AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 29777633
Drug: Daily terbutaline
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Daily terbutaline (8 × 0.5 mg) with resistance training
Trial: 29777633
Drug: Daily terbutaline
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Daily terbutaline (8 × 0.5 mg) with endurance training
Trial: 26797412
Drug: HP‐HMB (high‐protein
FDA approved: no
EMA approved: no
PMDA approved: no
Description: HP‐HMB (high‐protein oral nutritional supplement)
Trial: 20667004
Drug: Saline (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Saline (100 μg kg⁻¹)
Trial: 20667004
Drug: Chlorphenamine (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Chlorphenamine (100 μg kg⁻¹)
Trial: 10451784
Drug: Saquinavir-SGC 1200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Saquinavir-SGC 1200 mg administered 3 times daily
Trial: 10451784
Drug: Hard gelatin
RxNorm normalized name: Hard Gelatin Capsule Shell
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hard gelatin capsule (HGC) formulation 600 mg administered 3 times daily
Trial: 8904053
Drug: Intramuscular injection
RxNorm normalized name: rabies, intramuscular injection
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intramuscular injection of pethidine after atropine premedication (pre‐sedated group)
Trial: 55267
Drug: metisoprinol at
RxNorm normalized name: rose bengal AT
FDA approved: no
EMA approved: no
PMDA approved: no
Description: metisoprinol at the dose of 50 mg/kg/day, divided t.i.d., by mouth for 12 days
Trial: 26230903
Drug: Zinc acetate
RxNorm normalized name: Zinc Acetate
DrugBank: Zinc acetate (DB14487)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Zinc acetate alone as first-line therapy (n=9)
Trial: 26230903
Drug: Zinc acetate
RxNorm normalized name: Zinc Acetate
DrugBank: Zinc acetate (DB14487)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Zinc acetate as maintenance therapy after D-penicillamine (n=12)
Trial: 21188849
Drug: Acetaminophen (600
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acetaminophen (600 mg/codeine) (60 mg)
Trial: 18601850
Drug: Gastrodin injection
RxNorm normalized name: Gastrodia elata whole extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Gastrodin injection (1,000 mg administered via intravenous drip infusion for 4 weeks)
Trial: 16525098
Drug: Azithromycin 1,000
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Azithromycin 1,000 mg for three days followed by azithromycin 1,000 mg plus chloroquine 600 mg on days 1 and 2, and azithromycin 1,000 mg plus chloroquine 300 mg on day 3
Trial: 16525098
Drug: Chloroquine 600
RxNorm normalized name: Chloroquine
DrugBank: Chloroquine (DB00608)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Chloroquine 600 mg on days 1 and 2, then 300 mg on day 3
Trial: 12641516
Drug: Thalidomide, 200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Thalidomide, 200 mg daily for 2 weeks
Trial: 28609128
Drug: Micronized progesterone
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Micronized progesterone (utrogestran®) at 100 mg
Trial: 21810018
Drug: Intravitreal injection
RxNorm normalized name: Eylea 2 MG per 0.05 ML Intravitreal Injection
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravitreal injection of bevacizumab (1.25 mg)
Trial: 16689808
Drug: 5% sodium
RxNorm normalized name: Dextrose 5% and 0.45% Sodium Chloride
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5% sodium lauryl sulfate solution
Trial: 16689808
Drug: 10% sodium
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 10% sodium lauryl sulfate solution
Trial: 9290025
Drug: Extrarenal alterations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Extrarenal alterations induced by ARF treatment.
Trial: 29315164
Drug: Strength Training
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Strength Training Group (STG) - 10 weeks of strength training including plyometric, sprint, and resistance training, performed twice weekly in addition to normal running.
Trial: 27555187
Drug: Caudal epidural
RxNorm normalized name: epidermal growth factor
DrugBank: Nepidermin (DB14145)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Caudal epidural block (CEB, 0.75 mL/kg of 0.25% bupivacaine)
Trial: 24722560
Drug: Saccharomyces boulardii
RxNorm normalized name: Saccharomyces boulardii
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Saccharomyces boulardii 750 mg/day for 6 weeks
Trial: 22251037
Drug: Interim Restorative
RxNorm normalized name: DRESSING,RESTORE
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Interim Restorative Treatment (IRT) using FUJI IX
Trial: 11484954
Drug: Docetaxel (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Docetaxel (100 mg/m2) + Mitoxantrone (20 mg/m2) + G-CSF (150 mcg/m2/d s.c.)
Trial: 28237506
Drug: Antidepressant medication
RxNorm normalized name: ANTIDEPRESSANTS
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Antidepressant medication (specific medications not detailed)
Trial: 11700398
Drug: Isonitrogenous control
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Isonitrogenous control amino acid solution
Trial: 9578795
Drug: Conventional eye
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional eye patches
Trial: 3499182
Drug: Dalargin (1-4
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dalargin (1-4 mg)
Trial: 7348120
Drug: Nalorphine (5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nalorphine (5 mg)
Trial: 21274983
Drug: Placebo (NaCl
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (NaCl solution)
Trial: 18030228
Drug: Esomeprazole 20
RxNorm normalized name: esomeprazole 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Esomeprazole 20 mg once daily for 8 weeks
Trial: 26078574
Drug: Esomeprazole 20
RxNorm normalized name: esomeprazole 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Esomeprazole 20 mg once daily for 2 weeks
Trial: 3077320
Drug: Cognitive-behavioral group
RxNorm normalized name: Streptococcus viridans group
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cognitive-behavioral group therapy (stress inoculation training)
Trial: 30502505
Drug: Lusutrombopag (3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lusutrombopag (3 mg once daily for up to 7 days)
Trial: 26453483
Drug: Low-protein diet
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-protein diet (LPD) 0.8 g/kg/day
Trial: 19562716
Drug: Oral branched-chain
RxNorm normalized name: Machilus thunbergii branch extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral branched-chain amino acids (BCAAs) 12.45 g/day for at least 1 year
Trial: 2676391
Drug: Conventional therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional therapy including positive end-expiratory pressure (PEEP)
Trial: 26048096
Drug: Dacomitinib 30
RxNorm normalized name: dacomitinib 30 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dacomitinib 30 mg
Trial: 21985413
Drug: 135 mg
RxNorm normalized name: cocaine 135 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 135 mg minocycline tablet formulation
Trial: 19282143
Drug: Combination therapy
RxNorm normalized name: REGN10933+REGN10987 combination therapy
DrugBank: Anti-SARS-CoV-2 REGN-COV2 (DB15691)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination therapy (sulfasalazine, methotrexate, prednisolone)
Trial: 19282143
Drug: Monotherapy (sulfasalazine)
RxNorm normalized name: Adoptive immunotherapy agent CTL019
DrugBank: Tisagenlecleucel (DB13881)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Monotherapy (sulfasalazine)
Trial: 15001600
Drug: Oral glutamine
RxNorm normalized name: Glutamine
DrugBank: L-Glutamine (DB00130)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Oral glutamine (0.7 g/kg.d)
Trial: 15001600
Drug: Recombinant human
RxNorm normalized name: Recombinant human TNF
DrugBank: Etanercept (DB00005)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Recombinant human growth hormone (rhGH) (0.3 mg/kg.wk)
Trial: 12042546
Drug: Surfaxin lavage
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Surfaxin lavage (8 mL/kg dilute Surfaxin 2.5 mg/mL, instilled into each lung, repeated twice, final lavage with 10 mg/mL)
Trial: 30232735
Drug: Oral ketamine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral ketamine
Trial: 2110937
Drug: Guar gum
RxNorm normalized name: Guar Gum
DrugBank: Guar gum (DB13446)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Guar gum (5 g t.i.d. with meals)
Trial: 29098875
Drug: Saline and
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Saline and placebo tablets (control group)
Trial: 23609341
Drug: Sequential (exercise
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sequential (exercise first)
Trial: 14676740
Drug: 0.625 mg/day
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.625 mg/day conjugated equine estrogen only
Trial: 14676740
Drug: Estrogen plus
RxNorm normalized name: estrogens
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Estrogen plus 2.5 mg/day medroxyprogesterone acetate
Trial: 10731503
Drug: Iron and
RxNorm normalized name: beef,iron and wine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Iron and folic acid supplements with zinc (15 mg Zn)
Trial: 3890398
Drug: Hepatitis B
RxNorm normalized name: HEPATITIS B
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hepatitis B vaccine (20 micrograms dose)
Trial: 31932389
Drug: Topical Dynamiclear
RxNorm normalized name: Dynamiclear Oro Topical Product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical Dynamiclear
Trial: 28873333
Drug: Echocardiography-guided therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Echocardiography-guided therapy
Trial: 24816691
Drug: Palatal implant
RxNorm normalized name: malate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Palatal implant surgery
Trial: 16207152
Drug: rostafuroxin 0.15
FDA approved: no
EMA approved: no
PMDA approved: no
Description: rostafuroxin 0.15 mg/day
Trial: 16207152
Drug: rostafuroxin 0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: rostafuroxin 0.5 mg/day
Trial: 16207152
Drug: rostafuroxin 1.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: rostafuroxin 1.5 mg/day
Trial: 16207152
Drug: rostafuroxin 5.0
FDA approved: no
EMA approved: no
PMDA approved: no
Description: rostafuroxin 5.0 mg/day
Trial: 16207152
Drug: rostafuroxin (all
FDA approved: no
EMA approved: no
PMDA approved: no
Description: rostafuroxin (all doses)
Trial: 1820641
Drug: Daily artesunate
RxNorm normalized name: Artesunate
DrugBank: Artesunate (DB09274)
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: Daily artesunate regimen (200 mg initial dose followed by 100 mg daily for 4 days)
Trial: 1820641
Drug: Twice daily
RxNorm normalized name: CAPSULE, TWICE DAILY
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Twice daily artesunate regimen (100 mg 12 hourly for 2 doses on the first day, followed by 50 mg 12 hourly for another 8 doses)
Trial: 319116
Drug: Indoprofen (800
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Indoprofen (800 mg/day)
Trial: 21969851
Drug: UC781 gel
FDA approved: no
EMA approved: no
PMDA approved: no
Description: UC781 gel 0.25%
Trial: 21969851
Drug: UC781 gel
FDA approved: no
EMA approved: no
PMDA approved: no
Description: UC781 gel 0.1%
Trial: 11432470
Drug: Standard uncoated
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard uncoated ECC with systemic heparin 400 IE/kg
Trial: 9928752
Drug: Nitrendipine 20
RxNorm normalized name: nitrendipine 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nitrendipine 20 mg
Trial: 2557274
Drug: Nedocromil sodium
RxNorm normalized name: Nedocromil Sodium
DrugBank: Nedocromil (DB00716)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Nedocromil sodium (2 puffs of 2 mg each twice daily)
Trial: 2557274
Drug: Placebo (2
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (2 puffs twice daily)
Trial: 27278517
Drug: Moderate catheter
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Moderate catheter stability VisiTag setting (3-mm distance limit for at least 5 s, minimum contact force of 8 g over 25% of the set time period, target FTI ≥300 g*s)
Trial: 27278517
Drug: Strict catheter
RxNorm normalized name: Euphrasia stricta extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Strict catheter stability VisiTag setting (3-mm distance limit for at least 10 s, minimum contact force of 10 g over 50% of the set time period, target FTI ≥400 g*s)
Trial: 11478144
Drug: Concurrent use
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Concurrent use of ondansetron and dexamethasone (DEX group)
Trial: 3301606
Drug: Cisapride, 10
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cisapride, 10 mg three times daily, orally, before meals
Trial: 2806497
Drug: Inhalation of
RxNorm normalized name: Ocean brand of sodium chloride Inhalant Product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhalation of cold dry air for 4 minutes
Trial: 30686542
Drug: Citrate Dialysis
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Citrate Dialysis Fluid (CDF) with 1mmol/L of citrate
Trial: 30686542
Drug: Acetate Dialysis
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acetate Dialysis Fluid (ADF) with 3mmol/L of acetate
Trial: 16249508
Drug: Inhaled carbon
RxNorm normalized name: carbon dioxide Inhalant Product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhaled carbon monoxide (500 ppm)
Trial: 1693732
Drug: Felodipine ER
RxNorm normalized name: Felodipine ER
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Felodipine ER 5 mg
Trial: 7933821
Drug: Human atrial
RxNorm normalized name: Insulin Human
DrugBank: Insulin human (DB00030)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Human atrial natriuretic peptide (ANP) at 0.20 micrograms/kg/min i.v. for 24 hours or 0.08 micrograms/kg/min i.a. for 8 hours, with furosemide or mannitol or no diuretic.
Trial: 7933821
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (Group II) treated with diuretics or no diuretic, without ANP.
Trial: 31140342
Drug: Second generation
RxNorm normalized name: Second generation cephalosporin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Second generation antipsychotics in patients with substance use
Trial: 31140342
Drug: Second generation
RxNorm normalized name: Second generation cephalosporin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Second generation antipsychotics in patients without substance use
Trial: 26160525
Drug: Melatonin 3
RxNorm normalized name: melatonin 3 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Melatonin 3 mg t.i.d. for 1 month
Trial: 23307258
Drug: FLOT regimen
RxNorm normalized name: Anacin Aspirin Regimen Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: FLOT regimen (oxaliplatin 85 mg/m², docetaxel 50 mg/m², leucovorin 200 mg/m², 5-FU 1200 mg/m²) administered biweekly
Trial: 21217084
Drug: Cisplatin 50
RxNorm normalized name: cisplatin 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cisplatin 50 mg/m(2) weekly × nine cycles
Trial: 21217084
Drug: Cisplatin 75
RxNorm normalized name: Cisplatin
DrugBank: Cisplatin (DB00515)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Cisplatin 75 mg/m(2) every 21 days × six cycles (Control)
Trial: 22959217
Drug: Ginkgo biloba
RxNorm normalized name: Ginkgo Biloba
DrugBank: Ginkgo biloba (DB01381)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ginkgo biloba extract (EGb761) 120 mg twice per day
Trial: 20534062
Drug: Conventional nutritional
RxNorm normalized name: Ocean Blue Nutritionals Omega-3 1450 Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional nutritional rehabilitation therapy
Trial: 18198649
Drug: Retention enema
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Retention enema with combination of Chinese and Western drugs
Trial: 18198649
Drug: Western drugs
RxNorm normalized name: Western wheatgrass
DrugBank: Pascopyrum smithii pollen (DB10719)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Western drugs alone
Trial: 11881888
Drug: Ibuprofen (5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ibuprofen (5 mg kg(‐1))
Trial: 2676430
Drug: Intranasal glucagon
RxNorm normalized name: Glucagon
DrugBank: Glucagon (DB00040)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Intranasal glucagon
Trial: 12357302
Drug: Oral vinorelbine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral vinorelbine (80 mg/m²) administered after fasting
Trial: 12357302
Drug: Oral vinorelbine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral vinorelbine (80 mg/m²) administered after ingestion of a standard continental breakfast
Trial: 12357302
Drug: Oral vinorelbine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral vinorelbine (80 mg/m²) in both feeding conditions
Trial: 10550358
Drug: Dithranol +
RxNorm normalized name: Zithranol
DrugBank: Anthralin (DB11157)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dithranol + Tazarotene (combined therapy)
Trial: 10550358
Drug: Dithranol (monotherapy)
RxNorm normalized name: Zithranol
DrugBank: Anthralin (DB11157)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Dithranol (monotherapy)
Trial: 7750526
Drug: BCG, 81
FDA approved: no
EMA approved: no
PMDA approved: no
Description: BCG, 81 mg
Trial: 7750526
Drug: BCG, 27
FDA approved: no
EMA approved: no
PMDA approved: no
Description: BCG, 27 mg
Trial: 6370283
Drug: Metoprolol (single
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metoprolol (single dose)
Trial: 6712861
Drug: Propranolol (chronic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Propranolol (chronic treatment for 28 days)
Trial: 6712861
Drug: Metoprolol (chronic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metoprolol (chronic treatment for 28 days)
Trial: 31309919
Drug: Vitamin D
RxNorm normalized name: Vitamin D
DrugBank: Vitamin D (DB11094)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin D (50,000 IU every 2 weeks) + n-3 fatty acids (2× 1000 mg/d from flaxseed oil)
Trial: 24951467
Drug: CloB2A2 regimen
RxNorm normalized name: Anacin Aspirin Regimen Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: CloB2A2 regimen (clofarabine 30 mg/m(2)/day for 4 days, busulfan 3.2 mg/kg/day for 2 days, antithymocyte globulin 2.5 mg/kg/day for 2 days)
Trial: 15472771
Drug: Conventional analgesic
RxNorm normalized name: Analgesic Balm GRX
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional analgesic measures (Control)
Trial: 2156887
Drug: Finasteride 25
RxNorm normalized name: Finasteride
DrugBank: Finasteride (DB01216)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Finasteride 25 mg
Trial: 15319158
Drug: Finasteride 0.2
RxNorm normalized name: MINOXIDIL 5 g in 100 g / FINASTERIDE 0.25 g in 100 g TOPICAL AEROSOL, FOAM [JOHNSON FOAM PRO]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Finasteride 0.2 mg
Trial: 28803386
Drug: Tamsulosin 0.4
RxNorm normalized name: tamsulosin 0.4 mg oral capsule
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tamsulosin 0.4 mg/day (n=60)
Trial: 28803386
Drug: Standard medical
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard medical therapy alone (n=64)
Trial: 21842454
Drug: No orthopedic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No orthopedic treatment (control group)
Trial: 17555465
Drug: Sirolimus (n
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sirolimus (n = 30; dosed to maintain trough concentrations of 10‐25 ng ml(‐1) until week 8, and then 8‐15 ng ml(‐1) thereafter) in combination with daclizumab, oral MMF and corticosteroids
Trial: 17555465
Drug: Ciclosporin (CsA)
RxNorm normalized name: ciclosporin
DrugBank: Cyclosporine (DB00091)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Ciclosporin (CsA) (n = 15; administered as per centre practice) in combination with daclizumab, oral MMF and corticosteroids
Trial: 15104606
Drug: 100 microg
RxNorm normalized name: Digoxin 100 microgram oral capsule
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 microg of oral misoprostol
Trial: 9010987
Drug: Granisetron (combined
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Granisetron (combined doses)
Trial: 7944533
Drug: Continuous oral
RxNorm normalized name: Ivy Dry Super Continuous Spray
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Continuous oral flucloxacillin
Trial: 7944533
Drug: Antibiotics when
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Antibiotics when clinically indicated
Trial: 289417
Drug: Prophylactic metronidazole
RxNorm normalized name: Metronidazole
DrugBank: Metronidazole (DB00916)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Prophylactic metronidazole (Flagyl) 200 mg every 8 hours for 3 days
Trial: 23808185
Drug: Combined therapy
RxNorm normalized name: REGN10933+REGN10987 combination therapy
DrugBank: Anti-SARS-CoV-2 REGN-COV2 (DB15691)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combined therapy of mexidol 300 mg and picamilon 150 mg
Trial: 19442782
Drug: 600 mcg
RxNorm normalized name: Biotin 600 MCG Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 600 mcg oral misoprostol
Trial: 23697561
Drug: 400 mcg
RxNorm normalized name: Biotin 400 MCG Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 400 mcg sublingual misoprostol
Trial: 17141985
Drug: New amoxicillin/clavulanate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: New amoxicillin/clavulanate therapeutic system (1500 mg amoxicillin and 125 mg clavulanic acid)
Trial: 14732656
Drug: Verteporfin PDT
RxNorm normalized name: Verteporfin
DrugBank: Verteporfin (DB00460)
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: Verteporfin PDT with 14 mg/m² infusion followed by red light exposure at 180 J/cm²
Trial: 11558864
Drug: Ceftriaxone 2
RxNorm normalized name: ceftriaxone 250 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ceftriaxone 2 g
Trial: 11558864
Drug: Ampicillin/sulbactam 3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ampicillin/sulbactam 3 g
Trial: 9577289
Drug: Ranitidine treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ranitidine treatment
Trial: 31897548
Drug: Low-dose (3-7
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-dose (3-7 spheroids/cm2)
Trial: 31897548
Drug: Medium-dose (10-30
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medium-dose (10-30 spheroids/cm2)
Trial: 31897548
Drug: High-dose (40-70
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose (40-70 spheroids/cm2)