Aarushhh/wikipedia-simple-splitted huggingface dataset:
Viruses are the ultimate expression of parasitism. They not only take nutrition from the host cell but also direct it metabolic machinery to synthesize new virus particles. viral chemotherapy was considered impossible, as it would require interference with cellular metabolism in the host.

Classification
1. Anti-Herpes virus : idoxurudine, trifluridine, Acyclovir, valacyclovir, Famciclovir, Ganciclovir, Valganciclovir, Cidofovir, Foscarnet, Fomivirsen

2. Anti-Influenza virus: Amantadine, rimantadine, Oseltamivir, Zanamivir

3. Anti-Hepatitis virus/nonselective antiviral drugs Primarily for hepatitis B: Lamivudine, Adefovir dipivoxil, Tenofovir Primarily for hepatitis C: Ribavirin, Interferon α

4. Anti retrovirus:

(A) neucleoside rivers transcriptas inhibitor: Zidovudine

Didanosine, Stavudine, lamivudine, Abacavir, Emtricitabine, Tenofovir

(B) nonnucleoside reverse transcriptase inhibitors (NNRTIs): Nevirapine, Efavirenz, Delavirdine
(C) Protease inhibitors: Ritonavir, Atazanavir, Indinavir, Nelfinavir, Saquinavir, Amprenavir

(D) Entry (Fusion) inhibitor: Enfuvirtide

(E) CCR5 receptor inhibitor: Maraviroc

(F) Integrase inhibitor: Raltegravir

Acyclovir 
This deoxiguanosine analogue antiviral drug requires a virus specific enzyme for conversion to the active metabolite that inhibits DNA synthesis and viral replication.

Acyclovir is  taken by the virus infected cells. Because of selective generation of the active inhibitor in the virus infected cell and its greater inhibitory effect on viral DNA synthesis, acyclovir has low toxicity for host cells: a several hundred-fold chemotherapeutic index has been noted.
Pharmacokinetics 
Only about 20% of an oral dose of acyclovir is absorbed. It is little plasma protein bound and is widely distributed attaining CSF concentration that is 50% of plasma concentration. After topical application, it penetrates cornea well. Acyclovir is primarily excreted unchanged in urine, both by glomerular filtration and tubular secretion; plasma t½ is 2–3 hours.

Use 

 Acyclovir is very usefull in patients with normal as well as deficient immune status.

 genital Herpes simplex generally caused by type 2 virus can be treated by topical, oral or parenteral acyclovir depending on stage & severity of disease.
Primary disease: Topical treatment has low efficacy; 5% ointment is applied locally 6 times a day for 10 days. This is useful if started early and in mild cases. Late and more severe cases should receive oral therapy (1 g/day in 5 divided doses or 400 mg TDS for 10 days) in addition to local therapy. Both local and oral therapies afford symptomatic relief and rapid healing of lesions, but do not prevent recurrences

 Mucocutaneous H. simplex It is a type-1 virus disease, remains localized to lips and gums; does not usually require specific treatment, but acyclovir skin cream may provide some relief. Spreading lesions may be treated with 10 day oral acyclovir. The disease often gets disseminated in immunocompromised individuals and may be treated with oral or i.v. acyclovir (15 mg/kg/day) for 7 days, but recurrences are not prevented.
H. simplex encephalitis (type-1 virus): Acyclovir 10 to 20 mg/kg/8 hr i.v. for >10 day is the drug of choice. Treatment is effective only if started early: delay precludes salutary effect on mortality and neurological complications.

Side effects 

 topical: Stinging & burning sensation after each application.
 oral: The drug is used  for headache, nausea, malaise and some CNS effects.
 Intravenous: Rashes, sweating, emesis and fall in BP occur only in few patients. Dose-dependent decrease in g.f.r. is the most important toxicity; occurs especially in those with kidney disease; normalises on discontinuation of the drug
Amantadine 
Chemically, it is a unique tricyclic amine unrelated to any nucleic acid precursor, but inhibits replication of influenza A virus. the activity of amantadine is strain specific, influenza b is not affected. H5N1 and H1N1 strains of Influenza A are resistant in most areas. it appears to act an early step (possibly uncoating) as well as at a late step (viral assembly) in viral replication. protein designated M2 which acts as an Ion channel has been identify as one of is targets of action. Resistance to amantadine develops by mutation causing amino acid substitutions in the M2 protein.

Uses 

 Prophylaxis of influenza A2 during an epidemic or seasonal influenza, especially in high risk patients. Influenza season and epidemics generally last ~ 2 months, and only this period needs to be covered by prophylaxis.

 when the Epidemic causing strain of virus is known to be sensitive to amantadine, should prophylactic use be considered.
However, amantadine is no longer recommended in united kingdom, either for prophylaxis or for treatment of influenza.

 Treatment of influenzal (A2) illness: a modest therapeutic effect (reduction in fever, congestion, cough and quicker recovery) occurs if the drug is given immediately after the symptoms appear. A 5 day treatment is advised.

Adverse effects 
Nausea, Anorexia, Insomnia, Dizziness, Nightmares, Lack of mental concentration, Rarely Hallucinations have been reported. Ankle edema occurs due to local vasoconstriction.

Interferon α 
α Interferons (IFNs)are low molecular weight glycoprotein cytokines produced by host cells in response to viral infections, TNFα, IL-1 and some other inducers.
They have nonspecific antiviral activity as well as other complex effects on immunity and cell proliferation. interferons binds to a very specific cell surface receptors and affect its replication at multiple steps,  viral penetration, synthesis of viral mRNA, assembly of viral particles and their release, but the most widespread effect is direct or indirect suppression of viral protein synthesis, i.e. inhibition of translation. interfeorn receptor like JAK STAT tyrosine protein kinase receptors which on activation phosphorylate cellular proteins. These then migrate to the nucleus and induce transcription of ‘interferon-inducedproteins’ which exert antiviral effects

Uses
Uses 

 Chronic hepatitis B: IFNα2Α 2.5−5 ΜU/m2 or IFNα2Β 5−10 ΜU given 3 times per week for 4–6 months causes disappearance of HBVDNA from plasma and improvement in liver function tests/histology in nearly half of the patients. High doses (10 MU) injected thrice weekly for 6 months often produce prolonged remission, but relapses do occur. The pegIFNs 180 μg s.c. weekly for 24 to 48 weeks produce better and more sustained responses.

 Chronic hepatitis C: IFNα2Β 3ΜU 3 times weekly for 6–12 months has produced remission in 50–70% patients. Viral RNA becomes undetectable and liver function tests return to normal. Histology improves if response is sustained. However, relapses occur in majority of patients. PegIFNs 180 μg/week are more effective and induce longer lasting remissions. Combination therapy with IFN/pegIFN + ribavirin is particularly indicated in patients who do not respond to IFN alone.
AIDS-related Kaposi’s sarcoma: IFN is used to treat AIDS related Kaposi’s sarcoma, but not to treat HIV as such. However, interferon accentuates haematological toxicity of zidovudine.

 Condyloma acuminata: caused by papilloma virus is usually treated with topical podophyllin. Intralesional interferon injection may be used in refractory cases.

Adverse effects 

 Flu-like symptoms—fatigue, aches and pains, malaise, fever, dizziness, anorexia, nausea, taste and visual disturbances develop few hours after each injection, but become milder later.

 neurotoxicity - numbness, neuropathy, altered behaviour, mental depression, tremor, sleepiness, very rarely convulsions

Antiviral drugs are a type of drug used for treating viral infection. Most antivirals are used for specific viral infections, while a broad-spectrum antiviral works against a wide range of viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen (something that causes disease); instead they stop their development.
Antiviral drugs are a type of antimicrobials, a larger group which also includes antibiotic (also called antibacterial), antifungal and antiparasitic drugs, or antiviral drugs based on monoclonal antibodies. Most antivirals do not cause much damage to the body, and can be used to treat infections. They are different from viricides, which are not medicine but deactivate or destroy virus particles inside or outside the body. Natural antivirals are made by some plants such as eucalyptus and Australian tea trees.

References 
all drugs mechanism of action by uvmedicine.store

Related pages
Antibiotics
Drugs
Viktor Josef Dammertz (8 June 1929 – 2 March 2020) was a German bishop of the Roman Catholic Church. He was born in Schaephuysen, Rheurdt. He became a priest in 1957. He served as bishop of Augsburg from 1993 until his retirement in 2004.

Dammertz died on 2 March 2020 in Eresing, at the age of 90.

References

1929 births
2020 deaths
German Roman Catholic bishops
A viral infection (or viral disease, or infectious disease) occurs when a living thing's body is entered in an unwanted way by disease-causing viruses, and able to be caught from others virus particles (virions) attach to and enter susceptible cells.

Structural characteristics 
Basic structural features, such as genome type, virion shape and replication site, generally share the same features among virus species inside the same family.

References 

Virology
Infectious diseases
Animaniacs is an American animated series made Wellesley Wild and Steven Spielberg. It first started showing on Hulu in 2020. It is a revival of the 1993 television show Animaniacs.

Voice Cast
Rob Paulsen - Yakko, Pinky, Dr. Scratchisniff
Tress MacNeille - Dot
Jess Harnell - Wakko
Natalie Palamides, Vanessa Marshall - Slappy
Stephanie Escajeda - Nora Rita Norita
Asher Bishop - Skippy
Kel Mitchell - Newt
Maurice LaMarche - Brain
William Salyers -  Pesto
Trey Parker - Buttons
Frank Welker - Runt
John Mariano - Bobby
Christy Carlson Romano - Minerva
Chloë Grace Moretz - Katie Kaboom

Episodes

References

Notes

2020s American animated television series
2020s American comedy television series
2020s American children's television series
English-language television programs

Hulu original series
Soundaraj Periyanayagam (6 June 1949 – 21 March 2020) was an Indian bishop of the Roman Catholic Church. He was born in Periya Kozhappalur. He became a priest in 1983. He served as bishop of Vellore from 2006 until his death in 2020.

Periyanayagam died on 21 March 2020 in Chetpet, Tamil Nadu, at the age of 69.

References

1949 births
2020 deaths
Indian Roman Catholic bishops
The main types of antimicrobial agents are disinfectants (such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which kill microorganisms within the body). The term "antibiotic" originally described only those creations that came from living microorganisms but is now also applied to synthetic agents, such as sulfonamides or fluoroquinolones. The term also used to be only applied to antibacterials, but its meaning has widened to include all antimicrobials. Antibacterial agents can be further grouped into bactericidal agents, which kill bacteria, and bacteriostatic agents, which slow down or stall bacterial growth. In response, further advancements in antimicrobial technologies have resulted in solutions that can go past simply stopping germ growth. Instead, certain types of porous media have been made to kill microbes on contact.

References
References 

Microbiology
Pharmacotherapy is therapy using medication, as separate from therapy using surgery (surgical therapy), radiation (radiation therapy), movement (physical therapy), or other methods. Among physicians, sometimes the term medical therapy refers specifically to pharmacotherapy as separate to surgical or other therapy; for example, in oncology, medical oncology is differentiated from surgical oncology. Pharmacists are experts in pharmacotherapy and are responsible for ensuring the safe, appropriate, and economical use of pharmaceutical drugs. The skills required to function as a pharmacist require knowledge, training and experience in biomedical, pharmaceutical and clinical sciences.  Pharmacology is the science that aims to continually improve pharmacotherapy. The pharmaceutical industry and academia use basic science, applied science, and translational science to create new pharmaceutical drugs.

Related pages 
Chemotherapy

References 

Pharmacology
Inna Vladimirovna Makarova (; 28 July 1926 – 25 March 2020) was a Russian actress. She is best known for her role as Lyubov Shevtsova in  The Young Guard (1948). Her other movie credits include It Happened in the Donbass (1945), The Return of Vasili Bortnikov (1953),The Rumyantsev Case (1956), The Height (1957), Balzaminov's Marriage (1964), Russian field (1971), It Is Not Evening Yet (1973) and Dead Souls (1984). In 1985, she was made a People's Artist of the USSR.

Makarova was born in Tayga and grew up in Novosibirsk. She was married to Sergei Bondarchuk. Her daughter was actress Natalya Bondarchuk. She died in Moscow on 25 March 2020 at the age of 93.

References

Other websites

1928 births
2020 deaths
Disease-related deaths in Moscow
Russian movie actors
Russian television actors
Soviet movie actors
Soviet television actors
Farzaneh Taidi (‎; 1945 – 25 March 2020) was an Iranian actress. She was born in Tehran. She appeared in a number of Persian language movies starting in the 1970s. Her movie credits include Hell + Me, The Eighth Day of the Week and The Journey of the Stone. She also appeared in Not Without My Daughter (1991).

On 25 March 2020, Taidi died in London, United Kingdom of cancer. She was 74 or 75.

References

Other websites

1945 births
2020 deaths
Cancer deaths in London
Movie actors
Actors from Tehran
Stage actors
Detto Mariano (born Mariano Detto; 27 July 1937 – 25 March 2020) was an Italian musician. He was also a composer, arranger, lyricist, pianist and record producer. His career started in 1958. He is best known as a member of I Ribelli. He was born in Monte Urano, Marche.

On 25 March 2020, during the 2019–20 coronavirus pandemic, Mariano died in Milan due to COVID-19. He was 82.

References

Other websites

 

1937 births
2020 deaths
Deaths from the COVID-19 pandemic in Italy
21st-century Italian composers
Italian songwriters
Italian pianists
Record producers
Movie score composers
20th-century Italian composers
Adriano Celentano (; born 6 January 1938) is an Italian singer-songwriter, musician, actor and movie director. He is known as "il Molleggiato". He was born in Milan. In 1962, Celentano founded the Italian record label Clan Celentano. His best known works are "24.000 Baci", "Il Tuo Bacio e’ Come un Rock" and "Si e’ Spento il Sole".

References

1938 births
Living people
Italian singer-songwriters
Italian musicians
Italian movie directors
Actors from Milan
Eric Weissberg (August 16, 1939 – March 22, 2020) was an American singer, banjo player, and multi-instrumentalist. He was known for his banjo solo in "Dueling Banjos". It was released as a single that reached number 2 in the United States and Canada in 1973. Weissberg was a member of the folk group The Tarriers. Weissberg was born in New York City.

Weussberg died on March 22, 2020 in Detroit, Michigan of Alzheimer's disease-related problems, aged 80.

References

Other websites
 Official Eric Weissberg site 

1939 births
2020 deaths
Deaths from Alzheimer's disease
American guitarists
Country musicians from New York (state)
American country singers
Singers from New York City
Musicians from New York City
ICQ is a cross-platform instant messaging and VoIP client. The name ICQ derives from the English phrase "I Seek You". Originally developed by the Israeli company Mirabilis in 1996, the client was bought by AOL in 1998, and then by Mail.Ru Group in 2010.

The ICQ client application and service were initially released in November 1996, freely available to download. ICQ was among the first stand-alone instant messenger (IM)—while real-time chat was not in itself new (Internet Relay Chat (IRC) being the most common platform at the time), the concept of a fully centralized service with individual user accounts focused on one-on-one conversations set the blueprint for later instant messaging services like AIM, and its influence is seen in modern social media applications. ICQ became the first widely adopted IM platform.
At its peak around 2001, ICQ had more than 100 million accounts registered. At the time of the Mail.Ru acquisition in 2010, there were around 42 million daily users. Since 2013, ICQ has 11 million monthly users.

Microsoft Windows software
Social networking
Twelve people have walked on Earth's Moon. The first one was Neil Armstrong and the last one was Harrison Schmitt. All crewed moon landings took place between July 1969 and December 1972 as part of the United States Apollo program. All twelve people who have walked on the Moon are American men.

List

Related pages
List of Apollo astronauts

References

Apollo astronauts
NASA assigned 32 American astronauts to the Apollo lunar landing program, and 24, flying on nine missions between December 1968 and December 1972, orbited the Moon.

During six two-man landing missions twelve astronauts walked on the lunar surface, and six of those drove Lunar Roving Vehicles. Three flew to the Moon twice, one orbiting both times and two landing once apiece.

Apollo astronauts who walked on the Moon

Apollo astronauts who flew to the Moon without landing

Related pages
 Moonwalkers

References

Apollo astronauts
Apollo astronauts
Thomas Patten Stafford (born September 17, 1930; Lt Gen, USAF, Ret.) is an American former Air Force officer, test pilot, and NASA astronaut.

Stafford commissioned in the United States Air Force, flying the F-86 Sabre prior becoming a test pilot.  

He was selected to become an astronaut in 1962, and flew aboard Gemini 6A and Gemini 9. 

In 1969, Stafford was the Commander of Apollo 10, the second crewed mission to orbit the Moon and the first to fly a Lunar Module in lunar orbit, descending to an altitude of nine miles.

In 1975, Stafford was the commander of the Apollo-Soyuz Test Project flight, the first joint U.S.-Soviet space mission.

References

1930 births
Living people
Apollo astronauts
Scientists from Oklahoma
The Lunar Roving Vehicle (LRV) is a battery-powered four-wheeled rover used on the Moon in the last three missions of the American Apollo program (15, 16, and 17) during 1971 and 1972. They are popularly known as  "Moon buggies", a play on the words "dune buggy".

These three LRVs remain on the Moon.

Other websites
 Boeing Lunar Rover Vehicle Operations Handbook
 Article about the rover
 LRV Operations Handbook, Appendix A (Performance Data)
 Mobility Performance of the Lunar Roving Vehicle:  Terrestrial Studies – Apollo 15 Results

Apollo program
1970s in spaceflight
The Loud House is an American animated television series created by Chris Savino for Nickelodeon. The series premiered on May 2, 2016.

Overview

Episodes

Season 1 (2016)
The first season of The Loud House first aired on May 2, 2016. It ended on November 8, 2016. The DVD for this season was released in Region 1 on May 21, 2017 and in Region 2 on May 22, 2018

Season 2 (2016-17)

Season 3 (2018-19)

Season 4 (2019-20)
The fourth season of The Loud House released on May 27, 2019 with the episode "Friended with the Casagrandes". It ended on July 23, 2020 with the episode "Coupe Dreams".

Season 5 (2020-22)
The fifth season of The Loud House aired on September 11, 2020 with the episode "Schooled!".

Season 6 (2022-23)

Season 7 (2023)

Special (2020)
A special called "The Loud House & Casagrandes Hangin' At Home Special" premiered on May 23, 2020.

Shorts (2014-present)
This is a list of shorts of The Loud House. 1-134 minute episodes.

Related pages
 List of The Casagrandes episodes

References
References 

Lists of animated television series episodes
Lists of Nickelodeon television series episodes
Stuart Allen "Stu" Roosa (August 16, 1933 – December 12, 1994), (Col., USAF), was an American aeronautical engineer, United States Air Force pilot, test pilot, and NASA astronaut. He was the Command Module Pilot for the Apollo 14 mission. He was the third mission to land astronauts (Alan Shepard and Edgar Mitchell) on the Moon. 

While Shepard and Mitchell spent two days on the lunar surface, Roosa made experiments from orbit in the Command Module Kitty Hawk. 

He was one of 24 men to travel to the Moon, which he orbited 34 times.

Roosa died of pancreatitis in Falls Church, Virginia on December 12, 1994 at the age of 61.

References

1933 births
1994 deaths
Deaths from pancreatitis 
Apollo astronauts
American aviators
Engineers from Colorado
Scientists from Colorado
Durango is the county seat and the most populous city of La Plata County, Colorado, United States.  It is home to Fort Lewis College. The United States Census Bureau reported a population of 19,071 in the 2020 census.

References

Cities in Colorado
County seats in Colorado
Bellwood is a village in Proviso Township, Cook County, Illinois, United States. It is  west of Chicago's downtown Loop. The population was 18,789 at the 2020 census.

References

Villages in Illinois
Settlements in Cook County, Illinois
Suburbs of Chicago
Proviso Township is one of 29 townships in Cook County, Illinois, United States.  As of the 2020 census, its population was 151,209.

It was organized in 1850 and originally named "Taylor".

References

Townships in Illinois
Settlements in Cook County, Illinois
Hillside is a village in Cook County, Illinois, United States. As of the 2020 census it had a population of 8,320.

References

Villages in Illinois
Suburbs of Chicago
Settlements in Cook County, Illinois
Maywood is a village in Proviso Township, Cook County, Illinois, United States. It was founded on April 6, 1869. The population was 23,512 at the 2020 United States Census.

References

Villages in Illinois
Suburbs of Chicago
Settlements in Cook County, Illinois
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a 'substantial contribution to the improvement of natural knowledge, including mathematics, engineering science, and medical science.

Isaac Newton was one of the earliest fellows of the Royal Society, elected in 1672
Fellowship of the Royal Society has been described by The Guardian newspaper as “the equivalent of a lifetime achievement Oscar” with several institutions celebrating their announcement each year.

1663
Science awards
Royal Society
British awards‎
A boil is a type of infection. It can cause a skin infection. Most boils can hurt a little bit when touched.

Boils can be treated by putting a hot washcloth on it and will pop after a couple of days.

Diseases caused by bacteria
Hugh Conaghan (6 May 1926 – March 2020) was an Irish Fianna Fáil politician. He was elected to Dáil Éireann as Fianna Fáil Teachta Dála (TD) for the Donegal constituency at the 1977 general election.

He was a losing candidate at the Donegal North-East by-election on 10 June 1976. He was elected at the 1981 general election for the Donegal North-East constituency and was re-elected for this constituency until he lost his seat at the 1989 general election. He was a losing candidate at the 1992 general election.

Conaghan died in March 2020, aged 93.

References

1926 births
2020 deaths
Irish politicians
João Teixeira de Faria (born June 24, 1942), known also as João de Deus (John of God), is a Brazilian medium , "psychic surgeon" and convicted sex offender. His business is set in Abadiânia, Brazil, where he runs the Casa de Dom Inácio de Loyola, a "spiritual healing center". 

He has had media coverage on CNN, ABC News and The Oprah Winfrey Show. James Randi and Joe Nickell had criticized him for his healing procedures as "nothing more than carnival tricks" and there is no evidence that the benefits of patients are placebo effects. 

In 2018, after over 600 people accused him of sexual abuse, he turned himself in to police. In December 2019 he was sentenced to 19 years and four months for the rapes of four different women. On January 20, 2020, Faria was sentenced to another 40 years in prison for rape against 5 women. The sentences add up to 63 years and 4 months.

References

Living people
1942 births
Spirituality
Brazilian writers
People convicted of assault
Sex offenders
Brazilian criminals‎
Dubravka Jurlina Alibegović (born 5 November 1963) is a Croatian economist and politician. She was an independent in the cabinet of Tihomir Orešković. She was the Minister of Public Administration from January to October 2016.

Alibegović was born in Zagreb. She graduated from the Faculty of Economics and Business, University of Zagreb. She was the director of the Institute of Economics, Zagreb from 2013 to 2016.

References

Other websites

Dubravka Jurlina Alibegović profile 

1963 births
Living people
Politicians from Zagreb
Yugoslavian economists
Independent politicians
Joe Nickell (born December 1, 1944) is an American skeptic and investigator of the paranormal. 

He helped find out that the diary of Jack the Ripper was a hoax. In 2002 he was one of a number of experts asked by scholar Henry Louis Gates, Jr. to see if the manuscript of Hannah Crafts' The Bondwoman's Narrative (1853–1860), possibly the first novel by an African-American woman, was real. 

Nickell is senior research fellow for the Committee for Skeptical Inquiry (CSI) and  writes regularly for their journal, the Skeptical Inquirer. 

He is also an associate dean of the Center for Inquiry Institute. He is the author or editor of over 30 books.

References

1944 births
Living people
Skeptics
Writers from Kentucky
Suzanne Dekker (born 31 October 1949) is a former Dutch politician. She was born in Amsterdam. She is a member of Democrats 66 (D66). She sat as a member of the European Parliament (MEP) from the Netherlands between 1979 and 1981. Dekker also served in the Dutch House of Representatives from 1981 to 1982.

References

1949 births
Living people
Democrats 66 politicians
Members of the House of Representatives of the Netherlands
MEPs for the Netherlands
Politicians from Amsterdam
Elsa Lára Arnardóttir (born 30 December 1975) is an Icelandic politician. She is a member of the Progressive Party. From 2013 to 2017, she was a member of the national parliament for the Northwest constituency.

References

1975 births
Living people
Icelandic politicians
Joe Harry Lycett (born 5 July 1988) is a British comedian. He has appeared on television shows including Live at the Apollo, Taskmaster, Never Mind the Buzzcocks, 8 Out of 10 Cats and QI.

He is the announcer on Saturday BBC One show Epic Win, and as the presenter on BBC Two's The Great British Sewing Bee.

He has his own show on Channel 4 titled, Joe Lycett's Got Your Back.

He is openly bisexual.

On 1 March 2020, he announced that he had changed his legal name to Hugo Boss in protest against the company of the same name.

References

1988 births
Living people
English comedians
British television personalities
British LGBT people
LGBT comedians
British LGBT rights activists
Bisexual people
People from Birmingham
William Dufris (February 1, 1958 – March 24, 2020) was an American voice actor and Audiobook narrator. He was born in Houlton, Maine. He was known for English dubbing many foreign language cartoons and animes. His best known work include dubbing Kataoka in Patlabor: The Movie (1989) and its sequel (1993), as Elvis and Dougan in Rocky and the Dodos and as Bob the Builder in the animated children's program.

Dufris died on March 24, 2020 of cancer at the age of 62.

References

Other websites
 

1958 births
2020 deaths
Cancer deaths in the United States
American voice actors
Actors from Maine
Houlton is a town in Aroostook County, Maine, on the Canada–US border, located at . As of the 2010 census, the town's population was 6,123. Houlton is the county seat of Aroostook County, and as such its nickname is the "Shire Town".

References

Towns in Maine
County seats in Maine
Aroostook County () ( ) is a county in the U.S. state of Maine along the Canada–U.S. border. As of the 2020 census, the population was 67,105. Its seat is Houlton.

References

19th-century establishments in Maine
1839 establishments in the United States
Maine counties
Douglas Craig Emhoff (born October 13, 1964) is an American entertainment lawyer. He is the Second Gentleman of the United States, the first ever man to be Second Gentleman. He is the husband of Vice President of the United States Kamala Harris.

He is also the first Jewish spouse to a United States Vice President.

Emhoff is an entertainment litigator and began his career at Pillsbury Winthrop’s litigation group.

Emhoff worked with DLA Piper at their Washington, D.C. and California offices.

Emhoff and Harris have homes in Los Angeles, San Francisco, and Washington, D.C.

Biography
Biography

Early Life, Education & Family 
Emhoff was born in Brooklyn, New York, and raised in Matawan, New Jersey, by his parents, Mike and Barbara, with his siblings, Jamie and Andy. His family moved to the Los Angeles area during his teen years. Mr. Emhoff earned a B.A. from California State University, Northridge and a J.D. from University of Southern California Gould School of Law. He and the Vice President have been married for eight years and are the proud parents of Cole and Ella Emhoff.

Second Gentleman of the United States (2021–present) 
Emhoff assumed the role and duties as the second gentleman of the United States succeeding Karen Pence, when his wife was inaugurated as the 49th vice president of the United States on January 20, 2021.

Emhoff is the first male spouse of a Vice President. As Second Gentleman, he helped raise awareness of growing antisemitism.

References
References

1964 births
Living people
Lawyers from New York City
Second Spouses of the United States
Businesspeople from New York City
Businesspeople from Washington, D.C.
Kamala Harris
Uncut Gems is a 2019 American thriller movie directed by Josh and Benny Safdie, who co-wrote the screenplay with Ronald Bronstein.

The movie stars Adam Sandler as Howard Ratner, a Jewish jeweler and gambling addict in New York City, who must get an expensive gem he purchased to pay off his debts. The movie also stars Kevin Garnett, Idina Menzel, Lakeith Stanfield, Julia Fox, and Eric Bogosian.

Uncut Gems had its world premiere at the Telluride Film Festival on August 30, 2019. It had a wide release on December 25, by A24. The movie strong good reviews, with its screenplay, direction, editing and Sandler's performance.

It was chosen by the National Board of Review as one of the top ten movies of 2019.

References

2019 movies
Movies set in New York City
American mystery movies
American thriller movies
American sports movies
Netflix movies
Carlo Lorenzini (24 November 1826 – 26 October 1890), better known by the pen name Carlo Collodi (), was an Italian author, humorist, and journalist, widely known for his fairy tale novel The Adventures of Pinocchio.

References

1826 births
1890 deaths
Italian journalists
Children's writers
Writers from Florence
Alfred Gomolka (21 July 1942 – 24 March 2020) was a German politician. He was a Member of the European Parliament for Mecklenburg-Vorpommern from 1994 to 2008. He was a member of the conservative Christian Democratic Union of Germany, part of the European People's Party. He was the first Minister President of Mecklenburg-Vorpommern from 1990 to 1992 and was the President of the Bundesrat from 1 November 1991 to 19 March 1992.

Gomolka died on 24 March 2020 from a fall in Schwerin, Mecklenburg-Vorpommern, aged 77.

References

Other websites
 Website of Alfred Gomolka
 CV at the European Parliament website

1942 births
2020 deaths
Accidental deaths from falls
MEPs for Germany
"Blinding Lights" is a song by Canadian recording artist The Weeknd, taken from his seventh studio album, After Hours.  The song was released on November 29, 2019, two days after the album’s lead single, “Heartless”.  “Blinding Lights” was written and produced by The Weeknd, Max Martin, and Oscar Holter. DaHeala and Belly also contributed to writing the song.

The song has topped charts in thirteen countries. It became his fifth number-one single on the US Billboard Hot 100.

On November 23, 2021, Billboard announced that it had overtaken "The Twist" by Chubby Checker as the best-performing song in Billboard history.

Charts

All-time charts

References 
2019 songs
New wave

The Weeknd
James Patrick Otis (March 16, 1948 – March 3, 2020) was an American actor. He was born in Stamford, Connecticut. Otis began his career in the 1970s. His first movie role was in Dragonfly. On television, he was known for his role in Profiler.

In 1999, Otis appeared in three episodes of Star Trek: Deep Space Nine. In 2006, Otis appeared in the true story movie The Black Dahlia. Otis also appeared in The Prestige.

Otis died in Stamford on March 3, 2020 at the age of 71.

References

Other websites

American movie actors
American stage actors
American television actors
Actors from New York City
1948 births
2020 deaths
Actors from Stamford, Connecticut
David Greetham (October 21, 1941 – March 24, 2020) was an English-American literary critic. He was known as the founder of the Society for Textual Scholarship. He was the Society's President from 1999 to 2001. He worked at the Graduate Center at City University New York. Greetham was born in Cheshire, England.

Greetham died on March 24, 2020 from a long-illness at the age of 78.

Works
 The Pleasures of Contamination (2010)
 Theories of the Text (1999)
 Textual Transgressions: Essays Toward the Construction of a Biobibliography (1998)
 The Margins of the Text: Editorial Theory and Literary Criticism (1997)
 Scholarly Editing: A Guide to Research (1995)
 Textual Scholarship: An Introduction (1992)
 TEXT: An Interdisciplinary Annual of Textual Studies (1984)

References

2020 deaths
Writers from Cheshire
1941 births
Naturalized citizens of the United States
American literary critics
American essayists
Writers from Massachusetts
People from Lenox, Massachusetts
Peter Green (born Peter Allen Greenbaum; 29 October 1946 – 25 July 2020) was a British blues rock singer-songwriter and guitarist. He is one of the founders of Fleetwood Mac. He was added to the Rock and Roll Hall of Fame in 1998. Green's writing credits include Fleetwood Mac songs such as "Albatross", "Black Magic Woman", "Oh Well", "The Green Manalishi (With the Two Prong Crown)" and "Man of the World". Rolling Stone ranked Green at number 58 in its list of the "100 Greatest Guitarists of All Time".

Green was born in Bethnal Green, London. His family were Jewish. Green was married to Jane Samuels from 1978 to 1979. The couple had one daughter.

Green lived on Canvey Island in Essex. On 25 July 2020, Green died in his sleep at the age of 73.

References

Other websites

1946 births
2020 deaths
Blues guitarists
English rock guitarists
English rock singers
Jewish British musicians
Fleetwood Mac members
Singer-songwriters from London
Rock and Roll Hall of Fame inductees
John Griffith Davies (17 May 1929 – 24 March 2020) was an Australian-American breaststroke swimmer and politician.

Davies won a gold medal in the 200-metre breaststroke at the 1952 Summer Olympics in Helsinki and set a world record in the 200 yard breaststroke (short course) and tied the world record in the 200 m breaststroke (long course). 

After retiring from competition swimming, he became a lawyer in California. He was appointed a United States District Judge of the United States District Court for the Central District of California by President Ronald Reagan in 1986.r He presided over the trial of the Los Angeles Police Department officers charged with assaulting Rodney King. He retired from the court in 1998.

Davies was born in Willoughby, New South Wales, Australia. He studied at the University of Michigan and at the University of California at Los Angeles. He moved to the United States in 1955.
Davies was added into the International Swimming Hall of Fame in 1984, and the Sport Australia Hall of Fame in 1992.  He received an Australian Sports Medal in 2000.

Davies died of cancer in Pasadena, California on 24 March 2020, aged 90.

References

1929 births
2020 deaths
Cancer deaths in California
Naturalized citizens of the United States
Australian Olympic gold medalists
Australian swimmers
American judges
Lawyers from Los Angeles
Sportspeople from New South Wales
Politicians from Los Angeles
Republican Party (United States) politicians
Lawrence Pressman (born David M. Pressman; July 10, 1939) is an American actor. He is best known for roles on Doogie Howser, M.D., Ladies' Man, Profiler, Mulligan's Stew and in the 1971 movie The Hellstrom Chronicle.

References

Other websites

1939 births
Living people
American movie actors
American television actors
American stage actors
Actors from Kentucky
Lucien Sève (9 December 1926 – 23 March 2020) was a French philosopher, communist and political activist. He was born in Chambéry, France. He was an active member of the French Communist Party from 1950 through 2010. He was elected as a member of the Central Committee in 1961, and stayed elected until 1994. His 1969 work Marxisme et théorie de la personnalité (Marxism and theory of personality) has been translated into 25 different languages. 

Sève died on 23 March 2020 of COVID-19 in Clamart, France, aged 93.

References

Other websites
 BNF

1926 births
2020 deaths
French philosophers
French political writers
French communists
Deaths from the COVID-19 pandemic in France
People from Chambéry
Writers from Auvergne-Rhône-Alpes
Clamart () is a commune in the southwestern suburbs of Paris, France. It is located  from the center of Paris.

References

Other websites
 Official website  
 New residents' welcome website  

Communes in Hauts-de-Seine
Ann Dustin Wilson (born June 19, 1950) is an American musician. She rose to fame as the lead singer and songwriter rock band Heart. Her younger sister, Nancy Wilson, is Heart's guitarist. As a member of Heart, Wilson was added to the Rock and Roll Hall of Fame in 2013.

Wilson was born in San Diego, California. Her family later settled in Bellevue, Washington. She has two children. She married Dean Wetter in 2015.

References

Other websites

1950 births
Living people
American rock singers
Musicians from San Diego, California
Musicians from Washington
Rock and Roll Hall of Fame inductees
Singer-songwriters from California
Nancy Lamoureaux Wilson (born March 16, 1954) is an American musician and singer. She is best known as a guitarist and backing vocalist for the rock band Heart. Her older sister, Ann Wilson, is Heart's lead singer. As a member of Heart, Wilson was added to the Rock and Roll Hall of Fame in 2013.

Wilson was born in San Francisco, California. Her family moved to Federal Way, WA then later settled in Bellevue, Washington. She has two children with her first husband Cameron Crowe. She is now married to Geoff Bywater.

References

Other websites

1954 births
Living people
American rock guitarists
American rock singers
Musicians from San Francisco
Musicians from Washington
Rock and Roll Hall of Fame inductees
Nancy Wilson may refer to:

 Nancy Wilson (jazz singer) (1937–2018), American jazz singer and actress
 Nancy Wilson (religious leader) (born 1950), American cleric
 Nancy Wilson (rock musician) (born 1954), American rock singer and guitarist
 Nancy Wilson (basketball) (born 1969), American professional and college basketball coach
 Nancy Wilson (journalist), Canadian television journalist
A self-help book  is written in a way that its reader can relate to himself/herself and solve his/her problems as guided by the author of the book.

A self-help book is written to counsel its readers on solving their personal issue or problems in life. The phrase "Self-Help" comes from an 1859 best-seller by Samuel Smiles.  "Self-improvement" is a modern version of the term self-help.

References

Self-help books
BC Transit is a transit company run by the British Columbian government that gives bus services to many towns and areas in the province.

Before 1979, the power company, BC Hydro, ran the buses. In 1979, the province made the transit company into a separate agency called the Urban Transit Authority which became BC Transit in 1983.

BC Transit transit plans the routes and schedules but doesn't run the buses in most of the province. In 1999, a new company called TransLink was made to run the buses, metro, and trains in Vancouver. BC Transit might give more areas to TransLink one day.

History

A company called the BC Electric Railway was made in 1897 to replace the Consolidated Railway Company, which had run the streetcars in Victoria, Vancouver and New Westminster. Slowly the streetcars and interurban trains were changed to electric trolley and gas-powered buses. The province made BC Hydro in 1962 to take over when the old company ran out of money.
In 1979, the government made the Urban Transit Authority, to plan and make rules for public transit; and the Metro Transit Operating Company, a separate crown corporation that actually ran the buses. The new structure was meant to provide local governments with more decision-making power and funding of their local systems. BC Transit was in 1982.

In 1999, Vancouver's transit system started to be controlled by a difference company, TransLink.

In 2018, BC Transit started running its first intercity buses in Northern British Columbia after Greyhound Canada stopped running buses in the province. In 2019, drivers got safety doors to stop people from hurting them. During the COVID outbreak in March 2020, BC Transit made buses free everywhere in the province and let people get on in the back door. This lasted until June 1, 2020.
Transit systems
The Victoria Regional Transit System, in the capital, is the only system where the buses are run by BC Transit. Outside Victoria, the bus schedules and routes are made by BC Transit but the buses are driven by other companies. In four places (Nanaimo, Nelson, Powell River, and the Sunshine Coast) the towns run the buses.

HandyDART

BC Transit runs buses for people who have difficulty getting around. These buses are called paratransit and people call for the service to pick them up and drop them off ahead of time.

Health Connections

Because lots of small towns don't have hospitals and doctors, there are also some buses that run from small towns into big cities. These buses don't run often, but they're still very important.

References

Companies based in British Columbia
Transport companies
These are characters that appear in the Arthur book series and the TV show.

Read Family 
Arthur Read (Pamela Adlon) - The main character of the show. Francine has a crush on Arthur. Francine will marry Arthur sometime in the future. Arthur is an aardvark.
Jane Read (Tress MacNeille) - Arthur’s mother. She is also the mother of Arthur’s sister, D.W.
David Read (Rob Paulsen) - Arthur’s father/dad. He is also the father of Arthur’s sister, D.W.
D.W. Read (Mary Kay Bergman; April Stewart) - D.W. is Arthur’s sister. She usually tattles on her brother Arthur. Her full name is Dora Winifred Read. Once, Arthur punched D.W. in the arm.
Kate Read (Kath Soucie) - Arthur's youngest sister. Has a special relationship with Pal the puppy.

Baxter Family 
Buster Baxter (Tom Kenny) - Arthur’s best friend. He is a rabbit. In one episode, Buster was dared to kiss Francine, and when he did do it, she ran after him. He loves to eat junk food.
Frensky Family 
Francine Frensky (Mary Kay Bergman; Cree Summer) - One of the best friends of Arthur. Francine has a crush on Arthur. She will marry Arthur. She is a tomboy and a monkey.

Bulldog Family 
Binky Bulldog (Bruce Dinsmore) - A bulldog in 4th grade. In Buster and the Daredevils, Binky threw a milkshake at Buster after he was dared to tell him his “mother eats gym shorts”. He has a deep voice in Seasons 1-8 (1996-2003).

References 

Lists of fictional characters
"Arthur's Big Hit" is the first episode in season 4 of Arthur. It first aired on October 4, 1999. In this episode, Arthur punches D.W.

Eventually, the scene where Arthur punched D.W. becomes a very popular meme.

Plot 
It starts off with Arthur showing flashbacks when he got very mad at D.W. Next, Arthur is trying to build his toy airplane and tells D.W. to not touch or mess with it. He is walking around in the living room until he hears his airplane fall to the ground.
Later, D.W. says his airplane can’t fly at all. Then, Arthur goes outside with D.W. only to found out his plane broke. Later, Arthur furiously says to D.W. "I told you NOT TO TOUCH IT!" and angrily punches her in the arm. A few seconds after she falls to the ground, D.W. cries and goes to Jane Read. She says to Arthur: "Arthur Timothy Read, come here!". Arthur then says, "Uh-oh. Middle name." After that, his mother carries Arthur and tells him, “Apologize to your sister now!" but Arthur says no. In the living room, his dad tells Arthur: "Arthur, this means no TV for a week."

Arthur tells his parents it is not fair. Later at school, Arthur tells all his friends. Eventually, the tough customers tell Binky to punch Arthur in the arm the next time he sees him.
Binky does not want to, so he comes up with a plan not to look at Arthur ever again. However, while walking with his friends, Binky sees Arthur at the playground and they tell him to punch him. Then, he gives into the peer pressure and punches Arthur in the arm and Arthur runs home. Later, he apologizes to D.W. and their relationship goes back to normal.

References 

Arthur (TV series)
1999 television episodes
Bethalto is a village in Illinois in the United States.

Villages in Illinois
Bradford is a village in Illinois in the United States.

Villages in Illinois
An unclaimed person is someone who is dead and none of their family members have seen the dead body or if the dead person have no family members who are alive.

In most states, almost 40,000 unclaimed bodies have been found and put in a morgue.

References 

People
Bartonville is a village in Illinois in the United States.

Villages in Illinois
Gladstone is a village in Illinois in the United States.

Villages in Illinois
Elvaston is a village in Illinois in the United States.

Villages in Illinois
Atkinson is a town in Illinois in the United States.

Towns in Illinois
Avon is a village in Illinois in the United States.

Villages in Illinois
Bishop Hill is a village in Illinois in the United States.

Villages in Illinois
Bardolph is a village in Illinois in the United States.

Villages in Illinois
Dongola is a village in Illinois in the United States.

Villages in Illinois
Mill Creek is a village in Illinois in the United States.

Villages in Illinois
East Carondelet is a village in Illinois in the United States.

Villages in Illinois
Fairmont City is a village in Illinois in the United States.

Villages in Illinois
Crestwood is a village in Illinois in the United States.

Villages in Illinois
Suburbs of Chicago
Settlements in Cook County, Illinois
Lenzburg is a village in Illinois in the United States.

Villages in Illinois
Sauget is a village in Illinois in the United States.

Villages in Illinois
Tamaroa is a village in Illinois in the United States.

Villages in Illinois
Bartelso is a village in Illinois in the United States.

Villages in Illinois
Bartlett is a village in Illinois in the United States. In 2020, 41,105 people lived there.

References

Villages in Illinois
Suburbs of Chicago
Settlements in Cook County, Illinois
Settlements in DuPage County, Illinois
Carol Stream is a village in Illinois in the United States.

Villages in Illinois
Suburbs of Chicago
Settlements in DuPage County, Illinois
Adams County is a county in Washington in the United States. The county seat is Ritzville. At the 2020 census, 20,613 people lived there.

References

19th-century establishments in Washington (state)
1883 establishments in the United States
Washington (state) counties
Grant County is a county in Washington in the United States. The county seat is Ephrata. At the 2020 census, 99,123 people lived there.

References

20th-century establishments in Washington (state)
1909 establishments in the United States
Washington (state) counties