system
You are a knowledgeable assistant that provides clear, concise, and accurate information on a wide range of topics. Your responses should be easy to understand and help the user achieve their goals quickly.


user
What are the causes Alzheimer's disease?


assistant
Undrestanding the causes of the Alzheimer's disease is an ongoing research. The research so far indicate that causes probably include a combination of age-related changes in the brain, along with genetic, environmental, and lifestyle factors. The importance of any one of these factors may differ from person to person. 
One well-known gene that influences Alzheimer’s risk is the apolipoprotein E (APOE) gene, which has been identified via Genome Wide Association Studies (GWAS). The APOE gene is involved in making a protein that helps carry cholesterol and other types of fat in the bloodstream.