AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 2543280
Drug: Intranasal alpha
RxNorm normalized name: alpha tocopherol
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intranasal alpha 2b interferon (IFN) 5 x 10(6) IU on day 1 and 2.5 x 10(6) IU on each subsequent day for 5 days
Trial: 23485660
Drug: Multimodal manual
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Multimodal manual treatment approach (joint mobilization, neural mobilization, and exercise)
Trial: 23485660
Drug: Multimodal manual
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Multimodal manual treatment approach
Trial: 17205144
Drug: Valsartan (Diovan)
RxNorm normalized name: Valsartan
DrugBank: Valsartan (DB00177)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Valsartan (Diovan) 80 mg/day for 7 days
Trial: 15132875
Drug: Mosapride 5
RxNorm normalized name: mosapride 5 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Mosapride 5 mg three times daily for 4 weeks
Trial: 15132875
Drug: Domperidone 10
RxNorm normalized name: domperidone 10 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Domperidone 10 mg three times daily for 4 weeks
Trial: 11402745
Drug: Acupuncture treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acupuncture treatment for two weeks
Trial: 11402745
Drug: Naproxen 500
RxNorm normalized name: naproxen 500 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Naproxen 500 mg twice daily for ten days
Trial: 9143861
Drug: Carvedilol (25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Carvedilol (25 mg to 50 mg daily after 6 weeks)
Trial: 1826192
Drug: ANF infusion
RxNorm normalized name: Duo Fusion
DrugBank: Magnesium hydroxide (DB09104)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: ANF infusion at 1 pmol/kg/min
Trial: 1826192
Drug: ANF infusion
RxNorm normalized name: Duo Fusion
DrugBank: Magnesium hydroxide (DB09104)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: ANF infusion at 3 pmol/kg/min
Trial: 1826192
Drug: ANF infusion
RxNorm normalized name: Duo Fusion
DrugBank: Magnesium hydroxide (DB09104)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: ANF infusion at 10 pmol/kg/min
Trial: 25867537
Drug: Second-line chemotherapy
RxNorm normalized name: Gallus gallus gizzard lining preparation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Second-line chemotherapy
Trial: 26367239
Drug: Third-line chemotherapy
RxNorm normalized name: Gallus gallus gizzard lining preparation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Third-line chemotherapy
Trial: 26084590
Drug: Etanercept continuous
RxNorm normalized name: Etanercept
DrugBank: Etanercept (DB00005)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Etanercept continuous regimen (50 mg/week)
Trial: 17080277
Drug: Perianal local
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Perianal local anesthesia (40 ml of ropivacaine, 4.75 mg/ml, plus 15 ml of ropivacaine, 2 mg/ml)
Trial: 14971717
Drug: Flavonoid extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Flavonoid extract (Colladeen, 320 mg oligomeric procyanidins)
Trial: 10186469
Drug: Ribosomal vaccine
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ribosomal vaccine (Ribomunyl)
Trial: 2968060
Drug: Loratadine 80
RxNorm normalized name: Loratadine
DrugBank: Loratadine (DB00455)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Loratadine 80 mg
Trial: 18310201
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (no emollient therapy)
Trial: 12823564
Drug: New antiepileptic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: New antiepileptic drugs (AEDs) in monotherapy
Trial: 31822251
Drug: Thrombolysis treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Thrombolysis treatment
Trial: 8396000
Drug: No treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No treatment until relapse
Trial: 3714767
Drug: Atropine sulfate
RxNorm normalized name: Atropine Sulfate
DrugBank: Atropine (DB00572)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Atropine sulfate 2 mg/70 kg
Trial: 3714767
Drug: Atropine sulfate
RxNorm normalized name: Atropine Sulfate
DrugBank: Atropine (DB00572)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Atropine sulfate 4 mg/70 kg
Trial: 24610413
Drug: Royal jelly
RxNorm normalized name: ROYAL JELLY
DrugBank: Royal jelly (DB14250)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Royal jelly supplementation (1,000 mg daily for 8 weeks)
Trial: 10761763
Drug: Fludarabine (Flu)
DrugBank: Fludarabine (DB01073)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fludarabine (Flu) 25 mg/m2 for five consecutive days every four weeks
Trial: 10761763
Drug: Cladribine (CdA)
RxNorm normalized name: Cladribine
DrugBank: Cladribine (DB00242)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Cladribine (CdA) 0.14 mg/kg for five consecutive days every four weeks
Trial: 10761763
Drug: Cross-over treatment
RxNorm normalized name: Red Cross Canker Sore
DrugBank: Benzocaine (DB01086)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Cross-over treatment after failure
Trial: 1407981
Drug: Topical medication
RxNorm normalized name: Procto-Med Topical Product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical medication and/or laser trabeculoplasty
Trial: 6726903
Drug: Preoperative radiation
RxNorm normalized name: allantoin
DrugBank: Allantoin (DB11100)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Preoperative radiation therapy (1,600 rad for 4 days)
Trial: 6726903
Drug: Contemporary surgery
RxNorm normalized name: capsaicin
DrugBank: Capsaicin (DB06774)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Contemporary surgery without preoperative radiation therapy
Trial: 30509743
Drug: 100 μg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 μg/kg oral morphine sulphate
Trial: 24856057
Drug: Oxytocin nasal
RxNorm normalized name: oxytocin Nasal Spray
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oxytocin nasal spray (20 international units)
Trial: 23768677
Drug: STOP IT
RxNorm normalized name: DIPHENHYDRAMINE HYDROCHLORIDE 2 g in 100 mL TOPICAL GEL [Walgreens Stop Itch Gel]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: STOP IT program (integrated treatment for PTSD and smoking)
Trial: 20805642
Drug: Control (no
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control (no intravenous methylprednisolone)
Trial: 15928250
Drug: DHEA (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: DHEA (100 mg/d)
Trial: 15928250
Drug: APZ (0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: APZ (0.5 mg)
Trial: 15928250
Drug: DHEA and
RxNorm normalized name: cytarabine and daunorubicin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: DHEA and APZ in combination
Trial: 12181240
Drug: 5-FU plus
RxNorm normalized name: 5-FU
DrugBank: Fluorouracil (DB00544)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: 5-FU plus cisplatin (FUP) - continuous 5-FU 1000 mg/m2/day for 5 days plus cisplatin 100 mg/m2 on day 1 or day 2
Trial: 12181240
Drug: 5-FU (FU)
RxNorm normalized name: 5-FU
DrugBank: Fluorouracil (DB00544)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: 5-FU (FU) - 5-FU 500 mg/m2/day for 5 days
Trial: 10600332
Drug: ALLERVAX CAT
RxNorm normalized name: cat hair extract
DrugBank: Felis catus hair (DB10499)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: ALLERVAX CAT (750 microg/dose)
Trial: 8635183
Drug: L-deprenyl (10
FDA approved: no
EMA approved: no
PMDA approved: no
Description: L-deprenyl (10 mg daily) as an adjunct to low-dose bromocriptine (up to 25 mg daily)
Trial: 8635183
Drug: L-deprenyl plus
RxNorm normalized name: L-deprenyl-D2 C-11
DrugBank: L-deprenyl-D2 C-11 (DB12650)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: L-deprenyl plus bromocriptine
Trial: 2126361
Drug: Clonidine (150
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Clonidine (150 micrograms in a single oral dose)
Trial: 2126361
Drug: Insulin (0.15
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Insulin (0.15 IU/kg BW in an i.v. bolus)
Trial: 832432
Drug: NaCl supplements
FDA approved: no
EMA approved: no
PMDA approved: no
Description: NaCl supplements of 200 mEq/day
Trial: 832432
Drug: Daily mixture
RxNorm normalized name: brown mixture
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Daily mixture of NaHCO3 (100 mEq) and NaCl (100 mEq)
Trial: 30723316
Drug: Citalopram (dose-dependent)
DrugBank: Citalopram (DB00215)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Citalopram (dose-dependent)
Trial: 30723316
Drug: Citalopram (high
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Citalopram (high dose)
Trial: 30723316
Drug: Citalopram (low
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Citalopram (low dose)
Trial: 28723597
Drug: Intra tympanic
RxNorm normalized name: somatropin
DrugBank: Somatotropin (DB00052)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intra tympanic Gentamicin (40 mgs/ml)
Trial: 28723597
Drug: Intra tympanic
RxNorm normalized name: somatropin
DrugBank: Somatotropin (DB00052)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intra tympanic Dexamethasone (0.5 ml, 4 mgs/ml)
Trial: 28723597
Drug: Intra tympanic
RxNorm normalized name: somatropin
DrugBank: Somatotropin (DB00052)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intra tympanic Normal Saline (0.5 ml)
Trial: 22193396
Drug: Retrograde intravenous
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Retrograde intravenous delivery of 100 million bone marrow mononuclear cells (BMMC) through the IVC route
Trial: 11040903
Drug: Oral fluorescein
RxNorm normalized name: Fluorescein
DrugBank: Fluorescein (DB00693)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Oral fluorescein angiography (OFA)
Trial: 3757511
Drug: High dose
RxNorm normalized name: INFLUENZA VACCINE HIGH DOSE 0.5ML SYR
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High dose regimen (400 mg/day RU 486 X 4 days or 200 mg/day X 4 days)
Trial: 3757511
Drug: Medium dose
RxNorm normalized name: TRIGLYCERIDES,MEDIUM CHAIN
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medium dose regimen (100 mg/day X 7 days)
Trial: 3757511
Drug: All treatment
RxNorm normalized name: UNDECYLENIC ACID 8 g in 30 mL / TOLNAFTATE 1 g in 30 mL TOPICAL LIQUID [Fugal nall treatment]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: All treatment groups (including both high and medium doses)
Trial: 28254462
Drug: ASP3652 300
FDA approved: no
EMA approved: no
PMDA approved: no
Description: ASP3652 300 mg twice daily
Trial: 27323445
Drug: Acupuncture treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acupuncture treatment (Zhongwan, Tianshu, Daheng, Daimai, Shuidao, Waiguan, Zulinqi with electroacupuncture stimulation at 2 Hz/100 Hz, 4‐8 mA for 20 min, once every other day for 8 weeks)
Trial: 27323445
Drug: Health education
RxNorm normalized name: Healthy Mama
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Health education (restraining wine or liquor and salt intake, stopping smoking, increasing physical activities, regular daily life habit)
Trial: 24198629
Drug: Silodosin 8
RxNorm normalized name: silodosin 8 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Silodosin 8 mg once daily for 12 weeks
Trial: 24612148
Drug: Tamsulosin 0.4
RxNorm normalized name: tamsulosin 0.4 mg oral capsule
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tamsulosin 0.4 mg once daily for 12 weeks
Trial: 20687837
Drug: 50 mg
RxNorm normalized name: talc 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 50 mg of arterolane once daily for 7 days
Trial: 20687837
Drug: 100 mg
RxNorm normalized name: urea 100 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 mg of arterolane once daily for 7 days
Trial: 20687837
Drug: 200 mg
RxNorm normalized name: RNA 200 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 200 mg of arterolane once daily for 7 days
Trial: 18984430
Drug: Indapamide (IND)
RxNorm normalized name: Indapamide
DrugBank: Indapamide (DB00808)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Indapamide (IND) 2.5 mg once daily
Trial: 18984430
Drug: Bendroflumethiazide (BDZ)
RxNorm normalized name: Bendroflumethiazide
DrugBank: Bendroflumethiazide (DB00436)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Bendroflumethiazide (BDZ) 2.5 mg once daily
Trial: 15836686
Drug: AAI-guided sevoflurane
RxNorm normalized name: Sevoflurane
DrugBank: Sevoflurane (DB01236)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: AAI-guided sevoflurane titration (target = 20 +/- 5)
Trial: 15836686
Drug: Clinical signs-guided
RxNorm normalized name: DuoCare Clinical
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Clinical signs-guided sevoflurane titration
Trial: 11918749
Drug: L-Arg supplementation
RxNorm normalized name: L-Arg
DrugBank: Arginine (DB00125)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: L-Arg supplementation (IV for three days)
Trial: 11918749
Drug: L-Arg administration
RxNorm normalized name: L-Arg
DrugBank: Arginine (DB00125)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: L-Arg administration
Trial: 10341399
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of maternal age, fetal nuchal translucency thickness, maternal serum free beta‐hCG, and PAPP‐A
Trial: 8730942
Drug: Dothiepin (150
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dothiepin (150 mg/day)
Trial: 23672237
Drug: Cilostazol (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cilostazol (100 mg orally twice daily for 24 weeks)
Trial: 15968883
Drug: Ciclesonide (640
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ciclesonide (640 microg ex‐actuator, equivalent to 800 microg ex‐valve, via hydrofluoroalkane metered‐dose inhaler)
Trial: 15968883
Drug: Erythromycin (500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Erythromycin (500 mg PO)
Trial: 15968883
Drug: Combined administration
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combined administration of ciclesonide and erythromycin
Trial: 12056936
Drug: Civamide (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Civamide (100 microL of 0.025% civamide, 25 microg) once daily for 7 days
Trial: 12056936
Drug: Vehicle (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vehicle (100 microL) once daily for 7 days
Trial: 7862216
Drug: Paclitaxel 135
RxNorm normalized name: Paclitaxel
DrugBank: Paclitaxel (DB01229)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Paclitaxel 135 mg/m2
Trial: 8708510
Drug: Paclitaxel (both
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paclitaxel (both doses)
Trial: 8708510
Drug: Paclitaxel (high
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paclitaxel (high dose)
Trial: 1746996
Drug: Famotidine 20
RxNorm normalized name: famotidine 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Famotidine 20 mg BID
Trial: 1746996
Drug: Famotidine 40
RxNorm normalized name: famotidine 40 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Famotidine 40 mg HS
Trial: 1746996
Drug: Famotidine 40
RxNorm normalized name: famotidine 40 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Famotidine 40 mg HS and Famotidine 20 mg BID
Trial: 6213641
Drug: Preparation (informative
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Preparation (informative preoperative interview)
Trial: 30823947
Drug: LISA (less
FDA approved: no
EMA approved: no
PMDA approved: no
Description: LISA (less invasive surfactant administration)
Trial: 30823947
Drug: INSURE (INtubation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: INSURE (INtubation SURfactant administration and Extubation)
Trial: 27973989
Drug: Saccharomyces boulardii
RxNorm normalized name: Saccharomyces boulardii
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Saccharomyces boulardii (SB) plus Amoxicillin-Clavulanate (AC)
Trial: 27973989
Drug: Amoxicillin-Clavulanate (AC)
RxNorm normalized name: amoxicillin / clavulanate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Amoxicillin-Clavulanate (AC) alone
Trial: 21494229
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of diet and exercise (D+E)
Trial: 19466657
Drug: Partial or
RxNorm normalized name: Medicated Pad or Tape
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Partial or subtotal thyroid gland removal treatment (group B)
Trial: 9615847
Drug: Preoperative ketoprofen
RxNorm normalized name: Ketoprofen
DrugBank: Ketoprofen (DB01009)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Preoperative ketoprofen 100 mg i.v., 12 mg/h during surgery and for 48 hours afterwards
Trial: 9615847
Drug: 100 mg
RxNorm normalized name: urea 100 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 mg ketoprofen as a bolus injection before the end of surgery, thereafter 12 mg/h ketoprofen continuously for 48 hours
Trial: 3325229
Drug: Isosorbide-5-mononitrate (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Isosorbide-5-mononitrate (20 mg)
Trial: 24832384
Drug: Extended-release niacin/laropiprant
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Extended-release niacin/laropiprant
Trial: 19486449
Drug: Pantoprazole (40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pantoprazole (40 mg/day) for 28 days
Trial: 19486449
Drug: Ranitidine (300
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ranitidine (300 mg o.d.) for 60 days
Trial: 9530125
Drug: daily exercise
FDA approved: no
EMA approved: no
PMDA approved: no
Description: daily exercise program (55% peak oxygen uptake)
Trial: 8556776
Drug: Hydrochlorothiazide (25-50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hydrochlorothiazide (25-50 mg daily for at least six months)
Trial: 8556776
Drug: Zinc supplementation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Zinc supplementation (500 mg daily for 30 days)
Trial: 8556776
Drug: Magnesium chloride
RxNorm normalized name: Magnesium Chloride
DrugBank: Magnesium chloride (DB09407)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Magnesium chloride supplementation (1 g daily for 30 days)
Trial: 323705
Drug: 2.5 mg
RxNorm normalized name: biotin 2.5 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2.5 mg of estrogen
Trial: 323705
Drug: 5.0 mg
RxNorm normalized name: RUXOLITINIB 5.0 mg ORAL TABLET [JAKAFI]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5.0 mg of estrogen
Trial: 323705
Drug: 1.8 g
RxNorm normalized name: Calciquid, 1.8 g/5 mL oral syrup
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1.8 g of clofibrate
Trial: 28871620
Drug: Oropharyngeal surfactant
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oropharyngeal surfactant (1.5 mL of Curosurf) with sustained inflation manoeuvre (SIM)
Trial: 27919362
Drug: OM3‐CA (omega‐3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: OM3‐CA (omega‐3 carboxylic acids) 2, 3, or 4 g/d
Trial: 24534599
Drug: Optimal medical
RxNorm normalized name: Optima Plus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Optimal medical therapy goals (aspirin use, blood pressure control, cholesterol levels, glucose levels, nonsmoking status, body mass index, exercise frequency)
Trial: 15893104
Drug: Delayed treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Delayed treatment control group (DTC)
Trial: 9477013
Drug: Scaling with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Scaling with systemic metronidazole plus amoxicillin and supragingival irrigation with chlorhexidine digluconate
Trial: 11281339
Drug: Lisinopril (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lisinopril (20 mg/day)
Trial: 7662221
Drug: Hydrochlorothiazide (12.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hydrochlorothiazide (12.5 mg/day)
Trial: 2527541
Drug: Cilazapril 1.25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cilazapril 1.25 or 2.5 mg
Trial: 824468
Drug: Low-dose penicillin
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose penicillin (procaine penicillin G, 600,000 units intramuscularly, every 12 hours for up to ten days)
Trial: 824468
Drug: High-dose penicillin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose penicillin (procaine penicillin G, same regimen as low-dose plus intravenous aqueous penicillin G, 10 million units daily for the first three days)
Trial: 824468
Drug: High-dose penicillin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose penicillin
Trial: 824468
Drug: Low-dose penicillin
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose penicillin
Trial: 824468
Drug: Low-dose penicillin
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose penicillin and high-dose penicillin
Trial: 23401601
Drug: 100 mg
RxNorm normalized name: urea 100 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 mg loading dose of leflunomide (LEF) for 3 days, followed by 20 mg LEF daily for 3 months
Trial: 23401601
Drug: 20 mg
RxNorm normalized name: urea 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 20 mg fixed dose of leflunomide (LEF) for 3 days, followed by 20 mg LEF daily for 3 months
Trial: 23401601
Drug: Both groups
RxNorm normalized name: Streptococcus viridans group
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Both groups (loading-dose and fixed-dose)
Trial: 19419359
Drug: Spinal anesthesia
RxNorm normalized name: Bos taurus spinal cord preparation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Spinal anesthesia (SA) with bupivacaine 15 mg, 0.15 mg of intrathecal morphine and 15 microg of fentanyl
Trial: 26363481
Drug: Transvaginal cervical
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transvaginal cervical length (TVCL) assessment and digital exams monthly from 16‐28 weeks with standard management algorithm for activity restriction and cerclage
Trial: 26363481
Drug: Monthly digital
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Monthly digital cervical examinations without routine TVCL ultrasound