 Failure of the choroidal fissure to obliterate completely may lead to deficiencies( coloboma)of various layers of eyeball including iris ciliary body and choroid", "cop": 4, "opa": "Retinal detachment", "opb": "Iridodonesis", "opc": "Retinoblastoma", "opd": "Coloboma of iris and retina", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7e22c309-249f-431e-895c-fb6de31326cc", "choice_type": "single"} {"question": "Most common intracranial malignancy is", "exp": "Glioblastoma multiforme (GBM) is the most common and deadliest of malignant primary brain tumors in adults and is one of a group of tumors referred to as gliomas. Classified as a Grade IV (most serious) astrocytoma, GBM develops from the lineage of star-shaped glial cells, called astrocytes, that suppo nerve cells. GBM develops primarily in the cerebral hemispheres but can develop in other pas of the brain, brainstem, or spinal cord. Refer Robbins page no 1308", "cop": 1, "opa": "Glioblastoma multiforme", "opb": "Ependymoma", "opc": "Choroid angioma", "opd": "Pinealoma", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "6b105bbb-08cd-4713-80d5-aaa2294a1b6d", "choice_type": "single"} {"question": "Tarsal bone interposed between the proximal and distal rows is", "exp": "The navicular bone is boat-shaped. It is interposed between the talus and the three cuneiform (Latin wedge) bones. In other words, it is interposed between the proximal and distal rows.Ref: Chaurasia; Volume 2; 6th edition; Page no: 33", "cop": 4, "opa": "Talus", "opb": "Calcaneus", "opc": "Cuboid", "opd": "Navicular", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "e591215a-c976-4688-be23-a6baa669295a", "choice_type": "single"} {"question": "Vasa bre is the name of", "exp": "Splenic aery (branch of celiac trunk) supply greater curvature of stomach by it following branches: Sho gastric aeries which are called as vasa bre. (carried by Splenogastric ligament) Long gastric aery called left gastroepiploic aery. Jejunal vasa recta (long aeries) & ileal vasa recta (sho) are straight aeries coming from arcades in mesentery of jejunum & ileum.", "cop": 2, "opa": "Long gastric aeries", "opb": "Sho gastric aeries", "opc": "Iliea vasa recta", "opd": "Jejunal vasa recta", "subject_name": "Anatomy", "topic_name": "Stomach and aerial supply of abdomen", "id": "63e3bf51-c251-4a30-b730-f27cddbbdf04", "choice_type": "single"} {"question": "Parietal peritoneum is lined by", "exp": "SIMPLE SQUAMOUS EPITHELIUM - The cells of this epithelium are flattened. In sections they appear so thin that bulgings are produced on the surface by nuclei. In surface view the cells have polygonal outlines that interlock with those of adjoining cells. A simple squamous epithelium lines the alveoli of the lungs, the free surfaces of peritoneum, pleura and pericardium. Here it is given the name mesothelium. It also lines the inside of blood vessels,where it is called endothelium, and Of the hea where it is called endocardium. REF : Inderbir Singh's Textbook of Human Histology, seventh edition, pg.no., 2.", "cop": 1, "opa": "Simple squamous", "opb": "Stratified squamous", "opc": "Cuboidal", "opd": "Columnar", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0e810f2f-25af-4136-bc89-d677cc06a314", "choice_type": "single"} {"question": "A 60 yr old lady is concerned about the wrinkles around her eyes.This is due to defect in", "exp": "Collagen cross-linking: Cross linking occurs when a protein linked to other protein,lipid or sugar which is necessary for normal collagen function. Abnormal cross linking causes wrinkles/ages skin which is due to glucose mediated advance glycation end products(AGE),UV mediated free radical damage. Collagenase: Defect in collagen leads to increased level of collagen Collagenase inhibitor are given to treat wrinkles Desmosine: Desmosine is formed by 3allsyl side chains and one unaltered lysyl side chain of elastin. Fibrillin: It is a glycoprotein secreted by fibroblasts. It forms a framework of elastin deposition Defect in fibrillin-1 results in Marfans syndrome Reference: Harpers illustrated biochemistry 30th edition", "cop": 4, "opa": "Collagenase", "opb": "Desmosine", "opc": "Fibrillin", "opd": "collagen cross linking", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "998aec65-b729-4819-bcc1-dba0dc0e1b0e", "choice_type": "single"} {"question": "Most common location of accessory spleen", "exp": "Accessory spleen, in other words supernumerary spleens, splenunculi, or splenules, results from the failure of fusion of the primordial splenic buds in the dorsal mesogastrium during the fifth week of fetal life. Incidence of accessory spleen in the population is 10%-30% of patients in autopsy series and 16% of patients undergoing contrast enhanced abdominal CT. Although the most common location for an accessory spleen is splenic hilum (75%) and pancreatic tail (25%) , it can occur anywhere in the abdomen including gastrosplenic or splenorenal ligaments, wall of stomach or bowel , greater omentum or the mesentery, and even in the pelvis and scrotum. Accessory spleen usually measures 1 cm in diameter, but its size varies from a few milimeters to centimeters. Also the number of accessory spleens can vary from one to six . Accessory spleens are usually incidentally detected and asymptomatic, but in case of unexpected locations, accessory spleen can be of clinical impoance. Ref - radiologyassistant.com", "cop": 1, "opa": "Hilum of spleen", "opb": "Greater omentum", "opc": "Lesser omentum", "opd": "Duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "620f465e-eb5b-4bdd-98b2-228c42b36d39", "choice_type": "single"} {"question": "Heriditory spherocytosis is caused by", "exp": "Spectrin causes membrane loss leading to spherical shape of rbc", "cop": 1, "opa": "Spectrin deficiency", "opb": "Hb deficiency", "opc": "Incresed sodium levels", "opd": "Increased calcium levels", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "d99e06db-1769-493c-b42d-cd7316cf59f6", "choice_type": "single"} {"question": "Hunterian perforators are seen in", "exp": "Hunterian perforator is seen in middle one third of thigh.It is a perforating vein that connects the great saphenous vein with the femoral vein .The great saphenous vein is a superficial vein while the femoral vein is a deep vein.It is present in the hunter&;s canal. Other perforating veins include, 3 medial ankle perforators of Cockett and Boyd&;s perforator at upper end of calf. reference: clinical anatomy for students, problem solving approach,neeta v kulkarni, 2nd edition ,page no.837", "cop": 4, "opa": "Upper thigh", "opb": "Lower thigh", "opc": "Calf", "opd": "Mid thigh", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "4cb40d29-bcf1-4291-b642-d5ee822ea7ce", "choice_type": "single"} {"question": "Enzymes that protects the brain from free radical injury is", "exp": "Ref Robbins 7/e p17; Harrison 17/e p2572;9/e p48 Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or paitioning) of thesuperoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2).", "cop": 2, "opa": "Myeloperoxidase", "opb": "Superoxide dismutase", "opc": "MAO", "opd": "Hydroxylase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "0ea969fa-652e-4257-96e6-6211a9b05778", "choice_type": "single"} {"question": "Quickening will be felt in pregnancy at", "exp": "Quickening Pregnant woman will feel slight fluttering movement in her abdomen by fifth month of pregnancy. This is known as quickening, which gradually increase in intensity. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 330", "cop": 2, "opa": "Second month", "opb": "Fifth month", "opc": "10 weeks", "opd": "12 weeks", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "8a69ace0-f019-4c61-b4c9-342f43a8a863", "choice_type": "single"} {"question": "Subclan steal syndrome results due to obstruction of", "exp": "The proximal pa of left subclan is blocked on left side so no flow in veebral and to left arm. Blood from right veebral enters left veebral and flows back to supply left arm.", "cop": 1, "opa": "1st pa of subclan aery", "opb": "2nd pa of subclan aery", "opc": "3rd pa of subclan aery", "opd": "Subclan vein", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "35f1c95a-3c0b-4991-b5dc-93ebb8cf7f31", "choice_type": "single"} {"question": "Cartilage of second arch is", "exp": null, "cop": 2, "opa": "Meckels cartilage", "opb": "Reicherts cartilage", "opc": "Pharyngeal cartilage", "opd": "Thyroid cartilage", "subject_name": "Anatomy", "topic_name": null, "id": "c21d0d54-1ce7-4faa-9449-d3f56aa697b9", "choice_type": "single"} {"question": "Development of labia majora is from", "exp": "Labia Majora and Scrotum develops from the same structure known as Labio scrotal swelling. Genital ridge forms testes,ovary Urethral folds also known as genital folds forms the labia minora. Urogenital sinus forms urinary bladder, urethra And lower pa of vagina.", "cop": 4, "opa": "Urogenital sinus", "opb": "Urethral fold", "opc": "Genital ridge", "opd": "Genital swelling", "subject_name": "Anatomy", "topic_name": "Development of GU system and Neuro-vascular supply of pelvis & perineum", "id": "c25699fa-0b5a-4900-aa93-20d10e99f12d", "choice_type": "single"} {"question": "During active labor cervical dilatation per hour in primi is", "exp": "Active labor: Cervix dilatation to atleast >6 cm Regular uterine contractions are present Rate of dilatation is atleast 1.2 cm/hr for nulliparous and 1.5cm/ hr for parous women", "cop": 1, "opa": "1.2 cm", "opb": "1.5 cm", "opc": "1.7 cm", "opd": "2 cm", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "d45bde3a-6313-441e-b0d1-ca29f7301def", "choice_type": "single"} {"question": "Power grip of hand is a function of", "exp": "Power grip is by extrinsic muscles of hand which originate in the forearm and inse in the hand - Long flexors Precision grip is a function of the intrinsic muscles of hand which originate and inse in the hand. Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 860.", "cop": 1, "opa": "Long flexors", "opb": "Sho flexors", "opc": "Palmaris brevis", "opd": "Lumbricals", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "d619e3bf-cab1-45ec-bc6c-8773dbc93936", "choice_type": "single"} {"question": "Structure related to deltopectoral groove is", "exp": "the deltopectoral groove - The cephalic vein, the deltoid branch of the thoraco-acromial aery, and one or two deltopectoral lymph nodes lie in the deltopectoral groove, under the deep fascia on the medial side of the septum. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no., 43", "cop": 2, "opa": "Axillary aey", "opb": "Cephalic vein", "opc": "Basilic vein", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "65bed609-35c5-4892-baef-51b0d7fa2a3e", "choice_type": "single"} {"question": "Muscle used in normal walk during stance and swing", "exp": "Each leg goes through stance phase and swing phase in normal walking.\nStance phase - Foot on ground. 60% of gait. \nMain muscles involved are\n\n   Heel strike - quadriceps, hamstrings, tibialis anterior\n   Mid stance - quadriceps, hamstrings, tibialis anterior, gluteus maximus\n   Push off - gastrocnemius -soleus\n\nSwing phase - Foot not on ground, 40% of gait.\nMain muscles involved are\n\n   Acceleration - quadriceps\n   Swing through - iliopsoas\n   Deceleration - hamstrings and tibialis anterior.", "cop": 2, "opa": "Ilio psoas", "opb": "Tibialis Anterior", "opc": "Popliteus", "opd": "Gastrocnemius-soleus", "subject_name": "Anatomy", "topic_name": null, "id": "34968e01-fdb9-4061-bdeb-28960a34581b", "choice_type": "single"} {"question": "The last tributary of the azygos vein is", "exp": "Right bronchial vein near the terminal end of azygos vein. BD CHAURASIA'S HUMAN ANATOMY VOLUME 1. 6TH Edition. page no-224", "cop": 3, "opa": "Right superior intercostal vein", "opb": "Hemi-azygos vein", "opc": "Right bronchial vein", "opd": "Accessory azygos vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "f4466154-9ed4-45f4-81b0-092b3485e3d0", "choice_type": "single"} {"question": "Interosseous membrane of forearm is piereced by", "exp": "-The anterior interosseous nerve and vessels lie in close relation to the anterior surface of the interosseous membrane of forearm stretching between the interosseous borders of radius and ulna.At the upper margin of the pronator quaadratus, the anterior interosseous vessels pass through the interosseous membrane to enter the posterior compament of forearm. -The lower pa of the posterior surface of interosseous membrane is closely related to the anterior interosseous aery and posterior interosseous nerve.The posterior interosseous vessels enter the posterio compament through the gap between oblique cord and upper margin of the interosseous membrane. -reference; clinical anatomy for students ,problem solving appproach,neeat v kulkarni, page no.79", "cop": 2, "opa": "Brachial aery", "opb": "Anterior interosseous aery", "opc": "Posterior interosseous aery", "opd": "Ulnar recurrent aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "a623eab1-06a3-4a98-81bc-2069db6b588b", "choice_type": "single"} {"question": "A 20 year old male presents with extrapyramidal symptoms and liver damage. Diagnosis", "exp": "Wilson's disease It is characterized by excessive deposition of copper in the liver, brain and other tissues Clinical features Liver disease during first decade of life or with neuropsychiatric illness during 3rd decade Kayser-Fleischer ring - due to deposition of copper in Descemet's membrane in the limbs of corners Ref: Sabiston 20th edition", "cop": 1, "opa": "Wilson's disease", "opb": "Huntington's disease", "opc": "Parkinsons's disease", "opd": "Hemochromatosis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "0b02c7c1-9590-4466-bfea-75a3e8a07f81", "choice_type": "single"} {"question": "Antihelminthic drugs that is effective against blood fluke ,liver fluke, lung fluke and cysticercus is", "exp": "Ref-KDT 6/e p814,815 Drug of choice for treatment of flukes (except Praziquantal liver fluke) and cestodes : Triclabendazole Drug of choice for treatment of liver fluke:DEC Drug of choice for treatment of filariasis : Ivermectin Drug of choice for treatment of onchocercal and strongyloides For rest all helminthes :Albendazole", "cop": 3, "opa": "Albendazole", "opb": "Praziquantal", "opc": "Ivermectin", "opd": "Thiabendazole", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "4c9c64b8-1687-4349-9866-512b7c9bf757", "choice_type": "single"} {"question": "SLE like reaction is caused by", "exp": "SLE like syndrome is caused due to S-SULPHONAMIDES H-HYDRALAZINE I-ISONIAZIDE P-PROCAINAMIDE Ref-KDT 7/e p66", "cop": 1, "opa": "Hydralazine", "opb": "Rifampicin", "opc": "Paracetamol", "opd": "Furosemide", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "727a3efd-7dd0-4355-8073-514f975edb01", "choice_type": "single"} {"question": "The dorsal pa of the ventral mesogastrium forms(2018)", "exp": "The lesser omentum is formed by two layers of peritoneum separated by a variable amount of connective tissue and fat. It is derived from the ventral mesogastrium. Ref:- Gray's anatomy, pg num:- 1101", "cop": 2, "opa": "A) Greater omentum", "opb": "B) Lesser omentum", "opc": "C) Faliciform ligament", "opd": "D) Lineorenal ligament", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "b79b199d-e413-4431-b188-ef9af2ea6ba0", "choice_type": "single"} {"question": "The most common site of Tracheostomy", "exp": "Tracheostomy is an operation in which the trachea is opened and a tube inseed into it to facilitate breathing. It is most commonly done in the retrothyroid region after retracting the isthmus of the thyroid gland. A suprathyroid tracheostomy is liable to stricture, and an infrathyroid one is difficult due to the depth of the trachea and is also dangerous because numerous vessels lie anterior to the trachea here.Ref: BD Chaurasia; Volume 3; 6th edition; Anterior Triangle of the Neck; Page no: 139", "cop": 2, "opa": "Superior thyroid region", "opb": "Retro thyroid region", "opc": "Infra thyroid region", "opd": "Lateral thyroid region", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "d3db33e3-a2d0-41b7-80f6-810cfee3a573", "choice_type": "single"} {"question": "Humans become infected by M.tuberculosis commonly by", "exp": "M.tuberculosis is mainly transmitted by direct inhalation of aerosolised bacilli contained in the droplet nuclei of expectorated sputum. Generated while coughing. sneezing,or speaking of infected patients. There may be as many as 3000 infectious nuclei per cough. The tiny droplets may remain suspended in the air for several hours and are easily inhaled. Ref: Textbook of microbiology; Ananthanarayan and paniker's; 10th edition; Pg: 355", "cop": 3, "opa": "Ingestion", "opb": "Contact", "opc": "Inhalation", "opd": "Inoculation", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "ae4229bf-518e-4107-bd92-9a24ff05f267", "choice_type": "single"} {"question": "Metabolic changes associated with excessive vomiting includes the following", "exp": "Vomiting causes loss of gastric secretions which include HCl & K+ ions, resulting in metabolic alkalosis, hypokalemia and hypochloremia. However note that the moderate to severe hypokalemia seen with excessive vomiting is not merely explained by loss of K+ ions in vomiting. \"In fact the hypokalemia is primarily due to increased renal K+ excretion. Loss of gastric contents results in volume depletion and metabolic alkalosis, both of which promote Kaliuresis.", "cop": 3, "opa": "Metabolic acidosis", "opb": "Hyperchloremia", "opc": "Hypokalemia", "opd": "Decreases bicarbonates", "subject_name": "Anatomy", "topic_name": "General surgery", "id": "15eaf7e0-9e13-4bfa-a263-cf102ecc5fe8", "choice_type": "single"} {"question": "Alcholholic Hyaline Seen in alcoholic liver disease is composed of", "exp": "Refer Robbins page no 843", "cop": 2, "opa": "Lipofuscin", "opb": "Eosinophilic intracytoplasmic inclusions", "opc": "Basophilic intracytoplasmic inclusions", "opd": "Hemazoin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "332fe15e-7739-4bc1-8634-4bce25a40a5c", "choice_type": "single"} {"question": "Most common joint involved in gouty ahitis is", "exp": "Most common joint involved in gout is big toe i.e,metatarsophalangeal joint of great toe Refer Harrison 20th e p 2165 maheswari 9th ed", "cop": 3, "opa": "Knee joint", "opb": "Hip joint", "opc": "MP joint of the big toe", "opd": "MP joint of thumb", "subject_name": "Anatomy", "topic_name": "Joint disorders", "id": "f247b3b2-9de3-4e86-a379-3bb7118e7007", "choice_type": "single"} {"question": "The most common histologic type of thyroid cancer is", "exp": "Papillary carcinoma accounts for 80% of all thyroid malignancies in iodine-sufficient areas and is the predominant thyroid cancer in children and individuals exposed to external radiation.\" The incidence of primary malignant tumours of the thyroid gland Also, remember - Thyroid carcinoma is the most common malignancy of the endocrine system Ref : Schwaz 9/e p1361", "cop": 3, "opa": "Medullary type", "opb": "Follicular type", "opc": "Papillary type", "opd": "Anaplastic type", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "aa55e35b-ebce-46d2-a441-acaecdedbed4", "choice_type": "single"} {"question": "Rate of elimination of a new drug is 20mg/hr it is steady state plasma concentration of 10mg/L, then it's renal clearance will be", "exp": "Ref-Katzung 10/e p35 Clearance=Rate of elimination/plasma concentration 20mg/hr /10mg/L =2L/hr", "cop": 2, "opa": "0.5L/hr", "opb": "2.0L/hr", "opc": "5.0L/hr", "opd": "20L/hr", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "35e6db1e-2198-483e-93ad-c4c0456c7a8e", "choice_type": "single"} {"question": "Blastocyst implantation close to internal os causes", "exp": "A i.e. Placenta pre- When the placenta is implanted paially or completely over the lower uterine segment, over and adjacent to the internal os, it is called placenta pre", "cop": 1, "opa": "Placenta pre", "opb": "Placenta percreta", "opc": "Placenta increta", "opd": "Abruptio Placenta", "subject_name": "Anatomy", "topic_name": null, "id": "60554c01-0f41-4a7a-bb95-a60ce2509565", "choice_type": "single"} {"question": "Investigation of choice for high risk breast cancer in female is", "exp": "MRI Indicated in scarred breast, implants and borderline lesions for breast conservation Investigation of choice for implant related complications. Gold standard for imaging breast in females with implants Ref: Sabiston 20th edition Pgno :826-828", "cop": 1, "opa": "MRI", "opb": "CT- PET", "opc": "Mammography", "opd": "USG", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "8586c5e3-cfec-47fb-ac1d-a3bd8d78b432", "choice_type": "single"} {"question": "The type of joint between the sacrum and the coccyx is a", "exp": "The sacrococcygeal symphysis is an amphiahrodial (slightly mobile) joint, formed between the oval surface at the apex of the sacrum, and the base of the coccyx.The movements which take place between the sacrum and coccyx, and between the different pieces of the latter bone, are forward and backward; they are very limited. Their extent increases during pregnancy.A zygapophyseal joint (or facet joint) is a veebral joint between the superior aicular process of one veebra and the inferior aicular process of the one adjacent. It is of plane synol variety. In fact, all the joints of veebra are plane synol Except the median one- which is a symphysis (as expected *).*All midline joints tend to be symphysis, only very few Exceptions are there. E.g., spheno-occipital joint, which is a synchondrosisInterveebral discs (or interveebral fibrocailage) lie between adjacent veebrae in the spine. Each disc forms a secondary cailaginous (symphysis) joint to allow slight movement of the veebrae, and acts as a ligament to hold the veebrae together.Discs consist of an outer annulus fibrosus, which surrounds the inner nucleus pulposus. The annulus fibrosus consists of several layers of fibrocailage. The strong annular fibers contain the nucleus pulposus and distribute pressure evenly across the disc. The nucleus pulposus contains loose fibers suspended in a mucoprotein gel the consistency of jelly. The nucleus of the disc acts as a shock absorber, absorbing the impact of the body&;s daily activities and keeping the two veebrae separated.The disc can be likened to a doughnut: whereby the annulus fibrosis is similar to the dough and the nucleus pulposis is the jelly. If one presses down on the front of the doughnut the jelly moves posteriorly or to the back. When one develops a prolapsed disc the jelly/ nucleus pulposis is forced out of the doughnut/ disc and may put pressure on the nerve located near the disc. This will give one the symptoms of sciatica if the disc herniation is at lumbosacral region.There is one disc between each pair of veebrae, Except for the first cervical segment, the atlas. There are a total of twenty-three discs in the spine.When the annulus fibrosus tears due to an injury or the aging process, the nucleus pulposus can begin to extrude through the tear, most commonly postero-lateral. This is called disc herniation. Near the posterior side of each disc, all along the spine, major spinal nerves extend out to different organs, tissues, extremities etc. It is very common for the herniated disc to press against these nerves (pinched nerve) causing radiating pain, numbness, tingling, and diminished strength and/or range of motion. In addition, the contact of the inner nuclear gel, which contains inflammatory proteins, with a nerve can also cause significant pain and muscle spasm. Nerve-related pain is called radicular pain.", "cop": 1, "opa": "Symphysis", "opb": "Synostosis", "opc": "Synchondrosis", "opd": "Syndesmosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "c555dd62-8c6a-4790-b5b4-a7269e86333f", "choice_type": "single"} {"question": "Inverse supinator jerk is", "exp": "A i.e. C5, C6", "cop": 1, "opa": "C5, C6", "opb": "C6, C7", "opc": "L5, Si", "opd": "La, Si", "subject_name": "Anatomy", "topic_name": null, "id": "d26c95c5-52fc-475e-a8d6-423f4d482d87", "choice_type": "single"} {"question": "reversible lens granular deposits is caused by", "exp": "chlorpromazine is a typical anti psychotic that has lot of mentioned side effects namely Blue grey discolouration of skin reverse lens granular deposits obstructive jaundice retrograde ejaculation REf. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 925", "cop": 1, "opa": "chlorpromazine", "opb": "risperidone", "opc": "paliperidone", "opd": "olanzapine", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "41a02aae-d340-4782-b043-7782c1a4e6a6", "choice_type": "single"} {"question": "Number of muscles in middle ear", "exp": "The two muscles of middle ear are tensor tympani and stapedius. Both act simultaneously to damp down the intensity of high pitched sound waves and thus protect the internal ear. Notes: The tensor tympani is supplied by the mandibular nerve The stapedius is supplied by the facial nerve Ref BDC volume3,sixth edition pg 280", "cop": 2, "opa": "1", "opb": "2", "opc": "3", "opd": "4", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "fee5de57-0ec3-404f-bbec-909622b92315", "choice_type": "single"} {"question": "Derivative of ultimobranchial body", "exp": "PHARYNGEAL POUCH DEVELOPS INTO 1st Tympanic cavity and eustachian tube 2nd Tonsillar epithelium 3rd Ventrally: thymus Dorsally: inferior parathyroid 4th Superior parathyroid 5th Ultimobranchial body The ultimobranchial body will be found attached to pharyngeal pouch 4. It receives some neural crest cells which will form the parafollicular C cell of thyroid gland; which help in the production of hormone calcitonin.", "cop": 3, "opa": "Thyroid", "opb": "Capsule of thyroid", "opc": "Parafollicular 'C' cells", "opd": "2nd branchial pouch", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "bf543996-caf0-405f-b1d9-202168a9e229", "choice_type": "single"} {"question": "Hyoglossus muscle inserts into", "exp": "Key Concept: \nHyoglossus muscle inserts into lateral part of tongue.", "cop": 3, "opa": "Tip of the tongue", "opb": "Base of the tongue", "opc": "Lateral part of the tongue", "opd": "Hyoid bone", "subject_name": "Anatomy", "topic_name": null, "id": "80b07c1a-cdb8-44c3-a05c-4382da127d8d", "choice_type": "single"} {"question": "Extension at MCP joint is by", "exp": "(A) Extensor Digitorum # Extensor digitorum muscle actions include Extension of interphalangeal, metacarpophalangeal and wrist joints.> All Palmar interossei adduct the digit to which they are attached towards the middle finger + flex the digit at MCP joint & extend IP joints.> All Dorsal interossei abduct the digits away from the line of the middle finger + flex the digit at MCP joint & extend IP joints.> Lumbrical muscles flex the metacarpophalangeal joints, and extend the interphalangeal joints of the digit into which they are inserted.", "cop": 1, "opa": "Extensor Digitorum", "opb": "Dorsal Interossei", "opc": "Palmar Interossei", "opd": "Lumbricals", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "d6e4c93d-bade-4352-a409-a921309b7e80", "choice_type": "single"} {"question": "Antischkow cells are characteristic of the", "exp": "Refer robbins 9/e p558 Anitschkow (or Anichkov) cells are often cells associated with rheumatic hea disease. Anitschkow cells are enlarged macrophages found within granulomas (called Aschoff bodies) associated with the disease. The cells are also called caterpillar cells, as they have an ovoid nucleus and chromatin that is condensed toward the center of the nucleus in a wavy rod-like pattern that to some resembles a caterpillar. Larger Anitschkow cells may coalesce to form multinucleated Aschoff giant cells.Anitschkow cells were named after the Russian pathologist Nikolay Anichkov. Squamous epithelial cells with nuclear changes resembling Anitschkow cells have also been observed in recurrent aphthous stomatitis, iron deficiency anemia, children receiving chemotherapy, as well as in healthy individuals", "cop": 1, "opa": "Acute rheumatic fever", "opb": "Yellow fever", "opc": "Malarial spleen", "opd": "Itp", "subject_name": "Anatomy", "topic_name": "Cardiovascular system", "id": "4df40960-3e5f-42f9-8b69-b4de744c199b", "choice_type": "single"} {"question": "Example for Denticulate suture", "exp": "Types of sutures:Plane: Internasal sutureSerrate: Coronal sutureDenticulate: Lambdoid sutureSquamous: Parieto-Temporal sutureReference: Chourasia; 6th Edition; 4th page", "cop": 3, "opa": "Internasal suture", "opb": "Coronal suture", "opc": "Lambdoid suture", "opd": "Parietotemporal suture", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4456e5b2-9887-434f-8f27-e0f5e9a330de", "choice_type": "single"} {"question": "Chronic urethral obstruction due to benign prismatic hyperplasia can lead to the following change in kidney parenchyma", "exp": "Chronic urethral obstruction because of urinary calculi, prostatic hyperophy, tumors, normal pregnancy, tumors, uterine prolapse or functional disorders cause hydronephrosis which by definition is used to describe dilatation of renal pelvis and calculus associated with progressive atrophy of the kidney due to obstruction to the outflow of urine Refer Robbins 7yh/9,1012,9/e. P950", "cop": 3, "opa": "Hyperplasia", "opb": "Hyperophy", "opc": "Atrophy", "opd": "Dyplasia", "subject_name": "Anatomy", "topic_name": "Urinary tract", "id": "e9ad821a-c438-4965-9f77-760819dfa155", "choice_type": "single"} {"question": "Medial rotator of thigh is", "exp": "Ans: D Gluteus minimus.Medial rotation of hip joint:Tensor fasciae latae.Anterior fibres of glutei medius & minimus.", "cop": 4, "opa": "Gluteus maximus", "opb": "Obturator externus", "opc": "Obturator internus", "opd": "Gluteus minimus", "subject_name": "Anatomy", "topic_name": null, "id": "86d60587-06ae-481b-9963-303181bf086b", "choice_type": "single"} {"question": "Most common type of pathological changes seen in Rabies are", "exp": "Refer Robbins page no Pg 1277 Histopathologic evidence of rabies encephalomyelitis (inflammation) in brain tissue and meninges includes the following: Mononuclear infiltration Perivascular cuffing of lymphocytes or polymorphonuclear cells Lymphocytic foci Babes nodules consisting of glial cells Negri bodies", "cop": 4, "opa": "Meningitis", "opb": "Cranial aeritis", "opc": "Ventriculitis", "opd": "Brain stem encephalitis", "subject_name": "Anatomy", "topic_name": "Nervous system", "id": "9932e7c3-9910-492b-b5e1-ff0c1d8e9e6d", "choice_type": "single"} {"question": "Secretomotor fibres to Lacrimal gland relay in", "exp": null, "cop": 2, "opa": "Otic ganglion", "opb": "Pterygopalatine ganglion", "opc": "Geniculate ganglion", "opd": "trigeminal ganglion", "subject_name": "Anatomy", "topic_name": null, "id": "8af1c498-ac6e-4a8c-bc39-509c234ad33e", "choice_type": "single"} {"question": "Philtrum of upper tip is derived from", "exp": null, "cop": 3, "opa": "Maxillary prominence", "opb": "Mandibular prominence", "opc": "Medial nasal process", "opd": "Lateral nasal process", "subject_name": "Anatomy", "topic_name": null, "id": "d88f2e02-7b99-4ad5-9f2e-0233ac753c5a", "choice_type": "single"} {"question": "Treatment of Acute lymphangitis requires", "exp": "Ref : bailey and love 25e p945", "cop": 1, "opa": "Antibiotics and rest", "opb": "Immediate multiple incisions", "opc": "Immediate lymphangiography", "opd": "No special treatment", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cd03cebe-0491-48c3-9fb1-e3b9312d8fe8", "choice_type": "single"} {"question": "Dislocation of the veebra is uncommon in thoracic region because in this region", "exp": "The superior aicular process is directed backward, upward and laterally (BUL) in the thoracic region. It interlocks with the corresponding inferior aicular facet making a strong aiculation rendering dislocation in the thoracic region uncommon.", "cop": 1, "opa": "The aicular processes are interlocked", "opb": "The veebral body is long", "opc": "Anterior longitudinal ligament is strong", "opd": "Spinous process is long and pointed", "subject_name": "Anatomy", "topic_name": "Back region", "id": "589ddd42-9339-4397-a47d-cc3dcf3f49a9", "choice_type": "single"} {"question": "The following structure does not pass through flexor retinaculurn", "exp": "Ulnar nerve Flexor retinaculum (F.R.)Is a thickening of deep fascia which bridges the ant. concavity of the carpus and conves it into an osteofascial tunnel, the carpal tunnel.Structures passing beneath the flexor retinaculum from medial to lateral are:Flexor digitorum superficialis tendon & post. to these flexor digitorum profundus tendonsMedian N.Flexor pollicis longusFlexor carpi radialis", "cop": 1, "opa": "Ulnar N.", "opb": "Median N.", "opc": "Flexor digitorum profundus", "opd": "Flexor digitorum superficialis", "subject_name": "Anatomy", "topic_name": null, "id": "8da4d377-d0c5-446c-ae7a-20c5ce1d2c4e", "choice_type": "single"} {"question": "A clot size of a clenched fist indicates blood loss of approximately", "exp": "Measurement of Blood Loss Clot size of a clenched fist is 500 ml. Blood loss in a closed tibial fracture is 500-1500 ml; in a fracture femur is 500-2000 ml. Weighing the swab before and after use is an impoant method of on-table assessment of blood loss. Ref: SRB's Manual of Surgery 6th edition Pgno :120", "cop": 4, "opa": "100 ml", "opb": "200 ml", "opc": "300ml", "opd": "500 ml", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2e391e90-8d01-4267-84c0-9fc9c47b7011", "choice_type": "single"} {"question": "Over growth of skin structure at a localised region is", "exp": "Ref Robbins 8/e p262; 9/e p13 An overgrowth of a skin structure at a localised region is likely to be indigenous as well as benign , this is more likely to be a hamaoma .it is now considered as a neoplasm", "cop": 1, "opa": "Hamaoma", "opb": "Malignant tumor", "opc": "Choristoma", "opd": "Polyp", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "535a6c3c-ba5d-4dfb-9c22-85933cf3d1d1", "choice_type": "single"} {"question": "One of the following opens in the middle meatus of the nose", "exp": "The middle meatus lies underneath the middle concha.it presents the following features: 1.the ethmoidal bulla is a rounded elevation produced by the underlying middle ethmoidal sinuses which open at upper margin of bulla. 2. Hiatus semilunar 3. Infundibulum 4. The opening of maxillary air sinus is located in posterior pa of the hiatus semilunaris.it is often represented by two openings. 5. The opening of the anterior ethmoidal air sinus is present behind the opening of frontal air sinus 6. The opening of frontal air sinus is seen in the anterior pa of hiatus semilunar Ref.BDC volume 3.Sixth edition pg 243", "cop": 4, "opa": "Naso-lacrimal duct", "opb": "Eustachian tube", "opc": "Sphenoidal air sinus", "opd": "Maxillary air sinus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "815616af-2335-4c34-abbc-33fe58693b67", "choice_type": "single"} {"question": "Inferior most structure of right hilium is", "exp": "Superior pulmonary vein is the anterior most and inferior pulmonary vein is the inferior most structures of both lung hiliumQ.Upper most structure of hilum (root) of lung is pulmonary aery (left side)Q and epaerial (superior lobar) bronchus (on right side) Q.", "cop": 2, "opa": "Bronchus", "opb": "Inferior pulmonary vein", "opc": "Pulmonary aery", "opd": "Inferior bronchial vein", "subject_name": "Anatomy", "topic_name": null, "id": "495465a2-3170-4e69-9cde-88c38972a4a6", "choice_type": "single"} {"question": "Transitional epithelium is seen in", "exp": "INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:320", "cop": 3, "opa": "Esophagus", "opb": "Vagina", "opc": "Urinary bladder", "opd": "Trachea", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f182f677-7242-4a22-8c2d-2657c73824e8", "choice_type": "single"} {"question": "Abdominal Aorta Bifurcates at the level of", "exp": "Abdominal Aorta Bifurcates at the Lower border of L4", "cop": 3, "opa": "Body of L3", "opb": "Lower border of L3", "opc": "Lower border of L4", "opd": "Body of L4", "subject_name": "Anatomy", "topic_name": null, "id": "892a0708-fa8a-437f-b080-e8484a558aae", "choice_type": "single"} {"question": "Nerve supply of muscles of soft palate is/are", "exp": "Ref BDC volume 3,6th edition pg 223MOTOR NERVE SUPPLY:All muscles of soft palate except tensor veli palatini are supplied by pharyngeal plexus. The fibers of this plexus are derived from the cranial pa of the accessory nerve through vagus. The tensor veli palatini is supplied by mandibular nerve.GENERAL SENSORY NERVES:The middle and posterior lesser palatine nerves which are branches of maxillary nerve through the pterygopalatine ganglionThe glossopharyngeal nerveSPECIAL SENSORY OR GUSTATORY NERVESThe nerves carrying taste sensations from the oral surface are contained in the lesser palatine nerves.SECRETOMOTOR NERVESThese are also contained in the lesser palatine nerves.", "cop": 1, "opa": "Glossopharynegal Nerve", "opb": "Vagus Nerve", "opc": "Trigeminal Nerve", "opd": "Greater palantine nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f731f21f-2c1d-47e8-af3e-309cae7715c0", "choice_type": "single"} {"question": "The muscle of hand that contains a sesamoid bone is", "exp": "The tendon of inseion of adductor pollicis on the medial side of base of proximal phalanx of thumb contains a sesamoid bone.Reference: Textbook of anatomy, Upper limb, and thorax, Vishram Singh, 2nd edition, page no.144", "cop": 4, "opa": "Flexor pollicis brevis", "opb": "Flexor pollicis longus", "opc": "Opponens pollicis", "opd": "Adductor pollicis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "8fc055da-d19c-4db3-90ba-93c2cf84d8a3", "choice_type": "single"} {"question": "A child in status epilepticus should not be given", "exp": "Seizures are one of the adverse effects of clonazepam Drugs Commonly Used In Status Epilepticus*Lorazepam *Midazolam*Diazepam*Phosphenytoin*Paraldehyde*Phenobarbital*Pentobarbital *Propofol*Thiopentone*ValproateSteps in management of status epilepticusIV Diazepam 0.1-0.3 mg/kg (or)Lorazepam 0.05-0.1 mg/kg|Fosphenytoin 15-20 PE/kg (PE - Phenytoin Equivalents)|Phenobarbitone 10-20 mg/kg (or)Valproate 20 mg/kg /Levetiracetam|Midazolam 0.05-0.2 mg/kg (or)Propofol 1-3 mg/kg (or)Thiopental IV Infusion|Isoflurane anaesthesia(Refer: Nelson's Textbook of Paediatrics, 19thedition, pg no:2039)", "cop": 1, "opa": "Clonazepam", "opb": "Phos Phenytoin", "opc": "Phenobarbital", "opd": "Diazepam", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0d2eafd9-b395-4680-9ccf-1c83b9129f31", "choice_type": "single"} {"question": "A woman has septic aboion done vegetation on tricuspid Valve is likely to go to", "exp": "Ref Harrison 19 th ed pg 819 Septic pulmonary emboli, which are com- mon with tricuspid endocarditis, cause cough, pleuritic chest pain, nodular pulmonary infiltrates, or occasionally pyopneumothorax. Infection of the aoic or mitral valves presents with the typical clinical features of endocarditis, including peripheral manifestations.", "cop": 1, "opa": "Septic infracts to lung", "opb": "Liver", "opc": "Spleen infracts", "opd": "Emboli to brain", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e742abfa-ae12-4440-b3f9-21738e1e1fb6", "choice_type": "single"} {"question": "Number of vertebrae in human vertebral column is", "exp": "(D) 33# Human vertebral column usually consists of 33 vertebrae:> 24 Presacral vertebrae: 7 cervical, 12 thoracic, and 5 lumbar)> Sacral veretebrae (5 fused sacral vertebrae) and> Coccyx vertebrae (4 frequently fused coccygeal vertebrae).", "cop": 4, "opa": "30", "opb": "31", "opc": "32", "opd": "33", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "c50be7fa-e95f-455c-99ea-bc3b91e28caa", "choice_type": "single"} {"question": "The most common form of fetal traumatic injury incurred during extraction is", "exp": "The most frequent single cause of death in breech presentation is intracranial hemorrhage due to tentorial tears, these tears are the result of sudden excessive pressure on the after coming head and may be aptly described as the snapping of the internal greyropes of the cranium", "cop": 4, "opa": "Rupture of liver", "opb": "Rupture of spleen", "opc": "Intraadrenal hemorrhage", "opd": "Intracranial hemorrhage", "subject_name": "Anatomy", "topic_name": "Abnormal labor", "id": "e7ef5e47-a268-4cbe-98a2-f9bfd7eea019", "choice_type": "single"} {"question": "Marker of cell membrane is/are", "exp": "Na+/K+-ATPase -- plasmalemma, glucose-6-phosphatase---endoplasmic reticulum, galactosyltransferase----- Golgi apparatus, succinate dehydrogenase ----- mitochondria, acid phosphatase --- lysosomes, catalase---- peroxisomes and lactate dehydrogenase --- cytosol.", "cop": 1, "opa": "5-Nucleotidase", "opb": "LDH", "opc": "Galactosyltransferase", "opd": "Catalase", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "71797ff2-370f-4531-a008-46d070f5d757", "choice_type": "single"} {"question": "A patient with abdomen injury presents to the emergency depament with signs of peritonitis and shock. Airway and breathing were secured and IV fluids were staed with two large bore cannulas. The next line of management should be", "exp": ". Haemodynmically unstable-investigations need to be suspended as immediate surgical correction needed. Pg No. 372 bailey 27th edition", "cop": 2, "opa": "FAST", "opb": "Exploratory laparotomy under general anaesthesia", "opc": "Inseion of abdominal drain followed by laparotomy", "opd": "Laproscopy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6893b0eb-7b2a-4bfa-9416-fd6c5db4d4e2", "choice_type": "single"} {"question": "Feature seen in common peroneal nerve injury", "exp": "COMMON PERONEAL NERVE:- Smaller terminal branch of sciatic nerve.Root value: dorsal division of ventral rami of L4,L5,S1,S2.Beginning: begins in back of thigh as a smaller subdivision of the sciatic nerve. Course:lies in upper lateral pa of popliteal fossa. It turns around the lateral surface of the fibula. Then it lies in the substance of peroneus longus muscle.Terminates by dividing into two terminal branches- superficial and deep peroneal. Commonest nerve to be paralysed.Causes of injury:1. Fracture neck of fibula.2. Lathi injury on lateral side of knee joint.3. Due to plaster on leg.- nerve get compressed between hard plaster and neck of fibula. To prevent this cotton must be placed on the upper lateral side of the leg. Effects of injury:-1. Motor loss: dorsiflexors and eveors of foot affected. Results in foot drop. Foot is plantar flexed due to paralysis of muscle of anterior compament.2. Sensory loss: back of leg, lateral side of leg and dorsum of foot.3. Aicular loss: lateral side of knee joint. {Reference: BDC 6E pg no.176}", "cop": 3, "opa": "Inversion inability", "opb": "Loss of sensation of sole", "opc": "Foot drop", "opd": "Loss of extension of great toe", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "8a8f1c36-85bc-4261-985f-f3e34fa5f779", "choice_type": "single"} {"question": "A 25 year old female complaints of discharge of blood from a single duct in her breast. The most appropriate treatment is", "exp": "Discharges from the nipple Discharge can occur from one or more lactiferous ducts. Management depends on the presence of blood in the discharge or discharge from a single duct. Treatment Treatment must firstly be to exclude a carcinoma by occult blood test and cytology. Simple reassurance may then be sufficient but, if the discharge is proving intolerable, an operation to remove the affected duct or ducts can be performed (microdochectomy). MICRODOCHECTOMY It is impoant not to express the blood before the operation as it may then be difficult to identify the duct in theatre. A lacrimal probe or length of stiff nylon suture is inseed into the duct from which the discharge is emerging. A tennis racquet incision can be made to encompass the entire duct or a periareolar incision used and the nipple flap dissected to reach the duct. The duct is then excised. A papilloma is nearly always situated within 4-5cm of the nipple orifice. Ductoscopy (inspection of the internal structure of the duct system) using microendoscopes is technically feasible but generally disappointing. The affected duct may not be visualised and biopsy systems are currently rudimentary. Ref: Bailey and love 27th edition Pg no : 864, 865", "cop": 2, "opa": "Radical excision", "opb": "Microdochectomy", "opc": "Radical mastectomy", "opd": "Biopsy to rule out carcinoma", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "1d416a5c-e37c-4858-a0fb-3ed39355d669", "choice_type": "single"} {"question": "The inheritance pattern of familial retinoblastoma is", "exp": "Ref Robbins 7/e p1442,299- 300,9/e p292-293 In hereditary retinoblastoma, mutations in the RB1gene appear to be inherited in an autosomal dominant pattern. Autosomal dominant inheritance means that one copy of the altered gene in each cell is sufficient to increase the risk of cancer. A person with hereditary retinoblastoma may inherit an altered copy of the RB1 gene from one parent, or the altered gene may be the result of a new mutation that occurs in an egg or sperm cell or just after feilization. For retinoblastoma to develop, a mutation involving the other copy of the RB1 gene must occur in retinal cells during the person's lifetime. This second mutation usually occurs in childhood, typically leading to the development of retinoblastoma in both eyes. In the non-hereditary form of retinoblastoma, typically only one eye is affected and there is no family history of the disease. Affected individuals are born with two normal copies of the RB1 gene. Then, usually in early childhood, both copies of the RB1 gene in ceain retinal cells acquire mutations. People with non-hereditary retinoblastoma are not at risk of passing these RB1 gene mutations to their children. However, without genetic testing it can be difficult to tell whether a person with retinoblastoma in one eye has the hereditary or the non-hereditary form of the disease.", "cop": 2, "opa": "Autosomal recessive", "opb": "Autosomal dominant", "opc": "X linked dominant", "opd": "X linked recessive", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cfb1ed7d-74f6-4c36-aad3-1a8847cb52c0", "choice_type": "single"} {"question": "Pentostatin acts by inhibiting", "exp": "Ref-Katzung 10/920 Pentostatin and cilastatin are not statins i.e. these do not act by inhibiting HMG-CoA reductase. Pentostatin acts by inhibiting adenosine deaminase. It is used for the treatment of hairy cell leukemia. Drug of choice for hairy cell leukemia is cladribine.", "cop": 3, "opa": "RNA dependent DNA polymerase", "opb": "Aldolase", "opc": "Aldenosine deaminase", "opd": "Adenylyl cyclase", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "99f4054f-de69-4e58-b62f-e425bc11d30c", "choice_type": "single"} {"question": "Minor duodenal papilla is opening of", "exp": "Minor duodenal papilla is the opening of the accessory pancreatic duct into the decending second section of the duodenum.It is situated 2cm proximal to the major duodenal papilla.and thus 5-8cm from the opening of pylorus. ref - BDC 6e vol2 pancreas imageref- netter atlas", "cop": 3, "opa": "Hepatic duct", "opb": "Hepatopancreatic duct", "opc": "Accessory pancreatic ampulla", "opd": "Bile duct", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "de62bae1-c1c3-400c-b233-617418eaf3a1", "choice_type": "single"} {"question": "Most dangerous paicles causing pneumoconiosis are of size", "exp": "In pneumoconiosis, the most dangerous paicles range from 1-5 micron in diameter, because they may reach the terminal small airway and settle in there lining notes The solubility and cytotoxicity of paicles ,modify the nature of pulmonary response", "cop": 1, "opa": "A. 1-5 micron", "opb": "B. <1 micron", "opc": "C. 5-15 micron", "opd": "D. 10-20 micron", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "418561b6-f3f8-426e-8516-cb4104e280fb", "choice_type": "single"} {"question": "Veebral level of body of sternum is", "exp": "Veebrae level of body of sternum is T5-T9. Ref - medscape.com", "cop": 4, "opa": "T3 to T4", "opb": "T4 to T5", "opc": "T5 to T7", "opd": "T5 to T9", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "348d90b3-ad84-49de-a9c2-167ee36a56b2", "choice_type": "single"} {"question": "Fast fatigable motor unit recruited", "exp": "Motor UnitEach single motor neuron and the muscle fibers it innervates constitute a motor unit.Each spinal motor neuron innervates only one kind of muscle fiber so that all the muscle fibers in a motor unit are of the same type.On the basis of the type of muscle fibers they innervate, and thus on the basis of the duration of their twitch contraction, motor units are divided into S (slow), FR (fast, resistant to fatigue), and FF (fast fatigable) units.(Refer: Table 17)(Refer: Ganong&;s Review of Medical physiology 24th edition, pg no: 108-109)", "cop": 2, "opa": "First", "opb": "Last", "opc": "During active pa of contraction", "opd": "During relaxation", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "7c52636d-85fc-4920-9317-dd75a8d13ed6", "choice_type": "single"} {"question": "Most common cause of cholangitis", "exp": "Cholangitis Ascending bacterial infection of the biliary ductal system with obstruction Most common cause of acute cholangitis is choledocholithiasis Most common organism present in the bile in patients with cholangitis : E.coli, Klebsiella pneumoniae, streptococcus faecalis & Bacteroides fragilis Etiology Choledocholithiasis(MC) Benign strictures Biliary enteric anastomotic strictures Cholangiocarcinoma and periampullary cancer Ref: Sabiston 20th edition Pgno :1507", "cop": 2, "opa": "Viral infection", "opb": "CBD stone", "opc": "Surgery", "opd": "Amoebic infection", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6a91a14b-a3e5-4ad0-9389-70ae6c4d6690", "choice_type": "single"} {"question": "Two internal cerebral veins fuse to form", "exp": "The two internal cerebral veins unite together beneath the splenium of corpus callosum to form the great cerebral vein(of GALEN).*After a sho backward course, it joins the Inferior sagittal sinus to form the straight sinus.The tributaries are :Internal cerebral veinsBasal veinsVeins from colliculiVeins from cerebellum and adjoining pas of occipital lobe(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg-181)", "cop": 3, "opa": "Middle cerebral vein", "opb": "Anterior cerebral vein", "opc": "Great cerebral vein", "opd": "Inferior cerebral vein", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "091db65b-2e84-46a2-94a0-d5c3b69af651", "choice_type": "single"} {"question": "Characteristic of acute inflammation is", "exp": "Ref Robbins 8/e p 45 ,9/e p74 The acute inflammatory response rapidly delivers leuko- cytes and plasma proteins to sites of injury. Once there, leukocytes clear the invaders and begin the process of digesting and getting rid of necrotic tissues. Acute inflammation has two major components (Fig. 2-2): * Vascular changes: alterations in vessel caliber resulting in increased blood flow (vasodilation) and changes in the vessel wall that permit plasma proteins to leave the cir- culation (increased vascular permeability). In addition, endothelial cells are activated, resulting in increased adhesion of leukocytes and migration of the leukocytes through the vessel wall. * Cellular events: emigration of the leukocytes from the circulation and accumulation in the focus of injury (cel- lular recruitment), followed by activation of the leuko- cytes, enabling them to eliminate the offending agent. The principal leukocytes in acute inflammation are neu- trophils (polymorphonuclear leukocytes). Stimuli for Acute Inflammation Acute inflammatory reactions may be triggered by a variety of stimuli: * Infections (bacterial, viral, fungal, parasitic) are among the most common and medically impoant causes of inflammation. * Trauma (blunt and penetrating) and various physical and chemical agents (e.g., thermal injury, such as burns or frostbite; irradiation; toxicity from ceain environ- mental chemicals) injure host cells and elicit inflamma- tory reactions. * Tissue necrosis (from any cause), including ischemia (as in a myocardial infarct) and physical and chemical injury * Foreign bodies (splinters, di, sutures, crystal deposits * Immune reactions (also called hypersensitivity reactions) against environmental substances or against \"self\" tissues. Because the stimuli for these inflammatory responses often cannot be eliminated or avoided, such reactions tend to persist, with features of chronic inflam- mation. The term \"immune-mediated inflammatory disease\" is sometimes used to refer to this group of disorders. Although each of these stimuli may induce reactions with some distinctive characteristics, in general, all inflamma- tory reactions have the same basic features. In this section, we describe first how inflammatory stimuli are recognized by the host, then the typical reac- tions of acute inflammation and its morphologic features, and finally the chemical mediators responsible for these reactions.", "cop": 1, "opa": "Vasodilation and increase permeability", "opb": "Vasoconstriction", "opc": "Platelet aggregation", "opd": "Infiltration by neutrophil", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "aeacc5a4-67b0-4ff1-8143-dc8c8d92b855", "choice_type": "single"} {"question": "Marker for granulocytic sarcoma", "exp": ".", "cop": 3, "opa": "CD33", "opb": "CD38", "opc": "CD117", "opd": "CD137", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "32d6f403-1fc2-434b-a4f0-faf439c163e0", "choice_type": "single"} {"question": "The largest synovial joint in the body is", "exp": "(C) Knee joint # Synovial joints (or diarthroses, or diarthroidal joints); are the most common and most moveable type of joints in the body.> As with all other joints in the body, synovial joints achieve movement at the point of contact of the articulating bones.> Structural and functional differences distinguish the synovial joints from the two other types of joints in the body, with the main structural difference being the existence of a cavity between the articulating bones and the occupation of a fluid in that cavity which a ds movement.", "cop": 3, "opa": "Shoulder joint", "opb": "Hip joint", "opc": "Knee joint", "opd": "Ankle joint", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "63d0ccd8-2e97-4d4a-8117-7d1f56c77421", "choice_type": "single"} {"question": "Most prominent spinous process is of", "exp": "The 7th cervical (C7) veebra is the largest cervical veebra the C7 has a large spinous process that protrudes posteriorly toward the skin at the back of the neck. This spinous process can be easily seen and felt at the base of the neck, making it a prominent landmark of the skeleton and giving the C7 the name veebra prominens Description BD CHAURASIA S HUMAN ANATOMY Vol 3", "cop": 4, "opa": "C2", "opb": "C5", "opc": "C6", "opd": "C7", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "ef605ebf-0bc1-4088-addf-015326c23b83", "choice_type": "single"} {"question": "Most common organ involved in retroperitoneal fibrosis", "exp": "The most impoant clinical aspect of retroperitoneal fibrosis is that the fibrotic process frequently entraps and constricts the ureters thereby causing obstructive uropathy. Retroperitoneal fibrosis - It is a nonspecific, nonsuppurative inflammation of fibro-adipose tissue of unknown cause that produces symptoms by the gradual compression of tubular structures in retroperitoneal space. Aetiology of retroperitoneal fibrosis - About 2/3rd cases are primary idiopathic, are also known as Ormond's disease Secondary Retroperitoneal fibrosis a variety of inflammatory conditions - chronic pancreatitis, histoplasmosis, tuberculosis, or actinomycosis. drugs methysergide (most imp.) b blockers hydralazine a methyldopa Etacapone (used in the t/t of Parkinson's ds.) - malignancies (prostate, non-Hodgkin's lymphoma, sarcoma, characinoid & gastric cancer). antoimmune disorders (ankylosing spondylitis, SLE PAN etc.) Symptoms of retroperitoneal fibrosis - It is more common in men between 40-60 yrs of age Early symptoms are nonspecific and vague. These are Pain - Dull noncolicky and insidious in onset. Anorexia, nausea General malaise, diarrhea Later on, symptoms result from compression of tubular retroperitoneal structures. The major structure involved are- Ureter - Most commonly involved Aoa Inferior venacava Symptoms due to the involvement of ureter (usually b/1 involvement) Dysuria Frequency of urination Chills and fever occur with secondary infection of a hydronephrotic kidney. Hematuria can occur. Diagnosis The diagnosis of retroperitoneal fibrosis usually can be made accurately by intravenous pyelography if uremia is not present. The characteristic finding on pyelogram are Hydronephrosis with a dilated touous upper ureter. Medial detion of the ureter Extrinsic ureteral compression Note: In a retroperitoneal tumor, ureter is laterally deted while in retroperitoneal fibrosis ureter medially detes. Currently, the imaging procedure of choice is the CT scan. But if renal function is compromised contrast agents are not given and then MRI is the procedure of choice. T/T of Retroperitoneal fibrosis Coicosteroids, with or without surgery, are the mainstay of medical therapy. Surgical treatment is required in patients who present with moderate or massive hydronephrosis. It consists primarily of ureterolysis (freeing the ureter from adhesions and surrounding tissue) or ureteral stenting.. Also, know Paial or complete ureteral obstruction occurs in 75 to 85% of patients. Most common site of urethral obstruction is lower third of the ureter. Ref : Love & Bailey 25/e p1007", "cop": 1, "opa": "Ureter", "opb": "Aoa", "opc": "Inferior venacava", "opd": "Sympathetic nerve plexus", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5769448c-a63e-4495-b165-680559757f9b", "choice_type": "single"} {"question": "The most common site for intestinal TB is", "exp": "Most common sites - Distal ileum and caecum Ref : Sabiston 20th edition Pgno : 1217", "cop": 1, "opa": "Distal ileum", "opb": "Jejunum", "opc": "Sigmoid colon", "opd": "Ascending colon", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "98d523aa-16bb-42c4-ad2c-83390fa288f3", "choice_type": "single"} {"question": "A 50year old male presents with pain upper abdomen, Pruritus, jaundice and weight loss, elevated ANA, the likely diagnosis is", "exp": "Clinical features More common in males, mean age at presentation is 40-45 years. About 75% of patients are symptomatic at presentation with evidence of cholestatic liver disease such as jaundice, Pruritus and fatigue Symptoms of bacterial cholangitis are uncommon. Condition is characterized by relapses & remissions with quiescent periods. Median survival from the time of diagnosis ranges from 10 to 12 years Ref: Sabiston 20th edition Pgno : 1508-1509", "cop": 1, "opa": "Primary sclerosing cholangitis", "opb": "Klatskin tumor", "opc": "Secondary sclerosing cholangitis", "opd": "Choledocholithiasis", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "4dc418ec-3643-4f7c-9aee-cf242be5d997", "choice_type": "single"} {"question": "Most common symptom of Wernicke's encephalopathy", "exp": "Wernickes encephalopathyis a triad of GLOBAL CONFUSION, OPHTHALMOPLEGIA AND ATAXIA It is due to deficiency of thiamine It is 100% reversible Most impoant symptom needed for the diagnosis is confusion If the patients wernickes encephalopathy is not trated it would result in koraskoff's psychosis koraskoff's psychosis is a misnomer it is associated with confabulation that is fluent plausible lying, where the patient fills up with memory gaps with information and she is not aware that wat is she is saying is not truth Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition,625", "cop": 1, "opa": "Confusion", "opb": "Ocular changes", "opc": "Ataxia", "opd": "Hypothermia", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "5d519d55-3069-4bcd-be3b-b50efb486d71", "choice_type": "single"} {"question": "The commonest cause of acute pancreatitis", "exp": "Causes of Acute pancreatitis Common causes Gallstones including microlithiasis (most common) Alcohol (2nd most common) Hyperglyceridemia ERCP Blunt abdominal trauma Post operative Drugs Sphincter of oddi dysfunction Rare causes Infections (CMV, Coxsackie, Mumps, Echovirus (CME) parasites) Autoimmune (sjogren syndrome) Uncommon causes Vascular causes and Vasculitis (ischaemic hypoperfusion states after Cardiac surgery) Connective tissue disorders TTP CA pancreas Hypercalcemia(Hyperparathyroidism) Periampullary Diveiculum Pancreas divisum Hereditary pancreatitis Cystic fibrosis Renal failure Ref: Sabiston 20th edition Pgno :1525-1526th edition", "cop": 1, "opa": "Biliary calculi", "opb": "Alcohol abuse", "opc": "Infective", "opd": "Idiopathic", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "9e27f7c5-9cc1-4840-96f2-673837c5db8e", "choice_type": "single"} {"question": "Commonest sign of aspiration pneumonitis is", "exp": "The patient becomes tachypneic, hypoxic, and febrile. The leukocyte count may rise, and the chest x-ray may evolve from normal to a complete bilateral \"whiteout\" within 8-24 h. Sputum pro-duction is minimal. The pulmonary signs and symptoms can resolve quickly with symptom-based therapy or can culminate in respiratory failure, with the subsequent development of bacterial superinfection over a period of days. Aspiration of gastric acid causes a chemical pneumonitis which has also been .Findings on physical examination may include tachypnea. Ref Davidson edition23rd pg 589", "cop": 2, "opa": "Cyanosis", "opb": "Tachypnea", "opc": "Crepitations", "opd": "Rhonchi", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "72c7f8b5-9dcf-4465-b9ce-f73b6685f0fb", "choice_type": "single"} {"question": "Grievous hu deals under", "exp": "Injuries are grievous, Those that endangers life Those that cause severe bodily pain for 20 days. Those that disable the sufferer from following his ordinary pursuits for 20 days. Ref: TEXTBOOK OF FORENSIC MEDICINE AND TOXICOLOGY KRISHNAN VIJ FIFTH EDITION PAGE 209", "cop": 3, "opa": "Section 304", "opb": "Section 310", "opc": "Section 320", "opd": "Section 357", "subject_name": "Anatomy", "topic_name": "Miscellaneous", "id": "dfb8f20f-9db9-4220-9bc3-318c89496aae", "choice_type": "single"} {"question": "Flexion of metacarpophalangeal joint and extension of interphalangeal joints is major action of", "exp": "It is the action of lumbricals.The dorsal interossei abduct the fingers. the palmar interossei adduct the fingers.The FDS flexes middle phalanx at PIP joints. ref :textbook of anatomy upper limb and thorax ,vishram singh ,2nd edition ,page no.144", "cop": 3, "opa": "Palmar interossei", "opb": "Dorsal interossei", "opc": "Lumbricals", "opd": "FDS", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e04eab0d-61eb-42bd-ba9e-bd8f4f1eabc9", "choice_type": "single"} {"question": "Transition from G2 to M phase of cell cycle is controlled by", "exp": "Ref Robbins 7/e p290-291 Your Position: Cell Cycle Inhibitor Proteins Cell Cycle Inhibitor Proteins Creat Cell Cycle Inhibitor Proteins The cell cycle is the series of events which regulate the life of the cell. This regulation results from a combination of several signals from different regulatory pathways that are activated in response to specific stimuli. The cell cycle has a central role in controlling cell growth and proliferation. It frequently becomes the target of genetic alteration, the accumulation of which may lead to the deregulation of these ordered events and may be related to the onset of cancer. With the growing understanding of the impoant role of cell cycle regulation in tumor formation and apoptosis, cell cycle inhibitors have been fuher studied in the field of cancer treatment. Cyclin-dependent Kinase (CDK) Inhibitors Progression through the cell cycle is ensured by paicular protein complexes, the cyclin-dependent kinases (CDKs). The CDKs are a family of highly conserved serine/threonine kinases, which share a high homology in a paicular region. CDKs may control the cell cycle by phosphorylating different targets, which may in turn be activated or inactivated. Regulation of CDK/cyclin activity can occur through regulatory proteins, such as CDK Inhibitors (CKIs). The CKIs can inhibit the activity of CDK by associating in vivo with the CDK subunit, the cyclin or the cyclin/CDK complex. This inhibition may occur in different ways, such as inhibition of the CDK kinase activity, interference with CAK mediated CDK activation, or competition with cyclins in binding to the catalytic subunit. The inhibitory process can be carried out by one or a combination of these mechanisms. The expression of these CKIs may be induced by stimuli such as senescence, contact inhibition, extracellular anti-mitogenic factors and cell cycle checkpoints. Their role in controlling cell cycle is crucial. In several forms of cancer, CKIs such as p16 and p27 are mutated. Also, they have been found to be degraded in several types of cancer. Low levels of p27 levels are correlated with poor clinical prognosis. These inhibitors can be upregulated when required, thus blocking the activation of the CDK by a cyclin. This arrests the cell in a paicular pa of the cell cycle until conditions are such that it can continue towards proliferation or, if necessary, be steered towards cell death.", "cop": 4, "opa": "Retinoblastoma", "opb": "P53protein", "opc": "CyclinE", "opd": "Cyclin B", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "da4189fa-2dc5-4939-84f3-9c8e5108a0c7", "choice_type": "single"} {"question": "Nerve to pterygoid canal is formed from", "exp": "In the anterior pa of the foramen lacerum, the greater petrosal nerve unites with the deep petrosal nerve to form the nerve of the pterygoid canal which leaves the foramen by entering the pterygoid canal in the anterior wall of the foramen lacerum. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 1, "opa": "Deep petrosal nerve + greater petrosal nerve", "opb": "Facial nerve", "opc": "Lesser superficial petrosal nerve", "opd": "Lesser petrosal nerve", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "82068b66-3c13-4b3c-a225-71ac4ac0b3d2", "choice_type": "single"} {"question": "In brachial plexus nerve arising from root is", "exp": "Nerve to serratus anterior or long thoracic nerve arises from the nerve root of C5-C7. Injury to this nerve causes the condition called winging of scapula due to paralysis of serratus anterior muscle. B D Chaurasia 7th edition Page no: 45", "cop": 1, "opa": "Nerve to serratus anterior", "opb": "Axillary nerve", "opc": "Ulnar nerve", "opd": "Suprascapular nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "1b6cf2c7-e487-40d2-889d-a9e71edda597", "choice_type": "single"} {"question": "The inferior Laryngeal aery is a branch of", "exp": "The inferior thyroid aery arises from the thyrocervical trunk The branches of the inferior thyroid aery are the inferior laryngeal, the oesophageal, the tracheal, the ascending cervical and the pharyngeal aeries.Ref: Chaurasia; Volume III; 7th edition; Page no: 155", "cop": 1, "opa": "Inferior thyroid aery", "opb": "Superior thyroid aery", "opc": "Thyrocervical trunk", "opd": "Ascending cervical aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "74d17377-3df1-42e5-8382-22a841d2ff3a", "choice_type": "single"} {"question": "The SI unit of radiation absorbed dose is", "exp": "Ref Robbins 9/e p428 Gray is a unit that expresses the energy absorbed by the target tissue per unit mass Radiation UNITS Roentgen: Is the measurement of energy produced by Gamma or X-Ray radiation in a cubic centimeter of air. It is abbreted with the capital \"R\". One milliroentgen, abbreted \"mR\" is one-thousandth of a roentgen. One microroentgen, abbreted \"uR\" is one-millionth of a roentgen. RAD: Radiation Absorbed Dose. Original measuring unit for expressing the absorption of all types of ionizing radiation (alpha, beta, gamma, neutrons, etc) into any medium. One rad is equivalent to the absorption of 100 ergs of energy per gram of absorbing tissue. System International (SI) Units The System International (S.I. unit) units for radiation measurements are \"gray\" (Gy) and \"sive\" (Sv) for absorbed dose and equivalent dose respectively. The conversion from one system to another is simple: 1 Sv = 100 rem 1 rem = .01 Sv 1 mSv = 100 mR (mrem) 1 mR = .01 mSv 1 Gy = 100 rad 1 rad = .01 Gy 1mGy = 100 mrad 1 mrad = .01 mGy", "cop": 3, "opa": "Rad", "opb": "Becquerel", "opc": "Gray", "opd": "Sieve", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "77f2de26-ea38-42db-a774-11189668357f", "choice_type": "single"} {"question": "Most impoant blood supply to stomach is", "exp": "The greater curvature of the stomach receives its blood supply from the left gastroepiploic aery along its top edge and from the right gastroepiploic aery along its lower edge. The upper poion of the greater curvature of the stomach, along with the fundus, receives blood from the sho gastric aery. ref - BDC 6e vol2 pg 277", "cop": 1, "opa": "Left gastric aery", "opb": "Sho gastric aeries", "opc": "Left gastric aeries", "opd": "Right gastro epiploic aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "82ac5ada-3222-46d2-b511-a8f2e9ab2d74", "choice_type": "single"} {"question": "In burns least useful is", "exp": "We know that Ringer's lactate is the preferred agent during initial 24 hrs. Nasogastric intubation is done to decrease the risk of emesis and possible aspiration (as parlytic ileus develops in a pt. with significant burn) Dextran is a colloid and can be used in 2nd 24 hrs., however albumin is the preferred and most widely used colloid. Blood has also role in burn patient. The need for Blood replacement is significant in extensive burns. Besides injury to red blood cells and their decreased half-life resulting in their early destruction, many patients may be anaemic. Hence, repeated and frequent transmission to maintain a hematocrit around 35% is necessary. Ref Bailey and love 27e p625 , Srb`s manual of surgery p133", "cop": 2, "opa": "Normal saline", "opb": "Blood", "opc": "Dextran", "opd": "Ringer lactate", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6bb751f8-dfa4-4e0c-93ec-0e69682ad4be", "choice_type": "single"} {"question": "Anti Gliadin antibodies are detectable in", "exp": "The most sensitive tests are the presence of IgA antibodies to tissue transglutamaminase OT IgA or IgG antibodies to desisted gliadin **anti endomysial antibodies are highly specific but less sensitive than other antibodies", "cop": 3, "opa": "Tropical sprue", "opb": "Whipple's disease", "opc": "Celiac disease", "opd": "Intestinal lymphoma", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "09f7db03-25fc-4a0a-9b8f-b5f0dfe918cf", "choice_type": "single"} {"question": "Denominator refers to", "exp": "Bony prominence on the presenting pa is the denominator", "cop": 3, "opa": "Pa of presentation lying over the int os", "opb": "Relation of different pas of fetus to one another", "opc": "Bony fixed point of reference on presenting pa", "opd": "Pa of fetus lying in the lower segmebt of uterus", "subject_name": "Anatomy", "topic_name": "General obstetrics", "id": "7903daea-cad2-4546-bc2a-08ca27244c9d", "choice_type": "single"} {"question": "Investigation of choice for audiometric evaluation of an infant is", "exp": "BERA wavesWavesSite of generationIDistal pa of cranial nerve VIIIIIProximal pa of cranial nerve VIIIIIICochlear nucleus IVSuperior olivary complexVLateral lemniscusVI, VIIInferior colliculus (Refer: PL Dhingra, Textbook of Ear, Nose, Throat, 6thedition, pg no: 26, 27)", "cop": 4, "opa": "Pure Tone Audiometry", "opb": "High frequency Audiometry", "opc": "Tympanometry", "opd": "BERA", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0db3c192-2f9c-4206-acc0-cb53e23a3e1c", "choice_type": "single"} {"question": "Zero orded kinetics in following drug with high dose", "exp": "Zero order kinetics is seen in alcohol and theoplylline Ref-KDT 7/e p31", "cop": 4, "opa": "Phenytoin and propranolol", "opb": "Digoxin and prapranolol", "opc": "Amiloride and propranolol", "opd": "Alcohol and theoplylline", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bfb08720-dd45-42d3-a265-dbb5f902b018", "choice_type": "single"} {"question": "Esophageal opening in the diaphragm is at the level of", "exp": "Oesophagus pierces diaphragm at the level of tenth thoracic vertebrae.", "cop": 2, "opa": "T8", "opb": "T10", "opc": "T12", "opd": "T6", "subject_name": "Anatomy", "topic_name": null, "id": "08340a51-daa7-4786-843b-951e0b9e7e9c", "choice_type": "single"} {"question": "The retina is an outgrowth of the", "exp": "Ref BDC volume 3,6th edition pg 292This is the thin, delicate inner layer of the eyeball.It is continuous posteriorly with the optic nerve.The outer surface of the retina is attached to the choroid, while the inner surface is in contact with the hyaloid membrane.Opposite the entrance of the optic nerve, there is a circular area called optic disc.The retina diminishes in thickness from behind forwards and is divided into optic, ciliary, and iridial pas.", "cop": 2, "opa": "Mesencephalon", "opb": "Diencephalon", "opc": "Telencephalon", "opd": "Pons", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "ac40493c-69af-4d41-910e-74b6df4bd337", "choice_type": "single"} {"question": "Reversible loss of polarity with abnormality in size and shape of cells is known as", "exp": "Ref Robbins 7/e p273_274;9/e p271 CHARACTERISTICS OF BENIGN AND MALIGNANT NEOPLASMS Nothing is more impoant to the patient with a tumor than being told: \"It is benign.\" In general, benign tumors appear to be genetically \"simple,\" harboring fewer muta- tions than cancers, and genetically stable, changing little in genotype over time. The latter feature probably explains why benign tumors such as lipomas and leiomyomas transform to malignancies rarely, if at all. In practice, the determination of benign versus malignant is made with remarkable accuracy using long-established clinical and anatomic criteria, but some neoplasms defy easy character- ization. Ceain features may indicate innocence, and others may indicate malignancy. Such problems are not the rule, however, and there are four fundamental features by which benign and malignant tumors can be distinguished: dif- ferentiation and anaplasia, rate of growth, local invasion, and metastasis. Differentiation and Anaplasia Differentiation and anaplasia are characteristics seen only in the parenchymal cells that constitute the transformed elements of neoplasms. The differentiation of parenchymal tumor cells refers to the extent to which they resemble their normal forebears morphologically and functionally. * Benign neoplasms are composed of well-differentiated cells that closely resemble their normal counterpas. A lipoma is made up of mature fat cells laden with cytoplasmic lipid vacuoles, and a chondroma is made up of mature cailage cells that synthesize their usual cailaginous matrix--evidence of morphologic and functional differentiation. In well-differentiated benign tumors, mitoses are usually rare and are of normal configuration. * Malignant neoplasms are characterized by a wide range of parenchymal cell differentiation, from sur- prisingly well differentiated (Fig. 5-3) to completel undifferentiated. For example, well-differentiated ade- nocarcinomas of the thyroid may contain normal- appearing follicles. Such tumors sometimes may be difficult to distinguish from benign proliferations. Between the two extremes lie tumors loosely referred to as moderately well differentiated. The stroma carrying the blood supply is crucial to the growth of tumors but does not aid in the separation of benign from malignant ones. The amount of stromal connective tissue does deter- mine, however, the consistency of a neoplasm. Ceain cancers induce a dense, abundant fibrous stroma (des- moplasia), making them hard, so-called scirrhous tumors. * Malignant neoplasms that are composed of undiffer- entiated cells are said to be anaplastic. Lack of differen- tiation, or anaplasia, is considered a hallmark of malignancy. The term anaplasia literally means \"back- ward formation\"--implying dedifferentiation, or loss of the structural and functional differentiation of normal cells. It is now known, however, that at least some cancers arise from stem cells in tissues; in these tumors, failure of differentiation, rather than dedifferentiation of specialized cells, accounts for their undifferentiated appearance. Recent studies also indicate that in some cases, dedifferentiation of apparently mature cells does occur during carcinogenesis. Anaplastic cells display marked pleomorphism (i.e., variation in size and shape) (Fig. 5-4). Often the nuclei are extremely hyperchromatic (dark-staining) and large resulting in an increased nuclear-to-cytoplasmic ratio that may approach 1: 1 instead of the normal 1: 4 or 1 :6. Giant cells that are considerably larger than their neighbors may be formed and possess either one enormous nucleus or several nuclei. Anaplastic nuclei are variable and bizarre in size and shape. The chromatin is coarse and clumped, and nucle- oli may be of astounding size. More impoant, mitoses often are numerous and distinctly atypical; anarchic multi- ple spindles may produce tripolar or quadripolar mitotic figures (Fig. 5-5). Also, anaplastic cells usually fail to develop recognizable patterns of orientation to one another (i.e., they lose normal polarity). They may grow Figure 5-3 Well-differentiated squamous cell carcinoma of the skin. The tumor cells are strikingly similar to normal squamous epithelial cells, with intercellular bridges and nests of keratin (arrow). (Couesy of Dr. Trace Worrell, Depament of Pathology, University of Texas Southwestern Medical School, Dallas, Texas.) Figure 5-4 Anaplastic tumor of the skeletal muscle (rhabdomyosar- coma). Note the marked cellular and nuclear pleomorphism, hyperchro- matic nuclei, and tumor giant cells. (Couesy of Dr. Trace Worrell, Depa in sheets, with total loss of communal structures, such as glands or stratified squamous architecture. The more differentiated the tumor cell, the more com- pletely it retains the functional capabilities of its normal counterpas. Benign neoplasms and even well-differenti- ated cancers of endocrine glands frequently elaborate the hormones characteristic of their origin. Well-differentiated squamous cell carcinomas produce keratin (Fig. 5-3), just as well-differentiated hepatocellular carcinomas secrete bile. In other instances, unanticipated functions emerge. Some cancers may elaborate fetal proteins not produced by comparable cells in the adult. Cancers of nonendocrine origin may produce so-called ectopic hormones. For example, ceain lung carcinomas may produce adrenocor- ticotropic hormone (ACTH), parathyroid hormone-like hormone, insulin, glucagon, and others. More is said about these phenomena later. Despite exceptions, the more rapidly growing and the more anaplastic a tumor, the less likely it is to have specialized functional activity. Of relevance in the discussion of differentiation and ana- plasia is dysplasia, referring to disorderly but non-neoplastic proliferation. Dysplasia is encountered principally in epi- thelial lesions. It is a loss in the uniformity of individual cells and in their architectural orientation. Dysplastic cells exhibit considerable pleomorphism and often possess hyperchro- matic nuclei that are abnormally large for the size of the cell. Mitotic figures are more abundant than usual and frequently appear in abnormal locations within the epithe- lium. In dysplastic stratified squamous epithelium, mitoses are not confined to the basal layers, where they normally occur, but may be seen at all levels and even in surface cells. There is considerable architectural anarchy. For example, the usual progressive maturation of tall cells in the basal layer to flattened squames on the surface may be lost and replaced by a disordered scrambling of dark basal- appearing cells (Fig. 5-6). When dysplastic changes are marked and involve the entire thickness of the epithelium, the lesion is referred to as carcinoma in situ, a preinvasive stage of cancer (Chapter 18). Although dysplastic changes often are found adjacent to foci of malignant transforma- tion, and long-term studies of cigarette smokers show that epithelial dysplasia almost invariably antedates the appear- ance of cancer, the term dysplasia is not synonymous with cancer; mild to moderate dysplasias that do not involve the entire thickness of the epithelium sometimes regress completely, par- ticularly if inciting causes are removed.", "cop": 2, "opa": "Metaplasia", "opb": "Dysplasia", "opc": "Hyperplasia", "opd": "Anaplasia", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "4b747ae3-d083-4f16-8f2e-5d4b97377b70", "choice_type": "single"} {"question": "Most common bone to be fractured in a baby, during birth", "exp": "During birth, the most common bone to be fractured in the baby is clavicle.", "cop": 2, "opa": "Fracture humerus", "opb": "Fracture clavicle", "opc": "Fracture scapula", "opd": "Fracture femur", "subject_name": "Anatomy", "topic_name": null, "id": "3b04e339-b1c5-4b99-b77d-5405b8c4637c", "choice_type": "single"} {"question": "Common carotid aery bifurcation is at", "exp": "At the level of the upper border of the thyroid cailage, the aery ends by dividing into the external and internal carotid aeries. The right common carotid aery is a branch of the brachiocephalic aery. The left common carotid aery is branch of the arch of the aoa. Ref: BDC volume 3;sixth edition: pg 99", "cop": 1, "opa": "Thyroid cailage", "opb": "Cricord cailage", "opc": "C7", "opd": "T2", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "1b89461d-52a2-4693-b2f3-92faef389525", "choice_type": "single"} {"question": "Structures pass through optic foramen", "exp": "Optic foramen transmits Optic nerve with all layer of meninges Ophthalmic aery Fig: structures passing through various foramina of skull", "cop": 2, "opa": "Optic nerve alone", "opb": "Ophthalmic aery and optic nerve", "opc": "Ophthalmic vein and ophthalmic aery", "opd": "Optic nerve and ophthalmic vein", "subject_name": "Anatomy", "topic_name": "Cranial cavity", "id": "29ea62b6-07bf-4ec3-b75f-402b72b923c8", "choice_type": "single"} {"question": "Not a branch of celiac trunk", "exp": "(C) Superior mesenteric artery # SUPERIOR MESENTERIC ARTERY (SMA) arises from the anterior surface of the abdominal aorta, just inferior to the origin of the celiac trunk, and supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon, as well as the pancreas.> The coeliac trunk is the first anterior branch and arises just below the aortic hiatus at the level of T12/L1 vertebral bodies.> It divides into the left gastric, common hepatic and splenic arteries. The coeliac trunk may also give off one or both of the inferior phrenic arteries.", "cop": 3, "opa": "Left gastric artery", "opb": "Common hepatic artery", "opc": "Superior mesenteric artery", "opd": "Splenic artery", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "01096a74-12b5-4977-b0d1-d59fd12911fc", "choice_type": "single"} {"question": "Lymphatic drainage of upper outer quadrant of breast is", "exp": "MAMMARY GLAND:- Modified sweat gland in superficial fascia of pectoral region. Rudimentary in males. Located in superficial fascia. Extend: veically- 2nd to 6th rib Horizontally- lateral border of sternum to mid axillary line. LYMPHATIC DRAINAGE:- Lymph nodes:- 1. Axillary-anterior, posterior, central and lateral. 2. Internal mammary. 3. Supraclavicular. 4. Posterior intercostal 5. Cephalic. Lymphatics draining the breast:- 1. Superficial- drain skin of the breast except that of nipple and areola. 2. Deep-drain parenchyma of the breast , and skin of nipple and areola. 3. A plexus of lymph ceasefires deep to areola is called subareolar plexus of sappy.The subareolar plexus and most of the lymph from the breast drains into anterior group of axillary lymph nodes. Lymphatic drainage:- 1. Lateral quadrant of breast-drains into anterior axillary/ pectoral group of lymph nodes. 2. Medial quadrant- drains into Internal mammary 3. Lower and medial quadrant- communicates with subdiaphragmatic and subperitoneal lymph plexus. 4. Deep surface of breast-apical group . 5. A few lymph vessels from the breast follow the posterior intercostal aeries and drain into posterior intercostal nodes. About 75% -axillary 20%-internal mammary 5%-posterior intercostal lymph nodes. Among the axillary lymph nodes, most of lymph goes into anterior axillary and remaining into posterior and apical. The lymph from anterior and posterior groups first goes into central and lateral groups and then through them into supraclavicular nodes.Apical group of lymph nodes are terminal. Some lymph vessels from the inferomedial quadrant of breast communicates with the subperitoneal lymph plexus and carry cancer cells to it. From here cancer cells migrate transcoelomically and deposit over ovary- krukenberg&;s tumor. {Reference:vishram singh page no.48}", "cop": 1, "opa": "Anterior axillary", "opb": "Posterior axillary", "opc": "Paratracheal", "opd": "Apical", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "598bf44e-2195-4c3b-9ab1-d3b4d014160a", "choice_type": "single"} {"question": "Compression of a nerve within the carpal tunnel products inability to", "exp": "FLEXOR RETINACULUM Transverse carpal ligament. Strong fibrous band which bridges anterior concavity of carpus and conves it into osseofibrous tunnel callef carpal tunnel for the passage of flexor tendons of the digits. Rectangular.Formed due to thickening of deep fascia in front of carpal bones. Attachments: medial-pisiform , hook of hamate.Lateral-tubercle of scaphoid and crest of trapezium. Structures passing superficial to flexor retinaculum:-(medial to lateral)1. Ulnar nerve 2. Ulnar aery 3. Posterior cutaneous branch of ulnar nerve.4. Tendon of palmaris longus.5. Palmar cutaneous branch of median nerve.6. Superficial palmar branch of radial aery. Structures passing deep to flexor retinaculum:-1. Tendon of FDS2. Tendon of FDP 3. Tendon of FPL.4. median nerve. Ulnar bursa-tendons of FDS&FDP.Radial bursa- tendon of flexor pollicis Flexor carpi radialis pass through separate canal. CARPAL TUNNEL SYNDROME:-Injury to median nerve in carpal tunnel.Causes:-Tenosynovitis of flexor tendons.MyxedemaRetention of fluid in pregnancy Fracture dislocation of lunate bone.Osteoahritis of wrist. Symptoms:-1. Feeling of burning pain or \" pins & needles \" along lateral 3 and half digits especially at night.2. Weakness of thenar muscles.3. No sensory loss over thenar eminence.4. Ape thumb deformity if left untreated.5. Positive phalens abd tinel's sign.Phalen' sign-flexion of both wrists against each other for one minute reproduces the symptoms.Tinel's sign- percussion over flexor retinaculum reproduces symptoms. {Reference:vishram singh, page no.196,} mnemonic: Spm fully Boring Flexor digitorum Superficalis tendon, flexor digitorum profundus tendon, median nerve, Flexor poLLicis longus, Bursae- radial & ulnar", "cop": 1, "opa": "Abduct the thumb", "opb": "Adduct the thumb", "opc": "Flex the distal phalanx of the thumb", "opd": "Oppose the thumb", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "eb0a7e90-071d-4048-af6f-4eba529703c6", "choice_type": "single"} {"question": "Brunner's gland are found in mucosa of", "exp": "C. i.e. Duodenum", "cop": 3, "opa": "Stomach", "opb": "Colon", "opc": "Duodenum", "opd": "Esophagus", "subject_name": "Anatomy", "topic_name": null, "id": "f1f8ddcd-8aec-4a2a-853b-ee14bc3c8aea", "choice_type": "single"} {"question": "Ligamentum teres of the liver is remnant of", "exp": "Ligamentum teres is the obliterated fibrous remnant of the left umbilical vein of the fetus. It originates at the umbilicus. It passes superiorly in the free margin of the falciform ligament. From the inferior margin of the liver, it may join the left branch of the poal vein or it may be in continuity with the ligamentum venosum.", "cop": 2, "opa": "Umbilical aeries", "opb": "Left umbilical vein", "opc": "Ductus venosus", "opd": "Ductus aeriosus", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e58deb0f-dcf9-4579-a60b-e80247dd7e3a", "choice_type": "single"} {"question": "Infectious mononucleosis affects", "exp": ".", "cop": 1, "opa": "B cells", "opb": "T cells", "opc": "NK cells", "opd": "Macrophages", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "231f8ac7-28b0-4708-86b1-d46036150f52", "choice_type": "single"} {"question": "Superior parathyroid derived from", "exp": null, "cop": 4, "opa": "Mesoderm of 3rd pouch", "opb": "Endoderm of 3rd pouch", "opc": "Mesoderm of 4th pouch", "opd": "Endoderm of 4th pouch", "subject_name": "Anatomy", "topic_name": null, "id": "2544e71e-efad-48fa-949c-319474a73cbf", "choice_type": "single"} {"question": "Pericardial space is present between", "exp": "Pericardial space (pericardial cavity) lies between parietal serous pericardium and visceral serous pericardium.", "cop": 1, "opa": "Parietal and visceral pericardium", "opb": "Endocardium and pericardium", "opc": "Epicardium and pericardium", "opd": "Endocardium and epicardium", "subject_name": "Anatomy", "topic_name": null, "id": "cc31a3a5-a1be-4a72-addb-1ccdf0ae555f", "choice_type": "single"} {"question": "\"Red nucleus\" is present at", "exp": "The red nucleus is diagnostic of midbrain division at the level of the superior colliculus; it lies between the occulomotor nucleus (CN III) and the substantia nigra. fig:- crossection at the level of Superior colliculus Midbrain", "cop": 2, "opa": "Base of pons", "opb": "Midbrain, at level of superior colliculus", "opc": "Midbrain, at level of inferior colliculus", "opd": "Medial medulla", "subject_name": "Anatomy", "topic_name": "Brainstem, cerebellum and ventricles", "id": "2ac136e8-eaeb-4806-a9c3-916e1b08039c", "choice_type": "single"} {"question": "The commonest cailage to ossify is", "exp": "The epiphyseal plate (or epiphysial plate, physis, or growth plate) is a hyaline cailage plate in the metaphysis at each end of a long bone. It is the pa of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length). The plate is not only found in children and adolescents; in adults, who have stopped growing, the plate is replaced by an epiphyseal line. This replacement is known as epiphyseal closure or growth plate fusion. Complete fusion happens between ages 12-16 for girls and 14-19 for boys. Ref - Medscape.com", "cop": 1, "opa": "Hyaline", "opb": "Elastic", "opc": "Fibrous", "opd": "Fibroelastic", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "47c93086-a4ac-4763-bebf-aa01d839de83", "choice_type": "single"} {"question": "Suprapleural membrane is a remnant of", "exp": "Suprapleural membrane/ Sibson's fascia is a remnant of Scalenus minimus.", "cop": 2, "opa": "Scalenus anterior", "opb": "Scalenus minimus", "opc": "Subclavius", "opd": "Scalinus medius", "subject_name": "Anatomy", "topic_name": null, "id": "e6986baf-0f92-4d56-a5db-484a01676858", "choice_type": "single"} {"question": "A patient presents with a penetrating chest wound associated with intrathoracic haemorrhage. A thoracotomy is done by taking an incision in the 41h/51h intercostals space staing 1 cm away from the lateral margin of the sternum. This is done to avoid injury to the", "exp": "C i.e. Internal thoracic aeryIntercostal (external, internal & innermost) muscles (not transverses thoracic) are pierced in pleural taping in mild axillary line.Latissimus dorsi, serratus anterior, rhomboidus major & intercostal muscles are cut in posterolateral thoracotomy whereas pectoralis is cut in anterior & anterolateral approach.Thoracotomy in upper 6 intercostal spaces is done by taking an incision 1 cm lateral to sternum to avoid injury to internal thoracic (mammary) aeryQ.", "cop": 3, "opa": "Pleura", "opb": "Intercostal aery", "opc": "Internal thoracic aery", "opd": "Intercostal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "9355f323-6c2b-4849-baeb-b02606adf4cb", "choice_type": "single"} {"question": "Posterior boundary of Carotid Triangle is formed by", "exp": "Boundaries of carotid triangle IN FRONT & ABOVE- Post Belly of Digastric and Stylohyoid Muscle. IN FRONT & BELOW- Superior Belly of Omohyoid. BEHIND- Anterior Border of SternoCleidomastoid.", "cop": 4, "opa": "Superior belly of omohyoid", "opb": "Posterior belly of digastric", "opc": "Sterno hyoid", "opd": "Sternocleido mastoid", "subject_name": "Anatomy", "topic_name": "Neck Triangles and parotid gland", "id": "0abb1b6f-3f1a-4c22-b0f4-b9ae099f8356", "choice_type": "single"} {"question": "Initial 2cm of Duodenum does not get arterial supply by", "exp": "Initial 2cm of Duodenum ( Duodenal Cap) is not supplied by Superior pancreaticoduodinal artery.", "cop": 2, "opa": "Right gastric artery", "opb": "Superior pancreaticoduodinal artery", "opc": "Right Gastroepiploic artery", "opd": "Common hepatic artery", "subject_name": "Anatomy", "topic_name": null, "id": "88cb08a4-050b-478b-8e2e-8a65ed1264f2", "choice_type": "single"} {"question": "Winging of scapula is due to injury to", "exp": "Winging of scapula is due to the injury to long thoracic nerve(C5, C6, and C7). Long thoracic nerve supplies the serratus anterior muscle and injury to this nerve causes the prominence of interior angle and medial border of scapula. The patient is unable to perform pushing action. B D Chaurasia 7th edition Page no: 12", "cop": 1, "opa": "Long thoracic nerve", "opb": "Sho thoracic nerve", "opc": "Axillary nerve", "opd": "Suprascapular nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "806b50db-bf38-4c30-a84a-5ac8635e111d", "choice_type": "single"} {"question": "The indifferent embryo begins phenotypic sexual differentiation during", "exp": "The embryo during weeks 1-6 remains in an undifferentiated stage. The embryo begins phenotypic sexual differentiation during week 7.", "cop": 3, "opa": "Week 3 of development", "opb": "Week 5 of development", "opc": "Week 7 of development", "opd": "Week 12 of development", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "b657824b-7bdc-4189-ad5a-56940421f2c1", "choice_type": "single"} {"question": "White infract is seen in", "exp": "ref Robbins 8/e p674; 9/e p134,664-665 White infarcts occur with aerial occlusions in solid organs with end-aerial circulations (e.g., hea, spleen, and kidney), and where tissue density limits the seepage of blood from adjoining patent vascular beds (Fig. 3-17, B). Infarcts tend to be wedge-shaped, with the occluded vessel at the apex and the organ periphery forming the base (Fig. 3-17); when the base is a serosal surface, there is often an overlying fibrinous exudate. Lateral margins may be irregular, reflecting flow from adjacent vessels. The margins of acute infarcts typically are indistinct and slightly hemorrhagic; with time, the edges become better defined by a narrow rim of hyperemia attributable to inflammation. Infarcts resulting from aerial occlusions in organs without a dual circulation typically become progressively paler and sharply defined with time (Fig. 3-17, B). By comparison, hemorrhagic infarcts are the rule in the lung and other spongy organs (Fig. 3-17, A). Extravasated red cells in hemorrhagic infarcts are phagocytosed by macrophages, and the heme iron is conveed to intracellular hemosiderin.", "cop": 3, "opa": "Lung", "opb": "Intestine", "opc": "Hea", "opd": "Ovary", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5eb86f58-403e-4429-ab3f-9c0831216236", "choice_type": "single"} {"question": "The membranous labyrinth develops from", "exp": "The membranous labyrinth of the internal ear is derived from the otic vesicle The surface ectoderm on either side of the hindbraint thickens to form otic placodes. The otic placodes invaginate to form otic vesicles. The otic vesicles fuher divides into 2 components that develop into structures of the membranous labyrinth: The ventral component forms the saccule and cochlear duct The dorsal component forms the utricle, semicircular canals, endolymphatic duct. Ref: Inderbir Singh Human Embryology 11 e pg 328.", "cop": 3, "opa": "First pharyngeal pouch", "opb": "First pharyngeal cleft", "opc": "Otic vesicle", "opd": "Meckel's cailage", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "dff3fb9c-f2a7-4c63-9bdc-1d18ea79f808", "choice_type": "single"} {"question": "Costochondral joint is an example of", "exp": "Primary Cailaginous joint The bones are united by a plate of hyaline cailage so that the joint is immovable and strong These joints are tempory in nature because after a ceain age the cailaginous plate is repalced by bone (synostosis) Ref :BD CHAURASIA S Handbook of General Anatomy Fouh edition Page no 63", "cop": 2, "opa": "Fibrous joint", "opb": "Primary cailaginous joint", "opc": "Secondary cailaginous joint", "opd": "Synol joint", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "a9f1cc9a-f8e5-4179-ab2c-df18533c0c35", "choice_type": "single"} {"question": "pancreatitis is a side effect of", "exp": "LETHAL SIDE EFFECTS OF VALPROATE - Hyperammonemia - Pancreatitis - Hepatic failure - Neural tube defects - Thrombocytopenia MINOR SIDE EFFECTS OF VALPROATE - Hair loss - PCOD - WEIGHT GAIN - TREMORS Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th editiojn, pg no.935", "cop": 1, "opa": "valproate", "opb": "clonazepam", "opc": "clozapine", "opd": "amisulpride", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "56f16301-fafb-4cdd-b96a-d5ad7fad3d9a", "choice_type": "single"} {"question": "Coracoid process is", "exp": "Coracoid process is directed forwards and slightly laterally. It is bent finger like. It is atavistic type of epiphysis. B D Chaurasia 7th edition Page no : 9", "cop": 4, "opa": "Pressure epiphysis", "opb": "Traction epiphysis", "opc": "Aberrant epiphysis", "opd": "Atavistic epiphysis", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "65fa7669-e10d-4d84-9890-3672b6c7c0e6", "choice_type": "single"} {"question": "Main action of superior rectus", "exp": "Actions of superior rectus Veical axis: elevation Main action horizontal axis: addicts Anterioposterior axis: rotates medially (intorsion) Ref: BDC volume 3:sixth edition pg 211", "cop": 3, "opa": "Extorsion", "opb": "Intorsion", "opc": "Elevation", "opd": "Depression", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f8f86456-5c24-48a7-93b1-0eb3c50efdd6", "choice_type": "single"} {"question": "The classical lobute of the liver is centred around", "exp": "Inderbir Singh's Human Histology Sixth edition Pg 298 Centre of each lobule of liver is called central vein", "cop": 3, "opa": "Postal vein", "opb": "Bile duct", "opc": "Central vein", "opd": "Hepatic aery", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "6d45b175-2eca-443d-b9d1-5c032db9fcc2", "choice_type": "single"} {"question": "Broca's area is situated in", "exp": "(A) Inferior frontal gyrus[?]BROCA'S AREA (Motor Speech Area) is a section of the human brain that is involved in language processing, speech or sign production & comprehensionBroca's area is located in the opercular and triangular sections of the Inferior Frontal Gyrus of the Frontal lobe of the Cortex.Broca's & Wernicke's areas are found unilaterally in the brain (left hemisphere) dominant hemisphere.Broca's area comprises Brodmann area 44 and (according to some authorities) Brodmann area 45.Broca's Area is connected to Wernicke's area by a neural pathway called the arcuate fasciculus.Inability to speak after injury to the posterior-inferior frontal gyrus of the brain.Pierre Paul Brocahe identified this region, known as Broca's area.Difficulty in language production as Broca's aphasia, also called expressive aphasia.Broca's area is now typically defined in terms of the pars opercularis & pars triangularis of the inferior frontal gyrus.Present in left hemisphere in 90% of right handed & 70% of left handed people.Present in right hemisphere only in any of left handed peopleCEREBRAL CORTEX & CORTICAL AREAS AT A GLANCEAREALOCATIONFUNCTION* Motor area (Area 4)Precentral gyrus & anterior part of para-central lobuleVoluntary movements* Premotor area (Area 6)Posterior parts of frontal gyriVoluntary movements* Frontal eye field (8) Includes Areas 6 & 9Anterior to premotor area in posterior part of middle frontal gyrusConjugate deviation of eyes to opposite side.* Broca's speech area (Areas 44,45)Posterior part of inferior frontal gyms of dominant hemisphereControls motor element of speech.* Prefrontal cortexAnterior part of frontal gyri, orbital gyri, most of medial frontal gyms, & anterior part of cingulate gyms.Intellectual activity* Sensory Cortex (Areas 3,1,2)Post central gyms & adjoining parts of post central gyms & posterior part of para-central lobuleAppreciation of somatic sensations* Areas 39,40Inferior parietal lobule, supra marginal & angular gyri.Recognition of somatic sensory stimuli & their integration steriognosis* Primary visual area (17) Visual cortex or striate cortex (Visual-Sensory Cortex)Surrounds post calcarine sulcus.Primary visual function* Visual association cortex (18,19) (peristriate & parastriate areas) (Visual-Psychic)Occipital lobe adjacent to striate areaRecognition & integration of visual stimuli* Primary acoustic area (41) or 1st acoustic area (Al)Anterior transverse temporal gyms extending to superior temporal gymsPrimary auditory function* Auditory association area (Area 42)Posterior transverse temporal gymsIntegration of auditory stimuli with other sensory modalities.* Area 24Anterior part of cingulate gymsPulse, Respiration & B.P. control* Limbic systemHippocampus, alveus, fimbria, fornix & its termination into mamillary bodies are grouped under this systemMaintenance of normal homeostasis of body along with hypothalamus.* Second speech area of WernickeOccupies parietal area extending into temporal lobe round the posterior extremity of lateral sulcus.Second motor speech area.", "cop": 1, "opa": "Inferior frontal gyrus", "opb": "Superior temporal gyrus", "opc": "Inferior temporal gyrus", "opd": "Parietal gyrus", "subject_name": "Anatomy", "topic_name": "Neuroanatomy", "id": "c30099a5-8741-49f3-b9e6-4e7ef5bee3be", "choice_type": "single"} {"question": "Skin at the level of umbilicus is supplied by the spinal nerve", "exp": "The dermatome T10 is at the level of Umbilicus.The area of skin supplied by a dorsal root of a spinal nerve is called as \"Dermatome\".They represent specific regions of reception of sensory impulses.Reference: Chaurasia; 6th edition", "cop": 2, "opa": "T 9", "opb": "T 10", "opc": "T 11", "opd": "T 12", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "0a642e22-ff93-464f-b8fd-9ce1eec2173a", "choice_type": "single"} {"question": "Spiral aery is a branch of", "exp": "Spiral aery are small aeries which temporarly supply blood to endometrium of the uterus during the leteal phase of the menstrual cycle.The spiral aries are conveed for uteroplacental blood flow during pregnancy. imageRef - Semantischolar.org", "cop": 2, "opa": "Uterine aery", "opb": "Arcuate aery", "opc": "Vesical aery", "opd": "Ovarian aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "07d9a04b-f5ba-485c-b5ea-cadec3e13eb3", "choice_type": "single"} {"question": "Laryngeal cailage forming complete circle is", "exp": "Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition. Cricoid cailage is shaped like a ring. It encircles the larynx below the thyroid cailage. It is thicker and stronger than the thyroid cailage. The ring has a narrow anterior pa called the arch, and a broad posterior pa called the lamina. The lamina projects upwards behind the thyroid cailage and aiculates superiorly with the arytenoid cailages. The inferior cornua of the thyroid cailage aiculate with the side of the cricoid cailage at the junction of the arch and lamina.", "cop": 2, "opa": "Thyroid", "opb": "Cricoid", "opc": "Corniculate", "opd": "Arytenoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "502cffd7-05ee-4972-b9ee-a43860212ad7", "choice_type": "single"} {"question": "Largest branch of brachial plexus is", "exp": "Ans. is 'c' i.e., Radial Radial nerve is the largest branch of brachial plexus and is the continuation of posterior cord (root value C5_8 T1).", "cop": 3, "opa": "Ulnar", "opb": "Medial", "opc": "Radial", "opd": "Axillary", "subject_name": "Anatomy", "topic_name": null, "id": "aa56483d-5f5b-4416-9ae6-35ffa5a0ef96", "choice_type": "single"} {"question": "Structure passing deep to flexor retinaculum is", "exp": "The flexor retinaculum is a thickened band of deep fascia on the posteromedial aspect of ankle. The deep relations of flexor retinaculum from above downwards or medio laterally are tibialis posterior, flexor digitorum longus , posterior tibial aery , tibial nerve ,flexor hallucis longus. Reference: clinical anatomy for students a problem-solving approach, Neeta v Kulkarni, page no. 865", "cop": 1, "opa": "Post tibial aery", "opb": "Long saphenous vein", "opc": "Tibialis anterior tendon", "opd": "Peroneus teius", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "7e37b6ba-9efe-498d-9897-b66b03472fc4", "choice_type": "single"} {"question": "Beer's procedure", "exp": "Resection Procedure in Chronic Pancreatitis It is believed that Inflammatory process in the pancreatic head controls both the severity of symptoms and fuher progression of disease in remainder of the gland Pancreatic head is pacemaker of chronic pancreatitis. Because of this resection of pancreatic head has been shown to completely relieve pain of chronic pancreatitis in 70-80% patients Distal pancreatectomy is the ideal procedure for patients whose chronic pancreatitis is confined to pancreatic tail Usually, distal pancreatectomy is combined with splenectomy for technical reasons, but spleen can be preserved if its vascular supply is secure Ref: Sabiston 20th edition Pgno :1535", "cop": 1, "opa": "DPPHR", "opb": "LRLPJ", "opc": "Caudal pancreaticojejunostomy", "opd": "Longitudinal section pancreaticojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b480062c-2e78-44fd-85ab-2c5c1980c6c1", "choice_type": "single"} {"question": "Mechanism of action of nitric oxide is", "exp": "Refer kDT 7/e 568 Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO. It is one of the principal oxides of nitrogen. Nitric oxide is a free radical, i.e., it has an unpaired electron, which is sometimes denoted by a dot in its chemical formula, i.e., *NO. Nitric oxide is also a heteronuclear diatomic molecule, a historic class that drew researches which spawned early modern theories of chemical bonding.", "cop": 2, "opa": "Increase cAMP", "opb": "Increase cGMP", "opc": "Increase PGE2", "opd": "Increase PGD4", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3cf68914-b929-4835-bbc1-c43a77ba7607", "choice_type": "single"} {"question": "Highest point of iliac crest is seen at;", "exp": "Highest point of iliac crest lies at the level of the 4th lumbar veebral body (L4). Clinical significance: Site of bone marrow harvests to collect the stem cells used in bone marrow transplantation. Most ideal donor site forbone grafting when a large quantity of bone is needed. To estimate site for lumbar puncture as LP is done at the level b/w L3-L4 or b/w L4-L5 and highest point of iliac crest coincides with it.", "cop": 2, "opa": "L3", "opb": "L4", "opc": "S1", "opd": "S2", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "5d5b231c-82ea-4894-8b97-790cf030f2b8", "choice_type": "single"} {"question": "Quaer staggered arrangement is seen in", "exp": "The collagen fibres have a triple stranded,quaer staggered arrangement. This arrangement helps in mineralization Tropocollagen molecules are arranged in a \"quater-staggered array\" to form collagen fibres . Reference: Harpers illustrated biochemistry 31st edition pg 593", "cop": 4, "opa": "Immunoglobulin", "opb": "Hemoglobin", "opc": "Keratin", "opd": "Collagen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5e226a9a-62c3-410d-9232-9ef6395d89a7", "choice_type": "single"} {"question": "Branch of internal iliac aery", "exp": "Generally, the aery divides into an anterior division and a posterior division, with the posterior division giving rise to the superior gluteal, iliolumbar, and lateral sacral aeries. The rest usually arise from the anterior division. umbilical aery superior vesical aery obturator aery vaginal aery inferior vesical aery uterine aery middle rectal aery internal pudendal aery inferior gluteal aery Imageref - pubmed.com", "cop": 3, "opa": "Ovarian aery", "opb": "Testicular aery", "opc": "Superior vesicle", "opd": "Inferior epigastric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "c0d15855-f07e-495d-9b8a-7a1c9a681854", "choice_type": "single"} {"question": "Placental alkaline phosphatase is marker of", "exp": "Placental alkaline phosphatase is a marker of seminoma. Also know Gamma-glutamyl-transpeptidase is marker of - seminoma testis AFP is not produced by - seminomas and Choriocarcinomas", "cop": 4, "opa": "Theca cell tumour", "opb": "Teratoma", "opc": "Choriocarcinoma", "opd": "Seminoma", "subject_name": "Anatomy", "topic_name": "Urology", "id": "1cc80d08-ee1c-4af3-a59f-02a140f9deab", "choice_type": "single"} {"question": "Pain sensation from ethmoid sinus is transmitted through", "exp": "It is the principal nerve supplying the sensory supply to the Ethmoidal sinuses through its anterior and posterior Ethmoidal branches.", "cop": 2, "opa": "Infrachlear nerve", "opb": "Nasocilliary nerve", "opc": "Lacrimal nerve", "opd": "Frontal nerve", "subject_name": "Anatomy", "topic_name": null, "id": "0e2f29af-fe10-4cd0-b23e-c4b78f445ff1", "choice_type": "single"} {"question": "Onion peel appearance of splenic capsule is seen in", "exp": "Ref Robbins 9/e p224 In splenic involvement in SLE _splenomegaly, capsular thickeing , follicular hyperplasia,are common feature . central penicilliary aeries may show concerntric intimal and smooth muscle cell hyperplasia , producing onion skin appearance", "cop": 1, "opa": "SLE", "opb": "Scleroderma", "opc": "Rheumatoid ahritis", "opd": "Sjogern's syndrome", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e55d0442-b2c2-48b7-9952-5c00aa011b0d", "choice_type": "single"} {"question": "Joint involved in movement of head from left to right is", "exp": "* Atlanto-occipital (between skull and C1) joint permit nodding of head ( as when indicating approval or YES) and Atlanto-axial joint permits the head to be turned from side to side (as indicating disapproval or NO). * Atlantoaxial is a combination of three synol joints. The aiculation is at three places - a pair of lateral masses and a median complex (between dens of axis and anterior arch & transverse atlantal ligament) * Rotation movement takes place simultaneously at all joints and the normal range of rotation is 40 degrees. * The muscles which produce these movements are obliquus capitis inferior, rectus capitis posterior major, ipsilateral splenius capitis and contralateral sternocleidomastoid. Ref:- Gray's Anatomy 41st Edition; Pg num:- 737", "cop": 2, "opa": "Atlanto occipital", "opb": "Atlanto axial", "opc": "C2- C3 Joint", "opd": "C3- C4 Joint", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "9b29126f-44d6-43bc-bdcd-12dd496239fd", "choice_type": "single"} {"question": "Cerebellar coex contains", "exp": "Purkinje cells are large flask-shaped neurons seen in the intermediate layer of cerebellar coex. There are five types of neurons in cerebellar coex which are Purkinje cells, Granule cells, Stellate cells, Basket cells, Golgi cells. All the intrinsic neurons in the cerebellar coex are inhibitory except granule cells. (Ref: Vishram Singh textbook of clinical neuroanatomy, second edition, pg- 114)", "cop": 2, "opa": "Pyramidal cells", "opb": "Purkinje cells", "opc": "Stromal cells", "opd": "Kupffer cells", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "43e168c8-03af-4ee4-9f71-dc416fe26dac", "choice_type": "single"} {"question": "bulimia nervosa is treated with", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 1, "opa": "fluoxetine", "opb": "clozapine", "opc": "pimozide", "opd": "lurasidone", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "e4aa9149-17ca-4e70-a06c-568ed89504f2", "choice_type": "single"} {"question": "Stratified cuboidal epithelium seen in", "exp": "Stratified cuboidal epithelium is seen in large ducts of exocrine glands like sweat glands ,pancreas and salivary glands The ovarian surface epithelium, also called the germinal epithelium of Waldeyer, is a layer of simple squamous-to-cuboidal epithelial cells covering the ovary. The upper cervix (endocervix) is lined by a simple columnar epithelium that contains mucous-secreting cells. In contrast, the lower cervix (ectocervix) is lined by a stratified squamous epithelium. The transition point between these two epithelia is known as the external os. Larynx is lined by ciliated pseudostratified columnar epithelium except vocal cords (lined by stratified squamous epithelium). Inderbir Singh's textbook of Human Histology Seventh edition Pg no;48", "cop": 3, "opa": "Ovaries", "opb": "Cervix", "opc": "Sweat glands ducts", "opd": "Larynx", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "1bd29ef7-9c29-4ec1-a63d-a32ca86a2ca5", "choice_type": "single"} {"question": "Inferior olivary nucleus is present in", "exp": "The inferior olivary nucleus, a cerebellar relay nucleus, is the most prominent nucleus in the lateral medulla. Coordinate signals from the spinal cord to the cerebellum to regulate motor coordination and learning. fig:- crossection at the level of medulla(upper pa)", "cop": 4, "opa": "Base of pons", "opb": "Midbrain, at level of superior colliculus", "opc": "Midbrain, at level of inferior colliculus", "opd": "Lateral medulla", "subject_name": "Anatomy", "topic_name": "Brainstem, cerebellum and ventricles", "id": "9934b988-d862-48e7-a2d7-4253e0567231", "choice_type": "single"} {"question": "Pyogenic infection and braininfraction are associated with", "exp": "Ref, Robbins 9/ep43", "cop": 2, "opa": "Coagulative necrosis", "opb": "Liquefactive necrosis", "opc": "Caseous necrosis", "opd": "Fat necrosis", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8ea6100f-e7db-4b20-af58-edca4b5ac6ec", "choice_type": "single"} {"question": "Frey's syndrome is due to faulty regeneration of damaged nerve fibers. The sources of that injured nerve is", "exp": ".", "cop": 2, "opa": "hypoglossal nerve", "opb": "trigeminal nerve", "opc": "vagus nerve", "opd": "glossopharyngeal nerve", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "24895041-3860-43f0-bca1-367a0c9f961f", "choice_type": "single"} {"question": "Berry aneurysm of the posterior communicating aery causes compression of", "exp": "Berry aneurysm in the vicinity of posterior communicating aery can compress the third carnial nerve and cause oculomotor nerve palsy Aneurysms of superior cerebellar aery or tip of the basilar aery can also compress the oculomotor nerve and produce its palsy Berry aneurysm on the internal carotid aery (near its termination) compresses the lateral aspect of optic chiasma and hence damages the visual information from the ipsilateral nasal visual field. Ref: Gray's 39e/p-22", "cop": 2, "opa": "Optic nerve", "opb": "Oculomotor", "opc": "Trochlear nerve", "opd": "Hypophysis cerebri", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "0b0444b7-9682-4293-a0d7-ca6b9f21f2bc", "choice_type": "single"} {"question": "Pleural tapping in mid axillary line, muscle not pierced is", "exp": "D i.e. Transversus thoracis", "cop": 4, "opa": "Internal intercostals", "opb": "External intercostals", "opc": "Inner most intercostals", "opd": "Transverses thoracic", "subject_name": "Anatomy", "topic_name": null, "id": "d8f078a8-2308-4824-a240-19866b3ab6f8", "choice_type": "single"} {"question": "'Carpal tunnel syndrome' is caused by compression of", "exp": "Compression of median nerve causes motor,sensory,vasomotor and trophic symptoms in hand. Examination reveals wasting of thenar eminence, hypoaesthesia to light touch on the palmar aspect of lateral 3 1/2 digits. B D Chaurasia 7th edition Page no : 130", "cop": 1, "opa": "Median nerve", "opb": "Medial cord of brachial plexus", "opc": "Radial nerve", "opd": "Ulnar nerve", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "973734e6-eb28-45bc-b2eb-03f999640e7a", "choice_type": "single"} {"question": "Largest branch of veebral aery is", "exp": "Anterior inferior cerebellar aery is a branch of Basilar aery", "cop": 4, "opa": "Anterior spinal", "opb": "Posterior spinal", "opc": "Anterior inferior cerebellar", "opd": "Posterior inferior cerebellar", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "1fad4ee6-7929-41f5-9b11-c136bcd25a6a", "choice_type": "single"} {"question": "Aoic hiatus contains", "exp": "The aoic opening is osseoaponeurotic.It lies at the lower border of the 12 th thoracic veebra.It transmits Aoa,Thoracic duct and Azygos vein. REF.B D Chaurasia's human anatomy,Vol 2,Fifth edition.Pg 337", "cop": 3, "opa": "Left gastric vein and thoracic duct", "opb": "Thoracic duct and hemiazygos vein", "opc": "Azygos vein and thoracic duct", "opd": "Left vagus and thoracic duct", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "cdb7311e-de11-4e14-83f4-0162f04ff3bc", "choice_type": "single"} {"question": "Efferent from cerebellum is through", "exp": "The outgoing Purkinje axons constitute the sole output from the cerebellar coex and exe an inhibitory influence on intracerebellar nuclei.granule cells are the only intrinsic neurons. of cerebellum which is excitatory.(Ref: Vishram Singh textbook of clinical neuroanatomy second edition pg 116)", "cop": 3, "opa": "Granule cells", "opb": "Golgi cells", "opc": "Purkinje cells", "opd": "Basket cells", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "64eea1fd-2ddc-4254-8612-b187b3a7e22b", "choice_type": "single"} {"question": "The structure that lies lateral to distal radial tubercle is", "exp": "

MAMMARY GLAND:-Modified sweat gland in superficial fascia of pectoral region.Rudimentary in males.Located in superficial fascia.Extend: veically- 2nd to 6th ribHorizontally- lateral border of sternum to midaxillary line.LYMPHATIC DRAINAGE:-Lymph nodes:-1. Axillary-anterior, posterior, central and lateral.2. Internal mammary.3. Supraclavicular.4. Posterior intercostal 5. Cephalic.Lymphatics draining the breast:-1. Superficial- drain skin of the breast except that of nipple and areola.2. Deep-brain parenchyma of the breast, and skin of nipple and areola.3. A plexus of lymph ceasefires deep to areola is called subareolar plexus of sappy. The subareolar plexus and most of the lymph from the breast drains into anterior group of axillary lymph nodes.Lymphatic drainage:-1. Lateral quadrant of breast-drains into anterior axillary/ pectoral group of lymph nodes.2. Medial quadrant- drains into Internal mammary3. Lower and medial quadrant- communicates with subdiaphragmatic and subperitoneal lymph plexus.4. Deep surface of breast-apical group . 5. A few lymph vessels from the breast follow the posterior intercostal aeries and drain into posterior intercostal nodes.About 75% -axillary 20%-internal mammary 5%-posterior intercostal lymph nodes.Among the axillary lymph nodes, most of lymph goes into anterior axillary and remaining into posterior and apical. The lymph from anterior and posterior groups first goes into central and lateral groups and then through them into supraclavicular nodes.Apical group of lymph nodes are terminal.Some lymph vessels from the inferomedial quadrant of breast communicates with the subperitoneal lymph plexus and carry cancer cells to it. From here cancer cells migrate transcoelomically and deposit over ovary- krukenberg&;s tumor.{Reference:vishram singh page no.48}

", "cop": 2, "opa": "Extensor pollicis longus", "opb": "Extensor carpi radialis longus.", "opc": "Brachioradialis", "opd": "Extensor carpi ulnaris", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "0b7f3ff1-8bae-485b-bab5-a1e1b30e9dfe", "choice_type": "single"} {"question": "Dorsiflexiors of ankle joint", "exp": "DORSIFLEXION FOOT:- The forefoot is raised,and the angle between the front of the leg and the dorsum of the foot is diminished. The wider anterior trochlear surface of the talus fits into the lower end of narrow posterior pa of the lower end of tibia. No chance of dislocation in dorsiflexion. PLANTAR FLEXION OF FOOT:- Forefoot is depressed and the angle between leg and foot is increased. The narrow posterior pa of trochlear surface of talus loosely fits into the wider anterior pa of lower end of tibia. High heels causes plantar flexion of ankle joint and its dislocation. MUSCLES INVOLVED;- Main Accessory Dorsiflexion Tibialis anterior EDL ,EHL Peroneusteius Plantar flexion Gastrocnemius Soleus FHL FDL plantaris Tibialis posterior {Reference: BDC 6E pg no.150}", "cop": 1, "opa": "Tibialis anterior", "opb": "Peroneus longus", "opc": "Tibialis posterior", "opd": "Soleus", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "305c5427-6db5-44d7-b590-6d27e4fe8bee", "choice_type": "single"} {"question": "S1 nerve root irritation causes pain along the", "exp": "Sural nerve supplies the skin over the little toe and lateral aspect of the foot, with dermatome S1. Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 1324.", "cop": 3, "opa": "Anterior aspect of thigh", "opb": "Medial aspect of thigh", "opc": "Lateral aspect of foot", "opd": "Anteromedial aspect of leg", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "47f7d9aa-d28e-407e-97e5-3ecc8c4fcf51", "choice_type": "single"} {"question": "Ligament preventing the displacement of humerus is", "exp": "The area between the superior and middle glenohumeral ligament is a point of weakness in the capsule( foramen of Weitbrecht) which is a common site of anterior dislocation of humeral head. Reference : page no:147,BD chaurasia- upper limb& thorax, 7th edition.", "cop": 4, "opa": "Coracoclavicular", "opb": "Coracohumeral", "opc": "Coracoacromial", "opd": "Glenohumeral", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "90120236-907a-4065-8657-34da37055af5", "choice_type": "single"} {"question": "Safe strategy is for", "exp": "Ans is 'a' i.e. Trachoma 'SAFE' strategy is a WHO recommended strategy to fight trachoma.'SAFE' strategy for Trachoma It includesSurgery - first component of the strategy for correction of trichiasis and entropionAntibiotics - Zithromax (azithromycin) single dose oral medication is used (Zithromax is donated by Pfizer Inc.) Tetracycline eye ointment was used before Pfizer donated Zithromax.Face washing -breaks the cycle of reinfection and prevents transmission of disease.Environmental Improvement - Poverty and poor living conditions contribute to high rates of blinding trachoma. Environmental improvement includesavailability of improved water suppliesimproved household sanitation, particularly safe disposal of faeces.", "cop": 1, "opa": "Trachoma", "opb": "Diabetic Retinopathy", "opc": "Onchocerciasis", "opd": "Glaucoma", "subject_name": "Ophthalmology", "topic_name": "Anatomy", "id": "eb891c0b-16a6-4137-a4d4-034a1f2ee776", "choice_type": "single"} {"question": "Sperm after formation is stored in", "exp": "epididymus - The epididymis is an organ made up of highly coiled tube that act as reservoir of spermatozoa. Pas of epididymus : Its upper end is called the head. The head is enlarged and is connected to the upper pole of the testis by efferent ductules. The middle pa is called the body. The lower pa is called the tail. The head is made up of highly coiled efferent ductules. The body and tail are made up of a single duct, the duct of the epididymis which is highly coiled on itself. At the lower end of the tail this duct becomes continuous with the ductus deferens. Ref : B D Chaurasia's Human Anatomy , seventh edition ,volume 2 , pg.no. 248", "cop": 2, "opa": "Seoli cells", "opb": "Epididymis", "opc": "Rete testes", "opd": "Seminal vesicle", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "eda490aa-9dbc-4560-9821-d6cc25bc38eb", "choice_type": "single"} {"question": "Treatment of extragonadal germ cell tumour is", "exp": "Chemotherapy of extragonadal GCT utilizes BEP regimen; a combination of Bleomycin & Etoposide Cisplatin (Platinol)", "cop": 1, "opa": "Chemotherapy", "opb": "Radiotherapy", "opc": "Surgery", "opd": "Immunotherapy", "subject_name": "Anatomy", "topic_name": "Urology", "id": "4ad73523-70ad-412e-a4c2-ad5af0dd3393", "choice_type": "single"} {"question": "A posteriorly perforating ulcer in the pyloric antrum of the stomach is likely to produce initial localized peritonitis or abscess formation in the", "exp": "Stomach rupture posteriorly causes peritonitis or abcess formation in lesser sac or omental bursa whereas rupture anteriorly causes abscess formation in greater sac whereas in supine posture abcess formation occurs in pouch of Morison which is dependent pa of stomach.", "cop": 3, "opa": "Greater sac", "opb": "Right subhepatic/hepatorenal space (pouch of Morison)", "opc": "Omental bursa", "opd": "Right subphrenic space", "subject_name": "Anatomy", "topic_name": "Stomach and aerial supply of abdomen", "id": "26669fbf-21c3-4266-bb9c-33c5140e2006", "choice_type": "single"} {"question": "Antigen presenting cells are", "exp": "Ref Robbins 7/e p197 ;9/e p210 , macrophages and B lymphocytes is also the answer Professional antigen presenting cells(APCs) are immune cells that specialize in presentingan antigen to a T-cell. The main types of professional APCs are dendritic cells (DC), macrophages, and Bcells, Langerhans cells", "cop": 1, "opa": "Langerhans cells", "opb": "Macrophages", "opc": "Cytotoxic T cells", "opd": "Helper T cells", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7422c166-5b3d-4c3f-b736-871eb5d365d4", "choice_type": "single"} {"question": "Ductus deference is derived from", "exp": "Inderbir Singh&;s Human embryology Tenth edition The mesonephric ducts give rise to: Trigone of urinary bladder Posterior wall of prostatic urethra Ductus deferens Seminal vesicles Epididymis Ejaculatory ducts", "cop": 1, "opa": "Mesonephric duct", "opb": "Mullerian duct", "opc": "Paramesonephric", "opd": "Vitelline duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e3b53c3f-9b90-4636-9212-737a9fc5be06", "choice_type": "single"} {"question": "Destruction of fat in acute pancreatitis is due to", "exp": "Pathophysiology AP is the final result of abnormal pancreatic enzyme activation inside acinar cells Colocalization hypothesis: Cathepsin B-mediated intra acinar cell activation of the digestive enzymes leads to acinar cell injury and triggers an Inflammatory response Digestive enzymes are released which consists of trypsin and lipase which is responsible for the digestion of fat in acute pancreatitis Ref: Sabiston 20th edition Pgno :1524-1528", "cop": 1, "opa": "Lipase and trypsin", "opb": "Secretion", "opc": "Lipase and elastase", "opd": "Cholecystokinin and trypsin", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "7523a4f6-53d6-4edf-a86d-60b4640b907b", "choice_type": "single"} {"question": "Abductor muscle of vocal cord is", "exp": "movement and muscle: 1. elevation of larynx: thyrohyoid, mylohyoid 2. Depression of larynx: sternothyroid, sternohyoid 3. Opening inlet of larynx: thyroepiglottic 4.abductor of vocal cords: posterior cricoarytenoid only 5. Adductor of vocal cords: lateral cricoarytenoid and transverse and oblique arytenoids Ref BDC volume 3; 6th edition pg 258", "cop": 4, "opa": "Cricothyroid", "opb": "Interarytenoid", "opc": "Lateral cricoarytenoid", "opd": "Posterior cricoarytenoid", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "91dee4da-e0a9-42f5-afeb-c43ee4187cb1", "choice_type": "single"} {"question": "During week 2 of development, the embryoblast receives its nutrients", "exp": "During week 2 of development, the embryoblast receives its nutrients from endometrial blood vessels, endometrial glands, and decidual cells diffusion. Diffusion of nutrients does not pose a problem, given the small size of the blastocyst during week 2. Although the beginnings of a uteroplacental circulation are established by end of week 2, no blood vessels have yet formed in the extraembryonic mesoderm to carry nutrients directly to the embryoblast (this occurs in week 3 - day17).", "cop": 1, "opa": "Diffusion", "opb": "Osmosis", "opc": "Reverse osmosis", "opd": "Fetal capillaries", "subject_name": "Anatomy", "topic_name": "Development period- week 1,2,3,4", "id": "838c09fe-99ba-4e11-a92d-f39a79190bad", "choice_type": "single"} {"question": "Inhalational agent of choice for Pediatric Anaesthesia in a child with congenital hea disease", "exp": "Anaesthetic agent of choice in Pediatric age group Inhalational agentIV anaestheticsNM blockersIM anaestheticsSevoflurane, Nitrous oxide Thiopentone, Propofol Rocuronium, Atracurium, Mivacurium, Succinylcholine Ketamine ( Reserved drug )(Refer: Morgan's Clinical Anaesthesiology, 4th edition,pg no: 922-938)", "cop": 1, "opa": "Sevoflurane", "opb": "Isoflurane", "opc": "Halothane", "opd": "Enflurane", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "af13526a-f69f-4ba9-a717-a2449ce7d6bb", "choice_type": "single"} {"question": "anorexia nervosa management is", "exp": "Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of becoming fat * Restriction of food intake * Restricting type * Binge eating and purging type * Amenorrhea is not needed for diagnosis, previously amenorrhea is considered as a diagnostic criteria for diagnosis, in recent DSM 5 amenorrhea is considered for a diagnosis * Association= * OCD and depression * Decreased interest in sex * Complication * 7-14% moality * ECG changes * Hypokalemic alkalosis because of induced vomiting * Gastric dilation * Drugs * Cypro hepatidine * SSRI * Management * Admit in severe cases * Prevent vomiting by making restroom inaccessible for 2 hours after food intake * Avoid laxatives * Small frequent meals * Avoid refeeding syndrome Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 2, "opa": "induce refeeding syndrome", "opb": "avoid refeeding syndrome", "opc": "obsity", "opd": "metabolic syndrome", "subject_name": "Anatomy", "topic_name": "Sleep disorders and eating disorders", "id": "3cfb7ccf-e94c-4004-9210-8cd9bf1aa8c6", "choice_type": "single"} {"question": "Paial thromboplastin time correlates with", "exp": "ref Robbins 8/e p120,666 ,;7/e p 69;9/e p80 Shoened APTT demonstrates hypercoagulation and high MOPEG levels indicate increased catecholamine metabolism. A direct correlation between APTT and MOPEG was found herein, demonstrating a link between catecholamines and the process of coagulation. Catecholamines may interact with the a2-adrenergic receptors located on platelets and conve factor XII to XIIa or through the kallikrein-kinin system, they may activate factor XII. The activation of factor XII initiates the intrinsic coagulation pathway, which is monitored by APTT. It is suggested to control patients with a shoened APTT and increased sympathetic activity with the aim of preventing secondary coagulation and cardiovascular accidents by administering anti-thrombotic and anti-adrenergic agents It correlates with clotting factor 12 and function of platelet", "cop": 4, "opa": "Intrinsic and common pathway", "opb": "Extrinsic and common pathway", "opc": "Fibrinogen level", "opd": "Function of platelets", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "b9878856-5c8a-4593-a909-9d23fd438e70", "choice_type": "single"} {"question": "Longest cranial nerve is", "exp": "The word \"vagus\" means wandering in Latin. This is a very appropriate name, as the vagus nerve is the longest cranial nerve. It runs all the way from the brain stem to pa of the colon. Ref - medscape.com", "cop": 1, "opa": "Vagus", "opb": "Trigeminal", "opc": "Trochlear", "opd": "Olfactory", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "b5cfc71b-6813-41e6-aec8-850c0d7ae272", "choice_type": "single"} {"question": "Torticollis or Wryneck is due to", "exp": "It is due to spasm of the muscles supplied by spinal accessory nerve i.e. sternocleidomastoid and trapezius.", "cop": 1, "opa": "Sternocleidomastoid and trapezius", "opb": "Sternocleidomastoid and Platysma", "opc": "Trapezius and sternohyoid", "opd": "Trapezius and omohyoid", "subject_name": "Anatomy", "topic_name": null, "id": "fcd11786-88b5-4f4b-a8d8-ddf3205c9456", "choice_type": "single"} {"question": "Nucleus of oculomotor nerve is in", "exp": "The oculomotor nucleus is located in the central grey matter of midbrain at the level of superior colliculus. The oculomotor nucleus is in the ventromedial pa. The Edinger - Westphal nucleus (visceral oculomotor nucleus) is located dorsal to the rostral two-thirds of main oculomotor nucleus. (Ref: Vishram Singh textbook of clinical neuroanatomy, second edition pg-85)", "cop": 1, "opa": "Midbrain", "opb": "Pons", "opc": "Medulla", "opd": "Thalamus", "subject_name": "Anatomy", "topic_name": "Brain ", "id": "17415268-aa99-4c3b-be92-1a2b570d6666", "choice_type": "single"} {"question": "On 7th postoperative day after laparoscopic cholecystectomy, patient developed right upper abdominal pain and 10 cm*8cm collection. Treatment consists of", "exp": "Goals of therapy in Iatrogenic bile duct injury Control of infection limiting inflammation: Parenteral antibiotics Percutaneous drainage of peripoal fluid collection Clear and thorough delineation of entire biliary anatomy MRCP/PTC ERCP (especially if cystic duct stump leak suspected) Re-establishment of biliary enteric continuity Tension free, mucosa - to-mucosa anastomosis Longterm transanastomotic stents if involving bifurcation of higher Roux-en-Y hepaticojejunostomy Ref: Sabiston 20th edition Pgno :1503", "cop": 2, "opa": "Immediate laparotomy", "opb": "Percutaneous drainage", "opc": "Laparotomy and surgical exploration of bile duct and T-tube inseion", "opd": "Roux-en-Y hepaticojejunostomy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6a17d2ef-fcb5-4e36-b429-b782654e648f", "choice_type": "single"} {"question": "duration criteria for bulimia nervosa is", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 509", "cop": 1, "opa": "3 months", "opb": "5 months", "opc": "4 months", "opd": "6 months", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "7bc6dbbd-4b58-43ee-a497-7f502632f7e0", "choice_type": "single"} {"question": "Middle meningeal aery passes through", "exp": "Structures passing through foramen spinosum (MEN) -, Middle meningeal aery, Emissery vein,", "cop": 1, "opa": "Foramen spinosum", "opb": "Foramen ovale", "opc": "Foramen lacerum", "opd": "Toramen rotundum", "subject_name": "Anatomy", "topic_name": null, "id": "1378c8fc-cf6c-4e84-ae76-07f3f38b3d26", "choice_type": "single"} {"question": "Deficiency of the following vitamin is most commonly seen in sho bowel syndrome ileal resection", "exp": "If the distal 2/3rd of the ileum is including the ileocecal valve is resected, significant abnormalities of absorption of bike salts and Vitamin B12 may occur resulting in diarrhoea and anaemia. These abnormalities occur even though only 25% of total length of the small bowel is removed Proximal bowel resection is better tolerated than distal resection because the ileum can adapt and increase its absorptive capacity more efficiently than jejunum Ref: Sabiston 20th edition Pgno : 1171", "cop": 1, "opa": "Vitamin B12", "opb": "Vitamin B1", "opc": "Folic Acid", "opd": "Vitamin K", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "79fb77c8-9330-4e98-b1ce-27ee744ac4d8", "choice_type": "single"} {"question": "NOT a content of spermatic cord", "exp": "Ilio-inguinal nerve is not a content of spermatic cord. Spermatic cord contains: Testicular aery Ductus deferens Genital branch of Genito femoral nerve. Pampiniferous plexus of veins. Remains of processus vaginalis Aery to ductus deferens", "cop": 3, "opa": "Ductus deferens", "opb": "Testicular aery", "opc": "Ilio-inguinal nerve", "opd": "Genital branch of genitofemoral nerve", "subject_name": "Anatomy", "topic_name": "Abdominal wall ,Inguinal and Femoral region", "id": "71d441fa-57a5-458e-827c-b2a7a12ef4ce", "choice_type": "single"} {"question": "Exudative retinal detachment is seen in", "exp": "Retinal detachment - Separation of neurosensory retina proper from the pigmentary epitheliumRhegmatogenous RDTractional RDExudative RDMyopia Aphakia Trauma Senile posterior vitreous detachmentPost-traumatic retraction of scar tissue Proliferative diabetic retinopathy Posthemorrhagic retinitis proliferans Retinopathy of prematurity Plastic cyclitis Sickle cell retinopathy Eales diseaseSystemic diseases - toxemia of pregnancy, renal hypeension, blood dyscrasias, PAN Ocular diseases Inflammation - VKH syndrome, sympathetic ophthalmia, posterior scleritis Vascular - central serous retinopathy, Coats disease Neoplasm - malignant melanoma of choroid, retinoblastoma Sudden hypotony of the globe(Refer: AH Khurana, Comprehensive Textbook of Ophthalmology,5thedition, pg no: 295-299)", "cop": 2, "opa": "High myopia", "opb": "Preeclampsia", "opc": "Chorioretinal degeneration", "opd": "Penetrating injuries to the eye", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ef1ec7d0-a198-4fa6-acb2-928b83b73927", "choice_type": "single"} {"question": "Number of branches of the internal carotid aery in the neck is", "exp": "Unlike the external carotid aery, the internal carotid normally has no branches in the neck. Branches of the internal carotid aery Memonic: A VIP'S COMMA A: anterior choroidal aery V: Vidian aery I: inferolateral trunk P: posterior communicating aery S: superior hypophyseal aery C: caroticotympanic aery O: ophthalmic aery M: meningohypophyseal trunk M: middle cerebral aery A: anterior cerebral aery", "cop": 4, "opa": "1", "opb": "2", "opc": "3", "opd": "0", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7d93a4f5-0ec6-4d11-b8bb-926752401ebf", "choice_type": "single"} {"question": "phenelezine is a type of", "exp": "MAOI * IMPOANCE First class of antidepressant drugs that were introduced * MECHANISM There are three monoamines namely dopamine, adrenaline and serotonin. These mon amines are degraded by monoamine oxidase. MAOI inhibit this enzyme and acts increasing monoamines * DRUGS Phenelezine Tranylcipromine * USE ATYPICAL DEPRESSION, depression with reverse vegetative symptoms * SIDE EFFECTS Hypeensive crisis Cheese reaction When a patient on MAOI takes tyramine rich food like tyramine there will be increased release of monoamines. These excess monoamines cannot be degraded by MAO as it is blocked by MAOI. Thus, this may result in hypeensive crisis. Paresthesia's due to pyridoxine deficiency LIKE IPRONIAZID WEIGHT gain SEXUAL dysfunction ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, 925", "cop": 1, "opa": "MAOI", "opb": "SSRI", "opc": "NDRI", "opd": "SNRI", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "09b3a46f-0543-43e7-874f-015933810e07", "choice_type": "single"} {"question": "Intermediate filaments in epithelial cells is", "exp": "Intermediate filaments are used as tumor markers Epithelial cells:keratin Muscle cells:desnin Nucleus:lamin Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:8,9,14", "cop": 1, "opa": "Keratin", "opb": "Vimentin", "opc": "Desnin", "opd": "Lamin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "60e7a4bc-0141-4469-b875-37cbb4a20713", "choice_type": "single"} {"question": "Most common site for lymphoma in AIDS patients is", "exp": "Ref Robbins 9/e p254, 8/e p529,7/e p549 Pathogenesis of CNS Involvement The pathogenesis of the neurologic manifestations in AIDS deserves special mention because, in addition to the lymphoid system, the nervous system is a major target of HIV infection. Macrophages and cells belonging to the monocyte-macrophage lineage (microglial cells) are the predominant cell types in the brain that are infected with HIV. The virus is most likely carried into the brain by infected monocytes (thus, brain HIV isolates are almost exclusively of the R5 type). The mechanism of HIV-induced damage of the brain, however, remains obscure. Because neurons are not infected by HIV, and the extent of neuro- pathologic changes is often less than might be expected from the severity of neurologic symptoms, most expes believe that the neurologic deficit is caused indirectly by viral products and soluble factors (e.g., cytokines such as TNF) produced by macrophages and microglial cells. In addition, injury from nitric oxide induced in neuronal cells by gp41 and direct damage of neurons by soluble HIV gp120 have been postulated.", "cop": 1, "opa": "CNS lesions", "opb": "Spleen", "opc": "Thymus", "opd": "Abdomen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7db6069f-2d73-43fa-80a8-04d4c87b6c46", "choice_type": "single"} {"question": "MCH class 3 genes encodes", "exp": "Ref Robbins 9/e p194-195 Anantha Narayana 6/e p121; Harrison 17/e p2047 Class III molecules include several secreted proteins with immune functions: components of the complement system (such as C2, C4, and B factor), cytokines (such as TNF-a, LTA, and LTB), and heat shock proteins.", "cop": 2, "opa": "Complement components C3", "opb": "Tumor necrosis factor", "opc": "IL2", "opd": "Beta 2microglobulin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "689add97-8eaf-4036-a847-3526f8ec3e26", "choice_type": "single"} {"question": "Cavernous sinus thrombosis is due infection of", "exp": "Pterygoid plexus and the facial vein form the 2 major sources which carry the infections from the danger area of face to the cavernous sinus.", "cop": 1, "opa": "Pterygoid plexus", "opb": "Submental space", "opc": "Maxillary sinus", "opd": "Submandibular space", "subject_name": "Anatomy", "topic_name": null, "id": "66709279-417b-4bce-beab-d1d852649aed", "choice_type": "single"} {"question": "Consent for physical examination is given at", "exp": "Medicolegal significance of various ages 7 months- bility 1 year- infanticide 10 years- kidnapping for movable propeies 12 yrs- consent for physical examination, definitely responsible for crime. 14 yrs- employment, Indian factory act 15 yrs- intercourse by husband with wife is rape. 16 yrs- kidnapping a minor boy 18 yrs- attains majority and rights of a major, age for vote, consent for major surgery 21 yrs- impoation of foreign girl for illicit intercourse, age of marriage for male attains majority under cous Guardianship. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 95", "cop": 2, "opa": "10 yrs", "opb": "12 yrs", "opc": "14yrs", "opd": "16yrs", "subject_name": "Anatomy", "topic_name": null, "id": "c812a06f-6521-4553-b182-e7b38575e02a", "choice_type": "single"} {"question": "Locking muscle of Knee joint is", "exp": "Locking is a mechanism that allows the knee to remain in the position of full extension as in standing without much muscular effoLocking occurs as a result of medial rotation of the femur during the last stage of extension. Vastus medialis prevents lateral displacement of the patella.Reference: Chaurasia Volume II; 7th edition; Page no: 169", "cop": 2, "opa": "Vastus Lateralis", "opb": "Vastus Medialis", "opc": "Vastus Intermedius", "opd": "Rectus Femoris", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "1543aaa4-40b0-4cad-8af3-5aed242821ca", "choice_type": "single"} {"question": "Removal of acid drugs from the body is done by using", "exp": "Ref-KDT 6/e p30", "cop": 2, "opa": "Ammonium chloride", "opb": "Sodium bicarbonate", "opc": "Hydrochloric acid", "opd": "Citric acid", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "fec7f965-a2ca-4b8a-aeba-4dd401e1ff02", "choice_type": "single"} {"question": "Structures preserved in in functional neck dissection", "exp": "\"In contrast to a radical neck dissection, the internal jugular vein, the spinal accessory nerve, the cervical sensory nerves, and the sternocleidomastoid muscle are preserved unless they are adherent to or invaded by tumor\"- Schwaz Classical Radical neck dissection - It involves the removal of following structures Cervical lymphatics and lymph nodes Internal jugular vein Accessory nerve Submandibular gland Sternomastoid muscle The main disability that follows operation is the dropping of the shoulder due to paralysis of the Trapezius muscle as a consequence of excision of accessory nerve. Modified Radical Neck dissection (Functional neck dissection) - In this operation all the lymphatics and lymph nodes are removed as in radical neck dissection. The difference is that one or more of the following structures are preserved. Accessory nerve Stemocleidomastoid muscle Internal jugular vein Ref : Love & Bailey 25/e p733", "cop": 2, "opa": "Carotid aery , Vagus nerve", "opb": "Sternocleidomastoid muscle , Internal jugular vein", "opc": "Neck nodes", "opd": "Spinal accessory nerve , Submandibular salivary gland", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "32dc4dd5-67cc-44dc-ac85-cddb1100d31e", "choice_type": "single"} {"question": "Right adrenal vein drains into", "exp": "The Suprarenal veins or (Veins of Walshaw) are two in number: the right ends in the inferior vena cava. the left ends in the left renal vein. ref - BDC 6e vol2 pg328", "cop": 2, "opa": "Left renal vein", "opb": "IVC", "opc": "External iliac vein", "opd": "Internal iliac vein", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "e09c2dc9-158c-498a-b9fc-1743ed9facaf", "choice_type": "single"} {"question": "Foramen Ovale in middle cranial fossa transmits", "exp": "(B) Mandibular nerve # Foramen ovale;> Mnemonic:> At the base of the skull, the foramen ovale (skull) is in the greater wing of the sphenoid bone in the middle cranial fossa and transmits the mandibular division of the trigeminal nerve, otic ganglion, accessory meningeal artery, lesser petrosal nerve and emissary veins.", "cop": 2, "opa": "Spinal accessory nerve", "opb": "Mandibular nerve", "opc": "Middle meningeal artery", "opd": "Maxillary artery", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "c56dd042-4e55-46d8-a57a-362aa9619de4", "choice_type": "single"} {"question": "III cranial nerve supplies", "exp": "Inferior oblique is supplied by the Illrd cranial or oculomotor nerve. The inferior oblique arises from the orbital surface of the maxilla, lateral to the lacrimal groove. The muscle is situated near the anterior margin of the orbit.The inferior oblique is inseed close to the superior oblique a little below and posterior to the latter. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 2, "opa": "Superior oblique", "opb": "Inferior oblique", "opc": "Medial oblique", "opd": "Superior rectus", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "f7f63fc4-7cf2-489e-a95c-923c4f176819", "choice_type": "single"} {"question": "GLUT3 is seen in", "exp": "GLUT 3 is a protein channal for facilitated diffusion of glucose it is seen in neurons", "cop": 2, "opa": "Liver", "opb": "Neurons", "opc": "Pancreas", "opd": "Spleen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8b3de15a-3c0f-4bcd-926f-26e05ca5cbb9", "choice_type": "single"} {"question": "Cancer cells survival is enhanced by", "exp": "C is also the answer Ref Robbins 7/e p306, 274,9/e p302 Cell survival would be seen when they are prevented from apoptosis .genes that ors cells survival and protect from apoptosis are _ bcl_2 ..BCL _xl Genes that ors programmed cell death are : Bax,bad,bcl,_xl,p53", "cop": 1, "opa": "Suppression of p53 protein", "opb": "Over expressions of p53 gene", "opc": "Bcl_2", "opd": "Bax", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "769f6435-7bda-4208-8ad0-2b28c615cabd", "choice_type": "single"} {"question": "Upper covering layer of cochlear duct is", "exp": "Reissner's membrane - between Scala vestibuli & Scala media. Basilar membrane - between scala media & Scala tympani Tectorial membrane - covers the hair cells. Stria vascularis gives the endolymph which is ultrafiltrate of blood.", "cop": 4, "opa": "Basilar membrane", "opb": "Tectorial membrane", "opc": "Stria vascularis", "opd": "Vestibular membrane", "subject_name": "Anatomy", "topic_name": "JIPMER 2017", "id": "5dfd3654-148f-4c74-833c-7fbd14d5fc5a", "choice_type": "single"} {"question": "Primary sinusoidal dilatation of liver is also known as", "exp": "Peliosis hepatis is an uncommon vascular condition characterised by multiple, randomly distributed, blood-filled cavities throughout the liver. The size of the cavities usually ranges between a few millimetres and 3 cm in diameter. In the past, it was a mere histological curiosity occasionally found at autopsies, but has been increasingly recognised with wide-ranging conditions from AIDS to the use of anabolic steroids. It also occasionally affects spleen, lymph nodes, lungs, kidneys, adrenal glands, bone marrow, and other pas of gastrointestinal tract.", "cop": 2, "opa": "Hepar lobatum", "opb": "Peliosis hepatic", "opc": "Von-Meyerburg complex", "opd": "Caroli's disease", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "6abbe3eb-6d7b-40d8-ad84-42162c42f857", "choice_type": "single"} {"question": "The axillary aery is divided into three pas by", "exp": "Axillary aery is the continuation of the subclan aery. It extends from the outer border of the first rib to the lower border of the teres major muscle. It continues as the brachial aery. The pectoralis minor muscle crosses it and divides it into three pas. they are - (i) First pa, superior (proximal) to the muscle. (ii) Second pa, posterior (or deep) to the muscle. (iii) Third pa, inferior (distal) to the muscle. Ref : B D Chaurasi's Human Anatomy , seventh edition , volume 1 , pg. no., 50 ( fig. 4.6 )", "cop": 2, "opa": "Pectoralis major", "opb": "Pectoralis minor", "opc": "Teres major", "opd": "Teres minor", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "eb470ea5-60a0-4669-8f3d-ad902618e1db", "choice_type": "single"} {"question": "Venous spread in carcinoma rectum reaches to the following structure", "exp": "Venous invasion has been considered a poor prognostic factor in rectal cancer for over half a century. This term has evolved in recent years and now applies specifically to tumor invasion into extramural veins - extramural venous invasion. This distinction from intramural venous invasion is impoant as it is more clinically relevant. Extramural venous invasion can be identified by histopathology and MRI but until recently there has been a lack of consistency in definitions and detection techniques.", "cop": 3, "opa": "Spleen", "opb": "Kidney", "opc": "Liver", "opd": "Duodenum", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "3c3f134f-854d-4769-9d64-7580db7c4836", "choice_type": "single"} {"question": "Commonest presentation of primary biliary cirrhosis", "exp": "Primary biliary cirrhosis Believed to be an autoimmune etiology, leading to progressive destruction of intrahepatic bile ducts More common in females Associated with autoimmune disorders (CREST, Sicca syndrome, Autoimmune thyroiditis, Renal tubular acidosis) Clinical features Most patients are asymptomatic, pruritus the commonest and earliest symptom. Pruritus precedes jaundice in PBC, Pruritus is most bothersome in evening Jaundice, fatigue, melanosis (gradual darkening of exposed areas of skin), deficiency of aft soluble vitamins due to malabsorption Xanthomas and xanthelesmas due to protracted elevation of serum lipids Ref: Sabiston 20th edition Pgno : 639", "cop": 1, "opa": "Pruritus", "opb": "Pain", "opc": "Jaundice", "opd": "Fever", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b6e7f69f-cadf-4fe2-a77c-929a14495295", "choice_type": "single"} {"question": "Dermatome in the thumb and index finger region is supplied by", "exp": "-Thumb C6, index finger -C7 -reference: Textbook of anatomy ,Upper limb and thorax,Vishram Singh, 2nd edition, page no.85,86", "cop": 2, "opa": "C5,C6", "opb": "C6,C7", "opc": "C7,C8", "opd": "C8,T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "87c6304c-f9d3-43ee-8ec6-2d6095f3f6c3", "choice_type": "single"} {"question": "Stratified squamous epithelium is seen in", "exp": "Inderbir Singh's Human Histology Sixth edition Pg 25 Vagina is a fibromuscular the surrounded by non keratinised stratified squamous epithelium", "cop": 1, "opa": "Vagina", "opb": "Urinary blooder", "opc": "Uterus", "opd": "Cervix", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "08fa42f7-1563-430c-95c3-c203b4146e8b", "choice_type": "single"} {"question": "Parathyroid glands develop from branchial pouches", "exp": "The inferior parathyroid glands develop from endoderm of the third pharyngeal pouch\nThe superior parathyroid glands develop from endoderm of the fourth pharyngeal pouch", "cop": 1, "opa": "3rd & 4th", "opb": "1st & 2nd", "opc": "2nd & 3rd", "opd": "5th & 6th", "subject_name": "Anatomy", "topic_name": null, "id": "4298e05b-2cc4-465f-a782-519bdfa00603", "choice_type": "single"} {"question": "Baholin's gland is located in", "exp": "The Baholin's glands are two pea-sized compound racemose glands located slightly posterior and to the left and right of the opening of the vagina. They secrete mucus to lubricate the vagina and are homologous to bulbourethral glands in males. Ref - BDC 6e vol2 pg 393", "cop": 3, "opa": "Ischiorectal fossa", "opb": "Rectovesical pouch", "opc": "Superficial perineal pouch", "opd": "Deep perineal pouch", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "5afae86e-a601-4e41-9678-e2fc6edc02c5", "choice_type": "single"} {"question": "Following condition is due to deposition of", "exp": ".", "cop": 1, "opa": "Cholesterol", "opb": "Glycogen", "opc": "Water", "opd": "Calcium", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "0b185c9c-fb08-4f31-a259-efc2c83310e9", "choice_type": "single"} {"question": "The trabeculae carneae is present in", "exp": "In right ventricle,the interior of the inflowing pa shows trabeculae carneae or muscular ridges of 3 types. 1.Ridges or fixed elevations. 2.Bridges 3.Pillars or papillary muscles Ref:B D Chaurasia's human anatomy,vol.1.", "cop": 4, "opa": "Left atrium", "opb": "Left ventricle", "opc": "Right atrium", "opd": "Right ventricle", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "506d04d7-4a0a-4b25-9e79-e5d76a71694e", "choice_type": "single"} {"question": "Fluconazole is more effective than itraconazole in the following systemic fungal disease", "exp": "Ref-KDT 6/e p763,764 Fluconazole has maximum CNS penetration whereas itraconazole has limited entry in the brain. Therefore fluconazole is preferred over itraconazole for the treatment of cryptococcal meningitis. For all other conditions listed in the question, itraconazole is first choice drug.", "cop": 2, "opa": "Pulmonary histoplasmosis", "opb": "Cryptococcal meningitis", "opc": "Non-meningeal blastomycosis", "opd": "Disseminated sporotrichosis", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "1dbd66db-8ae3-4ef9-bdef-6f60e19ec843", "choice_type": "single"} {"question": "Suboxone is a combination of", "exp": "Bupenorphine (suboxone) It has paial agonist in mu receptor; thus, it has high affinity, less efficacy, slow dissociation. Thus, they have ceiling effect and hence there is no risk of respiratory depression and less chance of abuse As this drug has an increased first pass metabolism it is not given as oral route and given as sublingual route to improve absorption But some of the patients using substance rather than using it in a sublingual route they crush the drug used it as intravenous route To avoid the abuse of drug the drug was marketed as a combination of buprenorphine and naloxone which is called suboxone. If this drug suboxone is used by sublingual route the naloxone is not absorbed and buprenorphine alone is absorbed and thus it acts as detoxification regimen If suboxone is crushed and injected as IV naloxone is rapidly absorbed and acts as an opioid antagonist and results in severe withdrawal. Thus, it has a less chance of abuse and can be prescribed without license agreement Ref.kaplon and Sadock , synopsis of psychiatry, 11 th edition, pg no.660", "cop": 3, "opa": "naloxone+ naltrexone", "opb": "methadone+ buprenorphine", "opc": "naloxone+ buprenorphine", "opd": ".LAAM+ heroin", "subject_name": "Anatomy", "topic_name": "Substance abuse", "id": "0d91def1-94fb-4087-aa39-cc35189e24fd", "choice_type": "single"} {"question": "Deep ring is situated in", "exp": "INGUINAL CANAL:- Oblique intermuscular passage in the lower pa of the anterior abdominal wall.Extends from deep inguinal ring to superficial.Deep ring- oval opening in fascia transversalis. 1.25 cm above mid-inguinal point.Superficial ring: triangular gap in external oblique aponeurosis.Length: 4cmDirected downwards forwards and medially. {Reference: BDC 6E vol2 pg 213}", "cop": 3, "opa": "External oblique", "opb": "Internal oblique", "opc": "Fascialis tranversalis", "opd": "Cremasteric fascia", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "1f0c9497-07b6-4a95-89b1-afd60d6dfd6f", "choice_type": "single"} {"question": "A 32 years lady present with shoulder tip pain and diagnosis is pan coast tumour and presents with miosis. Diagnosis is", "exp": "Pan-coast tumor can cause compression of sympathetic ganglion resulting in Horner syndrome. These tumors are associated with Pancoast syndrome, characterized by pain, that may arise in shoulder / chest wall & characteristically radiates to ulnar surface of hand Features of Horner's syndrome: P - Ptosis M - Miosis E - Enophthalmos A- Anhidrosis L - Loss of ciliospinal reflex", "cop": 1, "opa": "Horner syndrome", "opb": "Thoracic outlet syndrome", "opc": "Aberrant right subclan aery", "opd": "Upper trunk of brachial plexus injury", "subject_name": "Anatomy", "topic_name": "FMGE 2019", "id": "270b845a-d114-44c1-98e8-6064c83257a1", "choice_type": "single"} {"question": "Trochlear and abducent nerve pass through", "exp": "Optic nerve runs backwards and medially, and passes through the optic canal to enter the middle cranial fossaInferior orbital fissure transmits maxillary nerve, the zygomatic nerve etc.Infraorbital foramen transmits the infraorbital nerve and vessels", "cop": 2, "opa": "Optic canal", "opb": "Superior orbital fissure", "opc": "Inferior orbital fissure", "opd": "Infraorbital foramen", "subject_name": "Anatomy", "topic_name": null, "id": "a1caf740-3a36-47ae-b768-f683d98ab19c", "choice_type": "single"} {"question": "Best test for esophageal varices is", "exp": ".", "cop": 2, "opa": "CT scan", "opb": "Gastroesophagoscopy", "opc": "Tomography", "opd": "Ultrasound", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "52631944-a70f-489a-ace4-78a45b6fd523", "choice_type": "single"} {"question": "BIRADS stage 5 is", "exp": " Source : Internet", "cop": 4, "opa": "Negative", "opb": "Probably benign", "opc": "Suspicious abnormality", "opd": "Highly suggesve of malignancy", "subject_name": "Anatomy", "topic_name": "Endocrinology and breast", "id": "cbf6a06a-e56d-439d-8edb-b67a11d3b396", "choice_type": "single"} {"question": "Superficial second degree burns heal by", "exp": "Superficial second degree burns usually heal with minimum scarring in 10-14 days unless they become infected. Second degree burns are divided into superficial and deep burns. Superficial dermal burns: Erythematous and painful, blanch to touch and often blister. They heal in 10-14 days. Deep dermal burns : Involve the reticular dermis appear more pale and mottled, donot blanch to touch, but remain painful to pinprick. They heal in 4-8 weeks.", "cop": 2, "opa": "1 week", "opb": "2 weeks", "opc": "3 weeks", "opd": "4 weeks", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "7a1a7792-bef9-4f5c-bd39-28846fefe15d", "choice_type": "single"} {"question": "Parasympathetic fibres arise from the following", "exp": "(D) Sacral# PREGANGLIONIC NEURONS (Craniosacral division) come from the brain or sacral region of the spinal cord. Also called the> They synapse on ganglia located near or in effector organs called terminal ganglia.> Autonomic nervous system represents the visceral component of the nervous system.> Autonomic nervous system is divided into three major parts: sympathetic, parasympathetic and enteric> Parasympathetic system is commonly referred to as having craniosacral outflow, which stands in contrast to the sympathetic nervous system, which is said to have thoracolumbar outflow.> Sympathetic trunks are two ganglionated nerve cords that extend on either side of the vertebral column from the cranial base to the coccyx.> Parasympathetic trunk emerge from the CNS only in cranial nerves III, VII, IX and X and in the second to fourth sacral spinal nerves.", "cop": 4, "opa": "Cervical", "opb": "Lumbar", "opc": "Coccyx", "opd": "Sacral", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "3835f116-ebbd-48c7-b04b-f9358f05a4c1", "choice_type": "single"} {"question": "Period of embryo is.", "exp": null, "cop": 1, "opa": "2-8 weeks", "opb": "7-36 weeks", "opc": "37-48 weeks", "opd": "1-2 weeks", "subject_name": "Anatomy", "topic_name": null, "id": "fe1f1aac-7700-4e19-ba68-ea570d6f2724", "choice_type": "single"} {"question": "Organ of rosenmullar is remnant of", "exp": "The epoophoron or epoophoron (also called organ of Rosenmuller or the parovarium) is a remnant of the mesonephric tubules that can be found next to the ovary and fallopian tube", "cop": 3, "opa": "Endodermal sinus", "opb": "Mulleria duct", "opc": "Mesonerphric tuble", "opd": "Paramesonephric duct", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "f49e3678-dfb9-4708-962a-98bc19f858b6", "choice_type": "single"} {"question": "Ectopic mucosa of Meckel's Diveicula is diagnosed by", "exp": "The 99mTc- peechnetate is preferentially taken up by the mucus secreting cells of the gastric mucosa and ectopic gastric tissue in the Diveicula. It is less accurate in adults because of reduced prevalence of ectopic gastric mucosa. The sensitivity and specificity can be improved by pentagastrin and glucagon or H2-receptor antagonists(cimetidine). Ref: schwaz's principle of surgery 10th edition Pgno : 1164", "cop": 1, "opa": "Tc-99m radionuclide scan", "opb": "Angiography", "opc": "CT", "opd": "Endoscopy", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "b3d4ebb7-489f-4e4c-bf33-84c6e84ee48e", "choice_type": "single"} {"question": "Ulnar nerve root is", "exp": "Root value of Ulnar Nerve - Ventral rami of C8 and T1. It also get fibres of C7 from the ventral root of median nerve. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no, 181 Fig Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no,57 (FIG. 4.14 )", "cop": 4, "opa": "C4 C5", "opb": "C5 C6", "opc": "C7 C8", "opd": "C8 T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "e82c8f20-f28e-4f31-9d82-52139baa2ab8", "choice_type": "single"} {"question": "Sho saphenous vein is a tributary of", "exp": "B. i.e. Posterior tibial vein", "cop": 2, "opa": "Lateral marginal vein", "opb": "Posterior tibial vein", "opc": "Medial marginal vein", "opd": "Dorsal venous arch", "subject_name": "Anatomy", "topic_name": null, "id": "ce8b55b8-80b3-47da-bd8b-cb02b66e1f15", "choice_type": "single"} {"question": "A positive tuberculin test is indicated by an area of induration of", "exp": "In this test 0.1 ml of PPD containing 5 TU is injected intradermally on the flexor aspect of the forearm with a tuberculin syringe, raising a wheal. The site is examined48-72 hrs later and the induration of: > 10mm: positive 6-9mm : equivocal /doubtful <5mm : negative Ref: Textbook of microbiology; Ananthanarayan and paniker's; 10th edition; Pg: 360", "cop": 3, "opa": "<5mm in diameter", "opb": "6-9mm in diameter", "opc": ">10mm in diameter", "opd": "No induration", "subject_name": "Anatomy", "topic_name": "Bacteriology", "id": "861eac2c-6b71-44f5-ae1d-c9689fd5e0a5", "choice_type": "single"} {"question": "Left anterior descending aery is a branch of", "exp": "Ascending aoa Right coronary aery Left coronary aery SA Nodal aery AV Nodal Aery Posterior Interventricular Aery (PIVA) Anterior Interventricular Aery (AIVA) OR Left anterior descending aery Circumflex Aery AIVA supplies the anterior 2/3rd of interventricular septum PIVA supplies the posterior 1/3rd of interventricular septum", "cop": 3, "opa": "Ascending aoa", "opb": "Right coronary aery", "opc": "Left coronary aery", "opd": "Circumflex aery", "subject_name": "Anatomy", "topic_name": "FMGE 2017", "id": "3eb7e883-f377-466f-9640-995b124ff411", "choice_type": "single"} {"question": "Massive transfusion can cause hemorrhage in a previously healthy adult due to", "exp": "Complications of Massive transfusion Massive transfusion cam lead to coagulapathy and metabolic complications Most common cause of death after massive transfusion : Dilutional Coagulopathy or DIC Transfusion of 15-20 units of blood components causes Dilutional thrombocytopenia After massive transfusion initially transient hyperglycemia due to glucose in preservatives leading to insulin release and causing hypoglycemia (MC) Galvimetric method of estimation of blood loss : Blood loss during operation is measured by weighing the swabs after use & subtracting the dry weight plus volume of blood collected in suction or drainage Metabolic complications of Massive transfusion General Fluid overload Hypothermia Impaired oxygen delivery capacity of Hb (decreased 2,3-DPG). Electrolyte Hyperkalemia Hypocalcemia Hypomagnesemia Metabolic alkalosis Metabolic acidosis (rare) Ref: Harrison's 19th edition Pgno :138", "cop": 1, "opa": "Dilutional thrombocytopenia", "opb": "Vitamin K deficiency", "opc": "Increased tPA", "opd": "Increased hemoglobin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9dc6c362-84c6-4ee6-b62a-5d19d1bccded", "choice_type": "single"} {"question": "Most common malignancy after cholecystectomy is of", "exp": "Bile acids can induce hyperproliferation of the intestinal mucosa a number of intracellular mechanisms Cholecystectomy, which alters the enterohepatic cycle of bile acids, has been associated with a moderately increased rise of proximal colon cancers It cannot be ruled out, however, that it is less the effect of the cholecystectomy than the impact of other, not yet identified factors in the lithogenic bile of such patients A number of cofactors have been identified that may enhance or neutralize the carcinogenic effects of bile acids, e.g., the amount of dietary fat, fibre or calcium Calcium, in fact, binds bile acids and this may reduce their negative impact Ref: Maingot 11th edition Pgno : 628", "cop": 1, "opa": "Colon", "opb": "Stomach", "opc": "Pancreas", "opd": "Ileum", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "1aef9cef-cd72-430a-9646-eecc6aceb797", "choice_type": "single"} {"question": "Placenta develops from", "exp": "Development of placenta: - Placenta has two components : Maternal & Fetal When the blastocyst attaches to uterus in endometrium, the endometrium is called as decidua which is of three types: - Decidua basalis , Decidua capsularis & Decidua parietalis. Fetus will also have some chorionic membrane developing leading to villi formation : Chorion Frondosum & Chorion laeve. Chorion laeve will disappear. Chorionic Frondosum persists & contributes to placenta along with Decidua Basalis .", "cop": 3, "opa": "Decidua capsularis and Chorion frondosum", "opb": "Decidua capsularis and Decidua basalis", "opc": "Decidua basalis and Chorion frondosum", "opd": "Decidua parietalis and Chorion frondosum", "subject_name": "Anatomy", "topic_name": "General Embryology 1", "id": "4fcc8ab1-7fd9-419b-8cde-c9eabb8a8904", "choice_type": "single"} {"question": "The kinetic energy of the body is least in one of the following phases of the walking cycle", "exp": "B. i.e. Mid stance phaseSpeed & so the kinetic energy is maximum in double suppo phase (i.e. heel strike, foot flat, toe flat) & minimum in single suppo phase (i.e. midstance, mid swing, heel off).", "cop": 2, "opa": "Heel strike", "opb": "Mid-stance", "opc": "Double suppo", "opd": "Toe-off", "subject_name": "Anatomy", "topic_name": null, "id": "6f4bb0d4-8406-4336-9b00-e45ba8f9732b", "choice_type": "single"} {"question": "Caplan syndrome is seen in", "exp": "Ref Harrison 17th/1625 Caplan syndrome is a combination of rheumatoid ahritis and pneumoconiosis that manifests as intrapulmonary nodules which appears homogeneous and well defined on chest X ray... It is also called as rheumatoid pneumoconiosis", "cop": 2, "opa": "COPD", "opb": "Pneumoconiosis", "opc": "Pulmonary odema", "opd": "Bronchial asthma", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "7560397e-d1cc-4279-a222-ff3e472c98a6", "choice_type": "single"} {"question": "Boundary of triangle of auscultation is not formed by", "exp": "Triangle of auscultation is a small triangular interval on the back of thorax bounded by: medially - lateral border of trapezoid laterally -medial border of scapula inferiorly - upper border of latissimus dorsi. The floor- 6th & 7th rib, 6th intercoastal space , rhomboid major. B D Chaurasia 7th edition Page no : 67 Figure 5.6,page no: 63 - Textbook of anatomy- upper limb & thorax - vishram singh", "cop": 1, "opa": "Serratus anterior", "opb": "Scapula", "opc": "Trapezius", "opd": "Latissimus dorsi", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "eca26c5e-1385-4d2f-9de0-eff07be517c4", "choice_type": "single"} {"question": "Raji cell assays are used to quantitate", "exp": "Ref Robbins 9/e p207 The Raji cell assay is an in vitro method for detecting complement fixing immune complexes in serum samples. The Raji cell is a lymphoblastoid cell with B-cell characteristics derived from a Burkitt's lymphoma cell line. It has low affinity Fc receptors for binding immunoglobulin and high affinity receptors for binding complement", "cop": 2, "opa": "Complement level", "opb": "Immune complexes", "opc": "T cells", "opd": "Interferon level", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "846656ad-606e-4719-9cad-8768376c6483", "choice_type": "single"} {"question": "Surface anatomy for internal jugular vein", "exp": "Internal jugular vein is marked by a broad line by joining these two points: a.The first point on the neck medial to the lobule of the ear b.The second point at the medial end of the clavicle. Ref.BDC volume 3,sixth edition pg 303", "cop": 1, "opa": "Ear lobule to medial third of clavicle", "opb": "Ear lobule to middle third of clavicle", "opc": "Ear lobule to lateral third of clavicle", "opd": "Mastoid to third of clavicle", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "da5bc049-2ca8-47cc-bb82-455172b85055", "choice_type": "single"} {"question": "A new drug is found to be highly lipid soluble. It is metabolism it is lower rate of 10% Per hour. On intravenous injection in produced general anaesthesia that lasts only for 15 minutes. The sho duration of anaesthesia is due to", "exp": "Ref-KDT 6/e p19 Highly lipid soluble drugs like thiopentone are quickly distributed to the tissue having high blood supply (like brain). If the target organ is also having high blood supply, drug action will be very quick. This is the case with general anaesthetics like thiopentone. Now, the drug will be distributed to less vascular tissues like fat and muscle. Movement of the drug outside the brain results in the termination of its action. This is called redistribution.", "cop": 4, "opa": "Metabolism of drug in liver", "opb": "High plasma protein binding of the drug", "opc": "Excretion of drug by kidney", "opd": "Redistribution", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "d47843aa-2136-4977-a171-8c4815c55084", "choice_type": "single"} {"question": "Most common indication for liver transplantation in children is", "exp": "Indication for liver transplantation in children Biliary atresia ( most common) Neonatal hepatitis Congenital hepatic fibrosis Alagille's syndrome Byler's disease Alpha-1 Antitrypsin deficiency Ref: Sabiston 20th edition Pgno : 637-638", "cop": 1, "opa": "Biliary atresia", "opb": "Indian childhood cirrhosis", "opc": "HCC", "opd": "Hepatitis C infection", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "5173aeee-ed87-4900-b2a8-a1c91da6a58b", "choice_type": "single"} {"question": "Aery forming anastomosis around surgical neck humerus", "exp": "Anterior Circumflex humeral aery and posterior Circumflex humeral aery are branches from 3rd pa of axillary aery . These two anastomose around the surgical neck of humerus . Posterior Circumflex humeral aery runs along with axillary nerve and passes through the quadrangular intermuscular space . B D Chaurasia 7th edition Page no : 53", "cop": 3, "opa": "1st pa of axillary aery", "opb": "2nd pa of axillary aery", "opc": "3rd pa of axillary aery", "opd": "Subclan aery", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "ca1da0e7-c20a-4143-9cc4-46c986b44df2", "choice_type": "single"} {"question": "Oblique cord is the modification of", "exp": "After bih, the proximal pas of the flexor digitorum profundus and flexor pollicis Longus FPL muscles were likely replaced by collagenous tissues, providing a specific type of intermuscular septum i.e., the oblique cord. Reference: Vishram Singh Anatomy; 2nd edition; Page no: 134", "cop": 1, "opa": "Flexor pollicis Longus", "opb": "Flexor Pollicis Brevis", "opc": "Supinator", "opd": "Pronator Teres", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "6a88c1d6-688b-4ada-b323-795e514865bf", "choice_type": "single"} {"question": "the mitochondrial enzyme involved in the metabolism of clopidorgel and proton pump inhibitors is", "exp": "clopidogrel and proton pump inhibitors are metabolized mainly by CYP2C19 and CYP3A4.Due to this reaason there is potential of interaction between two drugs. Ref-katzung 13/e p80", "cop": 3, "opa": "CYP 2A", "opb": "CYP 2B", "opc": "CYP 2C19", "opd": "CYP 2C20", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "94934531-8f18-44e3-bcf6-76502f6a6e7d", "choice_type": "single"} {"question": "Basal layer of cell in stratified squamous epithelium is", "exp": "C i.e. Cuboidal - Columnar", "cop": 3, "opa": "Squamous", "opb": "Transitional", "opc": "Cuboidal- columnar", "opd": "Pseudostratified", "subject_name": "Anatomy", "topic_name": null, "id": "a391a574-7445-48bb-b191-cabda0e295d7", "choice_type": "single"} {"question": "Carpal tunnel syndrome involves", "exp": "CARPAL TUNNEL SYNDROME:-\n\nInjury to median nerve in carpal tunnel.\n\nCauses:-\nTenosynovitis of flexor tendons.\nMyxedema\nRetention of fluid in pregnancy \nFracture dislocation of lunate bone.\nOsteoarthritis of wrist.\nSymptoms:-\n1. Feeling of burning pain or \" pins & needles \" along lateral 3 and half digits especially at night.\n2. Weakness of thenar muscles.\n3. No sensory loss over thenar eminence.\n4. Ape thumb deformity if left untreated.\n5. Positive phalens and tinel's sign.\nPhalen's sign-flexion of both wrists against each other for one minute reproduces the symptoms.\nTinel's sign- percussion over flexor retinaculum reproduces symptoms.", "cop": 1, "opa": "Median nerve", "opb": "Anterior interosseous nerve", "opc": "Ulnar nerve", "opd": "Radial nerve", "subject_name": "Anatomy", "topic_name": null, "id": "65e36162-8f77-4346-aec4-31e3678f70f1", "choice_type": "single"} {"question": "Clinical features of Choledochal cyst in adult are", "exp": "Choledochal cyst Cystic dilation of the biliary ducts, more common in females Clinical features. Classical triad : Pain, jaundice (intermittent) & abdominal mass(10%). Most common symptom in infants : Jaundice (in 80%) Most common symptom in patients >2 years of age : Abdominal pain. In children, the major clinical symptoms are recurrent abdominal pain (81.8%), nausea & vomiting (65.5%), mild jaundice (43.6%), an abdominal mass (29%), and fever (29%) In adults, abdominal pain (87%), and jaundice (42%), and present frequently. Less common clinical findings include nausea (29%), cholangitis (26%), pancreatitis (23%), and an abdominal mass(13%) Ref: Sabiston 20th edition Pgno :1511", "cop": 1, "opa": "Pain, lump and intermittent jaundice", "opb": "Pain, fever and intermittent jaundice", "opc": "Pain, lump and progressive jaundice", "opd": "Pain, fever and progressive jaundice", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "76ba2680-99f8-4395-8ea8-ad8200bde1d1", "choice_type": "single"} {"question": "Millenium Development Goal related to maternal health is", "exp": "Ref:Park's Textbook of Preventive and Social Medicine 25th Ed", "cop": 2, "opa": "Goal 1", "opb": "Goal 5", "opc": "Goal 3", "opd": "Goal 7", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "11728a39-40d8-47ab-8336-9a9e9f2d6d5c", "choice_type": "single"} {"question": "Ulipristal acetate is used for", "exp": "This drug is a SPRM (selective progesterone receptor modulator). It is used for emergency contraception and is the only hormonal contraception that is effective for 120 hrs. It is contraindicated in hepatic disorder and in lactational mothers. For emergency contraception. a 30 mg tablet is used within 120 hours (5 days) after an unprotected intercourse or contraceptive failure. It has been shown to prevent about 60% of expected pregnancies, and prevents more pregnancies than emergency contraception with levonorgestrel. Ulipristal acetate is used for pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age in a daily dose of a 5 mg tablet.", "cop": 3, "opa": "Breast cancer", "opb": "Endometriosis", "opc": "Emergency contraception", "opd": "AUB", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "950862f7-a707-4458-be3f-bdcbe30695b7", "choice_type": "single"} {"question": "Nerve supply of Stapedius is", "exp": "(D) 7th Cranial Nerve # The stapedius lies in a bony canal that is related to the posterior wall of the middle ear.> Stapedius is supplied by the facial nerve (VII CN).> It develops from the mesoderm of the second branchial arch.> The stapedius lies in a bony canal that is related to the posterior wall of the middle ear.> The stapedius is supplied by the facial nerve. It develops from the mesoderm of the second branchial arch.# BRANCHES OF THE FACIAL NERVE ARE:> Inside the internal acoustic meatus: Greater petrosal nerve - provides parasympathetic innervation to lacrimal gland, sphenoid sinus, frontal sinus, maxillary sinus, ethmoid sinus, nasal cavity, as well as special sensory taste fibers to the palate via the Vidian nerve. Nerve to stapedius - provides motor innervation for stapedius muscle in middle ear Chorda tympani - innervation to submandibular gland and sublingual gland and special sensory taste fibers for the anterior 2/3 of the tongue. Branch to the tympanic plexus> Outside skull (distal to stylomastoid foramen): Posterior auricular nerve - controls movements of some of the scalp muscles around the ear Branch to Posterior belly of Digastric and Stylohyoid muscle# Five major facial branches (in parotid gland) - from top to bottom:1. Temporal (frontal) branch of the facial nerve; 2. Zygomatic branch of the facial nerve; 3. Buccal branch of the facial nerve; 4. Marginal mandibular branch of the facial nerve; 5. Cervical branch of the facial nerve", "cop": 4, "opa": "2nd Cranial Nerve", "opb": "3rd Cranial Nerve", "opc": "5th Cranial Nerve", "opd": "7th Cranial Nerve", "subject_name": "Anatomy", "topic_name": "Misc.", "id": "4fb6a2cd-95a8-4fa4-949a-4b19a7b60000", "choice_type": "single"} {"question": "The root value of axillary nerve is", "exp": "axillary nerve also known as circumflex nerve - The axillary nerve is a branch of the posterior cord of the brachial plexus and the root value is C5 , C6. Axillary or circumflex nerve is an impoant nerve because it supplies the deltoid muscle which is the main abductor of the arm. Ref : B D Chaurasia's Human Anatomy , Seventh edition, volume 1 , pg. no, 75.", "cop": 1, "opa": "C5, C6", "opb": "C7, C8", "opc": "C8, T1", "opd": "C5, T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "71839d20-809b-4eb3-8554-e2544d9b3314", "choice_type": "single"} {"question": "Caranial nerve passing through foramen ovale includes", "exp": "structures passing through foramen ovale: Mandibular nerve Accessory meningeal aery Lesser petrosal nerve Emissary vein connecting cavernous sinus with pterygoid plexus. Ref BDC volume 3; 6th edition pg 56", "cop": 1, "opa": "Mandibular nerve", "opb": "Oculomotor nerves", "opc": "Greater petrosal nerve", "opd": "Sympathetic nerve fibres", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "3c1e00a7-1479-496d-bd36-584b11e736ef", "choice_type": "single"} {"question": "Direct opening in the right atrium with", "exp": "All veins of hea except the anterior cardiac veins and the venae cordis minimi drain into the coronary sinus which opens into the right atrium.The anterior cardiac veins and the venae cordis minimi open directly into the right atrium. BD CHAURASIA'S HUMAN ANATOMY .VOLUME 1.FIFTH EDITION.Page no-254", "cop": 1, "opa": "Anterior cardiac vein", "opb": "Oblique vein", "opc": "Middle cardiac vein", "opd": "Great cardiac vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "fc22a32a-9aab-4a31-a24f-d8bd7819f267", "choice_type": "single"} {"question": "Receptor seen in this region is", "exp": "Receptor Location Function 1. Meissner Dermo-epidermal junction Rapidly adapting two- point discrimination 2. Pacinian corpuscle Deeper dermis Rapidly adapting pressure & vibration 3. Ruffini Deeper dermis Slowly adapting 4. Merkel disc Basal layer of epidermis Slowly adapting light touch sensation. Reading braille - Meisner corpuscle >> Merkel disc Since the location is DE JUNCTION so the answer is Meissner corpuscle", "cop": 2, "opa": "Merkel cell", "opb": "Meissner's corpuscle", "opc": "Paccinian corpuscle", "opd": "Ruffini's receptor", "subject_name": "Anatomy", "topic_name": "Cailage,cell junction,lymphoid and integumentary system", "id": "da4e4c19-47b8-47fb-84ed-ed1b058b6ad7", "choice_type": "single"} {"question": "Hunterian perforator is at", "exp": "Ref: BD Chaurasia Human Anatomy vol 2 pg 125,127.", "cop": 2, "opa": "Upper thigh", "opb": "Mid thigh", "opc": "Lower thigh", "opd": "Knee", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "c3f82fe7-6412-4a0a-b635-0e73b73fe29a", "choice_type": "single"} {"question": "Multifocal non suppurative osteomyelitis is seen in", "exp": "SAPHO syndrome : synovitis, acne, pustulosis, palmo- plantar, hyperostosis and osteitis ref : maheswari 9th ed", "cop": 4, "opa": "infantile coical hyperostosis", "opb": "thalassemia", "opc": "salmonella infections", "opd": "SAPHO syndrome", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "6e57a16d-e0e4-4b70-a9d6-58d64ad8db48", "choice_type": "single"} {"question": "The epiglottis is derived from", "exp": "The caudal pa of the hypobranchial eminence forms the epiglottis . HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:213", "cop": 2, "opa": "3rd arch", "opb": "4th arch", "opc": "5th arch", "opd": "6th arch", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9b7af323-78cc-47b1-ba22-ae36cacf2320", "choice_type": "single"} {"question": "Blood supply of facial nerve", "exp": "D i.e. Ascending pharyngeal aery", "cop": 4, "opa": "Stylomastoid branch of facial nerve", "opb": "Facial aery", "opc": "Lingual aery", "opd": "Ascending pharyngeal aery", "subject_name": "Anatomy", "topic_name": null, "id": "b6399043-0b2f-4d97-996a-1012735c7f0d", "choice_type": "single"} {"question": "Most common complication of whipple's procedure is", "exp": "Morbidity following pancreaticoduodenectomy Delayed gastric emptying (18%) Pancreas fistula (12%) Wound infection (7%) Intra abdominal abscess (6%) Cardiac events (3%) Bile leak (2%) Overall reoperation (3%) Ref: Sabiston 20th edition Pgno :1548", "cop": 1, "opa": "Delayed gastric emptying", "opb": "Bleeding", "opc": "Exocrine insufficiency", "opd": "Anastomotic leak", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "fe907f58-cd1b-4e2c-bcb5-139a6e369084", "choice_type": "single"} {"question": "A 25 year old male was hospitalized with liver cyst due to Echinococcus granulosis.he refused to undergo surgery for removal of cyst.therefore, albendazole was used at high dose for 3months .this patient should be monitored for the toxicity to", "exp": "Ref-Katzung 10/869 Albendazole is used furlong X at high dose can lead to hepatotoxicity", "cop": 3, "opa": "Gonalds", "opb": "Kidney", "opc": "Liver", "opd": "Peripheral nerves", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "0f6d8267-4b84-4f45-ae56-aeef2190212d", "choice_type": "single"} {"question": "Schizophrenia with worst prognosis", "exp": "Order of prognosis from good to bad, catatonic->paranoid->undifferentiated->hebephrenic->simple", "cop": 3, "opa": "Catatonic", "opb": "Paranoid", "opc": "Hebephrenic", "opd": "Undifferentiated", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "bdb99281-00d9-4835-90cf-992afb0a4280", "choice_type": "single"} {"question": "for diagnosis of bulimia nervosa duration criteria is binge eating once a week for", "exp": "Bulimia nervosa * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Binge eating at least once a week for 3 months * Uses laxatives, diuretics, self-induced vomiting * Association= * Impulsive behaviors * increased interest in sex * They may be of normal weight * Less secretive * Mood disorders * Complication * Electrolyte abnormalities * Hypokalemia * Hypochloremia alkalosis * Russel's sign==== as these patients uses their fingers to be stick out in the throat and vomit, there is a lesion in meta carpo phalangeal joints. * Drugs * Carbamazepine * MAOI * SSRI Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no 509", "cop": 1, "opa": "3 months", "opb": "4 months", "opc": "6 months", "opd": "5 months", "subject_name": "Anatomy", "topic_name": "Treatment in psychiatry", "id": "ea29c3e3-9642-4408-bc33-1a9f23258251", "choice_type": "single"} {"question": "Aery/ aeries supplying occipital coex is", "exp": "A. i.e. PCA", "cop": 1, "opa": "PCA", "opb": "MCA", "opc": "MCA + PCA", "opd": "ACA", "subject_name": "Anatomy", "topic_name": null, "id": "cc4270f8-a279-48cf-8379-83388c1a91ca", "choice_type": "single"} {"question": "During cranial nerve examination, a neurologist asks her 33 year old patient to protrude his tongue. On doing so, her tongue detes to the right side. This finding results from paralysis of tongue muscle namely", "exp": "Genioglossus", "cop": 1, "opa": "Genioglossus", "opb": "Styloglossus", "opc": "Palatoglossus", "opd": "Hyoglossus", "subject_name": "Anatomy", "topic_name": null, "id": "42e7ebdd-93f5-476f-8350-757bfcce35f8", "choice_type": "single"} {"question": "In infant, bone marrow biopsy is done from", "exp": ".", "cop": 1, "opa": "Tibia", "opb": "Sternum", "opc": "Posterior superior iliac spine", "opd": "Iliac crest", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "ee6ebc94-a996-47da-8650-9f360ae0fa8f", "choice_type": "single"} {"question": "Exposure treatment in burns is done for", "exp": "There are two methods of management of the burn wound with a topical antibacterial agent Exposure therapy no dressings are applied over the wound after application of the agent. advantages are that bacterial growth is not enhanced as may be the case under a closed dressing, and the wound remains visible and readily accessible. disadvantages are increased pain and heat loss as a result of the exposed wound and an increased risk of cross-contamination. Closed method an occlusive dressing is applied over the agent and is changed twice daily. the disadvantage is the potential increase in bacterial growth if the dressing is not changed twice daily. advantages are less pain, less heat loss, and less cross-contamination. The closed method is generally preferred except for face and head where the exposure method is preferred Ref - Bailey & Love 23/e p194", "cop": 4, "opa": "Genitals", "opb": "Limbs", "opc": "Trunk", "opd": "Head and neck", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "9156303a-7a94-454f-8911-73f2a6d8dbd1", "choice_type": "single"} {"question": "Most common site for hyperophic keloid scar", "exp": "Keloids - It is a scar which shows extreme overgrowth so that scar tissues grows beyond the limits of original wounds and shows no tendency to resolve. Keloids grow on paicular sites, these are - Central chests (probably most common, not sure) Back Shoulder Earlobes Other points about Keloids & hyperophic scars Hyperophic scars (HTS) and keloids represent an overabundance of fibroplasia in the dermal healing process. They are both characterized by excessive collagen deposition versus collagen degradation. HTS rise above the skin level but stay within the confines of the original wound and often regress over time. Keloids are defined as scars that grow beyond the border of the original wound and rarely regress spontaneously. Both HTS and keloids occur after trauma to the skin, and may be tender, pruritic, and cause a burning sensation. Keloids are more prevalent among dark pigmented ethnicitics (i.e. Africans, Asians & Hispanics) HTS usually develop within 4 weeks after trauma Keloids tend to occur 3 months to years after the trauma. Ref : Bailey & Love 25/e p30", "cop": 4, "opa": "Face", "opb": "Arm", "opc": "Legs", "opd": "Pre sternal area", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "64085a99-edc8-4098-9a5e-c7bf8ab5a740", "choice_type": "single"} {"question": "Vomiting with coffee brown vomitus is seen in", "exp": "Fulminant poisoning by oxalic acid If the person is consumes large doses ie more than 20gm or more, death may occur due to circulatory collapse. There will be sour bitter taste in the mouth, a sense of constriction in the throat, epigastric pain and abdominal pain. The person will have nausea, eructation and vomiting with coffee brown vomitus. There may be severe thirst and abdomen will be tender. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 412", "cop": 1, "opa": "Oxalic acid poisoning", "opb": "Sulphuric acid poisoning", "opc": "Nitric acid poisoning", "opd": "Carbolic acid poisoning", "subject_name": "Anatomy", "topic_name": "Poisoning", "id": "15e17a2b-eafe-45a4-8443-8726b7cac598", "choice_type": "single"} {"question": "spinal nerve is related to", "exp": "The anterior primary ramus of C1 joins with hypoglossal nerve, which distributes the motor fibres to the geniohyoid and thyroid muscles. C1 is the first spinal nerve which is unique in that it contains only motor fibres.", "cop": 3, "opa": "Glossopharyngeal", "opb": "Vagus", "opc": "Hypoglossal", "opd": "Facial", "subject_name": "Anatomy", "topic_name": null, "id": "84f6769a-ecf4-4d1b-9d9e-be125fb533df", "choice_type": "single"} {"question": "Nasion lies at the junction of", "exp": "The nasion is the point where the internasal and frontonasal sutures meet. It lies a little above the floor of the depression at the root of the nose, below the glabella. Nasion is termed as the central point of the frontonasal suture. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.", "cop": 1, "opa": "Frontonasal and internasal suture", "opb": "Frontonasal and interparietal suture", "opc": "Frontonasal and frontozygomatic suture", "opd": "Frontogomatic and internasal suture", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "3f57a851-22b3-434f-b713-67933712d829", "choice_type": "single"} {"question": "Least mobile metatarsal of foot", "exp": "2nd metatarsal is longest and least mobile among all metatarsals, hence more prone for March fracture", "cop": 2, "opa": "1st metatarsal", "opb": "2nd metatarsal", "opc": "3rd metatarsal", "opd": "4th metatarsal", "subject_name": "Anatomy", "topic_name": null, "id": "2ce567d2-a49e-49e4-9100-8b3bc723e8ba", "choice_type": "single"} {"question": "The cranial nerve passing through Dorello canal is", "exp": "At petrous apex, the abducent nerve takes a sharp turn to pass through Dorello's canal beneath petrosphenoidal ligament.", "cop": 3, "opa": "4th", "opb": "5th", "opc": "6th", "opd": "7th", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b46c557b-a7ff-4ce7-9260-a396b661af1c", "choice_type": "single"} {"question": "In leucine zipper model, Leucine residue seen after every", "exp": "An a helix in which there is a periodic repeat of leucine residues at every seventh position. This occurs for eight helical turns and four leucine repeats. Similar structures have been found in a number of other proteins associated with the regulation of transcription in mammalian and yeast cells. (shown in the table below) It is thought that this structure allows two identical monomers or heterodimers (eg, Fos-Jun or Jun-Jun) to \"zip together\" in a coiled-coil and form a tight dimeric complex This protein-protein interaction may serve to enhance the association of the separate DNA binding domains with their target", "cop": 3, "opa": "3 amino acids", "opb": "6 amino acids", "opc": "7 amino acids", "opd": "12 amino acids", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "b9177bb7-4ef4-428d-8a19-b96761aa3fff", "choice_type": "single"} {"question": "Most common cause of empyema is", "exp": "Empyema thoracic is collection of pus in pleural space and is synonymous with grossly purulent exudative parapneumonic effusions. Ref Harrison 19th edition pg 951", "cop": 3, "opa": "Bronchopleural fistula", "opb": "Tubercular pneumonia", "opc": "Bacterial pneumonia", "opd": "Pleurisy", "subject_name": "Anatomy", "topic_name": "Respiratory system", "id": "a011846a-3469-4682-9266-9713e4c6538c", "choice_type": "single"} {"question": "Brachiocephalic vein is formed by", "exp": null, "cop": 1, "opa": "Internal jugular vein and suclavicular vein.", "opb": "External jugular vein and suclavicular vein.", "opc": "Internal jugular vein and retromandibular vein.", "opd": "External jugular vein and retromandibular vein.", "subject_name": "Anatomy", "topic_name": null, "id": "4a512d6d-f157-4455-83f9-97dcac583ad2", "choice_type": "single"} {"question": "After an incised wound ,new collagen fibrils are seen along with a thick layer of growing epithelium.The approximate age of the wound is", "exp": "Ref Robbins 9/e p106 Incised wound for the formation of collagen and new tissue, thick layer of epithelial ,and granulation tissue formation along with new blood vessels requires atleast 4_5 days", "cop": 1, "opa": "4-5days", "opb": "About 1week", "opc": "12-24hrs", "opd": "24-48 hrs", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "8556ec34-5fc9-46de-8be9-bce2fbd3ea06", "choice_type": "single"} {"question": "The segmental division of liver into eight segments is based on", "exp": "Right hepatic vein divides the right lobe into anterior (V VIII) and posterior segments ( VI-VII) Middle hepatic vein divides the liver into right and left lobes. This plane runs from the inferior vena cava to the gallbladder fossa. The Falciform ligament divides the left lobe into a medial- segment IV and a lateral pa - segment II and III. The poal vein divides the liver into upper and lower segments. The left and right poal veins branch superiorly and inferiorly to project into the center of each segment. ref - researchgate.net", "cop": 4, "opa": "Hepatic veins alone", "opb": "Poal vein alone", "opc": "Hepatic veins and common hepatic aery", "opd": "Hepatic veins and poal veins", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "457deca2-9136-4bbd-8b2e-e7ad123753f3", "choice_type": "single"} {"question": "Forelimb bud appears on", "exp": "(26 days) (135-IBS 7th) (125-1.B.Singh 8th)Timetable of some events* The forelimb bud appears about the 26th day (end of 4th week)* The hind limb bud appears about the 28th dayThe limbs become paddle shaped after about 4 days (5th week) and grooves between the future digits (digital rays) can be seen by the 36 the day (6th week). By the 50 th day or so (8th week) the elbows and knees are established and the fingers and toes are free. Rotation of limbs occurs during the 7th week. Cartilaginous models of bones start forming in the 6th week. And primary centres of ossification are seen in many bones in the 8th week. They are present in all long bones by the 12th week* The extremities are most susceptible to teratogens during the 4th to 7th week and slightly less susceptible in the 8th week", "cop": 2, "opa": "21 days", "opb": "26 days", "opc": "28 days", "opd": "30 days", "subject_name": "Anatomy", "topic_name": "Embryology", "id": "7917b88b-6bf8-4ed1-8cf7-d305a3301a2a", "choice_type": "single"} {"question": "Tongue is protrude by", "exp": "(Genioglossus) (252-BDC-3- 4th edition)Action of Extrinsic muscle of TongueGENIOGLOSSUSDraws the tongue forward and protrude the tip so that it points to the opposite side. The two muscle acting in union protrude the tongue in the midlineHYOGLOSSUSIt depresses the tongue** makes the dorsum convex and helps in retracting the protruded tongueSTYLOGLOSSUSDuring swallowing it pulls the tongue upwards and backwardsPALATOGLOSSUSPulls up root of the tongue and approximates the palatoglossal arches and thus closes oropharyngeal isthmus* Safety muscle of tongue is - Genioglossus* Ipsilateral deviation of tongue is due to unaltered action of - Genioglssus* Palsy of right genioglossus causes- devition of tongue to right**** All the intrinsic and extrinsic muscles EXCEPT THE PALATOGLOSSUS** are supplied by cranial part of accessory nerve through the pharyngeal plexusImportant Points1. Tip of the tongue drain into submental lymph nodes*2. Anterior 2/3 of the tongue drain into submandibular lymph node and posterior 1/3 of the tongue drain into Jugulo omohyoid (Lymph node of the tongue)3. Anterior 2/3 of tongue developed from first branchial arch*. Therefore it is supplied by lingual nerve** and chorda tympani4. Posterior 1/3 of tongue develops third branchial arch** therefore it is supplied by glossopharyngeal nerve**5. Posterior most part from the fourth arch: therefore supplied by the Vagus nerve6. Circumvallate papillae are innervated by Glossopharyngeal nerve**7. Circumvallate papillae- are situated on the mucous membrane just anterior to the sulcus terminalis an therefore their taste buds are innervated by ninth cranial nerve***8. Unilateral injury to hypoglossal nerve leads to(I) Hemiatrophy of involved side *(II) Deviation of tongue towards the same side *(III) Fasciculation of tongue *9. Intrinsic muscles of the tongue are derived from occipital somites", "cop": 3, "opa": "Hyoglossus", "opb": "Palatoglossus", "opc": "Genioglossus", "opd": "Styloglossus", "subject_name": "Anatomy", "topic_name": "Head & Neck", "id": "ac59984e-2555-450c-939e-f925c82e8516", "choice_type": "single"} {"question": "Trendelenburg sign is due to paralysis of", "exp": "TRENDELENBURG SIGN:- Normally,when the body weight is suppoed on one limb,the glutei of the suppoed side raise the opposite and unsuppoed side of the pelvis. However,if the abductor mechanism is defective,the unsuppoed side of the pelvis drops- Trendelenburg sign +ve. Sign is positive in defects of power- paralysis of the glutei medius and minimus ( supplied by superior gluteal nerve) ,defects of the fulcrum (congenital or pathological dislocation of hip),defects of weight. {Reference : BDC 6E pg no.70}", "cop": 2, "opa": "Gluteus maximus", "opb": "Gluteus medius", "opc": "Pyriformis", "opd": "Obturator externus", "subject_name": "Anatomy", "topic_name": "Lower limb", "id": "9016d9cf-33b8-422c-90f1-40a70fa071ed", "choice_type": "single"} {"question": "One unit of fresh blood raises Hb% ( Hemoglobin concentration ) by", "exp": "Single unit of whole blood raises Hb by 1 gm% and Hematocrit by 3% More than 70% of transfused cells will be ble after 24 hours Ref: Harrison's 19th edition Pgno :138", "cop": 3, "opa": "0.1gm%", "opb": "0.5 gm %", "opc": "1gm%", "opd": "2 gm%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "3dca8bb7-27e9-406f-b9ff-89d3b4c9d14f", "choice_type": "single"} {"question": "Implantation occurs at", "exp": "HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:72In humans implantation begins on the 6th day after feilization", "cop": 2, "opa": "2-3 days", "opb": "6-7 days", "opc": "15-20 days", "opd": "20-25 days", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "86484585-8118-4018-aae5-37f3021c3ef2", "choice_type": "single"} {"question": "The veins of the pericardium drain into", "exp": "The veins of pericardium drains into svc, pierced anteriorly . Ref - BDC 6th edition vol 1 pg 272", "cop": 1, "opa": "Superior vena cava", "opb": "Inferior vena cava", "opc": "Azygos vein", "opd": "Left brachiocephalic vein", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "cadc02cf-5a43-4b45-a7c5-c71f5ea92c8b", "choice_type": "single"} {"question": "Grade 1 Lymphedema means", "exp": ".", "cop": 4, "opa": "Pitting edema upto the ankle", "opb": "Pitting edema upto knee", "opc": "Non pitiing edema", "opd": "Edema disappearing after overnight rest", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "43b3d4d5-86a3-482b-8d78-1b1739fc8792", "choice_type": "single"} {"question": "The difference between hyosine and atropine is that hyosine", "exp": "Ref-KDT 6/e p109 Hyoscine is a CNS depression and can be caused as truth to serum (to induce twilight sleep). Atropine at low dose stimulates the brain whereas inhibiting it a very high concentration", "cop": 1, "opa": "Exes depression affect on the CNS it relative low doses", "opb": "Exes more potent effects on the hea than on the eye", "opc": "Is longer acting", "opd": "Hi sweetie kar anti motion sickness activity", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "f998149e-3c33-4a17-985a-2ad32d3b2342", "choice_type": "single"} {"question": "Strain used for Melanin is", "exp": "Ref histopathology p150 Other stains for Melanin are schmorl's method and enzyme histochemical method called DOPA oxidase", "cop": 3, "opa": "Oil red", "opb": "Gomori methamine silver strain", "opc": "Masson Fontana stain", "opd": "PAS stain", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "bfff599e-314b-4131-9c0f-15e2e6ca1a55", "choice_type": "single"} {"question": "Erb's point is formed by", "exp": "Erb's point is formed by the C5 and C6 root, anterior and posterior divisions of upper trunk, subscapular nerve and nerve to subclavius. Injury to upper trunk causes Erb's paralysis. B D Chaurasia 7th edition Page no: 59", "cop": 2, "opa": "C4 and C5", "opb": "C5 and C6", "opc": "C6 and C7", "opd": "C6 and T1", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "15378e47-a73a-4342-8e5e-eb3130022ae4", "choice_type": "single"} {"question": "Function of lumbricals area) Flexion at MCP jointb) Extension at IP jointsc) Adduction of the fingersd) Abduction of the fingers", "exp": "Lumbricals :\n\nFlexion - Metacarpophalangeal joints.\nExtension - Interphalangeal joints.", "cop": 4, "opa": "ac", "opb": "bc", "opc": "bd", "opd": "ab", "subject_name": "Anatomy", "topic_name": null, "id": "8c7f5af9-9dff-442f-abc9-e970d8a971cd", "choice_type": "single"} {"question": "Most common site of metastases in case of Osteosarcoma DELETE", "exp": "Almost 10 percnt of have metastases at presentation Metastases is most common to lungs, but Hematogenous spread to other organs is also possible -including lymph nodes, brain, skeleton Refer Apleys 9th/e p 207", "cop": 2, "opa": "Brain", "opb": "Lungs", "opc": "Liver", "opd": "Bladder", "subject_name": "Anatomy", "topic_name": null, "id": "1759ac94-08f6-47c9-aba0-1ed3909fde9c", "choice_type": "single"} {"question": "Obturator nerve arises from", "exp": "(Ventral rami of L2 L3 L4) (171, 320-BDC-2 4th)OBTURATOR NERVE - is a branch of lumbar plexus, it arises from ventral division of L2 L3 L4 segments of spinal cords.Branches of obturator nerve : Anterior divisionPosterior divisionMuscularPectineus, adductor longus, adductor brevis, gracilisObturator extemus, adductor magnus (adductor part)ArticularHip jointKnee jointVascular and cutaneousFemoral artery, Medial side of thighPopliteal arteryBranches of the lumbar plexus1. Iliohypogastric nerve (L1)2. Ilioinguinal nerve (L1)3. Genitofemoral nerve (L1, L2 ventral divisions)4. Obturator nerve (L2, L3 L4 ventral division)5. Lumbosacral trunk (L4, L5 ventral rami)6. Lateral cutaneous nerve of the thigh (L2 L3 dorsal division)7. Femoral nerve (L2, L3 L4 dorsal divisions)", "cop": 1, "opa": "Ventral division of L2 L3 L4", "opb": "Dorsal division of L2 L3 L4", "opc": "Ventral rami of L1 L2", "opd": "Dorsal rami of L1 L2", "subject_name": "Anatomy", "topic_name": "Lower Extremity", "id": "5c361810-9478-4b86-9e69-180ac6828fd5", "choice_type": "single"} {"question": "Klumpke's paralysis involved", "exp": "(C8, T1) (53-BDC-l 4th)ERB'S PARALYSISKLUMPKE'S PARALYSISSite of Injury - The region of the upper trunk of the brachial plexus is called Erb's point, six nerves meet here. Injury to the upper trunk causes Erb's paralysis.Lower trunk of brachial plexusCause of injury - Undue seperation of the head from the shoulder, which is commonly encountered in (i) birth injury (ii) fall on the shoulder (iii) during anaesthesiaUndue abduction of the arm, as in clutching something with the hands after a fall from a height or sometimes in birth injuryNerve root involved - Mainly C5 and partly C6Mainly T1 and partly C8Muscle paralysed - Mainly biceps, deltoid, brachialis, and brachioradialis. Partly supraspinatus, infraspinatus and supinatorDeformity - (position of the limb)Arm: Hangs by the side: It is adducted and medially rotated.Forearm: Extended and pronatedThe deformity is known as \"policeman's tip\" or \"porter *s tip hand'1. Intrinsic muscles of the hand (Tl)2. Ulnar flexors of the wrist and fingers (C8)Claw hand* due to the unopposed action of the longflexors and extensors of the fingers.(Hyperextension at the MCP joint and flexion at the IP joint)Disability: The following movements are lost1. Abduction and lateral rotation of the arm (shoulder)2. Flexion and supination of the forearm3. Biceps and supinator of the forearm4. Sensation are lost over a small area over the lower part of the deltoid1. Claw hand2. Cutaneous anaesthesia and analgesia in a narrow zone along the ulnar border of the forearm and hand3. Homer's syndrome (This is because of injury to sympathetic fibres to the head and neck that leave the spinal cord through nerve T14. Vasomotor changes5. Trophic changes", "cop": 4, "opa": "C5, 6", "opb": "C6, 7", "opc": "C7, 8", "opd": "C8, T1", "subject_name": "Anatomy", "topic_name": "Upper Extremity", "id": "bb2fa1e1-6a0e-454f-86b5-f91f7af4529c", "choice_type": "single"} {"question": "The toughest layer of the esophagus is the", "exp": "C i.e. Muscularis Muscularis externa is the toughest layer of esophagusQ; upper 1/3rd is composed of skeletal muscleQ, lower 1/3rd is composed of smooth muscleQ & the middle third is made up of both types of muscle.", "cop": 3, "opa": "Mucosa", "opb": "Submucosa", "opc": "Muscularis", "opd": "Adventitia", "subject_name": "Anatomy", "topic_name": null, "id": "d2ac1c1a-4c81-48fd-bb1d-3e5d37ef158e", "choice_type": "single"} {"question": "Median survival in carcinoma pancreas after surgery and adjuvant therapy", "exp": "After surgical resection and adjuvant therapy for pancreatic cancer, the Median survival is approximately 22 months, with 5 year survival of 15% to 20%. Most patients experience relapse of disease in the form of metastatic disease (85%) and less commonly, local recurrence (40%). In the absence of surgical resection, those with locally advanced disease who receive palliative chemotherapy may survive 10 to 12 months, whereas those with metastases rarely survive beyond 6 months Ref: Sabiston 20th edition Pgno :1547", "cop": 2, "opa": "12 months", "opb": "22 months", "opc": "32 months", "opd": "44 months", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "00291c70-3ed9-4a45-b647-0ecb0a5b5de9", "choice_type": "single"} {"question": "Common facial vein drains into", "exp": "Key concept:\nThe superficial temporal vein descends in front of the tragus, enters the parotid gland, and joins the maxillary vein to form the retromandibular vein. The anterior division of the retromandibular vein unites with the facial vein to form the common facial vein which drains into the internal jugular vein.", "cop": 1, "opa": "Internal jugular vein", "opb": "External jugular vein", "opc": "Subclavian vein", "opd": "Suboccipital veinous plexus", "subject_name": "Anatomy", "topic_name": null, "id": "e5141112-7cd4-405f-906d-96e8e8765f76", "choice_type": "single"} {"question": "Bronchopulmonary segments in right and left lungs are", "exp": "THE BRONCHOPULMONARY SEGMENTS - These are well-defined sectors of the lung, each one of which is aerated by a teiary or segmental bronchus. Each segment is pyramidal in shape with its apex directed towards the root of the lung. There are 10 segments on the right side and 10 on the left Ref : B D Chaurasia's Human Anatomy, seventh edition, volume 1 , pg. no. 251 ( table 16.3 )", "cop": 3, "opa": "9 and 11", "opb": "11 and 9", "opc": "10 and 10", "opd": "8 and 10", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "01815054-3edb-41be-a332-f85eeeb4fb8e", "choice_type": "single"} {"question": "Medullary carcinoma of thyroid is associated with mutation in", "exp": "Ref Robbins 8/e p1124_1126,9/e p284 Medullary thyroid cancer is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin. Medullary tumors are the third most common of all thyroid cancers and together make up about 3% of all thyroid cancer cases.[2 Approximately 25% of medullary thyroid cancer cases are genetic in nature, caused by a mutation in the RET proto-oncogene. This form is identified as familial medullary thyroid cancer (FMTC). When MTC occurs by itself it is termed sporadic medullary thyroid cancer (SMTC). When it coexists with tumors of the parathyroid gland and medullary component of the adrenal glands (pheochromocytoma) it is called multiple endocrine neoplasia type 2", "cop": 1, "opa": "RET", "opb": "RAS", "opc": "NF", "opd": "Rb", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "cb81a0ee-aa13-411f-b9fd-0b63b01abf4c", "choice_type": "single"} {"question": "The gold standard test for insulinoma", "exp": "\"The most reliable test to diagnose insulinoma is a fast up to 72 h with serum glucose, C-peptide, and insulin measurements every 4-8 h.\" --Harrison An insulinoma is an endocrine tumor of the pancreas derived from beta cells that ectopically secretes insulin, which results in hypoglycemia. The clinical symptoms are because of the effects of hypoglycaemia (sweating, tremor, palpitations, confusion, headache, disorientation, visual difficulties, irrational behaviour, or even coma) The diagnosis of insulinoma requires the demonstration of an elevated plasma insulin level at the time of hypoglycemia. This is because insulinomas do not reduce the secretion of insulin in the presence of hypoglycaemia. Whereas in a normal person, insulin levels would decrease with a decrease in blood glucose levels. The most reliable test to diagnose insulinoma is a fast up to 72 h with serum glucose, and insulin measurements every 4-8 h. The test is terminated if the patient becomes symptomatic or glucose levels are <40 mg/dL (2.2 mmol/L). Diagnosis of insulinoma is made if: A serum insulin level of 6 microunit/mL or more in the presence of blood glucose values below 40 mg/dL the ratio of plasma insulin to glucose is > 0.3 In addition to the above criteria, some other measurements are also required before making the diagnosis of insulinoma C-peptide level serum proinsulin level, serum sulfonylurea levels These additional tests are used because any hidden use of insulin or oral hypoglycemics taken by the patient would resemble insulinoma causing high levels of insulin in presence of hypoglycaemia. The combination of elevated proinsulin levels (normal in exogenous insulin/hypoglycemic agent users), elevated C-peptide levels (low in exogenous insulin users), antibodies to insulin (positive in exogenous insulin users), and measurement of sulfonylurea levels in serum or plasma will allow the correct diagnosis to be made. Ref : Harrison 17/e p2354", "cop": 1, "opa": "72 hr fasting test", "opb": "Plasma insulin levels", "opc": "C-peptide levels", "opd": "Low glucose levels < 30 mg/dl", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "dff49b7c-7586-44ba-88f1-107551e0e9c0", "choice_type": "single"} {"question": "Most common congenital anomaly of kidney", "exp": "Congenital anomalies of kidney and urinary tract is phenotypically variable and can affect the kidney(s) alone and/or the lower urinary tract. The spectrum includes more common anomalies such as vesicoureteral reflux and, rarely, more severe malformations such as bilateral renal agenesis. ref - researchgate.net", "cop": 3, "opa": "Ectopic kidney", "opb": "Renal duplication", "opc": "Horse shoe kidney", "opd": "Renal agenesis", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "37a36758-5001-4804-8b0f-89a8401f4059", "choice_type": "single"} {"question": "Antibody found in myositis", "exp": "Refer Harrison 17th/2038", "cop": 1, "opa": "Anti jo 1", "opb": "Anti scl 70", "opc": "Anti Sm", "opd": "Anti ku", "subject_name": "Anatomy", "topic_name": "Musculoskeletal system", "id": "1cbad5d6-430c-476a-bfb7-1ddef6540a04", "choice_type": "single"} {"question": "Kappa toxin released by clostridium perfringens is responsible for", "exp": "Exotoxins produces by C. Perfringens *Alpha toxin(lecithinase) - detroys RBC& WBC *phi toxin- myocardial depression *kappa toxin-destruction of connective tissue and blood vessels Ref:Bailey and love 27th edition Pg no :420", "cop": 4, "opa": "RBC destruction", "opb": "Myocardial depression", "opc": "Rhabdomyolysis", "opd": "Destruction of connective tissue and blood vessels", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "04363735-4e92-4722-be6b-628d1d11dac8", "choice_type": "single"} {"question": "Postprandial hyperglycemia may be controlled by", "exp": "(Refer: Rang and Dale's Clinical Pharmacology, 7th edition, pg no: 380-383)", "cop": 4, "opa": "Rosiglitazone", "opb": "Thiazide", "opc": "Pioglitazone", "opd": "Tolbutamide", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "c84f3442-108b-4a47-ac81-90585eebef55", "choice_type": "single"} {"question": "Klumpkey&;s paralysis affect", "exp": "KLUMPKEY'S PARALYSIS:- Lower plexus injury.Caused by undue abduction of the arm as in clutching something with hand after a fall from a height, or sometimes in bih injury. NERVE ROOTS INVOLVED: C8 and T1 nerve roots involved. MUSCLES PARALYSED: Intrinsic muscles of the hand{T1} Ulnar flexors of the wrist and fingers. DEFORMITY AND POSITION OF THE HAND: Claw hand due to the unopposed action of the long flexors and extensors of the fingers. In a claw hand, there is hyperextension at the metacarpophalangeal joints and flexion at the interphalangeal joints. DISABILITY: Biceps and supinator jerks are lost complete claw hand cutaneous anesthesia and analgesia in a narrow zone along the ulnar border of the forearm and hand. HORNER.S SYNDROME: If T1 is injured proximal to white ramus communicans to the first thoracic sympathetic ganglion, there is ptosis, miosis, anhydrosis, enophthalmos, and loss of ciliospinal reflex may be associated. this is because of injury to sympathetic fibers to the head and neck that leave the spinal cord through nerve T1. VASOMOTOR CHANGES: The skin area with sensory loss is warmer due to aeriolar dilatation. It is also drier due to the absence of sweating as there is loss of sympathetic activity. TROPHIC CHANGES: Longstanding cases of paralysis leads to dry and scaly skin. The nails crack easily with atrophy of the pulp of fingers.", "cop": 3, "opa": "C5 C6", "opb": "C6 C7", "opc": "C8 T1", "opd": "C4 C5", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "7ddfc56b-5677-4cfc-b110-1ff955eb26ea", "choice_type": "single"} {"question": "Potassium is absorbed in the jejunum by", "exp": "As with other substrates, the net movement of K+ across the intestinal mucosa is determined by the difference between two opposing unidirectional fluxes; compared to sodium fluxes, potassium fluxes are small. Net movement of K+ in jejunum and ileum occurs only down the electrochemical gradient (i.e., it is largely passive). Potassium diffuses primarily through the lateral spaces and tight junctions. In the colon potassium is usually secreted, and the luminal concentration must be above 25 mEq/L for net absorption to take place. This explains why potassium deficiency tends to develop in diarrhoea. Potassium secretion by the colon appears to be a passive process", "cop": 3, "opa": "Active transpo", "opb": "Facilitated transpo", "opc": "Passive transpo", "opd": "Active and passive transpo", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "5bf159c6-f623-4f55-8f30-1f5788bce630", "choice_type": "single"} {"question": "mood stabilzer used in the management of trigeminal neuralgia is", "exp": "Carbamazepine - USES - TRIGEMINAL NEURALGIA - TEMPORAL LOBE EPILEPSY - SECOND LINE MOOD STABILIZER Ref.Kaplon and Sadock, synopsis of psychitry, 11 th edition, pg no.935", "cop": 1, "opa": "carbamezepine", "opb": "valproate", "opc": "lamotrigine", "opd": "lithium", "subject_name": "Anatomy", "topic_name": "Pharmacotherapy in psychiatry", "id": "5d739a5a-3864-4e86-b99b-d1d9f687f1a1", "choice_type": "single"} {"question": "Compartment devoid of neurovascular bundle", "exp": "Posterior superficial compartment of leg is devoid of neurovascular bundle", "cop": 3, "opa": "Anterior compartment of leg", "opb": "Posterior deep compartment of leg", "opc": "Posterior superficial compartment of leg", "opd": "Lateral compartment of leg", "subject_name": "Anatomy", "topic_name": null, "id": "575f4d23-4fcc-46b1-8a31-1b4115297c3b", "choice_type": "single"} {"question": "Superficial incision on posterior triangle of neck lead to", "exp": "The posterior triangle or the side of the neck contains the accessory nerve, external jugular vein, the cervical plexus and proximal pas of the brachial plexus of nerves supplying the upper limb. Injury to the spinal accessory nerve not only results in debilitating trapezius dysfunction, but can also result in chronic pain and debilitation with prolonged shoulder girdle dysfunction.90 It usually presents after diagnostic lymph node biopsies of the posterior triangle of the neck, with an incidence of 3% to 8%. Ref - sciencedirect.com", "cop": 1, "opa": "Difficulty in shrugging of shoulder", "opb": "Difficulty in sta of abduction", "opc": "Difficulty in rotation of face towards the same side", "opd": "Difficulty in flexion", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "323848ae-d879-4740-87a0-9b9f2ab44237", "choice_type": "single"} {"question": "Left sided superior vena cava drains into", "exp": "Persistent left superior vena cava (PLSVC) is the most common variation of the thoracic venous system left sided svc drains into right atrium coronary sinus . Image ref - researchate.net", "cop": 3, "opa": "Right atrium", "opb": "Left atriurm", "opc": "Coronary sinus", "opd": "Pericardial space", "subject_name": "Anatomy", "topic_name": "Thorax", "id": "e3b7f4bd-3488-4eb2-9853-7da32814eaee", "choice_type": "single"} {"question": "Poo systemic shunt is not seen in", "exp": "B i.e. Spleen", "cop": 2, "opa": "Liver", "opb": "Spleen", "opc": "Anorectum", "opd": "Gastro Esophageal", "subject_name": "Anatomy", "topic_name": null, "id": "98f96e34-00a0-4240-ab4d-ab207d2a317c", "choice_type": "single"} {"question": "Intermediate filaments in muscle cells", "exp": "Intermediate filaments are used as tumor markers Epithelial cells:keratin Muscle cells:desnin Nucleus:lamin Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:8,9,14", "cop": 1, "opa": "Desnin", "opb": "Keratin", "opc": "Vimentin", "opd": "Lamin", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "5a82a485-b353-47d8-88d9-319a349cf616", "choice_type": "single"} {"question": "Sympathetic root of otic ganglion", "exp": "ROOTS OF OTIC GANGLION: Sensory root is by auriculotemporal nerve Sympathetic root is by sympathetic plexus around middle meningeal aery Secretomotor root is by lesser petrosal nerve from tympanic plexus formed by tympanic branch of cranial nerve IX Motor root is by a branch from nerve to medial pterygoid Ref BDC volume 3,sixth edition pg 311", "cop": 4, "opa": "Plexus around ICA", "opb": "Plexus around facial aery", "opc": "Plexus around ophthalmic aery", "opd": "Plexus around middle meningeal aery", "subject_name": "Anatomy", "topic_name": "Head and neck", "id": "20c1e739-4a22-43fd-b1ff-5017b02b1809", "choice_type": "single"} {"question": "Roots involved in Erb&;s palsy are", "exp": "Erb's point: one region of the upper trunk of the brachial plexuses is called Erb's point. Six nerves meet here. Injury to the upper trunk causes Erb's paralysis. CAUSES: undue separation of the head from the shoulder, which is common in -Bih injury Fall on the shoulder During anaesthesia Nerve roots involved C5, C6, Suprascapular nerve, nerve to subclavius, anterior division, posterior division. DEFORMITY AND POSITION OF THE LIMB: ARM: Hangs by the side, it is adducted and medially rotated. FOREARM: Extended and pronated. DISABILITY: The following movements are lost Abduction and lateral rotation of the arm at the shoulder joint. flexion and supination of the forearm. Biceps and supinator jerks are lost. sensations are lost over a small area over the lower pa of the deltoid. REF: BD Chaurasia 7th edition Page no: 59 Figure: 4.15, page no: 59 - BD Chaurasia- upper limb & thorax, 7 the edition", "cop": 2, "opa": "Posterior primary rami of C6- C7", "opb": "Anterior primary rani of C5-C6", "opc": "Posterior primary rami of C8-T1", "opd": "Posterior primary rami of C7-C8", "subject_name": "Anatomy", "topic_name": "Upper limb", "id": "4f86c318-9319-4a5e-bf67-b45140310fde", "choice_type": "single"} {"question": "deja vu means", "exp": "deja vu=== feeling of familiarity to a novel stimulus jamais vu==feeling of unfamiliarity to a familiar stimulus ref. Kaplon and sadock, synopsis of psychiatry, 11th edition, pg no.194", "cop": 3, "opa": "Illusion that what one is hearing, one has heard previously", "opb": "A unfamiliar thought regarded as repetition of a previous thought", "opc": "Unfamiliar situations or events feel strangely familiar", "opd": "Feeling of strangeness to familiar situation", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "2df8cc22-36d7-4bce-8afc-0faaa49a7f51", "choice_type": "single"} {"question": "Majority of the afferent blood supply to liver is from", "exp": "Ans d): Portal veinThe liver is the largest gland in the body Its three basic functions are:* bile production & secretion* metabolism of fat, carbohydrate & protein* Blood filtration (removal of bacteria & foreign particles gained en trance from intestine)It has dual supplyHepatic artery - oxygenated blood - 30%Portal vein - venous blood rich in products of digestion -70%.", "cop": 4, "opa": "Hepatic vein", "opb": "Hepatic artery", "opc": "IVC", "opd": "Portal vein", "subject_name": "Anatomy", "topic_name": "Blood Vessels of Abdomen and Pelvis", "id": "13c06b24-944b-463b-9008-d073b43b5779", "choice_type": "single"} {"question": "Hematuria with dysmorphia RBC 's are seen in", "exp": "Ref Robbins 9/e p898 The onset of the kidney disease tends to be abrupt, her- alded by malaise, a slight fever, nausea, and the nephritic syndrome. In the usual case, oliguria, azotemia, and hyper- tension are only mild to moderate. Characteristically, there is gross hematuria, the urine appearing smoky brown rather than bright red. Some degree of proteinuria is a constant feature of the disease, and as mentioned earlier it occasionally may be severe enough to produce the nephrotic syndrome. Serum complement levels are low during the active phase of the disease, and serum anti-streptolysin O antibody titers are elevated in poststreptococcal cases. Dysmorphia of RBC is also seen", "cop": 1, "opa": "Acute glomerulonephritis", "opb": "Renal TB", "opc": "Renal calculi", "opd": "Chronic renal failure", "subject_name": "Anatomy", "topic_name": "Haematology", "id": "d60ab3d6-1d76-4f43-82b8-3f9447fd2a14", "choice_type": "single"} {"question": "Middle path regimen is used in the treatment of", "exp": "Middle path regimen is used in the treatment of SPINAL TB. 1)Drugs (ATT) 2)Surgery: INDICATIONS: 1)Defaulter 2)Relapses 3)Resistance 4)Compression over vital structure. Surgery done is amterolateral decompression with coical rib/fibular stut grafting.", "cop": 1, "opa": "TB Spine", "opb": "TB Hip", "opc": "TB Knee", "opd": "TB Meningitis", "subject_name": "Anatomy", "topic_name": "Skeletal infections", "id": "89052513-1948-4f0d-b3b0-97150854c7b6", "choice_type": "single"} {"question": "Cremasteric aery is a branch of", "exp": "The inferior epigastric aery - It arises from the external iliac aery near its lower end just above the inguinal ligament. It runs upwards and medially in the extraperitoneal connective tissue, passes just medial to the deep inguinal ring, pierces the fascial transversalis at the lateral border of the rectus abdominis and enters the rectus sheath by passing in front of the arcuate line .Within the sheath it supplies the rectus muscle and ends by anastomosing with the superior epigastric aery. branches of inferior epigastric aery - (a) A cremasteric branch - To the spermatic cord, or the aery of the round ligament in females; (b) A pubic branch - Which anastomoses with the pubic branch of the obturator aery; (c) muscuiarbranches - To the rectus abdominis , and (d) cutaneous branches - To the overlying skin. Ref : B D Chaurasia's Human Anatomy , seventh edition, volume 2 , pg. no. 229", "cop": 3, "opa": "Internal pudendal aery", "opb": "External pudendal aery", "opc": "Inferior epigastric aery", "opd": "Superior epigastric aery", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "8cdfca67-fbb0-409c-9b37-eb6b10bdb3a6", "choice_type": "single"} {"question": "Cells are most radiosensitive in", "exp": "Ref Robbins9/e p140 Cells are most radiosensitive in G2M interphase Cells are least radioactive in Sphase", "cop": 2, "opa": "S phase", "opb": "Mphase", "opc": "G1 phase", "opd": "G0 phase", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "e7088255-c920-4a23-a237-36fb114323d1", "choice_type": "single"} {"question": "Mitral stenosis is associated with", "exp": "Ref Harrison 19 th ed pg 1540 MS and sinus rhythm, the P wave usually suggests LA enlargement ). It may become tall and peaked in lead II and upright in lead V1 when severe pulmonary hypeension or TS complicates MS and right atrial (RA) enlargement occurs. The QRS complex is usually normal", "cop": 1, "opa": "Right ventricular hyperophy", "opb": "Left ventricular hyperophy", "opc": "Left axis detion", "opd": "QRS complex", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "000e0b20-8273-4c56-a8f9-029a10f48934", "choice_type": "single"} {"question": "Maintenence level of Mixed venous oxygen saturation in shock must be", "exp": "Mixed venous oxygen saturation The percentage saturation of oxygen returning to the hea from the body is a measure of the oxygen delivery and extraction by the tissues. Accurate measurements is analysis of blood drawn from a long central line placed in the right atrium Normal mixed venous oxygen saturation levels are 50-70%. Levels below 50% indicate inadequate oxygen delivery and increased oxygen extraction by the cells. This is consistent with hypovolemic or cardiogenic shock. Ref: Bailey and love 27th edition Pgno: 17", "cop": 2, "opa": ">70%", "opb": "50-70%", "opc": "40-50%", "opd": "<40%", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "37d6abde-273f-477b-a401-dbc29f12e67c", "choice_type": "single"} {"question": "Pudendal nerve supplying motor pa to external sphincter is derived from", "exp": "The striated sphincter is innervated by the pudendal nerve from the S2 - S3 nerve roots. The neurons that innervate the urethral sphincter originate in the cord, in an area termed Onuf&;s nucleus. The autonomic nervous system also controls the IUS muscle because it is made of smooth muscle fibers.", "cop": 4, "opa": "L5 - S1 roots", "opb": "S1 - S2 roots", "opc": "L2 - L3 roots", "opd": "S2 - S3 roots", "subject_name": "Anatomy", "topic_name": "Abdomen and pelvis", "id": "2ad6d4f5-1cd2-42dd-b540-e051727405b3", "choice_type": "single"} {"question": "\"Raindrop skull\" is seen in", "exp": ".", "cop": 3, "opa": "Hemophilia", "opb": "Thalassemia", "opc": "Multiple Myeloma", "opd": "Hodgkin's lymphoma", "subject_name": "Anatomy", "topic_name": "All India exam", "id": "cfc18d88-ef4c-4f77-9321-007d5375ef17", "choice_type": "single"} {"question": "Sirolimus is more likely than cyclosporine to cause", "exp": "Clyclosporine and tacrolimus cause nephrotoxicity as an adverse effect. Sirolimus results in bone marrow suppression and thus may cause anemia ,thrombocytopenia and leukopenia", "cop": 4, "opa": "Hypeension", "opb": "Osteoporosis", "opc": "Renal insufficiency", "opd": "Thrombocytopenia", "subject_name": "Anatomy", "topic_name": "Other topics and Adverse effects", "id": "a49103c7-ade1-4a4f-989a-f6da178b3cc5", "choice_type": "single"} {"question": "CECT with nodular enhancement is suggestive of", "exp": "Most common benign tumor of the liver Mainly seen in women of 45 years Small capillary hemangiomas(no clinical significance), larger cavernous hemangioma Usually single and <5 cm in diameter, occur equally in right and left liver Giant hemangioma: lesion>5cm Pathology Microscopically: Endothelium-lines, blood filled spaces that are seperated by thin, fibrous septa Enlargement of hemangiomas are by ectasia rather than neoplasia Clinical features Most commonly asymptomatic and incidentally found on imaging studies Large compressive masses may cause vague upper abdominal symptoms Kasabach-Merritt syndrome; syndrome of thrombocytopenia and consumptive coagulapathy Rarely seen LFT's and tumor markers are normal Diagnosis Diagnosis is made radiologically CT and MRI are diagnostic if a typical peripheral nodular enhancement pattern is seen Percutaneous biopsy is potentially dangerous and inaccurate not recommended Treatment Observation for asymptomatic cases Enucleation with inflow control is TOC for symptomatic cases Ref:Sabiston 20th edition Pgno :1456-1457", "cop": 3, "opa": "Hepatic adenoma", "opb": "FNH", "opc": "Hemangioma", "opd": "Cholangiodenoma", "subject_name": "Anatomy", "topic_name": "G.I.T", "id": "d60172b9-0796-4cc9-98b0-25c9f1b4e287", "choice_type": "single"} {"question": "Splanchnic nerves are", "exp": "Splanchnic nerves are preganglionic Sympathetic nerves", "cop": 1, "opa": "Preganglionic Sympathetic nerves", "opb": "Postganglionic Sympathetic nerves", "opc": "Preganglionic parasympathetic nerves", "opd": "Postganglionic parasympathetic nerves", "subject_name": "Anatomy", "topic_name": null, "id": "23649941-a638-4a5c-89e3-e6bab80490c9", "choice_type": "single"} {"question": "Oil red o staining used for", "exp": "Ref Bancroft histology 7/e p 83 Air dry frozen sections on slides for 30 minutes minimum 2. Fix in 10% neutral buffered formalin for 10 minutes 3. Dip in 60% isopropanol 1 time quickly 4. Stain in working Oil Red O solution for 15 minutes 5.", "cop": 1, "opa": "Frozen section", "opb": "Glutaraldehyde fixed specimen", "opc": "Alcohol fixed specimen", "opd": "Formalin fixed specimen", "subject_name": "Anatomy", "topic_name": "General anatomy", "id": "72ea6792-14ae-4659-9bf9-18afd2edeea7", "choice_type": "single"}