AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Trial: 25632575
Drug: Medication (Aspirin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Medication (Aspirin and Panax Notoginseng Saponins)
Trial: 21730216
Drug: Soy protein
RxNorm normalized name: Soy Protein
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Soy protein intake (median of 30 g/d)
Trial: 17341994
Drug: Olmesartan medoxomil
RxNorm normalized name: Olmesartan Medoxomil
DrugBank: Olmesartan (DB00275)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Olmesartan medoxomil 20 mg, titrated to 40 mg at week 4, remained at 40 mg at week 8 and 12
Trial: 17341994
Drug: Losartan potassium
RxNorm normalized name: Losartan Potassium
DrugBank: Losartan (DB00678)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Losartan potassium 50 mg, titrated to 50 mg twice daily at week 8
Trial: 17341994
Drug: Valsartan 80
RxNorm normalized name: valsartan 80 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Valsartan 80 mg, titrated to 320 mg at week 8
Trial: 15231078
Drug: Iron administered
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Iron administered once a week (60 mg as 300-mg ferrous sulfate tablets)
Trial: 15231078
Drug: Iron administered
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Iron administered twice a week (60 mg as 300-mg ferrous sulfate tablets)
Trial: 15231078
Drug: Iron administered
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Iron administered once a day (60 mg as 300-mg ferrous sulfate tablets)
Trial: 11727882
Drug: Adolescent group
RxNorm normalized name: Streptococcus viridans group
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Adolescent group therapy (AGT)
Trial: 3326115
Drug: Zopiclone 2.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Zopiclone 2.5 mg
Trial: 3326115
Drug: Zopiclone (various
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Zopiclone (various doses)
Trial: 25527295
Drug: Fixed-combination bimatoprost/timolol
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fixed-combination bimatoprost/timolol (bim/tim)
Trial: 25527295
Drug: Fixed-combination dorzolamide/brimonidine/timolol
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fixed-combination dorzolamide/brimonidine/timolol (dorz/brim/tim)
Trial: 22308289
Drug: G-CSF-mobilized peripheral
RxNorm normalized name: G-CSF
DrugBank: Lenograstim (DB13144)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: G-CSF-mobilized peripheral blood mononuclear cells (G-PBMCs)
Trial: 20376496
Drug: Pregabalin 150
RxNorm normalized name: pregabalin 150 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pregabalin 150 mg before surgery and repeated after 12 hours
Trial: 16154698
Drug: 0.15 mg
RxNorm normalized name: iodine 0.15 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.15 mg buprenorphine i.v. and placebo pill s.l.
Trial: 16154698
Drug: 0.2 mg
RxNorm normalized name: niacin 0.2 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.2 mg buprenorphine s.l. and saline 0.9% i.v.
Trial: 16154698
Drug: saline 0.9%
RxNorm normalized name: CVS Saline 0.9% Nasal Mist
FDA approved: no
EMA approved: no
PMDA approved: no
Description: saline 0.9% i.v. and placebo pill s.l.
Trial: 12810244
Drug: Topical application
RxNorm normalized name: Talc Topical application Powder
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topical application of 1% methyl nicotinate (MN)
Trial: 1333087
Drug: Nedocromil sodium
RxNorm normalized name: Nedocromil Sodium
DrugBank: Nedocromil (DB00716)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Nedocromil sodium (4 mg b.d. or q.i.d.)
Trial: 3913424
Drug: Preparation A
RxNorm normalized name: POVIDONE-IODINE 75 mg in 1 mL TOPICAL SOLUTION [Antiseptic Patient Preoperative Skin Preparation and Surgical Hand Scrub]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Preparation A (gastropulgit) - 2 bags
Trial: 3913424
Drug: Preparation B
RxNorm normalized name: cranberry preparation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Preparation B (commercial product) - 2 bags
Trial: 30388596
Drug: Oxandrolone (synthetic
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Oxandrolone (synthetic hormone analog of testosterone)
Trial: 29703749
Drug: Combination of
RxNorm normalized name: combination of rauwolfia alkaloids and diuretics incl. other combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination of MSCs and CPCs
Trial: 20570237
Drug: Combination intravitreal
RxNorm normalized name: Dexamethasone Intravitreal Implant
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination intravitreal ranibizumab 0.5 mg and topically applied MMC (0.4 mg/mL for 2 min)
Trial: 20570237
Drug: Topical MMC
RxNorm normalized name: MMC
DrugBank: Mitomycin (DB00305)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Topical MMC (0.4 mg/mL for 2 min) alone
Trial: 16009446
Drug: No probucol
RxNorm normalized name: Probucol
DrugBank: Probucol (DB01599)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: No probucol treatment
Trial: 10663455
Drug: Intravenous dopamine
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous dopamine infusion (2 microg/kg/min)
Trial: 8860788
Drug: Health promotion
RxNorm normalized name: Healthy Mama
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Health promotion intervention (11 weeks of daily circuit training exercise and health lecture-discussions)
Trial: 1310160
Drug: Radiotherapy combined
RxNorm normalized name: combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Radiotherapy combined with daily cisplatin (6 mg/m² before radiotherapy)
Trial: 1310160
Drug: Radiotherapy combined
RxNorm normalized name: combinations
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Radiotherapy combined with weekly cisplatin (30 mg/m² on the first day of each treatment week)
Trial: 25165427
Drug: 0.075-mg palonosetron
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 0.075-mg palonosetron
Trial: 25165427
Drug: 40-mg aprepitant
RxNorm normalized name: aprepitant 40 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 40-mg aprepitant
Trial: 21717516
Drug: Low-dose (72 mg-ECP/day)
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose (72 mg-ECP/day)
Trial: 21717516
Drug: High-dose (144 mg-ECP/day)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose (144 mg-ECP/day)
Trial: 18473194
Drug: Intravenous (IV)
RxNorm normalized name: intravenous (IV) infusion pump
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Intravenous (IV) iron supplementation
Trial: 18473194
Drug: Erythropoietic Stimulating
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Erythropoietic Stimulating Agents (ESAs)
Trial: 17544845
Drug: (223)Ra (50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: (223)Ra (50 kBq/kg, 4 intravenous injections every 4 weeks)
Trial: 17544845
Drug: Placebo (4
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (4 intravenous injections every 4 weeks)
Trial: 8579030
Drug: Carvedilol (25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Carvedilol (25 mg twice daily)
Trial: 15846279
Drug: Metoprolol tartrate
RxNorm normalized name: Metoprolol Tartrate
DrugBank: Metoprolol (DB00264)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Metoprolol tartrate (50 mg twice daily)
Trial: 25122977
Drug: Marketed stabilized
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Marketed stabilized stannous fluoride (SnF2) dentifrice (Oral‐B Pro‐Expert, 0.454% SnF2 plus 0.077% NaF)
Trial: 9571349
Drug: Fosinopril (20
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Fosinopril (20 mg/day)
Trial: 15059705
Drug: Topical ofloxacin
RxNorm normalized name: Ofloxacin
DrugBank: Ofloxacin (DB01165)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Topical ofloxacin 0.3% applied four times a day for 3 days before surgery and 1 hour preoperatively
Trial: 15059705
Drug: Topical ofloxacin
RxNorm normalized name: Ofloxacin
DrugBank: Ofloxacin (DB01165)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Topical ofloxacin 1 hour before surgery
Trial: 9707165
Drug: Budesonide (inhaled
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Budesonide (inhaled glucocorticoid)
Trial: 2096345
Drug: Iontophoresis of
RxNorm normalized name: OIL OF CAMPHOR
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Iontophoresis of lidocaine hydrochloride 4% solution
Trial: 32798
Drug: Diazepam with
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Diazepam with benzyl alcohol (0.35 mg/kg diazepam, 1.1 mg/kg benzyl alcohol)
Trial: 19825327
Drug: MEL‐OD (test
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MEL‐OD (test formulation)
Trial: 19825327
Drug: Mobic (reference
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Mobic (reference formulation)
Trial: 9286853
Drug: Mibefradil 50
RxNorm normalized name: mibefradil 50 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Mibefradil 50 mg and 100 mg
Trial: 7934778
Drug: Low-dose inhalation
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: Low-dose inhalation
Trial: 7934778
Drug: High-dose inhalation
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High-dose inhalation
Trial: 25633584
Drug: Moxibustion treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Moxibustion treatment before menstruation onset (Group A)
Trial: 25633584
Drug: Moxibustion treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Moxibustion treatment at the onset of menstruation (Group B)
Trial: 24000658
Drug: PCA with
RxNorm normalized name: lauryl PCA
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PCA with trimeperidine in combination with nefopam constant infusion
Trial: 24000658
Drug: PCA with
RxNorm normalized name: lauryl PCA
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PCA with trimeperidine in combination with nefopam bolus
Trial: 18022165
Drug: Metformin (500
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Metformin (500 mg twice per day for 12 weeks)
Trial: 12684147
Drug: ML Cu
RxNorm normalized name: SYRINGE 10-12ML CURVED TIP
FDA approved: no
EMA approved: no
PMDA approved: no
Description: ML Cu 375 sl
Trial: 9211677
Drug: 1 microg
RxNorm normalized name: Alpha 1 microglobulin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 1 microg of ganciclovir per hour implant
Trial: 9211677
Drug: 2 microg
RxNorm normalized name: Beta 2 microglobulin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 2 microg of ganciclovir per hour implant
Trial: 1412113
Drug: Intravenous methylprednisolone
RxNorm normalized name: Methylprednisolone
DrugBank: Methylprednisolone (DB00959)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intravenous methylprednisolone 10 mg/kg every four hours for 48 hours (group A)
Trial: 1412113
Drug: Intravenous methylprednisolone
RxNorm normalized name: Methylprednisolone
DrugBank: Methylprednisolone (DB00959)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intravenous methylprednisolone 2 mg/kg every four hours for 48 hours (group B)
Trial: 1412113
Drug: No intravenous
FDA approved: no
EMA approved: no
PMDA approved: no
Description: No intravenous corticosteroids (group C)
Trial: 31416155
Drug: Vitamin D3
RxNorm normalized name: Vitamin D3
DrugBank: Cholecalciferol (DB00169)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Vitamin D3 20,000 IU/week (in subgroup with baseline 25(OH)D <50 nmol/L)
Trial: 27390052
Drug: MK0431A 50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MK0431A 50 mg/500 mg tablet
Trial: 27390052
Drug: MK0431A 50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: MK0431A 50 mg/850 mg tablet
Trial: 24758075
Drug: MTX +
RxNorm normalized name: MTX
DrugBank: Methotrexate (DB00563)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: MTX + LEF therapy
Trial: 22643324
Drug: AAQ +
RxNorm normalized name: Abiraterone Acetate
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: AAQ + AMX (artesunate-amodiaquine plus amoxicillin)
Trial: 18953863
Drug: Oral lamivudine
RxNorm normalized name: Lamivudine
DrugBank: Lamivudine (DB00709)
FDA approved: yes
EMA approved: yes
PMDA approved: yes
Description: Oral lamivudine (100 mg/d)
Trial: 10760037
Drug: IFN-alpha with
RxNorm normalized name: IFN .ALPHA.-1B
DrugBank: Interferon alfa-1b (DB18522)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: IFN-alpha with ribavirin (1-1.2 g per day)
Trial: 7721636
Drug: High dose
RxNorm normalized name: INFLUENZA VACCINE HIGH DOSE 0.5ML SYR
FDA approved: no
EMA approved: no
PMDA approved: no
Description: High dose irradiation (75.6 CGE) using conformal protons
Trial: 7721636
Drug: Conventional dose
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional dose irradiation (67.2 Gy) using photons
Trial: 1976343
Drug: terfenadine 180
FDA approved: no
EMA approved: no
PMDA approved: no
Description: terfenadine 180 mg three times daily
Trial: 31742459
Drug: Pro-vaccine posts
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Pro-vaccine posts
Trial: 31742459
Drug: Anti-vaccine posts
RxNorm normalized name: post oak pollen extract
DrugBank: Quercus stellata pollen (DB10888)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Anti-vaccine posts
Trial: 28029173
Drug: Topiramate (up
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Topiramate (up to 200 mg/d)
Trial: 21733570
Drug: Prednisone (0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Prednisone (0.5 mg/kg daily for 8 months)
Trial: 21733570
Drug: Tamoxifen (0.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tamoxifen (0.5 mg/kg daily for 8 months)
Trial: 19863338
Drug: ABVD consolidation
RxNorm normalized name: BAG,LEG LARGE CONSOLIDATED #0932
FDA approved: no
EMA approved: no
PMDA approved: no
Description: ABVD consolidation therapy
Trial: 19863338
Drug: Radiation therapy
RxNorm normalized name: Sensitizers used in photodynamic/radiation therapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Radiation therapy (RT) consolidation
Trial: 8137469
Drug: Combination therapy
RxNorm normalized name: REGN10933+REGN10987 combination therapy
DrugBank: Anti-SARS-CoV-2 REGN-COV2 (DB15691)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Combination therapy of TACE followed by PEI
Trial: 6137969
Drug: Midazolam 0.07
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Midazolam 0.07 mg/kg
Trial: 2913250
Drug: Midazolam 0.13
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Midazolam 0.13 mg/kg
Trial: 349395
Drug: X-ray therapy
RxNorm normalized name: lactose, x-ray exposed (1000 rad)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: X-ray therapy (XRT)
Trial: 29117336
Drug: Paclitaxel/carboplatin treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Paclitaxel/carboplatin treatment
Trial: 29117336
Drug: Older age,
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Older age, bevacizumab treatment, bowel resection
Trial: 24432669
Drug: Sulfasalazine enteric‐coated
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sulfasalazine enteric‐coated tablet (SECT)
Trial: 22900440
Drug: Xylitol treatment
RxNorm normalized name: Xylitol
DrugBank: Xylitol (DB11195)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Xylitol treatment (chewing gum for mothers and tablets for children, consumed three times/day for three months)
Trial: 22900440
Drug: Xylitol treatment
RxNorm normalized name: Xylitol
DrugBank: Xylitol (DB11195)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Xylitol treatment (experimental group)
Trial: 20183464
Drug: Complete case
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Complete case (CC) analysis of covariance (ANCOVA)
Trial: 17166358
Drug: Intensive insulin
RxNorm normalized name: INSULIN
DrugBank: Insulin beef (DB09456)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Intensive insulin therapy (infusion of insulin if blood glucose >6.1 mmol/L, maintenance at 4.4‐6.1 mmol/L)
Trial: 17166358
Drug: Conventional treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Conventional treatment (infusion of insulin if blood glucose >11.9 mmol/L, maintenance at 10.0‐11.1 mmol/L)
Trial: 8707580
Drug: Dimethindene maleate
RxNorm normalized name: dimethindene maleate
DrugBank: Dimetindene (DB08801)
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dimethindene maleate (Fenistil gel)
Trial: 9413892
Drug: Xylocain ointment
RxNorm normalized name: Xylocaine
DrugBank: Lidocaine (DB00281)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Xylocain ointment 5%
Trial: 8214944
Drug: Methylprednisolone (MP)
RxNorm normalized name: Methylprednisolone
DrugBank: Methylprednisolone (DB00959)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Methylprednisolone (MP) pretreatment (30 mg/kg)
Trial: 8924134
Drug: Non-steroid treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Non-steroid treatment (Control)
Trial: 21666396
Drug: Glow gel
RxNorm normalized name: Coppertone Glow Gel SPF 30
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Glow gel hand washing without hand hygiene education
Trial: 21666396
Drug: Glow gel
RxNorm normalized name: Coppertone Glow Gel SPF 30
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Glow gel hand washing with hand hygiene education
Trial: 18443512
Drug: Surgical treatment
RxNorm normalized name: Hongo Killer Treatment
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Surgical treatment for chronic postoperative groin pain
Trial: 17163237
Drug: Alendronic acid
RxNorm normalized name: Alendronic Acid
DrugBank: Alendronic acid (DB00630)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Alendronic acid 70 mg weekly
Trial: 17163237
Drug: Risedronic acid
RxNorm normalized name: Risedronic acid
DrugBank: Risedronic acid (DB00884)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Risedronic acid 35 mg weekly
Trial: 2069096
Drug: Tebufelone 50
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tebufelone 50 mg
Trial: 2069096
Drug: Tebufelone 100
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tebufelone 100 mg
Trial: 2069096
Drug: Tebufelone 200
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tebufelone 200 mg
Trial: 2069096
Drug: Tebufelone 25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tebufelone 25 mg
Trial: 2069096
Drug: 650 mg
RxNorm normalized name: bran 650 MG
FDA approved: no
EMA approved: no
PMDA approved: no
Description: 650 mg ASA
Trial: 7049154
Drug: Multiload Copper
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Multiload Copper 250 (ML Cu 250)
Trial: 31322739
Drug: Patisiran 0.3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Patisiran 0.3 mg/kg intravenously every 3 weeks over 18 months
Trial: 31322739
Drug: Patisiran 0.3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Patisiran 0.3 mg/kg
Trial: 30496705
Drug: Montmorency cherry
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Montmorency cherry (MC) supplementation (235 mg/day anthocyanins)
Trial: 29391271
Drug: Eicosapentaenoic acid
RxNorm normalized name: eicosapentaenoic acid
DrugBank: Icosapent (DB00159)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: Eicosapentaenoic acid (EPA-FFA) 500 mg, twice daily for 6 months
Trial: 20026571
Drug: Exercise and
RxNorm normalized name: cytarabine and daunorubicin
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Exercise and education schemes held twice weekly for eight weeks
Trial: 11300442
Drug: Abciximab (bolus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Abciximab (bolus 0.25 mg/kg body weight, infusion 10 microg per min for 12 h)
Trial: 11300442
Drug: Tirofiban (bolus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Tirofiban (bolus 10 microg/kg, infusion 0.15 microg/kg per min for 72 h)
Trial: 11300442
Drug: Eptifibatide (bolus
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Eptifibatide (bolus 180 microg/kg, infusion 2 microg/kg per min for 72 h)
Trial: 3522528
Drug: Timentin (3
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Timentin (3 g/200 mg injections)
Trial: 3522528
Drug: Cefamandole (0.75
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Cefamandole (0.75 g injections)
Trial: 31609301
Drug: L-Tyrosine (150
FDA approved: no
EMA approved: no
PMDA approved: no
Description: L-Tyrosine (150 mg·kg)
Trial: 29498933
Drug: myo-inositol +
RxNorm normalized name: myo-inositol
DrugBank: Inositol (DB13178)
FDA approved: yes
EMA approved: no
PMDA approved: no
Description: myo-inositol + folic acid (4000 mg myo-inositol + 400 μg folic acid per day)
Trial: 25659187
Drug: Ziprasidone monotherapy
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Ziprasidone monotherapy for 12 weeks
Trial: 20692693
Drug: PRB28 (peginterferon
FDA approved: no
EMA approved: no
PMDA approved: no
Description: PRB28 (peginterferon alfa‐2b, ribavirin, and boceprevir 800 mg three times a day for 28 weeks)
Trial: 20692693
Drug: low-dose PRB48
RxNorm normalized name: ethinyl estradiol
DrugBank: Ethinylestradiol (DB00977)
FDA approved: yes
EMA approved: no
PMDA approved: yes
Description: low-dose PRB48 (low-dose ribavirin plus peginterferon alfa‐2b and boceprevir for 48 weeks)
Trial: 26854486
Drug: Isotretinoin (0.25
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Isotretinoin (0.25 mg/kg/day)
Trial: 20524999
Drug: Zoledronic acid
RxNorm normalized name: Zoledronic Acid
DrugBank: Zoledronic acid (DB00399)
FDA approved: yes
EMA approved: yes
PMDA approved: no
Description: Zoledronic acid (0.066 mg/kg, max 4 mg)
Trial: 16624969
Drug: Sunscreen use
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Sunscreen use daily
Trial: 12654707
Drug: Candesartan (800
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Candesartan (800 microg/min) + L-NMMA (7 micromol/min)
Trial: 10919416
Drug: Amrinone (1.5
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Amrinone (1.5 mg x kg(‐1) bolus over 15 min, followed by 10 microg x kg(‐1) x min(‐1) infusion)
Trial: 10919416
Drug: Placebo (equal
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Placebo (equal volume bolus followed by placebo infusion)
Trial: 8979280
Drug: Dapiprazole 0.5%
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Dapiprazole 0.5% eye drops administered 3 times daily as adjunctive therapy to timolol 0.5% eye drops twice daily
Trial: 6723452
Drug: Control group
RxNorm normalized name: meningococcal group B vaccine Prefilled Syringe [Trumenba]
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Control group (comparison treatments)
Trial: 30387335
Drug: Hyperbaric oxygen
FDA approved: no
EMA approved: no
PMDA approved: no
Description: Hyperbaric oxygen therapy (HBOT) after surgical excision and radiotherapy