AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 8204277
Drug: Sucralfate cream
RxNorm normalized name: Sucralfate
DrugBank: Sucralfate (DB00364)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Sucralfate cream
Trial: 15542162
Drug: No cream
RxNorm normalized name: Oil, Multi Ingredient Topical application Oil [AVEENO CREAMY MOISTURIZING OIL]
DrugBank: Nitric Oxide (DB00435)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: No cream (control)
Trial: 11380297
Drug: hCG on
FDA approved: no
EMA approved: no
PMDA approved: no
Description: hCG on the day of embryo transfer + daily vaginal progesterone (group II)
Trial: 11380297
Drug: hCG in
FDA approved: no
EMA approved: no
PMDA approved: no
Description: hCG in combination with daily vaginal progesterone (group IV)
Trial: 11380297
Drug: hCG only
FDA approved: no
EMA approved: no
PMDA approved: no
Description: hCG only or additional injection of hCG
Trial: 9233866
Drug: Radiotherapy plus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Radiotherapy plus goserelin (3.6 mg subcutaneously every four weeks for three years)
Trial: 7654898
Drug: Pravastatin (20-40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pravastatin (20-40 mg) with hypolipemiant dietetic treatment
Trial: 7654898
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (dietetic treatment only)
Trial: 26945818
Drug: Ropivacaine 40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ropivacaine 40 ml
Trial: 21087499
Drug: Propranolol added
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Propranolol added to standard treatment
Trial: 14501856
Drug: Intraoperative Thymoglobulin
RxNorm normalized name: Thymoglobulin
DrugBank: Antithymocyte immunoglobulin (rabbit) (DB00098)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intraoperative Thymoglobulin (1 mg/kg/dose, 3 to 6 doses during the first week posttransplant)
Trial: 14501856
Drug: Postoperative Thymoglobulin
RxNorm normalized name: Thymoglobulin
DrugBank: Antithymocyte immunoglobulin (rabbit) (DB00098)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Postoperative Thymoglobulin (1 mg/kg/dose, 3 to 6 doses during the first week posttransplant)
Trial: 10434160
Drug: Venlafaxine (200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Venlafaxine (200 to 300 mg/day)
Trial: 10434160
Drug: Paroxetine (30
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paroxetine (30 to 40 mg/day)
Trial: 8794438
Drug: E3 (0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: E3 (0.5 mg every other day) + Ca (0.5 g/day)
Trial: 9212355
Drug: Low Molecular
RxNorm normalized name: Low molecular weight heparin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low Molecular Weight Heparin (LMWH)
Trial: 6352626
Drug: Ceftazidime 2
RxNorm normalized name: ceftazidime 2000 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ceftazidime 2 g iv dose
Trial: 26037521
Drug: Vitamin D3
RxNorm normalized name: Vitamin D3
DrugBank: Cholecalciferol (DB00169)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin D3 supplementation (20 μg/d)
Trial: 24675102
Drug: Parenteral corticosteroid
RxNorm normalized name: abiraterone and corticosteroids
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Parenteral corticosteroid (PS) (n=33)
Trial: 24675102
Drug: 4 mg
RxNorm normalized name: lutein 4 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 4 mg nebulized steroid (NB) (n=27)
Trial: 24675102
Drug: 8 mg
RxNorm normalized name: alloin 8 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 8 mg nebulized steroid (NB) (n=26)
Trial: 17919549
Drug: Goserelin acetate
RxNorm normalized name: Goserelin Acetate
DrugBank: Goserelin (DB00014)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Goserelin acetate 10.8 mg plus iron (ferrous sulfate 325 mg TID)
Trial: 17919549
Drug: Sham (iron
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sham (iron monotherapy)
Trial: 12074599
Drug: Vitamin C
RxNorm normalized name: Vitamin C
DrugBank: Sodium ascorbate (DB14482)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin C supplementation (250 mg/day for six weeks)
Trial: 10335420
Drug: Propranolol (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Propranolol (20 mg for weeks 1 and 2, 30 mg for weeks 3 and 4, twice daily)
Trial: 6749996
Drug: EB-FITC combination
RxNorm normalized name: Folate-FITC
DrugBank: EC-17 (DB12559)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: EB-FITC combination
Trial: 6749996
Drug: PI-FITC combination
RxNorm normalized name: PI-103
DrugBank: PI-103 (DB17046)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PI-FITC combination
Trial: 6749996
Drug: DAPI-TRITC combination
RxNorm normalized name: combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: DAPI-TRITC combination
Trial: 29986268
Drug: Pill counts
RxNorm normalized name: oteseconazole
DrugBank: Oteseconazole (DB13055)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Pill counts (self-reported adherence)
Trial: 28427456
Drug: Surgery with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Surgery with atrial natriuretic peptide (ANP) administration for 3 days during the perioperative period
Trial: 24125415
Drug: Beetroot juice
RxNorm normalized name: tamarind juice
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Beetroot juice (140 mL providing approximately 500 mg dietary nitrate)
Trial: 14613435
Drug: Inhaled corticosteroids
RxNorm normalized name: CORTICOSTEROIDS
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhaled corticosteroids (ICSs) as maintenance treatment for persistent asthma
Trial: 14613435
Drug: Addition of
RxNorm normalized name: OIL OF CAMPHOR
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Addition of a long-acting inhaled beta2-agonist or a leukotriene modifier to ICS therapy
Trial: 27719743
Drug: 400 mg
RxNorm normalized name: mesna 400 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 400 mg LCZ696 after low-fat meal
Trial: 27719743
Drug: 400 mg
RxNorm normalized name: mesna 400 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 400 mg LCZ696 after high-fat meal
Trial: 27719743
Drug: 400 mg
RxNorm normalized name: mesna 400 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 400 mg LCZ696 under fasting condition
Trial: 24978674
Drug: Testosterone treatment
RxNorm normalized name: Testosterone
DrugBank: (1,2,6,7-3H)Testosterone (DB14093)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Testosterone treatment (im testosterone undecanoate) for 40 weeks
Trial: 23484301
Drug: No treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No treatment (direct restoration)
Trial: 18259825
Drug: Neoadjuvant therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Neoadjuvant therapy for pancreatic cancer
Trial: 18259825
Drug: Adjuvant therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Adjuvant therapy for pancreatic cancer
Trial: 10959482
Drug: Lamivudine (100-150
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lamivudine (100-150 mg daily)
Trial: 2861759
Drug: Pancuronium (80
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pancuronium (80 micrograms/kg iv) in patients pretreated with beta-receptor blockers and receiving fentanyl (7 micrograms/kg)
Trial: 2861759
Drug: Pancuronium (80
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pancuronium (80 micrograms/kg iv) in patients not on preoperative beta-receptor blocker medication
Trial: 31851172
Drug: Cortexin (10
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cortexin (10 days, once daily intramuscularly)
Trial: 23739513
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (no pharmacotherapy)
Trial: 25026806
Drug: Adaptol (3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Adaptol (3 tablets, 1500 mg daily)
Trial: 25026806
Drug: Standard treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard treatment (disintoxication therapy, prednisolone 30‐60 mg/day, antihistamines, phototherapy, topical steroids, topical emollients)
Trial: 22494062
Drug: I-gel(TM) laryngeal
RxNorm normalized name: iobenguane I-131
FDA approved: no
EMA approved: no
PMDA approved: no
Description: I-gel(TM) laryngeal mask airway with sevoflurane
Trial: 22494062
Drug: I-gel(TM) laryngeal
RxNorm normalized name: iobenguane I-131
FDA approved: no
EMA approved: no
PMDA approved: no
Description: I-gel(TM) laryngeal mask airway with desflurane
Trial: 21038653
Drug: BAI with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: BAI with oleum fructus bruceae (OFB) + chemotherapeutic agents (CTA)
Trial: 21038653
Drug: BAI with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: BAI with chemotherapeutic agents (CTA) alone
Trial: 16398771
Drug: Rectal misoprostol
RxNorm normalized name: Misoprostol
DrugBank: Misoprostol (DB00929)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Rectal misoprostol (400 microg) and intravenous oxytocin (10 IU/hour)
Trial: 8794822
Drug: Losartan (50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Losartan (50 mg QD)
Trial: 8794822
Drug: Metoprolol (95
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metoprolol (95 mg QD)
Trial: 6391153
Drug: 200 mg
RxNorm normalized name: RNA 200 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 200 mg SAMe per os tid during oral contraceptive treatment
Trial: 6391153
Drug: Oral contraceptives
RxNorm normalized name: VCF Contraceptive
DrugBank: Nonoxynol-9 (DB06804)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral contraceptives containing 50 micrograms ethynylestradiol plus 250 micrograms d-norgestrel
Trial: 29354952
Drug: Autologous blood
RxNorm normalized name: Banked autologous blood
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Autologous blood injection at Zusanli (ST 36)
Trial: 21570271
Drug: 9 g
RxNorm normalized name: Publix Pen Needle 29 g
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 9 g brewer's yeast (42 μg Cr) daily for 3 months
Trial: 10856732
Drug: eprosartan (540+/‐96
FDA approved: no
EMA approved: no
PMDA approved: no
Description: eprosartan (540+/‐96 mg/day)
Trial: 8985221
Drug: Polysaccharide vaccine
RxNorm normalized name: Typhoid Vi polysaccharide vaccine
DrugBank: Typhoid Vi polysaccharide vaccine (DB10803)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Polysaccharide vaccine
Trial: 1588148
Drug: PRP-D vaccine
RxNorm normalized name: Hib (PRP-D)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PRP-D vaccine (polysaccharide conjugated to diphtheria toxoid)
Trial: 1588148
Drug: HbOC vaccine
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: HbOC vaccine (oligosaccharide conjugated to CRM197 protein)
Trial: 29027352
Drug: Donor dopamine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Donor dopamine treatment
Trial: 24737923
Drug: Anti-inflammatory therapy
RxNorm normalized name: Surpass Anti-Inflammatory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Anti-inflammatory therapy after surgery
Trial: 24737923
Drug: No anti-inflammatory
RxNorm normalized name: Surpass Anti-Inflammatory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No anti-inflammatory therapy after surgery
Trial: 24417929
Drug: Aspirin group
RxNorm normalized name: Aspirin
DrugBank: Acetylsalicylic acid (DB00945)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Aspirin group (continued aspirin, discontinued clopidogrel at least 5 days before surgery)
Trial: 24417929
Drug: Aspirin and
RxNorm normalized name: Aspirin and Caffeine Tablets
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Aspirin and clopidogrel group (had both until 3 days before surgery)
Trial: 24417929
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (discontinued antiplatelet therapy 5 days before surgery)
Trial: 18179713
Drug: Olanzapine (5-20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Olanzapine (5-20 mg/day) for bipolar mania
Trial: 18179713
Drug: Olanzapine (10-20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Olanzapine (10-20 mg/day) for schizophrenia
Trial: 16794788
Drug: Carvedilol (5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Carvedilol (5 mg twice per day, increased to maximum tolerated dose)
Trial: 16794788
Drug: Metoprolol tartrate
RxNorm normalized name: Metoprolol Tartrate
DrugBank: Metoprolol (DB00264)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Metoprolol tartrate (20 mg three times per day, increased to maximum tolerated dose)
Trial: 12084605
Drug: Omapatrilat 40
RxNorm normalized name: OMAPATRILAT
DrugBank: Omapatrilat (DB00886)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Omapatrilat 40 mg
Trial: 12084605
Drug: Omapatrilat 20
RxNorm normalized name: OMAPATRILAT
DrugBank: Omapatrilat (DB00886)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Omapatrilat 20 mg
Trial: 10637684
Drug: Pharmacological treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pharmacological treatment (methylphenidate or placebo)
Trial: 10637684
Drug: Nonpharmacological treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nonpharmacological treatment (parent groups: training or support)
Trial: 1975189
Drug: Esmolol (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Esmolol (100 mg and 200 mg)
Trial: 7270984
Drug: Albuterol syrup
RxNorm normalized name: Albuterol
DrugBank: Albuterol (DB01001)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Albuterol syrup
Trial: 24608079
Drug: Higher dose
RxNorm normalized name: BENZOCAINE 50 mg in 1 mL TOPICAL GEL [HIGHER CONTROL Male Climax Control Lubricating]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Higher dose intravenous methotrexate (MTX) 2.5 g/m
Trial: 24608079
Drug: Standard dose
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard dose intravenous methotrexate (MTX) 1 g/m
Trial: 24608079
Drug: High-dose cytosine
RxNorm normalized name: cytosine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose cytosine arabinoside/asparaginase
Trial: 23012385
Drug: 500 mg
RxNorm normalized name: bran 500 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 500 mg intravenous doripenem
Trial: 23012385
Drug: 1000 mg
RxNorm normalized name: bran 1000 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1000 mg intravenous doripenem
Trial: 20212271
Drug: Perindopril-based blood
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Perindopril-based blood pressure-lowering therapy
Trial: 15141263
Drug: Acetaminophen 650
RxNorm normalized name: acetaminophen 650 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acetaminophen 650 mg per rectum every 4 hours
Trial: 12667363
Drug: Calcium carbonate
RxNorm normalized name: Calcium Carbonate
DrugBank: Calcium carbonate (DB06724)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Calcium carbonate (Ca) 400 mg/d + vitamin D 200 IU/D (Control group)
Trial: 12667363
Drug: E(2)V 1.0
FDA approved: no
EMA approved: no
PMDA approved: no
Description: E(2)V 1.0 mg/d + MPA 2 mg/d + Ca 400 mg/d (Treatment group 1)
Trial: 12667363
Drug: E(2)V 1.0
FDA approved: no
EMA approved: no
PMDA approved: no
Description: E(2)V 1.0 mg/d + MPA 2 mg/d + Ca 400 mg/d + vitamin D 200 IU/d (Treatment group 2)
Trial: 12667363
Drug: E(2)V 1.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: E(2)V 1.5 mg/d + MPA 2 mg/d + Ca 400 mg/d + vitamin D 200 IU/d (Treatment group 3)
Trial: 7818118
Drug: 3 mL
RxNorm normalized name: WATER,INHL 3 ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 mL of 1.5% lidocaine with epinephrine (1:200,000) IV
Trial: 7818118
Drug: 3 mL
RxNorm normalized name: WATER,INHL 3 ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 mL of normal saline IV
Trial: 1703451
Drug: Carboplatin 300
RxNorm normalized name: Carboplatin
DrugBank: Carboplatin (DB00958)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Carboplatin 300 mg/m2 and fluoro‐uracil 1000 mg/m2/d administered in continuous IV infusion for 96 h every 4 weeks (group 1)
Trial: 1703451
Drug: Carboplatin 350
RxNorm normalized name: Carboplatin
DrugBank: Carboplatin (DB00958)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Carboplatin 350 mg/m2 and fluoro‐uracil administered at the same dose every 3 weeks (group II)
Trial: 1703451
Drug: Both groups
RxNorm normalized name: Streptococcus viridans group
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Both groups (combined therapy with carboplatin and fluoro‐uracil)
Trial: 28446631
Drug: Balanced protein‐energy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Balanced protein‐energy supplementation of 500 mL milk/d plus a 10‐μg vitamin B‐12 tablet/d (M+B‐12 group)
Trial: 28446631
Drug: Milk (500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Milk (500 mL/d) plus a placebo tablet (M+P group)
Trial: 28446631
Drug: Placebo tablet
RxNorm normalized name: placebo Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo tablet alone (P group)
Trial: 17978289
Drug: S-1 (80
FDA approved: no
EMA approved: no
PMDA approved: no
Description: S-1 (80 mg/m²/day for 4 weeks followed by 2 weeks off, for 1 year)
Trial: 8160603
Drug: Sequential monophasic
RxNorm normalized name: Monobasic Potassium Phosphate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sequential monophasic shocks
Trial: 6084754
Drug: Tamoxifen (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tamoxifen (20 mg b.i.d. for 10 days)
Trial: 25288348
Drug: Intra-articular glucocorticoid
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intra-articular glucocorticoid injection (40 mg triamcinolone acetonide)
Trial: 26654244
Drug: Single 300
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Single 300 ml dose of anthocyanin-rich cherry juice
Trial: 26654244
Drug: 3 x
RxNorm normalized name: Xenon (133 xe)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 x 100 ml doses of anthocyanin-rich cherry juice
Trial: 23828481
Drug: Endobronchial valve
RxNorm normalized name: VALVE
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Endobronchial valve therapy (EBV)
Trial: 17690310
Drug: Conservative therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conservative therapy (control)
Trial: 20820148
Drug: Fenoldopam 0.05-mcg/kg/min
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fenoldopam 0.05-mcg/kg/min
Trial: 19127796
Drug: Short-term amoxicillin-clavulanic
RxNorm normalized name: hydrogen peroxide
DrugBank: Hydrogen peroxide (DB11091)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Short-term amoxicillin-clavulanic acid
Trial: 19127796
Drug: Long-term amoxicillin-clavulanic
RxNorm normalized name: amoxicillin / clavulanate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Long-term amoxicillin-clavulanic acid
Trial: 17085378
Drug: Sequential oral
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sequential oral and transdermal estradiol regimen (2 mg oral micronized 17beta‐estradiol/day or 1.5 mg 17beta‐estradiol gel/day) combined with oral dydrogesterone (10 mg/day, 12 days/month) for 1 year
Trial: 1796408
Drug: Heparin intravenously
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Heparin intravenously 30,000-40,000 U daily
Trial: 21406956
Drug: Cognitive stimulation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cognitive stimulation intervention for 2 months, weekly group sessions.
Trial: 10500058
Drug: Ibuprofen (800
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ibuprofen (800 mg 3 times daily)
Trial: 12600812
Drug: Tiagabine (add-on
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tiagabine (add-on therapy)
Trial: 10368798
Drug: Goserelin 3.6
RxNorm normalized name: goserelin 3.6 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Goserelin 3.6 mg implant four weekly + placebo tablets daily (Group C)
Trial: 10368798
Drug: Goserelin 3.6
RxNorm normalized name: goserelin 3.6 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Goserelin 3.6 mg implant four weekly + estradiol valerate 2 mg daily with norethisterone 5 mg from days 21-28 of a 28-day cycle (Group B)
Trial: 10368798
Drug: Placebo implant
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo implant four weekly + placebo tablets daily (Group A)
Trial: 8897354
Drug: 5,6 benzo‐[alpha]‐pyrone
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5,6 benzo‐[alpha]‐pyrone (coumarin 400 mg/day) for six months
Trial: 8897354
Drug: Heat therapy
RxNorm normalized name: CVS Neck Arm & Leg Heat Therapy Patch
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Heat therapy (microwave) plus compression garments for six months
Trial: 8897354
Drug: Benzopyrones for
RxNorm normalized name: benzopyrene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Benzopyrones for 12 months plus heat treatment for six months
Trial: 8897354
Drug: Heat therapy
RxNorm normalized name: CVS Neck Arm & Leg Heat Therapy Patch
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Heat therapy plus either placebo or benzopyrone
Trial: 6711782
Drug: 0.4 mg
RxNorm normalized name: biotin 0.4 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.4 mg buprenorphine pre‐emptively for postoperative pain
Trial: 6711782
Drug: Morphine or
RxNorm normalized name: morphine Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Morphine or placebo
Trial: 28993346
Drug: Immediate active
RxNorm normalized name: Activated Charcoal
DrugBank: Activated charcoal (DB09278)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Immediate active treatment with intravenous abatacept
Trial: 28993346
Drug: Delayed treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Delayed treatment arm
Trial: 27260839
Drug: Talactoferrin (TLf)
RxNorm normalized name: Talactoferrin alfa
DrugBank: Talactoferrin alfa (DB05426)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Talactoferrin (TLf) 150 mg/kg every 12 hours for 28 days
Trial: 24929798
Drug: Moderate or
RxNorm normalized name: Medicated Pad or Tape
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Moderate or intense supervised exercise training thrice-weekly for 12 weeks
Trial: 12424329
Drug: Lycopene supplementation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lycopene supplementation (30 mg of lycopene from tomato oleoresin extract)