AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 34397615
Drug: Intravenous (IV)
RxNorm normalized name: intravenous (IV) infusion pump
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous (IV) prophylactic antibiotics
Trial: 32224762
Drug: Preventive interventional
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Preventive interventional therapy for brain AVMs
Trial: 32224762
Drug: Preventive treatment
RxNorm normalized name: STANNOUS FLUORIDE 0.004 g in 1 g DENTAL GEL [Enamelon Preventive Treatment]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Preventive treatment for unruptured intracranial aneurysms
Trial: 35804346
Drug: Routine maternal
RxNorm normalized name: undecylenate
DrugBank: Undecylenic acid (DB11117)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Routine maternal and oral health care (Control group, n=200)
Trial: 33141921
Drug: Clopidogrel-based DAPT
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Clopidogrel-based DAPT (600 mg on day 1, 150 mg on days 2-6)
Trial: 33141921
Drug: Clopidogrel single
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Clopidogrel single antiplatelet therapy (SAPT)
Trial: 33183928
Drug: Indocyanine green
RxNorm normalized name: Indocyanine Green
DrugBank: Indocyanine green (DB16024)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Indocyanine green (ICG) fluorescence imaging (FI) with 0.25 mg/kg dosage
Trial: 32198565
Drug: Concurrent percutaneous
RxNorm normalized name: PERCUTANEOUS INTRODUCER SET
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Concurrent percutaneous access during PCNL (group 2)
Trial: 32338624
Drug: Psychopharmacological treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Psychopharmacological treatment and mobile app providing tailored smoking cessation support messages
Trial: 32338624
Drug: Usual care
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Usual care (psychopharmacological treatment)
Trial: 32338624
Drug: Adverse events
RxNorm normalized name: iodine
DrugBank: Iodine (DB05382)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Adverse events related to pharmacological therapy
Trial: 35451359
Drug: Liver meat
RxNorm normalized name: LIVER
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Liver meat balls (LMB) supplement, 3 times a week for 90 days
Trial: 35451359
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group with no supplement
Trial: 32776698
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (conventional treatment and home programmes)
Trial: 38733447
Drug: Beta-blocker use
RxNorm normalized name: Beta Carotene
DrugBank: Beta carotene (DB06755)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Beta-blocker use
Trial: 35411981
Drug: Drug holidays
RxNorm normalized name: ethanol
DrugBank: Ethanol (DB00898)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Drug holidays of more than 11 weeks
Trial: 35411981
Drug: Higher infliximab
RxNorm normalized name: Infliximab
DrugBank: Infliximab (DB00065)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Higher infliximab doses
Trial: 33677827
Drug: Sulodexide (oral
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sulodexide (oral 1,000 LRU/d) for 21 days
Trial: 36424684
Drug: Low-dose indomethacin/levonorgestrel-releasing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-dose indomethacin/levonorgestrel-releasing intrauterine system
Trial: 36424684
Drug: Middle-dose indomethacin/levonorgestrel-releasing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Middle-dose indomethacin/levonorgestrel-releasing intrauterine system
Trial: 36424684
Drug: High-dose indomethacin/levonorgestrel-releasing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose indomethacin/levonorgestrel-releasing intrauterine system
Trial: 36424684
Drug: All treatment
RxNorm normalized name: UNDECYLENIC ACID 8 g in 30 mL / TOLNAFTATE 1 g in 30 mL TOPICAL LIQUID [Fugal nall treatment]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: All treatment groups (including control)
Trial: 32656664
Drug: Caffeine (4
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Caffeine (4 mg/Kg)
Trial: 32711750
Drug: Neonatal hyperglycemia
RxNorm normalized name: Foreskin fibroblast (neonatal)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Neonatal hyperglycemia (blood glucose concentrations ≥153 mg/dL)
Trial: 32517650
Drug: 16 hours
RxNorm normalized name: nicotine
DrugBank: Nicotine (DB00184)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: 16 hours photoperiod with R/B/P/G light quality
Trial: 32517650
Drug: R/B/P/G light
FDA approved: no
EMA approved: no
PMDA approved: no
Description: R/B/P/G light quality
Trial: 33271352
Drug: Palliative Radiation
RxNorm normalized name: allantoin
DrugBank: Allantoin (DB11100)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Palliative Radiation Therapy (PRT36/12)
Trial: 33271352
Drug: Concurrent Chemotherapy
RxNorm normalized name: menthol
DrugBank: Menthol (DB14123)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Concurrent Chemotherapy and Palliative Radiation Therapy (C-PRT40/20)
Trial: 36029105
Drug: 80 µg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 80 µg vaccine
Trial: 36029105
Drug: 120 µg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 120 µg vaccine
Trial: 35105623
Drug: Mifepristone (200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Mifepristone (200 mg orally) followed by misoprostol (800 µg vaginally)
Trial: 35105623
Drug: Letrozole (10
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Letrozole (10 mg orally per day for 3 days) followed by misoprostol (800 µg vaginally on the third day)
Trial: 32707571
Drug: Chemical disorder
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Chemical disorder due to randomized substitution of Cd with Mg
Trial: 37667213
Drug: L-PRF
RxNorm normalized name: L-377202
DrugBank: L-377202 (DB19022)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: L-PRF
Trial: 33154085
Drug: Angiotensin II-stimulating
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Angiotensin II-stimulating antihypertensives
Trial: 33154085
Drug: Angiotensin II-inhibiting
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Angiotensin II-inhibiting antihypertensives
Trial: 33154085
Drug: Both antihypertensive
RxNorm normalized name: Bothrops atrox venom
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Both antihypertensive types
Trial: 32807086
Drug: Non-statin therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Non-statin therapy (placebo)
Trial: 35410935
Drug: Enhanced treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Enhanced treatment as usual provided by their GP
Trial: 33358350
Drug: GTN sublingual
RxNorm normalized name: GTN Sublingual Product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: GTN sublingual powder
Trial: 35847464
Drug: Pharmacist-directed medication
RxNorm normalized name: direct blue 2
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pharmacist-directed medication reconciliation
Trial: 35847464
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (no pharmacist-directed medication reconciliation)
Trial: 34874631
Drug: Cytoreductive surgery
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cytoreductive surgery and platinum-based chemotherapy
Trial: 34298113
Drug: 3D-printed oblong
RxNorm normalized name: CYDONIA OBLONGA LEAF
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3D-printed oblong tablets
Trial: 34298113
Drug: 3D-printed round
RxNorm normalized name: acetaminophen
DrugBank: Acetaminophen (DB00316)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3D-printed round tablets
Trial: 32089783
Drug: Health resort
RxNorm normalized name: Healthy Mama
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Health resort treatment
Trial: 33793743
Drug: OABP+ (Oral
FDA approved: no
EMA approved: no
PMDA approved: no
Description: OABP+ (Oral Antibiotic Prophylaxis with Mechanical Bowel Preparation)
Trial: 33793743
Drug: OABP- (No
FDA approved: no
EMA approved: no
PMDA approved: no
Description: OABP- (No Oral Antibiotic Prophylaxis with Mechanical Bowel Preparation)
Trial: 34949502
Drug: Topical tranexamic
RxNorm normalized name: Tranexamic Acid
DrugBank: Tranexamic acid (DB00302)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Topical tranexamic acid (TA) drops
Trial: 32037862
Drug: Pressure garment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pressure garment application (long glove) for 6 hours/day in addition to 2 hours/week conventional occupational therapy
Trial: 32037862
Drug: Conventional occupational
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional occupational therapy for 2 hours/week
Trial: 36194950
Drug: Cabazitaxel (25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cabazitaxel (25 mg/m2, 6 cycles, three-weekly)
Trial: 36194950
Drug: Paclitaxel (80
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paclitaxel (80 mg/m2, weekly)
Trial: 35551978
Drug: Qirui Weishu
RxNorm normalized name: BENZODODECINIUM BROMIDE 2 g in 500 mL EXTRACORPOREAL LIQUID [Youjie Weishi Antibacterial Hand Wash]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Qirui Weishu capsule
Trial: 35551978
Drug: Sanjiu Weitai
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sanjiu Weitai capsule
Trial: 34380299
Drug: Local magneto-therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Local magneto-therapy
Trial: 34380299
Drug: General magneto-therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: General magneto-therapy
Trial: 35652491
Drug: Restrictive IV
RxNorm normalized name: Pinus spp. wood destructive distillate
DrugBank: Pine tar (DB15840)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Restrictive IV fluid administration (24 hours)
Trial: 35652491
Drug: Restrictive IV
RxNorm normalized name: Pinus spp. wood destructive distillate
DrugBank: Pine tar (DB15840)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Restrictive IV fluid administration
Trial: 35652491
Drug: Restrictive IV
RxNorm normalized name: Pinus spp. wood destructive distillate
DrugBank: Pine tar (DB15840)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Restrictive IV fluid administration and Standard care
Trial: 36066862
Drug: Medication management
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medication management plus combined behavioral intervention (MMCBI)
Trial: 35494290
Drug: Theracurmin at
RxNorm normalized name: rose bengal AT
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Theracurmin at 180 mg per day
Trial: 33433317
Drug: tofacitinib citrate
RxNorm normalized name: Tofacitinib Citrate
DrugBank: Tofacitinib (DB08895)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: tofacitinib citrate test formulation (T)
Trial: 33433317
Drug: tofacitinib citrate
RxNorm normalized name: Tofacitinib Citrate
DrugBank: Tofacitinib (DB08895)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: tofacitinib citrate reference formulation (R)
Trial: 34465695
Drug: Linaclotide 290
RxNorm normalized name: LINACLOTIDE 290MCG CAP
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Linaclotide 290 μg daily for 12 weeks
Trial: 37644897
Drug: THC 10
RxNorm normalized name: THC
DrugBank: Dronabinol (DB00470)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: THC 10 mg
Trial: 32911214
Drug: Control (laboratory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control (laboratory tests and free ART medication)
Trial: 33089368
Drug: Physical therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Physical therapy (transcutaneous electrical nerve stimulation, hot pack, ultrasound treatments, Codman's and range of motion exercises)
Trial: 33089368
Drug: Balneotherapy added
RxNorm normalized name: Stahist AD
DrugBank: Chlorcyclizine (DB08936)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Balneotherapy added to physical therapy
Trial: 32484432
Drug: Carer administration
RxNorm normalized name: caper berry extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Carer administration of as-needed subcutaneous medication (intervention group)
Trial: 32250061
Drug: Subcrestal implant
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Subcrestal implant placement
Trial: 36175107
Drug: Deliberate practice
RxNorm normalized name: menthol
DrugBank: Menthol (DB14123)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Deliberate practice training using role-play and Skillsetter, an online skill-building system with therapy videos, for 15 hours of classroom participation and homework.
Trial: 34280455
Drug: Palonosetron (0.075
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Palonosetron (0.075 mg)
Trial: 35034532
Drug: Optimised regimen
RxNorm normalized name: Anacin Aspirin Regimen Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Optimised regimen (7 × 2 L 2.27% glucose + 5 × 2 L 0.1% glucose over 8 h)
Trial: 35034532
Drug: Standard regimen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard regimen (6 × 2 L 1.36% glucose over 9 h)
Trial: 32542644
Drug: Quadrivalent HPV-vaccine
RxNorm normalized name: HPV, quadrivalent
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Quadrivalent HPV-vaccine
Trial: 36104302
Drug: Vibegron 75
RxNorm normalized name: vibegron 75 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vibegron 75 mg as an intact tablet
Trial: 36104302
Drug: Vibegron 75
RxNorm normalized name: vibegron 75 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vibegron 75 mg crushed and mixed with applesauce
Trial: 36104302
Drug: Vibegron 75
RxNorm normalized name: vibegron 75 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vibegron 75 mg (both intact and crushed)
Trial: 32482616
Drug: Ticagrelor monotherapy
RxNorm normalized name: Ticagrelor
DrugBank: Ticagrelor (DB08816)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Ticagrelor monotherapy after one-month dual antiplatelet therapy (DAPT)
Trial: 33963943
Drug: 0.05% EGCG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.05% EGCG solution + RelyX U200
Trial: 33327746
Drug: Lower HDL
RxNorm normalized name: flowers
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lower HDL cholesterol (1 mmol/L or 39 mg/dL)
Trial: 33327746
Drug: Genetically determined
RxNorm normalized name: Burosumab (genetical recombination)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Genetically determined lower HDL cholesterol (1 mmol/L or 39 mg/dL)
Trial: 34791007
Drug: Camelina oil
RxNorm normalized name: Camelina sativa seed oil
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Camelina oil (1.5 g ALA/d)
Trial: 32706428
Drug: Testosterone Replacement
RxNorm normalized name: Testosterone
DrugBank: (1,2,6,7-3H)Testosterone (DB14093)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Testosterone Replacement Therapy (TRT) for 6 months
Trial: 37965466
Drug: Proton beam
RxNorm normalized name: Beam
DrugBank: Tricyclazole (DB02891)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Proton beam therapy (PBT)
Trial: 34699271
Drug: Transoral surgery
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transoral surgery (TOS) plus 50 Gy postoperative radiation therapy (RT)
Trial: 34699271
Drug: Transoral surgery
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transoral surgery (TOS) plus 60 Gy postoperative radiation therapy (RT)
Trial: 34699271
Drug: Transoral surgery
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transoral surgery (TOS) plus 66 Gy RT and weekly cisplatin
Trial: 34699271
Drug: Functional assessment
RxNorm normalized name: plasma protein fraction Injection [Plasmanate]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Functional assessment of cancer therapy-head and neck
Trial: 33590471
Drug: Levetiracetam (LEV)
RxNorm normalized name: Levetiracetam
DrugBank: Levetiracetam (DB01202)
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: Levetiracetam (LEV) monotherapy
Trial: 36729441
Drug: LipiFlow treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: LipiFlow treatment
Trial: 34349267
Drug: Closed-loop insulin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Closed-loop insulin therapy (using faster insulin aspart)
Trial: 34349267
Drug: Standard insulin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard insulin therapy (control)
Trial: 34349267
Drug: Closed-loop insulin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Closed-loop insulin therapy
Trial: 34508882
Drug: Calcitriol 0.5
RxNorm normalized name: CALCITRIOL 0.5MCG CAP
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Calcitriol 0.5 μg daily for 14 days
Trial: 34930165
Drug: Perioperative chemotherapy
RxNorm normalized name: menthol
DrugBank: Menthol (DB14123)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Perioperative chemotherapy
Trial: 33838357
Drug: Desmopressin (DDAVP)
RxNorm normalized name: desmopressin Injection [DDAVP]
DrugBank: Desmopressin (DB00035)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Desmopressin (DDAVP) at a maximum dose of 0.2 micrograms per kg
Trial: 34971304
Drug: Normal saline
RxNorm normalized name: Normal Saline Flush
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Normal saline (3 mL)
Trial: 33438009
Drug: Low added
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low added sugar intake (0 g/d)
Trial: 33438009
Drug: Medium added
RxNorm normalized name: TRIGLYCERIDES,MEDIUM CHAIN
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medium added sugar intake (75 g/d)
Trial: 33438009
Drug: High added
RxNorm normalized name: high-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High added sugar intake (150 g/d)
Trial: 32360142
Drug: Aminosidine (15
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Aminosidine (15 mg/kg, subcutaneously, once daily, for 28 days) and allopurinol (10 mg/kg, per os, twice daily, for 6 months)
Trial: 32360142
Drug: Meglumine antimoniate
RxNorm normalized name: meglumine antimoniate
DrugBank: Meglumine antimoniate (DB13732)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Meglumine antimoniate (100 mg/kg SC, once daily, for 28 days) and allopurinol (10 mg/kg, per os, twice daily, for 6 months)
Trial: 32360142
Drug: Meglumine antimoniate-allopurinol
RxNorm normalized name: meglumine antimoniate
DrugBank: Meglumine antimoniate (DB13732)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Meglumine antimoniate-allopurinol combination
Trial: 32360142
Drug: Aminosidine-allopurinol combination
RxNorm normalized name: Allopurinol
DrugBank: Allopurinol (DB00437)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Aminosidine-allopurinol combination
Trial: 35242798
Drug: Control formulation
RxNorm normalized name: nut.tx, weight loss-control formulations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control formulation
Trial: 33885035
Drug: EMLA cream
RxNorm normalized name: LIDOCAINE 25 mg in 1 g / PRILOCAINE 25 mg in 1 g TOPICAL CREAM [Emla Cream]
DrugBank: Prilocaine (DB00750)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: EMLA cream (n=75)
Trial: 33885035
Drug: Placebo cream
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo cream (n=77)
Trial: 35147086
Drug: 1000 mg
RxNorm normalized name: bran 1000 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1000 mg Liriope platyphylla extract
Trial: 33946101
Drug: Daily text
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Daily text messages sent via WhatsApp during the study period (group 1)
Trial: 37716952
Drug: atrasentan 0.75
FDA approved: no
EMA approved: no
PMDA approved: no
Description: atrasentan 0.75 mg/day
Trial: 36054166
Drug: Topical methotrexate
RxNorm normalized name: Methotrexate
DrugBank: Methotrexate (DB00563)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Topical methotrexate 1% gel (MTX)
Trial: 36054166
Drug: Topical calcipotriol
RxNorm normalized name: calcipotriol
DrugBank: Calcipotriol (DB02300)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical calcipotriol 0.005% cream (CPL)
Trial: 32938723
Drug: Radical surgery
RxNorm normalized name: Campsis radicans flower extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Radical surgery including pelvic and para-aortic lymphadenectomy and subsequent platinum-based chemotherapy
Trial: 32817407
Drug: PIB with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PIB with saline infusion (group 1, n=23)
Trial: 616191460
Drug: Fentanyl buccal
RxNorm normalized name: Fentanyl Buccal Film
DrugBank: Fentanyl (DB00813)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Fentanyl buccal tablet (FBT) given prophylactically at 20-50% of daily dose
Trial: 33235439
Drug: 5 mg
RxNorm normalized name: talc 25 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg nebivolol plus 20 mg rosuvastatin (NEBI/RSV)
Trial: 33235439
Drug: 5 mg
RxNorm normalized name: talc 25 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg nebivolol (NEBI)
Trial: 33235439
Drug: 20 mg
RxNorm normalized name: urea 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 20 mg rosuvastatin (RSV)
Trial: 32539663
Drug: 2 mg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2 mg/kg weight-based dosing (to a maximum of 200 mg)
Trial: 32539663
Drug: Flat dosing
RxNorm normalized name: ethanol
DrugBank: Ethanol (DB00898)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Flat dosing of 200 mg
Trial: 32539663
Drug: Vial sharing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vial sharing using 100 mg vials
Trial: 34697965
Drug: d-amphetamine (30
FDA approved: no
EMA approved: no
PMDA approved: no
Description: d-amphetamine (30 mg BID) during week 1, switched to placebo during weeks 2-3, placebo during week 4
Trial: 36309966
Drug: Low dose
RxNorm normalized name: Low Dose ASA
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low dose amitriptyline (10–20 mg based on self‐titration)