Question: How many times did plague occur in the place where Vanity's creator died?

Context paragraphs:
paragraph_text: By contrast, Tom Wolfe's Bonfire of the Vanities (1987) portrays a wealthy, white protagonist, Sherman McCoy, getting lost off the Major Deegan Expressway in the South Bronx and having an altercation with locals. A substantial piece of the last part of the book is set in the resulting riotous trial at the Bronx County Courthouse. However, times change, and in 2007, the New York Times reported that "the Bronx neighborhoods near the site of Sherman's accident are now dotted with townhouses and apartments." In the same article, the Reverend Al Sharpton (whose fictional analogue in the novel is "Reverend Bacon") asserts that "twenty years later, the cynicism of The Bonfire of the Vanities is as out of style as Tom Wolfe's wardrobe."
title: The Bronx
paragraph_text: The Martyrdom of Saint Lawrence is a 1558 painting by Titian, now in the church of I Gesuiti in Venice. It so impressed Philip II of Spain that he commissioned a second version in 1567 for the basilica at El Escorial.
title: The Martyrdom of Saint Lawrence (Titian)
paragraph_text: The plague theory was first significantly challenged by the work of British bacteriologist J. F. D. Shrewsbury in 1970, who noted that the reported rates of mortality in rural areas during the 14th-century pandemic were inconsistent with the modern bubonic plague, leading him to conclude that contemporary accounts were exaggerations. In 1984 zoologist Graham Twigg produced the first major work to challenge the bubonic plague theory directly, and his doubts about the identity of the Black Death have been taken up by a number of authors, including Samuel K. Cohn, Jr. (2002), David Herlihy (1997), and Susan Scott and Christopher Duncan (2001).
title: Black Death
paragraph_text: Vanity is an oil painting by Italian late Renaissance painter Titian, dated to around 1515 and now held at the Alte Pinakothek in Munich, Germany.
title: Vanity (Titian)
paragraph_text: "Ms. Vanity" is the debut single by former Australian Idol contestant Rob Mills. "Ms. Vanity" was released as the lead single from Rob's debut album "Up All Night", and reached a peak position of #6 on the Australian ARIA Singles Chart. It is to date Rob's first and only top ten single. "Ms. Vanity" lasted a relatively short 8 weeks on the chart.
title: Ms. Vanity
paragraph_text: The Black Death ravaged much of the Islamic world. Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. Plague repeatedly struck the cities of North Africa. Algiers lost 30 to 50 thousand inhabitants to it in 1620–21, and again in 1654–57, 1665, 1691, and 1740–42. Plague remained a major event in Ottoman society until the second quarter of the 19th century. Between 1701 and 1750, thirty-seven larger and smaller epidemics were recorded in Constantinople, and an additional thirty-one between 1751 and 1800. Baghdad has suffered severely from visitations of the plague, and sometimes two-thirds of its population has been wiped out.
title: Black Death
paragraph_text: The 2013 Houphouët-Boigny stampede occurred as crowds departed a New Year's Eve fireworks display in the early hours of 1 January 2013 near the Félix Houphouët-Boigny Stadium in Abidjan, Ivory Coast. It resulted in 61 deaths and over 200 injuries, mostly women and children. This was the second time in four years that a fatal stampede occurred at the stadium.
title: 2013 Houphouët-Boigny stampede
paragraph_text: Acral necrosis is a symptom common in bubonic plague. The striking black discoloration of skin and tissue, primarily on the extremities (``acral ''), is commonly thought to have given rise to the name`` Black Death,'' associated both with the disease and the pandemic which occurred in the 14th century. The term in fact came from the figural sense of ``black '', that is ghastly, lugubrious or dreadful.
title: Acral necrosis
paragraph_text: The historian Francis Aidan Gasquet wrote about the 'Great Pestilence' in 1893 and suggested that "it would appear to be some form of the ordinary Eastern or bubonic plague". He was able to adopt the epidemiology of the bubonic plague for the Black Death for the second edition in 1908, implicating rats and fleas in the process, and his interpretation was widely accepted for other ancient and medieval epidemics, such as the Justinian plague that was prevalent in the Eastern Roman Empire from 541 to 700 CE.
title: Black Death
paragraph_text: The Late Middle Ages spanned the 14th and early 15th centuries. Around 1300, centuries of European prosperity and growth came to a halt. A series of famines and plagues, such as the Great Famine of 1315–1317 and the Black Death, killed people in a matter of days, reducing the population of some areas by half as many survivors fled. Kishlansky reports:
title: History of Europe
paragraph_text: Hate 2 O ("H2Odio" in Italy) is a 2006 film written, directed, and produced by Alex Infascelli. It is the followup to his 2004 film "The Vanity Serum", considered by many to be his breakout film. It was released in Italy on May 5, 2006.
title: Hate 2 O
paragraph_text: The Black Death, also known as the Great Plague, the Black Plague, or simply the Plague, was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia and peaking in Europe from 1347 to 1351. The bacterium Yersinia pestis, which results in several forms of plague, is believed to have been the cause. The plague created a series of religious, social and economic upheavals, which had profound effects on the course of European history.
title: Black Death
paragraph_text: Informal learning is one of three forms of learning defined by the Organisation for Economic Co-operation and Development (OECD). Informal learning occurs in a variety of places, such as at home, work, and through daily interactions and shared relationships among members of society. For many learners this includes language acquisition, cultural norms and manners. Informal learning for young people is an ongoing process that also occurs in a variety of places, such as out of school time, in youth programs at community centers and media labs.
title: Education
paragraph_text: In 1466, perhaps 40,000 people died of the plague in Paris. During the 16th and 17th centuries, the plague was present in Paris around 30 per cent of the time. The Black Death ravaged Europe for three years before it continued on into Russia, where the disease was present somewhere in the country 25 times between 1350 to 1490. Plague epidemics ravaged London in 1563, 1593, 1603, 1625, 1636, and 1665, reducing its population by 10 to 30% during those years. Over 10% of Amsterdam's population died in 1623–25, and again in 1635–36, 1655, and 1664. Plague occurred in Venice 22 times between 1361 and 1528. The plague of 1576–77 killed 50,000 in Venice, almost a third of the population. Late outbreaks in central Europe included the Italian Plague of 1629–1631, which is associated with troop movements during the Thirty Years' War, and the Great Plague of Vienna in 1679. Over 60% of Norway's population died in 1348–50. The last plague outbreak ravaged Oslo in 1654.
title: Black Death
paragraph_text: The Black Death is thought to have originated in the arid plains of Central Asia, where it then travelled along the Silk Road, reaching Crimea by 1343. From there, it was most likely carried by Oriental rat fleas living on the black rats that were regular passengers on merchant ships. Spreading throughout the Mediterranean and Europe, the Black Death is estimated to have killed 30–60% of Europe's total population. In total, the plague reduced the world population from an estimated 450 million down to 350–375 million in the 14th century. The world population as a whole did not recover to pre-plague levels until the 17th century. The plague recurred occasionally in Europe until the 19th century.
title: Black Death
paragraph_text: It is recognised that an epidemiological account of the plague is as important as an identification of symptoms, but researchers are hampered by the lack of reliable statistics from this period. Most work has been done on the spread of the plague in England, and even estimates of overall population at the start vary by over 100% as no census was undertaken between the time of publication of the Domesday Book and the year 1377. Estimates of plague victims are usually extrapolated from figures from the clergy.
title: Black Death
paragraph_text: In addition to arguing that the rat population was insufficient to account for a bubonic plague pandemic, sceptics of the bubonic plague theory point out that the symptoms of the Black Death are not unique (and arguably in some accounts may differ from bubonic plague); that transference via fleas in goods was likely to be of marginal significance; and that the DNA results may be flawed and might not have been repeated elsewhere, despite extensive samples from other mass graves. Other arguments include the lack of accounts of the death of rats before outbreaks of plague between the 14th and 17th centuries; temperatures that are too cold in northern Europe for the survival of fleas; that, despite primitive transport systems, the spread of the Black Death was much faster than that of modern bubonic plague; that mortality rates of the Black Death appear to be very high; that, while modern bubonic plague is largely endemic as a rural disease, the Black Death indiscriminately struck urban and rural areas; and that the pattern of the Black Death, with major outbreaks in the same areas separated by 5 to 15 years, differs from modern bubonic plague—which often becomes endemic for decades with annual flare-ups.
title: Black Death
paragraph_text: Christian Ackermann was born in Königsberg. He worked in Riga, Stockholm, and Gdańsk, before becoming active in Tallinn from about 1672 until his death in 1710. In 1675, Ackermann moved to Tallinn and acquired his own workshop. He probably died either in 1710 or a short time later from plague.
title: Christian Ackermann
paragraph_text: The Late Middle Ages was marked by difficulties and calamities including famine, plague, and war, which significantly diminished the population of Europe; between 1347 and 1350, the Black Death killed about a third of Europeans. Controversy, heresy, and schism within the Church paralleled the interstate conflict, civil strife, and peasant revolts that occurred in the kingdoms. Cultural and technological developments transformed European society, concluding the Late Middle Ages and beginning the early modern period.
title: Middle Ages
paragraph_text: The Black Death, also known as the Great Plague, the Black Plague, or simply the Plague, was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia and peaking in Europe from 1347 to 1351. The bacterium Yersinia pestis, which results in several forms of plague, is believed to have been the cause. The plague created a series of religious, social and economic upheavals, which had profound effects on the course of European history.
title: Black Death

Reasoning steps:
Vanity >> creator >>>> Titian
Titian >> place of death >>>> Venice
How many times did plague occur in Venice ? >>>> 22

Answer: spans: 22