Aarushhh/wikipedia-simple-splitted huggingface dataset:
Linda Bloodworth-Thomason, screenwriter, Designing Women, Evening Shade
 Andrea Bogart (born 1977), actress, General Hospital
 Johnny Yong Bosch (born 1976), singer, actor, Eyeshine, Trigun, Power Rangers
 Jeff Branson (born 1977), actor
 Brent Briscoe (born 1961), actor, Yes Man, National Treasure: Book of Secrets, Spider-Man 2
 Kent Broadhurst (born 1940), actor
 Norbert Leo Butz (born 1967), Tony Award-winning stage actor
 Morris Carnovsky (1897–1992), actor, Edge of Darkness, Dead Reckoning
 Conlan Carter (born 1934), actor, Combat!, The Law and Mr. Jones
 Don Cheadle (born 1964), actor, Hotel Rwanda, Traffic, Boogie Nights, The Rat Pack
 Anthony Cistaro (born 1963), actor, Charmed, Witchblade
 Sarah Clarke (born 1972), actress, Nina Myers on 24
 Lynn Cohen, actress, Law & Order, Sex and the City
 Frank Converse (born 1938), actor, Movin' On, N.Y.P.D.
 Chris Cooper (born 1951), Oscar-winning actor, Lonesome Dove, The Bourne Identity, American Beauty, The Muppets
Joan Crawford (1905–1977), Oscar-winning actress, Mildred Pierce
 Greg Cromer (born 1971), actor
 Robert Cummings (1908–1990), actor, Kings Row, Saboteur, Dial M for Murder
Erin Daniels (born 1973), actress, The L Word
 Don S. Davis (1942–2008), actor, Stargate SG-1, Twin Peaks
 Kurt Deutsch, actor, Models Inc.
 Walt Disney (1901–1966), iconic film and television producer, studio mogul, director, screenwriter, voice actor and animator
 Dale Dye (born 1944), actor, Saving Private Ryan, Mission: Impossible, Band of Brothers
 Cliff Edwards (1895–1971), actor, musician; the voice of Jiminy Cricket
 Jenna Fischer (born 1974), actress, The Office, Hall Pass, Blades of Glory
 Henderson Forsythe (1917–2006), actor, As the World Turns
 James Franciscus (1934–1991), actor, Mr. Novak, Naked City, Longstreet
 Phyllis Fraser (1915–2006), actress, journalist, children's book publisher, wife of Bennett Cerf and Robert F. Wagner, Jr.
 Friz Freleng (1905–1995), film producer, director, screenwriter, and animator, Looney Tunes, Merrie Melodies
 Bob Gale (born 1951), screenwriter, the Back to the Future trilogy
 Betty Garrett (1919–2011), actress, On the Town, Laverne & Shirley
Heather Goldenhersh (born 1973), actress, The Class, School of Rock
 John Goodman (born 1952), actor, Roseanne, The Babe, Barton Fink, Oh Brother Where Art Thou, Monuments Men
 Lucas Grabeel (born 1984), actor, High School Musical, Milk
 Betty Grable (1916–1973), actress, singer and World War II pin-up girl
Bryan Greenberg (born 1978), actor, musician, One Tree Hill, October Road, How to Make It in America
 Dabbs Greer (1917–2007), actor, Little House on the Prairie, Gunsmoke, Picket Fences
 Eddie Griffin (born 1968), actor, comedian, Undercover Brother, Norbit
 Davis Guggenheim (born 1963), director, producer
 Robert Guillaume (born 1927), actor, Benson, The Lion King, Sports Night
 James Gunn (born 1970), film director and screenwriter
 Sean Gunn (born 1974), actor, Gilmore Girls, October Road
 Moses Gunn (1929–1993), actor, Father Murphy, The Cowboys, A Man Called Hawk
Jon Hamm (born 1971), actor, Mad Men, The Town, Million Dollar Arm
 Jean Harlow (1911–1937), actress and sex symbol
 George Hearn (born 1934), actor, primarily Broadway and musical theatre
 George Hickenlooper (1965–2010), documentary filmmaker, Hearts of Darkness, Dogtown
 Dennis Hopper (1936–2010), actor, filmmaker, artist, Easy Rider, Apocalypse Now, Hoosiers
 Arliss Howard (born 1954), actor, writer and director, Full Metal Jacket, Wilder Napalm, Moneyball
 Rupert Hughes (1872–1956), film director, composer; uncle of reclusive billionaire Howard Hughes
 John Huston (1906–1987), actor and Oscar-winning film director, The Maltese Falcon, Key Largo, The African Queen
 Don Johnson (born 1949), actor, Miami Vice, Nash Bridges, Django Unchained
 Jay Johnson (born 1977), actor The Young and the Restless, Scrubs
 Janet Jones (born 1961), actress, dancer, wife of hockey's Wayne Gretzky
 Neal Jones (born 1960), actor, Dirty Dancing, G.I. Jane
Brenda Joyce (1917–2009), actress, Little Tokyo, U.S.A., Tarzan movies in the 1940s
 Andreas Katsulas (1946–2006), actor, Babylon 5, Star Trek: The Next Generation
 Ellie Kemper (born 1980), actress The Office
 Edward Kerr (born 1966), actor, seaQuest DSV, What I Like About You
 Lincoln Kilpatrick (1932–2004), actor
 Kevin Kline (born 1947), Oscar-winning actor, Sophie's Choice, The Big Chill, A Fish Called Wanda, Last Vegas
 Evalyn Knapp (1906–1981), actress, Perils of Pauline
 David Koechner (born 1962), actor and comedian, Saturday Night Live, Anchorman
 Kasi Lemmons (born 1961), actress and director, Eve's Bayou, Talk to Me
 Angela Lindvall (born 1979), actress
 Mark Linn-Baker (born 1954), actor, My Favorite Year, Larry Appleton on Perfect Strangers
 Marsha Mason (born 1942), actress, Sibs, The Goodbye Girl, Only When I Laugh, Frasier
 Michael Massee (born 1955), actor, 24, Seven, The Crow,
 Wendell Mayes (1919–1992), screenwriter, The Spirit of St. Louis, North to Alaska, Von Ryan's Express
Virginia Mayo (1920–2005), actress, The Best Years of Our Lives, White Heat
 Edie McClurg (born 1951), actress, Ferris Bueller's Day Off, 7th Heaven
 Frank McGrath (1903–1967), actor, Wagon Train
 Steve McQueen (1930–1980), actor, The Sand Pebbles, The Great Escape, The Towering Inferno, Bullitt
 John Milius (born 1944), screenwriter, director, producer, Red Dawn, The Hunt for Red October, Conan the Barbarian
 Mircea Monroe, actress, model, Cellular, Episodes
Dustin Nguyen (born 1962), actor, 21 Jump Street, V.I.P.
 Eva Novak (1898–1988), actress of the silent film era, The King of the Kitchen
 Jane Novak (1896–1990), actress of the silent film era, Treat'Em Rough, Redskin
 Dan O'Bannon (born 1946), film director and screenwriter, Heavy Metal, Total Recall
 Denis O'Hare (born 1962), actor, Brothers & Sisters, Sweet Charity, True Blood
 Kevin O'Morrison (born 1916), actor and playwright
 Timothy Omundson (born 1969), actor, Psych, Judging Amy
 Holmes Osborne (born 1947), actor
 Diana Ossana, screenwriter, Brokeback Mountain, Pretty Boy Floyd
 Geraldine Page (1924–1987), Oscar-winning actress, Summer and Smoke, Sweet Bird of Youth, The Trip to Bountiful
 Carlos Pena, Jr. (born 1989), actor, singer, and dancer, Big Time Rush
 Evan Peters (born 1987), actor, American Horror Story, Invasion, Kick-Ass
 Julie Piekarski (born 1963), actress, The Facts of Life
 Brad Pitt (born 1963), actor and producer, Thelma & Louise, 12 Monkeys, Seven, Moneyball, World War Z
William Powell (1892–1984), actor, The Thin Man, Life with Father, My Man Godfrey
 Vincent Price (1911–1993), actor, Laura, House of Wax, The Ten Commandments, The Fly
 Sally Rand (1904–1979), burlesque dancer, actress
 Leonard Roberts (born 1972), actor, Heroes, Buffy the Vampire Slayer
 Ginger Rogers (1911–1995), Oscar-winning actress, dance partner of Fred Astaire
 Sol Smith Russell (1848–1902), 19th Century stage actor
 Phyllis Smith (born 1951), actress, The Office
 Kelly Stables (born 1978), actress, The Exes, W.I.T.C.H., Two and a Half Men
 Craig Stevens (1918–2000), actor, State Trooper, Peter Gunn
 Christian Stolte (born 1962), actor, Prison Break
 Skyler Stone (born 1979), actor, Raising Hope, The Island
 Betty Thomas (born 1948), actress and director, Hill Street Blues, The Brady Bunch Movie, Dr. Dolittle, Private Parts
 Kay Thompson (1909–1998), actress, Funny Face
 William Traylor (1930–1989), actor Fletch, and founder of The Loft Studio/acting school
Kathleen Turner (born 1954), actress, Body Heat, Romancing the Stone, Prizzi's Honor
 Stephen Barker Turner (born 1968), actor
 Dick Van Dyke (born 1925), actor, The Dick Van Dyke Show, Mary Poppins, Diagnosis: Murder
 Jerry Van Dyke (born 1931), actor, Coach, McLintock!, The Courtship of Eddie's Father
 Jack Wagner (born 1959), actor/singer Melrose Place, General Hospital
 Dennis Weaver (1924–2006), actor, Gunsmoke, McCloud
 Jason Wiles (born 1970), actor, Third Watch, Persons Unknown
 Mykelti Williamson (born 1960), actor, Forrest Gump, Con Air, 24, Midnight Caller
 Jane Wyman (1914–2007), Oscar-winning actress; former wife of Ronald Reagan
Comedians

 Cedric The Entertainer (born 1964), actor, comedian
 Redd Foxx (1922–1991), comedian, starred in Sanford and Son
 Dick Gregory (born 1932), comedian, social activist
 Craig Kilborn (born 1962), comedian, actor, former talk show host
 Kathleen Madigan (born 1965), comedienne
 Kevin Nealon (born 1953), actor, comedian
 Randy and Jason Sklar (born 1972), identical twin comedians, hosts of ESPN Classic's Cheap Seats
 Guy Torry (born 1969), actor, comedian
 Joe Torry (born 1965), actor, comedian

Cartoonists
Cartoonists

 Ralph Barton (1891–1931), cartoonist
 George Booth (born 1926), cartoonist for The New Yorker
 Teresa Burritt  (born 1916), cartoonist, Frog Applause, Shoecabbage
 Lee Falk (1911–1999), cartoonist, The Phantom, Mandrake the Magician
 Al Hirschfeld (1903–2003), caricaturist and cartoonist known for drawing celebrities
 Fred Lasswell (1916–2001), cartoonist, Barney Google and Snuffy Smith
 Glenn McCoy (born 1965), cartoonist, The Duplex, The Flying McCoys
 George McManus (1884–1954), cartoonist, Maggie and Jiggs
 Mike Peters (born 1943), cartoonist, Mother Goose & Grimm
 Dan Piraro (born 1958), cartoonist, Bizarro
 Mort Walker (born 1923-2018), cartoonist, Beetle Bailey

Magicians and mentalists

 Morgan Strebler (born 1976), magician and mentalist; Las Vegas award-winning performer

Music

Bluegrass and country
Lennie Aleshire (1890–1987), country-bluegrass pioneer and vaudeville act
 Helen Cornelius (born 1941), country singer best known for duets with Jim Ed Brown
 Rusty Draper (1923–2003), country and rockabilly singer/guitarist
 Sara Evans (born 1971), country music star
 Tyler Farr, country music singer and songwriter
 Bob Ferguson (music) (1927–2001), country music songwriter and producer
 John Hartford (1937–2001), country and bluegrass music composer and performer
 Ferlin Husky (1925–2011), singer and member of the Country Music Hall of Fame
 Brett James, country music singer-songwriter and record producer
 The Kendalls, Grammy-winning country duo from the 1970s and 1980s
 Tom Shapiro, country music songwriter and record producer
 Tate Stevens, country music singer and 2012 winner of The X Factor
 Wynn Stewart (1934–1985), country music singer, progenitor of the Bakersfield sound
 Jamie Teachenor (born 1980), country and rock singer-songwriter, musician and record producer
Trent Tomlinson (born 1975), country singer-songwriter
 Leroy Van Dyke (born 1929), country singer best known for "The Auctioneer" and "Walk on By"
 Darrin Vincent (born 1970), half of the Grammy-nominated bluegrass group Dailey & Vincent; record producer
 Rhonda Vincent (born 1962), bluegrass singer and musician, seven-time IMBA Female Vocalist of the Year
 Porter Wagoner (1927–2007), Grand Ole Opry member and Country Music Hall of Famer
Jazz 

 Oleta Adams (born 1953), soul, jazz and gospel singer
 Ahmad Alaadeen (born 1934), jazz saxophonist and composer
 Norman Brown (born 1970), smooth jazz musician
 Jimmy Forrest (1920–1980), jazz tenor saxophonist
 Coleman Hawkins (1904–1969), jazz tenor saxophonist
 Bob James (born 1939), smooth jazz musician
 Scott Joplin (1867–1917), ragtime musician and composer
 Pat Metheny (born 1954), jazz guitarist and musician
 Lennie Niehaus (born 1929), alto saxophonist, arranger, and composer
 Charlie "Bird" Parker (1920–1955), jazz saxophonist and composer
 David Sanborn (born 1945), smooth jazz musician
 Wilbur Sweatman (1882–1961), Dixieland jazz and ragtime composer and bandleader
 Clark Terry (1920–2015), swing and bebop trumpet and flugelhorn player

Rhythm & blues, pop, rap and hip-hop
Akon (born 1977), rhythm and blues musician, music producer
 Fontella Bass (1940–2012), singer best known for 1965 hit Rescue Me
 Basement Beats, multi-platinum Grammy Award-winning production team
 Chingy (born 1980), rapper, actor
 Eminem (born 1972), rap musician, grew up partly in St. Joseph
 Nelly (born 1974), rap musician, (born in Texas and raised in St. Louis)
 David Peaston (1957–2012), R&B and Gospel singer
 St. Lunatics, hip hop, best known for collaborations with Nelly
 Tech N9ne (born 1971), rapper
 Kimberly Wyatt, singer and dancer, Pussycat Dolls

Rock & roll
Chuck Berry (born 1926), musician in Rock & Roll Hall of Fame
 The Bottle Rockets (formed 1992), rock, alt-country, roots rock
 T Bone Burnett (born 1948), musician, songwriter, and soundtrack and record producer
 Cavo, hard rock band (formed in St. Louis)
 David Cook (born 1982), 2008 American Idol winner from Blue Springs
 Sheryl Crow (born 1962), Grammy-winning singer-songwriter
 Gravity Kills, industrial rock band, formed in Jefferson City
 Johnnie Johnson (1924–2005), early rock & roll and blues piano player; member of Rock & Roll Hall of Fame
 King's X, hard rock, progressive metal band, formed in Springfield
 Michael McDonald (born 1952), singer, former Doobie Brothers frontman
 Missouri, band known for classic rock song "Movin' On", formed in Kansas City
 Ozark Mountain Daredevils, rock band known for hits "Jackie Blue" and "If You Wanna Get To Heaven", formed in Springfield
 Louise Post, founder, lead singer and guitarist of alternative rock band Veruca Salt
Puddle of Mudd, rock band, formed in Kansas City
 The Rainmakers, rock band, formed in Kansas City
 Jay Reatard (1980–2010), garage punk musician, born in Lilbourn
 Wes Scantlin (born 1972), lead singer and guitarist of post-grunge band Puddle of Mudd
 Shooting Star, 1970s and 1980s rock band, from Kansas City
 Story of the Year, emo rock band, formed in St. Louis
 The Urge, rock band, formed in St. Louis
 Bob Walkenhorst, founder and lead singer of alternative rock band The Rainmakers
 Steve Walsh (born 1951), lead vocalist, songwriter and keyboardist for the progressive rock group Kansas and Streets
Miscellaneous other music 

 Doris Akers (1923–1995), gospel music singer and composer
 Martha Bass (1921–1998), gospel singer with the Clara Ward Singers and solo career
 Burt Bacharach (born 1928), pianist, composer
 Neal E. Boyd (born 1975), opera vocalist, winner of 2008 America's Got Talent competition
 Grace Bumbry (born 1937), opera soprano
 Sarah Caldwell (1924–2006), opera conductor
 Sara Groves (born 1972), Contemporary Christian singer, record producer, and author
 Dan Landrum (born 1961), hammer dulcimer player, featured instrumentalist with Yanni
 Basil Poledouris (1945–2006), film soundtrack composer
 H. Owen Reed (born 1910), composer and conductor
 Willie Mae Ford Smith (1904–1994), Gospel singer

Radio and television
Bob Barker (born 1923), television game show host
 Jim Bohannon (born 1944), radio talk show host
 Rush Limbaugh (born 1951), political commentator
 Dana Loesch (born 1978), radio talk show host and editor-in-chief of Andrew Breitbart's Big Journalism
 Melanie Morgan (born 1956), radio personality with KSFO in San Francisco
 "Mancow" Muller (born 1966), radio and TV personality, Mancow's Morning Madhouse
 Marlin Perkins (1905–1986), zoologist and host of Mutual of Omaha's Wild Kingdom
 April Scott (born 1979), model, Deal or No Deal and SOAPnet's Soap Talk

Beauty pageant titleholders

 Debbye Turner (born 1965), Miss America 1990
 Shandi Finnessey (born 1978), Miss USA 2004

Journalism
Jabari Asim (born 1962), author, journalist
 Joe Buck (born 1969), sportscaster for Fox Sports
 Harry Caray (1914–1998), Hall of Fame baseball broadcaster
 Walter Cronkite (1916–2009), television journalist
 Walker Evans (1903–1975), photojournalist best known for photos taken during the Great Depression
 Joe Garagiola, Sr. (born 1926), MLB catcher, baseball broadcaster, and television host (The Today Show)
 Dave Garroway (1913–1982), first host of NBC's Today show
 Michael Kim (born 1964), sports broadcaster for ESPN
 Carol Platt Liebau, attorney, political analyst and social conservative commentator
 Mary Margaret McBride (1899–1976), female radio pioneer
 Dan McLaughlin (born 1974), sportscaster for Fox Sports Midwest
 Russ Mitchell (born 1960), TV journalist, CBS Evening News
 Lisa Myers (born 1951), TV journalist, NBC Nightly News
 Stone Phillips (born 1954), TV journalist, Dateline NBC
 Joseph Pulitzer (1847–1911), Hungarian journalist, creator of the St. Louis Post-Dispatch and the Pulitzer Prize
William T. Anderson (1838–1864), a.k.a. "Bloody Bill" Anderson; Confederate guerrilla leader in the Civil War
 Charles D. Barger (1892–1936), earned the Medal of Honor in World War I
 John L. Barkley (1895–1966), earned the Medal of Honor in World War I
 Frederick Benteen (1834–1898), best known for role under George Custer at the Battle of the Little Bighorn
 Omar Bradley (1893–1981), World War II general, from Clark, Missouri
 Robert Coontz (1864–1935), US Navy Admiral, former Chief of Naval Operations
 John V. Cox (born 1930), United States Marine Corps Major General; flew over 200 combat missions during the Vietnam War
 Enoch Crowder (1859–1932), US Army General and reformer of military justice system
 Randall "Duke" Cunningham, only U.S. Navy Ace in the Vietnam War; later a U.S. Congressman from California
 James Phillip Fleming (born 1943), USAF pilot; awarded the Medal of Honor for actions during the Vietnam War
John C. Fremont (1813–1890), Western explorer; Union Civil War general; first Republican candidate for U.S. President
 Frederick Dent Grant (1850–1912), U.S. Army Major General and diplomat; son of U.S. President Ulysses S. Grant
 Martin E. Green (1815–1863), Confederate Army Brigadier General; killed at Siege of Vicksburg
 John McNeil (1813–1891), Union Army brigadier general during the American Civil War; known as "The Butcher of Palmyra"
 Wayne E. Meyer (1926–2009), U.S. Navy Rear Admiral; "father of the Aegis weapons system"
 David Moore (1817–1893), Mexican–American War officer and Union Civil War Brigadier General
 John Henry Parker (1866–1942), "Gatling Gun Parker"; hero in the Spanish–American War; only U.S. soldier to be awarded the Distinguished Service Cross four times in World War I
 Floyd B. Parks (1911–1942), U.S. Marine aviator who earned the Navy Cross posthumously for his actions leading Marine fighter squadron VMF-221 during the Battle of Midway
John J. Pershing (1860–1948), soldier, General of the Armies; born in Laclede, Missouri
 Sterling Price, Confederate States Army, General of the Missouri State Guard during the Civil War
 William Quantrill (1837–1865), Confederate guerrilla leader (Quantrill's Raiders) in the Civil War
 John H. Quick (1870–1922), U.S. Marine awarded the Medal of Honor in the Spanish–American War, awarded the Distinguished Service Cross and the Navy Cross in World War I
 James E. Rieger (1874–1951), Colonel Mo. National Guard; awarded Distinguished Service Cross and Croix de guerre in World War I
 Roscoe Robinson, U.S. Army General
 Maxwell D. Taylor (1901–1987), U.S. Army General, Chairman of the Joint Chiefs of Staff
 Stephen W. Thompson (1894–1977), first U.S. military pilot to ever shoot down an enemy in aerial combat (1918)
George Allison Whiteman (1919–1941), the first United States Army Air Corps pilot killed in World War II; awarded the Silver Star posthumously for after being shot down in the Japanese attack on Pearl Harbor
 Arthur L. Willard (1870–1935), United States Navy Vice Admiral, winner of Navy Cross, French Legion of Honor, and Belgian Order of Leopold; first man to plant American flag on Cuban soil in the Spanish–American War
William Becknell (1787–1856), soldier, businessman, founder of the Santa Fe Trail
 Johnny Behan (1844–1912), sheriff of Tombstone, Arizona, during the gunfight at the O.K. Corral
 Susan Blow (1843–1916), educator, "the mother of kindergarten"
 Calamity Jane (c. 1852–1903), Indian fighter and frontierswoman
 Dale Carnegie (1888–1955), public and motivational speaker
 Timothy M. Dolan (born 1950), Cardinal of the Roman Catholic Church and Archbishop of New York
 Ella Ewing (1872–1913), "The Missouri Giantess", world's tallest woman (of her era)
 Bobby Greenlease (1947–1953), kidnap-murder victim in case that drew national attention
 Raelynn Hillhouse, national security and intelligence community analyst, Cold War smuggler, spy novelist
 Mary Ranken Jordan (1869–1962), philanthropist and community advocate
 Emmett Kelly (1898–1979), circus clown
 Karlie Kloss (born 1992), model and ballet dancer
 Carrie Nation (1846–1911), advocate for the temperance movement
Rose O'Neill (1874–1944), author, illustrator and creator of the Kewpie doll
 Phyllis Schlafly (born 1924), conservative political activist and author
 Dred Scott, slave and litigant in U.S. Supreme Court Dred Scott Decision
 George Thampy (born 1987), Scripps National Spelling Bee champion 2000, staff member 2006
 Faye Wattleton (born 1943), feminist activist
 Roy Wilkins (1901–1981), civil rights activist
Public office

A–K
Orland K. Armstrong (1893–1987), U.S. Representative, journalist and social activist
 John Ashcroft (born 1942), governor of Missouri (1985–1993), U.S. Senator from Missouri (1995–2001), United States Attorney General (2001–2005)
 Thomas Hart Benton (1782–1858), U.S. Senator
 Richard P. Bland (1835–1899), U.S. Representative for 23 years, Democratic candidate for U.S. President in 1896
 Roy Blunt (born 1950), seven-term U.S. Representative for Missouri's 7th congressional district; House Minority Whip, U.S. Senator
 Christopher S. "Kit" Bond (born 1939), Governor, U.S. Senator of Missouri
 Leonard Boswell (born 1934), U.S. Representative for Iowa's 3rd congressional district
 Bill Bradley (born 1943), U.S. Senator for New Jersey, NBA Hall of Famer; born and reared in Missouri
 Karilyn Brown (born c. 1947), member of the Arkansas House of Representatives for Pulaski County; born in Cape Girardeau
 Clarence Cannon (1879–1964), U.S. Representative 1923–1964, House Appropriations Committee chairman
Albert Sidney Johnson Carnahan (1897–1968), US Representative, US Ambassador to Sierra Leone; father of Governor Mel Carnahan
 Jean Carnahan (born 1933), first Missouri woman to become a U.S. Senator, matriarch of Carnahan political family
 Mel Carnahan (1924–2000), governor, posthumous US Senator (died in plane crash three weeks before he was elected),  patriarch of Carnahan political family
 Robin Carnahan (born 1961), Missouri Secretary of State
 Russ Carnahan (born 1958), US House of Representatives
 Steven Chu (born 1948), U.S. Secretary of Energy
 John Danforth (born 1936), U.S. Senator and United States Ambassador to the United Nations
 Thomas Eagleton (1929–2007), U.S. Senator from Missouri (1968–1987); 1972 Democratic Vice Presidential nominee
 Josh Earnest (born 1977), White House Press Secretary to President Barack Obama
 David R. Francis (1850–1927), U.S. Secretary of the Interior (1896–1897), U.S. Ambassador to Russia (1916–1917)
J. William Fulbright (1905–1995), U.S. Senator, established the Fulbright Fellowships
 Dick Gephardt (born 1941), U.S. Representative from Missouri's 3rd congressional district (1977–2005); Democratic House Majority Leader (1989–1995); candidate for the Democratic nomination for president in the 2004 election
 Michael Gerson (born 1964), chief speechwriter for George W. Bush (2001–2006)
 Ulysses S. Grant, President of the United States (1869–1877)
 Michael Harrington (1928–1989), founder Democratic Socialists of America
 Alphonso Jackson (born 1945), 13th U.S. Secretary of Housing and Urban Development
 James Jones (born 1943), U.S. National Security Advisor under Barack Obama and retired USMC four-star general
Jerry Litton (1937–1976), two-term U.S. Representative; Democratic nominee for U.S. Senate in 1976; killed in plane crash before general election
 Breckinridge Long (1881–1958), U.S. Ambassador to Italy and Assistant United States Secretary of State under President Franklin D. Roosevelt
 Claire McCaskill, State Auditor of Missouri (1999–2007); U.S. Senator (2007–); first woman elected U.S. senator from Missouri
 James Benton Parsons (1911–1993), federal judge
 Clarke Reed (born 1928), Mississippi Republican state chairman, 1966 to 1976; instrumental in the nomination of Gerald R. Ford, Jr. at the 1976 Republican National Convention; reared in Caruthersville, Missouri, and attended the University of Missouri
 Nellie Tayloe Ross (1876–1977), governor of Wyoming (1925–1927); director of the United States Mint (1933–1953); first woman to serve as a state governor
 Jeanne Shaheen (born 1947), U.S. Senator for New Hampshire
Ike Skelton (born 1931), U.S. Congressman for the Missouri 4th District (1977–2011), chairman U.S. House Armed Services Committee
 Stuart Symington, first Air Force Secretary and U.S. Senator from Missouri
 Larry Thompson (born 1945), United States Deputy Attorney General under George W. Bush
 Harry S. Truman (1884–1972), President of the United States
 George Turner (1850–1932), U.S. Senator and international arbitrator
 David King Udall (1851–1938), served in Arizona Legislature, progenitor of the Udall political family
 Harold Volkmer (1931–2011), 20-year member of U.S. House of Representatives for northeast Missouri
 Jim Webb (born 1946), U.S. Senator for Virginia and United States Secretary of the Navy
 Pete Wilson (born 1933), mayor of San Diego, 36th Governor of California, U.S. Senator (1983–1991)
 Robert Coldwell Wood (1923–2005), Secretary of Housing and Urban Development under Lyndon B. Johnson
William F. Baker (born 1953), structural engineer
 Jean Bartik (1924–2011), early computer programmer and designer
 Gordon Bell (born 1934), computer engineer and microcomputer pioneer
 Herbert Blumer (1900–1987), sociologist, developer of symbolic interactionism
 Martin Stanislaus Brennan (1845–1927), scientist and priest
 George Washington Carver (c. 1864–1943), botanist
 Charles Stark Draper (1901–1987), inventor
 David F. Duncan (born 1947), psychologist and epidemiologist
 Meta Given (1888–1981), home economist scientist, dietician, author
 Edward T. Hall (1914–2009), anthropologist and cross-cultural researcher
 Edwin Hubble (1889–1953), astronomer
 Harry Laughlin (1880–1943), eugenicist
 Mark Johnson (born 1949), philosopher
 Virginia Eshelman Johnson (born 1925), psychology researcher
 Jack Kilby (1923–2005), inventor of the integrated circuit
 Pauline Gracia Beery Mack (1891–1974), chemist
 Ernest Manheim (1900–2002), sociologist
 William Howell Masters (1915–2001), gynecologist
Richard Smalley (1943–2005), Nobel Prize-winning chemist, discovered buckminsterfullerene
 Harlow Shapley (1885–1972), astronomer
 William Jasper Spillman (1863–1931), plant geneticist, a founder of agricultural economics
 Lewis Stadler (1896–1954), aka L.J. Stadler, maize geneticist
 Andrew Taylor Still (1828–1917), physician and founder of osteopathic medicine
 Norbert Wiener (1894–1964), mathematician
Related pages

 List of people from Columbia, Missouri
 List of people from Kansas City, Missouri
 List of people from Sedalia, Missouri
 List of people from Springfield, Missouri
 List of people from St. Joseph, Missouri
 List of people from St. Louis

References
This is a list of famous residents of St. Louis or St. Louis County, Missouri. The dates in parentheses signify lifespan, not necessarily dates of actual residence in the city.

A

 Brooke Adams (born 1984), professional wrestler, best known as Brooke Tessmacher
 Akon (born 1973), real name Aliaune Damala Badara Akon Thiam; musician
 Devon Alexander (born 1987), professional boxer, IBF welterweight world champion
 Raleigh DeGeer Amyx (born 1938), collector of Olympic and Presidential memorabilia
 Maya Angelou (1928–2014), poet, playwright, memoirist (I Know Why the Caged Bird Sings)
 Eberhard Anheuser (1805–1880), businessman, owner of company that would become Anheuser-Busch
 Noah Antwiler (born 1980), Internet comedian (The Spoony Experiment)
 Henry Armstrong (1912–1988), professional boxer, welterweight champion 1938–1940
 Dick Ault (1925-2007), track and field athlete

B
Josephine Baker (1906–1975), dancer, singer, actress, Légion d'Honneur appointee, civil rights activist
 Scott Bakula (born 1954), actor (Quantum Leap, Star Trek: Enterprise)
 James F. Ballard (1851–1931), pharmaceutical entrepreneur, and art collector
 Thomas P. Barnett (1870–1929), architect and impressionist painter
 Fontella Bass (1940–2012), soul and R&B singer ("Rescue Me")
 Cool Papa Bell (1903–1991), Negro League baseball player, Hall of Fame member
 Robert Benecke (1835-1903), early photographer
 Graham Bensinger, sports journalist for ESPN Radio
 Sally Benson, author whose short stories became the book, then movie Meet Me in St Louis
 Yogi Berra (born 1925), Major League Baseball player (New York Yankees 1946–1963), manager, coach, Hall of Famer
 Chuck Berry (born 1926), Rock and Roll Hall of Fame musician and composer ("Johnny B. Goode")
 Fred Berry (1951–2003), actor (What's Happening!!)
 Joe Besser (1907–1988), actor, comedian, member of The Three Stooges
Jud Birza (born 1989), model, winner of Survivor: Nicaragua
 Linda Blair (born 1959), actress (The Exorcist)
 Sean Blakemore, actor, Shawn Butler on ABC's General Hospital
 Susan Blow (1843–1916), educator, opened first successful public kindergarten in U.S.
 Kit Bond (born 1939), U.S Senator from Missouri
 Daniel Boone (1734–1820), explorer, hunter, soldier, businessman, politician
 Evan Bourne (born 1983), WWE professional wrestler
 Martin Stanislaus Brennan (1845–1927), Catholic priest and scientist
 Christine Brewer (born 1955), Grammy Award winner, soprano
 Lottie Briscoe (1883-1950), stage and silent film actress
 Lou Brock (born 1939), Major League Baseball player (St. Louis Cardinals 1964–1979), Hall of Famer
 Shirley Brown (born 1947), soul/R&B singer ("Woman to Woman")
 Evan Bourne, real name Matthew Korklan, WWE wrestler
 Butch Buchholz (born 1940), Hall of Fame tennis player
 Jack Buck (1924–2002), Hall of Fame sportscaster, St. Louis Cardinals' announcer 1969–2002
Joe Buck (born 1969), sportscaster, football and baseball announcer for Fox, son of Jack Buck
 Mark Buehrle (born 1979), Major League Baseball pitcher (Chicago White Sox, Toronto Blue Jays)
 Grace Bumbry (born 1937), opera singer
 T-Bone Burnett (born 1948), rock and country performer, composer, and producer
 William S. Burroughs (1914–1997), novelist, social critic, spoken-word performer; grandson of inventor William Seward Burroughs I
 William Seward Burroughs I (1855–1898), inventor of adding machine, founder of Burroughs Corporation; grandfather of novelist William S. Burroughs
 Adolphus Busch (1839–1913), co-founder of Anheuser-Busch with father-in-law Eberhard Anheuser
 Adolphus Busch III (1891–1946), president and CEO of Anheuser-Busch; son of August Anheuser Busch, Sr.
 August Anheuser Busch, Sr. (1865–1934), president and CEO of Anheuser-Busch; son of Adolphus Busch
 Gussie Busch (August Anheuser Busch, Jr.) (1899–1989), president and CEO of Anheuser-Busch, civic leader, philanthropist
August Busch III (born 1937), president and CEO of Anheuser-Busch, civic leader
 August Busch IV (born 1964), president and CEO of Anheuser-Busch, civic leader
 Norbert Leo Butz (born 1967), Tony Award-winning actor
C
 Thomas Cahill (1864–1951), athlete, coach, businessman; a founding father of American soccer
 Kate Capshaw (born 1953), actress (Indiana Jones and the Temple of Doom), wife of Steven Spielberg
 Chip Caray (born 1965), sportscaster for Chicago Cubs, Atlanta Braves and Fox
 Harry Caray (1914–1998), sportscaster, lead announcer for the St. Louis Cardinals (1945–1969) and Chicago Cubs (1981–1997)
 Skip Caray (1939–2008), sportscaster, announcer for the Atlanta Braves (1976–2008)
 Nell Carter (1948–2003), Tony Award-winning singer and actress (Ain't Misbehavin')
 Louis Cella (1866-1918), capitalist, real estate mogul, turfman, and political financier.
 Cedric the Entertainer (born 1964), comedian and actor
 Lori Chalupny (born 1984), U.S. women's national soccer team member
 C. J. Cherryh (born 1942), science-fiction novelist
 Chingy (born 1980), real name Howard Bailey, Jr., rapper and actor
 Kate Chopin (1851–1904), novelist (The Awakening)
Auguste Chouteau (1740–1829), co-founder of St. Louis, urban planner, businessman, civic leader
 David Clarenbach (born 1953), member of Wisconsin State Assembly
 Patrick Clark, television reporter and host
 William Clark (1770–1838), explorer, government administrator
 Sarah Clarke (born 1972), actress (24)
 Mac Cody (born 1972), football player in NFL, CFL, AFL
 Andy Cohen (born 1968), television executive and personality at Bravo network, one of the first openly gay talk-show hosts
 Barry Commoner (born 1917), biologist, college professor, eco-socialist, and presidential candidate
 Arthur Compton (1892–1962), physicist, Nobel Prize in Physics 1927
 Jimmy Connors (born 1952), professional tennis player, 5-time U.S. Open winner in men's singles
 Bert Convy (1933–1991), actor and game-show host
 Carl Ferdinand Cori (1896–1984); Gerty Cori (1896–1957), biochemists, joint Nobel Prize in Physiology or Medicine 1947
 Bob Costas (born 1952), sportscaster, talk-show host
Bryan Cox (born 1968), NFL linebacker 1991–2002
 Jim Cox (born 1920), professional football player
 Lavell Crawford (born 1968), stand-up comedian, actor
 [Kalel Cullen (born 1989), YouTube personality, animal rights activist
D
 John Danforth (born 1936), statesman, diplomat, attorney, civic leader, U.S. Senator 1977–1995
 William H. Danforth (1870–1956), founder of Ralston Purina Company; grandfather of John Danforth and William H. "Bill" Danforth
 William H. "Bill" Danforth (born 1926), physician, professor of medicine, and chancellor of Washington University in St. Louis 1971–1995
 Billy Davis, Jr. (born 1940), R&B and soul singer, member of The 5th Dimension
 Dwight F. Davis (1879–1945), athlete, government administrator
 Miles Davis (1926–1991), musician, winner of Grammy Lifetime Achievement Award
 Dizzy Dean (1910–1974), baseball pitcher, broadcaster
 Dan Dierdorf (born 1949), football player, broadcaster
 Phyllis Diller (1917–2012), comedian
 L. John Doerr (born 1951), venture capitalist
 Domino (born 1972), real name Shawn Antoine Ivy, rapper, born in St. Louis
 Colin Donnell (born 1982), actor, Arrow
 Thom Donovan (born 1974), musician (Lapush)
Jack Dorsey (born 1976), software architect and businessperson, creator of Twitter and Square
 Bob Dotson (born 1946), broadcast journalist, NBC correspondent
 Katherine Dunham (1909–2006), dancer
 Tim Dunigan (born 1955), actor
E
 James Eads (1820–1887), engineer
 Thomas Eagleton (1929–2007), statesman, attorney, civic leader
 Charles Eames (1907–1978), designer, filmmaker
 William Edenborn (1848–1926), industrialist and inventor
 T. S. Eliot (1888–1965), poet (Nobel Prize, Presidential Medal of Freedom), critic
 William Greenleaf Eliot (1811–1887), educator, medical reformer, civil rights activist; grandfather of T. S. Eliot
 Stanley Elkin (1930–1995), author
 Preston Elliot, radio personality, Preston and Steve on WMMR in Philadelphia
 Mary Engelbreit (born 1952), artist
 Walker Evans (1903–1975), photographer
 Steve Ewing, singer/actor, The Urge
F
 Max Factor (1904–1996), cosmetics maker
 Lee Falk (1911–1999), comic strip creator
 Eugene Field (1850–1895), author
 Curtis Finch, Jr. (born 1988), American Idol Season 12 contestant
 Shandi Finnessey (born 1978), Miss USA 2004
 Jenna Fischer (born 1974), actress
 Jamar Fletcher (born 1979), professional football player
 Jason Fletcher (born 1975), sports agent
 Ellen Foley (born 1951), singer, actress
 Richard Fortus (born 1966), musician, Guns N' Roses
 Redd Foxx (1922–1991), comedian, actor
 James Franciscus (1934–1991), actor (Mr. Novak, Longstreet)
 Mary Frann (1943–1998), actress (Newhart)
 Jonathan Franzen (born 1959), author
 David Freese (born 1983), baseball player
G
 Bob Gale (born 1951), screenwriter, film producer
 Alberta Gallatin (1861-1948), stage and screen actress, raised in St. Louis
 Pud Galvin (1856–1902), Major League Baseball player
 Joe Garagiola (born 1926), baseball player, sportscaster, television personality, author
 Jan Garavaglia (born 1956), Chief Medical Examiner of the District 9 Morgue in Orlando, Florida; television personality
 Dave Garroway (1913–1982), television personality, first host of NBC's Today Show
 William H. Gass (born 1924), author, critic
 Taylor Geisse, Octomom
 Martha Gellhorn, author and journalist; third wife of Ernest Hemingway
 Richard Gephardt (born 1941), politician
 Steve Gerber (1947–2008), comic-book writer, co-creator of Howard the Duck
 Frances Ginsberg (1955–2010), opera singer
 David Giuntoli (born 1981), actor
 John Goodman (born 1952), actor
 Harry Goz (1932-2003), actor, Sealab 2021
 Betty Grable (1916–1973), actress
 Ulysses S. Grant (1822–1885), Civil War general and 18th President of the United States
Grant Green (1935–1979), jazz guitarist
 Trent Green, football player
 Dick Gregory (born 1932), comedian, civil rights activist
 Charles Guenther, poet, translator, newspaper critic
 Robert Guillaume (born 1927), Grammy and Emmy Award-winning actor
 James Gunn, screenwriter, director
 Sean Gunn, actor
 Moses Gunn, actor
H
 Laurell K. Hamilton, author
 Jon Hamm (born 1971), Golden Globe award-winning actor, Mad Men
 Henry Hampton (1940–1998), film producer, Eyes on the Prize: America's Civil Rights Years (1954-1965) and Eyes on the Prize II: America at the Racial Crossroads (1965-1980s)
 Sally Hampton (born 1958), writer, producer
 Chuck T. Harmon aka Chuck Harmony, music producer for Mary J. Blige, Celine Dion, Fantasia, Rihanna
 Doris Hart (born 1925), Hall of Fame tennis player, two-time U.S. Open champion
 John Hartford (1937–2001), musician, Grammy Award winner
 Culver Hastedt (1883-1966), runner, gold medal winner at 1904 Summer Olympics
 Donny Hathaway (1945–1979), Grammy-winning singer, songwriter, producer, composer
 Pat Healy, mixed martial arts fighter
 Julius Hemphill (1938–1995), jazz saxophonist, composer
 George E. Hibbard (1924–1991), art collector, advocate for Tibetan Independence
 George Hickenlooper, filmmaker
 Al Hirschfeld (1903–2003), artist and cartoonist
Bobby Hofman (1925-1994) Major League Baseball player
 Solly Hofman (1882-1956), Major League Baseball player
 Robert A. Holekamp (1848–1922), businessman and apiarist
 Ken Holtzman (born 1945), baseball pitcher
 A. E. Hotchner (born 1920), author, editor, philanthropist
 Elston Howard, baseball player, first black player for New York Yankees
 Ryan Howard (born 1979), baseball player, 2005 NL Rookie of the Year, 2006 National League MVP and All-Star first baseman, Philadelphia Phillies
 Huey (1987-2020), real name Lawrence Franks, Jr. , rapper
 Larry Hughes, basketball player, Chicago Bulls
I
 Vedad Ibišević (born 1984), Bosnian soccer player
 William Inge (1913–1973), Pulitzer Prize-winning playwright
 Ernie Isley, songwriter, guitarist of soul and R&B group The Isley Brothers
 Ronald Isley, lead singer of The Isley Brothers; co-owns St. Louis-based Notifi Records
 Halsey Ives (1847–1911), museum and school founder, director of two world-fair art exhibitions (Louisiana Purchase Exposition and World's Columbian Exposition)

J
 Sean James (born 1978), athlete
 Cam Janssen, ice hockey player
 Ella Jenkins, musician
 J-Kwon (born 1986), real name Jerrell Jones, rapper
 Johnnie Johnson (1924–2005), musician
 Justine Joli, adult-film actress
 Scott Joplin, songwriter (Pulitzer Prize), musician, "King of Ragtime"
 Jackie Joyner-Kersee, Olympic gold-medalist track & field athlete; educator; sister of Olympic athlete Al Joyner; sister-in-law of *
K
 Kane (born 1967), real name Glenn Jacobs, professional wrestler
 Stan Kann (1924–2008), musician, entertainer
 Bruce Karsh (born 1955), lawyer and investor
 Ben Kasica (born 1984), musician
 Andreas Katsulas (1946–2006), actor
 David Kaufman (born 1969), character actor and voice actor (Danny Phantom)
 Jim Kekeris (born 1923), NFL player
 Ellie Kemper (born 1980), actress, The Office
 Dorothea Kent (1916–1990), film actress
 Dickie Kerr (1893–1963), baseball pitcher
 Imrat Khan (born 1935), Indian classical musician
 Albert King (1923–1992), musician
 Silver King (1868–1938), Major League Baseball player
 Kevin Kline (born 1947), Academy Award-winning actor
 Karlie Kloss (born 1992), model
L
 Pierre Laclede (1729-1778), urban planner; co-founder of St. Louis; government administrator; civic leader
 Pat LaFontaine (born 1965), NHL hockey player
 Elizabeth Laime, podcaster, writer
 Oliver Lake (born 1942), jazz saxophonist, composer
 Christopher Largen (born 1969), author, filmmaker, journalist, activist
 David Lee (born 1983), NBA basketball player
 Jim Lee (born 1964), comic book artist, writer and publisher
 Murphy Lee, rapper
 Tod Leiweke (born 1960), sports executive
 Maggie LePique (born 1964), jazz radio host
 Stacey Levine, fiction writer, journalist
 Jenifer Lewis (born 1957), actress
 Charles Lindbergh (1902–1974), adventurer, pilot, soldier, author
 Theodore Link (1850–1923), architect
 Sonny Liston (1932–1970), heavyweight champion boxer
M
 Vicki Mabrey (born 1956), broadcast journalist
 Ed Macauley, Hall of Fame basketball player
 Al MacInnis (born 1963), Hall of Fame defenseman and VP of Hockey Operations for (St. Louis Blues)
 Jeremy Maclin (born 1988), football wide receiver (Philadelphia Eagles)
 James S. Marshall, Mayor of Green Bay, Wisconsin
 Peter Martin (born 1970), jazz pianist
 Marsha Mason, Golden Globe Award-winning and Oscar-nominated actress
 Masters and Johnson, medical researchers and therapists, authors
 Stan Masters (1922–2005), American realism artist
 Ron Mathis (1958–1980), Major League baseball player
 Bill Mauldin (1921–2003), cartoonist, Pulitzer Prize winner
 Morton D. May, philanthropist, community leader, art collector, chairman of May Department Stores
 Virginia Mayo, actress
 Emmett McAuliffe, lawyer and talk show host
 Jimmy McCracklin (born 1921), pianist, vocalist and songwriter
 Michael McDonald, singer, Grammy Award winner
 Robert McFerrin, Sr., classical singer; father of Bobby McFerrin
Robert McHenry, encyclopedist and author
 Jim McKelvey (born 1965), computer science engineer, co-founder of Square, a mobile payments company
 Chuck McKinley, Hall of Fame tennis player, 1963 Wimbledon champion
 Ben McLemore (born 1993), basketball player
 George McManus, creator of comic strip Bringing Up Father
 Larissa Meek (born 1978), Miss Missouri Teen USA 1997, Miss Missouri 2001, creative director at BGT Partners
 Javier Mendoza, singer-songwriter and composer
 David Merrick, theatrical producer (Tony Awards)
 Joyce Meyer (born 1943), religious preacher and speaker
 Jay Miller, basketball player
 Russ Mitchell (born 1960), journalist and television news anchor
 Taylor Momsen, singer-songwriter, model, actress
 Archie Moore, boxer, world light-heavyweight champion
 Marianne Moore, poet (Pulitzer Prize), essayist, translator
 Agnes Moorehead, Emmy Award-winning and Oscar-nominated actress
 Bill Mueller, baseball player
 Nick Murphy, NFL punter 2002–2005
N
 Nelly (born 1974), real name Cornell Haynes, Jr., rapper, singer and actor
 Howard Nemerov (1920–1991), poet (Pulitzer Prize, Poet Laureate of the United States), author, critic
 Dustin Nguyen, Vietnamese American actor
 Rich Niemann (born 1946), athlete
 Frank Nuderscher (1880–1959), American Impressionist painter

O
 Dan O'Bannon, screenwriter, director
 Gyo Obata, architect
 St. Louis Jimmy Oden (1903–1977), real name James Burke Oden, blues musician
 Franklin W. Olin (1860–1951), industrialist, philanthropist
 Walter J. Ong, scholar
 Barry Orton, former professional wrestler
 "Cowboy" Bob Orton, former professional wrestler
 Randy Orton, professional wrestler
 Josh Outman, Major League Baseball player, Oakland Athletics
P
 Ken Page (born 1954), actor, voice actor, cabaret singer
 John Pankow (born 1954), actor (Beverly Hills Cop, Mad About You)
 King Parsons (born 1949), professional wrestler
 Ann Peebles (born 1947), soul singer, songwriter
 D.H. Peligro, real name born Darren Henley, drummer for Dead Kennedys and Red Hot Chili Peppers
 Frank P. Pellegrino (1901-1975), businessman, philanthropist, chief executive officer of International Hat Company
 Marlin Perkins (1905–1986), zoologist, Emmy Award-winning broadcaster
 Evan Peters (born 1987), actor (American Horror Story)
 Mike Peters, Pulitzer Prize-winning editorial cartoonist and comic strip artist, creator of Mother Goose and Grimm
 Stone Phillips (born 1954), television journalist
 Julie Piekarski (born 1963), Mouseketeer, actress
 Louise Post (born 1966), musician (Veruca Salt)
 Emil Preetorius (1827–1905), journalist
 Vincent Price (1911–1993), actor (House of Wax, The Ten Commandments, The Fly, Edward Scissorhands)
Victor Proetz (1897–1966), architect, designer, author of poetry and verse
 Chris Pronger (born 1974), hockey player (St. Louis Blues, Philadelphia Flyers)
 Joseph Pulitzer (1847–1911), publisher, philanthropist, creator of the Pulitzer Prize
 Ashley Purdy (born 1984), bassist of Black Veil Brides
R
 Neil Rackers (born 1976), athlete, placekicker for Arizona Cardinals
 Harold Ramis (1944–2014), author, director, actor; graduated from Washington University (1966)
 Judy Rankin (born 1945), professional golfer and TV commentator, World Golf Hall of Famer
 David Rasche (born 1944), actor
 Peter H. Raven (born 1936), botanist, academic administrator, civic leader
 Hank Raymonds (1924–2010), coached Marquette University men's basketball 1977-83; athletic director 1977-87
 Tim Ream, professional soccer player, defender for Bolton Wanderers of Football League Championship and United States men's national soccer team
 Wallace Reid (1891–1923), actor, early cinema sex symbol
 Hadley Richardson (1891–1979), first wife of Ernest Hemingway
 Branch Rickey (1881–1965), baseball executive
 Rob Riti (born 1976), football player
 Doris Roberts (born 1930), actress best known for Everybody Loves Raymond
 Leonard Roberts (born 1972), actor
Lance Robertson, musician and actor best known as host DJ Lance Rock of the children's television show Yo Gabba Gabba! 
 Harry Rogers (born 1950), professional basketball player
 Irma S. Rombauer (1877–1962), author
 William B. Roth (born 1963), actor and producer
 Jean Rouverol (born 1916), author, actress and screenwriter; blacklisted in the 1950s
 Jack Rowe (1856–1911), major league baseball player
 Charles M. Russell (1864–1926), artist and storyteller
S
 John S. Samuel, U.S. Air Force Major General
 David Sanborn, musician, Grammy Award winner
 Edward Saxon, film producer (The Silence of the Lambs)
 Max Scherzer, MLB pitcher
 Phyllis Schlafly, socially conservative Republican author, broadcaster, and political organizer
 Zander Schloss, bassist for the Circle Jerks and The Weirdos; actor
 Red Schoendienst, Hall of Fame second baseman, coach, manager for St. Louis Cardinals
 Chris Schuler, professional soccer player for Real Salt Lake
 Dred Scott (1799–1858) and Harriet Scott (1815–1860), civil rights activists
 Art Shamsky, Major League Baseball outfielder and Israel Baseball League manager
 Mike Shannon (born 1939), affiliated with St. Louis Cardinals for over 50 years, as a player (1962–1970), in front office, and, since 1972, radio and TV announcer
 Henry Shaw (1800–1889), botanist, philanthropist, businessman, author
 William Tecumseh Sherman (1820–1891), soldier; commander of United States Army
 Sherman Silber, physician and infertility specialist
Frank Simek, soccer player with Sheffield Wednesday, also USA International
 Kimora Lee Simmons (born 1975), model and mogul
 Leonard Slatkin, conductor, Grammy Award winner
 Jane Smiley (born 1949), Pulitzer Prize-winning novelist
 Nikko Smith, singer, American Idol contestant; son of Ozzie Smith
 Ozzie Smith, Hall of Fame shortstop for St. Louis Cardinals
 Phyllis Smith, actress on NBC's The Office and Disney's movie Inside Out
 Willie Mae Ford Smith, singer
 Philip Sneed, singer, musician (Story Of The Year, Greek Fire), writer, radio personality
 Corey Spinks, world champion boxer
 Leon Spinks, world champion boxer
 Michael Spinks, world champion boxer
 Paul Stastny, hockey player for St. Louis Blues
 Yan Stastny, hockey player for St. Louis Blues
 Harry Steinfeldt, Major League Baseball player
 Edward Steinhardt (born 1961), poet and author
 Chuck Stone (born 1924) journalist, educator and civil rights activist
Stevie Stone, rapper, born in Columbia, raised in St. Louis, signed to Kansas City-based Strange Music
 Willie Sudhoff, Major League Baseball player
 Roosevelt Sykes (1906-1983), blues musician
 James W. Symington, U.S. Representative, statesman, attorney
 SZA (born 1990), real name Solana Rowe, singer-songwriter, TDE (Top Dawg Entertainment) record label