AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 20227549
Drug: 200 mg
RxNorm normalized name: RNA 200 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 200 mg of mifepristone followed 48 h later by 400 mcg oral misoprostol (Group 1)
Trial: 20227549
Drug: 800‐mcg intravaginal
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 800‐mcg intravaginal single‐dose misoprostol (Group 2)
Trial: 15656879
Drug: warfarin 1.25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: warfarin 1.25 mg plus aspirin 75 mg daily
Trial: 15656879
Drug: aspirin 75
RxNorm normalized name: aspirin 75 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: aspirin 75 mg alone
Trial: 11893234
Drug: Paroxetine 10
RxNorm normalized name: PARoxetine 10 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paroxetine 10 to 50 mg/day
Trial: 11893234
Drug: Paroxetine 10
RxNorm normalized name: PARoxetine 10 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paroxetine 10 to 40 mg/day
Trial: 11893234
Drug: Paroxetine 20
RxNorm normalized name: PARoxetine 20 mg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paroxetine 20 to 60 mg/day
Trial: 10373134
Drug: Inhaled formoterol
RxNorm normalized name: formoterol Inhalation Solution
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Inhaled formoterol (12 microg twice a day)
Trial: 2230910
Drug: 2 g
RxNorm normalized name: Molds 2 g
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2 g mezlocillin and 200 mg netilmicin as an i.v. bolus before implantation
Trial: 2230910
Drug: 2 g
RxNorm normalized name: Molds 2 g
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2 g mezlocillin before and then 6 and 12 hours after surgery and 200 mg netilmicin before and then 12 hours after implantation
Trial: 26002111
Drug: Primary chemotherapy
RxNorm normalized name: Sodium primary phosphate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Primary chemotherapy (3 cycles followed by surgery and then 3 cycles of completion chemotherapy)
Trial: 26002111
Drug: Primary surgery
RxNorm normalized name: Sodium primary phosphate
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Primary surgery (followed by 6 cycles of chemotherapy)
Trial: 10220541
Drug: Beta blocker
RxNorm normalized name: Beta blocker
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Beta blocker treatment
Trial: 23500609
Drug: No beta
RxNorm normalized name: Amidino beta-alanine
DrugBank: Ompenaclid (DB18819)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No beta blocker treatment
Trial: 19240703
Drug: Low-volume phosphate
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-volume phosphate solution (75 ml)
Trial: 19240703
Drug: Low-volume sulfate
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-volume sulfate solution (equimolar dose)
Trial: 19240703
Drug: PEG (polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PEG (polyethylene glycol) lavage solution (4 liters)
Trial: 15545201
Drug: Increased fluid
RxNorm normalized name: amniotic fluid (bovine)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Increased fluid intake (60 ml/kg body weight per day)
Trial: 15545201
Drug: Normal fluid
RxNorm normalized name: amniotic fluid (bovine)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Normal fluid intake (30 ml/kg body weight per day)
Trial: 11552354
Drug: Exercise therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Exercise therapy (aerobic, dynamic strengthening exercises)
Trial: 2441203
Drug: Captopril (CPT)
RxNorm normalized name: Captopril
DrugBank: Captopril (DB01197)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Captopril (CPT) 25 mg every 8 hours (t.i.d.)
Trial: 2441203
Drug: Digoxin (D)
RxNorm normalized name: Digoxin
DrugBank: Digoxin (DB00390)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Digoxin (D) 0.25 mg once daily
Trial: 29624476
Drug: Novel therapies
RxNorm normalized name: Theraplex Eczema Therapy
DrugBank: Colloidal oatmeal (DB11286)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Novel therapies targeting pro-inflammatory pathways (e.g., IL-12/23 axis, IL-6 pathway, Janus Kinase inhibitors)
Trial: 29624476
Drug: Therapies modulating
RxNorm normalized name: Theraplex Eczema Therapy
DrugBank: Colloidal oatmeal (DB11286)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Therapies modulating anti-inflammatory pathways (e.g., TGF-β1)
Trial: 29624476
Drug: Drugs targeting
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Drugs targeting leukocyte adhesion and migration (e.g., α4β7 integrins, MAdCAM-1)
Trial: 29624476
Drug: Sphingosine-1-phosphate (S1P)
RxNorm normalized name: Sphingosine-1-phosphate (S1P) receptor modulators
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sphingosine-1-phosphate (S1P) receptor modulators
Trial: 29624476
Drug: Cell therapies
RxNorm normalized name: Theraplex Eczema Therapy
DrugBank: Colloidal oatmeal (DB11286)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cell therapies using mesenchymal stem cells or engineered T regs
Trial: 27363734
Drug: Low-level laser
RxNorm normalized name: low-density polyethylene
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Low-level laser therapy (InGaAIP laser, 660 nanometer, 40 milliwatts of power, 5 Joules per square centimeter of energy density for 5 seconds each, total energy = 0.6 Joules)
Trial: 11973012
Drug: Lamotrigine (maximum
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lamotrigine (maximum dose of 400 mg)
Trial: 10403341
Drug: PM‐YF vaccine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PM‐YF vaccine
Trial: 10403341
Drug: W‐YF vaccine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: W‐YF vaccine (Arilvax)
Trial: 2044332
Drug: Flumazenil 10
RxNorm normalized name: flumazenil 100 % MISCELL POWDER (GRAM)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Flumazenil 10 mg intravenously
Trial: 7016300
Drug: BCG treatment
RxNorm normalized name: Tice BCG
DrugBank: Bacillus calmette-guerin substrain tice live antigen (DB10343)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: BCG treatment (120 mg intravesically and 5 mg percutaneously, six weekly administrations)
Trial: 27683798
Drug: Increased dosing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Increased dosing frequency from every 8 weeks to every 4 weeks
Trial: 26072416
Drug: Pexa-Vec (JX-594)
RxNorm normalized name: B-VEC
DrugBank: Beremagene geperpavec (DB17831)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pexa-Vec (JX-594) administered by intratumoral injection at a dose of 1 × 10(8) pfu
Trial: 26072416
Drug: Pexa-Vec (JX-594)
RxNorm normalized name: B-VEC
DrugBank: Beremagene geperpavec (DB17831)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pexa-Vec (JX-594) administered by intratumoral injection at a dose of 1 × 10(9) pfu
Trial: 12663290
Drug: Black tea
RxNorm normalized name: black tea
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Black tea (1250 mL/d, 5 cups each containing 2 g tea leaves in 250 mL boiled water)
Trial: 12663290
Drug: Hot water
RxNorm normalized name: hot water bottle
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hot water (1250 mL/d)
Trial: 10859453
Drug: Morphine plus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Morphine plus MLT (20 mg/day orally in the evening)
Trial: 10859453
Drug: Morphine plus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Morphine plus MLT
Trial: 6360110
Drug: 3% acyclovir
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3% acyclovir ointment five times a day in combination with alpha-interferon (30 million IU/mL)
Trial: 6360110
Drug: 3% acyclovir
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 3% acyclovir ointment five times a day
Trial: 27923864
Drug: Harm Reduction
RxNorm normalized name: reductic acid
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Harm Reduction (HR; eight contacts over 12 months with medication use)
Trial: 27923864
Drug: Intensive Treatment
RxNorm normalized name: Uricalm Intensive
DrugBank: Acetylsalicylic acid (DB00945)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intensive Treatment (IT; six contacts over 6 months)
Trial: 20524974
Drug: Testosterone undecanoate
RxNorm normalized name: Testosterone Undecanoate
DrugBank: Testosterone undecanoate (DB13946)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Testosterone undecanoate (TU; 1,000 mg IM at baseline, and after 6 and 18 weeks)
Trial: 7823995
Drug: Once-daily trial
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Once-daily trial of spontaneous breathing
Trial: 2079566
Drug: All treatment
RxNorm normalized name: UNDECYLENIC ACID 8 g in 30 mL / TOLNAFTATE 1 g in 30 mL TOPICAL LIQUID [Fugal nall treatment]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: All treatment responders (Groups A, B, C)
Trial: 90270
Drug: 100 mg
RxNorm normalized name: urea 100 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 100 mg BAY g 5421 before a 50 g sucrose meal
Trial: 25712847
Drug: Chest tube
RxNorm normalized name: Kids-Eeze Chest Relief
DrugBank: Guaifenesin (DB00874)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Chest tube removal when drainage volume <100 ml/day (Control Group - CG)
Trial: 21692283
Drug: Combined therapy
RxNorm normalized name: REGN10933+REGN10987 combination therapy
DrugBank: Anti-SARS-CoV-2 REGN-COV2 (DB15691)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combined therapy of electroacupuncture and acupoint injection
Trial: 10731289
Drug: Enoxaparin and
RxNorm normalized name: enoxaparin
DrugBank: Enoxaparin (DB01225)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Enoxaparin and abciximab administration during percutaneous coronary intervention
Trial: 10731289
Drug: Abciximab administration
RxNorm normalized name: Abciximab
DrugBank: Abciximab (DB00054)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Abciximab administration
Trial: 1571752
Drug: Clomipramine (100-200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Clomipramine (100-200 mg/day)
Trial: 3883503
Drug: Megestrol acetate
RxNorm normalized name: Megestrol Acetate
DrugBank: Megestrol (DB19378)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Megestrol acetate 40 mg orally, four times daily
Trial: 3883503
Drug: Tamoxifen 10
RxNorm normalized name: tamoxifen 10 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tamoxifen 10 mg orally twice daily
Trial: 25486294
Drug: β-alanine (BA)
RxNorm normalized name: Alanine
DrugBank: Alanine (DB00160)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: β-alanine (BA) supplementation (3.4 g)
Trial: 25486294
Drug: Placebo (PL;
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (PL; 5 g maltodextrin)
Trial: 22963388
Drug: Oriental Medicine
RxNorm normalized name: Medicaine Sting
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oriental Medicine Music Therapy (OMMT)
Trial: 22963388
Drug: Control Music
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control Music Therapy (CMT)
Trial: 21054464
Drug: Omeprazole, Amoxicillin,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Omeprazole, Amoxicillin, and Clarithromycin (OAC)
Trial: 24921211
Drug: Rabeprazole, Amoxicillin,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Rabeprazole, Amoxicillin, and Clarithromycin (RAC)
Trial: 12160664
Drug: Remacemide hydrochloride
RxNorm normalized name: Chlorpromazine Hydrochloride
DrugBank: Remacemide (DB06458)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Remacemide hydrochloride (up to 600 mg daily)
Trial: 9622282
Drug: Metoprolol (100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metoprolol (100 mg o.d.)
Trial: 8352673
Drug: Captopril (12.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Captopril (12.5 mg)
Trial: 29621293
Drug: Apomorphine (1.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Apomorphine (1.5 mg subcutaneous injection)
Trial: 27164988
Drug: Transhiatal approach
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Transhiatal approach and D2 total gastrectomy after neoadjuvant chemotherapy (NAC) for AEG patients
Trial: 27164988
Drug: D2 gastrectomy
RxNorm normalized name: vitamin D2
DrugBank: Ergocalciferol (DB00153)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: D2 gastrectomy after neoadjuvant chemotherapy (NAC) for non-AEG patients
Trial: 26222764
Drug: Neoadjuvant systemic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Neoadjuvant systemic therapy (NST) including neoadjuvant paclitaxel ± carboplatin ± bevacizumab followed by doxorubicin plus cyclophosphamide ± bevacizumab
Trial: 21048092
Drug: Dopexamine (0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dopexamine (0.5 μg · kg(‐1) · min(‐1))
Trial: 17010742
Drug: 1 mg/L
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1 mg/L methoxsalen
Trial: 17010742
Drug: 5 mg/L
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg/L methoxsalen
Trial: 14740594
Drug: 5 mg
RxNorm normalized name: talc 25 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg bupivacaine 0.1% mixed with 20 micrograms fentanyl
Trial: 14740594
Drug: 5 mg
RxNorm normalized name: talc 25 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 mg bupivacaine 0.1%
Trial: 19390752
Drug: Megestrol acetate
RxNorm normalized name: Megestrol Acetate
DrugBank: Megestrol (DB19378)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Megestrol acetate (MA) 800 mg/day
Trial: 1441877
Drug: 20 ml
RxNorm normalized name: Exact-Med, 20 mL
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 20 ml of 2.2% lidocaine hydrocarbonate with 5 micrograms.ml‐1 epinephrine (Group CO2 = 13 patients)
Trial: 1441877
Drug: 20 ml
RxNorm normalized name: Exact-Med, 20 mL
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 20 ml of 2% lidocaine hydrochloride with 5 micrograms.ml‐1 epinephrine (HCl group)
Trial: 27515885
Drug: Kuan-Sin-Yin (KSY)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Kuan-Sin-Yin (KSY) herbal decoction, 100 mL daily for 6 weeks
Trial: 27515885
Drug: Placebo herbal
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo herbal decoction, 100 mL daily for 6 weeks
Trial: 14688492
Drug: Pravastatin (40
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pravastatin (40 mg daily)
Trial: 9296940
Drug: Intravenous Augmentin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous Augmentin 1.2 g
Trial: 2691484
Drug: Control (no
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control (no antibiotic)
Trial: 8282140
Drug: Estriol (8
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Estriol (8 mg/day first week, 4 mg/day second and third week, 2 mg/day fourth week)
Trial: 20406589
Drug: Coseasonal therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Coseasonal therapy with 5000 AU/week for 6 weeks
Trial: 20406589
Drug: Precoseasonal therapy
RxNorm normalized name: Monistat Simple Therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Precoseasonal therapy with 3000 AU/week for 10 weeks
Trial: 15708385
Drug: Albendazole (400
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Albendazole (400 mg, two doses six months apart)
Trial: 12592272
Drug: Misoprostol 50
RxNorm normalized name: diclofenac-misoprostol 50 mg-200 mcg oral tablet
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Misoprostol 50 microg every 6 hours for two doses
Trial: 12592272
Drug: Dinoprostone insert
RxNorm normalized name: dinoprostone Vaginal Insert
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dinoprostone insert 10 mg for one dose intravaginally
Trial: 12592272
Drug: Dinoprostone gel
RxNorm normalized name: Dinoprostone
DrugBank: Dinoprostone (DB00917)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Dinoprostone gel 0.5 mg every 6 hours for two doses
Trial: 17889983
Drug: Dinoprostone gel
RxNorm normalized name: Dinoprostone
DrugBank: Dinoprostone (DB00917)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Dinoprostone gel
Trial: 10495374
Drug: Finasteride 0.01
RxNorm normalized name: ALFATRADIOL 0.05 g in 100 g / MINOXIDIL SULFATE ESTER 12 g in 100 g / FINASTERIDE 0.01 g in 100 g TOPICAL LIQUID [NR-11]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Finasteride 0.01 mg
Trial: 10495374
Drug: Finasteride 0.05
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Finasteride 0.05 mg
Trial: 15319158
Drug: Finasteride 1
RxNorm normalized name: finasteride 1 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Finasteride 1 mg
Trial: 31065046
Drug: Adjustment for
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Adjustment for homeostasis model assessment of insulin resistance
Trial: 23860105
Drug: Padma Digestin
RxNorm normalized name: Padma Flower
DrugBank: Nelumbo nucifera flower (DB14333)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Padma Digestin (2 × 3 capsules daily for 6 weeks)
Trial: 21865569
Drug: 2 servings
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2 servings of vegetables (130 g)
Trial: 21865569
Drug: 5 servings
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 5 servings of vegetables (287 g)
Trial: 21865569
Drug: 10 servings
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 10 servings of vegetables (614 g)
Trial: 21865569
Drug: All doses
RxNorm normalized name: All Clear
DrugBank: Ethanol (DB00898)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: All doses of vegetables
Trial: 19967149
Drug: Simvastatin 40
RxNorm normalized name: simvastatin 40 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Simvastatin 40 mg/day (n = 28)
Trial: 11113085
Drug: Pentoxifylline (PTX)
RxNorm normalized name: Pentoxifylline
DrugBank: Pentoxifylline (DB00806)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Pentoxifylline (PTX) 400 mg orally 3 times daily
Trial: 1549966
Drug: Diltiazem CD
RxNorm normalized name: Diltiazem Hydrochloride 300 MG Oral Capsule, Extended Release, 24 HR [DILTIAZEM CD]
DrugBank: Diltiazem (DB00343)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Diltiazem CD 90 mg
Trial: 1549966
Drug: Diltiazem CD
RxNorm normalized name: Diltiazem Hydrochloride 300 MG Oral Capsule, Extended Release, 24 HR [DILTIAZEM CD]
DrugBank: Diltiazem (DB00343)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Diltiazem CD 180 mg
Trial: 1549966
Drug: Diltiazem CD
RxNorm normalized name: Diltiazem Hydrochloride 300 MG Oral Capsule, Extended Release, 24 HR [DILTIAZEM CD]
DrugBank: Diltiazem (DB00343)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Diltiazem CD 360 mg
Trial: 1549966
Drug: Diltiazem CD
RxNorm normalized name: Diltiazem Hydrochloride 300 MG Oral Capsule, Extended Release, 24 HR [DILTIAZEM CD]
DrugBank: Diltiazem (DB00343)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Diltiazem CD 540 mg
Trial: 2421976
Drug: Dextran 70
RxNorm normalized name: Dextran 70
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dextran 70 (0.5 L)
Trial: 22659533
Drug: Add-on ezetimibe
RxNorm normalized name: Ezetimibe
DrugBank: Ezetimibe (DB00973)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Add-on ezetimibe (10 mg/day)
Trial: 22659533
Drug: Double-dose pravastatin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Double-dose pravastatin
Trial: 18589030
Drug: Algal-oil capsules
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Algal-oil capsules (600 mg DHA/day)
Trial: 14607455
Drug: Vitamin C
RxNorm normalized name: Vitamin C
DrugBank: Sodium ascorbate (DB14482)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin C (24 mg/min)
Trial: 11796586
Drug: Monovalent meningococcal
RxNorm normalized name: MENINGOCOCCAL B
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Monovalent meningococcal B OMV vaccine
Trial: 10320158
Drug: Intravenous lactated
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous lactated Ringer's solution (LR)
Trial: 8916607
Drug: Increase fluid
RxNorm normalized name: amniotic fluid (bovine)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Increase fluid intake by 500 cc
Trial: 8916607
Drug: Decrease fluid
RxNorm normalized name: amniotic fluid (bovine)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Decrease fluid intake by 300 cc
Trial: 1790544
Drug: Nitrendipine 20
RxNorm normalized name: nitrendipine 20 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Nitrendipine 20 mg daily for 60 days
Trial: 6125089
Drug: Alprazolam (0.75
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Alprazolam (0.75 mg to 3 mg per day, average final dose: 1.59 mg)
Trial: 6125089
Drug: Lorazepam (3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Lorazepam (3 mg to 12 mg per day, average final dose: 5.97 mg)
Trial: 17727574
Drug: Combination therapies
RxNorm normalized name: REGN10933+REGN10987 combination therapy
DrugBank: Anti-SARS-CoV-2 REGN-COV2 (DB15691)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination therapies for refractory cases of NE
Trial: 9699022
Drug: Selenium-enriched yeast
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Selenium-enriched yeast supplementation (4.8 mg yeast containing 5 microgram selenium daily via naso-gastric drip for 14 days)
Trial: 2506874
Drug: Intralipid 20%
RxNorm normalized name: Intralipid 20% Fat Emulsion for Injection
DrugBank: Soybean oil (DB09422)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intralipid 20% administered to ten infants
Trial: 2506874
Drug: Sunflower seed
RxNorm normalized name: SUNFLOWER SEED
DrugBank: Sunflower seed (DB10907)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sunflower seed oil rubbed six times daily on the skin of nine infants
Trial: 2506874
Drug: Intralipid administered
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intralipid administered to four patients who had previously received sunflower seed oil
Trial: 2506874
Drug: Topical application
RxNorm normalized name: Talc Topical application Powder
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical application of sunflower seed oil
Trial: 30094626
Drug: Commonly recommended
RxNorm normalized name: Common carp
DrugBank: Common carp (DB10614)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Commonly recommended dosing of omeprazole
Trial: 30094626
Drug: Suboptimal dosing
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Suboptimal dosing of omeprazole
Trial: 16732144
Drug: Oral prednisolone
RxNorm normalized name: prednisolone Oral Solution
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oral prednisolone (2 mg/kg per day in three divided doses for 3 days)
Trial: 18780503
Drug: Penehyclidine hydrochloride
RxNorm normalized name: Chlorpromazine Hydrochloride
DrugBank: Penequinine, Penehyclidine (DB16287)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Penehyclidine hydrochloride (0.01 mg/kg)