AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 782888
Drug: Hyperbaric oxygenation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hyperbaric oxygenation (OHP) administered at 2.5 ATA in one or several series of daily exposure.
Trial: 782888
Drug: Standard therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Standard therapy (control group).
Trial: 25076759
Drug: Cytoflavin included
RxNorm normalized name: tobramycin
DrugBank: Tobramycin (DB00684)
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: Cytoflavin included in intensive care (administered intravenously at a speed of 140 drops (7 ml) per minute within 7 days, starting from the second day post-injury).
Trial: 15352968
Drug: Rofecoxib 50
RxNorm normalized name: rofecoxib 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Rofecoxib 50 mg po 1 h prior to surgery
Trial: 15352968
Drug: Control (Placebo)
RxNorm normalized name: Afeditab CR
DrugBank: Chloroxylenol (DB11121)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Control (Placebo) + Ketoprofen 100 mg IV q 8 h for 24 h
Trial: 8115195
Drug: 1 mg/kg
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1 mg/kg meperidine
Trial: 3136636
Drug: Class IC
RxNorm normalized name: Antiarrhythmics, class Ic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Class IC agents (overall)
Trial: 793706
Drug: Azathioprine, 2.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Azathioprine, 2.5 mg/kg-d
Trial: 21784378
Drug: Ezetimibe 10
RxNorm normalized name: ezetimibe 10 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ezetimibe 10 mg added to Simvastatin 40 mg (E/S40)
Trial: 21784378
Drug: Atorvastatin 40
RxNorm normalized name: atorvastatin 40 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Atorvastatin 40 mg (A)
Trial: 21784378
Drug: Rosuvastatin 5-10
RxNorm normalized name: rosuvastatin 10 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Rosuvastatin 5-10 mg (R)
Trial: 17507190
Drug: Sustained-release nifedipine
RxNorm normalized name: nifedipine Extended Release Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sustained-release nifedipine tablets from DiSha (test)
Trial: 17507190
Drug: Sustained-release nifedipine
RxNorm normalized name: nifedipine Extended Release Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sustained-release nifedipine tablets from GuoFeng (reference)
Trial: 10024902
Drug: Continuous combined
RxNorm normalized name: Ivy Dry Super Continuous Spray
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Continuous combined HRT (2 mg 17 beta‐estradiol and 1 mg norethisterone acetate administered once daily without estriol)
Trial: 8002124
Drug: GP/PL mixture
FDA approved: no
EMA approved: no
PMDA approved: no
Description: GP/PL mixture (6.25 g GP to 0.75 g PL per 100 ml of water)
Trial: 8002124
Drug: Glucose polymer
RxNorm normalized name: glucose polymers
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Glucose polymer solution (GP)
Trial: 30498758
Drug: Curene 500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Curene 500 mg once daily
Trial: 27465859
Drug: Aspirin users
RxNorm normalized name: Aspirin
DrugBank: Acetylsalicylic acid (DB00945)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Aspirin users (32 patients)
Trial: 18630533
Drug: Acupuncture combined
RxNorm normalized name: combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Acupuncture combined with western medicine (acupuncture at specific points, intramuscular injection of Vit B1 and Vit B12, oral administration of ATP)
Trial: 16046716
Drug: Lyophilized grape
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lyophilized grape powder (LGP) 36 g for 4 weeks
Trial: 12360108
Drug: Pranlukast (225
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pranlukast (225 mg twice daily)
Trial: 12360108
Drug: Inhaled beta-agonist
RxNorm normalized name: Beta Carotene
DrugBank: Beta carotene (DB06755)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhaled beta-agonist salbutamol (200 microg)
Trial: 6148572
Drug: Vaccine aerosol
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vaccine aerosol given by mask at a dose of 3500 or 7000 PFU
Trial: 6148572
Drug: Vaccine aerosol
RxNorm normalized name: Pertussis vaccine
DrugBank: Pertussis vaccine (DB15274)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vaccine aerosol given from a plastic bag at a dose of 7000 PFU
Trial: 6148572
Drug: 11 400
RxNorm normalized name: Interleukin 11
DrugBank: Oprelvekin (DB00038)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: 11 400 PFU of vaccine intradermally in two divided doses
Trial: 30196837
Drug: Interferon-beta (IFNB)
RxNorm normalized name: interferon-beta
DrugBank: Human interferon beta (DB14999)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Interferon-beta (IFNB) treatment
Trial: 30196837
Drug: No immunomodulatory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No immunomodulatory treatment
Trial: 24362488
Drug: Ponesimod (40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ponesimod (40 mg) with combined oral contraceptive (1 mg norethisterone and 35 μg ethinyl estradiol)
Trial: 24362488
Drug: Ponesimod (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ponesimod (20 mg)
Trial: 24362488
Drug: Ponesimod (40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ponesimod (40 mg)
Trial: 11857045
Drug: MCT/LCT (50/50)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MCT/LCT (50/50) supplemented with 100 mg DL-alpha-tocopherol/day
Trial: 10404024
Drug: Hormone replacement
RxNorm normalized name: Parathyroid Hormone
DrugBank: Parathyroid hormone (DB05829)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Hormone replacement therapy (HRT) (cyclic estradiol/norethisterone acetate)
Trial: 7564082
Drug: OPC‐31260 (1
FDA approved: no
EMA approved: no
PMDA approved: no
Description: OPC‐31260 (1 mg/kg body wt)
Trial: 7564082
Drug: OPC‐31260 (low
FDA approved: no
EMA approved: no
PMDA approved: no
Description: OPC‐31260 (low dose unspecified)
Trial: 2188795
Drug: 150 mg
RxNorm normalized name: pectin 150 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 150 mg trazodone at night
Trial: 2188795
Drug: 75 mg
RxNorm normalized name: talc 75 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 75 mg dothiepin at night
Trial: 6996149
Drug: Isopyrine 240
RxNorm normalized name: tisopurine
DrugBank: Tisopurine (DB13807)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Isopyrine 240 mg plus phenylbutazone 130 mg (Tomanol)
Trial: 28633773
Drug: Low-level laser
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-level laser therapy (LLLT) - 15 sessions (8 J/cm2; 830 nm)
Trial: 28633773
Drug: Extracorporeal shock
RxNorm normalized name: ethanol
DrugBank: Ethanol (DB00898)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Extracorporeal shock wave therapy (ESWT) - 3 sessions (2000 shocks)
Trial: 28633773
Drug: Therapeutic ultrasound
RxNorm normalized name: Moisturel Therapeutic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Therapeutic ultrasound (US) therapy - 15 sessions (1 mHz; 2 W/cm2)
Trial: 21813443
Drug: 3 mL
RxNorm normalized name: WATER,INHL 3 ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 mL of PRP
Trial: 21813443
Drug: 3 mL
RxNorm normalized name: WATER,INHL 3 ML
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3 mL of autologous blood
Trial: 17538085
Drug: Surgical treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Surgical treatment (decompressive laminectomy with or without fusion)
Trial: 17538085
Drug: Nonsurgical treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nonsurgical treatment (usual nonsurgical care)
Trial: 11431663
Drug: Dofetilide 500
RxNorm normalized name: DOFETILIDE 500MCG CAP
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dofetilide 500 microg twice daily
Trial: 11431663
Drug: Propafenone 150
RxNorm normalized name: propafenone 150 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Propafenone 150 mg three times a day
Trial: 9529685
Drug: Oral terbinafine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral terbinafine 250 mg daily for 12 weeks
Trial: 2018012
Drug: Metoprolol CR,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metoprolol CR, 200 mg once daily
Trial: 2018012
Drug: Nifedipine retard
RxNorm normalized name: Nifedipine
DrugBank: Nifedipine (DB01115)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Nifedipine retard 20 mg twice daily
Trial: 31089856
Drug: Productive failure
RxNorm normalized name: INVESTIGATIONAL CONGESTIVE HEART FAILURE
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Productive failure (attempt to generate solutions before receiving instruction)
Trial: 19284108
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of magnetopuncture and phytoaeroionotherapeutic chronocorrection
Trial: 19284108
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of soft‐tissue manual therapy
Trial: 17547587
Drug: Quetiapine (600
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Quetiapine (600 and 300 mg/day)
Trial: 14999693
Drug: Prophylactic antibiotics
RxNorm normalized name: polylactic acid-polyglycolic acid copolymer
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Prophylactic antibiotics (ofloxacin 200 mg i.v. q12h for 2 days followed by oral ofloxacin 200 mg q12h for 5 days)
Trial: 14999693
Drug: On-demand antibiotics
RxNorm normalized name: Gel-One
FDA approved: no
EMA approved: no
PMDA approved: no
Description: On-demand antibiotics
Trial: 8461240
Drug: Sustained-release ibuprofen
RxNorm normalized name: ibuprofen Extended Release Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sustained-release ibuprofen (once-daily dosing)
Trial: 8461240
Drug: Conventional-release ibuprofen
RxNorm normalized name: ibuprofen Extended Release Oral Tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional-release ibuprofen (400 mg four times daily)
Trial: 28335697
Drug: Individually tailored
RxNorm normalized name: chloroxylenol
DrugBank: Chloroxylenol (DB11121)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Individually tailored cognitive-behavioral therapy program
Trial: 22962239
Drug: Deworming tablet
RxNorm normalized name: oxfendazole
DrugBank: Oxfendazole (DB11446)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Deworming tablet (400 mg albendazole) once in six months
Trial: 22962239
Drug: Deworming tablet
RxNorm normalized name: oxfendazole
DrugBank: Oxfendazole (DB11446)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Deworming tablet (400 mg albendazole) plus weekly Iron-Folic acid (60 mg elemental iron and 0.5 mg folic acid)
Trial: 1812477
Drug: Theophylline retard
RxNorm normalized name: Theophylline
DrugBank: Theophylline (DB00277)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Theophylline retard preparation administered once daily in addition to baseline medication
Trial: 30417636
Drug: SQ HDM
FDA approved: no
EMA approved: no
PMDA approved: no
Description: SQ HDM SLIT-tablet (ACARIZAX®) as add-on to pharmacotherapy
Trial: 27339453
Drug: Resveratrol (500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Resveratrol (500 mg capsules, twice daily for 4 weeks)
Trial: 27339453
Drug: Placebo (500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (500 mg neutral microcellulose capsules, twice daily for 4 weeks)
Trial: 23066166
Drug: Combined B-vitamin
RxNorm normalized name: VITAMIN B
DrugBank: Inositol (DB13178)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Combined B-vitamin treatment (folic acid 2.5mg, vitamin B(6) 50mg, vitamin B(12) 1mg)
Trial: 23066166
Drug: Combined B-vitamin
RxNorm normalized name: VITAMIN B
DrugBank: Inositol (DB13178)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Combined B-vitamin treatment
Trial: 16276166
Drug: Low-dose hydrocortisone
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose hydrocortisone (50-mg bolus followed by a continuous infusion of 0.18 mg/kg body weight/hr, reduced to 0.06 mg/kg/hr after shock reversal)
Trial: 11924224
Drug: Chewing sugar-free
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Chewing sugar-free gum (sorbitol-sweetened), 1 stick for 15-20 minutes after meals, three times daily
Trial: 9701189
Drug: Tomato-based juice
RxNorm normalized name: tomato juice
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tomato-based juice supplemented with vitamin C (600 mg), vitamin E (400 IU), and beta-carotene (30 mg)
Trial: 2528221
Drug: Metronidazole 1%
RxNorm normalized name: METRONIDAZOLE 1% GEL,TOP
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metronidazole 1% cream applied twice daily
Trial: 17374331
Drug: Methotrexate therapy
RxNorm normalized name: Methotrexate
DrugBank: Methotrexate (DB00563)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Methotrexate therapy
Trial: 1182676
Drug: Methotrexate in
RxNorm normalized name: methotrexate Injection
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Methotrexate in combination with other drugs
Trial: 26119672
Drug: Neoadjuvant chemotherapy
RxNorm normalized name: menthol
DrugBank: Menthol (DB14123)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Neoadjuvant chemotherapy with negative emmprin expression
Trial: 15644672
Drug: Early Parenteral
RxNorm normalized name: benzyl alcohol
DrugBank: Benzyl alcohol (DB06770)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Early Parenteral Nutrition (PN)
Trial: 8748367
Drug: i.v. nutrition
FDA approved: no
EMA approved: no
PMDA approved: no
Description: i.v. nutrition plus triple therapy (heparin, hydrocortisone, glyceryl trinitrate patch)
Trial: 6795122
Drug: O-acetyl-negative polysaccharide
RxNorm normalized name: O-acetyl-L-carnitine
DrugBank: Acetylcarnitine (DB08842)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: O-acetyl-negative polysaccharide vaccine
Trial: 6795122
Drug: O-acetyl-positive polysaccharide
RxNorm normalized name: O-acetyl-L-carnitine
DrugBank: Acetylcarnitine (DB08842)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: O-acetyl-positive polysaccharide vaccine
Trial: 29890569
Drug: Sitagliptin 50
RxNorm normalized name: SITagliptin 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sitagliptin 50 mg daily plus placebo
Trial: 29890569
Drug: Sitagliptin 50
RxNorm normalized name: SITagliptin 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sitagliptin 50 mg daily plus synbiotic
Trial: 8757085
Drug: Poplar bud
RxNorm normalized name: Clove buds
DrugBank: Clove (DB10672)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Poplar bud ointment saturated with trace metal elements
Trial: 1722835
Drug: Ointments with
RxNorm normalized name: urea Topical Ointment [Aquaphilic with Urea]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ointments with antibiotics and antiseptics on a fat base (Control)
Trial: 17157339
Drug: 10-steroid profile
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 10-steroid profile measured by tandem mass spectrometry during high dose cortrosyn stimulation test
Trial: 17157339
Drug: Three-steroid profile
RxNorm normalized name: three-lobe sage extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Three-steroid profile
Trial: 17157339
Drug: 11-deoxycortisol, dehydroepiandrosterone,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 11-deoxycortisol, dehydroepiandrosterone, and two-steroid profile
Trial: 17157339
Drug: Stimulated levels
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Stimulated levels of aldosterone, 11-deoxycortisol, dehydroepiandrosterone, and two- or three-steroid profile
Trial: 17157339
Drug: Steroid profile
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Steroid profile measuring cortisol, aldosterone, 11-deoxycortisol, and dehydroepiandrosterone
Trial: 15750416
Drug: Low-dose inductive
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose inductive chemotherapy, surgery, and then radiotherapy
Trial: 15750416
Drug: Neoadjuvant cytostatic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Neoadjuvant cytostatic treatment with adequate tissue regression
Trial: 15750416
Drug: Changes in
RxNorm normalized name: guaifenesin / hydrocodone bitartrate Oral Solution [Canges XP]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Changes in expressions of laminin and syndecan-1 in response to cytostatic treatment
Trial: 10617008
Drug: Intraoperative administration
RxNorm normalized name: polidocanol
DrugBank: Polidocanol (DB06811)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intraoperative administration of 3000 IU of antithrombin III (AT III) concentrates plus heparin (Group A)
Trial: 10617008
Drug: Heparin only
RxNorm normalized name: Heparin only product
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Heparin only (Group B)
Trial: 6250928
Drug: Antacid gel
DrugBank: Dimethicone (DB11074)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Antacid gel (magnesium and aluminium hydroxide)
Trial: 27820728
Drug: 100-times stretching
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100-times stretching treatment
Trial: 27820728
Drug: 50-times stretching
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 50-times stretching treatment
Trial: 22403970
Drug: Prophylactic inhalation
RxNorm normalized name: polylactic acid-polyglycolic acid copolymer
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Prophylactic inhalation of isopropyl alcohol (IPA) vapors with IV ondansetron
Trial: 17524288
Drug: OraSure oral
RxNorm normalized name: benzalkonium
DrugBank: Benzalkonium (DB11105)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: OraSure oral fluid testing
Trial: 7987882
Drug: 5 mg/day
RxNorm normalized name: Lyllana 0.05 MG/Day Transdermal Patch
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg/day simvastatin
Trial: 7987882
Drug: 10 mg/day
RxNorm normalized name: Adlarity 10 MG/Day Weekly Transdermal System
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 10 mg/day simvastatin
Trial: 2547465
Drug: Intravenous doses
RxNorm normalized name: Metered Dose Inhaler
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous doses of lisinopril
Trial: 2547465
Drug: Oral doses
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral doses of lisinopril (10 daily doses, q24h)
Trial: 5302328
Drug: Whole-cell cholera
RxNorm normalized name: cholera, inactivated, whole cell
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Whole-cell cholera vaccine, 0.5 ml dose
Trial: 5302328
Drug: Purified Ogawa
RxNorm normalized name: RAYON,PURIFIED
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Purified Ogawa antigen, 100 mug dose
Trial: 5302328
Drug: Whole-cell cholera
RxNorm normalized name: cholera, inactivated, whole cell
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Whole-cell cholera vaccine, 0.4 ml dose
Trial: 5302328
Drug: Whole-cell cholera
RxNorm normalized name: cholera, inactivated, whole cell
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Whole-cell cholera vaccine
Trial: 29151315
Drug: 200 mg/day
RxNorm normalized name: alpelisib 200 mg/day (200 mg x 1) ORAL TABLET
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 200 mg/day oral iron for 3 months
Trial: 29151315
Drug: Oral placebo
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral placebo for 3 months
Trial: 23680766
Drug: agalsidase alfa
RxNorm normalized name: Agalsidase alfa
DrugBank: Agalsidase alfa (DB15874)
FDA approved: no
EMA approved: yes
PMDA approved: no
Description: agalsidase alfa (0.2 mg/kg every other week for 12 months)
Trial: 22012809
Drug: Intravenous infusion
RxNorm normalized name: intravenous infusion pump accessory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous infusion of tranexamic acid (loading dose of 500 mg before surgery followed by continuous infusion of 250 mg/h during surgery)
Trial: 22012809
Drug: Intravenous infusion
RxNorm normalized name: intravenous infusion pump accessory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous infusion of tranexamic acid
Trial: 22012809
Drug: Intravenous infusion
RxNorm normalized name: intravenous infusion pump accessory
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous infusion of tranexamic acid and placebo
Trial: 19691851
Drug: Artesunate and
RxNorm normalized name: artesunate and mefloquine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Artesunate and amodiaquine fixed dose combination (FDC)
Trial: 19691851
Drug: Artesunate and
RxNorm normalized name: artesunate and mefloquine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Artesunate and amodiaquine given in separate tablets
Trial: 9118699
Drug: L‐5‐hydroxytryptophan (L‐5‐HTP),
FDA approved: no
EMA approved: no
PMDA approved: no
Description: L‐5‐hydroxytryptophan (L‐5‐HTP), 0.4 mg/kg
Trial: 28581398
Drug: Dose-escalated external
RxNorm normalized name: CATHETER,EXTERNAL
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dose-escalated external beam (DE‐EBRT) boost
Trial: 28581398
Drug: Low-dose-rate prostate
RxNorm normalized name: Sus scrofa prostate preparation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-dose-rate prostate brachytherapy (LDR‐PB) boost
Trial: 26621252
Drug: Antidepressant medication
RxNorm normalized name: ANTIDEPRESSANTS
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Antidepressant medication at baseline
Trial: 26621252
Drug: Antidepressant medication
RxNorm normalized name: ANTIDEPRESSANTS
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Antidepressant medication at follow up
Trial: 14500473
Drug: One dose
RxNorm normalized name: Next Choice One Dose
DrugBank: Levonorgestrel (DB00367)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: One dose of MCC-TT vaccine
Trial: 14500473
Drug: Two doses
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Two doses of MCC-TT vaccine
Trial: 14500473
Drug: Three doses
RxNorm normalized name: three-lobe sage extract
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Three doses of MCC-TT vaccine
Trial: 1394812
Drug: Intravesical thio-TEPA
RxNorm normalized name: thiotepa
DrugBank: Thiotepa (DB04572)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Intravesical thio-TEPA at 30 mg/30 ml physiological saline, instilled 32 times over 2 years (group T)