AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 20728083
Drug: Oral misoprostol
RxNorm normalized name: Misoprostol
DrugBank: Misoprostol (DB00929)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Oral misoprostol 600 μg
Trial: 20728083
Drug: Vaginal misoprostol
RxNorm normalized name: Misoprostol
DrugBank: Misoprostol (DB00929)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Vaginal misoprostol 400 μg
Trial: 19637103
Drug: Cocaine/Stimulant use
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cocaine/Stimulant use
Trial: 16713344
Drug: Ropinirole (exact
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ropinirole (exact dosage and duration not specified)
Trial: 11304774
Drug: Accelerated-intensified CEF
RxNorm normalized name: Serum prothrombin conversion accelerator
DrugBank: Coagulation factor VII human (DB13150)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Accelerated-intensified CEF (HD-CEF14) with G-CSF (cyclophosphamide 1,000 mg/m(2), epirubicin 80 mg/m(2), fluorouracil 600 mg/m(2), administered every 14 days)
Trial: 11304774
Drug: Standard CEF
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard CEF (CEF21) (cyclophosphamide 600 mg/m(2), epirubicin 60 mg/m(2), fluorouracil 600 mg/m(2), administered every 21 days)
Trial: 3318902
Drug: Adriamycin 70
RxNorm normalized name: Adriamycin
DrugBank: Doxorubicin (DB00997)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Adriamycin 70 mg m‐2 i.v. 3‐weekly for 8 cycles (Regimen A)
Trial: 3318902
Drug: Adriamycin 35
RxNorm normalized name: Adriamycin
DrugBank: Doxorubicin (DB00997)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Adriamycin 35 mg m‐2 i.v. 3‐weekly for 16 courses (Regimen B)
Trial: 27323446
Drug: Acupuncture therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acupuncture therapy (twice a week) and Acetylcysteine capsule (200 mg/time, t.i.d.) for 12 weeks
Trial: 27323446
Drug: Acetylcysteine capsule
RxNorm normalized name: Acetylcysteine
DrugBank: Acetylcysteine magnesium (DB14080)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Acetylcysteine capsule (200 mg/time, t.i.d.) for 12 weeks
Trial: 22458987
Drug: 12-month collaborative
RxNorm normalized name: moth bean
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 12-month collaborative care intervention (problem-solving therapy and/or pharmacotherapy, telephone symptom monitoring/relapse prevention, behavioral activation and patient navigation support)
Trial: 20039955
Drug: Medication-overuse headache
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medication-overuse headache (MOH)
Trial: 20039955
Drug: Medication-overuse headache
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medication-overuse headache (MOH) and episodic headache (EH)
Trial: 18930093
Drug: Intraderal TIV
RxNorm normalized name: influenza A virus (H1N1) antigen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intraderal TIV (0.1 ml injection, 9 microg HA/strain)
Trial: 18930093
Drug: Intramuscular vaccine
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intramuscular vaccine (0.5 ml injection, 15 microg HA/strain)
Trial: 9162315
Drug: Treatment of
RxNorm normalized name: DRUGS FOR TREATMENT OF LEPRA
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Treatment of pulmonary tuberculosis
Trial: 3925656
Drug: 800 mg
RxNorm normalized name: bran 800 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 800 mg nitroglycerin ointment 2%
Trial: 28073199
Drug: Intrarectal local
RxNorm normalized name: zinc oxide
DrugBank: Zinc oxide (DB09321)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intrarectal local anesthetic administration (lidocaine 5 ml 10%) and lidocaine local spray 15% (Group B)
Trial: 28073199
Drug: Periprostatic block
RxNorm normalized name: Ivy Block
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Periprostatic block anesthesia (lidocaine 10 ml 10%) (Group C)
Trial: 24359138
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of intraligamentary injection + buccal infiltration + IANB
Trial: 24359138
Drug: Traditional IANB
RxNorm normalized name: sodium fluoride
DrugBank: Sodium fluoride (DB09325)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Traditional IANB injection
Trial: 20332351
Drug: Twice-daily exenatide
RxNorm normalized name: clindamycin
DrugBank: Clindamycin (DB01190)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Twice-daily exenatide (10 microg)
Trial: 12105827
Drug: Gastroenterologist-administered propofol
RxNorm normalized name: Propofol
DrugBank: Propofol (DB00818)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Gastroenterologist-administered propofol
Trial: 10432168
Drug: Benfluorex (150
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Benfluorex (150 mg t.i.d.)
Trial: 8523379
Drug: Quinapril (10-40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Quinapril (10-40 mg/day)
Trial: 6458582
Drug: 0.05 mg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.05 mg/kg body weight 13‐cis‐retinoic acid
Trial: 6458582
Drug: 0.5 mg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.5 mg/kg body weight 13‐cis‐retinoic acid
Trial: 6458582
Drug: 1.0 mg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1.0 mg/kg body weight 13‐cis‐retinoic acid
Trial: 27903087
Drug: Same-day cervical
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Same-day cervical preparation with osmotic dilator and misoprostol
Trial: 27903087
Drug: Overnight cervical
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Overnight cervical preparation with osmotic dilator and misoprostol
Trial: 25745875
Drug: Intravitreal aflibercept
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravitreal aflibercept 2 mg
Trial: 23342996
Drug: MSP142 vaccine
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MSP142 vaccine (50 μg) administered intramuscularly with adjuvant system AS01
Trial: 15078748
Drug: Fexofenadine (FEX),
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fexofenadine (FEX), 180 mg
Trial: 15078748
Drug: Montelukast (ML),
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Montelukast (ML), 10 mg
Trial: 3141856
Drug: Alpha-2-interferon (18
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Alpha-2-interferon (18 x 10(6) U 3x/week weekly i.m.)
Trial: 3141856
Drug: Alpha-2-interferon in
RxNorm normalized name: Interferon alpha-2B
DrugBank: Interferon alfa-2b (DB00105)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Alpha-2-interferon in combination with vinblastine (0.1 mg/kg every third week i.v.)
Trial: 23704674
Drug: Metformin plus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metformin plus lifestyle
Trial: 27803118
Drug: Not applicable
RxNorm normalized name: AIR 1000 mL in 1 L NOT APPLICABLE GAS
DrugBank: Urea (DB03904)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Not applicable (treatment failure comparison)
Trial: 26141467
Drug: 13 mL
RxNorm normalized name: ethanol 0.713 ML/ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 13 mL 10% tPA
Trial: 26141467
Drug: 13 mL
RxNorm normalized name: ethanol 0.713 ML/ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 13 mL normal saline
Trial: 20506261
Drug: Aspirin, NSAID,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Aspirin, NSAID, and paracetamol use
Trial: 19076728
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of vitamin C and BH(4)
Trial: 11442216
Drug: Meglumine antimonate
RxNorm normalized name: meglumine antimonate
DrugBank: Meglumine antimoniate (DB13732)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Meglumine antimonate (20 mg Sb/kg/day) for 10 days
Trial: 11442216
Drug: Meglumine antimonate
RxNorm normalized name: meglumine antimonate
DrugBank: Meglumine antimoniate (DB13732)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Meglumine antimonate (20 mg Sb/kg/day) for 20 days
Trial: 8061763
Drug: Injection pen
RxNorm normalized name: Albiglutide 30 mg powder for solution for injection pen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Injection pen for growth hormone administration (Nordiject)
Trial: 2853731
Drug: Calcium supplementation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Calcium supplementation (600 mg/day) for 4 weeks
Trial: 29474546
Drug: Thrice-weekly intervention
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Thrice-weekly intervention messages, plus texted primary care appointment reminders and a monthly text message requesting confirmation of study participation
Trial: 29474546
Drug: Texted reminders
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Texted reminders and monthly messages alone
Trial: 29474546
Drug: Thrice-weekly intervention
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Thrice-weekly intervention messages
Trial: 9857618
Drug: ELISA test
RxNorm normalized name: mumps skin test antigen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: ELISA test for detection of antibodies against pertussis toxin
Trial: 7634134
Drug: Mouthrinse with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Mouthrinse with 0.2% chlorhexidine (CHX) and 0.3% triclosan in soya oil, used twice daily for 4 days
Trial: 148936
Drug: 3 mg
RxNorm normalized name: boron 3 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 mg of phenytoin/kg body weight/day for five days followed by 6 mg/kg body weight/day (group 1)
Trial: 148936
Drug: 6 mg
RxNorm normalized name: boron 6 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 6 mg of phenytoin/kg body weight/day for five days followed by 6 mg/kg body weight/day (group 2)
Trial: 148936
Drug: Phenytoin concentration
RxNorm normalized name: Phenytoin
DrugBank: Phenytoin (DB00252)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Phenytoin concentration higher than 14 micromol/l on day 5
Trial: 25822861
Drug: Gel hypotonic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Gel hypotonic super-ORS containing zinc (group 2)
Trial: 23799163
Drug: Rhinophototherapy with
RxNorm normalized name: Primatene with ephedrine Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Rhinophototherapy with topical mometasone furoate 200 mcg/day and levocetirizine 5 mg/day, applied twice a week for three weeks.
Trial: 23799163
Drug: Topical mometasone
RxNorm normalized name: mometasone Topical Cream
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical mometasone furoate 200 mcg/day and levocetirizine 5 mg/day (Control group).
Trial: 21075562
Drug: Standard practice
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard practice classroom-delivered Drug Awareness intervention
Trial: 19996663
Drug: General anesthesia
RxNorm normalized name: Ethers for general anesthesia
FDA approved: no
EMA approved: no
PMDA approved: no
Description: General anesthesia (sevoflurane and intravenous fentanyl)
Trial: 11344347
Drug: Inhaled budesonide
RxNorm normalized name: budesonide Inhalation Suspension
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhaled budesonide (withdrawal group)
Trial: 9484875
Drug: Grepafloxacin 400
RxNorm normalized name: grepafloxacin 400 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Grepafloxacin 400 mg od
Trial: 9484875
Drug: Grepafloxacin 600
RxNorm normalized name: grepafloxacin 600 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Grepafloxacin 600 mg od
Trial: 7910229
Drug: Lisinopril (5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lisinopril (5 mg initial dose, then 10 mg daily)
Trial: 7910229
Drug: Transdermal glyceryl
RxNorm normalized name: glyceryl
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transdermal glyceryl trinitrate (GTN, 10 mg daily after intravenous for the first 24 hours)
Trial: 7910229
Drug: Combined administration
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combined administration of lisinopril and GTN
Trial: 29562612
Drug: Comprehensive nutritional
RxNorm normalized name: Ocean Blue Nutritionals Omega-3 1450 Pill
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Comprehensive nutritional and dietary intervention including vitamin/mineral supplements, essential fatty acids, Epsom salt baths, carnitine, digestive enzymes, and a healthy gluten‐free, casein‐free, soy‐free (HGCSF) diet
Trial: 9771058
Drug: Non-treatment group
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Non-treatment group (control)
Trial: 27430332
Drug: EuroFIT program
FDA approved: no
EMA approved: no
PMDA approved: no
Description: EuroFIT program (lifestyle intervention) delivered over 12 weekly, 90-minute sessions combining classroom discussion with graded physical activity.
Trial: 9157579
Drug: Desirudin (10,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Desirudin (10, 15, or 20 mg bid)
Trial: 9157579
Drug: Unfractionated heparin
RxNorm normalized name: Unfractionated heparin
DrugBank: Heparin (DB01109)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Unfractionated heparin (5000 IU tid)
Trial: 8143568
Drug: Nonrigid reclining
RxNorm normalized name: refined almond oil
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nonrigid reclining infant seat (3‐h sessions, twice a day for 6‐ to 7‐week period)
Trial: 29209863
Drug: Intervention Group
RxNorm normalized name: Streptococcus viridans group
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intervention Group (IG) - One-time clinical medication review
Trial: 16047459
Drug: High-dose omeprazole
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose omeprazole (200 mg/day)
Trial: 16047459
Drug: Low-dose omeprazole
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose omeprazole (80 mg/day)
Trial: 16047459
Drug: High-dose and
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose and low-dose omeprazole
Trial: 16047459
Drug: Serum albumin
RxNorm normalized name: Serum albumin
DrugBank: Albumin human (DB00062)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Serum albumin level <3 g/dL
Trial: 10515650
Drug: Active non-steroidal
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Active non-steroidal anti-inflammatory drug (NSAID) for 6 weeks
Trial: 8536776
Drug: TER 5
RxNorm normalized name: Judkins Catheter 5.0
FDA approved: no
EMA approved: no
PMDA approved: no
Description: TER 5 mg once in the morning (AM)
Trial: 8536776
Drug: TER 5
RxNorm normalized name: Judkins Catheter 5.0
FDA approved: no
EMA approved: no
PMDA approved: no
Description: TER 5 mg once in the evening (PM)
Trial: 8536776
Drug: DOX 4
RxNorm normalized name: dextromethorphan
DrugBank: Dextromethorphan (DB00514)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: DOX 4 mg once in the morning (AM)
Trial: 8536776
Drug: DOX 4
RxNorm normalized name: dextromethorphan
DrugBank: Dextromethorphan (DB00514)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: DOX 4 mg once in the evening (PM)
Trial: 1775604
Drug: Tacrine (THA),
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tacrine (THA), a cholinesterase inhibitor
Trial: 7274074
Drug: Aminoglutethimide (Elipten)
RxNorm normalized name: Aminoglutethimide
DrugBank: Aminoglutethimide (DB00357)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Aminoglutethimide (Elipten) 250-1500 mg/d by mouth
Trial: 7274074
Drug: Aminoglutethimide in
RxNorm normalized name: Product containing aminoglutethimide in oral dose form (medicinal product form)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Aminoglutethimide in combination with cytostatic drugs
Trial: 28657769
Drug: Monurelle Biogel®
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Monurelle Biogel® vaginal gel
Trial: 17575680
Drug: 2HRZE3/6HE regimen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2HRZE3/6HE regimen (thrice-weekly direct dosing in the intensive phase and once-weekly with six doses self-administered in the continuation phase)
Trial: 15248627
Drug: Ibuprofen 800
RxNorm normalized name: ibuprofen 800 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ibuprofen 800 mg orally 1 h before operation and again at 6 and 12 h after the initial dose.
Trial: 15248627
Drug: Acetaminophen 1
RxNorm normalized name: acetaminophen 15 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acetaminophen 1 g orally at the same time intervals as ibuprofen.
Trial: 15248627
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of ibuprofen 800 mg and acetaminophen 1 g.
Trial: 15248627
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (Acetaminophen group).
Trial: 9030833
Drug: Vitamin D
RxNorm normalized name: Vitamin D
DrugBank: Vitamin D (DB11094)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin D receptor genotype
Trial: 8315263
Drug: Torasemide (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Torasemide (20 mg)
Trial: 3548346
Drug: Fresh frozen
RxNorm normalized name: Fresh frozen plasma
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fresh frozen plasma infusion
Trial: 3548346
Drug: Stored plasma
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Stored plasma infusion
Trial: 3548346
Drug: Daily infusion
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Daily infusion of 1,000 ml of fresh frozen plasma for 7 to 18 days
Trial: 28162769
Drug: Cord blood
RxNorm normalized name: CORD BLOOD
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cord blood granulocyte-colony stimulating factor (G-CSF)
Trial: 28162769
Drug: Receiver operator
RxNorm normalized name: Chem-Star Recover
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Receiver operator curve analysis for G-CSF
Trial: 20008210
Drug: Statin medications
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Statin medications
Trial: 15266759
Drug: Vaginal sildenafil
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vaginal sildenafil (25 mg four times daily intravaginally)
Trial: 7728133
Drug: FTBI/VP-16 regimen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: FTBI/VP-16 regimen with added CY 60 mg/kg
Trial: 26650152
Drug: Permethrin group
RxNorm normalized name: Permethrin
DrugBank: Permethrin (DB04930)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Permethrin group (mass administration of permethrin)
Trial: 26650152
Drug: Ivermectin group
RxNorm normalized name: Ivermectin
DrugBank: Ivermectin (DB00602)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Ivermectin group (mass administration of ivermectin)
Trial: 15003080
Drug: Paroxetine +
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paroxetine + Clonazepam (1.0 to 2.0 mg/day, divided b.i.d.)
Trial: 11762415
Drug: Zevalin (ibritumomab
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Zevalin (ibritumomab tiuxetan) at a dose of 0.4 mCi/kg for patients with platelet counts > 150,000 and < 25% bone marrow involvement; 0.3 mCi/kg for patients with platelet counts between 100,000-149,000.
Trial: 11762415
Drug: Rituximab at
RxNorm normalized name: Rituximab
DrugBank: Rituximab (DB00073)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Rituximab at a standard dose of 375 mg/m2 weekly for four weeks (control group).
Trial: 11762415
Drug: Phase II
RxNorm normalized name: Coxiella burnetii phase II Ab
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Phase II study of reduced dose of Zevalin in patients with mild thrombocytopenia.
Trial: 9327113
Drug: Marezine (50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Marezine (50 mg)
Trial: 9327113
Drug: Dramamine (50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dramamine (50 mg)
Trial: 2564563
Drug: Fluconazole 50
RxNorm normalized name: fluconazole 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fluconazole 50 mg daily
Trial: 25409592
Drug: Hydrocortisone (160
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hydrocortisone (160 mg/day)
Trial: 12590012
Drug: Low-dose hormonal
RxNorm normalized name: Parathyroid Hormone
DrugBank: Parathyroid hormone (DB05829)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Low-dose hormonal replacement therapy (LD‐HRT), 17beta‐estradiol (1 mg/day) and norethisterone acetate (0.5 mg/day)
Trial: 12590012
Drug: Calcium supplement
RxNorm normalized name: Calcium supplement
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Calcium supplement (controls)
Trial: 31411779
Drug: Randomised treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Randomised treatment
Trial: 6756936
Drug: Paracetamol 500
RxNorm normalized name: Paracetamol 500 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paracetamol 500 mg plus codeine 20 mg
Trial: 6756936
Drug: Paracetamol 500
RxNorm normalized name: Paracetamol 500 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paracetamol 500 mg plus codeine 40 mg
Trial: 28736511
Drug: MSM (OptiMSM®)
DrugBank: Dimethyl sulfone (DB14090)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MSM (OptiMSM®) at 3 g/day for 21 days prior to the race and for two days after (23 total)
Trial: 21942465
Drug: Etodolac 400
RxNorm normalized name: etodolac 400 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Etodolac 400 mg twice a day
Trial: 21942465
Drug: Diclofenac 75
RxNorm normalized name: CAPSAICIN 0.025%/DICLOFENAC 75MG KIT
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Diclofenac 75 mg thrice a day
Trial: 12829141
Drug: Postoperative RT
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Postoperative RT combined with mitomycin C (15 mg/m2 after 10 Gy) and bleomycin (5 mg twice a week during RT to a total of 70 mg)
Trial: 10817348
Drug: Epirubicin (120
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Epirubicin (120 mg/m2, i.v. bolus every 3 weeks)
Trial: 8664976
Drug: Growth hormone
RxNorm normalized name: Growth hormone
DrugBank: Somatotropin (DB00052)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Growth hormone (GH) alone (2 IU m‐2 sc q.i.d.)
Trial: 2052337
Drug: Cephalexin, 250
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cephalexin, 250 mg four times a day
Trial: 6619055
Drug: Piperacillin (300
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Piperacillin (300 mg/kg/day) alone